Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7867
• Symbol:MAPKAPK3
• Description:MAPK activated protein kinase 3

DataSource: http://genomecrispr.dkfz.de/#!/results/MAPKAPK3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
50617608	50617631	3	-	26472758	Jiyoye	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	1.114994630012563	[179]	[293]	7	hSpCas9	negative selection	96389
50640370	50640393	3	+	26472758	Jiyoye	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	-0.8558590243279205	[287]	[119]	-6	hSpCas9	negative selection	96390
50642317	50642340	3	-	26472758	Jiyoye	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.1634464984688706	[192]	[162]	1	hSpCas9	negative selection	96391
50646753	50646776	3	-	26472758	Jiyoye	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	96392
50646791	50646814	3	-	26472758	Jiyoye	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	0.5051204319178327	[241]	[258]	4	hSpCas9	negative selection	96393
50617565	50617588	3	+	26472758	Jiyoye	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	4.7994928042846325	[0]	[20]	9	hSpCas9	negative selection	96394
50617694	50617717	3	+	26472758	Jiyoye	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	2.014857958727113	[20]	[63]	8	hSpCas9	negative selection	96395
50617721	50617744	3	+	26472758	Jiyoye	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	0.5867248018365863	[82]	[93]	4	hSpCas9	negative selection	96396
50641750	50641773	3	+	26472758	Jiyoye	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-1.6770611556621584	[334]	[78]	-8	hSpCas9	negative selection	96397
50646810	50646833	3	-	26472758	Jiyoye	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	-5.177787119215283	[47]	[0]	-9	hSpCas9	negative selection	96398
50617608	50617631	3	-	26472758	KBM7	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	0.07959528200228771	[798,735]	[360,399]	0	hSpCas9	negative selection	287507
50640370	50640393	3	+	26472758	KBM7	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.30926657141524205	[830,841]	[611,380]	3	hSpCas9	negative selection	287508
50642317	50642340	3	-	26472758	KBM7	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	-0.25346715512675244	[814,612]	[355,209]	-2	hSpCas9	negative selection	287509
50646753	50646776	3	-	26472758	KBM7	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	-2.224017896063634	[71,48]	[5,5]	-8	hSpCas9	negative selection	287510
50646791	50646814	3	-	26472758	KBM7	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	-0.0565673424614247	[1039,927]	[671,240]	0	hSpCas9	negative selection	287511
50617565	50617588	3	+	26472758	KBM7	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	-0.7107333922679908	[127,77]	[28,28]	-5	hSpCas9	negative selection	287512
50617694	50617717	3	+	26472758	KBM7	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	-1.115335241485081	[364,397]	[53,109]	-7	hSpCas9	negative selection	287513
50617721	50617744	3	+	26472758	KBM7	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	0.009625939857719867	[542,624]	[340,224]	0	hSpCas9	negative selection	287514
50641750	50641773	3	+	26472758	KBM7	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.6125841584606577	[523,452]	[325,371]	6	hSpCas9	negative selection	287515
50646810	50646833	3	-	26472758	KBM7	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	-0.037285192343211815	[123,91]	[39,56]	0	hSpCas9	negative selection	287516
50617608	50617631	3	-	26472758	Raji	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	0.4575698903024754	[272]	[86]	4	hSpCas9	negative selection	478625
50640370	50640393	3	+	26472758	Raji	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.17835005672774318	[475]	[124]	1	hSpCas9	negative selection	478626
50642317	50642340	3	-	26472758	Raji	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.7980554772658707	[227]	[91]	7	hSpCas9	negative selection	478627
50646753	50646776	3	-	26472758	Raji	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	-0.6999713866840054	[13]	[1]	-5	hSpCas9	negative selection	478628
50646791	50646814	3	-	26472758	Raji	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	0.615946861341776	[432]	[153]	6	hSpCas9	negative selection	478629
50617565	50617588	3	+	26472758	Raji	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	0.9305057732895201	[51]	[22]	8	hSpCas9	negative selection	478630
50617694	50617717	3	+	26472758	Raji	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	-0.31345958558645015	[165]	[30]	-3	hSpCas9	negative selection	478631
50617721	50617744	3	+	26472758	Raji	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	1.1939712203696902	[193]	[102]	9	hSpCas9	negative selection	478632
50641750	50641773	3	+	26472758	Raji	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-0.6343044690350098	[407]	[60]	-5	hSpCas9	negative selection	478633
50646810	50646833	3	-	26472758	Raji	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	1.657580617934079	[55]	[40]	9	hSpCas9	negative selection	478634
50617608	50617631	3	-	26472758	K562	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	0.6321012680375238	[771]	[1009]	5	hSpCas9	negative selection	669743
50640370	50640393	3	+	26472758	K562	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	-0.6652489526126455	[649]	[345]	-4	hSpCas9	negative selection	669744
50642317	50642340	3	-	26472758	K562	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.33104108241419794	[403]	[428]	2	hSpCas9	negative selection	669745
50646753	50646776	3	-	26472758	K562	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	0.5129075635923486	[43]	[52]	4	hSpCas9	negative selection	669746
50646791	50646814	3	-	26472758	K562	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	0.7431399748824679	[786]	[1111]	6	hSpCas9	negative selection	669747
50617565	50617588	3	+	26472758	K562	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	1.0889642090324676	[92]	[166]	8	hSpCas9	negative selection	669748
50617694	50617717	3	+	26472758	K562	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	0.7552152097507214	[305]	[435]	6	hSpCas9	negative selection	669749
50617721	50617744	3	+	26472758	K562	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	0.4991209154372593	[491]	[586]	4	hSpCas9	negative selection	669750
50641750	50641773	3	+	26472758	K562	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.5745673293587779	[489]	[615]	4	hSpCas9	negative selection	669751
50646810	50646833	3	-	26472758	K562	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	1.4668111490028948	[80]	[188]	9	hSpCas9	negative selection	669752
50617688	50617711	3	+	26627737	DLD1	viability	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	1.0033271186959563	[663]	[576,382,303]	8	hSpCas9	negative selection	822465
50617743	50617766	3	+	26627737	DLD1	viability	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.8669295951159293	[192]	[27,23,44]	-7	hSpCas9	negative selection	822466
50641712	50641735	3	+	26627737	DLD1	viability	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.1313553712780441	[439]	[80,155,138]	-1	hSpCas9	negative selection	822467
50642290	50642313	3	-	26627737	DLD1	viability	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.6263674979501727	[767]	[409,416,297]	6	hSpCas9	negative selection	822468
50646156	50646179	3	-	26627737	DLD1	viability	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.6953875753500253	[471]	[183,311,225]	7	hSpCas9	negative selection	822469
50647920	50647943	3	+	26627737	DLD1	viability	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	0.18430705928961533	[374]	[79,234,94]	1	hSpCas9	negative selection	822470
50617688	50617711	3	+	26627737	GBM cells	viability after 5 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.2348679348835082	[541]	[257,235]	-4	hSpCas9	negative selection	904780
50617743	50617766	3	+	26627737	GBM cells	viability after 5 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.0734116061178216	[69]	[48,29]	1	hSpCas9	negative selection	904781
50641712	50641735	3	+	26627737	GBM cells	viability after 5 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.1317701320544547	[313]	[165,202]	2	hSpCas9	negative selection	904782
50642290	50642313	3	-	26627737	GBM cells	viability after 5 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.15139836137856943	[548]	[318,334]	2	hSpCas9	negative selection	904783
50646156	50646179	3	-	26627737	GBM cells	viability after 5 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.5152994399606444	[438]	[319,352]	7	hSpCas9	negative selection	904784
50647920	50647943	3	+	26627737	GBM cells	viability after 5 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-0.021468957050946424	[140]	[72,75]	0	hSpCas9	negative selection	904785
50617688	50617711	3	+	26627737	GBM cells	viability after 13 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	0.15718263437378277	[541]	[317,335]	2	hSpCas9	negative selection	987095
50617743	50617766	3	+	26627737	GBM cells	viability after 13 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.5084915198166513	[69]	[45,10]	-6	hSpCas9	negative selection	987096
50641712	50641735	3	+	26627737	GBM cells	viability after 13 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.4077552106122009	[313]	[257,199]	5	hSpCas9	negative selection	987097
50642290	50642313	3	-	26627737	GBM cells	viability after 13 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.42863464682708496	[548]	[390,408]	5	hSpCas9	negative selection	987098
50646156	50646179	3	-	26627737	GBM cells	viability after 13 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.604076994617642	[438]	[398,331]	7	hSpCas9	negative selection	987099
50647920	50647943	3	+	26627737	GBM cells	viability after 13 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-0.05201431466151307	[140]	[75,71]	0	hSpCas9	negative selection	987100
50617688	50617711	3	+	26627737	GBM cells	viability after 21 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	0.20587130869689885	[541]	[371,309]	2	hSpCas9	negative selection	1069410
50617743	50617766	3	+	26627737	GBM cells	viability after 21 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.9952284896568488	[69]	[28,9]	-7	hSpCas9	negative selection	1069411
50641712	50641735	3	+	26627737	GBM cells	viability after 21 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.4818440280509184	[313]	[267,210]	5	hSpCas9	negative selection	1069412
50642290	50642313	3	-	26627737	GBM cells	viability after 21 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.5431522087975904	[548]	[478,393]	5	hSpCas9	negative selection	1069413
50646156	50646179	3	-	26627737	GBM cells	viability after 21 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.9194241102387818	[438]	[495,409]	8	hSpCas9	negative selection	1069414
50647920	50647943	3	+	26627737	GBM cells	viability after 21 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	0.17475411586004563	[140]	[98,74]	1	hSpCas9	negative selection	1069415
50617688	50617711	3	+	26627737	RPE1	viability after 9 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	0.30525438212509404	[1337]	[438,618]	2	hSpCas9	negative selection	1151725
50617743	50617766	3	+	26627737	RPE1	viability after 9 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-1.4197453698588842	[372]	[23,68]	-7	hSpCas9	negative selection	1151726
50641712	50641735	3	+	26627737	RPE1	viability after 9 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.17012327121803134	[1058]	[188,430]	-1	hSpCas9	negative selection	1151727
50642290	50642313	3	-	26627737	RPE1	viability after 9 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.41051191490134875	[1542]	[583,716]	3	hSpCas9	negative selection	1151728
50646156	50646179	3	-	26627737	RPE1	viability after 9 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.4028883211943983	[1908]	[663,952]	3	hSpCas9	negative selection	1151729
50647920	50647943	3	+	26627737	RPE1	viability after 9 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-2.3241970286602935	[455]	[0,63]	-9	hSpCas9	negative selection	1151730
50617688	50617711	3	+	26627737	RPE1	viability after 12 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	0.6483379253519842	[1337]	[611,511]	4	hSpCas9	negative selection	1234040
50617743	50617766	3	+	26627737	RPE1	viability after 12 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.8640625692313453	[372]	[73,34]	-5	hSpCas9	negative selection	1234041
50641712	50641735	3	+	26627737	RPE1	viability after 12 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.9861765055687982	[1058]	[96,192]	-6	hSpCas9	negative selection	1234042
50642290	50642313	3	-	26627737	RPE1	viability after 12 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.5969106979044418	[1542]	[677,572]	4	hSpCas9	negative selection	1234043
50646156	50646179	3	-	26627737	RPE1	viability after 12 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.2713722129940297	[1908]	[534,707]	1	hSpCas9	negative selection	1234044
50647920	50647943	3	+	26627737	RPE1	viability after 12 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-2.0436938064081156	[455]	[53,3]	-8	hSpCas9	negative selection	1234045
50617688	50617711	3	+	26627737	RPE1	viability after 15 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	0.49172711923999535	[1337]	[604,461]	3	hSpCas9	negative selection	1316355
50617743	50617766	3	+	26627737	RPE1	viability after 15 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-1.199993398814874	[372]	[49,41]	-6	hSpCas9	negative selection	1316356
50641712	50641735	3	+	26627737	RPE1	viability after 15 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.22398661195796668	[1058]	[228,282]	-1	hSpCas9	negative selection	1316357
50642290	50642313	3	-	26627737	RPE1	viability after 15 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.7782943338273984	[1542]	[854,645]	5	hSpCas9	negative selection	1316358
50646156	50646179	3	-	26627737	RPE1	viability after 15 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.5828246078881163	[1908]	[846,771]	3	hSpCas9	negative selection	1316359
50647920	50647943	3	+	26627737	RPE1	viability after 15 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-6.417500748499694	[455]	[0,1]	-9	hSpCas9	negative selection	1316360
50617688	50617711	3	+	26627737	RPE1	viability after 18 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	0.7481978782173423	[1337]	[533,683]	4	hSpCas9	negative selection	1398670
50617743	50617766	3	+	26627737	RPE1	viability after 18 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.9697203163020438	[372]	[62,38]	-6	hSpCas9	negative selection	1398671
50641712	50641735	3	+	26627737	RPE1	viability after 18 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.4679103777623989	[1058]	[122,295]	-3	hSpCas9	negative selection	1398672
50642290	50642313	3	-	26627737	RPE1	viability after 18 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.6009418241048998	[1542]	[618,644]	4	hSpCas9	negative selection	1398673
50646156	50646179	3	-	26627737	RPE1	viability after 18 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.49416724775493925	[1908]	[714,736]	3	hSpCas9	negative selection	1398674
50647920	50647943	3	+	26627737	RPE1	viability after 18 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-1.8251171546742404	[455]	[55,11]	-8	hSpCas9	negative selection	1398675
50617688	50617711	3	+	26627737	HeLa	viability after 8 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.24767829238091288	[699]	[357,177,255]	-2	hSpCas9	negative selection	1480985
50617743	50617766	3	+	26627737	HeLa	viability after 8 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.3596250227297221	[198]	[42,129,26]	-4	hSpCas9	negative selection	1480986
50641712	50641735	3	+	26627737	HeLa	viability after 8 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	1.2504229705546608	[290]	[291,445,172]	8	hSpCas9	negative selection	1480987
50642290	50642313	3	-	26627737	HeLa	viability after 8 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	-0.12754361277308846	[919]	[501,257,368]	-1	hSpCas9	negative selection	1480988
50646156	50646179	3	-	26627737	HeLa	viability after 8 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.33254101283682935	[765]	[523,410,351]	3	hSpCas9	negative selection	1480989
50647920	50647943	3	+	26627737	HeLa	viability after 8 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	1.641960497307502	[96]	[117,65,202]	9	hSpCas9	negative selection	1480990
50617688	50617711	3	+	26627737	HeLa	viability after 12 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	0.3177944181129575	[699]	[302,360,415]	2	hSpCas9	negative selection	1563300
50617743	50617766	3	+	26627737	HeLa	viability after 12 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.20371817834129946	[198]	[123,87,1]	-2	hSpCas9	negative selection	1563301
50641712	50641735	3	+	26627737	HeLa	viability after 12 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	1.6956821467796597	[290]	[224,548,372]	9	hSpCas9	negative selection	1563302
50642290	50642313	3	-	26627737	HeLa	viability after 12 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	-0.08796137308374297	[919]	[416,280,384]	0	hSpCas9	negative selection	1563303
50646156	50646179	3	-	26627737	HeLa	viability after 12 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.35938760243701884	[765]	[342,457,409]	3	hSpCas9	negative selection	1563304
50647920	50647943	3	+	26627737	HeLa	viability after 12 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	1.1020345889052519	[96]	[70,54,134]	7	hSpCas9	negative selection	1563305
50617688	50617711	3	+	26627737	HeLa	viability after 15 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.11188305218082717	[699]	[294,288,201]	-1	hSpCas9	negative selection	1645615
50617743	50617766	3	+	26627737	HeLa	viability after 15 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-1.1365006914674396	[198]	[21,84,0]	-7	hSpCas9	negative selection	1645616
50641712	50641735	3	+	26627737	HeLa	viability after 15 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	1.3249224381761147	[290]	[222,350,318]	8	hSpCas9	negative selection	1645617
50642290	50642313	3	-	26627737	HeLa	viability after 15 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	-0.3603796765081829	[919]	[348,263,258]	-3	hSpCas9	negative selection	1645618
50646156	50646179	3	-	26627737	HeLa	viability after 15 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	1.0167155478056669	[765]	[368,729,810]	7	hSpCas9	negative selection	1645619
50647920	50647943	3	+	26627737	HeLa	viability after 15 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	1.2628600133237	[96]	[204,65,4]	8	hSpCas9	negative selection	1645620
50617688	50617711	3	+	26627737	HeLa	viability after 18 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.08175406996153234	[699]	[208,238,201]	0	hSpCas9	negative selection	1727930
50617743	50617766	3	+	26627737	HeLa	viability after 18 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-1.0292262383240516	[198]	[14,76,0]	-7	hSpCas9	negative selection	1727931
