Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4216
• Symbol:MAP3K4
• Description:mitogen-activated protein kinase kinase kinase 4

DataSource: http://genomecrispr.dkfz.de/#!/results/MAP3K4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
160992034	160992057	6	-	26472758	Jiyoye	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.2137695890502611	[270]	[236]	1	hSpCas9	negative selection	96023
160991962	160991985	6	-	26472758	Jiyoye	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	0.6522878793424047	[26]	[31]	5	hSpCas9	negative selection	96024
161073478	161073501	6	+	26472758	Jiyoye	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.3912338376368518	[90]	[89]	3	hSpCas9	negative selection	96025
161080989	161081012	6	+	26472758	Jiyoye	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.8641266403115209	[209]	[86]	-6	hSpCas9	negative selection	96026
161097141	161097164	6	-	26472758	Jiyoye	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	0.9119675335430462	[73]	[104]	6	hSpCas9	negative selection	96027
161101961	161101984	6	+	26472758	Jiyoye	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	-0.31954011596657567	[186]	[112]	-2	hSpCas9	negative selection	96028
161102695	161102718	6	+	26472758	Jiyoye	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	-0.5195079408512058	[210]	[110]	-4	hSpCas9	negative selection	96029
161109898	161109921	6	-	26472758	Jiyoye	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	0.10865189095345477	[106]	[86]	0	hSpCas9	negative selection	96030
161111929	161111952	6	+	26472758	Jiyoye	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.4886357682221554	[226]	[121]	-4	hSpCas9	negative selection	96031
161115244	161115267	6	+	26472758	Jiyoye	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	-0.4264662320720067	[179]	[100]	-3	hSpCas9	negative selection	96032
160992034	160992057	6	-	26472758	KBM7	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.7187577276419945	[867,393]	[454,486]	7	hSpCas9	negative selection	287141
160991962	160991985	6	-	26472758	KBM7	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	1.124111527109589	[458,348]	[300,507]	9	hSpCas9	negative selection	287142
161073478	161073501	6	+	26472758	KBM7	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.18507697204965226	[412,310]	[216,168]	2	hSpCas9	negative selection	287143
161080989	161081012	6	+	26472758	KBM7	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.1320611729252041	[461,354]	[308,118]	1	hSpCas9	negative selection	287144
161097141	161097164	6	-	26472758	KBM7	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	0.5342655522188737	[715,314]	[465,224]	6	hSpCas9	negative selection	287145
161101961	161101984	6	+	26472758	KBM7	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	-0.1445908752417348	[479,334]	[198,145]	-1	hSpCas9	negative selection	287146
161102695	161102718	6	+	26472758	KBM7	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	-0.4663604461433239	[563,375]	[129,181]	-4	hSpCas9	negative selection	287147
161109898	161109921	6	-	26472758	KBM7	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	1.1849210459456208	[441,417]	[543,385]	9	hSpCas9	negative selection	287148
161111929	161111952	6	+	26472758	KBM7	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	0.5853301535176593	[795,732]	[677,415]	6	hSpCas9	negative selection	287149
161115244	161115267	6	+	26472758	KBM7	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	0.6239049011351575	[563,666]	[480,425]	6	hSpCas9	negative selection	287150
160992034	160992057	6	-	26472758	Raji	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.03462719293828531	[365]	[86]	0	hSpCas9	negative selection	478259
160991962	160991985	6	-	26472758	Raji	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	-0.1320823993217899	[169]	[35]	-1	hSpCas9	negative selection	478260
161073478	161073501	6	+	26472758	Raji	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.1880723481525718	[161]	[32]	-1	hSpCas9	negative selection	478261
161080989	161081012	6	+	26472758	Raji	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-1.3972368570299531	[226]	[19]	-7	hSpCas9	negative selection	478262
161097141	161097164	6	-	26472758	Raji	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	-0.7959404452147267	[201]	[26]	-6	hSpCas9	negative selection	478263
161101961	161101984	6	+	26472758	Raji	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	0.35105261634046225	[249]	[73]	3	hSpCas9	negative selection	478264
161102695	161102718	6	+	26472758	Raji	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.7227196851382746	[234]	[89]	6	hSpCas9	negative selection	478265
161109898	161109921	6	-	26472758	Raji	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	-1.1002118840347679	[193]	[20]	-7	hSpCas9	negative selection	478266
161111929	161111952	6	+	26472758	Raji	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-1.041008304519072	[531]	[59]	-6	hSpCas9	negative selection	478267
161115244	161115267	6	+	26472758	Raji	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	0.10738353537359929	[239]	[59]	1	hSpCas9	negative selection	478268
160992034	160992057	6	-	26472758	K562	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	-0.09693989716981699	[597]	[471]	0	hSpCas9	negative selection	669377
160991962	160991985	6	-	26472758	K562	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	-1.0514056132850162	[355]	[144]	-5	hSpCas9	negative selection	669378
161073478	161073501	6	+	26472758	K562	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.5424073810264838	[313]	[181]	-3	hSpCas9	negative selection	669379
161080989	161081012	6	+	26472758	K562	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.41469599258038814	[454]	[511]	3	hSpCas9	negative selection	669380
161097141	161097164	6	-	26472758	K562	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	0.5080070575004758	[433]	[520]	4	hSpCas9	negative selection	669381
161101961	161101984	6	+	26472758	K562	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	-0.0784489276845299	[383]	[306]	0	hSpCas9	negative selection	669382
161102695	161102718	6	+	26472758	K562	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.3774636634076125	[382]	[419]	3	hSpCas9	negative selection	669383
161109898	161109921	6	-	26472758	K562	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	0.2585860595930407	[303]	[306]	2	hSpCas9	negative selection	669384
161111929	161111952	6	+	26472758	K562	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.5949831593557796	[568]	[317]	-4	hSpCas9	negative selection	669385
161115244	161115267	6	+	26472758	K562	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	0.07868152318756805	[515]	[459]	0	hSpCas9	negative selection	669386
160991965	160991988	6	-	26627737	DLD1	viability	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	-0.07050904453231224	[546]	[138,160,184]	0	hSpCas9	negative selection	831199
161034244	161034267	6	+	26627737	DLD1	viability	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.3445404048925842	[813]	[332,342,297]	3	hSpCas9	negative selection	831204
161049724	161049747	6	-	26627737	DLD1	viability	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.5440461109682853	[1044]	[380,457,573]	5	hSpCas9	negative selection	831205
161070744	161070767	6	-	26627737	DLD1	viability	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	-0.4005277990056062	[187]	[47,55,31]	-4	hSpCas9	negative selection	831206
161073478	161073501	6	+	26627737	DLD1	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.6107449002954888	[355]	[177,65,248]	6	hSpCas9	negative selection	831207
161086360	161086383	6	+	26627737	DLD1	viability	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	-0.5730523857990024	[352]	[88,111,29]	-5	hSpCas9	negative selection	831208
160991965	160991988	6	-	26627737	GBM cells	viability after 5 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.7868035085641483	[106]	[94,102]	9	hSpCas9	negative selection	913514
161034244	161034267	6	+	26627737	GBM cells	viability after 5 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.0918898082453985	[544]	[290,331]	1	hSpCas9	negative selection	913519
161049724	161049747	6	-	26627737	GBM cells	viability after 5 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.5423132023435437	[378]	[301,289]	7	hSpCas9	negative selection	913520
161070744	161070767	6	-	26627737	GBM cells	viability after 5 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	0.4167621797483049	[131]	[81,106]	6	hSpCas9	negative selection	913521
161073478	161073501	6	+	26627737	GBM cells	viability after 5 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.6781764899139368	[362]	[332,289]	8	hSpCas9	negative selection	913522
161086360	161086383	6	+	26627737	GBM cells	viability after 5 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	0.5749694343998187	[178]	[123,161]	8	hSpCas9	negative selection	913523
160991965	160991988	6	-	26627737	GBM cells	viability after 13 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.2762699862746556	[106]	[66,72]	3	hSpCas9	negative selection	995829
161034244	161034267	6	+	26627737	GBM cells	viability after 13 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.2916021398648274	[544]	[383,343]	4	hSpCas9	negative selection	995834
161049724	161049747	6	-	26627737	GBM cells	viability after 13 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.7772275636633414	[378]	[379,329]	8	hSpCas9	negative selection	995835
161070744	161070767	6	-	26627737	GBM cells	viability after 13 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	0.9003107420511242	[131]	[179,95]	9	hSpCas9	negative selection	995836
161073478	161073501	6	+	26627737	GBM cells	viability after 13 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.9481609095692775	[362]	[545,244]	9	hSpCas9	negative selection	995837
161086360	161086383	6	+	26627737	GBM cells	viability after 13 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	0.01688877239882186	[178]	[73,117]	0	hSpCas9	negative selection	995838
160991965	160991988	6	-	26627737	GBM cells	viability after 21 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.46828860925737537	[106]	[93,67]	5	hSpCas9	negative selection	1078144
161034244	161034267	6	+	26627737	GBM cells	viability after 21 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.5759910652320444	[544]	[455,427]	6	hSpCas9	negative selection	1078149
161049724	161049747	6	-	26627737	GBM cells	viability after 21 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	1.4021429515251014	[378]	[574,515]	9	hSpCas9	negative selection	1078150
161070744	161070767	6	-	26627737	GBM cells	viability after 21 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	0.9898696384465342	[131]	[155,129]	8	hSpCas9	negative selection	1078151
161073478	161073501	6	+	26627737	GBM cells	viability after 21 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	1.001507544138983	[362]	[433,358]	8	hSpCas9	negative selection	1078152
161086360	161086383	6	+	26627737	GBM cells	viability after 21 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	1.1616575705127845	[178]	[227,207]	9	hSpCas9	negative selection	1078153
160991965	160991988	6	-	26627737	RPE1	viability after 9 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.8714455101379803	[822]	[442,507]	5	hSpCas9	negative selection	1160459
161034244	161034267	6	+	26627737	RPE1	viability after 9 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.6176522702946506	[952]	[507,392]	4	hSpCas9	negative selection	1160464
161049724	161049747	6	-	26627737	RPE1	viability after 9 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.5064220157072005	[1454]	[371,1001]	3	hSpCas9	negative selection	1160465
161070744	161070767	6	-	26627737	RPE1	viability after 9 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	1.3422325798730022	[276]	[218,220]	7	hSpCas9	negative selection	1160466
161073478	161073501	6	+	26627737	RPE1	viability after 9 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	1.3893779395973573	[670]	[238,951]	7	hSpCas9	negative selection	1160467
161086360	161086383	6	+	26627737	RPE1	viability after 9 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	2.699717166886333	[109]	[183,274]	9	hSpCas9	negative selection	1160468
160991965	160991988	6	-	26627737	RPE1	viability after 12 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.9307027147358833	[822]	[335,511]	6	hSpCas9	negative selection	1242774
161034244	161034267	6	+	26627737	RPE1	viability after 12 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.8831205296832888	[952]	[547,391]	5	hSpCas9	negative selection	1242779
161049724	161049747	6	-	26627737	RPE1	viability after 12 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.9082701751397358	[1454]	[534,943]	5	hSpCas9	negative selection	1242780
161070744	161070767	6	-	26627737	RPE1	viability after 12 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	1.4572172498623008	[276]	[215,191]	7	hSpCas9	negative selection	1242781
161073478	161073501	6	+	26627737	RPE1	viability after 12 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	1.4398859708308638	[670]	[287,701]	7	hSpCas9	negative selection	1242782
161086360	161086383	6	+	26627737	RPE1	viability after 12 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	2.437194949278018	[109]	[144,175]	9	hSpCas9	negative selection	1242783
160991965	160991988	6	-	26627737	RPE1	viability after 15 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	1.0025725884955905	[822]	[384,544]	6	hSpCas9	negative selection	1325089
161034244	161034267	6	+	26627737	RPE1	viability after 15 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	1.224899054036968	[952]	[763,500]	7	hSpCas9	negative selection	1325094
161049724	161049747	6	-	26627737	RPE1	viability after 15 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.9568949972312383	[1454]	[548,1039]	6	hSpCas9	negative selection	1325095
161070744	161070767	6	-	26627737	RPE1	viability after 15 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	1.5328142952634112	[276]	[213,238]	7	hSpCas9	negative selection	1325096
161073478	161073501	6	+	26627737	RPE1	viability after 15 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	1.737156821871251	[670]	[475,783]	8	hSpCas9	negative selection	1325097
161086360	161086383	6	+	26627737	RPE1	viability after 15 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	2.1120699163608094	[109]	[48,216]	9	hSpCas9	negative selection	1325098
160991965	160991988	6	-	26627737	RPE1	viability after 18 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	1.2516298869129443	[822]	[436,626]	7	hSpCas9	negative selection	1407404
161034244	161034267	6	+	26627737	RPE1	viability after 18 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	1.2842937231560887	[952]	[681,566]	7	hSpCas9	negative selection	1407409
161049724	161049747	6	-	26627737	RPE1	viability after 18 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	1.0009023224294453	[1454]	[517,1071]	6	hSpCas9	negative selection	1407410
161070744	161070767	6	-	26627737	RPE1	viability after 18 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	1.996928996070989	[276]	[323,270]	8	hSpCas9	negative selection	1407411
161073478	161073501	6	+	26627737	RPE1	viability after 18 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	2.0633235960471463	[670]	[372,1166]	8	hSpCas9	negative selection	1407412
161086360	161086383	6	+	26627737	RPE1	viability after 18 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	2.624195187444956	[109]	[241,119]	9	hSpCas9	negative selection	1407413
160991965	160991988	6	-	26627737	HeLa	viability after 8 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.3766495567814847	[561]	[587,194,234]	3	hSpCas9	negative selection	1489719
