Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5597
• Symbol:MAPK6
• Description:mitogen-activated protein kinase 6

DataSource: http://genomecrispr.dkfz.de/#!/results/MAPK6

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
51966354	51966377	15	-	26472758	Jiyoye	viability	GGAGATGACAGTGAGGACGAGGG	MAPK6	ENSG00000069956	-0.5113970191502805	[154]	[81]	-4	hSpCas9	negative selection	89935
51966411	51966434	15	-	26472758	Jiyoye	viability	GAAAGTGATCAGGATGAAAGAGG	MAPK6	ENSG00000069956	-0.45736120119900786	[192]	[105]	-3	hSpCas9	negative selection	89936
51966336	51966359	15	-	26472758	Jiyoye	viability	GAGGGAGCTTCACATCATAGTGG	MAPK6	ENSG00000069956	-0.7878406008992693	[173]	[75]	-5	hSpCas9	negative selection	89937
51966186	51966209	15	-	26472758	Jiyoye	viability	GAAGGTCATAGATCGGATGGAGG	MAPK6	ENSG00000069956	-1.3773516110974695	[626]	[181]	-7	hSpCas9	negative selection	89939
51960649	51960672	15	-	26472758	Jiyoye	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-1.237596514450586	[196]	[62]	-7	hSpCas9	negative selection	89940
51958764	51958787	15	-	26472758	Jiyoye	viability	GAAGAAATGCTGGATGAAGAAGG	MAPK6	ENSG00000069956	-1.8558590243279203	[167]	[34]	-8	hSpCas9	negative selection	89941
51954492	51954515	15	-	26472758	Jiyoye	viability	GCAATGCTCGGATAGTCAAGTGG	MAPK6	ENSG00000069956	-1.2510361012459215	[201]	[63]	-7	hSpCas9	negative selection	89942
51971730	51971753	15	-	26472758	Jiyoye	viability	AGCGATAATGGCGGATATGGAGG	MAPK6	ENSG00000069956	-1.888280502020298	[53]	[10]	-8	hSpCas9	negative selection	89944
52046724	52046747	15	+	26472758	Jiyoye	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	1.1142394899582178	[116]	[190]	7	hSpCas9	negative selection	96314
52046533	52046556	15	-	26472758	Jiyoye	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	-0.5298933627676701	[313]	[163]	-4	hSpCas9	negative selection	96315
52046524	52046547	15	+	26472758	Jiyoye	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.8752201304478785	[166]	[230]	6	hSpCas9	negative selection	96316
52046701	52046724	15	+	26472758	Jiyoye	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	-0.7096382834768766	[179]	[82]	-5	hSpCas9	negative selection	96317
52046956	52046979	15	+	26472758	Jiyoye	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	-0.04533682319163346	[155]	[113]	0	hSpCas9	negative selection	96318
51966354	51966377	15	-	26472758	KBM7	viability	GGAGATGACAGTGAGGACGAGGG	MAPK6	ENSG00000069956	0.058231803367300605	[1031,822]	[506,400]	0	hSpCas9	negative selection	281053
51966411	51966434	15	-	26472758	KBM7	viability	GAAAGTGATCAGGATGAAAGAGG	MAPK6	ENSG00000069956	0.11651062906054144	[678,913]	[279,533]	1	hSpCas9	negative selection	281054
51966336	51966359	15	-	26472758	KBM7	viability	GAGGGAGCTTCACATCATAGTGG	MAPK6	ENSG00000069956	0.5491005934335861	[572,449]	[664,66]	6	hSpCas9	negative selection	281055
51966186	51966209	15	-	26472758	KBM7	viability	GAAGGTCATAGATCGGATGGAGG	MAPK6	ENSG00000069956	-0.7532534853725485	[1975,1254]	[403,476]	-6	hSpCas9	negative selection	281057
51960649	51960672	15	-	26472758	KBM7	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.33018708995047974	[1009,894]	[378,334]	-3	hSpCas9	negative selection	281058
51958764	51958787	15	-	26472758	KBM7	viability	GAAGAAATGCTGGATGAAGAAGG	MAPK6	ENSG00000069956	-0.6567731673321466	[383,352]	[138,83]	-5	hSpCas9	negative selection	281059
51954492	51954515	15	-	26472758	KBM7	viability	GCAATGCTCGGATAGTCAAGTGG	MAPK6	ENSG00000069956	-2.3246659451721112	[806,858]	[53,100]	-9	hSpCas9	negative selection	281060
51971730	51971753	15	-	26472758	KBM7	viability	AGCGATAATGGCGGATATGGAGG	MAPK6	ENSG00000069956	0.16396674471406492	[115,111]	[17,97]	1	hSpCas9	negative selection	281062
52046724	52046747	15	+	26472758	KBM7	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.3529898136917501	[738,588]	[403,388]	4	hSpCas9	negative selection	287432
52046533	52046556	15	-	26472758	KBM7	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.09285036073508957	[973,792]	[571,322]	0	hSpCas9	negative selection	287433
52046524	52046547	15	+	26472758	KBM7	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	-0.16976239778765773	[879,511]	[369,207]	-2	hSpCas9	negative selection	287434
52046701	52046724	15	+	26472758	KBM7	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	0.6000332139516827	[206,275]	[194,157]	6	hSpCas9	negative selection	287435
52046956	52046979	15	+	26472758	KBM7	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	0.14014026552193598	[622,697]	[262,419]	1	hSpCas9	negative selection	287436
51966354	51966377	15	-	26472758	Raji	viability	GGAGATGACAGTGAGGACGAGGG	MAPK6	ENSG00000069956	-0.38550338044917765	[348]	[61]	-3	hSpCas9	negative selection	472171
51966411	51966434	15	-	26472758	Raji	viability	GAAAGTGATCAGGATGAAAGAGG	MAPK6	ENSG00000069956	-0.2442154261901056	[392]	[76]	-2	hSpCas9	negative selection	472172
51966336	51966359	15	-	26472758	Raji	viability	GAGGGAGCTTCACATCATAGTGG	MAPK6	ENSG00000069956	-1.5999755967072833	[208]	[15]	-8	hSpCas9	negative selection	472173
51966186	51966209	15	-	26472758	Raji	viability	GAAGGTCATAGATCGGATGGAGG	MAPK6	ENSG00000069956	-1.0067874845457117	[735]	[84]	-6	hSpCas9	negative selection	472175
51960649	51960672	15	-	26472758	Raji	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.31846586157267176	[310]	[89]	3	hSpCas9	negative selection	472176
51958764	51958787	15	-	26472758	Raji	viability	GAAGAAATGCTGGATGAAGAAGG	MAPK6	ENSG00000069956	-3.1872372135180274	[156]	[3]	-9	hSpCas9	negative selection	472177
51954492	51954515	15	-	26472758	Raji	viability	GCAATGCTCGGATAGTCAAGTGG	MAPK6	ENSG00000069956	-1.8061249389994267	[436]	[28]	-8	hSpCas9	negative selection	472178
51971730	51971753	15	-	26472758	Raji	viability	AGCGATAATGGCGGATATGGAGG	MAPK6	ENSG00000069956	-2.6652059685233285	[81]	[2]	-9	hSpCas9	negative selection	472180
52046724	52046747	15	+	26472758	Raji	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.14743036365522577	[419]	[87]	-1	hSpCas9	negative selection	478550
52046533	52046556	15	-	26472758	Raji	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.3509405667080896	[347]	[102]	3	hSpCas9	negative selection	478551
52046524	52046547	15	+	26472758	Raji	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.4813937663923887	[320]	[103]	4	hSpCas9	negative selection	478552
52046701	52046724	15	+	26472758	Raji	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	0.2298675418985947	[157]	[42]	2	hSpCas9	negative selection	478553
52046956	52046979	15	+	26472758	Raji	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	-0.05015774161288028	[289]	[64]	0	hSpCas9	negative selection	478554
51966354	51966377	15	-	26472758	K562	viability	GGAGATGACAGTGAGGACGAGGG	MAPK6	ENSG00000069956	-2.680105542457687	[781]	[102]	-8	hSpCas9	negative selection	663289
51966411	51966434	15	-	26472758	K562	viability	GAAAGTGATCAGGATGAAAGAGG	MAPK6	ENSG00000069956	-0.6599518759635562	[714]	[381]	-4	hSpCas9	negative selection	663290
51966336	51966359	15	-	26472758	K562	viability	GAGGGAGCTTCACATCATAGTGG	MAPK6	ENSG00000069956	-1.775325207631968	[514]	[126]	-7	hSpCas9	negative selection	663291
51966186	51966209	15	-	26472758	K562	viability	GAAGGTCATAGATCGGATGGAGG	MAPK6	ENSG00000069956	-1.2638288069138963	[1592]	[559]	-6	hSpCas9	negative selection	663293
51960649	51960672	15	-	26472758	K562	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.6243367390553004	[713]	[390]	-4	hSpCas9	negative selection	663294
51958764	51958787	15	-	26472758	K562	viability	GAAGAAATGCTGGATGAAGAAGG	MAPK6	ENSG00000069956	-1.4523577763840603	[294]	[90]	-6	hSpCas9	negative selection	663295
51954492	51954515	15	-	26472758	K562	viability	GCAATGCTCGGATAGTCAAGTGG	MAPK6	ENSG00000069956	-2.892572384413783	[562]	[63]	-8	hSpCas9	negative selection	663296
51971730	51971753	15	-	26472758	K562	viability	AGCGATAATGGCGGATATGGAGG	MAPK6	ENSG00000069956	-3.364390515009077	[121]	[9]	-8	hSpCas9	negative selection	663298
52046724	52046747	15	+	26472758	K562	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.46845900188437695	[499]	[583]	4	hSpCas9	negative selection	669668
52046533	52046556	15	-	26472758	K562	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.12869102061294663	[479]	[442]	0	hSpCas9	negative selection	669669
52046524	52046547	15	+	26472758	K562	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.3831707976136408	[524]	[577]	3	hSpCas9	negative selection	669670
52046701	52046724	15	+	26472758	K562	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	-0.47017905347130495	[319]	[194]	-3	hSpCas9	negative selection	669671
52046956	52046979	15	+	26472758	K562	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	-0.06781286861055108	[518]	[417]	0	hSpCas9	negative selection	669672
51966385	51966408	15	-	24336569	HL60	viability	TTCAGGACAACCAAGTAATAAGG	MAPK6	ENSG00000069956	1.3430337278990137	[170]	[917]	8	hSpCas9	negative selection	2274571
51966402	51966425	15	-	24336569	HL60	viability	CAGGATGAAAGAGGTGATTCAGG	MAPK6	ENSG00000069956	0.034332898470480155	[693]	[1503]	0	hSpCas9	negative selection	2274572
51966411	51966434	15	-	24336569	HL60	viability	GAAAGTGATCAGGATGAAAGAGG	MAPK6	ENSG00000069956	0.12754101424582165	[695]	[1608]	1	hSpCas9	negative selection	2274573
51966422	51966445	15	+	24336569	HL60	viability	CTGATCACTTTCACTTCCAGAGG	MAPK6	ENSG00000069956	0.012230694332957648	[923]	[1971]	0	hSpCas9	negative selection	2274574
51966437	51966460	15	+	24336569	HL60	viability	TCCAGAGGCATTACTGCCAGAGG	MAPK6	ENSG00000069956	0.0392057860113621	[383]	[834]	0	hSpCas9	negative selection	2274575
51966453	51966476	15	-	24336569	HL60	viability	GATCAAGAGAATGCTGCCTCTGG	MAPK6	ENSG00000069956	-1.0311590187808308	[309]	[320]	-7	hSpCas9	negative selection	2274576
51971684	51971707	15	-	24336569	HL60	viability	AGCGAAGCTGAGCGTAAAGGTGG	MAPK6	ENSG00000069956	-1.4272389374706262	[609]	[479]	-8	hSpCas9	negative selection	2274577
51971689	51971712	15	+	24336569	HL60	viability	TTTACGCTCAGCTTCGCTGTCGG	MAPK6	ENSG00000069956	-0.9912662916573178	[495]	[527]	-7	hSpCas9	negative selection	2274578
51971719	51971742	15	-	24336569	HL60	viability	CGGATATGGAGGATCTCTTCGGG	MAPK6	ENSG00000069956	0.6858015338131969	[244]	[833]	6	hSpCas9	negative selection	2274579
51971730	51971753	15	-	24336569	HL60	viability	AGCGATAATGGCGGATATGGAGG	MAPK6	ENSG00000069956	-0.9174076972757221	[738]	[827]	-7	hSpCas9	negative selection	2274580
