Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4215
• Symbol:MAP3K3
• Description:mitogen-activated protein kinase kinase kinase 3

DataSource: http://genomecrispr.dkfz.de/#!/results/MAP3K3

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
63666947	63666970	17	-	26472758	Jiyoye	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	0.4787286425309074	[58]	[61]	3	hSpCas9	negative selection	96013
63690315	63690338	17	-	26472758	Jiyoye	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.0015365802292792163	[101]	[76]	0	hSpCas9	negative selection	96014
63681797	63681820	17	-	26472758	Jiyoye	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	0.02866375825214368	[116]	[89]	0	hSpCas9	negative selection	96015
63689592	63689615	17	-	26472758	Jiyoye	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-0.27795128114071455	[81]	[50]	-2	hSpCas9	negative selection	96016
63691792	63691815	17	+	26472758	Jiyoye	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	0.25256343555806526	[245]	[220]	2	hSpCas9	negative selection	96017
63692312	63692335	17	+	26472758	Jiyoye	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	0.31851776168547663	[301]	[283]	2	hSpCas9	negative selection	96018
63666984	63667007	17	+	26472758	Jiyoye	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	0.1978865474436058	[273]	[236]	1	hSpCas9	negative selection	96019
63681776	63681799	17	-	26472758	Jiyoye	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	0.4596428014000091	[53]	[55]	3	hSpCas9	negative selection	96020
63685548	63685571	17	-	26472758	Jiyoye	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.6306136129938725	[196]	[229]	4	hSpCas9	negative selection	96021
63688838	63688861	17	-	26472758	Jiyoye	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	-1.3090316524935353	[22]	[6]	-7	hSpCas9	negative selection	96022
63666947	63666970	17	-	26472758	KBM7	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-0.6621824567035078	[371,268]	[53,129]	-5	hSpCas9	negative selection	287131
63690315	63690338	17	-	26472758	KBM7	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.2510098022639835	[388,266]	[103,148]	-2	hSpCas9	negative selection	287132
63681797	63681820	17	-	26472758	KBM7	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	0.5424070667774941	[491,274]	[297,218]	6	hSpCas9	negative selection	287133
63689592	63689615	17	-	26472758	KBM7	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-1.2232623089397565	[438,187]	[72,49]	-7	hSpCas9	negative selection	287134
63691792	63691815	17	+	26472758	KBM7	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	0.1457032726627051	[1055,782]	[598,360]	1	hSpCas9	negative selection	287135
63692312	63692335	17	+	26472758	KBM7	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	0.16754603901871223	[1410,791]	[580,555]	1	hSpCas9	negative selection	287136
63666984	63667007	17	+	26472758	KBM7	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	0.1281602533806474	[944,637]	[331,461]	1	hSpCas9	negative selection	287137
63681776	63681799	17	-	26472758	KBM7	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	0.31606206792171265	[182,194]	[110,111]	3	hSpCas9	negative selection	287138
63685548	63685571	17	-	26472758	KBM7	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.2919485789160612	[1063,902]	[579,549]	3	hSpCas9	negative selection	287139
63688838	63688861	17	-	26472758	KBM7	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	-0.19388011633664304	[46,67]	[29,18]	-2	hSpCas9	negative selection	287140
63666947	63666970	17	-	26472758	Raji	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-1.4104647694890193	[251]	[21]	-7	hSpCas9	negative selection	478249
63690315	63690338	17	-	26472758	Raji	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.19392028584159487	[274]	[72]	1	hSpCas9	negative selection	478250
63681797	63681820	17	-	26472758	Raji	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	0.9218278822175228	[115]	[50]	8	hSpCas9	negative selection	478251
63689592	63689615	17	-	26472758	Raji	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-1.1921767464853081	[127]	[12]	-7	hSpCas9	negative selection	478252
63691792	63691815	17	+	26472758	Raji	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	-0.7356834834034076	[408]	[56]	-5	hSpCas9	negative selection	478253
63692312	63692335	17	+	26472758	Raji	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	0.18591693792028896	[571]	[150]	1	hSpCas9	negative selection	478254
63666984	63667007	17	+	26472758	Raji	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.38575138693190536	[562]	[99]	-3	hSpCas9	negative selection	478255
63681776	63681799	17	-	26472758	Raji	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	-1.1336245641301954	[103]	[10]	-7	hSpCas9	negative selection	478256
63685548	63685571	17	-	26472758	Raji	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.06460951168330797	[444]	[107]	0	hSpCas9	negative selection	478257
63688838	63688861	17	-	26472758	Raji	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	-3.102069830255351	[36]	[0]	-9	hSpCas9	negative selection	478258
63666947	63666970	17	-	26472758	K562	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-5.340543773054709	[287]	[5]	-9	hSpCas9	negative selection	669367
63690315	63690338	17	-	26472758	K562	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.8994287259158597	[267]	[421]	7	hSpCas9	negative selection	669368
63681797	63681820	17	-	26472758	K562	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-0.05865033996959956	[284]	[230]	0	hSpCas9	negative selection	669369
63689592	63689615	17	-	26472758	K562	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-4.141012309527073	[208]	[9]	-9	hSpCas9	negative selection	669370
63691792	63691815	17	+	26472758	K562	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	0.39296102710587233	[792]	[878]	3	hSpCas9	negative selection	669371
63692312	63692335	17	+	26472758	K562	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	0.5223140544911431	[997]	[1209]	4	hSpCas9	negative selection	669372
63666984	63667007	17	+	26472758	K562	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.46691455447002084	[780]	[476]	-3	hSpCas9	negative selection	669373
63681776	63681799	17	-	26472758	K562	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	-1.0049407412702704	[125]	[52]	-5	hSpCas9	negative selection	669374
63685548	63685571	17	-	26472758	K562	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.08515808008310777	[774]	[693]	0	hSpCas9	negative selection	669375
63688838	63688861	17	-	26472758	K562	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	-0.09661819016861983	[18]	[14]	0	hSpCas9	negative selection	669376
63622758	63622781	17	-	26627737	DLD1	viability	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	1.2777243950758277	[16]	[12,8,15]	9	hSpCas9	negative selection	799273
63632667	63632690	17	+	26627737	DLD1	viability	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.442887284680864	[1637]	[650,788,657]	4	hSpCas9	negative selection	799274
63646045	63646068	17	+	26627737	DLD1	viability	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.09800700338544832	[978]	[358,380,255]	1	hSpCas9	negative selection	799275
63666983	63667006	17	+	26627737	DLD1	viability	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	0.505742834885805	[550]	[141,296,289]	5	hSpCas9	negative selection	799276
63681796	63681819	17	-	26627737	DLD1	viability	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.37726623776296575	[962]	[277,141,265]	-4	hSpCas9	negative selection	799277
63685557	63685580	17	+	26627737	DLD1	viability	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.760560230046099	[361]	[118,58,27]	-6	hSpCas9	negative selection	799278
63622758	63622781	17	-	26627737	GBM cells	viability after 5 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	0.8989138748856851	[1]	[0,2]	9	hSpCas9	negative selection	881588
63632667	63632690	17	+	26627737	GBM cells	viability after 5 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.44133068064075687	[779]	[524,610]	6	hSpCas9	negative selection	881589
63646045	63646068	17	+	26627737	GBM cells	viability after 5 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.04882458936949541	[620]	[345,342]	0	hSpCas9	negative selection	881590
63666983	63667006	17	+	26627737	GBM cells	viability after 5 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	0.08359264301802481	[226]	[88,168]	1	hSpCas9	negative selection	881591
63681796	63681819	17	-	26627737	GBM cells	viability after 5 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.47989524193356664	[484]	[174,197]	-6	hSpCas9	negative selection	881592
63685557	63685580	17	+	26627737	GBM cells	viability after 5 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.30510001713590795	[181]	[55,101]	-5	hSpCas9	negative selection	881593
63622758	63622781	17	-	26627737	GBM cells	viability after 13 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	0.41669210178448424	[1]	[1,0]	5	hSpCas9	negative selection	963903
63632667	63632690	17	+	26627737	GBM cells	viability after 13 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.496128916496557	[779]	[613,582]	6	hSpCas9	negative selection	963904
63646045	63646068	17	+	26627737	GBM cells	viability after 13 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.25539128634890385	[620]	[442,368]	3	hSpCas9	negative selection	963905
63666983	63667006	17	+	26627737	GBM cells	viability after 13 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	0.06035341988111499	[226]	[155,105]	0	hSpCas9	negative selection	963906
63681796	63681819	17	-	26627737	GBM cells	viability after 13 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.5393059652168166	[484]	[190,172]	-6	hSpCas9	negative selection	963907
63685557	63685580	17	+	26627737	GBM cells	viability after 13 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.9074104857189692	[181]	[34,66]	-8	hSpCas9	negative selection	963908
63622758	63622781	17	-	26627737	GBM cells	viability after 21 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	0.4864122862465097	[1]	[0,1]	5	hSpCas9	negative selection	1046218
63632667	63632690	17	+	26627737	GBM cells	viability after 21 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.8168799623713903	[779]	[828,670]	7	hSpCas9	negative selection	1046219
63646045	63646068	17	+	26627737	GBM cells	viability after 21 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.25263614137195156	[620]	[414,389]	2	hSpCas9	negative selection	1046220
63666983	63667006	17	+	26627737	GBM cells	viability after 21 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.43781610652462993	[226]	[89,91]	-4	hSpCas9	negative selection	1046221
63681796	63681819	17	-	26627737	GBM cells	viability after 21 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-1.1040539922745256	[484]	[108,134]	-7	hSpCas9	negative selection	1046222
63685557	63685580	17	+	26627737	GBM cells	viability after 21 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.6622901053719085	[181]	[62,61]	-5	hSpCas9	negative selection	1046223
63622758	63622781	17	-	26627737	RPE1	viability after 9 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	1.0068261005467543	[14]	[8,9]	6	hSpCas9	negative selection	1128533
63632667	63632690	17	+	26627737	RPE1	viability after 9 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.34392301823629445	[3867]	[1353,1772]	2	hSpCas9	negative selection	1128534
63646045	63646068	17	+	26627737	RPE1	viability after 9 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.9382719786161644	[777]	[333,637]	6	hSpCas9	negative selection	1128535
63666983	63667006	17	+	26627737	RPE1	viability after 9 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	1.6073708410741678	[300]	[256,325]	8	hSpCas9	negative selection	1128536
63681796	63681819	17	-	26627737	RPE1	viability after 9 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.6639927666281775	[2021]	[347,465]	-5	hSpCas9	negative selection	1128537
63685557	63685580	17	+	26627737	RPE1	viability after 9 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-1.234019593459991	[457]	[70,47]	-7	hSpCas9	negative selection	1128538
63622758	63622781	17	-	26627737	RPE1	viability after 12 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	0.8024523044588925	[14]	[7,5]	5	hSpCas9	negative selection	1210848
63632667	63632690	17	+	26627737	RPE1	viability after 12 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.2907146466574533	[3867]	[1260,1281]	2	hSpCas9	negative selection	1210849
63646045	63646068	17	+	26627737	RPE1	viability after 12 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	1.1569365508339071	[777]	[366,570]	7	hSpCas9	negative selection	1210850
63666983	63667006	17	+	26627737	RPE1	viability after 12 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	1.535847955927924	[300]	[182,288]	8	hSpCas9	negative selection	1210851
63681796	63681819	17	-	26627737	RPE1	viability after 12 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-1.9218421317656704	[2021]	[138,147]	-8	hSpCas9	negative selection	1210852
63685557	63685580	17	+	26627737	RPE1	viability after 12 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.641400220780703	[457]	[91,64]	-4	hSpCas9	negative selection	1210853
63622758	63622781	17	-	26627737	RPE1	viability after 15 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-0.4915013299434703	[14]	[1,3]	-3	hSpCas9	negative selection	1293163
63632667	63632690	17	+	26627737	RPE1	viability after 15 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.3348506329639509	[3867]	[1631,1136]	2	hSpCas9	negative selection	1293164
63646045	63646068	17	+	26627737	RPE1	viability after 15 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	1.0325708757436023	[777]	[325,569]	6	hSpCas9	negative selection	1293165
63666983	63667006	17	+	26627737	RPE1	viability after 15 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	1.5521106189771339	[300]	[210,286]	8	hSpCas9	negative selection	1293166
63681796	63681819	17	-	26627737	RPE1	viability after 15 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-2.169643837887193	[2021]	[175,79]	-8	hSpCas9	negative selection	1293167
63685557	63685580	17	+	26627737	RPE1	viability after 15 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.5261459231407035	[457]	[119,60]	-3	hSpCas9	negative selection	1293168
63622758	63622781	17	-	26627737	RPE1	viability after 18 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	0.411425595289721	[14]	[1,8]	2	hSpCas9	negative selection	1375478
63632667	63632690	17	+	26627737	RPE1	viability after 18 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.34545512692757274	[3867]	[1304,1348]	2	hSpCas9	negative selection	1375479
63646045	63646068	17	+	26627737	RPE1	viability after 18 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	1.3244538585220693	[777]	[330,733]	7	hSpCas9	negative selection	1375480
63666983	63667006	17	+	26627737	RPE1	viability after 18 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	1.5067316595284619	[300]	[254,204]	7	hSpCas9	negative selection	1375481
63681796	63681819	17	-	26627737	RPE1	viability after 18 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-1.9596886551057828	[2021]	[133,146]	-8	hSpCas9	negative selection	1375482
63685557	63685580	17	+	26627737	RPE1	viability after 18 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.41789537758880013	[457]	[92,91]	-3	hSpCas9	negative selection	1375483
63622758	63622781	17	-	26627737	HeLa	viability after 8 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-0.37613596579338116	[1085]	[402,231,458]	-4	hSpCas9	negative selection	1457793
63632667	63632690	17	+	26627737	HeLa	viability after 8 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.22650318108014544	[921]	[643,501,311]	2	hSpCas9	negative selection	1457794
63646045	63646068	17	+	26627737	HeLa	viability after 8 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.3728769473051401	[799]	[394,77,354]	-4	hSpCas9	negative selection	1457795
63666983	63667006	17	+	26627737	HeLa	viability after 8 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.5333632408782604	[635]	[254,160,172]	-5	hSpCas9	negative selection	1457796
63681796	63681819	17	-	26627737	HeLa	viability after 8 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.9829481708996306	[909]	[102,222,249]	-7	hSpCas9	negative selection	1457797
63685557	63685580	17	+	26627737	HeLa	viability after 8 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.24393458816352825	[294]	[185,117,42]	-2	hSpCas9	negative selection	1457798
63622758	63622781	17	-	26627737	HeLa	viability after 12 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-0.729344104024645	[1085]	[310,282,217]	-6	hSpCas9	negative selection	1540108
