Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5607
• Symbol:MAP2K5
• Description:mitogen-activated protein kinase kinase 5

DataSource: http://genomecrispr.dkfz.de/#!/results/MAP2K5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
67703333	67703356	15	+	26472758	Jiyoye	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	0.7586477520072512	[115]	[147]	5	hSpCas9	negative selection	95916
67692498	67692521	15	+	26472758	Jiyoye	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-0.7221076354390932	[34]	[15]	-5	hSpCas9	negative selection	95917
67563314	67563337	15	+	26472758	Jiyoye	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	-0.11532303226862939	[338]	[235]	-1	hSpCas9	negative selection	95918
67580761	67580784	15	-	26472758	Jiyoye	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.1211588054223629	[366]	[300]	0	hSpCas9	negative selection	95919
67580802	67580825	15	+	26472758	Jiyoye	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.6966819987008583	[152]	[186]	5	hSpCas9	negative selection	95920
67600712	67600735	15	+	26472758	Jiyoye	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	0.2593299135344793	[307]	[277]	2	hSpCas9	negative selection	95921
67769602	67769625	15	+	26472758	Jiyoye	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	-0.5500749710347895	[265]	[136]	-4	hSpCas9	negative selection	95922
67769609	67769632	15	-	26472758	Jiyoye	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	-1.9752942553165398	[72]	[13]	-8	hSpCas9	negative selection	95923
67585909	67585932	15	+	26472758	Jiyoye	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	0.44132360391771897	[166]	[170]	3	hSpCas9	negative selection	95924
67630886	67630909	15	+	26472758	Jiyoye	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	-0.40821685961714893	[314]	[178]	-3	hSpCas9	negative selection	95925
67703333	67703356	15	+	26472758	KBM7	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	-0.6885580371839367	[621,296]	[141,118]	-5	hSpCas9	negative selection	287034
67692498	67692521	15	+	26472758	KBM7	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-0.3305607948344098	[217,183]	[48,97]	-3	hSpCas9	negative selection	287035
67563314	67563337	15	+	26472758	KBM7	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	-0.12801435821875762	[1643,992]	[673,449]	-1	hSpCas9	negative selection	287036
67580761	67580784	15	-	26472758	KBM7	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.10687658672128597	[1423,1161]	[505,610]	-1	hSpCas9	negative selection	287037
67580802	67580825	15	+	26472758	KBM7	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.3518574622257591	[1035,594]	[568,396]	4	hSpCas9	negative selection	287038
67600712	67600735	15	+	26472758	KBM7	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	0.08530752720491219	[1187,1177]	[578,604]	0	hSpCas9	negative selection	287039
67769602	67769625	15	+	26472758	KBM7	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	-0.1748445568631254	[992,1045]	[260,576]	-2	hSpCas9	negative selection	287040
67769609	67769632	15	-	26472758	KBM7	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	0.03256991351550309	[166,205]	[79,100]	0	hSpCas9	negative selection	287041
67585909	67585932	15	+	26472758	KBM7	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	0.01638392199087324	[909,856]	[365,469]	0	hSpCas9	negative selection	287042
67630886	67630909	15	+	26472758	KBM7	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.4234784790311241	[806,605]	[427,452]	4	hSpCas9	negative selection	287043
67703333	67703356	15	+	26472758	Raji	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	0.4444185226511701	[189]	[59]	4	hSpCas9	negative selection	478152
67692498	67692521	15	+	26472758	Raji	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.6767491810437369	[61]	[22]	6	hSpCas9	negative selection	478153
67563314	67563337	15	+	26472758	Raji	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.176646197810713	[487]	[127]	1	hSpCas9	negative selection	478154
67580761	67580784	15	-	26472758	Raji	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.7782956489133712	[504]	[200]	7	hSpCas9	negative selection	478155
67580802	67580825	15	+	26472758	Raji	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.8888850301416428	[369]	[158]	7	hSpCas9	negative selection	478156
67600712	67600735	15	+	26472758	Raji	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	0.3496864996233069	[513]	[151]	3	hSpCas9	negative selection	478157
67769602	67769625	15	+	26472758	Raji	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	0.6042452576061248	[376]	[132]	6	hSpCas9	negative selection	478158
67769609	67769632	15	-	26472758	Raji	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	1.0293810233723264	[56]	[26]	8	hSpCas9	negative selection	478159
67585909	67585932	15	+	26472758	Raji	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	0.756886288289466	[305]	[119]	7	hSpCas9	negative selection	478160
67630886	67630909	15	+	26472758	Raji	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.08336030616708334	[544]	[133]	0	hSpCas9	negative selection	478161
67703333	67703356	15	+	26472758	K562	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	1.0034106281626518	[311]	[527]	8	hSpCas9	negative selection	669270
67692498	67692521	15	+	26472758	K562	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.8416595581660399	[116]	[176]	7	hSpCas9	negative selection	669271
67563314	67563337	15	+	26472758	K562	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.656091992911914	[965]	[1284]	5	hSpCas9	negative selection	669272
67580761	67580784	15	-	26472758	K562	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.7196122365077671	[1050]	[1460]	6	hSpCas9	negative selection	669273
67580802	67580825	15	+	26472758	K562	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.1353097274087316	[809]	[750]	1	hSpCas9	negative selection	669274
67600712	67600735	15	+	26472758	K562	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	0.5120558081751869	[990]	[1192]	4	hSpCas9	negative selection	669275
67769602	67769625	15	+	26472758	K562	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	0.4559228328601588	[797]	[923]	3	hSpCas9	negative selection	669276
67769609	67769632	15	-	26472758	K562	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	0.6640434964409425	[156]	[209]	5	hSpCas9	negative selection	669277
67585909	67585932	15	+	26472758	K562	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	0.35217490802232965	[734]	[791]	2	hSpCas9	negative selection	669278
67630886	67630909	15	+	26472758	K562	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.7047935925229536	[555]	[764]	6	hSpCas9	negative selection	669279
67543439	67543462	15	-	26627737	DLD1	viability	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-0.1369807163418189	[357]	[100,117,88]	-1	hSpCas9	negative selection	791464
67586840	67586863	15	+	26627737	DLD1	viability	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.3645151314307564	[227]	[105,67,0]	-4	hSpCas9	negative selection	791465
67600715	67600738	15	+	26627737	DLD1	viability	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-1.2696235438202637	[922]	[118,218,37]	-8	hSpCas9	negative selection	791466
67692498	67692521	15	+	26627737	DLD1	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.7424756233198024	[118]	[92,74,24]	7	hSpCas9	negative selection	791467
67727912	67727935	15	-	26627737	DLD1	viability	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	0.576676904760494	[125]	[95,45,36]	6	hSpCas9	negative selection	791468
67748574	67748597	15	-	26627737	DLD1	viability	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.2929312568076903	[879]	[437,496,116]	3	hSpCas9	negative selection	791469
67543439	67543462	15	-	26627737	GBM cells	viability after 5 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	0.5779985529713918	[177]	[159,124]	8	hSpCas9	negative selection	873779
67586840	67586863	15	+	26627737	GBM cells	viability after 5 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.6408965894430957	[172]	[70,47]	-7	hSpCas9	negative selection	873780
67600715	67600738	15	+	26627737	GBM cells	viability after 5 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-0.1276803351260275	[437]	[216,212]	-2	hSpCas9	negative selection	873781
67692498	67692521	15	+	26627737	GBM cells	viability after 5 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.9219974879987269	[30]	[38,23]	9	hSpCas9	negative selection	873782
67727912	67727935	15	-	26627737	GBM cells	viability after 5 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	1.1415692001146394	[100]	[93,144]	9	hSpCas9	negative selection	873783
67748574	67748597	15	-	26627737	GBM cells	viability after 5 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.5931254826535761	[499]	[362,445]	8	hSpCas9	negative selection	873784
67543439	67543462	15	-	26627737	GBM cells	viability after 13 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	0.4290638703157765	[177]	[193,77]	5	hSpCas9	negative selection	956094
67586840	67586863	15	+	26627737	GBM cells	viability after 13 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.23737554180197673	[172]	[88,71]	-3	hSpCas9	negative selection	956095
67600715	67600738	15	+	26627737	GBM cells	viability after 13 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-0.026586876468065346	[437]	[229,235]	0	hSpCas9	negative selection	956096
67692498	67692521	15	+	26627737	GBM cells	viability after 13 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	1.6160542527007709	[30]	[66,38]	9	hSpCas9	negative selection	956097
67727912	67727935	15	-	26627737	GBM cells	viability after 13 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	1.0423798347212172	[100]	[124,102]	9	hSpCas9	negative selection	956098
67748574	67748597	15	-	26627737	GBM cells	viability after 13 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.7523459814205751	[499]	[515,408]	8	hSpCas9	negative selection	956099
67543439	67543462	15	-	26627737	GBM cells	viability after 21 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-0.812975074434051	[177]	[53,55]	-6	hSpCas9	negative selection	1038409
67586840	67586863	15	+	26627737	GBM cells	viability after 21 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.3604042129246582	[172]	[79,66]	-3	hSpCas9	negative selection	1038410
67600715	67600738	15	+	26627737	GBM cells	viability after 21 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	0.29114763221008844	[437]	[298,283]	3	hSpCas9	negative selection	1038411
67692498	67692521	15	+	26627737	GBM cells	viability after 21 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	1.8874545269097316	[30]	[54,68]	9	hSpCas9	negative selection	1038412
67727912	67727935	15	-	26627737	GBM cells	viability after 21 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	1.6447407181831755	[100]	[204,140]	9	hSpCas9	negative selection	1038413
67748574	67748597	15	-	26627737	GBM cells	viability after 21 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.9441350179687418	[499]	[530,514]	8	hSpCas9	negative selection	1038414
67543439	67543462	15	-	26627737	RPE1	viability after 9 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-2.7342036868888915	[1978]	[86,100]	-9	hSpCas9	negative selection	1120724
67586840	67586863	15	+	26627737	RPE1	viability after 9 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-1.9887401110823912	[770]	[62,57]	-8	hSpCas9	negative selection	1120725
67600715	67600738	15	+	26627737	RPE1	viability after 9 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-1.3355279595062182	[1471]	[141,234]	-7	hSpCas9	negative selection	1120726
67692498	67692521	15	+	26627737	RPE1	viability after 9 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-3.5680903496613374	[706]	[5,34]	-9	hSpCas9	negative selection	1120727
67727912	67727935	15	-	26627737	RPE1	viability after 9 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	0.10858758329343532	[289]	[72,129]	0	hSpCas9	negative selection	1120728
67748574	67748597	15	-	26627737	RPE1	viability after 9 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.7232842901805128	[1434]	[649,859]	5	hSpCas9	negative selection	1120729
67543439	67543462	15	-	26627737	RPE1	viability after 12 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-2.181615725839489	[1978]	[106,127]	-8	hSpCas9	negative selection	1203039
67586840	67586863	15	+	26627737	RPE1	viability after 12 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-2.5710932227366143	[770]	[12,57]	-9	hSpCas9	negative selection	1203040
67600715	67600738	15	+	26627737	RPE1	viability after 12 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-1.841974722386984	[1471]	[103,116]	-8	hSpCas9	negative selection	1203041
67692498	67692521	15	+	26627737	RPE1	viability after 12 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-2.6205872023465773	[706]	[26,34]	-9	hSpCas9	negative selection	1203042
67727912	67727935	15	-	26627737	RPE1	viability after 12 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.0726742044334685	[289]	[42,106]	0	hSpCas9	negative selection	1203043
67748574	67748597	15	-	26627737	RPE1	viability after 12 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.47997238078102034	[1434]	[561,511]	3	hSpCas9	negative selection	1203044
67543439	67543462	15	-	26627737	RPE1	viability after 15 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-3.6856384403397895	[1978]	[14,70]	-9	hSpCas9	negative selection	1285354
67586840	67586863	15	+	26627737	RPE1	viability after 15 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-3.1739816313780818	[770]	[42,5]	-9	hSpCas9	negative selection	1285355
67600715	67600738	15	+	26627737	RPE1	viability after 15 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-2.1157969611505076	[1471]	[63,126]	-8	hSpCas9	negative selection	1285356
67692498	67692521	15	+	26627737	RPE1	viability after 15 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-7.643817530937505	[706]	[0,0]	-9	hSpCas9	negative selection	1285357
67727912	67727935	15	-	26627737	RPE1	viability after 15 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-2.6925349078526866	[289]	[1,22]	-9	hSpCas9	negative selection	1285358
67748574	67748597	15	-	26627737	RPE1	viability after 15 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.1136451237315147	[1434]	[427,449]	0	hSpCas9	negative selection	1285359
67543439	67543462	15	-	26627737	RPE1	viability after 18 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-3.816563259843825	[1978]	[5,71]	-9	hSpCas9	negative selection	1367669
67586840	67586863	15	+	26627737	RPE1	viability after 18 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-2.5790784192363425	[770]	[14,55]	-8	hSpCas9	negative selection	1367670
67600715	67600738	15	+	26627737	RPE1	viability after 18 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-2.2695204254821726	[1471]	[49,116]	-8	hSpCas9	negative selection	1367671
67692498	67692521	15	+	26627737	RPE1	viability after 18 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-3.7597789328772455	[706]	[1,26]	-9	hSpCas9	negative selection	1367672
67727912	67727935	15	-	26627737	RPE1	viability after 18 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-2.3327398795219185	[289]	[1,29]	-8	hSpCas9	negative selection	1367673
67748574	67748597	15	-	26627737	RPE1	viability after 18 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.3013235897490114	[1434]	[395,563]	2	hSpCas9	negative selection	1367674
67543439	67543462	15	-	26627737	HeLa	viability after 8 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	0.8771774523054814	[175]	[117,172,126]	7	hSpCas9	negative selection	1449984
67586840	67586863	15	+	26627737	HeLa	viability after 8 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-1.5930860123484072	[320]	[80,40,25]	-9	hSpCas9	negative selection	1449985
67600715	67600738	15	+	26627737	HeLa	viability after 8 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	0.2595595166280041	[542]	[416,265,200]	2	hSpCas9	negative selection	1449986
67692498	67692521	15	+	26627737	HeLa	viability after 8 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.981396774984263	[181]	[158,188,123]	7	hSpCas9	negative selection	1449987
67727912	67727935	15	-	26627737	HeLa	viability after 8 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.06826388103478373	[449]	[342,54,195]	0	hSpCas9	negative selection	1449988
67748574	67748597	15	-	26627737	HeLa	viability after 8 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.9595369003762206	[510]	[279,481,496]	7	hSpCas9	negative selection	1449989
