Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1326
• Symbol:MAP3K8
• Description:mitogen-activated protein kinase kinase kinase 8

DataSource: http://genomecrispr.dkfz.de/#!/results/MAP3K8

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
30438936	30438959	10	+	26472758	Jiyoye	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.20991367549310747	[312]	[272]	1	hSpCas9	negative selection	96073
30450399	30450422	10	+	26472758	Jiyoye	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	0.2372503800635608	[44]	[39]	1	hSpCas9	negative selection	96074
30458096	30458119	10	+	26472758	Jiyoye	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	1.3010098242889456	[147]	[274]	7	hSpCas9	negative selection	96075
30458181	30458204	10	-	26472758	Jiyoye	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	1.2145303035634776	[67]	[118]	7	hSpCas9	negative selection	96076
30458203	30458226	10	-	26472758	Jiyoye	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	1.0269033003877064	[40]	[62]	6	hSpCas9	negative selection	96077
30459440	30459463	10	-	26472758	Jiyoye	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	1.4892764617207672	[110]	[234]	8	hSpCas9	negative selection	96078
30439132	30439155	10	+	26472758	Jiyoye	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	1.5283118190075082	[136]	[297]	8	hSpCas9	negative selection	96079
30451723	30451746	10	+	26472758	Jiyoye	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.9921378822270293	[3]	[5]	6	hSpCas9	negative selection	96080
30459414	30459437	10	-	26472758	Jiyoye	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	-0.24490131507381974	[219]	[139]	-2	hSpCas9	negative selection	96081
30459458	30459481	10	+	26472758	Jiyoye	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	-0.44082152504907657	[116]	[64]	-3	hSpCas9	negative selection	96082
30438936	30438959	10	+	26472758	KBM7	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.8639461758343794	[1088,1321]	[1342,781]	8	hSpCas9	negative selection	287191
30450399	30450422	10	+	26472758	KBM7	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	0.018535281669542325	[64,52]	[28,26]	0	hSpCas9	negative selection	287192
30458096	30458119	10	+	26472758	KBM7	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	-0.24346320784359055	[978,643]	[277,351]	-2	hSpCas9	negative selection	287193
30458181	30458204	10	-	26472758	KBM7	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	-0.13256911792432452	[589,455]	[307,145]	-1	hSpCas9	negative selection	287194
30458203	30458226	10	-	26472758	KBM7	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	0.06535936488628025	[231,117]	[61,102]	0	hSpCas9	negative selection	287195
30459440	30459463	10	-	26472758	KBM7	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.314106489524012	[1217,783]	[621,532]	3	hSpCas9	negative selection	287196
30439132	30439155	10	+	26472758	KBM7	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.6572983113143818	[1004,957]	[812,654]	7	hSpCas9	negative selection	287197
30451723	30451746	10	+	26472758	KBM7	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	-0.29707634212221157	[56,111]	[69,0]	-3	hSpCas9	negative selection	287198
30459414	30459437	10	-	26472758	KBM7	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.513370637325404	[713,860]	[391,664]	5	hSpCas9	negative selection	287199
30459458	30459481	10	+	26472758	KBM7	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	0.39806187980805846	[461,469]	[386,203]	4	hSpCas9	negative selection	287200
30438936	30438959	10	+	26472758	Raji	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.9712834115795532	[410]	[186]	8	hSpCas9	negative selection	478309
30450399	30450422	10	+	26472758	Raji	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-2.517107329534195	[73]	[2]	-9	hSpCas9	negative selection	478310
30458096	30458119	10	+	26472758	Raji	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	-0.4805082963862283	[492]	[81]	-4	hSpCas9	negative selection	478311
30458181	30458204	10	-	26472758	Raji	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	-0.3451286693239072	[207]	[37]	-3	hSpCas9	negative selection	478312
30458203	30458226	10	-	26472758	Raji	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	1.0264635399900321	[54]	[25]	8	hSpCas9	negative selection	478313
30459440	30459463	10	-	26472758	Raji	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	1.2373138394187335	[381]	[208]	9	hSpCas9	negative selection	478314
30439132	30439155	10	+	26472758	Raji	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.5116142796958605	[401]	[132]	5	hSpCas9	negative selection	478315
30451723	30451746	10	+	26472758	Raji	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.4375321370659304	[69]	[21]	4	hSpCas9	negative selection	478316
30459414	30459437	10	-	26472758	Raji	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.3606699646558311	[395]	[117]	3	hSpCas9	negative selection	478317
30459458	30459481	10	+	26472758	Raji	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	-1.9800793058767399	[237]	[13]	-8	hSpCas9	negative selection	478318
30438936	30438959	10	+	26472758	K562	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.498126689469103	[956]	[1140]	4	hSpCas9	negative selection	669427
30450399	30450422	10	+	26472758	K562	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-7.156460708615737	[168]	[0]	-9	hSpCas9	negative selection	669428
30458096	30458119	10	+	26472758	K562	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	0.2404056651598233	[719]	[717]	1	hSpCas9	negative selection	669429
30458181	30458204	10	-	26472758	K562	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	0.9357874553925424	[404]	[653]	7	hSpCas9	negative selection	669430
30458203	30458226	10	-	26472758	K562	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	0.4120186761625153	[137]	[154]	3	hSpCas9	negative selection	669431
30459440	30459463	10	-	26472758	K562	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.1286880911464784	[745]	[575]	-1	hSpCas9	negative selection	669432
30439132	30439155	10	+	26472758	K562	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.64561430179166	[863]	[1140]	5	hSpCas9	negative selection	669433
30451723	30451746	10	+	26472758	K562	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.3017519027323985	[73]	[76]	2	hSpCas9	negative selection	669434
30459414	30459437	10	-	26472758	K562	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	-0.38808333093932207	[616]	[397]	-3	hSpCas9	negative selection	669435
30459458	30459481	10	+	26472758	K562	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	1.1317047653354542	[325]	[602]	8	hSpCas9	negative selection	669436
30439124	30439147	10	+	26627737	DLD1	viability	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.2799744375237643	[724]	[316,297,219]	3	hSpCas9	negative selection	774768
30450296	30450319	10	-	26627737	DLD1	viability	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	-0.09821935827537392	[422]	[186,70,111]	-1	hSpCas9	negative selection	774769
30450365	30450388	10	+	26627737	DLD1	viability	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	0.8154810778507804	[152]	[58,123,72]	7	hSpCas9	negative selection	774770
30451723	30451746	10	+	26627737	DLD1	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.18490736798080018	[349]	[127,213,46]	2	hSpCas9	negative selection	774771
30458154	30458177	10	-	26627737	DLD1	viability	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.885867072591455	[751]	[413,588,323]	8	hSpCas9	negative selection	774772
30459440	30459463	10	-	26627737	DLD1	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.1671149973319039	[367]	[230,122,45]	1	hSpCas9	negative selection	774773
30439124	30439147	10	+	26627737	GBM cells	viability after 5 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.19480410887152466	[368]	[236,215]	3	hSpCas9	negative selection	857083
30450296	30450319	10	-	26627737	GBM cells	viability after 5 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	1.43594189854314	[101]	[138,156]	9	hSpCas9	negative selection	857084
30450365	30450388	10	+	26627737	GBM cells	viability after 5 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	0.9957754141382746	[107]	[99,130]	9	hSpCas9	negative selection	857085
30451723	30451746	10	+	26627737	GBM cells	viability after 5 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.13374339946035627	[197]	[102,129]	2	hSpCas9	negative selection	857086
30458154	30458177	10	-	26627737	GBM cells	viability after 5 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.4130361350563931	[319]	[235,220]	6	hSpCas9	negative selection	857087
30459440	30459463	10	-	26627737	GBM cells	viability after 5 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.3506057244736265	[169]	[82,59]	-5	hSpCas9	negative selection	857088
30439124	30439147	10	+	26627737	GBM cells	viability after 13 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.3512242182177471	[368]	[293,223]	4	hSpCas9	negative selection	939398
30450296	30450319	10	-	26627737	GBM cells	viability after 13 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	1.794806023616232	[101]	[164,213]	9	hSpCas9	negative selection	939399
30450365	30450388	10	+	26627737	GBM cells	viability after 13 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	1.1066828490287366	[107]	[166,92]	9	hSpCas9	negative selection	939400
30451723	30451746	10	+	26627737	GBM cells	viability after 13 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.23288608113799494	[197]	[144,110]	3	hSpCas9	negative selection	939401
30458154	30458177	10	-	26627737	GBM cells	viability after 13 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.7014181629835721	[319]	[401,184]	8	hSpCas9	negative selection	939402
30459440	30459463	10	-	26627737	GBM cells	viability after 13 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.39921765406393783	[169]	[91,51]	-5	hSpCas9	negative selection	939403
30439124	30439147	10	+	26627737	GBM cells	viability after 21 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.44175059581835807	[368]	[288,256]	4	hSpCas9	negative selection	1021713
30450296	30450319	10	-	26627737	GBM cells	viability after 21 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	1.7976879366184553	[101]	[188,195]	9	hSpCas9	negative selection	1021714
30450365	30450388	10	+	26627737	GBM cells	viability after 21 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	1.30856762150796	[107]	[160,130]	9	hSpCas9	negative selection	1021715
30451723	30451746	10	+	26627737	GBM cells	viability after 21 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.619722615818362	[197]	[181,149]	6	hSpCas9	negative selection	1021716
30458154	30458177	10	-	26627737	GBM cells	viability after 21 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	-0.015057299309067296	[319]	[170,172]	0	hSpCas9	negative selection	1021717
30459440	30459463	10	-	26627737	GBM cells	viability after 21 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.22037663114721856	[169]	[116,98]	2	hSpCas9	negative selection	1021718
30439124	30439147	10	+	26627737	RPE1	viability after 9 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.2928021012197332	[709]	[170,402]	2	hSpCas9	negative selection	1104028
30450296	30450319	10	-	26627737	RPE1	viability after 9 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	1.2979611233366177	[670]	[433,622]	7	hSpCas9	negative selection	1104029
30450365	30450388	10	+	26627737	RPE1	viability after 9 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	-0.5594421895358319	[637]	[152,112]	-4	hSpCas9	negative selection	1104030
30451723	30451746	10	+	26627737	RPE1	viability after 9 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	1.013771614567791	[449]	[142,466]	6	hSpCas9	negative selection	1104031
30458154	30458177	10	-	26627737	RPE1	viability after 9 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	-0.34752094792228383	[1647]	[463,329]	-2	hSpCas9	negative selection	1104032
30459440	30459463	10	-	26627737	RPE1	viability after 9 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	1.2169282757512883	[277]	[200,203]	7	hSpCas9	negative selection	1104033
30439124	30439147	10	+	26627737	RPE1	viability after 12 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	-0.3390711843376045	[709]	[109,193]	-2	hSpCas9	negative selection	1186343
30450296	30450319	10	-	26627737	RPE1	viability after 12 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	1.551741113356319	[670]	[494,563]	8	hSpCas9	negative selection	1186344
30450365	30450388	10	+	26627737	RPE1	viability after 12 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	-0.8044898353312355	[637]	[136,56]	-5	hSpCas9	negative selection	1186345
30451723	30451746	10	+	26627737	RPE1	viability after 12 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.651317781203166	[449]	[134,247]	4	hSpCas9	negative selection	1186346
30458154	30458177	10	-	26627737	RPE1	viability after 12 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	-0.1609284086340701	[1647]	[260,538]	-1	hSpCas9	negative selection	1186347
30459440	30459463	10	-	26627737	RPE1	viability after 12 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	1.021024357806791	[277]	[153,148]	6	hSpCas9	negative selection	1186348
30439124	30439147	10	+	26627737	RPE1	viability after 15 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.36854450274742523	[709]	[129,383]	2	hSpCas9	negative selection	1268658
30450296	30450319	10	-	26627737	RPE1	viability after 15 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	1.8905988389090538	[670]	[686,719]	8	hSpCas9	negative selection	1268659
30450365	30450388	10	+	26627737	RPE1	viability after 15 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	-0.4423459593658686	[637]	[142,122]	-3	hSpCas9	negative selection	1268660
30451723	30451746	10	+	26627737	RPE1	viability after 15 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	1.1009878338499695	[449]	[213,329]	6	hSpCas9	negative selection	1268661
30458154	30458177	10	-	26627737	RPE1	viability after 15 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.08937884880188363	[1647]	[665,331]	0	hSpCas9	negative selection	1268662
30459440	30459463	10	-	26627737	RPE1	viability after 15 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.9930351963251582	[277]	[98,211]	6	hSpCas9	negative selection	1268663
30439124	30439147	10	+	26627737	RPE1	viability after 18 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.16418098056173347	[709]	[103,332]	1	hSpCas9	negative selection	1350973
30450296	30450319	10	-	26627737	RPE1	viability after 18 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	1.9301401199888102	[670]	[546,842]	8	hSpCas9	negative selection	1350974
30450365	30450388	10	+	26627737	RPE1	viability after 18 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	-0.7372001545022318	[637]	[67,140]	-4	hSpCas9	negative selection	1350975
30451723	30451746	10	+	26627737	RPE1	viability after 18 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	1.0202070786155835	[449]	[196,298]	6	hSpCas9	negative selection	1350976
30458154	30458177	10	-	26627737	RPE1	viability after 18 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	-0.3501997146864161	[1647]	[301,398]	-2	hSpCas9	negative selection	1350977
30459440	30459463	10	-	26627737	RPE1	viability after 18 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.49600055356599726	[277]	[70,142]	3	hSpCas9	negative selection	1350978
30439124	30439147	10	+	26627737	HeLa	viability after 8 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.18672574781074677	[447]	[201,203,252]	1	hSpCas9	negative selection	1433288
30450296	30450319	10	-	26627737	HeLa	viability after 8 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	-0.35850077665611335	[328]	[125,53,154]	-3	hSpCas9	negative selection	1433289
30450365	30450388	10	+	26627737	HeLa	viability after 8 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	0.19389795055365944	[247]	[69,156,130]	1	hSpCas9	negative selection	1433290
30451723	30451746	10	+	26627737	HeLa	viability after 8 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	-0.7343795780793152	[505]	[204,104,104]	-6	hSpCas9	negative selection	1433291
30458154	30458177	10	-	26627737	HeLa	viability after 8 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.16890308532580073	[497]	[124,191,377]	1	hSpCas9	negative selection	1433292
30459440	30459463	10	-	26627737	HeLa	viability after 8 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.5798698015217181	[410]	[127,145,88]	-5	hSpCas9	negative selection	1433293
30439124	30439147	10	+	26627737	HeLa	viability after 12 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	-0.05443737576043134	[447]	[181,177,174]	0	hSpCas9	negative selection	1515603
30450296	30450319	10	-	26627737	HeLa	viability after 12 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.32597065723643726	[328]	[200,124,190]	3	hSpCas9	negative selection	1515604
30450365	30450388	10	+	26627737	HeLa	viability after 12 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	-0.011488997374328291	[247]	[55,79,169]	0	hSpCas9	negative selection	1515605
30451723	30451746	10	+	26627737	HeLa	viability after 12 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	-0.3119549549535988	[505]	[156,111,241]	-3	hSpCas9	negative selection	1515606
30458154	30458177	10	-	26627737	HeLa	viability after 12 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.937159043880099	[497]	[704,150,360]	7	hSpCas9	negative selection	1515607
30459440	30459463	10	-	26627737	HeLa	viability after 12 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.8110510765090556	[410]	[35,187,54]	-6	hSpCas9	negative selection	1515608
30439124	30439147	10	+	26627737	HeLa	viability after 15 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.04408636024846835	[447]	[222,196,139]	0	hSpCas9	negative selection	1597918