50641712	50641735	3	+	26627737	HeLa	viability after 18 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	1.3195760872351865	[290]	[135,304,318]	8	hSpCas9	negative selection	1727932
50642290	50642313	3	-	26627737	HeLa	viability after 18 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	-0.34230811812035944	[919]	[240,218,258]	-3	hSpCas9	negative selection	1727933
50646156	50646179	3	-	26627737	HeLa	viability after 18 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	1.0193533539181123	[765]	[258,592,810]	7	hSpCas9	negative selection	1727934
50647920	50647943	3	+	26627737	HeLa	viability after 18 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	1.2871666818500518	[96]	[137,57,4]	8	hSpCas9	negative selection	1727935
50617688	50617711	3	+	26627737	HCT116	viability after 6 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	0.06546553832335911	[1395]	[199,245]	0	hSpCas9	negative selection	1810245
50617743	50617766	3	+	26627737	HCT116	viability after 6 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-3.9619280147956673	[380]	[8,0]	-9	hSpCas9	negative selection	1810246
50641712	50641735	3	+	26627737	HCT116	viability after 6 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.18318147064287899	[700]	[127,79]	-1	hSpCas9	negative selection	1810247
50642290	50642313	3	-	26627737	HCT116	viability after 6 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	-1.0842668585819693	[1270]	[139,68]	-6	hSpCas9	negative selection	1810248
50646156	50646179	3	-	26627737	HCT116	viability after 6 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.518029449053858	[1188]	[257,272]	3	hSpCas9	negative selection	1810249
50647920	50647943	3	+	26627737	HCT116	viability after 6 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	0.3150660720861281	[584]	[310,5]	1	hSpCas9	negative selection	1810250
50617688	50617711	3	+	26627737	HCT116	viability after 8 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.1432306252665425	[642]	[331,336,293]	-2	hSpCas9	negative selection	1892560
50617743	50617766	3	+	26627737	HCT116	viability after 8 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.7047687450188934	[179]	[34,77,68]	-7	hSpCas9	negative selection	1892561
50641712	50641735	3	+	26627737	HCT116	viability after 8 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.04144531868343648	[389]	[213,241,170]	0	hSpCas9	negative selection	1892562
50642290	50642313	3	-	26627737	HCT116	viability after 8 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	-0.11973050933150065	[651]	[324,346,319]	-1	hSpCas9	negative selection	1892563
50646156	50646179	3	-	26627737	HCT116	viability after 8 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	-0.026918420731973924	[699]	[378,396,359]	0	hSpCas9	negative selection	1892564
50647920	50647943	3	+	26627737	HCT116	viability after 8 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-0.23660075985440965	[189]	[113,61,90]	-3	hSpCas9	negative selection	1892565
50617688	50617711	3	+	26627737	HCT116	viability after 9 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	0.5115267604255225	[1395]	[913,228]	4	hSpCas9	negative selection	1974875
50617743	50617766	3	+	26627737	HCT116	viability after 9 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.5869400424469425	[380]	[55,76]	-4	hSpCas9	negative selection	1974876
50641712	50641735	3	+	26627737	HCT116	viability after 9 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.2533289715686785	[700]	[170,145]	-2	hSpCas9	negative selection	1974877
50642290	50642313	3	-	26627737	HCT116	viability after 9 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	-0.29531732456589455	[1270]	[337,227]	-2	hSpCas9	negative selection	1974878
50646156	50646179	3	-	26627737	HCT116	viability after 9 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	-0.07908414080420645	[1188]	[404,217]	0	hSpCas9	negative selection	1974879
50647920	50647943	3	+	26627737	HCT116	viability after 9 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	0.05919076485240169	[584]	[64,239]	0	hSpCas9	negative selection	1974880
50617688	50617711	3	+	26627737	HCT116	viability after 12 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.19122944643788287	[642]	[360,370,151]	-2	hSpCas9	negative selection	2057190
50617743	50617766	3	+	26627737	HCT116	viability after 12 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-1.2188131546798937	[179]	[13,70,39]	-8	hSpCas9	negative selection	2057191
50641712	50641735	3	+	26627737	HCT116	viability after 12 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.3026479662762321	[389]	[192,267,302]	3	hSpCas9	negative selection	2057192
50642290	50642313	3	-	26627737	HCT116	viability after 12 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	-0.2126186744700721	[651]	[357,270,251]	-2	hSpCas9	negative selection	2057193
50646156	50646179	3	-	26627737	HCT116	viability after 12 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.06328575269681957	[699]	[262,476,425]	0	hSpCas9	negative selection	2057194
50647920	50647943	3	+	26627737	HCT116	viability after 12 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-0.36959062899673223	[189]	[59,61,110]	-4	hSpCas9	negative selection	2057195
50617688	50617711	3	+	26627737	HCT116	viability after 15 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.23301947371504528	[642]	[376,322,250]	-2	hSpCas9	negative selection	2139505
50617743	50617766	3	+	26627737	HCT116	viability after 15 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-1.102548404566292	[179]	[57,70,16]	-8	hSpCas9	negative selection	2139506
50641712	50641735	3	+	26627737	HCT116	viability after 15 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.18411261111945718	[389]	[211,164,215]	-2	hSpCas9	negative selection	2139507
50642290	50642313	3	-	26627737	HCT116	viability after 15 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	-0.3937839511326472	[651]	[402,234,231]	-4	hSpCas9	negative selection	2139508
50646156	50646179	3	-	26627737	HCT116	viability after 15 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.08787006865920066	[699]	[558,328,409]	0	hSpCas9	negative selection	2139509
50647920	50647943	3	+	26627737	HCT116	viability after 15 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	0.376719890907854	[189]	[231,143,60]	3	hSpCas9	negative selection	2139510
50617688	50617711	3	+	26627737	HCT116	viability after 18 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.060367090377888566	[642]	[393,141,371]	0	hSpCas9	negative selection	2221820
50617743	50617766	3	+	26627737	HCT116	viability after 18 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.10156439838178499	[179]	[111,137,23]	0	hSpCas9	negative selection	2221821
50641712	50641735	3	+	26627737	HCT116	viability after 18 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.030528158683428452	[389]	[207,138,210]	0	hSpCas9	negative selection	2221822
50642290	50642313	3	-	26627737	HCT116	viability after 18 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.03905957967676743	[651]	[413,308,245]	0	hSpCas9	negative selection	2221823
50646156	50646179	3	-	26627737	HCT116	viability after 18 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	-0.41471485834368804	[699]	[289,209,264]	-4	hSpCas9	negative selection	2221824
50647920	50647943	3	+	26627737	HCT116	viability after 18 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	0.5661312870894306	[189]	[140,150,113]	5	hSpCas9	negative selection	2221825
50617564	50617587	3	-	24336569	HL60	viability	CTCTGCTGTTTCACCATCCATGG	MAPKAPK3	ENSG00000114738	0.7436801348722359	[402]	[1427]	6	hSpCas9	negative selection	2276210
50617571	50617594	3	+	24336569	HL60	viability	TGGTGAAACAGCAGAGGAGCAGG	MAPKAPK3	ENSG00000114738	0.437171469492156	[726]	[2082]	4	hSpCas9	negative selection	2276211
50617607	50617630	3	-	24336569	HL60	viability	GTCCGCCGGGTGCAACTGGCGGG	MAPKAPK3	ENSG00000114738	-0.35964505021655546	[1148]	[1894]	-3	hSpCas9	negative selection	2276212
50617616	50617639	3	+	24336569	HL60	viability	TGCACCCGGCGGACCCGGCTTGG	MAPKAPK3	ENSG00000114738	0.6267797405254518	[623]	[2038]	5	hSpCas9	negative selection	2276213
50617621	50617644	3	-	24336569	HL60	viability	ACCGCCCAAGCCGGGTCCGCCGG	MAPKAPK3	ENSG00000114738	0.40647394569739526	[327]	[919]	4	hSpCas9	negative selection	2276214
50617628	50617651	3	+	24336569	HL60	viability	ACCCGGCTTGGGCGGTGCTCCGG	MAPKAPK3	ENSG00000114738	0.7221386865676003	[274]	[959]	6	hSpCas9	negative selection	2276215
50617665	50617688	3	-	24336569	HL60	viability	TCGGTCACTGCGTACTTCTTGGG	MAPKAPK3	ENSG00000114738	0.7766926721462754	[282]	[1025]	6	hSpCas9	negative selection	2276216
50617684	50617707	3	-	24336569	HL60	viability	CTTGGACAACTGGTAGTCGTCGG	MAPKAPK3	ENSG00000114738	0.35204605872142625	[1260]	[3405]	3	hSpCas9	negative selection	2276217
50617694	50617717	3	-	24336569	HL60	viability	CCAGCACCTGCTTGGACAACTGG	MAPKAPK3	ENSG00000114738	0.8692683544544073	[416]	[1611]	7	hSpCas9	negative selection	2276218
50617700	50617723	3	+	24336569	HL60	viability	GTCCAAGCAGGTGCTGGGCCTGG	MAPKAPK3	ENSG00000114738	-0.5212788634529053	[2446]	[3607]	-5	hSpCas9	negative selection	2276219
50617564	50617587	3	-	24336569	KBM7	viability	CTCTGCTGTTTCACCATCCATGG	MAPKAPK3	ENSG00000114738	1.0205148057564433	[316]	[1753]	8	hSpCas9	negative selection	2343387
50617571	50617594	3	+	24336569	KBM7	viability	TGGTGAAACAGCAGAGGAGCAGG	MAPKAPK3	ENSG00000114738	0.06590679081805573	[530]	[1515]	0	hSpCas9	negative selection	2343388
50617607	50617630	3	-	24336569	KBM7	viability	GTCCGCCGGGTGCAACTGGCGGG	MAPKAPK3	ENSG00000114738	0.8568690388336474	[464]	[2296]	7	hSpCas9	negative selection	2343389
50617616	50617639	3	+	24336569	KBM7	viability	TGCACCCGGCGGACCCGGCTTGG	MAPKAPK3	ENSG00000114738	0.28368027927210754	[455]	[1513]	2	hSpCas9	negative selection	2343390
50617621	50617644	3	-	24336569	KBM7	viability	ACCGCCCAAGCCGGGTCCGCCGG	MAPKAPK3	ENSG00000114738	0.6295251994301251	[295]	[1248]	6	hSpCas9	negative selection	2343391
50617628	50617651	3	+	24336569	KBM7	viability	ACCCGGCTTGGGCGGTGCTCCGG	MAPKAPK3	ENSG00000114738	0.5688152417017861	[174]	[707]	5	hSpCas9	negative selection	2343392
50617665	50617688	3	-	24336569	KBM7	viability	TCGGTCACTGCGTACTTCTTGGG	MAPKAPK3	ENSG00000114738	0.6521044381365535	[324]	[1392]	6	hSpCas9	negative selection	2343393
50617684	50617707	3	-	24336569	KBM7	viability	CTTGGACAACTGGTAGTCGTCGG	MAPKAPK3	ENSG00000114738	0.2152446729908397	[1075]	[3406]	2	hSpCas9	negative selection	2343394
50617694	50617717	3	-	24336569	KBM7	viability	CCAGCACCTGCTTGGACAACTGG	MAPKAPK3	ENSG00000114738	1.3884505251464265	[305]	[2184]	9	hSpCas9	negative selection	2343395
50617700	50617723	3	+	24336569	KBM7	viability	GTCCAAGCAGGTGCTGGGCCTGG	MAPKAPK3	ENSG00000114738	0.49998902898030706	[1498]	[5781]	4	hSpCas9	negative selection	2343396
50611703	50611726	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGGAGGGAACCAGTGGGCGCGG	MAPKAPK3	ENSG00000114738	-0.2943033759297822	[2,15]	[1,0]	-1	dCas9-VP64	positive selection	2415154
50611727	50611750	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCGTGCTGGGTAGGCTCCCGG	MAPKAPK3	ENSG00000114738	1.885790859483151	[12,42]	[9,36]	6	dCas9-VP64	positive selection	2415155
50611680	50611703	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGACTCGGCTGGACGGCGGCGG	MAPKAPK3	ENSG00000114738	1.9009768474718398	[0,1]	[0,0]	6	dCas9-VP64	positive selection	2415156
50616970	50616993	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCGGAACAAAATAGGAGGCGTGG	MAPKAPK3	ENSG00000114738	3.838888670567633	[0,14]	[1,52]	9	dCas9-VP64	positive selection	2436301
50616942	50616965	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGGGGGCGGTTACTTCCTCGG	MAPKAPK3	ENSG00000114738	-0.9986465733858022	[348,37]	[12,27]	-6	dCas9-VP64	positive selection	2436302
50617040	50617063	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCAACTTGGGGCCCCGCTAGG	MAPKAPK3	ENSG00000114738	1.1702890636045964	[309,189]	[117,129]	4	dCas9-VP64	positive selection	2436303
50611991	50612014	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGATTTCCAAGAACTTTCCAGG	MAPKAPK3	ENSG00000114738	-0.2046406582144391	[88,273]	[24,44]	-1	dCas9-VP64	positive selection	2442758
50611940	50611963	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGCCCCGTCGCCGGGTCTGGGG	MAPKAPK3	ENSG00000114738	3.9490460151395737	[227,24]	[425,428]	9	dCas9-VP64	positive selection	2442759
50611963	50611986	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTATTTCCTTTCACTGCTCAGGG	MAPKAPK3	ENSG00000114738	1.5392944977832022	[77,23]	[28,35]	6	dCas9-VP64	positive selection	2442760
50611703	50611726	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGGAGGGAACCAGTGGGCGCGG	MAPKAPK3	ENSG00000114738	0.5325138693430637	[50,64]	[13,38]	4	dCas9-VP64	positive selection	2510409
50611727	50611750	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCGTGCTGGGTAGGCTCCCGG	MAPKAPK3	ENSG00000114738	3.270896463462158	[24,66]	[24,256]	9	dCas9-VP64	positive selection	2510410
50611680	50611703	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGACTCGGCTGGACGGCGGCGG	MAPKAPK3	ENSG00000114738	-0.7935048466292827	[103,3]	[16,2]	-7	dCas9-VP64	positive selection	2510411
50616970	50616993	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCGGAACAAAATAGGAGGCGTGG	MAPKAPK3	ENSG00000114738	0.09516602880100877	[38,13]	[5,11]	0	dCas9-VP64	positive selection	2531556
50616942	50616965	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGGGGGCGGTTACTTCCTCGG	MAPKAPK3	ENSG00000114738	0.8723529524657083	[21,14]	[8,12]	6	dCas9-VP64	positive selection	2531557
50617040	50617063	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCAACTTGGGGCCCCGCTAGG	MAPKAPK3	ENSG00000114738	1.8309559152185684	[111,236]	[12,377]	8	dCas9-VP64	positive selection	2531558
50611991	50612014	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGATTTCCAAGAACTTTCCAGG	MAPKAPK3	ENSG00000114738	-0.5936246061588965	[92,110]	[26,15]	-6	dCas9-VP64	positive selection	2538013
50611940	50611963	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGCCCCGTCGCCGGGTCTGGGG	MAPKAPK3	ENSG00000114738	-1.1485315711664814	[10,202]	[6,22]	-9	dCas9-VP64	positive selection	2538014
50611963	50611986	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTATTTCCTTTCACTGCTCAGGG	MAPKAPK3	ENSG00000114738	-0.024493743750523933	[225,87]	[55,44]	0	dCas9-VP64	positive selection	2538015
50617607	50617630	3	-	27260157	DLD1	viability	GTCCGCCGGGTGCAACTGGCGGG	MAPKAPK3	ENSG00000114738	-0.859033261047472	[]	[]	-6	hSpCas9	negative selection	2575670
50617665	50617688	3	-	27260157	DLD1	viability	TCGGTCACTGCGTACTTCTTGGG	MAPKAPK3	ENSG00000114738	-1.10008369241793	[]	[]	-7	hSpCas9	negative selection	2577306
50617616	50617639	3	+	27260157	DLD1	viability	TGCACCCGGCGGACCCGGCTTGG	MAPKAPK3	ENSG00000114738	0.423445167277507	[]	[]	7	hSpCas9	negative selection	2577651
50617700	50617723	3	+	27260157	DLD1	viability	GTCCAAGCAGGTGCTGGGCCTGG	MAPKAPK3	ENSG00000114738	0.0438531804725892	[]	[]	3	hSpCas9	negative selection	2577805
50617571	50617594	3	+	27260157	DLD1	viability	TGGTGAAACAGCAGAGGAGCAGG	MAPKAPK3	ENSG00000114738	0.952038461231115	[]	[]	9	hSpCas9	negative selection	2578707
50617628	50617651	3	+	27260157	DLD1	viability	ACCCGGCTTGGGCGGTGCTCCGG	MAPKAPK3	ENSG00000114738	-0.650544527420376	[]	[]	-5	hSpCas9	negative selection	2580792
50617621	50617644	3	-	27260157	DLD1	viability	ACCGCCCAAGCCGGGTCCGCCGG	MAPKAPK3	ENSG00000114738	-0.155472621165966	[]	[]	-1	hSpCas9	negative selection	2585117
50617751	50617774	3	-	27260157	DLD1	viability	ACTTCTGTCCAGTGCGCCGATGG	MAPKAPK3	ENSG00000114738	-0.804747478032337	[]	[]	-6	hSpCas9	negative selection	2586953
50617684	50617707	3	-	27260157	DLD1	viability	CTTGGACAACTGGTAGTCGTCGG	MAPKAPK3	ENSG00000114738	0.275224884831024	[]	[]	4	hSpCas9	negative selection	2606506
50640446	50640469	3	-	27260157	DLD1	viability	GCATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	1.17595411730268	[]	[]	9	hSpCas9	negative selection	2606686
50617735	50617758	3	+	27260157	DLD1	viability	AAGTGCTGGAGTGCTTCCATCGG	MAPKAPK3	ENSG00000114738	-0.192474307138851	[]	[]	-1	hSpCas9	negative selection	2615071
50617694	50617717	3	-	27260157	DLD1	viability	CCAGCACCTGCTTGGACAACTGG	MAPKAPK3	ENSG00000114738	0.406639086757132	[]	[]	4	hSpCas9	negative selection	2621932
50642316	50642339	3	-	27260157	DLD1	viability	CCTCACCTTGACATCTCGGTGGG	MAPKAPK3	ENSG00000114738	0.302003847643329	[]	[]	4	hSpCas9	negative selection	2621979
50641712	50641735	3	+	27260157	DLD1	viability	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.229309187457899	[]	[]	3	hSpCas9	negative selection	2624239
50644448	50644471	3	+	27260157	DLD1	viability	GTGCTTAAGCTCACCGATTTTGG	MAPKAPK3	ENSG00000114738	0.0624050066884081	[]	[]	3	hSpCas9	negative selection	2643570
50617606	50617629	3	-	27260157	DLD1	viability	TCCGCCGGGTGCAACTGGCGGGG	MAPKAPK3	ENSG00000114738	-0.405505947882411	[]	[]	-3	hSpCas9	negative selection	2645921
50642305	50642328	3	-	27260157	DLD1	viability	CATCTCGGTGGGCAATGTTATGG	MAPKAPK3	ENSG00000114738	-0.0798456484365078	[]	[]	0	hSpCas9	negative selection	2646464
50617564	50617587	3	-	27260157	DLD1	viability	CTCTGCTGTTTCACCATCCATGG	MAPKAPK3	ENSG00000114738	1.14692867884423	[]	[]	9	hSpCas9	negative selection	2647604
50617607	50617630	3	-	27260157	HT1080	viability	GTCCGCCGGGTGCAACTGGCGGG	MAPKAPK3	ENSG00000114738	0.170466024131445	[]	[]	1	hSpCas9	negative selection	2651800
50617665	50617688	3	-	27260157	HT1080	viability	TCGGTCACTGCGTACTTCTTGGG	MAPKAPK3	ENSG00000114738	-2.17714053509489	[]	[]	-9	hSpCas9	negative selection	2653436
50617616	50617639	3	+	27260157	HT1080	viability	TGCACCCGGCGGACCCGGCTTGG	MAPKAPK3	ENSG00000114738	-0.0735447923937579	[]	[]	0	hSpCas9	negative selection	2653781
50617700	50617723	3	+	27260157	HT1080	viability	GTCCAAGCAGGTGCTGGGCCTGG	MAPKAPK3	ENSG00000114738	0.0117042532173527	[]	[]	0	hSpCas9	negative selection	2653935
50617571	50617594	3	+	27260157	HT1080	viability	TGGTGAAACAGCAGAGGAGCAGG	MAPKAPK3	ENSG00000114738	0.324260187218172	[]	[]	3	hSpCas9	negative selection	2654837
50617628	50617651	3	+	27260157	HT1080	viability	ACCCGGCTTGGGCGGTGCTCCGG	MAPKAPK3	ENSG00000114738	-0.645297717650273	[]	[]	-8	hSpCas9	negative selection	2656922
50617621	50617644	3	-	27260157	HT1080	viability	ACCGCCCAAGCCGGGTCCGCCGG	MAPKAPK3	ENSG00000114738	0.143748935250357	[]	[]	1	hSpCas9	negative selection	2661247
50617751	50617774	3	-	27260157	HT1080	viability	ACTTCTGTCCAGTGCGCCGATGG	MAPKAPK3	ENSG00000114738	-0.594287442695939	[]	[]	-7	hSpCas9	negative selection	2663083
50617684	50617707	3	-	27260157	HT1080	viability	CTTGGACAACTGGTAGTCGTCGG	MAPKAPK3	ENSG00000114738	0.333227463243001	[]	[]	3	hSpCas9	negative selection	2682636
50640446	50640469	3	-	27260157	HT1080	viability	GCATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	-0.805983903261667	[]	[]	-8	hSpCas9	negative selection	2682816
50617735	50617758	3	+	27260157	HT1080	viability	AAGTGCTGGAGTGCTTCCATCGG	MAPKAPK3	ENSG00000114738	-0.00232831255176116	[]	[]	0	hSpCas9	negative selection	2691201