67543439	67543462	15	-	26627737	HeLa	viability after 12 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	0.7013258816047364	[175]	[125,193,26]	5	hSpCas9	negative selection	1532299
67586840	67586863	15	+	26627737	HeLa	viability after 12 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-1.22693946730423	[320]	[41,33,95]	-8	hSpCas9	negative selection	1532300
67600715	67600738	15	+	26627737	HeLa	viability after 12 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	0.3012131259468444	[542]	[196,268,361]	2	hSpCas9	negative selection	1532301
67692498	67692521	15	+	26627737	HeLa	viability after 12 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-0.01752591358313582	[181]	[98,51,74]	0	hSpCas9	negative selection	1532302
67727912	67727935	15	-	26627737	HeLa	viability after 12 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.6551721498187415	[449]	[109,108,135]	-5	hSpCas9	negative selection	1532303
67748574	67748597	15	-	26627737	HeLa	viability after 12 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	1.1059530957210177	[510]	[539,247,599]	7	hSpCas9	negative selection	1532304
67543439	67543462	15	-	26627737	HeLa	viability after 15 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	1.015821926159739	[175]	[53,125,264]	7	hSpCas9	negative selection	1614614
67586840	67586863	15	+	26627737	HeLa	viability after 15 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-1.4478813170178333	[320]	[1,97,43]	-8	hSpCas9	negative selection	1614615
67600715	67600738	15	+	26627737	HeLa	viability after 15 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	0.00913042826974153	[542]	[205,197,266]	0	hSpCas9	negative selection	1614616
67692498	67692521	15	+	26627737	HeLa	viability after 15 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.4594737622271714	[181]	[103,82,119]	4	hSpCas9	negative selection	1614617
67727912	67727935	15	-	26627737	HeLa	viability after 15 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.1855265421399804	[449]	[185,98,200]	-1	hSpCas9	negative selection	1614618
67748574	67748597	15	-	26627737	HeLa	viability after 15 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	1.2834625565051796	[510]	[295,379,873]	8	hSpCas9	negative selection	1614619
67543439	67543462	15	-	26627737	HeLa	viability after 18 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	1.0316191529433105	[175]	[33,110,264]	7	hSpCas9	negative selection	1696929
67586840	67586863	15	+	26627737	HeLa	viability after 18 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-1.3674696199255751	[320]	[1,86,43]	-8	hSpCas9	negative selection	1696930
67600715	67600738	15	+	26627737	HeLa	viability after 18 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	0.03497427372742645	[542]	[145,163,266]	0	hSpCas9	negative selection	1696931
67692498	67692521	15	+	26627737	HeLa	viability after 18 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.46990790282253847	[181]	[70,68,119]	4	hSpCas9	negative selection	1696932
67727912	67727935	15	-	26627737	HeLa	viability after 18 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.1780852277953142	[449]	[127,79,200]	-1	hSpCas9	negative selection	1696933
67748574	67748597	15	-	26627737	HeLa	viability after 18 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	1.3042186867814312	[510]	[214,311,873]	8	hSpCas9	negative selection	1696934
67543439	67543462	15	-	26627737	HCT116	viability after 6 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	0.6025584180366923	[419]	[29,138]	3	hSpCas9	negative selection	1779244
67586840	67586863	15	+	26627737	HCT116	viability after 6 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.7008179251119289	[161]	[5,20]	-4	hSpCas9	negative selection	1779245
67600715	67600738	15	+	26627737	HCT116	viability after 6 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	0.7715453392136065	[934]	[306,219]	4	hSpCas9	negative selection	1779246
67692498	67692521	15	+	26627737	HCT116	viability after 6 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-0.9085890966304232	[372]	[76,5]	-5	hSpCas9	negative selection	1779247
67727912	67727935	15	-	26627737	HCT116	viability after 6 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.24942305927356356	[208]	[55,11]	-1	hSpCas9	negative selection	1779248
67748574	67748597	15	-	26627737	HCT116	viability after 6 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.7695085813243794	[1386]	[430,338]	4	hSpCas9	negative selection	1779249
67543439	67543462	15	-	26627737	HCT116	viability after 8 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	0.7918662496003166	[157]	[95,103,249]	7	hSpCas9	negative selection	1861559
67586840	67586863	15	+	26627737	HCT116	viability after 8 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.1974235717402723	[215]	[105,147,57]	-2	hSpCas9	negative selection	1861560
67600715	67600738	15	+	26627737	HCT116	viability after 8 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-0.7829142424334834	[586]	[210,216,136]	-7	hSpCas9	negative selection	1861561
67692498	67692521	15	+	26627737	HCT116	viability after 8 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-0.04714592817505203	[194]	[112,82,115]	0	hSpCas9	negative selection	1861562
67727912	67727935	15	-	26627737	HCT116	viability after 8 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	0.10430241728093881	[174]	[100,111,97]	1	hSpCas9	negative selection	1861563
67748574	67748597	15	-	26627737	HCT116	viability after 8 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.4262275367248307	[606]	[336,369,636]	4	hSpCas9	negative selection	1861564
67543439	67543462	15	-	26627737	HCT116	viability after 9 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	0.5897767845537156	[419]	[22,283]	4	hSpCas9	negative selection	1943874
67586840	67586863	15	+	26627737	HCT116	viability after 9 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	1.3387988116419653	[161]	[52,153]	8	hSpCas9	negative selection	1943875
67600715	67600738	15	+	26627737	HCT116	viability after 9 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-0.8699810112159172	[934]	[168,110]	-6	hSpCas9	negative selection	1943876
67692498	67692521	15	+	26627737	HCT116	viability after 9 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.20552542852597788	[372]	[101,124]	1	hSpCas9	negative selection	1943877
67727912	67727935	15	-	26627737	HCT116	viability after 9 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.3396920425864627	[208]	[66,25]	-2	hSpCas9	negative selection	1943878
67748574	67748597	15	-	26627737	HCT116	viability after 9 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.3807740962554862	[1386]	[627,366]	3	hSpCas9	negative selection	1943879
67543439	67543462	15	-	26627737	HCT116	viability after 12 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-0.10010460952739975	[157]	[62,90,79]	-1	hSpCas9	negative selection	2026189
67586840	67586863	15	+	26627737	HCT116	viability after 12 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.8805574971176524	[215]	[59,56,67]	-7	hSpCas9	negative selection	2026190
67600715	67600738	15	+	26627737	HCT116	viability after 12 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-0.6280787406366707	[586]	[177,211,210]	-6	hSpCas9	negative selection	2026191
67692498	67692521	15	+	26627737	HCT116	viability after 12 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-0.9974481209392171	[194]	[39,51,62]	-8	hSpCas9	negative selection	2026192
67727912	67727935	15	-	26627737	HCT116	viability after 12 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.8356693623316872	[174]	[41,74,38]	-7	hSpCas9	negative selection	2026193
67748574	67748597	15	-	26627737	HCT116	viability after 12 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.07844216826226558	[606]	[260,496,262]	0	hSpCas9	negative selection	2026194
67543439	67543462	15	-	26627737	HCT116	viability after 15 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-0.0608507218113965	[157]	[79,82,96]	0	hSpCas9	negative selection	2108504
67586840	67586863	15	+	26627737	HCT116	viability after 15 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.5438764096438171	[215]	[71,40,139]	-5	hSpCas9	negative selection	2108505
67600715	67600738	15	+	26627737	HCT116	viability after 15 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-1.5726918750230425	[586]	[124,151,64]	-8	hSpCas9	negative selection	2108506
67692498	67692521	15	+	26627737	HCT116	viability after 15 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-1.15636628574067	[194]	[68,32,50]	-8	hSpCas9	negative selection	2108507
67727912	67727935	15	-	26627737	HCT116	viability after 15 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.48286970493857095	[174]	[55,101,55]	-5	hSpCas9	negative selection	2108508
67748574	67748597	15	-	26627737	HCT116	viability after 15 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.03489950693064059	[606]	[280,412,367]	0	hSpCas9	negative selection	2108509
67543439	67543462	15	-	26627737	HCT116	viability after 18 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-0.7801299010996418	[157]	[40,23,70]	-6	hSpCas9	negative selection	2190819
67586840	67586863	15	+	26627737	HCT116	viability after 18 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-2.1514461433267127	[215]	[6,8,56]	-9	hSpCas9	negative selection	2190820
67600715	67600738	15	+	26627737	HCT116	viability after 18 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-1.425145800431154	[586]	[61,140,111]	-8	hSpCas9	negative selection	2190821
67692498	67692521	15	+	26627737	HCT116	viability after 18 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-2.0525186271519535	[194]	[31,28,5]	-9	hSpCas9	negative selection	2190822
67727912	67727935	15	-	26627737	HCT116	viability after 18 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.6182689279288475	[174]	[56,82,21]	-5	hSpCas9	negative selection	2190823
67748574	67748597	15	-	26627737	HCT116	viability after 18 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.22134630516819986	[606]	[265,461,287]	2	hSpCas9	negative selection	2190824
67550022	67550045	15	+	24336569	HL60	viability	TTCTTTGTTTAGGATGTGATAGG	MAP2K5	ENSG00000137764	1.0332553987899618	[292]	[1268]	7	hSpCas9	negative selection	2275788
67550027	67550050	15	+	24336569	HL60	viability	TGTTTAGGATGTGATAGGCCAGG	MAP2K5	ENSG00000137764	0.5499577111849201	[824]	[2555]	5	hSpCas9	negative selection	2275789
67550045	67550068	15	-	24336569	HL60	viability	TTGTTGCTTCAGGCAGAACCTGG	MAP2K5	ENSG00000137764	1.3933628934081055	[160]	[894]	8	hSpCas9	negative selection	2275790
67550055	67550078	15	-	24336569	HL60	viability	AATGCTGTAGTTGTTGCTTCAGG	MAP2K5	ENSG00000137764	0.14131934796049134	[526]	[1229]	1	hSpCas9	negative selection	2275791
67563276	67563299	15	+	24336569	HL60	viability	TAAACAGATGAAGATGAAGATGG	MAP2K5	ENSG00000137764	-0.362719790138546	[493]	[812]	-3	hSpCas9	negative selection	2275792
67563305	67563328	15	+	24336569	HL60	viability	AATTACAGTGAGAAGTGATGAGG	MAP2K5	ENSG00000137764	1.1247460668953857	[998]	[4609]	8	hSpCas9	negative selection	2275793
67563314	67563337	15	+	24336569	HL60	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.5080602854455171	[841]	[2533]	4	hSpCas9	negative selection	2275794
67580750	67580773	15	+	24336569	HL60	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	1.2858335472927964	[456]	[2357]	8	hSpCas9	negative selection	2275795
67580761	67580784	15	-	24336569	HL60	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.05162413263304447	[475]	[1043]	0	hSpCas9	negative selection	2275796
67580766	67580789	15	+	24336569	HL60	viability	GTAATGGAACAGCAAGTAAATGG	MAP2K5	ENSG00000137764	0.1301256117472105	[1148]	[2660]	1	hSpCas9	negative selection	2275797
67550022	67550045	15	+	24336569	KBM7	viability	TTCTTTGTTTAGGATGTGATAGG	MAP2K5	ENSG00000137764	0.46124660396535	[595]	[2237]	4	hSpCas9	negative selection	2342965
67550027	67550050	15	+	24336569	KBM7	viability	TGTTTAGGATGTGATAGGCCAGG	MAP2K5	ENSG00000137764	-0.3831181806601587	[568]	[1189]	-3	hSpCas9	negative selection	2342966
67550045	67550068	15	-	24336569	KBM7	viability	TTGTTGCTTCAGGCAGAACCTGG	MAP2K5	ENSG00000137764	-2.775153854577387	[383]	[152]	-9	hSpCas9	negative selection	2342967
67550055	67550078	15	-	24336569	KBM7	viability	AATGCTGTAGTTGTTGCTTCAGG	MAP2K5	ENSG00000137764	0.7274142493969464	[220]	[997]	6	hSpCas9	negative selection	2342968
67563276	67563299	15	+	24336569	KBM7	viability	TAAACAGATGAAGATGAAGATGG	MAP2K5	ENSG00000137764	0.2565356869204145	[572]	[1866]	2	hSpCas9	negative selection	2342969
67563305	67563328	15	+	24336569	KBM7	viability	AATTACAGTGAGAAGTGATGAGG	MAP2K5	ENSG00000137764	0.07387632747836936	[1191]	[3421]	0	hSpCas9	negative selection	2342970
67563314	67563337	15	+	24336569	KBM7	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	-0.31795176507773737	[717]	[1570]	-3	hSpCas9	negative selection	2342971
67580750	67580773	15	+	24336569	KBM7	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.8445803884886744	[283]	[1390]	7	hSpCas9	negative selection	2342972
67580761	67580784	15	-	24336569	KBM7	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.1741690379508689	[253]	[613]	-1	hSpCas9	negative selection	2342973
67580766	67580789	15	+	24336569	KBM7	viability	GTAATGGAACAGCAAGTAAATGG	MAP2K5	ENSG00000137764	0.9866010231892308	[874]	[4728]	8	hSpCas9	negative selection	2342974
67705500	67705523	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGGTGGGCAGATCACCTGAAG	MAP2K5	ENSG00000137764	-0.9435702514495408	[62,8]	[4,2]	-5	dCas9-VP64	positive selection	2385203
67632148	67632171	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGCGTGATCTAGG	MAP2K5	ENSG00000137764	1.5299201678265226	[5,69]	[1,47]	6	dCas9-VP64	positive selection	2386509
67712656	67712679	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCCTGTAATCCCAACACTTTAG	MAP2K5	ENSG00000137764	-0.41262403252634594	[72,406]	[43,35]	-2	dCas9-VP64	positive selection	2388793
67548793	67548816	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGTTGATGTTTCATTTGTGAGG	MAP2K5	ENSG00000137764	2.078436320024271	[32,44]	[11,62]	7	dCas9-VP64	positive selection	2412526
67548838	67548861	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTTTGGCTGTAATGAGCAAGG	MAP2K5	ENSG00000137764	-0.3385369034051461	[44,212]	[6,38]	-1	dCas9-VP64	positive selection	2412527
67548865	67548888	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGATCAAAGAGGACTATCTTAGG	MAP2K5	ENSG00000137764	-2.276104632216612	[616,68]	[21,6]	-9	dCas9-VP64	positive selection	2412528
67567555	67567578	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCTTGTTAGCCGGG	MAP2K5	ENSG00000137764	-1.1294869008101784	[149,112]	[16,8]	-6	dCas9-VP64	positive selection	2413721
67577126	67577149	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCTTGTTAGCCGGG	MAP2K5	ENSG00000137764	-1.1294869008101784	[149,112]	[16,8]	-6	dCas9-VP64	positive selection	2413723
67647823	67647846	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGCCACTGCACTCCACCCTGG	MAP2K5	ENSG00000137764	1.8834074276407538	[71,51]	[70,27]	6	dCas9-VP64	positive selection	2443944
67718529	67718552	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGGTGGGTGGATCACTTGAAG	MAP2K5	ENSG00000137764	0.9269503688862448	[9,0]	[1,1]	4	dCas9-VP64	positive selection	2463094
67574360	67574383	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGTTTGAGACCAGCTTGG	MAP2K5	ENSG00000137764	0.362963240197711	[121,64]	[24,26]	1	dCas9-VP64	positive selection	2472637
67624678	67624701	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGTGCAATCTCAG	MAP2K5	ENSG00000137764	-0.951887234031858	[136,22]	[13,2]	-5	dCas9-VP64	positive selection	2476154
67705500	67705523	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGGTGGGCAGATCACCTGAAG	MAP2K5	ENSG00000137764	-1.0522246340753525	[77,52]	[9,9]	-8	dCas9-VP64	positive selection	2480458
67632148	67632171	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGCGTGATCTAGG	MAP2K5	ENSG00000137764	0.46408056547853904	[52,55]	[23,24]	3	dCas9-VP64	positive selection	2481764
67712656	67712679	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCCTGTAATCCCAACACTTTAG	MAP2K5	ENSG00000137764	-0.2657724594178119	[436,92]	[111,35]	-3	dCas9-VP64	positive selection	2484048
67548793	67548816	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGTTGATGTTTCATTTGTGAGG	MAP2K5	ENSG00000137764	0.24619263295424387	[232,93]	[50,75]	2	dCas9-VP64	positive selection	2507781