30450296	30450319	10	-	26627737	HeLa	viability after 15 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	-0.23426440004712556	[328]	[135,82,122]	-2	hSpCas9	negative selection	1597919
30450365	30450388	10	+	26627737	HeLa	viability after 15 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	-0.543974546260952	[247]	[50,14,147]	-5	hSpCas9	negative selection	1597920
30451723	30451746	10	+	26627737	HeLa	viability after 15 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	-0.7248072154537825	[505]	[158,143,65]	-6	hSpCas9	negative selection	1597921
30458154	30458177	10	-	26627737	HeLa	viability after 15 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.7169307684430257	[497]	[315,216,477]	5	hSpCas9	negative selection	1597922
30459440	30459463	10	-	26627737	HeLa	viability after 15 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-1.092084797194942	[410]	[51,114,67]	-7	hSpCas9	negative selection	1597923
30439124	30439147	10	+	26627737	HeLa	viability after 18 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	-0.024254461551237422	[447]	[135,158,139]	0	hSpCas9	negative selection	1680233
30450296	30450319	10	-	26627737	HeLa	viability after 18 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	-0.24231522982360731	[328]	[88,69,122]	-2	hSpCas9	negative selection	1680234
30450365	30450388	10	+	26627737	HeLa	viability after 18 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	-0.5033756898734363	[247]	[35,14,147]	-4	hSpCas9	negative selection	1680235
30451723	30451746	10	+	26627737	HeLa	viability after 18 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	-0.7407976911745422	[505]	[108,112,65]	-6	hSpCas9	negative selection	1680236
30458154	30458177	10	-	26627737	HeLa	viability after 18 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.7236566849817312	[497]	[209,185,477]	5	hSpCas9	negative selection	1680237
30459440	30459463	10	-	26627737	HeLa	viability after 18 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-1.0683602357877897	[410]	[39,91,67]	-7	hSpCas9	negative selection	1680238
30439124	30439147	10	+	26627737	HCT116	viability after 6 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.03836308110271512	[649]	[73,121]	0	hSpCas9	negative selection	1762548
30450296	30450319	10	-	26627737	HCT116	viability after 6 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.8935242260355394	[398]	[24,166]	5	hSpCas9	negative selection	1762549
30450365	30450388	10	+	26627737	HCT116	viability after 6 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	0.39029362660113454	[449]	[35,123]	2	hSpCas9	negative selection	1762550
30451723	30451746	10	+	26627737	HCT116	viability after 6 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	-2.250503930098859	[445]	[6,18]	-8	hSpCas9	negative selection	1762551
30458154	30458177	10	-	26627737	HCT116	viability after 6 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	1.1525863351166352	[636]	[201,233]	6	hSpCas9	negative selection	1762552
30459440	30459463	10	-	26627737	HCT116	viability after 6 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	1.419295248815625	[585]	[43,357]	7	hSpCas9	negative selection	1762553
30439124	30439147	10	+	26627737	HCT116	viability after 8 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	-0.04735542500685597	[474]	[290,254,214]	0	hSpCas9	negative selection	1844863
30450296	30450319	10	-	26627737	HCT116	viability after 8 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.3571369286264748	[246]	[131,195,193]	4	hSpCas9	negative selection	1844864
30450365	30450388	10	+	26627737	HCT116	viability after 8 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	1.691062082937235	[74]	[109,163,125]	9	hSpCas9	negative selection	1844865
30451723	30451746	10	+	26627737	HCT116	viability after 8 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.7971182916486544	[160]	[177,139,144]	7	hSpCas9	negative selection	1844866
30458154	30458177	10	-	26627737	HCT116	viability after 8 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	-0.04998376846984809	[530]	[215,289,339]	0	hSpCas9	negative selection	1844867
30459440	30459463	10	-	26627737	HCT116	viability after 8 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.34659053877114204	[189]	[144,72,180]	4	hSpCas9	negative selection	1844868
30439124	30439147	10	+	26627737	HCT116	viability after 9 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.4786975622011459	[649]	[185,285]	3	hSpCas9	negative selection	1927178
30450296	30450319	10	-	26627737	HCT116	viability after 9 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.883229589647162	[398]	[348,75]	6	hSpCas9	negative selection	1927179
30450365	30450388	10	+	26627737	HCT116	viability after 9 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	0.8723910875105039	[449]	[38,362]	6	hSpCas9	negative selection	1927180
30451723	30451746	10	+	26627737	HCT116	viability after 9 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.3572240211205869	[445]	[132,167]	2	hSpCas9	negative selection	1927181
30458154	30458177	10	-	26627737	HCT116	viability after 9 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	1.1248002940258728	[636]	[385,358]	7	hSpCas9	negative selection	1927182
30459440	30459463	10	-	26627737	HCT116	viability after 9 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	1.3303702054082576	[585]	[655,185]	8	hSpCas9	negative selection	1927183
30439124	30439147	10	+	26627737	HCT116	viability after 12 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.41681935391130953	[474]	[232,310,463]	4	hSpCas9	negative selection	2009493
30450296	30450319	10	-	26627737	HCT116	viability after 12 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.3280207593938126	[246]	[140,172,176]	3	hSpCas9	negative selection	2009494
30450365	30450388	10	+	26627737	HCT116	viability after 12 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	1.3706447043680794	[74]	[66,108,132]	9	hSpCas9	negative selection	2009495
30451723	30451746	10	+	26627737	HCT116	viability after 12 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.626218579576342	[160]	[65,193,138]	6	hSpCas9	negative selection	2009496
30458154	30458177	10	-	26627737	HCT116	viability after 12 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.41245315606998056	[530]	[430,371,305]	4	hSpCas9	negative selection	2009497
30459440	30459463	10	-	26627737	HCT116	viability after 12 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.7448464399550163	[189]	[105,151,248]	6	hSpCas9	negative selection	2009498
30439124	30439147	10	+	26627737	HCT116	viability after 15 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.19124570164941257	[474]	[475,299,179]	2	hSpCas9	negative selection	2091808
30450296	30450319	10	-	26627737	HCT116	viability after 15 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	-0.005649693385876231	[246]	[199,86,143]	0	hSpCas9	negative selection	2091809
30450365	30450388	10	+	26627737	HCT116	viability after 15 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	1.042495493138281	[74]	[111,68,87]	8	hSpCas9	negative selection	2091810
30451723	30451746	10	+	26627737	HCT116	viability after 15 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	1.0088927412817166	[160]	[124,258,166]	8	hSpCas9	negative selection	2091811
30458154	30458177	10	-	26627737	HCT116	viability after 15 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.45998388162291526	[530]	[503,370,393]	4	hSpCas9	negative selection	2091812
30459440	30459463	10	-	26627737	HCT116	viability after 15 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.9306769658383529	[189]	[136,158,317]	7	hSpCas9	negative selection	2091813
30439124	30439147	10	+	26627737	HCT116	viability after 18 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.172005283138998	[474]	[203,213,365]	1	hSpCas9	negative selection	2174123
30450296	30450319	10	-	26627737	HCT116	viability after 18 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.1607555062252013	[246]	[121,184,87]	1	hSpCas9	negative selection	2174124
30450365	30450388	10	+	26627737	HCT116	viability after 18 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	1.1919720448926634	[74]	[63,94,88]	8	hSpCas9	negative selection	2174125
30451723	30451746	10	+	26627737	HCT116	viability after 18 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.4248180701155686	[160]	[70,164,71]	3	hSpCas9	negative selection	2174126
30458154	30458177	10	-	26627737	HCT116	viability after 18 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.4221697725367589	[530]	[216,446,361]	3	hSpCas9	negative selection	2174127
30459440	30459463	10	-	26627737	HCT116	viability after 18 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.729674302870008	[189]	[136,46,285]	6	hSpCas9	negative selection	2174128
30438936	30438959	10	+	24336569	HL60	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.10597891161158945	[1097]	[2158]	-1	hSpCas9	negative selection	2275958
30439007	30439030	10	+	24336569	HL60	viability	GTCTGATGTAATAGACATTATGG	MAP3K8	ENSG00000107968	1.6781256429758937	[328]	[2227]	9	hSpCas9	negative selection	2275959
30439053	30439076	10	-	24336569	HL60	viability	AGACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	0.5179385983994413	[728]	[2208]	4	hSpCas9	negative selection	2275960
30439068	30439091	10	-	24336569	HL60	viability	TGACACATGGTCATTAGACTGGG	MAP3K8	ENSG00000107968	0.005025444578531046	[784]	[1666]	0	hSpCas9	negative selection	2275961
30439081	30439104	10	-	24336569	HL60	viability	TTGATTACTGTCTTGACACATGG	MAP3K8	ENSG00000107968	0.5686114003356573	[786]	[2469]	5	hSpCas9	negative selection	2275962
30439116	30439139	10	+	24336569	HL60	viability	TCTAAGTCTCTGCTGCTTAGTGG	MAP3K8	ENSG00000107968	-0.17956923857337004	[1079]	[2017]	-1	hSpCas9	negative selection	2275963
30439124	30439147	10	+	24336569	HL60	viability	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	1.0655875369112429	[663]	[2940]	7	hSpCas9	negative selection	2275964
30439132	30439155	10	+	24336569	HL60	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	-0.10799717107515638	[877]	[1723]	-1	hSpCas9	negative selection	2275965
30439139	30439162	10	-	24336569	HL60	viability	ATGACAACCATGGTACCTCTTGG	MAP3K8	ENSG00000107968	-0.6966248574031553	[1049]	[1370]	-6	hSpCas9	negative selection	2275966
30439149	30439172	10	-	24336569	HL60	viability	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	-0.10193757136864412	[1099]	[2168]	-1	hSpCas9	negative selection	2275967
30438936	30438959	10	+	24336569	KBM7	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.19794636961963863	[711]	[1692]	-2	hSpCas9	negative selection	2343135
30439007	30439030	10	+	24336569	KBM7	viability	GTCTGATGTAATAGACATTATGG	MAP3K8	ENSG00000107968	1.1412151657633007	[375]	[2261]	8	hSpCas9	negative selection	2343136
30439053	30439076	10	-	24336569	KBM7	viability	AGACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	0.7483410134263746	[659]	[3023]	6	hSpCas9	negative selection	2343137
30439068	30439091	10	-	24336569	KBM7	viability	TGACACATGGTCATTAGACTGGG	MAP3K8	ENSG00000107968	0.898830419773285	[595]	[3030]	7	hSpCas9	negative selection	2343138
30439081	30439104	10	-	24336569	KBM7	viability	TTGATTACTGTCTTGACACATGG	MAP3K8	ENSG00000107968	0.6735667709577455	[507]	[2209]	6	hSpCas9	negative selection	2343139
30439116	30439139	10	+	24336569	KBM7	viability	TCTAAGTCTCTGCTGCTTAGTGG	MAP3K8	ENSG00000107968	0.7030551749469582	[869]	[3862]	6	hSpCas9	negative selection	2343140
30439124	30439147	10	+	24336569	KBM7	viability	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.24162327184925048	[693]	[2237]	2	hSpCas9	negative selection	2343141
30439132	30439155	10	+	24336569	KBM7	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.9444637669803315	[750]	[3941]	7	hSpCas9	negative selection	2343142
30439139	30439162	10	-	24336569	KBM7	viability	ATGACAACCATGGTACCTCTTGG	MAP3K8	ENSG00000107968	0.24079362925380043	[784]	[2529]	2	hSpCas9	negative selection	2343143
30439149	30439172	10	-	24336569	KBM7	viability	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.5536962080200123	[847]	[3394]	5	hSpCas9	negative selection	2343144
30439053	30439076	10	-	27260157	DLD1	viability	AGACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	0.0169155941477545	[]	[]	0	hSpCas9	negative selection	2576380
30447835	30447858	10	-	27260157	DLD1	viability	TCCTGTAAGTCAGCTTCCAGGGG	MAP3K8	ENSG00000107968	0.21071622534736	[]	[]	3	hSpCas9	negative selection	2577465
30447886	30447909	10	+	27260157	DLD1	viability	CGCCTTTGGAAAGGTATACTTGG	MAP3K8	ENSG00000107968	0.463016755138885	[]	[]	8	hSpCas9	negative selection	2579086
30450308	30450331	10	-	27260157	DLD1	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-1.69705812047374	[]	[]	-8	hSpCas9	negative selection	2580750
30438936	30438959	10	+	27260157	DLD1	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.469370403571456	[]	[]	-4	hSpCas9	negative selection	2582352
30450315	30450338	10	+	27260157	DLD1	viability	GAGAACATCGCAGAGCTGTATGG	MAP3K8	ENSG00000107968	1.24012654276699	[]	[]	9	hSpCas9	negative selection	2584708
30439081	30439104	10	-	27260157	DLD1	viability	TTGATTACTGTCTTGACACATGG	MAP3K8	ENSG00000107968	0.0302136544634573	[]	[]	0	hSpCas9	negative selection	2586834
30450279	30450302	10	-	27260157	DLD1	viability	GCCTGGATTTCCACATCAGATGG	MAP3K8	ENSG00000107968	1.39114522086172	[]	[]	9	hSpCas9	negative selection	2606437
30439236	30439259	10	+	27260157	DLD1	viability	GGACAACGACCACAGGAATCTGG	MAP3K8	ENSG00000107968	0.324239557995349	[]	[]	4	hSpCas9	negative selection	2609507
30439116	30439139	10	+	27260157	DLD1	viability	TCTAAGTCTCTGCTGCTTAGTGG	MAP3K8	ENSG00000107968	-0.0545986650483541	[]	[]	0	hSpCas9	negative selection	2610383
30450296	30450319	10	-	27260157	DLD1	viability	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.431736520013244	[]	[]	7	hSpCas9	negative selection	2612759
30450278	30450301	10	+	27260157	DLD1	viability	GCCATCTGATGTGGAAATCCAGG	MAP3K8	ENSG00000107968	1.08640004792792	[]	[]	9	hSpCas9	negative selection	2613125
30439149	30439172	10	-	27260157	DLD1	viability	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.240447906063304	[]	[]	4	hSpCas9	negative selection	2613713
30439163	30439186	10	+	27260157	DLD1	viability	AGTCAGATATGGAACTGTGGAGG	MAP3K8	ENSG00000107968	-0.378877284252025	[]	[]	-3	hSpCas9	negative selection	2616059
30439124	30439147	10	+	27260157	DLD1	viability	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.555612895176055	[]	[]	8	hSpCas9	negative selection	2617238
30439068	30439091	10	-	27260157	DLD1	viability	TGACACATGGTCATTAGACTGGG	MAP3K8	ENSG00000107968	-0.524705158670895	[]	[]	-4	hSpCas9	negative selection	2618749
30439132	30439155	10	+	27260157	DLD1	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.678102614562104	[]	[]	8	hSpCas9	negative selection	2620175
30439139	30439162	10	-	27260157	DLD1	viability	ATGACAACCATGGTACCTCTTGG	MAP3K8	ENSG00000107968	-0.336170884638491	[]	[]	-3	hSpCas9	negative selection	2642846
30450289	30450312	10	+	27260157	DLD1	viability	TGGAAATCCAGGCTTGCTTCCGG	MAP3K8	ENSG00000107968	0.414273593457017	[]	[]	4	hSpCas9	negative selection	2645299
30439007	30439030	10	+	27260157	DLD1	viability	GTCTGATGTAATAGACATTATGG	MAP3K8	ENSG00000107968	1.31242437543189	[]	[]	9	hSpCas9	negative selection	2646370
30439053	30439076	10	-	27260157	HT1080	viability	AGACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	-0.238553275717194	[]	[]	0	hSpCas9	negative selection	2652510
30447835	30447858	10	-	27260157	HT1080	viability	TCCTGTAAGTCAGCTTCCAGGGG	MAP3K8	ENSG00000107968	-0.969004517219023	[]	[]	-8	hSpCas9	negative selection	2653595
30447886	30447909	10	+	27260157	HT1080	viability	CGCCTTTGGAAAGGTATACTTGG	MAP3K8	ENSG00000107968	-0.0988399720365414	[]	[]	0	hSpCas9	negative selection	2655216
30450308	30450331	10	-	27260157	HT1080	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-1.4166164874219	[]	[]	-9	hSpCas9	negative selection	2656880
30438936	30438959	10	+	27260157	HT1080	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.126428852488695	[]	[]	0	hSpCas9	negative selection	2658482
30450315	30450338	10	+	27260157	HT1080	viability	GAGAACATCGCAGAGCTGTATGG	MAP3K8	ENSG00000107968	1.13681439848639	[]	[]	8	hSpCas9	negative selection	2660838
30439081	30439104	10	-	27260157	HT1080	viability	TTGATTACTGTCTTGACACATGG	MAP3K8	ENSG00000107968	1.1098731687855	[]	[]	8	hSpCas9	negative selection	2662964
30450279	30450302	10	-	27260157	HT1080	viability	GCCTGGATTTCCACATCAGATGG	MAP3K8	ENSG00000107968	0.659759739673694	[]	[]	6	hSpCas9	negative selection	2682567
30439236	30439259	10	+	27260157	HT1080	viability	GGACAACGACCACAGGAATCTGG	MAP3K8	ENSG00000107968	1.03984820848791	[]	[]	8	hSpCas9	negative selection	2685637
30439116	30439139	10	+	27260157	HT1080	viability	TCTAAGTCTCTGCTGCTTAGTGG	MAP3K8	ENSG00000107968	0.658686311658166	[]	[]	6	hSpCas9	negative selection	2686513
30450296	30450319	10	-	27260157	HT1080	viability	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.8935169316378	[]	[]	7	hSpCas9	negative selection	2688889
30450278	30450301	10	+	27260157	HT1080	viability	GCCATCTGATGTGGAAATCCAGG	MAP3K8	ENSG00000107968	0.225174084139916	[]	[]	2	hSpCas9	negative selection	2689255
30439149	30439172	10	-	27260157	HT1080	viability	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	1.13269780510731	[]	[]	8	hSpCas9	negative selection	2689843
30439163	30439186	10	+	27260157	HT1080	viability	AGTCAGATATGGAACTGTGGAGG	MAP3K8	ENSG00000107968	-0.0461207977207332	[]	[]	0	hSpCas9	negative selection	2692189
30439124	30439147	10	+	27260157	HT1080	viability	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.833016829606439	[]	[]	7	hSpCas9	negative selection	2693368
30439068	30439091	10	-	27260157	HT1080	viability	TGACACATGGTCATTAGACTGGG	MAP3K8	ENSG00000107968	0.530003433790769	[]	[]	5	hSpCas9	negative selection	2694879
