Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6416
• Symbol:MAP2K4
• Description:mitogen-activated protein kinase kinase 4

DataSource: http://genomecrispr.dkfz.de/#!/results/MAP2K4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
12095571	12095594	17	+	26472758	Jiyoye	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.619421677425491	[264]	[306]	4	hSpCas9	negative selection	95906
12113319	12113342	17	+	26472758	Jiyoye	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.14815403817870276	[358]	[299]	1	hSpCas9	negative selection	95907
12129257	12129280	17	-	26472758	Jiyoye	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	0.13708621813812916	[204]	[169]	1	hSpCas9	negative selection	95908
12020976	12020999	17	-	26472758	Jiyoye	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	1.425553910820728	[77]	[157]	8	hSpCas9	negative selection	95909
12081447	12081470	17	+	26472758	Jiyoye	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	-0.5369713837606092	[151]	[78]	-4	hSpCas9	negative selection	95910
12125306	12125329	17	+	26472758	Jiyoye	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	1.8334401362079715	[47]	[128]	8	hSpCas9	negative selection	95911
12125338	12125361	17	-	26472758	Jiyoye	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	1.0694799707601943	[114]	[181]	7	hSpCas9	negative selection	95912
12020887	12020910	17	+	26472758	Jiyoye	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	-1.5596577545589272	[171]	[43]	-7	hSpCas9	negative selection	95913
12129149	12129172	17	-	26472758	Jiyoye	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	-0.5064098666766532	[161]	[85]	-4	hSpCas9	negative selection	95914
12095673	12095696	17	+	26472758	Jiyoye	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	-0.03248756606630954	[452]	[333]	0	hSpCas9	negative selection	95915
12095571	12095594	17	+	26472758	KBM7	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.5313430895969984	[1014,891]	[904,415]	6	hSpCas9	negative selection	287024
12113319	12113342	17	+	26472758	KBM7	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.3249068415211982	[1362,1870]	[1023,925]	3	hSpCas9	negative selection	287025
12129257	12129280	17	-	26472758	KBM7	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	0.45500443453174705	[448,394]	[336,212]	5	hSpCas9	negative selection	287026
12020976	12020999	17	-	26472758	KBM7	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.33753440948593755	[732,422]	[209,447]	3	hSpCas9	negative selection	287027
12081447	12081470	17	+	26472758	KBM7	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.1003791612914901	[349,340]	[197,153]	1	hSpCas9	negative selection	287028
12125306	12125329	17	+	26472758	KBM7	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	1.2347593017424237	[552,496]	[710,463]	9	hSpCas9	negative selection	287029
12125338	12125361	17	-	26472758	KBM7	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	-0.11840094506849719	[721,796]	[308,352]	-1	hSpCas9	negative selection	287030
12020887	12020910	17	+	26472758	KBM7	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.04828923842538865	[624,441]	[225,282]	0	hSpCas9	negative selection	287031
12129149	12129172	17	-	26472758	KBM7	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	0.9795485361952992	[384,275]	[250,348]	9	hSpCas9	negative selection	287032
12095673	12095696	17	+	26472758	KBM7	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.46287553118417346	[1951,1420]	[954,1192]	5	hSpCas9	negative selection	287033
12095571	12095594	17	+	26472758	Raji	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.5981635970380481	[537]	[188]	5	hSpCas9	negative selection	478142
12113319	12113342	17	+	26472758	Raji	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.04431417034883789	[864]	[206]	0	hSpCas9	negative selection	478143
12129257	12129280	17	-	26472758	Raji	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	0.1777728632649974	[239]	[62]	1	hSpCas9	negative selection	478144
12020976	12020999	17	-	26472758	Raji	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.0962715802533749	[390]	[96]	0	hSpCas9	negative selection	478145
12081447	12081470	17	+	26472758	Raji	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.2799629902618897	[180]	[50]	2	hSpCas9	negative selection	478146
12125306	12125329	17	+	26472758	Raji	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.39530911674910396	[248]	[75]	4	hSpCas9	negative selection	478147
12125338	12125361	17	-	26472758	Raji	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	0.18301797321045066	[352]	[92]	1	hSpCas9	negative selection	478148
12020887	12020910	17	+	26472758	Raji	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	-0.3617306366610369	[298]	[53]	-3	hSpCas9	negative selection	478149
12129149	12129172	17	-	26472758	Raji	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	0.13583998142282755	[250]	[63]	1	hSpCas9	negative selection	478150
12095673	12095696	17	+	26472758	Raji	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.23539114774967107	[969]	[264]	2	hSpCas9	negative selection	478151
12095571	12095594	17	+	26472758	K562	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.3780971628984162	[926]	[1016]	3	hSpCas9	negative selection	669260
12113319	12113342	17	+	26472758	K562	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.20066419779001743	[1338]	[1298]	1	hSpCas9	negative selection	669261
12129257	12129280	17	-	26472758	K562	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	-0.0006937701700846159	[383]	[323]	0	hSpCas9	negative selection	669262
12020976	12020999	17	-	26472758	K562	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.7828886431451516	[472]	[686]	6	hSpCas9	negative selection	669263
12081447	12081470	17	+	26472758	K562	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.5693808826434423	[284]	[356]	4	hSpCas9	negative selection	669264
12125306	12125329	17	+	26472758	K562	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.04940274526130409	[434]	[379]	0	hSpCas9	negative selection	669265
12125338	12125361	17	-	26472758	K562	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	0.10239972279401882	[543]	[492]	0	hSpCas9	negative selection	669266
12020887	12020910	17	+	26472758	K562	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.01396653653604732	[358]	[305]	0	hSpCas9	negative selection	669267
12129149	12129172	17	-	26472758	K562	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	0.06625444031821623	[438]	[387]	0	hSpCas9	negative selection	669268
12095673	12095696	17	+	26472758	K562	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.7617872802525543	[1288]	[1844]	6	hSpCas9	negative selection	669269
12095571	12095594	17	+	26627737	DLD1	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.08565028077793646	[1799]	[619,827,385]	0	hSpCas9	negative selection	796127
12095673	12095696	17	+	26627737	DLD1	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.8670797594989083	[631]	[276,546,277]	8	hSpCas9	negative selection	796128
12125306	12125329	17	+	26627737	DLD1	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.5359874130560935	[948]	[296,203,124]	-5	hSpCas9	negative selection	796129
12129133	12129156	17	+	26627737	DLD1	viability	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	0.07563706846746071	[360]	[98,65,179]	0	hSpCas9	negative selection	796130
12141235	12141258	17	-	26627737	DLD1	viability	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	-0.19660519857930137	[341]	[62,41,161]	-2	hSpCas9	negative selection	796131
12095571	12095594	17	+	26627737	GBM cells	viability after 5 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.4371281164153624	[804]	[489,678]	6	hSpCas9	negative selection	878442
12095673	12095696	17	+	26627737	GBM cells	viability after 5 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.397007113892088	[404]	[281,289]	6	hSpCas9	negative selection	878443
12125306	12125329	17	+	26627737	GBM cells	viability after 5 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.6538013770491541	[239]	[197,206]	8	hSpCas9	negative selection	878444
12129133	12129156	17	+	26627737	GBM cells	viability after 5 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	0.5743886685122841	[138]	[131,89]	8	hSpCas9	negative selection	878445
12141235	12141258	17	-	26627737	GBM cells	viability after 5 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	0.7958203819215819	[86]	[93,67]	9	hSpCas9	negative selection	878446
12095571	12095594	17	+	26627737	GBM cells	viability after 13 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.6360415189229915	[804]	[707,654]	7	hSpCas9	negative selection	960757
12095673	12095696	17	+	26627737	GBM cells	viability after 13 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.6412759806120906	[404]	[366,322]	7	hSpCas9	negative selection	960758
12125306	12125329	17	+	26627737	GBM cells	viability after 13 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.014300503140235545	[239]	[134,123]	0	hSpCas9	negative selection	960759
12129133	12129156	17	+	26627737	GBM cells	viability after 13 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	1.0455691482394762	[138]	[201,117]	9	hSpCas9	negative selection	960760
12141235	12141258	17	-	26627737	GBM cells	viability after 13 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	0.7746813455050813	[86]	[77,82]	8	hSpCas9	negative selection	960761
12095571	12095594	17	+	26627737	GBM cells	viability after 21 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.9992262310974682	[804]	[927,824]	8	hSpCas9	negative selection	1043072
12095673	12095696	17	+	26627737	GBM cells	viability after 21 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.9851313354895693	[404]	[457,414]	8	hSpCas9	negative selection	1043073
12125306	12125329	17	+	26627737	GBM cells	viability after 21 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	1.2549379302161203	[239]	[306,314]	9	hSpCas9	negative selection	1043074
12129133	12129156	17	+	26627737	GBM cells	viability after 21 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	1.6998263412990404	[138]	[272,219]	9	hSpCas9	negative selection	1043075
12141235	12141258	17	-	26627737	GBM cells	viability after 21 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	1.3623661506508584	[86]	[120,121]	9	hSpCas9	negative selection	1043076
12095571	12095594	17	+	26627737	RPE1	viability after 9 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.038756777716375534	[2421]	[659,838]	0	hSpCas9	negative selection	1125387
12095673	12095696	17	+	26627737	RPE1	viability after 9 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.48733930870856224	[1452]	[452,875]	3	hSpCas9	negative selection	1125388
12125306	12125329	17	+	26627737	RPE1	viability after 9 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.43670778979651814	[2035]	[404,555]	-3	hSpCas9	negative selection	1125389
12129133	12129156	17	+	26627737	RPE1	viability after 9 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.2978823384169166	[467]	[85,161]	-2	hSpCas9	negative selection	1125390
12141235	12141258	17	-	26627737	RPE1	viability after 9 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	-0.11393828286702129	[712]	[214,194]	-1	hSpCas9	negative selection	1125391
12095571	12095594	17	+	26627737	RPE1	viability after 12 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.30901997416555615	[2421]	[929,674]	2	hSpCas9	negative selection	1207702
12095673	12095696	17	+	26627737	RPE1	viability after 12 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.92189383855713	[1452]	[640,843]	6	hSpCas9	negative selection	1207703
12125306	12125329	17	+	26627737	RPE1	viability after 12 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.6011548478575783	[2035]	[329,392]	-4	hSpCas9	negative selection	1207704
12129133	12129156	17	+	26627737	RPE1	viability after 12 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.5609880625200206	[467]	[41,130]	-4	hSpCas9	negative selection	1207705
12141235	12141258	17	-	26627737	RPE1	viability after 12 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	-0.6056760920148339	[712]	[87,165]	-4	hSpCas9	negative selection	1207706
12095571	12095594	17	+	26627737	RPE1	viability after 15 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.11533140184691493	[2421]	[789,695]	0	hSpCas9	negative selection	1290017
12095673	12095696	17	+	26627737	RPE1	viability after 15 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	1.3325688295912235	[1452]	[997,1070]	7	hSpCas9	negative selection	1290018
12125306	12125329	17	+	26627737	RPE1	viability after 15 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.07902396766630271	[2035]	[643,573]	0	hSpCas9	negative selection	1290019
12129133	12129156	17	+	26627737	RPE1	viability after 15 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.6761348385869189	[467]	[62,101]	-4	hSpCas9	negative selection	1290020
12141235	12141258	17	-	26627737	RPE1	viability after 15 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	-0.6290291227455632	[712]	[106,152]	-4	hSpCas9	negative selection	1290021
12095571	12095594	17	+	26627737	RPE1	viability after 18 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.11999577573202247	[2421]	[631,793]	0	hSpCas9	negative selection	1372332
12095673	12095696	17	+	26627737	RPE1	viability after 18 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	1.3805092708101574	[1452]	[1076,960]	7	hSpCas9	negative selection	1372333
12125306	12125329	17	+	26627737	RPE1	viability after 18 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.01239369128178791	[2035]	[318,785]	0	hSpCas9	negative selection	1372334
12129133	12129156	17	+	26627737	RPE1	viability after 18 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.9169563535366981	[467]	[19,116]	-5	hSpCas9	negative selection	1372335
12141235	12141258	17	-	26627737	RPE1	viability after 18 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	-0.7195965626618495	[712]	[126,105]	-4	hSpCas9	negative selection	1372336
12095571	12095594	17	+	26627737	HeLa	viability after 8 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.1449947195621888	[1436]	[600,636,472]	-1	hSpCas9	negative selection	1454647
12095673	12095696	17	+	26627737	HeLa	viability after 8 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.1151733810811385	[656]	[597,241,162]	1	hSpCas9	negative selection	1454648
