Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4214
• Symbol:MAP3K1
• Description:mitogen-activated protein kinase kinase kinase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/MAP3K1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
56815823	56815846	5	-	26472758	Jiyoye	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-3.1371451347179367	[69]	[5]	-9	hSpCas9	negative selection	95946
56864755	56864778	5	-	26472758	Jiyoye	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-1.199482190314602	[66]	[21]	-7	hSpCas9	negative selection	95947
56882106	56882129	5	-	26472758	Jiyoye	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	-1.1240992483212946	[210]	[72]	-6	hSpCas9	negative selection	95948
56882803	56882826	5	-	26472758	Jiyoye	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	0.12219842279140258	[211]	[173]	0	hSpCas9	negative selection	95949
56815561	56815584	5	+	26472758	Jiyoye	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	-0.874967847275625	[303]	[124]	-6	hSpCas9	negative selection	95950
56815599	56815622	5	-	26472758	Jiyoye	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	0.7083449162264382	[55]	[68]	5	hSpCas9	negative selection	95951
56815879	56815902	5	+	26472758	Jiyoye	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-0.805485501812801	[196]	[84]	-5	hSpCas9	negative selection	95952
56815823	56815846	5	-	26472758	KBM7	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-1.2245504377319136	[90,49]	[16,10]	-7	hSpCas9	negative selection	287064
56864755	56864778	5	-	26472758	KBM7	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-0.692741412413536	[59,95]	[16,28]	-5	hSpCas9	negative selection	287065
56882106	56882129	5	-	26472758	KBM7	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.1919670988837292	[453,377]	[251,195]	2	hSpCas9	negative selection	287066
56882803	56882826	5	-	26472758	KBM7	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	0.08442898811710553	[756,543]	[264,369]	0	hSpCas9	negative selection	287067
56815561	56815584	5	+	26472758	KBM7	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	0.1261698481935613	[637,213]	[169,242]	1	hSpCas9	negative selection	287068
56815599	56815622	5	-	26472758	KBM7	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	-0.1280434452398831	[149,59]	[44,41]	-1	hSpCas9	negative selection	287069
56815879	56815902	5	+	26472758	KBM7	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-2.003586188506409	[470,364]	[36,58]	-8	hSpCas9	negative selection	287070
56815823	56815846	5	-	26472758	Raji	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-0.3374013072992965	[48]	[8]	-3	hSpCas9	negative selection	478182
56864755	56864778	5	-	26472758	Raji	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-0.8786772736685267	[102]	[12]	-6	hSpCas9	negative selection	478183
56882106	56882129	5	-	26472758	Raji	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	-0.15453725014948583	[258]	[53]	-1	hSpCas9	negative selection	478184
56882803	56882826	5	-	26472758	Raji	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	-0.11500888596284833	[293]	[62]	-1	hSpCas9	negative selection	478185
56815561	56815584	5	+	26472758	Raji	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	-0.36312024076264177	[326]	[58]	-3	hSpCas9	negative selection	478186
56815599	56815622	5	-	26472758	Raji	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	1.3704179412073934	[44]	[26]	9	hSpCas9	negative selection	478187
56815879	56815902	5	+	26472758	Raji	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-1.4045155031578331	[307]	[26]	-7	hSpCas9	negative selection	478188
56815823	56815846	5	-	26472758	K562	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-1.6180777485836182	[39]	[10]	-7	hSpCas9	negative selection	669300
56864755	56864778	5	-	26472758	K562	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-4.725207623290034	[93]	[2]	-9	hSpCas9	negative selection	669301
56882106	56882129	5	-	26472758	K562	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.6236716518053169	[448]	[583]	5	hSpCas9	negative selection	669302
56882803	56882826	5	-	26472758	K562	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	-0.03991507996780322	[463]	[380]	0	hSpCas9	negative selection	669303
56815561	56815584	5	+	26472758	K562	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	-0.19358633315952367	[400]	[295]	-1	hSpCas9	negative selection	669304
56815599	56815622	5	-	26472758	K562	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	1.3033124167200156	[59]	[124]	9	hSpCas9	negative selection	669305
56815879	56815902	5	+	26472758	K562	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-1.1925335480408377	[397]	[146]	-6	hSpCas9	negative selection	669306
56815628	56815651	5	+	26627737	DLD1	viability	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	1.1625841289864793	[136]	[104,125,62]	9	hSpCas9	negative selection	829087
56864817	56864840	5	-	26627737	DLD1	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.058495690365261144	[2809]	[778,1268,738]	0	hSpCas9	negative selection	829088
56865883	56865906	5	-	26627737	DLD1	viability	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-0.036039637547304826	[594]	[182,271,104]	0	hSpCas9	negative selection	829089
56872896	56872919	5	+	26627737	DLD1	viability	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.5124337548478524	[451]	[116,60,114]	-5	hSpCas9	negative selection	829090
56815628	56815651	5	+	26627737	GBM cells	viability after 5 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	0.9168357828829479	[39]	[25,54]	9	hSpCas9	negative selection	911402
56864817	56864840	5	-	26627737	GBM cells	viability after 5 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.25858937608121435	[1274]	[910,724]	4	hSpCas9	negative selection	911403
56865883	56865906	5	-	26627737	GBM cells	viability after 5 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-0.03260638723154782	[287]	[153,147]	0	hSpCas9	negative selection	911404
56872896	56872919	5	+	26627737	GBM cells	viability after 5 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	0.5436485961242108	[196]	[126,180]	7	hSpCas9	negative selection	911405
56815628	56815651	5	+	26627737	GBM cells	viability after 13 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	0.7584033787708384	[39]	[12,55]	8	hSpCas9	negative selection	993717
56864817	56864840	5	-	26627737	GBM cells	viability after 13 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.09830644109155173	[1274]	[921,592]	1	hSpCas9	negative selection	993718
56865883	56865906	5	-	26627737	GBM cells	viability after 13 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-0.13196195050825005	[287]	[178,112]	-2	hSpCas9	negative selection	993719
56872896	56872919	5	+	26627737	GBM cells	viability after 13 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	0.2689741973243828	[196]	[130,126]	3	hSpCas9	negative selection	993720
56815628	56815651	5	+	26627737	GBM cells	viability after 21 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	1.9164435515779372	[39]	[92,71]	9	hSpCas9	negative selection	1076032
56864817	56864840	5	-	26627737	GBM cells	viability after 21 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.17636980047665674	[1274]	[811,755]	1	hSpCas9	negative selection	1076033
56865883	56865906	5	-	26627737	GBM cells	viability after 21 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-0.0626908832456935	[287]	[165,134]	0	hSpCas9	negative selection	1076034
56872896	56872919	5	+	26627737	GBM cells	viability after 21 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	1.1169223156457935	[196]	[240,223]	9	hSpCas9	negative selection	1076035
56815628	56815651	5	+	26627737	RPE1	viability after 9 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.5687557912917044	[428]	[52,138]	-4	hSpCas9	negative selection	1158347
56864817	56864840	5	-	26627737	RPE1	viability after 9 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.03826829189313408	[4753]	[1230,1911]	0	hSpCas9	negative selection	1158348
56865883	56865906	5	-	26627737	RPE1	viability after 9 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	1.0197256924762377	[854]	[371,762]	6	hSpCas9	negative selection	1158349
56872896	56872919	5	+	26627737	RPE1	viability after 9 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	0.9549389999724682	[337]	[174,243]	6	hSpCas9	negative selection	1158350
56815628	56815651	5	+	26627737	RPE1	viability after 12 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.3860156751562497	[428]	[94,80]	-3	hSpCas9	negative selection	1240662
56864817	56864840	5	-	26627737	RPE1	viability after 12 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.4744169258690403	[4753]	[1792,1754]	3	hSpCas9	negative selection	1240663
56865883	56865906	5	-	26627737	RPE1	viability after 12 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	0.4431855535331981	[854]	[339,282]	3	hSpCas9	negative selection	1240664
56872896	56872919	5	+	26627737	RPE1	viability after 12 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	1.4338874348820505	[337]	[222,268]	7	hSpCas9	negative selection	1240665
56815628	56815651	5	+	26627737	RPE1	viability after 15 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.9914917446657573	[428]	[58,62]	-6	hSpCas9	negative selection	1322977
56864817	56864840	5	-	26627737	RPE1	viability after 15 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.6824334185667578	[4753]	[2343,1978]	4	hSpCas9	negative selection	1322978
56865883	56865906	5	-	26627737	RPE1	viability after 15 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	0.49183912274529895	[854]	[389,291]	3	hSpCas9	negative selection	1322979
56872896	56872919	5	+	26627737	RPE1	viability after 15 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	1.2817738279240485	[337]	[205,257]	7	hSpCas9	negative selection	1322980
56815628	56815651	5	+	26627737	RPE1	viability after 18 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.7379471845937818	[428]	[66,71]	-4	hSpCas9	negative selection	1405292
56864817	56864840	5	-	26627737	RPE1	viability after 18 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.3032178469254747	[4753]	[1379,1799]	2	hSpCas9	negative selection	1405293
56865883	56865906	5	-	26627737	RPE1	viability after 18 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	0.34415436770382424	[854]	[391,186]	2	hSpCas9	negative selection	1405294
56872896	56872919	5	+	26627737	RPE1	viability after 18 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	1.1165215069792431	[337]	[132,266]	6	hSpCas9	negative selection	1405295
56815628	56815651	5	+	26627737	HeLa	viability after 8 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-1.0804117567846476	[184]	[23,2,80]	-8	hSpCas9	negative selection	1487607
56864817	56864840	5	-	26627737	HeLa	viability after 8 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.7534636170566473	[1368]	[1239,1062,777]	6	hSpCas9	negative selection	1487608
56865883	56865906	5	-	26627737	HeLa	viability after 8 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	0.28222113200060805	[261]	[286,58,104]	2	hSpCas9	negative selection	1487609
56872896	56872919	5	+	26627737	HeLa	viability after 8 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.28647167370693666	[396]	[283,26,144]	-3	hSpCas9	negative selection	1487610
56815628	56815651	5	+	26627737	HeLa	viability after 12 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.6662460329618847	[184]	[0,77,60]	-5	hSpCas9	negative selection	1569922
56864817	56864840	5	-	26627737	HeLa	viability after 12 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.44151115458978896	[1368]	[1068,755,489]	4	hSpCas9	negative selection	1569923