30439132	30439155	10	+	27260157	HT1080	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	1.01083216383084	[]	[]	8	hSpCas9	negative selection	2696305
30439139	30439162	10	-	27260157	HT1080	viability	ATGACAACCATGGTACCTCTTGG	MAP3K8	ENSG00000107968	0.620410998310888	[]	[]	5	hSpCas9	negative selection	2718976
30450289	30450312	10	+	27260157	HT1080	viability	TGGAAATCCAGGCTTGCTTCCGG	MAP3K8	ENSG00000107968	0.136497313629301	[]	[]	1	hSpCas9	negative selection	2721429
30439007	30439030	10	+	27260157	HT1080	viability	GTCTGATGTAATAGACATTATGG	MAP3K8	ENSG00000107968	-0.0235608023273475	[]	[]	0	hSpCas9	negative selection	2722500
30439053	30439076	10	-	27260157	MKN45	viability	AGACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	0.943611016519624	[]	[]	8	hSpCas9	negative selection	2728640
30447835	30447858	10	-	27260157	MKN45	viability	TCCTGTAAGTCAGCTTCCAGGGG	MAP3K8	ENSG00000107968	-0.0730367502788192	[]	[]	0	hSpCas9	negative selection	2729725
30447886	30447909	10	+	27260157	MKN45	viability	CGCCTTTGGAAAGGTATACTTGG	MAP3K8	ENSG00000107968	-0.350645128314449	[]	[]	-1	hSpCas9	negative selection	2731346
30450308	30450331	10	-	27260157	MKN45	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-1.04074311931009	[]	[]	-8	hSpCas9	negative selection	2733010
30438936	30438959	10	+	27260157	MKN45	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.917519104986439	[]	[]	-7	hSpCas9	negative selection	2734612
30450315	30450338	10	+	27260157	MKN45	viability	GAGAACATCGCAGAGCTGTATGG	MAP3K8	ENSG00000107968	1.41119123715646	[]	[]	9	hSpCas9	negative selection	2736968
30439081	30439104	10	-	27260157	MKN45	viability	TTGATTACTGTCTTGACACATGG	MAP3K8	ENSG00000107968	0.393596936829023	[]	[]	6	hSpCas9	negative selection	2739094
30450279	30450302	10	-	27260157	MKN45	viability	GCCTGGATTTCCACATCAGATGG	MAP3K8	ENSG00000107968	0.65987108560916	[]	[]	7	hSpCas9	negative selection	2758697
30439236	30439259	10	+	27260157	MKN45	viability	GGACAACGACCACAGGAATCTGG	MAP3K8	ENSG00000107968	1.4811803012878	[]	[]	9	hSpCas9	negative selection	2761767
30439116	30439139	10	+	27260157	MKN45	viability	TCTAAGTCTCTGCTGCTTAGTGG	MAP3K8	ENSG00000107968	-0.419110966383762	[]	[]	-6	hSpCas9	negative selection	2762643
30450296	30450319	10	-	27260157	MKN45	viability	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	1.43447480427986	[]	[]	9	hSpCas9	negative selection	2765019
30450278	30450301	10	+	27260157	MKN45	viability	GCCATCTGATGTGGAAATCCAGG	MAP3K8	ENSG00000107968	-0.286696820453301	[]	[]	-1	hSpCas9	negative selection	2765385
30439149	30439172	10	-	27260157	MKN45	viability	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.591335353092767	[]	[]	7	hSpCas9	negative selection	2765973
30439163	30439186	10	+	27260157	MKN45	viability	AGTCAGATATGGAACTGTGGAGG	MAP3K8	ENSG00000107968	0.618822231106852	[]	[]	7	hSpCas9	negative selection	2768319
30439124	30439147	10	+	27260157	MKN45	viability	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.743687733128374	[]	[]	7	hSpCas9	negative selection	2769498
30439068	30439091	10	-	27260157	MKN45	viability	TGACACATGGTCATTAGACTGGG	MAP3K8	ENSG00000107968	0.536499209284894	[]	[]	6	hSpCas9	negative selection	2771009
30439132	30439155	10	+	27260157	MKN45	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.852129275242649	[]	[]	8	hSpCas9	negative selection	2772435
30439139	30439162	10	-	27260157	MKN45	viability	ATGACAACCATGGTACCTCTTGG	MAP3K8	ENSG00000107968	0.0736210962010551	[]	[]	0	hSpCas9	negative selection	2795106
30450289	30450312	10	+	27260157	MKN45	viability	TGGAAATCCAGGCTTGCTTCCGG	MAP3K8	ENSG00000107968	0.524540278001658	[]	[]	6	hSpCas9	negative selection	2797559
30439007	30439030	10	+	27260157	MKN45	viability	GTCTGATGTAATAGACATTATGG	MAP3K8	ENSG00000107968	0.292822074417274	[]	[]	5	hSpCas9	negative selection	2798630
30439053	30439076	10	-	27260157	RKO	viability	AGACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	-0.378291699002879	[]	[]	-6	hSpCas9	negative selection	2804770
30447835	30447858	10	-	27260157	RKO	viability	TCCTGTAAGTCAGCTTCCAGGGG	MAP3K8	ENSG00000107968	-0.81517759329584	[]	[]	-7	hSpCas9	negative selection	2805855
30447886	30447909	10	+	27260157	RKO	viability	CGCCTTTGGAAAGGTATACTTGG	MAP3K8	ENSG00000107968	-0.129407534090236	[]	[]	0	hSpCas9	negative selection	2807476
30450308	30450331	10	-	27260157	RKO	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-1.01966078285814	[]	[]	-8	hSpCas9	negative selection	2809140
30438936	30438959	10	+	27260157	RKO	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.11511124024148	[]	[]	0	hSpCas9	negative selection	2810742
30450315	30450338	10	+	27260157	RKO	viability	GAGAACATCGCAGAGCTGTATGG	MAP3K8	ENSG00000107968	0.709273893886954	[]	[]	8	hSpCas9	negative selection	2813098
30439081	30439104	10	-	27260157	RKO	viability	TTGATTACTGTCTTGACACATGG	MAP3K8	ENSG00000107968	0.0670299143179181	[]	[]	0	hSpCas9	negative selection	2815224
30450279	30450302	10	-	27260157	RKO	viability	GCCTGGATTTCCACATCAGATGG	MAP3K8	ENSG00000107968	0.241876195394685	[]	[]	1	hSpCas9	negative selection	2834827
30439236	30439259	10	+	27260157	RKO	viability	GGACAACGACCACAGGAATCTGG	MAP3K8	ENSG00000107968	0.485194740954298	[]	[]	2	hSpCas9	negative selection	2837897
30439116	30439139	10	+	27260157	RKO	viability	TCTAAGTCTCTGCTGCTTAGTGG	MAP3K8	ENSG00000107968	-0.907648356263574	[]	[]	-8	hSpCas9	negative selection	2838773
30450296	30450319	10	-	27260157	RKO	viability	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.956447819106001	[]	[]	8	hSpCas9	negative selection	2841149
30450278	30450301	10	+	27260157	RKO	viability	GCCATCTGATGTGGAAATCCAGG	MAP3K8	ENSG00000107968	-0.087756129092043	[]	[]	0	hSpCas9	negative selection	2841515
30439149	30439172	10	-	27260157	RKO	viability	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	1.0005687576764	[]	[]	9	hSpCas9	negative selection	2842103
30439163	30439186	10	+	27260157	RKO	viability	AGTCAGATATGGAACTGTGGAGG	MAP3K8	ENSG00000107968	-0.0821564771437955	[]	[]	0	hSpCas9	negative selection	2844449
30439124	30439147	10	+	27260157	RKO	viability	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	-0.140988623826531	[]	[]	0	hSpCas9	negative selection	2845628
30439068	30439091	10	-	27260157	RKO	viability	TGACACATGGTCATTAGACTGGG	MAP3K8	ENSG00000107968	0.305431716965849	[]	[]	1	hSpCas9	negative selection	2847139
30439132	30439155	10	+	27260157	RKO	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.573963860228616	[]	[]	3	hSpCas9	negative selection	2848565
30439139	30439162	10	-	27260157	RKO	viability	ATGACAACCATGGTACCTCTTGG	MAP3K8	ENSG00000107968	0.0820385478593944	[]	[]	0	hSpCas9	negative selection	2871236
30450289	30450312	10	+	27260157	RKO	viability	TGGAAATCCAGGCTTGCTTCCGG	MAP3K8	ENSG00000107968	-0.51945990643865	[]	[]	-6	hSpCas9	negative selection	2873689
30439007	30439030	10	+	27260157	RKO	viability	GTCTGATGTAATAGACATTATGG	MAP3K8	ENSG00000107968	0.654651768333874	[]	[]	3	hSpCas9	negative selection	2874760
30439053	30439076	10	-	27260157	SF268	viability	AGACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	0.390901636459746	[]	[]	4	hSpCas9	negative selection	2880900
30447835	30447858	10	-	27260157	SF268	viability	TCCTGTAAGTCAGCTTCCAGGGG	MAP3K8	ENSG00000107968	-0.613806258763235	[]	[]	-5	hSpCas9	negative selection	2881985
30447886	30447909	10	+	27260157	SF268	viability	CGCCTTTGGAAAGGTATACTTGG	MAP3K8	ENSG00000107968	-0.318772664629292	[]	[]	-2	hSpCas9	negative selection	2883606
30450308	30450331	10	-	27260157	SF268	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.512219554961159	[]	[]	-4	hSpCas9	negative selection	2885270
30438936	30438959	10	+	27260157	SF268	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.73691452714871	[]	[]	-5	hSpCas9	negative selection	2886872
30450315	30450338	10	+	27260157	SF268	viability	GAGAACATCGCAGAGCTGTATGG	MAP3K8	ENSG00000107968	1.01676706667494	[]	[]	9	hSpCas9	negative selection	2889228
30439081	30439104	10	-	27260157	SF268	viability	TTGATTACTGTCTTGACACATGG	MAP3K8	ENSG00000107968	0.160519930766243	[]	[]	0	hSpCas9	negative selection	2891354
30450279	30450302	10	-	27260157	SF268	viability	GCCTGGATTTCCACATCAGATGG	MAP3K8	ENSG00000107968	1.11401752177317	[]	[]	9	hSpCas9	negative selection	2910957
30439236	30439259	10	+	27260157	SF268	viability	GGACAACGACCACAGGAATCTGG	MAP3K8	ENSG00000107968	0.906407631616025	[]	[]	9	hSpCas9	negative selection	2914027
30439116	30439139	10	+	27260157	SF268	viability	TCTAAGTCTCTGCTGCTTAGTGG	MAP3K8	ENSG00000107968	-0.109332374828752	[]	[]	-1	hSpCas9	negative selection	2914903
30450296	30450319	10	-	27260157	SF268	viability	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.971911216638738	[]	[]	9	hSpCas9	negative selection	2917279
30450278	30450301	10	+	27260157	SF268	viability	GCCATCTGATGTGGAAATCCAGG	MAP3K8	ENSG00000107968	0.780947303133941	[]	[]	8	hSpCas9	negative selection	2917645
30439149	30439172	10	-	27260157	SF268	viability	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.417387756416646	[]	[]	4	hSpCas9	negative selection	2918233
30439163	30439186	10	+	27260157	SF268	viability	AGTCAGATATGGAACTGTGGAGG	MAP3K8	ENSG00000107968	0.494901165180758	[]	[]	7	hSpCas9	negative selection	2920579
30439124	30439147	10	+	27260157	SF268	viability	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	-1.25808200697097	[]	[]	-7	hSpCas9	negative selection	2921758
30439068	30439091	10	-	27260157	SF268	viability	TGACACATGGTCATTAGACTGGG	MAP3K8	ENSG00000107968	0.240833480635494	[]	[]	3	hSpCas9	negative selection	2923269
30439132	30439155	10	+	27260157	SF268	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.99747886469799	[]	[]	9	hSpCas9	negative selection	2924695
30439139	30439162	10	-	27260157	SF268	viability	ATGACAACCATGGTACCTCTTGG	MAP3K8	ENSG00000107968	1.0480909878601	[]	[]	9	hSpCas9	negative selection	2947366
30450289	30450312	10	+	27260157	SF268	viability	TGGAAATCCAGGCTTGCTTCCGG	MAP3K8	ENSG00000107968	0.697667979733345	[]	[]	8	hSpCas9	negative selection	2949819
30439007	30439030	10	+	27260157	SF268	viability	GTCTGATGTAATAGACATTATGG	MAP3K8	ENSG00000107968	-0.029669824956839	[]	[]	0	hSpCas9	negative selection	2950890
30438920	30438943	10	+	27013184	SW480	treatment with recombinant TRAIL	TCCAGAAAGAGCAACAGTAATGG	MAP3K8	ENSG00000107968	-1.1486311155604707	[214,353]	[28,89]	-5	hSpCas9	positive selection	2957377
30447886	30447909	10	+	27013184	SW480	treatment with recombinant TRAIL	CGCCTTTGGAAAGGTATACTTGG	MAP3K8	ENSG00000107968	0.833429828917822	[84,60]	[51,63]	4	hSpCas9	positive selection	2957378
30447779	30447802	10	+	27013184	SW480	treatment with recombinant TRAIL	TAGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	1.3692673270522095	[295,234]	[298,298]	6	hSpCas9	positive selection	2957379
30438936	30438959	10	+	27013184	SW480	treatment with recombinant TRAIL	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	2.395337474716118	[25,39]	[30,133]	8	hSpCas9	positive selection	2957380
30447834	30447857	10	+	27013184	SW480	treatment with recombinant TRAIL	TCCCCTGGAAGCTGACTTACAGG	MAP3K8	ENSG00000107968	0.7029513464989672	[443,418]	[326,270]	3	hSpCas9	positive selection	2957381
30439053	30439076	10	-	27013184	SW480	treatment with recombinant TRAIL	AGACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	-0.23746989049244993	[1048,1328]	[213,738]	-1	hSpCas9	positive selection	2957382
30447837	30447860	10	-	27013184	SW480	treatment with recombinant TRAIL	ATTCCTGTAAGTCAGCTTCCAGG	MAP3K8	ENSG00000107968	1.096571925820319	[314,480]	[253,511]	5	hSpCas9	positive selection	2957383
30439068	30439091	10	-	27013184	SW480	treatment with recombinant TRAIL	TGACACATGGTCATTAGACTGGG	MAP3K8	ENSG00000107968	-4.711450641142655	[94,152]	[1,1]	-9	hSpCas9	positive selection	2957384
30439069	30439092	10	-	27013184	SW480	treatment with recombinant TRAIL	TTGACACATGGTCATTAGACTGG	MAP3K8	ENSG00000107968	1.6212430339454613	[40,144]	[177,30]	7	hSpCas9	positive selection	2957385
30439081	30439104	10	-	27013184	SW480	treatment with recombinant TRAIL	TTGATTACTGTCTTGACACATGG	MAP3K8	ENSG00000107968	-1.8881397694628728	[205,78]	[27,1]	-7	hSpCas9	positive selection	2957386
30439139	30439162	10	-	27013184	SW480	treatment with recombinant TRAIL	ATGACAACCATGGTACCTCTTGG	MAP3K8	ENSG00000107968	-1.1213228074840136	[512,456]	[99,91]	-5	hSpCas9	positive selection	2957387
30439149	30439172	10	-	27013184	SW480	treatment with recombinant TRAIL	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.09437639865716929	[386,532]	[132,316]	0	hSpCas9	positive selection	2957388
30439245	30439268	10	-	27013184	SW480	treatment with recombinant TRAIL	AATAAAATTCCAGATTCCTGTGG	MAP3K8	ENSG00000107968	0.6708524443886077	[1,3]	[1,1]	3	hSpCas9	positive selection	2957389
30447888	30447911	10	-	27013184	SW480	treatment with recombinant TRAIL	TGCCAAGTATACCTTTCCAAAGG	MAP3K8	ENSG00000107968	0.35353986657799796	[355,297]	[47,371]	1	hSpCas9	positive selection	2957390
30439116	30439139	10	+	27013184	SW480	treatment with recombinant TRAIL	TCTAAGTCTCTGCTGCTTAGTGG	MAP3K8	ENSG00000107968	-1.9722650652481044	[301,158]	[30,18]	-7	hSpCas9	positive selection	2957391
30447842	30447865	10	+	27013184	SW480	treatment with recombinant TRAIL	AAGCTGACTTACAGGAATATTGG	MAP3K8	ENSG00000107968	3.4330113117777272	[35,1]	[69,131]	9	hSpCas9	positive selection	2957392
30450261	30450284	10	-	27013184	SW480	treatment with recombinant TRAIL	GATGGCTTAAATTGATCTACTGG	MAP3K8	ENSG00000107968	2.0490328736992893	[340,367]	[561,728]	8	hSpCas9	positive selection	2957393
30450344	30450367	10	-	27013184	SW480	treatment with recombinant TRAIL	GATGGACAGTTTCACCCCACAGG	MAP3K8	ENSG00000107968	1.202884238927355	[460,453]	[448,462]	5	hSpCas9	positive selection	2957394
30439124	30439147	10	+	27013184	SW480	treatment with recombinant TRAIL	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	1.8005681640762918	[1498,1691]	[2184,2670]	7	hSpCas9	positive selection	2957395
30447791	30447814	10	-	27013184	SW480	treatment with recombinant TRAIL	ATTTGGTAACGTCCATTTTGGGG	MAP3K8	ENSG00000107968	0.7516437334535842	[213,348]	[252,124]	3	hSpCas9	positive selection	2957396
30439132	30439155	10	+	27013184	SW480	treatment with recombinant TRAIL	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.5776864836594342	[91,79]	[44,70]	3	hSpCas9	positive selection	2957397
30447792	30447815	10	-	27013184	SW480	treatment with recombinant TRAIL	TATTTGGTAACGTCCATTTTGGG	MAP3K8	ENSG00000107968	-1.2853875172503106	[315,358]	[32,96]	-5	hSpCas9	positive selection	2957398
30439152	30439175	10	+	27013184	SW480	treatment with recombinant TRAIL	TGGTTGTCATCAGTCAGATATGG	MAP3K8	ENSG00000107968	-0.7049787253754409	[345,468]	[46,190]	-3	hSpCas9	positive selection	2957399
30447793	30447816	10	-	27013184	SW480	treatment with recombinant TRAIL	CTATTTGGTAACGTCCATTTTGG	MAP3K8	ENSG00000107968	2.7255350626463377	[46,87]	[217,143]	9	hSpCas9	positive selection	2957400
30439160	30439183	10	+	27013184	SW480	treatment with recombinant TRAIL	ATCAGTCAGATATGGAACTGTGG	MAP3K8	ENSG00000107968	0.4940981505141244	[355,242]	[227,123]	2	hSpCas9	positive selection	2957401
30447808	30447831	10	-	27013184	SW480	treatment with recombinant TRAIL	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.7035428369577481	[134,135]	[62,140]	3	hSpCas9	positive selection	2957402
30450360	30450383	10	+	27013184	SW480	treatment with recombinant TRAIL	GTCCATCTCTTTATGGAAGCAGG	MAP3K8	ENSG00000107968	1.4686761528113528	[539,631]	[694,694]	6	hSpCas9	positive selection	2957403
30447829	30447852	10	-	27013184	SW480	treatment with recombinant TRAIL	AAGTCAGCTTCCAGGGGATCAGG	MAP3K8	ENSG00000107968	-1.378438881350646	[414,938]	[91,131]	-6	hSpCas9	positive selection	2957404
30447835	30447858	10	-	27013184	SW480	treatment with recombinant TRAIL	TCCTGTAAGTCAGCTTCCAGGGG	MAP3K8	ENSG00000107968	2.537523935895501	[153,113]	[314,375]	9	hSpCas9	positive selection	2957405
30447836	30447859	10	-	27013184	SW480	treatment with recombinant TRAIL	TTCCTGTAAGTCAGCTTCCAGGG	MAP3K8	ENSG00000107968	2.149880993703805	[228,225]	[463,395]	8	hSpCas9	positive selection	2957406
30438937	30438960	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.13395027910640586	[4,4]	[5,2]	3	hSpCas9	positive selection	3001178
30439149	30439172	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	-0.1206355698772908	[3,3]	[3,1]	-2	hSpCas9	positive selection	3001179
30439133	30439156	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.4470085966152339	[3,3]	[5,3]	8	hSpCas9	positive selection	3001180
30450371	30450394	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATGGAAGCAGGCGAGGGAGGG	MAP3K8	ENSG00000107968	0.38937547706032993	[3,3]	[4,4]	7	hSpCas9	positive selection	3001181
30438937	30438960	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.052372268452322485	[4,4]	[3,2]	0	hSpCas9	positive selection	3069036
30439149	30439172	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	-0.5452704598384828	[3,3]	[2,0]	-7	hSpCas9	positive selection	3069037
30439133	30439156	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	-0.19568983105863824	[3,3]	[2,1]	-3	hSpCas9	positive selection	3069038
30450371	30450394	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATGGAAGCAGGCGAGGGAGGG	MAP3K8	ENSG00000107968	0.048909656064000245	[3,3]	[4,1]	0	hSpCas9	positive selection	3069039
30447808	30447831		-	24336571	A375	resistance to PLX after 7 days	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.08842012164085422	[5,3]	[4,5]	3	hSpCas9	positive selection	3126308
30450269	30450292		+	24336571	A375	resistance to PLX after 7 days	TCAATTTAAGCCATCTGATGTGG	MAP3K8	ENSG00000107968	-0.11699711827279138	[14,13]	[11,13]	-4	hSpCas9	positive selection	3126310
30450353	30450376		+	24336571	A375	resistance to PLX after 7 days	TGAAACTGTCCATCTCTTTATGG	MAP3K8	ENSG00000107968	0.11123082585886124	[20,18]	[19,23]	4	hSpCas9	positive selection	3126311
30447872	30447895		+	24336571	A375	resistance to PLX after 7 days	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	-0.08021204862252879	[9,9]	[9,7]	-2	hSpCas9	positive selection	3126312