161034244	161034267	6	+	26627737	HeLa	viability after 8 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.19340504892446375	[559]	[262,372,201]	1	hSpCas9	negative selection	1489724
161049724	161049747	6	-	26627737	HeLa	viability after 8 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.4580289030315816	[632]	[471,383,304]	4	hSpCas9	negative selection	1489725
161070744	161070767	6	-	26627737	HeLa	viability after 8 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	-0.0010478663017245426	[305]	[206,142,69]	0	hSpCas9	negative selection	1489726
161073478	161073501	6	+	26627737	HeLa	viability after 8 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.07065770163075602	[583]	[253,205,332]	0	hSpCas9	negative selection	1489727
161086360	161086383	6	+	26627737	HeLa	viability after 8 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	-1.3447063934863546	[568]	[144,120,40]	-8	hSpCas9	negative selection	1489728
160991965	160991988	6	-	26627737	HeLa	viability after 12 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	-0.028178968463484222	[561]	[99,336,230]	0	hSpCas9	negative selection	1572034
161034244	161034267	6	+	26627737	HeLa	viability after 12 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	1.1183984796188078	[559]	[768,238,534]	7	hSpCas9	negative selection	1572039
161049724	161049747	6	-	26627737	HeLa	viability after 12 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.23232225451713284	[632]	[320,347,248]	2	hSpCas9	negative selection	1572040
161070744	161070767	6	-	26627737	HeLa	viability after 12 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	-0.9762172669809646	[305]	[62,52,77]	-7	hSpCas9	negative selection	1572041
161073478	161073501	6	+	26627737	HeLa	viability after 12 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.04745356039261894	[583]	[407,115,242]	0	hSpCas9	negative selection	1572042
161086360	161086383	6	+	26627737	HeLa	viability after 12 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	-0.9444844148467165	[568]	[73,151,135]	-7	hSpCas9	negative selection	1572043
160991965	160991988	6	-	26627737	HeLa	viability after 15 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	-0.4405602190949386	[561]	[157,177,169]	-4	hSpCas9	negative selection	1654349
161034244	161034267	6	+	26627737	HeLa	viability after 15 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.4318711052534002	[559]	[247,456,210]	3	hSpCas9	negative selection	1654354
161049724	161049747	6	-	26627737	HeLa	viability after 15 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.04808476392274452	[632]	[372,241,175]	0	hSpCas9	negative selection	1654355
161070744	161070767	6	-	26627737	HeLa	viability after 15 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	0.4659259352465422	[305]	[247,157,103]	4	hSpCas9	negative selection	1654356
161073478	161073501	6	+	26627737	HeLa	viability after 15 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.22214717988217259	[583]	[325,138,139]	-2	hSpCas9	negative selection	1654357
161086360	161086383	6	+	26627737	HeLa	viability after 15 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	-0.7054571671415264	[568]	[156,198,63]	-6	hSpCas9	negative selection	1654358
160991965	160991988	6	-	26627737	HeLa	viability after 18 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	-0.4517062788416326	[561]	[102,147,169]	-4	hSpCas9	negative selection	1736664
161034244	161034267	6	+	26627737	HeLa	viability after 18 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.4771533211622927	[559]	[176,388,210]	4	hSpCas9	negative selection	1736669
161049724	161049747	6	-	26627737	HeLa	viability after 18 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.05924156130040148	[632]	[248,206,175]	0	hSpCas9	negative selection	1736670
161070744	161070767	6	-	26627737	HeLa	viability after 18 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	0.5223027957563191	[305]	[177,132,103]	4	hSpCas9	negative selection	1736671
161073478	161073501	6	+	26627737	HeLa	viability after 18 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.17634672013416963	[583]	[225,121,139]	-1	hSpCas9	negative selection	1736672
161086360	161086383	6	+	26627737	HeLa	viability after 18 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	-0.7422812332892463	[568]	[98,163,63]	-6	hSpCas9	negative selection	1736673
160991965	160991988	6	-	26627737	HCT116	viability after 6 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.803221331684399	[681]	[315,115]	4	hSpCas9	negative selection	1818979
161034244	161034267	6	+	26627737	HCT116	viability after 6 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	-0.2653402767868108	[1283]	[107,200]	-1	hSpCas9	negative selection	1818984
161049724	161049747	6	-	26627737	HCT116	viability after 6 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	-0.8893464364866431	[1318]	[187,69]	-5	hSpCas9	negative selection	1818985
161070744	161070767	6	-	26627737	HCT116	viability after 6 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	-2.590223065620445	[239]	[13,1]	-9	hSpCas9	negative selection	1818986
161073478	161073501	6	+	26627737	HCT116	viability after 6 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	2.5610162334203674	[690]	[185,891]	9	hSpCas9	negative selection	1818987
161086360	161086383	6	+	26627737	HCT116	viability after 6 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	-0.08562724497590152	[620]	[227,16]	0	hSpCas9	negative selection	1818988
160991965	160991988	6	-	26627737	HCT116	viability after 8 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	-0.03784011773690066	[454]	[148,256,323]	0	hSpCas9	negative selection	1901294
161034244	161034267	6	+	26627737	HCT116	viability after 8 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.46368213857981805	[373]	[398,199,255]	5	hSpCas9	negative selection	1901299
161049724	161049747	6	-	26627737	HCT116	viability after 8 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.5291565827014636	[440]	[312,358,378]	5	hSpCas9	negative selection	1901300
161070744	161070767	6	-	26627737	HCT116	viability after 8 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	-0.4414098642855403	[305]	[77,112,179]	-5	hSpCas9	negative selection	1901301
161073478	161073501	6	+	26627737	HCT116	viability after 8 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.8940054370067818	[508]	[133,127,189]	-8	hSpCas9	negative selection	1901302
161086360	161086383	6	+	26627737	HCT116	viability after 8 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	0.2355962071842272	[197]	[152,119,112]	2	hSpCas9	negative selection	1901303
160991965	160991988	6	-	26627737	HCT116	viability after 9 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	-0.3417851804812157	[681]	[179,114]	-2	hSpCas9	negative selection	1983609
161034244	161034267	6	+	26627737	HCT116	viability after 9 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	-1.2272596065412225	[1283]	[146,145]	-7	hSpCas9	negative selection	1983614
161049724	161049747	6	-	26627737	HCT116	viability after 9 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	-1.3963824457624234	[1318]	[192,86]	-7	hSpCas9	negative selection	1983615
161070744	161070767	6	-	26627737	HCT116	viability after 9 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	-0.9630312150206748	[239]	[14,46]	-6	hSpCas9	negative selection	1983616
161073478	161073501	6	+	26627737	HCT116	viability after 9 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.12543818754855435	[690]	[274,142]	1	hSpCas9	negative selection	1983617
161086360	161086383	6	+	26627737	HCT116	viability after 9 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	0.8348076711620928	[620]	[340,259]	6	hSpCas9	negative selection	1983618
160991965	160991988	6	-	26627737	HCT116	viability after 12 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.3634531156912847	[454]	[310,242,366]	3	hSpCas9	negative selection	2065924
161034244	161034267	6	+	26627737	HCT116	viability after 12 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.8672054511154257	[373]	[209,373,504]	7	hSpCas9	negative selection	2065929
161049724	161049747	6	-	26627737	HCT116	viability after 12 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.2914184561737573	[440]	[336,315,193]	3	hSpCas9	negative selection	2065930
161070744	161070767	6	-	26627737	HCT116	viability after 12 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	-0.9052993115127187	[305]	[84,99,72]	-7	hSpCas9	negative selection	2065931
161073478	161073501	6	+	26627737	HCT116	viability after 12 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-1.2255581798357742	[508]	[128,77,133]	-8	hSpCas9	negative selection	2065932
161086360	161086383	6	+	26627737	HCT116	viability after 12 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	0.5451468468608308	[197]	[164,178,110]	5	hSpCas9	negative selection	2065933
160991965	160991988	6	-	26627737	HCT116	viability after 15 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.33048003426490546	[454]	[402,198,391]	3	hSpCas9	negative selection	2148239
161034244	161034267	6	+	26627737	HCT116	viability after 15 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.3217535654888128	[373]	[207,238,349]	3	hSpCas9	negative selection	2148244
161049724	161049747	6	-	26627737	HCT116	viability after 15 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.4602875862018546	[440]	[318,394,327]	4	hSpCas9	negative selection	2148245
161070744	161070767	6	-	26627737	HCT116	viability after 15 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	-1.5371578502367678	[305]	[94,42,47]	-8	hSpCas9	negative selection	2148246
161073478	161073501	6	+	26627737	HCT116	viability after 15 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-1.9027024286573009	[508]	[81,74,77]	-9	hSpCas9	negative selection	2148247
161086360	161086383	6	+	26627737	HCT116	viability after 15 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	0.7817671998054212	[197]	[208,172,205]	6	hSpCas9	negative selection	2148248
160991965	160991988	6	-	26627737	HCT116	viability after 18 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.0833815691287666	[454]	[314,140,249]	0	hSpCas9	negative selection	2230554
161034244	161034267	6	+	26627737	HCT116	viability after 18 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.1876450002234838	[373]	[179,188,251]	1	hSpCas9	negative selection	2230559
161049724	161049747	6	-	26627737	HCT116	viability after 18 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.5329489418094752	[440]	[226,319,380]	4	hSpCas9	negative selection	2230560
161070744	161070767	6	-	26627737	HCT116	viability after 18 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	-1.5984489014556722	[305]	[47,53,43]	-8	hSpCas9	negative selection	2230561
161073478	161073501	6	+	26627737	HCT116	viability after 18 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-2.2091950134816094	[508]	[51,24,85]	-9	hSpCas9	negative selection	2230562
161086360	161086383	6	+	26627737	HCT116	viability after 18 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	0.6805957897668387	[197]	[192,130,136]	5	hSpCas9	negative selection	2230563
160991934	160991957	6	+	24336569	HL60	viability	GAGAGAAGCCGCTGCCGCGCTGG	MAP3K4	ENSG00000085511	-0.4631595240411999	[498]	[765]	-4	hSpCas9	negative selection	2275918
160991942	160991965	6	-	24336569	HL60	viability	AGGAGGGACCAGCGCGGCAGCGG	MAP3K4	ENSG00000085511	1.136225920713547	[438]	[2041]	8	hSpCas9	negative selection	2275919
160991948	160991971	6	-	24336569	HL60	viability	GGCGGGAGGAGGGACCAGCGCGG	MAP3K4	ENSG00000085511	-0.30672185565973376	[293]	[502]	-3	hSpCas9	negative selection	2275920
160991958	160991981	6	-	24336569	HL60	viability	TGACGGCAAAGGCGGGAGGAGGG	MAP3K4	ENSG00000085511	0.45843185236419237	[1072]	[3119]	4	hSpCas9	negative selection	2275921
160991965	160991988	6	-	24336569	HL60	viability	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.09917933823462644	[2979]	[6754]	1	hSpCas9	negative selection	2275922
160991975	160991998	6	-	24336569	HL60	viability	CATGGCGGCGGCAGGCGTGACGG	MAP3K4	ENSG00000085511	0.7913186406593582	[855]	[3134]	6	hSpCas9	negative selection	2275923
160991987	160992010	6	-	24336569	HL60	viability	CGGCGGCTCCTCCATGGCGGCGG	MAP3K4	ENSG00000085511	-0.7425089941808813	[1094]	[1384]	-6	hSpCas9	negative selection	2275924
160991993	160992016	6	-	24336569	HL60	viability	CGGTGGCGGCGGCTCCTCCATGG	MAP3K4	ENSG00000085511	7.3321638283952755	[0]	[340]	9	hSpCas9	negative selection	2275925
160992022	160992045	6	-	24336569	HL60	viability	GGTTCCGGTGGCGGTGGTGGCGG	MAP3K4	ENSG00000085511	-2.05100494587838	[702]	[358]	-9	hSpCas9	negative selection	2275926
160992028	160992051	6	-	24336569	HL60	viability	GTCTCGGGTTCCGGTGGCGGTGG	MAP3K4	ENSG00000085511	0.27556779521438185	[405]	[1039]	2	hSpCas9	negative selection	2275927
160991934	160991957	6	+	24336569	KBM7	viability	GAGAGAAGCCGCTGCCGCGCTGG	MAP3K4	ENSG00000085511	0.5208381582412377	[380]	[1490]	5	hSpCas9	negative selection	2343095
160991942	160991965	6	-	24336569	KBM7	viability	AGGAGGGACCAGCGCGGCAGCGG	MAP3K4	ENSG00000085511	0.6599191893633989	[529]	[2283]	6	hSpCas9	negative selection	2343096
160991948	160991971	6	-	24336569	KBM7	viability	GGCGGGAGGAGGGACCAGCGCGG	MAP3K4	ENSG00000085511	-0.33525049644600635	[246]	[533]	-3	hSpCas9	negative selection	2343097
160991958	160991981	6	-	24336569	KBM7	viability	TGACGGCAAAGGCGGGAGGAGGG	MAP3K4	ENSG00000085511	0.7587017421656659	[848]	[3917]	6	hSpCas9	negative selection	2343098
160991965	160991988	6	-	24336569	KBM7	viability	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.3334874915937851	[1700]	[5845]	3	hSpCas9	negative selection	2343099
160991975	160991998	6	-	24336569	KBM7	viability	CATGGCGGCGGCAGGCGTGACGG	MAP3K4	ENSG00000085511	-0.3833887781279759	[1043]	[2182]	-3	hSpCas9	negative selection	2343100
160991987	160992010	6	-	24336569	KBM7	viability	CGGCGGCTCCTCCATGGCGGCGG	MAP3K4	ENSG00000085511	0.5569221956860582	[799]	[3209]	5	hSpCas9	negative selection	2343101
160991993	160992016	6	-	24336569	KBM7	viability	CGGTGGCGGCGGCTCCTCCATGG	MAP3K4	ENSG00000085511	-1.9391912209353297	[186]	[132]	-8	hSpCas9	negative selection	2343102
160992022	160992045	6	-	24336569	KBM7	viability	GGTTCCGGTGGCGGTGGTGGCGG	MAP3K4	ENSG00000085511	-1.6367520825844735	[414]	[363]	-8	hSpCas9	negative selection	2343103
160992028	160992051	6	-	24336569	KBM7	viability	GTCTCGGGTTCCGGTGGCGGTGG	MAP3K4	ENSG00000085511	1.1759603362829694	[245]	[1515]	8	hSpCas9	negative selection	2343104
160992054	160992077	6	+	27013184	SW480	treatment with recombinant TRAIL	GTCAGAACCCGAGTGCTGCTTGG	MAP3K4	ENSG00000085511	0.40737934485624727	[377,285]	[167,226]	2	hSpCas9	positive selection	2955529
161034237	161034260	6	+	27013184	SW480	treatment with recombinant TRAIL	CCCTGCACACTGTCTTTCATAGG	MAP3K4	ENSG00000085511	0.37949892379857353	[600,1111]	[432,517]	2	hSpCas9	positive selection	2955530
160992057	160992080	6	+	27013184	SW480	treatment with recombinant TRAIL	AGAACCCGAGTGCTGCTTGGCGG	MAP3K4	ENSG00000085511	2.4875318676164673	[98,72]	[167,271]	9	hSpCas9	positive selection	2955531
161034244	161034267	6	+	27013184	SW480	treatment with recombinant TRAIL	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	-0.8064686106423195	[161,207]	[7,97]	-4	hSpCas9	positive selection	2955532
161070682	161070705	6	+	27013184	SW480	treatment with recombinant TRAIL	GAAATGCAGTGCTGTGTCGTGGG	MAP3K4	ENSG00000085511	3.1538520898490883	[67,230]	[240,980]	9	hSpCas9	positive selection	2955533
161070685	161070708	6	+	27013184	SW480	treatment with recombinant TRAIL	ATGCAGTGCTGTGTCGTGGGAGG	MAP3K4	ENSG00000085511	-0.7981155432443989	[889,1108]	[250,237]	-4	hSpCas9	positive selection	2955534
161101958	161101981	6	+	27013184	SW480	treatment with recombinant TRAIL	GAGTCGTCACTCAAGCCCCACGG	MAP3K4	ENSG00000085511	-1.903859167996612	[52,68]	[1,13]	-7	hSpCas9	positive selection	2955535