12125306	12125329	17	+	26627737	HeLa	viability after 8 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.5792424996305396	[908]	[470,242,134]	-5	hSpCas9	negative selection	1454649
12129133	12129156	17	+	26627737	HeLa	viability after 8 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.07526916051622234	[209]	[176,44,59]	0	hSpCas9	negative selection	1454650
12141235	12141258	17	-	26627737	HeLa	viability after 8 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	1.0634615835723629	[74]	[10,67,109]	7	hSpCas9	negative selection	1454651
12095571	12095594	17	+	26627737	HeLa	viability after 12 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.3429405718536791	[1436]	[491,480,430]	-3	hSpCas9	negative selection	1536962
12095673	12095696	17	+	26627737	HeLa	viability after 12 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	-0.04221045549491087	[656]	[362,215,219]	0	hSpCas9	negative selection	1536963
12125306	12125329	17	+	26627737	HeLa	viability after 12 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.9932526532204385	[908]	[167,221,171]	-7	hSpCas9	negative selection	1536964
12129133	12129156	17	+	26627737	HeLa	viability after 12 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	0.6926153731102175	[209]	[286,36,111]	5	hSpCas9	negative selection	1536965
12141235	12141258	17	-	26627737	HeLa	viability after 12 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	1.3068021318936334	[74]	[89,108,27]	8	hSpCas9	negative selection	1536966
12095571	12095594	17	+	26627737	HeLa	viability after 15 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.003923476605203202	[1436]	[396,586,783]	0	hSpCas9	negative selection	1619277
12095673	12095696	17	+	26627737	HeLa	viability after 15 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	-0.3599857447578925	[656]	[135,210,284]	-3	hSpCas9	negative selection	1619278
12125306	12125329	17	+	26627737	HeLa	viability after 15 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.8017014360194105	[908]	[172,304,154]	-6	hSpCas9	negative selection	1619279
12129133	12129156	17	+	26627737	HeLa	viability after 15 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.11363430401024766	[209]	[89,102,40]	-1	hSpCas9	negative selection	1619280
12141235	12141258	17	-	26627737	HeLa	viability after 15 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	1.0525731820517863	[74]	[24,95,69]	7	hSpCas9	negative selection	1619281
12095571	12095594	17	+	26627737	HeLa	viability after 18 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.034261408347403766	[1436]	[245,481,783]	0	hSpCas9	negative selection	1701592
12095673	12095696	17	+	26627737	HeLa	viability after 18 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	-0.398293754773852	[656]	[81,172,284]	-3	hSpCas9	negative selection	1701593
12125306	12125329	17	+	26627737	HeLa	viability after 18 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.8189783436214313	[908]	[105,258,154]	-6	hSpCas9	negative selection	1701594
12129133	12129156	17	+	26627737	HeLa	viability after 18 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.14031564782791772	[209]	[56,85,40]	-1	hSpCas9	negative selection	1701595
12141235	12141258	17	-	26627737	HeLa	viability after 18 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	1.121555884107646	[74]	[19,82,69]	7	hSpCas9	negative selection	1701596
12095571	12095594	17	+	26627737	HCT116	viability after 6 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.8820365672677843	[2393]	[1439,281]	5	hSpCas9	negative selection	1783907
12095673	12095696	17	+	26627737	HCT116	viability after 6 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	-0.545395695554965	[891]	[253,8]	-3	hSpCas9	negative selection	1783908
12125306	12125329	17	+	26627737	HCT116	viability after 6 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	1.0584903718541334	[821]	[622,73]	6	hSpCas9	negative selection	1783909
12129133	12129156	17	+	26627737	HCT116	viability after 6 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-3.222011669725807	[363]	[9,3]	-9	hSpCas9	negative selection	1783910
12141235	12141258	17	-	26627737	HCT116	viability after 6 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	1.8739475229112887	[389]	[2,346]	8	hSpCas9	negative selection	1783911
12095571	12095594	17	+	26627737	HCT116	viability after 8 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.05361390356811779	[1156]	[541,804,495]	0	hSpCas9	negative selection	1866222
12095673	12095696	17	+	26627737	HCT116	viability after 8 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.30460252356596573	[477]	[361,323,290]	3	hSpCas9	negative selection	1866223
12125306	12125329	17	+	26627737	HCT116	viability after 8 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.17872275988747754	[573]	[335,279,223]	-2	hSpCas9	negative selection	1866224
12129133	12129156	17	+	26627737	HCT116	viability after 8 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.5895504771147166	[260]	[63,195,26]	-6	hSpCas9	negative selection	1866225
12141235	12141258	17	-	26627737	HCT116	viability after 8 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	-1.0921353165297534	[186]	[11,54,76]	-8	hSpCas9	negative selection	1866226
12095571	12095594	17	+	26627737	HCT116	viability after 9 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.014176469092357813	[2393]	[923,402]	0	hSpCas9	negative selection	1948537
12095673	12095696	17	+	26627737	HCT116	viability after 9 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	-0.0666730468640172	[891]	[251,207]	0	hSpCas9	negative selection	1948538
12125306	12125329	17	+	26627737	HCT116	viability after 9 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.6402277291379317	[821]	[531,191]	4	hSpCas9	negative selection	1948539
12129133	12129156	17	+	26627737	HCT116	viability after 9 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-2.9688605224910427	[363]	[17,7]	-9	hSpCas9	negative selection	1948540
12141235	12141258	17	-	26627737	HCT116	viability after 9 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	0.44630783941575536	[389]	[285,27]	3	hSpCas9	negative selection	1948541
12095571	12095594	17	+	26627737	HCT116	viability after 12 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.08765663930525358	[1156]	[704,637,589]	0	hSpCas9	negative selection	2030852
12095673	12095696	17	+	26627737	HCT116	viability after 12 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.03808530684936129	[477]	[300,299,169]	0	hSpCas9	negative selection	2030853
12125306	12125329	17	+	26627737	HCT116	viability after 12 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.0028829500199502034	[573]	[414,253,222]	0	hSpCas9	negative selection	2030854
12129133	12129156	17	+	26627737	HCT116	viability after 12 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.6315304827473035	[260]	[86,98,79]	-6	hSpCas9	negative selection	2030855
12141235	12141258	17	-	26627737	HCT116	viability after 12 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	-0.8435724337861843	[186]	[21,88,56]	-7	hSpCas9	negative selection	2030856
12095571	12095594	17	+	26627737	HCT116	viability after 15 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.027318439812012763	[1156]	[599,559,787]	0	hSpCas9	negative selection	2113167
12095673	12095696	17	+	26627737	HCT116	viability after 15 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.03251458100561522	[477]	[302,259,281]	0	hSpCas9	negative selection	2113168
12125306	12125329	17	+	26627737	HCT116	viability after 15 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.20169396724814237	[573]	[415,284,175]	-2	hSpCas9	negative selection	2113169
12129133	12129156	17	+	26627737	HCT116	viability after 15 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.4327922858415505	[260]	[121,145,66]	-4	hSpCas9	negative selection	2113170
12141235	12141258	17	-	26627737	HCT116	viability after 15 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	-0.7129312605221436	[186]	[57,101,35]	-6	hSpCas9	negative selection	2113171
12095571	12095594	17	+	26627737	HCT116	viability after 18 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.200270929396833	[1156]	[601,598,733]	1	hSpCas9	negative selection	2195482
12095673	12095696	17	+	26627737	HCT116	viability after 18 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.07399165793359297	[477]	[149,287,290]	0	hSpCas9	negative selection	2195483
12125306	12125329	17	+	26627737	HCT116	viability after 18 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.18793465045413782	[573]	[312,422,199]	1	hSpCas9	negative selection	2195484
12129133	12129156	17	+	26627737	HCT116	viability after 18 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.9570019370133529	[260]	[74,77,39]	-7	hSpCas9	negative selection	2195485
12141235	12141258	17	-	26627737	HCT116	viability after 18 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	0.3492046292302789	[186]	[21,208,107]	3	hSpCas9	negative selection	2195486
12020887	12020910	17	+	24336569	HL60	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.8759963544065786	[412]	[1603]	7	hSpCas9	negative selection	2275778
12020971	12020994	17	-	24336569	HL60	viability	CTGCTGACGGCCGGGTGGCCTGG	MAP2K4	ENSG00000065559	0.46374775110465144	[600]	[1753]	4	hSpCas9	negative selection	2275779
12020976	12020999	17	-	24336569	HL60	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.6677088714329338	[964]	[3243]	6	hSpCas9	negative selection	2275780
12054983	12055006	17	-	24336569	HL60	viability	CCAAGAATACTCACATGTGTGGG	MAP2K4	ENSG00000065559	0.4371864042814051	[370]	[1062]	4	hSpCas9	negative selection	2275781
12081447	12081470	17	+	24336569	HL60	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.7413208619983138	[464]	[1644]	6	hSpCas9	negative selection	2275782
12081456	12081479	17	+	24336569	HL60	viability	GAAATTGGACGAGGAGCTTATGG	MAP2K4	ENSG00000065559	0.8302994259415919	[1398]	[5263]	6	hSpCas9	negative selection	2275783
12095571	12095594	17	+	24336569	HL60	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	2.383421948100509	[71]	[794]	9	hSpCas9	negative selection	2275784
12095621	12095644	17	+	24336569	HL60	viability	TGGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	0.5952945645000858	[892]	[2854]	5	hSpCas9	negative selection	2275785
12095673	12095696	17	+	24336569	HL60	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.14973421808289245	[1259]	[2957]	1	hSpCas9	negative selection	2275786
12107789	12107812	17	+	24336569	HL60	viability	GGGTGACTGTTGGATCTGTATGG	MAP2K4	ENSG00000065559	-0.8632839305793628	[930]	[1082]	-7	hSpCas9	negative selection	2275787
12020887	12020910	17	+	24336569	KBM7	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.3477940443717143	[379]	[1318]	3	hSpCas9	negative selection	2342955
12020971	12020994	17	-	24336569	KBM7	viability	CTGCTGACGGCCGGGTGGCCTGG	MAP2K4	ENSG00000065559	0.8653194840461587	[576]	[2866]	7	hSpCas9	negative selection	2342956
12020976	12020999	17	-	24336569	KBM7	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.35153091911319545	[726]	[2529]	3	hSpCas9	negative selection	2342957
12054983	12055006	17	-	24336569	KBM7	viability	CCAAGAATACTCACATGTGTGGG	MAP2K4	ENSG00000065559	-0.1422707232310047	[453]	[1121]	-1	hSpCas9	negative selection	2342958
12081447	12081470	17	+	24336569	KBM7	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	-0.23290781227648757	[454]	[1055]	-2	hSpCas9	negative selection	2342959
12081456	12081479	17	+	24336569	KBM7	viability	GAAATTGGACGAGGAGCTTATGG	MAP2K4	ENSG00000065559	0.40332539330317285	[1486]	[5363]	4	hSpCas9	negative selection	2342960
12095571	12095594	17	+	24336569	KBM7	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	1.1945686507634807	[168]	[1054]	8	hSpCas9	negative selection	2342961
12095621	12095644	17	+	24336569	KBM7	viability	TGGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	0.45909812460571975	[901]	[3381]	4	hSpCas9	negative selection	2342962
12095673	12095696	17	+	24336569	KBM7	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.8653460919575272	[642]	[3194]	7	hSpCas9	negative selection	2342963
12107789	12107812	17	+	24336569	KBM7	viability	GGGTGACTGTTGGATCTGTATGG	MAP2K4	ENSG00000065559	0.6119541267607363	[450]	[1879]	5	hSpCas9	negative selection	2342964
12073814	12073837	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACGCCACTGCACTCCAGCCCAG	MAP2K4	ENSG00000065559	-0.23120917697478569	[21,115]	[6,17]	-1	dCas9-VP64	positive selection	2389317
12133130	12133153	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGTAGTGGCGCGATCTCAG	MAP2K4	ENSG00000065559	3.1722237697093507	[103,9]	[210,6]	8	dCas9-VP64	positive selection	2392253
12110004	12110027	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTTGGCAGGCTGTGG	MAP2K4	ENSG00000065559	2.180224224283918	[67,41]	[97,7]	7	dCas9-VP64	positive selection	2393017
12073814	12073837	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACGCCACTGCACTCCAGCCCAG	MAP2K4	ENSG00000065559	-0.7543799798568478	[117,158]	[37,14]	-7	dCas9-VP64	positive selection	2484572
12133130	12133153	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGTAGTGGCGCGATCTCAG	MAP2K4	ENSG00000065559	0.8627698723325049	[50,145]	[36,76]	6	dCas9-VP64	positive selection	2487508
12110004	12110027	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTTGGCAGGCTGTGG	MAP2K4	ENSG00000065559	0.5215654761973469	[134,134]	[72,52]	4	dCas9-VP64	positive selection	2488272
12081448	12081471	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	-1.1271378242416752e-05	[1,2]	[3,0]	0	hSpCas9	positive selection	3001114
12020976	12020999	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.3227160696428465	[2,2]	[3,1]	6	hSpCas9	positive selection	3001115
12081448	12081471	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	-0.3635014633291054	[1,1]	[0,0]	-5	hSpCas9	positive selection	3068972
12020976	12020999	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.5609360126282068	[2,2]	[1,2]	8	hSpCas9	positive selection	3068973
12113323	12113346		-	24336571	A375	resistance to PLX after 7 days	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	-0.27373634700867433	[15,13]	[12,10]	-7	hSpCas9	positive selection	3126252
12113319	12113342		+	24336571	A375	resistance to PLX after 7 days	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	-0.18396836317666165	[8,7]	[6,7]	-6	hSpCas9	positive selection	3126253