63632667	63632690	17	+	26627737	HeLa	viability after 12 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.7895151652555863	[921]	[741,509,741]	6	hSpCas9	negative selection	1540109
63646045	63646068	17	+	26627737	HeLa	viability after 12 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.7500469545398174	[799]	[205,139,249]	-6	hSpCas9	negative selection	1540110
63666983	63667006	17	+	26627737	HeLa	viability after 12 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-1.0455340675539986	[635]	[152,124,104]	-7	hSpCas9	negative selection	1540111
63681796	63681819	17	-	26627737	HeLa	viability after 12 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.6747366034730621	[909]	[294,126,297]	-6	hSpCas9	negative selection	1540112
63685557	63685580	17	+	26627737	HeLa	viability after 12 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	0.1703640981024465	[294]	[202,122,88]	1	hSpCas9	negative selection	1540113
63622758	63622781	17	-	26627737	HeLa	viability after 15 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-1.143472205463803	[1085]	[331,86,177]	-7	hSpCas9	negative selection	1622423
63632667	63632690	17	+	26627737	HeLa	viability after 15 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.2947457187511404	[921]	[357,329,713]	2	hSpCas9	negative selection	1622424
63646045	63646068	17	+	26627737	HeLa	viability after 15 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.6300069870146938	[799]	[216,218,193]	-5	hSpCas9	negative selection	1622425
63666983	63667006	17	+	26627737	HeLa	viability after 15 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.6382831357251665	[635]	[217,178,95]	-5	hSpCas9	negative selection	1622426
63681796	63681819	17	-	26627737	HeLa	viability after 15 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.758102904179832	[909]	[418,143,80]	-6	hSpCas9	negative selection	1622427
63685557	63685580	17	+	26627737	HeLa	viability after 15 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.7148841164608597	[294]	[42,29,152]	-6	hSpCas9	negative selection	1622428
63622758	63622781	17	-	26627737	HeLa	viability after 18 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-1.1635941432846004	[1085]	[214,74,177]	-8	hSpCas9	negative selection	1704738
63632667	63632690	17	+	26627737	HeLa	viability after 18 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.31521055598431524	[921]	[245,281,713]	2	hSpCas9	negative selection	1704739
63646045	63646068	17	+	26627737	HeLa	viability after 18 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.6092578323991937	[799]	[150,181,193]	-5	hSpCas9	negative selection	1704740
63666983	63667006	17	+	26627737	HeLa	viability after 18 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.5980277653865699	[635]	[153,149,95]	-5	hSpCas9	negative selection	1704741
63681796	63681819	17	-	26627737	HeLa	viability after 18 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.7105566428423085	[909]	[297,115,80]	-6	hSpCas9	negative selection	1704742
63685557	63685580	17	+	26627737	HeLa	viability after 18 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.7635848838403401	[294]	[23,24,152]	-6	hSpCas9	negative selection	1704743
63622758	63622781	17	-	26627737	HCT116	viability after 6 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-6.902497637798082	[1301]	[2,0]	-9	hSpCas9	negative selection	1787053
63632667	63632690	17	+	26627737	HCT116	viability after 6 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.8059415872019311	[1488]	[561,324]	4	hSpCas9	negative selection	1787054
63646045	63646068	17	+	26627737	HCT116	viability after 6 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-2.4664167541844444	[1045]	[41,22]	-8	hSpCas9	negative selection	1787055
63666983	63667006	17	+	26627737	HCT116	viability after 6 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	0.3793173031671696	[403]	[148,45]	2	hSpCas9	negative selection	1787056
63681796	63681819	17	-	26627737	HCT116	viability after 6 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.7350289424914336	[1185]	[267,25]	-4	hSpCas9	negative selection	1787057
63685557	63685580	17	+	26627737	HCT116	viability after 6 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.1815091435966284	[352]	[46,49]	-1	hSpCas9	negative selection	1787058
63622758	63622781	17	-	26627737	HCT116	viability after 8 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-1.4596262175458963	[733]	[128,177,133]	-9	hSpCas9	negative selection	1869368
63632667	63632690	17	+	26627737	HCT116	viability after 8 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.21741209510887538	[728]	[578,513,311]	2	hSpCas9	negative selection	1869369
63646045	63646068	17	+	26627737	HCT116	viability after 8 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.11771006439325882	[394]	[340,186,182]	1	hSpCas9	negative selection	1869370
63666983	63667006	17	+	26627737	HCT116	viability after 8 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	0.09054772357438806	[398]	[190,314,195]	1	hSpCas9	negative selection	1869371
63681796	63681819	17	-	26627737	HCT116	viability after 8 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.7146378035151071	[660]	[259,141,263]	-7	hSpCas9	negative selection	1869372
63685557	63685580	17	+	26627737	HCT116	viability after 8 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.277845968413036	[187]	[34,98,120]	-3	hSpCas9	negative selection	1869373
63622758	63622781	17	-	26627737	HCT116	viability after 9 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-4.509721628830074	[1301]	[7,20]	-9	hSpCas9	negative selection	1951683
63632667	63632690	17	+	26627737	HCT116	viability after 9 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.6586958492625861	[1488]	[773,511]	5	hSpCas9	negative selection	1951684
63646045	63646068	17	+	26627737	HCT116	viability after 9 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.5563006421964124	[1045]	[242,147]	-4	hSpCas9	negative selection	1951685
63666983	63667006	17	+	26627737	HCT116	viability after 9 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	0.4600905768838221	[403]	[301,26]	3	hSpCas9	negative selection	1951686
63681796	63681819	17	-	26627737	HCT116	viability after 9 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	0.2784701245097374	[1185]	[239,497]	2	hSpCas9	negative selection	1951687
63685557	63685580	17	+	26627737	HCT116	viability after 9 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.5082446638558799	[352]	[15,105]	-4	hSpCas9	negative selection	1951688
63622758	63622781	17	-	26627737	HCT116	viability after 12 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-1.8458608191247259	[733]	[97,117,106]	-9	hSpCas9	negative selection	2033998
63632667	63632690	17	+	26627737	HCT116	viability after 12 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.7987447502187519	[728]	[606,683,713]	7	hSpCas9	negative selection	2033999
63646045	63646068	17	+	26627737	HCT116	viability after 12 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.05748948927609171	[394]	[284,161,142]	0	hSpCas9	negative selection	2034000
63666983	63667006	17	+	26627737	HCT116	viability after 12 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.2144235511401684	[398]	[144,208,191]	-2	hSpCas9	negative selection	2034001
63681796	63681819	17	-	26627737	HCT116	viability after 12 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.9454858751325185	[660]	[97,82,364]	-7	hSpCas9	negative selection	2034002
63685557	63685580	17	+	26627737	HCT116	viability after 12 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.810930560713771	[187]	[35,25,107]	-7	hSpCas9	negative selection	2034003
63622758	63622781	17	-	26627737	HCT116	viability after 15 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-2.4396807288270494	[733]	[152,72,16]	-9	hSpCas9	negative selection	2116313
63632667	63632690	17	+	26627737	HCT116	viability after 15 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.634581875173758	[728]	[408,730,778]	6	hSpCas9	negative selection	2116314
63646045	63646068	17	+	26627737	HCT116	viability after 15 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.47495191091997624	[394]	[195,164,132]	-5	hSpCas9	negative selection	2116315
63666983	63667006	17	+	26627737	HCT116	viability after 15 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.3013228204158455	[398]	[260,120,184]	-3	hSpCas9	negative selection	2116316
63681796	63681819	17	-	26627737	HCT116	viability after 15 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-1.029774175432075	[660]	[175,146,232]	-8	hSpCas9	negative selection	2116317
63685557	63685580	17	+	26627737	HCT116	viability after 15 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.4328641348742984	[187]	[104,58,78]	-4	hSpCas9	negative selection	2116318
63622758	63622781	17	-	26627737	HCT116	viability after 18 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-1.581359216885036	[733]	[106,103,146]	-8	hSpCas9	negative selection	2198628
63632667	63632690	17	+	26627737	HCT116	viability after 18 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.5710625039413944	[728]	[368,447,769]	5	hSpCas9	negative selection	2198629
63646045	63646068	17	+	26627737	HCT116	viability after 18 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.489313937333734	[394]	[201,126,76]	-4	hSpCas9	negative selection	2198630
63666983	63667006	17	+	26627737	HCT116	viability after 18 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.543133699703898	[398]	[123,196,68]	-5	hSpCas9	negative selection	2198631
63681796	63681819	17	-	26627737	HCT116	viability after 18 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.817784504554232	[660]	[107,98,349]	-6	hSpCas9	negative selection	2198632
63685557	63685580	17	+	26627737	HCT116	viability after 18 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-1.6159438023730899	[187]	[28,20,39]	-8	hSpCas9	negative selection	2198633
63632667	63632690	17	+	24336569	HL60	viability	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.5963106785346138	[606]	[1941]	5	hSpCas9	negative selection	2275908
63632697	63632720	17	+	24336569	HL60	viability	GAACTCAATCATGAACGATCTGG	MAP3K3	ENSG00000198909	0.009460083431659161	[1052]	[2242]	0	hSpCas9	negative selection	2275909
63632723	63632746	17	-	24336569	HL60	viability	GTGACGTCGGTTCATCTGGAGGG	MAP3K3	ENSG00000198909	0.1964346721742023	[691]	[1677]	2	hSpCas9	negative selection	2275910
63632734	63632757	17	+	24336569	HL60	viability	AACCGACGTCACCGGATGCCTGG	MAP3K3	ENSG00000198909	-0.7803695091586995	[1115]	[1374]	-6	hSpCas9	negative selection	2275911
63632745	63632768	17	-	24336569	HL60	viability	TGGTCTCATATCCAGGCATCCGG	MAP3K3	ENSG00000198909	0.8159230222911804	[527]	[1966]	6	hSpCas9	negative selection	2275912
63632752	63632775	17	-	24336569	HL60	viability	TTCTTCATGGTCTCATATCCAGG	MAP3K3	ENSG00000198909	0.394706428534787	[926]	[2578]	3	hSpCas9	negative selection	2275913
63632764	63632787	17	+	24336569	HL60	viability	ACCATGAAGAACAAAGACACAGG	MAP3K3	ENSG00000198909	-1.1586034986104745	[556]	[527]	-8	hSpCas9	negative selection	2275914
63632777	63632800	17	+	24336569	HL60	viability	AAGACACAGGTCACTCAAATAGG	MAP3K3	ENSG00000198909	0.41111364596934363	[574]	[1617]	4	hSpCas9	negative selection	2275915
63646043	63646066	17	+	24336569	HL60	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.10046109108626244	[1719]	[3394]	-1	hSpCas9	negative selection	2275916
63652553	63652576	17	+	24336569	HL60	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.08157791396719877	[676]	[1515]	0	hSpCas9	negative selection	2275917
63632667	63632690	17	+	24336569	KBM7	viability	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.35596187239383936	[486]	[1699]	3	hSpCas9	negative selection	2343085
63632697	63632720	17	+	24336569	KBM7	viability	GAACTCAATCATGAACGATCTGG	MAP3K3	ENSG00000198909	0.276606984368857	[634]	[2097]	2	hSpCas9	negative selection	2343086
63632723	63632746	17	-	24336569	KBM7	viability	GTGACGTCGGTTCATCTGGAGGG	MAP3K3	ENSG00000198909	-1.3620752083366	[736]	[781]	-7	hSpCas9	negative selection	2343087
63632734	63632757	17	+	24336569	KBM7	viability	AACCGACGTCACCGGATGCCTGG	MAP3K3	ENSG00000198909	0.056607802257792716	[703]	[1996]	0	hSpCas9	negative selection	2343088
63632745	63632768	17	-	24336569	KBM7	viability	TGGTCTCATATCCAGGCATCCGG	MAP3K3	ENSG00000198909	0.47233947979205443	[462]	[1751]	4	hSpCas9	negative selection	2343089
63632752	63632775	17	-	24336569	KBM7	viability	TTCTTCATGGTCTCATATCCAGG	MAP3K3	ENSG00000198909	1.129291891818726	[446]	[2666]	8	hSpCas9	negative selection	2343090
63632764	63632787	17	+	24336569	KBM7	viability	ACCATGAAGAACAAAGACACAGG	MAP3K3	ENSG00000198909	-0.3513638812895793	[405]	[867]	-3	hSpCas9	negative selection	2343091
63632777	63632800	17	+	24336569	KBM7	viability	AAGACACAGGTCACTCAAATAGG	MAP3K3	ENSG00000198909	0.715968235122713	[528]	[2369]	6	hSpCas9	negative selection	2343092
63646043	63646066	17	+	24336569	KBM7	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.16770246033823222	[1286]	[3942]	1	hSpCas9	negative selection	2343093
63652553	63652576	17	+	24336569	KBM7	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.3925899619512301	[295]	[614]	-3	hSpCas9	negative selection	2343094
63656185	63656208	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCCACTGCACTCCAGCCTGGG	MAP3K3	ENSG00000198909	-0.4511660430985071	[55,91]	[10,11]	-2	dCas9-VP64	positive selection	2390526
63659617	63659640	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATTGCTTGAACCCGGGAGGTGG	MAP3K3	ENSG00000198909	0.3272337489211984	[8,246]	[5,67]	1	dCas9-VP64	positive selection	2421320
63660630	63660653	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCCCAGGCTGGAGTGCAGGGG	MAP3K3	ENSG00000198909	0.9977856233970179	[9,4]	[4,0]	4	dCas9-VP64	positive selection	2435931
63683910	63683933	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTTTGGGAGGCCAAGGCAGGAG	MAP3K3	ENSG00000198909	2.0119762381202047	[93,200]	[9,263]	7	dCas9-VP64	positive selection	2462398
63656185	63656208	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCCACTGCACTCCAGCCTGGG	MAP3K3	ENSG00000198909	-0.10831419915270625	[89,129]	[31,33]	-1	dCas9-VP64	positive selection	2485781
63659617	63659640	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATTGCTTGAACCCGGGAGGTGG	MAP3K3	ENSG00000198909	0.646844560450541	[111,36]	[52,24]	5	dCas9-VP64	positive selection	2516575
63660630	63660653	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCCCAGGCTGGAGTGCAGGGG	MAP3K3	ENSG00000198909	-0.1814090993543942	[50,40]	[18,6]	-2	dCas9-VP64	positive selection	2531186
63683910	63683933	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTTTGGGAGGCCAAGGCAGGAG	MAP3K3	ENSG00000198909	-0.4547686614086857	[146,265]	[55,41]	-5	dCas9-VP64	positive selection	2557653
63632734	63632757	17	+	27260157	DLD1	viability	AACCGACGTCACCGGATGCCTGG	MAP3K3	ENSG00000198909	1.11876119021556	[]	[]	9	hSpCas9	negative selection	2574693
63632752	63632775	17	-	27260157	DLD1	viability	TTCTTCATGGTCTCATATCCAGG	MAP3K3	ENSG00000198909	0.455551990792751	[]	[]	7	hSpCas9	negative selection	2574713
63681769	63681792	17	-	27260157	DLD1	viability	TGAGCTTCGGCCAGGGTTCTGGG	MAP3K3	ENSG00000198909	0.80841165958082	[]	[]	9	hSpCas9	negative selection	2574782
63632700	63632723	17	+	27260157	DLD1	viability	CTCAATCATGAACGATCTGGTGG	MAP3K3	ENSG00000198909	0.527025254752675	[]	[]	8	hSpCas9	negative selection	2575435
63632736	63632759	17	-	27260157	DLD1	viability	ATCCAGGCATCCGGTGACGTCGG	MAP3K3	ENSG00000198909	0.511505446186829	[]	[]	8	hSpCas9	negative selection	2577570
63666968	63666991	17	-	27260157	DLD1	viability	AGCCTTGATCCGCACCTGTCTGG	MAP3K3	ENSG00000198909	-0.181875225896574	[]	[]	-1	hSpCas9	negative selection	2578809
63622743	63622766	17	-	27260157	DLD1	viability	ACCCATGGTGGCGATGGCGGCGG	MAP3K3	ENSG00000198909	-1.16826819977737	[]	[]	-7	hSpCas9	negative selection	2584933
63685564	63685587	17	-	27260157	DLD1	viability	CTGCTGACCTGTCCAAGGATTGG	MAP3K3	ENSG00000198909	0.624715010396637	[]	[]	8	hSpCas9	negative selection	2606134
63622755	63622778	17	-	27260157	DLD1	viability	GTGGCGACACTTACCCATGGTGG	MAP3K3	ENSG00000198909	-0.0632278157321741	[]	[]	0	hSpCas9	negative selection	2607236
63666966	63666989	17	+	27260157	DLD1	viability	GTCCAGACAGGTGCGGATCAAGG	MAP3K3	ENSG00000198909	0.483239498014494	[]	[]	8	hSpCas9	negative selection	2609566
63646043	63646066	17	+	27260157	DLD1	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.910959871260482	[]	[]	9	hSpCas9	negative selection	2609620
63632764	63632787	17	+	27260157	DLD1	viability	ACCATGAAGAACAAAGACACAGG	MAP3K3	ENSG00000198909	0.283997411867738	[]	[]	4	hSpCas9	negative selection	2611738