50617694	50617717	3	-	27260157	HT1080	viability	CCAGCACCTGCTTGGACAACTGG	MAPKAPK3	ENSG00000114738	0.683126308010796	[]	[]	6	hSpCas9	negative selection	2698062
50642316	50642339	3	-	27260157	HT1080	viability	CCTCACCTTGACATCTCGGTGGG	MAPKAPK3	ENSG00000114738	0.146565013886448	[]	[]	1	hSpCas9	negative selection	2698109
50641712	50641735	3	+	27260157	HT1080	viability	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.91019748017014	[]	[]	7	hSpCas9	negative selection	2700369
50644448	50644471	3	+	27260157	HT1080	viability	GTGCTTAAGCTCACCGATTTTGG	MAPKAPK3	ENSG00000114738	0.706835387139867	[]	[]	6	hSpCas9	negative selection	2719700
50617606	50617629	3	-	27260157	HT1080	viability	TCCGCCGGGTGCAACTGGCGGGG	MAPKAPK3	ENSG00000114738	-0.81179098010995	[]	[]	-8	hSpCas9	negative selection	2722051
50642305	50642328	3	-	27260157	HT1080	viability	CATCTCGGTGGGCAATGTTATGG	MAPKAPK3	ENSG00000114738	-0.00976658432686293	[]	[]	0	hSpCas9	negative selection	2722594
50617564	50617587	3	-	27260157	HT1080	viability	CTCTGCTGTTTCACCATCCATGG	MAPKAPK3	ENSG00000114738	1.76836764591017	[]	[]	9	hSpCas9	negative selection	2723734
50617607	50617630	3	-	27260157	MKN45	viability	GTCCGCCGGGTGCAACTGGCGGG	MAPKAPK3	ENSG00000114738	-0.327592571370091	[]	[]	-1	hSpCas9	negative selection	2727930
50617665	50617688	3	-	27260157	MKN45	viability	TCGGTCACTGCGTACTTCTTGGG	MAPKAPK3	ENSG00000114738	-2.15144188901778	[]	[]	-9	hSpCas9	negative selection	2729566
50617616	50617639	3	+	27260157	MKN45	viability	TGCACCCGGCGGACCCGGCTTGG	MAPKAPK3	ENSG00000114738	0.939684594338041	[]	[]	8	hSpCas9	negative selection	2729911
50617700	50617723	3	+	27260157	MKN45	viability	GTCCAAGCAGGTGCTGGGCCTGG	MAPKAPK3	ENSG00000114738	0.774678258114725	[]	[]	7	hSpCas9	negative selection	2730065
50617571	50617594	3	+	27260157	MKN45	viability	TGGTGAAACAGCAGAGGAGCAGG	MAPKAPK3	ENSG00000114738	0.846320099227398	[]	[]	8	hSpCas9	negative selection	2730967
50617628	50617651	3	+	27260157	MKN45	viability	ACCCGGCTTGGGCGGTGCTCCGG	MAPKAPK3	ENSG00000114738	0.677135547680665	[]	[]	7	hSpCas9	negative selection	2733052
50617621	50617644	3	-	27260157	MKN45	viability	ACCGCCCAAGCCGGGTCCGCCGG	MAPKAPK3	ENSG00000114738	-0.0472739365812206	[]	[]	0	hSpCas9	negative selection	2737377
50617751	50617774	3	-	27260157	MKN45	viability	ACTTCTGTCCAGTGCGCCGATGG	MAPKAPK3	ENSG00000114738	-0.515186564761646	[]	[]	-6	hSpCas9	negative selection	2739213
50617684	50617707	3	-	27260157	MKN45	viability	CTTGGACAACTGGTAGTCGTCGG	MAPKAPK3	ENSG00000114738	-0.170930791432916	[]	[]	0	hSpCas9	negative selection	2758766
50640446	50640469	3	-	27260157	MKN45	viability	GCATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	-1.56395940386025	[]	[]	-9	hSpCas9	negative selection	2758946
50617735	50617758	3	+	27260157	MKN45	viability	AAGTGCTGGAGTGCTTCCATCGG	MAPKAPK3	ENSG00000114738	0.452387748760281	[]	[]	6	hSpCas9	negative selection	2767331
50617694	50617717	3	-	27260157	MKN45	viability	CCAGCACCTGCTTGGACAACTGG	MAPKAPK3	ENSG00000114738	0.632908924781211	[]	[]	7	hSpCas9	negative selection	2774192
50642316	50642339	3	-	27260157	MKN45	viability	CCTCACCTTGACATCTCGGTGGG	MAPKAPK3	ENSG00000114738	0.123889819356774	[]	[]	4	hSpCas9	negative selection	2774239
50641712	50641735	3	+	27260157	MKN45	viability	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.404814838651953	[]	[]	6	hSpCas9	negative selection	2776499
50644448	50644471	3	+	27260157	MKN45	viability	GTGCTTAAGCTCACCGATTTTGG	MAPKAPK3	ENSG00000114738	0.394069772700675	[]	[]	6	hSpCas9	negative selection	2795830
50617606	50617629	3	-	27260157	MKN45	viability	TCCGCCGGGTGCAACTGGCGGGG	MAPKAPK3	ENSG00000114738	0.461139766912696	[]	[]	6	hSpCas9	negative selection	2798181
50642305	50642328	3	-	27260157	MKN45	viability	CATCTCGGTGGGCAATGTTATGG	MAPKAPK3	ENSG00000114738	-1.0110207021458	[]	[]	-8	hSpCas9	negative selection	2798724
50617564	50617587	3	-	27260157	MKN45	viability	CTCTGCTGTTTCACCATCCATGG	MAPKAPK3	ENSG00000114738	0.108734445536006	[]	[]	4	hSpCas9	negative selection	2799864
50617607	50617630	3	-	27260157	RKO	viability	GTCCGCCGGGTGCAACTGGCGGG	MAPKAPK3	ENSG00000114738	0.135473245217362	[]	[]	0	hSpCas9	negative selection	2804060
50617665	50617688	3	-	27260157	RKO	viability	TCGGTCACTGCGTACTTCTTGGG	MAPKAPK3	ENSG00000114738	-1.60935080988401	[]	[]	-9	hSpCas9	negative selection	2805696
50617616	50617639	3	+	27260157	RKO	viability	TGCACCCGGCGGACCCGGCTTGG	MAPKAPK3	ENSG00000114738	-0.258717549815368	[]	[]	-1	hSpCas9	negative selection	2806041
50617700	50617723	3	+	27260157	RKO	viability	GTCCAAGCAGGTGCTGGGCCTGG	MAPKAPK3	ENSG00000114738	-0.112776992352886	[]	[]	0	hSpCas9	negative selection	2806195
50617571	50617594	3	+	27260157	RKO	viability	TGGTGAAACAGCAGAGGAGCAGG	MAPKAPK3	ENSG00000114738	0.195989191309268	[]	[]	1	hSpCas9	negative selection	2807097
50617628	50617651	3	+	27260157	RKO	viability	ACCCGGCTTGGGCGGTGCTCCGG	MAPKAPK3	ENSG00000114738	-0.730983314751422	[]	[]	-7	hSpCas9	negative selection	2809182
50617621	50617644	3	-	27260157	RKO	viability	ACCGCCCAAGCCGGGTCCGCCGG	MAPKAPK3	ENSG00000114738	0.0406503683981656	[]	[]	0	hSpCas9	negative selection	2813507
50617751	50617774	3	-	27260157	RKO	viability	ACTTCTGTCCAGTGCGCCGATGG	MAPKAPK3	ENSG00000114738	-1.28526596864957	[]	[]	-8	hSpCas9	negative selection	2815343
50617684	50617707	3	-	27260157	RKO	viability	CTTGGACAACTGGTAGTCGTCGG	MAPKAPK3	ENSG00000114738	0.201276063461302	[]	[]	1	hSpCas9	negative selection	2834896
50640446	50640469	3	-	27260157	RKO	viability	GCATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	-0.472706633362271	[]	[]	-6	hSpCas9	negative selection	2835076
50617735	50617758	3	+	27260157	RKO	viability	AAGTGCTGGAGTGCTTCCATCGG	MAPKAPK3	ENSG00000114738	0.957973686427619	[]	[]	8	hSpCas9	negative selection	2843461
50617694	50617717	3	-	27260157	RKO	viability	CCAGCACCTGCTTGGACAACTGG	MAPKAPK3	ENSG00000114738	0.611933022423994	[]	[]	3	hSpCas9	negative selection	2850322
50642316	50642339	3	-	27260157	RKO	viability	CCTCACCTTGACATCTCGGTGGG	MAPKAPK3	ENSG00000114738	-0.262184283877241	[]	[]	-1	hSpCas9	negative selection	2850369
50641712	50641735	3	+	27260157	RKO	viability	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.159543562011843	[]	[]	0	hSpCas9	negative selection	2852629
50644448	50644471	3	+	27260157	RKO	viability	GTGCTTAAGCTCACCGATTTTGG	MAPKAPK3	ENSG00000114738	0.424072184015771	[]	[]	2	hSpCas9	negative selection	2871960
50617606	50617629	3	-	27260157	RKO	viability	TCCGCCGGGTGCAACTGGCGGGG	MAPKAPK3	ENSG00000114738	-0.31416441921271	[]	[]	-6	hSpCas9	negative selection	2874311
50642305	50642328	3	-	27260157	RKO	viability	CATCTCGGTGGGCAATGTTATGG	MAPKAPK3	ENSG00000114738	0.0131950808317048	[]	[]	0	hSpCas9	negative selection	2874854
50617564	50617587	3	-	27260157	RKO	viability	CTCTGCTGTTTCACCATCCATGG	MAPKAPK3	ENSG00000114738	0.75354416448255	[]	[]	8	hSpCas9	negative selection	2875994
50617607	50617630	3	-	27260157	SF268	viability	GTCCGCCGGGTGCAACTGGCGGG	MAPKAPK3	ENSG00000114738	0.258594567513733	[]	[]	4	hSpCas9	negative selection	2880190
50617665	50617688	3	-	27260157	SF268	viability	TCGGTCACTGCGTACTTCTTGGG	MAPKAPK3	ENSG00000114738	-1.87377118313888	[]	[]	-8	hSpCas9	negative selection	2881826
50617616	50617639	3	+	27260157	SF268	viability	TGCACCCGGCGGACCCGGCTTGG	MAPKAPK3	ENSG00000114738	-0.0865518901587974	[]	[]	0	hSpCas9	negative selection	2882171
50617700	50617723	3	+	27260157	SF268	viability	GTCCAAGCAGGTGCTGGGCCTGG	MAPKAPK3	ENSG00000114738	0.512586670709518	[]	[]	7	hSpCas9	negative selection	2882325
50617571	50617594	3	+	27260157	SF268	viability	TGGTGAAACAGCAGAGGAGCAGG	MAPKAPK3	ENSG00000114738	0.163640599949845	[]	[]	0	hSpCas9	negative selection	2883227
50617628	50617651	3	+	27260157	SF268	viability	ACCCGGCTTGGGCGGTGCTCCGG	MAPKAPK3	ENSG00000114738	-0.15304857352151	[]	[]	-1	hSpCas9	negative selection	2885312
50617621	50617644	3	-	27260157	SF268	viability	ACCGCCCAAGCCGGGTCCGCCGG	MAPKAPK3	ENSG00000114738	0.123836229210602	[]	[]	0	hSpCas9	negative selection	2889637
50617751	50617774	3	-	27260157	SF268	viability	ACTTCTGTCCAGTGCGCCGATGG	MAPKAPK3	ENSG00000114738	-1.46562598235113	[]	[]	-8	hSpCas9	negative selection	2891473
50617684	50617707	3	-	27260157	SF268	viability	CTTGGACAACTGGTAGTCGTCGG	MAPKAPK3	ENSG00000114738	-0.247003556123015	[]	[]	-2	hSpCas9	negative selection	2911026
50640446	50640469	3	-	27260157	SF268	viability	GCATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	-0.180472648190552	[]	[]	-1	hSpCas9	negative selection	2911206
50617735	50617758	3	+	27260157	SF268	viability	AAGTGCTGGAGTGCTTCCATCGG	MAPKAPK3	ENSG00000114738	-0.401850997496228	[]	[]	-3	hSpCas9	negative selection	2919591
50617694	50617717	3	-	27260157	SF268	viability	CCAGCACCTGCTTGGACAACTGG	MAPKAPK3	ENSG00000114738	0.933150834041893	[]	[]	9	hSpCas9	negative selection	2926452
50642316	50642339	3	-	27260157	SF268	viability	CCTCACCTTGACATCTCGGTGGG	MAPKAPK3	ENSG00000114738	0.195141834961072	[]	[]	3	hSpCas9	negative selection	2926499
50641712	50641735	3	+	27260157	SF268	viability	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.58897275958359	[]	[]	-4	hSpCas9	negative selection	2928759
50644448	50644471	3	+	27260157	SF268	viability	GTGCTTAAGCTCACCGATTTTGG	MAPKAPK3	ENSG00000114738	0.507668407164822	[]	[]	7	hSpCas9	negative selection	2948090
50617606	50617629	3	-	27260157	SF268	viability	TCCGCCGGGTGCAACTGGCGGGG	MAPKAPK3	ENSG00000114738	-0.175252621535081	[]	[]	-1	hSpCas9	negative selection	2950441
50642305	50642328	3	-	27260157	SF268	viability	CATCTCGGTGGGCAATGTTATGG	MAPKAPK3	ENSG00000114738	0.235173474495073	[]	[]	3	hSpCas9	negative selection	2950984
50617564	50617587	3	-	27260157	SF268	viability	CTCTGCTGTTTCACCATCCATGG	MAPKAPK3	ENSG00000114738	-0.195541258809707	[]	[]	-1	hSpCas9	negative selection	2952124
50640428	50640451	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGGATGCAGACAATATGGGGG	MAPKAPK3	ENSG00000114738	0.0980320550776197	[4,3]	[3,3]	2	hSpCas9	positive selection	3001301
50617576	50617599	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAAACAGCAGAGGAGCAGGGGGG	MAPKAPK3	ENSG00000114738	0.22213961605281296	[2,3]	[1,4]	5	hSpCas9	positive selection	3001302
50617718	50617741	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACTTTGCCGTTCACACCCAGG	MAPKAPK3	ENSG00000114738	0.16625899446591652	[5,5]	[5,4]	3	hSpCas9	positive selection	3001303
50640366	50640389	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCTGTATGACAGCCCCAAGG	MAPKAPK3	ENSG00000114738	0.007554902514830021	[3,3]	[3,2]	0	hSpCas9	positive selection	3001304
50640428	50640451	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGGATGCAGACAATATGGGGG	MAPKAPK3	ENSG00000114738	0.39304174635353895	[4,4]	[4,3]	6	hSpCas9	positive selection	3069159
50617576	50617599	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAAACAGCAGAGGAGCAGGGGGG	MAPKAPK3	ENSG00000114738	-0.3844083618949393	[2,2]	[2,0]	-5	hSpCas9	positive selection	3069160
50617718	50617741	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACTTTGCCGTTCACACCCAGG	MAPKAPK3	ENSG00000114738	-0.03751145745731921	[5,5]	[4,2]	0	hSpCas9	positive selection	3069161
50640366	50640389	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCTGTATGACAGCCCCAAGG	MAPKAPK3	ENSG00000114738	-0.20152055612604391	[3,3]	[3,0]	-3	hSpCas9	positive selection	3069162
50645737	50645760		+	24336571	A375	resistance to PLX after 7 days	ATGACAAGTCATGTGACATGTGG	MAPKAPK3	ENSG00000114738	0.14440190623726973	[14,15]	[17,15]	4	hSpCas9	positive selection	3126436
50645727	50645750		-	24336571	A375	resistance to PLX after 7 days	CATGACTTGTCATACTTCTCTGG	MAPKAPK3	ENSG00000114738	-0.11758090166900337	[21,18]	[19,17]	-4	hSpCas9	positive selection	3126437
50645702	50645725		+	24336571	A375	resistance to PLX after 7 days	CCTGGCAGCCCCTGAGGTCCTGG	MAPKAPK3	ENSG00000114738	0.22398168031589888	[16,17]	[21,17]	6	hSpCas9	positive selection	3126439
50646759	50646782		-	24336571	A375	resistance to PLX after 7 days	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.26539501731464477	[11,11]	[11,16]	7	hSpCas9	positive selection	3126440
50645737	50645760		+	24336571	A375	resistance to PLX after 14 days	ATGACAAGTCATGTGACATGTGG	MAPKAPK3	ENSG00000114738	0.3989447211680659	[10,18]	[8,8]	4	hSpCas9	positive selection	3184229
50645727	50645750		-	24336571	A375	resistance to PLX after 14 days	CATGACTTGTCATACTTCTCTGG	MAPKAPK3	ENSG00000114738	-0.8517691323272248	[29,15]	[5,4]	-8	hSpCas9	positive selection	3184230
50645702	50645725		+	24336571	A375	resistance to PLX after 14 days	CCTGGCAGCCCCTGAGGTCCTGG	MAPKAPK3	ENSG00000114738	-0.43314706094544875	[15,16]	[5,4]	-5	hSpCas9	positive selection	3184232
50646759	50646782		-	24336571	A375	resistance to PLX after 14 days	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	1.3344860621102401	[12,16]	[20,14]	8	hSpCas9	positive selection	3184233
50645737	50645760		+	24336571	A375	viability after 7 days	ATGACAAGTCATGTGACATGTGG	MAPKAPK3	ENSG00000114738	0.316243002553594	[12]	[14,15]	5	hSpCas9	negative selection	3242022
50645727	50645750		-	24336571	A375	viability after 7 days	CATGACTTGTCATACTTCTCTGG	MAPKAPK3	ENSG00000114738	0.34841375281467546	[16]	[21,18]	5	hSpCas9	negative selection	3242023
50645702	50645725		+	24336571	A375	viability after 7 days	CCTGGCAGCCCCTGAGGTCCTGG	MAPKAPK3	ENSG00000114738	-0.7854372496863822	[31]	[16,17]	-8	hSpCas9	negative selection	3242025
50646759	50646782		-	24336571	A375	viability after 7 days	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	-0.012502034907016568	[12]	[11,11]	0	hSpCas9	negative selection	3242026
50645737	50645760		+	24336571	A375	viability after 14 days	ATGACAAGTCATGTGACATGTGG	MAPKAPK3	ENSG00000114738	0.26858349620685384	[12]	[10,18]	3	hSpCas9	negative selection	3299815
50645727	50645750		-	24336571	A375	viability after 14 days	CATGACTTGTCATACTTCTCTGG	MAPKAPK3	ENSG00000114738	0.5059203732148708	[16]	[29,15]	6	hSpCas9	negative selection	3299816
50645702	50645725		+	24336571	A375	viability after 14 days	CCTGGCAGCCCCTGAGGTCCTGG	MAPKAPK3	ENSG00000114738	-0.8091326512959377	[31]	[15,16]	-7	hSpCas9	negative selection	3299818
50646759	50646782		-	24336571	A375	viability after 14 days	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.35877812003846876	[12]	[12,16]	4	hSpCas9	negative selection	3299819
50640381	50640404	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.20204377594464537	[132,132]	[0,0]	1	hSpCas9	positive selection	3378528
50641750	50641773	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-0.0735906666687818	[160,160]	[0,0]	0	hSpCas9	positive selection	3378529
50641752	50641775	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	-1.553245423295312	[448,448]	[0,0]	-8	hSpCas9	positive selection	3378530
50640428	50640451	3	-	26780180	HT29	viability (Avana library 4 designs)	CCAGGATGCAGACAATATGGGGG	MAPKAPK3	ENSG00000114738	0.408003015099691	[]	[]	1	hSpCas9	negative selection	3438947
50617575	50617598	3	+	26780180	HT29	viability (Avana library 4 designs)	GAAACAGCAGAGGAGCAGGGGGG	MAPKAPK3	ENSG00000114738	4.72810431235658	[]	[]	9	hSpCas9	negative selection	3438948
50617718	50617741	3	-	26780180	HT29	viability (Avana library 4 designs)	GCACTTTGCCGTTCACACCCAGG	MAPKAPK3	ENSG00000114738	-0.301990003870881	[]	[]	-5	hSpCas9	negative selection	3438949
50640365	50640388	3	+	26780180	HT29	viability (Avana library 4 designs)	GCTCCTGTATGACAGCCCCAAGG	MAPKAPK3	ENSG00000114738	0.788157935715845	[]	[]	3	hSpCas9	negative selection	3438950
50640365	50640388	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCTGTATGACAGCCCCAAGG	MAPKAPK3	ENSG00000114738	2.3182475223452	[]	[]	3	hSpCas9	negative selection	3528450
50640428	50640451	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGGATGCAGACAATATGGGGG	MAPKAPK3	ENSG00000114738	3.39619173272844	[]	[]	5	hSpCas9	negative selection	3528451
50617718	50617741	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACTTTGCCGTTCACACCCAGG	MAPKAPK3	ENSG00000114738	6.21193476598324	[]	[]	9	hSpCas9	negative selection	3528452
50617575	50617598	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAAACAGCAGAGGAGCAGGGGGG	MAPKAPK3	ENSG00000114738	-3.85849086354357	[]	[]	-4	hSpCas9	negative selection	3528453
50617684	50617707	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGGACAACTGGTAGTCGTCGG	MAPKAPK3	ENSG00000114738	1.74514154330394	[]	[]	2	hSpCas9	negative selection	3528454
50617632	50617655	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTTGGGCGGTGCTCCGGGGGG	MAPKAPK3	ENSG00000114738	5.27788093054052	[]	[]	8	hSpCas9	negative selection	3528455
50640365	50640388	3	+	26780180	A375	viability (Avana lentiGuide)	GCTCCTGTATGACAGCCCCAAGG	MAPKAPK3	ENSG00000114738	-5.62739611574292	[]	[]	-8	hSpCas9	negative selection	3637109
50640428	50640451	3	-	26780180	A375	viability (Avana lentiGuide)	CCAGGATGCAGACAATATGGGGG	MAPKAPK3	ENSG00000114738	-5.00085246358751	[]	[]	-8	hSpCas9	negative selection	3637110
50617718	50617741	3	-	26780180	A375	viability (Avana lentiGuide)	GCACTTTGCCGTTCACACCCAGG	MAPKAPK3	ENSG00000114738	-2.54850670286506	[]	[]	-4	hSpCas9	negative selection	3637111
50617575	50617598	3	+	26780180	A375	viability (Avana lentiGuide)	GAAACAGCAGAGGAGCAGGGGGG	MAPKAPK3	ENSG00000114738	12.7502943679953	[]	[]	7	hSpCas9	negative selection	3637112
50617684	50617707	3	-	26780180	A375	viability (Avana lentiGuide)	CTTGGACAACTGGTAGTCGTCGG	MAPKAPK3	ENSG00000114738	-2.10668794364169	[]	[]	-4	hSpCas9	negative selection	3637113
50617632	50617655	3	+	26780180	A375	viability (Avana lentiGuide)	GGCTTGGGCGGTGCTCCGGGGGG	MAPKAPK3	ENSG00000114738	4.14018911674142	[]	[]	4	hSpCas9	negative selection	3637114
50640365	50640388	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCTGTATGACAGCCCCAAGG	MAPKAPK3	ENSG00000114738	0.02303060694622823	[5]	[4,5]	0	hSpCas9	positive selection	3745768
50640428	50640451	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGGATGCAGACAATATGGGGG	MAPKAPK3	ENSG00000114738	-0.09258266620399738	[5]	[5,3]	-1	hSpCas9	positive selection	3745769
50617718	50617741	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACTTTGCCGTTCACACCCAGG	MAPKAPK3	ENSG00000114738	0.14819749376018823	[5]	[6,5]	4	hSpCas9	positive selection	3745770
50617575	50617598	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAACAGCAGAGGAGCAGGGGGG	MAPKAPK3	ENSG00000114738	0.04624557986428761	[4]	[4,5]	1	hSpCas9	positive selection	3745771
50617684	50617707	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGGACAACTGGTAGTCGTCGG	MAPKAPK3	ENSG00000114738	0.1913661816758945	[4]	[5,5]	5	hSpCas9	positive selection	3745772
50617632	50617655	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTTGGGCGGTGCTCCGGGGGG	MAPKAPK3	ENSG00000114738	0.2766449986191645	[3]	[4,4]	7	hSpCas9	positive selection	3745773
50640365	50640388	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCTGTATGACAGCCCCAAGG	MAPKAPK3	ENSG00000114738	0.035029608972096594	[5]	[4,4]	0	hSpCas9	positive selection	3854375
50640428	50640451	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGGATGCAGACAATATGGGGG	MAPKAPK3	ENSG00000114738	-0.2821780200997621	[5]	[3,3]	-4	hSpCas9	positive selection	3854376
50617718	50617741	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACTTTGCCGTTCACACCCAGG	MAPKAPK3	ENSG00000114738	0.22995370028197615	[7]	[7,6]	6	hSpCas9	positive selection	3854377
