Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5594
• Symbol:MAPK1
• Description:mitogen-activated protein kinase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/MAPK1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
21805844	21805867	22	+	26472758	Jiyoye	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-0.2968397908590461	[302]	[185]	-2	hSpCas9	negative selection	96208
21867377	21867400	22	-	26472758	Jiyoye	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	-4.914752713381489	[39]	[0]	-9	hSpCas9	negative selection	96209
21867431	21867454	22	-	26472758	Jiyoye	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	1.642391843199905	[47]	[112]	8	hSpCas9	negative selection	96210
21807756	21807779	22	-	26472758	Jiyoye	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	0.5219957835077315	[168]	[182]	4	hSpCas9	negative selection	96211
21772914	21772937	22	-	26472758	Jiyoye	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	0.8652816026766031	[98]	[135]	6	hSpCas9	negative selection	96212
21805873	21805896	22	+	26472758	Jiyoye	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	0.308771677444879	[272]	[254]	2	hSpCas9	negative selection	96213
21805862	21805885	22	+	26472758	Jiyoye	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-1.5821773742946181	[134]	[33]	-7	hSpCas9	negative selection	96214
21788682	21788705	22	+	26472758	Jiyoye	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-0.30064386700081613	[146]	[89]	-2	hSpCas9	negative selection	96215
21772891	21772914	22	+	26472758	Jiyoye	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	5.616628747134823	[0]	[36]	9	hSpCas9	negative selection	96216
21772872	21772895	22	-	26472758	Jiyoye	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	0.3270050328218903	[36]	[34]	2	hSpCas9	negative selection	96217
21805844	21805867	22	+	26472758	KBM7	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-0.014528638652803294	[798,630]	[359,303]	0	hSpCas9	negative selection	287326
21867377	21867400	22	-	26472758	KBM7	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	-1.9315006105835266	[29,47]	[5,3]	-8	hSpCas9	negative selection	287327
21867431	21867454	22	-	26472758	KBM7	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	0.04499774822770913	[404,311]	[182,162]	0	hSpCas9	negative selection	287328
21807756	21807779	22	-	26472758	KBM7	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	-1.0433956496619878	[583,439]	[130,101]	-7	hSpCas9	negative selection	287329
21772914	21772937	22	-	26472758	KBM7	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-0.48142882765966927	[840,529]	[176,270]	-4	hSpCas9	negative selection	287330
21805873	21805896	22	+	26472758	KBM7	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-0.6232789948541861	[1156,690]	[348,210]	-5	hSpCas9	negative selection	287331
21805862	21805885	22	+	26472758	KBM7	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-0.3531311701959978	[414,395]	[165,134]	-3	hSpCas9	negative selection	287332
21788682	21788705	22	+	26472758	KBM7	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	0.6399831660179491	[385,528]	[413,277]	7	hSpCas9	negative selection	287333
21772891	21772914	22	+	26472758	KBM7	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	-1.8631703196733722	[110,197]	[17,22]	-8	hSpCas9	negative selection	287334
21772872	21772895	22	-	26472758	KBM7	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-1.3558070119190635	[312,299]	[94,21]	-7	hSpCas9	negative selection	287335
21805844	21805867	22	+	26472758	Raji	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	0.8668665661012332	[266]	[112]	7	hSpCas9	negative selection	478444
21867377	21867400	22	-	26472758	Raji	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	0.39117650137419036	[22]	[6]	4	hSpCas9	negative selection	478445
21867431	21867454	22	-	26472758	Raji	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	0.9080747271501927	[123]	[53]	8	hSpCas9	negative selection	478446
21807756	21807779	22	-	26472758	Raji	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	0.10231254582617766	[284]	[70]	0	hSpCas9	negative selection	478447
21772914	21772937	22	-	26472758	Raji	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-1.0890136774299042	[274]	[29]	-7	hSpCas9	negative selection	478448
21805873	21805896	22	+	26472758	Raji	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-0.9800793058767401	[492]	[57]	-6	hSpCas9	negative selection	478449
21805862	21805885	22	+	26472758	Raji	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-1.2082582966663318	[228]	[22]	-7	hSpCas9	negative selection	478450
21788682	21788705	22	+	26472758	Raji	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-0.6803958483472438	[365]	[52]	-5	hSpCas9	negative selection	478451
21772891	21772914	22	+	26472758	Raji	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	-0.6722263962011006	[102]	[14]	-5	hSpCas9	negative selection	478452
21772872	21772895	22	-	26472758	Raji	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-0.5771146388984711	[89]	[13]	-4	hSpCas9	negative selection	478453
21805844	21805867	22	+	26472758	K562	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-2.9443653010271813	[692]	[75]	-8	hSpCas9	negative selection	669562
21867377	21867400	22	-	26472758	K562	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	-2.3101701240111905	[46]	[7]	-8	hSpCas9	negative selection	669563
21867431	21867454	22	-	26472758	K562	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	-3.683688353851768	[273]	[17]	-9	hSpCas9	negative selection	669564
21807756	21807779	22	-	26472758	K562	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	-4.359207617319745	[388]	[15]	-9	hSpCas9	negative selection	669565
21772914	21772937	22	-	26472758	K562	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-5.770531613799525	[581]	[8]	-9	hSpCas9	negative selection	669566
21805873	21805896	22	+	26472758	K562	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-5.097973469780631	[851]	[20]	-9	hSpCas9	negative selection	669567
21805862	21805885	22	+	26472758	K562	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-7.082010759455856	[320]	[1]	-9	hSpCas9	negative selection	669568
21788682	21788705	22	+	26472758	K562	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-3.152098683641599	[515]	[48]	-8	hSpCas9	negative selection	669569
21772891	21772914	22	+	26472758	K562	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	-5.130620703680478	[82]	[1]	-9	hSpCas9	negative selection	669570
21772872	21772895	22	-	26472758	K562	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-6.993986011658631	[150]	[0]	-9	hSpCas9	negative selection	669571
21769297	21769320	22	+	26627737	DLD1	viability	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-0.041275352212338134	[820]	[342,291,132]	0	hSpCas9	negative selection	816917
21799092	21799115	22	+	26627737	DLD1	viability	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	-0.037870598600204586	[845]	[234,316,227]	0	hSpCas9	negative selection	816918
21805858	21805881	22	+	26627737	DLD1	viability	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-1.8419214868331477	[984]	[40,110,103]	-8	hSpCas9	negative selection	816919
21807772	21807795	22	+	26627737	DLD1	viability	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	-1.006499358292454	[949]	[188,60,183]	-7	hSpCas9	negative selection	816920
21867341	21867364	22	-	26627737	DLD1	viability	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.019521343908529998	[431]	[217,144,49]	0	hSpCas9	negative selection	816921
21867352	21867375	22	+	26627737	DLD1	viability	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-0.5573572576462025	[761]	[73,243,169]	-5	hSpCas9	negative selection	816922
21769297	21769320	22	+	26627737	GBM cells	viability after 5 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-0.5700624315039621	[435]	[167,146]	-7	hSpCas9	negative selection	899232
21799092	21799115	22	+	26627737	GBM cells	viability after 5 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.26786214372100414	[325]	[236,183]	4	hSpCas9	negative selection	899233
21805858	21805881	22	+	26627737	GBM cells	viability after 5 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	0.09231966734129804	[236]	[149,120]	1	hSpCas9	negative selection	899234
21807772	21807795	22	+	26627737	GBM cells	viability after 5 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.2662338725870622	[437]	[282,281]	4	hSpCas9	negative selection	899235
21867341	21867364	22	-	26627737	GBM cells	viability after 5 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.6752256565409342	[331]	[125,96]	-8	hSpCas9	negative selection	899236
21867352	21867375	22	+	26627737	GBM cells	viability after 5 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.7697065548823803	[425]	[74,58]	-9	hSpCas9	negative selection	899237
21769297	21769320	22	+	26627737	GBM cells	viability after 13 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-0.6492931633478751	[435]	[157,144]	-6	hSpCas9	negative selection	981547
21799092	21799115	22	+	26627737	GBM cells	viability after 13 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.45122965090725475	[325]	[323,174]	6	hSpCas9	negative selection	981548
21805858	21805881	22	+	26627737	GBM cells	viability after 13 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	0.17560815457263074	[236]	[131,155]	2	hSpCas9	negative selection	981549
21807772	21807795	22	+	26627737	GBM cells	viability after 13 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.4854515113565917	[437]	[308,351]	6	hSpCas9	negative selection	981550
21867341	21867364	22	-	26627737	GBM cells	viability after 13 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.8043774337660042	[331]	[122,86]	-7	hSpCas9	negative selection	981551
21867352	21867375	22	+	26627737	GBM cells	viability after 13 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.872803054853391	[425]	[77,50]	-9	hSpCas9	negative selection	981552
21769297	21769320	22	+	26627737	GBM cells	viability after 21 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-0.6025488062990199	[435]	[155,155]	-5	hSpCas9	negative selection	1063862
21799092	21799115	22	+	26627737	GBM cells	viability after 21 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.8603794983673212	[325]	[343,300]	8	hSpCas9	negative selection	1063863
21805858	21805881	22	+	26627737	GBM cells	viability after 21 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	0.1388645947346443	[236]	[158,125]	1	hSpCas9	negative selection	1063864
21807772	21807795	22	+	26627737	GBM cells	viability after 21 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.6354840255619537	[437]	[365,372]	6	hSpCas9	negative selection	1063865
21867341	21867364	22	-	26627737	GBM cells	viability after 21 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-2.522624075871029	[331]	[33,28]	-9	hSpCas9	negative selection	1063866
21867352	21867375	22	+	26627737	GBM cells	viability after 21 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-2.490682250912589	[425]	[36,44]	-9	hSpCas9	negative selection	1063867
21769297	21769320	22	+	26627737	RPE1	viability after 9 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	0.5277574001776575	[1006]	[364,569]	3	hSpCas9	negative selection	1146177
21799092	21799115	22	+	26627737	RPE1	viability after 9 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.39226876337236216	[513]	[122,324]	2	hSpCas9	negative selection	1146178
21805858	21805881	22	+	26627737	RPE1	viability after 9 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-0.01816312614206783	[1135]	[355,344]	0	hSpCas9	negative selection	1146179
21807772	21807795	22	+	26627737	RPE1	viability after 9 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	-0.7083354756041866	[1527]	[273,316]	-5	hSpCas9	negative selection	1146180
21867341	21867364	22	-	26627737	RPE1	viability after 9 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.8489561581698172	[406]	[108,384]	5	hSpCas9	negative selection	1146181
21867352	21867375	22	+	26627737	RPE1	viability after 9 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.2889502385563754	[2180]	[247,319]	-7	hSpCas9	negative selection	1146182
21769297	21769320	22	+	26627737	RPE1	viability after 12 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-0.05435966314556556	[1006]	[312,204]	0	hSpCas9	negative selection	1228492
21799092	21799115	22	+	26627737	RPE1	viability after 12 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.04371315177512969	[513]	[102,183]	0	hSpCas9	negative selection	1228493
21805858	21805881	22	+	26627737	RPE1	viability after 12 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-0.23301286675146277	[1135]	[265,252]	-1	hSpCas9	negative selection	1228494
21807772	21807795	22	+	26627737	RPE1	viability after 12 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	-0.9499014006955895	[1527]	[229,193]	-6	hSpCas9	negative selection	1228495
21867341	21867364	22	-	26627737	RPE1	viability after 12 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.09590978621755109	[406]	[112,90]	0	hSpCas9	negative selection	1228496
21867352	21867375	22	+	26627737	RPE1	viability after 12 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.4304545128276658	[2180]	[247,184]	-7	hSpCas9	negative selection	1228497
21769297	21769320	22	+	26627737	RPE1	viability after 15 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	0.09044232696496451	[1006]	[483,128]	0	hSpCas9	negative selection	1310807
21799092	21799115	22	+	26627737	RPE1	viability after 15 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.0028380099744145237	[513]	[78,209]	0	hSpCas9	negative selection	1310808
21805858	21805881	22	+	26627737	RPE1	viability after 15 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-0.4846526851499077	[1135]	[276,183]	-3	hSpCas9	negative selection	1310809
21807772	21807795	22	+	26627737	RPE1	viability after 15 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	-1.094417743727745	[1527]	[318,89]	-6	hSpCas9	negative selection	1310810
21867341	21867364	22	-	26627737	RPE1	viability after 15 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.13541074774451323	[406]	[86,121]	-1	hSpCas9	negative selection	1310811
21867352	21867375	22	+	26627737	RPE1	viability after 15 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.858156594400573	[2180]	[75,260]	-8	hSpCas9	negative selection	1310812
21769297	21769320	22	+	26627737	RPE1	viability after 18 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-0.6277196403720968	[1006]	[186,163]	-4	hSpCas9	negative selection	1393122
21799092	21799115	22	+	26627737	RPE1	viability after 18 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	-0.3660153922060706	[513]	[23,196]	-2	hSpCas9	negative selection	1393123
21805858	21805881	22	+	26627737	RPE1	viability after 18 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	0.027994490614400402	[1135]	[241,387]	0	hSpCas9	negative selection	1393124
21807772	21807795	22	+	26627737	RPE1	viability after 18 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	-2.5125273527322496	[1527]	[79,63]	-8	hSpCas9	negative selection	1393125
21867341	21867364	22	-	26627737	RPE1	viability after 18 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.22893306365566202	[406]	[76,183]	1	hSpCas9	negative selection	1393126
21867352	21867375	22	+	26627737	RPE1	viability after 18 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-2.148138627695707	[2180]	[111,154]	-8	hSpCas9	negative selection	1393127
21769297	21769320	22	+	26627737	HeLa	viability after 8 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-1.3748100779156833	[1233]	[331,173,146]	-8	hSpCas9	negative selection	1475437
21799092	21799115	22	+	26627737	HeLa	viability after 8 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	-0.3403905538772503	[604]	[295,121,223]	-3	hSpCas9	negative selection	1475438
21805858	21805881	22	+	26627737	HeLa	viability after 8 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	0.4448322576219746	[480]	[406,314,167]	4	hSpCas9	negative selection	1475439
21807772	21807795	22	+	26627737	HeLa	viability after 8 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.5541518936868354	[474]	[501,279,180]	5	hSpCas9	negative selection	1475440
21867341	21867364	22	-	26627737	HeLa	viability after 8 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.4972608617803106	[674]	[144,325,143]	-5	hSpCas9	negative selection	1475441
21867352	21867375	22	+	26627737	HeLa	viability after 8 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-0.2757309165177846	[996]	[410,440,242]	-3	hSpCas9	negative selection	1475442
21769297	21769320	22	+	26627737	HeLa	viability after 12 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-0.04507008384483324	[1233]	[577,496,409]	0	hSpCas9	negative selection	1557752
21799092	21799115	22	+	26627737	HeLa	viability after 12 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.5339802059474041	[604]	[215,463,390]	4	hSpCas9	negative selection	1557753
