Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5599
• Symbol:MAPK8
• Description:mitogen-activated protein kinase 8

DataSource: http://genomecrispr.dkfz.de/#!/results/MAPK8

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
48427117	48427140	10	+	26472758	Jiyoye	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-1.2125525373759596	[125]	[40]	-7	hSpCas9	negative selection	96329
48425948	48425971	10	+	26472758	Jiyoye	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	1.3400611856473363	[32]	[62]	7	hSpCas9	negative selection	96330
48431259	48431282	10	-	26472758	Jiyoye	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	0.22331118910568745	[116]	[102]	1	hSpCas9	negative selection	96331
48420199	48420222	10	+	26472758	Jiyoye	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	0.9921378822270296	[37]	[56]	6	hSpCas9	negative selection	96332
48420268	48420291	10	+	26472758	Jiyoye	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	1.1149946300125633	[59]	[97]	7	hSpCas9	negative selection	96333
48420295	48420318	10	-	26472758	Jiyoye	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	-0.6976208085057365	[313]	[145]	-5	hSpCas9	negative selection	96334
48431203	48431226	10	+	26472758	Jiyoye	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	-0.18006445992634879	[316]	[210]	-1	hSpCas9	negative selection	96335
48431231	48431254	10	+	26472758	Jiyoye	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	-0.1379226583373433	[231]	[158]	-1	hSpCas9	negative selection	96336
48420278	48420301	10	+	26472758	Jiyoye	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	-0.37848446945241165	[230]	[133]	-3	hSpCas9	negative selection	96337
48420285	48420308	10	-	26472758	Jiyoye	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.6472698045757802	[242]	[286]	5	hSpCas9	negative selection	96338
48427117	48427140	10	+	26472758	KBM7	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.46134279692174873	[102,133]	[75,79]	5	hSpCas9	negative selection	287447
48425948	48425971	10	+	26472758	KBM7	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	0.8799232983932599	[332,331]	[438,154]	8	hSpCas9	negative selection	287448
48431259	48431282	10	-	26472758	KBM7	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	-0.5673411414473359	[515,368]	[181,99]	-5	hSpCas9	negative selection	287449
48420199	48420222	10	+	26472758	KBM7	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	0.7333052273107814	[322,137]	[132,209]	7	hSpCas9	negative selection	287450
48420268	48420291	10	+	26472758	KBM7	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.863550353701435	[297,216]	[173,256]	8	hSpCas9	negative selection	287451
48420295	48420318	10	-	26472758	KBM7	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	0.7667558422259088	[537,622]	[646,311]	8	hSpCas9	negative selection	287452
48431203	48431226	10	+	26472758	KBM7	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.24128418949418262	[1521,1174]	[813,679]	2	hSpCas9	negative selection	287453
48431231	48431254	10	+	26472758	KBM7	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.38786848558124754	[984,893]	[493,652]	4	hSpCas9	negative selection	287454
48420278	48420301	10	+	26472758	KBM7	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.13587059838526044	[473,544]	[230,297]	1	hSpCas9	negative selection	287455
48420285	48420308	10	-	26472758	KBM7	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.5265333316616032	[1264,1669]	[931,1084]	6	hSpCas9	negative selection	287456
48427117	48427140	10	+	26472758	Raji	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	1.0417951937460228	[89]	[42]	8	hSpCas9	negative selection	478565
48425948	48425971	10	+	26472758	Raji	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	0.8146017861457535	[146]	[59]	7	hSpCas9	negative selection	478566
48431259	48431282	10	-	26472758	Raji	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	0.8078232535146918	[159]	[64]	7	hSpCas9	negative selection	478567
48420199	48420222	10	+	26472758	Raji	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	1.1073835353735997	[87]	[43]	8	hSpCas9	negative selection	478568
48420268	48420291	10	+	26472758	Raji	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.8808750055649197	[116]	[49]	7	hSpCas9	negative selection	478569
48420295	48420318	10	-	26472758	Raji	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	0.1648690300343596	[245]	[63]	1	hSpCas9	negative selection	478570
48431203	48431226	10	+	26472758	Raji	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	-0.32919949418650885	[876]	[161]	-3	hSpCas9	negative selection	478571
48431231	48431254	10	+	26472758	Raji	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.1328285519310628	[561]	[142]	1	hSpCas9	negative selection	478572
48420278	48420301	10	+	26472758	Raji	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.10128333583718169	[236]	[58]	0	hSpCas9	negative selection	478573
48420285	48420308	10	-	26472758	Raji	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.2488559613264798	[659]	[181]	2	hSpCas9	negative selection	478574
48427117	48427140	10	+	26472758	K562	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-1.2150128909708504	[120]	[43]	-6	hSpCas9	negative selection	669683
48425948	48425971	10	+	26472758	K562	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	-0.4210473461404257	[432]	[272]	-3	hSpCas9	negative selection	669684
48431259	48431282	10	-	26472758	K562	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	0.19605570610504786	[363]	[351]	1	hSpCas9	negative selection	669685
48420199	48420222	10	+	26472758	K562	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	-1.0143155407337217	[267]	[111]	-5	hSpCas9	negative selection	669686
48420268	48420291	10	+	26472758	K562	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.5651079259204504	[232]	[290]	4	hSpCas9	negative selection	669687
48420295	48420318	10	-	26472758	K562	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	0.6203866622666983	[392]	[509]	5	hSpCas9	negative selection	669688
48431203	48431226	10	+	26472758	K562	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.3835497983874103	[1046]	[1152]	3	hSpCas9	negative selection	669689
48431231	48431254	10	+	26472758	K562	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.41637141045574166	[710]	[800]	3	hSpCas9	negative selection	669690
48420278	48420301	10	+	26472758	K562	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.6292068463923857	[493]	[644]	5	hSpCas9	negative selection	669691
48420285	48420308	10	-	26472758	K562	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.20965330950577044	[839]	[819]	1	hSpCas9	negative selection	669692
48404914	48404937	10	+	26627737	DLD1	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.4211136182015932	[823]	[355,442,253]	4	hSpCas9	negative selection	775005
48404915	48404938	10	+	26627737	DLD1	viability	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.9329192637785594	[273]	[200,107,176]	8	hSpCas9	negative selection	775006
48420268	48420291	10	+	26627737	DLD1	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.5882655940847185	[801]	[537,398,218]	6	hSpCas9	negative selection	775007
48420283	48420306	10	+	26627737	DLD1	viability	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	-0.8414023426471522	[941]	[313,117,72]	-7	hSpCas9	negative selection	775008
48427117	48427140	10	+	26627737	DLD1	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	1.5875510319926402	[145]	[102,61,228]	9	hSpCas9	negative selection	775009
48431232	48431255	10	+	26627737	DLD1	viability	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	0.5781299922424024	[1096]	[374,531,613]	6	hSpCas9	negative selection	775010
48404914	48404937	10	+	26627737	GBM cells	viability after 5 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.5450874285729536	[422]	[315,345]	7	hSpCas9	negative selection	857320
48404915	48404938	10	+	26627737	GBM cells	viability after 5 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.6733541744705547	[189]	[171,152]	8	hSpCas9	negative selection	857321
48420268	48420291	10	+	26627737	GBM cells	viability after 5 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.7352926155280466	[470]	[407,432]	8	hSpCas9	negative selection	857322
48420283	48420306	10	+	26627737	GBM cells	viability after 5 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.4655445528345845	[263]	[259,130]	7	hSpCas9	negative selection	857323
48427117	48427140	10	+	26627737	GBM cells	viability after 5 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.25931611758768364	[221]	[144,139]	4	hSpCas9	negative selection	857324
48431232	48431255	10	+	26627737	GBM cells	viability after 5 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.13416848007014437	[793]	[381,393]	-2	hSpCas9	negative selection	857325
48404914	48404937	10	+	26627737	GBM cells	viability after 13 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.7686954571715917	[422]	[363,412]	8	hSpCas9	negative selection	939635
48404915	48404938	10	+	26627737	GBM cells	viability after 13 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.7318979357048505	[189]	[184,159]	8	hSpCas9	negative selection	939636
48420268	48420291	10	+	26627737	GBM cells	viability after 13 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.7855662457678161	[470]	[509,383]	8	hSpCas9	negative selection	939637
48420283	48420306	10	+	26627737	GBM cells	viability after 13 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.9500335139873456	[263]	[284,269]	9	hSpCas9	negative selection	939638
48427117	48427140	10	+	26627737	GBM cells	viability after 13 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.3253190175305316	[221]	[199,110]	4	hSpCas9	negative selection	939639
48431232	48431255	10	+	26627737	GBM cells	viability after 13 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.07094632986674543	[793]	[472,358]	-1	hSpCas9	negative selection	939640
48404914	48404937	10	+	26627737	GBM cells	viability after 21 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	1.0465579170626258	[422]	[481,467]	9	hSpCas9	negative selection	1021950
48404915	48404938	10	+	26627737	GBM cells	viability after 21 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	1.0688970408800054	[189]	[238,195]	9	hSpCas9	negative selection	1021951
48420268	48420291	10	+	26627737	GBM cells	viability after 21 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	1.2892854590405534	[470]	[662,590]	9	hSpCas9	negative selection	1021952
48420283	48420306	10	+	26627737	GBM cells	viability after 21 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.7507225666192544	[263]	[256,226]	7	hSpCas9	negative selection	1021953
48427117	48427140	10	+	26627737	GBM cells	viability after 21 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.43031061932209647	[221]	[161,162]	4	hSpCas9	negative selection	1021954
48431232	48431255	10	+	26627737	GBM cells	viability after 21 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.2693939535867971	[793]	[383,333]	-2	hSpCas9	negative selection	1021955
48404914	48404937	10	+	26627737	RPE1	viability after 9 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.23593864814721888	[1438]	[554,498]	1	hSpCas9	negative selection	1104265
48404915	48404938	10	+	26627737	RPE1	viability after 9 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.5885134692350491	[440]	[197,219]	4	hSpCas9	negative selection	1104266
48420268	48420291	10	+	26627737	RPE1	viability after 9 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.3138941592365685	[2525]	[509,798]	-2	hSpCas9	negative selection	1104267
48420283	48420306	10	+	26627737	RPE1	viability after 9 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	-0.5364368499249484	[1065]	[216,246]	-4	hSpCas9	negative selection	1104268
48427117	48427140	10	+	26627737	RPE1	viability after 9 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.4463778931178173	[661]	[169,128]	-3	hSpCas9	negative selection	1104269
48431232	48431255	10	+	26627737	RPE1	viability after 9 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.15206076244284095	[1850]	[438,627]	-1	hSpCas9	negative selection	1104270
48404914	48404937	10	+	26627737	RPE1	viability after 12 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.5431299556237631	[1438]	[625,496]	3	hSpCas9	negative selection	1186580
48404915	48404938	10	+	26627737	RPE1	viability after 12 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.3844062218852926	[440]	[159,148]	2	hSpCas9	negative selection	1186581
48420268	48420291	10	+	26627737	RPE1	viability after 12 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.44826481478487	[2525]	[510,482]	-3	hSpCas9	negative selection	1186582
48420283	48420306	10	+	26627737	RPE1	viability after 12 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	-0.6672818380175459	[1065]	[157,203]	-4	hSpCas9	negative selection	1186583
48427117	48427140	10	+	26627737	RPE1	viability after 12 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.8057922917159835	[661]	[75,128]	-5	hSpCas9	negative selection	1186584
48431232	48431255	10	+	26627737	RPE1	viability after 12 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	0.25765923080631525	[1850]	[408,790]	1	hSpCas9	negative selection	1186585
48404914	48404937	10	+	26627737	RPE1	viability after 15 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.8579016874764397	[1438]	[1116,371]	5	hSpCas9	negative selection	1268895
48404915	48404938	10	+	26627737	RPE1	viability after 15 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	1.009840465527456	[440]	[323,180]	6	hSpCas9	negative selection	1268896
48420268	48420291	10	+	26627737	RPE1	viability after 15 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.5306211641196821	[2525]	[457,529]	-3	hSpCas9	negative selection	1268897
48420283	48420306	10	+	26627737	RPE1	viability after 15 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	-0.0038490542683340956	[1065]	[286,313]	0	hSpCas9	negative selection	1268898
48427117	48427140	10	+	26627737	RPE1	viability after 15 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.11061707633410492	[661]	[260,88]	0	hSpCas9	negative selection	1268899
48431232	48431255	10	+	26627737	RPE1	viability after 15 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	0.3479591408471576	[1850]	[529,797]	2	hSpCas9	negative selection	1268900
48404914	48404937	10	+	26627737	RPE1	viability after 18 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.7025656750778954	[1438]	[820,429]	4	hSpCas9	negative selection	1351210
48404915	48404938	10	+	26627737	RPE1	viability after 18 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.20988676335976253	[440]	[141,132]	1	hSpCas9	negative selection	1351211
48420268	48420291	10	+	26627737	RPE1	viability after 18 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.025688332741822695	[2525]	[717,617]	0	hSpCas9	negative selection	1351212
48420283	48420306	10	+	26627737	RPE1	viability after 18 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	-0.21732884910393302	[1065]	[347,139]	-1	hSpCas9	negative selection	1351213
48427117	48427140	10	+	26627737	RPE1	viability after 18 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.8468360715011293	[661]	[108,88]	-5	hSpCas9	negative selection	1351214
48431232	48431255	10	+	26627737	RPE1	viability after 18 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	0.6331815640450398	[1850]	[417,1155]	4	hSpCas9	negative selection	1351215