12107824	12107847		-	24336571	A375	resistance to PLX after 7 days	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.1079162328877139	[2,3]	[2,2]	-3	hSpCas9	positive selection	3126254
12113323	12113346		-	24336571	A375	resistance to PLX after 14 days	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	-1.0297295418221173	[14,13]	[2,2]	-9	hSpCas9	positive selection	3184045
12113319	12113342		+	24336571	A375	resistance to PLX after 14 days	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	-0.5432306640368945	[8,8]	[1,2]	-6	hSpCas9	positive selection	3184046
12107824	12107847		-	24336571	A375	resistance to PLX after 14 days	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.8569069031601655	[1,3]	[1,1]	7	hSpCas9	positive selection	3184047
12113323	12113346		-	24336571	A375	viability after 7 days	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.3362138730113233	[11]	[15,13]	5	hSpCas9	negative selection	3241838
12113319	12113342		+	24336571	A375	viability after 7 days	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.10634771674906984	[7]	[8,7]	1	hSpCas9	negative selection	3241839
12107824	12107847		-	24336571	A375	viability after 7 days	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.06752799629005324	[3]	[2,3]	-1	hSpCas9	negative selection	3241840
12113323	12113346		-	24336571	A375	viability after 14 days	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.3420159057881196	[11]	[14,13]	4	hSpCas9	negative selection	3299631
12113319	12113342		+	24336571	A375	viability after 14 days	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.19306388800052515	[7]	[8,8]	2	hSpCas9	negative selection	3299632
12107824	12107847		-	24336571	A375	viability after 14 days	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.40586684610449497	[3]	[1,3]	-5	hSpCas9	negative selection	3299633
12107824	12107847	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	1.6426163673306269	[48,48]	[0,0]	6	hSpCas9	positive selection	3378379
12113323	12113346	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	-0.10899600279998067	[164,164]	[0,0]	0	hSpCas9	positive selection	3378380
12054925	12054948	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	3.89792341113981	[194,194]	[18,18]	9	hSpCas9	positive selection	3378381
12081406	12081429	17	-	26780180	HT29	viability (Avana library 4 designs)	GAAATCCCAGTGTTGTTCAGGGG	MAP2K4	ENSG00000065559	0.644157275701049	[]	[]	2	hSpCas9	negative selection	3438756
12081447	12081470	17	+	26780180	HT29	viability (Avana library 4 designs)	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	1.23106602032717	[]	[]	5	hSpCas9	negative selection	3438757
12020976	12020999	17	-	26780180	HT29	viability (Avana library 4 designs)	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	-0.399854726536363	[]	[]	-6	hSpCas9	negative selection	3438758
12081473	12081496	17	+	26780180	HT29	viability (Avana library 4 designs)	TTATGGTTCTGTCAACAAAATGG	MAP2K4	ENSG00000065559	1.68047039527746	[]	[]	6	hSpCas9	negative selection	3438759
12081473	12081496	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATGGTTCTGTCAACAAAATGG	MAP2K4	ENSG00000065559	-6.60952038611987	[]	[]	-6	hSpCas9	negative selection	3528165
12081406	12081429	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAAATCCCAGTGTTGTTCAGGGG	MAP2K4	ENSG00000065559	2.57343651367164	[]	[]	4	hSpCas9	negative selection	3528166
12020976	12020999	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	5.32515840064441	[]	[]	8	hSpCas9	negative selection	3528167
12081447	12081470	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	1.97305819613263	[]	[]	3	hSpCas9	negative selection	3528168
12081473	12081496	17	+	26780180	A375	viability (Avana lentiGuide)	TTATGGTTCTGTCAACAAAATGG	MAP2K4	ENSG00000065559	-7.27681180491372	[]	[]	-9	hSpCas9	negative selection	3636824
12081406	12081429	17	-	26780180	A375	viability (Avana lentiGuide)	GAAATCCCAGTGTTGTTCAGGGG	MAP2K4	ENSG00000065559	3.72682925206769	[]	[]	3	hSpCas9	negative selection	3636825
12020976	12020999	17	-	26780180	A375	viability (Avana lentiGuide)	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	-3.58188300641495	[]	[]	-6	hSpCas9	negative selection	3636826
12081447	12081470	17	+	26780180	A375	viability (Avana lentiGuide)	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	3.58624183269102	[]	[]	3	hSpCas9	negative selection	3636827
12081473	12081496	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATGGTTCTGTCAACAAAATGG	MAP2K4	ENSG00000065559	-0.6538684215312891	[6]	[5,2]	-7	hSpCas9	positive selection	3745483
12081406	12081429	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAATCCCAGTGTTGTTCAGGGG	MAP2K4	ENSG00000065559	0.024388558572812614	[4]	[5,4]	0	hSpCas9	positive selection	3745484
12020976	12020999	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.11349322291220398	[3]	[4,3]	3	hSpCas9	positive selection	3745485
12081447	12081470	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	-0.04479479836252989	[4]	[4,2]	0	hSpCas9	positive selection	3745486
12081473	12081496	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATGGTTCTGTCAACAAAATGG	MAP2K4	ENSG00000065559	0.2809131657597557	[4]	[5,4]	7	hSpCas9	positive selection	3854090
12081406	12081429	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAATCCCAGTGTTGTTCAGGGG	MAP2K4	ENSG00000065559	-0.6956288824772089	[5]	[3,1]	-7	hSpCas9	positive selection	3854091
12020976	12020999	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	-0.03966506028497718	[4]	[3,3]	0	hSpCas9	positive selection	3854092
12081447	12081470	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	-1.150904363832164	[3]	[1,0]	-8	hSpCas9	positive selection	3854093
12113323	12113346	17	-	26780180	A375	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	1.09919983833962	[]	[]	5	hSpCas9	negative selection	3959603
12054925	12054948	17	+	26780180	A375	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.208814323162735	[]	[]	0	hSpCas9	negative selection	3959604
12125306	12125329	17	+	26780180	A375	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	1.64413595432953	[]	[]	8	hSpCas9	negative selection	3959605
12125309	12125332	17	-	26780180	A375	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.794079031634062	[]	[]	3	hSpCas9	negative selection	3959606
12113349	12113372	17	-	26780180	A375	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	-0.336942843535007	[]	[]	-8	hSpCas9	negative selection	3959607
12107824	12107847	17	-	26780180	A375	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.423987218624233	[]	[]	1	hSpCas9	negative selection	3959608
12113323	12113346	17	-	26780180	HT29	viability (GeCKOv2 library)	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.547928045318621	[]	[]	1	hSpCas9	negative selection	4067569
12054925	12054948	17	+	26780180	HT29	viability (GeCKOv2 library)	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.32352199244019	[]	[]	0	hSpCas9	negative selection	4067570
12125306	12125329	17	+	26780180	HT29	viability (GeCKOv2 library)	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	1.31372517771191	[]	[]	6	hSpCas9	negative selection	4067571
12125309	12125332	17	-	26780180	HT29	viability (GeCKOv2 library)	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.0189632722762164	[]	[]	0	hSpCas9	negative selection	4067572
12113349	12113372	17	-	26780180	HT29	viability (GeCKOv2 library)	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	-0.488575016716503	[]	[]	-9	hSpCas9	negative selection	4067573
12107824	12107847	17	-	26780180	HT29	viability (GeCKOv2 library)	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.811151837483286	[]	[]	3	hSpCas9	negative selection	4067574
12113323	12113346	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.047831855256820266	[2]	[2,1]	1	hSpCas9	positive selection	4150468
12113319	12113342	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	-0.31658852121547254	[3]	[1,1]	-7	hSpCas9	positive selection	4150469
12107824	12107847	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.27385700503916477	[1]	[1,0]	6	hSpCas9	positive selection	4150470
12113323	12113346	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.04458300148813632	[4]	[2,2,4,0]	0	hSpCas9	positive selection	4214490
12113319	12113342	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	-0.12882702696335796	[3]	[3,0,1,0]	-2	hSpCas9	positive selection	4214491
12107824	12107847	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.4975671085957587	[3]	[0,0,1,0]	-7	hSpCas9	positive selection	4214492
12125306	12125329	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.21129347231876086	[4]	[3,1]	-4	hSpCas9	positive selection	4281807
12125309	12125332	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.3250266997862006	[4]	[4,3]	6	hSpCas9	positive selection	4281808
12113349	12113372	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.0857975004925306	[4]	[5,2]	1	hSpCas9	positive selection	4281809
12107824	12107847	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.2796334265857091	[1]	[2,1]	5	hSpCas9	positive selection	4346065
12113323	12113346	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.01188014609407509	[2]	[2,0]	0	hSpCas9	positive selection	4346066
12054925	12054948	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.3991691778222233	[2]	[3,2]	7	hSpCas9	positive selection	4346067
12095572	12095594	17	+	27760321	OCIAML3	viability	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.3632524951637427	[919,735]	[627,1088]	4	hSpCas9	negative selection	4416555
12095622	12095644	17	+	27760321	OCIAML3	viability	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	0.07929376139872923	[92,88]	[73,76]	0	hSpCas9	negative selection	4416556
12107824	12107846	17	-	27760321	OCIAML3	viability	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.3726684944021672	[20,21]	[19,3]	-4	hSpCas9	negative selection	4416557
12110392	12110414	17	-	27760321	OCIAML3	viability	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	-1.8331112220604444	[3,4]	[0,0]	-9	hSpCas9	negative selection	4416558
12110410	12110432	17	+	27760321	OCIAML3	viability	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	0.37081628883410533	[203,197]	[227,171]	4	hSpCas9	negative selection	4416559
12095572	12095594	17	+	27760321	OCIAML2	viability	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.7319432558596423	[919,735]	[960,1296]	8	hSpCas9	negative selection	4500018
12095622	12095644	17	+	27760321	OCIAML2	viability	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	0.8753117122275855	[92,88]	[120,153]	9	hSpCas9	negative selection	4500019
12107824	12107846	17	-	27760321	OCIAML2	viability	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	1.0070335526119516	[20,21]	[35,33]	9	hSpCas9	negative selection	4500020
12110392	12110414	17	-	27760321	OCIAML2	viability	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	2.1857507126280042	[3,4]	[8,26]	9	hSpCas9	negative selection	4500021
12110410	12110432	17	+	27760321	OCIAML2	viability	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	0.2247756962406473	[203,197]	[151,240]	3	hSpCas9	negative selection	4500022
12095572	12095594	17	+	27760321	MV411	viability	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.9923760158558385	[919,735]	[1431,552]	7	hSpCas9	negative selection	4583481
12095622	12095644	17	+	27760321	MV411	viability	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	1.1733025467012754	[92,88]	[173,77]	8	hSpCas9	negative selection	4583482
12107824	12107846	17	-	27760321	MV411	viability	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-2.0693686538747835	[20,21]	[0,6]	-8	hSpCas9	negative selection	4583483
12110392	12110414	17	-	27760321	MV411	viability	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	-1.5880326531457625	[3,4]	[0,0]	-7	hSpCas9	negative selection	4583484
12110410	12110432	17	+	27760321	MV411	viability	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	0.8592437523259635	[203,197]	[139,392]	6	hSpCas9	negative selection	4583485
12095572	12095594	17	+	27760321	HL60	viability	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.17211129792800062	[919,735]	[490,708]	-2	hSpCas9	negative selection	4666944
12095622	12095644	17	+	27760321	HL60	viability	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	0.42742567838316514	[92,88]	[103,95]	5	hSpCas9	negative selection	4666945
12107824	12107846	17	-	27760321	HL60	viability	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	1.0190817302950355	[20,21]	[44,25]	9	hSpCas9	negative selection	4666946
12110392	12110414	17	-	27760321	HL60	viability	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	-0.2830420269682108	[3,4]	[4,0]	-3	hSpCas9	negative selection	4666947
12110410	12110432	17	+	27760321	HL60	viability	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	0.5837352566058903	[203,197]	[149,348]	7	hSpCas9	negative selection	4666948
12095572	12095594	17	+	27760321	HT1080	viability	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	1.6142325115068479	[735,574]	[925,660]	8	hSpCas9	negative selection	4750407
12095622	12095644	17	+	27760321	HT1080	viability	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	0.4951080978691944	[88,69]	[47,40]	2	hSpCas9	negative selection	4750408
12107824	12107846	17	-	27760321	HT1080	viability	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-2.95669589080409	[21,16]	[0,0]	-7	hSpCas9	negative selection	4750409
12110392	12110414	17	-	27760321	HT1080	viability	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	-0.8443172389209588	[4,3]	[0,0]	-4	hSpCas9	negative selection	4750410
12110410	12110432	17	+	27760321	HT1080	viability	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	1.9437024016757158	[197,154]	[323,211]	8	hSpCas9	negative selection	4750411
12095572	12095594	17	+	27760321	HT29	viability after 7 days	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.20591250815261153	[735,574]	[1437,620,923]	3	hSpCas9	negative selection	4833870
12095622	12095644	17	+	27760321	HT29	viability after 7 days	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	-0.6406035780785815	[88,69]	[30,70,88]	-7	hSpCas9	negative selection	4833871
12107824	12107846	17	-	27760321	HT29	viability after 7 days	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.8799882413107092	[21,16]	[25,15,0]	-8	hSpCas9	negative selection	4833872