67548838	67548861	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTTTGGCTGTAATGAGCAAGG	MAP2K5	ENSG00000137764	0.18178285694264892	[116,148]	[59,37]	1	dCas9-VP64	positive selection	2507782
67548865	67548888	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGATCAAAGAGGACTATCTTAGG	MAP2K5	ENSG00000137764	0.8134404359087204	[93,140]	[36,95]	5	dCas9-VP64	positive selection	2507783
67567555	67567578	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCTTGTTAGCCGGG	MAP2K5	ENSG00000137764	1.9539419511074274	[45,81]	[33,122]	8	dCas9-VP64	positive selection	2508976
67577126	67577149	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCTTGTTAGCCGGG	MAP2K5	ENSG00000137764	1.9539419511074274	[45,81]	[33,122]	8	dCas9-VP64	positive selection	2508978
67647823	67647846	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGCCACTGCACTCCACCCTGG	MAP2K5	ENSG00000137764	-0.10769466573443187	[156,168]	[45,51]	-1	dCas9-VP64	positive selection	2539199
67718529	67718552	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGGTGGGTGGATCACTTGAAG	MAP2K5	ENSG00000137764	-0.7008385215102662	[31,39]	[9,2]	-6	dCas9-VP64	positive selection	2558349
67574360	67574383	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGTTTGAGACCAGCTTGG	MAP2K5	ENSG00000137764	-1.016658803330618	[35,140]	[14,11]	-8	dCas9-VP64	positive selection	2567892
67624678	67624701	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGTGCAATCTCAG	MAP2K5	ENSG00000137764	-1.0138866146493042	[45,103]	[11,10]	-8	dCas9-VP64	positive selection	2571409
67586836	67586859	15	+	27013184	SW480	treatment with recombinant TRAIL	TTACTTATAGGTGAATACTCGGG	MAP2K5	ENSG00000137764	-0.5117766350679597	[141,341]	[32,123]	-2	hSpCas9	positive selection	2960496
67586840	67586863	15	+	27013184	SW480	treatment with recombinant TRAIL	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-4.590389782218073	[143,72]	[1,1]	-9	hSpCas9	positive selection	2960497
67586892	67586915	15	+	27013184	SW480	treatment with recombinant TRAIL	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	2.2878660766963503	[222,141]	[477,269]	8	hSpCas9	positive selection	2960498
67585883	67585906	15	+	27013184	SW480	treatment with recombinant TRAIL	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.09487209399736374	[403,610]	[46,420]	0	hSpCas9	positive selection	2960499
67543322	67543345	15	+	27013184	SW480	treatment with recombinant TRAIL	CTCTTTAACCTGTAATGCTGTGG	MAP2K5	ENSG00000137764	2.1900909094770555	[82,82]	[70,294]	8	hSpCas9	positive selection	2960500
67543333	67543356	15	+	27013184	SW480	treatment with recombinant TRAIL	GTAATGCTGTGGCTAGCCCTTGG	MAP2K5	ENSG00000137764	1.3956394923667506	[163,43]	[67,203]	6	hSpCas9	positive selection	2960501
67543359	67543382	15	+	27013184	SW480	treatment with recombinant TRAIL	CTTTCCTGCCATGGAGAACCAGG	MAP2K5	ENSG00000137764	2.2229973635755944	[142,205]	[328,369]	8	hSpCas9	positive selection	2960502
67543365	67543388	15	+	27013184	SW480	treatment with recombinant TRAIL	TGCCATGGAGAACCAGGTGCTGG	MAP2K5	ENSG00000137764	0.5544697367532262	[148,132]	[147,6]	2	hSpCas9	positive selection	2960503
67748560	67748583	15	-	27013184	SW480	treatment with recombinant TRAIL	AGAAGCTGGAGAGGCTGCAATGG	MAP2K5	ENSG00000137764	0.182618653220461	[30,56]	[1,47]	0	hSpCas9	positive selection	2960504
67543393	67543416	15	+	27013184	SW480	treatment with recombinant TRAIL	CGCATCAAGATCCCAAATAGTGG	MAP2K5	ENSG00000137764	-0.9635207008863291	[110,66]	[15,25]	-4	hSpCas9	positive selection	2960505
67543398	67543421	15	+	27013184	SW480	treatment with recombinant TRAIL	CAAGATCCCAAATAGTGGCGCGG	MAP2K5	ENSG00000137764	-1.5483937827853875	[8,18]	[1,1]	-6	hSpCas9	positive selection	2960506
67748574	67748597	15	-	27013184	SW480	treatment with recombinant TRAIL	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	2.140284169746063	[59,97]	[163,122]	8	hSpCas9	positive selection	2960507
67543401	67543424	15	+	27013184	SW480	treatment with recombinant TRAIL	GATCCCAAATAGTGGCGCGGTGG	MAP2K5	ENSG00000137764	0.5963216724274227	[36,163]	[32,102]	3	hSpCas9	positive selection	2960508
67543406	67543429	15	+	27013184	SW480	treatment with recombinant TRAIL	CAAATAGTGGCGCGGTGGACTGG	MAP2K5	ENSG00000137764	1.5237906354575537	[101,74]	[55,189]	7	hSpCas9	positive selection	2960509
67543420	67543443	15	+	27013184	SW480	treatment with recombinant TRAIL	GTGGACTGGACAGTGCACTCCGG	MAP2K5	ENSG00000137764	0.5657855744065616	[89,66]	[63,31]	3	hSpCas9	positive selection	2960510
67543421	67543444	15	+	27013184	SW480	treatment with recombinant TRAIL	TGGACTGGACAGTGCACTCCGGG	MAP2K5	ENSG00000137764	1.8114817029888943	[115,167]	[211,210]	7	hSpCas9	positive selection	2960511
67543439	67543462	15	+	27013184	SW480	treatment with recombinant TRAIL	CCGGGCCGCAGTTACTCTTCAGG	MAP2K5	ENSG00000137764	1.1047820050762194	[521,434]	[568,274]	5	hSpCas9	positive selection	2960512
67543440	67543463	15	+	27013184	SW480	treatment with recombinant TRAIL	CGGGCCGCAGTTACTCTTCAGGG	MAP2K5	ENSG00000137764	0.5966714150962664	[679,612]	[396,461]	3	hSpCas9	positive selection	2960513
67550070	67550093	15	+	27013184	SW480	treatment with recombinant TRAIL	ACAGCATTTGAATGTAAGTCTGG	MAP2K5	ENSG00000137764	-0.5905855094171969	[514,662]	[78,291]	-3	hSpCas9	positive selection	2960514
67543449	67543472	15	+	27013184	SW480	treatment with recombinant TRAIL	GTTACTCTTCAGGGATGTGCTGG	MAP2K5	ENSG00000137764	0.9889870118865252	[506,723]	[527,505]	5	hSpCas9	positive selection	2960515
67585898	67585921	15	-	27013184	SW480	treatment with recombinant TRAIL	TGTATGTTCCGTTCCCCAGGAGG	MAP2K5	ENSG00000137764	2.905328057895992	[35,76]	[196,147]	9	hSpCas9	positive selection	2960516
67585901	67585924	15	-	27013184	SW480	treatment with recombinant TRAIL	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	1.2579647498087292	[360,441]	[460,338]	6	hSpCas9	positive selection	2960517
67585924	67585947	15	-	27013184	SW480	treatment with recombinant TRAIL	TTATTGAAATTCGTACCTTCAGG	MAP2K5	ENSG00000137764	-1.4975840965572405	[103,66]	[2,27]	-6	hSpCas9	positive selection	2960518
67586881	67586904	15	-	27013184	SW480	treatment with recombinant TRAIL	GAAGTGAATCTGAGACTGCTGGG	MAP2K5	ENSG00000137764	1.1951816082818212	[54,88]	[67,71]	5	hSpCas9	positive selection	2960519
67586882	67586905	15	-	27013184	SW480	treatment with recombinant TRAIL	GGAAGTGAATCTGAGACTGCTGG	MAP2K5	ENSG00000137764	2.0316235335620654	[40,41]	[61,88]	8	hSpCas9	positive selection	2960520
67550045	67550068	15	-	27013184	SW480	treatment with recombinant TRAIL	TTGTTGCTTCAGGCAGAACCTGG	MAP2K5	ENSG00000137764	2.954150695324799	[496,326]	[1244,1627]	9	hSpCas9	positive selection	2960521
67550055	67550078	15	-	27013184	SW480	treatment with recombinant TRAIL	AATGCTGTAGTTGTTGCTTCAGG	MAP2K5	ENSG00000137764	-2.3050908664581327	[204,169]	[25,2]	-8	hSpCas9	positive selection	2960522
67585890	67585913	15	+	27013184	SW480	treatment with recombinant TRAIL	CCTGCAAGCCTCCTGGGGAACGG	MAP2K5	ENSG00000137764	1.8415615350406158	[145,57]	[124,218]	7	hSpCas9	positive selection	2960523
67585901	67585924	15	+	27013184	SW480	treatment with recombinant TRAIL	CCTGGGGAACGGAACATACATGG	MAP2K5	ENSG00000137764	0.2829979475391333	[405,749]	[247,362]	1	hSpCas9	positive selection	2960524
67586835	67586858	15	+	27013184	SW480	treatment with recombinant TRAIL	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	-1.8046988396119668	[64,123]	[12,8]	-7	hSpCas9	positive selection	2960525
67580803	67580826	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.4275660612169815	[3,3]	[3,5]	8	hSpCas9	positive selection	3001116
67549170	67549193	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGGACTGGACATGATGGAGGG	MAP2K5	ENSG00000137764	-1.178612231560234	[3,3]	[0,0]	-9	hSpCas9	positive selection	3001117
67585898	67585921	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTATGTTCCGTTCCCCAGGAGG	MAP2K5	ENSG00000137764	-0.2436870243671062	[4,4]	[3,3]	-3	hSpCas9	positive selection	3001118
67586837	67586860	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACTTATAGGTGAATACTCGGG	MAP2K5	ENSG00000137764	0.09513891655484383	[4,4]	[3,3]	2	hSpCas9	positive selection	3001119
67580803	67580826	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	-0.5467578729094753	[3,3]	[2,0]	-7	hSpCas9	positive selection	3068974
67549170	67549193	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGGACTGGACATGATGGAGGG	MAP2K5	ENSG00000137764	0.27101249003523714	[3,3]	[3,2]	5	hSpCas9	positive selection	3068975
67585898	67585921	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTATGTTCCGTTCCCCAGGAGG	MAP2K5	ENSG00000137764	-0.03175505432722253	[4,4]	[5,1]	0	hSpCas9	positive selection	3068976
67586837	67586860	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACTTATAGGTGAATACTCGGG	MAP2K5	ENSG00000137764	-0.0627504885802158	[4,4]	[3,1]	-1	hSpCas9	positive selection	3068977
67585901	67585924		-	24336571	A375	resistance to PLX after 7 days	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	-0.17242913772306423	[63,66]	[59,54]	-5	hSpCas9	positive selection	3126256
67580802	67580825		-	24336571	A375	resistance to PLX after 7 days	CCTCTTGGAAATATCTGCAGAGG	MAP2K5	ENSG00000137764	-0.018722067962444855	[11,11]	[11,11]	0	hSpCas9	positive selection	3126257
67585883	67585906		+	24336571	A375	resistance to PLX after 7 days	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.2326867268774162	[39,40]	[35,32]	-7	hSpCas9	positive selection	3126258
67580761	67580784		-	24336571	A375	resistance to PLX after 7 days	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.022465594147937917	[65,68]	[65,66]	0	hSpCas9	positive selection	3126259
67585901	67585924		-	24336571	A375	resistance to PLX after 14 days	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	-0.5844761122212598	[74,59]	[19,20]	-7	hSpCas9	positive selection	3184049
67580802	67580825		-	24336571	A375	resistance to PLX after 14 days	CCTCTTGGAAATATCTGCAGAGG	MAP2K5	ENSG00000137764	-0.5908110497227208	[10,18]	[3,4]	-7	hSpCas9	positive selection	3184050
67585883	67585906		+	24336571	A375	resistance to PLX after 14 days	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.6373372158035875	[37,45]	[12,11]	-7	hSpCas9	positive selection	3184051
67580761	67580784		-	24336571	A375	resistance to PLX after 14 days	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.7497519860445596	[48,85]	[21,14]	-8	hSpCas9	positive selection	3184052
67585901	67585924		-	24336571	A375	viability after 7 days	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.019744653659174993	[67]	[63,66]	0	hSpCas9	negative selection	3241842
67580802	67580825		-	24336571	A375	viability after 7 days	CCTCTTGGAAATATCTGCAGAGG	MAP2K5	ENSG00000137764	-0.6285156343816587	[19]	[11,11]	-7	hSpCas9	negative selection	3241843
67585883	67585906		+	24336571	A375	viability after 7 days	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.32185186014560774	[33]	[39,40]	5	hSpCas9	negative selection	3241844
67580761	67580784		-	24336571	A375	viability after 7 days	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.11387103411712385	[76]	[65,68]	-2	hSpCas9	negative selection	3241845
67585901	67585924		-	24336571	A375	viability after 14 days	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.07951738852731438	[67]	[74,59]	1	hSpCas9	negative selection	3299635
67580802	67580825		-	24336571	A375	viability after 14 days	CCTCTTGGAAATATCTGCAGAGG	MAP2K5	ENSG00000137764	-0.30036458429885987	[19]	[10,18]	-4	hSpCas9	negative selection	3299636
67585883	67585906		+	24336571	A375	viability after 14 days	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.3805423338827394	[33]	[37,45]	5	hSpCas9	negative selection	3299637
67580761	67580784		-	24336571	A375	viability after 14 days	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.10416589563026113	[76]	[48,85]	-1	hSpCas9	negative selection	3299638
67580761	67580784	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-1.1897570147638172	[348,348]	[0,0]	-7	hSpCas9	positive selection	3378382
67585883	67585906	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	1.3504356158373165	[119,119]	[1,1]	6	hSpCas9	positive selection	3378383
67580750	67580773	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	8.210020496667479	[402,402]	[779,779]	9	hSpCas9	positive selection	3378384
67580802	67580825	15	+	26780180	HT29	viability (Avana library 4 designs)	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	1.27920731290319	[]	[]	5	hSpCas9	negative selection	3438760
67549169	67549192	15	+	26780180	HT29	viability (Avana library 4 designs)	GTTGGACTGGACATGATGGAGGG	MAP2K5	ENSG00000137764	1.04335984758964	[]	[]	4	hSpCas9	negative selection	3438761
67585898	67585921	15	-	26780180	HT29	viability (Avana library 4 designs)	TGTATGTTCCGTTCCCCAGGAGG	MAP2K5	ENSG00000137764	0.552244634409198	[]	[]	2	hSpCas9	negative selection	3438762
67586836	67586859	15	+	26780180	HT29	viability (Avana library 4 designs)	TTACTTATAGGTGAATACTCGGG	MAP2K5	ENSG00000137764	1.85340551322631	[]	[]	7	hSpCas9	negative selection	3438763
67549169	67549192	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGGACTGGACATGATGGAGGG	MAP2K5	ENSG00000137764	5.10624691947096	[]	[]	8	hSpCas9	negative selection	3528169
67580802	67580825	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	3.32076003370385	[]	[]	5	hSpCas9	negative selection	3528170
67585898	67585921	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTATGTTCCGTTCCCCAGGAGG	MAP2K5	ENSG00000137764	2.64739445720375	[]	[]	4	hSpCas9	negative selection	3528171
67586836	67586859	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACTTATAGGTGAATACTCGGG	MAP2K5	ENSG00000137764	-14.9667119069992	[]	[]	-9	hSpCas9	negative selection	3528172
67580750	67580773	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-2.57368798019259	[]	[]	-3	hSpCas9	negative selection	3528173
67586903	67586926	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCGCTCGCACCTATTGCTTGG	MAP2K5	ENSG00000137764	1.78661638226773	[]	[]	2	hSpCas9	negative selection	3528174
67549169	67549192	15	+	26780180	A375	viability (Avana lentiGuide)	GTTGGACTGGACATGATGGAGGG	MAP2K5	ENSG00000137764	1.02948922533241	[]	[]	1	hSpCas9	negative selection	3636828
67580802	67580825	15	+	26780180	A375	viability (Avana lentiGuide)	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	-2.91343950813981	[]	[]	-5	hSpCas9	negative selection	3636829
67585898	67585921	15	-	26780180	A375	viability (Avana lentiGuide)	TGTATGTTCCGTTCCCCAGGAGG	MAP2K5	ENSG00000137764	-0.377359522391884	[]	[]	0	hSpCas9	negative selection	3636830
67586836	67586859	15	+	26780180	A375	viability (Avana lentiGuide)	TTACTTATAGGTGAATACTCGGG	MAP2K5	ENSG00000137764	5.88447363433028	[]	[]	5	hSpCas9	negative selection	3636831
67580750	67580773	15	+	26780180	A375	viability (Avana lentiGuide)	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.471173676607703	[]	[]	0	hSpCas9	negative selection	3636832
67586903	67586926	15	-	26780180	A375	viability (Avana lentiGuide)	GCTCGCTCGCACCTATTGCTTGG	MAP2K5	ENSG00000137764	-0.108771394838055	[]	[]	0	hSpCas9	negative selection	3636833
67549169	67549192	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGGACTGGACATGATGGAGGG	MAP2K5	ENSG00000137764	0.20669309307329464	[4]	[5,5]	6	hSpCas9	positive selection	3745487
67580802	67580825	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	-0.057038213374968165	[5]	[6,3]	-1	hSpCas9	positive selection	3745488
67585898	67585921	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTATGTTCCGTTCCCCAGGAGG	MAP2K5	ENSG00000137764	-0.03837527051882067	[5]	[6,4]	0	hSpCas9	positive selection	3745489
67586836	67586859	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACTTATAGGTGAATACTCGGG	MAP2K5	ENSG00000137764	-0.6417166753384792	[8]	[4,5]	-7	hSpCas9	positive selection	3745490
67580750	67580773	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.5493022648271646	[6]	[4,3]	-7	hSpCas9	positive selection	3745491
67586903	67586926	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCGCTCGCACCTATTGCTTGG	MAP2K5	ENSG00000137764	0.057951259745324196	[5]	[5,6]	1	hSpCas9	positive selection	3745492
67549169	67549192	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGGACTGGACATGATGGAGGG	MAP2K5	ENSG00000137764	-0.2225480233697825	[5]	[2,4]	-3	hSpCas9	positive selection	3854094
67580802	67580825	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	-0.07764007864570609	[5]	[5,2]	-1	hSpCas9	positive selection	3854095
67585898	67585921	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTATGTTCCGTTCCCCAGGAGG	MAP2K5	ENSG00000137764	0.22702215448643082	[6]	[7,6]	6	hSpCas9	positive selection	3854096