52046502	52046525	15	+	24336569	HL60	viability	TGATCTGGGTTCTAGGTATATGG	MAPK6	ENSG00000069956	-0.1236923360181936	[519]	[1009]	-1	hSpCas9	negative selection	2276140
52046533	52046556	15	-	24336569	HL60	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.0492395910156974	[463]	[1015]	0	hSpCas9	negative selection	2276141
52046692	52046715	15	+	24336569	HL60	viability	GTGAAAGTGTTTGAGATTCTTGG	MAPK6	ENSG00000069956	1.1897707863067581	[306]	[1481]	8	hSpCas9	negative selection	2276142
52046701	52046724	15	+	24336569	HL60	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	1.2527772556973176	[139]	[705]	8	hSpCas9	negative selection	2276143
52046716	52046739	15	-	24336569	HL60	viability	TCTGTTAATTGGCTTCCACTGGG	MAPK6	ENSG00000069956	-0.3748409927573255	[1181]	[1928]	-3	hSpCas9	negative selection	2276144
52046724	52046747	15	+	24336569	HL60	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.2939032532199264	[529]	[1374]	2	hSpCas9	negative selection	2276145
52046934	52046957	15	+	24336569	HL60	viability	TTTCATTAATACGGAAGACTTGG	MAPK6	ENSG00000069956	-0.11789772977646429	[801]	[1563]	-1	hSpCas9	negative selection	2276146
52046956	52046979	15	+	24336569	HL60	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	-0.10580008524015039	[1105]	[2174]	-1	hSpCas9	negative selection	2276147
52046998	52047021	15	-	24336569	HL60	viability	CATACCTTATGGGAATAATGAGG	MAPK6	ENSG00000069956	1.0968731406296164	[246]	[1117]	8	hSpCas9	negative selection	2276148
52047008	52047031	15	-	24336569	HL60	viability	GCTTTCTATACATACCTTATGGG	MAPK6	ENSG00000069956	-0.05984128892910112	[297]	[604]	0	hSpCas9	negative selection	2276149
51966385	51966408	15	-	24336569	KBM7	viability	TTCAGGACAACCAAGTAATAAGG	MAPK6	ENSG00000069956	1.0261602587722982	[300]	[1671]	8	hSpCas9	negative selection	2341748
51966402	51966425	15	-	24336569	KBM7	viability	CAGGATGAAAGAGGTGATTCAGG	MAPK6	ENSG00000069956	-0.0780824811802236	[530]	[1371]	0	hSpCas9	negative selection	2341749
51966411	51966434	15	-	24336569	KBM7	viability	GAAAGTGATCAGGATGAAAGAGG	MAPK6	ENSG00000069956	0.18172592905279306	[565]	[1750]	1	hSpCas9	negative selection	2341750
51966422	51966445	15	+	24336569	KBM7	viability	CTGATCACTTTCACTTCCAGAGG	MAPK6	ENSG00000069956	0.7053879430669473	[560]	[2494]	6	hSpCas9	negative selection	2341751
51966437	51966460	15	+	24336569	KBM7	viability	TCCAGAGGCATTACTGCCAGAGG	MAPK6	ENSG00000069956	-0.48439186216660957	[257]	[502]	-4	hSpCas9	negative selection	2341752
51966453	51966476	15	-	24336569	KBM7	viability	GATCAAGAGAATGCTGCCTCTGG	MAPK6	ENSG00000069956	-1.8582115167077256	[326]	[245]	-8	hSpCas9	negative selection	2341753
51971684	51971707	15	-	24336569	KBM7	viability	AGCGAAGCTGAGCGTAAAGGTGG	MAPK6	ENSG00000069956	-3.2321194893743193	[595]	[172]	-9	hSpCas9	negative selection	2341754
51971689	51971712	15	+	24336569	KBM7	viability	TTTACGCTCAGCTTCGCTGTCGG	MAPK6	ENSG00000069956	-1.1263930379292935	[388]	[485]	-7	hSpCas9	negative selection	2341755
51971719	51971742	15	-	24336569	KBM7	viability	CGGATATGGAGGATCTCTTCGGG	MAPK6	ENSG00000069956	-1.8895837434279956	[359]	[264]	-8	hSpCas9	negative selection	2341756
51971730	51971753	15	-	24336569	KBM7	viability	AGCGATAATGGCGGATATGGAGG	MAPK6	ENSG00000069956	0.042746430034198424	[314]	[884]	0	hSpCas9	negative selection	2341757
52046502	52046525	15	+	24336569	KBM7	viability	TGATCTGGGTTCTAGGTATATGG	MAPK6	ENSG00000069956	1.3638225585714236	[355]	[2498]	9	hSpCas9	negative selection	2343317
52046533	52046556	15	-	24336569	KBM7	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.3287696688975065	[429]	[1472]	3	hSpCas9	negative selection	2343318
52046692	52046715	15	+	24336569	KBM7	viability	GTGAAAGTGTTTGAGATTCTTGG	MAPK6	ENSG00000069956	0.12469198522865188	[646]	[1923]	1	hSpCas9	negative selection	2343319
52046701	52046724	15	+	24336569	KBM7	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	0.07257500854417542	[257]	[739]	0	hSpCas9	negative selection	2343320
52046716	52046739	15	-	24336569	KBM7	viability	TCTGTTAATTGGCTTCCACTGGG	MAPK6	ENSG00000069956	0.030468100255761854	[811]	[2261]	0	hSpCas9	negative selection	2343321
52046724	52046747	15	+	24336569	KBM7	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.628442044476083	[330]	[583]	-5	hSpCas9	negative selection	2343322
52046934	52046957	15	+	24336569	KBM7	viability	TTTCATTAATACGGAAGACTTGG	MAPK6	ENSG00000069956	0.6832842788790164	[781]	[3424]	6	hSpCas9	negative selection	2343323
52046956	52046979	15	+	24336569	KBM7	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	0.1689646666576139	[737]	[2262]	1	hSpCas9	negative selection	2343324
52046998	52047021	15	-	24336569	KBM7	viability	CATACCTTATGGGAATAATGAGG	MAPK6	ENSG00000069956	0.0658922618013037	[261]	[747]	0	hSpCas9	negative selection	2343325
52047008	52047031	15	-	24336569	KBM7	viability	GCTTTCTATACATACCTTATGGG	MAPK6	ENSG00000069956	-1.4923175113141671	[392]	[380]	-7	hSpCas9	negative selection	2343326
52043572	52043595	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCGCGCCTGG	MAPK6	ENSG00000069956	-0.8581528486253212	[26,35]	[2,3]	-5	dCas9-VP64	positive selection	2392153
52025566	52025589	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGAGGCGGGCGGATCACGAGG	MAPK6	ENSG00000069956	3.028184953541963	[9,0]	[15,2]	8	dCas9-VP64	positive selection	2413694
52000772	52000795	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCTCTCTGTCGCCCAAG	MAPK6	ENSG00000069956	1.6026852076585545	[0,1]	[0,0]	6	dCas9-VP64	positive selection	2429621
52019099	52019122	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAATTTCCAGCGCCCGTGACTGG	MAPK6	ENSG00000069956	0.010989659437370514	[127,185]	[10,58]	0	dCas9-VP64	positive selection	2431033
51973382	51973405	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCACTGCGCTCCAGCCTAGG	MAPK6	ENSG00000069956	-0.692868363357688	[238,335]	[46,29]	-4	dCas9-VP64	positive selection	2441016
52048489	52048512	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTCTGTAATTCCAGCTACTCGG	MAPK6	ENSG00000069956	-0.34157194181705264	[352,113]	[62,14]	-1	dCas9-VP64	positive selection	2443519
52051621	52051644	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGGCTGCAG	MAPK6	ENSG00000069956	0.17430442440476024	[13,29]	[6,2]	0	dCas9-VP64	positive selection	2446151
52037085	52037108	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGGCTGGTCTTGAACTCCCGG	MAPK6	ENSG00000069956	1.1112377139242877	[89,193]	[7,132]	4	dCas9-VP64	positive selection	2451693
52037067	52037090	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGAGGATCACTTGAGGCCGGG	MAPK6	ENSG00000069956	3.7396651611807004	[3,72]	[11,226]	9	dCas9-VP64	positive selection	2451791
52026405	52026428	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTTGGGAGGCTGCAG	MAPK6	ENSG00000069956	1.7381005027272516	[41,48]	[11,55]	6	dCas9-VP64	positive selection	2458103
51971925	51971948	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGATATTGACGAAATGGCCGGG	MAPK6	ENSG00000069956	0.6545549463823435	[129,19]	[20,29]	3	dCas9-VP64	positive selection	2464749
51971949	51971972	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TATTTGCCAGGATTCTTACCAGG	MAPK6	ENSG00000069956	-1.0927107841720203	[302,932]	[31,98]	-6	dCas9-VP64	positive selection	2464750
51971894	51971917	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTTCTCGCCTGGGTATGCATGG	MAPK6	ENSG00000069956	-0.027431163947046144	[241,114]	[21,54]	0	dCas9-VP64	positive selection	2464751
51961466	51961489	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TACTGCAACCTCTGCCTCCCGAG	MAPK6	ENSG00000069956	-0.5062023598928189	[190,459]	[52,47]	-2	dCas9-VP64	positive selection	2470978
52043572	52043595	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCGCGCCTGG	MAPK6	ENSG00000069956	-0.2201981089703296	[184,135]	[60,29]	-2	dCas9-VP64	positive selection	2487408
52025566	52025589	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGAGGCGGGCGGATCACGAGG	MAPK6	ENSG00000069956	1.1893121523925974	[28,6]	[25,1]	7	dCas9-VP64	positive selection	2508949
52000772	52000795	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCTCTCTGTCGCCCAAG	MAPK6	ENSG00000069956	0.31611073697098746	[6,38]	[2,13]	2	dCas9-VP64	positive selection	2524876
52019099	52019122	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAATTTCCAGCGCCCGTGACTGG	MAPK6	ENSG00000069956	-0.7544140218396068	[265,137]	[36,40]	-7	dCas9-VP64	positive selection	2526288
51973382	51973405	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCACTGCGCTCCAGCCTAGG	MAPK6	ENSG00000069956	0.15562510186866851	[37,63]	[19,15]	1	dCas9-VP64	positive selection	2536271
52048489	52048512	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTCTGTAATTCCAGCTACTCGG	MAPK6	ENSG00000069956	0.39117051359977273	[124,354]	[51,147]	3	dCas9-VP64	positive selection	2538774
52051621	52051644	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGGCTGCAG	MAPK6	ENSG00000069956	-0.20184825873935663	[30,89]	[7,24]	-2	dCas9-VP64	positive selection	2541406
52037085	52037108	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGGCTGGTCTTGAACTCCCGG	MAPK6	ENSG00000069956	-0.05379639634842043	[67,143]	[20,43]	0	dCas9-VP64	positive selection	2546948
52037067	52037090	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGAGGATCACTTGAGGCCGGG	MAPK6	ENSG00000069956	0.5989374680558959	[87,40]	[52,11]	4	dCas9-VP64	positive selection	2547046
52026405	52026428	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTTGGGAGGCTGCAG	MAPK6	ENSG00000069956	0.27268558780642654	[105,40]	[39,17]	2	dCas9-VP64	positive selection	2553358
51971925	51971948	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGATATTGACGAAATGGCCGGG	MAPK6	ENSG00000069956	-0.40318024096154825	[285,108]	[85,13]	-4	dCas9-VP64	positive selection	2560004
51971949	51971972	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TATTTGCCAGGATTCTTACCAGG	MAPK6	ENSG00000069956	-0.21988050415933702	[229,172]	[58,53]	-2	dCas9-VP64	positive selection	2560005
51971894	51971917	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTTCTCGCCTGGGTATGCATGG	MAPK6	ENSG00000069956	-0.2992500337573249	[144,230]	[44,53]	-3	dCas9-VP64	positive selection	2560006
51961466	51961489	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TACTGCAACCTCTGCCTCCCGAG	MAPK6	ENSG00000069956	0.6085406430083108	[122,167]	[85,58]	4	dCas9-VP64	positive selection	2566233
52046533	52046556	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.13282118622188446	[3,3]	[3,2]	3	hSpCas9	positive selection	3001270