161101961	161101984	6	+	27013184	SW480	treatment with recombinant TRAIL	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	0.5574922314845017	[14,57]	[35,1]	2	hSpCas9	positive selection	2955536
161101927	161101950	6	-	27013184	SW480	treatment with recombinant TRAIL	AAACTGCAATTCAGCAGCTATGG	MAP3K4	ENSG00000085511	1.1429141169828987	[112,135]	[82,166]	5	hSpCas9	positive selection	2955537
161101955	161101978	6	-	27013184	SW480	treatment with recombinant TRAIL	TGGGGCTTGAGTGACGACTCAGG	MAP3K4	ENSG00000085511	-1.3389182688619146	[360,599]	[113,31]	-6	hSpCas9	positive selection	2955538
161034245	161034268	6	+	27013184	SW480	treatment with recombinant TRAIL	ACTGTCTTTCATAGGCAAGAGGG	MAP3K4	ENSG00000085511	-0.9322747831360604	[641,394]	[108,134]	-4	hSpCas9	positive selection	2955539
161034253	161034276	6	+	27013184	SW480	treatment with recombinant TRAIL	TCATAGGCAAGAGGGCACATTGG	MAP3K4	ENSG00000085511	1.065277458338644	[33,73]	[54,35]	5	hSpCas9	positive selection	2955540
161034254	161034277	6	+	27013184	SW480	treatment with recombinant TRAIL	CATAGGCAAGAGGGCACATTGGG	MAP3K4	ENSG00000085511	-5.379826030930001	[84,321]	[1,1]	-9	hSpCas9	positive selection	2955541
161070665	161070688	6	-	27013184	SW480	treatment with recombinant TRAIL	CATTTCTCCTCAGATGAAGGTGG	MAP3K4	ENSG00000085511	0.195288295894666	[125,136]	[27,116]	1	hSpCas9	positive selection	2955542
161070668	161070691	6	-	27013184	SW480	treatment with recombinant TRAIL	CTGCATTTCTCCTCAGATGAAGG	MAP3K4	ENSG00000085511	-1.5156999595770357	[270,229]	[54,13]	-6	hSpCas9	positive selection	2955544
161034329	161034352	6	+	27013184	SW480	treatment with recombinant TRAIL	ACAAATACAGAGAATCTTTATGG	MAP3K4	ENSG00000085511	0.8508336322188217	[251,372]	[224,258]	4	hSpCas9	positive selection	2955545
161034387	161034410	6	+	27013184	SW480	treatment with recombinant TRAIL	GCATGTCAACCAAACATCAGAGG	MAP3K4	ENSG00000085511	0.09814235113136083	[125,204]	[47,112]	0	hSpCas9	positive selection	2955546
161034237	161034260	6	-	27013184	SW480	treatment with recombinant TRAIL	CCTATGAAAGACAGTGTGCAGGG	MAP3K4	ENSG00000085511	1.2124738110114626	[1,1]	[1,1]	6	hSpCas9	positive selection	2955547
161034238	161034261	6	-	27013184	SW480	treatment with recombinant TRAIL	GCCTATGAAAGACAGTGTGCAGG	MAP3K4	ENSG00000085511	0.7092700630347628	[68,88]	[57,50]	3	hSpCas9	positive selection	2955548
161034296	161034319	6	-	27013184	SW480	treatment with recombinant TRAIL	AAGTCTTCTAGATCAGATTCAGG	MAP3K4	ENSG00000085511	-0.21998735418664553	[145,306]	[91,65]	-1	hSpCas9	positive selection	2955549
161034371	161034394	6	-	27013184	SW480	treatment with recombinant TRAIL	GACATGCGTTTCATCTGTCGAGG	MAP3K4	ENSG00000085511	1.36734929097985	[111,148]	[173,99]	6	hSpCas9	positive selection	2955550
161034396	161034419	6	-	27013184	SW480	treatment with recombinant TRAIL	CACATTATTCCTCTGATGTTTGG	MAP3K4	ENSG00000085511	-1.2562018137395383	[16,8]	[1,2]	-5	hSpCas9	positive selection	2955551
161034397	161034420	6	+	27013184	SW480	treatment with recombinant TRAIL	CAAACATCAGAGGAATAATGTGG	MAP3K4	ENSG00000085511	2.719028229395357	[8,35]	[62,56]	9	hSpCas9	positive selection	2955552
161070639	161070662	6	+	27013184	SW480	treatment with recombinant TRAIL	CAGATTATGTGCAGTTGTCAAGG	MAP3K4	ENSG00000085511	-1.0589215488195198	[406,333]	[76,77]	-5	hSpCas9	positive selection	2955553
161034425	161034448	6	-	27013184	SW480	treatment with recombinant TRAIL	TTCAAATTAGACCGACTGGCTGG	MAP3K4	ENSG00000085511	1.3050811723618088	[81,100]	[113,71]	6	hSpCas9	positive selection	2955554
161034429	161034452	6	-	27013184	SW480	treatment with recombinant TRAIL	ACCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	1.0342839037652256	[12,7]	[6,12]	5	hSpCas9	positive selection	2955555
161034414	161034437	6	+	27013184	SW480	treatment with recombinant TRAIL	ATGTGGGGAGGCCAGCCAGTCGG	MAP3K4	ENSG00000085511	0.9524093393293458	[344,530]	[395,305]	4	hSpCas9	positive selection	2955556
161070658	161070681	6	+	27013184	SW480	treatment with recombinant TRAIL	AAGGACACCACCTTCATCTGAGG	MAP3K4	ENSG00000085511	2.7850285518804356	[37,84]	[224,107]	9	hSpCas9	positive selection	2955557
161034428	161034451	6	+	27013184	SW480	treatment with recombinant TRAIL	GCCAGTCGGTCTAATTTGAAAGG	MAP3K4	ENSG00000085511	0.9665968221075842	[284,301]	[68,499]	4	hSpCas9	positive selection	2955558
161070681	161070704	6	+	27013184	SW480	treatment with recombinant TRAIL	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.767709006569828	[475,743]	[197,782]	4	hSpCas9	positive selection	2955559
161048984	161049007	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTCTCAAAGAAAAAAGACAGGG	MAP3K4	ENSG00000085511	-0.2866811438322735	[2,2]	[2,0]	-4	hSpCas9	positive selection	3001159
161049935	161049958	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAAGGGCACGTATAGCATTGG	MAP3K4	ENSG00000085511	0.06954427409487714	[3,3]	[4,1]	1	hSpCas9	positive selection	3001160
161049296	161049319	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGCATCTCCAACGCCAGAGGG	MAP3K4	ENSG00000085511	-0.043404713911911266	[4,3]	[4,2]	0	hSpCas9	positive selection	3001161
161049223	161049246	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAATGGTACTTCAGTAGAAGGG	MAP3K4	ENSG00000085511	0.0874341908272866	[4,3]	[4,2]	1	hSpCas9	positive selection	3001162
161048984	161049007	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTCTCAAAGAAAAAAGACAGGG	MAP3K4	ENSG00000085511	0.299748353808299	[2,2]	[2,1]	5	hSpCas9	positive selection	3069017
161049935	161049958	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAAGGGCACGTATAGCATTGG	MAP3K4	ENSG00000085511	0.7236903570723356	[3,3]	[3,4]	9	hSpCas9	positive selection	3069018
161049296	161049319	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGCATCTCCAACGCCAGAGGG	MAP3K4	ENSG00000085511	0.00813948517652821	[4,4]	[2,2]	0	hSpCas9	positive selection	3069019
161049223	161049246	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAATGGTACTTCAGTAGAAGGG	MAP3K4	ENSG00000085511	0.10846398284972095	[4,4]	[3,2]	2	hSpCas9	positive selection	3069020
161084605	161084628		-	24336571	A375	resistance to PLX after 7 days	CAACTCCAACCTGATTTCGTCGG	MAP3K4	ENSG00000085511	0.2692413465826087	[20,21]	[26,25]	7	hSpCas9	positive selection	3126295
161084596	161084619		+	24336571	A375	resistance to PLX after 7 days	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	-0.263465480460197	[34,39]	[30,30]	-7	hSpCas9	positive selection	3126296
161070717	161070740		-	24336571	A375	resistance to PLX after 7 days	TTCGAATGAAGGTAAATCCATGG	MAP3K4	ENSG00000085511	0.28240752306835537	[20,25]	[34,22]	7	hSpCas9	positive selection	3126297
161084605	161084628		-	24336571	A375	resistance to PLX after 14 days	CAACTCCAACCTGATTTCGTCGG	MAP3K4	ENSG00000085511	0.23963320126873267	[26,23]	[13,13]	2	hSpCas9	positive selection	3184088
161084596	161084619		+	24336571	A375	resistance to PLX after 14 days	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.22908853307458754	[29,31]	[15,16]	2	hSpCas9	positive selection	3184089
161070717	161070740		-	24336571	A375	resistance to PLX after 14 days	TTCGAATGAAGGTAAATCCATGG	MAP3K4	ENSG00000085511	2.8774635484077344	[26,24]	[69,110]	9	hSpCas9	positive selection	3184090
161084605	161084628		-	24336571	A375	viability after 7 days	CAACTCCAACCTGATTTCGTCGG	MAP3K4	ENSG00000085511	-0.6876971372617837	[37]	[20,21]	-7	hSpCas9	negative selection	3241881
161084596	161084619		+	24336571	A375	viability after 7 days	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.4416858371355983	[28]	[34,39]	6	hSpCas9	negative selection	3241882
161070717	161070740		-	24336571	A375	viability after 7 days	TTCGAATGAAGGTAAATCCATGG	MAP3K4	ENSG00000085511	0.41526442310707556	[18]	[20,25]	6	hSpCas9	negative selection	3241883
161084605	161084628		-	24336571	A375	viability after 14 days	CAACTCCAACCTGATTTCGTCGG	MAP3K4	ENSG00000085511	-0.4428465554027027	[37]	[26,23]	-5	hSpCas9	negative selection	3299674
161084596	161084619		+	24336571	A375	viability after 14 days	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.19406337398307216	[28]	[29,31]	2	hSpCas9	negative selection	3299675
161070717	161070740		-	24336571	A375	viability after 14 days	TTCGAATGAAGGTAAATCCATGG	MAP3K4	ENSG00000085511	0.5632311489531198	[18]	[26,24]	7	hSpCas9	negative selection	3299676
161086391	161086414	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.22390320990838475	[130,130]	[0,0]	1	hSpCas9	positive selection	3378417
161070829	161070852	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	2.8650087886670743	[62,62]	[2,2]	8	hSpCas9	positive selection	3378418
161086444	161086467	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	-0.6910410201388426	[246,246]	[0,0]	-5	hSpCas9	positive selection	3378419
161048983	161049006	6	+	26780180	HT29	viability (Avana library 4 designs)	AGTCTCAAAGAAAAAAGACAGGG	MAP3K4	ENSG00000085511	1.46954290635054	[]	[]	6	hSpCas9	negative selection	3438803
161049934	161049957	6	+	26780180	HT29	viability (Avana library 4 designs)	GCAAAGGGCACGTATAGCATTGG	MAP3K4	ENSG00000085511	1.29343631015496	[]	[]	5	hSpCas9	negative selection	3438804
161049295	161049318	6	+	26780180	HT29	viability (Avana library 4 designs)	TGAGCATCTCCAACGCCAGAGGG	MAP3K4	ENSG00000085511	0.272733525942303	[]	[]	1	hSpCas9	negative selection	3438805
161049222	161049245	6	+	26780180	HT29	viability (Avana library 4 designs)	TTAATGGTACTTCAGTAGAAGGG	MAP3K4	ENSG00000085511	1.73999638019503	[]	[]	6	hSpCas9	negative selection	3438806
161049295	161049318	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGCATCTCCAACGCCAGAGGG	MAP3K4	ENSG00000085511	-1.8864800001818	[]	[]	-2	hSpCas9	negative selection	3528234
161049222	161049245	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTAATGGTACTTCAGTAGAAGGG	MAP3K4	ENSG00000085511	-10.2168237457711	[]	[]	-7	hSpCas9	negative selection	3528235
161048983	161049006	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTCTCAAAGAAAAAAGACAGGG	MAP3K4	ENSG00000085511	-12.3740020384518	[]	[]	-8	hSpCas9	negative selection	3528236
161049934	161049957	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAAGGGCACGTATAGCATTGG	MAP3K4	ENSG00000085511	5.32060754601147	[]	[]	8	hSpCas9	negative selection	3528237
160991987	160992010	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGGCGGCTCCTCCATGGCGGCGG	MAP3K4	ENSG00000085511	2.63276729297338	[]	[]	4	hSpCas9	negative selection	3528238
161034414	161034437	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGTGGGGAGGCCAGCCAGTCGG	MAP3K4	ENSG00000085511	5.13979410522723	[]	[]	8	hSpCas9	negative selection	3528239
161049295	161049318	6	+	26780180	A375	viability (Avana lentiGuide)	TGAGCATCTCCAACGCCAGAGGG	MAP3K4	ENSG00000085511	-2.6154880823727	[]	[]	-4	hSpCas9	negative selection	3636893
161049222	161049245	6	+	26780180	A375	viability (Avana lentiGuide)	TTAATGGTACTTCAGTAGAAGGG	MAP3K4	ENSG00000085511	-3.55159897311165	[]	[]	-6	hSpCas9	negative selection	3636894
161048983	161049006	6	+	26780180	A375	viability (Avana lentiGuide)	AGTCTCAAAGAAAAAAGACAGGG	MAP3K4	ENSG00000085511	13.5595919609598	[]	[]	7	hSpCas9	negative selection	3636895
161049934	161049957	6	+	26780180	A375	viability (Avana lentiGuide)	GCAAAGGGCACGTATAGCATTGG	MAP3K4	ENSG00000085511	5.68412775045959	[]	[]	5	hSpCas9	negative selection	3636896
160991987	160992010	6	-	26780180	A375	viability (Avana lentiGuide)	CGGCGGCTCCTCCATGGCGGCGG	MAP3K4	ENSG00000085511	3.4153574550743	[]	[]	3	hSpCas9	negative selection	3636897
161034414	161034437	6	+	26780180	A375	viability (Avana lentiGuide)	ATGTGGGGAGGCCAGCCAGTCGG	MAP3K4	ENSG00000085511	8.49545494278869	[]	[]	6	hSpCas9	negative selection	3636898
161049295	161049318	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGCATCTCCAACGCCAGAGGG	MAP3K4	ENSG00000085511	-0.12326305484717358	[4]	[4,4]	-2	hSpCas9	positive selection	3745552
161049222	161049245	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAATGGTACTTCAGTAGAAGGG	MAP3K4	ENSG00000085511	-0.5149994429019414	[9]	[6,5]	-6	hSpCas9	positive selection	3745553
161048983	161049006	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTCTCAAAGAAAAAAGACAGGG	MAP3K4	ENSG00000085511	-1.411693123894944	[6]	[2,0]	-9	hSpCas9	positive selection	3745554
161049934	161049957	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAAGGGCACGTATAGCATTGG	MAP3K4	ENSG00000085511	0.41114350276104566	[4]	[5,7]	9	hSpCas9	positive selection	3745555
160991987	160992010	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGCGGCTCCTCCATGGCGGCGG	MAP3K4	ENSG00000085511	0.38729723280954104	[4]	[6,5]	9	hSpCas9	positive selection	3745556
161034414	161034437	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGTGGGGAGGCCAGCCAGTCGG	MAP3K4	ENSG00000085511	0.2337918386319296	[4]	[5,4]	6	hSpCas9	positive selection	3745557
161049295	161049318	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGCATCTCCAACGCCAGAGGG	MAP3K4	ENSG00000085511	0.05428993903922844	[5]	[4,5]	1	hSpCas9	positive selection	3854159
161049222	161049245	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAATGGTACTTCAGTAGAAGGG	MAP3K4	ENSG00000085511	0.04462848196539995	[5]	[6,3]	0	hSpCas9	positive selection	3854160
161048983	161049006	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTCTCAAAGAAAAAAGACAGGG	MAP3K4	ENSG00000085511	-0.8488076264261712	[3]	[0,2]	-8	hSpCas9	positive selection	3854161
161049934	161049957	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAAGGGCACGTATAGCATTGG	MAP3K4	ENSG00000085511	0.14237078377245127	[5]	[4,5]	3	hSpCas9	positive selection	3854162
160991987	160992010	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGCGGCTCCTCCATGGCGGCGG	MAP3K4	ENSG00000085511	-0.02228409498392865	[6]	[4,5]	0	hSpCas9	positive selection	3854163
161034414	161034437	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGTGGGGAGGCCAGCCAGTCGG	MAP3K4	ENSG00000085511	-0.29218613905122515	[5]	[4,2]	-4	hSpCas9	positive selection	3854164
161070681	161070704	6	+	26780180	A375	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.924632834982266	[]	[]	4	hSpCas9	negative selection	3959679
161086391	161086414	6	+	26780180	A375	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.878630547666235	[]	[]	3	hSpCas9	negative selection	3959680
161070829	161070852	6	+	26780180	A375	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	1.14972551180591	[]	[]	6	hSpCas9	negative selection	3959681
161084596	161084619	6	+	26780180	A375	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	1.27331513419222	[]	[]	7	hSpCas9	negative selection	3959682
161084490	161084513	6	+	26780180	A375	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	1.30624866116517	[]	[]	7	hSpCas9	negative selection	3959683
161086444	161086467	6	-	26780180	A375	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.6734291047179	[]	[]	2	hSpCas9	negative selection	3959684
161070681	161070704	6	+	26780180	HT29	viability (GeCKOv2 library)	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.660050869361408	[]	[]	2	hSpCas9	negative selection	4067645
161086391	161086414	6	+	26780180	HT29	viability (GeCKOv2 library)	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.839068950972489	[]	[]	3	hSpCas9	negative selection	4067646
161070829	161070852	6	+	26780180	HT29	viability (GeCKOv2 library)	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	1.62996956406866	[]	[]	8	hSpCas9	negative selection	4067647
161084596	161084619	6	+	26780180	HT29	viability (GeCKOv2 library)	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	1.26589896289788	[]	[]	6	hSpCas9	negative selection	4067648
161084490	161084513	6	+	26780180	HT29	viability (GeCKOv2 library)	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	1.74134632196965	[]	[]	8	hSpCas9	negative selection	4067649
161086444	161086467	6	-	26780180	HT29	viability (GeCKOv2 library)	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.293707377384343	[]	[]	0	hSpCas9	negative selection	4067650
161084605	161084628	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAACTCCAACCTGATTTCGTCGG	MAP3K4	ENSG00000085511	0.235510848728009	[4]	[2,3]	6	hSpCas9	positive selection	4150512