48404914	48404937	10	+	26627737	HeLa	viability after 8 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	1.3845039964323425	[292]	[396,301,314]	8	hSpCas9	negative selection	1433525
48404915	48404938	10	+	26627737	HeLa	viability after 8 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	-0.5148276375367992	[492]	[231,153,86]	-5	hSpCas9	negative selection	1433526
48420268	48420291	10	+	26627737	HeLa	viability after 8 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.05103269802543331	[720]	[382,296,308]	0	hSpCas9	negative selection	1433527
48420283	48420306	10	+	26627737	HeLa	viability after 8 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.33639203913652443	[466]	[294,238,244]	3	hSpCas9	negative selection	1433528
48427117	48427140	10	+	26627737	HeLa	viability after 8 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.3136801704909653	[378]	[121,85,183]	-3	hSpCas9	negative selection	1433529
48431232	48431255	10	+	26627737	HeLa	viability after 8 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.35336140636039604	[779]	[249,313,231]	-3	hSpCas9	negative selection	1433530
48404914	48404937	10	+	26627737	HeLa	viability after 12 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	1.5335722821617221	[292]	[208,364,471]	8	hSpCas9	negative selection	1515840
48404915	48404938	10	+	26627737	HeLa	viability after 12 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	-0.1392977386165151	[492]	[206,218,125]	-1	hSpCas9	negative selection	1515841
48420268	48420291	10	+	26627737	HeLa	viability after 12 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.32953889711213946	[720]	[83,339,271]	-3	hSpCas9	negative selection	1515842
48420283	48420306	10	+	26627737	HeLa	viability after 12 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	1.1265231029290765	[466]	[410,428,422]	7	hSpCas9	negative selection	1515843
48427117	48427140	10	+	26627737	HeLa	viability after 12 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.0745394725825253	[378]	[221,85,146]	0	hSpCas9	negative selection	1515844
48431232	48431255	10	+	26627737	HeLa	viability after 12 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.5514031607749834	[779]	[277,177,209]	-5	hSpCas9	negative selection	1515845
48404914	48404937	10	+	26627737	HeLa	viability after 15 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	1.8326444362514263	[292]	[283,475,523]	9	hSpCas9	negative selection	1598155
48404915	48404938	10	+	26627737	HeLa	viability after 15 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	-0.6942378293967092	[492]	[115,146,107]	-6	hSpCas9	negative selection	1598156
48420268	48420291	10	+	26627737	HeLa	viability after 15 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.0884814212842685	[720]	[132,282,539]	0	hSpCas9	negative selection	1598157
48420283	48420306	10	+	26627737	HeLa	viability after 15 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.8350037487230539	[466]	[226,257,549]	6	hSpCas9	negative selection	1598158
48427117	48427140	10	+	26627737	HeLa	viability after 15 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.2930341957567363	[378]	[242,211,104]	2	hSpCas9	negative selection	1598159
48431232	48431255	10	+	26627737	HeLa	viability after 15 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.5713512680213539	[779]	[143,235,265]	-5	hSpCas9	negative selection	1598160
48404914	48404937	10	+	26627737	HeLa	viability after 18 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	1.8149627472378935	[292]	[186,385,523]	9	hSpCas9	negative selection	1680470
48404915	48404938	10	+	26627737	HeLa	viability after 18 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	-0.7123371676066044	[492]	[72,123,107]	-6	hSpCas9	negative selection	1680471
48420268	48420291	10	+	26627737	HeLa	viability after 18 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.07630104707473173	[720]	[85,231,539]	0	hSpCas9	negative selection	1680472
48420283	48420306	10	+	26627737	HeLa	viability after 18 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.8545227118089218	[466]	[156,218,549]	6	hSpCas9	negative selection	1680473
48427117	48427140	10	+	26627737	HeLa	viability after 18 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.28485709007426896	[378]	[162,172,104]	2	hSpCas9	negative selection	1680474
48431232	48431255	10	+	26627737	HeLa	viability after 18 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.6041747269354572	[779]	[89,191,265]	-5	hSpCas9	negative selection	1680475
48404914	48404937	10	+	26627737	HCT116	viability after 6 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.5341332930254261	[922]	[212,37]	-3	hSpCas9	negative selection	1762785
48404915	48404938	10	+	26627737	HCT116	viability after 6 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.5618423863230648	[314]	[7,108]	3	hSpCas9	negative selection	1762786
48420268	48420291	10	+	26627737	HCT116	viability after 6 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.33661967811071003	[1443]	[441,200]	2	hSpCas9	negative selection	1762787
48420283	48420306	10	+	26627737	HCT116	viability after 6 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	-0.06762674811625324	[869]	[290,41]	0	hSpCas9	negative selection	1762788
48427117	48427140	10	+	26627737	HCT116	viability after 6 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-3.487409063428535	[400]	[13,0]	-9	hSpCas9	negative selection	1762789
48431232	48431255	10	+	26627737	HCT116	viability after 6 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.7540454429195135	[1298]	[142,108]	-4	hSpCas9	negative selection	1762790
48404914	48404937	10	+	26627737	HCT116	viability after 8 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.21036774511133793	[543]	[456,286,298]	2	hSpCas9	negative selection	1845100
48404915	48404938	10	+	26627737	HCT116	viability after 8 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	1.52472927471128	[105]	[143,211,147]	9	hSpCas9	negative selection	1845101
48420268	48420291	10	+	26627737	HCT116	viability after 8 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.7574937811450944	[538]	[572,385,547]	7	hSpCas9	negative selection	1845102
48420283	48420306	10	+	26627737	HCT116	viability after 8 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.21300721787316113	[394]	[273,210,271]	2	hSpCas9	negative selection	1845103
48427117	48427140	10	+	26627737	HCT116	viability after 8 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.36611864041710607	[168]	[110,135,112]	4	hSpCas9	negative selection	1845104
48431232	48431255	10	+	26627737	HCT116	viability after 8 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.3680183310775367	[589]	[245,206,301]	-4	hSpCas9	negative selection	1845105
48404914	48404937	10	+	26627737	HCT116	viability after 9 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.26413276604693714	[922]	[307,123]	-2	hSpCas9	negative selection	1927415
48404915	48404938	10	+	26627737	HCT116	viability after 9 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	-0.2928694733675178	[314]	[90,50]	-2	hSpCas9	negative selection	1927416
48420268	48420291	10	+	26627737	HCT116	viability after 9 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.6299597214488732	[1443]	[303,827]	4	hSpCas9	negative selection	1927417
48420283	48420306	10	+	26627737	HCT116	viability after 9 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.09048364509889861	[869]	[348,166]	0	hSpCas9	negative selection	1927418
48427117	48427140	10	+	26627737	HCT116	viability after 9 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-1.7916303394943012	[400]	[64,3]	-8	hSpCas9	negative selection	1927419
48431232	48431255	10	+	26627737	HCT116	viability after 9 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.8209683825754381	[1298]	[297,115]	-5	hSpCas9	negative selection	1927420
48404914	48404937	10	+	26627737	HCT116	viability after 12 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.034340992332224984	[543]	[254,348,278]	0	hSpCas9	negative selection	2009730
48404915	48404938	10	+	26627737	HCT116	viability after 12 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	1.2473814939925225	[105]	[135,155,104]	8	hSpCas9	negative selection	2009731
48420268	48420291	10	+	26627737	HCT116	viability after 12 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.3412263475068227	[538]	[380,334,357]	3	hSpCas9	negative selection	2009732
48420283	48420306	10	+	26627737	HCT116	viability after 12 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.01866648289738676	[394]	[259,189,175]	0	hSpCas9	negative selection	2009733
48427117	48427140	10	+	26627737	HCT116	viability after 12 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.3970220820964112	[168]	[38,73,91]	-4	hSpCas9	negative selection	2009734
48431232	48431255	10	+	26627737	HCT116	viability after 12 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.765991163437382	[589]	[145,215,188]	-7	hSpCas9	negative selection	2009735
48404914	48404937	10	+	26627737	HCT116	viability after 15 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.2629596428986113	[543]	[232,304,239]	-3	hSpCas9	negative selection	2092045
48404915	48404938	10	+	26627737	HCT116	viability after 15 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	1.6732010514982996	[105]	[154,255,166]	9	hSpCas9	negative selection	2092046
48420268	48420291	10	+	26627737	HCT116	viability after 15 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.8155214737298047	[538]	[899,351,426]	7	hSpCas9	negative selection	2092047
48420283	48420306	10	+	26627737	HCT116	viability after 15 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.3379980594979286	[394]	[333,248,282]	3	hSpCas9	negative selection	2092048
48427117	48427140	10	+	26627737	HCT116	viability after 15 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.1975364744621897	[168]	[183,68,89]	2	hSpCas9	negative selection	2092049
48431232	48431255	10	+	26627737	HCT116	viability after 15 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.7478663913407321	[589]	[224,169,212]	-6	hSpCas9	negative selection	2092050
48404914	48404937	10	+	26627737	HCT116	viability after 18 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.139219925330633	[543]	[392,101,229]	-1	hSpCas9	negative selection	2174360
48404915	48404938	10	+	26627737	HCT116	viability after 18 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	2.253023181945327	[105]	[124,308,296]	9	hSpCas9	negative selection	2174361
48420268	48420291	10	+	26627737	HCT116	viability after 18 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.29430518471221734	[538]	[473,235,250]	2	hSpCas9	negative selection	2174362
48420283	48420306	10	+	26627737	HCT116	viability after 18 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	-0.03278218977320957	[394]	[310,92,160]	0	hSpCas9	negative selection	2174363
48427117	48427140	10	+	26627737	HCT116	viability after 18 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.30581221111137213	[168]	[68,113,119]	2	hSpCas9	negative selection	2174364
48431232	48431255	10	+	26627737	HCT116	viability after 18 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-1.0085268338408238	[589]	[197,112,114]	-7	hSpCas9	negative selection	2174365
48401726	48401749	10	-	24336569	HL60	viability	TTAAATTCTGATATCGTTTCAGG	MAPK8	ENSG00000107643	0.9522565172151048	[147]	[605]	7	hSpCas9	negative selection	2276160
48401751	48401774	10	-	24336569	HL60	viability	CCTTGAGCTCCTGAGCCTATAGG	MAPK8	ENSG00000107643	0.6762703586318818	[599]	[2028]	6	hSpCas9	negative selection	2276161
48401761	48401784	10	+	24336569	HL60	viability	CAGGAGCTCAAGGAATAGTATGG	MAPK8	ENSG00000107643	0.39990093947435323	[812]	[2269]	3	hSpCas9	negative selection	2276162
48404866	48404889	10	-	24336569	HL60	viability	TGCAACATTTCTTTCAAGAATGG	MAPK8	ENSG00000107643	0.5663060403920743	[426]	[1337]	5	hSpCas9	negative selection	2276163
48404903	48404926	10	-	24336569	HL60	viability	GAGTCTGATTCTGAAATGGTCGG	MAPK8	ENSG00000107643	0.11467842154972674	[514]	[1179]	1	hSpCas9	negative selection	2276164
48404914	48404937	10	+	24336569	HL60	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.15977614869290524	[955]	[2259]	1	hSpCas9	negative selection	2276165
48404929	48404952	10	-	24336569	HL60	viability	TAGCTCTCTGTAGGCCCGCTTGG	MAPK8	ENSG00000107643	-0.36525706662948737	[797]	[1310]	-3	hSpCas9	negative selection	2276166
48404938	48404961	10	-	24336569	HL60	viability	CATAAGAACTAGCTCTCTGTAGG	MAPK8	ENSG00000107643	0.35528078821029385	[436]	[1182]	3	hSpCas9	negative selection	2276167
48409906	48409929	10	-	24336569	HL60	viability	AATTCTTCTAGGGATTTCTGTGG	MAPK8	ENSG00000107643	0.2216348021870354	[508]	[1255]	2	hSpCas9	negative selection	2276168
48409916	48409939	10	-	24336569	HL60	viability	CACATCTTGAAATTCTTCTAGGG	MAPK8	ENSG00000107643	-0.16873093684654678	[689]	[1298]	-1	hSpCas9	negative selection	2276169
48401726	48401749	10	-	24336569	KBM7	viability	TTAAATTCTGATATCGTTTCAGG	MAPK8	ENSG00000107643	1.0395833778219803	[266]	[1496]	8	hSpCas9	negative selection	2343337
48401751	48401774	10	-	24336569	KBM7	viability	CCTTGAGCTCCTGAGCCTATAGG	MAPK8	ENSG00000107643	0.11352496307945548	[690]	[2038]	1	hSpCas9	negative selection	2343338
48401761	48401784	10	+	24336569	KBM7	viability	CAGGAGCTCAAGGAATAGTATGG	MAPK8	ENSG00000107643	0.0453019538555699	[716]	[2017]	0	hSpCas9	negative selection	2343339
48404866	48404889	10	-	24336569	KBM7	viability	TGCAACATTTCTTTCAAGAATGG	MAPK8	ENSG00000107643	0.5486784017653007	[385]	[1539]	5	hSpCas9	negative selection	2343340
48404903	48404926	10	-	24336569	KBM7	viability	GAGTCTGATTCTGAAATGGTCGG	MAPK8	ENSG00000107643	0.14052985948913777	[457]	[1376]	1	hSpCas9	negative selection	2343341
48404914	48404937	10	+	24336569	KBM7	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.1510894213293692	[872]	[2643]	1	hSpCas9	negative selection	2343342
48404929	48404952	10	-	24336569	KBM7	viability	TAGCTCTCTGTAGGCCCGCTTGG	MAPK8	ENSG00000107643	0.14966163395071042	[662]	[2005]	1	hSpCas9	negative selection	2343343
48404938	48404961	10	-	24336569	KBM7	viability	CATAAGAACTAGCTCTCTGTAGG	MAPK8	ENSG00000107643	0.7917238413992115	[520]	[2459]	7	hSpCas9	negative selection	2343344
48409906	48409929	10	-	24336569	KBM7	viability	AATTCTTCTAGGGATTTCTGTGG	MAPK8	ENSG00000107643	0.43377630695249847	[208]	[769]	4	hSpCas9	negative selection	2343345
48409916	48409939	10	-	24336569	KBM7	viability	CACATCTTGAAATTCTTCTAGGG	MAPK8	ENSG00000107643	1.2827465212237794	[293]	[1950]	9	hSpCas9	negative selection	2343346
48430135	48430158	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCACTGCTCTCCAGCCTGG	MAPK8	ENSG00000107643	2.551248217728088	[38,37]	[48,49]	8	dCas9-VP64	positive selection	2422345
48401164	48401187	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGTCTCATTTAGTGCCAAGTGG	MAPK8	ENSG00000107643	0.7991424565099805	[131,266]	[15,141]	3	dCas9-VP64	positive selection	2431039
48401247	48401270	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATAAGCACATGAGAAAGACTGG	MAPK8	ENSG00000107643	2.179355706852384	[98,224]	[113,214]	7	dCas9-VP64	positive selection	2431040
48401364	48401387	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTGGTAACTTCTAGATTGGAGG	MAPK8	ENSG00000107643	1.3753389238405045	[138,209]	[41,162]	5	dCas9-VP64	positive selection	2431041
48355351	48355374	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TACAAAAAATTAGCCGGGTGTAG	MAPK8	ENSG00000107643	0.005790697324581817	[8,20]	[2,2]	0	dCas9-VP64	positive selection	2434850