21805858	21805881	22	+	26627737	HeLa	viability after 12 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-0.2860100052598522	[480]	[122,303,45]	-3	hSpCas9	negative selection	1557754
21807772	21807795	22	+	26627737	HeLa	viability after 12 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.7606449713970947	[474]	[375,209,425]	6	hSpCas9	negative selection	1557755
21867341	21867364	22	-	26627737	HeLa	viability after 12 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.20480212359243344	[674]	[333,239,154]	-2	hSpCas9	negative selection	1557756
21867352	21867375	22	+	26627737	HeLa	viability after 12 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-0.568419784003889	[996]	[310,244,281]	-5	hSpCas9	negative selection	1557757
21769297	21769320	22	+	26627737	HeLa	viability after 15 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-0.8488923409881595	[1233]	[270,248,319]	-6	hSpCas9	negative selection	1640067
21799092	21799115	22	+	26627737	HeLa	viability after 15 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.5823640742899698	[604]	[352,330,426]	5	hSpCas9	negative selection	1640068
21805858	21805881	22	+	26627737	HeLa	viability after 15 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-0.08871262781436257	[480]	[132,260,156]	0	hSpCas9	negative selection	1640069
21807772	21807795	22	+	26627737	HeLa	viability after 15 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.21868555675087714	[474]	[214,140,326]	1	hSpCas9	negative selection	1640070
21867341	21867364	22	-	26627737	HeLa	viability after 15 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.2036028924269342	[674]	[312,113,291]	-2	hSpCas9	negative selection	1640071
21867352	21867375	22	+	26627737	HeLa	viability after 15 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-0.4217936746349029	[996]	[140,346,432]	-4	hSpCas9	negative selection	1640072
21769297	21769320	22	+	26627737	HeLa	viability after 18 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-0.8562902437898045	[1233]	[175,209,319]	-6	hSpCas9	negative selection	1722382
21799092	21799115	22	+	26627737	HeLa	viability after 18 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.612392597267325	[604]	[247,278,426]	5	hSpCas9	negative selection	1722383
21805858	21805881	22	+	26627737	HeLa	viability after 18 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-0.06684838556802988	[480]	[89,221,156]	0	hSpCas9	negative selection	1722384
21807772	21807795	22	+	26627737	HeLa	viability after 18 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.221124739207612	[474]	[139,122,326]	1	hSpCas9	negative selection	1722385
21867341	21867364	22	-	26627737	HeLa	viability after 18 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.3245584270394636	[674]	[176,88,291]	-3	hSpCas9	negative selection	1722386
21867352	21867375	22	+	26627737	HeLa	viability after 18 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-0.4288272654839568	[996]	[87,291,432]	-4	hSpCas9	negative selection	1722387
21769297	21769320	22	+	26627737	HCT116	viability after 6 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	1.413716482653419	[1113]	[434,483]	7	hSpCas9	negative selection	1804697
21799092	21799115	22	+	26627737	HCT116	viability after 6 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.08853274752547521	[610]	[105,99]	0	hSpCas9	negative selection	1804698
21805858	21805881	22	+	26627737	HCT116	viability after 6 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	0.17422914796022823	[643]	[159,88]	1	hSpCas9	negative selection	1804699
21807772	21807795	22	+	26627737	HCT116	viability after 6 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	-0.07753381842481433	[1047]	[159,153]	0	hSpCas9	negative selection	1804700
21867341	21867364	22	-	26627737	HCT116	viability after 6 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.23351721913446494	[802]	[179,130]	1	hSpCas9	negative selection	1804701
21867352	21867375	22	+	26627737	HCT116	viability after 6 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	1.292158552176832	[1204]	[713,325]	7	hSpCas9	negative selection	1804702
21769297	21769320	22	+	26627737	HCT116	viability after 8 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	0.21570476428210278	[360]	[334,222,137]	2	hSpCas9	negative selection	1887012
21799092	21799115	22	+	26627737	HCT116	viability after 8 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.6166158548529367	[329]	[329,282,224]	6	hSpCas9	negative selection	1887013
21805858	21805881	22	+	26627737	HCT116	viability after 8 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-0.5284927398416813	[676]	[308,227,239]	-6	hSpCas9	negative selection	1887014
21807772	21807795	22	+	26627737	HCT116	viability after 8 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.2087877162115791	[412]	[187,361,237]	2	hSpCas9	negative selection	1887015
21867341	21867364	22	-	26627737	HCT116	viability after 8 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.6019719693152525	[252]	[324,115,195]	6	hSpCas9	negative selection	1887016
21867352	21867375	22	+	26627737	HCT116	viability after 8 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.2208911067709651	[704]	[211,138,149]	-9	hSpCas9	negative selection	1887017
21769297	21769320	22	+	26627737	HCT116	viability after 9 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	0.6752947214680277	[1113]	[512,444]	5	hSpCas9	negative selection	1969327
21799092	21799115	22	+	26627737	HCT116	viability after 9 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.833987716890642	[610]	[425,183]	6	hSpCas9	negative selection	1969328
21805858	21805881	22	+	26627737	HCT116	viability after 9 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	0.27925384837849954	[643]	[411,47]	2	hSpCas9	negative selection	1969329
21807772	21807795	22	+	26627737	HCT116	viability after 9 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.2228443181429337	[1047]	[239,394]	1	hSpCas9	negative selection	1969330
21867341	21867364	22	-	26627737	HCT116	viability after 9 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.06610262457246852	[802]	[95,325]	0	hSpCas9	negative selection	1969331
21867352	21867375	22	+	26627737	HCT116	viability after 9 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-0.9661861162789611	[1204]	[138,184]	-6	hSpCas9	negative selection	1969332
21769297	21769320	22	+	26627737	HCT116	viability after 12 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	0.3479713178965586	[360]	[123,335,276]	3	hSpCas9	negative selection	2051642
21799092	21799115	22	+	26627737	HCT116	viability after 12 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.8386325559907142	[329]	[342,328,255]	7	hSpCas9	negative selection	2051643
21805858	21805881	22	+	26627737	HCT116	viability after 12 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-1.1498690378914496	[676]	[210,136,127]	-8	hSpCas9	negative selection	2051644
21807772	21807795	22	+	26627737	HCT116	viability after 12 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.48184024164716166	[412]	[302,330,275]	5	hSpCas9	negative selection	2051645
21867341	21867364	22	-	26627737	HCT116	viability after 12 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.24575845227498078	[252]	[174,139,155]	2	hSpCas9	negative selection	2051646
21867352	21867375	22	+	26627737	HCT116	viability after 12 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.6701873959564817	[704]	[37,110,206]	-9	hSpCas9	negative selection	2051647
21769297	21769320	22	+	26627737	HCT116	viability after 15 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-0.06372333004752379	[360]	[145,267,174]	0	hSpCas9	negative selection	2133957
21799092	21799115	22	+	26627737	HCT116	viability after 15 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.36118919546373457	[329]	[307,173,255]	3	hSpCas9	negative selection	2133958
21805858	21805881	22	+	26627737	HCT116	viability after 15 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-1.8143879600880521	[676]	[115,80,134]	-9	hSpCas9	negative selection	2133959
21807772	21807795	22	+	26627737	HCT116	viability after 15 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.4398773656090992	[412]	[259,400,296]	4	hSpCas9	negative selection	2133960
21867341	21867364	22	-	26627737	HCT116	viability after 15 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.10843585534488892	[252]	[168,193,108]	1	hSpCas9	negative selection	2133961
21867352	21867375	22	+	26627737	HCT116	viability after 15 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.6654329325166741	[704]	[132,75,173]	-9	hSpCas9	negative selection	2133962
21769297	21769320	22	+	26627737	HCT116	viability after 18 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	-0.23725145291498412	[360]	[236,95,112]	-2	hSpCas9	negative selection	2216272
21799092	21799115	22	+	26627737	HCT116	viability after 18 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	1.3416058298361588	[329]	[460,397,351]	8	hSpCas9	negative selection	2216273
21805858	21805881	22	+	26627737	HCT116	viability after 18 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-1.510975610769129	[676]	[161,39,148]	-8	hSpCas9	negative selection	2216274
21807772	21807795	22	+	26627737	HCT116	viability after 18 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.4565671895523068	[412]	[279,279,260]	4	hSpCas9	negative selection	2216275
21867341	21867364	22	-	26627737	HCT116	viability after 18 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-1.5101792043358524	[252]	[44,31,52]	-8	hSpCas9	negative selection	2216276
21867352	21867375	22	+	26627737	HCT116	viability after 18 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.9862524016266292	[704]	[28,32,204]	-9	hSpCas9	negative selection	2216277
21867321	21867344	22	-	24336569	HL60	viability	AGGGCGCCTACGGCATGGTGTGG	MAPK1	ENSG00000100030	-1.52293500776052	[917]	[675]	-8	hSpCas9	negative selection	2276050
21867326	21867349	22	-	24336569	HL60	viability	CGGCGAGGGCGCCTACGGCATGG	MAPK1	ENSG00000100030	-1.2162407799633501	[739]	[673]	-8	hSpCas9	negative selection	2276051
21867331	21867354	22	-	24336569	HL60	viability	TACATCGGCGAGGGCGCCTACGG	MAPK1	ENSG00000100030	-1.9235516168885636	[535]	[298]	-9	hSpCas9	negative selection	2276052
21867338	21867361	22	+	24336569	HL60	viability	CGCCCTCGCCGATGTACGAGAGG	MAPK1	ENSG00000100030	0.6224515274704149	[286]	[934]	5	hSpCas9	negative selection	2276053
21867346	21867369	22	-	24336569	HL60	viability	TACACCAACCTCTCGTACATCGG	MAPK1	ENSG00000100030	0.5245670061159522	[996]	[3034]	4	hSpCas9	negative selection	2276054
21867352	21867375	22	+	24336569	HL60	viability	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.3931238600624312	[524]	[422]	-8	hSpCas9	negative selection	2276055
21867376	21867399	22	-	24336569	HL60	viability	CGCGGGCAGGTGTTCGACGTGGG	MAPK1	ENSG00000100030	-0.34838542854684984	[668]	[1111]	-3	hSpCas9	negative selection	2276056
21867388	21867411	22	+	24336569	HL60	viability	ACCTGCCCGCGGACCATCTCCGG	MAPK1	ENSG00000100030	-0.9262160113469421	[976]	[1087]	-7	hSpCas9	negative selection	2276057
21867393	21867416	22	-	24336569	HL60	viability	CGGGCCCGGAGATGGTCCGCGGG	MAPK1	ENSG00000100030	0.3093839330828766	[420]	[1103]	3	hSpCas9	negative selection	2276058
21867428	21867451	22	-	24336569	HL60	viability	GGCAGCCAACATGGCGGCGGCGG	MAPK1	ENSG00000100030	-0.05115426647163755	[470]	[961]	0	hSpCas9	negative selection	2276059
21867321	21867344	22	-	24336569	KBM7	viability	AGGGCGCCTACGGCATGGTGTGG	MAPK1	ENSG00000100030	-1.1353261626993012	[1166]	[1448]	-7	hSpCas9	negative selection	2343227
21867326	21867349	22	-	24336569	KBM7	viability	CGGCGAGGGCGCCTACGGCATGG	MAPK1	ENSG00000100030	-2.1274593680869573	[478]	[298]	-8	hSpCas9	negative selection	2343228
21867331	21867354	22	-	24336569	KBM7	viability	TACATCGGCGAGGGCGCCTACGG	MAPK1	ENSG00000100030	-0.6820444501859056	[299]	[509]	-5	hSpCas9	negative selection	2343229
21867338	21867361	22	+	24336569	KBM7	viability	CGCCCTCGCCGATGTACGAGAGG	MAPK1	ENSG00000100030	1.6673643811235637	[103]	[900]	9	hSpCas9	negative selection	2343230
21867346	21867369	22	-	24336569	KBM7	viability	TACACCAACCTCTCGTACATCGG	MAPK1	ENSG00000100030	-0.16283770361569583	[895]	[2182]	-1	hSpCas9	negative selection	2343231
21867352	21867375	22	+	24336569	KBM7	viability	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.207408899066826	[529]	[625]	-7	hSpCas9	negative selection	2343232
21867376	21867399	22	-	24336569	KBM7	viability	CGCGGGCAGGTGTTCGACGTGGG	MAPK1	ENSG00000100030	-1.6346647491493775	[961]	[844]	-8	hSpCas9	negative selection	2343233
21867388	21867411	22	+	24336569	KBM7	viability	ACCTGCCCGCGGACCATCTCCGG	MAPK1	ENSG00000100030	-0.6053551153250787	[472]	[847]	-5	hSpCas9	negative selection	2343234
21867393	21867416	22	-	24336569	KBM7	viability	CGGGCCCGGAGATGGTCCGCGGG	MAPK1	ENSG00000100030	-0.7338833817055236	[299]	[491]	-5	hSpCas9	negative selection	2343235
21867428	21867451	22	-	24336569	KBM7	viability	GGCAGCCAACATGGCGGCGGCGG	MAPK1	ENSG00000100030	0.09371283251529705	[435]	[1268]	0	hSpCas9	negative selection	2343236
21782724	21782747	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGAGGACTGCTTGAGCCCGGG	MAPK1	ENSG00000100030	0.7107825170273987	[226,48]	[71,23]	3	dCas9-VP64	positive selection	2383399
21808777	21808800	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAAGCTGGGG	MAPK1	ENSG00000100030	4.479776146187553	[3,10]	[5,71]	9	dCas9-VP64	positive selection	2414960
21817750	21817773	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCAAGAGGATCACTTGAGCCAGG	MAPK1	ENSG00000100030	0.169734143386715	[57,44]	[12,10]	0	dCas9-VP64	positive selection	2416867
21820858	21820881	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCACTGCACTCCAACCTTGG	MAPK1	ENSG00000100030	2.1497742914119513	[2,11]	[5,8]	7	dCas9-VP64	positive selection	2439386
21840327	21840350	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCTGGTCTCAAACTCCTAGG	MAPK1	ENSG00000100030	1.754298476960665	[131,229]	[162,104]	6	dCas9-VP64	positive selection	2469980
21838311	21838334	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCACCACTGCACTCCAGCCCGG	MAPK1	ENSG00000100030	3.0347564003538725	[8,6]	[27,0]	8	dCas9-VP64	positive selection	2470816
21782724	21782747	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGAGGACTGCTTGAGCCCGGG	MAPK1	ENSG00000100030	0.4123872135065094	[127,354]	[119,88]	3	dCas9-VP64	positive selection	2478654
21808777	21808800	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAAGCTGGGG	MAPK1	ENSG00000100030	1.4055177615841226	[19,51]	[4,54]	7	dCas9-VP64	positive selection	2510215
21817750	21817773	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCAAGAGGATCACTTGAGCCAGG	MAPK1	ENSG00000100030	-0.04478500742304492	[42,58]	[7,21]	0	dCas9-VP64	positive selection	2512122
21820858	21820881	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCACTGCACTCCAACCTTGG	MAPK1	ENSG00000100030	0.6658120072320489	[88,38]	[30,34]	5	dCas9-VP64	positive selection	2534641
21840327	21840350	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCTGGTCTCAAACTCCTAGG	MAPK1	ENSG00000100030	0.3544513964898359	[322,573]	[129,237]	3	dCas9-VP64	positive selection	2565235
21838311	21838334	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCACCACTGCACTCCAGCCCGG	MAPK1	ENSG00000100030	0.038175304513698105	[60,77]	[26,18]	0	dCas9-VP64	positive selection	2566071
21867352	21867375	22	+	27260157	DLD1	viability	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-0.937894633130764	[]	[]	-6	hSpCas9	negative selection	2573853
21807761	21807784	22	+	27260157	DLD1	viability	GGGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-1.25439873735973	[]	[]	-7	hSpCas9	negative selection	2576296
21867321	21867344	22	-	27260157	DLD1	viability	AGGGCGCCTACGGCATGGTGTGG	MAPK1	ENSG00000100030	-1.42396943574017	[]	[]	-8	hSpCas9	negative selection	2576323
21867341	21867364	22	-	27260157	DLD1	viability	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.167731958189403	[]	[]	3	hSpCas9	negative selection	2580136
21867377	21867400	22	+	27260157	DLD1	viability	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	-0.476832464204109	[]	[]	-4	hSpCas9	negative selection	2581101
21867376	21867399	22	-	27260157	DLD1	viability	CGCGGGCAGGTGTTCGACGTGGG	MAPK1	ENSG00000100030	-2.48795555033946	[]	[]	-9	hSpCas9	negative selection	2581169
21867338	21867361	22	+	27260157	DLD1	viability	CGCCCTCGCCGATGTACGAGAGG	MAPK1	ENSG00000100030	0.866816616567603	[]	[]	9	hSpCas9	negative selection	2581899
21805934	21805957	22	-	27260157	DLD1	viability	TTCTCTACCAGATCCTCAGAGGG	MAPK1	ENSG00000100030	-0.135782081057738	[]	[]	-1	hSpCas9	negative selection	2582597
21807771	21807794	22	+	27260157	DLD1	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	0.228636345240212	[]	[]	3	hSpCas9	negative selection	2583327
21867430	21867453	22	+	27260157	DLD1	viability	GCCGCCGCCATGTTGGCTGCCGG	MAPK1	ENSG00000100030	0.842855030577497	[]	[]	9	hSpCas9	negative selection	2587182
21807755	21807778	22	-	27260157	DLD1	viability	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	-0.200176155127312	[]	[]	-1	hSpCas9	negative selection	2604534
21867388	21867411	22	+	27260157	DLD1	viability	ACCTGCCCGCGGACCATCTCCGG	MAPK1	ENSG00000100030	0.218031862622479	[]	[]	3	hSpCas9	negative selection	2604903