161084596	161084619	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.47854671290426976	[5]	[5,4]	9	hSpCas9	positive selection	4150513
161070717	161070740	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCGAATGAAGGTAAATCCATGG	MAP3K4	ENSG00000085511	0.6019900623488913	[4]	[2,6]	9	hSpCas9	positive selection	4150514
161084605	161084628	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAACTCCAACCTGATTTCGTCGG	MAP3K4	ENSG00000085511	1.1347793525908654	[4]	[6,4,3,4]	8	hSpCas9	positive selection	4214534
161084596	161084619	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.880038365974652	[4]	[4,2,1,3]	6	hSpCas9	positive selection	4214535
161070717	161070740	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCGAATGAAGGTAAATCCATGG	MAP3K4	ENSG00000085511	0.9586318062360163	[4]	[4,2,5,3]	6	hSpCas9	positive selection	4214536
161084596	161084619	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	-0.21082861203659753	[2]	[2,0]	-4	hSpCas9	positive selection	4281846
161084490	161084513	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.2477285925943739	[3]	[3,1]	-5	hSpCas9	positive selection	4281847
161070681	161070704	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.19551955632738355	[2]	[2,1]	-4	hSpCas9	positive selection	4281848
161086391	161086414	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.5051607187717364	[2]	[1,3]	9	hSpCas9	positive selection	4346104
161070829	161070852	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.5624312135791419	[2]	[1,0]	-8	hSpCas9	positive selection	4346105
161086444	161086467	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.7155982085236318	[3]	[3,4]	9	hSpCas9	positive selection	4346106
161034429	161034451	6	-	27760321	OCIAML3	viability	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	0.24930692662357862	[342,282]	[306,266]	3	hSpCas9	negative selection	4416614
161049092	161049114	6	+	27760321	OCIAML3	viability	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	-0.2128833695188752	[330,281]	[160,264]	-2	hSpCas9	negative selection	4416615
161049724	161049746	6	-	27760321	OCIAML3	viability	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.1841491225514657	[552,509]	[440,512]	2	hSpCas9	negative selection	4416616
161049959	161049981	6	+	27760321	OCIAML3	viability	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	0.38454794839623196	[549,509]	[568,504]	4	hSpCas9	negative selection	4416617
161080990	161081012	6	+	27760321	OCIAML3	viability	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.06179723582669028	[216,124]	[113,140]	0	hSpCas9	negative selection	4416618
161034429	161034451	6	-	27760321	OCIAML2	viability	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	-0.6353599471268145	[342,282]	[144,184]	-6	hSpCas9	negative selection	4500077
161049092	161049114	6	+	27760321	OCIAML2	viability	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	0.1851461786674387	[330,281]	[242,330]	2	hSpCas9	negative selection	4500078
161049724	161049746	6	-	27760321	OCIAML2	viability	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.049064412220007125	[552,509]	[345,574]	0	hSpCas9	negative selection	4500079
161049959	161049981	6	+	27760321	OCIAML2	viability	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	0.6573603006099241	[549,509]	[583,797]	8	hSpCas9	negative selection	4500080
161080990	161081012	6	+	27760321	OCIAML2	viability	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.46338907134713625	[216,124]	[116,73]	-5	hSpCas9	negative selection	4500081
161034429	161034451	6	-	27760321	MV411	viability	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	-0.013775296616377386	[342,282]	[261,115]	0	hSpCas9	negative selection	4583540
161049092	161049114	6	+	27760321	MV411	viability	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	-0.451836305501777	[330,281]	[134,165]	-3	hSpCas9	negative selection	4583541
161049724	161049746	6	-	27760321	MV411	viability	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.6913172477481186	[552,509]	[728,321]	5	hSpCas9	negative selection	4583542
161049959	161049981	6	+	27760321	MV411	viability	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	-0.9514524322677996	[549,509]	[50,375]	-6	hSpCas9	negative selection	4583543
161080990	161081012	6	+	27760321	MV411	viability	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.11774821213879494	[216,124]	[44,232]	0	hSpCas9	negative selection	4583544
161034429	161034451	6	-	27760321	HL60	viability	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	0.8087625775759064	[342,282]	[406,486]	8	hSpCas9	negative selection	4667003
161049092	161049114	6	+	27760321	HL60	viability	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	-0.1696802551170712	[330,281]	[150,296]	-2	hSpCas9	negative selection	4667004
161049724	161049746	6	-	27760321	HL60	viability	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	-0.08243745430156485	[552,509]	[311,513]	-1	hSpCas9	negative selection	4667005
161049959	161049981	6	+	27760321	HL60	viability	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	0.8407245355502436	[549,509]	[560,1002]	8	hSpCas9	negative selection	4667006
161080990	161081012	6	+	27760321	HL60	viability	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.20316454963866737	[216,124]	[216,94]	2	hSpCas9	negative selection	4667007
161034429	161034451	6	-	27760321	HT1080	viability	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	1.2205704901276109	[282,220]	[232,234]	6	hSpCas9	negative selection	4750466
161049092	161049114	6	+	27760321	HT1080	viability	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	2.1525138924789724	[281,219]	[550,327]	9	hSpCas9	negative selection	4750467
161049724	161049746	6	-	27760321	HT1080	viability	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	1.0659241712500886	[509,397]	[275,490]	6	hSpCas9	negative selection	4750468
161049959	161049981	6	+	27760321	HT1080	viability	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	2.420072461172003	[509,397]	[1240,668]	9	hSpCas9	negative selection	4750469
161080990	161081012	6	+	27760321	HT1080	viability	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.7469970557682024	[124,97]	[75,72]	4	hSpCas9	negative selection	4750470
161034429	161034451	6	-	27760321	HT29	viability after 7 days	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	-0.08154603000808569	[282,220]	[374,310,243]	-1	hSpCas9	negative selection	4833929
161049092	161049114	6	+	27760321	HT29	viability after 7 days	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	-0.31680333434910946	[281,219]	[279,149,346]	-4	hSpCas9	negative selection	4833930
161049724	161049746	6	-	27760321	HT29	viability after 7 days	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	-0.6432827584991835	[509,397]	[377,361,380]	-7	hSpCas9	negative selection	4833931
161049959	161049981	6	+	27760321	HT29	viability after 7 days	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	0.5208325848716526	[509,397]	[764,804,927]	7	hSpCas9	negative selection	4833932
161080990	161081012	6	+	27760321	HT29	viability after 7 days	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.4126486431065204	[124,97]	[104,57,157]	-6	hSpCas9	negative selection	4833933
161034429	161034451	6	-	27760321	HT29	viability after 25 days	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	-0.08626602967751884	[282,220]	[250,358,196]	-1	hSpCas9	negative selection	4917392
161049092	161049114	6	+	27760321	HT29	viability after 25 days	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	0.020047819914312037	[281,219]	[380,275,199]	0	hSpCas9	negative selection	4917393
161049724	161049746	6	-	27760321	HT29	viability after 25 days	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	-0.28692956840445144	[509,397]	[557,341,359]	-3	hSpCas9	negative selection	4917394
161049959	161049981	6	+	27760321	HT29	viability after 25 days	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	0.4368644967477469	[509,397]	[963,538,572]	5	hSpCas9	negative selection	4917395
161080990	161081012	6	+	27760321	HT29	viability after 25 days	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.47564042664814377	[124,97]	[154,250,120]	5	hSpCas9	negative selection	4917396
161034429	161034451	6	-	27760321	HT29	viability after 22 days	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	-0.35116702770787167	[282,220]	[272,282,126]	-3	hSpCas9	negative selection	5000855
161049092	161049114	6	+	27760321	HT29	viability after 22 days	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	0.6928690846437722	[281,219]	[734,396,265]	7	hSpCas9	negative selection	5000856
161049724	161049746	6	-	27760321	HT29	viability after 22 days	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	-0.35167978932503985	[509,397]	[479,344,406]	-3	hSpCas9	negative selection	5000857
161049959	161049981	6	+	27760321	HT29	viability after 22 days	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	0.2735565379190115	[509,397]	[584,640,678]	3	hSpCas9	negative selection	5000858
161080990	161081012	6	+	27760321	HT29	viability after 22 days	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.5944920109937577	[124,97]	[93,69,91]	-5	hSpCas9	negative selection	5000859
161034429	161034451	6	-	27760321	HT29	viability after 19 days	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	0.17563541180701503	[282,220]	[338,345,293]	1	hSpCas9	negative selection	5084318
161049092	161049114	6	+	27760321	HT29	viability after 19 days	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	0.714176344679529	[281,219]	[541,221,648]	7	hSpCas9	negative selection	5084319
161049724	161049746	6	-	27760321	HT29	viability after 19 days	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	-0.3630951832588153	[509,397]	[464,395,357]	-3	hSpCas9	negative selection	5084320
161049959	161049981	6	+	27760321	HT29	viability after 19 days	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	0.20576288930471504	[509,397]	[813,550,458]	2	hSpCas9	negative selection	5084321
161080990	161081012	6	+	27760321	HT29	viability after 19 days	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.053428780159510136	[124,97]	[78,248,65]	0	hSpCas9	negative selection	5084322
161034429	161034451	6	-	27760321	HT29	viability after 16 days	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	0.4764642764386159	[282,220]	[343,400,426]	5	hSpCas9	negative selection	5167781
161049092	161049114	6	+	27760321	HT29	viability after 16 days	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	0.43294439930510137	[281,219]	[364,527,238]	5	hSpCas9	negative selection	5167782
161049724	161049746	6	-	27760321	HT29	viability after 16 days	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	-0.17086767727525135	[509,397]	[502,390,465]	-2	hSpCas9	negative selection	5167783
161049959	161049981	6	+	27760321	HT29	viability after 16 days	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	0.5037236072196434	[509,397]	[820,756,590]	6	hSpCas9	negative selection	5167784
161080990	161081012	6	+	27760321	HT29	viability after 16 days	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.5476608944761694	[124,97]	[135,211,193]	6	hSpCas9	negative selection	5167785
161034429	161034451	6	-	27760321	HT29	viability after 13 days	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	0.07622668949277056	[282,220]	[406,253,265]	0	hSpCas9	negative selection	5251244
161049092	161049114	6	+	27760321	HT29	viability after 13 days	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	0.530461758310299	[281,219]	[445,401,413]	6	hSpCas9	negative selection	5251245
161049724	161049746	6	-	27760321	HT29	viability after 13 days	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	-0.17083433324610867	[509,397]	[522,456,425]	-2	hSpCas9	negative selection	5251246
161049959	161049981	6	+	27760321	HT29	viability after 13 days	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	0.5964701075739482	[509,397]	[906,1014,485]	7	hSpCas9	negative selection	5251247
161080990	161081012	6	+	27760321	HT29	viability after 13 days	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.04466991487289462	[124,97]	[109,98,187]	0	hSpCas9	negative selection	5251248
161034429	161034451	6	-	27760321	HT29	viability after 10 days	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	-0.013272292944272679	[282,220]	[386,192,350]	0	hSpCas9	negative selection	5334707
161049092	161049114	6	+	27760321	HT29	viability after 10 days	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	-0.25652345782891217	[281,219]	[184,317,284]	-3	hSpCas9	negative selection	5334708
161049724	161049746	6	-	27760321	HT29	viability after 10 days	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	-0.35227134144361405	[509,397]	[488,282,552]	-4	hSpCas9	negative selection	5334709
161049959	161049981	6	+	27760321	HT29	viability after 10 days	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	0.3277875847416211	[509,397]	[712,706,713]	4	hSpCas9	negative selection	5334710
161080990	161081012	6	+	27760321	HT29	viability after 10 days	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.6875370070202349	[124,97]	[121,62,73]	-7	hSpCas9	negative selection	5334711
161034429	161034451	6	-	27760321	MOLM13	viability	CCTTTCAAATTAGACCGACTGG	MAP3K4	ENSG00000085511	1.1152541210381093	[342,282]	[564,223]	7	hSpCas9	negative selection	5418170
161049092	161049114	6	+	27760321	MOLM13	viability	GGACGGACAATTAACGACCAGG	MAP3K4	ENSG00000085511	-0.13409736242823056	[330,281]	[88,214]	-1	hSpCas9	negative selection	5418171
161049724	161049746	6	-	27760321	MOLM13	viability	GGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	-0.41069176260952667	[552,509]	[385,88]	-3	hSpCas9	negative selection	5418172
161049959	161049981	6	+	27760321	MOLM13	viability	AAGAACGATCGTCCAGTGGAGG	MAP3K4	ENSG00000085511	0.8858365585967137	[549,509]	[321,748]	6	hSpCas9	negative selection	5418173
161080990	161081012	6	+	27760321	MOLM13	viability	TAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-1.0967084227807493	[216,124]	[33,52]	-6	hSpCas9	negative selection	5418174
161084596	161084619	6	+	27260156	BXPC3	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.10001521213786924	[338]	[373,363,349,436]	2	hSpCas9	negative selection	5554306
161084490	161084513	6	+	27260156	BXPC3	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.14781450800235352	[864]	[712,809,796,969]	-3	hSpCas9	negative selection	5554307
161070681	161070704	6	+	27260156	BXPC3	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.15868674064343405	[405]	[284,480,349,409]	-4	hSpCas9	negative selection	5554308
161086391	161086414	6	+	27260156	BXPC3	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.04537435152991687	[326]	[265,380,302,382]	-1	hSpCas9	negative selection	5618564
161070829	161070852	6	+	27260156	BXPC3	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.10072856068081948	[284]	[268,244,224,385]	-2	hSpCas9	negative selection	5618565
161086444	161086467	6	-	27260156	BXPC3	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.18449699620648025	[562]	[654,640,709,668]	4	hSpCas9	negative selection	5618566
161084596	161084619	6	+	27260156	A673	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.42295471392607675	[338]	[562,515,521,585]	8	hSpCas9	negative selection	5675557
161084490	161084513	6	+	27260156	A673	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.24380743548636918	[864]	[939,667,946,968]	-6	hSpCas9	negative selection	5675558
161070681	161070704	6	+	27260156	A673	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.00321755838196211	[405]	[640,391,450,480]	0	hSpCas9	negative selection	5675559
161086391	161086414	6	+	27260156	A673	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.23667478419081955	[326]	[304,308,340,376]	-5	hSpCas9	negative selection	5739815