50617575	50617598	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAACAGCAGAGGAGCAGGGGGG	MAPKAPK3	ENSG00000114738	-0.4365459961425143	[5]	[2,3]	-5	hSpCas9	positive selection	3854378
50617684	50617707	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGGACAACTGGTAGTCGTCGG	MAPKAPK3	ENSG00000114738	0.06720061673388694	[5]	[5,4]	1	hSpCas9	positive selection	3854379
50617632	50617655	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTTGGGCGGTGCTCCGGGGGG	MAPKAPK3	ENSG00000114738	0.09282233586587901	[4]	[3,4]	2	hSpCas9	positive selection	3854380
50640404	50640427	3	-	26780180	A375	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	1.36350849103661	[]	[]	7	hSpCas9	negative selection	3959903
50646759	50646782	3	-	26780180	A375	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	1.62176126114779	[]	[]	8	hSpCas9	negative selection	3959904
50641750	50641773	3	+	26780180	A375	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.571591124761768	[]	[]	1	hSpCas9	negative selection	3959905
50646814	50646837	3	-	26780180	A375	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	1.04850009667687	[]	[]	5	hSpCas9	negative selection	3959906
50641752	50641775	3	-	26780180	A375	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.797668909045141	[]	[]	3	hSpCas9	negative selection	3959907
50640381	50640404	3	-	26780180	A375	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.514511970049609	[]	[]	1	hSpCas9	negative selection	3959908
50640404	50640427	3	-	26780180	HT29	viability (GeCKOv2 library)	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.809156189751462	[]	[]	3	hSpCas9	negative selection	4067869
50646759	50646782	3	-	26780180	HT29	viability (GeCKOv2 library)	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.532532879087123	[]	[]	1	hSpCas9	negative selection	4067870
50641750	50641773	3	+	26780180	HT29	viability (GeCKOv2 library)	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.999027744392901	[]	[]	4	hSpCas9	negative selection	4067871
50646814	50646837	3	-	26780180	HT29	viability (GeCKOv2 library)	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.876382769248986	[]	[]	3	hSpCas9	negative selection	4067872
50641752	50641775	3	-	26780180	HT29	viability (GeCKOv2 library)	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.94605494995898	[]	[]	4	hSpCas9	negative selection	4067873
50640381	50640404	3	-	26780180	HT29	viability (GeCKOv2 library)	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	1.10535105871432	[]	[]	5	hSpCas9	negative selection	4067874
50611623	50611646	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	0.38528588873925407	[0]	[0,0]	8	hSpCas9	positive selection	4127881
50645737	50645760	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGACAAGTCATGTGACATGTGG	MAPKAPK3	ENSG00000114738	0.5979408279510338	[3]	[5,3]	9	hSpCas9	positive selection	4150656
50645727	50645750	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATGACTTGTCATACTTCTCTGG	MAPKAPK3	ENSG00000114738	1.0191692439141735	[3]	[8,2]	9	hSpCas9	positive selection	4150657
50645702	50645725	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGGCAGCCCCTGAGGTCCTGG	MAPKAPK3	ENSG00000114738	-0.20156780831306	[4]	[2,2]	-5	hSpCas9	positive selection	4150659
50646759	50646782	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.43319510785539567	[3]	[2,4]	8	hSpCas9	positive selection	4150660
50611623	50611646	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.663240544126736	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4191903
50645737	50645760	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGACAAGTCATGTGACATGTGG	MAPKAPK3	ENSG00000114738	-0.40597106669953276	[3]	[2,0,0,0]	-6	hSpCas9	positive selection	4214678
50645727	50645750	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATGACTTGTCATACTTCTCTGG	MAPKAPK3	ENSG00000114738	0.50528140541241	[4]	[3,3,5,0]	3	hSpCas9	positive selection	4214679
50645702	50645725	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGGCAGCCCCTGAGGTCCTGG	MAPKAPK3	ENSG00000114738	-0.5000461696169318	[4]	[1,0,2,0]	-7	hSpCas9	positive selection	4214681
50646759	50646782	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	1.2866822917199303	[3]	[3,3,4,2]	9	hSpCas9	positive selection	4214682
50646814	50646837	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.07309771532900952	[2]	[2,1]	1	hSpCas9	positive selection	4281963
50646759	50646782	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	-0.08425272328284177	[2]	[2,1]	-2	hSpCas9	positive selection	4281964
50640404	50640427	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	-0.36842205571887543	[3]	[2,0]	-7	hSpCas9	positive selection	4281965
50611623	50611646	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	0.21912812338842963	[3]	[3,2]	4	hSpCas9	positive selection	4327706
50611632	50611655	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.2196032622069872	[3]	[4,2]	4	hSpCas9	positive selection	4327707
50640381	50640404	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.14312813306082223	[2]	[2,1]	3	hSpCas9	positive selection	4346221
50641750	50641773	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.17984761745306269	[2]	[2,1]	3	hSpCas9	positive selection	4346222
50641752	50641775	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.11466670733733336	[3]	[4,2]	2	hSpCas9	positive selection	4346223
50617744	50617766	3	+	27760321	OCIAML3	viability	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.14015867530333193	[744,647]	[384,633]	-1	hSpCas9	negative selection	4416805
50640446	50640468	3	-	27760321	OCIAML3	viability	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	0.04814459805239946	[265,222]	[235,145]	0	hSpCas9	negative selection	4416806
50642317	50642339	3	-	27760321	OCIAML3	viability	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.6115356555253565	[874,756]	[810,1182]	7	hSpCas9	negative selection	4416807
50644405	50644427	3	-	27760321	OCIAML3	viability	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	-0.8463722997150999	[395,336]	[144,176]	-7	hSpCas9	negative selection	4416808
50644461	50644483	3	-	27760321	OCIAML3	viability	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	0.5376142959612857	[87,58]	[64,104]	6	hSpCas9	negative selection	4416809
50617744	50617766	3	+	27760321	OCIAML2	viability	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.07582191373477598	[744,647]	[512,696]	1	hSpCas9	negative selection	4500268
50640446	50640468	3	-	27760321	OCIAML2	viability	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	-0.276913900292981	[265,222]	[115,223]	-3	hSpCas9	negative selection	4500269
50642317	50642339	3	-	27760321	OCIAML2	viability	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.029202460726073576	[874,756]	[509,884]	0	hSpCas9	negative selection	4500270
50644405	50644427	3	-	27760321	OCIAML2	viability	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	0.6133520360241113	[395,336]	[401,517]	8	hSpCas9	negative selection	4500271
50644461	50644483	3	-	27760321	OCIAML2	viability	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	-0.4414468564593035	[87,58]	[31,57]	-5	hSpCas9	negative selection	4500272
50617744	50617766	3	+	27760321	MV411	viability	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.19796718720101292	[744,647]	[212,995]	1	hSpCas9	negative selection	4583731
50640446	50640468	3	-	27760321	MV411	viability	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	0.12718629444374352	[265,222]	[81,315]	0	hSpCas9	negative selection	4583732
50642317	50642339	3	-	27760321	MV411	viability	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.9981807917337685	[874,756]	[1493,439]	7	hSpCas9	negative selection	4583733
50644405	50644427	3	-	27760321	MV411	viability	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	0.28558850681030057	[395,336]	[314,261]	2	hSpCas9	negative selection	4583734
50644461	50644483	3	-	27760321	MV411	viability	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	-2.85979666431012	[87,58]	[0,14]	-9	hSpCas9	negative selection	4583735
50617744	50617766	3	+	27760321	HL60	viability	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.18527840491423342	[744,647]	[454,545]	-2	hSpCas9	negative selection	4667194
50640446	50640468	3	-	27760321	HL60	viability	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	0.27977174334857224	[265,222]	[241,240]	3	hSpCas9	negative selection	4667195
50642317	50642339	3	-	27760321	HL60	viability	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.2695495198372816	[874,756]	[730,875]	3	hSpCas9	negative selection	4667196
50644405	50644427	3	-	27760321	HL60	viability	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	-0.0825564618089712	[395,336]	[274,288]	-1	hSpCas9	negative selection	4667197
50644461	50644483	3	-	27760321	HL60	viability	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	-0.2891424094332029	[87,58]	[31,65]	-3	hSpCas9	negative selection	4667198
50617744	50617766	3	+	27760321	HT1080	viability	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.7098185756005538	[647,505]	[35,254]	-3	hSpCas9	negative selection	4750657
50640446	50640468	3	-	27760321	HT1080	viability	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	-1.877138660133959	[222,173]	[0,43]	-6	hSpCas9	negative selection	4750658
50642317	50642339	3	-	27760321	HT1080	viability	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	1.2129481721338633	[756,590]	[504,750]	6	hSpCas9	negative selection	4750659
50644405	50644427	3	-	27760321	HT1080	viability	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	-0.8800210311127994	[336,262]	[31,100]	-4	hSpCas9	negative selection	4750660
50644461	50644483	3	-	27760321	HT1080	viability	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	2.3909502224888337	[58,45]	[197,12]	9	hSpCas9	negative selection	4750661
50617744	50617766	3	+	27760321	HT29	viability after 7 days	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.30304386684509743	[647,505]	[992,763,995]	4	hSpCas9	negative selection	4834120
50640446	50640468	3	-	27760321	HT29	viability after 7 days	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	0.2607376200678734	[222,173]	[279,289,341]	4	hSpCas9	negative selection	4834121
50642317	50642339	3	-	27760321	HT29	viability after 7 days	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.2965717743097742	[756,590]	[1253,849,1112]	4	hSpCas9	negative selection	4834122
50644405	50644427	3	-	27760321	HT29	viability after 7 days	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	-0.05315335426611789	[336,262]	[308,526,272]	-1	hSpCas9	negative selection	4834123
50644461	50644483	3	-	27760321	HT29	viability after 7 days	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	-1.0067757783412072	[58,45]	[31,50,17]	-8	hSpCas9	negative selection	4834124
50617744	50617766	3	+	27760321	HT29	viability after 25 days	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.20963681507074505	[647,505]	[621,715,979]	2	hSpCas9	negative selection	4917583
50640446	50640468	3	-	27760321	HT29	viability after 25 days	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	0.03416590681839082	[222,173]	[263,236,188]	0	hSpCas9	negative selection	4917584
50642317	50642339	3	-	27760321	HT29	viability after 25 days	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.8122126655246495	[756,590]	[1199,1289,1600]	8	hSpCas9	negative selection	4917585
50644405	50644427	3	-	27760321	HT29	viability after 25 days	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	0.1699113741822143	[336,262]	[195,426,563]	1	hSpCas9	negative selection	4917586
50644461	50644483	3	-	27760321	HT29	viability after 25 days	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	0.29971875565746586	[58,45]	[76,80,61]	3	hSpCas9	negative selection	4917587
50617744	50617766	3	+	27760321	HT29	viability after 22 days	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.34144282357463085	[647,505]	[911,745,875]	3	hSpCas9	negative selection	5001046
50640446	50640468	3	-	27760321	HT29	viability after 22 days	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	0.2791627600303167	[222,173]	[260,384,188]	3	hSpCas9	negative selection	5001047
50642317	50642339	3	-	27760321	HT29	viability after 22 days	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.8225376393071144	[756,590]	[1361,1437,1333]	8	hSpCas9	negative selection	5001048
50644405	50644427	3	-	27760321	HT29	viability after 22 days	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	0.13201328336008522	[336,262]	[322,507,309]	1	hSpCas9	negative selection	5001049
50644461	50644483	3	-	27760321	HT29	viability after 22 days	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	-0.12660519283886496	[58,45]	[30,125,9]	-1	hSpCas9	negative selection	5001050
50617744	50617766	3	+	27760321	HT29	viability after 19 days	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.5413698771415397	[647,505]	[761,980,1110]	5	hSpCas9	negative selection	5084509
50640446	50640468	3	-	27760321	HT29	viability after 19 days	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	0.5558986669433916	[222,173]	[602,114,311]	5	hSpCas9	negative selection	5084510
50642317	50642339	3	-	27760321	HT29	viability after 19 days	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.6843754551971619	[756,590]	[1253,954,1497]	7	hSpCas9	negative selection	5084511
50644405	50644427	3	-	27760321	HT29	viability after 19 days	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	0.45896376323989957	[336,262]	[444,689,283]	4	hSpCas9	negative selection	5084512
50644461	50644483	3	-	27760321	HT29	viability after 19 days	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	-0.08976777425438787	[58,45]	[63,102,4]	-1	hSpCas9	negative selection	5084513
50617744	50617766	3	+	27760321	HT29	viability after 16 days	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.040817406643647636	[647,505]	[781,752,465]	0	hSpCas9	negative selection	5167972
50640446	50640468	3	-	27760321	HT29	viability after 16 days	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	0.41127968466781706	[222,173]	[291,319,272]	4	hSpCas9	negative selection	5167973
50642317	50642339	3	-	27760321	HT29	viability after 16 days	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.49156031191017746	[756,590]	[1036,956,1186]	5	hSpCas9	negative selection	5167974
50644405	50644427	3	-	27760321	HT29	viability after 16 days	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	0.2955256221411805	[336,262]	[370,560,295]	3	hSpCas9	negative selection	5167975
50644461	50644483	3	-	27760321	HT29	viability after 16 days	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	1.012864636231354	[58,45]	[64,136,147]	9	hSpCas9	negative selection	5167976
50617744	50617766	3	+	27760321	HT29	viability after 13 days	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.48493721990219474	[647,505]	[1303,883,639]	6	hSpCas9	negative selection	5251435
50640446	50640468	3	-	27760321	HT29	viability after 13 days	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	0.24478755282724973	[222,173]	[147,400,269]	3	hSpCas9	negative selection	5251436
50642317	50642339	3	-	27760321	HT29	viability after 13 days	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.6589402128561193	[756,590]	[1053,1210,1426]	8	hSpCas9	negative selection	5251437
50644405	50644427	3	-	27760321	HT29	viability after 13 days	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	0.5203298200392801	[336,262]	[677,438,386]	6	hSpCas9	negative selection	5251438
50644461	50644483	3	-	27760321	HT29	viability after 13 days	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	0.8408846458531041	[58,45]	[76,135,113]	9	hSpCas9	negative selection	5251439
50617744	50617766	3	+	27760321	HT29	viability after 10 days	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.03562148664240694	[647,505]	[721,600,884]	0	hSpCas9	negative selection	5334898
50640446	50640468	3	-	27760321	HT29	viability after 10 days	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	-0.3788057394275456	[222,173]	[219,221,131]	-5	hSpCas9	negative selection	5334899
50642317	50642339	3	-	27760321	HT29	viability after 10 days	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.345716785182824	[756,590]	[1188,833,1175]	5	hSpCas9	negative selection	5334900
50644405	50644427	3	-	27760321	HT29	viability after 10 days	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	0.18171009096673768	[336,262]	[388,551,338]	2	hSpCas9	negative selection	5334901
50644461	50644483	3	-	27760321	HT29	viability after 10 days	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	0.4262729916143857	[58,45]	[109,93,60]	6	hSpCas9	negative selection	5334902
50617744	50617766	3	+	27760321	MOLM13	viability	AGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.35936132454774433	[744,647]	[196,397]	-2	hSpCas9	negative selection	5418361
50640446	50640468	3	-	27760321	MOLM13	viability	CATGTTCTCATACACATCCAGG	MAPKAPK3	ENSG00000114738	0.058534788957965156	[265,222]	[235,63]	0	hSpCas9	negative selection	5418362
50642317	50642339	3	-	27760321	MOLM13	viability	CCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.4453204316347382	[874,756]	[951,346]	3	hSpCas9	negative selection	5418363
50644405	50644427	3	-	27760321	MOLM13	viability	GTAGAGTAGGTTTTCAGGCTGG	MAPKAPK3	ENSG00000114738	1.0536312926071858	[395,336]	[860,58]	7	hSpCas9	negative selection	5418364
50644461	50644483	3	-	27760321	MOLM13	viability	TCCTTAGCAAAGCCAAAATCGG	MAPKAPK3	ENSG00000114738	-5.355190506387651	[87,58]	[0,0]	-9	hSpCas9	negative selection	5418365
50611677	50611700	3	+	27661255	K562	viability	GTGGGGACTCGGCTGGACGGCGG	MAPKAPK3	ENSG00000114738	0.2041990791420759	[1112,1479]	[1348,1048]	7	dCas9-KRAB	negative selection	5471078
50611698	50611721	3	+	27661255	K562	viability	GGCGGCTGGAGGGAACCAGTGGG	MAPKAPK3	ENSG00000114738	-0.17062698540527	[872,805]	[587,603]	-5	dCas9-KRAB	negative selection	5471079
50611720	50611743	3	+	27661255	K562	viability	GCGCGGAGCGCGTGCTGGGTAGG	MAPKAPK3	ENSG00000114738	-0.04968986859402624	[453,611]	[467,358]	-2	dCas9-KRAB	negative selection	5471080
50611729	50611752	3	+	27661255	K562	viability	GCGTGCTGGGTAGGCTCCCGGGG	MAPKAPK3	ENSG00000114738	0.29755539022115696	[254,261]	[264,243]	8	dCas9-KRAB	negative selection	5471081
50611749	50611772	3	+	27661255	K562	viability	GGGCGCGCGGGCGCAGGACAGGG	MAPKAPK3	ENSG00000114738	-0.46552008484527396	[1145,1070]	[600,676]	-7	dCas9-KRAB	negative selection	5471082
50611758	50611781	3	+	27661255	K562	viability	GGCGCAGGACAGGGACTGAGAGG	MAPKAPK3	ENSG00000114738	0.10137163370996105	[875,811]	[720,726]	3	dCas9-KRAB	negative selection	5471083
50617217	50617240	3	-	27661255	K562	viability	GGCGGCAACGCACCTTGCTGAGG	MAPKAPK3	ENSG00000114738	0.16355896620369142	[942,1063]	[917,876]	6	dCas9-KRAB	negative selection	5492276
50617238	50617261	3	-	27661255	K562	viability	GGGCCCAGCGAGGGCGTACCTGG	MAPKAPK3	ENSG00000114738	0.00315748809890698	[666,585]	[580,435]	0	dCas9-KRAB	negative selection	5492277