67586836	67586859	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACTTATAGGTGAATACTCGGG	MAP2K5	ENSG00000137764	-0.13715087712191956	[6]	[5,3]	-2	hSpCas9	positive selection	3854097
67580750	67580773	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.09463540848172897	[4]	[1,5]	2	hSpCas9	positive selection	3854098
67586903	67586926	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCGCTCGCACCTATTGCTTGG	MAP2K5	ENSG00000137764	0.21669901214143977	[7]	[7,7]	5	hSpCas9	positive selection	3854099
67586892	67586915	15	+	26780180	A375	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.0281997923052041	[]	[]	0	hSpCas9	negative selection	3959609
67585901	67585924	15	-	26780180	A375	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	1.31256407414598	[]	[]	7	hSpCas9	negative selection	3959610
67580750	67580773	15	+	26780180	A375	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.961844090698531	[]	[]	4	hSpCas9	negative selection	3959611
67585883	67585906	15	+	26780180	A375	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	1.2087201662936	[]	[]	6	hSpCas9	negative selection	3959612
67580761	67580784	15	-	26780180	A375	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.704418656297104	[]	[]	2	hSpCas9	negative selection	3959613
67586835	67586858	15	+	26780180	A375	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.351629195542796	[]	[]	0	hSpCas9	negative selection	3959614
67586892	67586915	15	+	26780180	HT29	viability (GeCKOv2 library)	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	-0.256467240748278	[]	[]	-6	hSpCas9	negative selection	4067575
67585901	67585924	15	-	26780180	HT29	viability (GeCKOv2 library)	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.965634740979636	[]	[]	4	hSpCas9	negative selection	4067576
67580750	67580773	15	+	26780180	HT29	viability (GeCKOv2 library)	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.380879441497485	[]	[]	1	hSpCas9	negative selection	4067577
67585883	67585906	15	+	26780180	HT29	viability (GeCKOv2 library)	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	1.2623651283996	[]	[]	6	hSpCas9	negative selection	4067578
67580761	67580784	15	-	26780180	HT29	viability (GeCKOv2 library)	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	1.21798586832976	[]	[]	6	hSpCas9	negative selection	4067579
67586835	67586858	15	+	26780180	HT29	viability (GeCKOv2 library)	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.676884375575557	[]	[]	2	hSpCas9	negative selection	4067580
67585901	67585924	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.07195703517801322	[6]	[4,4]	1	hSpCas9	positive selection	4150472
67580802	67580825	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTCTTGGAAATATCTGCAGAGG	MAP2K5	ENSG00000137764	-0.22279342540055452	[4]	[2,1]	-5	hSpCas9	positive selection	4150473
67585883	67585906	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.006163766544737714	[5]	[3,3]	0	hSpCas9	positive selection	4150474
67580761	67580784	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.07643859535250896	[6]	[4,4]	2	hSpCas9	positive selection	4150475
67585901	67585924	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	1.0740085005894766	[5]	[4,3,6,5]	7	hSpCas9	positive selection	4214494
67580802	67580825	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTCTTGGAAATATCTGCAGAGG	MAP2K5	ENSG00000137764	0.5967389537676929	[3]	[0,0,0,3]	4	hSpCas9	positive selection	4214495
67585883	67585906	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.9955060716975577	[4]	[4,4,2,4]	7	hSpCas9	positive selection	4214496
67580761	67580784	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.23826888024495507	[5]	[5,3,4,0]	1	hSpCas9	positive selection	4214497
67585901	67585924	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.3086863615288492	[4]	[4,4]	6	hSpCas9	positive selection	4281810
67586892	67586915	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.5048309144932622	[3]	[4,3]	9	hSpCas9	positive selection	4281811
67586835	67586858	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.20675075282981545	[3]	[3,1]	4	hSpCas9	positive selection	4281812
67580761	67580784	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.0563985257149594	[3]	[3,2]	1	hSpCas9	positive selection	4346068
67585883	67585906	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.2256520859562318	[2]	[3,0]	-4	hSpCas9	positive selection	4346069
67580750	67580773	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.26719966308115906	[4]	[4,3]	5	hSpCas9	positive selection	4346070
67580803	67580825	15	+	27760321	OCIAML3	viability	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.5685944140472592	[140,136]	[105,233]	6	hSpCas9	negative selection	4416560
67586893	67586915	15	+	27760321	OCIAML3	viability	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	-0.2834077116317455	[277,238]	[205,112]	-3	hSpCas9	negative selection	4416561
67600707	67600729	15	+	27760321	OCIAML3	viability	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	-0.18236687899481474	[537,412]	[326,322]	-2	hSpCas9	negative selection	4416562
67630900	67630922	15	-	27760321	OCIAML3	viability	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	0.15919712862117663	[221,173]	[133,220]	1	hSpCas9	negative selection	4416563
67646234	67646256	15	+	27760321	OCIAML3	viability	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	-1.5072062682584981	[1,4]	[0,0]	-8	hSpCas9	negative selection	4416564
67580803	67580825	15	+	27760321	OCIAML2	viability	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	1.038272811246948	[140,136]	[148,339]	9	hSpCas9	negative selection	4500023
67586893	67586915	15	+	27760321	OCIAML2	viability	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.7591363138613401	[277,238]	[263,469]	8	hSpCas9	negative selection	4500024
67600707	67600729	15	+	27760321	OCIAML2	viability	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	0.1665106659529436	[537,412]	[399,465]	2	hSpCas9	negative selection	4500025
67630900	67630922	15	-	27760321	OCIAML2	viability	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	0.6818380140185988	[221,173]	[199,327]	8	hSpCas9	negative selection	4500026
67646234	67646256	15	+	27760321	OCIAML2	viability	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	-1.5559516335235468	[1,4]	[0,0]	-8	hSpCas9	negative selection	4500027
67580803	67580825	15	+	27760321	MV411	viability	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.9420917120879451	[140,136]	[182,166]	7	hSpCas9	negative selection	4583486
67586893	67586915	15	+	27760321	MV411	viability	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	1.7425315267523138	[277,238]	[511,654]	9	hSpCas9	negative selection	4583487
67600707	67600729	15	+	27760321	MV411	viability	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	-0.8342660301968615	[537,412]	[17,409]	-5	hSpCas9	negative selection	4583488
67630900	67630922	15	-	27760321	MV411	viability	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	1.1932022179003936	[221,173]	[267,339]	8	hSpCas9	negative selection	4583489
67646234	67646256	15	+	27760321	MV411	viability	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	1.9067335637713079	[1,4]	[0,20]	9	hSpCas9	negative selection	4583490
67580803	67580825	15	+	27760321	HL60	viability	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.6258688178270224	[140,136]	[194,154]	7	hSpCas9	negative selection	4666949
67586893	67586915	15	+	27760321	HL60	viability	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	-0.48312771432369295	[277,238]	[154,145]	-5	hSpCas9	negative selection	4666950
67600707	67600729	15	+	27760321	HL60	viability	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	0.19751062129099492	[537,412]	[460,421]	2	hSpCas9	negative selection	4666951
67630900	67630922	15	-	27760321	HL60	viability	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	0.12127541097851213	[221,173]	[149,200]	1	hSpCas9	negative selection	4666952
67646234	67646256	15	+	27760321	HL60	viability	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	-1.5699978611379528	[1,4]	[0,0]	-8	hSpCas9	negative selection	4666953
67580803	67580825	15	+	27760321	HT1080	viability	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.17581419079387528	[136,106]	[94,10]	0	hSpCas9	negative selection	4750412
67586893	67586915	15	+	27760321	HT1080	viability	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.5562121892219833	[238,186]	[35,221]	3	hSpCas9	negative selection	4750413
67600707	67600729	15	+	27760321	HT1080	viability	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	-0.41920288799447825	[412,321]	[108,109]	-2	hSpCas9	negative selection	4750414
67630900	67630922	15	-	27760321	HT1080	viability	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	1.4113800790958622	[173,135]	[253,65]	7	hSpCas9	negative selection	4750415
67646234	67646256	15	+	27760321	HT1080	viability	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	-0.8443172389209588	[4,3]	[0,0]	-4	hSpCas9	negative selection	4750416
67580803	67580825	15	+	27760321	HT29	viability after 7 days	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.18112472615244446	[136,106]	[163,274,94]	2	hSpCas9	negative selection	4833875
67586893	67586915	15	+	27760321	HT29	viability after 7 days	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	-0.6557287122915667	[238,186]	[205,148,170]	-7	hSpCas9	negative selection	4833876
67600707	67600729	15	+	27760321	HT29	viability after 7 days	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	0.4862462746626393	[412,321]	[812,432,756]	7	hSpCas9	negative selection	4833877
67630900	67630922	15	-	27760321	HT29	viability after 7 days	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	0.5752510101511586	[173,135]	[158,390,319]	8	hSpCas9	negative selection	4833878
67646234	67646256	15	+	27760321	HT29	viability after 7 days	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	0.9369001228450724	[4,3]	[34,0,0]	9	hSpCas9	negative selection	4833879
67580803	67580825	15	+	27760321	HT29	viability after 25 days	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	-0.06796081755204941	[136,106]	[136,193,59]	0	hSpCas9	negative selection	4917338
67586893	67586915	15	+	27760321	HT29	viability after 25 days	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	-0.023659055126151518	[238,186]	[289,253,162]	0	hSpCas9	negative selection	4917339
67600707	67600729	15	+	27760321	HT29	viability after 25 days	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	0.08668095464495464	[412,321]	[512,442,368]	0	hSpCas9	negative selection	4917340
67630900	67630922	15	-	27760321	HT29	viability after 25 days	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	0.5680801056960133	[173,135]	[122,309,374]	6	hSpCas9	negative selection	4917341
67646234	67646256	15	+	27760321	HT29	viability after 25 days	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	-2.3639995037674826	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	4917342
67580803	67580825	15	+	27760321	HT29	viability after 22 days	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.390801107079213	[136,106]	[112,228,214]	4	hSpCas9	negative selection	5000801
67586893	67586915	15	+	27760321	HT29	viability after 22 days	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.002176668015281047	[238,186]	[141,224,376]	0	hSpCas9	negative selection	5000802
67600707	67600729	15	+	27760321	HT29	viability after 22 days	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	0.22890918396394183	[412,321]	[507,519,464]	2	hSpCas9	negative selection	5000803
67630900	67630922	15	-	27760321	HT29	viability after 22 days	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	0.967690739052673	[173,135]	[347,296,406]	9	hSpCas9	negative selection	5000804
67646234	67646256	15	+	27760321	HT29	viability after 22 days	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	0.8153574145639189	[4,3]	[24,0,0]	8	hSpCas9	negative selection	5000805
67580803	67580825	15	+	27760321	HT29	viability after 19 days	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	-0.0877701899614114	[136,106]	[264,123,22]	-1	hSpCas9	negative selection	5084264
67586893	67586915	15	+	27760321	HT29	viability after 19 days	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.7848950861551705	[238,186]	[165,257,793]	7	hSpCas9	negative selection	5084265
67600707	67600729	15	+	27760321	HT29	viability after 19 days	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	0.42763267380197095	[412,321]	[703,360,641]	4	hSpCas9	negative selection	5084266
67630900	67630922	15	-	27760321	HT29	viability after 19 days	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	0.5911378255658146	[173,135]	[153,362,271]	6	hSpCas9	negative selection	5084267
67646234	67646256	15	+	27760321	HT29	viability after 19 days	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	-2.365478083203529	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	5084268
67580803	67580825	15	+	27760321	HT29	viability after 16 days	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	-0.138328877540159	[136,106]	[156,129,87]	-1	hSpCas9	negative selection	5167727
67586893	67586915	15	+	27760321	HT29	viability after 16 days	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	-0.12307409673943448	[238,186]	[155,202,291]	-1	hSpCas9	negative selection	5167728
67600707	67600729	15	+	27760321	HT29	viability after 16 days	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	0.1864420647327314	[412,321]	[504,275,630]	2	hSpCas9	negative selection	5167729
67630900	67630922	15	-	27760321	HT29	viability after 16 days	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	0.41409967177903584	[173,135]	[223,290,175]	5	hSpCas9	negative selection	5167730
67646234	67646256	15	+	27760321	HT29	viability after 16 days	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	0.44603459989122385	[4,3]	[19,0,0]	5	hSpCas9	negative selection	5167731
67580803	67580825	15	+	27760321	HT29	viability after 13 days	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.3033375034534107	[136,106]	[169,145,205]	4	hSpCas9	negative selection	5251190
67586893	67586915	15	+	27760321	HT29	viability after 13 days	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.20026909284117367	[238,186]	[394,248,211]	2	hSpCas9	negative selection	5251191
67600707	67600729	15	+	27760321	HT29	viability after 13 days	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	0.17758633818858743	[412,321]	[483,490,471]	2	hSpCas9	negative selection	5251192
67630900	67630922	15	-	27760321	HT29	viability after 13 days	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	-0.11983153796763335	[173,135]	[114,154,222]	-1	hSpCas9	negative selection	5251193
67646234	67646256	15	+	27760321	HT29	viability after 13 days	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	-2.386301030226745	[4,3]	[0,0,0]	-9	hSpCas9	negative selection	5251194
67580803	67580825	15	+	27760321	HT29	viability after 10 days	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.20604867188320353	[136,106]	[149,284,96]	2	hSpCas9	negative selection	5334653
67586893	67586915	15	+	27760321	HT29	viability after 10 days	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	-1.1966350048047683	[238,186]	[119,171,58]	-8	hSpCas9	negative selection	5334654
67600707	67600729	15	+	27760321	HT29	viability after 10 days	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	0.6442045549808415	[412,321]	[828,624,694]	8	hSpCas9	negative selection	5334655
67630900	67630922	15	-	27760321	HT29	viability after 10 days	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	0.15877166553505728	[173,135]	[173,231,241]	2	hSpCas9	negative selection	5334656
67646234	67646256	15	+	27760321	HT29	viability after 10 days	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	-1.741183045360124	[4,3]	[0,0,2]	-9	hSpCas9	negative selection	5334657
67580803	67580825	15	+	27760321	MOLM13	viability	CTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	-0.01906568402126063	[140,136]	[22,123]	0	hSpCas9	negative selection	5418116
67586893	67586915	15	+	27760321	MOLM13	viability	AGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	-0.043710335996678396	[277,238]	[139,141]	0	hSpCas9	negative selection	5418117
67600707	67600729	15	+	27760321	MOLM13	viability	ATCGGGACACTCTTGGTCATGG	MAP2K5	ENSG00000137764	0.7502180218619822	[537,412]	[637,285]	5	hSpCas9	negative selection	5418118