21867393	21867416	22	-	27260157	DLD1	viability	CGGGCCCGGAGATGGTCCGCGGG	MAPK1	ENSG00000100030	-0.752984691270769	[]	[]	-5	hSpCas9	negative selection	2606801
21867326	21867349	22	-	27260157	DLD1	viability	CGGCGAGGGCGCCTACGGCATGG	MAPK1	ENSG00000100030	-1.13240981716436	[]	[]	-7	hSpCas9	negative selection	2608745
21867375	21867398	22	-	27260157	DLD1	viability	GCGGGCAGGTGTTCGACGTGGGG	MAPK1	ENSG00000100030	-0.455972620577914	[]	[]	-4	hSpCas9	negative selection	2613435
21867428	21867451	22	-	27260157	DLD1	viability	GGCAGCCAACATGGCGGCGGCGG	MAPK1	ENSG00000100030	-1.04901378063208	[]	[]	-7	hSpCas9	negative selection	2614941
21805960	21805983	22	+	27260157	DLD1	viability	AGCAGATATGGTCATTGCTGAGG	MAPK1	ENSG00000100030	-1.17306912717243	[]	[]	-7	hSpCas9	negative selection	2616311
21867331	21867354	22	-	27260157	DLD1	viability	TACATCGGCGAGGGCGCCTACGG	MAPK1	ENSG00000100030	-1.173752429342	[]	[]	-7	hSpCas9	negative selection	2616597
21867346	21867369	22	-	27260157	DLD1	viability	TACACCAACCTCTCGTACATCGG	MAPK1	ENSG00000100030	-0.955661994118584	[]	[]	-7	hSpCas9	negative selection	2642191
21807749	21807772	22	+	27260157	DLD1	viability	TTATCTCCCTCAGGGTTCTCTGG	MAPK1	ENSG00000100030	-0.151818341495263	[]	[]	-1	hSpCas9	negative selection	2649188
21867352	21867375	22	+	27260157	HT1080	viability	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-1.11137770841922	[]	[]	-8	hSpCas9	negative selection	2649983
21807761	21807784	22	+	27260157	HT1080	viability	GGGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-1.87325474614723	[]	[]	-9	hSpCas9	negative selection	2652426
21867321	21867344	22	-	27260157	HT1080	viability	AGGGCGCCTACGGCATGGTGTGG	MAPK1	ENSG00000100030	-2.4039623256727	[]	[]	-9	hSpCas9	negative selection	2652453
21867341	21867364	22	-	27260157	HT1080	viability	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.672565222802847	[]	[]	-8	hSpCas9	negative selection	2656266
21867377	21867400	22	+	27260157	HT1080	viability	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	-0.745374476526038	[]	[]	-8	hSpCas9	negative selection	2657231
21867376	21867399	22	-	27260157	HT1080	viability	CGCGGGCAGGTGTTCGACGTGGG	MAPK1	ENSG00000100030	-0.909900885729027	[]	[]	-8	hSpCas9	negative selection	2657299
21867338	21867361	22	+	27260157	HT1080	viability	CGCCCTCGCCGATGTACGAGAGG	MAPK1	ENSG00000100030	0.815469469407484	[]	[]	7	hSpCas9	negative selection	2658029
21805934	21805957	22	-	27260157	HT1080	viability	TTCTCTACCAGATCCTCAGAGGG	MAPK1	ENSG00000100030	-2.0168784487863	[]	[]	-9	hSpCas9	negative selection	2658727
21807771	21807794	22	+	27260157	HT1080	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-1.17584970776446	[]	[]	-8	hSpCas9	negative selection	2659457
21867430	21867453	22	+	27260157	HT1080	viability	GCCGCCGCCATGTTGGCTGCCGG	MAPK1	ENSG00000100030	2.25495230538758	[]	[]	9	hSpCas9	negative selection	2663312
21807755	21807778	22	-	27260157	HT1080	viability	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	-0.963882346186094	[]	[]	-8	hSpCas9	negative selection	2680664
21867388	21867411	22	+	27260157	HT1080	viability	ACCTGCCCGCGGACCATCTCCGG	MAPK1	ENSG00000100030	-0.107393552745302	[]	[]	0	hSpCas9	negative selection	2681033
21867393	21867416	22	-	27260157	HT1080	viability	CGGGCCCGGAGATGGTCCGCGGG	MAPK1	ENSG00000100030	-0.928882693659869	[]	[]	-8	hSpCas9	negative selection	2682931
21867326	21867349	22	-	27260157	HT1080	viability	CGGCGAGGGCGCCTACGGCATGG	MAPK1	ENSG00000100030	-1.21443928242017	[]	[]	-8	hSpCas9	negative selection	2684875
21867375	21867398	22	-	27260157	HT1080	viability	GCGGGCAGGTGTTCGACGTGGGG	MAPK1	ENSG00000100030	-0.490083085243087	[]	[]	-7	hSpCas9	negative selection	2689565
21867428	21867451	22	-	27260157	HT1080	viability	GGCAGCCAACATGGCGGCGGCGG	MAPK1	ENSG00000100030	-0.0811923349643821	[]	[]	0	hSpCas9	negative selection	2691071
21805960	21805983	22	+	27260157	HT1080	viability	AGCAGATATGGTCATTGCTGAGG	MAPK1	ENSG00000100030	-1.31997892982524	[]	[]	-9	hSpCas9	negative selection	2692441
21867331	21867354	22	-	27260157	HT1080	viability	TACATCGGCGAGGGCGCCTACGG	MAPK1	ENSG00000100030	-0.812170006693135	[]	[]	-8	hSpCas9	negative selection	2692727
21867346	21867369	22	-	27260157	HT1080	viability	TACACCAACCTCTCGTACATCGG	MAPK1	ENSG00000100030	-0.924770811427028	[]	[]	-8	hSpCas9	negative selection	2718321
21807749	21807772	22	+	27260157	HT1080	viability	TTATCTCCCTCAGGGTTCTCTGG	MAPK1	ENSG00000100030	-1.66469692446067	[]	[]	-9	hSpCas9	negative selection	2725318
21867352	21867375	22	+	27260157	MKN45	viability	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	0.863557982915423	[]	[]	8	hSpCas9	negative selection	2726113
21807761	21807784	22	+	27260157	MKN45	viability	GGGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-0.470499404578518	[]	[]	-6	hSpCas9	negative selection	2728556
21867321	21867344	22	-	27260157	MKN45	viability	AGGGCGCCTACGGCATGGTGTGG	MAPK1	ENSG00000100030	-1.54812248834821	[]	[]	-9	hSpCas9	negative selection	2728583
21867341	21867364	22	-	27260157	MKN45	viability	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.626399466100539	[]	[]	7	hSpCas9	negative selection	2732396
21867377	21867400	22	+	27260157	MKN45	viability	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	0.443549949022767	[]	[]	6	hSpCas9	negative selection	2733361
21867376	21867399	22	-	27260157	MKN45	viability	CGCGGGCAGGTGTTCGACGTGGG	MAPK1	ENSG00000100030	-0.397706098171152	[]	[]	-1	hSpCas9	negative selection	2733429
21867338	21867361	22	+	27260157	MKN45	viability	CGCCCTCGCCGATGTACGAGAGG	MAPK1	ENSG00000100030	1.02906302659429	[]	[]	8	hSpCas9	negative selection	2734159
21805934	21805957	22	-	27260157	MKN45	viability	TTCTCTACCAGATCCTCAGAGGG	MAPK1	ENSG00000100030	1.11955807736787	[]	[]	8	hSpCas9	negative selection	2734857
21807771	21807794	22	+	27260157	MKN45	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.621108615522586	[]	[]	-6	hSpCas9	negative selection	2735587
21867430	21867453	22	+	27260157	MKN45	viability	GCCGCCGCCATGTTGGCTGCCGG	MAPK1	ENSG00000100030	0.52853754911826	[]	[]	6	hSpCas9	negative selection	2739442
21807755	21807778	22	-	27260157	MKN45	viability	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	0.51076315101209	[]	[]	6	hSpCas9	negative selection	2756794
21867388	21867411	22	+	27260157	MKN45	viability	ACCTGCCCGCGGACCATCTCCGG	MAPK1	ENSG00000100030	1.65052285763125	[]	[]	9	hSpCas9	negative selection	2757163
21867393	21867416	22	-	27260157	MKN45	viability	CGGGCCCGGAGATGGTCCGCGGG	MAPK1	ENSG00000100030	0.253800077348854	[]	[]	5	hSpCas9	negative selection	2759061
21867326	21867349	22	-	27260157	MKN45	viability	CGGCGAGGGCGCCTACGGCATGG	MAPK1	ENSG00000100030	0.377149887536386	[]	[]	6	hSpCas9	negative selection	2761005
21867375	21867398	22	-	27260157	MKN45	viability	GCGGGCAGGTGTTCGACGTGGGG	MAPK1	ENSG00000100030	-0.749785154952911	[]	[]	-7	hSpCas9	negative selection	2765695
21867428	21867451	22	-	27260157	MKN45	viability	GGCAGCCAACATGGCGGCGGCGG	MAPK1	ENSG00000100030	0.380912294979371	[]	[]	6	hSpCas9	negative selection	2767201
21805960	21805983	22	+	27260157	MKN45	viability	AGCAGATATGGTCATTGCTGAGG	MAPK1	ENSG00000100030	-0.9220362477313	[]	[]	-7	hSpCas9	negative selection	2768571
21867331	21867354	22	-	27260157	MKN45	viability	TACATCGGCGAGGGCGCCTACGG	MAPK1	ENSG00000100030	-0.477768633808348	[]	[]	-6	hSpCas9	negative selection	2768857
21867346	21867369	22	-	27260157	MKN45	viability	TACACCAACCTCTCGTACATCGG	MAPK1	ENSG00000100030	0.0996783976121943	[]	[]	0	hSpCas9	negative selection	2794451
21807749	21807772	22	+	27260157	MKN45	viability	TTATCTCCCTCAGGGTTCTCTGG	MAPK1	ENSG00000100030	-0.483832674449639	[]	[]	-6	hSpCas9	negative selection	2801448
21867352	21867375	22	+	27260157	RKO	viability	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	0.313669767135844	[]	[]	1	hSpCas9	negative selection	2802243
21807761	21807784	22	+	27260157	RKO	viability	GGGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-0.454986163662236	[]	[]	-6	hSpCas9	negative selection	2804686
21867321	21867344	22	-	27260157	RKO	viability	AGGGCGCCTACGGCATGGTGTGG	MAPK1	ENSG00000100030	-0.198932608040971	[]	[]	-1	hSpCas9	negative selection	2804713
21867341	21867364	22	-	27260157	RKO	viability	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.618439256792933	[]	[]	3	hSpCas9	negative selection	2808526
21867377	21867400	22	+	27260157	RKO	viability	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	0.866223986985777	[]	[]	8	hSpCas9	negative selection	2809491
21867376	21867399	22	-	27260157	RKO	viability	CGCGGGCAGGTGTTCGACGTGGG	MAPK1	ENSG00000100030	-0.679134301977791	[]	[]	-7	hSpCas9	negative selection	2809559
21867338	21867361	22	+	27260157	RKO	viability	CGCCCTCGCCGATGTACGAGAGG	MAPK1	ENSG00000100030	0.287802942107957	[]	[]	1	hSpCas9	negative selection	2810289
21805934	21805957	22	-	27260157	RKO	viability	TTCTCTACCAGATCCTCAGAGGG	MAPK1	ENSG00000100030	0.462807303603151	[]	[]	2	hSpCas9	negative selection	2810987
21807771	21807794	22	+	27260157	RKO	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.177269631520684	[]	[]	-1	hSpCas9	negative selection	2811717
21867430	21867453	22	+	27260157	RKO	viability	GCCGCCGCCATGTTGGCTGCCGG	MAPK1	ENSG00000100030	0.861575304084734	[]	[]	8	hSpCas9	negative selection	2815572
21807755	21807778	22	-	27260157	RKO	viability	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	1.19538794910471	[]	[]	9	hSpCas9	negative selection	2832924
21867388	21867411	22	+	27260157	RKO	viability	ACCTGCCCGCGGACCATCTCCGG	MAPK1	ENSG00000100030	1.24579190148901	[]	[]	9	hSpCas9	negative selection	2833293
21867393	21867416	22	-	27260157	RKO	viability	CGGGCCCGGAGATGGTCCGCGGG	MAPK1	ENSG00000100030	-0.371406931336112	[]	[]	-6	hSpCas9	negative selection	2835191
21867326	21867349	22	-	27260157	RKO	viability	CGGCGAGGGCGCCTACGGCATGG	MAPK1	ENSG00000100030	0.893398949767819	[]	[]	8	hSpCas9	negative selection	2837135
21867375	21867398	22	-	27260157	RKO	viability	GCGGGCAGGTGTTCGACGTGGGG	MAPK1	ENSG00000100030	0.135352666558039	[]	[]	0	hSpCas9	negative selection	2841825
21867428	21867451	22	-	27260157	RKO	viability	GGCAGCCAACATGGCGGCGGCGG	MAPK1	ENSG00000100030	1.33061379717469	[]	[]	9	hSpCas9	negative selection	2843331
21805960	21805983	22	+	27260157	RKO	viability	AGCAGATATGGTCATTGCTGAGG	MAPK1	ENSG00000100030	-0.339584812588634	[]	[]	-6	hSpCas9	negative selection	2844701
21867331	21867354	22	-	27260157	RKO	viability	TACATCGGCGAGGGCGCCTACGG	MAPK1	ENSG00000100030	0.740065927581173	[]	[]	8	hSpCas9	negative selection	2844987
21867346	21867369	22	-	27260157	RKO	viability	TACACCAACCTCTCGTACATCGG	MAPK1	ENSG00000100030	-0.341178023854973	[]	[]	-6	hSpCas9	negative selection	2870581
21807749	21807772	22	+	27260157	RKO	viability	TTATCTCCCTCAGGGTTCTCTGG	MAPK1	ENSG00000100030	0.235068778104694	[]	[]	1	hSpCas9	negative selection	2877578
21867352	21867375	22	+	27260157	SF268	viability	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	-0.262143089966578	[]	[]	-2	hSpCas9	negative selection	2878373
21807761	21807784	22	+	27260157	SF268	viability	GGGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-1.60250396058056	[]	[]	-8	hSpCas9	negative selection	2880816
21867321	21867344	22	-	27260157	SF268	viability	AGGGCGCCTACGGCATGGTGTGG	MAPK1	ENSG00000100030	-0.982852818429951	[]	[]	-7	hSpCas9	negative selection	2880843
21867341	21867364	22	-	27260157	SF268	viability	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.185515570235165	[]	[]	-1	hSpCas9	negative selection	2884656
21867377	21867400	22	+	27260157	SF268	viability	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	-0.0427688918473207	[]	[]	0	hSpCas9	negative selection	2885621
21867376	21867399	22	-	27260157	SF268	viability	CGCGGGCAGGTGTTCGACGTGGG	MAPK1	ENSG00000100030	-0.537897793826033	[]	[]	-4	hSpCas9	negative selection	2885689
21867338	21867361	22	+	27260157	SF268	viability	CGCCCTCGCCGATGTACGAGAGG	MAPK1	ENSG00000100030	0.587268006063901	[]	[]	8	hSpCas9	negative selection	2886419
21805934	21805957	22	-	27260157	SF268	viability	TTCTCTACCAGATCCTCAGAGGG	MAPK1	ENSG00000100030	-0.952844892660621	[]	[]	-6	hSpCas9	negative selection	2887117
21807771	21807794	22	+	27260157	SF268	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.521641257709233	[]	[]	-4	hSpCas9	negative selection	2887847
21867430	21867453	22	+	27260157	SF268	viability	GCCGCCGCCATGTTGGCTGCCGG	MAPK1	ENSG00000100030	1.069289979181	[]	[]	9	hSpCas9	negative selection	2891702
21807755	21807778	22	-	27260157	SF268	viability	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	-0.403607040903706	[]	[]	-3	hSpCas9	negative selection	2909054
21867388	21867411	22	+	27260157	SF268	viability	ACCTGCCCGCGGACCATCTCCGG	MAPK1	ENSG00000100030	0.294788949357023	[]	[]	4	hSpCas9	negative selection	2909423
21867393	21867416	22	-	27260157	SF268	viability	CGGGCCCGGAGATGGTCCGCGGG	MAPK1	ENSG00000100030	-0.173810242260481	[]	[]	-1	hSpCas9	negative selection	2911321
21867326	21867349	22	-	27260157	SF268	viability	CGGCGAGGGCGCCTACGGCATGG	MAPK1	ENSG00000100030	-0.606181634799215	[]	[]	-5	hSpCas9	negative selection	2913265
21867375	21867398	22	-	27260157	SF268	viability	GCGGGCAGGTGTTCGACGTGGGG	MAPK1	ENSG00000100030	-0.225509438336972	[]	[]	-2	hSpCas9	negative selection	2917955
21867428	21867451	22	-	27260157	SF268	viability	GGCAGCCAACATGGCGGCGGCGG	MAPK1	ENSG00000100030	0.033422138732693	[]	[]	0	hSpCas9	negative selection	2919461
21805960	21805983	22	+	27260157	SF268	viability	AGCAGATATGGTCATTGCTGAGG	MAPK1	ENSG00000100030	-1.10441199009985	[]	[]	-7	hSpCas9	negative selection	2920831
21867331	21867354	22	-	27260157	SF268	viability	TACATCGGCGAGGGCGCCTACGG	MAPK1	ENSG00000100030	-0.757121727070372	[]	[]	-6	hSpCas9	negative selection	2921117
21867346	21867369	22	-	27260157	SF268	viability	TACACCAACCTCTCGTACATCGG	MAPK1	ENSG00000100030	-1.07147547646317	[]	[]	-7	hSpCas9	negative selection	2946711
21807749	21807772	22	+	27260157	SF268	viability	TTATCTCCCTCAGGGTTCTCTGG	MAPK1	ENSG00000100030	-1.11245566512154	[]	[]	-7	hSpCas9	negative selection	2953708
21807774	21807797	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTAGGTCTGGTGCTCAAAGGGG	MAPK1	ENSG00000100030	0.014299760684419072	[4,4]	[4,3]	0	hSpCas9	positive selection	3001233
21867378	21867401	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	0.5854428046599904	[3,2]	[1,5]	9	hSpCas9	positive selection	3001234
21807755	21807778	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	0.051633162537320566	[3,3]	[3,2]	1	hSpCas9	positive selection	3001235
21805845	21805868	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	0.539277062477524	[2,2]	[3,4]	9	hSpCas9	positive selection	3001236
21807774	21807797	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTAGGTCTGGTGCTCAAAGGGG	MAPK1	ENSG00000100030	-0.4119644394858146	[4,4]	[2,1]	-6	hSpCas9	positive selection	3069091
21867378	21867401	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	-0.35136146541253904	[3,3]	[2,0]	-5	hSpCas9	positive selection	3069092
21807755	21807778	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	-0.31747800163296624	[3,3]	[0,1]	-5	hSpCas9	positive selection	3069093
21805845	21805868	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-0.5232368493505041	[2,2]	[0,1]	-7	hSpCas9	positive selection	3069094
21799045	21799068		-	24336571	A375	resistance to PLX after 7 days	CAGAATATGTGGCCACACGTTGG	MAPK1	ENSG00000100030	0.057131472856975174	[6,5]	[4,7]	2	hSpCas9	positive selection	3126372
21807771	21807794		+	24336571	A375	resistance to PLX after 7 days	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	0.535352242688949	[3,3]	[5,4]	9	hSpCas9	positive selection	3126373
21799045	21799068		-	24336571	A375	resistance to PLX after 14 days	CAGAATATGTGGCCACACGTTGG	MAPK1	ENSG00000100030	0.19148334662674027	[4,2]	[1,1]	2	hSpCas9	positive selection	3184165
21807771	21807794		+	24336571	A375	resistance to PLX after 14 days	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	0.2696215179836301	[1,7]	[2,1]	2	hSpCas9	positive selection	3184166
21799045	21799068		-	24336571	A375	viability after 7 days	CAGAATATGTGGCCACACGTTGG	MAPK1	ENSG00000100030	-1.4557024505240035	[18]	[6,5]	-9	hSpCas9	negative selection	3241958
21807771	21807794		+	24336571	A375	viability after 7 days	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.8955541162146432	[7]	[3,3]	-8	hSpCas9	negative selection	3241959
21799045	21799068		-	24336571	A375	viability after 14 days	CAGAATATGTGGCCACACGTTGG	MAPK1	ENSG00000100030	-1.9873541488913933	[18]	[4,2]	-9	hSpCas9	negative selection	3299751
21807771	21807794		+	24336571	A375	viability after 14 days	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.6039619318921494	[7]	[1,7]	-6	hSpCas9	negative selection	3299752
21788773	21788796	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	0.08740121000352279	[143,143]	[0,0]	0	hSpCas9	positive selection	3378477
21799050	21799073	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	1.2202368927106149	[393,393]	[5,5]	5	hSpCas9	positive selection	3378478
21807771	21807794	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	0.9905396707509337	[76,76]	[0,0]	4	hSpCas9	positive selection	3378479