50617328	50617351	3	-	27661255	K562	viability	GGTACAAGCGAGCACCGCCCGGG	MAPKAPK3	ENSG00000114738	0.09086113160340412	[695,632]	[636,505]	3	dCas9-KRAB	negative selection	5492278
50617608	50617631	3	-	27661255	K562	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	0.06468262049556461	[328,347]	[322,247]	2	dCas9-KRAB	negative selection	5492279
50646814	50646837	3	-	27260156	BXPC3	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.07966064459446638	[416]	[370,418,394,694]	1	hSpCas9	negative selection	5554423
50646759	50646782	3	-	27260156	BXPC3	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.4215684189520004	[393]	[535,574,426,678]	8	hSpCas9	negative selection	5554424
50640404	50640427	3	-	27260156	BXPC3	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.25589978537961	[556]	[690,568,791,739]	5	hSpCas9	negative selection	5554425
50611623	50611646	3	+	27260156	BXPC3	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.1498521908312772	[762]	[674,653,593,987]	-3	hSpCas9	negative selection	5600166
50611632	50611655	3	-	27260156	BXPC3	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	-0.07279360543827884	[724]	[644,731,678,843]	-2	hSpCas9	negative selection	5600167
50640381	50640404	3	-	27260156	BXPC3	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.238373003068643	[301]	[262,325,462,462]	5	hSpCas9	negative selection	5618681
50641750	50641773	3	+	27260156	BXPC3	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.5745762209627041	[261]	[310,410,430,497]	9	hSpCas9	negative selection	5618682
50641752	50641775	3	-	27260156	BXPC3	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.10570427719530051	[906]	[961,916,1083,1139]	2	hSpCas9	negative selection	5618683
50646814	50646837	3	-	27260156	A673	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.26473154011688255	[416]	[571,568,628,633]	6	hSpCas9	negative selection	5675674
50646759	50646782	3	-	27260156	A673	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.5598573111781487	[393]	[743,713,632,702]	9	hSpCas9	negative selection	5675675
50640404	50640427	3	-	27260156	A673	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.12403341757625119	[556]	[906,722,635,665]	3	hSpCas9	negative selection	5675676
50611623	50611646	3	+	27260156	A673	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.15965241288767218	[762]	[899,706,919,759]	-4	hSpCas9	negative selection	5721417
50611632	50611655	3	-	27260156	A673	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	-0.009715783293487879	[724]	[1110,791,744,838]	0	hSpCas9	negative selection	5721418
50640381	50640404	3	-	27260156	A673	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.43592092957123946	[301]	[594,426,464,487]	8	hSpCas9	negative selection	5739932
50641750	50641773	3	+	27260156	A673	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.4420970200899129	[261]	[507,366,412,431]	8	hSpCas9	negative selection	5739933
50641752	50641775	3	-	27260156	A673	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.06431400620119199	[906]	[1268,976,1133,1194]	1	hSpCas9	negative selection	5739934
50646814	50646837	3	-	27260156	A375	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.05534803372362265	[416]	[438,622,569,416]	0	hSpCas9	negative selection	5796925
50646759	50646782	3	-	27260156	A375	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.6173067306681725	[393]	[621,1039,666,555]	8	hSpCas9	negative selection	5796926
50640404	50640427	3	-	27260156	A375	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	-0.1747357492850658	[556]	[334,631,634,692]	-3	hSpCas9	negative selection	5796927
50611623	50611646	3	+	27260156	A375	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.5374122010379079	[762]	[526,885,464,612]	-6	hSpCas9	negative selection	5842668
50611632	50611655	3	-	27260156	A375	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.08359288676548615	[724]	[1134,904,590,950]	1	hSpCas9	negative selection	5842669
50640381	50640404	3	-	27260156	A375	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.7203092911064188	[301]	[664,499,762,404]	9	hSpCas9	negative selection	5861183
50641750	50641773	3	+	27260156	A375	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.4726438331808364	[261]	[353,478,529,349]	7	hSpCas9	negative selection	5861184
50641752	50641775	3	-	27260156	A375	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.029195707130093118	[906]	[830,1361,804,1328]	0	hSpCas9	negative selection	5861185
50646814	50646837	3	-	27260156	COLO741	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.2172273394340282	[416]	[554,475,805]	4	hSpCas9	negative selection	5918176
50646759	50646782	3	-	27260156	COLO741	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.44570979895302587	[393]	[712,621,719]	8	hSpCas9	negative selection	5918177
50640404	50640427	3	-	27260156	COLO741	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.17122839921690147	[556]	[859,687,854]	3	hSpCas9	negative selection	5918178
50611623	50611646	3	+	27260156	COLO741	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.2309101197967181	[762]	[1141,654,726]	-5	hSpCas9	negative selection	5963919
50611632	50611655	3	-	27260156	COLO741	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	-0.016009010916095967	[724]	[1051,1004,715]	0	hSpCas9	negative selection	5963920
50640381	50640404	3	-	27260156	COLO741	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.2953064240411758	[301]	[647,438,355]	6	hSpCas9	negative selection	5982434
50641750	50641773	3	+	27260156	COLO741	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.5223264188770216	[261]	[552,464,432]	9	hSpCas9	negative selection	5982435
50641752	50641775	3	-	27260156	COLO741	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.06391386457696879	[906]	[1128,1275,1218]	1	hSpCas9	negative selection	5982436
50646814	50646837	3	-	27260156	CAL120	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	-0.12609534091793462	[416]	[373,450,583]	-2	hSpCas9	negative selection	6039427
50646759	50646782	3	-	27260156	CAL120	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.8015355187412325	[393]	[1497,580,585]	9	hSpCas9	negative selection	6039428
50640404	50640427	3	-	27260156	CAL120	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	-0.18190849554567606	[556]	[682,570,589]	-3	hSpCas9	negative selection	6039429
50611623	50611646	3	+	27260156	CAL120	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.8130000071942368	[762]	[724,391,531]	-8	hSpCas9	negative selection	6085170
50611632	50611655	3	-	27260156	CAL120	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.20277993970875285	[724]	[1713,674,830]	3	hSpCas9	negative selection	6085171
50640381	50640404	3	-	27260156	CAL120	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.9906260048506867	[301]	[652,612,955]	9	hSpCas9	negative selection	6103685
50641750	50641773	3	+	27260156	CAL120	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.6171690091587299	[261]	[728,389,416]	8	hSpCas9	negative selection	6103686
50641752	50641775	3	-	27260156	CAL120	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.11254935680628542	[906]	[1441,1446,811]	1	hSpCas9	negative selection	6103687
50646814	50646837	3	-	27260156	CADOES1	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.1062055180972511	[416]	[429,429,413,394]	1	hSpCas9	negative selection	6160678
50646759	50646782	3	-	27260156	CADOES1	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.21661958243927223	[393]	[466,467,373,392]	3	hSpCas9	negative selection	6160679
50640404	50640427	3	-	27260156	CADOES1	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.0771302325187862	[556]	[525,710,361,588]	1	hSpCas9	negative selection	6160680
50611623	50611646	3	+	27260156	CADOES1	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.5202177301233148	[762]	[469,466,348,700]	-7	hSpCas9	negative selection	6206421
50611632	50611655	3	-	27260156	CADOES1	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	-0.0067483613037740975	[724]	[513,760,640,772]	0	hSpCas9	negative selection	6206422
50640381	50640404	3	-	27260156	CADOES1	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.44915160657358244	[301]	[403,458,388,277]	7	hSpCas9	negative selection	6224936
50641750	50641773	3	+	27260156	CADOES1	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.37679044857559885	[261]	[336,195,320,414]	6	hSpCas9	negative selection	6224937
50641752	50641775	3	-	27260156	CADOES1	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.2838956605598948	[906]	[980,956,1168,999]	5	hSpCas9	negative selection	6224938
50646814	50646837	3	-	27260156	EWS502	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.002312937279785099	[416]	[367,511,437,456]	0	hSpCas9	negative selection	6281929
50646759	50646782	3	-	27260156	EWS502	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.3943330775346441	[393]	[423,619,562,600]	7	hSpCas9	negative selection	6281930
50640404	50640427	3	-	27260156	EWS502	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.00013597981503496448	[556]	[419,604,768,585]	0	hSpCas9	negative selection	6281931
50611623	50611646	3	+	27260156	EWS502	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.23598856967055315	[762]	[639,673,750,683]	-4	hSpCas9	negative selection	6327672
50611632	50611655	3	-	27260156	EWS502	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.019825594901668797	[724]	[722,720,896,780]	0	hSpCas9	negative selection	6327673
50640381	50640404	3	-	27260156	EWS502	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.8082130626140525	[301]	[643,502,536,544]	9	hSpCas9	negative selection	6346187
50641750	50641773	3	+	27260156	EWS502	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.08580376971041015	[261]	[283,233,379,282]	1	hSpCas9	negative selection	6346188
50641752	50641775	3	-	27260156	EWS502	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.2716613330374802	[906]	[1043,1127,933,1569]	5	hSpCas9	negative selection	6346189
50646814	50646837	3	-	27260156	EW8	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.15132081002364473	[416]	[490,274,269,493]	2	hSpCas9	negative selection	6403180
50646759	50646782	3	-	27260156	EW8	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	1.0174245375916517	[393]	[440,1406,341,426]	9	hSpCas9	negative selection	6403181
50640404	50640427	3	-	27260156	EW8	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.31286480544407747	[556]	[712,597,444,521]	6	hSpCas9	negative selection	6403182
50611623	50611646	3	+	27260156	EW8	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.3718825974517638	[762]	[569,367,492,485]	-6	hSpCas9	negative selection	6448923
50611632	50611655	3	-	27260156	EW8	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.05960800892228646	[724]	[612,674,462,721]	1	hSpCas9	negative selection	6448924
50640381	50640404	3	-	27260156	EW8	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.6619515180675751	[301]	[639,290,276,385]	9	hSpCas9	negative selection	6467438
50641750	50641773	3	+	27260156	EW8	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.890798683351068	[261]	[444,579,320,246]	9	hSpCas9	negative selection	6467439
50641752	50641775	3	-	27260156	EW8	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.1210232853201505	[906]	[900,755,782,768]	2	hSpCas9	negative selection	6467440
50646814	50646837	3	-	27260156	CORL105	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.6043489318919988	[416]	[916,696,711,644]	9	hSpCas9	negative selection	6524431
50646759	50646782	3	-	27260156	CORL105	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.48853790237452543	[393]	[605,577,766,655]	8	hSpCas9	negative selection	6524432
50640404	50640427	3	-	27260156	CORL105	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.25890721363748304	[556]	[844,583,684,996]	5	hSpCas9	negative selection	6524433
50611623	50611646	3	+	27260156	CORL105	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.12156260277136888	[762]	[789,749,1265,548]	-2	hSpCas9	negative selection	6570174
50611632	50611655	3	-	27260156	CORL105	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.1470100565280269	[724]	[959,724,983,1100]	2	hSpCas9	negative selection	6570175
50640381	50640404	3	-	27260156	CORL105	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.5656044913100491	[301]	[494,577,398,598]	8	hSpCas9	negative selection	6588689
50641750	50641773	3	+	27260156	CORL105	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.6737050379081577	[261]	[557,383,506,514]	9	hSpCas9	negative selection	6588690
50641752	50641775	3	-	27260156	CORL105	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.41981441042170187	[906]	[1556,1349,1447,1336]	7	hSpCas9	negative selection	6588691
50646814	50646837	3	-	27260156	HS294T	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	-0.023473041131845618	[416]	[129,187,152,165]	0	hSpCas9	negative selection	6645682
50646759	50646782	3	-	27260156	HS294T	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.8008920916602591	[393]	[288,265,194,316]	8	hSpCas9	negative selection	6645683
50640404	50640427	3	-	27260156	HS294T	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.28816043168273675	[556]	[235,170,380,269]	4	hSpCas9	negative selection	6645684
50611623	50611646	3	+	27260156	HS294T	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	0.23118303150797404	[762]	[247,259,274,666]	3	hSpCas9	negative selection	6691425
50611632	50611655	3	-	27260156	HS294T	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.5583868514616586	[724]	[544,300,450,329]	7	hSpCas9	negative selection	6691426
50640381	50640404	3	-	27260156	HS294T	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.6838484420336314	[301]	[112,173,179,310]	8	hSpCas9	negative selection	6709940
50641750	50641773	3	+	27260156	HS294T	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-0.004714901681297623	[261]	[78,67,152,107]	0	hSpCas9	negative selection	6709941
50641752	50641775	3	-	27260156	HS294T	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	-0.10113646716353031	[906]	[289,306,246,494]	-1	hSpCas9	negative selection	6709942
50646814	50646837	3	-	27260156	HCC44	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	-0.1885628026117107	[416]	[453,324,607,317]	-3	hSpCas9	negative selection	6766933
50646759	50646782	3	-	27260156	HCC44	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.2083946359911753	[393]	[685,396,647,383]	3	hSpCas9	negative selection	6766934
50640404	50640427	3	-	27260156	HCC44	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.20498944158273286	[556]	[732,845,550,721]	3	hSpCas9	negative selection	6766935
50611623	50611646	3	+	27260156	HCC44	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.19490878487539143	[762]	[869,762,800,597]	-3	hSpCas9	negative selection	6812676
50611632	50611655	3	-	27260156	HCC44	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.3502244000458674	[724]	[1382,883,1187,803]	6	hSpCas9	negative selection	6812677
50640381	50640404	3	-	27260156	HCC44	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.37220155950578127	[301]	[471,341,436,526]	6	hSpCas9	negative selection	6831191
50641750	50641773	3	+	27260156	HCC44	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.6947216041011357	[261]	[411,445,604,471]	9	hSpCas9	negative selection	6831192
50641752	50641775	3	-	27260156	HCC44	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.3513626824334961	[906]	[1441,1454,1293,1030]	6	hSpCas9	negative selection	6831193
50646814	50646837	3	-	27260156	G402	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.3563158810520932	[416]	[870,624,503,633]	4	hSpCas9	negative selection	6888184
50646759	50646782	3	-	27260156	G402	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.3070863028599423	[393]	[839,332,881,353]	4	hSpCas9	negative selection	6888185
50640404	50640427	3	-	27260156	G402	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.18013628184718428	[556]	[747,1011,768,568]	2	hSpCas9	negative selection	6888186
50611623	50611646	3	+	27260156	G402	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.6556411157418539	[762]	[395,608,831,501]	-7	hSpCas9	negative selection	6933927
50611632	50611655	3	-	27260156	G402	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.31299893945072654	[724]	[809,778,724,1973]	4	hSpCas9	negative selection	6933928
50640381	50640404	3	-	27260156	G402	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.42184107793085956	[301]	[377,603,710,279]	5	hSpCas9	negative selection	6952442
50641750	50641773	3	+	27260156	G402	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	1.209683042601509	[261]	[646,419,928,917]	9	hSpCas9	negative selection	6952443
50641752	50641775	3	-	27260156	G402	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.09160460533073156	[906]	[1263,1405,1292,793]	1	hSpCas9	negative selection	6952444
50646814	50646837	3	-	27260156	L33	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.24178600101441092	[416]	[545,167,345,464]	5	hSpCas9	negative selection	7009435
50646759	50646782	3	-	27260156	L33	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.49756684132697276	[393]	[605,196,391,513]	8	hSpCas9	negative selection	7009436
50640404	50640427	3	-	27260156	L33	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.2477029143104647	[556]	[581,302,464,586]	5	hSpCas9	negative selection	7009437
50611623	50611646	3	+	27260156	L33	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.5574499566121734	[762]	[467,194,326,609]	-8	hSpCas9	negative selection	7055178
50611632	50611655	3	-	27260156	L33	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	-0.08462860606110856	[724]	[560,289,515,648]	-2	hSpCas9	negative selection	7055179
50640381	50640404	3	-	27260156	L33	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.2508117530453838	[301]	[360,168,200,343]	5	hSpCas9	negative selection	7073693
50641750	50641773	3	+	27260156	L33	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.3553224327031392	[261]	[312,128,221,359]	7	hSpCas9	negative selection	7073694
50641752	50641775	3	-	27260156	L33	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.1360250733491566	[906]	[1050,328,618,1144]	3	hSpCas9	negative selection	7073695
50646814	50646837	3	-	27260156	K562	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.3610937576277262	[416]	[618,400,401,483]	4	hSpCas9	negative selection	7130686
50646759	50646782	3	-	27260156	K562	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.6624434291883488	[393]	[617,869,142,596]	8	hSpCas9	negative selection	7130687
50640404	50640427	3	-	27260156	K562	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.191377535379939	[556]	[826,453,576,428]	2	hSpCas9	negative selection	7130688
50611623	50611646	3	+	27260156	K562	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	0.28102340994664365	[762]	[652,864,1465,347]	3	hSpCas9	negative selection	7176429
50611632	50611655	3	-	27260156	K562	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.26043857934579706	[724]	[839,584,753,882]	3	hSpCas9	negative selection	7176430