56865883	56865906	5	-	26627737	HeLa	viability after 12 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	0.6579339567661424	[261]	[274,175,63]	5	hSpCas9	negative selection	1569924
56872896	56872919	5	+	26627737	HeLa	viability after 12 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.25731679768559257	[396]	[359,35,32]	-2	hSpCas9	negative selection	1569925
56815628	56815651	5	+	26627737	HeLa	viability after 15 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.23016544973910258	[184]	[21,108,61]	-2	hSpCas9	negative selection	1652237
56864817	56864840	5	-	26627737	HeLa	viability after 15 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.5537066103099593	[1368]	[806,1062,564]	4	hSpCas9	negative selection	1652238
56865883	56865906	5	-	26627737	HeLa	viability after 15 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-0.054448198182433405	[261]	[79,154,70]	0	hSpCas9	negative selection	1652239
56872896	56872919	5	+	26627737	HeLa	viability after 15 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.6760839988985068	[396]	[135,77,87]	-5	hSpCas9	negative selection	1652240
56815628	56815651	5	+	26627737	HeLa	viability after 18 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.21140289174946258	[184]	[14,91,61]	-2	hSpCas9	negative selection	1734552
56864817	56864840	5	-	26627737	HeLa	viability after 18 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.5491446430609821	[1368]	[530,886,564]	4	hSpCas9	negative selection	1734553
56865883	56865906	5	-	26627737	HeLa	viability after 18 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-0.05844397069950491	[261]	[50,130,70]	0	hSpCas9	negative selection	1734554
56872896	56872919	5	+	26627737	HeLa	viability after 18 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.6336039285192978	[396]	[95,65,87]	-5	hSpCas9	negative selection	1734555
56815628	56815651	5	+	26627737	HCT116	viability after 6 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	1.7603937100913742	[115]	[171,0]	8	hSpCas9	negative selection	1816867
56864817	56864840	5	-	26627737	HCT116	viability after 6 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.28869174844339884	[2118]	[763,209]	1	hSpCas9	negative selection	1816868
56865883	56865906	5	-	26627737	HCT116	viability after 6 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-1.8142800625888877	[756]	[67,14]	-8	hSpCas9	negative selection	1816869
56872896	56872919	5	+	26627737	HCT116	viability after 6 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-3.2480665666565782	[575]	[24,0]	-9	hSpCas9	negative selection	1816870
56815628	56815651	5	+	26627737	HCT116	viability after 8 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-1.3966346720798202	[192]	[23,65,30]	-9	hSpCas9	negative selection	1899182
56864817	56864840	5	-	26627737	HCT116	viability after 8 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.07768540816140224	[1244]	[676,843,650]	0	hSpCas9	negative selection	1899183
56865883	56865906	5	-	26627737	HCT116	viability after 8 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-0.8009675230199391	[626]	[240,183,170]	-7	hSpCas9	negative selection	1899184
56872896	56872919	5	+	26627737	HCT116	viability after 8 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.5501900034692955	[253]	[147,69,69]	-6	hSpCas9	negative selection	1899185
56815628	56815651	5	+	26627737	HCT116	viability after 9 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	0.09965029596712593	[115]	[59,11]	0	hSpCas9	negative selection	1981497
56864817	56864840	5	-	26627737	HCT116	viability after 9 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.4496252134962182	[2118]	[989,600]	3	hSpCas9	negative selection	1981498
56865883	56865906	5	-	26627737	HCT116	viability after 9 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-1.0510963727674052	[756]	[139,63]	-6	hSpCas9	negative selection	1981499
56872896	56872919	5	+	26627737	HCT116	viability after 9 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.12879850210281496	[575]	[181,107]	-1	hSpCas9	negative selection	1981500
56815628	56815651	5	+	26627737	HCT116	viability after 12 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.673801609908824	[192]	[70,59,58]	-6	hSpCas9	negative selection	2063812
56864817	56864840	5	-	26627737	HCT116	viability after 12 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.2672601627691851	[1244]	[695,937,739]	2	hSpCas9	negative selection	2063813
56865883	56865906	5	-	26627737	HCT116	viability after 12 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-1.304312025863526	[626]	[142,115,139]	-8	hSpCas9	negative selection	2063814
56872896	56872919	5	+	26627737	HCT116	viability after 12 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	0.10959783567086587	[253]	[112,152,168]	1	hSpCas9	negative selection	2063815
56815628	56815651	5	+	26627737	HCT116	viability after 15 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-1.0689198044083588	[192]	[38,79,37]	-8	hSpCas9	negative selection	2146127
56864817	56864840	5	-	26627737	HCT116	viability after 15 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.01926232245268178	[1244]	[862,796,532]	0	hSpCas9	negative selection	2146128
56865883	56865906	5	-	26627737	HCT116	viability after 15 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-1.3478471687679356	[626]	[190,144,94]	-8	hSpCas9	negative selection	2146129
56872896	56872919	5	+	26627737	HCT116	viability after 15 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.09402546735156259	[253]	[188,59,166]	-1	hSpCas9	negative selection	2146130
56815628	56815651	5	+	26627737	HCT116	viability after 18 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.8262144340687092	[192]	[32,110,7]	-6	hSpCas9	negative selection	2228442
56864817	56864840	5	-	26627737	HCT116	viability after 18 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.009970488762483853	[1244]	[652,562,604]	0	hSpCas9	negative selection	2228443
56865883	56865906	5	-	26627737	HCT116	viability after 18 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-0.8746667316295101	[626]	[164,87,251]	-7	hSpCas9	negative selection	2228444
56872896	56872919	5	+	26627737	HCT116	viability after 18 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.28120275114907306	[253]	[119,85,97]	-3	hSpCas9	negative selection	2228445
56815589	56815612	5	+	24336569	HL60	viability	GGGAATCGCGCCTCGTCGTCGGG	MAP3K1	ENSG00000095015	-0.3949846999170591	[662]	[1066]	-4	hSpCas9	negative selection	2275818
56815597	56815620	5	+	24336569	HL60	viability	CGCCTCGTCGTCGGGATTCCCGG	MAP3K1	ENSG00000095015	0.8324268842521818	[232]	[877]	6	hSpCas9	negative selection	2275819
56815605	56815628	5	+	24336569	HL60	viability	CGTCGGGATTCCCGGGCGCCAGG	MAP3K1	ENSG00000095015	1.777605857972863	[136]	[993]	9	hSpCas9	negative selection	2275820
56815615	56815638	5	-	24336569	HL60	viability	GGCTCGTAGCCCTGGCGCCCGGG	MAP3K1	ENSG00000095015	0.8436819046868902	[355]	[1351]	7	hSpCas9	negative selection	2275821
56815621	56815644	5	+	24336569	HL60	viability	CGCCAGGGCTACGAGCCCTGAGG	MAP3K1	ENSG00000095015	-2.7066904715637796	[326]	[105]	-9	hSpCas9	negative selection	2275822
56815628	56815651	5	+	24336569	HL60	viability	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	0.9031995889886987	[661]	[2619]	7	hSpCas9	negative selection	2275823
56815634	56815657	5	+	24336569	HL60	viability	AGCCCTGAGGCAGGCGGCGGCGG	MAP3K1	ENSG00000095015	0.723541537338679	[877]	[3067]	6	hSpCas9	negative selection	2275824
56815648	56815671	5	+	24336569	HL60	viability	CGGCGGCGGAGGAGCCCTCAAGG	MAP3K1	ENSG00000095015	0.7683955499432434	[472]	[1704]	6	hSpCas9	negative selection	2275825
56815662	56815685	5	-	24336569	HL60	viability	GGGCGCGCTGCTCGCCTTGAGGG	MAP3K1	ENSG00000095015	0.3242519885721207	[1280]	[3393]	3	hSpCas9	negative selection	2275826
56815682	56815705	5	-	24336569	HL60	viability	AGCAGTCCCGCGGCAGCCGCGGG	MAP3K1	ENSG00000095015	0.6387582297027334	[389]	[1284]	5	hSpCas9	negative selection	2275827
56815589	56815612	5	+	24336569	KBM7	viability	GGGAATCGCGCCTCGTCGTCGGG	MAP3K1	ENSG00000095015	0.2853468963872673	[607]	[2020]	2	hSpCas9	negative selection	2342995
56815597	56815620	5	+	24336569	KBM7	viability	CGCCTCGTCGTCGGGATTCCCGG	MAP3K1	ENSG00000095015	1.4593113990596358	[67]	[509]	9	hSpCas9	negative selection	2342996
56815605	56815628	5	+	24336569	KBM7	viability	CGTCGGGATTCCCGGGCGCCAGG	MAP3K1	ENSG00000095015	1.4391737534885598	[100]	[746]	9	hSpCas9	negative selection	2342997
56815615	56815638	5	-	24336569	KBM7	viability	GGCTCGTAGCCCTGGCGCCCGGG	MAP3K1	ENSG00000095015	-0.7679262556167645	[569]	[912]	-5	hSpCas9	negative selection	2342998
56815621	56815644	5	+	24336569	KBM7	viability	CGCCAGGGCTACGAGCCCTGAGG	MAP3K1	ENSG00000095015	1.941848789972844	[118]	[1246]	9	hSpCas9	negative selection	2342999
56815628	56815651	5	+	24336569	KBM7	viability	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	0.1513117290304491	[858]	[2601]	1	hSpCas9	negative selection	2343000
56815634	56815657	5	+	24336569	KBM7	viability	AGCCCTGAGGCAGGCGGCGGCGG	MAP3K1	ENSG00000095015	-0.2754295299920564	[863]	[1946]	-2	hSpCas9	negative selection	2343001
56815648	56815671	5	+	24336569	KBM7	viability	CGGCGGCGGAGGAGCCCTCAAGG	MAP3K1	ENSG00000095015	-0.30609032484776877	[722]	[1594]	-3	hSpCas9	negative selection	2343002
56815662	56815685	5	-	24336569	KBM7	viability	GGGCGCGCTGCTCGCCTTGAGGG	MAP3K1	ENSG00000095015	1.140169327003111	[775]	[4664]	8	hSpCas9	negative selection	2343003
56815682	56815705	5	-	24336569	KBM7	viability	AGCAGTCCCGCGGCAGCCGCGGG	MAP3K1	ENSG00000095015	-0.6250378706766025	[431]	[763]	-5	hSpCas9	negative selection	2343004
56866373	56866396	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGGTCTTGTTCTGTCACCTAG	MAP3K1	ENSG00000095015	1.8873495753995055	[277,92]	[61,243]	6	dCas9-VP64	positive selection	2402491
56829463	56829486	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGTGAGCCACCATGCCGAG	MAP3K1	ENSG00000095015	-2.540049325425791	[4,100]	[0,1]	-9	dCas9-VP64	positive selection	2419162
56827670	56827693	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCATGTTGGCCTGG	MAP3K1	ENSG00000095015	2.4187836580270234	[16,66]	[4,98]	7	dCas9-VP64	positive selection	2461497
56866373	56866396	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGGTCTTGTTCTGTCACCTAG	MAP3K1	ENSG00000095015	-0.6627118139888153	[169,193]	[38,34]	-6	dCas9-VP64	positive selection	2497746
56829463	56829486	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGTGAGCCACCATGCCGAG	MAP3K1	ENSG00000095015	0.03661325214909955	[138,24]	[31,22]	0	dCas9-VP64	positive selection	2514417
56827670	56827693	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCATGTTGGCCTGG	MAP3K1	ENSG00000095015	0.6489514996892785	[92,108]	[43,57]	5	dCas9-VP64	positive selection	2556752
56815756	56815779	5	+	27013184	SW480	treatment with recombinant TRAIL	GCTGCGCAAAGTGCGGAGTGTGG	MAP3K1	ENSG00000095015	0.6628358009827975	[300,365]	[99,404]	3	hSpCas9	positive selection	2955830
56886042	56886065	5	+	27013184	SW480	treatment with recombinant TRAIL	ATCATTCACAGAGATGTCAAAGG	MAP3K1	ENSG00000095015	0.3391158596623907	[95,220]	[73,96]	1	hSpCas9	positive selection	2955831
56815762	56815785	5	+	27013184	SW480	treatment with recombinant TRAIL	CAAAGTGCGGAGTGTGGAGCTGG	MAP3K1	ENSG00000095015	-0.12702001322740086	[1429,1514]	[411,819]	0	hSpCas9	positive selection	2955832
56885968	56885991	5	-	27013184	SW480	treatment with recombinant TRAIL	AATAACTACTGATTCTTTGAAGG	MAP3K1	ENSG00000095015	0.22712174976631294	[94,114]	[52,51]	1	hSpCas9	positive selection	2955847