21807773	21807796	22	+	26780180	HT29	viability (Avana library 4 designs)	AGTAGGTCTGGTGCTCAAAGGGG	MAPK1	ENSG00000100030	3.89414548623916	[]	[]	9	hSpCas9	negative selection	3438877
21867377	21867400	22	+	26780180	HT29	viability (Avana library 4 designs)	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	2.96710709848083	[]	[]	8	hSpCas9	negative selection	3438878
21807755	21807778	22	-	26780180	HT29	viability (Avana library 4 designs)	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	4.31308820082237	[]	[]	9	hSpCas9	negative selection	3438879
21805844	21805867	22	+	26780180	HT29	viability (Avana library 4 designs)	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	4.12920640479868	[]	[]	9	hSpCas9	negative selection	3438880
21807755	21807778	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	-10.7600758115411	[]	[]	-8	hSpCas9	negative selection	3528346
21805844	21805867	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-8.62099065682524	[]	[]	-7	hSpCas9	negative selection	3528347
21867377	21867400	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	-0.27537267043863	[]	[]	0	hSpCas9	negative selection	3528348
21807773	21807796	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTAGGTCTGGTGCTCAAAGGGG	MAPK1	ENSG00000100030	-2.98269504668426	[]	[]	-4	hSpCas9	negative selection	3528349
21805862	21805885	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-9.97845757936595	[]	[]	-7	hSpCas9	negative selection	3528350
21807756	21807779	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	-10.2413068394544	[]	[]	-7	hSpCas9	negative selection	3528351
21807755	21807778	22	-	26780180	A375	viability (Avana lentiGuide)	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	28.4168283380394	[]	[]	9	hSpCas9	negative selection	3637005
21805844	21805867	22	+	26780180	A375	viability (Avana lentiGuide)	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	19.2528555317529	[]	[]	8	hSpCas9	negative selection	3637006
21867377	21867400	22	+	26780180	A375	viability (Avana lentiGuide)	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	13.8958074787922	[]	[]	7	hSpCas9	negative selection	3637007
21807773	21807796	22	+	26780180	A375	viability (Avana lentiGuide)	AGTAGGTCTGGTGCTCAAAGGGG	MAPK1	ENSG00000100030	21.5960198557561	[]	[]	9	hSpCas9	negative selection	3637008
21805862	21805885	22	+	26780180	A375	viability (Avana lentiGuide)	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	27.9038649940515	[]	[]	9	hSpCas9	negative selection	3637009
21807756	21807779	22	-	26780180	A375	viability (Avana lentiGuide)	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	25.0299238626901	[]	[]	9	hSpCas9	negative selection	3637010
21807755	21807778	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	-0.6834941733867465	[5]	[3,2]	-7	hSpCas9	positive selection	3745664
21805844	21805867	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-0.1344097048133182	[4]	[4,2]	-2	hSpCas9	positive selection	3745665
21867377	21867400	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	-0.08622483467945113	[4]	[4,3]	-1	hSpCas9	positive selection	3745666
21807773	21807796	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTAGGTCTGGTGCTCAAAGGGG	MAPK1	ENSG00000100030	0.009578624416515635	[6]	[6,5]	0	hSpCas9	positive selection	3745667
21805862	21805885	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-0.10922244258716324	[4]	[4,3]	-2	hSpCas9	positive selection	3745668
21807756	21807779	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	-0.658807092067095	[4]	[3,1]	-7	hSpCas9	positive selection	3745669
21807755	21807778	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACTGCCAGAGAACCCTGAGGG	MAPK1	ENSG00000100030	-0.1654214068407595	[5]	[3,4]	-2	hSpCas9	positive selection	3854271
21805844	21805867	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-0.5042730713451108	[5]	[3,2]	-6	hSpCas9	positive selection	3854272
21867377	21867400	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACGTCGAACACCTGCCCGCGG	MAPK1	ENSG00000100030	-0.6019997653068824	[5]	[0,4]	-6	hSpCas9	positive selection	3854273
21807773	21807796	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTAGGTCTGGTGCTCAAAGGGG	MAPK1	ENSG00000100030	-0.055292756561258344	[6]	[4,5]	-1	hSpCas9	positive selection	3854274
21805862	21805885	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-0.6943076547455208	[5]	[2,2]	-7	hSpCas9	positive selection	3854275
21807756	21807779	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	-0.8007050549684432	[5]	[0,4]	-7	hSpCas9	positive selection	3854276
21788782	21788805	22	-	26780180	A375	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.0576679884198789	[]	[]	0	hSpCas9	negative selection	3959799
21807771	21807794	22	+	26780180	A375	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	1.56736521080937	[]	[]	8	hSpCas9	negative selection	3959800
21788773	21788796	22	+	26780180	A375	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	2.05820347224387	[]	[]	9	hSpCas9	negative selection	3959801
21805900	21805923	22	+	26780180	A375	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	1.20558717349692	[]	[]	6	hSpCas9	negative selection	3959802
21799050	21799073	22	+	26780180	A375	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	2.25342720827718	[]	[]	9	hSpCas9	negative selection	3959803
21806026	21806049	22	-	26780180	A375	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	2.52503421224022	[]	[]	9	hSpCas9	negative selection	3959804
21788782	21788805	22	-	26780180	HT29	viability (GeCKOv2 library)	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.13495052252554	[]	[]	0	hSpCas9	negative selection	4067765
21807771	21807794	22	+	26780180	HT29	viability (GeCKOv2 library)	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	2.12136057694686	[]	[]	9	hSpCas9	negative selection	4067766
21788773	21788796	22	+	26780180	HT29	viability (GeCKOv2 library)	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	2.18886410463351	[]	[]	9	hSpCas9	negative selection	4067767
21805900	21805923	22	+	26780180	HT29	viability (GeCKOv2 library)	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	1.37759666748426	[]	[]	7	hSpCas9	negative selection	4067768
21799050	21799073	22	+	26780180	HT29	viability (GeCKOv2 library)	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	1.65655589226605	[]	[]	8	hSpCas9	negative selection	4067769
21806026	21806049	22	-	26780180	HT29	viability (GeCKOv2 library)	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	2.95592627634668	[]	[]	9	hSpCas9	negative selection	4067770
21799045	21799068	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGAATATGTGGCCACACGTTGG	MAPK1	ENSG00000100030	-0.6217042547018555	[2]	[0,0]	-9	hSpCas9	positive selection	4150589
21807771	21807794	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.17169298504224828	[2]	[1,0]	-4	hSpCas9	positive selection	4150590
21799045	21799068	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGAATATGTGGCCACACGTTGG	MAPK1	ENSG00000100030	-0.7897170284190497	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4214611
21807771	21807794	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.08401020601130221	[2]	[0,2,1,0]	-1	hSpCas9	positive selection	4214612
21805900	21805923	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.023021485780860995	[2]	[2,0]	0	hSpCas9	positive selection	4281906
21788782	21788805	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.17124883629354276	[4]	[4,2]	3	hSpCas9	positive selection	4281907
21806026	21806049	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.3587459293263993	[3]	[2,1]	-6	hSpCas9	positive selection	4281908
21788773	21788796	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.8182486118665712	[2]	[1,0]	-9	hSpCas9	positive selection	4346164
21799050	21799073	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.004532730389695094	[3]	[3,2]	0	hSpCas9	positive selection	4346165
21807771	21807794	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	0.043345021679347506	[2]	[2,1]	0	hSpCas9	positive selection	4346166
21788774	21788796	22	+	27760321	OCIAML3	viability	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.058988170477626056	[44,45]	[32,35]	0	hSpCas9	negative selection	4416711
21799088	21799110	22	+	27760321	OCIAML3	viability	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-0.25598242943081334	[753,652]	[472,441]	-3	hSpCas9	negative selection	4416712
21805901	21805923	22	+	27760321	OCIAML3	viability	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.0699853242829952	[318,265]	[203,233]	-1	hSpCas9	negative selection	4416713
21806017	21806039	22	-	27760321	OCIAML3	viability	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	0.35633227633432085	[42,31]	[8,73]	4	hSpCas9	negative selection	4416714
21807762	21807784	22	+	27760321	OCIAML3	viability	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	0.27065049332020774	[615,629]	[558,630]	3	hSpCas9	negative selection	4416715
21788774	21788796	22	+	27760321	OCIAML2	viability	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.7983644175219466	[44,45]	[25,14]	-7	hSpCas9	negative selection	4500174
21799088	21799110	22	+	27760321	OCIAML2	viability	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-2.1621273753052774	[753,652]	[131,119]	-9	hSpCas9	negative selection	4500175
21805901	21805923	22	+	27760321	OCIAML2	viability	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.09315489433366186	[318,265]	[213,229]	-1	hSpCas9	negative selection	4500176
21806017	21806039	22	-	27760321	OCIAML2	viability	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	-0.7261219073832175	[42,31]	[12,24]	-6	hSpCas9	negative selection	4500177
21807762	21807784	22	+	27760321	OCIAML2	viability	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-0.8878158264740532	[615,629]	[260,289]	-7	hSpCas9	negative selection	4500178
21788774	21788796	22	+	27760321	MV411	viability	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	2.640980569158771	[44,45]	[271,61]	9	hSpCas9	negative selection	4583637
21799088	21799110	22	+	27760321	MV411	viability	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-1.1414208709361995	[753,652]	[85,395]	-6	hSpCas9	negative selection	4583638
21805901	21805923	22	+	27760321	MV411	viability	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	1.1280737035347435	[318,265]	[332,550]	8	hSpCas9	negative selection	4583639
21806017	21806039	22	-	27760321	MV411	viability	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	-4.616453136296475	[42,31]	[0,0]	-9	hSpCas9	negative selection	4583640
21807762	21807784	22	+	27760321	MV411	viability	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-0.3183950702753122	[615,629]	[195,533]	-2	hSpCas9	negative selection	4583641
21788774	21788796	22	+	27760321	HL60	viability	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	1.9874405191250903	[44,45]	[147,147]	9	hSpCas9	negative selection	4667100
21799088	21799110	22	+	27760321	HL60	viability	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-0.4859729680015341	[753,652]	[367,452]	-5	hSpCas9	negative selection	4667101
21805901	21805923	22	+	27760321	HL60	viability	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.3261861697667731	[318,265]	[291,304]	4	hSpCas9	negative selection	4667102
21806017	21806039	22	-	27760321	HL60	viability	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	1.2790810228655323	[42,31]	[79,66]	9	hSpCas9	negative selection	4667103
21807762	21807784	22	+	27760321	HL60	viability	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-0.00985164109775949	[615,629]	[476,539]	0	hSpCas9	negative selection	4667104
21788774	21788796	22	+	27760321	HT1080	viability	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-2.9976703038052372	[45,35]	[2,0]	-7	hSpCas9	negative selection	4750563
21799088	21799110	22	+	27760321	HT1080	viability	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-4.3932539540792455	[652,509]	[0,21]	-8	hSpCas9	negative selection	4750564
21805901	21805923	22	+	27760321	HT1080	viability	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-3.8063953610587626	[265,207]	[11,0]	-8	hSpCas9	negative selection	4750565
21806017	21806039	22	-	27760321	HT1080	viability	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	-3.505162899635366	[31,24]	[0,0]	-7	hSpCas9	negative selection	4750566
21807762	21807784	22	+	27760321	HT1080	viability	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-5.399147138737479	[629,491]	[0,9]	-8	hSpCas9	negative selection	4750567
21788774	21788796	22	+	27760321	HT29	viability after 7 days	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.0438212353294154	[45,35]	[84,15,56]	0	hSpCas9	negative selection	4834026
21799088	21799110	22	+	27760321	HT29	viability after 7 days	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-0.3093983737727936	[652,509]	[834,364,640]	-4	hSpCas9	negative selection	4834027
21805901	21805923	22	+	27760321	HT29	viability after 7 days	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.06334495856017452	[265,207]	[302,215,429]	1	hSpCas9	negative selection	4834028
21806017	21806039	22	-	27760321	HT29	viability after 7 days	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	-0.8153559675825508	[31,24]	[0,49,8]	-8	hSpCas9	negative selection	4834029
21807762	21807784	22	+	27760321	HT29	viability after 7 days	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-0.33859719620205175	[629,491]	[510,430,753]	-5	hSpCas9	negative selection	4834030
21788774	21788796	22	+	27760321	HT29	viability after 25 days	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-2.457643694198956	[45,35]	[0,16,7]	-8	hSpCas9	negative selection	4917489
21799088	21799110	22	+	27760321	HT29	viability after 25 days	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-2.614098564779872	[652,509]	[88,74,168]	-8	hSpCas9	negative selection	4917490
21805901	21805923	22	+	27760321	HT29	viability after 25 days	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-1.300946466258594	[265,207]	[133,93,98]	-7	hSpCas9	negative selection	4917491
21806017	21806039	22	-	27760321	HT29	viability after 25 days	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	-2.7213479545782877	[31,24]	[0,0,13]	-8	hSpCas9	negative selection	4917492
21807762	21807784	22	+	27760321	HT29	viability after 25 days	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-2.7099224359684975	[629,491]	[100,125,62]	-8	hSpCas9	negative selection	4917493
21788774	21788796	22	+	27760321	HT29	viability after 22 days	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-2.7668353691309644	[45,35]	[0,18,0]	-8	hSpCas9	negative selection	5000952
21799088	21799110	22	+	27760321	HT29	viability after 22 days	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-2.0354552770086576	[652,509]	[281,122,82]	-8	hSpCas9	negative selection	5000953
21805901	21805923	22	+	27760321	HT29	viability after 22 days	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-1.3435316140544808	[265,207]	[172,58,89]	-7	hSpCas9	negative selection	5000954
21806017	21806039	22	-	27760321	HT29	viability after 22 days	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	-2.0615302591163975	[31,24]	[0,0,21]	-8	hSpCas9	negative selection	5000955
21807762	21807784	22	+	27760321	HT29	viability after 22 days	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-2.9905895635563846	[629,491]	[35,131,77]	-8	hSpCas9	negative selection	5000956
21788774	21788796	22	+	27760321	HT29	viability after 19 days	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-4.081171121444406	[45,35]	[0,0,5]	-9	hSpCas9	negative selection	5084415
21799088	21799110	22	+	27760321	HT29	viability after 19 days	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-1.9696517602877992	[652,509]	[223,121,168]	-8	hSpCas9	negative selection	5084416
21805901	21805923	22	+	27760321	HT29	viability after 19 days	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-1.010711117355355	[265,207]	[69,117,205]	-6	hSpCas9	negative selection	5084417
21806017	21806039	22	-	27760321	HT29	viability after 19 days	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	-3.591169822193916	[31,24]	[0,5,0]	-9	hSpCas9	negative selection	5084418
21807762	21807784	22	+	27760321	HT29	viability after 19 days	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-2.702601635706582	[629,491]	[145,66,87]	-8	hSpCas9	negative selection	5084419
21788774	21788796	22	+	27760321	HT29	viability after 16 days	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.6009047118123703	[45,35]	[4,43,38]	-5	hSpCas9	negative selection	5167878
21799088	21799110	22	+	27760321	HT29	viability after 16 days	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-1.4319000443598406	[652,509]	[197,329,188]	-8	hSpCas9	negative selection	5167879
21805901	21805923	22	+	27760321	HT29	viability after 16 days	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-1.9414566104549096	[265,207]	[158,15,41]	-8	hSpCas9	negative selection	5167880