50640381	50640404	3	-	27260156	K562	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.7370668632342903	[301]	[622,546,285,358]	8	hSpCas9	negative selection	7194944
50641750	50641773	3	+	27260156	K562	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.08591061346044249	[261]	[196,303,312,178]	1	hSpCas9	negative selection	7194945
50641752	50641775	3	-	27260156	K562	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.2900840637889095	[906]	[1238,1283,555,899]	3	hSpCas9	negative selection	7194946
50646814	50646837	3	-	27260156	HT29	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.26168998117350284	[416]	[638,684,606,515]	5	hSpCas9	negative selection	7251937
50646759	50646782	3	-	27260156	HT29	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.5055329400562971	[393]	[529,850,782,567]	8	hSpCas9	negative selection	7251938
50640404	50640427	3	-	27260156	HT29	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	-0.027105193084743268	[556]	[820,746,670,458]	0	hSpCas9	negative selection	7251939
50611623	50611646	3	+	27260156	HT29	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.08076394276589283	[762]	[773,1149,938,678]	-2	hSpCas9	negative selection	7297680
50611632	50611655	3	-	27260156	HT29	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.03405174062983474	[724]	[1085,1101,784,687]	0	hSpCas9	negative selection	7297681
50640381	50640404	3	-	27260156	HT29	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.6805297259287448	[301]	[686,495,434,714]	9	hSpCas9	negative selection	7316195
50641750	50641773	3	+	27260156	HT29	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.6549198617736941	[261]	[595,513,420,481]	9	hSpCas9	negative selection	7316196
50641752	50641775	3	-	27260156	HT29	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.3004125711923673	[906]	[1490,1446,1428,1103]	6	hSpCas9	negative selection	7316197
50646814	50646837	3	-	27260156	MHHES1	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.1251501135162084	[416]	[543,525,566,425]	2	hSpCas9	negative selection	7373188
50646759	50646782	3	-	27260156	MHHES1	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.49452346108485795	[393]	[714,582,860,390]	8	hSpCas9	negative selection	7373189
50640404	50640427	3	-	27260156	MHHES1	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.05109214402242368	[556]	[726,592,749,543]	1	hSpCas9	negative selection	7373190
50611623	50611646	3	+	27260156	MHHES1	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.15695186720924403	[762]	[1124,740,714,570]	-3	hSpCas9	negative selection	7418931
50611632	50611655	3	-	27260156	MHHES1	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.3377236469179806	[724]	[1157,1101,1097,818]	6	hSpCas9	negative selection	7418932
50640381	50640404	3	-	27260156	MHHES1	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.35368022439646934	[301]	[508,550,455,271]	6	hSpCas9	negative selection	7437446
50641750	50641773	3	+	27260156	MHHES1	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.20326231496207314	[261]	[352,376,432,221]	4	hSpCas9	negative selection	7437447
50641752	50641775	3	-	27260156	MHHES1	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.33515343272091846	[906]	[1759,1385,1259,881]	6	hSpCas9	negative selection	7437448
50646814	50646837	3	-	27260156	MEWO	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.31484742582933545	[416]	[596,353,526]	6	hSpCas9	negative selection	7494439
50646759	50646782	3	-	27260156	MEWO	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.35390783532991055	[393]	[616,355,468]	7	hSpCas9	negative selection	7494440
50640404	50640427	3	-	27260156	MEWO	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.22973768615103674	[556]	[695,714,437]	5	hSpCas9	negative selection	7494441
50611623	50611646	3	+	27260156	MEWO	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.16137884870089747	[762]	[733,487,711]	-4	hSpCas9	negative selection	7540182
50611632	50611655	3	-	27260156	MEWO	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.0416656963942571	[724]	[664,470,952]	0	hSpCas9	negative selection	7540183
50640381	50640404	3	-	27260156	MEWO	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.5228421022482495	[301]	[534,355,351]	9	hSpCas9	negative selection	7558697
50641750	50641773	3	+	27260156	MEWO	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.141393107808911	[261]	[263,224,320]	3	hSpCas9	negative selection	7558698
50641752	50641775	3	-	27260156	MEWO	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.3647905643918752	[906]	[1322,972,1026]	7	hSpCas9	negative selection	7558699
50646814	50646837	3	-	27260156	LNCAPCLONEFGC	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.2625277069485566	[416]	[462,423,439,484]	4	hSpCas9	negative selection	7615690
50646759	50646782	3	-	27260156	LNCAPCLONEFGC	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.5651837607872741	[393]	[536,457,511,606]	8	hSpCas9	negative selection	7615691
50640404	50640427	3	-	27260156	LNCAPCLONEFGC	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.1690596252721619	[556]	[636,580,455,575]	2	hSpCas9	negative selection	7615692
50611623	50611646	3	+	27260156	LNCAPCLONEFGC	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.5855884041841861	[762]	[585,468,345,420]	-7	hSpCas9	negative selection	7661433
50611632	50611655	3	-	27260156	LNCAPCLONEFGC	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.04869543213236094	[724]	[593,653,732,746]	0	hSpCas9	negative selection	7661434
50640381	50640404	3	-	27260156	LNCAPCLONEFGC	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.681210174370803	[301]	[372,468,420,487]	9	hSpCas9	negative selection	7679948
50641750	50641773	3	+	27260156	LNCAPCLONEFGC	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.2891568516030053	[261]	[219,345,306,286]	4	hSpCas9	negative selection	7679949
50641752	50641775	3	-	27260156	LNCAPCLONEFGC	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.15144755549991862	[906]	[912,888,1059,810]	2	hSpCas9	negative selection	7679950
50646814	50646837	3	-	27260156	PANC0327	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.26483249581477564	[416]	[610,443,459,278]	4	hSpCas9	negative selection	7736941
50646759	50646782	3	-	27260156	PANC0327	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.32313666846748934	[393]	[728,369,411,272]	5	hSpCas9	negative selection	7736942
50640404	50640427	3	-	27260156	PANC0327	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.3174011705510992	[556]	[681,770,368,628]	5	hSpCas9	negative selection	7736943
50611623	50611646	3	+	27260156	PANC0327	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.04730917786337008	[762]	[842,717,679,389]	0	hSpCas9	negative selection	7782684
50611632	50611655	3	-	27260156	PANC0327	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	-0.23570031081979786	[724]	[872,548,414,376]	-4	hSpCas9	negative selection	7782685
50640381	50640404	3	-	27260156	PANC0327	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.7839932638126356	[301]	[630,563,272,379]	9	hSpCas9	negative selection	7801199
50641750	50641773	3	+	27260156	PANC0327	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.4781808905437725	[261]	[256,284,248,504]	7	hSpCas9	negative selection	7801200
50641752	50641775	3	-	27260156	PANC0327	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.3461939495616797	[906]	[1512,826,944,876]	5	hSpCas9	negative selection	7801201
50646814	50646837	3	-	27260156	NCIH2009	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.8262744090361933	[416]	[858,919,1285]	9	hSpCas9	negative selection	7858192
50646759	50646782	3	-	27260156	NCIH2009	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.49729564735994586	[393]	[810,804,719]	7	hSpCas9	negative selection	7858193
50640404	50640427	3	-	27260156	NCIH2009	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.22564880166115542	[556]	[1154,953,666]	3	hSpCas9	negative selection	7858194
50611623	50611646	3	+	27260156	NCIH2009	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.3350842332961677	[762]	[1114,743,729]	-4	hSpCas9	negative selection	7903935
50611632	50611655	3	-	27260156	NCIH2009	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.2932993081417745	[724]	[1213,1041,1463]	4	hSpCas9	negative selection	7903936
50640381	50640404	3	-	27260156	NCIH2009	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.38927212496698077	[301]	[444,589,599]	5	hSpCas9	negative selection	7922450
50641750	50641773	3	+	27260156	NCIH2009	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.8292240367702399	[261]	[666,557,729]	9	hSpCas9	negative selection	7922451
50641752	50641775	3	-	27260156	NCIH2009	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.5035440463840053	[906]	[2152,1575,1731]	7	hSpCas9	negative selection	7922452
50646814	50646837	3	-	27260156	NCIH1373	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.511150590987801	[416]	[731,334,645,266]	5	hSpCas9	negative selection	7979443
50646759	50646782	3	-	27260156	NCIH1373	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	1.3145668086463989	[393]	[2146,702,783,251]	9	hSpCas9	negative selection	7979444
50640404	50640427	3	-	27260156	NCIH1373	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.17423075381663483	[556]	[881,534,608,221]	1	hSpCas9	negative selection	7979445
50611623	50611646	3	+	27260156	NCIH1373	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.39365594166815043	[762]	[333,849,612,193]	-4	hSpCas9	negative selection	8025186
50611632	50611655	3	-	27260156	NCIH1373	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.381350411154626	[724]	[1336,498,1507,255]	4	hSpCas9	negative selection	8025187
50640381	50640404	3	-	27260156	NCIH1373	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.2589734911741464	[301]	[310,569,239,123]	2	hSpCas9	negative selection	8043701
50641750	50641773	3	+	27260156	NCIH1373	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-0.03969670018367455	[261]	[341,257,267,74]	0	hSpCas9	negative selection	8043702
50641752	50641775	3	-	27260156	NCIH1373	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.49491181053266886	[906]	[2180,1148,1182,356]	5	hSpCas9	negative selection	8043703
50646814	50646837	3	-	27260156	PATU8902	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.2841688222898452	[416]	[821,681,199,1322]	3	hSpCas9	negative selection	8100694
50646759	50646782	3	-	27260156	PATU8902	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.10766603138963426	[393]	[608,565,491,735]	1	hSpCas9	negative selection	8100695
50640404	50640427	3	-	27260156	PATU8902	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.25203378775493024	[556]	[347,1197,940,1242]	2	hSpCas9	negative selection	8100696
50611623	50611646	3	+	27260156	PATU8902	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.3165950859177362	[762]	[695,997,861,849]	-3	hSpCas9	negative selection	8146437
50611632	50611655	3	-	27260156	PATU8902	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.024366081705782028	[724]	[981,1847,484,914]	0	hSpCas9	negative selection	8146438
50640381	50640404	3	-	27260156	PATU8902	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	1.106674848150164	[301]	[918,910,914,862]	9	hSpCas9	negative selection	8164952
50641750	50641773	3	+	27260156	PATU8902	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	1.31414020981962	[261]	[903,808,847,1098]	9	hSpCas9	negative selection	8164953
50641752	50641775	3	-	27260156	PATU8902	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.2655533838739246	[906]	[1586,1111,1523,1877]	2	hSpCas9	negative selection	8164954
50646814	50646837	3	-	27260156	PANC1	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	-0.10127701599534372	[416]	[396,245,442,240]	-2	hSpCas9	negative selection	8221945
50646759	50646782	3	-	27260156	PANC1	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.5767980491179474	[393]	[459,397,828,333]	8	hSpCas9	negative selection	8221946
50640404	50640427	3	-	27260156	PANC1	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	-0.11190850771180472	[556]	[396,453,519,402]	-2	hSpCas9	negative selection	8221947
50611623	50611646	3	+	27260156	PANC1	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.7738563916864056	[762]	[409,486,322,334]	-8	hSpCas9	negative selection	8267688
50611632	50611655	3	-	27260156	PANC1	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.10157583680402105	[724]	[832,607,738,494]	1	hSpCas9	negative selection	8267689
50640381	50640404	3	-	27260156	PANC1	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.38544269173003287	[301]	[282,392,346,338]	6	hSpCas9	negative selection	8286203
50641750	50641773	3	+	27260156	PANC1	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.2935254924734556	[261]	[222,469,230,223]	5	hSpCas9	negative selection	8286204
50641752	50641775	3	-	27260156	PANC1	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.21642717662521238	[906]	[859,1095,978,738]	3	hSpCas9	negative selection	8286205
50646814	50646837	3	-	27260156	PANC0813	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.8163556842197145	[416]	[874,945,809,820]	9	hSpCas9	negative selection	8343196
50646759	50646782	3	-	27260156	PANC0813	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.6454846771020866	[393]	[819,809,812,474]	8	hSpCas9	negative selection	8343197
50640404	50640427	3	-	27260156	PANC0813	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.28388473590762975	[556]	[914,829,753,701]	4	hSpCas9	negative selection	8343198
50611623	50611646	3	+	27260156	PANC0813	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.29679479726093594	[762]	[1068,629,559,690]	-5	hSpCas9	negative selection	8388939
50611632	50611655	3	-	27260156	PANC0813	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.028679698646667084	[724]	[982,897,899,711]	0	hSpCas9	negative selection	8388940
50640381	50640404	3	-	27260156	PANC0813	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.270097201431955	[301]	[419,485,385,417]	4	hSpCas9	negative selection	8407454
50641750	50641773	3	+	27260156	PANC0813	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.43684014157353274	[261]	[527,433,358,357]	7	hSpCas9	negative selection	8407455
50641752	50641775	3	-	27260156	PANC0813	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.31972504526026513	[906]	[1428,1412,1428,1069]	5	hSpCas9	negative selection	8407456
50646814	50646837	3	-	27260156	RDES	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.3126519495707417	[416]	[508,491,736,671]	5	hSpCas9	negative selection	8464447
50646759	50646782	3	-	27260156	RDES	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.28012619726035526	[393]	[491,613,532,548]	4	hSpCas9	negative selection	8464448
50640404	50640427	3	-	27260156	RDES	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.2205409222067249	[556]	[616,860,699,807]	3	hSpCas9	negative selection	8464449
50611623	50611646	3	+	27260156	RDES	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.3732564410609194	[762]	[640,565,672,852]	-6	hSpCas9	negative selection	8510190
50611632	50611655	3	-	27260156	RDES	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.27685291300492143	[724]	[854,1009,1153,1031]	4	hSpCas9	negative selection	8510191
50640381	50640404	3	-	27260156	RDES	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.9166147085443394	[301]	[506,499,818,862]	9	hSpCas9	negative selection	8528705
50641750	50641773	3	+	27260156	RDES	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.5428370003171928	[261]	[372,422,482,487]	8	hSpCas9	negative selection	8528706
50641752	50641775	3	-	27260156	RDES	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.15902929372982166	[906]	[1083,1023,1195,1381]	2	hSpCas9	negative selection	8528707
50646814	50646837	3	-	27260156	PC3	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.31352616147505535	[416]	[342,429,743,672]	6	hSpCas9	negative selection	8585698
50646759	50646782	3	-	27260156	PC3	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.37494420419528574	[393]	[352,368,854,622]	7	hSpCas9	negative selection	8585699
50640404	50640427	3	-	27260156	PC3	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.08025762671560338	[556]	[356,586,1170,501]	1	hSpCas9	negative selection	8585700
50611623	50611646	3	+	27260156	PC3	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.40189006123467014	[762]	[314,499,1109,658]	-7	hSpCas9	negative selection	8631441
50611632	50611655	3	-	27260156	PC3	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.029879677566644114	[724]	[426,472,1375,1022]	0	hSpCas9	negative selection	8631442
50640381	50640404	3	-	27260156	PC3	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.24948256656974377	[301]	[255,388,471,361]	5	hSpCas9	negative selection	8649956
50641750	50641773	3	+	27260156	PC3	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.19570179697085455	[261]	[189,264,521,327]	4	hSpCas9	negative selection	8649957
50641752	50641775	3	-	27260156	PC3	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.25926118647445007	[906]	[680,932,1884,1227]	5	hSpCas9	negative selection	8649958
50646814	50646837	3	-	27260156	PATU8988T	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.48099727865990594	[416]	[291,860,487,643]	7	hSpCas9	negative selection	8706949
50646759	50646782	3	-	27260156	PATU8988T	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.5701028547565388	[393]	[583,815,328,557]	8	hSpCas9	negative selection	8706950
50640404	50640427	3	-	27260156	PATU8988T	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.15506620681676997	[556]	[707,432,698,534]	2	hSpCas9	negative selection	8706951
50611623	50611646	3	+	27260156	PATU8988T	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	0.05830024082957885	[762]	[595,1059,638,807]	1	hSpCas9	negative selection	8752692
50611632	50611655	3	-	27260156	PATU8988T	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	-0.2003493559056015	[724]	[468,714,556,716]	-3	hSpCas9	negative selection	8752693
50640381	50640404	3	-	27260156	PATU8988T	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.4338162282282199	[301]	[302,400,508,359]	7	hSpCas9	negative selection	8771207
50641750	50641773	3	+	27260156	PATU8988T	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.4527472396342029	[261]	[433,543,230,183]	7	hSpCas9	negative selection	8771208
50641752	50641775	3	-	27260156	PATU8988T	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.27743439239416845	[906]	[1058,1283,938,982]	5	hSpCas9	negative selection	8771209
50646814	50646837	3	-	27260156	T47D	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.1994120613431301	[416]	[562,482,579,612]	4	hSpCas9	negative selection	8828200
50646759	50646782	3	-	27260156	T47D	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.4764059457291896	[393]	[619,580,674,683]	8	hSpCas9	negative selection	8828201
50640404	50640427	3	-	27260156	T47D	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.1320191118724635	[556]	[724,627,728,770]	3	hSpCas9	negative selection	8828202