63632667	63632690	17	+	27260157	DLD1	viability	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.577880863098067	[]	[]	8	hSpCas9	negative selection	2614079
63646044	63646067	17	+	27260157	DLD1	viability	GAATCAAGTTCGAGCACAACGGG	MAP3K3	ENSG00000198909	0.612269338826448	[]	[]	8	hSpCas9	negative selection	2616054
63632745	63632768	17	-	27260157	DLD1	viability	TGGTCTCATATCCAGGCATCCGG	MAP3K3	ENSG00000198909	0.121028352902318	[]	[]	3	hSpCas9	negative selection	2617474
63632697	63632720	17	+	27260157	DLD1	viability	GAACTCAATCATGAACGATCTGG	MAP3K3	ENSG00000198909	-1.53434035589429	[]	[]	-8	hSpCas9	negative selection	2619223
63652553	63652576	17	+	27260157	DLD1	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.0480156258627776	[]	[]	0	hSpCas9	negative selection	2642087
63632734	63632757	17	+	27260157	HT1080	viability	AACCGACGTCACCGGATGCCTGG	MAP3K3	ENSG00000198909	1.58634657925881	[]	[]	9	hSpCas9	negative selection	2650823
63632752	63632775	17	-	27260157	HT1080	viability	TTCTTCATGGTCTCATATCCAGG	MAP3K3	ENSG00000198909	-0.407630471288445	[]	[]	-7	hSpCas9	negative selection	2650843
63681769	63681792	17	-	27260157	HT1080	viability	TGAGCTTCGGCCAGGGTTCTGGG	MAP3K3	ENSG00000198909	0.692324495569688	[]	[]	6	hSpCas9	negative selection	2650912
63632700	63632723	17	+	27260157	HT1080	viability	CTCAATCATGAACGATCTGGTGG	MAP3K3	ENSG00000198909	-0.0728494759711687	[]	[]	0	hSpCas9	negative selection	2651565
63632736	63632759	17	-	27260157	HT1080	viability	ATCCAGGCATCCGGTGACGTCGG	MAP3K3	ENSG00000198909	0.49038629768411	[]	[]	4	hSpCas9	negative selection	2653700
63666968	63666991	17	-	27260157	HT1080	viability	AGCCTTGATCCGCACCTGTCTGG	MAP3K3	ENSG00000198909	1.08692437982233	[]	[]	8	hSpCas9	negative selection	2654939
63622743	63622766	17	-	27260157	HT1080	viability	ACCCATGGTGGCGATGGCGGCGG	MAP3K3	ENSG00000198909	-1.36422719460461	[]	[]	-9	hSpCas9	negative selection	2661063
63685564	63685587	17	-	27260157	HT1080	viability	CTGCTGACCTGTCCAAGGATTGG	MAP3K3	ENSG00000198909	0.403710770054307	[]	[]	3	hSpCas9	negative selection	2682264
63622755	63622778	17	-	27260157	HT1080	viability	GTGGCGACACTTACCCATGGTGG	MAP3K3	ENSG00000198909	-0.410579261665015	[]	[]	-7	hSpCas9	negative selection	2683366
63666966	63666989	17	+	27260157	HT1080	viability	GTCCAGACAGGTGCGGATCAAGG	MAP3K3	ENSG00000198909	0.269906325518381	[]	[]	2	hSpCas9	negative selection	2685696
63646043	63646066	17	+	27260157	HT1080	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	1.06491761538369	[]	[]	8	hSpCas9	negative selection	2685750
63632764	63632787	17	+	27260157	HT1080	viability	ACCATGAAGAACAAAGACACAGG	MAP3K3	ENSG00000198909	0.703804464279106	[]	[]	6	hSpCas9	negative selection	2687868
63632667	63632690	17	+	27260157	HT1080	viability	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.236980893611593	[]	[]	2	hSpCas9	negative selection	2690209
63646044	63646067	17	+	27260157	HT1080	viability	GAATCAAGTTCGAGCACAACGGG	MAP3K3	ENSG00000198909	1.05541965348824	[]	[]	8	hSpCas9	negative selection	2692184
63632745	63632768	17	-	27260157	HT1080	viability	TGGTCTCATATCCAGGCATCCGG	MAP3K3	ENSG00000198909	0.0254653691999726	[]	[]	0	hSpCas9	negative selection	2693604
63632697	63632720	17	+	27260157	HT1080	viability	GAACTCAATCATGAACGATCTGG	MAP3K3	ENSG00000198909	-0.804288128247572	[]	[]	-8	hSpCas9	negative selection	2695353
63652553	63652576	17	+	27260157	HT1080	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.32773107548479	[]	[]	-7	hSpCas9	negative selection	2718217
63632734	63632757	17	+	27260157	MKN45	viability	AACCGACGTCACCGGATGCCTGG	MAP3K3	ENSG00000198909	2.24335720737956	[]	[]	9	hSpCas9	negative selection	2726953
63632752	63632775	17	-	27260157	MKN45	viability	TTCTTCATGGTCTCATATCCAGG	MAP3K3	ENSG00000198909	-1.6589912786271	[]	[]	-9	hSpCas9	negative selection	2726973
63681769	63681792	17	-	27260157	MKN45	viability	TGAGCTTCGGCCAGGGTTCTGGG	MAP3K3	ENSG00000198909	-0.114750794750582	[]	[]	0	hSpCas9	negative selection	2727042
63632700	63632723	17	+	27260157	MKN45	viability	CTCAATCATGAACGATCTGGTGG	MAP3K3	ENSG00000198909	0.526112945244659	[]	[]	6	hSpCas9	negative selection	2727695
63632736	63632759	17	-	27260157	MKN45	viability	ATCCAGGCATCCGGTGACGTCGG	MAP3K3	ENSG00000198909	-0.214684733821995	[]	[]	-1	hSpCas9	negative selection	2729830
63666968	63666991	17	-	27260157	MKN45	viability	AGCCTTGATCCGCACCTGTCTGG	MAP3K3	ENSG00000198909	-0.783186370025711	[]	[]	-7	hSpCas9	negative selection	2731069
63622743	63622766	17	-	27260157	MKN45	viability	ACCCATGGTGGCGATGGCGGCGG	MAP3K3	ENSG00000198909	-0.832375895264695	[]	[]	-7	hSpCas9	negative selection	2737193
63685564	63685587	17	-	27260157	MKN45	viability	CTGCTGACCTGTCCAAGGATTGG	MAP3K3	ENSG00000198909	1.19136098073592	[]	[]	9	hSpCas9	negative selection	2758394
63622755	63622778	17	-	27260157	MKN45	viability	GTGGCGACACTTACCCATGGTGG	MAP3K3	ENSG00000198909	-1.65240995272574	[]	[]	-9	hSpCas9	negative selection	2759496
63666966	63666989	17	+	27260157	MKN45	viability	GTCCAGACAGGTGCGGATCAAGG	MAP3K3	ENSG00000198909	0.663365897706415	[]	[]	7	hSpCas9	negative selection	2761826
63646043	63646066	17	+	27260157	MKN45	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.189606253213837	[]	[]	5	hSpCas9	negative selection	2761880
63632764	63632787	17	+	27260157	MKN45	viability	ACCATGAAGAACAAAGACACAGG	MAP3K3	ENSG00000198909	0.380749333555419	[]	[]	6	hSpCas9	negative selection	2763998
63632667	63632690	17	+	27260157	MKN45	viability	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	1.27131436640103	[]	[]	9	hSpCas9	negative selection	2766339
63646044	63646067	17	+	27260157	MKN45	viability	GAATCAAGTTCGAGCACAACGGG	MAP3K3	ENSG00000198909	0.925452052130146	[]	[]	8	hSpCas9	negative selection	2768314
63632745	63632768	17	-	27260157	MKN45	viability	TGGTCTCATATCCAGGCATCCGG	MAP3K3	ENSG00000198909	-1.23936033297753	[]	[]	-8	hSpCas9	negative selection	2769734
63632697	63632720	17	+	27260157	MKN45	viability	GAACTCAATCATGAACGATCTGG	MAP3K3	ENSG00000198909	-0.339512871991399	[]	[]	-1	hSpCas9	negative selection	2771483
63652553	63652576	17	+	27260157	MKN45	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.0796481947621466	[]	[]	0	hSpCas9	negative selection	2794347
63632734	63632757	17	+	27260157	RKO	viability	AACCGACGTCACCGGATGCCTGG	MAP3K3	ENSG00000198909	2.3401109585749	[]	[]	9	hSpCas9	negative selection	2803083
63632752	63632775	17	-	27260157	RKO	viability	TTCTTCATGGTCTCATATCCAGG	MAP3K3	ENSG00000198909	-1.04843006301324	[]	[]	-8	hSpCas9	negative selection	2803103
63681769	63681792	17	-	27260157	RKO	viability	TGAGCTTCGGCCAGGGTTCTGGG	MAP3K3	ENSG00000198909	0.441018943440331	[]	[]	2	hSpCas9	negative selection	2803172
63632700	63632723	17	+	27260157	RKO	viability	CTCAATCATGAACGATCTGGTGG	MAP3K3	ENSG00000198909	-0.754322438341741	[]	[]	-7	hSpCas9	negative selection	2803825
63632736	63632759	17	-	27260157	RKO	viability	ATCCAGGCATCCGGTGACGTCGG	MAP3K3	ENSG00000198909	0.463146068726514	[]	[]	2	hSpCas9	negative selection	2805960
63666968	63666991	17	-	27260157	RKO	viability	AGCCTTGATCCGCACCTGTCTGG	MAP3K3	ENSG00000198909	0.681053091763718	[]	[]	7	hSpCas9	negative selection	2807199
63622743	63622766	17	-	27260157	RKO	viability	ACCCATGGTGGCGATGGCGGCGG	MAP3K3	ENSG00000198909	-0.969741044073644	[]	[]	-8	hSpCas9	negative selection	2813323
63685564	63685587	17	-	27260157	RKO	viability	CTGCTGACCTGTCCAAGGATTGG	MAP3K3	ENSG00000198909	0.605279166348408	[]	[]	3	hSpCas9	negative selection	2834524
63622755	63622778	17	-	27260157	RKO	viability	GTGGCGACACTTACCCATGGTGG	MAP3K3	ENSG00000198909	-1.20229925334735	[]	[]	-8	hSpCas9	negative selection	2835626
63666966	63666989	17	+	27260157	RKO	viability	GTCCAGACAGGTGCGGATCAAGG	MAP3K3	ENSG00000198909	0.286619899842082	[]	[]	1	hSpCas9	negative selection	2837956
63646043	63646066	17	+	27260157	RKO	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.431628689929306	[]	[]	2	hSpCas9	negative selection	2838010
63632764	63632787	17	+	27260157	RKO	viability	ACCATGAAGAACAAAGACACAGG	MAP3K3	ENSG00000198909	-0.0807002263707143	[]	[]	0	hSpCas9	negative selection	2840128
63632667	63632690	17	+	27260157	RKO	viability	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.795708123771136	[]	[]	8	hSpCas9	negative selection	2842469
63646044	63646067	17	+	27260157	RKO	viability	GAATCAAGTTCGAGCACAACGGG	MAP3K3	ENSG00000198909	0.691282689523017	[]	[]	7	hSpCas9	negative selection	2844444
63632745	63632768	17	-	27260157	RKO	viability	TGGTCTCATATCCAGGCATCCGG	MAP3K3	ENSG00000198909	0.395917854404852	[]	[]	2	hSpCas9	negative selection	2845864
63632697	63632720	17	+	27260157	RKO	viability	GAACTCAATCATGAACGATCTGG	MAP3K3	ENSG00000198909	-0.643445228812382	[]	[]	-7	hSpCas9	negative selection	2847613
63652553	63652576	17	+	27260157	RKO	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.289248396637452	[]	[]	1	hSpCas9	negative selection	2870477
63632734	63632757	17	+	27260157	SF268	viability	AACCGACGTCACCGGATGCCTGG	MAP3K3	ENSG00000198909	1.28159651211107	[]	[]	9	hSpCas9	negative selection	2879213
63632752	63632775	17	-	27260157	SF268	viability	TTCTTCATGGTCTCATATCCAGG	MAP3K3	ENSG00000198909	-0.311056611351519	[]	[]	-2	hSpCas9	negative selection	2879233
63681769	63681792	17	-	27260157	SF268	viability	TGAGCTTCGGCCAGGGTTCTGGG	MAP3K3	ENSG00000198909	-0.382396730876798	[]	[]	-3	hSpCas9	negative selection	2879302
63632700	63632723	17	+	27260157	SF268	viability	CTCAATCATGAACGATCTGGTGG	MAP3K3	ENSG00000198909	-0.693898077829317	[]	[]	-5	hSpCas9	negative selection	2879955
63632736	63632759	17	-	27260157	SF268	viability	ATCCAGGCATCCGGTGACGTCGG	MAP3K3	ENSG00000198909	-0.293129597193283	[]	[]	-2	hSpCas9	negative selection	2882090
63666968	63666991	17	-	27260157	SF268	viability	AGCCTTGATCCGCACCTGTCTGG	MAP3K3	ENSG00000198909	0.284086949897266	[]	[]	4	hSpCas9	negative selection	2883329
63622743	63622766	17	-	27260157	SF268	viability	ACCCATGGTGGCGATGGCGGCGG	MAP3K3	ENSG00000198909	-0.391073229873878	[]	[]	-3	hSpCas9	negative selection	2889453
63685564	63685587	17	-	27260157	SF268	viability	CTGCTGACCTGTCCAAGGATTGG	MAP3K3	ENSG00000198909	0.296635046263654	[]	[]	4	hSpCas9	negative selection	2910654
63622755	63622778	17	-	27260157	SF268	viability	GTGGCGACACTTACCCATGGTGG	MAP3K3	ENSG00000198909	-0.458176414204665	[]	[]	-4	hSpCas9	negative selection	2911756
63666966	63666989	17	+	27260157	SF268	viability	GTCCAGACAGGTGCGGATCAAGG	MAP3K3	ENSG00000198909	-0.0349406960731099	[]	[]	0	hSpCas9	negative selection	2914086
63646043	63646066	17	+	27260157	SF268	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.542473373204476	[]	[]	8	hSpCas9	negative selection	2914140
63632764	63632787	17	+	27260157	SF268	viability	ACCATGAAGAACAAAGACACAGG	MAP3K3	ENSG00000198909	0.529596145610671	[]	[]	8	hSpCas9	negative selection	2916258
63632667	63632690	17	+	27260157	SF268	viability	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.670154522648169	[]	[]	8	hSpCas9	negative selection	2918599
63646044	63646067	17	+	27260157	SF268	viability	GAATCAAGTTCGAGCACAACGGG	MAP3K3	ENSG00000198909	0.267903242553744	[]	[]	4	hSpCas9	negative selection	2920574
63632745	63632768	17	-	27260157	SF268	viability	TGGTCTCATATCCAGGCATCCGG	MAP3K3	ENSG00000198909	-1.422934359804	[]	[]	-8	hSpCas9	negative selection	2921994
63632697	63632720	17	+	27260157	SF268	viability	GAACTCAATCATGAACGATCTGG	MAP3K3	ENSG00000198909	-0.295110222061326	[]	[]	-2	hSpCas9	negative selection	2923743
63652553	63652576	17	+	27260157	SF268	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.262598992544926	[]	[]	-2	hSpCas9	negative selection	2946607
63646046	63646069	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.4305555856211058	[2,2]	[2,3]	8	hSpCas9	positive selection	3001155
63688836	63688859	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.05405586790683349	[3,4]	[3,3]	1	hSpCas9	positive selection	3001156
63688847	63688870	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTGTGGTGCACAGACACGTGG	MAP3K3	ENSG00000198909	-0.3844062218111418	[2,2]	[3,0]	-5	hSpCas9	positive selection	3001157
63688532	63688555	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACATTCGTGATTTCCGGAAGG	MAP3K3	ENSG00000198909	0.30516256377112366	[3,3]	[2,3]	6	hSpCas9	positive selection	3001158
63646046	63646069	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.04060693273479493	[2,2]	[2,0]	0	hSpCas9	positive selection	3069013
63688836	63688859	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.1946405456437099	[3,3]	[2,2]	3	hSpCas9	positive selection	3069014
63688847	63688870	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTGTGGTGCACAGACACGTGG	MAP3K3	ENSG00000198909	-0.4800618316806068	[2,2]	[1,0]	-6	hSpCas9	positive selection	3069015
63688532	63688555	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACATTCGTGATTTCCGGAAGG	MAP3K3	ENSG00000198909	0.35957643643028764	[3,3]	[2,2]	6	hSpCas9	positive selection	3069016
63646043	63646066		+	24336571	A375	resistance to PLX after 7 days	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.4590270104223278	[12,11]	[8,7]	-9	hSpCas9	positive selection	3126293
63652553	63652576		+	24336571	A375	resistance to PLX after 7 days	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.3386367775648106	[19,21]	[28,22]	8	hSpCas9	positive selection	3126294
63646043	63646066		+	24336571	A375	resistance to PLX after 14 days	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-1.030430401312	[10,16]	[2,2]	-9	hSpCas9	positive selection	3184086
63652553	63652576		+	24336571	A375	resistance to PLX after 14 days	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.8676047923965179	[23,20]	[16,20]	7	hSpCas9	positive selection	3184087
63646043	63646066		+	24336571	A375	viability after 7 days	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.4848350509718376	[17]	[12,11]	-6	hSpCas9	negative selection	3241879
63652553	63652576		+	24336571	A375	viability after 7 days	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.2374717003901371	[25]	[19,21]	-3	hSpCas9	negative selection	3241880
63646043	63646066		+	24336571	A375	viability after 14 days	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.22480967132659121	[17]	[10,16]	-3	hSpCas9	negative selection	3299672
63652553	63652576		+	24336571	A375	viability after 14 days	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.11807141471301541	[25]	[23,20]	-1	hSpCas9	negative selection	3299673
63646043	63646066	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.5158592250446882	[106,106]	[0,0]	2	hSpCas9	positive selection	3378414
63652635	63652658	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.6734111261170512	[243,243]	[0,0]	-4	hSpCas9	positive selection	3378415
63690355	63690378	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.4371472490306473	[112,112]	[0,0]	2	hSpCas9	positive selection	3378416
63646045	63646068	17	+	26780180	HT29	viability (Avana library 4 designs)	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.700315671959635	[]	[]	2	hSpCas9	negative selection	3438799
63688836	63688859	17	-	26780180	HT29	viability (Avana library 4 designs)	ACAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	1.29669269880344	[]	[]	5	hSpCas9	negative selection	3438800
63688847	63688870	17	-	26780180	HT29	viability (Avana library 4 designs)	CCTTGTGGTGCACAGACACGTGG	MAP3K3	ENSG00000198909	1.84714312284065	[]	[]	7	hSpCas9	negative selection	3438801
63688532	63688555	17	-	26780180	HT29	viability (Avana library 4 designs)	GGACATTCGTGATTTCCGGAAGG	MAP3K3	ENSG00000198909	1.27676644217156	[]	[]	5	hSpCas9	negative selection	3438802
63688532	63688555	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACATTCGTGATTTCCGGAAGG	MAP3K3	ENSG00000198909	2.09075436680163	[]	[]	3	hSpCas9	negative selection	3528228
63688847	63688870	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTGTGGTGCACAGACACGTGG	MAP3K3	ENSG00000198909	5.3905627015689	[]	[]	8	hSpCas9	negative selection	3528229
63688836	63688859	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	3.9855138784097	[]	[]	6	hSpCas9	negative selection	3528230
63646045	63646068	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-4.32903243659949	[]	[]	-5	hSpCas9	negative selection	3528231
63632723	63632746	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGACGTCGGTTCATCTGGAGGG	MAP3K3	ENSG00000198909	2.5841230848184	[]	[]	4	hSpCas9	negative selection	3528232
63681797	63681820	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	1.87914788213928	[]	[]	2	hSpCas9	negative selection	3528233
63688532	63688555	17	-	26780180	A375	viability (Avana lentiGuide)	GGACATTCGTGATTTCCGGAAGG	MAP3K3	ENSG00000198909	2.68615031299131	[]	[]	3	hSpCas9	negative selection	3636887
63688847	63688870	17	-	26780180	A375	viability (Avana lentiGuide)	CCTTGTGGTGCACAGACACGTGG	MAP3K3	ENSG00000198909	-3.44832799236112	[]	[]	-6	hSpCas9	negative selection	3636888