52046716	52046739	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGTTAATTGGCTTCCACTGGG	MAPK6	ENSG00000069956	-0.16152751544046673	[5,5]	[4,3]	-2	hSpCas9	positive selection	3001271
52050035	52050058	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAGGAGAAAGTAAAAGACGTGG	MAPK6	ENSG00000069956	-0.40261368948801585	[3,3]	[2,2]	-5	hSpCas9	positive selection	3001272
52046533	52046556	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	-0.3110702518626132	[3,3]	[3,0]	-5	hSpCas9	positive selection	3069128
52046716	52046739	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGTTAATTGGCTTCCACTGGG	MAPK6	ENSG00000069956	0.20015373952331927	[5,5]	[4,3]	3	hSpCas9	positive selection	3069129
52050035	52050058	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAGGAGAAAGTAAAAGACGTGG	MAPK6	ENSG00000069956	0.12197700283949478	[3,3]	[2,2]	2	hSpCas9	positive selection	3069130
52049987	52050010		+	24336571	A375	resistance to PLX after 7 days	TTATAGGGTCATCTTTCTGAAGG	MAPK6	ENSG00000069956	0.0782520903563586	[9,8]	[11,7]	2	hSpCas9	positive selection	3126404
52049987	52050010		+	24336571	A375	resistance to PLX after 14 days	TTATAGGGTCATCTTTCTGAAGG	MAPK6	ENSG00000069956	-0.6047437516117385	[15,8]	[2,3]	-7	hSpCas9	positive selection	3184197
52049987	52050010		+	24336571	A375	viability after 7 days	TTATAGGGTCATCTTTCTGAAGG	MAPK6	ENSG00000069956	-0.4665843126129182	[13]	[9,8]	-6	hSpCas9	negative selection	3241990
52049987	52050010		+	24336571	A375	viability after 14 days	TTATAGGGTCATCTTTCTGAAGG	MAPK6	ENSG00000069956	-0.054859189119311424	[13]	[15,8]	0	hSpCas9	negative selection	3299783
52046533	52046556	15	-	26780180	HT29	viability (Avana library 4 designs)	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	1.39369098803926	[]	[]	5	hSpCas9	negative selection	3438916
52046716	52046739	15	-	26780180	HT29	viability (Avana library 4 designs)	TCTGTTAATTGGCTTCCACTGGG	MAPK6	ENSG00000069956	1.91539861037042	[]	[]	7	hSpCas9	negative selection	3438917
52050035	52050058	15	-	26780180	HT29	viability (Avana library 4 designs)	TTAGGAGAAAGTAAAAGACGTGG	MAPK6	ENSG00000069956	4.13860011454187	[]	[]	9	hSpCas9	negative selection	3438918
52046533	52046556	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	-5.54891944768446	[]	[]	-6	hSpCas9	negative selection	3528403
52050035	52050058	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAGGAGAAAGTAAAAGACGTGG	MAPK6	ENSG00000069956	-7.26217730515189	[]	[]	-6	hSpCas9	negative selection	3528404
52046716	52046739	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGTTAATTGGCTTCCACTGGG	MAPK6	ENSG00000069956	-3.59602050765967	[]	[]	-4	hSpCas9	negative selection	3528405
52046855	52046878	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCATGTATCAGCTGCTACGGGGG	MAPK6	ENSG00000069956	-3.35640383710995	[]	[]	-4	hSpCas9	negative selection	3528406
52046518	52046541	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATATGGACTTAAAACCATTGGG	MAPK6	ENSG00000069956	-17.0132825643585	[]	[]	-9	hSpCas9	negative selection	3528407
52046533	52046556	15	-	26780180	A375	viability (Avana lentiGuide)	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	-2.73204772128058	[]	[]	-5	hSpCas9	negative selection	3637062
52050035	52050058	15	-	26780180	A375	viability (Avana lentiGuide)	TTAGGAGAAAGTAAAAGACGTGG	MAPK6	ENSG00000069956	0.900926354906322	[]	[]	1	hSpCas9	negative selection	3637063
52046716	52046739	15	-	26780180	A375	viability (Avana lentiGuide)	TCTGTTAATTGGCTTCCACTGGG	MAPK6	ENSG00000069956	3.07255197631741	[]	[]	3	hSpCas9	negative selection	3637064
52046855	52046878	15	+	26780180	A375	viability (Avana lentiGuide)	TCATGTATCAGCTGCTACGGGGG	MAPK6	ENSG00000069956	26.5901309221317	[]	[]	9	hSpCas9	negative selection	3637065
52046518	52046541	15	+	26780180	A375	viability (Avana lentiGuide)	TATATGGACTTAAAACCATTGGG	MAPK6	ENSG00000069956	-4.13576432366886	[]	[]	-7	hSpCas9	negative selection	3637066
52046533	52046556	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	-0.5566580172219772	[4]	[3,1]	-7	hSpCas9	positive selection	3745721
52050035	52050058	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAGGAGAAAGTAAAAGACGTGG	MAPK6	ENSG00000069956	-0.6752422020557567	[8]	[5,3]	-7	hSpCas9	positive selection	3745722
52046716	52046739	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGTTAATTGGCTTCCACTGGG	MAPK6	ENSG00000069956	-0.07385089671897496	[6]	[5,5]	-1	hSpCas9	positive selection	3745723
52046855	52046878	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATGTATCAGCTGCTACGGGGG	MAPK6	ENSG00000069956	-0.9175978304668597	[5]	[2,2]	-8	hSpCas9	positive selection	3745724
52046518	52046541	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATATGGACTTAAAACCATTGGG	MAPK6	ENSG00000069956	-0.7261579842923496	[9]	[4,4]	-8	hSpCas9	positive selection	3745725
52046533	52046556	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.3954655258976734	[5]	[6,5]	9	hSpCas9	positive selection	3854328
52050035	52050058	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAGGAGAAAGTAAAAGACGTGG	MAPK6	ENSG00000069956	-0.19205820440246502	[5]	[3,4]	-3	hSpCas9	positive selection	3854329
52046716	52046739	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGTTAATTGGCTTCCACTGGG	MAPK6	ENSG00000069956	0.18006922744959797	[7]	[6,7]	4	hSpCas9	positive selection	3854330
52046855	52046878	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATGTATCAGCTGCTACGGGGG	MAPK6	ENSG00000069956	-0.3703963040514352	[5]	[2,3]	-5	hSpCas9	positive selection	3854331
52046518	52046541	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATATGGACTTAAAACCATTGGG	MAPK6	ENSG00000069956	0.09792542013631632	[5]	[5,4]	2	hSpCas9	positive selection	3854332
51962481	51962504	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCCTTATAGAATCTGCAAGAGG	MAPK6	ENSG00000069956	-0.5409226282240683	[2]	[0,0]	-9	hSpCas9	positive selection	4148494
51962413	51962436	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATTGCATCTGATTCAGAAGCGG	MAPK6	ENSG00000069956	-0.19471397587519623	[1]	[0,0]	-4	hSpCas9	positive selection	4148495
51960631	51960654	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.678470933410004	[4]	[2,7]	9	hSpCas9	positive selection	4148496
52049987	52050010	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTATAGGGTCATCTTTCTGAAGG	MAPK6	ENSG00000069956	-0.3818798451080062	[3]	[1,1]	-7	hSpCas9	positive selection	4150624
51962481	51962504	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCCTTATAGAATCTGCAAGAGG	MAPK6	ENSG00000069956	0.9010229331857097	[2]	[1,0,0,3]	6	hSpCas9	positive selection	4212516
51962413	51962436	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATTGCATCTGATTCAGAAGCGG	MAPK6	ENSG00000069956	-0.04261251313702724	[3]	[0,2,1,0]	0	hSpCas9	positive selection	4212517
51960631	51960654	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.03946122426292087	[2]	[1,2,0,0]	0	hSpCas9	positive selection	4212518
52049987	52050010	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTATAGGGTCATCTTTCTGAAGG	MAPK6	ENSG00000069956	0.8744342618662504	[1]	[4,0,0,0]	6	hSpCas9	positive selection	4214646
51965915	51965938	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	-0.4388626063018884	[3]	[2,0]	-7	hSpCas9	positive selection	4279976
51960631	51960654	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	-0.7569605846937345	[3]	[1,0]	-9	hSpCas9	positive selection	4279977
51960649	51960672	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.5717161941229052	[3]	[1,0]	-8	hSpCas9	positive selection	4279978
51966271	51966294	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.396880806777282	[3]	[4,3]	7	hSpCas9	positive selection	4344232
51959977	51960000	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.23421943527114508	[3]	[2,1]	-5	hSpCas9	positive selection	4344233
51962388	51962411	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.02392000325453375	[2]	[2,1]	0	hSpCas9	positive selection	4344234
52046628	52046650	15	-	27760321	OCIAML3	viability	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-0.5363676680361589	[313,320]	[154,193]	-5	hSpCas9	negative selection	4416759
52046725	52046747	15	+	27760321	OCIAML3	viability	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.030342364152220136	[402,330]	[234,337]	0	hSpCas9	negative selection	4416760
52046974	52046996	15	+	27760321	OCIAML3	viability	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	0.59397029344476	[674,621]	[659,902]	7	hSpCas9	negative selection	4416761
52046628	52046650	15	-	27760321	OCIAML2	viability	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-0.7753207664311024	[313,320]	[132,173]	-7	hSpCas9	negative selection	4500222
52046725	52046747	15	+	27760321	OCIAML2	viability	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-1.0240901143310075	[402,330]	[102,200]	-7	hSpCas9	negative selection	4500223
52046974	52046996	15	+	27760321	OCIAML2	viability	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	0.4692972635824303	[674,621]	[711,744]	6	hSpCas9	negative selection	4500224
52046628	52046650	15	-	27760321	MV411	viability	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-0.8599329864510474	[313,320]	[23,253]	-5	hSpCas9	negative selection	4583685
52046725	52046747	15	+	27760321	MV411	viability	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-1.4024047366810146	[402,330]	[67,125]	-7	hSpCas9	negative selection	4583686
52046974	52046996	15	+	27760321	MV411	viability	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	0.6195388349119061	[674,621]	[467,941]	4	hSpCas9	negative selection	4583687
52046628	52046650	15	-	27760321	HL60	viability	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-0.40174181432057604	[313,320]	[234,156]	-4	hSpCas9	negative selection	4667148
52046725	52046747	15	+	27760321	HL60	viability	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.5814290369797952	[402,330]	[195,202]	-6	hSpCas9	negative selection	4667149
52046974	52046996	15	+	27760321	HL60	viability	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	0.23295958302912478	[674,621]	[689,550]	3	hSpCas9	negative selection	4667150
52046628	52046650	15	-	27760321	HT1080	viability	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-2.2815959488539588	[320,250]	[0,47]	-6	hSpCas9	negative selection	4750611
