Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:57787
• Symbol:MARK4
• Description:microtubule affinity regulating kinase 4

DataSource: http://genomecrispr.dkfz.de/#!/results/MARK4

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
45090163	45090186	19	+	26472758	Jiyoye	viability	GGCCCTGATGGCTTCAGCCGTGG	MARK4	ENSG00000007047	0.9540027533402583	[114]	[167]	6	hSpCas9	negative selection	62736
45090237	45090260	19	-	26472758	Jiyoye	viability	CTTGAGCTATGGGACACTCCTGG	MARK4	ENSG00000007047	0.6872833006986088	[139]	[169]	5	hSpCas9	negative selection	62737
45090345	45090368	19	+	26472758	Jiyoye	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	-0.19715244408221377	[224]	[147]	-1	hSpCas9	negative selection	62738
45090297	45090320	19	-	26472758	Jiyoye	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.13956779698479246	[148]	[101]	-1	hSpCas9	negative selection	62739
45090312	45090335	19	-	26472758	Jiyoye	viability	CCATGGCCAGCAGGCTGCGGAGG	MARK4	ENSG00000007047	-1.889806356251258	[171]	[34]	-8	hSpCas9	negative selection	62740
45090329	45090352	19	-	26472758	Jiyoye	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.7153086250191215	[171]	[78]	-5	hSpCas9	negative selection	62741
45090398	45090421	19	-	26472758	Jiyoye	viability	GAAGTTGGCCACATCCAGGTCGG	MARK4	ENSG00000007047	-1.0185885243660289	[179]	[66]	-6	hSpCas9	negative selection	62742
45090263	45090286	19	+	26472758	Jiyoye	viability	CCCTGGAATCCCAGGAGCAGCGG	MARK4	ENSG00000007047	0.11989342942540224	[143]	[117]	0	hSpCas9	negative selection	62743
45090124	45090147	19	-	26472758	Jiyoye	viability	ACAGGCACGGGAATGTTCACTGG	MARK4	ENSG00000007047	-0.45789503840801815	[152]	[83]	-3	hSpCas9	negative selection	62744
45090210	45090233	19	-	26472758	Jiyoye	viability	CAGGAACCTCTGGCCTCAAGGGG	MARK4	ENSG00000007047	0.01326117379278366	[112]	[85]	0	hSpCas9	negative selection	62745
45264712	45264735	19	+	26472758	Jiyoye	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	-0.40334681963041374	[455]	[259]	-3	hSpCas9	negative selection	96669
45263145	45263168	19	+	26472758	Jiyoye	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.9573970507899828	[102]	[39]	-6	hSpCas9	negative selection	96670
45271587	45271610	19	-	26472758	Jiyoye	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-0.05029738409336687	[91]	[66]	0	hSpCas9	negative selection	96671
45271681	45271704	19	-	26472758	Jiyoye	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	-0.10463400687540525	[297]	[208]	0	hSpCas9	negative selection	96672
45278566	45278589	19	+	26472758	Jiyoye	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	0.9617642331835109	[63]	[93]	6	hSpCas9	negative selection	96673
45287621	45287644	19	+	26472758	Jiyoye	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	0.3140659771143919	[15]	[14]	2	hSpCas9	negative selection	96674
45297933	45297956	19	+	26472758	Jiyoye	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	-0.41594685641004725	[22]	[12]	-3	hSpCas9	negative selection	96675
45251611	45251634	19	-	26472758	Jiyoye	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-0.0739513082307427	[200]	[143]	0	hSpCas9	negative selection	96676
45259117	45259140	19	+	26472758	Jiyoye	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	-2.1889276768204833	[259]	[42]	-8	hSpCas9	negative selection	96677
45259168	45259191	19	+	26472758	Jiyoye	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	0.38251332727160436	[58]	[57]	3	hSpCas9	negative selection	96678
45090163	45090186	19	+	26472758	KBM7	viability	GGCCCTGATGGCTTCAGCCGTGG	MARK4	ENSG00000007047	0.7500520658319647	[408,277]	[292,244]	7	hSpCas9	negative selection	253854
45090237	45090260	19	-	26472758	KBM7	viability	CTTGAGCTATGGGACACTCCTGG	MARK4	ENSG00000007047	0.4619711572714199	[992,876]	[648,564]	5	hSpCas9	negative selection	253855
45090345	45090368	19	+	26472758	KBM7	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	1.0254072413260849	[708,471]	[795,341]	9	hSpCas9	negative selection	253856
45090297	45090320	19	-	26472758	KBM7	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	0.09751602614003363	[1054,651]	[409,430]	0	hSpCas9	negative selection	253857