48317295	48317318	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCGGGAGGCTGGAG	MAPK8	ENSG00000107643	-0.4892893999709095	[44,388]	[14,54]	-2	dCas9-VP64	positive selection	2465809
48320040	48320063	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCCCAACTACTGGG	MAPK8	ENSG00000107643	-0.8834461465924942	[182,246]	[29,20]	-5	dCas9-VP64	positive selection	2476812
48430135	48430158	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCACTGCTCTCCAGCCTGG	MAPK8	ENSG00000107643	-0.5010437822197633	[153,115]	[33,26]	-5	dCas9-VP64	positive selection	2517600
48401164	48401187	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGTCTCATTTAGTGCCAAGTGG	MAPK8	ENSG00000107643	-0.5363869483160398	[119,356]	[22,80]	-5	dCas9-VP64	positive selection	2526294
48401247	48401270	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATAAGCACATGAGAAAGACTGG	MAPK8	ENSG00000107643	1.0286719104168374	[389,261]	[213,221]	6	dCas9-VP64	positive selection	2526295
48401364	48401387	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTGGTAACTTCTAGATTGGAGG	MAPK8	ENSG00000107643	0.1973284867482492	[195,404]	[77,142]	1	dCas9-VP64	positive selection	2526296
48355351	48355374	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TACAAAAAATTAGCCGGGTGTAG	MAPK8	ENSG00000107643	1.0784968234287284	[5,24]	[2,16]	7	dCas9-VP64	positive selection	2530105
48317295	48317318	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCGGGAGGCTGGAG	MAPK8	ENSG00000107643	-0.16148281958930955	[134,276]	[52,65]	-1	dCas9-VP64	positive selection	2561064
48320040	48320063	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCCCAACTACTGGG	MAPK8	ENSG00000107643	0.6336599384503461	[246,243]	[91,154]	5	dCas9-VP64	positive selection	2572067
48404915	48404938	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.26144323735881253	[3,3]	[3,3]	5	hSpCas9	positive selection	3001277
48410147	48410170	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTCTGCTGGAATTATTCATCGG	MAPK8	ENSG00000107643	0.48054762362284986	[4,4]	[5,5]	8	hSpCas9	positive selection	3001278
48401751	48401774	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTGAGCTCCTGAGCCTATAGG	MAPK8	ENSG00000107643	-0.7483326200437369	[3,3]	[2,0]	-8	hSpCas9	positive selection	3001279
48404907	48404930	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.06940196666495915	[4,4]	[4,2]	1	hSpCas9	positive selection	3001280
48404915	48404938	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.6045682894491987	[3,3]	[2,4]	8	hSpCas9	positive selection	3069135
48410147	48410170	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTCTGCTGGAATTATTCATCGG	MAPK8	ENSG00000107643	0.3673917488723847	[4,4]	[5,3]	6	hSpCas9	positive selection	3069136
48401751	48401774	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTGAGCTCCTGAGCCTATAGG	MAPK8	ENSG00000107643	0.10760507770926991	[3,3]	[2,1]	2	hSpCas9	positive selection	3069137
48404907	48404930	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.5581569694062223	[4,4]	[4,4]	8	hSpCas9	positive selection	3069138
48420222	48420245		-	24336571	A375	resistance to PLX after 7 days	AAAACTCGTTCCTGCAGTCCTGG	MAPK8	ENSG00000107643	0.03587328554037361	[65,63]	[65,65]	1	hSpCas9	positive selection	3126412
48409917	48409940		-	24336571	A375	resistance to PLX after 7 days	ACACATCTTGAAATTCTTCTAGG	MAPK8	ENSG00000107643	0.18145792294233964	[36,35]	[43,37]	5	hSpCas9	positive selection	3126413
48409887	48409910		-	24336571	A375	resistance to PLX after 7 days	GTGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	-0.19029899925086974	[18,21]	[16,18]	-6	hSpCas9	positive selection	3126414
48420268	48420291		+	24336571	A375	resistance to PLX after 7 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.01130312674290801	[55,56]	[53,57]	0	hSpCas9	positive selection	3126415
48420222	48420245		-	24336571	A375	resistance to PLX after 14 days	AAAACTCGTTCCTGCAGTCCTGG	MAPK8	ENSG00000107643	-0.0853852852981909	[68,77]	[31,31]	-1	hSpCas9	positive selection	3184205
48409917	48409940		-	24336571	A375	resistance to PLX after 14 days	ACACATCTTGAAATTCTTCTAGG	MAPK8	ENSG00000107643	0.1461098282869977	[45,43]	[24,20]	1	hSpCas9	positive selection	3184206
48409887	48409910		-	24336571	A375	resistance to PLX after 14 days	GTGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	0.004111217185578497	[18,17]	[7,7]	0	hSpCas9	positive selection	3184207
48420268	48420291		+	24336571	A375	resistance to PLX after 14 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.08183997972635382	[49,57]	[22,29]	0	hSpCas9	positive selection	3184208
48420222	48420245		-	24336571	A375	viability after 7 days	AAAACTCGTTCCTGCAGTCCTGG	MAPK8	ENSG00000107643	-0.13636522745238278	[74]	[65,63]	-2	hSpCas9	negative selection	3241998
48409917	48409940		-	24336571	A375	viability after 7 days	ACACATCTTGAAATTCTTCTAGG	MAPK8	ENSG00000107643	-0.8319662252270583	[67]	[36,35]	-8	hSpCas9	negative selection	3241999
48409887	48409910		-	24336571	A375	viability after 7 days	GTGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	-0.08927153075007577	[22]	[18,21]	-1	hSpCas9	negative selection	3242000
48420268	48420291		+	24336571	A375	viability after 7 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.2940429567169893	[47]	[55,56]	4	hSpCas9	negative selection	3242001
48420222	48420245		-	24336571	A375	viability after 14 days	AAAACTCGTTCCTGCAGTCCTGG	MAPK8	ENSG00000107643	0.0590453896325136	[74]	[68,77]	0	hSpCas9	negative selection	3299791
48409917	48409940		-	24336571	A375	viability after 14 days	ACACATCTTGAAATTCTTCTAGG	MAPK8	ENSG00000107643	-0.5062322272108064	[67]	[45,43]	-6	hSpCas9	negative selection	3299792
48409887	48409910		-	24336571	A375	viability after 14 days	GTGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	-0.23381151286084778	[22]	[18,17]	-3	hSpCas9	negative selection	3299793
48420268	48420291		+	24336571	A375	viability after 14 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.23572934034283932	[47]	[49,57]	3	hSpCas9	negative selection	3299794
48404914	48404937	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.30312990105895976	[123,123]	[0,0]	1	hSpCas9	positive selection	3378507
48404907	48404930	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	1.6426163673306269	[48,48]	[0,0]	6	hSpCas9	positive selection	3378508
48410021	48410044	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.39934521631826303	[115,115]	[0,0]	2	hSpCas9	positive selection	3378509
48404914	48404937	10	+	26780180	HT29	viability (Avana library 4 designs)	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.579615789981676	[]	[]	-8	hSpCas9	negative selection	3438923
48410146	48410169	10	+	26780180	HT29	viability (Avana library 4 designs)	ATTCTGCTGGAATTATTCATCGG	MAPK8	ENSG00000107643	0.431926916295978	[]	[]	1	hSpCas9	negative selection	3438924
48401751	48401774	10	-	26780180	HT29	viability (Avana library 4 designs)	CCTTGAGCTCCTGAGCCTATAGG	MAPK8	ENSG00000107643	0.484323261178896	[]	[]	1	hSpCas9	negative selection	3438925
48404907	48404930	10	-	26780180	HT29	viability (Avana library 4 designs)	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.143625817282952	[]	[]	0	hSpCas9	negative selection	3438926
48404914	48404937	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.215963176291242	[]	[]	0	hSpCas9	negative selection	3528414
48410146	48410169	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTCTGCTGGAATTATTCATCGG	MAPK8	ENSG00000107643	-8.93308353220517	[]	[]	-7	hSpCas9	negative selection	3528415
48404907	48404930	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	1.68136812596422	[]	[]	2	hSpCas9	negative selection	3528416
48401751	48401774	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTGAGCTCCTGAGCCTATAGG	MAPK8	ENSG00000107643	1.5719553636714	[]	[]	2	hSpCas9	negative selection	3528417
48401736	48401759	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATCAGAATTTAAAACCTATAGG	MAPK8	ENSG00000107643	-6.38359954509846	[]	[]	-6	hSpCas9	negative selection	3528418
48410104	48410127	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCATCTGATAGAGAAGGTAGG	MAPK8	ENSG00000107643	4.03725888905704	[]	[]	6	hSpCas9	negative selection	3528419
48404914	48404937	10	+	26780180	A375	viability (Avana lentiGuide)	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-3.78267287476872	[]	[]	-6	hSpCas9	negative selection	3637073
48410146	48410169	10	+	26780180	A375	viability (Avana lentiGuide)	ATTCTGCTGGAATTATTCATCGG	MAPK8	ENSG00000107643	-6.30018983283213	[]	[]	-9	hSpCas9	negative selection	3637074
48404907	48404930	10	-	26780180	A375	viability (Avana lentiGuide)	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-1.73712405167866	[]	[]	-3	hSpCas9	negative selection	3637075
48401751	48401774	10	-	26780180	A375	viability (Avana lentiGuide)	CCTTGAGCTCCTGAGCCTATAGG	MAPK8	ENSG00000107643	-6.90652321404113	[]	[]	-9	hSpCas9	negative selection	3637076
48401736	48401759	10	+	26780180	A375	viability (Avana lentiGuide)	TATCAGAATTTAAAACCTATAGG	MAPK8	ENSG00000107643	-8.36286253536741	[]	[]	-9	hSpCas9	negative selection	3637077
48410104	48410127	10	-	26780180	A375	viability (Avana lentiGuide)	CAGCATCTGATAGAGAAGGTAGG	MAPK8	ENSG00000107643	-1.36689375128533	[]	[]	-2	hSpCas9	negative selection	3637078
48404914	48404937	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.11269791952424008	[5]	[5,3]	-2	hSpCas9	positive selection	3745732
48410146	48410169	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTCTGCTGGAATTATTCATCGG	MAPK8	ENSG00000107643	-0.29155588808919153	[7]	[5,5]	-4	hSpCas9	positive selection	3745733
48404907	48404930	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.06609361147277601	[5]	[5,5]	1	hSpCas9	positive selection	3745734
48401751	48401774	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTGAGCTCCTGAGCCTATAGG	MAPK8	ENSG00000107643	0.2107093082966881	[4]	[4,5]	6	hSpCas9	positive selection	3745735
48401736	48401759	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATCAGAATTTAAAACCTATAGG	MAPK8	ENSG00000107643	-1.0333468395793646	[9]	[3,4]	-9	hSpCas9	positive selection	3745736
48410104	48410127	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCATCTGATAGAGAAGGTAGG	MAPK8	ENSG00000107643	0.1897253315355505	[4]	[5,4]	5	hSpCas9	positive selection	3745737
48404914	48404937	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.29918333115552664	[5]	[5,5]	8	hSpCas9	positive selection	3854339
48410146	48410169	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTCTGCTGGAATTATTCATCGG	MAPK8	ENSG00000107643	0.2793402433237535	[6]	[7,5]	7	hSpCas9	positive selection	3854340
48404907	48404930	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.22952307084741586	[5]	[5,5]	6	hSpCas9	positive selection	3854341
48401751	48401774	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTGAGCTCCTGAGCCTATAGG	MAPK8	ENSG00000107643	0.29585951523610915	[4]	[5,4]	8	hSpCas9	positive selection	3854342
48401736	48401759	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATCAGAATTTAAAACCTATAGG	MAPK8	ENSG00000107643	0.6043140639177909	[4]	[6,6]	9	hSpCas9	positive selection	3854343
48410104	48410127	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCATCTGATAGAGAAGGTAGG	MAPK8	ENSG00000107643	-0.18150766410768035	[5]	[3,3]	-3	hSpCas9	positive selection	3854344
48404914	48404937	10	+	26780180	A375	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.619186613817659	[]	[]	2	hSpCas9	negative selection	3959861
48410021	48410044	10	+	26780180	A375	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	1.49160019409774	[]	[]	8	hSpCas9	negative selection	3959862
48404907	48404930	10	-	26780180	A375	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.52942072114472	[]	[]	1	hSpCas9	negative selection	3959863
48420254	48420277	10	-	26780180	A375	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	0.970418767713682	[]	[]	4	hSpCas9	negative selection	3959864
48420268	48420291	10	+	26780180	A375	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.521319592593778	[]	[]	1	hSpCas9	negative selection	3959865
48410060	48410083	10	+	26780180	A375	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	1.1400294799959	[]	[]	6	hSpCas9	negative selection	3959866
48404914	48404937	10	+	26780180	HT29	viability (GeCKOv2 library)	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	1.0290194385428	[]	[]	5	hSpCas9	negative selection	4067827
48410021	48410044	10	+	26780180	HT29	viability (GeCKOv2 library)	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.528896983400092	[]	[]	1	hSpCas9	negative selection	4067828
48404907	48404930	10	-	26780180	HT29	viability (GeCKOv2 library)	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	1.03558805715177	[]	[]	5	hSpCas9	negative selection	4067829
48420254	48420277	10	-	26780180	HT29	viability (GeCKOv2 library)	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	0.688070981512983	[]	[]	2	hSpCas9	negative selection	4067830
48420268	48420291	10	+	26780180	HT29	viability (GeCKOv2 library)	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.683384984777044	[]	[]	2	hSpCas9	negative selection	4067831
48410060	48410083	10	+	26780180	HT29	viability (GeCKOv2 library)	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.414851737983153	[]	[]	1	hSpCas9	negative selection	4067832
48420222	48420245	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAACTCGTTCCTGCAGTCCTGG	MAPK8	ENSG00000107643	0.17480098515089915	[6]	[4,4]	4	hSpCas9	positive selection	4150632
48409917	48409940	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACACATCTTGAAATTCTTCTAGG	MAPK8	ENSG00000107643	0.23017362131823804	[5]	[3,4]	6	hSpCas9	positive selection	4150633
48409887	48409910	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	0.04120141191560095	[4]	[3,2]	1	hSpCas9	positive selection	4150634
48420268	48420291	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.22410783127462042	[5]	[4,4]	5	hSpCas9	positive selection	4150635
48420222	48420245	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAACTCGTTCCTGCAGTCCTGG	MAPK8	ENSG00000107643	0.20887077996739933	[6]	[5,5,4,0]	1	hSpCas9	positive selection	4214654
48409917	48409940	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACACATCTTGAAATTCTTCTAGG	MAPK8	ENSG00000107643	0.9031237849489865	[6]	[5,4,4,4]	6	hSpCas9	positive selection	4214655
48409887	48409910	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	0.1986202980335815	[4]	[4,3,3,0]	1	hSpCas9	positive selection	4214656
48420268	48420291	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.07702749460965619	[5]	[1,4,3,0]	0	hSpCas9	positive selection	4214657
48420268	48420291	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.18634866482754778	[3]	[3,1]	-4	hSpCas9	positive selection	4281942
48420254	48420277	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	0.26416085104708503	[4]	[3,3]	5	hSpCas9	positive selection	4281943
48410060	48410083	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.16480774788232946	[2]	[2,1]	3	hSpCas9	positive selection	4281944
48404914	48404937	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.32559850195055584	[2]	[2,0]	-6	hSpCas9	positive selection	4346200
48404907	48404930	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.5627911509774889	[1]	[1,2]	9	hSpCas9	positive selection	4346201
48410021	48410044	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.12670773416990477	[2]	[3,1]	2	hSpCas9	positive selection	4346202
48404916	48404938	10	+	27760321	OCIAML3	viability	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	-0.040293453138039614	[676,499]	[390,511]	0	hSpCas9	negative selection	4416767