52046725	52046747	15	+	27760321	HT1080	viability	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.24895354512291762	[330,257]	[155,35]	-1	hSpCas9	negative selection	4750612
52046974	52046996	15	+	27760321	HT1080	viability	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	1.0047050937560993	[621,485]	[418,468]	5	hSpCas9	negative selection	4750613
52046628	52046650	15	-	27760321	HT29	viability after 7 days	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-0.23627924759580327	[320,250]	[271,332,324]	-3	hSpCas9	negative selection	4834074
52046725	52046747	15	+	27760321	HT29	viability after 7 days	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.13465113139667603	[330,257]	[369,649,225]	2	hSpCas9	negative selection	4834075
52046974	52046996	15	+	27760321	HT29	viability after 7 days	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	0.32312545732371734	[621,485]	[784,756,1107]	5	hSpCas9	negative selection	4834076
52046628	52046650	15	-	27760321	HT29	viability after 25 days	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-1.369389814133968	[320,250]	[177,89,105]	-7	hSpCas9	negative selection	4917537
52046725	52046747	15	+	27760321	HT29	viability after 25 days	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.2798820351245969	[330,257]	[255,268,310]	-3	hSpCas9	negative selection	4917538
52046974	52046996	15	+	27760321	HT29	viability after 25 days	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	0.25539849833400474	[621,485]	[746,787,728]	2	hSpCas9	negative selection	4917539
52046628	52046650	15	-	27760321	HT29	viability after 22 days	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-1.2121615765841827	[320,250]	[156,104,165]	-7	hSpCas9	negative selection	5001000
52046725	52046747	15	+	27760321	HT29	viability after 22 days	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.8086696861429499	[330,257]	[137,207,238]	-6	hSpCas9	negative selection	5001001
52046974	52046996	15	+	27760321	HT29	viability after 22 days	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	0.6227277253007251	[621,485]	[906,939,1114]	7	hSpCas9	negative selection	5001002
52046628	52046650	15	-	27760321	HT29	viability after 19 days	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-1.7994677713639136	[320,250]	[126,135,24]	-8	hSpCas9	negative selection	5084463
52046725	52046747	15	+	27760321	HT29	viability after 19 days	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.16359192736375472	[330,257]	[669,143,132]	-1	hSpCas9	negative selection	5084464
52046974	52046996	15	+	27760321	HT29	viability after 19 days	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	0.39501925070080857	[621,485]	[1006,1205,323]	4	hSpCas9	negative selection	5084465
52046628	52046650	15	-	27760321	HT29	viability after 16 days	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-0.6817858025435728	[320,250]	[297,151,158]	-6	hSpCas9	negative selection	5167926
52046725	52046747	15	+	27760321	HT29	viability after 16 days	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.31252516412941195	[330,257]	[322,237,240]	-3	hSpCas9	negative selection	5167927
52046974	52046996	15	+	27760321	HT29	viability after 16 days	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	0.18824555857377523	[621,485]	[842,574,716]	2	hSpCas9	negative selection	5167928
52046628	52046650	15	-	27760321	HT29	viability after 13 days	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-0.3509243444409837	[320,250]	[393,139,246]	-4	hSpCas9	negative selection	5251389
52046725	52046747	15	+	27760321	HT29	viability after 13 days	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.12087831147772865	[330,257]	[400,472,247]	1	hSpCas9	negative selection	5251390
52046974	52046996	15	+	27760321	HT29	viability after 13 days	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	0.44777528071083217	[621,485]	[939,954,742]	6	hSpCas9	negative selection	5251391
52046628	52046650	15	-	27760321	HT29	viability after 10 days	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-0.46822251357005223	[320,250]	[194,217,357]	-5	hSpCas9	negative selection	5334852
52046725	52046747	15	+	27760321	HT29	viability after 10 days	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.17532960870450365	[330,257]	[271,394,311]	-2	hSpCas9	negative selection	5334853
52046974	52046996	15	+	27760321	HT29	viability after 10 days	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	0.15229499838208527	[621,485]	[869,659,772]	2	hSpCas9	negative selection	5334854
52046628	52046650	15	-	27760321	MOLM13	viability	TAGAGCATGTTTGACACTCTGG	MAPK6	ENSG00000069956	-1.9435489542386748	[313,320]	[96,3]	-8	hSpCas9	negative selection	5418315
52046725	52046747	15	+	27760321	MOLM13	viability	AGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	1.2071304622249928	[402,330]	[693,289]	8	hSpCas9	negative selection	5418316
52046974	52046996	15	+	27760321	MOLM13	viability	TTTGGTCTTGCACGGATCATGG	MAPK6	ENSG00000069956	1.950663813355685	[674,621]	[2493,494]	9	hSpCas9	negative selection	5418317
51971720	51971743	15	-	27661255	K562	viability	GCGGATATGGAGGATCTCTTCGG	MAPK6	ENSG00000069956	-1.5110590522867082	[651,811]	[219,190]	-9	dCas9-KRAB	negative selection	5490089
51971733	51971756	15	-	27661255	K562	viability	GTGAGCGATAATGGCGGATATGG	MAPK6	ENSG00000069956	-1.127827355345282	[1348,1640]	[597,498]	-8	dCas9-KRAB	negative selection	5490090
51971739	51971762	15	-	27661255	K562	viability	GCGGACGTGAGCGATAATGGCGG	MAPK6	ENSG00000069956	-2.2857237354929	[501,459]	[79,77]	-9	dCas9-KRAB	negative selection	5490091
51971742	51971765	15	-	27661255	K562	viability	GCAGCGGACGTGAGCGATAATGG	MAPK6	ENSG00000069956	-2.2629363584296778	[542,506]	[107,69]	-9	dCas9-KRAB	negative selection	5490092
52019244	52019267	15	+	27661255	K562	viability	GGGTTACATGGCGGCGACTGCGG	MAPK6	ENSG00000069956	-0.09698064126027828	[1948,1928]	[1516,1389]	-4	dCas9-KRAB	negative selection	5492233
52019692	52019715	15	-	27661255	K562	viability	GCGCGGCCTGGCAGGGCGACCGG	MAPK6	ENSG00000069956	-0.32148474172702324	[365,474]	[266,267]	-7	dCas9-KRAB	negative selection	5492234
51965915	51965938	15	-	27260156	BXPC3	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.1388522228221178	[476]	[529,583,604,463]	3	hSpCas9	negative selection	5552436
51960631	51960654	15	+	27260156	BXPC3	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.014549246196087915	[478]	[429,546,440,620]	0	hSpCas9	negative selection	5552437
51960649	51960672	15	-	27260156	BXPC3	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.09908691440271687	[520]	[304,470,685,608]	-2	hSpCas9	negative selection	5552438
51966271	51966294	15	-	27260156	BXPC3	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	-0.017008154117431618	[892]	[775,842,1041,1063]	0	hSpCas9	negative selection	5616692
51959977	51960000	15	+	27260156	BXPC3	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.2300618282414577	[619]	[440,614,618,539]	-5	hSpCas9	negative selection	5616693
51962388	51962411	15	-	27260156	BXPC3	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.09436733479273096	[385]	[407,349,294,463]	-2	hSpCas9	negative selection	5616694
51965915	51965938	15	-	27260156	A673	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.11190965673673127	[476]	[601,525,639,711]	2	hSpCas9	negative selection	5673687
51960631	51960654	15	+	27260156	A673	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.0269875451058231	[478]	[646,604,483,615]	0	hSpCas9	negative selection	5673688
51960649	51960672	15	-	27260156	A673	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.11053214493268976	[520]	[673,526,521,607]	-3	hSpCas9	negative selection	5673689
51966271	51966294	15	-	27260156	A673	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.17375566498106654	[892]	[1441,1127,1211,1074]	4	hSpCas9	negative selection	5737943
51959977	51960000	15	+	27260156	A673	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.10578877045174029	[619]	[798,579,651,753]	-3	hSpCas9	negative selection	5737944
51962388	51962411	15	-	27260156	A673	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.2325519322002596	[385]	[434,394,417,329]	-5	hSpCas9	negative selection	5737945
51965915	51965938	15	-	27260156	A375	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	-0.17969181521661776	[476]	[485,445,514,509]	-3	hSpCas9	negative selection	5794938
51960631	51960654	15	+	27260156	A375	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.05092379317215545	[478]	[590,787,505,472]	0	hSpCas9	negative selection	5794939
51960649	51960672	15	-	27260156	A375	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.35079900445695855	[520]	[505,424,585,392]	-5	hSpCas9	negative selection	5794940
51966271	51966294	15	-	27260156	A375	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.04853418831516765	[892]	[963,1329,1288,795]	0	hSpCas9	negative selection	5859194
51959977	51960000	15	+	27260156	A375	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.303478448616172	[619]	[673,828,398,488]	-4	hSpCas9	negative selection	5859195
51962388	51962411	15	-	27260156	A375	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.14705789874995062	[385]	[229,556,437,419]	-2	hSpCas9	negative selection	5859196
51965915	51965938	15	-	27260156	COLO741	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.15783330512077737	[476]	[704,622,709]	3	hSpCas9	negative selection	5916189
51960631	51960654	15	+	27260156	COLO741	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.14197216355457612	[478]	[723,608,693]	3	hSpCas9	negative selection	5916190
51960649	51960672	15	-	27260156	COLO741	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.4183570482884106	[520]	[794,917,941]	8	hSpCas9	negative selection	5916191
51966271	51966294	15	-	27260156	COLO741	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.24734368672235685	[892]	[1748,1215,1143]	5	hSpCas9	negative selection	5980445
51959977	51960000	15	+	27260156	COLO741	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.13940685606047476	[619]	[823,792,559]	-3	hSpCas9	negative selection	5980446
51962388	51962411	15	-	27260156	COLO741	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.010693677370013865	[385]	[510,296,648]	0	hSpCas9	negative selection	5980447
51965915	51965938	15	-	27260156	CAL120	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.06762434215569833	[476]	[389,762,676]	1	hSpCas9	negative selection	6037440