30447808	30447831		-	24336571	A375	resistance to PLX after 14 days	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.9079646625838609	[6,1]	[3,3]	7	hSpCas9	positive selection	3184101
30450269	30450292		+	24336571	A375	resistance to PLX after 14 days	TCAATTTAAGCCATCTGATGTGG	MAP3K8	ENSG00000107968	-0.0695036498892965	[19,11]	[6,5]	0	hSpCas9	positive selection	3184103
30450353	30450376		+	24336571	A375	resistance to PLX after 14 days	TGAAACTGTCCATCTCTTTATGG	MAP3K8	ENSG00000107968	-0.7951607388412117	[20,19]	[4,4]	-8	hSpCas9	positive selection	3184104
30447872	30447895		+	24336571	A375	resistance to PLX after 14 days	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.12136161906113581	[8,12]	[5,4]	1	hSpCas9	positive selection	3184105
30447808	30447831		-	24336571	A375	viability after 7 days	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	-0.5811333056905903	[8]	[5,3]	-7	hSpCas9	negative selection	3241894
30450269	30450292		+	24336571	A375	viability after 7 days	TCAATTTAAGCCATCTGATGTGG	MAP3K8	ENSG00000107968	0.3449252953212557	[11]	[14,13]	5	hSpCas9	negative selection	3241896
30450353	30450376		+	24336571	A375	viability after 7 days	TGAAACTGTCCATCTCTTTATGG	MAP3K8	ENSG00000107968	0.25385320056238425	[17]	[20,18]	4	hSpCas9	negative selection	3241897
30447872	30447895		+	24336571	A375	viability after 7 days	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.1248484784913978	[8]	[9,9]	2	hSpCas9	negative selection	3241898
30447808	30447831		-	24336571	A375	viability after 14 days	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	-0.7526573974159292	[8]	[6,1]	-7	hSpCas9	negative selection	3299687
30450269	30450292		+	24336571	A375	viability after 14 days	TCAATTTAAGCCATCTGATGTGG	MAP3K8	ENSG00000107968	0.5316055000950992	[11]	[19,11]	6	hSpCas9	negative selection	3299689
30450353	30450376		+	24336571	A375	viability after 14 days	TGAAACTGTCCATCTCTTTATGG	MAP3K8	ENSG00000107968	0.27928133421296764	[17]	[20,19]	3	hSpCas9	negative selection	3299690
30447872	30447895		+	24336571	A375	viability after 14 days	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.29415471284550004	[8]	[8,12]	4	hSpCas9	negative selection	3299691
30447872	30447895	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.08740121000352279	[143,143]	[0,0]	0	hSpCas9	positive selection	3378432
30458223	30458246	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.08252379143878971	[161,161]	[0,0]	0	hSpCas9	positive selection	3378433
30450503	30450526	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	0.4244361972810935	[113,113]	[0,0]	2	hSpCas9	positive selection	3378434
30438936	30438959	10	+	26780180	HT29	viability (Avana library 4 designs)	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.164214356431467	[]	[]	0	hSpCas9	negative selection	3438822
30439149	30439172	10	-	26780180	HT29	viability (Avana library 4 designs)	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	-0.417564322871993	[]	[]	-6	hSpCas9	negative selection	3438823
30439132	30439155	10	+	26780180	HT29	viability (Avana library 4 designs)	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.790610133409987	[]	[]	3	hSpCas9	negative selection	3438824
30450370	30450393	10	+	26780180	HT29	viability (Avana library 4 designs)	TTATGGAAGCAGGCGAGGGAGGG	MAP3K8	ENSG00000107968	0.75479056590775	[]	[]	3	hSpCas9	negative selection	3438825
30439132	30439155	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	3.73324547185133	[]	[]	6	hSpCas9	negative selection	3528263
30439149	30439172	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	-0.888523806839168	[]	[]	-1	hSpCas9	negative selection	3528264
30438936	30438959	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	2.75315013977938	[]	[]	4	hSpCas9	negative selection	3528265
30450370	30450393	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATGGAAGCAGGCGAGGGAGGG	MAP3K8	ENSG00000107968	4.51890841987645	[]	[]	7	hSpCas9	negative selection	3528266
30447819	30447842	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGGGGATCAGGAGAACATCGG	MAP3K8	ENSG00000107968	3.10667793603704	[]	[]	5	hSpCas9	negative selection	3528267
30447878	30447901	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTTTCCAAAGGCGCCCCGAGG	MAP3K8	ENSG00000107968	7.26517049902996	[]	[]	9	hSpCas9	negative selection	3528268
30439132	30439155	10	+	26780180	A375	viability (Avana lentiGuide)	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	-0.0759060664312223	[]	[]	0	hSpCas9	negative selection	3636922
30439149	30439172	10	-	26780180	A375	viability (Avana lentiGuide)	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	-5.5343799951555	[]	[]	-8	hSpCas9	negative selection	3636923
30438936	30438959	10	+	26780180	A375	viability (Avana lentiGuide)	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.975011637851487	[]	[]	1	hSpCas9	negative selection	3636924
30450370	30450393	10	+	26780180	A375	viability (Avana lentiGuide)	TTATGGAAGCAGGCGAGGGAGGG	MAP3K8	ENSG00000107968	0.168460707963065	[]	[]	0	hSpCas9	negative selection	3636925
30447819	30447842	10	-	26780180	A375	viability (Avana lentiGuide)	CCAGGGGATCAGGAGAACATCGG	MAP3K8	ENSG00000107968	-2.18971582204091	[]	[]	-4	hSpCas9	negative selection	3636926
30447878	30447901	10	-	26780180	A375	viability (Avana lentiGuide)	ACCTTTCCAAAGGCGCCCCGAGG	MAP3K8	ENSG00000107968	-1.17976422596459	[]	[]	-2	hSpCas9	negative selection	3636927
30439132	30439155	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.2546525904094329	[5]	[6,5]	7	hSpCas9	positive selection	3745581
30439149	30439172	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	-0.2536340472192316	[5]	[5,3]	-4	hSpCas9	positive selection	3745582
30438936	30438959	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.03153498033824603	[5]	[5,4]	0	hSpCas9	positive selection	3745583
30450370	30450393	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATGGAAGCAGGCGAGGGAGGG	MAP3K8	ENSG00000107968	0.26027374387672475	[5]	[6,6]	7	hSpCas9	positive selection	3745584
30447819	30447842	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGGGGATCAGGAGAACATCGG	MAP3K8	ENSG00000107968	0.3853277371515851	[4]	[5,6]	9	hSpCas9	positive selection	3745585
30447878	30447901	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTTTCCAAAGGCGCCCCGAGG	MAP3K8	ENSG00000107968	0.38897620753436707	[5]	[7,7]	9	hSpCas9	positive selection	3745586
30439132	30439155	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	-0.025736079435050442	[5]	[4,4]	0	hSpCas9	positive selection	3854188
30439149	30439172	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.048447717268792385	[5]	[5,3]	1	hSpCas9	positive selection	3854189
30438936	30438959	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.5772273398345468	[5]	[1,4]	-6	hSpCas9	positive selection	3854190
30450370	30450393	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATGGAAGCAGGCGAGGGAGGG	MAP3K8	ENSG00000107968	0.28324147581675335	[5]	[5,6]	7	hSpCas9	positive selection	3854191
30447819	30447842	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGGGGATCAGGAGAACATCGG	MAP3K8	ENSG00000107968	0.25296503212957533	[5]	[5,5]	6	hSpCas9	positive selection	3854192
30447878	30447901	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTTTCCAAAGGCGCCCCGAGG	MAP3K8	ENSG00000107968	0.19778751441795334	[6]	[5,6]	5	hSpCas9	positive selection	3854193
30450503	30450526	10	-	26780180	A375	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	0.881450273555763	[]	[]	3	hSpCas9	negative selection	3959709
30458223	30458246	10	-	26780180	A375	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	1.20290313347991	[]	[]	6	hSpCas9	negative selection	3959710
30458187	30458210	10	-	26780180	A375	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	1.54081538576767	[]	[]	8	hSpCas9	negative selection	3959711
30450308	30450331	10	-	26780180	A375	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	1.25310558858552	[]	[]	6	hSpCas9	negative selection	3959712
30447808	30447831	10	-	26780180	A375	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.673549055982939	[]	[]	2	hSpCas9	negative selection	3959713
30447872	30447895	10	+	26780180	A375	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.400811649215603	[]	[]	1	hSpCas9	negative selection	3959714
30450503	30450526	10	-	26780180	HT29	viability (GeCKOv2 library)	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	0.969326298404131	[]	[]	4	hSpCas9	negative selection	4067675
30458223	30458246	10	-	26780180	HT29	viability (GeCKOv2 library)	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	1.51420670124977	[]	[]	7	hSpCas9	negative selection	4067676
30458187	30458210	10	-	26780180	HT29	viability (GeCKOv2 library)	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	1.73140493404701	[]	[]	8	hSpCas9	negative selection	4067677
30450308	30450331	10	-	26780180	HT29	viability (GeCKOv2 library)	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	2.22051342164106	[]	[]	9	hSpCas9	negative selection	4067678
30447808	30447831	10	-	26780180	HT29	viability (GeCKOv2 library)	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.519086311295716	[]	[]	1	hSpCas9	negative selection	4067679
30447872	30447895	10	+	26780180	HT29	viability (GeCKOv2 library)	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.465046545308655	[]	[]	1	hSpCas9	negative selection	4067680
30447808	30447831	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.13699114408801455	[2]	[1,1]	3	hSpCas9	positive selection	4150525
30450269	30450292	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAATTTAAGCCATCTGATGTGG	MAP3K8	ENSG00000107968	-0.04973359582598306	[3]	[2,2]	-1	hSpCas9	positive selection	4150527
30450353	30450376	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAAACTGTCCATCTCTTTATGG	MAP3K8	ENSG00000107968	-0.2145674829720019	[4]	[2,2]	-5	hSpCas9	positive selection	4150528
30447872	30447895	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	-0.42202026521483205	[3]	[0,2]	-8	hSpCas9	positive selection	4150529
30447808	30447831	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	-0.25722557930049783	[2]	[0,0,1,0]	-4	hSpCas9	positive selection	4214547
30450269	30450292	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAATTTAAGCCATCTGATGTGG	MAP3K8	ENSG00000107968	0.657021289888128	[3]	[1,0,1,3]	4	hSpCas9	positive selection	4214549
30450353	30450376	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAAACTGTCCATCTCTTTATGG	MAP3K8	ENSG00000107968	0.44165666661638125	[3]	[4,4,1,0]	3	hSpCas9	positive selection	4214550
30447872	30447895	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.5810988324448082	[2]	[2,3,2,0]	4	hSpCas9	positive selection	4214551
30447808	30447831	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.3038793988881121	[1]	[1,0]	6	hSpCas9	positive selection	4281861
30458187	30458210	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	-0.25341586628632434	[2]	[1,1]	-5	hSpCas9	positive selection	4281862
30450308	30450331	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.23524120960898626	[3]	[1,1]	-5	hSpCas9	positive selection	4281863
30447872	30447895	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.31738226486648563	[3]	[4,3]	6	hSpCas9	positive selection	4346119
30458223	30458246	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.462672917472936	[3]	[2,0]	-7	hSpCas9	positive selection	4346120
30450503	30450526	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.2486006472260351	[2]	[1,1]	-5	hSpCas9	positive selection	4346121
30439053	30439075	10	-	27760321	OCIAML3	viability	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	-0.31421801002653044	[596,485]	[337,339]	-3	hSpCas9	negative selection	4416639
30439149	30439171	10	-	27760321	OCIAML3	viability	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.10804844869524688	[337,280]	[165,381]	1	hSpCas9	negative selection	4416640
30447780	30447802	10	+	27760321	OCIAML3	viability	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	0.9879729604645854	[294,258]	[410,451]	9	hSpCas9	negative selection	4416641
30447820	30447842	10	+	27760321	OCIAML3	viability	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	0.3334180952630643	[1198,1068]	[1124,1103]	4	hSpCas9	negative selection	4416642
30450308	30450330	10	-	27760321	OCIAML3	viability	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.10330048284142923	[648,557]	[362,535]	-1	hSpCas9	negative selection	4416643
30439053	30439075	10	-	27760321	OCIAML2	viability	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	0.19599987331435154	[596,485]	[424,596]	2	hSpCas9	negative selection	4500102
30439149	30439171	10	-	27760321	OCIAML2	viability	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.8468767234905725	[337,280]	[431,469]	9	hSpCas9	negative selection	4500103
30447780	30447802	10	+	27760321	OCIAML2	viability	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	0.26528885614068193	[294,258]	[260,278]	3	hSpCas9	negative selection	4500104
30447820	30447842	10	+	27760321	OCIAML2	viability	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	0.29085007357346826	[1198,1068]	[1001,1276]	4	hSpCas9	negative selection	4500105
30450308	30450330	10	-	27760321	OCIAML2	viability	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.039726862864908064	[648,557]	[423,600]	0	hSpCas9	negative selection	4500106
30439053	30439075	10	-	27760321	MV411	viability	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	0.05096639956701898	[596,485]	[231,572]	0	hSpCas9	negative selection	4583565
30439149	30439171	10	-	27760321	MV411	viability	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	1.6272251632564516	[337,280]	[911,201]	9	hSpCas9	negative selection	4583566
30447780	30447802	10	+	27760321	MV411	viability	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	0.030305274315637898	[294,258]	[53,384]	0	hSpCas9	negative selection	4583567
30447820	30447842	10	+	27760321	MV411	viability	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	0.3940266248836577	[1198,1068]	[917,1077]	3	hSpCas9	negative selection	4583568
30450308	30450330	10	-	27760321	MV411	viability	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.12641841491539124	[648,557]	[263,687]	0	hSpCas9	negative selection	4583569
30439053	30439075	10	-	27760321	HL60	viability	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	-0.338663878982848	[596,485]	[380,312]	-4	hSpCas9	negative selection	4667028
30439149	30439171	10	-	27760321	HL60	viability	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	-0.4201906768318273	[337,280]	[175,200]	-5	hSpCas9	negative selection	4667029
30447780	30447802	10	+	27760321	HL60	viability	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	0.02714681700652466	[294,258]	[249,208]	0	hSpCas9	negative selection	4667030
30447820	30447842	10	+	27760321	HL60	viability	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	0.08307139252376028	[1198,1068]	[891,1072]	1	hSpCas9	negative selection	4667031
30450308	30450330	10	-	27760321	HL60	viability	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.5839802546278752	[648,557]	[813,654]	7	hSpCas9	negative selection	4667032
30439053	30439075	10	-	27760321	HT1080	viability	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	-0.5857148132877711	[485,378]	[99,130]	-3	hSpCas9	negative selection	4750491
30439149	30439171	10	-	27760321	HT1080	viability	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	1.8278748871839865	[280,218]	[406,294]	8	hSpCas9	negative selection	4750492
30447780	30447802	10	+	27760321	HT1080	viability	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	0.4190706711862876	[258,201]	[138,104]	2	hSpCas9	negative selection	4750493
30447820	30447842	10	+	27760321	HT1080	viability	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	1.0994425900470075	[1068,833]	[425,1234]	6	hSpCas9	negative selection	4750494
30450308	30450330	10	-	27760321	HT1080	viability	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.4202740530638743	[557,435]	[83,217]	-2	hSpCas9	negative selection	4750495
30439053	30439075	10	-	27760321	HT29	viability after 7 days	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	-0.3144631270826982	[485,378]	[534,583,240]	-4	hSpCas9	negative selection	4833954
30439149	30439171	10	-	27760321	HT29	viability after 7 days	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.20489241023491273	[280,218]	[282,338,472]	3	hSpCas9	negative selection	4833955
30447780	30447802	10	+	27760321	HT29	viability after 7 days	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	0.675353003013504	[258,201]	[808,344,317]	8	hSpCas9	negative selection	4833956
30447820	30447842	10	+	27760321	HT29	viability after 7 days	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	0.36486804085501867	[1068,833]	[1612,1694,1425]	5	hSpCas9	negative selection	4833957
30450308	30450330	10	-	27760321	HT29	viability after 7 days	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.42196279722082786	[557,435]	[730,528,214]	-6	hSpCas9	negative selection	4833958
30439053	30439075	10	-	27760321	HT29	viability after 25 days	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	0.2278377753674905	[485,378]	[563,476,708]	2	hSpCas9	negative selection	4917417
30439149	30439171	10	-	27760321	HT29	viability after 25 days	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.6823498632616589	[280,218]	[305,440,657]	7	hSpCas9	negative selection	4917418
30447780	30447802	10	+	27760321	HT29	viability after 25 days	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	1.1839751201860953	[258,201]	[520,441,863]	9	hSpCas9	negative selection	4917419
30447820	30447842	10	+	27760321	HT29	viability after 25 days	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	0.3676885689311229	[1068,833]	[1149,1504,1586]	4	hSpCas9	negative selection	4917420
30450308	30450330	10	-	27760321	HT29	viability after 25 days	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.03095488958699566	[557,435]	[505,609,553]	0	hSpCas9	negative selection	4917421