56815933	56815956	5	+	27013184	SW480	treatment with recombinant TRAIL	CGGCGCCCACCTTACCGAGTCGG	MAP3K1	ENSG00000095015	-0.7929268810078156	[736,1116]	[158,322]	-4	hSpCas9	positive selection	2955848
56815936	56815959	5	+	27013184	SW480	treatment with recombinant TRAIL	CGCCCACCTTACCGAGTCGGTGG	MAP3K1	ENSG00000095015	0.49127609699309543	[229,252]	[71,250]	2	hSpCas9	positive selection	2955849
56815939	56815962	5	+	27013184	SW480	treatment with recombinant TRAIL	CCACCTTACCGAGTCGGTGGCGG	MAP3K1	ENSG00000095015	0.18099235582317053	[433,674]	[303,211]	0	hSpCas9	positive selection	2955855
56885943	56885966	5	+	27013184	SW480	treatment with recombinant TRAIL	GCTCATTTGCTGAGTAAATATGG	MAP3K1	ENSG00000095015	0.4988947300805757	[452,529]	[276,326]	2	hSpCas9	positive selection	2955857
56885994	56886017	5	+	27013184	SW480	treatment with recombinant TRAIL	TACACTGAACAGTTACTCCGTGG	MAP3K1	ENSG00000095015	1.6675782287479555	[74,47]	[132,18]	7	hSpCas9	positive selection	2955858
56886038	56886061	5	-	27013184	SW480	treatment with recombinant TRAIL	TGACATCTCTGTGAATGATTTGG	MAP3K1	ENSG00000095015	-0.6951867352709091	[494,387]	[120,115]	-3	hSpCas9	positive selection	2955859
56864913	56864936	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.3147955446749715	[4,4]	[4,4]	6	hSpCas9	positive selection	3001128
56864785	56864808	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCTCACCATATAGCCCTGAGG	MAP3K1	ENSG00000095015	0.5633239907276846	[5,5]	[5,8]	9	hSpCas9	positive selection	3001129
56864814	56864837	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATCACTTTGTTAACACGGCGG	MAP3K1	ENSG00000095015	0.25418120323509985	[4,4]	[4,3]	5	hSpCas9	positive selection	3001130
56864913	56864936	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.26221374852637314	[4,4]	[4,3]	4	hSpCas9	positive selection	3068986
56864785	56864808	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCTCACCATATAGCCCTGAGG	MAP3K1	ENSG00000095015	0.2953130299961171	[5,5]	[5,4]	5	hSpCas9	positive selection	3068987
56864814	56864837	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATCACTTTGTTAACACGGCGG	MAP3K1	ENSG00000095015	-0.2844586010193726	[4,4]	[3,1]	-4	hSpCas9	positive selection	3068988
56864817	56864840		-	24336571	A375	resistance to PLX after 7 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	-0.13821962245172914	[29,29]	[27,25]	-4	hSpCas9	positive selection	3126267
56864816	56864839		+	24336571	A375	resistance to PLX after 7 days	GCCGTGTTAACAAAGTGATGCGG	MAP3K1	ENSG00000095015	-0.1409845833496024	[8,9]	[8,7]	-4	hSpCas9	positive selection	3126268
56864817	56864840		-	24336571	A375	resistance to PLX after 14 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.44021964881868003	[28,26]	[16,18]	4	hSpCas9	positive selection	3184060
56864816	56864839		+	24336571	A375	resistance to PLX after 14 days	GCCGTGTTAACAAAGTGATGCGG	MAP3K1	ENSG00000095015	-0.3876087554732658	[8,5]	[1,1]	-4	hSpCas9	positive selection	3184061
56864817	56864840		-	24336571	A375	viability after 7 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.07867475197921814	[29]	[29,29]	1	hSpCas9	negative selection	3241853
56864816	56864839		+	24336571	A375	viability after 7 days	GCCGTGTTAACAAAGTGATGCGG	MAP3K1	ENSG00000095015	-0.27517773972641824	[11]	[8,9]	-4	hSpCas9	negative selection	3241854
56864817	56864840		-	24336571	A375	viability after 14 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.007442250014474627	[29]	[28,26]	0	hSpCas9	negative selection	3299646
56864816	56864839		+	24336571	A375	viability after 14 days	GCCGTGTTAACAAAGTGATGCGG	MAP3K1	ENSG00000095015	-0.5258452766221401	[11]	[8,5]	-6	hSpCas9	negative selection	3299647
56865393	56865416	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	1.1280431945008687	[69,69]	[0,0]	5	hSpCas9	positive selection	3378391
56865410	56865433	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	-0.9714924790500457	[299,299]	[0,0]	-6	hSpCas9	positive selection	3378392
56864913	56864936	5	-	26780180	HT29	viability (Avana library 4 designs)	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	-0.0436632609408234	[]	[]	0	hSpCas9	negative selection	3438772
56864784	56864807	5	+	26780180	HT29	viability (Avana library 4 designs)	CTTCTCACCATATAGCCCTGAGG	MAP3K1	ENSG00000095015	-0.0780198660194209	[]	[]	-1	hSpCas9	negative selection	3438773
56864814	56864837	5	-	26780180	HT29	viability (Avana library 4 designs)	GCATCACTTTGTTAACACGGCGG	MAP3K1	ENSG00000095015	0.471276127196867	[]	[]	1	hSpCas9	negative selection	3438774
56864814	56864837	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATCACTTTGTTAACACGGCGG	MAP3K1	ENSG00000095015	-1.62571384816081	[]	[]	-2	hSpCas9	negative selection	3528187
56864913	56864936	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	2.62294888348734	[]	[]	4	hSpCas9	negative selection	3528188
56864784	56864807	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCTCACCATATAGCCCTGAGG	MAP3K1	ENSG00000095015	0.700498519291644	[]	[]	1	hSpCas9	negative selection	3528189
56815972	56815995	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGGCGCCTCGAGTCCCGCAGCGG	MAP3K1	ENSG00000095015	0.835898854505016	[]	[]	1	hSpCas9	negative selection	3528190
56815692	56815715	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGCCTCCCGCAGCAGTCCCGCGG	MAP3K1	ENSG00000095015	2.86032757049324	[]	[]	4	hSpCas9	negative selection	3528191
56864814	56864837	5	-	26780180	A375	viability (Avana lentiGuide)	GCATCACTTTGTTAACACGGCGG	MAP3K1	ENSG00000095015	-1.32340758497889	[]	[]	-2	hSpCas9	negative selection	3636846
56864913	56864936	5	-	26780180	A375	viability (Avana lentiGuide)	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	-1.38466495219192	[]	[]	-2	hSpCas9	negative selection	3636847
56864784	56864807	5	+	26780180	A375	viability (Avana lentiGuide)	CTTCTCACCATATAGCCCTGAGG	MAP3K1	ENSG00000095015	-0.372596992832672	[]	[]	0	hSpCas9	negative selection	3636848
56815972	56815995	5	+	26780180	A375	viability (Avana lentiGuide)	CGGCGCCTCGAGTCCCGCAGCGG	MAP3K1	ENSG00000095015	7.78794856503878	[]	[]	6	hSpCas9	negative selection	3636849
56815692	56815715	5	-	26780180	A375	viability (Avana lentiGuide)	CGCCTCCCGCAGCAGTCCCGCGG	MAP3K1	ENSG00000095015	4.72295321453954	[]	[]	4	hSpCas9	negative selection	3636850
56864814	56864837	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATCACTTTGTTAACACGGCGG	MAP3K1	ENSG00000095015	-0.20987429845692646	[6]	[5,4]	-3	hSpCas9	positive selection	3745505
56864913	56864936	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.06916649336233668	[5]	[5,5]	1	hSpCas9	positive selection	3745506
56864784	56864807	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCTCACCATATAGCCCTGAGG	MAP3K1	ENSG00000095015	0.07496808030607716	[6]	[6,6]	2	hSpCas9	positive selection	3745507
56815972	56815995	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGCGCCTCGAGTCCCGCAGCGG	MAP3K1	ENSG00000095015	0.07787350467332244	[2]	[3,1]	2	hSpCas9	positive selection	3745508
56815692	56815715	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGCCTCCCGCAGCAGTCCCGCGG	MAP3K1	ENSG00000095015	0.0058697842446551185	[3]	[3,2]	0	hSpCas9	positive selection	3745509
56864814	56864837	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATCACTTTGTTAACACGGCGG	MAP3K1	ENSG00000095015	0.07847526762586812	[6]	[5,5]	1	hSpCas9	positive selection	3854112
56864913	56864936	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.24693176585150578	[6]	[6,5]	6	hSpCas9	positive selection	3854113
56864784	56864807	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCTCACCATATAGCCCTGAGG	MAP3K1	ENSG00000095015	0.21139433993934198	[7]	[7,6]	5	hSpCas9	positive selection	3854114
56815972	56815995	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGCGCCTCGAGTCCCGCAGCGG	MAP3K1	ENSG00000095015	-0.5059772947308364	[4]	[0,3]	-6	hSpCas9	positive selection	3854115
56815692	56815715	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGCCTCCCGCAGCAGTCCCGCGG	MAP3K1	ENSG00000095015	-0.33633875620231857	[4]	[0,5]	-4	hSpCas9	positive selection	3854116
56865410	56865433	5	+	26780180	A375	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.765459074195675	[]	[]	3	hSpCas9	negative selection	3959627
56865393	56865416	5	-	26780180	A375	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	1.29354640341686	[]	[]	7	hSpCas9	negative selection	3959628
56864817	56864840	5	-	26780180	A375	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.992766182229188	[]	[]	4	hSpCas9	negative selection	3959629
56864913	56864936	5	-	26780180	A375	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	1.22103061094653	[]	[]	6	hSpCas9	negative selection	3959630
56865410	56865433	5	+	26780180	HT29	viability (GeCKOv2 library)	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.422284643626331	[]	[]	1	hSpCas9	negative selection	4067593
56865393	56865416	5	-	26780180	HT29	viability (GeCKOv2 library)	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	1.09932959709492	[]	[]	5	hSpCas9	negative selection	4067594
56864817	56864840	5	-	26780180	HT29	viability (GeCKOv2 library)	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.546642587427946	[]	[]	1	hSpCas9	negative selection	4067595
56864913	56864936	5	-	26780180	HT29	viability (GeCKOv2 library)	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.537705338310276	[]	[]	1	hSpCas9	negative selection	4067596
56864817	56864840	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.23409705680520093	[4]	[3,4]	6	hSpCas9	positive selection	4150484
56864816	56864839	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCGTGTTAACAAAGTGATGCGG	MAP3K1	ENSG00000095015	-0.43540178187276024	[3]	[1,0]	-8	hSpCas9	positive selection	4150485
56864817	56864840	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	1.1196273905757712	[5]	[4,4,5,4]	8	hSpCas9	positive selection	4214506
56864816	56864839	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCGTGTTAACAAAGTGATGCGG	MAP3K1	ENSG00000095015	-0.6046730880398031	[3]	[0,0,1,0]	-8	hSpCas9	positive selection	4214507
56864817	56864840	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.14446187174021868	[2]	[2,1]	3	hSpCas9	positive selection	4281820
56864913	56864936	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	-0.08226040869054808	[3]	[3,1]	-2	hSpCas9	positive selection	4281821
56870164	56870187	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	-0.33810592845598475	[3]	[2,0]	-6	hSpCas9	positive selection	4315696
56865393	56865416	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.24932945240393406	[2]	[2,0]	-5	hSpCas9	positive selection	4346077
56865410	56865433	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.22705221766852401	[3]	[4,2]	4	hSpCas9	positive selection	4346078
56815938	56815960	5	-	27760321	OCIAML3	viability	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.617002409447045	[557,542]	[524,839]	7	hSpCas9	negative selection	4416575
56879010	56879032	5	-	27760321	OCIAML3	viability	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	0.46547040591441347	[711,641]	[610,885]	5	hSpCas9	negative selection	4416576
56864914	56864936	5	+	27760321	OCIAML3	viability	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	-0.13330289459674283	[425,391]	[288,294]	-1	hSpCas9	negative selection	4416577
56875281	56875303	5	-	27760321	OCIAML3	viability	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	-0.35676520832944614	[279,220]	[105,211]	-4	hSpCas9	negative selection	4416578
56815938	56815960	5	-	27760321	OCIAML2	viability	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.39712493947476096	[557,542]	[544,643]	5	hSpCas9	negative selection	4500038
56879010	56879032	5	-	27760321	OCIAML2	viability	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	0.49600243053238	[711,641]	[699,865]	6	hSpCas9	negative selection	4500039