51960631	51960654	15	+	27260156	CAL120	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	-0.19878797031538797	[478]	[481,428,638]	-3	hSpCas9	negative selection	6037441
51960649	51960672	15	-	27260156	CAL120	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.11417554294407026	[520]	[818,420,589]	-2	hSpCas9	negative selection	6037442
51966271	51966294	15	-	27260156	CAL120	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.022656894140531625	[892]	[1298,1172,942]	0	hSpCas9	negative selection	6101696
51959977	51960000	15	+	27260156	CAL120	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.06876799380917215	[619]	[1082,619,558]	-1	hSpCas9	negative selection	6101697
51962388	51962411	15	-	27260156	CAL120	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.29665194190171296	[385]	[432,448,298]	-4	hSpCas9	negative selection	6101698
51965915	51965938	15	-	27260156	CADOES1	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.10116919221134925	[476]	[517,481,487,412]	1	hSpCas9	negative selection	6158691
51960631	51960654	15	+	27260156	CADOES1	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.12475184343056676	[478]	[557,488,378,517]	2	hSpCas9	negative selection	6158692
51960649	51960672	15	-	27260156	CADOES1	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.174227088112055	[520]	[331,388,538,458]	-3	hSpCas9	negative selection	6158693
51966271	51966294	15	-	27260156	CADOES1	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.26050782255038696	[892]	[1153,744,770,1320]	4	hSpCas9	negative selection	6222947
51959977	51960000	15	+	27260156	CADOES1	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.5472990478203943	[619]	[466,406,289,414]	-7	hSpCas9	negative selection	6222948
51962388	51962411	15	-	27260156	CADOES1	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.2784017789217291	[385]	[339,291,201,351]	-5	hSpCas9	negative selection	6222949
51965915	51965938	15	-	27260156	EWS502	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	-0.12520565656343724	[476]	[516,358,453,522]	-2	hSpCas9	negative selection	6279942
51960631	51960654	15	+	27260156	EWS502	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	-0.32202332413404666	[478]	[594,307,312,383]	-5	hSpCas9	negative selection	6279943
51960649	51960672	15	-	27260156	EWS502	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.5510544551651101	[520]	[294,320,467,438]	-7	hSpCas9	negative selection	6279944
51966271	51966294	15	-	27260156	EWS502	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	-0.0019358667139113273	[892]	[1060,818,869,1019]	0	hSpCas9	negative selection	6344198
51959977	51960000	15	+	27260156	EWS502	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.6987246883795972	[619]	[478,261,508,361]	-8	hSpCas9	negative selection	6344199
51962388	51962411	15	-	27260156	EWS502	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.08089838161297513	[385]	[335,472,299,440]	-1	hSpCas9	negative selection	6344200
51965915	51965938	15	-	27260156	EW8	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.2991321283932143	[476]	[526,403,555,405]	5	hSpCas9	negative selection	6401193
51960631	51960654	15	+	27260156	EW8	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.2858628198059349	[478]	[598,423,343,559]	5	hSpCas9	negative selection	6401194
51960649	51960672	15	-	27260156	EW8	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.1129175707471988	[520]	[585,398,397,465]	2	hSpCas9	negative selection	6401195
51966271	51966294	15	-	27260156	EW8	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.25555850640964684	[892]	[1065,981,587,886]	5	hSpCas9	negative selection	6465449
51959977	51960000	15	+	27260156	EW8	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.053741531111170415	[619]	[555,605,411,381]	-1	hSpCas9	negative selection	6465450
51962388	51962411	15	-	27260156	EW8	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.11413588143151673	[385]	[343,379,273,366]	2	hSpCas9	negative selection	6465451
51965915	51965938	15	-	27260156	CORL105	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	-0.034404962119900635	[476]	[454,562,800,398]	0	hSpCas9	negative selection	6522444
51960631	51960654	15	+	27260156	CORL105	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.26466798311121376	[478]	[632,624,825,633]	5	hSpCas9	negative selection	6522445
51960649	51960672	15	-	27260156	CORL105	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.7579580941152378	[520]	[452,284,383,328]	-8	hSpCas9	negative selection	6522446
51966271	51966294	15	-	27260156	CORL105	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	-0.0050248654126439085	[892]	[1039,837,1173,1138]	0	hSpCas9	negative selection	6586700
51959977	51960000	15	+	27260156	CORL105	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.5442869009205885	[619]	[449,519,581,449]	-7	hSpCas9	negative selection	6586701
51962388	51962411	15	-	27260156	CORL105	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.4250109923748223	[385]	[449,267,388,252]	-7	hSpCas9	negative selection	6586702
51965915	51965938	15	-	27260156	HS294T	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.36893971224445876	[476]	[97,258,283,340]	5	hSpCas9	negative selection	6643695
51960631	51960654	15	+	27260156	HS294T	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.11507479986617801	[478]	[191,187,171,260]	1	hSpCas9	negative selection	6643696
51960649	51960672	15	-	27260156	HS294T	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.36252535715770207	[520]	[203,373,196,261]	5	hSpCas9	negative selection	6643697
51966271	51966294	15	-	27260156	HS294T	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.017682385607253215	[892]	[352,287,391,368]	0	hSpCas9	negative selection	6707951
51959977	51960000	15	+	27260156	HS294T	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.5290229744769169	[619]	[155,149,165,198]	-6	hSpCas9	negative selection	6707952
51962388	51962411	15	-	27260156	HS294T	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.1613912071122371	[385]	[124,179,96,129]	-2	hSpCas9	negative selection	6707953
51965915	51965938	15	-	27260156	HCC44	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.25923754058684184	[476]	[738,338,814,761]	4	hSpCas9	negative selection	6764946
51960631	51960654	15	+	27260156	HCC44	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	-0.1027178862246584	[478]	[524,385,694,460]	-2	hSpCas9	negative selection	6764947
51960649	51960672	15	-	27260156	HCC44	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.10492520632428651	[520]	[527,506,862,353]	-2	hSpCas9	negative selection	6764948
51966271	51966294	15	-	27260156	HCC44	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.2011010904445214	[892]	[1256,943,1489,1043]	3	hSpCas9	negative selection	6829202
51959977	51960000	15	+	27260156	HCC44	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.34112169018484795	[619]	[759,495,428,530]	-5	hSpCas9	negative selection	6829203
51962388	51962411	15	-	27260156	HCC44	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.031004570053126068	[385]	[436,355,495,509]	0	hSpCas9	negative selection	6829204
51965915	51965938	15	-	27260156	G402	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	-0.09614803124712665	[476]	[704,512,534,448]	-1	hSpCas9	negative selection	6886197
51960631	51960654	15	+	27260156	G402	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.0736496952056884	[478]	[908,423,661,499]	0	hSpCas9	negative selection	6886198
51960649	51960672	15	-	27260156	G402	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.4078748201751965	[520]	[369,323,779,418]	-5	hSpCas9	negative selection	6886199
51966271	51966294	15	-	27260156	G402	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.0892784785520695	[892]	[1496,1318,982,903]	1	hSpCas9	negative selection	6950453
51959977	51960000	15	+	27260156	G402	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.48396172958813766	[619]	[862,397,380,556]	-6	hSpCas9	negative selection	6950454
51962388	51962411	15	-	27260156	G402	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.41271375637287255	[385]	[732,672,797,333]	5	hSpCas9	negative selection	6950455
51965915	51965938	15	-	27260156	L33	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.2699271151586395	[476]	[496,269,355,579]	6	hSpCas9	negative selection	7007448
51960631	51960654	15	+	27260156	L33	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.3660167321330499	[478]	[660,240,348,662]	7	hSpCas9	negative selection	7007449
51960649	51960672	15	-	27260156	L33	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.014587058779167689	[520]	[518,207,370,446]	0	hSpCas9	negative selection	7007450
51966271	51966294	15	-	27260156	L33	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.1267055044641492	[892]	[912,479,522,983]	3	hSpCas9	negative selection	7071704
51959977	51960000	15	+	27260156	L33	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.1831758123458224	[619]	[492,214,406,520]	-4	hSpCas9	negative selection	7071705
51962388	51962411	15	-	27260156	L33	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.05120606419026094	[385]	[465,186,163,413]	1	hSpCas9	negative selection	7071706
51965915	51965938	15	-	27260156	K562	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.17823873300307153	[476]	[597,335,577,411]	2	hSpCas9	negative selection	7128699
51960631	51960654	15	+	27260156	K562	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.2491223888906212	[478]	[320,474,436,740]	3	hSpCas9	negative selection	7128700
51960649	51960672	15	-	27260156	K562	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.27735605833075594	[520]	[465,421,401,257]	-3	hSpCas9	negative selection	7128701
51966271	51966294	15	-	27260156	K562	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	-0.11409423146351338	[892]	[589,716,578,995]	-1	hSpCas9	negative selection	7192955
51959977	51960000	15	+	27260156	K562	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.6440948030752994	[619]	[448,354,259,350]	-6	hSpCas9	negative selection	7192956
51962388	51962411	15	-	27260156	K562	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.06725749663578437	[385]	[176,587,314,351]	0	hSpCas9	negative selection	7192957
51965915	51965938	15	-	27260156	HT29	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.3991100050154577	[476]	[869,839,632,728]	7	hSpCas9	negative selection	7249950