21806017	21806039	22	-	27760321	HT29	viability after 16 days	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	-3.482232674326917	[31,24]	[6,0,0]	-9	hSpCas9	negative selection	5167881
21807762	21807784	22	+	27760321	HT29	viability after 16 days	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-1.391877445613874	[629,491]	[238,66,415]	-7	hSpCas9	negative selection	5167882
21788774	21788796	22	+	27760321	HT29	viability after 13 days	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.951126360603249	[45,35]	[65,4,3]	-7	hSpCas9	negative selection	5251341
21799088	21799110	22	+	27760321	HT29	viability after 13 days	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-1.66811047292776	[652,509]	[169,170,290]	-8	hSpCas9	negative selection	5251342
21805901	21805923	22	+	27760321	HT29	viability after 13 days	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.026077775150568305	[265,207]	[381,165,290]	0	hSpCas9	negative selection	5251343
21806017	21806039	22	-	27760321	HT29	viability after 13 days	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	-3.8045660623715762	[31,24]	[0,1,3]	-9	hSpCas9	negative selection	5251344
21807762	21807784	22	+	27760321	HT29	viability after 13 days	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-1.5783895249780717	[629,491]	[142,361,152]	-8	hSpCas9	negative selection	5251345
21788774	21788796	22	+	27760321	HT29	viability after 10 days	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-1.6200270915088337	[45,35]	[32,9,6]	-8	hSpCas9	negative selection	5334804
21799088	21799110	22	+	27760321	HT29	viability after 10 days	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	-0.7666725594300429	[652,509]	[319,349,603]	-7	hSpCas9	negative selection	5334805
21805901	21805923	22	+	27760321	HT29	viability after 10 days	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.604657518479512	[265,207]	[214,208,160]	-6	hSpCas9	negative selection	5334806
21806017	21806039	22	-	27760321	HT29	viability after 10 days	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	-0.20256229927545677	[31,24]	[0,68,23]	-3	hSpCas9	negative selection	5334807
21807762	21807784	22	+	27760321	HT29	viability after 10 days	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	-1.1276163569412536	[629,491]	[250,457,257]	-8	hSpCas9	negative selection	5334808
21788774	21788796	22	+	27760321	MOLM13	viability	CCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	0.28799797772946967	[44,45]	[51,13]	2	hSpCas9	negative selection	5418267
21799088	21799110	22	+	27760321	MOLM13	viability	TGGTCTGGATCTGCAACACGGG	MAPK1	ENSG00000100030	0.4902203878579323	[753,652]	[924,241]	3	hSpCas9	negative selection	5418268
21805901	21805923	22	+	27760321	MOLM13	viability	GTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	1.94905062463093	[318,265]	[848,451]	9	hSpCas9	negative selection	5418269
21806017	21806039	22	-	27760321	MOLM13	viability	TATATAGTACAGGACCTCATGG	MAPK1	ENSG00000100030	-1.4869862965953233	[42,31]	[0,12]	-7	hSpCas9	negative selection	5418270
21807762	21807784	22	+	27760321	MOLM13	viability	GGTTCTCTGGCAGTAGGTCTGG	MAPK1	ENSG00000100030	2.43951270357514	[615,629]	[3444,611]	9	hSpCas9	negative selection	5418271
21867189	21867212	22	+	27661255	K562	viability	GCGCGGACCGCGGTGAAGTCCGG	MAPK1	ENSG00000100030	0.08385596419936547	[562,382]	[447,364]	3	dCas9-KRAB	negative selection	5492179
21867206	21867229	22	+	27661255	K562	viability	GTCCGGGTTCGAGGTCGCCGCGG	MAPK1	ENSG00000100030	0.18583279231352845	[1156,1283]	[1236,995]	6	dCas9-KRAB	negative selection	5492180
21867568	21867591	22	+	27661255	K562	viability	GGAGGAAGGAAGACGCCGAGCGG	MAPK1	ENSG00000100030	0.06305043940431246	[852,807]	[771,626]	2	dCas9-KRAB	negative selection	5492181
21805900	21805923	22	+	27260156	BXPC3	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.3488110659731598	[220]	[402,226,151,394]	7	hSpCas9	negative selection	5554366
21788782	21788805	22	-	27260156	BXPC3	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.3452064511516877	[1010]	[1170,1351,1320,1562]	7	hSpCas9	negative selection	5554367
21806026	21806049	22	-	27260156	BXPC3	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.450804922620103	[842]	[584,707,561,731]	-7	hSpCas9	negative selection	5554368
21788773	21788796	22	+	27260156	BXPC3	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	0.021252813983492436	[433]	[344,524,415,574]	0	hSpCas9	negative selection	5618624
21799050	21799073	22	+	27260156	BXPC3	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.012645900696483525	[864]	[719,810,1116,1041]	0	hSpCas9	negative selection	5618625
21807771	21807794	22	+	27260156	BXPC3	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.08299171884743295	[279]	[211,327,248,323]	-2	hSpCas9	negative selection	5618626
21805900	21805923	22	+	27260156	A673	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.1815310179202152	[220]	[195,255,235,242]	-4	hSpCas9	negative selection	5675617
21788782	21788805	22	-	27260156	A673	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	-0.00402054101602678	[1010]	[1296,1146,1146,1263]	0	hSpCas9	negative selection	5675618
21806026	21806049	22	-	27260156	A673	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.7440994731030894	[842]	[665,521,590,648]	-9	hSpCas9	negative selection	5675619
21788773	21788796	22	+	27260156	A673	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.3680918005276505	[433]	[425,412,327,452]	-7	hSpCas9	negative selection	5739875
21799050	21799073	22	+	27260156	A673	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.1637456503410174	[864]	[973,856,953,928]	-4	hSpCas9	negative selection	5739876
21807771	21807794	22	+	27260156	A673	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.31755313304001354	[279]	[279,287,234,276]	-7	hSpCas9	negative selection	5739877
21805900	21805923	22	+	27260156	A375	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-1.0143175092153363	[220]	[64,157,122,163]	-8	hSpCas9	negative selection	5796868
21788782	21788805	22	-	27260156	A375	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.4375783456728739	[1010]	[1508,2200,1434,1357]	6	hSpCas9	negative selection	5796869
21806026	21806049	22	-	27260156	A375	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-1.80320230132381	[842]	[400,394,139,215]	-9	hSpCas9	negative selection	5796870
21788773	21788796	22	+	27260156	A375	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-1.8878015987210823	[433]	[150,91,149,146]	-9	hSpCas9	negative selection	5861126
21799050	21799073	22	+	27260156	A375	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.8272454113383856	[864]	[364,598,817,503]	-8	hSpCas9	negative selection	5861127
21807771	21807794	22	+	27260156	A375	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-2.260687722157385	[279]	[48,80,35,103]	-9	hSpCas9	negative selection	5861128
21805900	21805923	22	+	27260156	COLO741	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.5252509961259824	[220]	[335,126,140]	-8	hSpCas9	negative selection	5918119
21788782	21788805	22	-	27260156	COLO741	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.1750692003018448	[1010]	[1490,1359,1518]	4	hSpCas9	negative selection	5918120
21806026	21806049	22	-	27260156	COLO741	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-1.2607556330034448	[842]	[516,468,372]	-9	hSpCas9	negative selection	5918121
21788773	21788796	22	+	27260156	COLO741	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.8431009962522265	[433]	[346,401,189]	-9	hSpCas9	negative selection	5982377
21799050	21799073	22	+	27260156	COLO741	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.3733332400719698	[864]	[855,848,852]	-7	hSpCas9	negative selection	5982378
21807771	21807794	22	+	27260156	COLO741	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-1.2165907727766565	[279]	[253,106,111]	-9	hSpCas9	negative selection	5982379
21805900	21805923	22	+	27260156	CAL120	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.4786315616689273	[220]	[347,515,281]	7	hSpCas9	negative selection	6039370
21788782	21788805	22	-	27260156	CAL120	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.20677171272562744	[1010]	[1299,1670,1362]	3	hSpCas9	negative selection	6039371
21806026	21806049	22	-	27260156	CAL120	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.6471241629712896	[842]	[702,905,409]	-7	hSpCas9	negative selection	6039372
21788773	21788796	22	+	27260156	CAL120	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.2821844530578784	[433]	[315,334,657]	-4	hSpCas9	negative selection	6103628
21799050	21799073	22	+	27260156	CAL120	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.2500629620667131	[864]	[1751,1280,884]	4	hSpCas9	negative selection	6103629
21807771	21807794	22	+	27260156	CAL120	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.213656064064921	[279]	[503,188,239]	-3	hSpCas9	negative selection	6103630
21805900	21805923	22	+	27260156	CADOES1	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.05528546273429491	[220]	[190,147,232,219]	-1	hSpCas9	negative selection	6160621
21788782	21788805	22	-	27260156	CADOES1	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.44226406441261923	[1010]	[1203,1079,1347,1485]	7	hSpCas9	negative selection	6160622
21806026	21806049	22	-	27260156	CADOES1	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.5214151166564169	[842]	[494,565,630,490]	-7	hSpCas9	negative selection	6160623
21788773	21788796	22	+	27260156	CADOES1	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.03487981287063378	[433]	[389,336,553,290]	0	hSpCas9	negative selection	6224879
21799050	21799073	22	+	27260156	CADOES1	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.22660840636390034	[864]	[976,817,1001,968]	4	hSpCas9	negative selection	6224880
21807771	21807794	22	+	27260156	CADOES1	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.1527144814892314	[279]	[184,288,286,173]	-3	hSpCas9	negative selection	6224881
21805900	21805923	22	+	27260156	EWS502	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.3302250364613286	[220]	[199,181,195,162]	-5	hSpCas9	negative selection	6281872
21788782	21788805	22	-	27260156	EWS502	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.3786939118697459	[1010]	[1218,1141,1705,1542]	6	hSpCas9	negative selection	6281873
21806026	21806049	22	-	27260156	EWS502	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.8490937470839943	[842]	[482,565,426,502]	-8	hSpCas9	negative selection	6281874
21788773	21788796	22	+	27260156	EWS502	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.8240015732226347	[433]	[198,208,328,314]	-8	hSpCas9	negative selection	6346130
21799050	21799073	22	+	27260156	EWS502	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.12583657214466193	[864]	[695,929,920,821]	-2	hSpCas9	negative selection	6346131
21807771	21807794	22	+	27260156	EWS502	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.2844223629774899	[279]	[267,156,329,217]	-5	hSpCas9	negative selection	6346132
21805900	21805923	22	+	27260156	EW8	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.2578084383434851	[220]	[164,138,175,115]	-5	hSpCas9	negative selection	6403123
21788782	21788805	22	-	27260156	EW8	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.3683422505419669	[1010]	[1366,988,852,1086]	6	hSpCas9	negative selection	6403124
21806026	21806049	22	-	27260156	EW8	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.502723809120492	[842]	[489,630,351,477]	-7	hSpCas9	negative selection	6403125
21788773	21788796	22	+	27260156	EW8	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.3208313988583621	[433]	[390,239,236,276]	-5	hSpCas9	negative selection	6467381
21799050	21799073	22	+	27260156	EW8	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.07598255404331822	[864]	[927,587,576,608]	-1	hSpCas9	negative selection	6467382
21807771	21807794	22	+	27260156	EW8	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.028372872684064965	[279]	[280,175,195,246]	0	hSpCas9	negative selection	6467383
21805900	21805923	22	+	27260156	CORL105	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.14911690649106457	[220]	[318,167,495,200]	3	hSpCas9	negative selection	6524374
21788782	21788805	22	-	27260156	CORL105	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.23562998789883371	[1010]	[1288,1143,1583,1586]	4	hSpCas9	negative selection	6524375
21806026	21806049	22	-	27260156	CORL105	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.5529007130185175	[842]	[585,699,754,658]	-7	hSpCas9	negative selection	6524376
21788773	21788796	22	+	27260156	CORL105	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.07248682078561029	[433]	[447,508,596,394]	-1	hSpCas9	negative selection	6588632
21799050	21799073	22	+	27260156	CORL105	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.08812438470120232	[864]	[1076,919,1052,1253]	1	hSpCas9	negative selection	6588633
21807771	21807794	22	+	27260156	CORL105	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	0.28032799316368	[279]	[290,248,732,370]	5	hSpCas9	negative selection	6588634
21805900	21805923	22	+	27260156	HS294T	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.1714192645068392	[220]	[103,133,65,74]	2	hSpCas9	negative selection	6645625
21788782	21788805	22	-	27260156	HS294T	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.42016981682450183	[1010]	[523,572,506,476]	5	hSpCas9	negative selection	6645626
21806026	21806049	22	-	27260156	HS294T	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.42782910875189945	[842]	[179,181,314,310]	-6	hSpCas9	negative selection	6645627
21788773	21788796	22	+	27260156	HS294T	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.14622891576870778	[433]	[195,182,107,105]	-2	hSpCas9	negative selection	6709883
21799050	21799073	22	+	27260156	HS294T	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.415880921219356	[864]	[191,217,276,335]	-5	hSpCas9	negative selection	6709884
21807771	21807794	22	+	27260156	HS294T	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.7573021579098017	[279]	[35,69,75,78]	-8	hSpCas9	negative selection	6709885
21805900	21805923	22	+	27260156	HCC44	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.09281857724649945	[220]	[304,302,236,213]	1	hSpCas9	negative selection	6766876
21788782	21788805	22	-	27260156	HCC44	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.2883407910504632	[1010]	[1905,1167,1500,1105]	5	hSpCas9	negative selection	6766877
21806026	21806049	22	-	27260156	HCC44	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-1.0738193823962239	[842]	[293,507,602,407]	-8	hSpCas9	negative selection	6766878
21788773	21788796	22	+	27260156	HCC44	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.8743010887573556	[433]	[261,239,286,285]	-8	hSpCas9	negative selection	6831134
21799050	21799073	22	+	27260156	HCC44	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.15969319931658754	[864]	[938,637,1176,834]	-3	hSpCas9	negative selection	6831135
21807771	21807794	22	+	27260156	HCC44	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-1.0894123466560748	[279]	[54,103,366,104]	-8	hSpCas9	negative selection	6831136
21805900	21805923	22	+	27260156	G402	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.23855965494332665	[220]	[148,269,186,294]	-3	hSpCas9	negative selection	6888127
21788782	21788805	22	-	27260156	G402	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.6519306436940853	[1010]	[1952,1751,2386,1658]	7	hSpCas9	negative selection	6888128
21806026	21806049	22	-	27260156	G402	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-1.0611699036977678	[842]	[575,521,315,565]	-8	hSpCas9	negative selection	6888129
21788773	21788796	22	+	27260156	G402	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.9381956122731666	[433]	[498,114,253,259]	-8	hSpCas9	negative selection	6952385
21799050	21799073	22	+	27260156	G402	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.16202046286641392	[864]	[755,1270,902,836]	-2	hSpCas9	negative selection	6952386
21807771	21807794	22	+	27260156	G402	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.4486967592511032	[279]	[386,221,191,218]	-5	hSpCas9	negative selection	6952387
21805900	21805923	22	+	27260156	L33	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.13143720110723955	[220]	[195,95,126,335]	3	hSpCas9	negative selection	7009378
21788782	21788805	22	-	27260156	L33	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.21527481329032727	[1010]	[1449,438,612,1189]	5	hSpCas9	negative selection	7009379
21806026	21806049	22	-	27260156	L33	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.10938742883575825	[842]	[809,320,456,803]	-2	hSpCas9	negative selection	7009380
21788773	21788796	22	+	27260156	L33	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	0.07560966095476579	[433]	[473,176,297,448]	1	hSpCas9	negative selection	7073636
21799050	21799073	22	+	27260156	L33	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.07029363618416984	[864]	[773,283,548,954]	-1	hSpCas9	negative selection	7073637
21807771	21807794	22	+	27260156	L33	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.1264355320358238	[279]	[224,100,207,224]	-3	hSpCas9	negative selection	7073638