48409887	48409909	10	-	27760321	OCIAML3	viability	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	-3.3775555163325386	[9,15]	[0,0]	-9	hSpCas9	negative selection	4416768
48410022	48410044	10	+	27760321	OCIAML3	viability	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	1.202871689362944	[12,11]	[38,0]	9	hSpCas9	negative selection	4416769
48410066	48410088	10	-	27760321	OCIAML3	viability	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.12668278223800022	[913,788]	[606,878]	1	hSpCas9	negative selection	4416770
48420254	48420276	10	-	27760321	OCIAML3	viability	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.7000484434361067	[118,66]	[29,61]	-6	hSpCas9	negative selection	4416771
48404916	48404938	10	+	27760321	OCIAML2	viability	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.33474230857316967	[676,499]	[537,669]	4	hSpCas9	negative selection	4500230
48409887	48409909	10	-	27760321	OCIAML2	viability	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	0.14210468680354893	[9,15]	[10,12]	1	hSpCas9	negative selection	4500231
48410022	48410044	10	+	27760321	OCIAML2	viability	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.30033593500947653	[12,11]	[8,16]	4	hSpCas9	negative selection	4500232
48410066	48410088	10	-	27760321	OCIAML2	viability	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.02766757523927832	[913,788]	[622,801]	0	hSpCas9	negative selection	4500233
48420254	48420276	10	-	27760321	OCIAML2	viability	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	0.07351897268191587	[118,66]	[71,84]	0	hSpCas9	negative selection	4500234
48404916	48404938	10	+	27760321	MV411	viability	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.7845089322198612	[676,499]	[755,522]	6	hSpCas9	negative selection	4583693
48409887	48409909	10	-	27760321	MV411	viability	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	-3.1324769474178566	[9,15]	[0,0]	-9	hSpCas9	negative selection	4583694
48410022	48410044	10	+	27760321	MV411	viability	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-3.0441783981791195	[12,11]	[0,0]	-9	hSpCas9	negative selection	4583695
48410066	48410088	10	-	27760321	MV411	viability	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.5816782826207908	[913,788]	[882,771]	4	hSpCas9	negative selection	4583696
48420254	48420276	10	-	27760321	MV411	viability	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.4837834639980181	[118,66]	[70,0]	-3	hSpCas9	negative selection	4583697
48404916	48404938	10	+	27760321	HL60	viability	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.3783823726717416	[676,499]	[510,733]	5	hSpCas9	negative selection	4667156
48409887	48409909	10	-	27760321	HL60	viability	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	-0.23073060737651652	[9,15]	[0,17]	-3	hSpCas9	negative selection	4667157
48410022	48410044	10	+	27760321	HL60	viability	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.8434703664986456	[12,11]	[28,6]	8	hSpCas9	negative selection	4667158
48410066	48410088	10	-	27760321	HL60	viability	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.40656229275654165	[913,788]	[934,902]	5	hSpCas9	negative selection	4667159
48420254	48420276	10	-	27760321	HL60	viability	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.1611924802650817	[118,66]	[69,62]	-2	hSpCas9	negative selection	4667160
48404916	48404938	10	+	27760321	HT1080	viability	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.7842413148558673	[499,389]	[479,113]	4	hSpCas9	negative selection	4750619
48409887	48409909	10	-	27760321	HT1080	viability	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	-2.5337600873754464	[15,12]	[0,0]	-7	hSpCas9	negative selection	4750620
48410022	48410044	10	+	27760321	HT1080	viability	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-2.137477237836361	[11,9]	[0,0]	-6	hSpCas9	negative selection	4750621
48410066	48410088	10	-	27760321	HT1080	viability	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.7175989915776201	[788,615]	[390,535]	4	hSpCas9	negative selection	4750622
48420254	48420276	10	-	27760321	HT1080	viability	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.8211413483608454	[66,51]	[0,26]	-3	hSpCas9	negative selection	4750623
48404916	48404938	10	+	27760321	HT29	viability after 7 days	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.5156519356816138	[499,389]	[933,807,729]	7	hSpCas9	negative selection	4834082
48409887	48409909	10	-	27760321	HT29	viability after 7 days	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	0.7545601488598397	[15,12]	[37,10,45]	9	hSpCas9	negative selection	4834083
48410022	48410044	10	+	27760321	HT29	viability after 7 days	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.940384977541803	[11,9]	[12,2,6]	-8	hSpCas9	negative selection	4834084
48410066	48410088	10	-	27760321	HT29	viability after 7 days	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.277758602760081	[788,615]	[1445,1095,800]	4	hSpCas9	negative selection	4834085
48420254	48420276	10	-	27760321	HT29	viability after 7 days	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	0.2876216935042386	[66,51]	[187,62,43]	4	hSpCas9	negative selection	4834086
48404916	48404938	10	+	27760321	HT29	viability after 25 days	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	1.050051482837282	[499,389]	[840,1299,1026]	9	hSpCas9	negative selection	4917545
48409887	48409909	10	-	27760321	HT29	viability after 25 days	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	0.4894499449629599	[15,12]	[24,19,24]	5	hSpCas9	negative selection	4917546
48410022	48410044	10	+	27760321	HT29	viability after 25 days	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.5286796018742059	[11,9]	[34,4,12]	6	hSpCas9	negative selection	4917547
48410066	48410088	10	-	27760321	HT29	viability after 25 days	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.8215133531808058	[788,615]	[1501,1320,1426]	8	hSpCas9	negative selection	4917548
48420254	48420276	10	-	27760321	HT29	viability after 25 days	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	0.949163409879278	[66,51]	[132,149,107]	9	hSpCas9	negative selection	4917549
48404916	48404938	10	+	27760321	HT29	viability after 22 days	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.5795712470666539	[499,389]	[548,1012,749]	6	hSpCas9	negative selection	5001008
48409887	48409909	10	-	27760321	HT29	viability after 22 days	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	-1.3403630104117452	[15,12]	[1,14,2]	-7	hSpCas9	negative selection	5001009
48410022	48410044	10	+	27760321	HT29	viability after 22 days	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	1.9919126578971564	[11,9]	[72,2,75]	9	hSpCas9	negative selection	5001010
48410066	48410088	10	-	27760321	HT29	viability after 22 days	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.7024067246929008	[788,615]	[1430,1060,1470]	7	hSpCas9	negative selection	5001011
48420254	48420276	10	-	27760321	HT29	viability after 22 days	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	1.3658546856710712	[66,51]	[351,93,79]	9	hSpCas9	negative selection	5001012
48404916	48404938	10	+	27760321	HT29	viability after 19 days	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.5189285757757498	[499,389]	[805,707,682]	5	hSpCas9	negative selection	5084471
48409887	48409909	10	-	27760321	HT29	viability after 19 days	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	0.13488816053644825	[15,12]	[2,0,47]	1	hSpCas9	negative selection	5084472
48410022	48410044	10	+	27760321	HT29	viability after 19 days	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-1.7344627576435787	[11,9]	[8,0,1]	-7	hSpCas9	negative selection	5084473
48410066	48410088	10	-	27760321	HT29	viability after 19 days	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.7216395843801803	[788,615]	[1095,1101,1735]	7	hSpCas9	negative selection	5084474
48420254	48420276	10	-	27760321	HT29	viability after 19 days	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	1.365532654579039	[66,51]	[118,95,299]	9	hSpCas9	negative selection	5084475
48404916	48404938	10	+	27760321	HT29	viability after 16 days	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.7534270190443848	[499,389]	[809,835,868]	8	hSpCas9	negative selection	5167934
48409887	48409909	10	-	27760321	HT29	viability after 16 days	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	0.8509170225303335	[15,12]	[33,45,7]	8	hSpCas9	negative selection	5167935
48410022	48410044	10	+	27760321	HT29	viability after 16 days	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.1819666653454437	[11,9]	[0,0,29]	-2	hSpCas9	negative selection	5167936
48410066	48410088	10	-	27760321	HT29	viability after 16 days	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.42916977686331437	[788,615]	[1338,912,952]	5	hSpCas9	negative selection	5167937
48420254	48420276	10	-	27760321	HT29	viability after 16 days	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.30553109241957754	[66,51]	[37,54,66]	-3	hSpCas9	negative selection	5167938
48404916	48404938	10	+	27760321	HT29	viability after 13 days	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.43618712331124293	[499,389]	[664,776,655]	5	hSpCas9	negative selection	5251397
48409887	48409909	10	-	27760321	HT29	viability after 13 days	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	0.9155276608015628	[15,12]	[17,71,6]	9	hSpCas9	negative selection	5251398
48410022	48410044	10	+	27760321	HT29	viability after 13 days	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-1.5873439377257208	[11,9]	[1,9,0]	-8	hSpCas9	negative selection	5251399
48410066	48410088	10	-	27760321	HT29	viability after 13 days	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.36076458084332075	[788,615]	[868,1124,1139]	4	hSpCas9	negative selection	5251400
48420254	48420276	10	-	27760321	HT29	viability after 13 days	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.029599168275181942	[66,51]	[72,82,47]	0	hSpCas9	negative selection	5251401
48404916	48404938	10	+	27760321	HT29	viability after 10 days	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	-0.06456034772594724	[499,389]	[623,394,569]	-1	hSpCas9	negative selection	5334860
48409887	48409909	10	-	27760321	HT29	viability after 10 days	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	0.029550399752241496	[15,12]	[0,54,0]	0	hSpCas9	negative selection	5334861
48410022	48410044	10	+	27760321	HT29	viability after 10 days	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-2.21786561589433	[11,9]	[0,5,1]	-9	hSpCas9	negative selection	5334862
48410066	48410088	10	-	27760321	HT29	viability after 10 days	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.4837489462888954	[788,615]	[1001,1377,1301]	6	hSpCas9	negative selection	5334863
48420254	48420276	10	-	27760321	HT29	viability after 10 days	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	0.1023274831405625	[66,51]	[42,52,140]	1	hSpCas9	negative selection	5334864
48404916	48404938	10	+	27760321	MOLM13	viability	AATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	1.199746429035088	[676,499]	[294,1147]	8	hSpCas9	negative selection	5418323
48409887	48409909	10	-	27760321	MOLM13	viability	TGGTGTGAAAACATTCAAAAGG	MAPK8	ENSG00000107643	-2.9064201345902614	[9,15]	[0,0]	-9	hSpCas9	negative selection	5418324
48410022	48410044	10	+	27760321	MOLM13	viability	TCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-2.8181215853515242	[12,11]	[0,0]	-8	hSpCas9	negative selection	5418325
48410066	48410088	10	-	27760321	MOLM13	viability	TAGCTCCATCTGAATCACTTGG	MAPK8	ENSG00000107643	0.8136226983089753	[913,788]	[551,1088]	5	hSpCas9	negative selection	5418326
48420254	48420276	10	-	27760321	MOLM13	viability	AGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.08449897190264588	[118,66]	[7,82]	0	hSpCas9	negative selection	5418327
48306702	48306725	10	+	27661255	K562	viability	GGACGACGCGGCTTGGATTGCGG	MAPK8	ENSG00000107643	0.08493435262389315	[1383,1630]	[1341,1214]	3	dCas9-KRAB	negative selection	5492239
48306733	48306756	10	+	27661255	K562	viability	GCAGCGCTGGGTAACGGCCGCGG	MAPK8	ENSG00000107643	0.36562906743633805	[356,478]	[448,409]	9	dCas9-KRAB	negative selection	5492240
48306962	48306985	10	+	27661255	K562	viability	GGGCGGCGCGGGAACAATAGCGG	MAPK8	ENSG00000107643	-0.01754231017755005	[759,660]	[668,470]	0	dCas9-KRAB	negative selection	5492241
48307095	48307118	10	-	27661255	K562	viability	GAGGCAGGACCCACGCGAAGAGG	MAPK8	ENSG00000107643	0.23114121979191876	[548,554]	[632,418]	7	dCas9-KRAB	negative selection	5492242
48420268	48420291	10	+	27260156	BXPC3	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.1887608699282698	[845]	[649,751,921,794]	-4	hSpCas9	negative selection	5554402
48420254	48420277	10	-	27260156	BXPC3	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.21499061421657784	[1143]	[906,978,1133,1124]	-5	hSpCas9	negative selection	5554403
48410060	48410083	10	+	27260156	BXPC3	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.4063539788826155	[207]	[217,272,300,378]	8	hSpCas9	negative selection	5554404
48404914	48404937	10	+	27260156	BXPC3	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.08754108183544507	[314]	[231,392,328,467]	2	hSpCas9	negative selection	5618660
48404907	48404930	10	-	27260156	BXPC3	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.2910396436164149	[136]	[195,110,212,182]	6	hSpCas9	negative selection	5618661
48410021	48410044	10	+	27260156	BXPC3	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.1825655389838945	[404]	[341,368,336,454]	-4	hSpCas9	negative selection	5618662
48420268	48420291	10	+	27260156	A673	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.22011299439528031	[845]	[873,794,904,916]	-5	hSpCas9	negative selection	5675653
48420254	48420277	10	-	27260156	A673	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.4585449544570882	[1143]	[943,1135,999,900]	-8	hSpCas9	negative selection	5675654
48410060	48410083	10	+	27260156	A673	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.29176591297126353	[207]	[310,278,289,345]	6	hSpCas9	negative selection	5675655
48404914	48404937	10	+	27260156	A673	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.012269374365337482	[314]	[499,313,386,336]	0	hSpCas9	negative selection	5739911
48404907	48404930	10	-	27260156	A673	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.1390252439538362	[136]	[284,170,131,146]	3	hSpCas9	negative selection	5739912
48410021	48410044	10	+	27260156	A673	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.18731745487711027	[404]	[577,310,412,425]	-5	hSpCas9	negative selection	5739913
48420268	48420291	10	+	27260156	A375	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.2701343691342257	[845]	[809,986,684,815]	-4	hSpCas9	negative selection	5796904
48420254	48420277	10	-	27260156	A375	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.2191440708956658	[1143]	[1212,1337,1238,858]	-3	hSpCas9	negative selection	5796905
48410060	48410083	10	+	27260156	A375	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.41861965976208293	[207]	[413,374,345,186]	6	hSpCas9	negative selection	5796906
48404914	48404937	10	+	27260156	A375	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.15590642917684888	[314]	[417,630,340,292]	2	hSpCas9	negative selection	5861162
48404907	48404930	10	-	27260156	A375	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.714860487816672	[136]	[55,76,114,133]	-7	hSpCas9	negative selection	5861163