51960631	51960654	15	+	27260156	HT29	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.2451856570078362	[478]	[693,674,887,518]	5	hSpCas9	negative selection	7249951
51960649	51960672	15	-	27260156	HT29	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.41261426694714765	[520]	[907,907,685,870]	7	hSpCas9	negative selection	7249952
51966271	51966294	15	-	27260156	HT29	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.1555200114949249	[892]	[1374,1333,1147,1017]	3	hSpCas9	negative selection	7314206
51959977	51960000	15	+	27260156	HT29	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	0.027495055990593542	[619]	[655,1079,847,530]	0	hSpCas9	negative selection	7314207
51962388	51962411	15	-	27260156	HT29	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.03256811076033733	[385]	[475,468,489,479]	0	hSpCas9	negative selection	7314208
51965915	51965938	15	-	27260156	MHHES1	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	-0.07646674713927692	[476]	[346,674,561,452]	-1	hSpCas9	negative selection	7371201
51960631	51960654	15	+	27260156	MHHES1	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	-0.08241260511596186	[478]	[579,597,629,288]	-1	hSpCas9	negative selection	7371202
51960649	51960672	15	-	27260156	MHHES1	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.005007592336494254	[520]	[913,643,464,392]	0	hSpCas9	negative selection	7371203
51966271	51966294	15	-	27260156	MHHES1	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.015351893182914966	[892]	[798,1357,1155,791]	0	hSpCas9	negative selection	7435457
51959977	51960000	15	+	27260156	MHHES1	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.49489427478886594	[619]	[621,483,539,368]	-7	hSpCas9	negative selection	7435458
51962388	51962411	15	-	27260156	MHHES1	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.2408750534395805	[385]	[427,385,377,296]	-4	hSpCas9	negative selection	7435459
51965915	51965938	15	-	27260156	MEWO	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.3499046366661761	[476]	[684,496,546]	7	hSpCas9	negative selection	7492452
51960631	51960654	15	+	27260156	MEWO	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	-0.1586125417313159	[478]	[568,359,307]	-3	hSpCas9	negative selection	7492453
51960649	51960672	15	-	27260156	MEWO	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.18910530595857625	[520]	[731,374,594]	4	hSpCas9	negative selection	7492454
51966271	51966294	15	-	27260156	MEWO	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.33292736217626895	[892]	[1067,999,1091]	7	hSpCas9	negative selection	7556708
51959977	51960000	15	+	27260156	MEWO	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.020686622159288792	[619]	[575,583,555]	0	hSpCas9	negative selection	7556709
51962388	51962411	15	-	27260156	MEWO	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.6141151532928052	[385]	[150,296,242]	-8	hSpCas9	negative selection	7556710
51965915	51965938	15	-	27260156	LNCAPCLONEFGC	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.01586502362395511	[476]	[367,486,576,333]	0	hSpCas9	negative selection	7613703
51960631	51960654	15	+	27260156	LNCAPCLONEFGC	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.08860612424910545	[478]	[376,602,403,444]	1	hSpCas9	negative selection	7613704
51960649	51960672	15	-	27260156	LNCAPCLONEFGC	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.049905266935936804	[520]	[495,451,520,491]	0	hSpCas9	negative selection	7613705
51966271	51966294	15	-	27260156	LNCAPCLONEFGC	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.1257043576966197	[892]	[810,789,988,962]	2	hSpCas9	negative selection	7677959
51959977	51960000	15	+	27260156	LNCAPCLONEFGC	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.05785598755916749	[619]	[703,406,556,497]	-1	hSpCas9	negative selection	7677960
51962388	51962411	15	-	27260156	LNCAPCLONEFGC	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.046681728499574915	[385]	[369,322,376,289]	0	hSpCas9	negative selection	7677961
51965915	51965938	15	-	27260156	PANC0327	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.7398619338912252	[476]	[435,579,612,1194]	9	hSpCas9	negative selection	7734954
51960631	51960654	15	+	27260156	PANC0327	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.0840434909716412	[478]	[239,726,406,376]	1	hSpCas9	negative selection	7734955
51960649	51960672	15	-	27260156	PANC0327	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.07782056131286823	[520]	[512,514,342,378]	-1	hSpCas9	negative selection	7734956
51966271	51966294	15	-	27260156	PANC0327	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.16044654566328354	[892]	[1335,551,848,888]	2	hSpCas9	negative selection	7799210
51959977	51960000	15	+	27260156	PANC0327	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.36633632238115577	[619]	[314,256,668,480]	-5	hSpCas9	negative selection	7799211
51962388	51962411	15	-	27260156	PANC0327	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.3033824052880829	[385]	[318,243,237,317]	-4	hSpCas9	negative selection	7799212
51965915	51965938	15	-	27260156	NCIH2009	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.3051946314084333	[476]	[1086,439,1000]	4	hSpCas9	negative selection	7856205
51960631	51960654	15	+	27260156	NCIH2009	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.12404662153222416	[478]	[933,574,720]	1	hSpCas9	negative selection	7856206
51960649	51960672	15	-	27260156	NCIH2009	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.17249769310918805	[520]	[698,538,710]	-2	hSpCas9	negative selection	7856207
51966271	51966294	15	-	27260156	NCIH2009	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.15981796634524814	[892]	[1373,1127,1677]	2	hSpCas9	negative selection	7920461
51959977	51960000	15	+	27260156	NCIH2009	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.36819188658723384	[619]	[753,538,737]	-5	hSpCas9	negative selection	7920462
51962388	51962411	15	-	27260156	NCIH2009	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.4138682474101051	[385]	[495,280,456]	-5	hSpCas9	negative selection	7920463
51965915	51965938	15	-	27260156	NCIH1373	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	-0.21558370292618073	[476]	[547,263,619,114]	-2	hSpCas9	negative selection	7977456
51960631	51960654	15	+	27260156	NCIH1373	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	-0.279773322254623	[478]	[465,427,502,96]	-3	hSpCas9	negative selection	7977457
51960649	51960672	15	-	27260156	NCIH1373	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.013465376715830701	[520]	[795,562,520,132]	0	hSpCas9	negative selection	7977458
51966271	51966294	15	-	27260156	NCIH1373	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.08470164713813877	[892]	[1231,876,1352,210]	0	hSpCas9	negative selection	8041712
51959977	51960000	15	+	27260156	NCIH1373	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	0.13969388089789692	[619]	[904,423,317,400]	1	hSpCas9	negative selection	8041713
51962388	51962411	15	-	27260156	NCIH1373	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.17239016295924808	[385]	[603,407,253,77]	-2	hSpCas9	negative selection	8041714
51965915	51965938	15	-	27260156	PATU8902	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.2584510031745822	[476]	[1197,748,433,890]	2	hSpCas9	negative selection	8098707
51960631	51960654	15	+	27260156	PATU8902	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.1702973392666494	[478]	[467,1058,705,783]	1	hSpCas9	negative selection	8098708
51960649	51960672	15	-	27260156	PATU8902	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.05825168897445454	[520]	[482,562,789,954]	0	hSpCas9	negative selection	8098709
51966271	51966294	15	-	27260156	PATU8902	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.046406419286250444	[892]	[1358,965,1071,1850]	0	hSpCas9	negative selection	8162963
51959977	51960000	15	+	27260156	PATU8902	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-1.437644339221986	[619]	[429,274,230,362]	-8	hSpCas9	negative selection	8162964
51962388	51962411	15	-	27260156	PATU8902	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.32101231241277217	[385]	[344,475,256,720]	-3	hSpCas9	negative selection	8162965
51965915	51965938	15	-	27260156	PANC1	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.12132293498138767	[476]	[604,377,521,280]	2	hSpCas9	negative selection	8219958
51960631	51960654	15	+	27260156	PANC1	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.3922718831666834	[478]	[575,671,474,465]	6	hSpCas9	negative selection	8219959
51960649	51960672	15	-	27260156	PANC1	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.08810048040784801	[520]	[369,502,455,373]	-1	hSpCas9	negative selection	8219960
51966271	51966294	15	-	27260156	PANC1	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.03787775956447781	[892]	[760,955,688,767]	0	hSpCas9	negative selection	8284214
51959977	51960000	15	+	27260156	PANC1	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	0.07361146250813977	[619]	[568,470,639,537]	1	hSpCas9	negative selection	8284215
51962388	51962411	15	-	27260156	PANC1	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.08167641879689519	[385]	[359,393,348,309]	1	hSpCas9	negative selection	8284216
51965915	51965938	15	-	27260156	PANC0813	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	-0.035338369257708696	[476]	[644,611,555,390]	0	hSpCas9	negative selection	8341209
51960631	51960654	15	+	27260156	PANC0813	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	-0.23593462067028387	[478]	[527,494,454,438]	-4	hSpCas9	negative selection	8341210
51960649	51960672	15	-	27260156	PANC0813	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.7936417623751484	[520]	[437,286,350,343]	-8	hSpCas9	negative selection	8341211
51966271	51966294	15	-	27260156	PANC0813	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.17985275389545885	[892]	[1235,1161,1301,1062]	3	hSpCas9	negative selection	8405465
51959977	51960000	15	+	27260156	PANC0813	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.8676392568965354	[619]	[344,396,396,448]	-8	hSpCas9	negative selection	8405466
51962388	51962411	15	-	27260156	PANC0813	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.39641158260979314	[385]	[490,351,370,185]	-6	hSpCas9	negative selection	8405467