12110392	12110414	17	-	27760321	HT29	viability after 7 days	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	1.1950847067959387	[4,3]	[11,26,0]	9	hSpCas9	negative selection	4833873
12110410	12110432	17	+	27760321	HT29	viability after 7 days	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	0.20772602527329975	[197,154]	[242,269,269]	3	hSpCas9	negative selection	4833874
12095572	12095594	17	+	27760321	HT29	viability after 25 days	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.8689798041724929	[735,574]	[1036,1705,1381]	8	hSpCas9	negative selection	4917333
12095622	12095644	17	+	27760321	HT29	viability after 25 days	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	0.5719987594816667	[88,69]	[178,65,159]	6	hSpCas9	negative selection	4917334
12107824	12107846	17	-	27760321	HT29	viability after 25 days	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.3904836518856465	[21,16]	[10,62,12]	4	hSpCas9	negative selection	4917335
12110392	12110414	17	-	27760321	HT29	viability after 25 days	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	-2.3639995037674826	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	4917336
12110410	12110432	17	+	27760321	HT29	viability after 25 days	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	0.028323222266645742	[197,154]	[164,252,200]	0	hSpCas9	negative selection	4917337
12095572	12095594	17	+	27760321	HT29	viability after 22 days	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.5078656372986071	[735,574]	[800,1177,1262]	5	hSpCas9	negative selection	5000796
12095622	12095644	17	+	27760321	HT29	viability after 22 days	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	0.5587968215446302	[88,69]	[192,52,158]	6	hSpCas9	negative selection	5000797
12107824	12107846	17	-	27760321	HT29	viability after 22 days	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.1450986335273745	[21,16]	[54,3,0]	-1	hSpCas9	negative selection	5000798
12110392	12110414	17	-	27760321	HT29	viability after 22 days	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	-1.971787434662824	[4,3]	[0,0,1]	-8	hSpCas9	negative selection	5000799
12110410	12110432	17	+	27760321	HT29	viability after 22 days	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	-0.060262415962330174	[197,154]	[139,220,227]	0	hSpCas9	negative selection	5000800
12095572	12095594	17	+	27760321	HT29	viability after 19 days	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.7749890448451785	[735,574]	[1119,1539,1174]	7	hSpCas9	negative selection	5084259
12095622	12095644	17	+	27760321	HT29	viability after 19 days	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	1.055513569258833	[88,69]	[92,59,395]	9	hSpCas9	negative selection	5084260
12107824	12107846	17	-	27760321	HT29	viability after 19 days	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-1.8954545802334763	[21,16]	[13,3,0]	-8	hSpCas9	negative selection	5084261
12110392	12110414	17	-	27760321	HT29	viability after 19 days	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	-2.365478083203529	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	5084262
12110410	12110432	17	+	27760321	HT29	viability after 19 days	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	0.515786414971897	[197,154]	[170,353,326]	5	hSpCas9	negative selection	5084263
12095572	12095594	17	+	27760321	HT29	viability after 16 days	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.5028810184757183	[735,574]	[864,1009,1226]	6	hSpCas9	negative selection	5167722
12095622	12095644	17	+	27760321	HT29	viability after 16 days	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	-0.29991522389890424	[88,69]	[54,41,118]	-3	hSpCas9	negative selection	5167723
12107824	12107846	17	-	27760321	HT29	viability after 16 days	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-1.165444545987154	[21,16]	[6,5,15]	-7	hSpCas9	negative selection	5167724
12110392	12110414	17	-	27760321	HT29	viability after 16 days	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	-2.334013630782607	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	5167725
12110410	12110432	17	+	27760321	HT29	viability after 16 days	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	-0.24163611639765947	[197,154]	[241,97,169]	-3	hSpCas9	negative selection	5167726
12095572	12095594	17	+	27760321	HT29	viability after 13 days	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.2884309462800251	[735,574]	[657,1082,1038]	3	hSpCas9	negative selection	5251185
12095622	12095644	17	+	27760321	HT29	viability after 13 days	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	0.21805941562721665	[88,69]	[151,98,72]	2	hSpCas9	negative selection	5251186
12107824	12107846	17	-	27760321	HT29	viability after 13 days	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.35315646732709016	[21,16]	[1,43,39]	4	hSpCas9	negative selection	5251187
12110392	12110414	17	-	27760321	HT29	viability after 13 days	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	-0.6095761264126871	[4,3]	[0,0,7]	-6	hSpCas9	negative selection	5251188
12110410	12110432	17	+	27760321	HT29	viability after 13 days	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	0.025640925407290238	[197,154]	[137,286,200]	0	hSpCas9	negative selection	5251189
12095572	12095594	17	+	27760321	HT29	viability after 10 days	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.5241573335189272	[735,574]	[1026,1184,1315]	7	hSpCas9	negative selection	5334648
12095622	12095644	17	+	27760321	HT29	viability after 10 days	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	0.38464172108714867	[88,69]	[80,212,97]	5	hSpCas9	negative selection	5334649
12107824	12107846	17	-	27760321	HT29	viability after 10 days	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.6994402942211932	[21,16]	[14,15,13]	-7	hSpCas9	negative selection	5334650
12110392	12110414	17	-	27760321	HT29	viability after 10 days	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	-2.492312337387089	[4,3]	[0,0,0]	-9	hSpCas9	negative selection	5334651
12110410	12110432	17	+	27760321	HT29	viability after 10 days	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	0.09682287380307153	[197,154]	[96,355,256]	1	hSpCas9	negative selection	5334652
12095572	12095594	17	+	27760321	MOLM13	viability	CAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	1.2059043866331987	[919,735]	[1180,977]	8	hSpCas9	negative selection	5418111
12095622	12095644	17	+	27760321	MOLM13	viability	GGATTTGGATGTAGTAATGCGG	MAP2K4	ENSG00000065559	2.3082280901911525	[92,88]	[460,78]	9	hSpCas9	negative selection	5418112
12107824	12107846	17	-	27760321	MOLM13	viability	TTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.4076650233675001	[20,21]	[33,0]	3	hSpCas9	negative selection	5418113
12110392	12110414	17	-	27760321	MOLM13	viability	TTTCAAGTTTTCTTTTAAGTGG	MAP2K4	ENSG00000065559	-1.3619758403181672	[3,4]	[0,0]	-7	hSpCas9	negative selection	5418114
12110410	12110432	17	+	27760321	MOLM13	viability	GAAAATTATTCACAGAGGTGGG	MAP2K4	ENSG00000065559	0.9153613146647405	[203,197]	[135,280]	6	hSpCas9	negative selection	5418115
12021053	12021076	17	+	27661255	K562	viability	GTCGTCGCGGCCTGCCCCAGCGG	MAP2K4	ENSG00000065559	0.17516840424849056	[1090,1128]	[1013,988]	6	dCas9-KRAB	negative selection	5492062
12021067	12021090	17	-	27661255	K562	viability	GGGTCCGGGGGCGTCCGCTGGGG	MAP2K4	ENSG00000065559	0.39353001346574845	[268,359]	[364,296]	9	dCas9-KRAB	negative selection	5492063
12021239	12021262	17	-	27661255	K562	viability	GGCCTGCTGAGAGCCCGGTAGGG	MAP2K4	ENSG00000065559	0.2686604549447393	[466,526]	[453,496]	8	dCas9-KRAB	negative selection	5492064
12021269	12021292	17	-	27661255	K562	viability	GGGGCGGTCCCGGACCAGGTGGG	MAP2K4	ENSG00000065559	-1.929603175111767	[806,832]	[200,146]	-9	dCas9-KRAB	negative selection	5492065
12125306	12125329	17	+	27260156	BXPC3	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.1829661979727666	[1123]	[1142,1459,1335,1410]	4	hSpCas9	negative selection	5554267
12125309	12125332	17	-	27260156	BXPC3	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.051112479615200934	[1297]	[1247,1398,1402,1606]	1	hSpCas9	negative selection	5554268
12113349	12113372	17	-	27260156	BXPC3	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.21826756021394433	[1539]	[1859,1898,1810,1912]	5	hSpCas9	negative selection	5554269
12107824	12107847	17	-	27260156	BXPC3	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.03514550097111058	[175]	[107,176,226,259]	0	hSpCas9	negative selection	5618525
12113323	12113346	17	-	27260156	BXPC3	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	-0.1077324000950135	[299]	[274,311,339,228]	-3	hSpCas9	negative selection	5618526
12054925	12054948	17	+	27260156	BXPC3	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.07613801491628558	[398]	[337,451,523,455]	1	hSpCas9	negative selection	5618527
12125306	12125329	17	+	27260156	A673	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.06329826011035378	[1123]	[1831,1209,1521,1109]	1	hSpCas9	negative selection	5675518
12125309	12125332	17	-	27260156	A673	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.0486345775833561	[1297]	[1439,1499,1747,1745]	1	hSpCas9	negative selection	5675519
12113349	12113372	17	-	27260156	A673	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.35195742232993976	[1539]	[2608,2121,2351,2388]	7	hSpCas9	negative selection	5675520
12107824	12107847	17	-	27260156	A673	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.1301119567029645	[175]	[236,222,284,176]	3	hSpCas9	negative selection	5739776
12113323	12113346	17	-	27260156	A673	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.046692260905943916	[299]	[456,292,396,350]	1	hSpCas9	negative selection	5739777
12054925	12054948	17	+	27260156	A673	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.485748914829314	[398]	[583,683,691,713]	9	hSpCas9	negative selection	5739778
12125306	12125329	17	+	27260156	A375	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.31612834733817796	[1123]	[1682,1973,1555,1394]	4	hSpCas9	negative selection	5796769
12125309	12125332	17	-	27260156	A375	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.17589427855975526	[1297]	[1881,2417,1455,1243]	2	hSpCas9	negative selection	5796770
12113349	12113372	17	-	27260156	A375	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.5204396859569285	[1539]	[2428,3268,2174,2536]	7	hSpCas9	negative selection	5796771
12107824	12107847	17	-	27260156	A375	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.3522419673959032	[175]	[239,307,393,128]	5	hSpCas9	negative selection	5861027
12113323	12113346	17	-	27260156	A375	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.3599341551212413	[299]	[405,436,539,415]	5	hSpCas9	negative selection	5861028
12054925	12054948	17	+	27260156	A375	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.8028327370410852	[398]	[893,911,965,525]	9	hSpCas9	negative selection	5861029
12125306	12125329	17	+	27260156	COLO741	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.1800760775765664	[1123]	[1578,1561,1724]	4	hSpCas9	negative selection	5918020
12125309	12125332	17	-	27260156	COLO741	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.20798369559618823	[1297]	[2421,1801,1585]	4	hSpCas9	negative selection	5918021
12113349	12113372	17	-	27260156	COLO741	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.3866356311512218	[1539]	[3272,2210,2305]	7	hSpCas9	negative selection	5918022
12107824	12107847	17	-	27260156	COLO741	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.5469261579550688	[175]	[261,313,397]	9	hSpCas9	negative selection	5982278
12113323	12113346	17	-	27260156	COLO741	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.40628050253847636	[299]	[389,432,676]	8	hSpCas9	negative selection	5982279
12054925	12054948	17	+	27260156	COLO741	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.5487095948163114	[398]	[708,784,738]	9	hSpCas9	negative selection	5982280
12125306	12125329	17	+	27260156	CAL120	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.38022949344975987	[1123]	[2358,1939,1252]	6	hSpCas9	negative selection	6039271
12125309	12125332	17	-	27260156	CAL120	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.0499262794841302	[1297]	[2108,1331,1325]	0	hSpCas9	negative selection	6039272
12113349	12113372	17	-	27260156	CAL120	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.3493669789700957	[1539]	[2524,2487,2324]	5	hSpCas9	negative selection	6039273
12107824	12107847	17	-	27260156	CAL120	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.05672736212553975	[175]	[294,203,194]	0	hSpCas9	negative selection	6103529
12113323	12113346	17	-	27260156	CAL120	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.01472195256887332	[299]	[262,523,327]	0	hSpCas9	negative selection	6103530
12054925	12054948	17	+	27260156	CAL120	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.3989101154449817	[398]	[599,1009,350]	6	hSpCas9	negative selection	6103531
12125306	12125329	17	+	27260156	CADOES1	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.020842607948653225	[1123]	[1077,908,1117,1139]	0	hSpCas9	negative selection	6160522
12125309	12125332	17	-	27260156	CADOES1	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.03626756475724968	[1297]	[1067,1343,1236,1305]	0	hSpCas9	negative selection	6160523
12113349	12113372	17	-	27260156	CADOES1	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.6229526762601687	[1539]	[2120,2258,1991,2460]	8	hSpCas9	negative selection	6160524
12107824	12107847	17	-	27260156	CADOES1	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.18356160688522705	[175]	[162,285,156,135]	3	hSpCas9	negative selection	6224780
12113323	12113346	17	-	27260156	CADOES1	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.4256803901338031	[299]	[332,386,384,394]	7	hSpCas9	negative selection	6224781
12054925	12054948	17	+	27260156	CADOES1	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.44521166366006526	[398]	[510,511,619,372]	7	hSpCas9	negative selection	6224782
12125306	12125329	17	+	27260156	EWS502	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.01849464113958632	[1123]	[1017,1238,1438,1142]	0	hSpCas9	negative selection	6281773