56864914	56864936	5	+	27760321	OCIAML2	viability	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	0.326328255421823	[425,391]	[340,511]	4	hSpCas9	negative selection	4500040
56875281	56875303	5	-	27760321	OCIAML2	viability	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	-0.2533323580764799	[279,220]	[158,181]	-3	hSpCas9	negative selection	4500041
56815938	56815960	5	-	27760321	MV411	viability	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.44533485819539137	[557,542]	[396,643]	3	hSpCas9	negative selection	4583501
56879010	56879032	5	-	27760321	MV411	viability	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	-0.009176723615748394	[711,641]	[315,634]	0	hSpCas9	negative selection	4583502
56864914	56864936	5	+	27760321	MV411	viability	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	-0.3138262062718792	[425,391]	[105,383]	-2	hSpCas9	negative selection	4583503
56875281	56875303	5	-	27760321	MV411	viability	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	0.3100574792116363	[279,220]	[239,148]	2	hSpCas9	negative selection	4583504
56815938	56815960	5	-	27760321	HL60	viability	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.17744750587212604	[557,542]	[497,521]	2	hSpCas9	negative selection	4666964
56879010	56879032	5	-	27760321	HL60	viability	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	0.38719838951518337	[711,641]	[774,666]	5	hSpCas9	negative selection	4666965
56864914	56864936	5	+	27760321	HL60	viability	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	0.6440922413143081	[425,391]	[440,607]	7	hSpCas9	negative selection	4666966
56875281	56875303	5	-	27760321	HL60	viability	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	0.3745313112132478	[279,220]	[249,277]	4	hSpCas9	negative selection	4666967
56815938	56815960	5	-	27760321	HT1080	viability	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.8203685206815745	[542,423]	[342,336]	4	hSpCas9	negative selection	4750427
56879010	56879032	5	-	27760321	HT1080	viability	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	-0.25090800560248355	[641,500]	[155,229]	-1	hSpCas9	negative selection	4750428
56864914	56864936	5	+	27760321	HT1080	viability	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	0.18491110277357728	[391,305]	[158,156]	0	hSpCas9	negative selection	4750429
56875281	56875303	5	-	27760321	HT1080	viability	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	1.0474871316638246	[220,172]	[82,248]	5	hSpCas9	negative selection	4750430
56815938	56815960	5	-	27760321	HT29	viability after 7 days	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.42942965336026867	[542,423]	[817,927,763]	6	hSpCas9	negative selection	4833890
56879010	56879032	5	-	27760321	HT29	viability after 7 days	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	0.07308798985796783	[641,500]	[714,741,849]	1	hSpCas9	negative selection	4833891
56864914	56864936	5	+	27760321	HT29	viability after 7 days	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	-0.18482723668022732	[391,305]	[493,376,328]	-3	hSpCas9	negative selection	4833892
56875281	56875303	5	-	27760321	HT29	viability after 7 days	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	-0.5253685804832116	[220,172]	[305,117,123]	-6	hSpCas9	negative selection	4833893
56815938	56815960	5	-	27760321	HT29	viability after 25 days	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.7653930498054471	[542,423]	[823,824,1201]	8	hSpCas9	negative selection	4917353
56879010	56879032	5	-	27760321	HT29	viability after 25 days	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	0.45817131543814127	[641,500]	[1038,576,1084]	5	hSpCas9	negative selection	4917354
56864914	56864936	5	+	27760321	HT29	viability after 25 days	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	0.006533103597454834	[391,305]	[349,363,500]	0	hSpCas9	negative selection	4917355
56875281	56875303	5	-	27760321	HT29	viability after 25 days	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	0.10408934430192662	[220,172]	[175,258,300]	1	hSpCas9	negative selection	4917356
56815938	56815960	5	-	27760321	HT29	viability after 22 days	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.6593976525634184	[542,423]	[973,792,878]	7	hSpCas9	negative selection	5000816
56879010	56879032	5	-	27760321	HT29	viability after 22 days	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	0.2742465821960729	[641,500]	[834,760,799]	3	hSpCas9	negative selection	5000817
56864914	56864936	5	+	27760321	HT29	viability after 22 days	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	0.21674682967305176	[391,305]	[500,511,391]	2	hSpCas9	negative selection	5000818
56875281	56875303	5	-	27760321	HT29	viability after 22 days	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	-0.17297588008164344	[220,172]	[298,155,147]	-2	hSpCas9	negative selection	5000819
56815938	56815960	5	-	27760321	HT29	viability after 19 days	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.7309310885770977	[542,423]	[857,742,1136]	7	hSpCas9	negative selection	5084279
56879010	56879032	5	-	27760321	HT29	viability after 19 days	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	0.2677779823758044	[641,500]	[1066,628,696]	2	hSpCas9	negative selection	5084280
56864914	56864936	5	+	27760321	HT29	viability after 19 days	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	0.1704458302421255	[391,305]	[451,617,283]	1	hSpCas9	negative selection	5084281
56875281	56875303	5	-	27760321	HT29	viability after 19 days	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	-1.185449147426182	[220,172]	[165,60,77]	-7	hSpCas9	negative selection	5084282
56815938	56815960	5	-	27760321	HT29	viability after 16 days	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.7395444533496551	[542,423]	[737,821,1135]	8	hSpCas9	negative selection	5167742
56879010	56879032	5	-	27760321	HT29	viability after 16 days	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	0.24030832517091838	[641,500]	[941,653,689]	2	hSpCas9	negative selection	5167743
56864914	56864936	5	+	27760321	HT29	viability after 16 days	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	0.43546779295527227	[391,305]	[654,644,292]	5	hSpCas9	negative selection	5167744
56875281	56875303	5	-	27760321	HT29	viability after 16 days	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	0.8530200738094952	[220,172]	[413,435,344]	8	hSpCas9	negative selection	5167745
56815938	56815960	5	-	27760321	HT29	viability after 13 days	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.5434091344834668	[542,423]	[876,736,836]	7	hSpCas9	negative selection	5251205
56879010	56879032	5	-	27760321	HT29	viability after 13 days	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	0.3322603092729488	[641,500]	[956,802,748]	4	hSpCas9	negative selection	5251206
56864914	56864936	5	+	27760321	HT29	viability after 13 days	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	0.26661385286524175	[391,305]	[598,581,291]	3	hSpCas9	negative selection	5251207
56875281	56875303	5	-	27760321	HT29	viability after 13 days	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	0.10966922313034833	[220,172]	[282,247,210]	1	hSpCas9	negative selection	5251208
56815938	56815960	5	-	27760321	HT29	viability after 10 days	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.5542525236628848	[542,423]	[834,803,1014]	7	hSpCas9	negative selection	5334668
56879010	56879032	5	-	27760321	HT29	viability after 10 days	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	0.09181390244495347	[641,500]	[858,712,708]	1	hSpCas9	negative selection	5334669
56864914	56864936	5	+	27760321	HT29	viability after 10 days	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	0.4079751663389272	[391,305]	[583,747,410]	5	hSpCas9	negative selection	5334670
56875281	56875303	5	-	27760321	HT29	viability after 10 days	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	0.1986194533188712	[220,172]	[225,248,368]	2	hSpCas9	negative selection	5334671
56815938	56815960	5	-	27760321	MOLM13	viability	GCCACCGACTCGGTAAGGTGGG	MAP3K1	ENSG00000095015	0.4430361778801321	[557,542]	[595,275]	3	hSpCas9	negative selection	5418131
56879010	56879032	5	-	27760321	MOLM13	viability	TTTCCGCTAAACTGTGGCAAGG	MAP3K1	ENSG00000095015	0.7465119783906313	[711,641]	[670,613]	5	hSpCas9	negative selection	5418132
56864914	56864936	5	+	27760321	MOLM13	viability	CGGGTGTTTATTGGGCCTCAGG	MAP3K1	ENSG00000095015	-0.6015188805952537	[425,391]	[278,43]	-4	hSpCas9	negative selection	5418133
56875281	56875303	5	-	27760321	MOLM13	viability	CAACGTACACTTTGTAGACAGG	MAP3K1	ENSG00000095015	-0.5014718244853882	[279,220]	[109,89]	-3	hSpCas9	negative selection	5418134
56815599	56815622	5	-	27661255	K562	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	0.20678368215579876	[505,630]	[514,527]	7	dCas9-KRAB	negative selection	5492077
56815964	56815987	5	-	27661255	K562	viability	GGACTCGAGGCGCCGCTGTCCGG	MAP3K1	ENSG00000095015	-0.08981747977025972	[581,642]	[493,428]	-3	dCas9-KRAB	negative selection	5492078
56864817	56864840	5	-	27260156	BXPC3	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.11955696071979094	[343]	[339,392,389,449]	2	hSpCas9	negative selection	5554280
56864913	56864936	5	-	27260156	BXPC3	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.419497638280166	[487]	[605,672,694,770]	8	hSpCas9	negative selection	5554281
56870164	56870187	5	+	27260156	BXPC3	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.040154353130709586	[573]	[603,543,659,668]	0	hSpCas9	negative selection	5588156
56865393	56865416	5	-	27260156	BXPC3	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.04709366656242897	[311]	[355,275,298,328]	-1	hSpCas9	negative selection	5618537
56865410	56865433	5	+	27260156	BXPC3	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.20588673074164443	[730]	[887,847,842,949]	4	hSpCas9	negative selection	5618538
56864817	56864840	5	-	27260156	A673	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.34164155441002053	[343]	[576,473,482,568]	7	hSpCas9	negative selection	5675531
56864913	56864936	5	-	27260156	A673	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.44914857684270054	[487]	[731,765,767,932]	8	hSpCas9	negative selection	5675532
56870164	56870187	5	+	27260156	A673	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.03689177991656206	[573]	[876,676,606,685]	0	hSpCas9	negative selection	5709407
56865393	56865416	5	-	27260156	A673	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.002644057101771735	[311]	[390,389,368,344]	0	hSpCas9	negative selection	5739788
56865410	56865433	5	+	27260156	A673	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.1630694987788741	[730]	[1189,940,934,882]	4	hSpCas9	negative selection	5739789
56864817	56864840	5	-	27260156	A375	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.295789290949112	[343]	[442,878,437,288]	4	hSpCas9	negative selection	5796782
56864913	56864936	5	-	27260156	A375	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.7366183267193971	[487]	[1086,1153,701,888]	9	hSpCas9	negative selection	5796783
56870164	56870187	5	+	27260156	A375	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	-0.18494375971690752	[573]	[690,623,639,426]	-3	hSpCas9	negative selection	5830658
56865393	56865416	5	-	27260156	A375	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	0.2571509294125049	[311]	[344,584,408,422]	4	hSpCas9	negative selection	5861039
56865410	56865433	5	+	27260156	A375	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.2744597059559958	[730]	[1113,1084,859,1070]	4	hSpCas9	negative selection	5861040