63688836	63688859	17	-	26780180	A375	viability (Avana lentiGuide)	ACAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	9.39416007115644	[]	[]	6	hSpCas9	negative selection	3636889
63646045	63646068	17	+	26780180	A375	viability (Avana lentiGuide)	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	1.00455435393546	[]	[]	1	hSpCas9	negative selection	3636890
63632723	63632746	17	-	26780180	A375	viability (Avana lentiGuide)	GTGACGTCGGTTCATCTGGAGGG	MAP3K3	ENSG00000198909	-2.03519661441918	[]	[]	-3	hSpCas9	negative selection	3636891
63681797	63681820	17	-	26780180	A375	viability (Avana lentiGuide)	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-1.25544966573468	[]	[]	-2	hSpCas9	negative selection	3636892
63688532	63688555	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACATTCGTGATTTCCGGAAGG	MAP3K3	ENSG00000198909	-0.10153035872163758	[5]	[5,4]	-2	hSpCas9	positive selection	3745546
63688847	63688870	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTGTGGTGCACAGACACGTGG	MAP3K3	ENSG00000198909	0.38542595781370803	[4]	[5,5]	9	hSpCas9	positive selection	3745547
63688836	63688859	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.08924094144825188	[4]	[5,4]	2	hSpCas9	positive selection	3745548
63646045	63646068	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.8842700711707927	[4]	[2,1]	-8	hSpCas9	positive selection	3745549
63632723	63632746	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGACGTCGGTTCATCTGGAGGG	MAP3K3	ENSG00000198909	0.13436117240110873	[5]	[5,5]	3	hSpCas9	positive selection	3745550
63681797	63681820	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	0.006884739888998848	[4]	[4,3]	0	hSpCas9	positive selection	3745551
63688532	63688555	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACATTCGTGATTTCCGGAAGG	MAP3K3	ENSG00000198909	-0.10769840582937915	[5]	[5,3]	-1	hSpCas9	positive selection	3854153
63688847	63688870	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTGTGGTGCACAGACACGTGG	MAP3K3	ENSG00000198909	-1.0776333934843645	[4]	[2,0]	-8	hSpCas9	positive selection	3854154
63688836	63688859	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	-0.19414428827964336	[5]	[3,4]	-3	hSpCas9	positive selection	3854155
63646045	63646068	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.23874781994270122	[4]	[3,4]	6	hSpCas9	positive selection	3854156
63632723	63632746	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGACGTCGGTTCATCTGGAGGG	MAP3K3	ENSG00000198909	0.2247429479572051	[5]	[6,5]	6	hSpCas9	positive selection	3854157
63681797	63681820	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-0.8367123263272699	[4]	[1,1]	-8	hSpCas9	positive selection	3854158
63690355	63690378	17	+	26780180	A375	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	1.77233281251878	[]	[]	9	hSpCas9	negative selection	3959673
63646043	63646066	17	+	26780180	A375	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.434508006671222	[]	[]	1	hSpCas9	negative selection	3959674
63690315	63690338	17	-	26780180	A375	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.711918424728973	[]	[]	2	hSpCas9	negative selection	3959675
63690325	63690348	17	+	26780180	A375	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	1.34076051231019	[]	[]	7	hSpCas9	negative selection	3959676
63652553	63652576	17	+	26780180	A375	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	1.40249955252266	[]	[]	7	hSpCas9	negative selection	3959677
63652635	63652658	17	+	26780180	A375	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	1.13713445088182	[]	[]	6	hSpCas9	negative selection	3959678
63690355	63690378	17	+	26780180	HT29	viability (GeCKOv2 library)	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	1.62116710632951	[]	[]	8	hSpCas9	negative selection	4067639
63646043	63646066	17	+	26780180	HT29	viability (GeCKOv2 library)	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.816273504535237	[]	[]	3	hSpCas9	negative selection	4067640
63690315	63690338	17	-	26780180	HT29	viability (GeCKOv2 library)	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	1.10382036496589	[]	[]	5	hSpCas9	negative selection	4067641
63690325	63690348	17	+	26780180	HT29	viability (GeCKOv2 library)	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	0.806896693385038	[]	[]	3	hSpCas9	negative selection	4067642
63652553	63652576	17	+	26780180	HT29	viability (GeCKOv2 library)	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	1.57856392144035	[]	[]	8	hSpCas9	negative selection	4067643
63652635	63652658	17	+	26780180	HT29	viability (GeCKOv2 library)	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.919307962454261	[]	[]	4	hSpCas9	negative selection	4067644
63646043	63646066	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.6790268640448966	[3]	[0,1]	-9	hSpCas9	positive selection	4150510
63652553	63652576	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.40133339720669137	[4]	[3,4]	8	hSpCas9	positive selection	4150511
63646043	63646066	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.09762566885296872	[4]	[3,2,2,0]	0	hSpCas9	positive selection	4214532
63652553	63652576	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.8380835260252912	[2]	[0,1,1,2]	5	hSpCas9	positive selection	4214533
63690315	63690338	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.36869673651496604	[1]	[0,0]	-7	hSpCas9	positive selection	4281843
63652553	63652576	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.6514890618933218	[3]	[1,0]	-9	hSpCas9	positive selection	4281844
63690325	63690348	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.3616779677941834	[2]	[2,0]	-6	hSpCas9	positive selection	4281845
63646043	63646066	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.20990361558970544	[2]	[2,1]	4	hSpCas9	positive selection	4346101
63652635	63652658	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.06054696525481862	[3]	[3,1]	1	hSpCas9	positive selection	4346102
63690355	63690378	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.276205590541823	[2]	[1,1]	-5	hSpCas9	positive selection	4346103
63688836	63688858	17	-	27760321	OCIAML3	viability	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	-0.3631201813501873	[807,646]	[365,535]	-4	hSpCas9	negative selection	4416609
63646046	63646068	17	+	27760321	OCIAML3	viability	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.22605114193275755	[576,494]	[523,442]	2	hSpCas9	negative selection	4416610
63652554	63652576	17	+	27760321	OCIAML3	viability	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.7311323734585207	[462,410]	[149,277]	-6	hSpCas9	negative selection	4416611
63666993	63667015	17	-	27760321	OCIAML3	viability	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	0.42496228296312066	[444,376]	[337,549]	5	hSpCas9	negative selection	4416612
63681886	63681908	17	-	27760321	OCIAML3	viability	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	0.08495993958187964	[1034,962]	[752,927]	1	hSpCas9	negative selection	4416613
63688836	63688858	17	-	27760321	OCIAML2	viability	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.07674324760735318	[807,646]	[522,740]	1	hSpCas9	negative selection	4500072
63646046	63646068	17	+	27760321	OCIAML2	viability	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.19756480863922765	[576,494]	[427,584]	2	hSpCas9	negative selection	4500073
63652554	63652576	17	+	27760321	OCIAML2	viability	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.31714440458963117	[462,410]	[218,367]	-4	hSpCas9	negative selection	4500074
63666993	63667015	17	-	27760321	OCIAML2	viability	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	0.48775266457021554	[444,376]	[502,413]	6	hSpCas9	negative selection	4500075
63681886	63681908	17	-	27760321	OCIAML2	viability	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	0.28076913979740636	[1034,962]	[821,1192]	4	hSpCas9	negative selection	4500076
63688836	63688858	17	-	27760321	MV411	viability	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.9388990354925002	[807,646]	[918,908]	7	hSpCas9	negative selection	4583535
63646046	63646068	17	+	27760321	MV411	viability	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.9844685978716995	[576,494]	[628,800]	7	hSpCas9	negative selection	4583536
63652554	63652576	17	+	27760321	MV411	viability	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.8014687014954529	[462,410]	[159,172]	-5	hSpCas9	negative selection	4583537
63666993	63667015	17	-	27760321	MV411	viability	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	0.5671324920706583	[444,376]	[427,358]	4	hSpCas9	negative selection	4583538
63681886	63681908	17	-	27760321	MV411	viability	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	0.009279899880108022	[1034,962]	[315,1185]	0	hSpCas9	negative selection	4583539
63688836	63688858	17	-	27760321	HL60	viability	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.16707995668479836	[807,646]	[592,737]	2	hSpCas9	negative selection	4666998
63646046	63646068	17	+	27760321	HL60	viability	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.7039768329890923	[576,494]	[316,215]	-6	hSpCas9	negative selection	4666999
63652554	63652576	17	+	27760321	HL60	viability	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.06091121153893422	[462,410]	[413,326]	0	hSpCas9	negative selection	4667000
63666993	63667015	17	-	27760321	HL60	viability	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	0.14220911957024757	[444,376]	[276,466]	1	hSpCas9	negative selection	4667001
63681886	63681908	17	-	27760321	HL60	viability	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	0.06723684388664353	[1034,962]	[681,1038]	0	hSpCas9	negative selection	4667002
63688836	63688858	17	-	27760321	HT1080	viability	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.9192856153687159	[646,504]	[569,284]	5	hSpCas9	negative selection	4750461
63646046	63646068	17	+	27760321	HT1080	viability	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.06320651405424083	[494,385]	[187,145]	0	hSpCas9	negative selection	4750462
63652554	63652576	17	+	27760321	HT1080	viability	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.42406774590907326	[410,320]	[208,180]	2	hSpCas9	negative selection	4750463
63666993	63667015	17	-	27760321	HT1080	viability	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	0.35206944517770833	[376,293]	[203,133]	1	hSpCas9	negative selection	4750464
63681886	63681908	17	-	27760321	HT1080	viability	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	-0.30237388949614563	[962,751]	[287,264]	-1	hSpCas9	negative selection	4750465
63688836	63688858	17	-	27760321	HT29	viability after 7 days	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.2579437553892202	[646,504]	[1057,609,1007]	4	hSpCas9	negative selection	4833924
63646046	63646068	17	+	27760321	HT29	viability after 7 days	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.19435431957473803	[494,385]	[678,419,413]	-3	hSpCas9	negative selection	4833925
63652554	63652576	17	+	27760321	HT29	viability after 7 days	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.3399164266559585	[410,320]	[385,361,368]	-5	hSpCas9	negative selection	4833926
63666993	63667015	17	-	27760321	HT29	viability after 7 days	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	-0.18947564413337836	[376,293]	[477,405,267]	-3	hSpCas9	negative selection	4833927
63681886	63681908	17	-	27760321	HT29	viability after 7 days	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	-0.4480943323044432	[962,751]	[746,966,703]	-6	hSpCas9	negative selection	4833928
63688836	63688858	17	-	27760321	HT29	viability after 25 days	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.10701674457679777	[646,504]	[524,742,887]	1	hSpCas9	negative selection	4917387
63646046	63646068	17	+	27760321	HT29	viability after 25 days	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.018757108621405227	[494,385]	[467,601,412]	0	hSpCas9	negative selection	4917388
63652554	63652576	17	+	27760321	HT29	viability after 25 days	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.8639657101076832	[410,320]	[203,228,260]	-6	hSpCas9	negative selection	4917389
63666993	63667015	17	-	27760321	HT29	viability after 25 days	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	0.10203745371800574	[376,293]	[379,399,460]	1	hSpCas9	negative selection	4917390
63681886	63681908	17	-	27760321	HT29	viability after 25 days	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	0.03581336937521207	[962,751]	[848,1152,1021]	0	hSpCas9	negative selection	4917391
63688836	63688858	17	-	27760321	HT29	viability after 22 days	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.11584235110090335	[646,504]	[814,638,707]	1	hSpCas9	negative selection	5000850
63646046	63646068	17	+	27760321	HT29	viability after 22 days	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.21527459933824378	[494,385]	[558,552,662]	2	hSpCas9	negative selection	5000851
63652554	63652576	17	+	27760321	HT29	viability after 22 days	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.721889497826834	[410,320]	[242,269,256]	-6	hSpCas9	negative selection	5000852
63666993	63667015	17	-	27760321	HT29	viability after 22 days	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	-0.1212055002417358	[376,293]	[374,257,436]	-1	hSpCas9	negative selection	5000853
63681886	63681908	17	-	27760321	HT29	viability after 22 days	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	-0.33267159802749446	[962,751]	[809,860,688]	-3	hSpCas9	negative selection	5000854
63688836	63688858	17	-	27760321	HT29	viability after 19 days	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.38660474716351434	[646,504]	[851,866,862]	4	hSpCas9	negative selection	5084313
63646046	63646068	17	+	27760321	HT29	viability after 19 days	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.06072058591868157	[494,385]	[679,598,320]	0	hSpCas9	negative selection	5084314
63652554	63652576	17	+	27760321	HT29	viability after 19 days	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.30675590690038507	[410,320]	[304,433,274]	-3	hSpCas9	negative selection	5084315
63666993	63667015	17	-	27760321	HT29	viability after 19 days	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	-0.10693103972538993	[376,293]	[328,226,503]	-1	hSpCas9	negative selection	5084316
63681886	63681908	17	-	27760321	HT29	viability after 19 days	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	-0.345151534871881	[962,751]	[807,620,885]	-3	hSpCas9	negative selection	5084317
63688836	63688858	17	-	27760321	HT29	viability after 16 days	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.3428644913268797	[646,504]	[637,1080,708]	4	hSpCas9	negative selection	5167776
63646046	63646068	17	+	27760321	HT29	viability after 16 days	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.1663931763018604	[494,385]	[671,334,668]	1	hSpCas9	negative selection	5167777
63652554	63652576	17	+	27760321	HT29	viability after 16 days	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.8926043431498994	[410,320]	[237,194,230]	-6	hSpCas9	negative selection	5167778
63666993	63667015	17	-	27760321	HT29	viability after 16 days	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	-0.21926817266864446	[376,293]	[352,210,408]	-2	hSpCas9	negative selection	5167779
63681886	63681908	17	-	27760321	HT29	viability after 16 days	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	-0.21998718513420723	[962,751]	[681,924,847]	-2	hSpCas9	negative selection	5167780
63688836	63688858	17	-	27760321	HT29	viability after 13 days	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	0.17203261707769757	[646,504]	[668,655,922]	2	hSpCas9	negative selection	5251239
63646046	63646068	17	+	27760321	HT29	viability after 13 days	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.1831010016616893	[494,385]	[496,517,716]	2	hSpCas9	negative selection	5251240
63652554	63652576	17	+	27760321	HT29	viability after 13 days	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.9696748219374337	[410,320]	[152,219,273]	-7	hSpCas9	negative selection	5251241
63666993	63667015	17	-	27760321	HT29	viability after 13 days	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	0.1358432940255828	[376,293]	[433,424,423]	1	hSpCas9	negative selection	5251242
63681886	63681908	17	-	27760321	HT29	viability after 13 days	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	-0.38930750201900244	[962,751]	[753,1011,526]	-4	hSpCas9	negative selection	5251243
63688836	63688858	17	-	27760321	HT29	viability after 10 days	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	-0.1806571817775342	[646,504]	[609,615,675]	-2	hSpCas9	negative selection	5334702