12125309	12125332	17	-	27260156	EWS502	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.018334733364158362	[1297]	[1234,1225,1445,1552]	0	hSpCas9	negative selection	6281774
12113349	12113372	17	-	27260156	EWS502	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.5620682759895372	[1539]	[2556,2405,2294,2340]	8	hSpCas9	negative selection	6281775
12107824	12107847	17	-	27260156	EWS502	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.1356152756802942	[175]	[222,160,249,182]	2	hSpCas9	negative selection	6346031
12113323	12113346	17	-	27260156	EWS502	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.4748049433587623	[299]	[430,601,397,318]	8	hSpCas9	negative selection	6346032
12054925	12054948	17	+	27260156	EWS502	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.2969017519388196	[398]	[492,454,402,743]	5	hSpCas9	negative selection	6346033
12125306	12125329	17	+	27260156	EW8	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.1647018795207844	[1123]	[1202,783,1032,1077]	3	hSpCas9	negative selection	6403024
12125309	12125332	17	-	27260156	EW8	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.1408496668126642	[1297]	[1095,1280,1090,1172]	2	hSpCas9	negative selection	6403025
12113349	12113372	17	-	27260156	EW8	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.6328904573389289	[1539]	[1950,2256,1759,1800]	9	hSpCas9	negative selection	6403026
12107824	12107847	17	-	27260156	EW8	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.0720510861491146	[175]	[131,178,116,174]	1	hSpCas9	negative selection	6467282
12113323	12113346	17	-	27260156	EW8	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.37968466527770417	[299]	[375,340,227,340]	7	hSpCas9	negative selection	6467283
12054925	12054948	17	+	27260156	EW8	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.4755833006138732	[398]	[493,348,445,512]	8	hSpCas9	negative selection	6467284
12125306	12125329	17	+	27260156	CORL105	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.13636351466627716	[1123]	[1171,1463,1509,1637]	2	hSpCas9	negative selection	6524275
12125309	12125332	17	-	27260156	CORL105	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.06154684450683212	[1297]	[1341,1365,1650,1492]	-1	hSpCas9	negative selection	6524276
12113349	12113372	17	-	27260156	CORL105	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.24936947547962052	[1539]	[2071,2033,2234,2243]	4	hSpCas9	negative selection	6524277
12107824	12107847	17	-	27260156	CORL105	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.20442470002537538	[175]	[206,160,193,156]	-4	hSpCas9	negative selection	6588533
12113323	12113346	17	-	27260156	CORL105	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.40223546264526366	[299]	[420,415,579,456]	7	hSpCas9	negative selection	6588534
12054925	12054948	17	+	27260156	CORL105	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.1869489910102104	[398]	[559,446,455,653]	3	hSpCas9	negative selection	6588535
12125306	12125329	17	+	27260156	HS294T	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.3526759143711635	[1123]	[422,553,502,789]	5	hSpCas9	negative selection	6645526
12125309	12125332	17	-	27260156	HS294T	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.09557524378028637	[1297]	[405,497,647,618]	1	hSpCas9	negative selection	6645527
12113349	12113372	17	-	27260156	HS294T	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.4650528693947471	[1539]	[742,874,689,1014]	6	hSpCas9	negative selection	6645528
12107824	12107847	17	-	27260156	HS294T	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.3289170209145149	[175]	[68,45,47,51]	-5	hSpCas9	negative selection	6709784
12113323	12113346	17	-	27260156	HS294T	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.1268250237655908	[299]	[86,158,115,150]	1	hSpCas9	negative selection	6709785
12054925	12054948	17	+	27260156	HS294T	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.0014233976725011588	[398]	[216,115,106,175]	0	hSpCas9	negative selection	6709786
12125306	12125329	17	+	27260156	HCC44	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.10964846218017499	[1123]	[1425,1353,1371,1331]	1	hSpCas9	negative selection	6766777
12125309	12125332	17	-	27260156	HCC44	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.1014134748710045	[1297]	[1355,994,1766,1461]	-2	hSpCas9	negative selection	6766778
12113349	12113372	17	-	27260156	HCC44	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.2314745468425723	[1539]	[2311,1723,2439,1831]	4	hSpCas9	negative selection	6766779
12107824	12107847	17	-	27260156	HCC44	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.0026475901334730434	[175]	[351,150,194,117]	0	hSpCas9	negative selection	6831035
12113323	12113346	17	-	27260156	HCC44	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	-0.2096101068274866	[299]	[351,176,314,350]	-3	hSpCas9	negative selection	6831036
12054925	12054948	17	+	27260156	HCC44	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.27476061832303345	[398]	[544,434,560,652]	4	hSpCas9	negative selection	6831037
12125306	12125329	17	+	27260156	G402	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.33269793239925827	[1123]	[2193,1654,1316,1795]	4	hSpCas9	negative selection	6888028
12125309	12125332	17	-	27260156	G402	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.018349519298151984	[1297]	[1560,1263,1633,1909]	0	hSpCas9	negative selection	6888029
12113349	12113372	17	-	27260156	G402	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.6987102650716028	[1539]	[3669,2630,3051,2906]	8	hSpCas9	negative selection	6888030
12107824	12107847	17	-	27260156	G402	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.4862892726248045	[175]	[59,273,491,337]	6	hSpCas9	negative selection	6952286
12113323	12113346	17	-	27260156	G402	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.490090418924336	[299]	[742,323,673,343]	6	hSpCas9	negative selection	6952287
12054925	12054948	17	+	27260156	G402	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.9262281899178352	[398]	[695,931,1080,953]	9	hSpCas9	negative selection	6952288
12125306	12125329	17	+	27260156	L33	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.1947157848595662	[1123]	[1310,541,802,1233]	4	hSpCas9	negative selection	7009279
12125309	12125332	17	-	27260156	L33	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.0826019617969338	[1297]	[1252,529,1005,1354]	1	hSpCas9	negative selection	7009280
12113349	12113372	17	-	27260156	L33	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.10281794508442088	[1539]	[1614,687,965,1782]	2	hSpCas9	negative selection	7009281
12107824	12107847	17	-	27260156	L33	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.025140875342665403	[175]	[163,64,119,202]	0	hSpCas9	negative selection	7073537
12113323	12113346	17	-	27260156	L33	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.23643727351732036	[299]	[201,202,194,408]	5	hSpCas9	negative selection	7073538
12054925	12054948	17	+	27260156	L33	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.30531892205304134	[398]	[436,195,269,626]	6	hSpCas9	negative selection	7073539
12125306	12125329	17	+	27260156	K562	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.29409166914844453	[1123]	[910,1161,1287,1467]	3	hSpCas9	negative selection	7130530
12125309	12125332	17	-	27260156	K562	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.47955221211888577	[1297]	[1641,1807,1723,1293]	6	hSpCas9	negative selection	7130531
12113349	12113372	17	-	27260156	K562	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.3831752661281007	[1539]	[1844,2106,1757,1470]	5	hSpCas9	negative selection	7130532
12107824	12107847	17	-	27260156	K562	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.08644659674265442	[175]	[131,232,134,96]	-1	hSpCas9	negative selection	7194788
12113323	12113346	17	-	27260156	K562	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.5049611923469972	[299]	[673,214,368,278]	6	hSpCas9	negative selection	7194789
12054925	12054948	17	+	27260156	K562	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.5832357299187213	[398]	[717,296,286,789]	7	hSpCas9	negative selection	7194790
12125306	12125329	17	+	27260156	HT29	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.12240053013784702	[1123]	[1705,1751,1355,1199]	2	hSpCas9	negative selection	7251781
12125309	12125332	17	-	27260156	HT29	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.07866290088331507	[1297]	[1798,1870,1633,1408]	1	hSpCas9	negative selection	7251782
12113349	12113372	17	-	27260156	HT29	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.4891805964621041	[1539]	[2769,3004,2608,2203]	8	hSpCas9	negative selection	7251783
12107824	12107847	17	-	27260156	HT29	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.39038857451728304	[175]	[244,215,410,243]	7	hSpCas9	negative selection	7316039
12113323	12113346	17	-	27260156	HT29	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.337797326173061	[299]	[558,486,396,412]	6	hSpCas9	negative selection	7316040
12054925	12054948	17	+	27260156	HT29	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.4346650151373155	[398]	[953,611,489,588]	8	hSpCas9	negative selection	7316041
12125306	12125329	17	+	27260156	MHHES1	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.2643112569303918	[1123]	[1679,1801,1633,1082]	5	hSpCas9	negative selection	7373032
12125309	12125332	17	-	27260156	MHHES1	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.26541649054688055	[1297]	[2746,1696,1741,1076]	5	hSpCas9	negative selection	7373033
12113349	12113372	17	-	27260156	MHHES1	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.6040911430584208	[1539]	[2938,3026,2789,1964]	9	hSpCas9	negative selection	7373034
12107824	12107847	17	-	27260156	MHHES1	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.007549427885811255	[175]	[289,142,125,223]	0	hSpCas9	negative selection	7437290
12113323	12113346	17	-	27260156	MHHES1	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.14669617964222648	[299]	[351,551,421,214]	2	hSpCas9	negative selection	7437291
12054925	12054948	17	+	27260156	MHHES1	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.46106293713222934	[398]	[832,642,635,422]	7	hSpCas9	negative selection	7437292
12125306	12125329	17	+	27260156	MEWO	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.03379637226041177	[1123]	[1340,869,931]	0	hSpCas9	negative selection	7494283
12125309	12125332	17	-	27260156	MEWO	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.013458529986064782	[1297]	[1393,1196,1054]	0	hSpCas9	negative selection	7494284
12113349	12113372	17	-	27260156	MEWO	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.2810400728476068	[1539]	[1851,1574,1844]	6	hSpCas9	negative selection	7494285
12107824	12107847	17	-	27260156	MEWO	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.15020719730787935	[175]	[238,77,145]	-3	hSpCas9	negative selection	7558541
12113323	12113346	17	-	27260156	MEWO	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.21267553373907072	[299]	[396,237,354]	4	hSpCas9	negative selection	7558542
12054925	12054948	17	+	27260156	MEWO	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.5239001528879071	[398]	[664,519,449]	9	hSpCas9	negative selection	7558543
12125306	12125329	17	+	27260156	LNCAPCLONEFGC	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.18641433570483845	[1123]	[1118,1098,1074,1332]	3	hSpCas9	negative selection	7615534
12125309	12125332	17	-	27260156	LNCAPCLONEFGC	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.10212782326127035	[1297]	[969,869,1503,1114]	-2	hSpCas9	negative selection	7615535
12113349	12113372	17	-	27260156	LNCAPCLONEFGC	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.4906351425248554	[1539]	[2186,1525,2449,1772]	7	hSpCas9	negative selection	7615536
12107824	12107847	17	-	27260156	LNCAPCLONEFGC	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.1831895467247222	[175]	[119,95,303,228]	3	hSpCas9	negative selection	7679792
12113323	12113346	17	-	27260156	LNCAPCLONEFGC	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.23977032046932933	[299]	[308,221,373,392]	4	hSpCas9	negative selection	7679793
12054925	12054948	17	+	27260156	LNCAPCLONEFGC	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.8353756730929063	[398]	[536,610,822,638]	9	hSpCas9	negative selection	7679794
12125306	12125329	17	+	27260156	PANC0327	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.1495948939065892	[1123]	[1390,1107,1016,936]	2	hSpCas9	negative selection	7736785
12125309	12125332	17	-	27260156	PANC0327	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.39588546646727907	[1297]	[1280,667,791,823]	-5	hSpCas9	negative selection	7736786
12113349	12113372	17	-	27260156	PANC0327	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.43808262037596735	[1539]	[1793,1974,2117,1505]	6	hSpCas9	negative selection	7736787
12107824	12107847	17	-	27260156	PANC0327	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.17184104796751587	[175]	[142,90,340,137]	2	hSpCas9	negative selection	7801043
12113323	12113346	17	-	27260156	PANC0327	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.10128147516642072	[299]	[259,279,275,325]	1	hSpCas9	negative selection	7801044
12054925	12054948	17	+	27260156	PANC0327	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.02567654502650546	[398]	[353,472,306,293]	0	hSpCas9	negative selection	7801045
12125306	12125329	17	+	27260156	NCIH2009	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.5068775457416601	[1123]	[2480,2287,1969]	7	hSpCas9	negative selection	7858036
12125309	12125332	17	-	27260156	NCIH2009	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.2120893205137242	[1297]	[2289,2263,1778]	3	hSpCas9	negative selection	7858037
12113349	12113372	17	-	27260156	NCIH2009	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.2583440048091574	[1539]	[2827,2276,2666]	3	hSpCas9	negative selection	7858038
12107824	12107847	17	-	27260156	NCIH2009	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.030216940778765133	[175]	[209,290,213]	0	hSpCas9	negative selection	7922294
12113323	12113346	17	-	27260156	NCIH2009	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.1347751715493294	[299]	[323,397,631]	1	hSpCas9	negative selection	7922295