30439053	30439075	10	-	27760321	HT29	viability after 22 days	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	0.05009465639188643	[485,378]	[298,614,645]	0	hSpCas9	negative selection	5000880
30439149	30439171	10	-	27760321	HT29	viability after 22 days	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.42236818815715765	[280,218]	[163,496,507]	4	hSpCas9	negative selection	5000881
30447780	30447802	10	+	27760321	HT29	viability after 22 days	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	1.0315463386551478	[258,201]	[485,568,580]	9	hSpCas9	negative selection	5000882
30447820	30447842	10	+	27760321	HT29	viability after 22 days	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	0.22459996464634857	[1068,833]	[1059,1492,1308]	2	hSpCas9	negative selection	5000883
30450308	30450330	10	-	27760321	HT29	viability after 22 days	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.01562967409420457	[557,435]	[689,642,366]	0	hSpCas9	negative selection	5000884
30439053	30439075	10	-	27760321	HT29	viability after 19 days	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	-0.1414478884619117	[485,378]	[428,520,394]	-1	hSpCas9	negative selection	5084343
30439149	30439171	10	-	27760321	HT29	viability after 19 days	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	-0.08047663592186505	[280,218]	[221,342,241]	0	hSpCas9	negative selection	5084344
30447780	30447802	10	+	27760321	HT29	viability after 19 days	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	1.19917777516027	[258,201]	[832,421,584]	9	hSpCas9	negative selection	5084345
30447820	30447842	10	+	27760321	HT29	viability after 19 days	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	0.4387909342198195	[1068,833]	[1460,2088,894]	4	hSpCas9	negative selection	5084346
30450308	30450330	10	-	27760321	HT29	viability after 19 days	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.33882162274127536	[557,435]	[750,832,580]	3	hSpCas9	negative selection	5084347
30439053	30439075	10	-	27760321	HT29	viability after 16 days	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	-0.03130260003094998	[485,378]	[397,519,493]	0	hSpCas9	negative selection	5167806
30439149	30439171	10	-	27760321	HT29	viability after 16 days	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.49270626301523907	[280,218]	[317,369,485]	5	hSpCas9	negative selection	5167807
30447780	30447802	10	+	27760321	HT29	viability after 16 days	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	1.1543668458674048	[258,201]	[521,457,739]	9	hSpCas9	negative selection	5167808
30447820	30447842	10	+	27760321	HT29	viability after 16 days	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	-0.0067039552764092125	[1068,833]	[1019,1129,1022]	0	hSpCas9	negative selection	5167809
30450308	30450330	10	-	27760321	HT29	viability after 16 days	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.04950605466597674	[557,435]	[589,608,415]	0	hSpCas9	negative selection	5167810
30439053	30439075	10	-	27760321	HT29	viability after 13 days	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	0.13726250955511776	[485,378]	[642,509,504]	1	hSpCas9	negative selection	5251269
30439149	30439171	10	-	27760321	HT29	viability after 13 days	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.23352219373880168	[280,218]	[263,264,484]	3	hSpCas9	negative selection	5251270
30447780	30447802	10	+	27760321	HT29	viability after 13 days	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	1.0247284076487795	[258,201]	[509,644,480]	9	hSpCas9	negative selection	5251271
30447820	30447842	10	+	27760321	HT29	viability after 13 days	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	0.2708828918458712	[1068,833]	[1267,1270,1448]	3	hSpCas9	negative selection	5251272
30450308	30450330	10	-	27760321	HT29	viability after 13 days	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.2286100055482101	[557,435]	[517,530,430]	-3	hSpCas9	negative selection	5251273
30439053	30439075	10	-	27760321	HT29	viability after 10 days	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	-0.10333722091862182	[485,378]	[438,593,477]	-1	hSpCas9	negative selection	5334732
30439149	30439171	10	-	27760321	HT29	viability after 10 days	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	0.2624404621952151	[280,218]	[267,219,624]	3	hSpCas9	negative selection	5334733
30447780	30447802	10	+	27760321	HT29	viability after 10 days	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	0.7369221785950434	[258,201]	[244,548,642]	8	hSpCas9	negative selection	5334734
30447820	30447842	10	+	27760321	HT29	viability after 10 days	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	0.19412204126065502	[1068,833]	[1291,1308,1471]	2	hSpCas9	negative selection	5334735
30450308	30450330	10	-	27760321	HT29	viability after 10 days	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.22849645846350222	[557,435]	[577,408,596]	-3	hSpCas9	negative selection	5334736
30439053	30439075	10	-	27760321	MOLM13	viability	GACTGGGTTCATAAACTGCTGG	MAP3K8	ENSG00000107968	-0.2475838421159864	[596,485]	[275,238]	-2	hSpCas9	negative selection	5418195
30439149	30439171	10	-	27760321	MOLM13	viability	ATCTGACTGATGACAACCATGG	MAP3K8	ENSG00000107968	1.4902579980250854	[337,280]	[508,470]	9	hSpCas9	negative selection	5418196
30447780	30447802	10	+	27760321	MOLM13	viability	AGGTCATCACTCCCCAAAATGG	MAP3K8	ENSG00000107968	0.8946832613022777	[294,258]	[276,300]	6	hSpCas9	negative selection	5418197
30447820	30447842	10	+	27760321	MOLM13	viability	CGATGTTCTCCTGATCCCCTGG	MAP3K8	ENSG00000107968	0.5439910387156397	[1198,1068]	[1139,753]	4	hSpCas9	negative selection	5418198
30450308	30450330	10	-	27760321	MOLM13	viability	CTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.01629807734462485	[648,557]	[277,398]	0	hSpCas9	negative selection	5418199
30434121	30434144	10	+	27661255	K562	viability	GCTCAGACGCCGTGAGTCAGGGG	MAP3K8	ENSG00000107968	0.025681881981995502	[204,250]	[201,169]	0	dCas9-KRAB	negative selection	5492121
30434202	30434225	10	+	27661255	K562	viability	GGACTGCGCGCCACGCTCTGGGG	MAP3K8	ENSG00000107968	-0.004908110829951462	[392,394]	[392,245]	0	dCas9-KRAB	negative selection	5492122
30434190	30434213	10	-	27661255	K562	viability	GCGCGCAGTCCAGAGCGGAGCGG	MAP3K8	ENSG00000107968	-0.011487181752095232	[551,645]	[434,505]	0	dCas9-KRAB	negative selection	5492123
30434195	30434218	10	-	27661255	K562	viability	GCGTGGCGCGCAGTCCAGAGCGG	MAP3K8	ENSG00000107968	0.2722477093660994	[663,807]	[828,603]	8	dCas9-KRAB	negative selection	5492124
30434259	30434282	10	-	27661255	K562	viability	GCCGGGCCACTGGGATCCGGCGG	MAP3K8	ENSG00000107968	0.17267359029160345	[278,327]	[299,248]	6	dCas9-KRAB	negative selection	5492125
30447808	30447831	10	-	27260156	BXPC3	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.5290975460750487	[90]	[118,117,153,163]	9	hSpCas9	negative selection	5554321
30458187	30458210	10	-	27260156	BXPC3	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.0598955598058312	[445]	[454,501,521,461]	1	hSpCas9	negative selection	5554322
30450308	30450331	10	-	27260156	BXPC3	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.04809336926868955	[490]	[431,429,515,632]	-1	hSpCas9	negative selection	5554323
30447872	30447895	10	+	27260156	BXPC3	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.23629743346267262	[767]	[826,882,977,1128]	5	hSpCas9	negative selection	5618579
30458223	30458246	10	-	27260156	BXPC3	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.30505163053627804	[538]	[383,463,476,510]	-6	hSpCas9	negative selection	5618580
30450503	30450526	10	-	27260156	BXPC3	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.211050763258807	[363]	[304,321,330,361]	-5	hSpCas9	negative selection	5618581
30447808	30447831	10	-	27260156	A673	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.5311018772731175	[90]	[129,192,134,169]	9	hSpCas9	negative selection	5675572
30458187	30458210	10	-	27260156	A673	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.09635412384203801	[445]	[578,608,529,570]	2	hSpCas9	negative selection	5675573
30450308	30450331	10	-	27260156	A673	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.0024913060527960093	[490]	[661,526,659,508]	0	hSpCas9	negative selection	5675574
30447872	30447895	10	+	27260156	A673	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.054078392101876704	[767]	[1070,804,984,984]	1	hSpCas9	negative selection	5739830
30458223	30458246	10	-	27260156	A673	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.26823914572223717	[538]	[601,469,512,574]	-6	hSpCas9	negative selection	5739831
30450503	30450526	10	-	27260156	A673	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.04352272325624745	[363]	[428,313,456,502]	-1	hSpCas9	negative selection	5739832
30447808	30447831	10	-	27260156	A375	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.20039626819844525	[90]	[146,177,122,55]	3	hSpCas9	negative selection	5796823
30458187	30458210	10	-	27260156	A375	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	-0.2107922052547478	[445]	[337,465,572,425]	-3	hSpCas9	negative selection	5796824
30450308	30450331	10	-	27260156	A375	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.16704871220368434	[490]	[508,555,624,373]	-2	hSpCas9	negative selection	5796825
30447872	30447895	10	+	27260156	A375	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.45847775577676153	[767]	[1139,1444,1271,1111]	6	hSpCas9	negative selection	5861081
30458223	30458246	10	-	27260156	A375	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	0.0971752266484644	[538]	[704,795,715,510]	1	hSpCas9	negative selection	5861082
30450503	30450526	10	-	27260156	A375	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	0.08145161767034143	[363]	[784,539,290,223]	1	hSpCas9	negative selection	5861083
30447808	30447831	10	-	27260156	COLO741	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.6940690580656239	[90]	[162,240,159]	9	hSpCas9	negative selection	5918074
30458187	30458210	10	-	27260156	COLO741	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.23875566392797526	[445]	[771,760,503]	5	hSpCas9	negative selection	5918075
30450308	30450331	10	-	27260156	COLO741	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.13829136888251098	[490]	[682,803,589]	3	hSpCas9	negative selection	5918076
30447872	30447895	10	+	27260156	COLO741	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.37582046658485047	[767]	[1262,1249,1300]	7	hSpCas9	negative selection	5982332
30458223	30458246	10	-	27260156	COLO741	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.15502761819804528	[538]	[611,697,548]	-3	hSpCas9	negative selection	5982333
30450503	30450526	10	-	27260156	COLO741	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.17952396138548476	[363]	[434,413,385]	-4	hSpCas9	negative selection	5982334
30447808	30447831	10	-	27260156	CAL120	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.4978011931423565	[90]	[309,75,116]	7	hSpCas9	negative selection	6039325
30458187	30458210	10	-	27260156	CAL120	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.14890215260898015	[445]	[747,517,599]	2	hSpCas9	negative selection	6039326
30450308	30450331	10	-	27260156	CAL120	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.27139173970444463	[490]	[410,523,567]	-4	hSpCas9	negative selection	6039327
30447872	30447895	10	+	27260156	CAL120	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.48523338712150677	[767]	[1250,1592,1158]	7	hSpCas9	negative selection	6103583
30458223	30458246	10	-	27260156	CAL120	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.10207337873531835	[538]	[296,783,741]	-1	hSpCas9	negative selection	6103584
30450503	30450526	10	-	27260156	CAL120	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	0.15284973647348263	[363]	[366,787,337]	2	hSpCas9	negative selection	6103585
30447808	30447831	10	-	27260156	CADOES1	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.43096902956136374	[90]	[47,161,123,122]	7	hSpCas9	negative selection	6160576
30458187	30458210	10	-	27260156	CADOES1	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	-0.16460128584953093	[445]	[265,505,360,346]	-3	hSpCas9	negative selection	6160577
30450308	30450331	10	-	27260156	CADOES1	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.047392889561811175	[490]	[384,479,379,525]	-1	hSpCas9	negative selection	6160578
30447872	30447895	10	+	27260156	CADOES1	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.5055766597018952	[767]	[992,1137,900,1024]	8	hSpCas9	negative selection	6224834
30458223	30458246	10	-	27260156	CADOES1	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.3514028460586178	[538]	[416,487,321,342]	-6	hSpCas9	negative selection	6224835
30450503	30450526	10	-	27260156	CADOES1	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.29660727148440236	[363]	[318,319,200,261]	-5	hSpCas9	negative selection	6224836
30447808	30447831	10	-	27260156	EWS502	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.060482105932004426	[90]	[132,75,113,73]	1	hSpCas9	negative selection	6281827
30458187	30458210	10	-	27260156	EWS502	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.00488522722138042	[445]	[547,399,434,506]	0	hSpCas9	negative selection	6281828
30450308	30450331	10	-	27260156	EWS502	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.026141238233487324	[490]	[375,504,560,706]	0	hSpCas9	negative selection	6281829
30447872	30447895	10	+	27260156	EWS502	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.190739503463211	[767]	[851,790,837,1266]	3	hSpCas9	negative selection	6346085
30458223	30458246	10	-	27260156	EWS502	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	0.0714417788752803	[538]	[580,515,761,541]	1	hSpCas9	negative selection	6346086
30450503	30450526	10	-	27260156	EWS502	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.4826684832072674	[363]	[217,217,316,365]	-7	hSpCas9	negative selection	6346087
30447808	30447831	10	-	27260156	EW8	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	-0.13086225001150442	[90]	[87,96,23,69]	-2	hSpCas9	negative selection	6403078
30458187	30458210	10	-	27260156	EW8	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.0710876126788306	[445]	[538,405,240,372]	1	hSpCas9	negative selection	6403079
30450308	30450331	10	-	27260156	EW8	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.10675670080683644	[490]	[442,399,312,338]	-2	hSpCas9	negative selection	6403080
30447872	30447895	10	+	27260156	EW8	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.18750360648211628	[767]	[850,827,618,566]	3	hSpCas9	negative selection	6467336
30458223	30458246	10	-	27260156	EW8	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.6426550291791671	[538]	[360,280,204,292]	-8	hSpCas9	negative selection	6467337
30450503	30450526	10	-	27260156	EW8	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.1420789524054874	[363]	[271,232,235,332]	-3	hSpCas9	negative selection	6467338
30447808	30447831	10	-	27260156	CORL105	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.5792934617268808	[90]	[188,191,194,66]	9	hSpCas9	negative selection	6524329
30458187	30458210	10	-	27260156	CORL105	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.005490269222805974	[445]	[677,423,581,428]	0	hSpCas9	negative selection	6524330
30450308	30450331	10	-	27260156	CORL105	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.11861299013155044	[490]	[591,399,1059,515]	2	hSpCas9	negative selection	6524331
30447872	30447895	10	+	27260156	CORL105	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.33983031747740367	[767]	[1073,1027,1372,1112]	6	hSpCas9	negative selection	6588587
30458223	30458246	10	-	27260156	CORL105	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.3417956591396305	[538]	[492,452,535,515]	-6	hSpCas9	negative selection	6588588
30450503	30450526	10	-	27260156	CORL105	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.255295860964453	[363]	[359,336,360,370]	-5	hSpCas9	negative selection	6588589
30447808	30447831	10	-	27260156	HS294T	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.3247356400884849	[90]	[61,39,25,46]	4	hSpCas9	negative selection	6645580
30458187	30458210	10	-	27260156	HS294T	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	-0.06860661064090476	[445]	[137,208,162,144]	-1	hSpCas9	negative selection	6645581
30450308	30450331	10	-	27260156	HS294T	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.6093803450122959	[490]	[270,151,196,594]	7	hSpCas9	negative selection	6645582
30447872	30447895	10	+	27260156	HS294T	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	-0.46210314931607555	[767]	[178,142,152,427]	-6	hSpCas9	negative selection	6709838
30458223	30458246	10	-	27260156	HS294T	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.6954093057566766	[538]	[103,103,133,184]	-7	hSpCas9	negative selection	6709839
30450503	30450526	10	-	27260156	HS294T	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	0.4481349358727509	[363]	[232,154,137,247]	6	hSpCas9	negative selection	6709840
30447808	30447831	10	-	27260156	HCC44	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.49655383772797945	[90]	[186,59,256,111]	7	hSpCas9	negative selection	6766831
30458187	30458210	10	-	27260156	HCC44	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.3176735496414821	[445]	[733,507,632,660]	5	hSpCas9	negative selection	6766832
30450308	30450331	10	-	27260156	HCC44	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.1256138225423375	[490]	[454,411,660,537]	-2	hSpCas9	negative selection	6766833
30447872	30447895	10	+	27260156	HCC44	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	-0.07437389816613171	[767]	[944,696,933,766]	-1	hSpCas9	negative selection	6831089