48410021	48410044	10	+	27260156	A375	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.0009507224684324189	[404]	[264,818,538,329]	0	hSpCas9	negative selection	5861164
48420268	48420291	10	+	27260156	COLO741	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.005076401657060137	[845]	[1145,1154,943]	0	hSpCas9	negative selection	5918155
48420254	48420277	10	-	27260156	COLO741	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.533832597387519	[1143]	[1312,844,901]	-8	hSpCas9	negative selection	5918156
48410060	48410083	10	+	27260156	COLO741	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.39255371805527106	[207]	[323,387,332]	7	hSpCas9	negative selection	5918157
48404914	48404937	10	+	27260156	COLO741	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.2151695808496692	[314]	[592,336,479]	4	hSpCas9	negative selection	5982413
48404907	48404930	10	-	27260156	COLO741	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.15444801179599166	[136]	[223,230,135]	3	hSpCas9	negative selection	5982414
48410021	48410044	10	+	27260156	COLO741	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.012917179408250656	[404]	[528,684,363]	0	hSpCas9	negative selection	5982415
48420268	48420291	10	+	27260156	CAL120	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.42409256458377725	[845]	[1072,598,725]	-6	hSpCas9	negative selection	6039406
48420254	48420277	10	-	27260156	CAL120	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.5297937832452942	[1143]	[613,979,1301]	-6	hSpCas9	negative selection	6039407
48410060	48410083	10	+	27260156	CAL120	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.09851796472313401	[207]	[420,159,271]	1	hSpCas9	negative selection	6039408
48404914	48404937	10	+	27260156	CAL120	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.2675271322622629	[314]	[469,342,187]	-4	hSpCas9	negative selection	6103664
48404907	48404930	10	-	27260156	CAL120	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.04540774916710255	[136]	[170,236,119]	0	hSpCas9	negative selection	6103665
48410021	48410044	10	+	27260156	CAL120	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.6668107512157473	[404]	[401,415,149]	-7	hSpCas9	negative selection	6103666
48420268	48420291	10	+	27260156	CADOES1	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.3135297642419004	[845]	[771,560,643,551]	-5	hSpCas9	negative selection	6160657
48420254	48420277	10	-	27260156	CADOES1	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.5311988123593314	[1143]	[665,771,726,781]	-7	hSpCas9	negative selection	6160658
48410060	48410083	10	+	27260156	CADOES1	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	-0.017451731919611913	[207]	[215,144,118,287]	0	hSpCas9	negative selection	6160659
48404914	48404937	10	+	27260156	CADOES1	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.08391567452673393	[314]	[227,348,286,380]	1	hSpCas9	negative selection	6224915
48404907	48404930	10	-	27260156	CADOES1	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.2492733537147711	[136]	[122,216,114,150]	4	hSpCas9	negative selection	6224916
48410021	48410044	10	+	27260156	CADOES1	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.17412983864448528	[404]	[522,297,252,257]	-3	hSpCas9	negative selection	6224917
48420268	48420291	10	+	27260156	EWS502	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.30492541652027194	[845]	[466,611,850,1027]	-5	hSpCas9	negative selection	6281908
48420254	48420277	10	-	27260156	EWS502	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.45711455410989665	[1143]	[826,941,774,993]	-7	hSpCas9	negative selection	6281909
48410060	48410083	10	+	27260156	EWS502	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.6013614953959499	[207]	[217,307,348,486]	9	hSpCas9	negative selection	6281910
48404914	48404937	10	+	27260156	EWS502	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.0669632670427156	[314]	[345,177,414,338]	-1	hSpCas9	negative selection	6346166
48404907	48404930	10	-	27260156	EWS502	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.2265932887156168	[136]	[166,78,185,256]	4	hSpCas9	negative selection	6346167
48410021	48410044	10	+	27260156	EWS502	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.12399094583625851	[404]	[552,334,453,524]	2	hSpCas9	negative selection	6346168
48420268	48420291	10	+	27260156	EW8	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.33325981859250176	[845]	[507,589,486,595]	-6	hSpCas9	negative selection	6403159
48420254	48420277	10	-	27260156	EW8	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.26853681787082384	[1143]	[782,1094,567,667]	-5	hSpCas9	negative selection	6403160
48410060	48410083	10	+	27260156	EW8	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.5356299075038186	[207]	[301,254,197,235]	8	hSpCas9	negative selection	6403161
48404914	48404937	10	+	27260156	EW8	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.16783483102626595	[314]	[227,169,226,282]	-3	hSpCas9	negative selection	6467417
48404907	48404930	10	-	27260156	EW8	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.08186751326295028	[136]	[125,147,98,49]	-1	hSpCas9	negative selection	6467418
48410021	48410044	10	+	27260156	EW8	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.14061883678717035	[404]	[226,334,401,200]	-3	hSpCas9	negative selection	6467419
48420268	48420291	10	+	27260156	CORL105	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.3682337970095252	[845]	[897,525,881,789]	-6	hSpCas9	negative selection	6524410
48420254	48420277	10	-	27260156	CORL105	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.42670367024774136	[1143]	[832,1055,1215,907]	-7	hSpCas9	negative selection	6524411
48410060	48410083	10	+	27260156	CORL105	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	-0.0966141061020711	[207]	[185,97,369,279]	-2	hSpCas9	negative selection	6524412
48404914	48404937	10	+	27260156	CORL105	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.03690957155629315	[314]	[309,313,568,276]	0	hSpCas9	negative selection	6588668
48404907	48404930	10	-	27260156	CORL105	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.16428914690956264	[136]	[126,121,110,206]	-3	hSpCas9	negative selection	6588669
48410021	48410044	10	+	27260156	CORL105	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.3531382088612714	[404]	[371,360,384,368]	-6	hSpCas9	negative selection	6588670
48420268	48420291	10	+	27260156	HS294T	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.031680037660894	[845]	[362,321,227,369]	0	hSpCas9	negative selection	6645661
48420254	48420277	10	-	27260156	HS294T	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	0.3565643987869844	[1143]	[246,1075,542,379]	5	hSpCas9	negative selection	6645662
48410060	48410083	10	+	27260156	HS294T	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.36608510448113873	[207]	[170,81,68,82]	5	hSpCas9	negative selection	6645663
48404914	48404937	10	+	27260156	HS294T	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.2684374195775312	[314]	[95,108,89,110]	-4	hSpCas9	negative selection	6709919
48404907	48404930	10	-	27260156	HS294T	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.7632336119840979	[136]	[26,43,20,32]	-8	hSpCas9	negative selection	6709920
48410021	48410044	10	+	27260156	HS294T	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.23308235041592398	[404]	[160,236,128,213]	3	hSpCas9	negative selection	6709921
48420268	48420291	10	+	27260156	HCC44	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.25539268223757305	[845]	[763,724,1044,717]	-4	hSpCas9	negative selection	6766912
48420254	48420277	10	-	27260156	HCC44	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.4569026704036667	[1143]	[961,609,1220,1062]	-6	hSpCas9	negative selection	6766913
48410060	48410083	10	+	27260156	HCC44	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.23169076111301345	[207]	[257,151,257,441]	4	hSpCas9	negative selection	6766914
48404914	48404937	10	+	27260156	HCC44	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.16989431629839968	[314]	[263,221,487,327]	-3	hSpCas9	negative selection	6831170
48404907	48404930	10	-	27260156	HCC44	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.11730674968858579	[136]	[110,149,244,79]	-2	hSpCas9	negative selection	6831171
48410021	48410044	10	+	27260156	HCC44	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.05895428944887654	[404]	[451,422,574,476]	0	hSpCas9	negative selection	6831172
48420268	48420291	10	+	27260156	G402	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.690871270178843	[845]	[1240,1194,2674,1468]	8	hSpCas9	negative selection	6888163
48420254	48420277	10	-	27260156	G402	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	0.3394365272929538	[1143]	[2403,1921,1446,1403]	4	hSpCas9	negative selection	6888164
48410060	48410083	10	+	27260156	G402	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.45261645333469536	[207]	[590,299,257,274]	5	hSpCas9	negative selection	6888165
48404914	48404937	10	+	27260156	G402	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.7545534631473974	[314]	[483,644,463,958]	8	hSpCas9	negative selection	6952421
48404907	48404930	10	-	27260156	G402	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	1.0348551511616533	[136]	[783,343,246,70]	9	hSpCas9	negative selection	6952422
48410021	48410044	10	+	27260156	G402	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.5169306755243867	[404]	[510,998,397,896]	6	hSpCas9	negative selection	6952423
48420268	48420291	10	+	27260156	L33	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.05794854678378025	[845]	[834,349,474,804]	-1	hSpCas9	negative selection	7009414
48420254	48420277	10	-	27260156	L33	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.3129070655099412	[1143]	[1013,345,613,846]	-6	hSpCas9	negative selection	7009415
48410060	48410083	10	+	27260156	L33	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.25738363184110924	[207]	[265,106,162,207]	5	hSpCas9	negative selection	7009416
48404914	48404937	10	+	27260156	L33	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.17599655661229274	[314]	[224,138,181,262]	-4	hSpCas9	negative selection	7073672
48404907	48404930	10	-	27260156	L33	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.079429457083664	[136]	[104,24,134,198]	1	hSpCas9	negative selection	7073673
48410021	48410044	10	+	27260156	L33	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.05239548356339929	[404]	[335,118,256,526]	-1	hSpCas9	negative selection	7073674
48420268	48420291	10	+	27260156	K562	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.7459349112822227	[845]	[509,487,293,497]	-7	hSpCas9	negative selection	7130665
48420254	48420277	10	-	27260156	K562	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-1.3409757082128586	[1143]	[341,498,428,338]	-8	hSpCas9	negative selection	7130666
48410060	48410083	10	+	27260156	K562	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	-0.30188853252699155	[207]	[105,87,214,178]	-4	hSpCas9	negative selection	7130667
48404914	48404937	10	+	27260156	K562	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.041806098755626686	[314]	[481,364,99,171]	0	hSpCas9	negative selection	7194923
48404907	48404930	10	-	27260156	K562	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.48519572865531413	[136]	[73,84,100,85]	-5	hSpCas9	negative selection	7194924
48410021	48410044	10	+	27260156	K562	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.5906874361367924	[404]	[190,264,132,348]	-6	hSpCas9	negative selection	7194925
48420268	48420291	10	+	27260156	HT29	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.14251849626515944	[845]	[1352,926,1175,1081]	2	hSpCas9	negative selection	7251916
48420254	48420277	10	-	27260156	HT29	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.02188712768654688	[1143]	[1595,1441,1277,1197]	0	hSpCas9	negative selection	7251917
48410060	48410083	10	+	27260156	HT29	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.7865613279173099	[207]	[420,349,508,450]	9	hSpCas9	negative selection	7251918
48404914	48404937	10	+	27260156	HT29	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.1140719011118897	[314]	[299,298,371,423]	-2	hSpCas9	negative selection	7316174
48404907	48404930	10	-	27260156	HT29	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.011034357486348512	[136]	[202,160,111,192]	0	hSpCas9	negative selection	7316175
48410021	48410044	10	+	27260156	HT29	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.00013772699501449215	[404]	[605,527,437,414]	0	hSpCas9	negative selection	7316176
48420268	48420291	10	+	27260156	MHHES1	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.11789890920992396	[845]	[842,1080,1125,1041]	2	hSpCas9	negative selection	7373167
48420254	48420277	10	-	27260156	MHHES1	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.14681782414651323	[1143]	[1316,1245,1223,924]	-3	hSpCas9	negative selection	7373168
48410060	48410083	10	+	27260156	MHHES1	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.4237673583708039	[207]	[351,331,319,263]	7	hSpCas9	negative selection	7373169
48404914	48404937	10	+	27260156	MHHES1	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.14175064803636783	[314]	[468,319,410,364]	2	hSpCas9	negative selection	7437425
48404907	48404930	10	-	27260156	MHHES1	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.703911352674943	[136]	[125,97,63,92]	-8	hSpCas9	negative selection	7437426
48410021	48410044	10	+	27260156	MHHES1	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.20891432705568902	[404]	[469,471,571,561]	4	hSpCas9	negative selection	7437427
48420268	48420291	10	+	27260156	MEWO	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.20229948639255535	[845]	[735,677,658]	-4	hSpCas9	negative selection	7494418
48420254	48420277	10	-	27260156	MEWO	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.39823682194122545	[1143]	[913,791,749]	-7	hSpCas9	negative selection	7494419
48410060	48410083	10	+	27260156	MEWO	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.5371461891626438	[207]	[347,238,272]	9	hSpCas9	negative selection	7494420
48404914	48404937	10	+	27260156	MEWO	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.2327142501777426	[314]	[274,257,223]	-5	hSpCas9	negative selection	7558676
48404907	48404930	10	-	27260156	MEWO	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.3594307807567254	[136]	[115,61,124]	-7	hSpCas9	negative selection	7558677
48410021	48410044	10	+	27260156	MEWO	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.1186585423780504	[404]	[337,297,408]	-3	hSpCas9	negative selection	7558678
48420268	48420291	10	+	27260156	LNCAPCLONEFGC	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.47392873550894304	[845]	[607,391,664,567]	-6	hSpCas9	negative selection	7615669
48420254	48420277	10	-	27260156	LNCAPCLONEFGC	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.49440517194307043	[1143]	[595,769,907,693]	-6	hSpCas9	negative selection	7615670
48410060	48410083	10	+	27260156	LNCAPCLONEFGC	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.1702926587487099	[207]	[179,289,188,180]	2	hSpCas9	negative selection	7615671
48404914	48404937	10	+	27260156	LNCAPCLONEFGC	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.04143724300207208	[314]	[264,306,309,229]	0	hSpCas9	negative selection	7679927