63646046	63646068	17	+	27760321	HT29	viability after 10 days	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.14591946459667499	[494,385]	[647,522,650]	2	hSpCas9	negative selection	5334703
63652554	63652576	17	+	27760321	HT29	viability after 10 days	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-1.3078884700009168	[410,320]	[106,284,164]	-8	hSpCas9	negative selection	5334704
63666993	63667015	17	-	27760321	HT29	viability after 10 days	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	0.14137282097912163	[376,293]	[366,325,683]	1	hSpCas9	negative selection	5334705
63681886	63681908	17	-	27760321	HT29	viability after 10 days	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	-0.49379143480926535	[962,751]	[778,833,671]	-6	hSpCas9	negative selection	5334706
63688836	63688858	17	-	27760321	MOLM13	viability	CAGACACGTGGTAGCGCCGGGG	MAP3K3	ENSG00000198909	1.0966660003429525	[807,646]	[869,874]	7	hSpCas9	negative selection	5418165
63646046	63646068	17	+	27760321	MOLM13	viability	ATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.004525467242439296	[576,494]	[403,215]	0	hSpCas9	negative selection	5418166
63652554	63652576	17	+	27760321	MOLM13	viability	CAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.9510510546746072	[462,410]	[362,571]	6	hSpCas9	negative selection	5418167
63666993	63667015	17	-	27760321	MOLM13	viability	ATTTATATCCCCTGCGGACTGG	MAP3K3	ENSG00000198909	1.6141616062434414	[444,376]	[217,1123]	9	hSpCas9	negative selection	5418168
63681886	63681908	17	-	27760321	MOLM13	viability	ATACTCACGCACTGCTCGCTGG	MAP3K3	ENSG00000198909	-0.3884930639993126	[1034,962]	[521,352]	-3	hSpCas9	negative selection	5418169
63622429	63622452	17	+	27661255	K562	viability	GTTCCTGAGGTGGAGAACGGTGG	MAP3K3	ENSG00000198909	0.062888089924514	[844,981]	[845,686]	2	dCas9-KRAB	negative selection	5492103
63622437	63622460	17	+	27661255	K562	viability	GGTGGAGAACGGTGGCCGGACGG	MAP3K3	ENSG00000198909	0.13794831824724263	[896,907]	[906,695]	5	dCas9-KRAB	negative selection	5492104
63622448	63622471	17	+	27661255	K562	viability	GTGGCCGGACGGAGAGACTGCGG	MAP3K3	ENSG00000198909	0.33358745844833726	[913,1126]	[1031,1015]	9	dCas9-KRAB	negative selection	5492105
63622837	63622860	17	-	27661255	K562	viability	GCCTGTCAGGCGGTGGCCCAGGG	MAP3K3	ENSG00000198909	0.12252601452151818	[561,526]	[486,462]	4	dCas9-KRAB	negative selection	5492106
63690315	63690338	17	-	27260156	BXPC3	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.18070137366531114	[84]	[101,95,106,96]	4	hSpCas9	negative selection	5554303
63652553	63652576	17	+	27260156	BXPC3	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.04895345474118326	[483]	[432,451,443,651]	-1	hSpCas9	negative selection	5554304
63690325	63690348	17	+	27260156	BXPC3	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.09735403192634817	[269]	[230,183,378,270]	-2	hSpCas9	negative selection	5554305
63646043	63646066	17	+	27260156	BXPC3	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.2293443555904699	[283]	[305,304,338,460]	5	hSpCas9	negative selection	5618561
63652635	63652658	17	+	27260156	BXPC3	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.08755014245326406	[573]	[618,454,467,732]	-2	hSpCas9	negative selection	5618562
63690355	63690378	17	+	27260156	BXPC3	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.1812096691136985	[319]	[255,231,382,319]	-4	hSpCas9	negative selection	5618563
63690315	63690338	17	-	27260156	A673	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.06548926894010654	[84]	[64,96,139,82]	-2	hSpCas9	negative selection	5675554
63652553	63652576	17	+	27260156	A673	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.019750871301722255	[483]	[621,491,498,693]	0	hSpCas9	negative selection	5675555
63690325	63690348	17	+	27260156	A673	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.08558456039770101	[269]	[389,233,319,287]	-2	hSpCas9	negative selection	5675556
63646043	63646066	17	+	27260156	A673	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.02236763437245748	[283]	[414,291,282,407]	0	hSpCas9	negative selection	5739812
63652635	63652658	17	+	27260156	A673	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.08510811713394073	[573]	[913,596,687,749]	2	hSpCas9	negative selection	5739813
63690355	63690378	17	+	27260156	A673	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.02841371200704257	[319]	[427,425,261,396]	0	hSpCas9	negative selection	5739814
63690315	63690338	17	-	27260156	A375	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.0732400383527656	[84]	[98,144,71,70]	-1	hSpCas9	negative selection	5796805
63652553	63652576	17	+	27260156	A375	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.19962210204038436	[483]	[811,863,555,420]	3	hSpCas9	negative selection	5796806
63690325	63690348	17	+	27260156	A375	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.22616449716820486	[269]	[200,253,389,233]	-3	hSpCas9	negative selection	5796807
63646043	63646066	17	+	27260156	A375	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.0429663039511472	[283]	[330,381,462,210]	0	hSpCas9	negative selection	5861063
63652635	63652658	17	+	27260156	A375	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.054643177538680976	[573]	[586,792,892,540]	0	hSpCas9	negative selection	5861064
63690355	63690378	17	+	27260156	A375	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.14657820881854422	[319]	[472,281,281,308]	-2	hSpCas9	negative selection	5861065
63690315	63690338	17	-	27260156	COLO741	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.16776262485448568	[84]	[157,78,130]	3	hSpCas9	negative selection	5918056
63652553	63652576	17	+	27260156	COLO741	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.14785971534472037	[483]	[527,573,567]	-3	hSpCas9	negative selection	5918057
63690325	63690348	17	+	27260156	COLO741	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	0.09335502732322754	[269]	[527,240,348]	2	hSpCas9	negative selection	5918058
63646043	63646066	17	+	27260156	COLO741	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.13935655598951502	[283]	[393,408,394]	3	hSpCas9	negative selection	5982314
63652635	63652658	17	+	27260156	COLO741	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.1670387500315404	[573]	[980,767,738]	3	hSpCas9	negative selection	5982315
63690355	63690378	17	+	27260156	COLO741	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.09299452890309656	[319]	[494,371,297]	-2	hSpCas9	negative selection	5982316
63690315	63690338	17	-	27260156	CAL120	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.5380775404104328	[84]	[51,69,92]	-6	hSpCas9	negative selection	6039307
63652553	63652576	17	+	27260156	CAL120	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.26169658126456147	[483]	[412,496,581]	-4	hSpCas9	negative selection	6039308
63690325	63690348	17	+	27260156	CAL120	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.7400841731421506	[269]	[247,248,114]	-8	hSpCas9	negative selection	6039309
63646043	63646066	17	+	27260156	CAL120	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.1214186953836639	[283]	[524,359,290]	1	hSpCas9	negative selection	6103565
63652635	63652658	17	+	27260156	CAL120	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.006032896228100493	[573]	[975,695,521]	0	hSpCas9	negative selection	6103566
63690355	63690378	17	+	27260156	CAL120	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.3484676850375078	[319]	[430,271,253]	-5	hSpCas9	negative selection	6103567
63690315	63690338	17	-	27260156	CADOES1	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.702803933153366	[84]	[38,24,36,94]	-8	hSpCas9	negative selection	6160558
63652553	63652576	17	+	27260156	CADOES1	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.09000457335647802	[483]	[426,470,452,568]	1	hSpCas9	negative selection	6160559
63690325	63690348	17	+	27260156	CADOES1	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.30271403060657254	[269]	[181,131,276,223]	-5	hSpCas9	negative selection	6160560
63646043	63646066	17	+	27260156	CADOES1	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.004694310557411652	[283]	[270,233,259,288]	0	hSpCas9	negative selection	6224816
63652635	63652658	17	+	27260156	CADOES1	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.25931433066257153	[573]	[522,369,361,531]	-4	hSpCas9	negative selection	6224817
63690355	63690378	17	+	27260156	CADOES1	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.00579629318774133	[319]	[409,283,226,272]	0	hSpCas9	negative selection	6224818
63690315	63690338	17	-	27260156	EWS502	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.038853236285375736	[84]	[80,88,77,103]	0	hSpCas9	negative selection	6281809
63652553	63652576	17	+	27260156	EWS502	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.0017066481102925163	[483]	[403,599,508,544]	0	hSpCas9	negative selection	6281810
63690325	63690348	17	+	27260156	EWS502	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.13687218683660451	[269]	[216,268,310,246]	-2	hSpCas9	negative selection	6281811
63646043	63646066	17	+	27260156	EWS502	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.07325577452943921	[283]	[307,338,261,357]	1	hSpCas9	negative selection	6346067
63652635	63652658	17	+	27260156	EWS502	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.08525648282114606	[573]	[397,737,665,813]	1	hSpCas9	negative selection	6346068
63690355	63690378	17	+	27260156	EWS502	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.16338466902669346	[319]	[339,229,412,557]	3	hSpCas9	negative selection	6346069
63690315	63690338	17	-	27260156	EW8	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.009500427926446342	[84]	[120,19,114,18]	0	hSpCas9	negative selection	6403060
63652553	63652576	17	+	27260156	EW8	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.17585544988455096	[483]	[397,346,338,310]	-3	hSpCas9	negative selection	6403061
63690325	63690348	17	+	27260156	EW8	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	0.21455510359600916	[269]	[288,301,152,291]	4	hSpCas9	negative selection	6403062
63646043	63646066	17	+	27260156	EW8	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.15996006665723805	[283]	[236,289,213,291]	3	hSpCas9	negative selection	6467318
63652635	63652658	17	+	27260156	EW8	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.0022043605817009815	[573]	[726,466,373,338]	0	hSpCas9	negative selection	6467319
63690355	63690378	17	+	27260156	EW8	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.10510677948475872	[319]	[407,260,226,241]	2	hSpCas9	negative selection	6467320
63690315	63690338	17	-	27260156	CORL105	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.03090988210827117	[84]	[32,170,78,99]	0	hSpCas9	negative selection	6524311
63652553	63652576	17	+	27260156	CORL105	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.25609015163805793	[483]	[431,428,594,459]	-5	hSpCas9	negative selection	6524312
63690325	63690348	17	+	27260156	CORL105	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.24282096878129855	[269]	[317,230,273,248]	-4	hSpCas9	negative selection	6524313
63646043	63646066	17	+	27260156	CORL105	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.023096289517553825	[283]	[305,365,402,284]	0	hSpCas9	negative selection	6588569
63652635	63652658	17	+	27260156	CORL105	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.04001349449468733	[573]	[710,663,831,579]	0	hSpCas9	negative selection	6588570
63690355	63690378	17	+	27260156	CORL105	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.16549064590299833	[319]	[360,229,398,358]	-3	hSpCas9	negative selection	6588571
63690315	63690338	17	-	27260156	HS294T	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.05074918182679822	[84]	[45,20,30,26]	0	hSpCas9	negative selection	6645562
63652553	63652576	17	+	27260156	HS294T	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.37078140153780415	[483]	[123,124,162,173]	-5	hSpCas9	negative selection	6645563
63690325	63690348	17	+	27260156	HS294T	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.28993332071818223	[269]	[56,103,88,94]	-4	hSpCas9	negative selection	6645564
63646043	63646066	17	+	27260156	HS294T	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.4513890860812103	[283]	[117,57,51,91]	-6	hSpCas9	negative selection	6709820
63652635	63652658	17	+	27260156	HS294T	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.15149275727228306	[573]	[200,223,140,237]	-2	hSpCas9	negative selection	6709821
63690355	63690378	17	+	27260156	HS294T	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.3377589021387186	[319]	[135,137,224,122]	4	hSpCas9	negative selection	6709822
63690315	63690338	17	-	27260156	HCC44	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.36101765974099953	[84]	[112,23,110,67]	-5	hSpCas9	negative selection	6766813
63652553	63652576	17	+	27260156	HCC44	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.09534773822928563	[483]	[461,542,799,561]	1	hSpCas9	negative selection	6766814
63690325	63690348	17	+	27260156	HCC44	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.45085137380486606	[269]	[293,153,284,186]	-6	hSpCas9	negative selection	6766815
63646043	63646066	17	+	27260156	HCC44	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.040801552294281174	[283]	[271,300,304,431]	0	hSpCas9	negative selection	6831071
63652635	63652658	17	+	27260156	HCC44	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.13376674661355975	[573]	[774,428,1053,690]	2	hSpCas9	negative selection	6831072
63690355	63690378	17	+	27260156	HCC44	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.00506906648565475	[319]	[481,245,297,427]	0	hSpCas9	negative selection	6831073
63690315	63690338	17	-	27260156	G402	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.48025436711772596	[84]	[16,145,76,53]	-5	hSpCas9	negative selection	6888064
63652553	63652576	17	+	27260156	G402	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.04723260320246793	[483]	[662,600,684,501]	0	hSpCas9	negative selection	6888065
63690325	63690348	17	+	27260156	G402	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.5738318899733312	[269]	[190,464,95,145]	-6	hSpCas9	negative selection	6888066
63646043	63646066	17	+	27260156	G402	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.2925587325110231	[283]	[833,296,364,259]	3	hSpCas9	negative selection	6952322
63652635	63652658	17	+	27260156	G402	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.03231497255935295	[573]	[895,920,533,556]	0	hSpCas9	negative selection	6952323
63690355	63690378	17	+	27260156	G402	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.26196500904171505	[319]	[308,478,283,239]	-3	hSpCas9	negative selection	6952324
63690315	63690338	17	-	27260156	L33	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.002727910521006738	[84]	[62,41,49,95]	0	hSpCas9	negative selection	7009315
63652553	63652576	17	+	27260156	L33	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.008769948695095085	[483]	[402,212,351,443]	0	hSpCas9	negative selection	7009316
63690325	63690348	17	+	27260156	L33	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	0.3396252756595716	[269]	[367,128,237,304]	7	hSpCas9	negative selection	7009317
63646043	63646066	17	+	27260156	L33	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.01330701375369836	[283]	[282,141,139,272]	0	hSpCas9	negative selection	7073573
63652635	63652658	17	+	27260156	L33	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.24544956488049985	[573]	[679,291,514,511]	5	hSpCas9	negative selection	7073574
63690355	63690378	17	+	27260156	L33	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.042301331305846346	[319]	[362,100,234,333]	1	hSpCas9	negative selection	7073575
63690315	63690338	17	-	27260156	K562	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.5190164530492511	[84]	[116,234,32,59]	6	hSpCas9	negative selection	7130566
63652553	63652576	17	+	27260156	K562	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.05194592119814245	[483]	[415,510,622,252]	0	hSpCas9	negative selection	7130567
63690325	63690348	17	+	27260156	K562	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	0.7541821373528983	[269]	[492,173,236,673]	8	hSpCas9	negative selection	7130568
63646043	63646066	17	+	27260156	K562	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.2925184183099149	[283]	[383,443,197,229]	3	hSpCas9	negative selection	7194824
63652635	63652658	17	+	27260156	K562	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.2850911505642656	[573]	[666,948,555,359]	3	hSpCas9	negative selection	7194825
63690355	63690378	17	+	27260156	K562	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.096673940836699	[319]	[287,162,457,160]	-1	hSpCas9	negative selection	7194826