30458223	30458246	10	-	27260156	HCC44	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.10759377113296624	[538]	[538,615,479,597]	-2	hSpCas9	negative selection	6831090
30450503	30450526	10	-	27260156	HCC44	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	0.11032650640768699	[363]	[328,598,545,289]	1	hSpCas9	negative selection	6831091
30447808	30447831	10	-	27260156	G402	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.5836383062407695	[90]	[115,183,49,301]	7	hSpCas9	negative selection	6888082
30458187	30458210	10	-	27260156	G402	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	-0.27034781327516527	[445]	[396,612,540,262]	-3	hSpCas9	negative selection	6888083
30450308	30450331	10	-	27260156	G402	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.08520118887107461	[490]	[502,394,746,850]	1	hSpCas9	negative selection	6888084
30447872	30447895	10	+	27260156	G402	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.7971865558358014	[767]	[1849,1078,2130,1455]	8	hSpCas9	negative selection	6952340
30458223	30458246	10	-	27260156	G402	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.43023823298988606	[538]	[583,611,381,397]	-5	hSpCas9	negative selection	6952341
30450503	30450526	10	-	27260156	G402	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.16105882341880828	[363]	[265,544,367,397]	-2	hSpCas9	negative selection	6952342
30447808	30447831	10	-	27260156	L33	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	-0.3691415654160459	[90]	[79,19,67,44]	-7	hSpCas9	negative selection	7009333
30458187	30458210	10	-	27260156	L33	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.03648924126786679	[445]	[438,189,310,432]	0	hSpCas9	negative selection	7009334
30450308	30450331	10	-	27260156	L33	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.29723753179743917	[490]	[678,231,379,561]	6	hSpCas9	negative selection	7009335
30447872	30447895	10	+	27260156	L33	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	-0.3382944092498975	[767]	[669,222,341,668]	-7	hSpCas9	negative selection	7073591
30458223	30458246	10	-	27260156	L33	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.3081084384224073	[538]	[365,205,249,475]	-6	hSpCas9	negative selection	7073592
30450503	30450526	10	-	27260156	L33	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.2646821472301717	[363]	[275,123,253,230]	-6	hSpCas9	negative selection	7073593
30447808	30447831	10	-	27260156	K562	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	-0.32412252337763103	[90]	[87,98,61,17]	-4	hSpCas9	negative selection	7130584
30458187	30458210	10	-	27260156	K562	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.16564208023145863	[445]	[532,482,339,428]	2	hSpCas9	negative selection	7130585
30450308	30450331	10	-	27260156	K562	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.3738261804143177	[490]	[839,421,622,404]	5	hSpCas9	negative selection	7130586
30447872	30447895	10	+	27260156	K562	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.6177856258441902	[767]	[856,944,1723,675]	7	hSpCas9	negative selection	7194842
30458223	30458246	10	-	27260156	K562	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.3332249880625415	[538]	[324,427,201,540]	-4	hSpCas9	negative selection	7194843
30450503	30450526	10	-	27260156	K562	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.14546598196092564	[363]	[220,392,265,286]	-2	hSpCas9	negative selection	7194844
30447808	30447831	10	-	27260156	HT29	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.5374844485604884	[90]	[149,221,188,92]	9	hSpCas9	negative selection	7251835
30458187	30458210	10	-	27260156	HT29	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	-0.017705546055076293	[445]	[536,522,511,561]	0	hSpCas9	negative selection	7251836
30450308	30450331	10	-	27260156	HT29	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.2930220807053058	[490]	[804,707,719,694]	6	hSpCas9	negative selection	7251837
30447872	30447895	10	+	27260156	HT29	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.26697254524551994	[767]	[1221,1167,1057,1056]	5	hSpCas9	negative selection	7316093
30458223	30458246	10	-	27260156	HT29	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.040435940724571656	[538]	[657,767,532,601]	-1	hSpCas9	negative selection	7316094
30450503	30450526	10	-	27260156	HT29	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.108532618670867	[363]	[671,447,346,218]	-2	hSpCas9	negative selection	7316095
30447808	30447831	10	-	27260156	MHHES1	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.09666003549177704	[90]	[161,170,117,18]	1	hSpCas9	negative selection	7373086
30458187	30458210	10	-	27260156	MHHES1	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	-0.042631441313848176	[445]	[568,610,396,403]	-1	hSpCas9	negative selection	7373087
30450308	30450331	10	-	27260156	MHHES1	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.15217960062991964	[490]	[859,723,418,505]	3	hSpCas9	negative selection	7373088
30447872	30447895	10	+	27260156	MHHES1	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.13532786952790676	[767]	[1074,1063,890,807]	2	hSpCas9	negative selection	7437344
30458223	30458246	10	-	27260156	MHHES1	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.36077258518478295	[538]	[529,624,495,293]	-6	hSpCas9	negative selection	7437345
30450503	30450526	10	-	27260156	MHHES1	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	0.07404035626891864	[363]	[593,382,573,228]	1	hSpCas9	negative selection	7437346
30447808	30447831	10	-	27260156	MEWO	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.44335913382403125	[90]	[180,96,81]	8	hSpCas9	negative selection	7494337
30458187	30458210	10	-	27260156	MEWO	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.37481982346508136	[445]	[563,434,628]	7	hSpCas9	negative selection	7494338
30450308	30450331	10	-	27260156	MEWO	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.1669122460332057	[490]	[513,355,377]	-4	hSpCas9	negative selection	7494339
30447872	30447895	10	+	27260156	MEWO	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.1638146443080154	[767]	[941,826,671]	3	hSpCas9	negative selection	7558595
30458223	30458246	10	-	27260156	MEWO	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	0.363708033045587	[538]	[1118,342,576]	7	hSpCas9	negative selection	7558596
30450503	30450526	10	-	27260156	MEWO	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.10620845353815894	[363]	[458,251,265]	-2	hSpCas9	negative selection	7558597
30447808	30447831	10	-	27260156	LNCAPCLONEFGC	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.5206696479995634	[90]	[77,120,100,170]	7	hSpCas9	negative selection	7615588
30458187	30458210	10	-	27260156	LNCAPCLONEFGC	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.14192857241160062	[445]	[379,335,557,533]	2	hSpCas9	negative selection	7615589
30450308	30450331	10	-	27260156	LNCAPCLONEFGC	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.059109770105640405	[490]	[555,229,659,449]	0	hSpCas9	negative selection	7615590
30447872	30447895	10	+	27260156	LNCAPCLONEFGC	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.4458775536995282	[767]	[1024,850,975,946]	7	hSpCas9	negative selection	7679846
30458223	30458246	10	-	27260156	LNCAPCLONEFGC	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.18246826117141324	[538]	[384,471,417,441]	-3	hSpCas9	negative selection	7679847
30450503	30450526	10	-	27260156	LNCAPCLONEFGC	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	0.11004318480746844	[363]	[350,214,573,324]	1	hSpCas9	negative selection	7679848
30447808	30447831	10	-	27260156	PANC0327	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	-0.17255905570337404	[90]	[113,26,27,126]	-3	hSpCas9	negative selection	7736839
30458187	30458210	10	-	27260156	PANC0327	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.1466659946993652	[445]	[564,228,636,360]	2	hSpCas9	negative selection	7736840
30450308	30450331	10	-	27260156	PANC0327	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.1307559199819829	[490]	[385,324,506,383]	-2	hSpCas9	negative selection	7736841
30447872	30447895	10	+	27260156	PANC0327	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.45124273887962174	[767]	[960,680,1212,910]	6	hSpCas9	negative selection	7801097
30458223	30458246	10	-	27260156	PANC0327	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	0.025261796920115792	[538]	[488,285,550,648]	0	hSpCas9	negative selection	7801098
30450503	30450526	10	-	27260156	PANC0327	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.26193089394906777	[363]	[221,162,138,563]	-4	hSpCas9	negative selection	7801099
30447808	30447831	10	-	27260156	NCIH2009	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.8847004833474954	[90]	[130,308,241]	9	hSpCas9	negative selection	7858090
30458187	30458210	10	-	27260156	NCIH2009	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	-0.11249014280246913	[445]	[845,547,387]	-1	hSpCas9	negative selection	7858091
30450308	30450331	10	-	27260156	NCIH2009	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.33436954847858075	[490]	[1045,650,935]	4	hSpCas9	negative selection	7858092
30447872	30447895	10	+	27260156	NCIH2009	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.10157263799385252	[767]	[1320,1285,875]	1	hSpCas9	negative selection	7922348
30458223	30458246	10	-	27260156	NCIH2009	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.5103899257249221	[538]	[572,522,497]	-6	hSpCas9	negative selection	7922349
30450503	30450526	10	-	27260156	NCIH2009	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.23178714213007268	[363]	[437,514,344]	-3	hSpCas9	negative selection	7922350
30447808	30447831	10	-	27260156	NCIH1373	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.8750118816637349	[90]	[267,97,142,69]	8	hSpCas9	negative selection	7979341
30458187	30458210	10	-	27260156	NCIH1373	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.34026296147451773	[445]	[502,542,404,288]	3	hSpCas9	negative selection	7979342
30450308	30450331	10	-	27260156	NCIH1373	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.500428652509434	[490]	[518,306,407,90]	-5	hSpCas9	negative selection	7979343
30447872	30447895	10	+	27260156	NCIH1373	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.5297065531352286	[767]	[1261,857,1275,429]	5	hSpCas9	negative selection	8043599
30458223	30458246	10	-	27260156	NCIH1373	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	0.16775701069012072	[538]	[771,448,977,140]	1	hSpCas9	negative selection	8043600
30450503	30450526	10	-	27260156	NCIH1373	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.8245713755135102	[363]	[126,233,147,106]	-7	hSpCas9	negative selection	8043601
30447808	30447831	10	-	27260156	PATU8902	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.842757962652197	[90]	[342,234,77,296]	8	hSpCas9	negative selection	8100592
30458187	30458210	10	-	27260156	PATU8902	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.20441074219848826	[445]	[625,793,595,894]	2	hSpCas9	negative selection	8100593
30450308	30450331	10	-	27260156	PATU8902	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.14507117864245656	[490]	[559,828,650,1042]	1	hSpCas9	negative selection	8100594
30447872	30447895	10	+	27260156	PATU8902	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.6378183720887179	[767]	[2503,1508,948,1881]	6	hSpCas9	negative selection	8164850
30458223	30458246	10	-	27260156	PATU8902	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.36484309277299287	[538]	[645,661,344,755]	-4	hSpCas9	negative selection	8164851
30450503	30450526	10	-	27260156	PATU8902	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	0.036675844789630596	[363]	[520,568,467,532]	0	hSpCas9	negative selection	8164852
30447808	30447831	10	-	27260156	PANC1	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	-0.21259411090227553	[90]	[96,47,38,77]	-3	hSpCas9	negative selection	8221843
30458187	30458210	10	-	27260156	PANC1	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.08888975376965796	[445]	[278,494,514,362]	1	hSpCas9	negative selection	8221844
30450308	30450331	10	-	27260156	PANC1	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.3767184522567371	[490]	[361,331,347,262]	-5	hSpCas9	negative selection	8221845
30447872	30447895	10	+	27260156	PANC1	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.23566266465866048	[767]	[704,964,909,586]	4	hSpCas9	negative selection	8286101
30458223	30458246	10	-	27260156	PANC1	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.2750393120137104	[538]	[352,334,554,288]	-4	hSpCas9	negative selection	8286102
30450503	30450526	10	-	27260156	PANC1	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.024401380276854345	[363]	[349,352,253,279]	0	hSpCas9	negative selection	8286103
30447808	30447831	10	-	27260156	PANC0813	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.962673120673571	[90]	[185,279,128,233]	9	hSpCas9	negative selection	8343094
30458187	30458210	10	-	27260156	PANC0813	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	-0.048812119647723445	[445]	[586,336,464,635]	-1	hSpCas9	negative selection	8343095
30450308	30450331	10	-	27260156	PANC0813	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.3599362057688848	[490]	[681,767,605,888]	6	hSpCas9	negative selection	8343096
30447872	30447895	10	+	27260156	PANC0813	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.1080683661484243	[767]	[1037,1136,1097,639]	1	hSpCas9	negative selection	8407352
30458223	30458246	10	-	27260156	PANC0813	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.11448798315899597	[538]	[662,540,582,559]	-2	hSpCas9	negative selection	8407353
30450503	30450526	10	-	27260156	PANC0813	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.2734308080862552	[363]	[362,286,315,443]	-4	hSpCas9	negative selection	8407354
30447808	30447831	10	-	27260156	RDES	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.4620831418456435	[90]	[82,126,174,214]	7	hSpCas9	negative selection	8464345
30458187	30458210	10	-	27260156	RDES	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.2021200058875921	[445]	[493,540,546,818]	3	hSpCas9	negative selection	8464346
30450308	30450331	10	-	27260156	RDES	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.16525254466508071	[490]	[515,548,591,934]	2	hSpCas9	negative selection	8464347
30447872	30447895	10	+	27260156	RDES	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.34568500148215653	[767]	[974,1026,1349,1156]	5	hSpCas9	negative selection	8528603
30458223	30458246	10	-	27260156	RDES	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.3348161671797133	[538]	[401,425,475,704]	-5	hSpCas9	negative selection	8528604
30450503	30450526	10	-	27260156	RDES	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.33883105527300883	[363]	[298,278,358,399]	-5	hSpCas9	negative selection	8528605
30447808	30447831	10	-	27260156	PC3	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	-0.10831269241081642	[90]	[82,97,104,43]	-2	hSpCas9	negative selection	8585596
30458187	30458210	10	-	27260156	PC3	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.019685824109574396	[445]	[313,326,850,487]	0	hSpCas9	negative selection	8585597
30450308	30450331	10	-	27260156	PC3	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.13088449643796018	[490]	[244,429,901,438]	-3	hSpCas9	negative selection	8585598
30447872	30447895	10	+	27260156	PC3	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.22532899674929652	[767]	[604,985,1619,668]	5	hSpCas9	negative selection	8649854
30458223	30458246	10	-	27260156	PC3	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.36412006788159695	[538]	[361,420,512,377]	-7	hSpCas9	negative selection	8649855
30450503	30450526	10	-	27260156	PC3	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.4619681239233744	[363]	[192,201,516,244]	-8	hSpCas9	negative selection	8649856
30447808	30447831	10	-	27260156	PATU8988T	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.45706951598083667	[90]	[44,150,89,206]	7	hSpCas9	negative selection	8706847
30458187	30458210	10	-	27260156	PATU8988T	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.34798843233732824	[445]	[767,853,199,392]	6	hSpCas9	negative selection	8706848
30450308	30450331	10	-	27260156	PATU8988T	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.01504567716331702	[490]	[339,573,558,449]	0	hSpCas9	negative selection	8706849
30447872	30447895	10	+	27260156	PATU8988T	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.130086057485165	[767]	[881,1098,689,587]	2	hSpCas9	negative selection	8771105
30458223	30458246	10	-	27260156	PATU8988T	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.11703311774111823	[538]	[267,429,398,849]	-2	hSpCas9	negative selection	8771106
30450503	30450526	10	-	27260156	PATU8988T	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.11050430714834752	[363]	[288,309,404,293]	-2	hSpCas9	negative selection	8771107
30447808	30447831	10	-	27260156	T47D	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.3912479373232549	[90]	[128,183,115,122]	8	hSpCas9	negative selection	8828098
30458187	30458210	10	-	27260156	T47D	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.11628994311931878	[445]	[500,590,541,617]	2	hSpCas9	negative selection	8828099
30450308	30450331	10	-	27260156	T47D	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	-0.013525619576505492	[490]	[668,475,580,547]	0	hSpCas9	negative selection	8828100
30447872	30447895	10	+	27260156	T47D	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.26685512575179915	[767]	[1062,991,1124,1133]	5	hSpCas9	negative selection	8892356
30458223	30458246	10	-	27260156	T47D	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.2639420238937662	[538]	[544,479,608,457]	-5	hSpCas9	negative selection	8892357