50611623	50611646	3	+	27260156	T47D	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.2532422185686215	[762]	[806,740,698,736]	-5	hSpCas9	negative selection	8873943
50611632	50611655	3	-	27260156	T47D	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.008222980593724283	[724]	[861,757,876,909]	0	hSpCas9	negative selection	8873944
50640381	50640404	3	-	27260156	T47D	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.30772072125856653	[301]	[435,363,384,567]	6	hSpCas9	negative selection	8892458
50641750	50641773	3	+	27260156	T47D	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.5313231890821916	[261]	[431,409,429,496]	9	hSpCas9	negative selection	8892459
50641752	50641775	3	-	27260156	T47D	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.252684369709647	[906]	[1177,1202,1306,1353]	5	hSpCas9	negative selection	8892460
50646814	50646837	3	-	27260156	SU8686	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.2622665643074589	[416]	[417,413,497,702]	4	hSpCas9	negative selection	8949451
50646759	50646782	3	-	27260156	SU8686	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.44927452633317355	[393]	[467,520,523,642]	7	hSpCas9	negative selection	8949452
50640404	50640427	3	-	27260156	SU8686	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.2891334935246699	[556]	[593,637,634,871]	5	hSpCas9	negative selection	8949453
50611623	50611646	3	+	27260156	SU8686	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.07520714530348738	[762]	[763,581,699,854]	-1	hSpCas9	negative selection	8995194
50611632	50611655	3	-	27260156	SU8686	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.07120584632853144	[724]	[721,688,816,809]	1	hSpCas9	negative selection	8995195
50640381	50640404	3	-	27260156	SU8686	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.6068213518696728	[301]	[486,419,350,580]	8	hSpCas9	negative selection	9013709
50641750	50641773	3	+	27260156	SU8686	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.567680918971905	[261]	[276,332,393,584]	8	hSpCas9	negative selection	9013710
50641752	50641775	3	-	27260156	SU8686	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	-0.012308265721553413	[906]	[931,761,905,987]	0	hSpCas9	negative selection	9013711
50646814	50646837	3	-	27260156	SKES1	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	-0.07603191711293283	[416]	[468,423,349,350]	-2	hSpCas9	negative selection	9070702
50646759	50646782	3	-	27260156	SKES1	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.2122443074118997	[393]	[490,465,397,466]	4	hSpCas9	negative selection	9070703
50640404	50640427	3	-	27260156	SKES1	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.05627787895966252	[556]	[716,624,505,492]	1	hSpCas9	negative selection	9070704
50611623	50611646	3	+	27260156	SKES1	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.4714088300701842	[762]	[475,623,726,379]	-8	hSpCas9	negative selection	9116445
50611632	50611655	3	-	27260156	SKES1	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	-0.018383454909810526	[724]	[908,816,611,568]	0	hSpCas9	negative selection	9116446
50640381	50640404	3	-	27260156	SKES1	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.09625079099948075	[301]	[319,352,422,204]	2	hSpCas9	negative selection	9134960
50641750	50641773	3	+	27260156	SKES1	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.7298661957566832	[261]	[622,361,378,388]	9	hSpCas9	negative selection	9134961
50641752	50641775	3	-	27260156	SKES1	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.05946189600915108	[906]	[1078,1059,836,832]	1	hSpCas9	negative selection	9134962
50646814	50646837	3	-	27260156	TOV112D	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.22060609495496328	[416]	[529,542,500,391]	4	hSpCas9	negative selection	9191953
50646759	50646782	3	-	27260156	TOV112D	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.6170595119628552	[393]	[545,641,304,921]	9	hSpCas9	negative selection	9191954
50640404	50640427	3	-	27260156	TOV112D	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	-0.15648115415679087	[556]	[404,791,441,427]	-3	hSpCas9	negative selection	9191955
50611623	50611646	3	+	27260156	TOV112D	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.15554442336036567	[762]	[589,803,788,583]	-3	hSpCas9	negative selection	9237696
50611632	50611655	3	-	27260156	TOV112D	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	-0.15496401097987383	[724]	[510,990,629,549]	-3	hSpCas9	negative selection	9237697
50640381	50640404	3	-	27260156	TOV112D	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.593254245421324	[301]	[292,766,507,322]	9	hSpCas9	negative selection	9256211
50641750	50641773	3	+	27260156	TOV112D	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.27431913651170414	[261]	[375,246,332,300]	5	hSpCas9	negative selection	9256212
50641752	50641775	3	-	27260156	TOV112D	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.1696607468379696	[906]	[1010,1198,1037,883]	3	hSpCas9	negative selection	9256213
50646814	50646837	3	-	27260156	TC71	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.06109201124402683	[416]	[392,430,467,581]	1	hSpCas9	negative selection	9313204
50646759	50646782	3	-	27260156	TC71	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.406275815955617	[393]	[636,495,480,629]	8	hSpCas9	negative selection	9313205
50640404	50640427	3	-	27260156	TC71	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.2004836012700219	[556]	[528,671,767,781]	5	hSpCas9	negative selection	9313206
50611623	50611646	3	+	27260156	TC71	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.21690762448616335	[762]	[632,781,653,751]	-5	hSpCas9	negative selection	9358947
50611632	50611655	3	-	27260156	TC71	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	-0.08355027564732154	[724]	[613,590,908,821]	-2	hSpCas9	negative selection	9358948
50640381	50640404	3	-	27260156	TC71	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.23466334574565179	[301]	[376,437,352,354]	6	hSpCas9	negative selection	9377462
50641750	50641773	3	+	27260156	TC71	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.2256628467555396	[261]	[444,250,260,357]	5	hSpCas9	negative selection	9377463
50641752	50641775	3	-	27260156	TC71	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	-0.04434402953204175	[906]	[831,908,945,1095]	-1	hSpCas9	negative selection	9377464
50646814	50646837	3	-	27260156	TC32	viability	GAGGGGCTCACGTTGATCCAGGG	MAPKAPK3	ENSG00000114738	0.052069875466555976	[416]	[418,252,587,430]	1	hSpCas9	negative selection	9434455
50646759	50646782	3	-	27260156	TC32	viability	CTGTGGGGTCTGTCTTCAACAGG	MAPKAPK3	ENSG00000114738	0.098982185157176	[393]	[371,214,558,525]	1	hSpCas9	negative selection	9434456
50640404	50640427	3	-	27260156	TC32	viability	CGCCAGAAGCCTGCCAGTGATGG	MAPKAPK3	ENSG00000114738	0.008119818363805043	[556]	[439,325,878,582]	0	hSpCas9	negative selection	9434457
50611623	50611646	3	+	27260156	TC32	viability	GCGCTTACCCCTGAACGCAGAGG	MAPKAPK3	ENSG00000114738	-0.21192262465187323	[762]	[711,421,779,614]	-4	hSpCas9	negative selection	9480198
50611632	50611655	3	-	27260156	TC32	viability	GGACATGGTCCTCTGCGTTCAGG	MAPKAPK3	ENSG00000114738	0.10835745493952975	[724]	[679,531,1016,801]	2	hSpCas9	negative selection	9480199
50640381	50640404	3	-	27260156	TC32	viability	TCTACCTCCTGCCGGGCCTTGGG	MAPKAPK3	ENSG00000114738	0.8029201516898501	[301]	[493,503,541,406]	9	hSpCas9	negative selection	9498713
50641750	50641773	3	+	27260156	TC32	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.38669525670481664	[261]	[336,252,448,271]	6	hSpCas9	negative selection	9498714
50641752	50641775	3	-	27260156	TC32	viability	TACCTCTCTCAGTGAAAGCCTGG	MAPKAPK3	ENSG00000114738	0.18367854894906843	[906]	[688,864,1255,1137]	3	hSpCas9	negative selection	9498715
50617688	50617711	3	+	27869803	HPAFII	viability after 27 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.5739079025284929	[582]	[272,149,NaN]	-4	hSpCas9	negative selection	9585536
50617743	50617766	3	+	27869803	HPAFII	viability after 27 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-1.0166397719828564	[112]	[12,42,NaN]	-6	hSpCas9	negative selection	9585537
50641712	50641735	3	+	27869803	HPAFII	viability after 27 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	1.1137705101808	[195]	[324,137,NaN]	8	hSpCas9	negative selection	9585538
50642290	50642313	3	-	27869803	HPAFII	viability after 27 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.4942352481827671	[458]	[388,298,NaN]	4	hSpCas9	negative selection	9585539
50646156	50646179	3	-	27869803	HPAFII	viability after 27 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.6735792649961359	[494]	[401,425,NaN]	5	hSpCas9	negative selection	9585540
50647920	50647943	3	+	27869803	HPAFII	viability after 27 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-1.7761583620264823	[198]	[23,35,NaN]	-8	hSpCas9	negative selection	9585541
50617688	50617711	3	+	27869803	HPAFII	viability after 15 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.34526222445290533	[582]	[618,414,NaN]	-4	hSpCas9	negative selection	9667985
50617743	50617766	3	+	27869803	HPAFII	viability after 15 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.23755286683607546	[112]	[128,151,NaN]	2	hSpCas9	negative selection	9667986
50641712	50641735	3	+	27869803	HPAFII	viability after 15 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.6407395048967428	[195]	[423,268,NaN]	7	hSpCas9	negative selection	9667987
50642290	50642313	3	-	27869803	HPAFII	viability after 15 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.5788987183178399	[458]	[890,640,NaN]	6	hSpCas9	negative selection	9667988
50646156	50646179	3	-	27869803	HPAFII	viability after 15 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.4079837371027004	[494]	[1007,517,NaN]	5	hSpCas9	negative selection	9667989
50647920	50647943	3	+	27869803	HPAFII	viability after 15 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-1.3586967781424477	[198]	[38,110,NaN]	-8	hSpCas9	negative selection	9667990
50617688	50617711	3	+	27869803	ASPC1	viability after 36 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	0.8652226430047509	[1103]	[491,1259,398]	8	hSpCas9	negative selection	9750434
50617743	50617766	3	+	27869803	ASPC1	viability after 36 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.6840775528185599	[256]	[24,95,44]	-6	hSpCas9	negative selection	9750435
50641712	50641735	3	+	27869803	ASPC1	viability after 36 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	-0.19055313795099407	[623]	[83,298,177]	-2	hSpCas9	negative selection	9750436
50642290	50642313	3	-	27869803	ASPC1	viability after 36 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.41996370427591345	[1283]	[638,553,601]	4	hSpCas9	negative selection	9750437
50646156	50646179	3	-	27869803	ASPC1	viability after 36 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.13457189837087125	[1184]	[454,590,339]	1	hSpCas9	negative selection	9750438
50647920	50647943	3	+	27869803	ASPC1	viability after 36 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-0.20682801816474494	[381]	[280,38,58]	-2	hSpCas9	negative selection	9750439
50617688	50617711	3	+	27869803	PATU8988S	viability after 35 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.41737214222911984	[1009]	[343,264,NaN]	-4	hSpCas9	negative selection	9832883
50617743	50617766	3	+	27869803	PATU8988S	viability after 35 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.49610673066995736	[248]	[115,166,NaN]	5	hSpCas9	negative selection	9832884
50641712	50641735	3	+	27869803	PATU8988S	viability after 35 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.40928676651142	[528]	[257,307,NaN]	4	hSpCas9	negative selection	9832885
50642290	50642313	3	-	27869803	PATU8988S	viability after 35 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.9298532868915445	[823]	[514,749,NaN]	8	hSpCas9	negative selection	9832886
50646156	50646179	3	-	27869803	PATU8988S	viability after 35 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.165457820002464	[1015]	[423,493,NaN]	2	hSpCas9	negative selection	9832887
50647920	50647943	3	+	27869803	PATU8988S	viability after 35 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	0.9224731330161323	[324]	[287,207,NaN]	8	hSpCas9	negative selection	9832888
50617688	50617711	3	+	27869803	PATU8988S	viability after 31 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.0007989663604457409	[1009]	[343,476,NaN]	0	hSpCas9	negative selection	9915332
50617743	50617766	3	+	27869803	PATU8988S	viability after 31 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	0.7417214551098483	[248]	[92,258,NaN]	8	hSpCas9	negative selection	9915333
50641712	50641735	3	+	27869803	PATU8988S	viability after 31 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.6014042694311491	[528]	[268,384,NaN]	7	hSpCas9	negative selection	9915334
50642290	50642313	3	-	27869803	PATU8988S	viability after 31 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	1.0929479284969585	[823]	[600,827,NaN]	9	hSpCas9	negative selection	9915335
50646156	50646179	3	-	27869803	PATU8988S	viability after 31 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.2409197230244705	[1015]	[443,522,NaN]	3	hSpCas9	negative selection	9915336
50647920	50647943	3	+	27869803	PATU8988S	viability after 31 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	0.639281076550696	[324]	[229,165,NaN]	7	hSpCas9	negative selection	9915337
50617688	50617711	3	+	27869803	HPAFII	viability after 35 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.29671069656412785	[582]	[323,145,NaN]	-2	hSpCas9	negative selection	9997781
50617743	50617766	3	+	27869803	HPAFII	viability after 35 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.1857059482624026	[112]	[54,44,NaN]	-1	hSpCas9	negative selection	9997782
50641712	50641735	3	+	27869803	HPAFII	viability after 35 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	0.9953522778872566	[195]	[289,93,NaN]	6	hSpCas9	negative selection	9997783
50642290	50642313	3	-	27869803	HPAFII	viability after 35 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.5060949831234801	[458]	[345,311,NaN]	3	hSpCas9	negative selection	9997784
50646156	50646179	3	-	27869803	HPAFII	viability after 35 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.7745872097280493	[494]	[510,335,NaN]	5	hSpCas9	negative selection	9997785
50647920	50647943	3	+	27869803	HPAFII	viability after 35 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-2.2791531619130447	[198]	[0,42,NaN]	-8	hSpCas9	negative selection	9997786
50617688	50617711	3	+	27869803	HPAFII	viability after 31 days	CGACTACCAGTTGTCCAAGCAGG	MAPKAPK3	ENSG00000114738	-0.09649200530536595	[582]	[406,195,NaN]	0	hSpCas9	negative selection	10080230
50617743	50617766	3	+	27869803	HPAFII	viability after 31 days	GAGTGCTTCCATCGGCGCACTGG	MAPKAPK3	ENSG00000114738	-0.7221641040444791	[112]	[25,51,NaN]	-5	hSpCas9	negative selection	10080231
50641712	50641735	3	+	27869803	HPAFII	viability after 31 days	AAGGTGGTGAGTTGTTCAGCAGG	MAPKAPK3	ENSG00000114738	1.2225606966904432	[195]	[327,178,NaN]	8	hSpCas9	negative selection	10080232
50642290	50642313	3	-	27869803	HPAFII	viability after 31 days	TGTTATGGCTGTGCAGAAACTGG	MAPKAPK3	ENSG00000114738	0.5211484655696798	[458]	[261,486,NaN]	4	hSpCas9	negative selection	10080233
50646156	50646179	3	-	27869803	HPAFII	viability after 31 days	TGGCCCGTGTTGGAGTAGAAGGG	MAPKAPK3	ENSG00000114738	0.6890963332045343	[494]	[411,486,NaN]	5	hSpCas9	negative selection	10080234
50647920	50647943	3	+	27869803	HPAFII	viability after 31 days	TATGCGGGTAGACTACGACCAGG	MAPKAPK3	ENSG00000114738	-1.6537966112632474	[198]	[12,59,NaN]	-7	hSpCas9	negative selection	10080235
50617608	50617631	3	-	28162770	P31FUJ	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	-0.5372428725728999	[409]	[331]	-4	hSpCas9	negative selection	10189192
50640370	50640393	3	+	28162770	P31FUJ	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.1216598546213763	[455]	[582]	1	hSpCas9	negative selection	10189193
50642317	50642340	3	-	28162770	P31FUJ	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.6374299206152918	[185]	[339]	7	hSpCas9	negative selection	10189194
50646753	50646776	3	-	28162770	P31FUJ	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	-2.2328022044143783	[11]	[2]	-8	hSpCas9	negative selection	10189195
50646791	50646814	3	-	28162770	P31FUJ	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	0.6100968345008925	[251]	[451]	7	hSpCas9	negative selection	10189196
50617565	50617588	3	+	28162770	P31FUJ	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	0.17485576449886775	[48]	[64]	1	hSpCas9	negative selection	10189197
50617694	50617717	3	+	28162770	P31FUJ	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	0.9557755039298256	[110]	[252]	9	hSpCas9	negative selection	10189198
50617721	50617744	3	+	28162770	P31FUJ	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	0.06078126477902204	[256]	[314]	0	hSpCas9	negative selection	10189199
50641750	50641773	3	+	28162770	P31FUJ	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-0.16671301395660615	[255]	[267]	-2	hSpCas9	negative selection	10189200
50646810	50646833	3	-	28162770	P31FUJ	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	0.47769117839063613	[43]	[71]	5	hSpCas9	negative selection	10189201
50617608	50617631	3	-	28162770	TF1	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	NaN	[NaN]	[431]	1	hSpCas9	negative selection	10358558
50640370	50640393	3	+	28162770	TF1	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	NaN	[NaN]	[388]	1	hSpCas9	negative selection	10358559
50642317	50642340	3	-	28162770	TF1	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	NaN	[NaN]	[303]	1	hSpCas9	negative selection	10358560
50646753	50646776	3	-	28162770	TF1	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10358561
50646791	50646814	3	-	28162770	TF1	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10358562
50617565	50617588	3	+	28162770	TF1	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10358563
50617694	50617717	3	+	28162770	TF1	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10358564
50617721	50617744	3	+	28162770	TF1	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10358565
50641750	50641773	3	+	28162770	TF1	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	NaN	[NaN]	[382]	1	hSpCas9	negative selection	10358566
50646810	50646833	3	-	28162770	TF1	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10358567
50617608	50617631	3	-	28162770	SKM1	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	0.33606314821024585	[94]	[211]	3	hSpCas9	negative selection	10527924
50640370	50640393	3	+	28162770	SKM1	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.2054790384001014	[103]	[211]	2	hSpCas9	negative selection	10527925
50642317	50642340	3	-	28162770	SKM1	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.8589298612298726	[62]	[201]	7	hSpCas9	negative selection	10527926