51965915	51965938	15	-	27260156	RDES	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.22039048700542108	[476]	[530,603,738,702]	3	hSpCas9	negative selection	8462460
51960631	51960654	15	+	27260156	RDES	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.11758091930763241	[478]	[556,473,605,783]	2	hSpCas9	negative selection	8462461
51960649	51960672	15	-	27260156	RDES	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.08713765646025426	[520]	[525,605,569,886]	1	hSpCas9	negative selection	8462462
51966271	51966294	15	-	27260156	RDES	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.318417228085909	[892]	[1034,1346,1440,1317]	5	hSpCas9	negative selection	8526716
51959977	51960000	15	+	27260156	RDES	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.21927633799653212	[619]	[678,438,563,770]	-4	hSpCas9	negative selection	8526717
51962388	51962411	15	-	27260156	RDES	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.14587618376375325	[385]	[300,488,541,693]	2	hSpCas9	negative selection	8526718
51965915	51965938	15	-	27260156	PC3	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.29895777131014906	[476]	[351,618,642,801]	6	hSpCas9	negative selection	8583711
51960631	51960654	15	+	27260156	PC3	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.09220615889705032	[478]	[380,366,833,590]	2	hSpCas9	negative selection	8583712
51960649	51960672	15	-	27260156	PC3	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.12764433366616082	[520]	[369,550,543,445]	-3	hSpCas9	negative selection	8583713
51966271	51966294	15	-	27260156	PC3	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.2962102642150308	[892]	[666,1342,1808,888]	6	hSpCas9	negative selection	8647967
51959977	51960000	15	+	27260156	PC3	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.320415390216066	[619]	[329,376,741,662]	-6	hSpCas9	negative selection	8647968
51962388	51962411	15	-	27260156	PC3	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.20251089695293378	[385]	[239,292,425,424]	-4	hSpCas9	negative selection	8647969
51965915	51965938	15	-	27260156	PATU8988T	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.4035500472275823	[476]	[487,792,520,658]	7	hSpCas9	negative selection	8704962
51960631	51960654	15	+	27260156	PATU8988T	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.3738788940467625	[478]	[505,593,639,662]	6	hSpCas9	negative selection	8704963
51960649	51960672	15	-	27260156	PATU8988T	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.12667911432367843	[520]	[481,432,653,622]	2	hSpCas9	negative selection	8704964
51966271	51966294	15	-	27260156	PATU8988T	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.4151184086324631	[892]	[1102,1393,1041,1081]	7	hSpCas9	negative selection	8769218
51959977	51960000	15	+	27260156	PATU8988T	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.10298262179761897	[619]	[566,517,565,577]	-2	hSpCas9	negative selection	8769219
51962388	51962411	15	-	27260156	PATU8988T	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.46847341061206427	[385]	[292,524,572,686]	7	hSpCas9	negative selection	8769220
51965915	51965938	15	-	27260156	T47D	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.23417742573132116	[476]	[683,635,685,607]	5	hSpCas9	negative selection	8826213
51960631	51960654	15	+	27260156	T47D	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.06596435826246058	[478]	[559,527,602,651]	1	hSpCas9	negative selection	8826214
51960649	51960672	15	-	27260156	T47D	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.10861893029270178	[520]	[738,571,677,634]	2	hSpCas9	negative selection	8826215
51966271	51966294	15	-	27260156	T47D	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.18572055361879225	[892]	[1204,991,1274,1278]	4	hSpCas9	negative selection	8890469
51959977	51960000	15	+	27260156	T47D	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.10931576752640204	[619]	[594,536,842,712]	-2	hSpCas9	negative selection	8890470
51962388	51962411	15	-	27260156	T47D	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.16071028769655177	[385]	[532,445,494,542]	3	hSpCas9	negative selection	8890471
51965915	51965938	15	-	27260156	SU8686	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.6382958389987661	[476]	[594,671,790,939]	9	hSpCas9	negative selection	8947464
51960631	51960654	15	+	27260156	SU8686	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.5571653698959633	[478]	[590,766,682,761]	8	hSpCas9	negative selection	8947465
51960649	51960672	15	-	27260156	SU8686	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	0.38534631766750793	[520]	[712,655,565,768]	6	hSpCas9	negative selection	8947466
51966271	51966294	15	-	27260156	SU8686	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.2824958834799036	[892]	[1124,943,1065,1194]	5	hSpCas9	negative selection	9011720
51959977	51960000	15	+	27260156	SU8686	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	0.21591377843959736	[619]	[616,693,634,954]	3	hSpCas9	negative selection	9011721
51962388	51962411	15	-	27260156	SU8686	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.28569221339988277	[385]	[376,513,402,590]	5	hSpCas9	negative selection	9011722
51965915	51965938	15	-	27260156	SKES1	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.013484403448078865	[476]	[576,525,543,307]	0	hSpCas9	negative selection	9068715
51960631	51960654	15	+	27260156	SKES1	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.16520304486544238	[478]	[649,392,610,486]	3	hSpCas9	negative selection	9068716
51960649	51960672	15	-	27260156	SKES1	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.03724248518338312	[520]	[515,639,505,389]	-1	hSpCas9	negative selection	9068717
51966271	51966294	15	-	27260156	SKES1	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.03681166675769221	[892]	[884,1078,835,867]	0	hSpCas9	negative selection	9132971
51959977	51960000	15	+	27260156	SKES1	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.12926598858161498	[619]	[542,702,659,383]	-3	hSpCas9	negative selection	9132972
51962388	51962411	15	-	27260156	SKES1	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.10784365716266187	[385]	[447,485,302,430]	2	hSpCas9	negative selection	9132973
51965915	51965938	15	-	27260156	TOV112D	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.0278985785003003	[476]	[435,662,564,326]	0	hSpCas9	negative selection	9189966
51960631	51960654	15	+	27260156	TOV112D	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	-0.3579517051938036	[478]	[323,438,429,316]	-6	hSpCas9	negative selection	9189967
51960649	51960672	15	-	27260156	TOV112D	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.3625622633338107	[520]	[377,584,386,316]	-6	hSpCas9	negative selection	9189968
51966271	51966294	15	-	27260156	TOV112D	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.17038407456665428	[892]	[1231,998,1003,811]	3	hSpCas9	negative selection	9254222
51959977	51960000	15	+	27260156	TOV112D	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.049601073039591326	[619]	[379,643,831,536]	-1	hSpCas9	negative selection	9254223
51962388	51962411	15	-	27260156	TOV112D	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	0.14226026361539135	[385]	[620,335,388,355]	2	hSpCas9	negative selection	9254224
51965915	51965938	15	-	27260156	TC71	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	0.22808080028687522	[476]	[615,530,632,614]	5	hSpCas9	negative selection	9311217
51960631	51960654	15	+	27260156	TC71	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.11148623632306341	[478]	[653,450,531,581]	3	hSpCas9	negative selection	9311218
51960649	51960672	15	-	27260156	TC71	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.03087785757939497	[520]	[610,439,504,635]	0	hSpCas9	negative selection	9311219
51966271	51966294	15	-	27260156	TC71	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.0007736228262713585	[892]	[824,981,939,1095]	0	hSpCas9	negative selection	9375473
51959977	51960000	15	+	27260156	TC71	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.26337284767740005	[619]	[670,480,424,644]	-6	hSpCas9	negative selection	9375474
51962388	51962411	15	-	27260156	TC71	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.39553384570880235	[385]	[272,340,325,318]	-8	hSpCas9	negative selection	9375475
51965915	51965938	15	-	27260156	TC32	viability	AGGCTAATTCTGATGATGAACGG	MAPK6	ENSG00000069956	-0.12477396485088883	[476]	[431,287,619,356]	-2	hSpCas9	negative selection	9432468
51960631	51960654	15	+	27260156	TC32	viability	TGACTTACAACAGGCTGTCCTGG	MAPK6	ENSG00000069956	0.030149173451569155	[478]	[466,259,581,607]	0	hSpCas9	negative selection	9432469
51960649	51960672	15	-	27260156	TC32	viability	GAAGACAAACCACCTACTCCAGG	MAPK6	ENSG00000069956	-0.1470991884540599	[520]	[421,402,510,432]	-3	hSpCas9	negative selection	9432470
51966271	51966294	15	-	27260156	TC32	viability	TTCTGAGCGTTCTGACCATGAGG	MAPK6	ENSG00000069956	0.1586993678754951	[892]	[977,613,1078,1175]	3	hSpCas9	negative selection	9496724
51959977	51960000	15	+	27260156	TC32	viability	TCTACTTCTATTCTGGTCTCAGG	MAPK6	ENSG00000069956	-0.48838318378061807	[619]	[263,292,654,540]	-7	hSpCas9	negative selection	9496725
51962388	51962411	15	-	27260156	TC32	viability	AGTGACACTGAGGTGCCAAAAGG	MAPK6	ENSG00000069956	-0.3607053830560989	[385]	[185,283,343,322]	-6	hSpCas9	negative selection	9496726
52046724	52046747	15	+	28162770	P31FUJ	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.44526970069825916	[264]	[423]	5	hSpCas9	negative selection	10189107
52046533	52046556	15	-	28162770	P31FUJ	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.33222144925344665	[339]	[502]	3	hSpCas9	negative selection	10189108
52046524	52046547	15	+	28162770	P31FUJ	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.5159726920414609	[218]	[367]	6	hSpCas9	negative selection	10189109
52046701	52046724	15	+	28162770	P31FUJ	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	-0.0007596130442114601	[148]	[174]	0	hSpCas9	negative selection	10189110
52046956	52046979	15	+	28162770	P31FUJ	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	0.5062377179896861	[277]	[463]	6	hSpCas9	negative selection	10189111
52046724	52046747	15	+	28162770	TF1	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	NaN	[NaN]	[176]	1	hSpCas9	negative selection	10358473