161070829	161070852	6	+	27260156	A673	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.18502199135564734	[284]	[333,298,281,291]	-4	hSpCas9	negative selection	5739816
161086444	161086467	6	-	27260156	A673	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	-0.050829551997940536	[562]	[705,614,647,646]	-1	hSpCas9	negative selection	5739817
161084596	161084619	6	+	27260156	A375	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.8471611988932441	[338]	[706,858,793,528]	9	hSpCas9	negative selection	5796808
161084490	161084513	6	+	27260156	A375	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.1367025147378873	[864]	[895,919,1100,772]	-2	hSpCas9	negative selection	5796809
161070681	161070704	6	+	27260156	A375	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.07800302591787664	[405]	[504,596,327,392]	-1	hSpCas9	negative selection	5796810
161086391	161086414	6	+	27260156	A375	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.6578836435071074	[326]	[211,365,197,211]	-7	hSpCas9	negative selection	5861066
161070829	161070852	6	+	27260156	A375	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	0.2035227643951265	[284]	[346,352,459,368]	3	hSpCas9	negative selection	5861067
161086444	161086467	6	-	27260156	A375	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.2864109162217935	[562]	[811,1245,825,427]	4	hSpCas9	negative selection	5861068
161084596	161084619	6	+	27260156	COLO741	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.308901692762939	[338]	[565,620,431]	6	hSpCas9	negative selection	5918059
161084490	161084513	6	+	27260156	COLO741	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.497195617545336	[864]	[779,796,770]	-8	hSpCas9	negative selection	5918060
161070681	161070704	6	+	27260156	COLO741	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.39507637818742425	[405]	[298,457,415]	-7	hSpCas9	negative selection	5918061
161086391	161086414	6	+	27260156	COLO741	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.2365819874452958	[326]	[720,272,499]	5	hSpCas9	negative selection	5982317
161070829	161070852	6	+	27260156	COLO741	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.1253372594158637	[284]	[378,367,262]	-3	hSpCas9	negative selection	5982318
161086444	161086467	6	-	27260156	COLO741	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.02900325861969144	[562]	[821,755,636]	0	hSpCas9	negative selection	5982319
161084596	161084619	6	+	27260156	CAL120	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.6562173196935784	[338]	[802,829,386]	8	hSpCas9	negative selection	6039310
161084490	161084513	6	+	27260156	CAL120	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.19032567920521226	[864]	[1162,826,873]	-3	hSpCas9	negative selection	6039311
161070681	161070704	6	+	27260156	CAL120	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.13983060717199122	[405]	[477,419,479]	-2	hSpCas9	negative selection	6039312
161086391	161086414	6	+	27260156	CAL120	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.7409060577399598	[326]	[316,213,210]	-8	hSpCas9	negative selection	6103568
161070829	161070852	6	+	27260156	CAL120	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.073522745692286	[284]	[307,384,313]	-1	hSpCas9	negative selection	6103569
161086444	161086467	6	-	27260156	CAL120	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.1167233484720615	[562]	[665,755,840]	1	hSpCas9	negative selection	6103570
161084596	161084619	6	+	27260156	CADOES1	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.5205594767701973	[338]	[480,428,370,530]	8	hSpCas9	negative selection	6160561
161084490	161084513	6	+	27260156	CADOES1	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.0693232166289871	[864]	[575,854,937,695]	-1	hSpCas9	negative selection	6160562
161070681	161070704	6	+	27260156	CADOES1	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.024103928847523493	[405]	[288,361,400,435]	0	hSpCas9	negative selection	6160563
161086391	161086414	6	+	27260156	CADOES1	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.2976917769762861	[326]	[216,271,248,251]	-5	hSpCas9	negative selection	6224819
161070829	161070852	6	+	27260156	CADOES1	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.34772647216048524	[284]	[167,299,194,168]	-6	hSpCas9	negative selection	6224820
161086444	161086467	6	-	27260156	CADOES1	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.21952834067774624	[562]	[578,732,493,633]	4	hSpCas9	negative selection	6224821
161084596	161084619	6	+	27260156	EWS502	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.6743356270760291	[338]	[553,525,625,589]	9	hSpCas9	negative selection	6281812
161084490	161084513	6	+	27260156	EWS502	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.1971096625366222	[864]	[713,853,822,811]	-4	hSpCas9	negative selection	6281813
161070681	161070704	6	+	27260156	EWS502	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.3397144847805894	[405]	[719,472,376,586]	6	hSpCas9	negative selection	6281814
161086391	161086414	6	+	27260156	EWS502	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.04772646349581944	[326]	[368,383,342,329]	0	hSpCas9	negative selection	6346070
161070829	161070852	6	+	27260156	EWS502	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.22918638261693403	[284]	[222,309,222,275]	-4	hSpCas9	negative selection	6346071
161086444	161086467	6	-	27260156	EWS502	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.26177788228684984	[562]	[613,507,857,913]	4	hSpCas9	negative selection	6346072
161084596	161084619	6	+	27260156	EW8	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.2852340113562559	[338]	[317,345,288,390]	5	hSpCas9	negative selection	6403063
161084490	161084513	6	+	27260156	EW8	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.06411554587466006	[864]	[837,624,512,748]	-1	hSpCas9	negative selection	6403064
161070681	161070704	6	+	27260156	EW8	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.0492675996928382	[405]	[269,350,376,257]	-1	hSpCas9	negative selection	6403065
161086391	161086414	6	+	27260156	EW8	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.4645985945581447	[326]	[437,390,413,218]	8	hSpCas9	negative selection	6467321
161070829	161070852	6	+	27260156	EW8	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	0.07808048927747335	[284]	[291,271,154,275]	1	hSpCas9	negative selection	6467322
161086444	161086467	6	-	27260156	EW8	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.2884701965879286	[562]	[598,451,396,809]	5	hSpCas9	negative selection	6467323
161084596	161084619	6	+	27260156	CORL105	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.22143338038057642	[338]	[589,338,459,467]	4	hSpCas9	negative selection	6524314
161084490	161084513	6	+	27260156	CORL105	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.05718725953340298	[864]	[885,824,1249,974]	-1	hSpCas9	negative selection	6524315
161070681	161070704	6	+	27260156	CORL105	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.04973630221020617	[405]	[336,403,541,562]	-1	hSpCas9	negative selection	6524316
161086391	161086414	6	+	27260156	CORL105	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.10044777993578502	[326]	[507,318,309,289]	-2	hSpCas9	negative selection	6588572
161070829	161070852	6	+	27260156	CORL105	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.04263952882074351	[284]	[266,280,410,348]	-1	hSpCas9	negative selection	6588573
161086444	161086467	6	-	27260156	CORL105	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.2412891298124078	[562]	[721,832,728,820]	4	hSpCas9	negative selection	6588574
161084596	161084619	6	+	27260156	HS294T	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	1.2881019018684938	[338]	[213,492,319,243]	9	hSpCas9	negative selection	6645565
161084490	161084513	6	+	27260156	HS294T	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	0.4802887559393344	[864]	[313,683,507,345]	6	hSpCas9	negative selection	6645566
161070681	161070704	6	+	27260156	HS294T	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.3786917555723657	[405]	[231,183,261,121]	5	hSpCas9	negative selection	6645567
161086391	161086414	6	+	27260156	HS294T	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.5550709304750712	[326]	[76,60,114,93]	-7	hSpCas9	negative selection	6709823
161070829	161070852	6	+	27260156	HS294T	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	0.2150828615806345	[284]	[162,131,87,123]	3	hSpCas9	negative selection	6709824
161086444	161086467	6	-	27260156	HS294T	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.01292386337321244	[562]	[211,155,191,340]	0	hSpCas9	negative selection	6709825
161084596	161084619	6	+	27260156	HCC44	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.5956751501923714	[338]	[365,560,613,754]	8	hSpCas9	negative selection	6766816
161084490	161084513	6	+	27260156	HCC44	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.13024952933434508	[864]	[707,944,926,966]	-2	hSpCas9	negative selection	6766817
161070681	161070704	6	+	27260156	HCC44	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.22151174287444705	[405]	[407,184,353,640]	-4	hSpCas9	negative selection	6766818
161086391	161086414	6	+	27260156	HCC44	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.07336982133826697	[326]	[333,333,361,374]	-1	hSpCas9	negative selection	6831074
161070829	161070852	6	+	27260156	HCC44	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.07765662325485956	[284]	[377,346,311,187]	-1	hSpCas9	negative selection	6831075
161086444	161086467	6	-	27260156	HCC44	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.41498285552956604	[562]	[714,1121,873,637]	6	hSpCas9	negative selection	6831076
161084596	161084619	6	+	27260156	G402	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.2227159312931131	[338]	[747,312,299,590]	3	hSpCas9	negative selection	6888067
161084490	161084513	6	+	27260156	G402	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.3369368320656697	[864]	[589,390,1524,774]	-4	hSpCas9	negative selection	6888068
161070681	161070704	6	+	27260156	G402	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.6808548016022569	[405]	[488,181,325,258]	-7	hSpCas9	negative selection	6888069
161086391	161086414	6	+	27260156	G402	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.7897962807825978	[326]	[214,372,124,215]	-7	hSpCas9	negative selection	6952325
161070829	161070852	6	+	27260156	G402	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	0.30210269579842275	[284]	[897,410,166,309]	4	hSpCas9	negative selection	6952326
161086444	161086467	6	-	27260156	G402	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.6359269349490718	[562]	[1330,1022,850,1094]	7	hSpCas9	negative selection	6952327
161084596	161084619	6	+	27260156	L33	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.4718002793301828	[338]	[526,176,315,417]	8	hSpCas9	negative selection	7009318
161084490	161084513	6	+	27260156	L33	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.0821633809493435	[864]	[853,351,540,694]	-2	hSpCas9	negative selection	7009319
161070681	161070704	6	+	27260156	L33	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.20839542906595557	[405]	[460,221,301,393]	4	hSpCas9	negative selection	7009320
161086391	161086414	6	+	27260156	L33	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.077948621908287	[326]	[247,148,139,404]	-2	hSpCas9	negative selection	7073576
161070829	161070852	6	+	27260156	L33	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.11305254894747163	[284]	[268,99,196,227]	-3	hSpCas9	negative selection	7073577
161086444	161086467	6	-	27260156	L33	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.024077922399642238	[562]	[570,208,358,636]	0	hSpCas9	negative selection	7073578
161084596	161084619	6	+	27260156	K562	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	-0.05133921546290954	[338]	[211,511,204,241]	0	hSpCas9	negative selection	7130569
161084490	161084513	6	+	27260156	K562	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.4022170047164116	[864]	[692,509,434,676]	-5	hSpCas9	negative selection	7130570
161070681	161070704	6	+	27260156	K562	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.30102673715790884	[405]	[166,169,325,467]	-4	hSpCas9	negative selection	7130571
161086391	161086414	6	+	27260156	K562	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.9218865217870771	[326]	[220,134,195,73]	-8	hSpCas9	negative selection	7194827
161070829	161070852	6	+	27260156	K562	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	0.2180352403633936	[284]	[181,386,381,227]	2	hSpCas9	negative selection	7194828
161086444	161086467	6	-	27260156	K562	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.1829902527804994	[562]	[537,481,450,764]	2	hSpCas9	negative selection	7194829
161084596	161084619	6	+	27260156	HT29	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.48219319910504904	[338]	[556,626,493,617]	8	hSpCas9	negative selection	7251820
161084490	161084513	6	+	27260156	HT29	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.05895164519403817	[864]	[1218,978,1062,807]	-1	hSpCas9	negative selection	7251821
161070681	161070704	6	+	27260156	HT29	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.03246128993452471	[405]	[580,441,471,440]	0	hSpCas9	negative selection	7251822
161086391	161086414	6	+	27260156	HT29	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.14726446962280065	[326]	[364,561,400,434]	3	hSpCas9	negative selection	7316078
161070829	161070852	6	+	27260156	HT29	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.10914568959229753	[284]	[381,382,273,260]	-2	hSpCas9	negative selection	7316079
161086444	161086467	6	-	27260156	HT29	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.19076970070527022	[562]	[668,921,809,727]	4	hSpCas9	negative selection	7316080
161084596	161084619	6	+	27260156	MHHES1	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.479755100062169	[338]	[577,497,590,467]	8	hSpCas9	negative selection	7373071
161084490	161084513	6	+	27260156	MHHES1	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.03293444257797484	[864]	[1235,976,845,799]	0	hSpCas9	negative selection	7373072
161070681	161070704	6	+	27260156	MHHES1	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.16382845220802109	[405]	[262,387,638,332]	-3	hSpCas9	negative selection	7373073
161086391	161086414	6	+	27260156	MHHES1	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.07304925164887455	[326]	[293,307,420,356]	-1	hSpCas9	negative selection	7437329
161070829	161070852	6	+	27260156	MHHES1	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	0.20514721474238196	[284]	[428,440,411,235]	4	hSpCas9	negative selection	7437330
161086444	161086467	6	-	27260156	MHHES1	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	-0.04078182321067758	[562]	[634,669,706,479]	0	hSpCas9	negative selection	7437331
161084596	161084619	6	+	27260156	MEWO	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.45138738694379515	[338]	[442,372,486]	8	hSpCas9	negative selection	7494322
161084490	161084513	6	+	27260156	MEWO	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.14627254997029626	[864]	[879,599,742]	-3	hSpCas9	negative selection	7494323
161070681	161070704	6	+	27260156	MEWO	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.06898989003882086	[405]	[539,329,352]	1	hSpCas9	negative selection	7494324
161086391	161086414	6	+	27260156	MEWO	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.18156147619298624	[326]	[432,236,387]	4	hSpCas9	negative selection	7558580
161070829	161070852	6	+	27260156	MEWO	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.4397479052996701	[284]	[253,159,186]	-7	hSpCas9	negative selection	7558581
161086444	161086467	6	-	27260156	MEWO	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.1307181830917556	[562]	[799,609,362]	3	hSpCas9	negative selection	7558582