56864817	56864840	5	-	27260156	COLO741	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.4109859472014922	[343]	[702,603,463]	8	hSpCas9	negative selection	5918033
56864913	56864936	5	-	27260156	COLO741	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.5290172980704089	[487]	[1086,856,777]	9	hSpCas9	negative selection	5918034
56870164	56870187	5	+	27260156	COLO741	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.2947087240458589	[573]	[1030,822,856]	6	hSpCas9	negative selection	5951909
56865393	56865416	5	-	27260156	COLO741	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.09275292017258563	[311]	[414,292,412]	-2	hSpCas9	negative selection	5982290
56865410	56865433	5	+	27260156	COLO741	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.3447754308006812	[730]	[1268,1293,1012]	7	hSpCas9	negative selection	5982291
56864817	56864840	5	-	27260156	CAL120	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.27660386653648694	[343]	[496,471,581]	4	hSpCas9	negative selection	6039284
56864913	56864936	5	-	27260156	CAL120	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.5011932542210122	[487]	[759,876,924]	7	hSpCas9	negative selection	6039285
56870164	56870187	5	+	27260156	CAL120	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.41424491423536147	[573]	[1367,778,773]	6	hSpCas9	negative selection	6073160
56865393	56865416	5	-	27260156	CAL120	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.09270693656679996	[311]	[359,395,335]	-1	hSpCas9	negative selection	6103541
56865410	56865433	5	+	27260156	CAL120	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.22894814804042063	[730]	[1059,1131,1005]	3	hSpCas9	negative selection	6103542
56864817	56864840	5	-	27260156	CADOES1	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.4778625357533603	[343]	[387,415,490,488]	7	hSpCas9	negative selection	6160535
56864913	56864936	5	-	27260156	CADOES1	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.3225947107169418	[487]	[592,582,637,451]	5	hSpCas9	negative selection	6160536
56870164	56870187	5	+	27260156	CADOES1	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	-0.01177749982872861	[573]	[581,493,482,559]	0	hSpCas9	negative selection	6194411
56865393	56865416	5	-	27260156	CADOES1	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.553582947891229	[311]	[139,252,227,168]	-7	hSpCas9	negative selection	6224792
56865410	56865433	5	+	27260156	CADOES1	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.5007318937702135	[730]	[857,1108,905,975]	8	hSpCas9	negative selection	6224793
56864817	56864840	5	-	27260156	EWS502	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.07523056214500368	[343]	[416,319,442,350]	1	hSpCas9	negative selection	6281786
56864913	56864936	5	-	27260156	EWS502	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.4968216274332455	[487]	[783,723,804,585]	8	hSpCas9	negative selection	6281787
56870164	56870187	5	+	27260156	EWS502	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.042194060520106935	[573]	[628,472,759,648]	0	hSpCas9	negative selection	6315662
56865393	56865416	5	-	27260156	EWS502	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.12828426956747974	[311]	[237,332,298,347]	-2	hSpCas9	negative selection	6346043
56865410	56865433	5	+	27260156	EWS502	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.36044407362156095	[730]	[972,986,1107,901]	6	hSpCas9	negative selection	6346044
56864817	56864840	5	-	27260156	EW8	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.33770103388977835	[343]	[311,346,397,338]	6	hSpCas9	negative selection	6403037
56864913	56864936	5	-	27260156	EW8	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.6674089090528295	[487]	[707,629,637,541]	9	hSpCas9	negative selection	6403038
56870164	56870187	5	+	27260156	EW8	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.062258795994427185	[573]	[688,409,447,422]	1	hSpCas9	negative selection	6436913
56865393	56865416	5	-	27260156	EW8	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.42587248293345803	[311]	[148,153,215,223]	-7	hSpCas9	negative selection	6467294
56865410	56865433	5	+	27260156	EW8	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.2756504243321579	[730]	[802,779,546,774]	5	hSpCas9	negative selection	6467295
56864817	56864840	5	-	27260156	CORL105	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.3786928299850404	[343]	[415,587,566,524]	7	hSpCas9	negative selection	6524288
56864913	56864936	5	-	27260156	CORL105	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.6157731877726291	[487]	[1006,894,967,650]	9	hSpCas9	negative selection	6524289
56870164	56870187	5	+	27260156	CORL105	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.024260440277066142	[573]	[716,717,595,688]	0	hSpCas9	negative selection	6558164
56865393	56865416	5	-	27260156	CORL105	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	0.05587399125834647	[311]	[395,299,426,404]	1	hSpCas9	negative selection	6588545
56865410	56865433	5	+	27260156	CORL105	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.05515728969972167	[730]	[741,1126,958,729]	1	hSpCas9	negative selection	6588546
56864817	56864840	5	-	27260156	HS294T	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.08772075196670237	[343]	[138,133,132,162]	1	hSpCas9	negative selection	6645539
56864913	56864936	5	-	27260156	HS294T	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	1.0850043635549922	[487]	[285,395,378,579]	9	hSpCas9	negative selection	6645540
56870164	56870187	5	+	27260156	HS294T	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.267028771874083	[573]	[291,278,243,245]	3	hSpCas9	negative selection	6679415
56865393	56865416	5	-	27260156	HS294T	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.33464537940117045	[311]	[49,114,140,76]	-5	hSpCas9	negative selection	6709796
56865410	56865433	5	+	27260156	HS294T	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.8102338251369038	[730]	[397,510,338,790]	9	hSpCas9	negative selection	6709797
56864817	56864840	5	-	27260156	HCC44	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	-0.09290837358315684	[343]	[453,408,377,223]	-1	hSpCas9	negative selection	6766790
56864913	56864936	5	-	27260156	HCC44	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.21359603555008924	[487]	[836,585,607,546]	3	hSpCas9	negative selection	6766791
56870164	56870187	5	+	27260156	HCC44	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.39562076468969176	[573]	[798,783,1119,759]	6	hSpCas9	negative selection	6800666
56865393	56865416	5	-	27260156	HCC44	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.3347270440810607	[311]	[272,191,387,293]	-5	hSpCas9	negative selection	6831047
56865410	56865433	5	+	27260156	HCC44	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.05732597868970468	[730]	[1028,746,1007,711]	0	hSpCas9	negative selection	6831048
56864817	56864840	5	-	27260156	G402	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.5750205866743491	[343]	[1170,501,538,370]	7	hSpCas9	negative selection	6888041
56864913	56864936	5	-	27260156	G402	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.5414241413635065	[487]	[998,800,1034,653]	6	hSpCas9	negative selection	6888042
56870164	56870187	5	+	27260156	G402	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	-0.21564163817504728	[573]	[521,795,641,456]	-3	hSpCas9	negative selection	6921917
56865393	56865416	5	-	27260156	G402	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.09658591901785574	[311]	[502,313,255,367]	-1	hSpCas9	negative selection	6952298
56865410	56865433	5	+	27260156	G402	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.6309573708888218	[730]	[1326,1358,1068,1737]	7	hSpCas9	negative selection	6952299
56864817	56864840	5	-	27260156	L33	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.251362316746357	[343]	[407,154,269,421]	5	hSpCas9	negative selection	7009292
56864913	56864936	5	-	27260156	L33	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.629506527794826	[487]	[742,317,522,669]	9	hSpCas9	negative selection	7009293
56870164	56870187	5	+	27260156	L33	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.31047839280434286	[573]	[732,309,447,644]	6	hSpCas9	negative selection	7043168
56865393	56865416	5	-	27260156	L33	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.19681843880565142	[311]	[211,107,170,341]	-4	hSpCas9	negative selection	7073549
56865410	56865433	5	+	27260156	L33	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.3286067118902066	[730]	[830,405,583,922]	7	hSpCas9	negative selection	7073550
56864817	56864840	5	-	27260156	K562	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.1931250556233874	[343]	[319,307,497,272]	2	hSpCas9	negative selection	7130543
56864913	56864936	5	-	27260156	K562	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.3653931777476445	[487]	[498,533,404,760]	4	hSpCas9	negative selection	7130544
56870164	56870187	5	+	27260156	K562	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.2865207094083141	[573]	[445,971,488,583]	3	hSpCas9	negative selection	7164419
56865393	56865416	5	-	27260156	K562	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.17791846378087717	[311]	[202,200,339,229]	-2	hSpCas9	negative selection	7194800
56865410	56865433	5	+	27260156	K562	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.09724228085226427	[730]	[1037,394,702,653]	1	hSpCas9	negative selection	7194801
56864817	56864840	5	-	27260156	HT29	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.2840154450389298	[343]	[527,496,612,407]	5	hSpCas9	negative selection	7251794
56864913	56864936	5	-	27260156	HT29	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.2533409125718111	[487]	[834,600,797,602]	5	hSpCas9	negative selection	7251795
56870164	56870187	5	+	27260156	HT29	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.13852323725584026	[573]	[938,960,684,539]	2	hSpCas9	negative selection	7285670
56865393	56865416	5	-	27260156	HT29	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	0.03183869900672731	[311]	[276,547,489,254]	0	hSpCas9	negative selection	7316051
56865410	56865433	5	+	27260156	HT29	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.1902996889316637	[730]	[1078,1214,874,913]	3	hSpCas9	negative selection	7316052
56864817	56864840	5	-	27260156	MHHES1	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.5622448990167868	[343]	[711,773,493,377]	8	hSpCas9	negative selection	7373045
56864913	56864936	5	-	27260156	MHHES1	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.6587080156139993	[487]	[680,1049,1129,640]	9	hSpCas9	negative selection	7373046
56870164	56870187	5	+	27260156	MHHES1	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.03655939500102229	[573]	[811,814,654,440]	0	hSpCas9	negative selection	7406921
56865393	56865416	5	-	27260156	MHHES1	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.009025970894058433	[311]	[250,426,449,274]	0	hSpCas9	negative selection	7437302
56865410	56865433	5	+	27260156	MHHES1	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.2380756548203128	[730]	[1107,1089,818,890]	4	hSpCas9	negative selection	7437303
56864817	56864840	5	-	27260156	MEWO	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.41885314657344147	[343]	[450,361,481]	8	hSpCas9	negative selection	7494296
56864913	56864936	5	-	27260156	MEWO	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.4317077600172734	[487]	[874,516,505]	8	hSpCas9	negative selection	7494297
56870164	56870187	5	+	27260156	MEWO	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.020336328570556783	[573]	[760,483,430]	0	hSpCas9	negative selection	7528172