50646753	50646776	3	-	28162770	SKM1	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	-2.0443941193584534	[6]	[2]	-8	hSpCas9	negative selection	10527927
50646791	50646814	3	-	28162770	SKM1	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	-0.04439411935845339	[83]	[143]	0	hSpCas9	negative selection	10527928
50617565	50617588	3	+	28162770	SKM1	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	-0.08503610385579918	[20]	[34]	0	hSpCas9	negative selection	10527929
50617694	50617717	3	+	28162770	SKM1	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	0.5436477742946748	[25]	[66]	5	hSpCas9	negative selection	10527930
50617721	50617744	3	+	28162770	SKM1	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	-0.29932347555519195	[70]	[101]	-3	hSpCas9	negative selection	10527931
50641750	50641773	3	+	28162770	SKM1	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.20994119448074883	[66]	[136]	2	hSpCas9	negative selection	10527932
50646810	50646833	3	-	28162770	SKM1	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	0.5930358012568382	[8]	[23]	6	hSpCas9	negative selection	10527933
50617608	50617631	3	-	28162770	SKM1	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	0.33606314821024585	[94]	[211]	3	hSpCas9	negative selection	10697290
50640370	50640393	3	+	28162770	SKM1	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.2054790384001014	[103]	[211]	2	hSpCas9	negative selection	10697291
50642317	50642340	3	-	28162770	SKM1	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.8589298612298726	[62]	[201]	7	hSpCas9	negative selection	10697292
50646753	50646776	3	-	28162770	SKM1	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	-2.0443941193584534	[6]	[2]	-8	hSpCas9	negative selection	10697293
50646791	50646814	3	-	28162770	SKM1	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	-0.04439411935845339	[83]	[143]	0	hSpCas9	negative selection	10697294
50617565	50617588	3	+	28162770	SKM1	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	-0.08503610385579918	[20]	[34]	0	hSpCas9	negative selection	10697295
50617694	50617717	3	+	28162770	SKM1	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	0.5436477742946748	[25]	[66]	5	hSpCas9	negative selection	10697296
50617721	50617744	3	+	28162770	SKM1	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	-0.29932347555519195	[70]	[101]	-3	hSpCas9	negative selection	10697297
50641750	50641773	3	+	28162770	SKM1	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.20994119448074883	[66]	[136]	2	hSpCas9	negative selection	10697298
50646810	50646833	3	-	28162770	SKM1	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	0.5930358012568382	[8]	[23]	6	hSpCas9	negative selection	10697299
50617608	50617631	3	-	28162770	PL21	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	0.11160293988766279	[335]	[157]	1	hSpCas9	negative selection	10866656
50640370	50640393	3	+	28162770	PL21	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.26467986668403054	[305]	[159]	2	hSpCas9	negative selection	10866657
50642317	50642340	3	-	28162770	PL21	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	-0.16909419517639884	[247]	[95]	-1	hSpCas9	negative selection	10866658
50646753	50646776	3	-	28162770	PL21	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	1.2001396144893204	[14]	[14]	8	hSpCas9	negative selection	10866659
50646791	50646814	3	-	28162770	PL21	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	-0.2120551350206984	[337]	[126]	-1	hSpCas9	negative selection	10866660
50617565	50617588	3	+	28162770	PL21	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	0.9437998612295346	[42]	[35]	7	hSpCas9	negative selection	10866661
50617694	50617717	3	+	28162770	PL21	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	1.1550517249607823	[64]	[62]	8	hSpCas9	negative selection	10866662
50617721	50617744	3	+	28162770	PL21	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	0.6475985914605414	[131]	[89]	5	hSpCas9	negative selection	10866663
50641750	50641773	3	+	28162770	PL21	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-0.38482288623183614	[209]	[69]	-3	hSpCas9	negative selection	10866664
50646810	50646833	3	-	28162770	PL21	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	-2.2148978847895244	[31]	[2]	-8	hSpCas9	negative selection	10866665
50617608	50617631	3	-	28162770	P31FUJ	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	-0.5372428725728999	[409]	[331]	-4	hSpCas9	negative selection	11036022
50640370	50640393	3	+	28162770	P31FUJ	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.1216598546213763	[455]	[582]	1	hSpCas9	negative selection	11036023
50642317	50642340	3	-	28162770	P31FUJ	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.6374299206152918	[185]	[339]	7	hSpCas9	negative selection	11036024
50646753	50646776	3	-	28162770	P31FUJ	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	-2.2328022044143783	[11]	[2]	-8	hSpCas9	negative selection	11036025
50646791	50646814	3	-	28162770	P31FUJ	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	0.6100968345008925	[251]	[451]	7	hSpCas9	negative selection	11036026
50617565	50617588	3	+	28162770	P31FUJ	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	0.17485576449886775	[48]	[64]	1	hSpCas9	negative selection	11036027
50617694	50617717	3	+	28162770	P31FUJ	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	0.9557755039298256	[110]	[252]	9	hSpCas9	negative selection	11036028
50617721	50617744	3	+	28162770	P31FUJ	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	0.06078126477902204	[256]	[314]	0	hSpCas9	negative selection	11036029
50641750	50641773	3	+	28162770	P31FUJ	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-0.16671301395660615	[255]	[267]	-2	hSpCas9	negative selection	11036030
50646810	50646833	3	-	28162770	P31FUJ	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	0.47769117839063613	[43]	[71]	5	hSpCas9	negative selection	11036031
50617608	50617631	3	-	28162770	OCIAML5	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	-1.3995543661664902	[208]	[142]	-7	hSpCas9	negative selection	11205388
50640370	50640393	3	+	28162770	OCIAML5	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.1508391603114141	[247]	[496]	1	hSpCas9	negative selection	11205389
50642317	50642340	3	-	28162770	OCIAML5	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	-0.055599964949129055	[151]	[263]	0	hSpCas9	negative selection	11205390
50646753	50646776	3	-	28162770	OCIAML5	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	-1.7696044106720246	[16]	[8]	-7	hSpCas9	negative selection	11205391
50646791	50646814	3	-	28162770	OCIAML5	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	-0.39128348136357066	[193]	[266]	-3	hSpCas9	negative selection	11205392
50617565	50617588	3	+	28162770	OCIAML5	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	-0.11510097669779062	[29]	[49]	-1	hSpCas9	negative selection	11205393
50617694	50617717	3	+	28162770	OCIAML5	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	0.7853633497512946	[62]	[195]	7	hSpCas9	negative selection	11205394
50617721	50617744	3	+	28162770	OCIAML5	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	-0.28616240595852555	[126]	[187]	-2	hSpCas9	negative selection	11205395
50641750	50641773	3	+	28162770	OCIAML5	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.9704747550082831	[107]	[381]	8	hSpCas9	negative selection	11205396
50646810	50646833	3	-	28162770	OCIAML5	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	-2.4370290715851533	[11]	[3]	-8	hSpCas9	negative selection	11205397
50617608	50617631	3	-	28162770	EOL1	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	-0.21984213776464012	[671]	[303]	-2	hSpCas9	negative selection	11374754
50640370	50640393	3	+	28162770	EOL1	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.9137947152736601	[403]	[400]	7	hSpCas9	negative selection	11374755
50642317	50642340	3	-	28162770	EOL1	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	1.1438140919202628	[395]	[460]	8	hSpCas9	negative selection	11374756
50646753	50646776	3	-	28162770	EOL1	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	-0.3555601476222008	[33]	[13]	-3	hSpCas9	negative selection	11374757
50646791	50646814	3	-	28162770	EOL1	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	0.26633628881873983	[504]	[319]	2	hSpCas9	negative selection	11374758
50617565	50617588	3	+	28162770	EOL1	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	1.3822296082578718	[74]	[102]	9	hSpCas9	negative selection	11374759
50617694	50617717	3	+	28162770	EOL1	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	-1.031058109071012	[127]	[32]	-6	hSpCas9	negative selection	11374760
50617721	50617744	3	+	28162770	EOL1	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	-1.3670066742733091	[234]	[47]	-7	hSpCas9	negative selection	11374761
50641750	50641773	3	+	28162770	EOL1	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-0.665467956876907	[285]	[94]	-5	hSpCas9	negative selection	11374762
50646810	50646833	3	-	28162770	EOL1	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	-0.5900254012592239	[59]	[20]	-4	hSpCas9	negative selection	11374763
50617608	50617631	3	-	28162770	MOLM13	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	0.19551711113144876	[464]	[384]	1	hSpCas9	negative selection	11544120
50640370	50640393	3	+	28162770	MOLM13	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	-0.6298474201512181	[457]	[213]	-4	hSpCas9	negative selection	11544121
50642317	50642340	3	-	28162770	MOLM13	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	-0.1573207091824324	[417]	[270]	-1	hSpCas9	negative selection	11544122
50646753	50646776	3	-	28162770	MOLM13	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	-4.0556725745124345	[22]	[0]	-9	hSpCas9	negative selection	11544123
50646791	50646814	3	-	28162770	MOLM13	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	1.193966659568049	[398]	[659]	8	hSpCas9	negative selection	11544124
50617565	50617588	3	+	28162770	MOLM13	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	1.583366598964515	[65]	[142]	9	hSpCas9	negative selection	11544125
50617694	50617717	3	+	28162770	MOLM13	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	0.04313672743252339	[148]	[110]	0	hSpCas9	negative selection	11544126
50617721	50617744	3	+	28162770	MOLM13	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	-0.3525611981247085	[248]	[140]	-2	hSpCas9	negative selection	11544127
50641750	50641773	3	+	28162770	MOLM13	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-1.3168426315523547	[347]	[100]	-6	hSpCas9	negative selection	11544128
50646810	50646833	3	-	28162770	MOLM13	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	-1.1170731191765775	[47]	[15]	-5	hSpCas9	negative selection	11544129
50617608	50617631	3	-	28162770	HEL	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	1.4491855418523998	[453]	[793]	9	hSpCas9	negative selection	11713486
50640370	50640393	3	+	28162770	HEL	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.5038026417564322	[402]	[365]	4	hSpCas9	negative selection	11713487
50642317	50642340	3	-	28162770	HEL	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.05540931673528454	[304]	[202]	0	hSpCas9	negative selection	11713488
50646753	50646776	3	-	28162770	HEL	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	0.6427388320003571	[15]	[15]	5	hSpCas9	negative selection	11713489
50646791	50646814	3	-	28162770	HEL	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	0.6220990659413207	[351]	[346]	5	hSpCas9	negative selection	11713490
50617565	50617588	3	+	28162770	HEL	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	-0.13747996011973318	[78]	[45]	-1	hSpCas9	negative selection	11713491
50617694	50617717	3	+	28162770	HEL	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	0.5147312196242857	[105]	[96]	4	hSpCas9	negative selection	11713492
50617721	50617744	3	+	28162770	HEL	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	0.16321260626979966	[243]	[174]	1	hSpCas9	negative selection	11713493
50641750	50641773	3	+	28162770	HEL	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-0.487657805255318	[323]	[147]	-3	hSpCas9	negative selection	11713494
50646810	50646833	3	-	28162770	HEL	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	1.057776331279201	[38]	[51]	8	hSpCas9	negative selection	11713495
50617608	50617631	3	-	28162770	MV411	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	0.23775499738543593	[298]	[296]	2	hSpCas9	negative selection	11882852
50640370	50640393	3	+	28162770	MV411	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	-0.11586097852444743	[282]	[219]	-1	hSpCas9	negative selection	11882853
50642317	50642340	3	-	28162770	MV411	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.26451106414171677	[251]	[254]	2	hSpCas9	negative selection	11882854
50646753	50646776	3	-	28162770	MV411	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	1.6166713604484944	[11]	[30]	9	hSpCas9	negative selection	11882855
50646791	50646814	3	-	28162770	MV411	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	0.27030165913451254	[312]	[317]	2	hSpCas9	negative selection	11882856
50617565	50617588	3	+	28162770	MV411	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	-0.2220477325184449	[35]	[25]	-2	hSpCas9	negative selection	11882857
50617694	50617717	3	+	28162770	MV411	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	1.0752565754000951	[119]	[212]	8	hSpCas9	negative selection	11882858
50617721	50617744	3	+	28162770	MV411	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	0.07211929057024444	[200]	[177]	0	hSpCas9	negative selection	11882859
50641750	50641773	3	+	28162770	MV411	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.7201905479179065	[146]	[203]	6	hSpCas9	negative selection	11882860
50646810	50646833	3	-	28162770	MV411	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	-2.453002167358317	[64]	[9]	-8	hSpCas9	negative selection	11882861
50617608	50617631	3	-	28162770	MONOMAC1	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	1.3109032334377573	[217]	[619]	9	hSpCas9	negative selection	12052218
50640370	50640393	3	+	28162770	MONOMAC1	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	-0.033256585838150055	[182]	[204]	0	hSpCas9	negative selection	12052219
50642317	50642340	3	-	28162770	MONOMAC1	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	1.1958778413211502	[114]	[301]	9	hSpCas9	negative selection	12052220
50646753	50646776	3	-	28162770	MONOMAC1	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	-0.5189649419469164	[4]	[3]	-4	hSpCas9	negative selection	12052221
50646791	50646814	3	-	28162770	MONOMAC1	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	1.7183988576819735	[201]	[761]	9	hSpCas9	negative selection	12052222
50617565	50617588	3	+	28162770	MONOMAC1	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	-0.8250680696725958	[33]	[21]	-6	hSpCas9	negative selection	12052223
50617694	50617717	3	+	28162770	MONOMAC1	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	-0.3247923942579265	[58]	[53]	-3	hSpCas9	negative selection	12052224
50617721	50617744	3	+	28162770	MONOMAC1	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	0.6466599220617708	[111]	[200]	6	hSpCas9	negative selection	12052225
50641750	50641773	3	+	28162770	MONOMAC1	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	-0.2069523159246364	[145]	[144]	-2	hSpCas9	negative selection	12052226
50646810	50646833	3	-	28162770	MONOMAC1	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	-1.6120743463383973	[23]	[8]	-8	hSpCas9	negative selection	12052227
50617608	50617631	3	-	28162770	OCIAML2	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	0.13423223291669983	[71]	[437]	1	hSpCas9	negative selection	12221584
50640370	50640393	3	+	28162770	OCIAML2	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.08600395242050063	[59]	[352]	0	hSpCas9	negative selection	12221585
50642317	50642340	3	-	28162770	OCIAML2	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.9269625395772734	[38]	[410]	8	hSpCas9	negative selection	12221586
50646753	50646776	3	-	28162770	OCIAML2	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	-3.7925579201295236	[4]	[1]	-9	hSpCas9	negative selection	12221587
50646791	50646814	3	-	28162770	OCIAML2	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	0.1814468713375319	[55]	[351]	1	hSpCas9	negative selection	12221588
50617565	50617588	3	+	28162770	OCIAML2	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	0.16495874854896275	[13]	[86]	1	hSpCas9	negative selection	12221589
50617694	50617717	3	+	28162770	OCIAML2	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	-0.09476292324399505	[20]	[108]	-1	hSpCas9	negative selection	12221590
50617721	50617744	3	+	28162770	OCIAML2	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	0.8584937710494053	[19]	[200]	8	hSpCas9	negative selection	12221591
50641750	50641773	3	+	28162770	OCIAML2	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.21684758610492916	[42]	[276]	2	hSpCas9	negative selection	12221592
50646810	50646833	3	-	28162770	OCIAML2	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	-3.3450989431583027	[10]	[5]	-9	hSpCas9	negative selection	12221593
50617608	50617631	3	-	28162770	OCIAML3	viability	GGTCCGCCGGGTGCAACTGGCGG	MAPKAPK3	ENSG00000114738	0.22268514631277714	[87]	[309]	2	hSpCas9	negative selection	12390950
50640370	50640393	3	+	28162770	OCIAML3	viability	TGTATGACAGCCCCAAGGCCCGG	MAPKAPK3	ENSG00000114738	0.025306365187769964	[82]	[254]	0	hSpCas9	negative selection	12390951
50642317	50642340	3	-	28162770	OCIAML3	viability	GCCTCACCTTGACATCTCGGTGG	MAPKAPK3	ENSG00000114738	0.5062564831492659	[65]	[282]	5	hSpCas9	negative selection	12390952
50646753	50646776	3	-	28162770	OCIAML3	viability	GGTCTGTCTTCAACAGGAGGCGG	MAPKAPK3	ENSG00000114738	2.8654239783131334	[2]	[65]	9	hSpCas9	negative selection	12390953
50646791	50646814	3	-	28162770	OCIAML3	viability	GTGGTTCATGAACTGAGTGATGG	MAPKAPK3	ENSG00000114738	0.3414521074811262	[79]	[305]	3	hSpCas9	negative selection	12390954
50617565	50617588	3	+	28162770	OCIAML3	viability	CATGGATGGTGAAACAGCAGAGG	MAPKAPK3	ENSG00000114738	1.0093333897118477	[12]	[78]	8	hSpCas9	negative selection	12390955
50617694	50617717	3	+	28162770	OCIAML3	viability	CCAGTTGTCCAAGCAGGTGCTGG	MAPKAPK3	ENSG00000114738	-1.0090451396030071	[31]	[47]	-6	hSpCas9	negative selection	12390956
50617721	50617744	3	+	28162770	OCIAML3	viability	GGGTGTGAACGGCAAAGTGCTGG	MAPKAPK3	ENSG00000114738	0.26911055325544997	[57]	[210]	2	hSpCas9	negative selection	12390957
50641750	50641773	3	+	28162770	OCIAML3	viability	GACCAGGCTTTCACTGAGAGAGG	MAPKAPK3	ENSG00000114738	0.5726422290852882	[48]	[219]	5	hSpCas9	negative selection	12390958
50646810	50646833	3	-	28162770	OCIAML3	viability	GGCTCACGTTGATCCAGGGGTGG	MAPKAPK3	ENSG00000114738	-0.40136256238176715	[6]	[15]	-3	hSpCas9	negative selection	12390959