30450503	30450526	10	-	27260156	T47D	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.025190262575769007	[363]	[486,292,475,420]	0	hSpCas9	negative selection	8892358
30447808	30447831	10	-	27260156	SU8686	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.3336197128594698	[90]	[97,101,144,112]	5	hSpCas9	negative selection	8949349
30458187	30458210	10	-	27260156	SU8686	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.06835658143059326	[445]	[417,506,483,437]	1	hSpCas9	negative selection	8949350
30450308	30450331	10	-	27260156	SU8686	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.03373759343304229	[490]	[551,512,459,446]	0	hSpCas9	negative selection	8949351
30447872	30447895	10	+	27260156	SU8686	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	-0.12095242396968542	[767]	[645,555,748,903]	-2	hSpCas9	negative selection	9013607
30458223	30458246	10	-	27260156	SU8686	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.39018880829903624	[538]	[264,415,355,642]	-6	hSpCas9	negative selection	9013608
30450503	30450526	10	-	27260156	SU8686	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.037543581865019826	[363]	[383,317,278,434]	0	hSpCas9	negative selection	9013609
30447808	30447831	10	-	27260156	SKES1	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.07422071349838566	[90]	[73,106,138,62]	1	hSpCas9	negative selection	9070600
30458187	30458210	10	-	27260156	SKES1	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.0029338992533208125	[445]	[335,442,529,451]	0	hSpCas9	negative selection	9070601
30450308	30450331	10	-	27260156	SKES1	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.010726947838405054	[490]	[485,508,402,563]	0	hSpCas9	negative selection	9070602
30447872	30447895	10	+	27260156	SKES1	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.33223721264796724	[767]	[1073,982,764,1036]	7	hSpCas9	negative selection	9134858
30458223	30458246	10	-	27260156	SKES1	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.224645289774571	[538]	[492,510,472,378]	-5	hSpCas9	negative selection	9134859
30450503	30450526	10	-	27260156	SKES1	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.1937415781572176	[363]	[313,318,354,281]	-4	hSpCas9	negative selection	9134860
30447808	30447831	10	-	27260156	TOV112D	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.6166422423048892	[90]	[89,221,129,132]	9	hSpCas9	negative selection	9191851
30458187	30458210	10	-	27260156	TOV112D	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	0.06515329743706366	[445]	[433,660,481,339]	1	hSpCas9	negative selection	9191852
30450308	30450331	10	-	27260156	TOV112D	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.2539550562835097	[490]	[421,678,788,466]	5	hSpCas9	negative selection	9191853
30447872	30447895	10	+	27260156	TOV112D	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.17109196936330218	[767]	[712,1176,865,772]	3	hSpCas9	negative selection	9256109
30458223	30458246	10	-	27260156	TOV112D	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	0.12668635452089072	[538]	[672,479,605,577]	2	hSpCas9	negative selection	9256110
30450503	30450526	10	-	27260156	TOV112D	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.21898725932928775	[363]	[316,482,272,223]	-4	hSpCas9	negative selection	9256111
30447808	30447831	10	-	27260156	TC71	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.010122911995460449	[90]	[87,124,108,68]	0	hSpCas9	negative selection	9313102
30458187	30458210	10	-	27260156	TC71	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	-0.16323593304702924	[445]	[384,465,425,431]	-4	hSpCas9	negative selection	9313103
30450308	30450331	10	-	27260156	TC71	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.05572083818338816	[490]	[562,515,474,641]	1	hSpCas9	negative selection	9313104
30447872	30447895	10	+	27260156	TC71	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	-0.1256625440833724	[767]	[849,868,676,613]	-3	hSpCas9	negative selection	9377360
30458223	30458246	10	-	27260156	TC71	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.22041482666018236	[538]	[451,430,483,625]	-5	hSpCas9	negative selection	9377361
30450503	30450526	10	-	27260156	TC71	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.002573272182994135	[363]	[406,326,403,420]	0	hSpCas9	negative selection	9377362
30447808	30447831	10	-	27260156	TC32	viability	GGAGAACATCGGAATCTATTTGG	MAP3K8	ENSG00000107968	0.7505419453166353	[90]	[135,72,123,265]	9	hSpCas9	negative selection	9434353
30458187	30458210	10	-	27260156	TC32	viability	GCGAGGGTAGCGCTTCACCCAGG	MAP3K8	ENSG00000107968	-0.19459312106397902	[445]	[550,195,403,336]	-4	hSpCas9	negative selection	9434354
30450308	30450331	10	-	27260156	TC32	viability	GCTCTGCGATGTTCTCGTGCCGG	MAP3K8	ENSG00000107968	0.2141019983611555	[490]	[434,443,716,594]	4	hSpCas9	negative selection	9434355
30447872	30447895	10	+	27260156	TC32	viability	TTTATTCCTCGGGGCGCCTTTGG	MAP3K8	ENSG00000107968	0.49506133236176375	[767]	[800,804,1392,1192]	8	hSpCas9	negative selection	9498611
30458223	30458246	10	-	27260156	TC32	viability	CCCACTTACTATGTACAGGTAGG	MAP3K8	ENSG00000107968	-0.35463368246484817	[538]	[374,257,586,431]	-6	hSpCas9	negative selection	9498612
30450503	30450526	10	-	27260156	TC32	viability	ACTTACGTTTAATATCATGATGG	MAP3K8	ENSG00000107968	-0.6145259510187835	[363]	[174,125,363,287]	-8	hSpCas9	negative selection	9498613
30439124	30439147	10	+	27869803	HPAFII	viability after 27 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.2779847472997652	[497]	[455,201,NaN]	2	hSpCas9	negative selection	9537756
30450296	30450319	10	-	27869803	HPAFII	viability after 27 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	1.0297608491821817	[217]	[263,208,NaN]	8	hSpCas9	negative selection	9537757
30450365	30450388	10	+	27869803	HPAFII	viability after 27 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	-0.8899327787283619	[148]	[38,44,NaN]	-6	hSpCas9	negative selection	9537758
30451723	30451746	10	+	27869803	HPAFII	viability after 27 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.7274374893282667	[232]	[288,130,NaN]	6	hSpCas9	negative selection	9537759
30458154	30458177	10	-	27869803	HPAFII	viability after 27 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.07374266923169309	[323]	[13,316,NaN]	0	hSpCas9	negative selection	9537760
30459440	30459463	10	-	27869803	HPAFII	viability after 27 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.2343072280011903	[178]	[61,94,NaN]	-2	hSpCas9	negative selection	9537761
30439124	30439147	10	+	27869803	HPAFII	viability after 15 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	-0.10226577169016104	[497]	[743,345,NaN]	-1	hSpCas9	negative selection	9620205
30450296	30450319	10	-	27869803	HPAFII	viability after 15 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.2879444306553877	[217]	[417,203,NaN]	3	hSpCas9	negative selection	9620206
30450365	30450388	10	+	27869803	HPAFII	viability after 15 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	0.207094628300455	[148]	[219,162,NaN]	2	hSpCas9	negative selection	9620207
30451723	30451746	10	+	27869803	HPAFII	viability after 15 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.5371601886700388	[232]	[638,191,NaN]	6	hSpCas9	negative selection	9620208
30458154	30458177	10	-	27869803	HPAFII	viability after 15 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	-0.29113633052395715	[323]	[69,417,NaN]	-3	hSpCas9	negative selection	9620209
30459440	30459463	10	-	27869803	HPAFII	viability after 15 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.33971571025370073	[178]	[285,216,NaN]	4	hSpCas9	negative selection	9620210
30439124	30439147	10	+	27869803	ASPC1	viability after 36 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.03910630993541864	[1144]	[564,406,300]	0	hSpCas9	negative selection	9702654
30450296	30450319	10	-	27869803	ASPC1	viability after 36 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	1.1833231809903564	[434]	[765,176,178]	9	hSpCas9	negative selection	9702655
30450365	30450388	10	+	27869803	ASPC1	viability after 36 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	0.6161233775070777	[341]	[167,58,289]	6	hSpCas9	negative selection	9702656
30451723	30451746	10	+	27869803	ASPC1	viability after 36 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.05870384799483322	[711]	[427,295,107]	0	hSpCas9	negative selection	9702657
30458154	30458177	10	-	27869803	ASPC1	viability after 36 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.7079108011960584	[523]	[247,186,419]	7	hSpCas9	negative selection	9702658
30459440	30459463	10	-	27869803	ASPC1	viability after 36 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-1.3827545027041075	[373]	[87,20,45]	-8	hSpCas9	negative selection	9702659
30439124	30439147	10	+	27869803	PATU8988S	viability after 35 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.29029317427671975	[903]	[329,560,NaN]	3	hSpCas9	negative selection	9785103
30450296	30450319	10	-	27869803	PATU8988S	viability after 35 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	-0.11736823951175451	[427]	[118,198,NaN]	-1	hSpCas9	negative selection	9785104
30450365	30450388	10	+	27869803	PATU8988S	viability after 35 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	0.43660156906588343	[340]	[130,240,NaN]	5	hSpCas9	negative selection	9785105
30451723	30451746	10	+	27869803	PATU8988S	viability after 35 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.4364141589261997	[533]	[307,273,NaN]	5	hSpCas9	negative selection	9785106
30458154	30458177	10	-	27869803	PATU8988S	viability after 35 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.5667985485213339	[559]	[148,519,NaN]	6	hSpCas9	negative selection	9785107
30459440	30459463	10	-	27869803	PATU8988S	viability after 35 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.10391716845848309	[353]	[204,59,NaN]	-1	hSpCas9	negative selection	9785108
30439124	30439147	10	+	27869803	PATU8988S	viability after 31 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.3051402065347425	[903]	[286,646,NaN]	4	hSpCas9	negative selection	9867552
30450296	30450319	10	-	27869803	PATU8988S	viability after 31 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	-0.03476698633616693	[427]	[159,174,NaN]	0	hSpCas9	negative selection	9867553
30450365	30450388	10	+	27869803	PATU8988S	viability after 31 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	0.23758619913426932	[340]	[125,203,NaN]	3	hSpCas9	negative selection	9867554
30451723	30451746	10	+	27869803	PATU8988S	viability after 31 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.05213350667243656	[533]	[240,194,NaN]	0	hSpCas9	negative selection	9867555
30458154	30458177	10	-	27869803	PATU8988S	viability after 31 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	0.4849017883127136	[559]	[220,428,NaN]	6	hSpCas9	negative selection	9867556
30459440	30459463	10	-	27869803	PATU8988S	viability after 31 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.1896355656607862	[353]	[165,69,NaN]	-2	hSpCas9	negative selection	9867557
30439124	30439147	10	+	27869803	HPAFII	viability after 35 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.44178871305064993	[497]	[396,280,NaN]	3	hSpCas9	negative selection	9950001
30450296	30450319	10	-	27869803	HPAFII	viability after 35 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.554915353936377	[217]	[187,132,NaN]	3	hSpCas9	negative selection	9950002
30450365	30450388	10	+	27869803	HPAFII	viability after 35 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	-1.9582724349644867	[148]	[17,20,NaN]	-7	hSpCas9	negative selection	9950003
30451723	30451746	10	+	27869803	HPAFII	viability after 35 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	1.6376474212919139	[232]	[541,169,NaN]	9	hSpCas9	negative selection	9950004
30458154	30458177	10	-	27869803	HPAFII	viability after 35 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	-0.22607729817208524	[323]	[16,278,NaN]	-1	hSpCas9	negative selection	9950005
30459440	30459463	10	-	27869803	HPAFII	viability after 35 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.6350224971105958	[178]	[55,60,NaN]	-4	hSpCas9	negative selection	9950006
30439124	30439147	10	+	27869803	HPAFII	viability after 31 days	TCTGCTGCTTAGTGGCCAAGAGG	MAP3K8	ENSG00000107968	0.26743379571923787	[497]	[445,216,NaN]	2	hSpCas9	negative selection	10032450
30450296	30450319	10	-	27869803	HPAFII	viability after 31 days	TCTCGTGCCGGAAGCAAGCCTGG	MAP3K8	ENSG00000107968	0.8761256776864788	[217]	[236,210,NaN]	6	hSpCas9	negative selection	10032451
30450365	30450388	10	+	27869803	HPAFII	viability after 31 days	TCTCTTTATGGAAGCAGGCGAGG	MAP3K8	ENSG00000107968	-1.1646935954190285	[148]	[43,29,NaN]	-6	hSpCas9	negative selection	10032452
30451723	30451746	10	+	27869803	HPAFII	viability after 31 days	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	1.3388447126649683	[232]	[425,226,NaN]	8	hSpCas9	negative selection	10032453
30458154	30458177	10	-	27869803	HPAFII	viability after 31 days	CGTCTGCATGTGGATGAGCGTGG	MAP3K8	ENSG00000107968	-0.2555713534044991	[323]	[2,314,NaN]	-2	hSpCas9	negative selection	10032454
30459440	30459463	10	-	27869803	HPAFII	viability after 31 days	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.41395195920769656	[178]	[61,89,NaN]	-3	hSpCas9	negative selection	10032455
30438936	30438959	10	+	28162770	P31FUJ	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.2424108098938641	[404]	[562]	2	hSpCas9	negative selection	10188864
30450399	30450422	10	+	28162770	P31FUJ	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-0.5547302993017409	[49]	[39]	-5	hSpCas9	negative selection	10188865
30458096	30458119	10	+	28162770	P31FUJ	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	0.6465524415057605	[267]	[492]	7	hSpCas9	negative selection	10188866
30458181	30458204	10	-	28162770	P31FUJ	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	0.7019517709701832	[146]	[280]	7	hSpCas9	negative selection	10188867
30458203	30458226	10	-	28162770	P31FUJ	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	0.21650519694921155	[51]	[70]	2	hSpCas9	negative selection	10188868
30459440	30459463	10	-	28162770	P31FUJ	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	1.0119767917121472	[337]	[800]	9	hSpCas9	negative selection	10188869
30439132	30439155	10	+	28162770	P31FUJ	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.8896974508351969	[535]	[1166]	8	hSpCas9	negative selection	10188870
30451723	30451746	10	+	28162770	P31FUJ	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.15052643513712693	[45]	[59]	1	hSpCas9	negative selection	10188871
30459414	30459437	10	-	28162770	P31FUJ	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	-0.40002082283437157	[465]	[414]	-4	hSpCas9	negative selection	10188872
30459458	30459481	10	+	28162770	P31FUJ	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	0.7221099060570835	[194]	[377]	8	hSpCas9	negative selection	10188873
30438936	30438959	10	+	28162770	TF1	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	NaN	[NaN]	[241]	1	hSpCas9	negative selection	10358230
30450399	30450422	10	+	28162770	TF1	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10358231
30458096	30458119	10	+	28162770	TF1	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	NaN	[NaN]	[308]	1	hSpCas9	negative selection	10358232
30458181	30458204	10	-	28162770	TF1	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	NaN	[NaN]	[151]	1	hSpCas9	negative selection	10358233
30458203	30458226	10	-	28162770	TF1	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10358234
30459440	30459463	10	-	28162770	TF1	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	NaN	[NaN]	[267]	1	hSpCas9	negative selection	10358235
30439132	30439155	10	+	28162770	TF1	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	NaN	[NaN]	[430]	1	hSpCas9	negative selection	10358236
30451723	30451746	10	+	28162770	TF1	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10358237
30459414	30459437	10	-	28162770	TF1	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	NaN	[NaN]	[476]	1	hSpCas9	negative selection	10358238
30459458	30459481	10	+	28162770	TF1	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	NaN	[NaN]	[164]	1	hSpCas9	negative selection	10358239
30438936	30438959	10	+	28162770	SKM1	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.062493535204711126	[126]	[214]	0	hSpCas9	negative selection	10527596
30450399	30450422	10	+	28162770	SKM1	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-1.1115083152169905	[21]	[17]	-7	hSpCas9	negative selection	10527597
30458096	30458119	10	+	28162770	SKM1	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	0.053907954253350376	[90]	[166]	0	hSpCas9	negative selection	10527598
30458181	30458204	10	-	28162770	SKM1	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	-0.21628063713405207	[68]	[104]	-2	hSpCas9	negative selection	10527599
30458203	30458226	10	-	28162770	SKM1	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	0.45363274459142167	[18]	[45]	4	hSpCas9	negative selection	10527600
30459440	30459463	10	-	28162770	SKM1	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.17799830197799427	[107]	[215]	1	hSpCas9	negative selection	10527601
30439132	30439155	10	+	28162770	SKM1	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.7629608026991508	[114]	[344]	7	hSpCas9	negative selection	10527602
30451723	30451746	10	+	28162770	SKM1	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.5930358012568382	[8]	[23]	6	hSpCas9	negative selection	10527603
30459414	30459437	10	-	28162770	SKM1	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.18425729244967703	[114]	[230]	1	hSpCas9	negative selection	10527604
30459458	30459481	10	+	28162770	SKM1	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	-0.19195130777231129	[41]	[64]	-2	hSpCas9	negative selection	10527605