67630900	67630922	15	-	27760321	MOLM13	viability	AGCTAATATTTTCCCACTCGGG	MAP2K5	ENSG00000137764	2.332633836568745	[221,173]	[888,277]	9	hSpCas9	negative selection	5418119
67646234	67646256	15	+	27760321	MOLM13	viability	ATACTACTAGATATTACACTGG	MAP2K5	ENSG00000137764	-1.036070886516221	[1,4]	[0,0]	-6	hSpCas9	negative selection	5418120
67543115	67543138	15	-	27661255	K562	viability	GGGGTCTGAGGTGTCTCCCGGGG	MAP2K5	ENSG00000137764	-0.034890923481498415	[947,1160]	[883,763]	-1	dCas9-KRAB	negative selection	5492066
67543161	67543184	15	-	27661255	K562	viability	GTGATCAGGAACGCACCCGCAGG	MAP2K5	ENSG00000137764	0.5009608249847893	[384,515]	[545,472]	9	dCas9-KRAB	negative selection	5492067
67543243	67543266	15	-	27661255	K562	viability	GAGGTGACAAGGGGAGTGACGGG	MAP2K5	ENSG00000137764	0.08734091729788046	[734,742]	[673,586]	3	dCas9-KRAB	negative selection	5492068
67543253	67543276	15	-	27661255	K562	viability	GGGGCTCCAAGAGGTGACAAGGG	MAP2K5	ENSG00000137764	0.09210210318840505	[704,734]	[624,601]	3	dCas9-KRAB	negative selection	5492069
67585901	67585924	15	-	27260156	BXPC3	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.12769695775095902	[1870]	[2078,2028,1964,2517]	3	hSpCas9	negative selection	5554270
67586892	67586915	15	+	27260156	BXPC3	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.41702657678519706	[713]	[802,943,1167,1105]	8	hSpCas9	negative selection	5554271
67586835	67586858	15	+	27260156	BXPC3	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.27363387768961855	[481]	[645,560,552,678]	6	hSpCas9	negative selection	5554272
67580761	67580784	15	-	27260156	BXPC3	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.06297691697260654	[818]	[826,912,918,922]	1	hSpCas9	negative selection	5618528
67585883	67585906	15	+	27260156	BXPC3	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.01286255708656947	[390]	[357,547,367,363]	0	hSpCas9	negative selection	5618529
67580750	67580773	15	+	27260156	BXPC3	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.09512293003614891	[988]	[964,1054,1185,1240]	2	hSpCas9	negative selection	5618530
67585901	67585924	15	-	27260156	A673	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.05547667048778382	[1870]	[2475,2196,2136,2557]	1	hSpCas9	negative selection	5675521
67586892	67586915	15	+	27260156	A673	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.3946689766914061	[713]	[1469,989,914,1178]	8	hSpCas9	negative selection	5675522
67586835	67586858	15	+	27260156	A673	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.09433648681876547	[481]	[707,690,522,553]	2	hSpCas9	negative selection	5675523
67580761	67580784	15	-	27260156	A673	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.06244921083751509	[818]	[1043,923,911,894]	-1	hSpCas9	negative selection	5739779
67585883	67585906	15	+	27260156	A673	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.20457197661300563	[390]	[366,371,411,477]	-5	hSpCas9	negative selection	5739780
67580750	67580773	15	+	27260156	A673	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.013431729597980002	[988]	[1178,1192,1157,1263]	0	hSpCas9	negative selection	5739781
67585901	67585924	15	-	27260156	A375	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.10991683470179736	[1870]	[2422,2788,2233,2072]	1	hSpCas9	negative selection	5796772
67586892	67586915	15	+	27260156	A375	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.48532067158054204	[713]	[1218,1269,1098,1099]	7	hSpCas9	negative selection	5796773
67586835	67586858	15	+	27260156	A375	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.34979917091751755	[481]	[688,944,644,629]	5	hSpCas9	negative selection	5796774
67580761	67580784	15	-	27260156	A375	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.1832551938094642	[818]	[1480,777,1154,907]	2	hSpCas9	negative selection	5861030
67585883	67585906	15	+	27260156	A375	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.3687226223149667	[390]	[366,865,614,549]	5	hSpCas9	negative selection	5861031
67580750	67580773	15	+	27260156	A375	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.07179618143753363	[988]	[1081,1688,1211,963]	1	hSpCas9	negative selection	5861032
67585901	67585924	15	-	27260156	COLO741	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.1353033182405292	[1870]	[2936,2601,2376]	3	hSpCas9	negative selection	5918023
67586892	67586915	15	+	27260156	COLO741	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.6428333548885385	[713]	[2007,1284,1053]	9	hSpCas9	negative selection	5918024
67586835	67586858	15	+	27260156	COLO741	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.3123661241012854	[481]	[619,818,835]	6	hSpCas9	negative selection	5918025
67580761	67580784	15	-	27260156	COLO741	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.14288052175721866	[818]	[1033,889,925]	-3	hSpCas9	negative selection	5982281
67585883	67585906	15	+	27260156	COLO741	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.26919294747686356	[390]	[519,296,432]	-5	hSpCas9	negative selection	5982282
67580750	67580773	15	+	27260156	COLO741	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.12855429045779787	[988]	[2065,1059,1093]	2	hSpCas9	negative selection	5982283
67585901	67585924	15	-	27260156	CAL120	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.36849232016037736	[1870]	[3792,2697,2649]	5	hSpCas9	negative selection	6039274
67586892	67586915	15	+	27260156	CAL120	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.710375752697104	[713]	[1748,1249,1406]	9	hSpCas9	negative selection	6039275
67586835	67586858	15	+	27260156	CAL120	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.21538239918030014	[481]	[613,965,499]	3	hSpCas9	negative selection	6039276
67580761	67580784	15	-	27260156	CAL120	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.3661061328671349	[818]	[1368,1295,1283]	5	hSpCas9	negative selection	6103532
67585883	67585906	15	+	27260156	CAL120	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.3780639436570797	[390]	[330,383,400]	-5	hSpCas9	negative selection	6103533
67580750	67580773	15	+	27260156	CAL120	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.3243065726167842	[988]	[2122,1063,1522]	5	hSpCas9	negative selection	6103534
67585901	67585924	15	-	27260156	CADOES1	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.1372125101781887	[1870]	[1816,1687,1898,2263]	2	hSpCas9	negative selection	6160525
67586892	67586915	15	+	27260156	CADOES1	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.3337811947222603	[713]	[773,771,956,844]	5	hSpCas9	negative selection	6160526
67586835	67586858	15	+	27260156	CADOES1	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.3137415892932782	[481]	[486,684,479,577]	5	hSpCas9	negative selection	6160527
67580761	67580784	15	-	27260156	CADOES1	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.017420984408130002	[818]	[971,734,562,814]	0	hSpCas9	negative selection	6224783
67585883	67585906	15	+	27260156	CADOES1	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.3433493635733467	[390]	[241,594,554,453]	6	hSpCas9	negative selection	6224784
67580750	67580773	15	+	27260156	CADOES1	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.05682182941319991	[988]	[1050,779,1039,656]	-1	hSpCas9	negative selection	6224785
67585901	67585924	15	-	27260156	EWS502	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.039977111975682655	[1870]	[1700,2168,2295,2012]	0	hSpCas9	negative selection	6281776
67586892	67586915	15	+	27260156	EWS502	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.38570997620074554	[713]	[749,1095,818,1329]	6	hSpCas9	negative selection	6281777
67586835	67586858	15	+	27260156	EWS502	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.26462835095839987	[481]	[611,601,601,636]	4	hSpCas9	negative selection	6281778
67580761	67580784	15	-	27260156	EWS502	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.49134484469534945	[818]	[848,921,1873,1299]	8	hSpCas9	negative selection	6346034
67585883	67585906	15	+	27260156	EWS502	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.03485461365008291	[390]	[375,419,440,379]	0	hSpCas9	negative selection	6346035
67580750	67580773	15	+	27260156	EWS502	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.11068738986941029	[988]	[1100,1140,914,1380]	2	hSpCas9	negative selection	6346036
67585901	67585924	15	-	27260156	EW8	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	-0.09134881562880293	[1870]	[1645,1416,1188,1500]	-2	hSpCas9	negative selection	6403027
67586892	67586915	15	+	27260156	EW8	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.7322492488914012	[713]	[871,705,1441,729]	9	hSpCas9	negative selection	6403028
67586835	67586858	15	+	27260156	EW8	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.32086500660700046	[481]	[479,617,375,494]	6	hSpCas9	negative selection	6403029
67580761	67580784	15	-	27260156	EW8	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.016685065738508476	[818]	[753,671,365,889]	0	hSpCas9	negative selection	6467285
67585883	67585906	15	+	27260156	EW8	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.35645538651016073	[390]	[417,376,361,472]	6	hSpCas9	negative selection	6467286
67580750	67580773	15	+	27260156	EW8	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.008933347568142569	[988]	[1110,803,661,704]	0	hSpCas9	negative selection	6467287
67585901	67585924	15	-	27260156	CORL105	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.2302152838002336	[1870]	[2779,2377,2910,2272]	4	hSpCas9	negative selection	6524278
67586892	67586915	15	+	27260156	CORL105	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.5334923576725377	[713]	[1183,1063,1401,1220]	8	hSpCas9	negative selection	6524279
67586835	67586858	15	+	27260156	CORL105	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.20358788418952034	[481]	[652,509,810,652]	4	hSpCas9	negative selection	6524280
67580761	67580784	15	-	27260156	CORL105	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.08068654634717476	[818]	[829,897,1456,935]	1	hSpCas9	negative selection	6588536
67585883	67585906	15	+	27260156	CORL105	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.06937644730930825	[390]	[444,485,426,552]	1	hSpCas9	negative selection	6588537
67580750	67580773	15	+	27260156	CORL105	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.05188321265758322	[988]	[1115,1177,1315,1205]	1	hSpCas9	negative selection	6588538
67585901	67585924	15	-	27260156	HS294T	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	-0.1961091015976384	[1870]	[558,653,595,738]	-3	hSpCas9	negative selection	6645529
67586892	67586915	15	+	27260156	HS294T	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.5535397544633467	[713]	[417,479,344,365]	7	hSpCas9	negative selection	6645530
67586835	67586858	15	+	27260156	HS294T	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.2804288882547813	[481]	[225,282,135,263]	4	hSpCas9	negative selection	6645531
67580761	67580784	15	-	27260156	HS294T	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.3482087127644731	[818]	[202,249,229,328]	-5	hSpCas9	negative selection	6709787
67585883	67585906	15	+	27260156	HS294T	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.3166819875516713	[390]	[122,149,194,312]	4	hSpCas9	negative selection	6709788
67580750	67580773	15	+	27260156	HS294T	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.007634077040772569	[988]	[293,363,501,366]	0	hSpCas9	negative selection	6709789
67585901	67585924	15	-	27260156	HCC44	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.005139324690553115	[1870]	[2533,2083,2116,1794]	0	hSpCas9	negative selection	6766780
67586892	67586915	15	+	27260156	HCC44	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.3533880715420715	[713]	[873,792,1409,1122]	6	hSpCas9	negative selection	6766781
67586835	67586858	15	+	27260156	HCC44	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.1331209528925114	[481]	[584,484,843,531]	2	hSpCas9	negative selection	6766782
67580761	67580784	15	-	27260156	HCC44	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.15857870144922293	[818]	[1103,714,994,576]	-3	hSpCas9	negative selection	6831038
67585883	67585906	15	+	27260156	HCC44	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.22083360651745088	[390]	[618,326,661,510]	3	hSpCas9	negative selection	6831039
67580750	67580773	15	+	27260156	HCC44	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.20600018303041656	[988]	[1012,827,907,1129]	-3	hSpCas9	negative selection	6831040
67585901	67585924	15	-	27260156	G402	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.1724166847452484	[1870]	[3222,2364,2518,2270]	2	hSpCas9	negative selection	6888031
67586892	67586915	15	+	27260156	G402	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.5532617385477956	[713]	[1498,1244,1207,1190]	7	hSpCas9	negative selection	6888032
67586835	67586858	15	+	27260156	G402	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	1.0457786145975116	[481]	[1561,946,1655,744]	9	hSpCas9	negative selection	6888033
67580761	67580784	15	-	27260156	G402	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.05600069095712157	[818]	[1228,796,934,911]	0	hSpCas9	negative selection	6952289
67585883	67585906	15	+	27260156	G402	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.3417753716693256	[390]	[742,751,265,679]	4	hSpCas9	negative selection	6952290
67580750	67580773	15	+	27260156	G402	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.046068512053635935	[988]	[1718,1043,1079,1194]	0	hSpCas9	negative selection	6952291
67585901	67585924	15	-	27260156	L33	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.033248954367066874	[1870]	[1916,728,1177,2085]	0	hSpCas9	negative selection	7009282
67586892	67586915	15	+	27260156	L33	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.5816263432450173	[713]	[1100,428,673,1052]	9	hSpCas9	negative selection	7009283
67586835	67586858	15	+	27260156	L33	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.057175231685118774	[481]	[455,200,303,575]	1	hSpCas9	negative selection	7009284
67580761	67580784	15	-	27260156	L33	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.20890141593350653	[818]	[858,297,428,562]	-5	hSpCas9	negative selection	7073540
67585883	67585906	15	+	27260156	L33	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.129643148438841	[390]	[316,164,201,388]	-3	hSpCas9	negative selection	7073541
67580750	67580773	15	+	27260156	L33	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.039261147960143905	[988]	[902,408,634,1154]	0	hSpCas9	negative selection	7073542
67585901	67585924	15	-	27260156	K562	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	-0.09169787757692482	[1870]	[1486,1574,1629,1531]	-1	hSpCas9	negative selection	7130533
67586892	67586915	15	+	27260156	K562	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.4620065098733499	[713]	[1027,1426,519,587]	6	hSpCas9	negative selection	7130534
67586835	67586858	15	+	27260156	K562	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.36702354143612814	[481]	[476,627,562,535]	4	hSpCas9	negative selection	7130535
67580761	67580784	15	-	27260156	K562	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.17484921110747764	[818]	[902,650,739,964]	2	hSpCas9	negative selection	7194791
67585883	67585906	15	+	27260156	K562	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.19464507848848916	[390]	[401,234,651,300]	2	hSpCas9	negative selection	7194792
67580750	67580773	15	+	27260156	K562	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.12922578978760324	[988]	[1243,804,646,1133]	1	hSpCas9	negative selection	7194793
67585901	67585924	15	-	27260156	HT29	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.11473427775591172	[1870]	[2288,2484,2617,2432]	2	hSpCas9	negative selection	7251784
67586892	67586915	15	+	27260156	HT29	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.3055875053641115	[713]	[980,1137,1290,893]	6	hSpCas9	negative selection	7251785
67586835	67586858	15	+	27260156	HT29	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.3976708604278236	[481]	[940,718,744,694]	7	hSpCas9	negative selection	7251786
67580761	67580784	15	-	27260156	HT29	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.07902363414506397	[818]	[1173,1205,1152,728]	1	hSpCas9	negative selection	7316042
67585883	67585906	15	+	27260156	HT29	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.08116933992539205	[390]	[414,632,523,446]	1	hSpCas9	negative selection	7316043