56865393	56865416	5	-	27260156	MEWO	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	0.2173821095330119	[311]	[522,255,274]	5	hSpCas9	negative selection	7558553
56865410	56865433	5	+	27260156	MEWO	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.3136951672214846	[730]	[853,972,722]	6	hSpCas9	negative selection	7558554
56864817	56864840	5	-	27260156	LNCAPCLONEFGC	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.2183642407308309	[343]	[376,252,504,342]	3	hSpCas9	negative selection	7615547
56864913	56864936	5	-	27260156	LNCAPCLONEFGC	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.3723420077497239	[487]	[596,470,681,560]	6	hSpCas9	negative selection	7615548
56870164	56870187	5	+	27260156	LNCAPCLONEFGC	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.16330535635849852	[573]	[697,439,663,545]	2	hSpCas9	negative selection	7649423
56865393	56865416	5	-	27260156	LNCAPCLONEFGC	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.1537896156010582	[311]	[227,255,311,228]	-2	hSpCas9	negative selection	7679804
56865410	56865433	5	+	27260156	LNCAPCLONEFGC	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.4130033802199148	[730]	[1125,631,1010,787]	6	hSpCas9	negative selection	7679805
56864817	56864840	5	-	27260156	PANC0327	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.45478649017566575	[343]	[255,436,686,279]	6	hSpCas9	negative selection	7736798
56864913	56864936	5	-	27260156	PANC0327	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.19002599976637394	[487]	[942,250,389,461]	3	hSpCas9	negative selection	7736799
56870164	56870187	5	+	27260156	PANC0327	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	-0.23573495369538133	[573]	[771,231,530,250]	-4	hSpCas9	negative selection	7770674
56865393	56865416	5	-	27260156	PANC0327	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.17641168559655396	[311]	[168,228,362,215]	-3	hSpCas9	negative selection	7801055
56865410	56865433	5	+	27260156	PANC0327	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.3222630828487685	[730]	[663,833,718,1014]	5	hSpCas9	negative selection	7801056
56864817	56864840	5	-	27260156	NCIH2009	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.35900534178563404	[343]	[708,478,680]	5	hSpCas9	negative selection	7858049
56864913	56864936	5	-	27260156	NCIH2009	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.6573523344488573	[487]	[1215,1130,903]	8	hSpCas9	negative selection	7858050
56870164	56870187	5	+	27260156	NCIH2009	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	-0.0455676336650373	[573]	[771,599,959]	0	hSpCas9	negative selection	7891925
56865393	56865416	5	-	27260156	NCIH2009	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.03258406840692851	[311]	[446,366,468]	0	hSpCas9	negative selection	7922306
56865410	56865433	5	+	27260156	NCIH2009	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.06979975344418465	[730]	[969,954,1270]	1	hSpCas9	negative selection	7922307
56864817	56864840	5	-	27260156	NCIH1373	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.16272358120749275	[343]	[563,280,547,94]	1	hSpCas9	negative selection	7979300
56864913	56864936	5	-	27260156	NCIH1373	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.5633377103771736	[487]	[878,1047,468,216]	5	hSpCas9	negative selection	7979301
56870164	56870187	5	+	27260156	NCIH1373	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	-0.13050049904021813	[573]	[772,660,433,130]	-1	hSpCas9	negative selection	8013176
56865393	56865416	5	-	27260156	NCIH1373	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	0.030066411977056506	[311]	[140,248,716,74]	0	hSpCas9	negative selection	8043557
56865410	56865433	5	+	27260156	NCIH1373	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.3929331169297804	[730]	[919,1217,878,329]	4	hSpCas9	negative selection	8043558
56864817	56864840	5	-	27260156	PATU8902	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.30148385225803953	[343]	[768,627,486,484]	3	hSpCas9	negative selection	8100551
56864913	56864936	5	-	27260156	PATU8902	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.57283053494797	[487]	[771,1250,1102,872]	6	hSpCas9	negative selection	8100552
56870164	56870187	5	+	27260156	PATU8902	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	-0.517535318420328	[573]	[453,515,583,684]	-5	hSpCas9	negative selection	8134427
56865393	56865416	5	-	27260156	PATU8902	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	0.711886967247229	[311]	[298,561,531,1606]	7	hSpCas9	negative selection	8164808
56865410	56865433	5	+	27260156	PATU8902	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.37015121443017585	[730]	[1871,1216,954,1291]	4	hSpCas9	negative selection	8164809
56864817	56864840	5	-	27260156	PANC1	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.5145470530781084	[343]	[287,390,484,500]	8	hSpCas9	negative selection	8221802
56864913	56864936	5	-	27260156	PANC1	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.7728578248752502	[487]	[730,697,858,583]	9	hSpCas9	negative selection	8221803
56870164	56870187	5	+	27260156	PANC1	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.1580410452675478	[573]	[643,651,458,467]	2	hSpCas9	negative selection	8255678
56865393	56865416	5	-	27260156	PANC1	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	0.10532210311829426	[311]	[261,344,434,143]	1	hSpCas9	negative selection	8286059
56865410	56865433	5	+	27260156	PANC1	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.10284146935772731	[730]	[578,704,659,738]	1	hSpCas9	negative selection	8286060
56864817	56864840	5	-	27260156	PANC0813	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.2639252848396165	[343]	[600,469,492,391]	4	hSpCas9	negative selection	8343053
56864913	56864936	5	-	27260156	PANC0813	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.7846189762095815	[487]	[1294,715,913,1047]	9	hSpCas9	negative selection	8343054
56870164	56870187	5	+	27260156	PANC0813	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	-0.02084518948252906	[573]	[718,571,835,542]	0	hSpCas9	negative selection	8376929
56865393	56865416	5	-	27260156	PANC0813	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.1541235971755558	[311]	[291,306,338,372]	-3	hSpCas9	negative selection	8407310
56865410	56865433	5	+	27260156	PANC0813	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.3317924090488873	[730]	[1122,995,1242,969]	5	hSpCas9	negative selection	8407311
56864817	56864840	5	-	27260156	RDES	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.4481991077073241	[343]	[504,521,554,573]	7	hSpCas9	negative selection	8464304
56864913	56864936	5	-	27260156	RDES	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.5817696529110644	[487]	[697,718,967,1024]	8	hSpCas9	negative selection	8464305
56870164	56870187	5	+	27260156	RDES	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.2331356469706829	[573]	[665,703,1010,730]	4	hSpCas9	negative selection	8498180
56865393	56865416	5	-	27260156	RDES	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	0.038293071682618196	[311]	[309,348,452,367]	0	hSpCas9	negative selection	8528561
56865410	56865433	5	+	27260156	RDES	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.4444130324156951	[730]	[955,1035,1247,1393]	7	hSpCas9	negative selection	8528562
56864817	56864840	5	-	27260156	PC3	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.5028435478684826	[343]	[318,406,729,616]	8	hSpCas9	negative selection	8585555
56864913	56864936	5	-	27260156	PC3	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.6347377434901489	[487]	[556,686,1144,790]	9	hSpCas9	negative selection	8585556
56870164	56870187	5	+	27260156	PC3	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	-0.20755111090814443	[573]	[342,474,629,605]	-5	hSpCas9	negative selection	8619431
56865393	56865416	5	-	27260156	PC3	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.16992997398036158	[311]	[170,227,462,341]	-4	hSpCas9	negative selection	8649812
56865410	56865433	5	+	27260156	PC3	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.2873743115388282	[730]	[657,683,1721,828]	6	hSpCas9	negative selection	8649813
56864817	56864840	5	-	27260156	PATU8988T	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.21012370392315372	[343]	[379,287,325,548]	3	hSpCas9	negative selection	8706806
56864913	56864936	5	-	27260156	PATU8988T	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.4789301488783689	[487]	[506,762,640,733]	7	hSpCas9	negative selection	8706807
56870164	56870187	5	+	27260156	PATU8988T	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.16421884022825678	[573]	[752,826,303,625]	3	hSpCas9	negative selection	8740682
56865393	56865416	5	-	27260156	PATU8988T	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	0.21793484701917898	[311]	[235,465,332,380]	4	hSpCas9	negative selection	8771063
56865410	56865433	5	+	27260156	PATU8988T	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.23493702523717608	[730]	[877,1124,627,714]	4	hSpCas9	negative selection	8771064
56864817	56864840	5	-	27260156	T47D	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.4476917254525911	[343]	[493,524,571,597]	8	hSpCas9	negative selection	8828057
56864913	56864936	5	-	27260156	T47D	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.5153927976250839	[487]	[892,695,837,833]	9	hSpCas9	negative selection	8828058
56870164	56870187	5	+	27260156	T47D	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.12918960513633798	[573]	[734,724,645,823]	2	hSpCas9	negative selection	8861933
56865393	56865416	5	-	27260156	T47D	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.14485921315327588	[311]	[363,275,315,364]	-3	hSpCas9	negative selection	8892314
56865410	56865433	5	+	27260156	T47D	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.22848907740894686	[730]	[992,1004,1055,932]	5	hSpCas9	negative selection	8892315
56864817	56864840	5	-	27260156	SU8686	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	-0.3194326350003749	[343]	[244,221,298,347]	-5	hSpCas9	negative selection	8949308
56864913	56864936	5	-	27260156	SU8686	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.5542034561078016	[487]	[615,665,685,917]	8	hSpCas9	negative selection	8949309
56870164	56870187	5	+	27260156	SU8686	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.18243288164809557	[573]	[578,618,594,823]	3	hSpCas9	negative selection	8983184
56865393	56865416	5	-	27260156	SU8686	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.4090994545880301	[311]	[239,233,232,219]	-6	hSpCas9	negative selection	9013565
56865410	56865433	5	+	27260156	SU8686	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.11045422802445537	[730]	[640,788,819,910]	1	hSpCas9	negative selection	9013566
56864817	56864840	5	-	27260156	SKES1	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.3157312057668076	[343]	[496,514,421,304]	6	hSpCas9	negative selection	9070559
56864913	56864936	5	-	27260156	SKES1	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.3297780598946529	[487]	[658,628,610,556]	7	hSpCas9	negative selection	9070560
56870164	56870187	5	+	27260156	SKES1	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.2414591834343971	[573]	[773,648,669,623]	5	hSpCas9	negative selection	9104435
56865393	56865416	5	-	27260156	SKES1	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	0.18106022711277003	[311]	[455,377,296,300]	4	hSpCas9	negative selection	9134816
56865410	56865433	5	+	27260156	SKES1	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.38610308507583413	[730]	[1184,945,1076,658]	7	hSpCas9	negative selection	9134817