48404907	48404930	10	-	27260156	LNCAPCLONEFGC	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.2702353334951402	[136]	[82,124,92,107]	-4	hSpCas9	negative selection	7679928
48410021	48410044	10	+	27260156	LNCAPCLONEFGC	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.005510593096140826	[404]	[459,315,202,470]	0	hSpCas9	negative selection	7679929
48420268	48420291	10	+	27260156	PANC0327	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.31918254990000683	[845]	[1067,535,513,337]	-5	hSpCas9	negative selection	7736920
48420254	48420277	10	-	27260156	PANC0327	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.5251842642255061	[1143]	[981,559,744,578]	-6	hSpCas9	negative selection	7736921
48410060	48410083	10	+	27260156	PANC0327	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	-0.36906590542043993	[207]	[152,103,124,195]	-5	hSpCas9	negative selection	7736922
48404914	48404937	10	+	27260156	PANC0327	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.4408806236916487	[314]	[279,466,471,280]	6	hSpCas9	negative selection	7801178
48404907	48404930	10	-	27260156	PANC0327	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.013067804741355493	[136]	[124,202,54,88]	0	hSpCas9	negative selection	7801179
48410021	48410044	10	+	27260156	PANC0327	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.46033230202153413	[404]	[198,517,330,903]	6	hSpCas9	negative selection	7801180
48420268	48420291	10	+	27260156	NCIH2009	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.5027495704289031	[845]	[966,968,588]	-6	hSpCas9	negative selection	7858171
48420254	48420277	10	-	27260156	NCIH2009	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.5487092329641035	[1143]	[1466,936,948]	-6	hSpCas9	negative selection	7858172
48410060	48410083	10	+	27260156	NCIH2009	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	-0.2922509528561117	[207]	[308,221,194]	-4	hSpCas9	negative selection	7858173
48404914	48404937	10	+	27260156	NCIH2009	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.04481904667238046	[314]	[586,370,430]	0	hSpCas9	negative selection	7922429
48404907	48404930	10	-	27260156	NCIH2009	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.08315350054733828	[136]	[350,93,131]	-1	hSpCas9	negative selection	7922430
48410021	48410044	10	+	27260156	NCIH2009	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.05110680916446245	[404]	[588,547,621]	0	hSpCas9	negative selection	7922431
48420268	48420291	10	+	27260156	NCIH1373	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.2782489511518502	[845]	[799,971,676,170]	-3	hSpCas9	negative selection	7979422
48420254	48420277	10	-	27260156	NCIH1373	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.7657611242323753	[1143]	[1282,660,498,173]	-6	hSpCas9	negative selection	7979423
48410060	48410083	10	+	27260156	NCIH1373	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	-0.5950354908229025	[207]	[242,131,95,42]	-5	hSpCas9	negative selection	7979424
48404914	48404937	10	+	27260156	NCIH1373	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.020776591365553876	[314]	[655,170,117,149]	0	hSpCas9	negative selection	8043680
48404907	48404930	10	-	27260156	NCIH1373	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-1.090512035777255	[136]	[122,26,46,27]	-8	hSpCas9	negative selection	8043681
48410021	48410044	10	+	27260156	NCIH1373	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.9834587071639438	[404]	[285,136,335,44]	-7	hSpCas9	negative selection	8043682
48420268	48420291	10	+	27260156	PATU8902	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.021044045704974867	[845]	[1700,835,1133,1097]	0	hSpCas9	negative selection	8100673
48420254	48420277	10	-	27260156	PATU8902	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.13657906397928277	[1143]	[1160,1837,1560,1167]	-1	hSpCas9	negative selection	8100674
48410060	48410083	10	+	27260156	PATU8902	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	-0.12011721332445302	[207]	[361,243,192,284]	-1	hSpCas9	negative selection	8100675
48404914	48404937	10	+	27260156	PATU8902	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.20015301192792867	[314]	[506,711,309,537]	2	hSpCas9	negative selection	8164931
48404907	48404930	10	-	27260156	PATU8902	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.752146270510176	[136]	[98,389,216,645]	7	hSpCas9	negative selection	8164932
48410021	48410044	10	+	27260156	PATU8902	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.5229415108713602	[404]	[787,631,996,763]	5	hSpCas9	negative selection	8164933
48420268	48420291	10	+	27260156	PANC1	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.4190836469385078	[845]	[614,483,682,394]	-6	hSpCas9	negative selection	8221924
48420254	48420277	10	-	27260156	PANC1	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.7388769995327971	[1143]	[641,614,643,468]	-8	hSpCas9	negative selection	8221925
48410060	48410083	10	+	27260156	PANC1	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	-0.12081284164913564	[207]	[131,209,154,166]	-2	hSpCas9	negative selection	8221926
48404914	48404937	10	+	27260156	PANC1	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.14582901726138803	[314]	[380,414,290,151]	2	hSpCas9	negative selection	8286182
48404907	48404930	10	-	27260156	PANC1	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.0361360075088657	[136]	[186,41,93,116]	0	hSpCas9	negative selection	8286183
48410021	48410044	10	+	27260156	PANC1	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.06836230260101842	[404]	[289,575,351,291]	1	hSpCas9	negative selection	8286184
48420268	48420291	10	+	27260156	PANC0813	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.05076539447081285	[845]	[862,1116,1082,774]	-1	hSpCas9	negative selection	8343175
48420254	48420277	10	-	27260156	PANC0813	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.17206756848116878	[1143]	[1465,1318,1016,1001]	-3	hSpCas9	negative selection	8343176
48410060	48410083	10	+	27260156	PANC0813	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.06352960559353504	[207]	[230,389,158,238]	1	hSpCas9	negative selection	8343177
48404914	48404937	10	+	27260156	PANC0813	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.024289831737606238	[314]	[380,298,390,430]	0	hSpCas9	negative selection	8407433
48404907	48404930	10	-	27260156	PANC0813	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.14837232615039975	[136]	[135,79,302,65]	-2	hSpCas9	negative selection	8407434
48410021	48410044	10	+	27260156	PANC0813	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.30630550285511354	[404]	[688,649,371,645]	5	hSpCas9	negative selection	8407435
48420268	48420291	10	+	27260156	RDES	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.06267109983790031	[845]	[1062,685,823,1142]	-1	hSpCas9	negative selection	8464426
48420254	48420277	10	-	27260156	RDES	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.5508810157912304	[1143]	[772,818,955,1080]	-7	hSpCas9	negative selection	8464427
48410060	48410083	10	+	27260156	RDES	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.1906037961921967	[207]	[202,326,255,312]	3	hSpCas9	negative selection	8464428
48404914	48404937	10	+	27260156	RDES	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.23631347290264898	[314]	[403,362,551,382]	4	hSpCas9	negative selection	8528684
48404907	48404930	10	-	27260156	RDES	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.3554103669648405	[136]	[109,136,125,115]	-6	hSpCas9	negative selection	8528685
48410021	48410044	10	+	27260156	RDES	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.03851305534370694	[404]	[383,409,617,526]	0	hSpCas9	negative selection	8528686
48420268	48420291	10	+	27260156	PC3	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.5405599521337727	[845]	[390,465,815,775]	-8	hSpCas9	negative selection	8585677
48420254	48420277	10	-	27260156	PC3	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.660989318178315	[1143]	[469,670,1312,700]	-9	hSpCas9	negative selection	8585678
48410060	48410083	10	+	27260156	PC3	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.1824172386362377	[207]	[195,190,277,284]	4	hSpCas9	negative selection	8585679
48404914	48404937	10	+	27260156	PC3	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.20483285881487995	[314]	[175,497,601,306]	4	hSpCas9	negative selection	8649935
48404907	48404930	10	-	27260156	PC3	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.18260444139120824	[136]	[79,86,234,131]	-4	hSpCas9	negative selection	8649936
48410021	48410044	10	+	27260156	PC3	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.048527048987978355	[404]	[264,372,798,409]	1	hSpCas9	negative selection	8649937
48420268	48420291	10	+	27260156	PATU8988T	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.059974702114817036	[845]	[706,758,842,827]	-1	hSpCas9	negative selection	8706928
48420254	48420277	10	-	27260156	PATU8988T	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.40052809238191145	[1143]	[785,1029,592,972]	-6	hSpCas9	negative selection	8706929
48410060	48410083	10	+	27260156	PATU8988T	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.49805384567181665	[207]	[438,229,225,231]	8	hSpCas9	negative selection	8706930
48404914	48404937	10	+	27260156	PATU8988T	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.1306064092864786	[314]	[359,310,334,323]	2	hSpCas9	negative selection	8771186
48404907	48404930	10	-	27260156	PATU8988T	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.24034688065291587	[136]	[182,260,84,102]	4	hSpCas9	negative selection	8771187
48410021	48410044	10	+	27260156	PATU8988T	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.1899403224527405	[404]	[306,284,230,562]	-3	hSpCas9	negative selection	8771188
48420268	48420291	10	+	27260156	T47D	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.31053699238455856	[845]	[738,825,800,809]	-6	hSpCas9	negative selection	8828179
48420254	48420277	10	-	27260156	T47D	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.5049414920865088	[1143]	[904,851,1000,1006]	-8	hSpCas9	negative selection	8828180
48410060	48410083	10	+	27260156	T47D	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.07287513656445088	[207]	[285,215,280,238]	1	hSpCas9	negative selection	8828181
48404914	48404937	10	+	27260156	T47D	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.19008526399137626	[314]	[305,381,292,299]	-4	hSpCas9	negative selection	8892437
48404907	48404930	10	-	27260156	T47D	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.05927102443257248	[136]	[158,130,177,145]	-1	hSpCas9	negative selection	8892438
48410021	48410044	10	+	27260156	T47D	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.10701891227153593	[404]	[491,348,490,426]	-2	hSpCas9	negative selection	8892439
48420268	48420291	10	+	27260156	SU8686	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.44381876930587627	[845]	[664,625,533,629]	-6	hSpCas9	negative selection	8949430
48420254	48420277	10	-	27260156	SU8686	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.13861555359750755	[1143]	[984,829,1048,1329]	-2	hSpCas9	negative selection	8949431
48410060	48410083	10	+	27260156	SU8686	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	-0.024865725178190967	[207]	[236,106,165,326]	0	hSpCas9	negative selection	8949432
48404914	48404937	10	+	27260156	SU8686	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.07782629633075766	[314]	[292,214,346,346]	-1	hSpCas9	negative selection	9013688
48404907	48404930	10	-	27260156	SU8686	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.1186829716710196	[136]	[192,128,140,117]	2	hSpCas9	negative selection	9013689
48410021	48410044	10	+	27260156	SU8686	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.01637985794937183	[404]	[358,290,397,629]	0	hSpCas9	negative selection	9013690
48420268	48420291	10	+	27260156	SKES1	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.27932249495994377	[845]	[755,670,750,610]	-6	hSpCas9	negative selection	9070681
48420254	48420277	10	-	27260156	SKES1	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.24300618199746293	[1143]	[1031,1110,784,949]	-5	hSpCas9	negative selection	9070682
48410060	48410083	10	+	27260156	SKES1	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	-0.0566811873856099	[207]	[210,273,159,165]	-1	hSpCas9	negative selection	9070683
48404914	48404937	10	+	27260156	SKES1	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.07935171424766574	[314]	[289,383,349,303]	1	hSpCas9	negative selection	9134939
48404907	48404930	10	-	27260156	SKES1	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.6643011333027358	[136]	[145,96,51,61]	-9	hSpCas9	negative selection	9134940
48410021	48410044	10	+	27260156	SKES1	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.05748870937830672	[404]	[371,539,417,361]	1	hSpCas9	negative selection	9134941
48420268	48420291	10	+	27260156	TOV112D	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.38699041533110623	[845]	[799,589,612,587]	-6	hSpCas9	negative selection	9191932
48420254	48420277	10	-	27260156	TOV112D	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.4955660798011565	[1143]	[758,1001,846,686]	-7	hSpCas9	negative selection	9191933
48410060	48410083	10	+	27260156	TOV112D	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	-0.005007819162859306	[207]	[303,177,108,238]	0	hSpCas9	negative selection	9191934
48404914	48404937	10	+	27260156	TOV112D	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.18447262519536145	[314]	[285,264,183,369]	-4	hSpCas9	negative selection	9256190
48404907	48404930	10	-	27260156	TOV112D	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.7067285819815623	[136]	[83,91,110,51]	-8	hSpCas9	negative selection	9256191
48410021	48410044	10	+	27260156	TOV112D	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.19212872937190978	[404]	[805,233,529,260]	3	hSpCas9	negative selection	9256192
48420268	48420291	10	+	27260156	TC71	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.20892246998089958	[845]	[793,731,783,830]	-5	hSpCas9	negative selection	9313183
48420254	48420277	10	-	27260156	TC71	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.4736626913465164	[1143]	[763,952,866,955]	-8	hSpCas9	negative selection	9313184
48410060	48410083	10	+	27260156	TC71	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.6759850210531579	[207]	[391,460,224,349]	9	hSpCas9	negative selection	9313185
48404914	48404937	10	+	27260156	TC71	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.07073224976414161	[314]	[383,307,313,416]	1	hSpCas9	negative selection	9377441
48404907	48404930	10	-	27260156	TC71	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	0.1281816465919241	[136]	[153,179,63,252]	3	hSpCas9	negative selection	9377442
48410021	48410044	10	+	27260156	TC71	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	-0.2083841516513656	[404]	[441,339,289,435]	-5	hSpCas9	negative selection	9377443
48420268	48420291	10	+	27260156	TC32	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.4237901106046817	[845]	[594,411,743,683]	-7	hSpCas9	negative selection	9434434
48420254	48420277	10	-	27260156	TC32	viability	TAGTAGCGAGTCACTACATAAGG	MAPK8	ENSG00000107643	-0.25331607848922677	[1143]	[689,853,1139,956]	-4	hSpCas9	negative selection	9434435
48410060	48410083	10	+	27260156	TC32	viability	TCTTTGCCAAGTGATTCAGATGG	MAPK8	ENSG00000107643	0.30189314141384394	[207]	[287,171,308,209]	5	hSpCas9	negative selection	9434436