63690315	63690338	17	-	27260156	HT29	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.28515745603019127	[84]	[52,135,97,56]	-5	hSpCas9	negative selection	7251817
63652553	63652576	17	+	27260156	HT29	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.05463485870393789	[483]	[495,687,472,604]	-1	hSpCas9	negative selection	7251818
63690325	63690348	17	+	27260156	HT29	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.20280593789592305	[269]	[367,226,259,284]	-4	hSpCas9	negative selection	7251819
63646043	63646066	17	+	27260156	HT29	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.011588741288070525	[283]	[385,369,385,262]	0	hSpCas9	negative selection	7316075
63652635	63652658	17	+	27260156	HT29	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.3766646054838628	[573]	[660,1099,849,992]	7	hSpCas9	negative selection	7316076
63690355	63690378	17	+	27260156	HT29	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.21996443412248357	[319]	[353,300,430,255]	-4	hSpCas9	negative selection	7316077
63690315	63690338	17	-	27260156	MHHES1	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.5089252326055347	[84]	[208,62,93,168]	8	hSpCas9	negative selection	7373068
63652553	63652576	17	+	27260156	MHHES1	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.326592487329443	[483]	[504,335,389,483]	-6	hSpCas9	negative selection	7373069
63690325	63690348	17	+	27260156	MHHES1	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	0.2343498744010286	[269]	[308,354,497,274]	4	hSpCas9	negative selection	7373070
63646043	63646066	17	+	27260156	MHHES1	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.07924527934581171	[283]	[288,310,410,213]	-1	hSpCas9	negative selection	7437326
63652635	63652658	17	+	27260156	MHHES1	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.10537812999593693	[573]	[897,584,628,671]	2	hSpCas9	negative selection	7437327
63690355	63690378	17	+	27260156	MHHES1	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.06141298660014549	[319]	[551,428,250,305]	1	hSpCas9	negative selection	7437328
63690315	63690338	17	-	27260156	MEWO	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.0017351161977758878	[84]	[49,99,82]	0	hSpCas9	negative selection	7494319
63652553	63652576	17	+	27260156	MEWO	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.40237821742772106	[483]	[476,294,281]	-7	hSpCas9	negative selection	7494320
63690325	63690348	17	+	27260156	MEWO	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.252480443801806	[269]	[304,232,115]	-5	hSpCas9	negative selection	7494321
63646043	63646066	17	+	27260156	MEWO	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.13552822565050782	[283]	[278,193,259]	-3	hSpCas9	negative selection	7558577
63652635	63652658	17	+	27260156	MEWO	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.017810218589373206	[573]	[529,544,515]	0	hSpCas9	negative selection	7558578
63690355	63690378	17	+	27260156	MEWO	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.060300442476334426	[319]	[286,215,428]	1	hSpCas9	negative selection	7558579
63690315	63690338	17	-	27260156	LNCAPCLONEFGC	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.19211863515897454	[84]	[59,102,152,44]	3	hSpCas9	negative selection	7615570
63652553	63652576	17	+	27260156	LNCAPCLONEFGC	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.007178343786864154	[483]	[452,402,539,365]	0	hSpCas9	negative selection	7615571
63690325	63690348	17	+	27260156	LNCAPCLONEFGC	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.34546570643418706	[269]	[203,154,157,249]	-5	hSpCas9	negative selection	7615572
63646043	63646066	17	+	27260156	LNCAPCLONEFGC	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.32135566791310965	[283]	[295,349,427,225]	5	hSpCas9	negative selection	7679828
63652635	63652658	17	+	27260156	LNCAPCLONEFGC	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.12929931723275923	[573]	[602,423,700,574]	2	hSpCas9	negative selection	7679829
63690355	63690378	17	+	27260156	LNCAPCLONEFGC	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.17362083275973372	[319]	[442,221,385,269]	2	hSpCas9	negative selection	7679830
63690315	63690338	17	-	27260156	PANC0327	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.15871692290835204	[84]	[93,30,183,35]	2	hSpCas9	negative selection	7736821
63652553	63652576	17	+	27260156	PANC0327	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.09507868095772443	[483]	[567,240,250,583]	-1	hSpCas9	negative selection	7736822
63690325	63690348	17	+	27260156	PANC0327	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.0796128654581213	[269]	[229,279,124,265]	-1	hSpCas9	negative selection	7736823
63646043	63646066	17	+	27260156	PANC0327	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.19060561818994848	[283]	[231,218,377,326]	3	hSpCas9	negative selection	7801079
63652635	63652658	17	+	27260156	PANC0327	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.09421738573972718	[573]	[374,507,436,577]	-1	hSpCas9	negative selection	7801080
63690355	63690378	17	+	27260156	PANC0327	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.19949178359043557	[319]	[440,346,167,355]	3	hSpCas9	negative selection	7801081
63690315	63690338	17	-	27260156	NCIH2009	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.16963867042860592	[84]	[179,65,85]	-2	hSpCas9	negative selection	7858072
63652553	63652576	17	+	27260156	NCIH2009	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.008950938839691641	[483]	[807,644,612]	0	hSpCas9	negative selection	7858073
63690325	63690348	17	+	27260156	NCIH2009	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.22930096888278095	[269]	[433,267,285]	-3	hSpCas9	negative selection	7858074
63646043	63646066	17	+	27260156	NCIH2009	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.04088775365374864	[283]	[534,383,266]	0	hSpCas9	negative selection	7922330
63652635	63652658	17	+	27260156	NCIH2009	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.11314091659382361	[573]	[854,609,782]	-1	hSpCas9	negative selection	7922331
63690355	63690378	17	+	27260156	NCIH2009	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.09512359070307874	[319]	[430,734,251]	1	hSpCas9	negative selection	7922332
63690315	63690338	17	-	27260156	NCIH1373	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.5182286781077243	[84]	[188,27,39,7]	-5	hSpCas9	negative selection	7979323
63652553	63652576	17	+	27260156	NCIH1373	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.232949204920502	[483]	[861,453,586,184]	2	hSpCas9	negative selection	7979324
63690325	63690348	17	+	27260156	NCIH1373	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.5362778044340104	[269]	[369,131,156,54]	-5	hSpCas9	negative selection	7979325
63646043	63646066	17	+	27260156	NCIH1373	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.4778595579646411	[283]	[512,697,293,62]	5	hSpCas9	negative selection	8043581
63652635	63652658	17	+	27260156	NCIH1373	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.33925216928201707	[573]	[704,523,412,108]	-3	hSpCas9	negative selection	8043582
63690355	63690378	17	+	27260156	NCIH1373	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.044947777704616554	[319]	[374,459,401,33]	0	hSpCas9	negative selection	8043583
63690315	63690338	17	-	27260156	PATU8902	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.6372897498140015	[84]	[50,160,41,56]	-6	hSpCas9	negative selection	8100574
63652553	63652576	17	+	27260156	PATU8902	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.4363280764285643	[483]	[559,729,300,441]	-4	hSpCas9	negative selection	8100575
63690325	63690348	17	+	27260156	PATU8902	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.3311161423108966	[269]	[233,308,373,251]	-3	hSpCas9	negative selection	8100576
63646043	63646066	17	+	27260156	PATU8902	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.09511657791327066	[283]	[196,541,386,347]	-1	hSpCas9	negative selection	8164832
63652635	63652658	17	+	27260156	PATU8902	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.2533166560910783	[573]	[730,971,511,480]	-3	hSpCas9	negative selection	8164833
63690355	63690378	17	+	27260156	PATU8902	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.133459976303967	[319]	[609,800,113,527]	1	hSpCas9	negative selection	8164834
63690315	63690338	17	-	27260156	PANC1	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.21629157554900402	[84]	[39,101,94,27]	-3	hSpCas9	negative selection	8221825
63652553	63652576	17	+	27260156	PANC1	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.040015139655930676	[483]	[363,664,337,390]	0	hSpCas9	negative selection	8221826
63690325	63690348	17	+	27260156	PANC1	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	0.2024566021027201	[269]	[280,235,349,200]	3	hSpCas9	negative selection	8221827
63646043	63646066	17	+	27260156	PANC1	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.3414194096722369	[283]	[223,295,368,336]	5	hSpCas9	negative selection	8286083
63652635	63652658	17	+	27260156	PANC1	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.022481052079044994	[573]	[459,545,545,459]	0	hSpCas9	negative selection	8286084
63690355	63690378	17	+	27260156	PANC1	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.22847286933974387	[319]	[433,433,306,155]	3	hSpCas9	negative selection	8286085
63690315	63690338	17	-	27260156	PANC0813	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.33042060737166734	[84]	[86,76,194,138]	5	hSpCas9	negative selection	8343076
63652553	63652576	17	+	27260156	PANC0813	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.03507791985754105	[483]	[790,480,681,404]	0	hSpCas9	negative selection	8343077
63690325	63690348	17	+	27260156	PANC0813	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	0.43246900918357567	[269]	[330,721,302,349]	7	hSpCas9	negative selection	8343078
63646043	63646066	17	+	27260156	PANC0813	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.2393708322218065	[283]	[488,418,352,325]	4	hSpCas9	negative selection	8407334
63652635	63652658	17	+	27260156	PANC0813	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.003711099009630514	[573]	[888,583,657,595]	0	hSpCas9	negative selection	8407335
63690355	63690378	17	+	27260156	PANC0813	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.07602924101622033	[319]	[335,400,420,270]	-1	hSpCas9	negative selection	8407336
63690315	63690338	17	-	27260156	RDES	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.6448139326454867	[84]	[63,68,53,58]	-8	hSpCas9	negative selection	8464327
63652553	63652576	17	+	27260156	RDES	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.03875045839980379	[483]	[405,521,621,652]	0	hSpCas9	negative selection	8464328
63690325	63690348	17	+	27260156	RDES	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.3510768888208715	[269]	[220,166,237,371]	-5	hSpCas9	negative selection	8464329
63646043	63646066	17	+	27260156	RDES	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.32483156997220314	[283]	[332,387,496,430]	5	hSpCas9	negative selection	8528585
63652635	63652658	17	+	27260156	RDES	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.16422980528480768	[573]	[500,592,541,741]	-3	hSpCas9	negative selection	8528586
63690355	63690378	17	+	27260156	RDES	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.16049000979738381	[319]	[295,336,361,316]	-3	hSpCas9	negative selection	8528587
63690315	63690338	17	-	27260156	PC3	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.432741822002495	[84]	[68,96,243,107]	8	hSpCas9	negative selection	8585578
63652553	63652576	17	+	27260156	PC3	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.030021265866539	[483]	[307,479,665,622]	0	hSpCas9	negative selection	8585579
63690325	63690348	17	+	27260156	PC3	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.048348197331632425	[269]	[159,241,608,182]	-1	hSpCas9	negative selection	8585580
63646043	63646066	17	+	27260156	PC3	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.21574641893486945	[283]	[125,247,428,276]	-5	hSpCas9	negative selection	8649836
63652635	63652658	17	+	27260156	PC3	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.16582709910677437	[573]	[278,420,1073,550]	-4	hSpCas9	negative selection	8649837
63690355	63690378	17	+	27260156	PC3	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.2194308019579702	[319]	[244,231,819,390]	5	hSpCas9	negative selection	8649838
63690315	63690338	17	-	27260156	PATU8988T	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.18790023076611684	[84]	[90,61,112,105]	3	hSpCas9	negative selection	8706829
63652553	63652576	17	+	27260156	PATU8988T	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.20941639634670853	[483]	[558,781,538,284]	3	hSpCas9	negative selection	8706830
63690325	63690348	17	+	27260156	PATU8988T	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	0.24106915016140118	[269]	[438,409,165,222]	4	hSpCas9	negative selection	8706831
63646043	63646066	17	+	27260156	PATU8988T	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.11060942932692452	[283]	[311,231,256,209]	-2	hSpCas9	negative selection	8771087
63652635	63652658	17	+	27260156	PATU8988T	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.23985766800784358	[573]	[609,695,657,659]	4	hSpCas9	negative selection	8771088
63690355	63690378	17	+	27260156	PATU8988T	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.2544203025364313	[319]	[218,378,549,321]	4	hSpCas9	negative selection	8771089
63690315	63690338	17	-	27260156	T47D	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.1887577313289479	[84]	[75,89,74,106]	-4	hSpCas9	negative selection	8828080
63652553	63652576	17	+	27260156	T47D	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.02270848471856357	[483]	[600,536,604,549]	0	hSpCas9	negative selection	8828081
63690325	63690348	17	+	27260156	T47D	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.15619245815392024	[269]	[253,283,293,296]	-3	hSpCas9	negative selection	8828082
63646043	63646066	17	+	27260156	T47D	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.0009694897648867551	[283]	[276,268,419,362]	0	hSpCas9	negative selection	8892338
63652635	63652658	17	+	27260156	T47D	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.21442530255400083	[573]	[774,710,717,909]	4	hSpCas9	negative selection	8892339
63690355	63690378	17	+	27260156	T47D	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.13985892603228556	[319]	[384,353,277,335]	-3	hSpCas9	negative selection	8892340
63690315	63690338	17	-	27260156	SU8686	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.08640941800512847	[84]	[87,68,62,148]	1	hSpCas9	negative selection	8949331
63652553	63652576	17	+	27260156	SU8686	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.006957072964299926	[483]	[400,444,495,619]	0	hSpCas9	negative selection	8949332
63690325	63690348	17	+	27260156	SU8686	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.12528898717580328	[269]	[208,238,243,301]	-2	hSpCas9	negative selection	8949333
63646043	63646066	17	+	27260156	SU8686	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.14683992395222056	[283]	[178,296,424,373]	2	hSpCas9	negative selection	9013589
63652635	63652658	17	+	27260156	SU8686	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.05654080262379074	[573]	[481,572,661,460]	-1	hSpCas9	negative selection	9013590
63690355	63690378	17	+	27260156	SU8686	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.22815372900560593	[319]	[207,299,292,286]	-4	hSpCas9	negative selection	9013591
63690315	63690338	17	-	27260156	SKES1	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.22067562966100462	[84]	[144,63,59,34]	-5	hSpCas9	negative selection	9070582
63652553	63652576	17	+	27260156	SKES1	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	0.09132079948968352	[483]	[578,427,504,535]	2	hSpCas9	negative selection	9070583
63690325	63690348	17	+	27260156	SKES1	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	0.1277981096967934	[269]	[236,360,237,333]	2	hSpCas9	negative selection	9070584
63646043	63646066	17	+	27260156	SKES1	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	-0.11045164245915717	[283]	[352,339,200,184]	-2	hSpCas9	negative selection	9134840
63652635	63652658	17	+	27260156	SKES1	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.09017150736321089	[573]	[695,617,429,445]	-2	hSpCas9	negative selection	9134841
63690355	63690378	17	+	27260156	SKES1	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.1334992177974757	[319]	[425,414,309,273]	3	hSpCas9	negative selection	9134842
63690315	63690338	17	-	27260156	TOV112D	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.04035148815202261	[84]	[65,63,72,137]	0	hSpCas9	negative selection	9191833