67580750	67580773	15	+	27260156	HT29	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.2589102063750084	[988]	[1281,1893,1453,1173]	5	hSpCas9	negative selection	7316044
67585901	67585924	15	-	27260156	MHHES1	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.187022426383334	[1870]	[2290,2902,2690,1829]	3	hSpCas9	negative selection	7373035
67586892	67586915	15	+	27260156	MHHES1	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.4363666414668985	[713]	[1435,916,1001,1013]	7	hSpCas9	negative selection	7373036
67586835	67586858	15	+	27260156	MHHES1	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.329018454260416	[481]	[719,1125,521,447]	6	hSpCas9	negative selection	7373037
67580761	67580784	15	-	27260156	MHHES1	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.25026786514915633	[818]	[1273,1351,1177,700]	4	hSpCas9	negative selection	7437293
67585883	67585906	15	+	27260156	MHHES1	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.14309454717239287	[390]	[740,391,531,327]	2	hSpCas9	negative selection	7437294
67580750	67580773	15	+	27260156	MHHES1	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.1755113808038844	[988]	[1441,1585,1189,919]	3	hSpCas9	negative selection	7437295
67585901	67585924	15	-	27260156	MEWO	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.06377957538807144	[1870]	[2287,1640,1648]	1	hSpCas9	negative selection	7494286
67586892	67586915	15	+	27260156	MEWO	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.3128603303246912	[713]	[932,847,727]	6	hSpCas9	negative selection	7494287
67586835	67586858	15	+	27260156	MEWO	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.04594206958332592	[481]	[606,444,371]	1	hSpCas9	negative selection	7494288
67580761	67580784	15	-	27260156	MEWO	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.01693353195628078	[818]	[866,744,680]	0	hSpCas9	negative selection	7558544
67585883	67585906	15	+	27260156	MEWO	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.07886554763818768	[390]	[416,370,376]	1	hSpCas9	negative selection	7558545
67580750	67580773	15	+	27260156	MEWO	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.17403904835096684	[988]	[1085,967,1085]	4	hSpCas9	negative selection	7558546
67585901	67585924	15	-	27260156	LNCAPCLONEFGC	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.13875768918917308	[1870]	[1939,1730,1905,1898]	2	hSpCas9	negative selection	7615537
67586892	67586915	15	+	27260156	LNCAPCLONEFGC	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.31892394107924593	[713]	[783,700,866,890]	5	hSpCas9	negative selection	7615538
67586835	67586858	15	+	27260156	LNCAPCLONEFGC	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.39566042568911897	[481]	[607,621,591,473]	6	hSpCas9	negative selection	7615539
67580761	67580784	15	-	27260156	LNCAPCLONEFGC	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.12473094226303716	[818]	[613,626,611,862]	-2	hSpCas9	negative selection	7679795
67585883	67585906	15	+	27260156	LNCAPCLONEFGC	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.222335939410235	[390]	[271,350,298,288]	-4	hSpCas9	negative selection	7679796
67580750	67580773	15	+	27260156	LNCAPCLONEFGC	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.10723861245954303	[988]	[1077,637,1093,1087]	1	hSpCas9	negative selection	7679797
67585901	67585924	15	-	27260156	PANC0327	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.06543359599693122	[1870]	[1808,1563,1616,1993]	0	hSpCas9	negative selection	7736788
67586892	67586915	15	+	27260156	PANC0327	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.33424495932886833	[713]	[807,905,694,775]	5	hSpCas9	negative selection	7736789
67586835	67586858	15	+	27260156	PANC0327	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.6925465652820209	[481]	[912,416,596,893]	8	hSpCas9	negative selection	7736790
67580761	67580784	15	-	27260156	PANC0327	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.21096740934104286	[818]	[653,628,604,627]	-3	hSpCas9	negative selection	7801046
67585883	67585906	15	+	27260156	PANC0327	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.19217522982263469	[390]	[446,297,405,452]	3	hSpCas9	negative selection	7801047
67580750	67580773	15	+	27260156	PANC0327	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.24458048496562024	[988]	[1110,417,751,756]	-4	hSpCas9	negative selection	7801048
67585901	67585924	15	-	27260156	NCIH2009	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.27480202110904917	[1870]	[3675,2769,3144]	4	hSpCas9	negative selection	7858039
67586892	67586915	15	+	27260156	NCIH2009	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.36625651839493467	[713]	[1606,894,1423]	5	hSpCas9	negative selection	7858040
67586835	67586858	15	+	27260156	NCIH2009	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.30708678769730613	[481]	[906,650,957]	4	hSpCas9	negative selection	7858041
67580761	67580784	15	-	27260156	NCIH2009	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.05703056291790809	[818]	[1587,1064,741]	-1	hSpCas9	negative selection	7922297
67585883	67585906	15	+	27260156	NCIH2009	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.1009256554895136	[390]	[577,389,574]	-1	hSpCas9	negative selection	7922298
67580750	67580773	15	+	27260156	NCIH2009	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.015285630700589081	[988]	[1516,1419,1190]	0	hSpCas9	negative selection	7922299
67585901	67585924	15	-	27260156	NCIH1373	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.17188563431762982	[1870]	[2538,1902,2376,713]	1	hSpCas9	negative selection	7979290
67586892	67586915	15	+	27260156	NCIH1373	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	1.1395799981832742	[713]	[2691,1527,1704,330]	9	hSpCas9	negative selection	7979291
67586835	67586858	15	+	27260156	NCIH1373	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	1.2083705351183305	[481]	[1795,1084,1379,209]	9	hSpCas9	negative selection	7979292
67580761	67580784	15	-	27260156	NCIH1373	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.19829429924603104	[818]	[1340,1027,657,327]	2	hSpCas9	negative selection	8043548
67585883	67585906	15	+	27260156	NCIH1373	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.19101383926405657	[390]	[535,390,598,127]	1	hSpCas9	negative selection	8043549
67580750	67580773	15	+	27260156	NCIH1373	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.4608823380981385	[988]	[978,808,872,148]	-4	hSpCas9	negative selection	8043550
67585901	67585924	15	-	27260156	PATU8902	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.11670324534016596	[1870]	[1776,3368,2487,3872]	1	hSpCas9	negative selection	8100541
67586892	67586915	15	+	27260156	PATU8902	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.6072219741862406	[713]	[1323,1898,1215,1712]	6	hSpCas9	negative selection	8100542
67586835	67586858	15	+	27260156	PATU8902	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.6436094888568488	[481]	[1284,869,735,1416]	6	hSpCas9	negative selection	8100543
67580761	67580784	15	-	27260156	PATU8902	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.29260895919811647	[818]	[1395,1169,1602,1347]	3	hSpCas9	negative selection	8164799
67585883	67585906	15	+	27260156	PATU8902	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.4307672242655014	[390]	[759,820,814,482]	4	hSpCas9	negative selection	8164800
67580750	67580773	15	+	27260156	PATU8902	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.21656413596706647	[988]	[1243,1234,1032,1268]	-2	hSpCas9	negative selection	8164801
67585901	67585924	15	-	27260156	PANC1	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	-0.010633689406558844	[1870]	[1365,2341,1336,1483]	0	hSpCas9	negative selection	8221792
67586892	67586915	15	+	27260156	PANC1	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.7574525193101336	[713]	[1006,1175,1130,872]	9	hSpCas9	negative selection	8221793
67586835	67586858	15	+	27260156	PANC1	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.5758297483474609	[481]	[692,793,474,541]	8	hSpCas9	negative selection	8221794
67580761	67580784	15	-	27260156	PANC1	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.15575750505234354	[818]	[867,1148,672,543]	2	hSpCas9	negative selection	8286050
67585883	67585906	15	+	27260156	PANC1	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.23953072520745805	[390]	[254,427,211,269]	-4	hSpCas9	negative selection	8286051
67580750	67580773	15	+	27260156	PANC1	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.03355105939829173	[988]	[934,1135,744,589]	0	hSpCas9	negative selection	8286052
67585901	67585924	15	-	27260156	PANC0813	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.2861143807160216	[1870]	[2912,2183,3010,2632]	4	hSpCas9	negative selection	8343043
67586892	67586915	15	+	27260156	PANC0813	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.6549580736094409	[713]	[1069,1653,1447,1097]	9	hSpCas9	negative selection	8343044
67586835	67586858	15	+	27260156	PANC0813	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.5749026387971523	[481]	[750,1091,906,625]	8	hSpCas9	negative selection	8343045
67580761	67580784	15	-	27260156	PANC0813	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.07620535953273344	[818]	[1051,1022,890,706]	-1	hSpCas9	negative selection	8407301
67585883	67585906	15	+	27260156	PANC0813	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.09947351973517088	[390]	[392,495,589,242]	-2	hSpCas9	negative selection	8407302
67580750	67580773	15	+	27260156	PANC0813	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.036439092035072784	[988]	[1089,1148,1200,1087]	0	hSpCas9	negative selection	8407303
67585901	67585924	15	-	27260156	RDES	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.21370350280741923	[1870]	[2052,2150,2340,3662]	3	hSpCas9	negative selection	8464294
67586892	67586915	15	+	27260156	RDES	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.4430288406938605	[713]	[957,1109,1123,1300]	7	hSpCas9	negative selection	8464295
67586835	67586858	15	+	27260156	RDES	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.471964093524995	[481]	[522,937,914,709]	7	hSpCas9	negative selection	8464296
67580761	67580784	15	-	27260156	RDES	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.08080030491667367	[818]	[573,932,1154,960]	-1	hSpCas9	negative selection	8528552
67585883	67585906	15	+	27260156	RDES	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.1013269920665012	[390]	[393,499,409,650]	1	hSpCas9	negative selection	8528553
67580750	67580773	15	+	27260156	RDES	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.045540730334436175	[988]	[905,1128,1242,1496]	0	hSpCas9	negative selection	8528554
67585901	67585924	15	-	27260156	PC3	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.03200554667216449	[1870]	[1271,1783,3084,2039]	0	hSpCas9	negative selection	8585545
67586892	67586915	15	+	27260156	PC3	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.5157112042330263	[713]	[472,1103,1411,1407]	9	hSpCas9	negative selection	8585546
67586835	67586858	15	+	27260156	PC3	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.06341102545925445	[481]	[258,491,897,582]	1	hSpCas9	negative selection	8585547
67580761	67580784	15	-	27260156	PC3	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.2716120878359446	[818]	[549,617,1102,570]	-6	hSpCas9	negative selection	8649803
67585883	67585906	15	+	27260156	PC3	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.41815816774624376	[390]	[147,370,486,269]	-7	hSpCas9	negative selection	8649804
67580750	67580773	15	+	27260156	PC3	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.045684308559676534	[988]	[573,1065,1511,1219]	1	hSpCas9	negative selection	8649805
67585901	67585924	15	-	27260156	PATU8988T	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.06082247006258856	[1870]	[1949,1914,1725,1962]	1	hSpCas9	negative selection	8706796
67586892	67586915	15	+	27260156	PATU8988T	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.8035578756384609	[713]	[1332,943,1180,1345]	9	hSpCas9	negative selection	8706797
67586835	67586858	15	+	27260156	PATU8988T	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.19722536803559304	[481]	[413,593,476,667]	3	hSpCas9	negative selection	8706798
67580761	67580784	15	-	27260156	PATU8988T	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.13041567092268447	[818]	[682,1085,1003,696]	2	hSpCas9	negative selection	8771054
67585883	67585906	15	+	27260156	PATU8988T	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.28801002341107357	[390]	[763,300,308,457]	5	hSpCas9	negative selection	8771055
67580750	67580773	15	+	27260156	PATU8988T	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.06955482640828503	[988]	[925,1156,1014,920]	1	hSpCas9	negative selection	8771056
67585901	67585924	15	-	27260156	T47D	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.07073672632861405	[1870]	[2244,2246,2360,2305]	1	hSpCas9	negative selection	8828047
67586892	67586915	15	+	27260156	T47D	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.5701133695491036	[713]	[1206,1121,1314,1305]	9	hSpCas9	negative selection	8828048
67586835	67586858	15	+	27260156	T47D	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.33801401330476744	[481]	[757,679,691,711]	7	hSpCas9	negative selection	8828049
67580761	67580784	15	-	27260156	T47D	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.04262440620987529	[818]	[963,885,985,869]	-1	hSpCas9	negative selection	8892305
67585883	67585906	15	+	27260156	T47D	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.017897605910973113	[390]	[421,492,447,431]	0	hSpCas9	negative selection	8892306
67580750	67580773	15	+	27260156	T47D	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.06386062148274219	[988]	[1358,1099,1188,1177]	1	hSpCas9	negative selection	8892307
67585901	67585924	15	-	27260156	SU8686	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.19562825601021916	[1870]	[1937,1757,2050,2932]	3	hSpCas9	negative selection	8949298
67586892	67586915	15	+	27260156	SU8686	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.7780641035625213	[713]	[974,1407,1230,1238]	9	hSpCas9	negative selection	8949299
67586835	67586858	15	+	27260156	SU8686	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.42336832055773443	[481]	[706,512,674,679]	7	hSpCas9	negative selection	8949300
67580761	67580784	15	-	27260156	SU8686	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.059198124685017284	[818]	[754,686,789,916]	-1	hSpCas9	negative selection	9013556
67585883	67585906	15	+	27260156	SU8686	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.28768375254443207	[390]	[282,272,450,265]	-5	hSpCas9	negative selection	9013557
67580750	67580773	15	+	27260156	SU8686	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.2373738787888635	[988]	[999,1122,1231,1308]	4	hSpCas9	negative selection	9013558
67585901	67585924	15	-	27260156	SKES1	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.17477771598621028	[1870]	[2542,2194,2021,1758]	4	hSpCas9	negative selection	9070549
67586892	67586915	15	+	27260156	SKES1	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.47250341494261905	[713]	[957,1325,911,805]	8	hSpCas9	negative selection	9070550
67586835	67586858	15	+	27260156	SKES1	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.25288455095576834	[481]	[680,695,428,517]	5	hSpCas9	negative selection	9070551
67580761	67580784	15	-	27260156	SKES1	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.09508984944708188	[818]	[767,765,1038,877]	2	hSpCas9	negative selection	9134807
67585883	67585906	15	+	27260156	SKES1	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.25928356146884735	[390]	[674,523,409,308]	5	hSpCas9	negative selection	9134808
67580750	67580773	15	+	27260156	SKES1	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.013367121894119594	[988]	[1011,1141,966,821]	0	hSpCas9	negative selection	9134809
67585901	67585924	15	-	27260156	TOV112D	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.15760362072665335	[1870]	[2145,2473,1944,1896]	3	hSpCas9	negative selection	9191800
67586892	67586915	15	+	27260156	TOV112D	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.29753848861518006	[713]	[1011,1094,790,685]	5	hSpCas9	negative selection	9191801
67586835	67586858	15	+	27260156	TOV112D	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.26006083573687566	[481]	[378,787,624,554]	5	hSpCas9	negative selection	9191802