30438936	30438959	10	+	28162770	SKM1	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.062493535204711126	[126]	[214]	0	hSpCas9	negative selection	10696962
30450399	30450422	10	+	28162770	SKM1	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-1.1115083152169905	[21]	[17]	-7	hSpCas9	negative selection	10696963
30458096	30458119	10	+	28162770	SKM1	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	0.053907954253350376	[90]	[166]	0	hSpCas9	negative selection	10696964
30458181	30458204	10	-	28162770	SKM1	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	-0.21628063713405207	[68]	[104]	-2	hSpCas9	negative selection	10696965
30458203	30458226	10	-	28162770	SKM1	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	0.45363274459142167	[18]	[45]	4	hSpCas9	negative selection	10696966
30459440	30459463	10	-	28162770	SKM1	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.17799830197799427	[107]	[215]	1	hSpCas9	negative selection	10696967
30439132	30439155	10	+	28162770	SKM1	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.7629608026991508	[114]	[344]	7	hSpCas9	negative selection	10696968
30451723	30451746	10	+	28162770	SKM1	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.5930358012568382	[8]	[23]	6	hSpCas9	negative selection	10696969
30459414	30459437	10	-	28162770	SKM1	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.18425729244967703	[114]	[230]	1	hSpCas9	negative selection	10696970
30459458	30459481	10	+	28162770	SKM1	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	-0.19195130777231129	[41]	[64]	-2	hSpCas9	negative selection	10696971
30438936	30438959	10	+	28162770	PL21	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.26108751780959116	[401]	[145]	-2	hSpCas9	negative selection	10866328
30450399	30450422	10	+	28162770	PL21	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-2.1217884803980422	[59]	[5]	-8	hSpCas9	negative selection	10866329
30458096	30458119	10	+	28162770	PL21	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	-0.015589076566116966	[287]	[123]	0	hSpCas9	negative selection	10866330
30458181	30458204	10	-	28162770	PL21	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	-0.006904842513691785	[186]	[80]	0	hSpCas9	negative selection	10866331
30458203	30458226	10	-	28162770	PL21	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	-0.16909419517639912	[92]	[35]	-1	hSpCas9	negative selection	10866332
30459440	30459463	10	-	28162770	PL21	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.02657603598365954	[396]	[175]	0	hSpCas9	negative selection	10866333
30439132	30439155	10	+	28162770	PL21	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.013054061888824964	[295]	[129]	0	hSpCas9	negative selection	10866334
30451723	30451746	10	+	28162770	PL21	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	1.062636090739385	[32]	[29]	8	hSpCas9	negative selection	10866335
30459414	30459437	10	-	28162770	PL21	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.7001269861878843	[337]	[238]	6	hSpCas9	negative selection	10866336
30459458	30459481	10	+	28162770	PL21	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	1.7851021152104765	[113]	[170]	9	hSpCas9	negative selection	10866337
30438936	30438959	10	+	28162770	P31FUJ	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.2424108098938641	[404]	[562]	2	hSpCas9	negative selection	11035694
30450399	30450422	10	+	28162770	P31FUJ	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-0.5547302993017409	[49]	[39]	-5	hSpCas9	negative selection	11035695
30458096	30458119	10	+	28162770	P31FUJ	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	0.6465524415057605	[267]	[492]	7	hSpCas9	negative selection	11035696
30458181	30458204	10	-	28162770	P31FUJ	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	0.7019517709701832	[146]	[280]	7	hSpCas9	negative selection	11035697
30458203	30458226	10	-	28162770	P31FUJ	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	0.21650519694921155	[51]	[70]	2	hSpCas9	negative selection	11035698
30459440	30459463	10	-	28162770	P31FUJ	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	1.0119767917121472	[337]	[800]	9	hSpCas9	negative selection	11035699
30439132	30439155	10	+	28162770	P31FUJ	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.8896974508351969	[535]	[1166]	8	hSpCas9	negative selection	11035700
30451723	30451746	10	+	28162770	P31FUJ	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.15052643513712693	[45]	[59]	1	hSpCas9	negative selection	11035701
30459414	30459437	10	-	28162770	P31FUJ	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	-0.40002082283437157	[465]	[414]	-4	hSpCas9	negative selection	11035702
30459458	30459481	10	+	28162770	P31FUJ	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	0.7221099060570835	[194]	[377]	8	hSpCas9	negative selection	11035703
30438936	30438959	10	+	28162770	OCIAML5	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	1.109927106556258	[124]	[486]	8	hSpCas9	negative selection	11205060
30450399	30450422	10	+	28162770	OCIAML5	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	0.44071517836384877	[39]	[97]	4	hSpCas9	negative selection	11205061
30458096	30458119	10	+	28162770	OCIAML5	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	0.49129290455487634	[146]	[372]	4	hSpCas9	negative selection	11205062
30458181	30458204	10	-	28162770	OCIAML5	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	0.2340900728857176	[64]	[137]	2	hSpCas9	negative selection	11205063
30458203	30458226	10	-	28162770	OCIAML5	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	0.944946406972148	[39]	[138]	7	hSpCas9	negative selection	11205064
30459440	30459463	10	-	28162770	OCIAML5	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.179503508136873	[225]	[461]	1	hSpCas9	negative selection	11205065
30439132	30439155	10	+	28162770	OCIAML5	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.6178194054104669	[299]	[830]	5	hSpCas9	negative selection	11205066
30451723	30451746	10	+	28162770	OCIAML5	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	-0.5799870254271964	[52]	[63]	-4	hSpCas9	negative selection	11205067
30459414	30459437	10	-	28162770	OCIAML5	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.47595068909912985	[330]	[830]	4	hSpCas9	negative selection	11205068
30459458	30459481	10	+	28162770	OCIAML5	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	-0.6876797529631146	[115]	[129]	-4	hSpCas9	negative selection	11205069
30438936	30438959	10	+	28162770	EOL1	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.8149737657613205	[751]	[696]	7	hSpCas9	negative selection	11374426
30450399	30450422	10	+	28162770	EOL1	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-0.31830875232562894	[70]	[29]	-2	hSpCas9	negative selection	11374427
30458096	30458119	10	+	28162770	EOL1	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	0.5115551982767153	[469]	[352]	4	hSpCas9	negative selection	11374428
30458181	30458204	10	-	28162770	EOL1	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	0.2233533084261504	[238]	[146]	2	hSpCas9	negative selection	11374429
30458203	30458226	10	-	28162770	EOL1	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	1.0826956052364933	[163]	[182]	8	hSpCas9	negative selection	11374430
30459440	30459463	10	-	28162770	EOL1	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.3884948713303247	[666]	[459]	3	hSpCas9	negative selection	11374431
30439132	30439155	10	+	28162770	EOL1	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	-0.3390405582634944	[520]	[216]	-3	hSpCas9	negative selection	11374432
30451723	30451746	10	+	28162770	EOL1	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	1.9620224769891974	[37]	[77]	9	hSpCas9	negative selection	11374433
30459414	30459437	10	-	28162770	EOL1	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	-0.36592289179523046	[498]	[203]	-3	hSpCas9	negative selection	11374434
30459458	30459481	10	+	28162770	EOL1	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	-0.22229361675873655	[216]	[97]	-2	hSpCas9	negative selection	11374435
30438936	30438959	10	+	28162770	MOLM13	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.9384932499306315	[572]	[793]	7	hSpCas9	negative selection	11543792
30450399	30450422	10	+	28162770	MOLM13	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	0.6649262286041326	[81]	[93]	5	hSpCas9	negative selection	11543793
30458096	30458119	10	+	28162770	MOLM13	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	0.7028862430145122	[406]	[478]	5	hSpCas9	negative selection	11543794
30458181	30458204	10	-	28162770	MOLM13	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	-0.02114869917804177	[239]	[170]	0	hSpCas9	negative selection	11543795
30458203	30458226	10	-	28162770	MOLM13	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	0.34815013727048305	[112]	[103]	2	hSpCas9	negative selection	11543796
30459440	30459463	10	-	28162770	MOLM13	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.9283373405133691	[515]	[709]	7	hSpCas9	negative selection	11543797
30439132	30439155	10	+	28162770	MOLM13	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.8656128269741454	[481]	[634]	6	hSpCas9	negative selection	11543798
30451723	30451746	10	+	28162770	MOLM13	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	-0.7165351895928485	[49]	[21]	-4	hSpCas9	negative selection	11543799
30459414	30459437	10	-	28162770	MOLM13	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.2630258457758785	[558]	[484]	2	hSpCas9	negative selection	11543800
30459458	30459481	10	+	28162770	MOLM13	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	-1.1170731191765775	[266]	[88]	-5	hSpCas9	negative selection	11543801
30438936	30438959	10	+	28162770	HEL	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.8178255385584483	[526]	[594]	7	hSpCas9	negative selection	11713158
30450399	30450422	10	+	28162770	HEL	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-1.6051886814432286	[37]	[7]	-7	hSpCas9	negative selection	11713159
30458096	30458119	10	+	28162770	HEL	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	-0.23411293722677817	[403]	[219]	-2	hSpCas9	negative selection	11713160
30458181	30458204	10	-	28162770	HEL	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	1.265037483994486	[177]	[273]	9	hSpCas9	negative selection	11713161
30458203	30458226	10	-	28162770	HEL	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	0.8853091352744352	[70]	[83]	7	hSpCas9	negative selection	11713162
30459440	30459463	10	-	28162770	HEL	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.007444655729056171	[524]	[337]	0	hSpCas9	negative selection	11713163
30439132	30439155	10	+	28162770	HEL	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	-0.09326142586961894	[497]	[298]	0	hSpCas9	negative selection	11713164
30451723	30451746	10	+	28162770	HEL	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	-1.8426879951698845	[27]	[4]	-7	hSpCas9	negative selection	11713165
30459414	30459437	10	-	28162770	HEL	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.3390078447973346	[452]	[366]	3	hSpCas9	negative selection	11713166
30459458	30459481	10	+	28162770	HEL	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	0.2635858684200446	[224]	[172]	2	hSpCas9	negative selection	11713167
30438936	30438959	10	+	28162770	MV411	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.02208271559046593	[324]	[277]	0	hSpCas9	negative selection	11882524
30450399	30450422	10	+	28162770	MV411	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-1.9347657804379736	[58]	[12]	-8	hSpCas9	negative selection	11882525
30458096	30458119	10	+	28162770	MV411	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	-0.21424067361485727	[240]	[174]	-2	hSpCas9	negative selection	11882526
30458181	30458204	10	-	28162770	MV411	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	0.39576029773987653	[156]	[173]	3	hSpCas9	negative selection	11882527
30458203	30458226	10	-	28162770	MV411	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	0.1405223468662632	[83]	[77]	1	hSpCas9	negative selection	11882528
30459440	30459463	10	-	28162770	MV411	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.12593076919499469	[363]	[280]	-1	hSpCas9	negative selection	11882529
30439132	30439155	10	+	28162770	MV411	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.14683360984436944	[385]	[359]	1	hSpCas9	negative selection	11882530
30451723	30451746	10	+	28162770	MV411	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	1.0839388184998962	[41]	[74]	8	hSpCas9	negative selection	11882531
30459414	30459437	10	-	28162770	MV411	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.31740010895034276	[321]	[337]	3	hSpCas9	negative selection	11882532
30459458	30459481	10	+	28162770	MV411	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	-0.06119372149112928	[134]	[108]	0	hSpCas9	negative selection	11882533
30438936	30438959	10	+	28162770	MONOMAC1	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.20182190962493052	[301]	[300]	-2	hSpCas9	negative selection	12051890
30450399	30450422	10	+	28162770	MONOMAC1	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-1.0271118456172414	[31]	[17]	-7	hSpCas9	negative selection	12051891
30458096	30458119	10	+	28162770	MONOMAC1	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	-0.3145304100779943	[178]	[164]	-3	hSpCas9	negative selection	12051892
30458181	30458204	10	-	28162770	MONOMAC1	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	0.466679765076014	[100]	[159]	4	hSpCas9	negative selection	12051893
30458203	30458226	10	-	28162770	MONOMAC1	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	-1.675084143864198	[38]	[13]	-8	hSpCas9	negative selection	12051894
30459440	30459463	10	-	28162770	MONOMAC1	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.04994515348887418	[240]	[285]	0	hSpCas9	negative selection	12051895
30439132	30439155	10	+	28162770	MONOMAC1	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	-0.15202711214198827	[283]	[292]	-1	hSpCas9	negative selection	12051896
30451723	30451746	10	+	28162770	MONOMAC1	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	0.6103180749980504	[19]	[34]	6	hSpCas9	negative selection	12051897
30459414	30459437	10	-	28162770	MONOMAC1	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.1717922227968368	[229]	[296]	1	hSpCas9	negative selection	12051898
30459458	30459481	10	+	28162770	MONOMAC1	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	-0.4976963251932649	[100]	[81]	-4	hSpCas9	negative selection	12051899
30438936	30438959	10	+	28162770	OCIAML2	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	0.7403419005068252	[76]	[712]	7	hSpCas9	negative selection	12221256
30450399	30450422	10	+	28162770	OCIAML2	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	-0.36629316542742574	[9]	[42]	-3	hSpCas9	negative selection	12221257
30458096	30458119	10	+	28162770	OCIAML2	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	-0.0772223419348601	[62]	[330]	0	hSpCas9	negative selection	12221258
30458181	30458204	10	-	28162770	OCIAML2	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	-0.16806705522172996	[29]	[147]	-1	hSpCas9	negative selection	12221259
30458203	30458226	10	-	28162770	OCIAML2	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	0.28739738445187457	[16]	[114]	2	hSpCas9	negative selection	12221260
30459440	30459463	10	-	28162770	OCIAML2	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	0.4301605708299394	[78]	[589]	4	hSpCas9	negative selection	12221261
30439132	30439155	10	+	28162770	OCIAML2	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	1.006056823493231	[67]	[756]	8	hSpCas9	negative selection	12221262
30451723	30451746	10	+	28162770	OCIAML2	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	1.0212232710875133	[3]	[44]	8	hSpCas9	negative selection	12221263
30459414	30459437	10	-	28162770	OCIAML2	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.08810113390581531	[73]	[435]	0	hSpCas9	negative selection	12221264
30459458	30459481	10	+	28162770	OCIAML2	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	0.6992951762001511	[20]	[188]	6	hSpCas9	negative selection	12221265
30438936	30438959	10	+	28162770	OCIAML3	viability	GTAATGGAGTACATGAGCACTGG	MAP3K8	ENSG00000107968	-0.012866850555415255	[125]	[376]	0	hSpCas9	negative selection	12390622
30450399	30450422	10	+	28162770	OCIAML3	viability	CTGGAGAAACTGGAGAGCTGTGG	MAP3K8	ENSG00000107968	0.014801602351360632	[19]	[60]	0	hSpCas9	negative selection	12390623
30458096	30458119	10	+	28162770	OCIAML3	viability	CCAGAGGTCATCCTGTGCAGGGG	MAP3K8	ENSG00000107968	0.36946648365072265	[79]	[311]	3	hSpCas9	negative selection	12390624
30458181	30458204	10	-	28162770	OCIAML3	viability	GTAGCGCTTCACCCAGGGTGGGG	MAP3K8	ENSG00000107968	0.34306110394938	[40]	[156]	3	hSpCas9	negative selection	12390625
30458203	30458226	10	-	28162770	OCIAML3	viability	AGGAGGGATAGGCTGAGCGAGGG	MAP3K8	ENSG00000107968	-0.7639326417664754	[17]	[31]	-5	hSpCas9	negative selection	12390626
30459440	30459463	10	-	28162770	OCIAML3	viability	GCAGCCTCTTGCGCTCCAAGAGG	MAP3K8	ENSG00000107968	-0.24741749120253165	[115]	[294]	-2	hSpCas9	negative selection	12390627
30439132	30439155	10	+	28162770	OCIAML3	viability	TTAGTGGCCAAGAGGTACCATGG	MAP3K8	ENSG00000107968	0.2897993421713141	[125]	[464]	2	hSpCas9	negative selection	12390628
30451723	30451746	10	+	28162770	OCIAML3	viability	TAAGGACCTCCGAGGAACAGAGG	MAP3K8	ENSG00000107968	-0.4988504072838231	[21]	[46]	-4	hSpCas9	negative selection	12390629
30459414	30459437	10	-	28162770	OCIAML3	viability	GAGTCCAGACTCTGACAGCGTGG	MAP3K8	ENSG00000107968	0.4242777127035865	[97]	[396]	4	hSpCas9	negative selection	12390630
30459458	30459481	10	+	28162770	OCIAML3	viability	GCTGCTGAGTAGGAAGGAGCTGG	MAP3K8	ENSG00000107968	0.440262261760583	[51]	[212]	4	hSpCas9	negative selection	12390631