12054925	12054948	17	+	27260156	NCIH2009	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.37109662775261	[398]	[853,722,610]	5	hSpCas9	negative selection	7922296
12125306	12125329	17	+	27260156	NCIH1373	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.45273469621170026	[1123]	[2154,1240,1446,577]	4	hSpCas9	negative selection	7979287
12125309	12125332	17	-	27260156	NCIH1373	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.3339364182163851	[1297]	[928,1073,977,429]	-3	hSpCas9	negative selection	7979288
12113349	12113372	17	-	27260156	NCIH1373	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.3825066863183382	[1539]	[2329,2203,1841,699]	4	hSpCas9	negative selection	7979289
12107824	12107847	17	-	27260156	NCIH1373	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.013356799932738417	[175]	[354,134,244,21]	0	hSpCas9	negative selection	8043545
12113323	12113346	17	-	27260156	NCIH1373	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	-0.018920210894083578	[299]	[247,221,298,149]	0	hSpCas9	negative selection	8043546
12054925	12054948	17	+	27260156	NCIH1373	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.2788755716107878	[398]	[972,318,400,149]	2	hSpCas9	negative selection	8043547
12125306	12125329	17	+	27260156	PATU8902	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.3086251336425174	[1123]	[2277,2378,1054,2296]	3	hSpCas9	negative selection	8100538
12125309	12125332	17	-	27260156	PATU8902	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.03889713823552343	[1297]	[2311,1804,1176,2348]	0	hSpCas9	negative selection	8100539
12113349	12113372	17	-	27260156	PATU8902	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.9890413532994542	[1539]	[4300,3716,3855,5352]	9	hSpCas9	negative selection	8100540
12107824	12107847	17	-	27260156	PATU8902	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.293655646534446	[175]	[290,168,320,427]	3	hSpCas9	negative selection	8164796
12113323	12113346	17	-	27260156	PATU8902	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.1321374729803383	[299]	[170,602,553,481]	1	hSpCas9	negative selection	8164797
12054925	12054948	17	+	27260156	PATU8902	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.6303112515012484	[398]	[538,942,753,1279]	6	hSpCas9	negative selection	8164798
12125306	12125329	17	+	27260156	PANC1	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.06854040764742009	[1123]	[943,1228,736,832]	-1	hSpCas9	negative selection	8221789
12125309	12125332	17	-	27260156	PANC1	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.007589551411665063	[1297]	[1177,1210,1187,935]	0	hSpCas9	negative selection	8221790
12113349	12113372	17	-	27260156	PANC1	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.45588988111875683	[1539]	[1586,2758,1577,1544]	7	hSpCas9	negative selection	8221791
12107824	12107847	17	-	27260156	PANC1	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.3575121636291507	[175]	[203,263,221,109]	6	hSpCas9	negative selection	8286047
12113323	12113346	17	-	27260156	PANC1	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	-0.17915171833800358	[299]	[127,249,268,260]	-3	hSpCas9	negative selection	8286048
12054925	12054948	17	+	27260156	PANC1	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	-0.029955864817352157	[398]	[335,435,335,261]	0	hSpCas9	negative selection	8286049
12125306	12125329	17	+	27260156	PANC0813	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.18513868668667355	[1123]	[1526,1314,1642,1518]	3	hSpCas9	negative selection	8343040
12125309	12125332	17	-	27260156	PANC0813	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.1091956827579057	[1297]	[1524,2028,1520,1496]	1	hSpCas9	negative selection	8343041
12113349	12113372	17	-	27260156	PANC0813	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.181871690236578	[1539]	[2450,2073,1807,1914]	3	hSpCas9	negative selection	8343042
12107824	12107847	17	-	27260156	PANC0813	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.44991093187171116	[175]	[217,108,162,122]	-6	hSpCas9	negative selection	8407298
12113323	12113346	17	-	27260156	PANC0813	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.2899328706006566	[299]	[476,475,386,388]	5	hSpCas9	negative selection	8407299
12054925	12054948	17	+	27260156	PANC0813	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.25739893370336997	[398]	[549,524,530,628]	4	hSpCas9	negative selection	8407300
12125306	12125329	17	+	27260156	RDES	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.27957362711752576	[1123]	[1407,1384,1470,2090]	4	hSpCas9	negative selection	8464291
12125309	12125332	17	-	27260156	RDES	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.16526774958267132	[1297]	[1189,1150,1349,1695]	-3	hSpCas9	negative selection	8464292
12113349	12113372	17	-	27260156	RDES	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.5839364438533343	[1539]	[2156,2327,2832,3495]	8	hSpCas9	negative selection	8464293
12107824	12107847	17	-	27260156	RDES	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.6390272127168691	[175]	[253,155,427,470]	8	hSpCas9	negative selection	8528549
12113323	12113346	17	-	27260156	RDES	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.4350456406655556	[299]	[455,459,401,543]	7	hSpCas9	negative selection	8528550
12054925	12054948	17	+	27260156	RDES	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.6159816642803881	[398]	[629,581,670,975]	8	hSpCas9	negative selection	8528551
12125306	12125329	17	+	27260156	PC3	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.07480437480069102	[1123]	[550,1184,2375,1264]	1	hSpCas9	negative selection	8585542
12125309	12125332	17	-	27260156	PC3	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.028788731395821054	[1297]	[968,1164,2219,1289]	0	hSpCas9	negative selection	8585543
12113349	12113372	17	-	27260156	PC3	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.29997224520236654	[1539]	[1238,1598,3473,1980]	6	hSpCas9	negative selection	8585544
12107824	12107847	17	-	27260156	PC3	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.036254688248801514	[175]	[120,230,213,169]	0	hSpCas9	negative selection	8649800
12113323	12113346	17	-	27260156	PC3	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	-0.012448672033625319	[299]	[137,274,580,353]	0	hSpCas9	negative selection	8649801
12054925	12054948	17	+	27260156	PC3	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.4015296520616197	[398]	[479,464,663,495]	8	hSpCas9	negative selection	8649802
12125306	12125329	17	+	27260156	PATU8988T	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.09842859013345473	[1123]	[1115,1212,1160,1165]	1	hSpCas9	negative selection	8706793
12125309	12125332	17	-	27260156	PATU8988T	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.24361353239093142	[1297]	[1269,1810,1407,1481]	4	hSpCas9	negative selection	8706794
12113349	12113372	17	-	27260156	PATU8988T	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.389717765352261	[1539]	[2021,1749,1791,2240]	6	hSpCas9	negative selection	8706795
12107824	12107847	17	-	27260156	PATU8988T	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.21509503210650838	[175]	[401,99,112,163]	3	hSpCas9	negative selection	8771051
12113323	12113346	17	-	27260156	PATU8988T	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.08694631171784561	[299]	[254,335,195,460]	1	hSpCas9	negative selection	8771052
12054925	12054948	17	+	27260156	PATU8988T	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.44656691560934036	[398]	[412,544,629,512]	7	hSpCas9	negative selection	8771053
12125306	12125329	17	+	27260156	T47D	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.18147636925724053	[1123]	[1482,1380,1508,1577]	4	hSpCas9	negative selection	8828044
12125309	12125332	17	-	27260156	T47D	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.03512790835050961	[1297]	[1662,1574,1401,1557]	0	hSpCas9	negative selection	8828045
12113349	12113372	17	-	27260156	T47D	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.3594317618716356	[1539]	[2480,1962,2186,2616]	7	hSpCas9	negative selection	8828046
12107824	12107847	17	-	27260156	T47D	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.36524453020305314	[175]	[258,235,262,301]	7	hSpCas9	negative selection	8892302
12113323	12113346	17	-	27260156	T47D	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.07797798669891132	[299]	[327,326,486,333]	1	hSpCas9	negative selection	8892303
12054925	12054948	17	+	27260156	T47D	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.5020679992478932	[398]	[678,643,600,712]	9	hSpCas9	negative selection	8892304
12125306	12125329	17	+	27260156	SU8686	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.364220758511953	[1123]	[1345,1390,1372,1668]	6	hSpCas9	negative selection	8949295
12125309	12125332	17	-	27260156	SU8686	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.04357493715875438	[1297]	[1244,1060,1235,1509]	-1	hSpCas9	negative selection	8949296
12113349	12113372	17	-	27260156	SU8686	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.07404911705769623	[1539]	[1519,1393,1475,2148]	1	hSpCas9	negative selection	8949297
12107824	12107847	17	-	27260156	SU8686	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.022812092663885952	[175]	[136,130,307,139]	0	hSpCas9	negative selection	9013553
12113323	12113346	17	-	27260156	SU8686	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	-0.02377294150444531	[299]	[333,243,316,271]	0	hSpCas9	negative selection	9013554
12054925	12054948	17	+	27260156	SU8686	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.2804601190390863	[398]	[479,539,379,512]	5	hSpCas9	negative selection	9013555
12125306	12125329	17	+	27260156	SKES1	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.08499550682867696	[1123]	[1252,1188,1277,1048]	1	hSpCas9	negative selection	9070546
12125309	12125332	17	-	27260156	SKES1	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.19827154021526172	[1297]	[1346,1200,1110,908]	-4	hSpCas9	negative selection	9070547
12113349	12113372	17	-	27260156	SKES1	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.2554031921534148	[1539]	[1975,1954,1796,1644]	5	hSpCas9	negative selection	9070548
12107824	12107847	17	-	27260156	SKES1	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.40164220333123146	[175]	[187,221,354,159]	8	hSpCas9	negative selection	9134804
12113323	12113346	17	-	27260156	SKES1	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.3087682075161178	[299]	[509,370,395,236]	6	hSpCas9	negative selection	9134805
12054925	12054948	17	+	27260156	SKES1	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.40932673175016343	[398]	[720,468,620,338]	8	hSpCas9	negative selection	9134806
12125306	12125329	17	+	27260156	TOV112D	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.11287262678224153	[1123]	[1512,1211,1166,1004]	2	hSpCas9	negative selection	9191797
12125309	12125332	17	-	27260156	TOV112D	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.27949170086481967	[1297]	[1102,1431,1022,822]	-5	hSpCas9	negative selection	9191798
12113349	12113372	17	-	27260156	TOV112D	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.17260559108951812	[1539]	[1849,2151,1540,1524]	3	hSpCas9	negative selection	9191799
12107824	12107847	17	-	27260156	TOV112D	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	-0.059060319552675766	[175]	[199,168,101,206]	-1	hSpCas9	negative selection	9256055
12113323	12113346	17	-	27260156	TOV112D	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.1049880507722748	[299]	[402,453,187,286]	2	hSpCas9	negative selection	9256056
12054925	12054948	17	+	27260156	TOV112D	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.4695734406611819	[398]	[648,768,424,433]	8	hSpCas9	negative selection	9256057
12125306	12125329	17	+	27260156	TC71	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.029596535832633775	[1123]	[1180,1248,1242,1247]	0	hSpCas9	negative selection	9313048
12125309	12125332	17	-	27260156	TC71	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	-0.1499793642347662	[1297]	[1326,1210,1195,1283]	-4	hSpCas9	negative selection	9313049
12113349	12113372	17	-	27260156	TC71	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.384834671127426	[1539]	[2119,2385,1803,2334]	8	hSpCas9	negative selection	9313050
12107824	12107847	17	-	27260156	TC71	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.20958303819002144	[175]	[170,194,330,169]	5	hSpCas9	negative selection	9377306
12113323	12113346	17	-	27260156	TC71	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	-0.03219453458007426	[299]	[235,333,310,382]	-1	hSpCas9	negative selection	9377307
12054925	12054948	17	+	27260156	TC71	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.4835263850861026	[398]	[540,592,690,562]	9	hSpCas9	negative selection	9377308
12125306	12125329	17	+	27260156	TC32	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.2866245837635508	[1123]	[1251,1150,1403,1343]	5	hSpCas9	negative selection	9434299
12125309	12125332	17	-	27260156	TC32	viability	TATCCTTGTCGTGATGCGCTTGG	MAP2K4	ENSG00000065559	0.116781838944918	[1297]	[1143,1029,1686,1560]	2	hSpCas9	negative selection	9434300
12113349	12113372	17	-	27260156	TC32	viability	TTAACACTTACTGCCATGTATGG	MAP2K4	ENSG00000065559	0.5807698450929386	[1539]	[1982,1636,2690,2553]	8	hSpCas9	negative selection	9434301
12107824	12107847	17	-	27260156	TC32	viability	TTTGTAAAACTTATCAAACGAGG	MAP2K4	ENSG00000065559	0.4881991193242202	[175]	[163,205,364,219]	8	hSpCas9	negative selection	9498557
12113323	12113346	17	-	27260156	TC32	viability	ACAGCCAGCATCTCTTGTCTTGG	MAP2K4	ENSG00000065559	0.5662671109326547	[299]	[362,317,505,523]	8	hSpCas9	negative selection	9498558
12054925	12054948	17	+	27260156	TC32	viability	CACCTTTCAAATCTACAGCAAGG	MAP2K4	ENSG00000065559	0.47304703832795303	[398]	[379,443,652,650]	7	hSpCas9	negative selection	9498559
12095571	12095594	17	+	27869803	HPAFII	viability after 27 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.5316517780445642	[724]	[730,400,NaN]	4	hSpCas9	negative selection	9559145
12095673	12095696	17	+	27869803	HPAFII	viability after 27 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.8883692975841768	[355]	[280,400,NaN]	7	hSpCas9	negative selection	9559146
12125306	12125329	17	+	27869803	HPAFII	viability after 27 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.4413991891784494	[312]	[265,187,NaN]	3	hSpCas9	negative selection	9559147