56864817	56864840	5	-	27260156	TOV112D	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.2993741357903155	[343]	[264,682,351,444]	6	hSpCas9	negative selection	9191810
56864913	56864936	5	-	27260156	TOV112D	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.5400351890436357	[487]	[627,859,663,718]	8	hSpCas9	negative selection	9191811
56870164	56870187	5	+	27260156	TOV112D	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.12204671091369351	[573]	[633,694,698,494]	2	hSpCas9	negative selection	9225686
56865393	56865416	5	-	27260156	TOV112D	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.5769131980695311	[311]	[171,285,211,183]	-8	hSpCas9	negative selection	9256067
56865410	56865433	5	+	27260156	TOV112D	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.1518323994790961	[730]	[696,592,1042,853]	3	hSpCas9	negative selection	9256068
56864817	56864840	5	-	27260156	TC71	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.3473852332035955	[343]	[510,415,421,531]	8	hSpCas9	negative selection	9313061
56864913	56864936	5	-	27260156	TC71	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.18378667400516596	[487]	[564,544,598,672]	4	hSpCas9	negative selection	9313062
56870164	56870187	5	+	27260156	TC71	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	0.03741150709572988	[573]	[634,788,572,523]	1	hSpCas9	negative selection	9346937
56865393	56865416	5	-	27260156	TC71	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	-0.15454859692915124	[311]	[318,323,296,258]	-4	hSpCas9	negative selection	9377318
56865410	56865433	5	+	27260156	TC71	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.20620247101988554	[730]	[839,963,959,847]	5	hSpCas9	negative selection	9377319
56864817	56864840	5	-	27260156	TC32	viability	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.5713841963447016	[343]	[413,375,543,625]	8	hSpCas9	negative selection	9434312
56864913	56864936	5	-	27260156	TC32	viability	CCTGAGGCCCAATAAACACCCGG	MAP3K1	ENSG00000095015	0.6396010135583988	[487]	[727,635,767,716]	9	hSpCas9	negative selection	9434313
56870164	56870187	5	+	27260156	TC32	viability	TTGCACCAACCTAATAGTTTAAG	MAP3K1	ENSG00000095015	-0.16300053665804362	[573]	[364,457,674,454]	-3	hSpCas9	negative selection	9468188
56865393	56865416	5	-	27260156	TC32	viability	AAGGTTCTAGTTGAAACACCCGG	MAP3K1	ENSG00000095015	0.10110331859836469	[311]	[332,244,309,376]	1	hSpCas9	negative selection	9498569
56865410	56865433	5	+	27260156	TC32	viability	AACCTTCAGACCCAATGTTATGG	MAP3K1	ENSG00000095015	0.2421499352982649	[730]	[926,546,1038,812]	4	hSpCas9	negative selection	9498570
56815628	56815651	5	+	27869803	HPAFII	viability after 27 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.09242950635579095	[65]	[49,17,NaN]	0	hSpCas9	negative selection	9592191
56864817	56864840	5	-	27869803	HPAFII	viability after 27 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.8528284434026512	[973]	[1196,697,NaN]	7	hSpCas9	negative selection	9592192
56865883	56865906	5	-	27869803	HPAFII	viability after 27 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	0.026713646394954965	[238]	[139,117,NaN]	0	hSpCas9	negative selection	9592193
56872896	56872919	5	+	27869803	HPAFII	viability after 27 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.08726131990498986	[150]	[65,81,NaN]	0	hSpCas9	negative selection	9592194
56815628	56815651	5	+	27869803	HPAFII	viability after 15 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.9838345389846033	[65]	[25,41,NaN]	-7	hSpCas9	negative selection	9674640
56864817	56864840	5	-	27869803	HPAFII	viability after 15 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.7433577586207547	[973]	[2368,1368,NaN]	8	hSpCas9	negative selection	9674641
56865883	56865906	5	-	27869803	HPAFII	viability after 15 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	0.06718969366043717	[238]	[331,229,NaN]	0	hSpCas9	negative selection	9674642
56872896	56872919	5	+	27869803	HPAFII	viability after 15 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.011889668810305065	[150]	[184,145,NaN]	0	hSpCas9	negative selection	9674643
56815628	56815651	5	+	27869803	ASPC1	viability after 36 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.09775161192122273	[187]	[107,93,1]	-1	hSpCas9	negative selection	9757089
56864817	56864840	5	-	27869803	ASPC1	viability after 36 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.43173936271534785	[2290]	[1229,1204,860]	4	hSpCas9	negative selection	9757090
56865883	56865906	5	-	27869803	ASPC1	viability after 36 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-0.44825317775896845	[768]	[156,398,61]	-4	hSpCas9	negative selection	9757091
56872896	56872919	5	+	27869803	ASPC1	viability after 36 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.3653648908423157	[432]	[7,203,123]	-4	hSpCas9	negative selection	9757092
56815628	56815651	5	+	27869803	PATU8988S	viability after 35 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.3363977781173355	[203]	[96,32,NaN]	-4	hSpCas9	negative selection	9839538
56864817	56864840	5	-	27869803	PATU8988S	viability after 35 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.6955896398511978	[2326]	[1446,1588,NaN]	7	hSpCas9	negative selection	9839539
56865883	56865906	5	-	27869803	PATU8988S	viability after 35 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-0.5765546104441727	[627]	[214,123,NaN]	-5	hSpCas9	negative selection	9839540
56872896	56872919	5	+	27869803	PATU8988S	viability after 35 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	0.01639637877849548	[424]	[227,117,NaN]	0	hSpCas9	negative selection	9839541
56815628	56815651	5	+	27869803	PATU8988S	viability after 31 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	0.11751988464963059	[203]	[122,43,NaN]	1	hSpCas9	negative selection	9921987
56864817	56864840	5	-	27869803	PATU8988S	viability after 31 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.7810067234494267	[2326]	[1384,1860,NaN]	8	hSpCas9	negative selection	9921988
56865883	56865906	5	-	27869803	PATU8988S	viability after 31 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	-0.6000282342237441	[627]	[195,125,NaN]	-6	hSpCas9	negative selection	9921989
56872896	56872919	5	+	27869803	PATU8988S	viability after 31 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	-0.4897786873408678	[424]	[132,104,NaN]	-5	hSpCas9	negative selection	9921990
56815628	56815651	5	+	27869803	HPAFII	viability after 35 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-1.0943787890259917	[65]	[17,12,NaN]	-6	hSpCas9	negative selection	10004436
56864817	56864840	5	-	27869803	HPAFII	viability after 35 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	0.9761574066901866	[973]	[977,960,NaN]	6	hSpCas9	negative selection	10004437
56865883	56865906	5	-	27869803	HPAFII	viability after 35 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	0.1083628556482073	[238]	[168,86,NaN]	0	hSpCas9	negative selection	10004438
56872896	56872919	5	+	27869803	HPAFII	viability after 35 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	0.5107691016711355	[150]	[59,163,NaN]	3	hSpCas9	negative selection	10004439
56815628	56815651	5	+	27869803	HPAFII	viability after 31 days	GCTACGAGCCCTGAGGCAGGCGG	MAP3K1	ENSG00000095015	-0.9603861189816241	[65]	[30,5,NaN]	-6	hSpCas9	negative selection	10086885
56864817	56864840	5	-	27869803	HPAFII	viability after 31 days	CCCGCATCACTTTGTTAACACGG	MAP3K1	ENSG00000095015	1.023227063556531	[973]	[1121,1098,NaN]	7	hSpCas9	negative selection	10086886
56865883	56865906	5	-	27869803	HPAFII	viability after 31 days	TTCTGGATGGTGTTACGAGATGG	MAP3K1	ENSG00000095015	0.2140701811550518	[238]	[190,116,NaN]	1	hSpCas9	negative selection	10086887
56872896	56872919	5	+	27869803	HPAFII	viability after 31 days	AGCCTTTGGCTGGATCACGAAGG	MAP3K1	ENSG00000095015	0.36918875382909233	[150]	[74,146,NaN]	2	hSpCas9	negative selection	10086888
56815823	56815846	5	-	28162770	P31FUJ	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-2.7108495012190232	[38]	[6]	-9	hSpCas9	negative selection	10188717
56864755	56864778	5	-	28162770	P31FUJ	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-1.122619286663956	[62]	[33]	-7	hSpCas9	negative selection	10188718
56882106	56882129	5	-	28162770	P31FUJ	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.7500566627642273	[126]	[250]	8	hSpCas9	negative selection	10188719
56882803	56882826	5	-	28162770	P31FUJ	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	-0.01196023464133078	[265]	[309]	0	hSpCas9	negative selection	10188720
56815561	56815584	5	+	28162770	P31FUJ	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	0.640749460344682	[142]	[261]	7	hSpCas9	negative selection	10188721
56815599	56815622	5	-	28162770	P31FUJ	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	-1.504104226231773	[69]	[28]	-7	hSpCas9	negative selection	10188722
56815879	56815902	5	+	28162770	P31FUJ	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-0.5490615492150489	[253]	[203]	-4	hSpCas9	negative selection	10188723
56815823	56815846	5	-	28162770	TF1	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10358083
56864755	56864778	5	-	28162770	TF1	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10358084
56882106	56882129	5	-	28162770	TF1	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10358085
56882803	56882826	5	-	28162770	TF1	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10358086
56815561	56815584	5	+	28162770	TF1	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	NaN	[NaN]	[245]	1	hSpCas9	negative selection	10358087
56815599	56815622	5	-	28162770	TF1	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10358088
56815879	56815902	5	+	28162770	TF1	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10358089
56815823	56815846	5	-	28162770	SKM1	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-2.406964198743162	[8]	[2]	-8	hSpCas9	negative selection	10527449
56864755	56864778	5	-	28162770	SKM1	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	0.3035291840618535	[21]	[47]	3	hSpCas9	negative selection	10527450
56882106	56882129	5	-	28162770	SKM1	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.2829678615795371	[52]	[113]	2	hSpCas9	negative selection	10527451
56882803	56882826	5	-	28162770	SKM1	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	0.23328073747918415	[63]	[132]	2	hSpCas9	negative selection	10527452
56815561	56815584	5	+	28162770	SKM1	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	0.2407340573259571	[44]	[93]	2	hSpCas9	negative selection	10527453
56815599	56815622	5	-	28162770	SKM1	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	-1.2914869813232257	[17]	[12]	-7	hSpCas9	negative selection	10527454
56815879	56815902	5	+	28162770	SKM1	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-1.2814333166593026	[43]	[31]	-7	hSpCas9	negative selection	10527455
56815823	56815846	5	-	28162770	SKM1	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-2.406964198743162	[8]	[2]	-8	hSpCas9	negative selection	10696815
56864755	56864778	5	-	28162770	SKM1	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	0.3035291840618535	[21]	[47]	3	hSpCas9	negative selection	10696816
56882106	56882129	5	-	28162770	SKM1	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.2829678615795371	[52]	[113]	2	hSpCas9	negative selection	10696817
56882803	56882826	5	-	28162770	SKM1	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	0.23328073747918415	[63]	[132]	2	hSpCas9	negative selection	10696818
56815561	56815584	5	+	28162770	SKM1	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	0.2407340573259571	[44]	[93]	2	hSpCas9	negative selection	10696819