63652553	63652576	17	+	27260156	TOV112D	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.10487223751416107	[483]	[298,604,418,502]	-2	hSpCas9	negative selection	9191834
63690325	63690348	17	+	27260156	TOV112D	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.7186449637037653	[269]	[176,237,124,136]	-8	hSpCas9	negative selection	9191835
63646043	63646066	17	+	27260156	TOV112D	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.4203013565751161	[283]	[553,341,140,486]	7	hSpCas9	negative selection	9256091
63652635	63652658	17	+	27260156	TOV112D	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.08789811058703689	[573]	[598,860,449,593]	1	hSpCas9	negative selection	9256092
63690355	63690378	17	+	27260156	TOV112D	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	-0.09892670715009155	[319]	[379,452,247,163]	-2	hSpCas9	negative selection	9256093
63690315	63690338	17	-	27260156	TC71	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.007772441316261425	[84]	[107,59,71,128]	0	hSpCas9	negative selection	9313084
63652553	63652576	17	+	27260156	TC71	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.17229439098385935	[483]	[479,382,439,543]	-4	hSpCas9	negative selection	9313085
63690325	63690348	17	+	27260156	TC71	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	-0.05704252542631727	[269]	[366,242,239,260]	-1	hSpCas9	negative selection	9313086
63646043	63646066	17	+	27260156	TC71	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.19803841268662303	[283]	[406,363,266,360]	5	hSpCas9	negative selection	9377342
63652635	63652658	17	+	27260156	TC71	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	-0.06385941373376847	[573]	[597,594,531,633]	-2	hSpCas9	negative selection	9377343
63690355	63690378	17	+	27260156	TC71	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.06062282365835414	[319]	[346,330,393,357]	1	hSpCas9	negative selection	9377344
63690315	63690338	17	-	27260156	TC32	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.6261370946769182	[84]	[39,45,62,60]	-8	hSpCas9	negative selection	9434335
63652553	63652576	17	+	27260156	TC32	viability	TCAGAATTATAGCGTTCAGCCGG	MAP3K3	ENSG00000198909	-0.046303761273635294	[483]	[398,338,450,600]	-1	hSpCas9	negative selection	9434336
63690325	63690348	17	+	27260156	TC32	viability	GGTCTATTTGTGCTATGACGTGG	MAP3K3	ENSG00000198909	0.1024347891629297	[269]	[194,310,323,243]	1	hSpCas9	negative selection	9434337
63646043	63646066	17	+	27260156	TC32	viability	AGAATCAAGTTCGAGCACAACGG	MAP3K3	ENSG00000198909	0.10536270752949384	[283]	[275,206,419,282]	2	hSpCas9	negative selection	9498593
63652635	63652658	17	+	27260156	TC32	viability	TCTACATTACATGAACAATGAGG	MAP3K3	ENSG00000198909	0.18318083784924383	[573]	[613,563,648,606]	3	hSpCas9	negative selection	9498594
63690355	63690378	17	+	27260156	TC32	viability	ACGTGAACTTGCTTCCAAGCAGG	MAP3K3	ENSG00000198909	0.25412574506059565	[319]	[381,276,390,397]	4	hSpCas9	negative selection	9498595
63622758	63622781	17	-	27869803	HPAFII	viability after 27 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-0.42757940154953844	[516]	[206,197,NaN]	-3	hSpCas9	negative selection	9562303
63632667	63632690	17	+	27869803	HPAFII	viability after 27 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.9278219702448354	[542]	[595,498,NaN]	7	hSpCas9	negative selection	9562304
63646045	63646068	17	+	27869803	HPAFII	viability after 27 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.24900723633479616	[470]	[344,251,NaN]	2	hSpCas9	negative selection	9562305
63666983	63667006	17	+	27869803	HPAFII	viability after 27 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.46101580296398764	[307]	[187,58,NaN]	-3	hSpCas9	negative selection	9562306
63681796	63681819	17	-	27869803	HPAFII	viability after 27 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.8926965631768409	[626]	[164,187,NaN]	-6	hSpCas9	negative selection	9562307
63685557	63685580	17	+	27869803	HPAFII	viability after 27 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-1.3118854803196862	[169]	[77,0,NaN]	-7	hSpCas9	negative selection	9562308
63622758	63622781	17	-	27869803	HPAFII	viability after 15 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-0.8097843823435847	[516]	[369,283,NaN]	-7	hSpCas9	negative selection	9644752
63632667	63632690	17	+	27869803	HPAFII	viability after 15 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.8755578248200262	[542]	[1259,952,NaN]	8	hSpCas9	negative selection	9644753
63646045	63646068	17	+	27869803	HPAFII	viability after 15 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.2779068304487381	[470]	[472,382,NaN]	-3	hSpCas9	negative selection	9644754
63666983	63667006	17	+	27869803	HPAFII	viability after 15 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	0.09567058758070413	[307]	[653,166,NaN]	1	hSpCas9	negative selection	9644755
63681796	63681819	17	-	27869803	HPAFII	viability after 15 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.7150202492618629	[626]	[346,449,NaN]	-6	hSpCas9	negative selection	9644756
63685557	63685580	17	+	27869803	HPAFII	viability after 15 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	0.45137872584560557	[169]	[456,120,NaN]	5	hSpCas9	negative selection	9644757
63622758	63622781	17	-	27869803	ASPC1	viability after 36 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-0.4810844328558431	[1196]	[299,356,249]	-5	hSpCas9	negative selection	9727201
63632667	63632690	17	+	27869803	ASPC1	viability after 36 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.6372331574173047	[1604]	[916,940,774]	6	hSpCas9	negative selection	9727202
63646045	63646068	17	+	27869803	ASPC1	viability after 36 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.5961890230094171	[961]	[806,308,449]	6	hSpCas9	negative selection	9727203
63666983	63667006	17	+	27869803	ASPC1	viability after 36 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	0.5549114230546386	[774]	[941,175,186]	5	hSpCas9	negative selection	9727204
63681796	63681819	17	-	27869803	ASPC1	viability after 36 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.45620770399200816	[1328]	[358,453,227]	-4	hSpCas9	negative selection	9727205
63685557	63685580	17	+	27869803	ASPC1	viability after 36 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	0.6240012399200925	[479]	[61,362,309]	6	hSpCas9	negative selection	9727206
63622758	63622781	17	-	27869803	PATU8988S	viability after 35 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	0.4366601727391377	[1108]	[615,592,NaN]	5	hSpCas9	negative selection	9809650
63632667	63632690	17	+	27869803	PATU8988S	viability after 35 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.4542124129626446	[1627]	[1029,765,NaN]	5	hSpCas9	negative selection	9809651
63646045	63646068	17	+	27869803	PATU8988S	viability after 35 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	-0.14557744761846814	[974]	[350,358,NaN]	-1	hSpCas9	negative selection	9809652
63666983	63667006	17	+	27869803	PATU8988S	viability after 35 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.435367217214603	[711]	[237,185,NaN]	-4	hSpCas9	negative selection	9809653
63681796	63681819	17	-	27869803	PATU8988S	viability after 35 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.5049019958642926	[829]	[266,203,NaN]	-5	hSpCas9	negative selection	9809654
63685557	63685580	17	+	27869803	PATU8988S	viability after 35 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-1.1420152580829954	[473]	[87,84,NaN]	-8	hSpCas9	negative selection	9809655
63622758	63622781	17	-	27869803	PATU8988S	viability after 31 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	0.4786348788300574	[1108]	[525,730,NaN]	6	hSpCas9	negative selection	9892099
63632667	63632690	17	+	27869803	PATU8988S	viability after 31 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.36167012929865505	[1627]	[768,916,NaN]	4	hSpCas9	negative selection	9892100
63646045	63646068	17	+	27869803	PATU8988S	viability after 31 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.04939932394128499	[974]	[389,417,NaN]	0	hSpCas9	negative selection	9892101
63666983	63667006	17	+	27869803	PATU8988S	viability after 31 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.5048376652704083	[711]	[196,203,NaN]	-5	hSpCas9	negative selection	9892102
63681796	63681819	17	-	27869803	PATU8988S	viability after 31 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-0.010496851172103194	[829]	[317,341,NaN]	0	hSpCas9	negative selection	9892103
63685557	63685580	17	+	27869803	PATU8988S	viability after 31 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-0.9045829121294321	[473]	[118,77,NaN]	-7	hSpCas9	negative selection	9892104
63622758	63622781	17	-	27869803	HPAFII	viability after 35 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-0.37501957471808844	[516]	[190,213,NaN]	-2	hSpCas9	negative selection	9974548
63632667	63632690	17	+	27869803	HPAFII	viability after 35 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	0.8946828128974733	[542]	[551,464,NaN]	6	hSpCas9	negative selection	9974549
63646045	63646068	17	+	27869803	HPAFII	viability after 35 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.4425136962385816	[470]	[395,242,NaN]	3	hSpCas9	negative selection	9974550
63666983	63667006	17	+	27869803	HPAFII	viability after 35 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.18002154750700775	[307]	[107,170,NaN]	-1	hSpCas9	negative selection	9974551
63681796	63681819	17	-	27869803	HPAFII	viability after 35 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-1.244612068823025	[626]	[45,232,NaN]	-6	hSpCas9	negative selection	9974552
63685557	63685580	17	+	27869803	HPAFII	viability after 35 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-1.098405763984722	[169]	[74,0,NaN]	-6	hSpCas9	negative selection	9974553
63622758	63622781	17	-	27869803	HPAFII	viability after 31 days	GCGGTGGCGACACTTACCCATGG	MAP3K3	ENSG00000198909	-0.5787193409775018	[516]	[177,211,NaN]	-4	hSpCas9	negative selection	10056997
63632667	63632690	17	+	27869803	HPAFII	viability after 31 days	CTCTTTCATTGCAGACGAACAGG	MAP3K3	ENSG00000198909	1.1888090989766358	[542]	[620,774,NaN]	8	hSpCas9	negative selection	10056998
63646045	63646068	17	+	27869803	HPAFII	viability after 31 days	AATCAAGTTCGAGCACAACGGGG	MAP3K3	ENSG00000198909	0.15040763926456102	[470]	[312,271,NaN]	1	hSpCas9	negative selection	10056999
63666983	63667006	17	+	27869803	HPAFII	viability after 31 days	TCAAGGCTTCCCAGTCCGCAGGG	MAP3K3	ENSG00000198909	-0.20886233594986714	[307]	[228,62,NaN]	-1	hSpCas9	negative selection	10057000
63681796	63681819	17	-	27869803	HPAFII	viability after 31 days	CCGCTCAGGAACATAGCCAGGGG	MAP3K3	ENSG00000198909	-1.5898193134824872	[626]	[69,167,NaN]	-7	hSpCas9	negative selection	10057001
63685557	63685580	17	+	27869803	HPAFII	viability after 31 days	GAAGCTGCCAATCCTTGGACAGG	MAP3K3	ENSG00000198909	-1.742768189896139	[169]	[50,3,NaN]	-7	hSpCas9	negative selection	10057002
63666947	63666970	17	-	28162770	P31FUJ	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-0.6909084255851083	[135]	[98]	-5	hSpCas9	negative selection	10188804
63690315	63690338	17	-	28162770	P31FUJ	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.06715004945747718	[262]	[294]	0	hSpCas9	negative selection	10188805
63681797	63681820	17	-	28162770	P31FUJ	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-0.11333853781280712	[138]	[150]	-1	hSpCas9	negative selection	10188806
63689592	63689615	17	-	28162770	P31FUJ	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-2.512910123607114	[169]	[34]	-8	hSpCas9	negative selection	10188807
63691792	63691815	17	+	28162770	P31FUJ	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	0.22883570772660455	[296]	[408]	2	hSpCas9	negative selection	10188808
63692312	63692335	17	+	28162770	P31FUJ	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	-0.43096851007093795	[373]	[325]	-4	hSpCas9	negative selection	10188809
63666984	63667007	17	+	28162770	P31FUJ	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.05344862282437335	[626]	[709]	0	hSpCas9	negative selection	10188810
63681776	63681799	17	-	28162770	P31FUJ	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	1.4286123567446507	[97]	[309]	9	hSpCas9	negative selection	10188811
63685548	63685571	17	-	28162770	P31FUJ	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.23090914160015497	[458]	[632]	2	hSpCas9	negative selection	10188812
63688838	63688861	17	-	28162770	P31FUJ	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	0.10823471342068824	[29]	[37]	1	hSpCas9	negative selection	10188813
63666947	63666970	17	-	28162770	TF1	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10358170
63690315	63690338	17	-	28162770	TF1	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	NaN	[NaN]	[205]	1	hSpCas9	negative selection	10358171
63681797	63681820	17	-	28162770	TF1	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10358172
63689592	63689615	17	-	28162770	TF1	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10358173
63691792	63691815	17	+	28162770	TF1	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	NaN	[NaN]	[264]	1	hSpCas9	negative selection	10358174
63692312	63692335	17	+	28162770	TF1	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	NaN	[NaN]	[226]	1	hSpCas9	negative selection	10358175
63666984	63667007	17	+	28162770	TF1	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	NaN	[NaN]	[432]	1	hSpCas9	negative selection	10358176
63681776	63681799	17	-	28162770	TF1	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	NaN	[NaN]	[175]	1	hSpCas9	negative selection	10358177
63685548	63685571	17	-	28162770	TF1	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	NaN	[NaN]	[531]	1	hSpCas9	negative selection	10358178
63688838	63688861	17	-	28162770	TF1	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10358179
63666947	63666970	17	-	28162770	SKM1	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-0.7532889479379911	[40]	[42]	-5	hSpCas9	negative selection	10527536
63690315	63690338	17	-	28162770	SKM1	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.2604604621699673	[50]	[107]	2	hSpCas9	negative selection	10527537
63681797	63681820	17	-	28162770	SKM1	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-0.5418937788292703	[41]	[50]	-4	hSpCas9	negative selection	10527538
63689592	63689615	17	-	28162770	SKM1	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-1.576889200185474	[53]	[31]	-8	hSpCas9	negative selection	10527539
63691792	63691815	17	+	28162770	SKM1	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	-0.10645508749070498	[94]	[155]	-1	hSpCas9	negative selection	10527540
63692312	63692335	17	+	28162770	SKM1	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	0.13825212318523827	[91]	[178]	1	hSpCas9	negative selection	10527541
63666984	63667007	17	+	28162770	SKM1	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.8626436825193515	[143]	[139]	-6	hSpCas9	negative selection	10527542
63681776	63681799	17	-	28162770	SKM1	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	-0.12156197988091333	[23]	[38]	-1	hSpCas9	negative selection	10527543
63685548	63685571	17	-	28162770	SKM1	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.34655257168689224	[116]	[262]	3	hSpCas9	negative selection	10527544
63688838	63688861	17	-	28162770	SKM1	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	0.8478497002856638	[10]	[34]	7	hSpCas9	negative selection	10527545
63666947	63666970	17	-	28162770	SKM1	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-0.7532889479379911	[40]	[42]	-5	hSpCas9	negative selection	10696902
63690315	63690338	17	-	28162770	SKM1	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.2604604621699673	[50]	[107]	2	hSpCas9	negative selection	10696903
63681797	63681820	17	-	28162770	SKM1	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-0.5418937788292703	[41]	[50]	-4	hSpCas9	negative selection	10696904
63689592	63689615	17	-	28162770	SKM1	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-1.576889200185474	[53]	[31]	-8	hSpCas9	negative selection	10696905
63691792	63691815	17	+	28162770	SKM1	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	-0.10645508749070498	[94]	[155]	-1	hSpCas9	negative selection	10696906
63692312	63692335	17	+	28162770	SKM1	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	0.13825212318523827	[91]	[178]	1	hSpCas9	negative selection	10696907
63666984	63667007	17	+	28162770	SKM1	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.8626436825193515	[143]	[139]	-6	hSpCas9	negative selection	10696908