21805900	21805923	22	+	27260156	K562	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.08083718759169156	[220]	[146,147,322,124]	-1	hSpCas9	negative selection	7130629
21788782	21788805	22	-	27260156	K562	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.010526536070992965	[1010]	[754,1119,1148,619]	0	hSpCas9	negative selection	7130630
21806026	21806049	22	-	27260156	K562	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-2.105827473078417	[842]	[119,64,312,184]	-9	hSpCas9	negative selection	7130631
21788773	21788796	22	+	27260156	K562	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-2.5059910882216383	[433]	[77,51,120,24]	-9	hSpCas9	negative selection	7194887
21799050	21799073	22	+	27260156	K562	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.01205966442557016	[864]	[569,704,828,947]	0	hSpCas9	negative selection	7194888
21807771	21807794	22	+	27260156	K562	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-2.0075182565776544	[279]	[31,103,13,92]	-9	hSpCas9	negative selection	7194889
21805900	21805923	22	+	27260156	HT29	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.2315391056015641	[220]	[245,242,241,189]	-4	hSpCas9	negative selection	7251880
21788782	21788805	22	-	27260156	HT29	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.18493706198562387	[1010]	[1423,1449,1477,1250]	3	hSpCas9	negative selection	7251881
21806026	21806049	22	-	27260156	HT29	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.6865659540380584	[842]	[665,658,679,551]	-8	hSpCas9	negative selection	7251882
21788773	21788796	22	+	27260156	HT29	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.2482526418614136	[433]	[589,407,468,328]	-5	hSpCas9	negative selection	7316138
21799050	21799073	22	+	27260156	HT29	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.3088130193150542	[864]	[1005,838,898,677]	-5	hSpCas9	negative selection	7316139
21807771	21807794	22	+	27260156	HT29	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.4878171033829787	[279]	[271,260,170,265]	-7	hSpCas9	negative selection	7316140
21805900	21805923	22	+	27260156	MHHES1	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.025408700162273368	[220]	[365,237,208,186]	0	hSpCas9	negative selection	7373131
21788782	21788805	22	-	27260156	MHHES1	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.24295996833587807	[1010]	[1513,1688,1339,961]	4	hSpCas9	negative selection	7373132
21806026	21806049	22	-	27260156	MHHES1	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.58490038656694	[842]	[1122,516,666,329]	-8	hSpCas9	negative selection	7373133
21788773	21788796	22	+	27260156	MHHES1	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	0.03313047792242087	[433]	[641,497,531,365]	0	hSpCas9	negative selection	7437389
21799050	21799073	22	+	27260156	MHHES1	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.027466811686827852	[864]	[1175,1057,967,816]	0	hSpCas9	negative selection	7437390
21807771	21807794	22	+	27260156	MHHES1	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.05308657163021313	[279]	[712,306,108,161]	-1	hSpCas9	negative selection	7437391
21805900	21805923	22	+	27260156	MEWO	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.0986374806112923	[220]	[95,185,357]	2	hSpCas9	negative selection	7494382
21788782	21788805	22	-	27260156	MEWO	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.23542910374217474	[1010]	[1162,1087,1098]	5	hSpCas9	negative selection	7494383
21806026	21806049	22	-	27260156	MEWO	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.5713908771409524	[842]	[677,463,478]	-8	hSpCas9	negative selection	7494384
21788773	21788796	22	+	27260156	MEWO	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.44644448238073825	[433]	[363,221,320]	-7	hSpCas9	negative selection	7558640
21799050	21799073	22	+	27260156	MEWO	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.014057807609928363	[864]	[951,849,630]	0	hSpCas9	negative selection	7558641
21807771	21807794	22	+	27260156	MEWO	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.8474023289554572	[279]	[223,131,95]	-9	hSpCas9	negative selection	7558642
21805900	21805923	22	+	27260156	LNCAPCLONEFGC	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.14971028759233973	[220]	[258,195,240,195]	2	hSpCas9	negative selection	7615633
21788782	21788805	22	-	27260156	LNCAPCLONEFGC	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.34036274292987434	[1010]	[1143,950,1197,1363]	5	hSpCas9	negative selection	7615634
21806026	21806049	22	-	27260156	LNCAPCLONEFGC	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.45853020785262427	[842]	[568,476,700,501]	-6	hSpCas9	negative selection	7615635
21788773	21788796	22	+	27260156	LNCAPCLONEFGC	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.33034263812782766	[433]	[393,255,334,270]	-5	hSpCas9	negative selection	7679891
21799050	21799073	22	+	27260156	LNCAPCLONEFGC	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.25405126681221624	[864]	[703,856,1252,979]	4	hSpCas9	negative selection	7679892
21807771	21807794	22	+	27260156	LNCAPCLONEFGC	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.46073071666054577	[279]	[113,175,271,189]	-6	hSpCas9	negative selection	7679893
21805900	21805923	22	+	27260156	PANC0327	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.31162135962155224	[220]	[204,43,77,323]	-4	hSpCas9	negative selection	7736884
21788782	21788805	22	-	27260156	PANC0327	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.3101074099814394	[1010]	[1274,770,1233,1230]	4	hSpCas9	negative selection	7736885
21806026	21806049	22	-	27260156	PANC0327	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-1.0886275962700092	[842]	[384,191,516,337]	-8	hSpCas9	negative selection	7736886
21788773	21788796	22	+	27260156	PANC0327	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-2.2822326111620783	[433]	[110,75,61,70]	-9	hSpCas9	negative selection	7801142
21799050	21799073	22	+	27260156	PANC0327	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.41960474871952075	[864]	[646,637,346,662]	-6	hSpCas9	negative selection	7801143
21807771	21807794	22	+	27260156	PANC0327	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.9221793569473026	[279]	[92,191,119,108]	-8	hSpCas9	negative selection	7801144
21805900	21805923	22	+	27260156	NCIH2009	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.24736055514688693	[220]	[404,506,191]	3	hSpCas9	negative selection	7858135
21788782	21788805	22	-	27260156	NCIH2009	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.5067219764766846	[1010]	[2270,1654,2149]	7	hSpCas9	negative selection	7858136
21806026	21806049	22	-	27260156	NCIH2009	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-1.1607190337077316	[842]	[625,535,436]	-8	hSpCas9	negative selection	7858137
21788773	21788796	22	+	27260156	NCIH2009	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.8561615002861622	[433]	[317,278,404]	-8	hSpCas9	negative selection	7922393
21799050	21799073	22	+	27260156	NCIH2009	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.14426206305468003	[864]	[1234,1022,1049]	-2	hSpCas9	negative selection	7922394
21807771	21807794	22	+	27260156	NCIH2009	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.1959292021558311	[279]	[354,487,180]	-3	hSpCas9	negative selection	7922395
21805900	21805923	22	+	27260156	NCIH1373	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.24992656289123882	[220]	[206,134,328,42]	-2	hSpCas9	negative selection	7979386
21788782	21788805	22	-	27260156	NCIH1373	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.7219612164663927	[1010]	[2056,1127,1959,647]	7	hSpCas9	negative selection	7979387
21806026	21806049	22	-	27260156	NCIH1373	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.8549195373370128	[842]	[474,617,567,104]	-7	hSpCas9	negative selection	7979388
21788773	21788796	22	+	27260156	NCIH1373	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.6870373783039649	[433]	[122,198,575,74]	-6	hSpCas9	negative selection	8043644
21799050	21799073	22	+	27260156	NCIH1373	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.21130560050643254	[864]	[1060,1158,941,347]	2	hSpCas9	negative selection	8043645
21807771	21807794	22	+	27260156	NCIH1373	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.5378946623871096	[279]	[335,215,188,35]	-5	hSpCas9	negative selection	8043646
21805900	21805923	22	+	27260156	PATU8902	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.24068163777824103	[220]	[261,345,248,175]	-2	hSpCas9	negative selection	8100637
21788782	21788805	22	-	27260156	PATU8902	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.5318449594419545	[1010]	[2363,2685,1340,1896]	5	hSpCas9	negative selection	8100638
21806026	21806049	22	-	27260156	PATU8902	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-1.0781120610202	[842]	[378,651,514,704]	-7	hSpCas9	negative selection	8100639
21788773	21788796	22	+	27260156	PATU8902	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.4481455224198176	[433]	[661,524,359,212]	-4	hSpCas9	negative selection	8164895
21799050	21799073	22	+	27260156	PATU8902	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.4221852955405757	[864]	[1877,1579,880,2383]	4	hSpCas9	negative selection	8164896
21807771	21807794	22	+	27260156	PATU8902	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.39749483042496025	[279]	[128,400,225,466]	-4	hSpCas9	negative selection	8164897
21805900	21805923	22	+	27260156	PANC1	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.14677690504002538	[220]	[191,219,279,156]	2	hSpCas9	negative selection	8221888
21788782	21788805	22	-	27260156	PANC1	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.27506786698033414	[1010]	[835,1472,1056,930]	4	hSpCas9	negative selection	8221889
21806026	21806049	22	-	27260156	PANC1	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-1.1197430840760245	[842]	[270,418,480,198]	-8	hSpCas9	negative selection	8221890
21788773	21788796	22	+	27260156	PANC1	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.9734667258798985	[433]	[128,234,133,256]	-8	hSpCas9	negative selection	8286146
21799050	21799073	22	+	27260156	PANC1	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.055993692111533266	[864]	[578,968,983,616]	0	hSpCas9	negative selection	8286147
21807771	21807794	22	+	27260156	PANC1	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-1.1059258290118037	[279]	[83,159,122,91]	-8	hSpCas9	negative selection	8286148
21805900	21805923	22	+	27260156	PANC0813	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.14122124400594038	[220]	[152,344,228,207]	-2	hSpCas9	negative selection	8343139
21788782	21788805	22	-	27260156	PANC0813	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.5850751266665208	[1010]	[1690,1543,1442,2399]	8	hSpCas9	negative selection	8343140
21806026	21806049	22	-	27260156	PANC0813	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.5131196316970086	[842]	[725,887,484,677]	-6	hSpCas9	negative selection	8343141
21788773	21788796	22	+	27260156	PANC0813	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.5827614393358475	[433]	[271,418,262,396]	-7	hSpCas9	negative selection	8407397
21799050	21799073	22	+	27260156	PANC0813	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.12107843653035333	[864]	[1173,888,898,802]	-2	hSpCas9	negative selection	8407398
21807771	21807794	22	+	27260156	PANC0813	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.6429506812486238	[279]	[232,227,188,194]	-7	hSpCas9	negative selection	8407399
21805900	21805923	22	+	27260156	RDES	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.37672599113252403	[220]	[162,198,261,155]	-6	hSpCas9	negative selection	8464390
21788782	21788805	22	-	27260156	RDES	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.3963812520262624	[1010]	[1198,1432,1682,1904]	6	hSpCas9	negative selection	8464391
21806026	21806049	22	-	27260156	RDES	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.72818389584752	[842]	[428,497,815,640]	-8	hSpCas9	negative selection	8464392
21788773	21788796	22	+	27260156	RDES	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.3033900346038194	[433]	[249,423,401,590]	-5	hSpCas9	negative selection	8528648
21799050	21799073	22	+	27260156	RDES	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.004988077791444945	[864]	[879,966,988,1180]	0	hSpCas9	negative selection	8528649
21807771	21807794	22	+	27260156	RDES	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.22332442193338065	[279]	[220,317,271,293]	-4	hSpCas9	negative selection	8528650
21805900	21805923	22	+	27260156	PC3	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.1599078082542793	[220]	[214,177,384,245]	3	hSpCas9	negative selection	8585641
21788782	21788805	22	-	27260156	PC3	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.06854739856436631	[1010]	[762,822,1711,1217]	1	hSpCas9	negative selection	8585642
21806026	21806049	22	-	27260156	PC3	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.41046353101479777	[842]	[491,532,1150,543]	-7	hSpCas9	negative selection	8585643
21788773	21788796	22	+	27260156	PC3	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.30943061402506833	[433]	[179,432,561,343]	-6	hSpCas9	negative selection	8649899
21799050	21799073	22	+	27260156	PC3	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.002593858907069535	[864]	[476,1012,1531,773]	0	hSpCas9	negative selection	8649900
21807771	21807794	22	+	27260156	PC3	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.25307217603133736	[279]	[218,162,410,188]	-5	hSpCas9	negative selection	8649901
21805900	21805923	22	+	27260156	PATU8988T	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.7988188366477329	[220]	[467,393,389,223]	9	hSpCas9	negative selection	8706892
21788782	21788805	22	-	27260156	PATU8988T	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.16920080488922284	[1010]	[968,1462,925,1069]	3	hSpCas9	negative selection	8706893
21806026	21806049	22	-	27260156	PATU8988T	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.579561947949106	[842]	[555,466,546,607]	-7	hSpCas9	negative selection	8706894
21788773	21788796	22	+	27260156	PATU8988T	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.34028773087460945	[433]	[312,479,220,325]	-5	hSpCas9	negative selection	8771150
21799050	21799073	22	+	27260156	PATU8988T	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.3031522831062603	[864]	[445,817,626,845]	-5	hSpCas9	negative selection	8771151
21807771	21807794	22	+	27260156	PATU8988T	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	0.2709280375645229	[279]	[247,465,146,471]	4	hSpCas9	negative selection	8771152
21805900	21805923	22	+	27260156	T47D	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.11055630779318726	[220]	[336,212,199,205]	-2	hSpCas9	negative selection	8828143
21788782	21788805	22	-	27260156	T47D	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.2573161975634888	[1010]	[1457,1238,1486,1461]	5	hSpCas9	negative selection	8828144
21806026	21806049	22	-	27260156	T47D	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.32208553700853193	[842]	[909,830,620,778]	-6	hSpCas9	negative selection	8828145
21788773	21788796	22	+	27260156	T47D	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	0.013734439563789572	[433]	[479,480,450,636]	0	hSpCas9	negative selection	8892401
21799050	21799073	22	+	27260156	T47D	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.13010295620434598	[864]	[1079,1172,1018,1134]	2	hSpCas9	negative selection	8892402
21807771	21807794	22	+	27260156	T47D	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	0.06504501828064291	[279]	[226,352,313,473]	1	hSpCas9	negative selection	8892403
21805900	21805923	22	+	27260156	SU8686	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.14180052837279422	[220]	[131,177,237,475]	2	hSpCas9	negative selection	8949394
21788782	21788805	22	-	27260156	SU8686	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.3851425149466863	[1010]	[1021,1171,1447,1702]	6	hSpCas9	negative selection	8949395
21806026	21806049	22	-	27260156	SU8686	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.2896575186731235	[842]	[566,538,752,947]	-5	hSpCas9	negative selection	8949396
21788773	21788796	22	+	27260156	SU8686	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	0.03183495546592552	[433]	[266,404,358,806]	0	hSpCas9	negative selection	9013652
21799050	21799073	22	+	27260156	SU8686	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.20382086341254768	[864]	[999,719,1053,1246]	3	hSpCas9	negative selection	9013653
21807771	21807794	22	+	27260156	SU8686	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.026868062302723983	[279]	[110,126,314,631]	0	hSpCas9	negative selection	9013654
21805900	21805923	22	+	27260156	SKES1	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.1522943342431986	[220]	[151,219,265,153]	-3	hSpCas9	negative selection	9070645