56815599	56815622	5	-	28162770	SKM1	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	-1.2914869813232257	[17]	[12]	-7	hSpCas9	negative selection	10696820
56815879	56815902	5	+	28162770	SKM1	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-1.2814333166593026	[43]	[31]	-7	hSpCas9	negative selection	10696821
56815823	56815846	5	-	28162770	PL21	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-3.0477878989542657	[18]	[0]	-9	hSpCas9	negative selection	10866181
56864755	56864778	5	-	28162770	PL21	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	0.6421441613684333	[52]	[35]	5	hSpCas9	negative selection	10866182
56882106	56882129	5	-	28162770	PL21	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.15528537870505965	[195]	[94]	1	hSpCas9	negative selection	10866183
56882803	56882826	5	-	28162770	PL21	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	-0.522326409981771	[263]	[79]	-4	hSpCas9	negative selection	10866184
56815561	56815584	5	+	28162770	PL21	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	0.46052929906755025	[181]	[108]	4	hSpCas9	negative selection	10866185
56815599	56815622	5	-	28162770	PL21	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	-1.7771403090105962	[62]	[7]	-8	hSpCas9	negative selection	10866186
56815879	56815902	5	+	28162770	PL21	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-0.7916398787057113	[174]	[43]	-5	hSpCas9	negative selection	10866187
56815823	56815846	5	-	28162770	P31FUJ	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-2.7108495012190232	[38]	[6]	-9	hSpCas9	negative selection	11035547
56864755	56864778	5	-	28162770	P31FUJ	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-1.122619286663956	[62]	[33]	-7	hSpCas9	negative selection	11035548
56882106	56882129	5	-	28162770	P31FUJ	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.7500566627642273	[126]	[250]	8	hSpCas9	negative selection	11035549
56882803	56882826	5	-	28162770	P31FUJ	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	-0.01196023464133078	[265]	[309]	0	hSpCas9	negative selection	11035550
56815561	56815584	5	+	28162770	P31FUJ	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	0.640749460344682	[142]	[261]	7	hSpCas9	negative selection	11035551
56815599	56815622	5	-	28162770	P31FUJ	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	-1.504104226231773	[69]	[28]	-7	hSpCas9	negative selection	11035552
56815879	56815902	5	+	28162770	P31FUJ	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-0.5490615492150489	[253]	[203]	-4	hSpCas9	negative selection	11035553
56815823	56815846	5	-	28162770	OCIAML5	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-4.437029071585153	[11]	[0]	-9	hSpCas9	negative selection	11204913
56864755	56864778	5	-	28162770	OCIAML5	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-0.714563047114062	[39]	[43]	-5	hSpCas9	negative selection	11204914
56882106	56882129	5	-	28162770	OCIAML5	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.5484713587197318	[74]	[197]	5	hSpCas9	negative selection	11204915
56882803	56882826	5	-	28162770	OCIAML5	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	-1.169548760720167	[161]	[129]	-6	hSpCas9	negative selection	11204916
56815561	56815584	5	+	28162770	OCIAML5	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	-0.28947188317129524	[64]	[95]	-2	hSpCas9	negative selection	11204917
56815599	56815622	5	-	28162770	OCIAML5	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	-0.11510097669779062	[20]	[34]	-1	hSpCas9	negative selection	11204918
56815879	56815902	5	+	28162770	OCIAML5	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-0.9800741832400685	[105]	[96]	-6	hSpCas9	negative selection	11204919
56815823	56815846	5	-	28162770	EOL1	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-1.3164603279332603	[51]	[10]	-7	hSpCas9	negative selection	11374279
56864755	56864778	5	-	28162770	EOL1	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	0.5276576190019502	[78]	[59]	5	hSpCas9	negative selection	11374280
56882106	56882129	5	-	28162770	EOL1	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.3139594631738839	[283]	[185]	3	hSpCas9	negative selection	11374281
56882803	56882826	5	-	28162770	EOL1	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	0.2329575422832028	[385]	[238]	2	hSpCas9	negative selection	11374282
56815561	56815584	5	+	28162770	EOL1	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	-0.5004738162809316	[289]	[107]	-4	hSpCas9	negative selection	11374283
56815599	56815622	5	-	28162770	EOL1	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	0.8857285226800062	[112]	[109]	7	hSpCas9	negative selection	11374284
56815879	56815902	5	+	28162770	EOL1	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-2.5176745570345394	[249]	[22]	-8	hSpCas9	negative selection	11374285
56815823	56815846	5	-	28162770	MOLM13	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-5.6406350752335905	[68]	[0]	-9	hSpCas9	negative selection	11543645
56864755	56864778	5	-	28162770	MOLM13	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-0.23512888069828963	[69]	[42]	-1	hSpCas9	negative selection	11543646
56882106	56882129	5	-	28162770	MOLM13	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.48203356386484847	[202]	[204]	3	hSpCas9	negative selection	11543647
56882803	56882826	5	-	28162770	MOLM13	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	-1.675804078324554	[326]	[73]	-7	hSpCas9	negative selection	11543648
56815561	56815584	5	+	28162770	MOLM13	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	1.1589802331270782	[261]	[422]	8	hSpCas9	negative selection	11543649
56815599	56815622	5	-	28162770	MOLM13	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	0.5141830338185138	[91]	[94]	4	hSpCas9	negative selection	11543650
56815879	56815902	5	+	28162770	MOLM13	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-1.2520026992626856	[223]	[67]	-6	hSpCas9	negative selection	11543651
56815823	56815846	5	-	28162770	HEL	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-0.7861044668035171	[34]	[12]	-5	hSpCas9	negative selection	11713011
56864755	56864778	5	-	28162770	HEL	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-2.067754550804658	[71]	[10]	-8	hSpCas9	negative selection	11713012
56882106	56882129	5	-	28162770	HEL	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.27465174764808287	[261]	[202]	2	hSpCas9	negative selection	11713013
56882803	56882826	5	-	28162770	HEL	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	0.4697924785828074	[238]	[211]	4	hSpCas9	negative selection	11713014
56815561	56815584	5	+	28162770	HEL	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	0.41487128059775796	[307]	[262]	3	hSpCas9	negative selection	11713015
56815599	56815622	5	-	28162770	HEL	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	1.6334610184123461	[77]	[154]	9	hSpCas9	negative selection	11713016
56815879	56815902	5	+	28162770	HEL	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-2.5731985671987916	[222]	[23]	-8	hSpCas9	negative selection	11713017
56815823	56815846	5	-	28162770	MV411	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-3.1101144538353083	[40]	[3]	-9	hSpCas9	negative selection	11882377
56864755	56864778	5	-	28162770	MV411	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-1.8031885222871926	[57]	[13]	-8	hSpCas9	negative selection	11882378
56882106	56882129	5	-	28162770	MV411	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.8324000515039315	[131]	[197]	7	hSpCas9	negative selection	11882379
56882803	56882826	5	-	28162770	MV411	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	0.40426456335617267	[208]	[232]	3	hSpCas9	negative selection	11882380
56815561	56815584	5	+	28162770	MV411	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	0.0567539891736655	[209]	[183]	0	hSpCas9	negative selection	11882381
56815599	56815622	5	-	28162770	MV411	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	-0.7742575203165438	[66]	[32]	-5	hSpCas9	negative selection	11882382
56815879	56815902	5	+	28162770	MV411	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-0.46584904691392026	[140]	[85]	-3	hSpCas9	negative selection	11882383
56815823	56815846	5	-	28162770	MONOMAC1	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-4.8974765652006464	[25]	[0]	-9	hSpCas9	negative selection	12051743
56864755	56864778	5	-	28162770	MONOMAC1	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-0.08600553467080996	[24]	[26]	0	hSpCas9	negative selection	12051744
56882106	56882129	5	-	28162770	MONOMAC1	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	-0.823993436445337	[121]	[78]	-6	hSpCas9	negative selection	12051745
56882803	56882826	5	-	28162770	MONOMAC1	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	-0.06294395147227055	[153]	[168]	0	hSpCas9	negative selection	12051746
56815561	56815584	5	+	28162770	MONOMAC1	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	0.11846497866837555	[134]	[167]	1	hSpCas9	negative selection	12051747
56815599	56815622	5	-	28162770	MONOMAC1	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	1.6231421153556338	[31]	[112]	9	hSpCas9	negative selection	12051748
56815879	56815902	5	+	28162770	MONOMAC1	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	0.23180645174432052	[103]	[139]	2	hSpCas9	negative selection	12051749
56815823	56815846	5	-	28162770	OCIAML2	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-3.8856673245210054	[7]	[2]	-9	hSpCas9	negative selection	12221109
56864755	56864778	5	-	28162770	OCIAML2	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-0.0971714297147166	[10]	[56]	-1	hSpCas9	negative selection	12221110
56882106	56882129	5	-	28162770	OCIAML2	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	-0.3816248191834164	[54]	[233]	-3	hSpCas9	negative selection	12221111
56882803	56882826	5	-	28162770	OCIAML2	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	-0.7073300832624926	[37]	[128]	-5	hSpCas9	negative selection	12221112
56815561	56815584	5	+	28162770	OCIAML2	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	0.7823509159277098	[29]	[285]	7	hSpCas9	negative selection	12221113
56815599	56815622	5	-	28162770	OCIAML2	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	-0.5500642927365664	[13]	[52]	-4	hSpCas9	negative selection	12221114
56815879	56815902	5	+	28162770	OCIAML2	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	0.06334874676019003	[23]	[138]	0	hSpCas9	negative selection	12221115
56815823	56815846	5	-	28162770	OCIAML3	viability	GGGGAAGTCGAGGAGGCCGGCGG	MAP3K1	ENSG00000095015	-5.594007640324163	[15]	[0]	-9	hSpCas9	negative selection	12390475
56864755	56864778	5	-	28162770	OCIAML3	viability	GGTGAAGGGGCTCTTCGGGGTGG	MAP3K1	ENSG00000095015	-0.14149543562665645	[18]	[51]	-1	hSpCas9	negative selection	12390476
56882106	56882129	5	-	28162770	OCIAML3	viability	GGAATGATGAGATAAAGGAGAGG	MAP3K1	ENSG00000095015	0.6103508581820231	[45]	[211]	5	hSpCas9	negative selection	12390477
56882803	56882826	5	-	28162770	OCIAML3	viability	GCAGCTGAGGAACTATGGGGAGG	MAP3K1	ENSG00000095015	0.8939304060021283	[40]	[229]	7	hSpCas9	negative selection	12390478
56815561	56815584	5	+	28162770	OCIAML3	viability	CCCGCGAGAGAAAATGGCGGCGG	MAP3K1	ENSG00000095015	-0.07527883800309373	[51]	[148]	0	hSpCas9	negative selection	12390479
56815599	56815622	5	-	28162770	OCIAML3	viability	GCCCGGGAATCCCGACGACGAGG	MAP3K1	ENSG00000095015	0.0998892319501572	[16]	[54]	0	hSpCas9	negative selection	12390480
56815879	56815902	5	+	28162770	OCIAML3	viability	GACCGGCTTCCAGCCTGTGGCGG	MAP3K1	ENSG00000095015	-0.5544792761375258	[53]	[110]	-4	hSpCas9	negative selection	12390481