161084596	161084619	6	+	27260156	LNCAPCLONEFGC	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.6644818859679805	[338]	[378,517,549,508]	9	hSpCas9	negative selection	7615573
161084490	161084513	6	+	27260156	LNCAPCLONEFGC	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.18352044120645294	[864]	[650,623,955,572]	-3	hSpCas9	negative selection	7615574
161070681	161070704	6	+	27260156	LNCAPCLONEFGC	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.2453600031532452	[405]	[416,407,504,425]	4	hSpCas9	negative selection	7615575
161086391	161086414	6	+	27260156	LNCAPCLONEFGC	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.1509123695742352	[326]	[325,348,348,292]	2	hSpCas9	negative selection	7679831
161070829	161070852	6	+	27260156	LNCAPCLONEFGC	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.36658004187839943	[284]	[133,142,301,241]	-5	hSpCas9	negative selection	7679832
161086444	161086467	6	-	27260156	LNCAPCLONEFGC	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.4122067503399107	[562]	[716,581,699,723]	6	hSpCas9	negative selection	7679833
161084596	161084619	6	+	27260156	PANC0327	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.5707862516633458	[338]	[370,354,633,434]	8	hSpCas9	negative selection	7736824
161084490	161084513	6	+	27260156	PANC0327	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	0.013751056507504078	[864]	[779,727,679,920]	0	hSpCas9	negative selection	7736825
161070681	161070704	6	+	27260156	PANC0327	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.11143888669409122	[405]	[619,276,461,232]	1	hSpCas9	negative selection	7736826
161086391	161086414	6	+	27260156	PANC0327	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.1116897241220462	[326]	[431,287,137,409]	1	hSpCas9	negative selection	7801082
161070829	161070852	6	+	27260156	PANC0327	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.5437662120949834	[284]	[207,184,173,128]	-6	hSpCas9	negative selection	7801083
161086444	161086467	6	-	27260156	PANC0327	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.15677847785985644	[562]	[810,484,475,487]	2	hSpCas9	negative selection	7801084
161084596	161084619	6	+	27260156	NCIH2009	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.8946450392260055	[338]	[994,814,853]	9	hSpCas9	negative selection	7858075
161084490	161084513	6	+	27260156	NCIH2009	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	0.10453642703540023	[864]	[1651,1165,1149]	1	hSpCas9	negative selection	7858076
161070681	161070704	6	+	27260156	NCIH2009	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.08092221884409392	[405]	[590,525,501]	-1	hSpCas9	negative selection	7858077
161086391	161086414	6	+	27260156	NCIH2009	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.10659435175050991	[326]	[552,352,392]	-1	hSpCas9	negative selection	7922333
161070829	161070852	6	+	27260156	NCIH2009	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	0.19845890446525916	[284]	[422,470,468]	2	hSpCas9	negative selection	7922334
161086444	161086467	6	-	27260156	NCIH2009	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.06903403127965635	[562]	[1010,923,573]	0	hSpCas9	negative selection	7922335
161084596	161084619	6	+	27260156	NCIH1373	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.4674206322316269	[338]	[445,341,468,228]	4	hSpCas9	negative selection	7979326
161084490	161084513	6	+	27260156	NCIH1373	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	0.1077932498164762	[864]	[1435,1045,880,226]	1	hSpCas9	negative selection	7979327
161070681	161070704	6	+	27260156	NCIH1373	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.3782314733769504	[405]	[823,465,365,202]	4	hSpCas9	negative selection	7979328
161086391	161086414	6	+	27260156	NCIH1373	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-1.0728709373574667	[326]	[247,96,128,64]	-8	hSpCas9	negative selection	8043584
161070829	161070852	6	+	27260156	NCIH1373	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.019673743604974647	[284]	[319,585,143,45]	0	hSpCas9	negative selection	8043585
161086444	161086467	6	-	27260156	NCIH1373	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	1.0631512819966216	[562]	[976,999,1202,556]	9	hSpCas9	negative selection	8043586
161084596	161084619	6	+	27260156	PATU8902	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	1.038966680698565	[338]	[1072,743,1166,816]	9	hSpCas9	negative selection	8100577
161084490	161084513	6	+	27260156	PATU8902	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.10202651005124463	[864]	[1260,996,702,1694]	-1	hSpCas9	negative selection	8100578
161070681	161070704	6	+	27260156	PATU8902	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.16866293334477897	[405]	[589,568,302,609]	-2	hSpCas9	negative selection	8100579
161086391	161086414	6	+	27260156	PATU8902	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.09518065278934029	[326]	[178,832,249,498]	-1	hSpCas9	negative selection	8164835
161070829	161070852	6	+	27260156	PATU8902	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	0.09422516299093386	[284]	[436,623,324,318]	0	hSpCas9	negative selection	8164836
161086444	161086467	6	-	27260156	PATU8902	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.4287522303472714	[562]	[1152,1298,686,1184]	4	hSpCas9	negative selection	8164837
161084596	161084619	6	+	27260156	PANC1	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.053802231117411115	[338]	[255,360,271,323]	0	hSpCas9	negative selection	8221828
161084490	161084513	6	+	27260156	PANC1	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	0.04615950711216554	[864]	[696,1207,722,554]	0	hSpCas9	negative selection	8221829
161070681	161070704	6	+	27260156	PANC1	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.0860649454981485	[405]	[387,478,400,248]	1	hSpCas9	negative selection	8221830
161086391	161086414	6	+	27260156	PANC1	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.5491830600926708	[326]	[140,162,149,288]	-7	hSpCas9	negative selection	8286086
161070829	161070852	6	+	27260156	PANC1	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.40838274556260756	[284]	[141,347,176,113]	-6	hSpCas9	negative selection	8286087
161086444	161086467	6	-	27260156	PANC1	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	-0.03637990007078937	[562]	[458,682,534,277]	0	hSpCas9	negative selection	8286088
161084596	161084619	6	+	27260156	PANC0813	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.4725392361361974	[338]	[856,489,536,363]	7	hSpCas9	negative selection	8343079
161084490	161084513	6	+	27260156	PANC0813	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	0.08398664553160395	[864]	[1144,1091,1186,898]	1	hSpCas9	negative selection	8343080
161070681	161070704	6	+	27260156	PANC0813	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.22257888613734142	[405]	[398,493,418,325]	-4	hSpCas9	negative selection	8343081
161086391	161086414	6	+	27260156	PANC0813	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.6530961150562293	[326]	[268,223,345,145]	-7	hSpCas9	negative selection	8407337
161070829	161070852	6	+	27260156	PANC0813	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.341388841568235	[284]	[335,206,253,265]	-5	hSpCas9	negative selection	8407338
161086444	161086467	6	-	27260156	PANC0813	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	-0.159007275403605	[562]	[834,627,429,501]	-3	hSpCas9	negative selection	8407339
161084596	161084619	6	+	27260156	RDES	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.5232361973192863	[338]	[501,570,506,668]	8	hSpCas9	negative selection	8464330
161084490	161084513	6	+	27260156	RDES	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.28999370443207295	[864]	[584,886,889,931]	-5	hSpCas9	negative selection	8464331
161070681	161070704	6	+	27260156	RDES	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.39039764919321296	[405]	[313,273,367,496]	-6	hSpCas9	negative selection	8464332
161086391	161086414	6	+	27260156	RDES	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.4593968133184507	[326]	[297,174,223,410]	-7	hSpCas9	negative selection	8528588
161070829	161070852	6	+	27260156	RDES	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.25598287768408656	[284]	[268,271,228,325]	-4	hSpCas9	negative selection	8528589
161086444	161086467	6	-	27260156	RDES	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.4036388814002896	[562]	[689,739,804,1274]	6	hSpCas9	negative selection	8528590
161084596	161084619	6	+	27260156	PC3	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.5118325956837427	[338]	[423,336,959,357]	9	hSpCas9	negative selection	8585581
161084490	161084513	6	+	27260156	PC3	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.15598098117123604	[864]	[522,720,1501,660]	-4	hSpCas9	negative selection	8585582
161070681	161070704	6	+	27260156	PC3	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.1511649890084581	[405]	[240,537,751,430]	3	hSpCas9	negative selection	8585583
161086391	161086414	6	+	27260156	PC3	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.19468583224629082	[326]	[261,383,545,374]	4	hSpCas9	negative selection	8649839
161070829	161070852	6	+	27260156	PC3	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.18423351090925355	[284]	[84,266,601,239]	-4	hSpCas9	negative selection	8649840
161086444	161086467	6	-	27260156	PC3	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	-0.05213643661579001	[562]	[401,367,1110,515]	-1	hSpCas9	negative selection	8649841
161084596	161084619	6	+	27260156	PATU8988T	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.4338310334032097	[338]	[334,619,352,482]	7	hSpCas9	negative selection	8706832
161084490	161084513	6	+	27260156	PATU8988T	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.41455618728376664	[864]	[748,605,600,543]	-6	hSpCas9	negative selection	8706833
161070681	161070704	6	+	27260156	PATU8988T	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.425637250402069	[405]	[139,348,451,224]	-6	hSpCas9	negative selection	8706834
161086391	161086414	6	+	27260156	PATU8988T	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.9650489934873954	[326]	[157,190,192,102]	-8	hSpCas9	negative selection	8771090
161070829	161070852	6	+	27260156	PATU8988T	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.028491174326477964	[284]	[235,325,169,361]	0	hSpCas9	negative selection	8771091
161086444	161086467	6	-	27260156	PATU8988T	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.30686501571545377	[562]	[834,624,554,673]	5	hSpCas9	negative selection	8771092
161084596	161084619	6	+	27260156	T47D	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.4926439228674544	[338]	[562,434,659,573]	8	hSpCas9	negative selection	8828083
161084490	161084513	6	+	27260156	T47D	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.07834958829941563	[864]	[931,893,964,1033]	-2	hSpCas9	negative selection	8828084
161070681	161070704	6	+	27260156	T47D	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.06906576893874072	[405]	[483,480,551,466]	1	hSpCas9	negative selection	8828085
161086391	161086414	6	+	27260156	T47D	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.1455038214447702	[326]	[437,381,435,432]	3	hSpCas9	negative selection	8892341
161070829	161070852	6	+	27260156	T47D	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.09577591256554963	[284]	[300,213,408,325]	-2	hSpCas9	negative selection	8892342
161086444	161086467	6	-	27260156	T47D	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.19374717933792507	[562]	[753,713,804,728]	4	hSpCas9	negative selection	8892343
161084596	161084619	6	+	27260156	SU8686	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.31422070377338807	[338]	[392,428,318,546]	5	hSpCas9	negative selection	8949334
161084490	161084513	6	+	27260156	SU8686	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.0864092111460727	[864]	[701,585,939,1086]	-1	hSpCas9	negative selection	8949335
161070681	161070704	6	+	27260156	SU8686	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	0.285540011521362	[405]	[464,400,601,511]	5	hSpCas9	negative selection	8949336
161086391	161086414	6	+	27260156	SU8686	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	0.1205600567889073	[326]	[341,268,341,487]	2	hSpCas9	negative selection	9013592
161070829	161070852	6	+	27260156	SU8686	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	0.01885346444835423	[284]	[225,270,309,356]	0	hSpCas9	negative selection	9013593
161086444	161086467	6	-	27260156	SU8686	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	-0.11850601924961357	[562]	[435,395,639,626]	-2	hSpCas9	negative selection	9013594
161084596	161084619	6	+	27260156	SKES1	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.5799621730404105	[338]	[859,379,366,451]	9	hSpCas9	negative selection	9070585
161084490	161084513	6	+	27260156	SKES1	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.4010044204217663	[864]	[821,594,734,489]	-7	hSpCas9	negative selection	9070586
161070681	161070704	6	+	27260156	SKES1	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.4925258193196861	[405]	[342,232,311,263]	-8	hSpCas9	negative selection	9070587
161086391	161086414	6	+	27260156	SKES1	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.38781836832488603	[326]	[234,309,242,215]	-7	hSpCas9	negative selection	9134843
161070829	161070852	6	+	27260156	SKES1	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.44516312974640837	[284]	[172,279,163,218]	-7	hSpCas9	negative selection	9134844
161086444	161086467	6	-	27260156	SKES1	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.29600563373821653	[562]	[975,684,637,512]	6	hSpCas9	negative selection	9134845
161084596	161084619	6	+	27260156	TOV112D	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.8235141283533485	[338]	[691,670,666,402]	9	hSpCas9	negative selection	9191836
161084490	161084513	6	+	27260156	TOV112D	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.08433160902612202	[864]	[977,967,738,637]	-2	hSpCas9	negative selection	9191837
161070681	161070704	6	+	27260156	TOV112D	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.054164178637349986	[405]	[462,547,264,335]	-1	hSpCas9	negative selection	9191838
161086391	161086414	6	+	27260156	TOV112D	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.047986822269837415	[326]	[236,362,379,291]	-1	hSpCas9	negative selection	9256094
161070829	161070852	6	+	27260156	TOV112D	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.1251310680057649	[284]	[111,283,223,414]	-2	hSpCas9	negative selection	9256095
161086444	161086467	6	-	27260156	TOV112D	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	-0.11204091826552337	[562]	[390,489,400,777]	-2	hSpCas9	negative selection	9256096
161084596	161084619	6	+	27260156	TC71	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.19546222925081697	[338]	[482,405,416,352]	5	hSpCas9	negative selection	9313087
161084490	161084513	6	+	27260156	TC71	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.13038772817223376	[864]	[919,715,880,869]	-3	hSpCas9	negative selection	9313088
161070681	161070704	6	+	27260156	TC71	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.1103592821171018	[405]	[378,413,333,493]	-3	hSpCas9	negative selection	9313089
161086391	161086414	6	+	27260156	TC71	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.19457311350084872	[326]	[253,354,272,347]	-5	hSpCas9	negative selection	9377345
161070829	161070852	6	+	27260156	TC71	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.3732654180326088	[284]	[233,265,211,231]	-8	hSpCas9	negative selection	9377346
161086444	161086467	6	-	27260156	TC71	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.3239747693773275	[562]	[668,729,865,754]	7	hSpCas9	negative selection	9377347