63681776	63681799	17	-	28162770	SKM1	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	-0.12156197988091333	[23]	[38]	-1	hSpCas9	negative selection	10696909
63685548	63685571	17	-	28162770	SKM1	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.34655257168689224	[116]	[262]	3	hSpCas9	negative selection	10696910
63688838	63688861	17	-	28162770	SKM1	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	0.8478497002856638	[10]	[34]	7	hSpCas9	negative selection	10696911
63666947	63666970	17	-	28162770	PL21	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-0.43457592142893553	[117]	[37]	-3	hSpCas9	negative selection	10866268
63690315	63690338	17	-	28162770	PL21	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.39209088669587544	[198]	[65]	-3	hSpCas9	negative selection	10866269
63681797	63681820	17	-	28162770	PL21	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	1.1653741963286435	[125]	[122]	8	hSpCas9	negative selection	10866270
63689592	63689615	17	-	28162770	PL21	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-0.2630344058337938	[192]	[69]	-2	hSpCas9	negative selection	10866271
63691792	63691815	17	+	28162770	PL21	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	-1.0374392106618038	[381]	[80]	-6	hSpCas9	negative selection	10866272
63692312	63692335	17	+	28162770	PL21	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	-0.025928464990526034	[392]	[167]	0	hSpCas9	negative selection	10866273
63666984	63667007	17	+	28162770	PL21	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.10949520420661296	[408]	[164]	-1	hSpCas9	negative selection	10866274
63681776	63681799	17	-	28162770	PL21	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	1.817523592902854	[87]	[134]	9	hSpCas9	negative selection	10866275
63685548	63685571	17	-	28162770	PL21	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.15926733307379215	[357]	[173]	1	hSpCas9	negative selection	10866276
63688838	63688861	17	-	28162770	PL21	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	0.5220677093766821	[15]	[9]	4	hSpCas9	negative selection	10866277
63666947	63666970	17	-	28162770	P31FUJ	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-0.6909084255851083	[135]	[98]	-5	hSpCas9	negative selection	11035634
63690315	63690338	17	-	28162770	P31FUJ	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.06715004945747718	[262]	[294]	0	hSpCas9	negative selection	11035635
63681797	63681820	17	-	28162770	P31FUJ	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-0.11333853781280712	[138]	[150]	-1	hSpCas9	negative selection	11035636
63689592	63689615	17	-	28162770	P31FUJ	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-2.512910123607114	[169]	[34]	-8	hSpCas9	negative selection	11035637
63691792	63691815	17	+	28162770	P31FUJ	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	0.22883570772660455	[296]	[408]	2	hSpCas9	negative selection	11035638
63692312	63692335	17	+	28162770	P31FUJ	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	-0.43096851007093795	[373]	[325]	-4	hSpCas9	negative selection	11035639
63666984	63667007	17	+	28162770	P31FUJ	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.05344862282437335	[626]	[709]	0	hSpCas9	negative selection	11035640
63681776	63681799	17	-	28162770	P31FUJ	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	1.4286123567446507	[97]	[309]	9	hSpCas9	negative selection	11035641
63685548	63685571	17	-	28162770	P31FUJ	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.23090914160015497	[458]	[632]	2	hSpCas9	negative selection	11035642
63688838	63688861	17	-	28162770	P31FUJ	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	0.10823471342068824	[29]	[37]	1	hSpCas9	negative selection	11035643
63666947	63666970	17	-	28162770	OCIAML5	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-0.736589353444061	[59]	[64]	-5	hSpCas9	negative selection	11205000
63690315	63690338	17	-	28162770	OCIAML5	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.9063123298180615	[106]	[361]	7	hSpCas9	negative selection	11205001
63681797	63681820	17	-	28162770	OCIAML5	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-0.5186428371388051	[99]	[125]	-4	hSpCas9	negative selection	11205002
63689592	63689615	17	-	28162770	OCIAML5	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-2.1058231631097803	[61]	[25]	-8	hSpCas9	negative selection	11205003
63691792	63691815	17	+	28162770	OCIAML5	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	0.21523181842484296	[177]	[372]	1	hSpCas9	negative selection	11205004
63692312	63692335	17	+	28162770	OCIAML5	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	1.4672360546165422	[109]	[548]	9	hSpCas9	negative selection	11205005
63666984	63667007	17	+	28162770	OCIAML5	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.013460714821953212	[273]	[489]	0	hSpCas9	negative selection	11205006
63681776	63681799	17	-	28162770	OCIAML5	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	1.0548240247445215	[35]	[134]	8	hSpCas9	negative selection	11205007
63685548	63685571	17	-	28162770	OCIAML5	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.3510252945135147	[214]	[494]	3	hSpCas9	negative selection	11205008
63688838	63688861	17	-	28162770	OCIAML5	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	-1.5110296530289298	[29]	[18]	-7	hSpCas9	negative selection	11205009
63666947	63666970	17	-	28162770	EOL1	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-1.114980592616103	[221]	[53]	-6	hSpCas9	negative selection	11374366
63690315	63690338	17	-	28162770	EOL1	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.25575368004590765	[247]	[155]	2	hSpCas9	negative selection	11374367
63681797	63681820	17	-	28162770	EOL1	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-1.0754522284294656	[303]	[75]	-6	hSpCas9	negative selection	11374368
63689592	63689615	17	-	28162770	EOL1	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-0.5258102634413008	[316]	[115]	-4	hSpCas9	negative selection	11374369
63691792	63691815	17	+	28162770	EOL1	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	-0.32831700199018343	[621]	[260]	-2	hSpCas9	negative selection	11374370
63692312	63692335	17	+	28162770	EOL1	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	0.3308283696640162	[660]	[437]	3	hSpCas9	negative selection	11374371
63666984	63667007	17	+	28162770	EOL1	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.003980473296427367	[570]	[299]	0	hSpCas9	negative selection	11374372
63681776	63681799	17	-	28162770	EOL1	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	0.048283139992779445	[133]	[72]	0	hSpCas9	negative selection	11374373
63685548	63685571	17	-	28162770	EOL1	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	-0.5699241952027142	[447]	[158]	-4	hSpCas9	negative selection	11374374
63688838	63688861	17	-	28162770	EOL1	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	2.9245477715705346	[24]	[99]	9	hSpCas9	negative selection	11374375
63666947	63666970	17	-	28162770	MOLM13	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-1.4877164990969678	[127]	[32]	-6	hSpCas9	negative selection	11543732
63690315	63690338	17	-	28162770	MOLM13	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.08798541939472496	[310]	[238]	0	hSpCas9	negative selection	11543733
63681797	63681820	17	-	28162770	MOLM13	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-0.06726956325596353	[241]	[166]	0	hSpCas9	negative selection	11543734
63689592	63689615	17	-	28162770	MOLM13	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-2.5119327365177906	[212]	[26]	-8	hSpCas9	negative selection	11543735
63691792	63691815	17	+	28162770	MOLM13	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	0.06983021744124562	[534]	[405]	0	hSpCas9	negative selection	11543736
63692312	63692335	17	+	28162770	MOLM13	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	0.17973829864164093	[590]	[483]	1	hSpCas9	negative selection	11543737
63666984	63667007	17	+	28162770	MOLM13	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.3488360633540891	[501]	[284]	-2	hSpCas9	negative selection	11543738
63681776	63681799	17	-	28162770	MOLM13	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	0.1741581784878683	[75]	[61]	1	hSpCas9	negative selection	11543739
63685548	63685571	17	-	28162770	MOLM13	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.9541102071062922	[518]	[726]	7	hSpCas9	negative selection	11543740
63688838	63688861	17	-	28162770	MOLM13	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	-4.924428041234182	[41]	[0]	-9	hSpCas9	negative selection	11543741
63666947	63666970	17	-	28162770	HEL	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-0.7926473126702893	[118]	[43]	-5	hSpCas9	negative selection	11713098
63690315	63690338	17	-	28162770	HEL	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.8899937099482415	[216]	[74]	-5	hSpCas9	negative selection	11713099
63681797	63681820	17	-	28162770	HEL	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-0.06846366610076754	[184]	[112]	0	hSpCas9	negative selection	11713100
63689592	63689615	17	-	28162770	HEL	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-1.984043844415426	[209]	[33]	-8	hSpCas9	negative selection	11713101
63691792	63691815	17	+	28162770	HEL	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	0.08447912481867292	[454]	[308]	0	hSpCas9	negative selection	11713102
63692312	63692335	17	+	28162770	HEL	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	0.7167394134441337	[436]	[459]	6	hSpCas9	negative selection	11713103
63666984	63667007	17	+	28162770	HEL	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	0.10850713340013052	[474]	[327]	0	hSpCas9	negative selection	11713104
63681776	63681799	17	-	28162770	HEL	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	0.04128820849063186	[87]	[57]	0	hSpCas9	negative selection	11713105
63685548	63685571	17	-	28162770	HEL	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	-0.027741739906856244	[416]	[261]	0	hSpCas9	negative selection	11713106
63688838	63688861	17	-	28162770	HEL	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	0.3532322148053719	[10]	[8]	3	hSpCas9	negative selection	11713107
63666947	63666970	17	-	28162770	MV411	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-0.1471937378342315	[116]	[88]	-1	hSpCas9	negative selection	11882464
63690315	63690338	17	-	28162770	MV411	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.26451106414171677	[167]	[169]	2	hSpCas9	negative selection	11882465
63681797	63681820	17	-	28162770	MV411	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	0.4576552581731208	[101]	[117]	4	hSpCas9	negative selection	11882466
63689592	63689615	17	-	28162770	MV411	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-3.4687694832166334	[183]	[13]	-9	hSpCas9	negative selection	11882467
63691792	63691815	17	+	28162770	MV411	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	-0.08334146168685264	[326]	[259]	0	hSpCas9	negative selection	11882468
63692312	63692335	17	+	28162770	MV411	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	-0.17251543891018517	[391]	[292]	-1	hSpCas9	negative selection	11882469
63666984	63667007	17	+	28162770	MV411	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	0.2586068585008867	[385]	[388]	2	hSpCas9	negative selection	11882470
63681776	63681799	17	-	28162770	MV411	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	1.930963885987521	[65]	[211]	9	hSpCas9	negative selection	11882471
63685548	63685571	17	-	28162770	MV411	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	-0.217640630995664	[351]	[254]	-2	hSpCas9	negative selection	11882472
63688838	63688861	17	-	28162770	MV411	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	0.662475050061619	[11]	[15]	6	hSpCas9	negative selection	11882473
63666947	63666970	17	-	28162770	MONOMAC1	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-0.23551099487418947	[75]	[73]	-2	hSpCas9	negative selection	12051830
63690315	63690338	17	-	28162770	MONOMAC1	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	0.1414877583585034	[120]	[152]	1	hSpCas9	negative selection	12051831
63681797	63681820	17	-	28162770	MONOMAC1	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	-0.07999742586933445	[70]	[76]	0	hSpCas9	negative selection	12051832
63689592	63689615	17	-	28162770	MONOMAC1	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-3.551879564419651	[132]	[12]	-9	hSpCas9	negative selection	12051833
63691792	63691815	17	+	28162770	MONOMAC1	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	0.18693859592842532	[222]	[290]	2	hSpCas9	negative selection	12051834
63692312	63692335	17	+	28162770	MONOMAC1	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	-0.5667313608776433	[260]	[201]	-5	hSpCas9	negative selection	12051835
63666984	63667007	17	+	28162770	MONOMAC1	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.7079987663369329	[341]	[239]	-5	hSpCas9	negative selection	12051836
63681776	63681799	17	-	28162770	MONOMAC1	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	-0.4600712528933475	[47]	[39]	-4	hSpCas9	negative selection	12051837
63685548	63685571	17	-	28162770	MONOMAC1	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.33154318376408365	[286]	[413]	3	hSpCas9	negative selection	12051838
63688838	63688861	17	-	28162770	MONOMAC1	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	0.2390622677471197	[16]	[22]	2	hSpCas9	negative selection	12051839
63666947	63666970	17	-	28162770	OCIAML2	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	0.2867998714837605	[20]	[141]	2	hSpCas9	negative selection	12221196
63690315	63690338	17	-	28162770	OCIAML2	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.13878626148971618	[28]	[145]	-1	hSpCas9	negative selection	12221197
63681797	63681820	17	-	28162770	OCIAML2	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	0.225693784426699	[26]	[174]	2	hSpCas9	negative selection	12221198
63689592	63689615	17	-	28162770	OCIAML2	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-2.537744021100698	[43]	[41]	-8	hSpCas9	negative selection	12221199
63691792	63691815	17	+	28162770	OCIAML2	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	-0.34009826209993577	[65]	[288]	-3	hSpCas9	negative selection	12221200
63692312	63692335	17	+	28162770	OCIAML2	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	0.6578447327066479	[50]	[445]	6	hSpCas9	negative selection	12221201
63666984	63667007	17	+	28162770	OCIAML2	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	0.10550882509198889	[81]	[488]	1	hSpCas9	negative selection	12221202
63681776	63681799	17	-	28162770	OCIAML2	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	-0.5580926664925008	[16]	[63]	-4	hSpCas9	negative selection	12221203
63685548	63685571	17	-	28162770	OCIAML2	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.6517668061175654	[71]	[626]	6	hSpCas9	negative selection	12221204
63688838	63688861	17	-	28162770	OCIAML2	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	1.1538610396656321	[2]	[36]	9	hSpCas9	negative selection	12221205
63666947	63666970	17	-	28162770	OCIAML3	viability	GGACACCCCAGAGTGGGGAGAGG	MAP3K3	ENSG00000198909	-1.4279976888852342	[40]	[45]	-7	hSpCas9	negative selection	12390562
63690315	63690338	17	-	28162770	OCIAML3	viability	GCACAAATAGACCCTGCCGAAGG	MAP3K3	ENSG00000198909	-0.8184392069342097	[58]	[100]	-6	hSpCas9	negative selection	12390563
63681797	63681820	17	-	28162770	OCIAML3	viability	GCCGCTCAGGAACATAGCCAGGG	MAP3K3	ENSG00000198909	0.21334728173344109	[27]	[97]	2	hSpCas9	negative selection	12390564
63689592	63689615	17	-	28162770	OCIAML3	viability	GGAGCGGCTGGAGGGCACCAGGG	MAP3K3	ENSG00000198909	-2.306725688243692	[58]	[35]	-9	hSpCas9	negative selection	12390565
63691792	63691815	17	+	28162770	OCIAML3	viability	GTACACGCGGCAGATCCTGGAGG	MAP3K3	ENSG00000198909	-0.3359394873837188	[96]	[231]	-3	hSpCas9	negative selection	12390566
63692312	63692335	17	+	28162770	OCIAML3	viability	GACGATCTGTATGTCGGGGACGG	MAP3K3	ENSG00000198909	-0.35995230146213525	[87]	[206]	-3	hSpCas9	negative selection	12390567
63666984	63667007	17	+	28162770	OCIAML3	viability	CAAGGCTTCCCAGTCCGCAGGGG	MAP3K3	ENSG00000198909	-0.03231491892585425	[124]	[368]	0	hSpCas9	negative selection	12390568
63681776	63681799	17	-	28162770	OCIAML3	viability	GGGGAGGTGAGCTTCGGCCAGGG	MAP3K3	ENSG00000198909	-0.2858853449618315	[20]	[51]	-2	hSpCas9	negative selection	12390569
63685548	63685571	17	-	28162770	OCIAML3	viability	GGATTGGCAGCTTCCAGACAAGG	MAP3K3	ENSG00000198909	0.1835999383393888	[90]	[311]	1	hSpCas9	negative selection	12390570
63688838	63688861	17	-	28162770	OCIAML3	viability	GCACAGACACGTGGTAGCGCCGG	MAP3K3	ENSG00000198909	0.7564896067599698	[9]	[50]	6	hSpCas9	negative selection	12390571