12129133	12129156	17	+	27869803	HPAFII	viability after 27 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	1.1996599998125042	[105]	[61,182,NaN]	8	hSpCas9	negative selection	9559148
12141235	12141258	17	-	27869803	HPAFII	viability after 27 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	0.6508021420236406	[162]	[139,129,NaN]	5	hSpCas9	negative selection	9559149
12095571	12095594	17	+	27869803	HPAFII	viability after 15 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.542970503786216	[724]	[1556,872,NaN]	6	hSpCas9	negative selection	9641594
12095673	12095696	17	+	27869803	HPAFII	viability after 15 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.42394676297894807	[355]	[672,413,NaN]	5	hSpCas9	negative selection	9641595
12125306	12125329	17	+	27869803	HPAFII	viability after 15 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.04926592966262877	[312]	[469,234,NaN]	0	hSpCas9	negative selection	9641596
12129133	12129156	17	+	27869803	HPAFII	viability after 15 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	0.9785406442259883	[105]	[176,253,NaN]	9	hSpCas9	negative selection	9641597
12141235	12141258	17	-	27869803	HPAFII	viability after 15 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	-0.6408257051629537	[162]	[128,101,NaN]	-6	hSpCas9	negative selection	9641598
12095571	12095594	17	+	27869803	ASPC1	viability after 36 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.029516127805107262	[2266]	[923,851,601]	0	hSpCas9	negative selection	9724043
12095673	12095696	17	+	27869803	ASPC1	viability after 36 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	-0.15359129052523823	[1184]	[287,450,363]	-1	hSpCas9	negative selection	9724044
12125306	12125329	17	+	27869803	ASPC1	viability after 36 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.20764073062645583	[772]	[598,280,130]	2	hSpCas9	negative selection	9724045
12129133	12129156	17	+	27869803	ASPC1	viability after 36 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	0.43671459432678006	[251]	[242,99,45]	4	hSpCas9	negative selection	9724046
12141235	12141258	17	-	27869803	ASPC1	viability after 36 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	1.2470349409275294	[247]	[161,9,388]	9	hSpCas9	negative selection	9724047
12095571	12095594	17	+	27869803	PATU8988S	viability after 35 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.03313951813418603	[2087]	[852,867,NaN]	0	hSpCas9	negative selection	9806492
12095673	12095696	17	+	27869803	PATU8988S	viability after 35 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.02625123210481961	[944]	[425,348,NaN]	0	hSpCas9	negative selection	9806493
12125306	12125329	17	+	27869803	PATU8988S	viability after 35 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.39188517714413795	[693]	[222,202,NaN]	-4	hSpCas9	negative selection	9806494
12129133	12129156	17	+	27869803	PATU8988S	viability after 35 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-1.2152520361786596	[371]	[76,51,NaN]	-8	hSpCas9	negative selection	9806495
12141235	12141258	17	-	27869803	PATU8988S	viability after 35 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	0.7606287035475415	[191]	[135,125,NaN]	7	hSpCas9	negative selection	9806496
12095571	12095594	17	+	27869803	PATU8988S	viability after 31 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.25974143002793837	[2087]	[496,947,NaN]	-3	hSpCas9	negative selection	9888941
12095673	12095696	17	+	27869803	PATU8988S	viability after 31 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.19050473774533083	[944]	[451,401,NaN]	2	hSpCas9	negative selection	9888942
12125306	12125329	17	+	27869803	PATU8988S	viability after 31 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.4520902054543016	[693]	[218,180,NaN]	-5	hSpCas9	negative selection	9888943
12129133	12129156	17	+	27869803	PATU8988S	viability after 31 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	-0.8728820052069628	[371]	[69,94,NaN]	-7	hSpCas9	negative selection	9888944
12141235	12141258	17	-	27869803	PATU8988S	viability after 31 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	0.24613228887944127	[191]	[92,87,NaN]	3	hSpCas9	negative selection	9888945
12095571	12095594	17	+	27869803	HPAFII	viability after 35 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.5194955499318177	[724]	[646,389,NaN]	3	hSpCas9	negative selection	9971390
12095673	12095696	17	+	27869803	HPAFII	viability after 35 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.9450155022910527	[355]	[282,418,NaN]	6	hSpCas9	negative selection	9971391
12125306	12125329	17	+	27869803	HPAFII	viability after 35 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.8598150801981586	[312]	[359,205,NaN]	5	hSpCas9	negative selection	9971392
12129133	12129156	17	+	27869803	HPAFII	viability after 35 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	1.7148951243957427	[105]	[19,351,NaN]	9	hSpCas9	negative selection	9971393
12141235	12141258	17	-	27869803	HPAFII	viability after 35 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	-0.32112272833779265	[162]	[50,82,NaN]	-2	hSpCas9	negative selection	9971394
12095571	12095594	17	+	27869803	HPAFII	viability after 31 days	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.629842112778922	[724]	[698,553,NaN]	4	hSpCas9	negative selection	10053839
12095673	12095696	17	+	27869803	HPAFII	viability after 31 days	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.6850620962408962	[355]	[314,327,NaN]	5	hSpCas9	negative selection	10053840
12125306	12125329	17	+	27869803	HPAFII	viability after 31 days	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.3946552228111205	[312]	[273,183,NaN]	3	hSpCas9	negative selection	10053841
12129133	12129156	17	+	27869803	HPAFII	viability after 31 days	CTTTAGTATGAGTTGGCCACAGG	MAP2K4	ENSG00000065559	1.5165379719106586	[105]	[62,286,NaN]	9	hSpCas9	negative selection	10053842
12141235	12141258	17	-	27869803	HPAFII	viability after 31 days	ATCGACATACATGGGAGAGCTGG	MAP2K4	ENSG00000065559	0.3199716469804044	[162]	[84,145,NaN]	2	hSpCas9	negative selection	10053843
12095571	12095594	17	+	28162770	P31FUJ	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.3596548328537017	[511]	[771]	4	hSpCas9	negative selection	10188677
12113319	12113342	17	+	28162770	P31FUJ	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.2871604495031428	[854]	[1225]	3	hSpCas9	negative selection	10188678
12129257	12129280	17	-	28162770	P31FUJ	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	-0.30459288748238866	[205]	[195]	-3	hSpCas9	negative selection	10188679
12020976	12020999	17	-	28162770	P31FUJ	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.9066478386875868	[201]	[444]	9	hSpCas9	negative selection	10188680
12081447	12081470	17	+	28162770	P31FUJ	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	-0.2152081443996403	[162]	[164]	-2	hSpCas9	negative selection	10188681
12125306	12125329	17	+	28162770	P31FUJ	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.04422449607017443	[221]	[252]	0	hSpCas9	negative selection	10188682
12125338	12125361	17	-	28162770	P31FUJ	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	0.7146144639860534	[460]	[888]	7	hSpCas9	negative selection	10188683
12020887	12020910	17	+	28162770	P31FUJ	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.3216733747753986	[270]	[397]	3	hSpCas9	negative selection	10188684
12129149	12129172	17	-	28162770	P31FUJ	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	0.36462041729524425	[268]	[406]	4	hSpCas9	negative selection	10188685
12095673	12095696	17	+	28162770	P31FUJ	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.38304280258003454	[1062]	[1628]	4	hSpCas9	negative selection	10188686
12095571	12095594	17	+	28162770	TF1	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	NaN	[NaN]	[379]	1	hSpCas9	negative selection	10358043
12113319	12113342	17	+	28162770	TF1	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	NaN	[NaN]	[634]	1	hSpCas9	negative selection	10358044
12129257	12129280	17	-	28162770	TF1	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10358045
12020976	12020999	17	-	28162770	TF1	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	NaN	[NaN]	[174]	1	hSpCas9	negative selection	10358046
12081447	12081470	17	+	28162770	TF1	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10358047
12125306	12125329	17	+	28162770	TF1	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	NaN	[NaN]	[178]	1	hSpCas9	negative selection	10358048
12125338	12125361	17	-	28162770	TF1	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	NaN	[NaN]	[588]	1	hSpCas9	negative selection	10358049
12020887	12020910	17	+	28162770	TF1	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	NaN	[NaN]	[178]	1	hSpCas9	negative selection	10358050
12129149	12129172	17	-	28162770	TF1	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	NaN	[NaN]	[228]	1	hSpCas9	negative selection	10358051
12095673	12095696	17	+	28162770	TF1	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	NaN	[NaN]	[1012]	1	hSpCas9	negative selection	10358052
12095571	12095594	17	+	28162770	SKM1	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.3788173113660904	[153]	[353]	3	hSpCas9	negative selection	10527409
12113319	12113342	17	+	28162770	SKM1	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.3329341292008534	[171]	[382]	3	hSpCas9	negative selection	10527410
12129257	12129280	17	-	28162770	SKM1	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	0.24511249783653138	[62]	[131]	2	hSpCas9	negative selection	10527411
12020976	12020999	17	-	28162770	SKM1	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.8801984779835239	[62]	[204]	8	hSpCas9	negative selection	10527412
12081447	12081470	17	+	28162770	SKM1	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	-0.07949792031436943	[51]	[86]	0	hSpCas9	negative selection	10527413
12125306	12125329	17	+	28162770	SKM1	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.3083949392336695	[73]	[161]	3	hSpCas9	negative selection	10527414
12125338	12125361	17	-	28162770	SKM1	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	0.40221345892126004	[112]	[263]	4	hSpCas9	negative selection	10527415
12020887	12020910	17	+	28162770	SKM1	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.020457024991514472	[86]	[155]	0	hSpCas9	negative selection	10527416
12129149	12129172	17	-	28162770	SKM1	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	1.1054858021936265	[50]	[193]	8	hSpCas9	negative selection	10527417
12095673	12095696	17	+	28162770	SKM1	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.8248885518423528	[189]	[594]	7	hSpCas9	negative selection	10527418
12095571	12095594	17	+	28162770	SKM1	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.3788173113660904	[153]	[353]	3	hSpCas9	negative selection	10696775
12113319	12113342	17	+	28162770	SKM1	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.3329341292008534	[171]	[382]	3	hSpCas9	negative selection	10696776
12129257	12129280	17	-	28162770	SKM1	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	0.24511249783653138	[62]	[131]	2	hSpCas9	negative selection	10696777
12020976	12020999	17	-	28162770	SKM1	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.8801984779835239	[62]	[204]	8	hSpCas9	negative selection	10696778
12081447	12081470	17	+	28162770	SKM1	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	-0.07949792031436943	[51]	[86]	0	hSpCas9	negative selection	10696779
12125306	12125329	17	+	28162770	SKM1	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.3083949392336695	[73]	[161]	3	hSpCas9	negative selection	10696780
12125338	12125361	17	-	28162770	SKM1	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	0.40221345892126004	[112]	[263]	4	hSpCas9	negative selection	10696781
12020887	12020910	17	+	28162770	SKM1	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.020457024991514472	[86]	[155]	0	hSpCas9	negative selection	10696782
12129149	12129172	17	-	28162770	SKM1	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	1.1054858021936265	[50]	[193]	8	hSpCas9	negative selection	10696783
12095673	12095696	17	+	28162770	SKM1	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.8248885518423528	[189]	[594]	7	hSpCas9	negative selection	10696784
12095571	12095594	17	+	28162770	PL21	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.6125516443613406	[549]	[365]	5	hSpCas9	negative selection	10866141
12113319	12113342	17	+	28162770	PL21	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.09704612152521652	[579]	[269]	0	hSpCas9	negative selection	10866142
12129257	12129280	17	-	28162770	PL21	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	-0.41601750783543034	[186]	[60]	-3	hSpCas9	negative selection	10866143
12020976	12020999	17	-	28162770	PL21	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.9767614090073166	[243]	[208]	7	hSpCas9	negative selection	10866144
12081447	12081470	17	+	28162770	PL21	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.011105790099303237	[113]	[49]	0	hSpCas9	negative selection	10866145
12125306	12125329	17	+	28162770	PL21	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.516262087695477	[248]	[154]	4	hSpCas9	negative selection	10866146
12125338	12125361	17	-	28162770	PL21	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	0.1104094538333078	[397]	[186]	1	hSpCas9	negative selection	10866147
12020887	12020910	17	+	28162770	PL21	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.774375708617418	[179]	[133]	6	hSpCas9	negative selection	10866148
12129149	12129172	17	-	28162770	PL21	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	0.026310158591091704	[184]	[81]	0	hSpCas9	negative selection	10866149
12095673	12095696	17	+	28162770	PL21	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.9441501234471112	[571]	[478]	7	hSpCas9	negative selection	10866150
12095571	12095594	17	+	28162770	P31FUJ	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.3596548328537017	[511]	[771]	4	hSpCas9	negative selection	11035507
12113319	12113342	17	+	28162770	P31FUJ	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.2871604495031428	[854]	[1225]	3	hSpCas9	negative selection	11035508