21788782	21788805	22	-	27260156	SKES1	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.21765416209429267	[1010]	[1426,1230,1044,1035]	4	hSpCas9	negative selection	9070646
21806026	21806049	22	-	27260156	SKES1	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.8774574401725004	[842]	[522,415,574,329]	-9	hSpCas9	negative selection	9070647
21788773	21788796	22	+	27260156	SKES1	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	0.05563841084580326	[433]	[548,505,443,330]	1	hSpCas9	negative selection	9134903
21799050	21799073	22	+	27260156	SKES1	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.016898181208780727	[864]	[748,921,949,851]	0	hSpCas9	negative selection	9134904
21807771	21807794	22	+	27260156	SKES1	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.7082402651884628	[279]	[139,186,269,90]	-9	hSpCas9	negative selection	9134905
21805900	21805923	22	+	27260156	TOV112D	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	0.10630559695921771	[220]	[332,274,206,156]	2	hSpCas9	negative selection	9191896
21788782	21788805	22	-	27260156	TOV112D	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	-0.10131839299045042	[1010]	[795,1271,927,848]	-2	hSpCas9	negative selection	9191897
21806026	21806049	22	-	27260156	TOV112D	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.7956217609382946	[842]	[487,648,580,272]	-9	hSpCas9	negative selection	9191898
21788773	21788796	22	+	27260156	TOV112D	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.26160249083214326	[433]	[262,280,431,442]	-5	hSpCas9	negative selection	9256154
21799050	21799073	22	+	27260156	TOV112D	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.0545277939538521	[864]	[719,1175,1027,730]	1	hSpCas9	negative selection	9256155
21807771	21807794	22	+	27260156	TOV112D	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.2547103695770586	[279]	[178,113,402,209]	-5	hSpCas9	negative selection	9256156
21805900	21805923	22	+	27260156	TC71	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.14080581151929228	[220]	[133,264,198,266]	-4	hSpCas9	negative selection	9313147
21788782	21788805	22	-	27260156	TC71	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.14843517848321874	[1010]	[1050,1209,1264,1284]	4	hSpCas9	negative selection	9313148
21806026	21806049	22	-	27260156	TC71	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.5327123653288275	[842]	[698,518,592,690]	-9	hSpCas9	negative selection	9313149
21788773	21788796	22	+	27260156	TC71	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.2591087189679213	[433]	[362,406,398,385]	-6	hSpCas9	negative selection	9377405
21799050	21799073	22	+	27260156	TC71	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	-0.06383542988207791	[864]	[913,809,816,1016]	-2	hSpCas9	negative selection	9377406
21807771	21807794	22	+	27260156	TC71	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.34588268062877237	[279]	[225,208,278,228]	-7	hSpCas9	negative selection	9377407
21805900	21805923	22	+	27260156	TC32	viability	GGTGCAGAACGTTAGCTGAATGG	MAPK1	ENSG00000100030	-0.2566970018306849	[220]	[109,91,355,200]	-5	hSpCas9	negative selection	9434398
21788782	21788805	22	-	27260156	TC32	viability	ACACCAAGTCCATTGATATTTGG	MAPK1	ENSG00000100030	0.2327405458324905	[1010]	[1316,636,1283,1360]	4	hSpCas9	negative selection	9434399
21806026	21806049	22	-	27260156	TC32	viability	TGCAAACAGATATATAGTACAGG	MAPK1	ENSG00000100030	-0.43977367988424976	[842]	[629,469,682,569]	-7	hSpCas9	negative selection	9434400
21788773	21788796	22	+	27260156	TC32	viability	GCCTACAGACCAAATATCAATGG	MAPK1	ENSG00000100030	-0.30979814652850535	[433]	[308,285,369,357]	-5	hSpCas9	negative selection	9498656
21799050	21799073	22	+	27260156	TC32	viability	GTGTGGCCACATATTCTGTCAGG	MAPK1	ENSG00000100030	0.08771058980580437	[864]	[749,590,1057,1175]	1	hSpCas9	negative selection	9498657
21807771	21807794	22	+	27260156	TC32	viability	GCAGTAGGTCTGGTGCTCAAAGG	MAPK1	ENSG00000100030	-0.5324897326555923	[279]	[175,126,287,164]	-7	hSpCas9	negative selection	9498658
21769297	21769320	22	+	27869803	HPAFII	viability after 27 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	0.8129296016795863	[475]	[521,370,NaN]	6	hSpCas9	negative selection	9579983
21799092	21799115	22	+	27869803	HPAFII	viability after 27 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	1.731917184870393	[347]	[886,374,NaN]	9	hSpCas9	negative selection	9579984
21805858	21805881	22	+	27869803	HPAFII	viability after 27 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	0.3650019086351129	[249]	[117,211,NaN]	3	hSpCas9	negative selection	9579985
21807772	21807795	22	+	27869803	HPAFII	viability after 27 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.9408889589668604	[411]	[525,323,NaN]	7	hSpCas9	negative selection	9579986
21867341	21867364	22	-	27869803	HPAFII	viability after 27 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.14284844127877	[347]	[219,186,NaN]	1	hSpCas9	negative selection	9579987
21867352	21867375	22	+	27869803	HPAFII	viability after 27 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	0.959812216104774	[337]	[541,181,NaN]	7	hSpCas9	negative selection	9579988
21769297	21769320	22	+	27869803	HPAFII	viability after 15 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	0.7281963037893645	[475]	[1045,723,NaN]	7	hSpCas9	negative selection	9662432
21799092	21799115	22	+	27869803	HPAFII	viability after 15 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.7483928016295369	[347]	[980,408,NaN]	8	hSpCas9	negative selection	9662433
21805858	21805881	22	+	27869803	HPAFII	viability after 15 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	0.09624034396128667	[249]	[293,282,NaN]	1	hSpCas9	negative selection	9662434
21807772	21807795	22	+	27869803	HPAFII	viability after 15 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.7048894102676574	[411]	[767,692,NaN]	7	hSpCas9	negative selection	9662435
21867341	21867364	22	-	27869803	HPAFII	viability after 15 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.24504192058822416	[347]	[486,208,NaN]	-3	hSpCas9	negative selection	9662436
21867352	21867375	22	+	27869803	HPAFII	viability after 15 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	0.8328233355175774	[337]	[905,485,NaN]	8	hSpCas9	negative selection	9662437
21769297	21769320	22	+	27869803	ASPC1	viability after 36 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	0.01706801625762422	[1306]	[589,376,433]	0	hSpCas9	negative selection	9744881
21799092	21799115	22	+	27869803	ASPC1	viability after 36 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.4470787816118853	[922]	[152,857,302]	4	hSpCas9	negative selection	9744882
21805858	21805881	22	+	27869803	ASPC1	viability after 36 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	1.1942332672394462	[576]	[953,329,213]	9	hSpCas9	negative selection	9744883
21807772	21807795	22	+	27869803	ASPC1	viability after 36 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	-0.283151152597616	[871]	[454,327,41]	-3	hSpCas9	negative selection	9744884
21867341	21867364	22	-	27869803	ASPC1	viability after 36 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.5880437562469684	[1010]	[657,321,600]	6	hSpCas9	negative selection	9744885
21867352	21867375	22	+	27869803	ASPC1	viability after 36 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	0.8604098886638742	[1316]	[1101,1115,414]	8	hSpCas9	negative selection	9744886
21769297	21769320	22	+	27869803	PATU8988S	viability after 35 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	0.2620362072325987	[815]	[437,349,NaN]	3	hSpCas9	negative selection	9827330
21799092	21799115	22	+	27869803	PATU8988S	viability after 35 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.7486970012594731	[647]	[228,648,NaN]	7	hSpCas9	negative selection	9827331
21805858	21805881	22	+	27869803	PATU8988S	viability after 35 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-0.9901871721961922	[569]	[144,85,NaN]	-7	hSpCas9	negative selection	9827332
21807772	21807795	22	+	27869803	PATU8988S	viability after 35 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.1719660077686022	[689]	[346,278,NaN]	2	hSpCas9	negative selection	9827333
21867341	21867364	22	-	27869803	PATU8988S	viability after 35 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.6118752426021714	[746]	[362,556,NaN]	6	hSpCas9	negative selection	9827334
21867352	21867375	22	+	27869803	PATU8988S	viability after 35 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	0.10877807319394728	[967]	[373,466,NaN]	1	hSpCas9	negative selection	9827335
21769297	21769320	22	+	27869803	PATU8988S	viability after 31 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	0.30168790113514876	[815]	[459,325,NaN]	4	hSpCas9	negative selection	9909779
21799092	21799115	22	+	27869803	PATU8988S	viability after 31 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	0.98659163039113	[647]	[273,814,NaN]	9	hSpCas9	negative selection	9909780
21805858	21805881	22	+	27869803	PATU8988S	viability after 31 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	-1.1644822436907838	[569]	[85,120,NaN]	-8	hSpCas9	negative selection	9909781
21807772	21807795	22	+	27869803	PATU8988S	viability after 31 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	0.3022943771933804	[689]	[278,415,NaN]	4	hSpCas9	negative selection	9909782
21867341	21867364	22	-	27869803	PATU8988S	viability after 31 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	0.5536583355579152	[746]	[445,425,NaN]	6	hSpCas9	negative selection	9909783
21867352	21867375	22	+	27869803	PATU8988S	viability after 31 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	0.08067862255838631	[967]	[328,508,NaN]	1	hSpCas9	negative selection	9909784
21769297	21769320	22	+	27869803	HPAFII	viability after 35 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	1.177466911173545	[475]	[489,606,NaN]	7	hSpCas9	negative selection	9992228
21799092	21799115	22	+	27869803	HPAFII	viability after 35 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	2.2004584439992176	[347]	[876,733,NaN]	9	hSpCas9	negative selection	9992229
21805858	21805881	22	+	27869803	HPAFII	viability after 35 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	0.7070614330783409	[249]	[247,159,NaN]	4	hSpCas9	negative selection	9992230
21807772	21807795	22	+	27869803	HPAFII	viability after 35 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	1.033092569755837	[411]	[431,420,NaN]	7	hSpCas9	negative selection	9992231
21867341	21867364	22	-	27869803	HPAFII	viability after 35 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.15938585914772946	[347]	[121,197,NaN]	-1	hSpCas9	negative selection	9992232
21867352	21867375	22	+	27869803	HPAFII	viability after 35 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	1.165993407931265	[337]	[525,223,NaN]	7	hSpCas9	negative selection	9992233
21769297	21769320	22	+	27869803	HPAFII	viability after 31 days	CTTGAATGGTGCTTCGGCGATGG	MAPK1	ENSG00000100030	1.06658459320795	[475]	[637,473,NaN]	7	hSpCas9	negative selection	10074677
21799092	21799115	22	+	27869803	HPAFII	viability after 31 days	CTGGATCTGCAACACGGGCCAGG	MAPK1	ENSG00000100030	1.6411321715641067	[347]	[813,385,NaN]	9	hSpCas9	negative selection	10074678
21805858	21805881	22	+	27869803	HPAFII	viability after 31 days	CACAGGTGGTGTTGAGCAGCAGG	MAPK1	ENSG00000100030	0.49094587874750584	[249]	[189,204,NaN]	3	hSpCas9	negative selection	10074679
21807772	21807795	22	+	27869803	HPAFII	viability after 31 days	CAGTAGGTCTGGTGCTCAAAGGG	MAPK1	ENSG00000100030	1.2055582475312723	[411]	[471,599,NaN]	8	hSpCas9	negative selection	10074680
21867341	21867364	22	-	27869803	HPAFII	viability after 31 days	CAACCTCTCGTACATCGGCGAGG	MAPK1	ENSG00000100030	-0.1497894146912236	[347]	[176,174,NaN]	-1	hSpCas9	negative selection	10074681
21867352	21867375	22	+	27869803	HPAFII	viability after 31 days	TACGAGAGGTTGGTGTAGCGCGG	MAPK1	ENSG00000100030	1.2629843343558076	[337]	[616,278,NaN]	8	hSpCas9	negative selection	10074682
21805844	21805867	22	+	28162770	P31FUJ	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-0.3942656271084947	[254]	[227]	-4	hSpCas9	negative selection	10189009
21867377	21867400	22	-	28162770	P31FUJ	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	0.7000835997270847	[10]	[20]	7	hSpCas9	negative selection	10189010
21867431	21867454	22	-	28162770	P31FUJ	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	0.3758392927762882	[140]	[214]	4	hSpCas9	negative selection	10189011
21807756	21807779	22	-	28162770	P31FUJ	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	0.2922888403293791	[204]	[294]	3	hSpCas9	negative selection	10189012
21772914	21772937	22	-	28162770	P31FUJ	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-0.2902304844634484	[204]	[196]	-3	hSpCas9	negative selection	10189013
21805873	21805896	22	+	28162770	P31FUJ	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-0.6871805953253904	[284]	[207]	-5	hSpCas9	negative selection	10189014
21805862	21805885	22	+	28162770	P31FUJ	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-0.2427518648219838	[290]	[288]	-2	hSpCas9	negative selection	10189015
21788682	21788705	22	+	28162770	P31FUJ	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-0.3004131105690562	[414]	[395]	-3	hSpCas9	negative selection	10189016
21772891	21772914	22	+	28162770	P31FUJ	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	0.42734779270099665	[80]	[127]	5	hSpCas9	negative selection	10189017
21772872	21772895	22	-	28162770	P31FUJ	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-0.26254954780843054	[97]	[95]	-2	hSpCas9	negative selection	10189018
21805844	21805867	22	+	28162770	TF1	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10358375
21867377	21867400	22	-	28162770	TF1	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10358376
21867431	21867454	22	-	28162770	TF1	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	NaN	[NaN]	[83]	1	hSpCas9	negative selection	10358377
21807756	21807779	22	-	28162770	TF1	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10358378
21772914	21772937	22	-	28162770	TF1	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10358379
21805873	21805896	22	+	28162770	TF1	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	NaN	[NaN]	[78]	1	hSpCas9	negative selection	10358380
21805862	21805885	22	+	28162770	TF1	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10358381
21788682	21788705	22	+	28162770	TF1	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10358382
21772891	21772914	22	+	28162770	TF1	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10358383
21772872	21772895	22	-	28162770	TF1	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10358384
21805844	21805867	22	+	28162770	SKM1	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-2.45759027181313	[86]	[27]	-9	hSpCas9	negative selection	10527741
21867377	21867400	22	-	28162770	SKM1	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	-3.4069641987431614	[5]	[0]	-9	hSpCas9	negative selection	10527742
21867431	21867454	22	-	28162770	SKM1	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	-0.37454272105078423	[32]	[44]	-3	hSpCas9	negative selection	10527743
21807756	21807779	22	-	28162770	SKM1	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	-3.2713090993855953	[70]	[12]	-9	hSpCas9	negative selection	10527744
21772914	21772937	22	-	28162770	SKM1	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-3.3849378924131632	[64]	[10]	-9	hSpCas9	negative selection	10527745
21805873	21805896	22	+	28162770	SKM1	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-3.0904905339479076	[105]	[21]	-9	hSpCas9	negative selection	10527746
21805862	21805885	22	+	28162770	SKM1	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-4.0950201924284215	[57]	[5]	-9	hSpCas9	negative selection	10527747
21788682	21788705	22	+	28162770	SKM1	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-2.055491828241784	[86]	[36]	-8	hSpCas9	negative selection	10527748
21772891	21772914	22	+	28162770	SKM1	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	-3.1439297929093675	[19]	[3]	-9	hSpCas9	negative selection	10527749
21772872	21772895	22	-	28162770	SKM1	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-2.2814333166593026	[21]	[7]	-8	hSpCas9	negative selection	10527750
21805844	21805867	22	+	28162770	SKM1	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-2.45759027181313	[86]	[27]	-9	hSpCas9	negative selection	10697107
21867377	21867400	22	-	28162770	SKM1	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	-3.4069641987431614	[5]	[0]	-9	hSpCas9	negative selection	10697108
21867431	21867454	22	-	28162770	SKM1	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	-0.37454272105078423	[32]	[44]	-3	hSpCas9	negative selection	10697109
21807756	21807779	22	-	28162770	SKM1	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	-3.2713090993855953	[70]	[12]	-9	hSpCas9	negative selection	10697110
21772914	21772937	22	-	28162770	SKM1	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-3.3849378924131632	[64]	[10]	-9	hSpCas9	negative selection	10697111