161084596	161084619	6	+	27260156	TC32	viability	GCAGTGCTTCCGACGAAATCAGG	MAP3K4	ENSG00000085511	0.4349687405811516	[338]	[279,302,655,574]	7	hSpCas9	negative selection	9434338
161084490	161084513	6	+	27260156	TC32	viability	TGTTCCCTTAGTGACATTGCAGG	MAP3K4	ENSG00000085511	-0.19734261733771707	[864]	[715,463,881,862]	-4	hSpCas9	negative selection	9434339
161070681	161070704	6	+	27260156	TC32	viability	AGAAATGCAGTGCTGTGTCGTGG	MAP3K4	ENSG00000085511	-0.22206028809686076	[405]	[282,263,317,458]	-4	hSpCas9	negative selection	9434340
161086391	161086414	6	+	27260156	TC32	viability	AGAGATCAGTCGAGCCCTGAAGG	MAP3K4	ENSG00000085511	-0.046303761723494374	[326]	[173,298,494,250]	-1	hSpCas9	negative selection	9498596
161070829	161070852	6	+	27260156	TC32	viability	ATCTCTCTTGAGTATTAAGCAGG	MAP3K4	ENSG00000085511	-0.04451078177042278	[284]	[237,265,277,241]	-1	hSpCas9	negative selection	9498597
161086444	161086467	6	-	27260156	TC32	viability	TTTAGCAAATCCAAGTGCTTTGG	MAP3K4	ENSG00000085511	0.42721787892847485	[562]	[653,637,816,746]	7	hSpCas9	negative selection	9498598
160991965	160991988	6	-	27869803	HPAFII	viability after 27 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	-0.8746437790705577	[369]	[158,61,NaN]	-6	hSpCas9	negative selection	9594303
161034244	161034267	6	+	27869803	HPAFII	viability after 27 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	1.3796320109594784	[229]	[456,195,NaN]	9	hSpCas9	negative selection	9594308
161049724	161049747	6	-	27869803	HPAFII	viability after 27 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.3414809884756067	[576]	[457,322,NaN]	2	hSpCas9	negative selection	9594309
161070744	161070767	6	-	27869803	HPAFII	viability after 27 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	0.38353660802346473	[157]	[85,126,NaN]	3	hSpCas9	negative selection	9594310
161073478	161073501	6	+	27869803	HPAFII	viability after 27 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.18154126800440898	[301]	[193,94,NaN]	-1	hSpCas9	negative selection	9594311
161086360	161086383	6	+	27869803	HPAFII	viability after 27 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	0.636330398852668	[183]	[199,108,NaN]	5	hSpCas9	negative selection	9594312
160991965	160991988	6	-	27869803	HPAFII	viability after 15 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	-0.32313021031240463	[369]	[196,392,NaN]	-4	hSpCas9	negative selection	9676752
161034244	161034267	6	+	27869803	HPAFII	viability after 15 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	1.2821384990292615	[229]	[869,433,NaN]	9	hSpCas9	negative selection	9676757
161049724	161049747	6	-	27869803	HPAFII	viability after 15 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.4026399486928882	[576]	[1177,596,NaN]	4	hSpCas9	negative selection	9676758
161070744	161070767	6	-	27869803	HPAFII	viability after 15 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	-0.7648167493217941	[157]	[131,79,NaN]	-7	hSpCas9	negative selection	9676759
161073478	161073501	6	+	27869803	HPAFII	viability after 15 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.13780101789481153	[301]	[694,146,NaN]	1	hSpCas9	negative selection	9676760
161086360	161086383	6	+	27869803	HPAFII	viability after 15 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	-0.11243545506457553	[183]	[259,134,NaN]	-1	hSpCas9	negative selection	9676761
160991965	160991988	6	-	27869803	ASPC1	viability after 36 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.2811511177172527	[744]	[631,213,171]	3	hSpCas9	negative selection	9759201
161034244	161034267	6	+	27869803	ASPC1	viability after 36 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.8118434902275299	[933]	[444,974,335]	7	hSpCas9	negative selection	9759206
161049724	161049747	6	-	27869803	ASPC1	viability after 36 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.7026554986063822	[1152]	[487,366,993]	7	hSpCas9	negative selection	9759207
161070744	161070767	6	-	27869803	ASPC1	viability after 36 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	-1.0416034845674216	[335]	[44,62,59]	-7	hSpCas9	negative selection	9759208
161073478	161073501	6	+	27869803	ASPC1	viability after 36 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.3261856623153077	[969]	[101,297,362]	-3	hSpCas9	negative selection	9759209
161086360	161086383	6	+	27869803	ASPC1	viability after 36 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	-0.3280972885439839	[423]	[207,154,23]	-3	hSpCas9	negative selection	9759210
160991965	160991988	6	-	27869803	PATU8988S	viability after 35 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.44118925830749106	[739]	[469,338,NaN]	5	hSpCas9	negative selection	9841650
161034244	161034267	6	+	27869803	PATU8988S	viability after 35 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.08323351830949555	[772]	[248,410,NaN]	1	hSpCas9	negative selection	9841655
161049724	161049747	6	-	27869803	PATU8988S	viability after 35 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.7159036379811371	[984]	[694,607,NaN]	7	hSpCas9	negative selection	9841656
161070744	161070767	6	-	27869803	PATU8988S	viability after 35 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	1.1702288648686596	[320]	[267,313,NaN]	9	hSpCas9	negative selection	9841657
161073478	161073501	6	+	27869803	PATU8988S	viability after 35 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.0238005265406232	[766]	[334,292,NaN]	0	hSpCas9	negative selection	9841658
161086360	161086383	6	+	27869803	PATU8988S	viability after 35 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	0.4629373857160461	[381]	[237,185,NaN]	5	hSpCas9	negative selection	9841659
160991965	160991988	6	-	27869803	PATU8988S	viability after 31 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	0.3747565629481568	[739]	[353,418,NaN]	4	hSpCas9	negative selection	9924099
161034244	161034267	6	+	27869803	PATU8988S	viability after 31 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	0.008024254320049273	[772]	[250,384,NaN]	0	hSpCas9	negative selection	9924104
161049724	161049747	6	-	27869803	PATU8988S	viability after 31 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.7516369904280321	[984]	[538,816,NaN]	8	hSpCas9	negative selection	9924105
161070744	161070767	6	-	27869803	PATU8988S	viability after 31 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	1.1395774559091925	[320]	[270,295,NaN]	9	hSpCas9	negative selection	9924106
161073478	161073501	6	+	27869803	PATU8988S	viability after 31 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.2892226512362395	[766]	[244,256,NaN]	-3	hSpCas9	negative selection	9924107
161086360	161086383	6	+	27869803	PATU8988S	viability after 31 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	0.35102386207773006	[381]	[188,200,NaN]	4	hSpCas9	negative selection	9924108
160991965	160991988	6	-	27869803	HPAFII	viability after 35 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	-1.3069283957594338	[369]	[78,71,NaN]	-6	hSpCas9	negative selection	10006548
161034244	161034267	6	+	27869803	HPAFII	viability after 35 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	1.3250163159272499	[229]	[310,269,NaN]	8	hSpCas9	negative selection	10006553
161049724	161049747	6	-	27869803	HPAFII	viability after 35 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.4468586517923345	[576]	[360,439,NaN]	3	hSpCas9	negative selection	10006554
161070744	161070767	6	-	27869803	HPAFII	viability after 35 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	0.4378342017865612	[157]	[97,119,NaN]	3	hSpCas9	negative selection	10006555
161073478	161073501	6	+	27869803	HPAFII	viability after 35 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.46559353558910954	[301]	[331,74,NaN]	3	hSpCas9	negative selection	10006556
161086360	161086383	6	+	27869803	HPAFII	viability after 35 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	-0.19747580285383093	[183]	[76,85,NaN]	-1	hSpCas9	negative selection	10006557
160991965	160991988	6	-	27869803	HPAFII	viability after 31 days	GCAGGCGTGACGGCAAAGGCGGG	MAP3K4	ENSG00000085511	-0.7076226090383106	[369]	[163,86,NaN]	-4	hSpCas9	negative selection	10088997
161034244	161034267	6	+	27869803	HPAFII	viability after 31 days	CACTGTCTTTCATAGGCAAGAGG	MAP3K4	ENSG00000085511	1.2233483731666122	[229]	[309,291,NaN]	8	hSpCas9	negative selection	10089002
161049724	161049747	6	-	27869803	HPAFII	viability after 31 days	TGGATATGCAGTCCCGCGACTGG	MAP3K4	ENSG00000085511	0.4785441093431868	[576]	[488,409,NaN]	3	hSpCas9	negative selection	10089003
161070744	161070767	6	-	27869803	HPAFII	viability after 31 days	GACTCGGCAGAGAACTAGGAAGG	MAP3K4	ENSG00000085511	0.37328722061947917	[157]	[133,93,NaN]	2	hSpCas9	negative selection	10089004
161073478	161073501	6	+	27869803	HPAFII	viability after 31 days	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.3777775068092152	[301]	[280,153,NaN]	2	hSpCas9	negative selection	10089005
161086360	161086383	6	+	27869803	HPAFII	viability after 31 days	ACTTGAATCCACTTGGCAGGAGG	MAP3K4	ENSG00000085511	0.3094066497713769	[183]	[182,67,NaN]	2	hSpCas9	negative selection	10089006
160992034	160992057	6	-	28162770	P31FUJ	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.5554607534347736	[325]	[562]	6	hSpCas9	negative selection	10188814
160991962	160991985	6	-	28162770	P31FUJ	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	-0.3637330742408273	[218]	[199]	-3	hSpCas9	negative selection	10188815
161073478	161073501	6	+	28162770	P31FUJ	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.1661873536325954	[112]	[148]	1	hSpCas9	negative selection	10188816
161080989	161081012	6	+	28162770	P31FUJ	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.7200111101411791	[201]	[390]	8	hSpCas9	negative selection	10188817
161097141	161097164	6	-	28162770	P31FUJ	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	-0.44765307673820737	[158]	[136]	-4	hSpCas9	negative selection	10188818
161101961	161101984	6	+	28162770	P31FUJ	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	0.38190763970082936	[191]	[293]	4	hSpCas9	negative selection	10188819
161102695	161102718	6	+	28162770	P31FUJ	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.8902561919899596	[364]	[794]	8	hSpCas9	negative selection	10188820
161109898	161109921	6	-	28162770	P31FUJ	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	0.6288865672101912	[267]	[486]	7	hSpCas9	negative selection	10188821
161111929	161111952	6	+	28162770	P31FUJ	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.21599391672782486	[511]	[517]	-2	hSpCas9	negative selection	10188822
161115244	161115267	6	+	28162770	P31FUJ	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	0.2903651953593357	[317]	[456]	3	hSpCas9	negative selection	10188823
160992034	160992057	6	-	28162770	TF1	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10358180
160991962	160991985	6	-	28162770	TF1	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10358181
161073478	161073501	6	+	28162770	TF1	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	NaN	[NaN]	[25]	1	hSpCas9	negative selection	10358182
161080989	161081012	6	+	28162770	TF1	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	NaN	[NaN]	[159]	1	hSpCas9	negative selection	10358183
161097141	161097164	6	-	28162770	TF1	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10358184
161101961	161101984	6	+	28162770	TF1	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	NaN	[NaN]	[126]	1	hSpCas9	negative selection	10358185
161102695	161102718	6	+	28162770	TF1	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	NaN	[NaN]	[92]	1	hSpCas9	negative selection	10358186
161109898	161109921	6	-	28162770	TF1	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10358187
161111929	161111952	6	+	28162770	TF1	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	NaN	[NaN]	[198]	1	hSpCas9	negative selection	10358188
161115244	161115267	6	+	28162770	TF1	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10358189
160992034	160992057	6	-	28162770	SKM1	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	-0.02404547396665102	[87]	[152]	0	hSpCas9	negative selection	10527546
160991962	160991985	6	-	28162770	SKM1	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	-0.0783414512817911	[42]	[71]	0	hSpCas9	negative selection	10527547
161073478	161073501	6	+	28162770	SKM1	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.8744691179161412	[27]	[26]	-6	hSpCas9	negative selection	10527548
161080989	161081012	6	+	28162770	SKM1	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.9520622385863785	[57]	[52]	-6	hSpCas9	negative selection	10527549
161097141	161097164	6	-	28162770	SKM1	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	-0.18457177740671382	[35]	[55]	-1	hSpCas9	negative selection	10527550
161101961	161101984	6	+	28162770	SKM1	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	0.1779983019779945	[46]	[93]	1	hSpCas9	negative selection	10527551
161102695	161102718	6	+	28162770	SKM1	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.12141477361162678	[64]	[124]	1	hSpCas9	negative selection	10527552
161109898	161109921	6	-	28162770	SKM1	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	0.4798886436288117	[57]	[142]	4	hSpCas9	negative selection	10527553
161111929	161111952	6	+	28162770	SKM1	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.779773462632708	[100]	[103]	-5	hSpCas9	negative selection	10527554
161115244	161115267	6	+	28162770	SKM1	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	-0.1554254317471972	[62]	[99]	-1	hSpCas9	negative selection	10527555
160992034	160992057	6	-	28162770	SKM1	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	-0.02404547396665102	[87]	[152]	0	hSpCas9	negative selection	10696912
160991962	160991985	6	-	28162770	SKM1	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	-0.0783414512817911	[42]	[71]	0	hSpCas9	negative selection	10696913
161073478	161073501	6	+	28162770	SKM1	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.8744691179161412	[27]	[26]	-6	hSpCas9	negative selection	10696914
161080989	161081012	6	+	28162770	SKM1	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.9520622385863785	[57]	[52]	-6	hSpCas9	negative selection	10696915
161097141	161097164	6	-	28162770	SKM1	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	-0.18457177740671382	[35]	[55]	-1	hSpCas9	negative selection	10696916
161101961	161101984	6	+	28162770	SKM1	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	0.1779983019779945	[46]	[93]	1	hSpCas9	negative selection	10696917
161102695	161102718	6	+	28162770	SKM1	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.12141477361162678	[64]	[124]	1	hSpCas9	negative selection	10696918
161109898	161109921	6	-	28162770	SKM1	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	0.4798886436288117	[57]	[142]	4	hSpCas9	negative selection	10696919
161111929	161111952	6	+	28162770	SKM1	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.779773462632708	[100]	[103]	-5	hSpCas9	negative selection	10696920
161115244	161115267	6	+	28162770	SKM1	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	-0.1554254317471972	[62]	[99]	-1	hSpCas9	negative selection	10696921
160992034	160992057	6	-	28162770	PL21	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	-0.08490341227823328	[250]	[102]	0	hSpCas9	negative selection	10866278
160991962	160991985	6	-	28162770	PL21	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	-0.4588234676756129	[119]	[37]	-3	hSpCas9	negative selection	10866279
161073478	161073501	6	+	28162770	PL21	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.8670133129970937	[96]	[76]	7	hSpCas9	negative selection	10866280
161080989	161081012	6	+	28162770	PL21	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-1.070389327891398	[192]	[39]	-6	hSpCas9	negative selection	10866281