67580761	67580784	15	-	27260156	TOV112D	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.05039923898450527	[818]	[1022,1242,618,422]	-1	hSpCas9	negative selection	9256058
67585883	67585906	15	+	27260156	TOV112D	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.3566959353335241	[390]	[391,233,266,318]	-6	hSpCas9	negative selection	9256059
67580750	67580773	15	+	27260156	TOV112D	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	-0.03264385878514342	[988]	[1011,1353,981,631]	0	hSpCas9	negative selection	9256060
67585901	67585924	15	-	27260156	TC71	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.03450348361335531	[1870]	[2189,1934,1825,2283]	0	hSpCas9	negative selection	9313051
67586892	67586915	15	+	27260156	TC71	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.4594749502223996	[713]	[903,1017,1221,1063]	9	hSpCas9	negative selection	9313052
67586835	67586858	15	+	27260156	TC71	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.06966336289309855	[481]	[474,488,575,634]	1	hSpCas9	negative selection	9313053
67580761	67580784	15	-	27260156	TC71	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.10746542652706681	[818]	[783,878,924,658]	-3	hSpCas9	negative selection	9377309
67585883	67585906	15	+	27260156	TC71	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	-0.00587762023660543	[390]	[427,454,399,384]	0	hSpCas9	negative selection	9377310
67580750	67580773	15	+	27260156	TC71	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.1076845160269928	[988]	[1197,1201,905,1277]	2	hSpCas9	negative selection	9377311
67585901	67585924	15	-	27260156	TC32	viability	CCATGTATGTTCCGTTCCCCAGG	MAP2K5	ENSG00000137764	0.30384147866677647	[1870]	[1975,1600,2756,2584]	5	hSpCas9	negative selection	9434302
67586892	67586915	15	+	27260156	TC32	viability	CAGATTCACTTCCAAGCAATAGG	MAP2K5	ENSG00000137764	0.5511491380663942	[713]	[968,696,1253,1118]	8	hSpCas9	negative selection	9434303
67586835	67586858	15	+	27260156	TC32	viability	TTTACTTATAGGTGAATACTCGG	MAP2K5	ENSG00000137764	0.4012260645102945	[481]	[417,627,787,562]	7	hSpCas9	negative selection	9434304
67580761	67580784	15	-	27260156	TC32	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.02787914996549745	[818]	[741,614,827,860]	0	hSpCas9	negative selection	9498560
67585883	67585906	15	+	27260156	TC32	viability	GTTTCAGCCTGCAAGCCTCCTGG	MAP2K5	ENSG00000137764	0.17108915140182612	[390]	[331,376,546,420]	3	hSpCas9	negative selection	9498561
67580750	67580773	15	+	27260156	TC32	viability	GCAGTATTATTCCACAGTAATGG	MAP2K5	ENSG00000137764	0.21650716057135755	[988]	[846,824,1697,1122]	4	hSpCas9	negative selection	9498562
67543439	67543462	15	-	27869803	HPAFII	viability after 27 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	0.33764681150427833	[184]	[195,61,NaN]	2	hSpCas9	negative selection	9554470
67586840	67586863	15	+	27869803	HPAFII	viability after 27 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.7957549253738112	[165]	[52,47,NaN]	-5	hSpCas9	negative selection	9554471
67600715	67600738	15	+	27869803	HPAFII	viability after 27 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	0.1447756716472709	[436]	[229,273,NaN]	1	hSpCas9	negative selection	9554472
67692498	67692521	15	+	27869803	HPAFII	viability after 27 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.7911694676267803	[131]	[70,160,NaN]	6	hSpCas9	negative selection	9554473
67727912	67727935	15	-	27869803	HPAFII	viability after 27 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.2507567868828089	[128]	[50,61,NaN]	-2	hSpCas9	negative selection	9554474
67748574	67748597	15	-	27869803	HPAFII	viability after 27 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.5431387315085809	[409]	[384,254,NaN]	4	hSpCas9	negative selection	9554475
67543439	67543462	15	-	27869803	HPAFII	viability after 15 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	0.07748110487121429	[184]	[157,241,NaN]	0	hSpCas9	negative selection	9636919
67586840	67586863	15	+	27869803	HPAFII	viability after 15 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-1.2033827357135176	[165]	[148,32,NaN]	-8	hSpCas9	negative selection	9636920
67600715	67600738	15	+	27869803	HPAFII	viability after 15 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-0.22997716913685018	[436]	[598,276,NaN]	-3	hSpCas9	negative selection	9636921
67692498	67692521	15	+	27869803	HPAFII	viability after 15 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.9871278899100897	[131]	[369,225,NaN]	9	hSpCas9	negative selection	9636922
67727912	67727935	15	-	27869803	HPAFII	viability after 15 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	0.22914142516175318	[128]	[217,127,NaN]	2	hSpCas9	negative selection	9636923
67748574	67748597	15	-	27869803	HPAFII	viability after 15 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.5196930262479924	[409]	[693,592,NaN]	6	hSpCas9	negative selection	9636924
67543439	67543462	15	-	27869803	ASPC1	viability after 36 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-0.32477386632036553	[417]	[43,93,183]	-3	hSpCas9	negative selection	9719368
67586840	67586863	15	+	27869803	ASPC1	viability after 36 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.9877920363969042	[479]	[168,99,11]	-7	hSpCas9	negative selection	9719369
67600715	67600738	15	+	27869803	ASPC1	viability after 36 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-0.3298295602015756	[1007]	[50,572,204]	-3	hSpCas9	negative selection	9719370
67692498	67692521	15	+	27869803	ASPC1	viability after 36 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-0.5039961169708684	[358]	[186,65,35]	-5	hSpCas9	negative selection	9719371
67727912	67727935	15	-	27869803	ASPC1	viability after 36 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.7548065541843849	[439]	[51,15,176]	-6	hSpCas9	negative selection	9719372
67748574	67748597	15	-	27869803	ASPC1	viability after 36 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.6777068613492592	[920]	[384,325,748]	6	hSpCas9	negative selection	9719373
67543439	67543462	15	-	27869803	PATU8988S	viability after 35 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	0.33182638838351636	[357]	[168,193,NaN]	4	hSpCas9	negative selection	9801817
67586840	67586863	15	+	27869803	PATU8988S	viability after 35 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	0.3571831253354632	[318]	[194,133,NaN]	4	hSpCas9	negative selection	9801818
67600715	67600738	15	+	27869803	PATU8988S	viability after 35 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	0.2225753392374098	[938]	[558,322,NaN]	2	hSpCas9	negative selection	9801819
67692498	67692521	15	+	27869803	PATU8988S	viability after 35 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.39669314530717714	[360]	[150,231,NaN]	4	hSpCas9	negative selection	9801820
67727912	67727935	15	-	27869803	PATU8988S	viability after 35 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.5355541120484766	[321]	[75,102,NaN]	-5	hSpCas9	negative selection	9801821
67748574	67748597	15	-	27869803	PATU8988S	viability after 35 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.8863151184259567	[796]	[740,444,NaN]	8	hSpCas9	negative selection	9801822
67543439	67543462	15	-	27869803	PATU8988S	viability after 31 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	0.8106846801167211	[357]	[201,311,NaN]	8	hSpCas9	negative selection	9884266
67586840	67586863	15	+	27869803	PATU8988S	viability after 31 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.20012965590999543	[318]	[126,89,NaN]	-2	hSpCas9	negative selection	9884267
67600715	67600738	15	+	27869803	PATU8988S	viability after 31 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	0.18239685214407475	[938]	[423,425,NaN]	2	hSpCas9	negative selection	9884268
67692498	67692521	15	+	27869803	PATU8988S	viability after 31 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.2916599986236681	[360]	[162,192,NaN]	3	hSpCas9	negative selection	9884269
67727912	67727935	15	-	27869803	PATU8988S	viability after 31 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-1.2231494546811559	[321]	[43,68,NaN]	-8	hSpCas9	negative selection	9884270
67748574	67748597	15	-	27869803	PATU8988S	viability after 31 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	1.0121352678194855	[796]	[669,603,NaN]	9	hSpCas9	negative selection	9884271
67543439	67543462	15	-	27869803	HPAFII	viability after 35 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-1.1153570390003442	[184]	[30,56,NaN]	-6	hSpCas9	negative selection	9966715
67586840	67586863	15	+	27869803	HPAFII	viability after 35 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.2783237811116843	[165]	[65,72,NaN]	-2	hSpCas9	negative selection	9966716
67600715	67600738	15	+	27869803	HPAFII	viability after 35 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	-0.04399562778158694	[436]	[207,221,NaN]	0	hSpCas9	negative selection	9966717
67692498	67692521	15	+	27869803	HPAFII	viability after 35 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	1.5031314627646726	[131]	[84,306,NaN]	8	hSpCas9	negative selection	9966718
67727912	67727935	15	-	27869803	HPAFII	viability after 35 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	0.32548962487161837	[128]	[102,57,NaN]	2	hSpCas9	negative selection	9966719
67748574	67748597	15	-	27869803	HPAFII	viability after 35 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.8148765702692333	[409]	[271,469,NaN]	5	hSpCas9	negative selection	9966720
67543439	67543462	15	-	27869803	HPAFII	viability after 31 days	CCTGAAGAGTAACTGCGGCCCGG	MAP2K5	ENSG00000137764	-0.011709843934998354	[184]	[124,78,NaN]	0	hSpCas9	negative selection	10049164
67586840	67586863	15	+	27869803	HPAFII	viability after 31 days	TTATAGGTGAATACTCGGGCCGG	MAP2K5	ENSG00000137764	-0.3517025157991306	[165]	[61,84,NaN]	-2	hSpCas9	negative selection	10049165
67600715	67600738	15	+	27869803	HPAFII	viability after 31 days	ACTCTTGGTCATGGCAACGGAGG	MAP2K5	ENSG00000137764	0.2027845192208253	[436]	[276,287,NaN]	1	hSpCas9	negative selection	10049166
67692498	67692521	15	+	27869803	HPAFII	viability after 31 days	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	1.0865484620669759	[131]	[130,185,NaN]	7	hSpCas9	negative selection	10049167
67727912	67727935	15	-	27869803	HPAFII	viability after 31 days	GAAACCTCCCAAGAGCAAGCTGG	MAP2K5	ENSG00000137764	-0.1679075019736096	[128]	[51,77,NaN]	-1	hSpCas9	negative selection	10049168
67748574	67748597	15	-	27869803	HPAFII	viability after 31 days	CAACAATGCACTGCAGAAGCTGG	MAP2K5	ENSG00000137764	0.5157409046024446	[409]	[294,365,NaN]	4	hSpCas9	negative selection	10049169
67703333	67703356	15	+	28162770	P31FUJ	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	0.1760033411529507	[173]	[230]	1	hSpCas9	negative selection	10188687
67692498	67692521	15	+	28162770	P31FUJ	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.8062976152745616	[90]	[186]	8	hSpCas9	negative selection	10188688
67563314	67563337	15	+	28162770	P31FUJ	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.1453592926294326	[316]	[411]	1	hSpCas9	negative selection	10188689
67580761	67580784	15	-	28162770	P31FUJ	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.16044508951541858	[516]	[678]	1	hSpCas9	negative selection	10188690
67580802	67580825	15	+	28162770	P31FUJ	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.3104235640339551	[338]	[493]	3	hSpCas9	negative selection	10188691
67600712	67600735	15	+	28162770	P31FUJ	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	-0.21333234021615377	[367]	[372]	-2	hSpCas9	negative selection	10188692
67769602	67769625	15	+	28162770	P31FUJ	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	-0.0014766583079228734	[505]	[593]	0	hSpCas9	negative selection	10188693
67769609	67769632	15	-	28162770	P31FUJ	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	0.307766176948324	[76]	[111]	3	hSpCas9	negative selection	10188694
67585909	67585932	15	+	28162770	P31FUJ	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	0.38963500172544063	[455]	[701]	4	hSpCas9	negative selection	10188695
67630886	67630909	15	+	28162770	P31FUJ	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.3786325076679684	[467]	[714]	4	hSpCas9	negative selection	10188696
67703333	67703356	15	+	28162770	TF1	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10358053
67692498	67692521	15	+	28162770	TF1	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10358054
67563314	67563337	15	+	28162770	TF1	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	NaN	[NaN]	[349]	1	hSpCas9	negative selection	10358055
67580761	67580784	15	-	28162770	TF1	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	NaN	[NaN]	[373]	1	hSpCas9	negative selection	10358056
67580802	67580825	15	+	28162770	TF1	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	NaN	[NaN]	[405]	1	hSpCas9	negative selection	10358057
67600712	67600735	15	+	28162770	TF1	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	NaN	[NaN]	[300]	1	hSpCas9	negative selection	10358058
67769602	67769625	15	+	28162770	TF1	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	NaN	[NaN]	[181]	1	hSpCas9	negative selection	10358059
67769609	67769632	15	-	28162770	TF1	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10358060
67585909	67585932	15	+	28162770	TF1	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	NaN	[NaN]	[470]	1	hSpCas9	negative selection	10358061
67630886	67630909	15	+	28162770	TF1	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	NaN	[NaN]	[499]	1	hSpCas9	negative selection	10358062
67703333	67703356	15	+	28162770	SKM1	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	-2.5064998722940763	[44]	[13]	-9	hSpCas9	negative selection	10527419
67692498	67692521	15	+	28162770	SKM1	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-2.1439297929093675	[19]	[7]	-8	hSpCas9	negative selection	10527420
67563314	67563337	15	+	28162770	SKM1	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	-0.9740047914670555	[99]	[89]	-6	hSpCas9	negative selection	10527421
67580761	67580784	15	-	28162770	SKM1	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.15457703710887627	[118]	[188]	-1	hSpCas9	negative selection	10527422
67580802	67580825	15	+	28162770	SKM1	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.1072953106347927	[114]	[218]	1	hSpCas9	negative selection	10527423
67600712	67600735	15	+	28162770	SKM1	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	-1.3844216300920733	[126]	[85]	-7	hSpCas9	negative selection	10527424
67769602	67769625	15	+	28162770	SKM1	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	-1.4349785749127584	[129]	[84]	-7	hSpCas9	negative selection	10527425
67769609	67769632	15	-	28162770	SKM1	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	-1.0443941193584534	[20]	[17]	-6	hSpCas9	negative selection	10527426
67585909	67585932	15	+	28162770	SKM1	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	-0.7955294866608145	[107]	[109]	-5	hSpCas9	negative selection	10527427
67630886	67630909	15	+	28162770	SKM1	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	-0.03441003078583127	[83]	[144]	0	hSpCas9	negative selection	10527428
67703333	67703356	15	+	28162770	SKM1	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	-2.5064998722940763	[44]	[13]	-9	hSpCas9	negative selection	10696785
67692498	67692521	15	+	28162770	SKM1	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-2.1439297929093675	[19]	[7]	-8	hSpCas9	negative selection	10696786
67563314	67563337	15	+	28162770	SKM1	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	-0.9740047914670555	[99]	[89]	-6	hSpCas9	negative selection	10696787
67580761	67580784	15	-	28162770	SKM1	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.15457703710887627	[118]	[188]	-1	hSpCas9	negative selection	10696788
67580802	67580825	15	+	28162770	SKM1	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.1072953106347927	[114]	[218]	1	hSpCas9	negative selection	10696789
67600712	67600735	15	+	28162770	SKM1	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	-1.3844216300920733	[126]	[85]	-7	hSpCas9	negative selection	10696790
67769602	67769625	15	+	28162770	SKM1	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	-1.4349785749127584	[129]	[84]	-7	hSpCas9	negative selection	10696791
67769609	67769632	15	-	28162770	SKM1	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	-1.0443941193584534	[20]	[17]	-6	hSpCas9	negative selection	10696792
67585909	67585932	15	+	28162770	SKM1	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	-0.7955294866608145	[107]	[109]	-5	hSpCas9	negative selection	10696793