48404914	48404937	10	+	27260156	TC32	viability	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.053890546945902784	[314]	[230,181,348,427]	-1	hSpCas9	negative selection	9498692
48404907	48404930	10	-	27260156	TC32	viability	GCATGAGTCTGATTCTGAAATGG	MAPK8	ENSG00000107643	-0.05390373018050165	[136]	[124,139,121,91]	-1	hSpCas9	negative selection	9498693
48410021	48410044	10	+	27260156	TC32	viability	CTCATAAAGTTACATAGTCATGG	MAPK8	ENSG00000107643	0.059431072958268244	[404]	[305,337,606,380]	1	hSpCas9	negative selection	9498694
48404914	48404937	10	+	27869803	HPAFII	viability after 27 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.9650455238724924	[348]	[361,354,NaN]	7	hSpCas9	negative selection	9537999
48404915	48404938	10	+	27869803	HPAFII	viability after 27 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	-0.13633622324756858	[278]	[247,37,NaN]	-1	hSpCas9	negative selection	9538000
48420268	48420291	10	+	27869803	HPAFII	viability after 27 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.07305945068642417	[813]	[441,456,NaN]	0	hSpCas9	negative selection	9538001
48420283	48420306	10	+	27869803	HPAFII	viability after 27 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.3731398984314432	[303]	[278,146,NaN]	3	hSpCas9	negative selection	9538002
48427117	48427140	10	+	27869803	HPAFII	viability after 27 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.07480640755888124	[197]	[65,145,NaN]	0	hSpCas9	negative selection	9538003
48431232	48431255	10	+	27869803	HPAFII	viability after 27 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.3473834638722568	[668]	[498,90,NaN]	-3	hSpCas9	negative selection	9538004
48404914	48404937	10	+	27869803	HPAFII	viability after 15 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.5842484222066155	[348]	[660,500,NaN]	6	hSpCas9	negative selection	9620448
48404915	48404938	10	+	27869803	HPAFII	viability after 15 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	-0.19081544310089107	[278]	[451,144,NaN]	-2	hSpCas9	negative selection	9620449
48420268	48420291	10	+	27869803	HPAFII	viability after 15 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.33018314173749297	[813]	[915,558,NaN]	-4	hSpCas9	negative selection	9620450
48420283	48420306	10	+	27869803	HPAFII	viability after 15 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.5676985458820847	[303]	[630,392,NaN]	6	hSpCas9	negative selection	9620451
48427117	48427140	10	+	27869803	HPAFII	viability after 15 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.3843682044513597	[197]	[265,98,NaN]	-4	hSpCas9	negative selection	9620452
48431232	48431255	10	+	27869803	HPAFII	viability after 15 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.05474441965035104	[668]	[928,544,NaN]	0	hSpCas9	negative selection	9620453
48404914	48404937	10	+	27869803	ASPC1	viability after 36 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.833814137158165	[1038]	[1265,357,433]	7	hSpCas9	negative selection	9702897
48404915	48404938	10	+	27869803	ASPC1	viability after 36 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.10733321923918128	[584]	[210,64,346]	1	hSpCas9	negative selection	9702898
48420268	48420291	10	+	27869803	ASPC1	viability after 36 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.3693684741263574	[1508]	[980,515,592]	3	hSpCas9	negative selection	9702899
48420283	48420306	10	+	27869803	ASPC1	viability after 36 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	1.4007642888423375	[762]	[934,525,673]	9	hSpCas9	negative selection	9702900
48427117	48427140	10	+	27869803	ASPC1	viability after 36 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-1.2519435772207217	[538]	[72,81,79]	-8	hSpCas9	negative selection	9702901
48431232	48431255	10	+	27869803	ASPC1	viability after 36 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	0.6266093145315306	[1878]	[832,1202,976]	6	hSpCas9	negative selection	9702902
48404914	48404937	10	+	27869803	PATU8988S	viability after 35 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	-0.3196314959334313	[805]	[306,212,NaN]	-3	hSpCas9	negative selection	9785346
48404915	48404938	10	+	27869803	PATU8988S	viability after 35 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	-0.11643464042216631	[466]	[173,172,NaN]	-1	hSpCas9	negative selection	9785347
48420268	48420291	10	+	27869803	PATU8988S	viability after 35 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.939831464379931	[1162]	[911,884,NaN]	8	hSpCas9	negative selection	9785348
48420283	48420306	10	+	27869803	PATU8988S	viability after 35 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.15254838198742898	[669]	[272,326,NaN]	1	hSpCas9	negative selection	9785349
48427117	48427140	10	+	27869803	PATU8988S	viability after 35 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.512099791770291	[334]	[154,229,NaN]	6	hSpCas9	negative selection	9785350
48431232	48431255	10	+	27869803	PATU8988S	viability after 35 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.5312996924476041	[1677]	[518,415,NaN]	-5	hSpCas9	negative selection	9785351
48404914	48404937	10	+	27869803	PATU8988S	viability after 31 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.19834149156624048	[805]	[333,412,NaN]	2	hSpCas9	negative selection	9867795
48404915	48404938	10	+	27869803	PATU8988S	viability after 31 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.1289814306986931	[466]	[145,276,NaN]	1	hSpCas9	negative selection	9867796
48420268	48420291	10	+	27869803	PATU8988S	viability after 31 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.5733649595279506	[1162]	[682,698,NaN]	6	hSpCas9	negative selection	9867797
48420283	48420306	10	+	27869803	PATU8988S	viability after 31 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.30765403526776597	[669]	[232,454,NaN]	4	hSpCas9	negative selection	9867798
48427117	48427140	10	+	27869803	PATU8988S	viability after 31 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.4128962506794589	[334]	[183,169,NaN]	5	hSpCas9	negative selection	9867799
48431232	48431255	10	+	27869803	PATU8988S	viability after 31 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	-0.3190919978953355	[1677]	[567,495,NaN]	-4	hSpCas9	negative selection	9867800
48404914	48404937	10	+	27869803	HPAFII	viability after 35 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.8790731225921757	[348]	[339,307,NaN]	6	hSpCas9	negative selection	9950244
48404915	48404938	10	+	27869803	HPAFII	viability after 35 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.5182098150009915	[278]	[301,89,NaN]	3	hSpCas9	negative selection	9950245
48420268	48420291	10	+	27869803	HPAFII	viability after 35 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.15061336265923986	[813]	[376,547,NaN]	0	hSpCas9	negative selection	9950246
48420283	48420306	10	+	27869803	HPAFII	viability after 35 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.9649362103289545	[303]	[409,176,NaN]	6	hSpCas9	negative selection	9950247
48427117	48427140	10	+	27869803	HPAFII	viability after 35 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.4494977594909448	[197]	[55,92,NaN]	-3	hSpCas9	negative selection	9950248
48431232	48431255	10	+	27869803	HPAFII	viability after 35 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	0.2580887269418928	[668]	[690,82,NaN]	1	hSpCas9	negative selection	9950249
48404914	48404937	10	+	27869803	HPAFII	viability after 31 days	AGAATCAGACTCATGCCAAGCGG	MAPK8	ENSG00000107643	0.9653614209129553	[348]	[380,383,NaN]	7	hSpCas9	negative selection	10032693
48404915	48404938	10	+	27869803	HPAFII	viability after 31 days	GAATCAGACTCATGCCAAGCGGG	MAPK8	ENSG00000107643	0.44231364568522924	[278]	[318,96,NaN]	3	hSpCas9	negative selection	10032694
48420268	48420291	10	+	27869803	HPAFII	viability after 31 days	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.00999866827636664	[813]	[448,471,NaN]	0	hSpCas9	negative selection	10032695
48420283	48420306	10	+	27869803	HPAFII	viability after 31 days	ACCCGAGGTCATCCTTGGCATGG	MAPK8	ENSG00000107643	0.7662408618646095	[303]	[416,151,NaN]	5	hSpCas9	negative selection	10032696
48427117	48427140	10	+	27869803	HPAFII	viability after 31 days	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.30699765776906657	[197]	[96,81,NaN]	-2	hSpCas9	negative selection	10032697
48431232	48431255	10	+	27869803	HPAFII	viability after 31 days	CCAAGAATGGAGTTATACGGGGG	MAPK8	ENSG00000107643	0.09632858578072057	[668]	[621,160,NaN]	0	hSpCas9	negative selection	10032698
48427117	48427140	10	+	28162770	P31FUJ	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.30422581924307535	[50]	[73]	3	hSpCas9	negative selection	10189122
48425948	48425971	10	+	28162770	P31FUJ	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	0.8416969181992118	[216]	[456]	8	hSpCas9	negative selection	10189123
48431259	48431282	10	-	28162770	P31FUJ	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	0.19487950411668786	[141]	[190]	2	hSpCas9	negative selection	10189124
48420199	48420222	10	+	28162770	P31FUJ	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	-0.36900658801269004	[110]	[100]	-3	hSpCas9	negative selection	10189125
48420268	48420291	10	+	28162770	P31FUJ	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.22453458843077806	[173]	[174]	-2	hSpCas9	negative selection	10189126
48420295	48420318	10	-	28162770	P31FUJ	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	0.7358822551194133	[162]	[318]	8	hSpCas9	negative selection	10189127
48431203	48431226	10	+	28162770	P31FUJ	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.5761108720671662	[660]	[1157]	6	hSpCas9	negative selection	10189128
48431231	48431254	10	+	28162770	P31FUJ	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.11671925971683783	[579]	[738]	1	hSpCas9	negative selection	10189129
48420278	48420301	10	+	28162770	P31FUJ	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.33163797243343246	[235]	[348]	3	hSpCas9	negative selection	10189130
48420285	48420308	10	-	28162770	P31FUJ	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.47498019411489123	[798]	[1304]	5	hSpCas9	negative selection	10189131
48427117	48427140	10	+	28162770	TF1	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	NaN	[NaN]	[68]	1	hSpCas9	negative selection	10358488
48425948	48425971	10	+	28162770	TF1	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10358489
48431259	48431282	10	-	28162770	TF1	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10358490
48420199	48420222	10	+	28162770	TF1	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	NaN	[NaN]	[130]	1	hSpCas9	negative selection	10358491
48420268	48420291	10	+	28162770	TF1	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10358492
48420295	48420318	10	-	28162770	TF1	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	NaN	[NaN]	[273]	1	hSpCas9	negative selection	10358493
48431203	48431226	10	+	28162770	TF1	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	NaN	[NaN]	[723]	1	hSpCas9	negative selection	10358494
48431231	48431254	10	+	28162770	TF1	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	NaN	[NaN]	[642]	1	hSpCas9	negative selection	10358495
48420278	48420301	10	+	28162770	TF1	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	NaN	[NaN]	[227]	1	hSpCas9	negative selection	10358496
48420285	48420308	10	-	28162770	TF1	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	NaN	[NaN]	[618]	1	hSpCas9	negative selection	10358497
48427117	48427140	10	+	28162770	SKM1	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.3656253051537657	[17]	[40]	3	hSpCas9	negative selection	10527854
48425948	48425971	10	+	28162770	SKM1	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	0.7439776993315779	[50]	[150]	7	hSpCas9	negative selection	10527855
48431259	48431282	10	-	28162770	SKM1	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	0.35857054761981527	[44]	[101]	3	hSpCas9	negative selection	10527856
48420199	48420222	10	+	28162770	SKM1	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	0.1779983019779947	[31]	[63]	1	hSpCas9	negative selection	10527857
48420268	48420291	10	+	28162770	SKM1	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	1.0080733005356821	[35]	[127]	8	hSpCas9	negative selection	10527858
48420295	48420318	10	-	28162770	SKM1	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	0.6560455987826388	[69]	[194]	6	hSpCas9	negative selection	10527859
48431203	48431226	10	+	28162770	SKM1	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.6135831786609243	[121]	[329]	6	hSpCas9	negative selection	10527860
48431231	48431254	10	+	28162770	SKM1	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.7837193628659482	[114]	[349]	7	hSpCas9	negative selection	10527861
48420278	48420301	10	+	28162770	SKM1	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.5058029632020262	[48]	[122]	5	hSpCas9	negative selection	10527862
48420285	48420308	10	-	28162770	SKM1	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.693539401741671	[148]	[425]	6	hSpCas9	negative selection	10527863
48427117	48427140	10	+	28162770	SKM1	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.3656253051537657	[17]	[40]	3	hSpCas9	negative selection	10697220
48425948	48425971	10	+	28162770	SKM1	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	0.7439776993315779	[50]	[150]	7	hSpCas9	negative selection	10697221
48431259	48431282	10	-	28162770	SKM1	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	0.35857054761981527	[44]	[101]	3	hSpCas9	negative selection	10697222
48420199	48420222	10	+	28162770	SKM1	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	0.1779983019779947	[31]	[63]	1	hSpCas9	negative selection	10697223
48420268	48420291	10	+	28162770	SKM1	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	1.0080733005356821	[35]	[127]	8	hSpCas9	negative selection	10697224
48420295	48420318	10	-	28162770	SKM1	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	0.6560455987826388	[69]	[194]	6	hSpCas9	negative selection	10697225
48431203	48431226	10	+	28162770	SKM1	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.6135831786609243	[121]	[329]	6	hSpCas9	negative selection	10697226
48431231	48431254	10	+	28162770	SKM1	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.7837193628659482	[114]	[349]	7	hSpCas9	negative selection	10697227
48420278	48420301	10	+	28162770	SKM1	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.5058029632020262	[48]	[122]	5	hSpCas9	negative selection	10697228
48420285	48420308	10	-	28162770	SKM1	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.693539401741671	[148]	[425]	6	hSpCas9	negative selection	10697229
48427117	48427140	10	+	28162770	PL21	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.8405972278021799	[67]	[52]	7	hSpCas9	negative selection	10866586
48425948	48425971	10	+	28162770	PL21	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	1.0602819509063597	[183]	[166]	8	hSpCas9	negative selection	10866587
48431259	48431282	10	-	28162770	PL21	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	0.6772988256759616	[124]	[86]	6	hSpCas9	negative selection	10866588
48420199	48420222	10	+	28162770	PL21	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	0.3885847039024305	[85]	[48]	3	hSpCas9	negative selection	10866589
48420268	48420291	10	+	28162770	PL21	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.20147736902720198	[213]	[80]	-1	hSpCas9	negative selection	10866590