52046533	52046556	15	-	28162770	TF1	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	NaN	[NaN]	[226]	1	hSpCas9	negative selection	10358474
52046524	52046547	15	+	28162770	TF1	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	NaN	[NaN]	[131]	1	hSpCas9	negative selection	10358475
52046701	52046724	15	+	28162770	TF1	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	NaN	[NaN]	[216]	1	hSpCas9	negative selection	10358476
52046956	52046979	15	+	28162770	TF1	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	NaN	[NaN]	[352]	1	hSpCas9	negative selection	10358477
52046724	52046747	15	+	28162770	SKM1	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.02212739109323114	[82]	[148]	0	hSpCas9	negative selection	10527839
52046533	52046556	15	-	28162770	SKM1	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	-0.6469149914639144	[92]	[104]	-5	hSpCas9	negative selection	10527840
52046524	52046547	15	+	28162770	SKM1	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	-0.28143331665930277	[65]	[95]	-2	hSpCas9	negative selection	10527841
52046701	52046724	15	+	28162770	SKM1	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	-0.5071283606685936	[40]	[50]	-4	hSpCas9	negative selection	10527842
52046956	52046979	15	+	28162770	SKM1	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	-0.40189320919573973	[70]	[94]	-3	hSpCas9	negative selection	10527843
52046724	52046747	15	+	28162770	SKM1	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.02212739109323114	[82]	[148]	0	hSpCas9	negative selection	10697205
52046533	52046556	15	-	28162770	SKM1	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	-0.6469149914639144	[92]	[104]	-5	hSpCas9	negative selection	10697206
52046524	52046547	15	+	28162770	SKM1	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	-0.28143331665930277	[65]	[95]	-2	hSpCas9	negative selection	10697207
52046701	52046724	15	+	28162770	SKM1	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	-0.5071283606685936	[40]	[50]	-4	hSpCas9	negative selection	10697208
52046956	52046979	15	+	28162770	SKM1	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	-0.40189320919573973	[70]	[94]	-3	hSpCas9	negative selection	10697209
52046724	52046747	15	+	28162770	PL21	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	1.6362387292959935	[254]	[344]	9	hSpCas9	negative selection	10866571
52046533	52046556	15	-	28162770	PL21	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.3340940711581841	[369]	[202]	3	hSpCas9	negative selection	10866572
52046524	52046547	15	+	28162770	PL21	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	-0.7123975442603406	[191]	[50]	-5	hSpCas9	negative selection	10866573
52046701	52046724	15	+	28162770	PL21	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	0.7774485426670411	[125]	[93]	6	hSpCas9	negative selection	10866574
52046956	52046979	15	+	28162770	PL21	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	0.3135214139070625	[158]	[85]	2	hSpCas9	negative selection	10866575
52046724	52046747	15	+	28162770	P31FUJ	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.44526970069825916	[264]	[423]	5	hSpCas9	negative selection	11035937
52046533	52046556	15	-	28162770	P31FUJ	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.33222144925344665	[339]	[502]	3	hSpCas9	negative selection	11035938
52046524	52046547	15	+	28162770	P31FUJ	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.5159726920414609	[218]	[367]	6	hSpCas9	negative selection	11035939
52046701	52046724	15	+	28162770	P31FUJ	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	-0.0007596130442114601	[148]	[174]	0	hSpCas9	negative selection	11035940
52046956	52046979	15	+	28162770	P31FUJ	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	0.5062377179896861	[277]	[463]	6	hSpCas9	negative selection	11035941
52046724	52046747	15	+	28162770	OCIAML5	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.3148572015912089	[214]	[311]	-2	hSpCas9	negative selection	11205303
52046533	52046556	15	-	28162770	OCIAML5	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	-0.360886216463458	[142]	[200]	-3	hSpCas9	negative selection	11205304
52046524	52046547	15	+	28162770	OCIAML5	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	-0.5041432674436901	[164]	[209]	-3	hSpCas9	negative selection	11205305
52046701	52046724	15	+	28162770	OCIAML5	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	0.9193090540880404	[57]	[197]	7	hSpCas9	negative selection	11205306
52046956	52046979	15	+	28162770	OCIAML5	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	-0.08401329891369386	[100]	[171]	0	hSpCas9	negative selection	11205307
52046724	52046747	15	+	28162770	EOL1	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.4181951055457448	[499]	[351]	4	hSpCas9	negative selection	11374669
52046533	52046556	15	-	28162770	EOL1	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.14284386263904425	[654]	[380]	1	hSpCas9	negative selection	11374670
52046524	52046547	15	+	28162770	EOL1	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.5180074489682309	[394]	[297]	5	hSpCas9	negative selection	11374671
52046701	52046724	15	+	28162770	EOL1	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	-1.5239127292457595	[261]	[47]	-7	hSpCas9	negative selection	11374672
52046956	52046979	15	+	28162770	EOL1	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	-0.7916592624288743	[321]	[97]	-5	hSpCas9	negative selection	11374673
52046724	52046747	15	+	28162770	MOLM13	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.16047990669177692	[387]	[250]	-1	hSpCas9	negative selection	11544035
52046533	52046556	15	-	28162770	MOLM13	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.528673890057388	[487]	[508]	4	hSpCas9	negative selection	11544036
52046524	52046547	15	+	28162770	MOLM13	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.07391349779356474	[271]	[206]	0	hSpCas9	negative selection	11544037
52046701	52046724	15	+	28162770	MOLM13	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	-0.9716426796550137	[197]	[72]	-5	hSpCas9	negative selection	11544038
52046956	52046979	15	+	28162770	MOLM13	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	0.23677015578754715	[303]	[258]	1	hSpCas9	negative selection	11544039
52046724	52046747	15	+	28162770	HEL	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.23594869310428934	[406]	[306]	2	hSpCas9	negative selection	11713401
52046533	52046556	15	-	28162770	HEL	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.6720166245226027	[438]	[447]	6	hSpCas9	negative selection	11713402
52046524	52046547	15	+	28162770	HEL	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.24378831688914965	[326]	[247]	2	hSpCas9	negative selection	11713403
52046701	52046724	15	+	28162770	HEL	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	0.36145272161034053	[174]	[143]	3	hSpCas9	negative selection	11713404
52046956	52046979	15	+	28162770	HEL	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	0.34496163656406453	[310]	[252]	3	hSpCas9	negative selection	11713405
52046724	52046747	15	+	28162770	MV411	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.9234351276575545	[260]	[416]	8	hSpCas9	negative selection	11882767
52046533	52046556	15	-	28162770	MV411	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	-0.023477378185264575	[256]	[212]	0	hSpCas9	negative selection	11882768
52046524	52046547	15	+	28162770	MV411	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.45136843627168616	[190]	[219]	4	hSpCas9	negative selection	11882769
52046701	52046724	15	+	28162770	MV411	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	-0.8338625513190727	[145]	[68]	-5	hSpCas9	negative selection	11882770
52046956	52046979	15	+	28162770	MV411	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	0.41016705082088367	[200]	[224]	3	hSpCas9	negative selection	11882771
52046724	52046747	15	+	28162770	MONOMAC1	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.421077121277484	[145]	[124]	-4	hSpCas9	negative selection	12052133
52046533	52046556	15	-	28162770	MONOMAC1	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.3147725413217253	[208]	[297]	3	hSpCas9	negative selection	12052134
52046524	52046547	15	+	28162770	MONOMAC1	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.03391758778031845	[143]	[168]	0	hSpCas9	negative selection	12052135
52046701	52046724	15	+	28162770	MONOMAC1	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	-1.356693513048039	[104]	[46]	-7	hSpCas9	negative selection	12052136
52046956	52046979	15	+	28162770	MONOMAC1	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	-0.3657913047939283	[153]	[136]	-3	hSpCas9	negative selection	12052137
52046724	52046747	15	+	28162770	OCIAML2	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	-0.05432290657575145	[70]	[378]	0	hSpCas9	negative selection	12221499
52046533	52046556	15	-	28162770	OCIAML2	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	-0.17178534346784013	[62]	[309]	-1	hSpCas9	negative selection	12221500
52046524	52046547	15	+	28162770	OCIAML2	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.6402159434461291	[35]	[310]	6	hSpCas9	negative selection	12221501
52046701	52046724	15	+	28162770	OCIAML2	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	0.27130202181739427	[28]	[193]	2	hSpCas9	negative selection	12221502
52046956	52046979	15	+	28162770	OCIAML2	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	-0.24181113474628027	[31]	[149]	-2	hSpCas9	negative selection	12221503
52046724	52046747	15	+	28162770	OCIAML3	viability	AAGCCAATTAACAGACGATGTGG	MAPK6	ENSG00000069956	0.29838338558924016	[79]	[296]	3	hSpCas9	negative selection	12390865
52046533	52046556	15	-	28162770	OCIAML3	viability	CCATTGCCTCCACAACCCAATGG	MAPK6	ENSG00000069956	0.8770352686834226	[89]	[498]	7	hSpCas9	negative selection	12390866
52046524	52046547	15	+	28162770	OCIAML3	viability	GACTTAAAACCATTGGGTTGTGG	MAPK6	ENSG00000069956	0.664395316777985	[64]	[310]	6	hSpCas9	negative selection	12390867
52046701	52046724	15	+	28162770	OCIAML3	viability	TTTGAGATTCTTGGTCCCAGTGG	MAPK6	ENSG00000069956	1.1644376812524946	[29]	[202]	8	hSpCas9	negative selection	12390868
52046956	52046979	15	+	28162770	OCIAML3	viability	GTGCTGAAGATAGGTGACTTTGG	MAPK6	ENSG00000069956	1.5471930720815184	[61]	[546]	9	hSpCas9	negative selection	12390869