21805873	21805896	22	+	28162770	SKM1	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-3.0904905339479076	[105]	[21]	-9	hSpCas9	negative selection	10697112
21805862	21805885	22	+	28162770	SKM1	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-4.0950201924284215	[57]	[5]	-9	hSpCas9	negative selection	10697113
21788682	21788705	22	+	28162770	SKM1	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-2.055491828241784	[86]	[36]	-8	hSpCas9	negative selection	10697114
21772891	21772914	22	+	28162770	SKM1	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	-3.1439297929093675	[19]	[3]	-9	hSpCas9	negative selection	10697115
21772872	21772895	22	-	28162770	SKM1	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-2.2814333166593026	[21]	[7]	-8	hSpCas9	negative selection	10697116
21805844	21805867	22	+	28162770	PL21	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-1.3323554663377006	[323]	[55]	-7	hSpCas9	negative selection	10866473
21867377	21867400	22	-	28162770	PL21	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	1.685566441659562	[9]	[13]	9	hSpCas9	negative selection	10866474
21867431	21867454	22	-	28162770	PL21	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	-0.31267310047600094	[116]	[40]	-2	hSpCas9	negative selection	10866475
21807756	21807779	22	-	28162770	PL21	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	0.31224998081085725	[197]	[106]	2	hSpCas9	negative selection	10866476
21772914	21772937	22	-	28162770	PL21	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-0.3117594240421127	[230]	[80]	-2	hSpCas9	negative selection	10866477
21805873	21805896	22	+	28162770	PL21	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	0.213728679237275	[316]	[159]	2	hSpCas9	negative selection	10866478
21805862	21805885	22	+	28162770	PL21	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	0.2001396144893202	[147]	[73]	1	hSpCas9	negative selection	10866479
21788682	21788705	22	+	28162770	PL21	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-0.9203731928279142	[286]	[65]	-6	hSpCas9	negative selection	10866480
21772891	21772914	22	+	28162770	PL21	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	0.9106329972943352	[43]	[35]	7	hSpCas9	negative selection	10866481
21772872	21772895	22	-	28162770	PL21	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-2.5864567474014866	[68]	[4]	-9	hSpCas9	negative selection	10866482
21805844	21805867	22	+	28162770	P31FUJ	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-0.3942656271084947	[254]	[227]	-4	hSpCas9	negative selection	11035839
21867377	21867400	22	-	28162770	P31FUJ	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	0.7000835997270847	[10]	[20]	7	hSpCas9	negative selection	11035840
21867431	21867454	22	-	28162770	P31FUJ	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	0.3758392927762882	[140]	[214]	4	hSpCas9	negative selection	11035841
21807756	21807779	22	-	28162770	P31FUJ	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	0.2922888403293791	[204]	[294]	3	hSpCas9	negative selection	11035842
21772914	21772937	22	-	28162770	P31FUJ	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-0.2902304844634484	[204]	[196]	-3	hSpCas9	negative selection	11035843
21805873	21805896	22	+	28162770	P31FUJ	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-0.6871805953253904	[284]	[207]	-5	hSpCas9	negative selection	11035844
21805862	21805885	22	+	28162770	P31FUJ	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-0.2427518648219838	[290]	[288]	-2	hSpCas9	negative selection	11035845
21788682	21788705	22	+	28162770	P31FUJ	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-0.3004131105690562	[414]	[395]	-3	hSpCas9	negative selection	11035846
21772891	21772914	22	+	28162770	P31FUJ	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	0.42734779270099665	[80]	[127]	5	hSpCas9	negative selection	11035847
21772872	21772895	22	-	28162770	P31FUJ	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-0.26254954780843054	[97]	[95]	-2	hSpCas9	negative selection	11035848
21805844	21805867	22	+	28162770	OCIAML5	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-0.26936357732496585	[212]	[318]	-2	hSpCas9	negative selection	11205205
21867377	21867400	22	-	28162770	OCIAML5	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	-0.5041432674436903	[10]	[13]	-3	hSpCas9	negative selection	11205206
21867431	21867454	22	-	28162770	OCIAML5	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	-0.11510097669779092	[110]	[184]	-1	hSpCas9	negative selection	11205207
21807756	21807779	22	-	28162770	OCIAML5	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	-1.3195714900369764	[111]	[80]	-6	hSpCas9	negative selection	11205208
21772914	21772937	22	-	28162770	OCIAML5	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-0.6498777202507301	[112]	[129]	-4	hSpCas9	negative selection	11205209
21805873	21805896	22	+	28162770	OCIAML5	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-0.8114245863666512	[174]	[179]	-5	hSpCas9	negative selection	11205210
21805862	21805885	22	+	28162770	OCIAML5	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-1.3100562153273878	[124]	[90]	-6	hSpCas9	negative selection	11205211
21788682	21788705	22	+	28162770	OCIAML5	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-1.1139332752654565	[246]	[205]	-6	hSpCas9	negative selection	11205212
21772891	21772914	22	+	28162770	OCIAML5	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	-0.9382232146137115	[68]	[64]	-5	hSpCas9	negative selection	11205213
21772872	21772895	22	-	28162770	OCIAML5	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-0.5176475317934379	[45]	[57]	-4	hSpCas9	negative selection	11205214
21805844	21805867	22	+	28162770	EOL1	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-0.08359540173807967	[532]	[264]	0	hSpCas9	negative selection	11374571
21867377	21867400	22	-	28162770	EOL1	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	1.98867810899025	[21]	[45]	9	hSpCas9	negative selection	11374572
21867431	21867454	22	-	28162770	EOL1	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	0.16115405212668338	[201]	[118]	1	hSpCas9	negative selection	11374573
21807756	21807779	22	-	28162770	EOL1	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	-0.06571521706417915	[442]	[222]	0	hSpCas9	negative selection	11374574
21772914	21772937	22	-	28162770	EOL1	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-0.18011458980126543	[442]	[205]	-1	hSpCas9	negative selection	11374575
21805873	21805896	22	+	28162770	EOL1	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-0.28000584392822525	[642]	[278]	-2	hSpCas9	negative selection	11374576
21805862	21805885	22	+	28162770	EOL1	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-1.5202370711023612	[195]	[35]	-7	hSpCas9	negative selection	11374577
21788682	21788705	22	+	28162770	EOL1	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	0.49272568799612687	[316]	[234]	4	hSpCas9	negative selection	11374578
21772891	21772914	22	+	28162770	EOL1	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	0.567613226855259	[72]	[56]	5	hSpCas9	negative selection	11374579
21772872	21772895	22	-	28162770	EOL1	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	1.0753277237461436	[117]	[130]	8	hSpCas9	negative selection	11374580
21805844	21805867	22	+	28162770	MOLM13	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	1.4473767842188665	[424]	[837]	9	hSpCas9	negative selection	11543937
21867377	21867400	22	-	28162770	MOLM13	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	0.5458918935458521	[17]	[18]	4	hSpCas9	negative selection	11543938
21867431	21867454	22	-	28162770	MOLM13	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	2.576110782961716	[137]	[594]	9	hSpCas9	negative selection	11543939
21807756	21807779	22	-	28162770	MOLM13	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	1.0528518822657351	[259]	[389]	7	hSpCas9	negative selection	11543940
21772914	21772937	22	-	28162770	MOLM13	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	0.8713473619285393	[343]	[454]	6	hSpCas9	negative selection	11543941
21805873	21805896	22	+	28162770	MOLM13	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	0.7025081052142862	[469]	[552]	5	hSpCas9	negative selection	11543942
21805862	21805885	22	+	28162770	MOLM13	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	1.4711060942281216	[223]	[448]	9	hSpCas9	negative selection	11543943
21788682	21788705	22	+	28162770	MOLM13	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	0.3791451697144993	[351]	[330]	2	hSpCas9	negative selection	11543944
21772891	21772914	22	+	28162770	MOLM13	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	0.8371231912102977	[95]	[123]	6	hSpCas9	negative selection	11543945
21772872	21772895	22	-	28162770	MOLM13	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-0.8702793543499945	[133]	[52]	-5	hSpCas9	negative selection	11543946
21805844	21805867	22	+	28162770	HEL	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	0.683070926035575	[387]	[398]	6	hSpCas9	negative selection	11713303
21867377	21867400	22	-	28162770	HEL	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	-2.057700886140735	[25]	[3]	-8	hSpCas9	negative selection	11713304
21867431	21867454	22	-	28162770	HEL	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	-0.3401876546407018	[167]	[84]	-2	hSpCas9	negative selection	11713305
21807756	21807779	22	-	28162770	HEL	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	0.8448442391918192	[265]	[305]	7	hSpCas9	negative selection	11713306
21772914	21772937	22	-	28162770	HEL	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	0.12816565917059858	[289]	[202]	1	hSpCas9	negative selection	11713307
21805873	21805896	22	+	28162770	HEL	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	0.4043063993996412	[406]	[344]	3	hSpCas9	negative selection	11713308
21805862	21805885	22	+	28162770	HEL	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-0.32315331367937883	[208]	[106]	-2	hSpCas9	negative selection	11713309
21788682	21788705	22	+	28162770	HEL	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-0.17247820783021758	[321]	[182]	-1	hSpCas9	negative selection	11713310
21772891	21772914	22	+	28162770	HEL	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	-0.9576537092904049	[93]	[30]	-5	hSpCas9	negative selection	11713311
21772872	21772895	22	-	28162770	HEL	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-0.9004034930261722	[101]	[34]	-5	hSpCas9	negative selection	11713312
21805844	21805867	22	+	28162770	MV411	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	0.7442691412252663	[269]	[380]	6	hSpCas9	negative selection	11882669
21867377	21867400	22	-	28162770	MV411	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	1.1860370061186316	[11]	[22]	9	hSpCas9	negative selection	11882670
21867431	21867454	22	-	28162770	MV411	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	0.2060176234027945	[105]	[102]	1	hSpCas9	negative selection	11882671
21807756	21807779	22	-	28162770	MV411	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	0.15614171676322502	[211]	[198]	1	hSpCas9	negative selection	11882672
21772914	21772937	22	-	28162770	MV411	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-1.0279037505026316	[258]	[106]	-6	hSpCas9	negative selection	11882673
21805873	21805896	22	+	28162770	MV411	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-0.11291214333734911	[370]	[288]	-1	hSpCas9	negative selection	11882674
21805862	21805885	22	+	28162770	MV411	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-0.18866156402389822	[114]	[84]	-1	hSpCas9	negative selection	11882675
21788682	21788705	22	+	28162770	MV411	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-0.07173993308855253	[261]	[209]	0	hSpCas9	negative selection	11882676
21772891	21772914	22	+	28162770	MV411	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	-1.2306097460218688	[77]	[27]	-7	hSpCas9	negative selection	11882677
21772872	21772895	22	-	28162770	MV411	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-0.17525352103950387	[62]	[46]	-1	hSpCas9	negative selection	11882678
21805844	21805867	22	+	28162770	MONOMAC1	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-0.40984321956680353	[174]	[150]	-4	hSpCas9	negative selection	12052035
21867377	21867400	22	-	28162770	MONOMAC1	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	-0.8491135436392465	[10]	[6]	-6	hSpCas9	negative selection	12052036
21867431	21867454	22	-	28162770	MONOMAC1	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	-1.0975011735086393	[83]	[44]	-7	hSpCas9	negative selection	12052037
21807756	21807779	22	-	28162770	MONOMAC1	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	0.10635529639038119	[140]	[173]	1	hSpCas9	negative selection	12052038
21772914	21772937	22	-	28162770	MONOMAC1	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	0.08769262987355902	[164]	[200]	0	hSpCas9	negative selection	12052039
21805873	21805896	22	+	28162770	MONOMAC1	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	0.28184713424391616	[220]	[307]	3	hSpCas9	negative selection	12052040
21805862	21805885	22	+	28162770	MONOMAC1	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-0.014558795274156766	[88]	[100]	0	hSpCas9	negative selection	12052041
21788682	21788705	22	+	28162770	MONOMAC1	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-0.2768901547487682	[129]	[122]	-2	hSpCas9	negative selection	12052042
21772891	21772914	22	+	28162770	MONOMAC1	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	0.5059814151833149	[42]	[69]	5	hSpCas9	negative selection	12052043
21772872	21772895	22	-	28162770	MONOMAC1	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	0.5805707316039983	[27]	[47]	5	hSpCas9	negative selection	12052044
21805844	21805867	22	+	28162770	OCIAML2	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	-1.505395243402838	[41]	[81]	-7	hSpCas9	negative selection	12221401
21867377	21867400	22	-	28162770	OCIAML2	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	-3.0555923259633175	[2]	[1]	-9	hSpCas9	negative selection	12221402
21867431	21867454	22	-	28162770	OCIAML2	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	-0.5961607073260202	[26]	[98]	-4	hSpCas9	negative selection	12221403
21807756	21807779	22	-	28162770	OCIAML2	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	-3.038913584816687	[42]	[28]	-9	hSpCas9	negative selection	12221404
21772914	21772937	22	-	28162770	OCIAML2	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-3.5295235142957297	[49]	[23]	-9	hSpCas9	negative selection	12221405
21805873	21805896	22	+	28162770	OCIAML2	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-1.798684022926365	[58]	[93]	-8	hSpCas9	negative selection	12221406
21805862	21805885	22	+	28162770	OCIAML2	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-3.396629243798384	[18]	[9]	-9	hSpCas9	negative selection	12221407
21788682	21788705	22	+	28162770	OCIAML2	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-2.6722636864118114	[45]	[39]	-9	hSpCas9	negative selection	12221408
21772891	21772914	22	+	28162770	OCIAML2	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	-1.9401151085433814	[8]	[12]	-8	hSpCas9	negative selection	12221409
21772872	21772895	22	-	28162770	OCIAML2	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-3.4706298252421615	[7]	[3]	-9	hSpCas9	negative selection	12221410
21805844	21805867	22	+	28162770	OCIAML3	viability	GCTGACCTTGAGATCACAGGTGG	MAPK1	ENSG00000100030	0.43189422311859405	[68]	[280]	4	hSpCas9	negative selection	12390767
21867377	21867400	22	-	28162770	OCIAML3	viability	CCGCGGGCAGGTGTTCGACGTGG	MAPK1	ENSG00000100030	0.3128829552843553	[3]	[14]	3	hSpCas9	negative selection	12390768
21867431	21867454	22	-	28162770	OCIAML3	viability	CCCGGCAGCCAACATGGCGGCGG	MAPK1	ENSG00000100030	0.3028988667117334	[28]	[107]	3	hSpCas9	negative selection	12390769
21807756	21807779	22	-	28162770	OCIAML3	viability	CCTACTGCCAGAGAACCCTGAGG	MAPK1	ENSG00000100030	-1.7369655941662063	[52]	[47]	-8	hSpCas9	negative selection	12390770
21772914	21772937	22	-	28162770	OCIAML3	viability	GATTGAAGTAGAACAGGCTCTGG	MAPK1	ENSG00000100030	-1.2154960170704334	[49]	[64]	-7	hSpCas9	negative selection	12390771
21805873	21805896	22	+	28162770	OCIAML3	viability	GCAGCAGGTTGGAAGGCTTGAGG	MAPK1	ENSG00000100030	-1.4603292050921937	[102]	[112]	-7	hSpCas9	negative selection	12390772
21805862	21805885	22	+	28162770	OCIAML3	viability	GGTGGTGTTGAGCAGCAGGTTGG	MAPK1	ENSG00000100030	-1.1789701410453195	[41]	[55]	-7	hSpCas9	negative selection	12390773
21788682	21788705	22	+	28162770	OCIAML3	viability	CGGGAACCTTACCCAAAATGTGG	MAPK1	ENSG00000100030	-0.3045010231291782	[62]	[153]	-2	hSpCas9	negative selection	12390774
21772891	21772914	22	+	28162770	OCIAML3	viability	ATACTGCTCCAGATATGGGTGGG	MAPK1	ENSG00000100030	-3.0414666172953844	[29]	[10]	-9	hSpCas9	negative selection	12390775
21772872	21772895	22	-	28162770	OCIAML3	viability	GTATTACGACCCGAGTGACGAGG	MAPK1	ENSG00000100030	-2.672010152325436	[18]	[8]	-9	hSpCas9	negative selection	12390776