48420295	48420318	10	-	28162770	PL21	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	1.4214959890732433	[198]	[231]	9	hSpCas9	negative selection	10866591
48431203	48431226	10	+	28162770	PL21	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	1.0370264062030934	[448]	[400]	8	hSpCas9	negative selection	10866592
48431231	48431254	10	+	28162770	PL21	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.170566499105973	[344]	[168]	1	hSpCas9	negative selection	10866593
48420278	48420301	10	+	28162770	PL21	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	-0.3913955401553223	[219]	[72]	-3	hSpCas9	negative selection	10866594
48420285	48420308	10	-	28162770	PL21	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.6440898056834026	[493]	[335]	5	hSpCas9	negative selection	10866595
48427117	48427140	10	+	28162770	P31FUJ	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.30422581924307535	[50]	[73]	3	hSpCas9	negative selection	11035952
48425948	48425971	10	+	28162770	P31FUJ	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	0.8416969181992118	[216]	[456]	8	hSpCas9	negative selection	11035953
48431259	48431282	10	-	28162770	P31FUJ	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	0.19487950411668786	[141]	[190]	2	hSpCas9	negative selection	11035954
48420199	48420222	10	+	28162770	P31FUJ	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	-0.36900658801269004	[110]	[100]	-3	hSpCas9	negative selection	11035955
48420268	48420291	10	+	28162770	P31FUJ	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.22453458843077806	[173]	[174]	-2	hSpCas9	negative selection	11035956
48420295	48420318	10	-	28162770	P31FUJ	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	0.7358822551194133	[162]	[318]	8	hSpCas9	negative selection	11035957
48431203	48431226	10	+	28162770	P31FUJ	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.5761108720671662	[660]	[1157]	6	hSpCas9	negative selection	11035958
48431231	48431254	10	+	28162770	P31FUJ	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.11671925971683783	[579]	[738]	1	hSpCas9	negative selection	11035959
48420278	48420301	10	+	28162770	P31FUJ	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.33163797243343246	[235]	[348]	3	hSpCas9	negative selection	11035960
48420285	48420308	10	-	28162770	P31FUJ	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.47498019411489123	[798]	[1304]	5	hSpCas9	negative selection	11035961
48427117	48427140	10	+	28162770	OCIAML5	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.6028353892927862	[57]	[158]	5	hSpCas9	negative selection	11205318
48425948	48425971	10	+	28162770	OCIAML5	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	0.5588665300821104	[131]	[350]	5	hSpCas9	negative selection	11205319
48431259	48431282	10	-	28162770	OCIAML5	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	0.01466689827253867	[101]	[185]	0	hSpCas9	negative selection	11205320
48420199	48420222	10	+	28162770	OCIAML5	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	-0.3202154066024031	[82]	[119]	-2	hSpCas9	negative selection	11205321
48420268	48420291	10	+	28162770	OCIAML5	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.6562746482542465	[57]	[164]	6	hSpCas9	negative selection	11205322
48420295	48420318	10	-	28162770	OCIAML5	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	1.1187870834764866	[74]	[293]	8	hSpCas9	negative selection	11205323
48431203	48431226	10	+	28162770	OCIAML5	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	-0.13476430428901276	[457]	[752]	-1	hSpCas9	negative selection	11205324
48431231	48431254	10	+	28162770	OCIAML5	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.20682711818957156	[275]	[574]	1	hSpCas9	negative selection	11205325
48420278	48420301	10	+	28162770	OCIAML5	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	-0.036906246317592484	[157]	[277]	0	hSpCas9	negative selection	11205326
48420285	48420308	10	-	28162770	OCIAML5	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.7701000296858269	[318]	[981]	6	hSpCas9	negative selection	11205327
48427117	48427140	10	+	28162770	EOL1	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.17498790198037995	[134]	[62]	-1	hSpCas9	negative selection	11374684
48425948	48425971	10	+	28162770	EOL1	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	-0.1458415563208636	[230]	[109]	-1	hSpCas9	negative selection	11374685
48431259	48431282	10	-	28162770	EOL1	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	-0.6653135285634608	[294]	[97]	-5	hSpCas9	negative selection	11374686
48420199	48420222	10	+	28162770	EOL1	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	0.21699866538106305	[177]	[108]	2	hSpCas9	negative selection	11374687
48420268	48420291	10	+	28162770	EOL1	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.44815489054995394	[346]	[133]	-3	hSpCas9	negative selection	11374688
48420295	48420318	10	-	28162770	EOL1	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	-0.9007043550136269	[364]	[102]	-6	hSpCas9	negative selection	11374689
48431203	48431226	10	+	28162770	EOL1	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.8333998835123393	[636]	[597]	7	hSpCas9	negative selection	11374690
48431231	48431254	10	+	28162770	EOL1	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	1.1894449214215181	[515]	[619]	8	hSpCas9	negative selection	11374691
48420278	48420301	10	+	28162770	EOL1	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.49045193647600605	[253]	[187]	4	hSpCas9	negative selection	11374692
48420285	48420308	10	-	28162770	EOL1	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	1.0142356591651018	[685]	[729]	8	hSpCas9	negative selection	11374693
48427117	48427140	10	+	28162770	MOLM13	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.2681198691688016	[115]	[100]	2	hSpCas9	negative selection	11544050
48425948	48425971	10	+	28162770	MOLM13	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	-0.3488034050923614	[309]	[175]	-2	hSpCas9	negative selection	11544051
48431259	48431282	10	-	28162770	MOLM13	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	1.7608252730922347	[190]	[467]	9	hSpCas9	negative selection	11544052
48420199	48420222	10	+	28162770	MOLM13	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	0.865544802595186	[166]	[219]	6	hSpCas9	negative selection	11544053
48420268	48420291	10	+	28162770	MOLM13	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	1.7091820082243063	[194]	[460]	9	hSpCas9	negative selection	11544054
48420295	48420318	10	-	28162770	MOLM13	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	0.650894210030881	[243]	[276]	5	hSpCas9	negative selection	11544055
48431203	48431226	10	+	28162770	MOLM13	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.6051944739564814	[660]	[726]	4	hSpCas9	negative selection	11544056
48431231	48431254	10	+	28162770	MOLM13	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	-0.5930786357468482	[579]	[277]	-3	hSpCas9	negative selection	11544057
48420278	48420301	10	+	28162770	MOLM13	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.12474480074752067	[273]	[215]	0	hSpCas9	negative selection	11544058
48420285	48420308	10	-	28162770	MOLM13	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.3960566367835121	[699]	[665]	3	hSpCas9	negative selection	11544059
48427117	48427140	10	+	28162770	HEL	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.3006328551753643	[89]	[70]	2	hSpCas9	negative selection	11713416
48425948	48425971	10	+	28162770	HEL	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	1.0184963436173895	[241]	[313]	8	hSpCas9	negative selection	11713417
48431259	48431282	10	-	28162770	HEL	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	1.1745899962619508	[248]	[359]	8	hSpCas9	negative selection	11713418
48420199	48420222	10	+	28162770	HEL	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	1.0875236746732526	[143]	[195]	8	hSpCas9	negative selection	11713419
48420268	48420291	10	+	28162770	HEL	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	1.1787917322405668	[179]	[260]	9	hSpCas9	negative selection	11713420
48420295	48420318	10	-	28162770	HEL	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	0.7091400577228667	[275]	[288]	6	hSpCas9	negative selection	11713421
48431203	48431226	10	+	28162770	HEL	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	-0.19824982670907776	[574]	[320]	-1	hSpCas9	negative selection	11713422
48431231	48431254	10	+	28162770	HEL	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.14178230653651092	[466]	[329]	1	hSpCas9	negative selection	11713423
48420278	48420301	10	+	28162770	HEL	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	-0.1492681257238111	[186]	[107]	-1	hSpCas9	negative selection	11713424
48420285	48420308	10	-	28162770	HEL	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.10132404695195785	[619]	[425]	0	hSpCas9	negative selection	11713425
48427117	48427140	10	+	28162770	MV411	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-1.7283149029705476	[58]	[14]	-8	hSpCas9	negative selection	11882782
48425948	48425971	10	+	28162770	MV411	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	0.2067955662854293	[143]	[139]	1	hSpCas9	negative selection	11882783
48431259	48431282	10	-	28162770	MV411	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	0.6268511403308978	[122]	[159]	5	hSpCas9	negative selection	11882784
48420199	48420222	10	+	28162770	MV411	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	0.18470179543481258	[93]	[89]	1	hSpCas9	negative selection	11882785
48420268	48420291	10	+	28162770	MV411	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	0.7548390682102786	[120]	[171]	6	hSpCas9	negative selection	11882786
48420295	48420318	10	-	28162770	MV411	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	0.5522921323111963	[220]	[272]	5	hSpCas9	negative selection	11882787
48431203	48431226	10	+	28162770	MV411	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.42099363650084176	[484]	[546]	4	hSpCas9	negative selection	11882788
48431231	48431254	10	+	28162770	MV411	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.7875325293386417	[380]	[553]	7	hSpCas9	negative selection	11882789
48420278	48420301	10	+	28162770	MV411	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.5289513772242295	[180]	[219]	5	hSpCas9	negative selection	11882790
48420285	48420308	10	-	28162770	MV411	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.5693656456701377	[467]	[584]	5	hSpCas9	negative selection	11882791
48427117	48427140	10	+	28162770	MONOMAC1	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-1.472671289672981	[45]	[18]	-8	hSpCas9	negative selection	12052148
48425948	48425971	10	+	28162770	MONOMAC1	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	-0.10187961401921365	[131]	[140]	-1	hSpCas9	negative selection	12052149
48431259	48431282	10	-	28162770	MONOMAC1	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	-0.7882313014922244	[115]	[76]	-6	hSpCas9	negative selection	12052150
48420199	48420222	10	+	28162770	MONOMAC1	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	-0.014833515838804656	[51]	[58]	0	hSpCas9	negative selection	12052151
48420268	48420291	10	+	28162770	MONOMAC1	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.863793438944357	[126]	[79]	-6	hSpCas9	negative selection	12052152
48420295	48420318	10	-	28162770	MONOMAC1	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	-0.6406434985351683	[135]	[99]	-5	hSpCas9	negative selection	12052153
48431203	48431226	10	+	28162770	MONOMAC1	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.7087807138837385	[268]	[503]	6	hSpCas9	negative selection	12052154
48431231	48431254	10	+	28162770	MONOMAC1	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	1.0170879582932937	[224]	[521]	8	hSpCas9	negative selection	12052155
48420278	48420301	10	+	28162770	MONOMAC1	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	-0.001116637084296851	[109]	[125]	0	hSpCas9	negative selection	12052156
48420285	48420308	10	-	28162770	MONOMAC1	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.6050909133345008	[315]	[550]	6	hSpCas9	negative selection	12052157
48427117	48427140	10	+	28162770	OCIAML2	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	-0.13359483796459048	[18]	[95]	-1	hSpCas9	negative selection	12221514
48425948	48425971	10	+	28162770	OCIAML2	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	0.08054436202271156	[35]	[210]	0	hSpCas9	negative selection	12221515
48431259	48431282	10	-	28162770	OCIAML2	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	1.2448642386212203	[21]	[288]	9	hSpCas9	negative selection	12221516
48420199	48420222	10	+	28162770	OCIAML2	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	0.7115735059785876	[12]	[117]	7	hSpCas9	negative selection	12221517
48420268	48420291	10	+	28162770	OCIAML2	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.0876261536030306	[36]	[192]	0	hSpCas9	negative selection	12221518
48420295	48420318	10	-	28162770	OCIAML2	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	-0.317155344580443	[48]	[217]	-3	hSpCas9	negative selection	12221519
48431203	48431226	10	+	28162770	OCIAML2	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.021609483120575756	[82]	[466]	0	hSpCas9	negative selection	12221520
48431231	48431254	10	+	28162770	OCIAML2	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	0.6456073053061628	[72]	[632]	6	hSpCas9	negative selection	12221521
48420278	48420301	10	+	28162770	OCIAML2	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.058989641635220136	[30]	[178]	0	hSpCas9	negative selection	12221522
48420285	48420308	10	-	28162770	OCIAML2	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.5311199567077984	[102]	[824]	5	hSpCas9	negative selection	12221523
48427117	48427140	10	+	28162770	OCIAML3	viability	GGGAACACACAATAGAAGAGTGG	MAPK8	ENSG00000107643	0.7108469412042578	[16]	[83]	6	hSpCas9	negative selection	12390880
48425948	48425971	10	+	28162770	OCIAML3	viability	AGAAACTGCAACCAACAGTAAGG	MAPK8	ENSG00000107643	0.4428291278562083	[28]	[118]	4	hSpCas9	negative selection	12390881
48431259	48431282	10	-	28162770	OCIAML3	viability	TTGTAACCAACCTAAAGGAGAGG	MAPK8	ENSG00000107643	0.2952888952696171	[43]	[162]	2	hSpCas9	negative selection	12390882
48420199	48420222	10	+	28162770	OCIAML3	viability	GAAGATTCTTGACTTCGGTCTGG	MAPK8	ENSG00000107643	-0.3976104275206598	[23]	[54]	-3	hSpCas9	negative selection	12390883
48420268	48420291	10	+	28162770	OCIAML3	viability	TCGCTACTACAGAGCACCCGAGG	MAPK8	ENSG00000107643	-0.11338179941774262	[42]	[119]	-1	hSpCas9	negative selection	12390884
48420295	48420318	10	-	28162770	OCIAML3	viability	TTTCCTTGTAGCCCATGCCAAGG	MAPK8	ENSG00000107643	0.7179363659905772	[57]	[287]	6	hSpCas9	negative selection	12390885
48431203	48431226	10	+	28162770	OCIAML3	viability	TAAGGAAGTTATGGACTTGGAGG	MAPK8	ENSG00000107643	0.35956802258448484	[149]	[580]	3	hSpCas9	negative selection	12390886
48431231	48431254	10	+	28162770	OCIAML3	viability	ACCAAGAATGGAGTTATACGGGG	MAPK8	ENSG00000107643	-0.1667660014581933	[102]	[276]	-1	hSpCas9	negative selection	12390887
48420278	48420301	10	+	28162770	OCIAML3	viability	AGAGCACCCGAGGTCATCCTTGG	MAPK8	ENSG00000107643	0.7458423625604615	[47]	[242]	6	hSpCas9	negative selection	12390888
48420285	48420308	10	-	28162770	OCIAML3	viability	GCCCATGCCAAGGATGACCTCGG	MAPK8	ENSG00000107643	0.7978721379674285	[156]	[823]	7	hSpCas9	negative selection	12390889