161097141	161097164	6	-	28162770	PL21	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	-0.7998603855106798	[179]	[44]	-5	hSpCas9	negative selection	10866282
161101961	161101984	6	+	28162770	PL21	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	0.5779442075691886	[156]	[101]	5	hSpCas9	negative selection	10866283
161102695	161102718	6	+	28162770	PL21	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.11034294413867435	[231]	[108]	1	hSpCas9	negative selection	10866284
161109898	161109921	6	-	28162770	PL21	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	-0.4256951676473641	[178]	[57]	-3	hSpCas9	negative selection	10866285
161111929	161111952	6	+	28162770	PL21	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.5486756975546299	[325]	[96]	-4	hSpCas9	negative selection	10866286
161115244	161115267	6	+	28162770	PL21	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	0.07559451655101679	[265]	[121]	0	hSpCas9	negative selection	10866287
160992034	160992057	6	-	28162770	P31FUJ	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.5554607534347736	[325]	[562]	6	hSpCas9	negative selection	11035644
160991962	160991985	6	-	28162770	P31FUJ	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	-0.3637330742408273	[218]	[199]	-3	hSpCas9	negative selection	11035645
161073478	161073501	6	+	28162770	P31FUJ	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.1661873536325954	[112]	[148]	1	hSpCas9	negative selection	11035646
161080989	161081012	6	+	28162770	P31FUJ	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.7200111101411791	[201]	[390]	8	hSpCas9	negative selection	11035647
161097141	161097164	6	-	28162770	P31FUJ	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	-0.44765307673820737	[158]	[136]	-4	hSpCas9	negative selection	11035648
161101961	161101984	6	+	28162770	P31FUJ	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	0.38190763970082936	[191]	[293]	4	hSpCas9	negative selection	11035649
161102695	161102718	6	+	28162770	P31FUJ	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.8902561919899596	[364]	[794]	8	hSpCas9	negative selection	11035650
161109898	161109921	6	-	28162770	P31FUJ	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	0.6288865672101912	[267]	[486]	7	hSpCas9	negative selection	11035651
161111929	161111952	6	+	28162770	P31FUJ	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.21599391672782486	[511]	[517]	-2	hSpCas9	negative selection	11035652
161115244	161115267	6	+	28162770	P31FUJ	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	0.2903651953593357	[317]	[456]	3	hSpCas9	negative selection	11035653
160992034	160992057	6	-	28162770	OCIAML5	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.5277424401038655	[170]	[444]	4	hSpCas9	negative selection	11205010
160991962	160991985	6	-	28162770	OCIAML5	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	-0.4800977934770391	[135]	[175]	-3	hSpCas9	negative selection	11205011
161073478	161073501	6	+	28162770	OCIAML5	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.8000101257156962	[34]	[109]	7	hSpCas9	negative selection	11205012
161080989	161081012	6	+	28162770	OCIAML5	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.2702099810106625	[154]	[231]	-2	hSpCas9	negative selection	11205013
161097141	161097164	6	-	28162770	OCIAML5	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	0.5662460604477078	[54]	[146]	5	hSpCas9	negative selection	11205014
161101961	161101984	6	+	28162770	OCIAML5	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	0.8920945247064132	[79]	[267]	7	hSpCas9	negative selection	11205015
161102695	161102718	6	+	28162770	OCIAML5	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.08114633792480086	[209]	[400]	0	hSpCas9	negative selection	11205016
161109898	161109921	6	-	28162770	OCIAML5	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	0.13055135090776648	[166]	[329]	1	hSpCas9	negative selection	11205017
161111929	161111952	6	+	28162770	OCIAML5	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	0.011023484921653948	[242]	[441]	0	hSpCas9	negative selection	11205018
161115244	161115267	6	+	28162770	OCIAML5	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	0.31527063608915973	[247]	[556]	2	hSpCas9	negative selection	11205019
160992034	160992057	6	-	28162770	EOL1	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.38257848861768884	[561]	[385]	3	hSpCas9	negative selection	11374376
160991962	160991985	6	-	28162770	EOL1	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	-0.19744275280807577	[147]	[67]	-1	hSpCas9	negative selection	11374377
161073478	161073501	6	+	28162770	EOL1	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.20551276899383847	[231]	[105]	-1	hSpCas9	negative selection	11374378
161080989	161081012	6	+	28162770	EOL1	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.8226861580494987	[328]	[97]	-5	hSpCas9	negative selection	11374379
161097141	161097164	6	-	28162770	EOL1	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	0.19373440438592365	[233]	[140]	1	hSpCas9	negative selection	11374380
161101961	161101984	6	+	28162770	EOL1	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	-0.20138921749444044	[322]	[147]	-1	hSpCas9	negative selection	11374381
161102695	161102718	6	+	28162770	EOL1	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.42933992360770734	[295]	[209]	4	hSpCas9	negative selection	11374382
161109898	161109921	6	-	28162770	EOL1	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	1.28886551324151	[274]	[353]	9	hSpCas9	negative selection	11374383
161111929	161111952	6	+	28162770	EOL1	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.12338670549316749	[458]	[221]	-1	hSpCas9	negative selection	11374384
161115244	161115267	6	+	28162770	EOL1	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	0.14629396891369661	[318]	[185]	1	hSpCas9	negative selection	11374385
160992034	160992057	6	-	28162770	MOLM13	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.26843377148528974	[363]	[316]	2	hSpCas9	negative selection	11543742
160991962	160991985	6	-	28162770	MOLM13	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	0.024282730068964198	[203]	[149]	0	hSpCas9	negative selection	11543743
161073478	161073501	6	+	28162770	MOLM13	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.29670273153835514	[142]	[126]	2	hSpCas9	negative selection	11543744
161080989	161081012	6	+	28162770	MOLM13	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.6364472782701568	[343]	[159]	-4	hSpCas9	negative selection	11543745
161097141	161097164	6	-	28162770	MOLM13	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	0.02846772363877581	[178]	[131]	0	hSpCas9	negative selection	11543746
161101961	161101984	6	+	28162770	MOLM13	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	-0.19554717719966208	[254]	[160]	-1	hSpCas9	negative selection	11543747
161102695	161102718	6	+	28162770	MOLM13	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.2302595209638763	[348]	[295]	1	hSpCas9	negative selection	11543748
161109898	161109921	6	-	28162770	MOLM13	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	-0.8268538840165531	[367]	[149]	-4	hSpCas9	negative selection	11543749
161111929	161111952	6	+	28162770	MOLM13	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.5928646495345175	[387]	[185]	-3	hSpCas9	negative selection	11543750
161115244	161115267	6	+	28162770	MOLM13	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	-0.46357923678460566	[554]	[290]	-3	hSpCas9	negative selection	11543751
160992034	160992057	6	-	28162770	HEL	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.27383987090081297	[358]	[277]	2	hSpCas9	negative selection	11713108
160991962	160991985	6	-	28162770	HEL	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	-0.5142305143380423	[193]	[86]	-3	hSpCas9	negative selection	11713109
161073478	161073501	6	+	28162770	HEL	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.6205430858861609	[130]	[128]	5	hSpCas9	negative selection	11713110
161080989	161081012	6	+	28162770	HEL	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.19878857922503537	[266]	[148]	-1	hSpCas9	negative selection	11713111
161097141	161097164	6	-	28162770	HEL	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	-0.0942267621658493	[199]	[119]	0	hSpCas9	negative selection	11713112
161101961	161101984	6	+	28162770	HEL	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	-0.2670633590280648	[247]	[131]	-2	hSpCas9	negative selection	11713113
161102695	161102718	6	+	28162770	HEL	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.14818099307798682	[316]	[224]	1	hSpCas9	negative selection	11713114
161109898	161109921	6	-	28162770	HEL	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	-0.6653834633619748	[311]	[125]	-4	hSpCas9	negative selection	11713115
161111929	161111952	6	+	28162770	HEL	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-1.572858027827238	[352]	[75]	-7	hSpCas9	negative selection	11713116
161115244	161115267	6	+	28162770	HEL	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	-0.32555230827230497	[404]	[206]	-2	hSpCas9	negative selection	11713117
160992034	160992057	6	-	28162770	MV411	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.6330912432805249	[247]	[323]	6	hSpCas9	negative selection	11882474
160991962	160991985	6	-	28162770	MV411	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	0.7554380696890473	[153]	[218]	6	hSpCas9	negative selection	11882475
161073478	161073501	6	+	28162770	MV411	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.12005824430654788	[70]	[64]	1	hSpCas9	negative selection	11882476
161080989	161081012	6	+	28162770	MV411	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.14388387952226095	[180]	[137]	-1	hSpCas9	negative selection	11882477
161097141	161097164	6	-	28162770	MV411	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	1.3178268786741731	[99]	[209]	9	hSpCas9	negative selection	11882478
161101961	161101984	6	+	28162770	MV411	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	-0.2968829654410348	[209]	[143]	-2	hSpCas9	negative selection	11882479
161102695	161102718	6	+	28162770	MV411	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.573140689361519	[228]	[286]	5	hSpCas9	negative selection	11882480
161109898	161109921	6	-	28162770	MV411	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	-0.14804715107466804	[170]	[129]	-1	hSpCas9	negative selection	11882481
161111929	161111952	6	+	28162770	MV411	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.6899314609468209	[292]	[152]	-5	hSpCas9	negative selection	11882482
161115244	161115267	6	+	28162770	MV411	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	-0.4196260301532746	[234]	[147]	-3	hSpCas9	negative selection	11882483
160992034	160992057	6	-	28162770	MONOMAC1	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	-0.6178799680196032	[165]	[123]	-5	hSpCas9	negative selection	12051840
160991962	160991985	6	-	28162770	MONOMAC1	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	0.9220158245842098	[92]	[201]	8	hSpCas9	negative selection	12051841
161073478	161073501	6	+	28162770	MONOMAC1	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.5414823785083436	[112]	[88]	-4	hSpCas9	negative selection	12051842
161080989	161081012	6	+	28162770	MONOMAC1	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-1.039935885974825	[112]	[62]	-7	hSpCas9	negative selection	12051843
161097141	161097164	6	-	28162770	MONOMAC1	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	0.4024252233567175	[98]	[149]	4	hSpCas9	negative selection	12051844
161101961	161101984	6	+	28162770	MONOMAC1	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	-1.5358387605113122	[128]	[50]	-8	hSpCas9	negative selection	12051845
161102695	161102718	6	+	28162770	MONOMAC1	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	0.01813124750898157	[142]	[165]	0	hSpCas9	negative selection	12051846
161109898	161109921	6	-	28162770	MONOMAC1	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	-0.3814614181969812	[124]	[109]	-3	hSpCas9	negative selection	12051847
161111929	161111952	6	+	28162770	MONOMAC1	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.5380737648946207	[189]	[149]	-4	hSpCas9	negative selection	12051848
161115244	161115267	6	+	28162770	MONOMAC1	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	0.44525882872755396	[147]	[230]	4	hSpCas9	negative selection	12051849
160992034	160992057	6	-	28162770	OCIAML2	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.20242400510385178	[44]	[286]	2	hSpCas9	negative selection	12221206
160991962	160991985	6	-	28162770	OCIAML2	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	-0.2847632799308273	[19]	[90]	-2	hSpCas9	negative selection	12221207
161073478	161073501	6	+	28162770	OCIAML2	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	0.18281241336176152	[23]	[150]	1	hSpCas9	negative selection	12221208
161080989	161081012	6	+	28162770	OCIAML2	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	0.7414206518728278	[29]	[277]	7	hSpCas9	negative selection	12221209
161097141	161097164	6	-	28162770	OCIAML2	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	-0.32767187140011833	[23]	[105]	-3	hSpCas9	negative selection	12221210
161101961	161101984	6	+	28162770	OCIAML2	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	-0.3621053684639921	[31]	[137]	-3	hSpCas9	negative selection	12221211
161102695	161102718	6	+	28162770	OCIAML2	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	-0.10060744215375383	[58]	[304]	-1	hSpCas9	negative selection	12221212
161109898	161109921	6	-	28162770	OCIAML2	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	-0.43500591551143986	[29]	[122]	-3	hSpCas9	negative selection	12221213
161111929	161111952	6	+	28162770	OCIAML2	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.41050883280459033	[46]	[195]	-3	hSpCas9	negative selection	12221214
161115244	161115267	6	+	28162770	OCIAML2	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	0.7790624529974897	[42]	[408]	7	hSpCas9	negative selection	12221215
160992034	160992057	6	-	28162770	OCIAML3	viability	GACTCGGTCTCGGGTTCCGGTGG	MAP3K4	ENSG00000085511	0.24811269989411744	[81]	[293]	2	hSpCas9	negative selection	12390572
160991962	160991985	6	-	28162770	OCIAML3	viability	GGCGTGACGGCAAAGGCGGGAGG	MAP3K4	ENSG00000085511	0.7692908889830596	[54]	[282]	7	hSpCas9	negative selection	12390573
161073478	161073501	6	+	28162770	OCIAML3	viability	TGTAAGGAGGTCCTGAAGGGCGG	MAP3K4	ENSG00000085511	-0.3341405135690524	[37]	[90]	-3	hSpCas9	negative selection	12390574
161080989	161081012	6	+	28162770	OCIAML3	viability	ATAACTCATTACATACGGGGAGG	MAP3K4	ENSG00000085511	-0.0485735037896442	[36]	[107]	0	hSpCas9	negative selection	12390575
161097141	161097164	6	-	28162770	OCIAML3	viability	GAGTGGGGATAATGAGGTGTGGG	MAP3K4	ENSG00000085511	-0.48211476025326583	[30]	[66]	-4	hSpCas9	negative selection	12390576
161101961	161101984	6	+	28162770	OCIAML3	viability	TCGTCACTCAAGCCCCACGGAGG	MAP3K4	ENSG00000085511	-0.9043477609363137	[61]	[99]	-6	hSpCas9	negative selection	12390577
161102695	161102718	6	+	28162770	OCIAML3	viability	GCAGAACCAGCATATCCAAGAGG	MAP3K4	ENSG00000085511	-0.3524810520310001	[106]	[252]	-3	hSpCas9	negative selection	12390578
161109898	161109921	6	-	28162770	OCIAML3	viability	GATTACCTTTAATGTCACGGTGG	MAP3K4	ENSG00000085511	0.4322716844746857	[67]	[276]	4	hSpCas9	negative selection	12390579
161111929	161111952	6	+	28162770	OCIAML3	viability	GTGAAGTGAACAGCACCCTGGGG	MAP3K4	ENSG00000085511	-0.6438835469637328	[102]	[198]	-5	hSpCas9	negative selection	12390580
161115244	161115267	6	+	28162770	OCIAML3	viability	AGAGTGACCCAAAGATGAGATGG	MAP3K4	ENSG00000085511	0.5936193628516082	[62]	[286]	5	hSpCas9	negative selection	12390581