12129257	12129280	17	-	28162770	P31FUJ	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	-0.30459288748238866	[205]	[195]	-3	hSpCas9	negative selection	11035509
12020976	12020999	17	-	28162770	P31FUJ	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.9066478386875868	[201]	[444]	9	hSpCas9	negative selection	11035510
12081447	12081470	17	+	28162770	P31FUJ	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	-0.2152081443996403	[162]	[164]	-2	hSpCas9	negative selection	11035511
12125306	12125329	17	+	28162770	P31FUJ	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.04422449607017443	[221]	[252]	0	hSpCas9	negative selection	11035512
12125338	12125361	17	-	28162770	P31FUJ	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	0.7146144639860534	[460]	[888]	7	hSpCas9	negative selection	11035513
12020887	12020910	17	+	28162770	P31FUJ	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.3216733747753986	[270]	[397]	3	hSpCas9	negative selection	11035514
12129149	12129172	17	-	28162770	P31FUJ	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	0.36462041729524425	[268]	[406]	4	hSpCas9	negative selection	11035515
12095673	12095696	17	+	28162770	P31FUJ	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.38304280258003454	[1062]	[1628]	4	hSpCas9	negative selection	11035516
12095571	12095594	17	+	28162770	OCIAML5	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.45089812005077023	[290]	[717]	4	hSpCas9	negative selection	11204873
12113319	12113342	17	+	28162770	OCIAML5	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.6190760302999969	[434]	[1205]	5	hSpCas9	negative selection	11204874
12129257	12129280	17	-	28162770	OCIAML5	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	1.2507442347197784	[87]	[377]	9	hSpCas9	negative selection	11204875
12020976	12020999	17	-	28162770	OCIAML5	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.4266494572020667	[121]	[295]	3	hSpCas9	negative selection	11204876
12081447	12081470	17	+	28162770	OCIAML5	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.8084469628643358	[30]	[97]	7	hSpCas9	negative selection	11204877
12125306	12125329	17	+	28162770	OCIAML5	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.004069664309046872	[169]	[305]	0	hSpCas9	negative selection	11204878
12125338	12125361	17	-	28162770	OCIAML5	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	0.5272792212715378	[265]	[691]	4	hSpCas9	negative selection	11204879
12020887	12020910	17	+	28162770	OCIAML5	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.29006627855699185	[197]	[436]	2	hSpCas9	negative selection	11204880
12129149	12129172	17	-	28162770	OCIAML5	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	0.8665743650891287	[102]	[338]	7	hSpCas9	negative selection	11204881
12095673	12095696	17	+	28162770	OCIAML5	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.7022805626190749	[507]	[1491]	6	hSpCas9	negative selection	11204882
12095571	12095594	17	+	28162770	EOL1	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	-0.13625550749166537	[944]	[452]	-1	hSpCas9	negative selection	11374239
12113319	12113342	17	+	28162770	EOL1	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.4440095286507759	[765]	[548]	4	hSpCas9	negative selection	11374240
12129257	12129280	17	-	28162770	EOL1	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	0.9668585764284989	[335]	[345]	8	hSpCas9	negative selection	11374241
12020976	12020999	17	-	28162770	EOL1	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.8789509051304237	[449]	[435]	7	hSpCas9	negative selection	11374242
12081447	12081470	17	+	28162770	EOL1	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.5886804857252984	[259]	[205]	5	hSpCas9	negative selection	11374243
12125306	12125329	17	+	28162770	EOL1	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.07210495998439237	[389]	[215]	0	hSpCas9	negative selection	11374244
12125338	12125361	17	-	28162770	EOL1	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	-0.02865801695052439	[454]	[234]	0	hSpCas9	negative selection	11374245
12020887	12020910	17	+	28162770	EOL1	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.9928170475875633	[226]	[237]	8	hSpCas9	negative selection	11374246
12129149	12129172	17	-	28162770	EOL1	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	1.7502422843310723	[267]	[474]	9	hSpCas9	negative selection	11374247
12095673	12095696	17	+	28162770	EOL1	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.9488463676939316	[941]	[957]	7	hSpCas9	negative selection	11374248
12095571	12095594	17	+	28162770	MOLM13	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.17354890653283217	[763]	[622]	1	hSpCas9	negative selection	11543605
12113319	12113342	17	+	28162770	MOLM13	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	-0.16630063394723882	[938]	[604]	-1	hSpCas9	negative selection	11543606
12129257	12129280	17	-	28162770	MOLM13	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	1.0513146471273371	[312]	[468]	7	hSpCas9	negative selection	11543607
12020976	12020999	17	-	28162770	MOLM13	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.7790293700616515	[348]	[432]	6	hSpCas9	negative selection	11543608
12081447	12081470	17	+	28162770	MOLM13	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.15040719168840863	[242]	[194]	1	hSpCas9	negative selection	11543609
12125306	12125329	17	+	28162770	MOLM13	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.4950742108708093	[367]	[374]	3	hSpCas9	negative selection	11543610
12125338	12125361	17	-	28162770	MOLM13	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	0.23907069104869771	[674]	[575]	1	hSpCas9	negative selection	11543611
12020887	12020910	17	+	28162770	MOLM13	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	1.5020843014281755	[270]	[554]	9	hSpCas9	negative selection	11543612
12129149	12129172	17	-	28162770	MOLM13	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	1.2421222334274744	[213]	[365]	8	hSpCas9	negative selection	11543613
12095673	12095696	17	+	28162770	MOLM13	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.4378815063139925	[922]	[903]	3	hSpCas9	negative selection	11543614
12095571	12095594	17	+	28162770	HEL	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.6583991761723791	[732]	[740]	5	hSpCas9	negative selection	11712971
12113319	12113342	17	+	28162770	HEL	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.6316154535286462	[650]	[645]	5	hSpCas9	negative selection	11712972
12129257	12129280	17	-	28162770	HEL	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	0.5245574056520429	[266]	[245]	4	hSpCas9	negative selection	11712973
12020976	12020999	17	-	28162770	HEL	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	1.7184385581322097	[296]	[625]	9	hSpCas9	negative selection	11712974
12081447	12081470	17	+	28162770	HEL	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.9143352513375749	[139]	[168]	7	hSpCas9	negative selection	11712975
12125306	12125329	17	+	28162770	HEL	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	1.0835855176288058	[276]	[375]	8	hSpCas9	negative selection	11712976
12125338	12125361	17	-	28162770	HEL	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	-0.6920133032445892	[564]	[223]	-4	hSpCas9	negative selection	11712977
12020887	12020910	17	+	28162770	HEL	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.686682179587954	[193]	[199]	6	hSpCas9	negative selection	11712978
12129149	12129172	17	-	28162770	HEL	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	1.374249996074455	[158]	[263]	9	hSpCas9	negative selection	11712979
12095673	12095696	17	+	28162770	HEL	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.07980263760919981	[779]	[527]	0	hSpCas9	negative selection	11712980
12095571	12095594	17	+	28162770	MV411	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.508635298136952	[523]	[627]	4	hSpCas9	negative selection	11882337
12113319	12113342	17	+	28162770	MV411	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.7729957643063359	[470]	[677]	7	hSpCas9	negative selection	11882338
12129257	12129280	17	-	28162770	MV411	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	0.09623174668705195	[200]	[180]	0	hSpCas9	negative selection	11882339
12020976	12020999	17	-	28162770	MV411	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.3570620419572736	[227]	[245]	3	hSpCas9	negative selection	11882340
12081447	12081470	17	+	28162770	MV411	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.008650691195658755	[117]	[99]	0	hSpCas9	negative selection	11882341
12125306	12125329	17	+	28162770	MV411	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.7374371077428412	[224]	[315]	6	hSpCas9	negative selection	11882342
12125338	12125361	17	-	28162770	MV411	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	-0.16258187372944394	[286]	[215]	-1	hSpCas9	negative selection	11882343
12020887	12020910	17	+	28162770	MV411	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.715089676225041	[174]	[241]	6	hSpCas9	negative selection	11882344
12129149	12129172	17	-	28162770	MV411	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	0.6831740427294554	[172]	[233]	6	hSpCas9	negative selection	11882345
12095673	12095696	17	+	28162770	MV411	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.37868208406102766	[713]	[781]	3	hSpCas9	negative selection	11882346
12095571	12095594	17	+	28162770	MONOMAC1	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.2062147378415795	[337]	[446]	2	hSpCas9	negative selection	12051703
12113319	12113342	17	+	28162770	MONOMAC1	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.011126137972754746	[392]	[453]	0	hSpCas9	negative selection	12051704
12129257	12129280	17	-	28162770	MONOMAC1	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	0.5185946054277762	[108]	[178]	5	hSpCas9	negative selection	12051705
12020976	12020999	17	-	28162770	MONOMAC1	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	-0.4240019981858258	[157]	[134]	-4	hSpCas9	negative selection	12051706
12081447	12081470	17	+	28162770	MONOMAC1	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.0768858749169764	[109]	[132]	0	hSpCas9	negative selection	12051707
12125306	12125329	17	+	28162770	MONOMAC1	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.15541611484126716	[158]	[202]	1	hSpCas9	negative selection	12051708
12125338	12125361	17	-	28162770	MONOMAC1	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	0.8242317696940976	[201]	[409]	7	hSpCas9	negative selection	12051709
12020887	12020910	17	+	28162770	MONOMAC1	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.8489755506972825	[107]	[222]	7	hSpCas9	negative selection	12051710
12129149	12129172	17	-	28162770	MONOMAC1	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	-0.2111120322712764	[102]	[101]	-2	hSpCas9	negative selection	12051711
12095673	12095696	17	+	28162770	MONOMAC1	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.6745574209364009	[410]	[751]	6	hSpCas9	negative selection	12051712
12095571	12095594	17	+	28162770	OCIAML2	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.41462229107816584	[102]	[760]	4	hSpCas9	negative selection	12221069
12113319	12113342	17	+	28162770	OCIAML2	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	0.5421942151154224	[97]	[790]	5	hSpCas9	negative selection	12221070
12129257	12129280	17	-	28162770	OCIAML2	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	0.4811150061506177	[37]	[293]	4	hSpCas9	negative selection	12221071
12020976	12020999	17	-	28162770	OCIAML2	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.30259931291081654	[54]	[375]	3	hSpCas9	negative selection	12221072
12081447	12081470	17	+	28162770	OCIAML2	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	0.2383213927544483	[25]	[169]	2	hSpCas9	negative selection	12221073
12125306	12125329	17	+	28162770	OCIAML2	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	0.4528914449104781	[45]	[348]	4	hSpCas9	negative selection	12221074
12125338	12125361	17	-	28162770	OCIAML2	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	0.46523983733812313	[68]	[527]	4	hSpCas9	negative selection	12221075
12020887	12020910	17	+	28162770	OCIAML2	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.027275941209771642	[36]	[208]	0	hSpCas9	negative selection	12221076
12129149	12129172	17	-	28162770	OCIAML2	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	0.490199577477161	[27]	[217]	5	hSpCas9	negative selection	12221077
12095673	12095696	17	+	28162770	OCIAML2	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	0.46211042120953616	[117]	[900]	4	hSpCas9	negative selection	12221078
12095571	12095594	17	+	28162770	OCIAML3	viability	CCAGAGAATTCGGTCAACAGTGG	MAP2K4	ENSG00000065559	0.02636019652819188	[160]	[494]	0	hSpCas9	negative selection	12390435
12113319	12113342	17	+	28162770	OCIAML3	viability	ATTGCCAAGACAAGAGATGCTGG	MAP2K4	ENSG00000065559	-0.4609822216933799	[175]	[385]	-4	hSpCas9	negative selection	12390436
12129257	12129280	17	-	28162770	OCIAML3	viability	GACAAAGTTGATGAAACTCGGGG	MAP2K4	ENSG00000065559	0.27798474729976524	[52]	[193]	2	hSpCas9	negative selection	12390437
12020976	12020999	17	-	28162770	OCIAML3	viability	GCATGCTGCTGACGGCCGGGTGG	MAP2K4	ENSG00000065559	0.48323535860829736	[49]	[210]	4	hSpCas9	negative selection	12390438
12081447	12081470	17	+	28162770	OCIAML3	viability	GACCTTGGAGAAATTGGACGAGG	MAP2K4	ENSG00000065559	-0.09650798085334633	[33]	[95]	0	hSpCas9	negative selection	12390439
12125306	12125329	17	+	28162770	OCIAML3	viability	GACCCAAGCGCATCACGACAAGG	MAP2K4	ENSG00000065559	-0.10656164551726928	[50]	[142]	-1	hSpCas9	negative selection	12390440
12125338	12125361	17	-	28162770	OCIAML3	viability	CCAAACTCCAGACATCAGAGCGG	MAP2K4	ENSG00000065559	-0.1961846963975189	[136]	[360]	-1	hSpCas9	negative selection	12390441
12020887	12020910	17	+	28162770	OCIAML3	viability	ATGGCGGCTCCGAGCCCGAGCGG	MAP2K4	ENSG00000065559	0.7922708659732567	[56]	[297]	7	hSpCas9	negative selection	12390442
12129149	12129172	17	-	28162770	OCIAML3	viability	TGGATAAGGAAATCGGCCTGTGG	MAP2K4	ENSG00000065559	1.0689573723982662	[41]	[265]	8	hSpCas9	negative selection	12390443
12095673	12095696	17	+	28162770	OCIAML3	viability	TTATGGTGCACTCTTCAGAGAGG	MAP2K4	ENSG00000065559	1.2845542322258605	[191]	[1411]	9	hSpCas9	negative selection	12390444