67630886	67630909	15	+	28162770	SKM1	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	-0.03441003078583127	[83]	[144]	0	hSpCas9	negative selection	10696794
67703333	67703356	15	+	28162770	PL21	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	0.8751774595123245	[118]	[94]	7	hSpCas9	negative selection	10866151
67692498	67692521	15	+	28162770	PL21	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.6717606421345315	[74]	[51]	6	hSpCas9	negative selection	10866152
67563314	67563337	15	+	28162770	PL21	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.03647360351869011	[344]	[153]	0	hSpCas9	negative selection	10866153
67580761	67580784	15	-	28162770	PL21	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	1.1658992900708876	[468]	[457]	8	hSpCas9	negative selection	10866154
67580802	67580825	15	+	28162770	PL21	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.18256698504137026	[412]	[203]	1	hSpCas9	negative selection	10866155
67600712	67600735	15	+	28162770	PL21	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	0.23882008265337995	[367]	[188]	2	hSpCas9	negative selection	10866156
67769602	67769625	15	+	28162770	PL21	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	0.16554095296535332	[421]	[205]	1	hSpCas9	negative selection	10866157
67769609	67769632	15	-	28162770	PL21	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	0.017275557339509584	[83]	[36]	0	hSpCas9	negative selection	10866158
67585909	67585932	15	+	28162770	PL21	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	0.4425377276288156	[398]	[235]	4	hSpCas9	negative selection	10866159
67630886	67630909	15	+	28162770	PL21	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.5405383128754084	[356]	[225]	5	hSpCas9	negative selection	10866160
67703333	67703356	15	+	28162770	P31FUJ	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	0.1760033411529507	[173]	[230]	1	hSpCas9	negative selection	11035517
67692498	67692521	15	+	28162770	P31FUJ	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.8062976152745616	[90]	[186]	8	hSpCas9	negative selection	11035518
67563314	67563337	15	+	28162770	P31FUJ	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.1453592926294326	[316]	[411]	1	hSpCas9	negative selection	11035519
67580761	67580784	15	-	28162770	P31FUJ	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.16044508951541858	[516]	[678]	1	hSpCas9	negative selection	11035520
67580802	67580825	15	+	28162770	P31FUJ	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.3104235640339551	[338]	[493]	3	hSpCas9	negative selection	11035521
67600712	67600735	15	+	28162770	P31FUJ	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	-0.21333234021615377	[367]	[372]	-2	hSpCas9	negative selection	11035522
67769602	67769625	15	+	28162770	P31FUJ	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	-0.0014766583079228734	[505]	[593]	0	hSpCas9	negative selection	11035523
67769609	67769632	15	-	28162770	P31FUJ	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	0.307766176948324	[76]	[111]	3	hSpCas9	negative selection	11035524
67585909	67585932	15	+	28162770	P31FUJ	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	0.38963500172544063	[455]	[701]	4	hSpCas9	negative selection	11035525
67630886	67630909	15	+	28162770	P31FUJ	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.3786325076679684	[467]	[714]	4	hSpCas9	negative selection	11035526
67703333	67703356	15	+	28162770	OCIAML5	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	0.3427496061200261	[82]	[189]	3	hSpCas9	negative selection	11204883
67692498	67692521	15	+	28162770	OCIAML5	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-0.12907391925039513	[82]	[136]	-1	hSpCas9	negative selection	11204884
67563314	67563337	15	+	28162770	OCIAML5	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	-0.39901574564842185	[205]	[281]	-3	hSpCas9	negative selection	11204885
67580761	67580784	15	-	28162770	OCIAML5	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.5008654264726213	[266]	[681]	4	hSpCas9	negative selection	11204886
67580802	67580825	15	+	28162770	OCIAML5	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.860176593890978	[205]	[674]	7	hSpCas9	negative selection	11204887
67600712	67600735	15	+	28162770	OCIAML5	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	0.11221150690204129	[183]	[358]	0	hSpCas9	negative selection	11204888
67769602	67769625	15	+	28162770	OCIAML5	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	0.08855488205707118	[309]	[594]	0	hSpCas9	negative selection	11204889
67769609	67769632	15	-	28162770	OCIAML5	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	1.0114314292311408	[71]	[261]	8	hSpCas9	negative selection	11204890
67585909	67585932	15	+	28162770	OCIAML5	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	0.3934094635854921	[247]	[587]	3	hSpCas9	negative selection	11204891
67630886	67630909	15	+	28162770	OCIAML5	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.567287608397965	[291]	[780]	5	hSpCas9	negative selection	11204892
67703333	67703356	15	+	28162770	EOL1	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	0.390034293536736	[280]	[193]	3	hSpCas9	negative selection	11374249
67692498	67692521	15	+	28162770	EOL1	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.7801578622353598	[83]	[75]	7	hSpCas9	negative selection	11374250
67563314	67563337	15	+	28162770	EOL1	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.40489520741223783	[690]	[481]	3	hSpCas9	negative selection	11374251
67580761	67580784	15	-	28162770	EOL1	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.5258490091064385	[877]	[665]	5	hSpCas9	negative selection	11374252
67580802	67580825	15	+	28162770	EOL1	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	1.1429046796718256	[715]	[832]	8	hSpCas9	negative selection	11374253
67600712	67600735	15	+	28162770	EOL1	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	0.6430239941698761	[800]	[658]	6	hSpCas9	negative selection	11374254
67769602	67769625	15	+	28162770	EOL1	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	-0.08884782179850825	[540]	[267]	0	hSpCas9	negative selection	11374255
67769609	67769632	15	-	28162770	EOL1	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	1.6794352737340033	[47]	[80]	9	hSpCas9	negative selection	11374256
67585909	67585932	15	+	28162770	EOL1	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	-0.03182529602920747	[455]	[234]	0	hSpCas9	negative selection	11374257
67630886	67630909	15	+	28162770	EOL1	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.7837616638312983	[483]	[438]	7	hSpCas9	negative selection	11374258
67703333	67703356	15	+	28162770	MOLM13	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	2.0544225901409616	[305]	[918]	9	hSpCas9	negative selection	11543615
67692498	67692521	15	+	28162770	MOLM13	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-0.06148079321325972	[139]	[96]	0	hSpCas9	negative selection	11543616
67563314	67563337	15	+	28162770	MOLM13	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	1.0229378284818595	[600]	[882]	7	hSpCas9	negative selection	11543617
67580761	67580784	15	-	28162770	MOLM13	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	1.0628359708383572	[671]	[1014]	7	hSpCas9	negative selection	11543618
67580802	67580825	15	+	28162770	MOLM13	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	1.119729745084037	[554]	[871]	8	hSpCas9	negative selection	11543619
67600712	67600735	15	+	28162770	MOLM13	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	1.096733771886555	[625]	[967]	8	hSpCas9	negative selection	11543620
67769602	67769625	15	+	28162770	MOLM13	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	0.11775640539809329	[593]	[465]	0	hSpCas9	negative selection	11543621
67769609	67769632	15	-	28162770	MOLM13	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	0.1575492609324285	[92]	[74]	1	hSpCas9	negative selection	11543622
67585909	67585932	15	+	28162770	MOLM13	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	-0.22517572648595297	[560]	[346]	-1	hSpCas9	negative selection	11543623
67630886	67630909	15	+	28162770	MOLM13	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.8338270264794959	[522]	[673]	6	hSpCas9	negative selection	11543624
67703333	67703356	15	+	28162770	HEL	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	0.210153131510666	[192]	[142]	1	hSpCas9	negative selection	11712981
67692498	67692521	15	+	28162770	HEL	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.06623791002739687	[84]	[56]	0	hSpCas9	negative selection	11712982
67563314	67563337	15	+	28162770	HEL	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.5611734798442795	[472]	[446]	5	hSpCas9	negative selection	11712983
67580761	67580784	15	-	28162770	HEL	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.4635895965421839	[607]	[536]	4	hSpCas9	negative selection	11712984
67580802	67580825	15	+	28162770	HEL	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.645458333353949	[529]	[530]	5	hSpCas9	negative selection	11712985
67600712	67600735	15	+	28162770	HEL	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	0.3835464924609573	[449]	[375]	3	hSpCas9	negative selection	11712986
67769602	67769625	15	+	28162770	HEL	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	-0.31080185690698303	[549]	[283]	-2	hSpCas9	negative selection	11712987
67769609	67769632	15	-	28162770	HEL	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	-0.1646160900572473	[90]	[51]	-1	hSpCas9	negative selection	11712988
67585909	67585932	15	+	28162770	HEL	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	-0.5816927346096896	[471]	[201]	-4	hSpCas9	negative selection	11712989
67630886	67630909	15	+	28162770	HEL	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.5442489686009936	[393]	[367]	4	hSpCas9	negative selection	11712990
67703333	67703356	15	+	28162770	MV411	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	0.8089410786799426	[123]	[182]	7	hSpCas9	negative selection	11882347
67692498	67692521	15	+	28162770	MV411	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-1.415527461939654	[75]	[23]	-7	hSpCas9	negative selection	11882348
67563314	67563337	15	+	28162770	MV411	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.7483357867154572	[317]	[449]	6	hSpCas9	negative selection	11882349
67580761	67580784	15	-	28162770	MV411	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.20479321337428136	[411]	[399]	1	hSpCas9	negative selection	11882350
67580802	67580825	15	+	28162770	MV411	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.7695123455485411	[421]	[605]	7	hSpCas9	negative selection	11882351
67600712	67600735	15	+	28162770	MV411	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	0.5443290947328134	[371]	[456]	5	hSpCas9	negative selection	11882352
67769602	67769625	15	+	28162770	MV411	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	0.8739296249131788	[330]	[510]	7	hSpCas9	negative selection	11882353
67769609	67769632	15	-	28162770	MV411	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	0.5535406785084551	[54]	[67]	5	hSpCas9	negative selection	11882354
67585909	67585932	15	+	28162770	MV411	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	0.36629236801081255	[360]	[391]	3	hSpCas9	negative selection	11882355
67630886	67630909	15	+	28162770	MV411	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	1.1065750149429256	[300]	[545]	8	hSpCas9	negative selection	11882356
67703333	67703356	15	+	28162770	MONOMAC1	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	0.8677334083306842	[97]	[204]	7	hSpCas9	negative selection	12051713
67692498	67692521	15	+	28162770	MONOMAC1	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.5563231853573212	[34]	[58]	5	hSpCas9	negative selection	12051714
67563314	67563337	15	+	28162770	MONOMAC1	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.21354100402859033	[242]	[322]	2	hSpCas9	negative selection	12051715
67580761	67580784	15	-	28162770	MONOMAC1	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.13454141786152785	[297]	[374]	1	hSpCas9	negative selection	12051716
67580802	67580825	15	+	28162770	MONOMAC1	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.17100317268212095	[233]	[301]	1	hSpCas9	negative selection	12051717
67600712	67600735	15	+	28162770	MONOMAC1	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	0.9833500932013831	[228]	[518]	8	hSpCas9	negative selection	12051718
67769602	67769625	15	+	28162770	MONOMAC1	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	1.1140642173434534	[213]	[530]	8	hSpCas9	negative selection	12051719
67769609	67769632	15	-	28162770	MONOMAC1	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	-0.7819993477807097	[44]	[29]	-6	hSpCas9	negative selection	12051720
67585909	67585932	15	+	28162770	MONOMAC1	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	0.5438759316233153	[218]	[365]	5	hSpCas9	negative selection	12051721
67630886	67630909	15	+	28162770	MONOMAC1	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	1.2250097107386533	[230]	[618]	9	hSpCas9	negative selection	12051722
67703333	67703356	15	+	28162770	OCIAML2	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	0.07853195405114809	[33]	[198]	0	hSpCas9	negative selection	12221079
67692498	67692521	15	+	28162770	OCIAML2	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	0.27083716115898593	[15]	[106]	2	hSpCas9	negative selection	12221080
67563314	67563337	15	+	28162770	OCIAML2	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.39673240617971994	[73]	[539]	4	hSpCas9	negative selection	12221081
67580761	67580784	15	-	28162770	OCIAML2	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	0.37996219065603953	[107]	[778]	3	hSpCas9	negative selection	12221082
67580802	67580825	15	+	28162770	OCIAML2	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.9430612483291659	[66]	[713]	8	hSpCas9	negative selection	12221083
67600712	67600735	15	+	28162770	OCIAML2	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	0.294453444027196	[93]	[638]	3	hSpCas9	negative selection	12221084
67769602	67769625	15	+	28162770	OCIAML2	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	0.8680322854050023	[59]	[606]	8	hSpCas9	negative selection	12221085
67769609	67769632	15	-	28162770	OCIAML2	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	0.7281500388723364	[10]	[100]	7	hSpCas9	negative selection	12221086
67585909	67585932	15	+	28162770	OCIAML2	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	-0.045447768557774326	[61]	[332]	0	hSpCas9	negative selection	12221087
67630886	67630909	15	+	28162770	OCIAML2	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.4964782932004641	[60]	[476]	5	hSpCas9	negative selection	12221088
67703333	67703356	15	+	28162770	OCIAML3	viability	GCAGCCTGAAAGGATTTCAGGGG	MAP2K5	ENSG00000137764	-0.17478234408188592	[42]	[114]	-1	hSpCas9	negative selection	12390445
67692498	67692521	15	+	28162770	OCIAML3	viability	GCTAGTAAACACAAGAGGACAGG	MAP2K5	ENSG00000137764	-1.5268934444656261	[20]	[21]	-8	hSpCas9	negative selection	12390446
67563314	67563337	15	+	28162770	OCIAML3	viability	GAGAAGTGATGAGGAAATGAAGG	MAP2K5	ENSG00000137764	0.1585548088930615	[91]	[309]	1	hSpCas9	negative selection	12390447
67580761	67580784	15	-	28162770	OCIAML3	viability	TACTTGCTGTTCCATTACTGTGG	MAP2K5	ENSG00000137764	-0.21926284699335263	[117]	[305]	-2	hSpCas9	negative selection	12390448
67580802	67580825	15	+	28162770	OCIAML3	viability	CCTCTGCAGATATTTCCAAGAGG	MAP2K5	ENSG00000137764	0.11480094135408492	[118]	[388]	1	hSpCas9	negative selection	12390449
67600712	67600735	15	+	28162770	OCIAML3	viability	GACACTCTTGGTCATGGCAACGG	MAP2K5	ENSG00000137764	-0.9140967355477444	[97]	[156]	-6	hSpCas9	negative selection	12390450
67769602	67769625	15	+	28162770	OCIAML3	viability	GATTCGCCCGTCCTTCCAGTTGG	MAP2K5	ENSG00000137764	-0.5311667667539317	[145]	[304]	-4	hSpCas9	negative selection	12390451
67769609	67769632	15	-	28162770	OCIAML3	viability	GAACTCTCCAACTGGAAGGACGG	MAP2K5	ENSG00000137764	-1.7708854024082425	[25]	[22]	-8	hSpCas9	negative selection	12390452
67585909	67585932	15	+	28162770	OCIAML3	viability	ACGGAACATACATGGCCTGAAGG	MAP2K5	ENSG00000137764	1.2634142790200553	[88]	[644]	9	hSpCas9	negative selection	12390453
67630886	67630909	15	+	28162770	OCIAML3	viability	AGAGCATATCATGTCCCGAGTGG	MAP2K5	ENSG00000137764	0.2034994957770937	[125]	[437]	2	hSpCas9	negative selection	12390454