45090312	45090335	19	-	26472758	KBM7	viability	CCATGGCCAGCAGGCTGCGGAGG	MARK4	ENSG00000007047	-1.5363762950739104	[446,474]	[106,46]	-8	hSpCas9	negative selection	253858
45090329	45090352	19	-	26472758	KBM7	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	0.04888000437178833	[640,436]	[326,196]	0	hSpCas9	negative selection	253859
45090398	45090421	19	-	26472758	KBM7	viability	GAAGTTGGCCACATCCAGGTCGG	MARK4	ENSG00000007047	-1.9854549448978942	[873,627]	[85,89]	-8	hSpCas9	negative selection	253860
45090263	45090286	19	+	26472758	KBM7	viability	CCCTGGAATCCCAGGAGCAGCGG	MARK4	ENSG00000007047	0.2695980768887206	[414,343]	[202,223]	3	hSpCas9	negative selection	253861
45090124	45090147	19	-	26472758	KBM7	viability	ACAGGCACGGGAATGTTCACTGG	MARK4	ENSG00000007047	0.5001003485278744	[536,713]	[442,406]	5	hSpCas9	negative selection	253862
45090210	45090233	19	-	26472758	KBM7	viability	CAGGAACCTCTGGCCTCAAGGGG	MARK4	ENSG00000007047	0.8350275012305199	[348,378]	[315,300]	8	hSpCas9	negative selection	253863
45264712	45264735	19	+	26472758	KBM7	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.12311133511543715	[1347,1088]	[653,589]	1	hSpCas9	negative selection	287787
45263145	45263168	19	+	26472758	KBM7	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.2845259649609799	[221,178]	[49,100]	-3	hSpCas9	negative selection	287788
45271587	45271610	19	-	26472758	KBM7	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-1.8673317482134837	[347,202]	[39,29]	-8	hSpCas9	negative selection	287789
45271681	45271704	19	-	26472758	KBM7	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	0.27950644703978833	[1029,759]	[601,418]	3	hSpCas9	negative selection	287790
45278566	45278589	19	+	26472758	KBM7	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	0.027639240885117045	[346,161]	[173,67]	0	hSpCas9	negative selection	287791
45287621	45287644	19	+	26472758	KBM7	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-0.8215810128689758	[49,25]	[12,6]	-6	hSpCas9	negative selection	287792
45297933	45297956	19	+	26472758	KBM7	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	0.14976327434873227	[143,104]	[78,50]	1	hSpCas9	negative selection	287793
45251611	45251634	19	-	26472758	KBM7	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	0.2646391627652809	[795,535]	[341,395]	2	hSpCas9	negative selection	287794
45259117	45259140	19	+	26472758	KBM7	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	-0.006718844011372738	[631,694]	[208,406]	0	hSpCas9	negative selection	287795
45259168	45259191	19	+	26472758	KBM7	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	0.06474796047960624	[378,369]	[253,122]	0	hSpCas9	negative selection	287796
45090163	45090186	19	+	26472758	Raji	viability	GGCCCTGATGGCTTCAGCCGTGG	MARK4	ENSG00000007047	-0.5193991410421838	[209]	[33]	-4	hSpCas9	negative selection	444972
45090237	45090260	19	-	26472758	Raji	viability	CTTGAGCTATGGGACACTCCTGG	MARK4	ENSG00000007047	0.13186622057294284	[408]	[103]	1	hSpCas9	negative selection	444973
45090345	45090368	19	+	26472758	Raji	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.6345314009739808	[296]	[106]	6	hSpCas9	negative selection	444974
45090297	45090320	19	-	26472758	Raji	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	0.487046704550558	[288]	[93]	4	hSpCas9	negative selection	444975
45090312	45090335	19	-	26472758	Raji	viability	CCATGGCCAGCAGGCTGCGGAGG	MARK4	ENSG00000007047	-0.40568604686577114	[136]	[23]	-3	hSpCas9	negative selection	444976
45090329	45090352	19	-	26472758	Raji	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.7782384434812676	[302]	[40]	-5	hSpCas9	negative selection	444977
45090398	45090421	19	-	26472758	Raji	viability	GAAGTTGGCCACATCCAGGTCGG	MARK4	ENSG00000007047	-2.1585105245994347	[403]	[20]	-8	hSpCas9	negative selection	444978
45090263	45090286	19	+	26472758	Raji	viability	CCCTGGAATCCCAGGAGCAGCGG	MARK4	ENSG00000007047	0.11642867497660647	[317]	[79]	1	hSpCas9	negative selection	444979
45090124	45090147	19	-	26472758	Raji	viability	ACAGGCACGGGAATGTTCACTGG	MARK4	ENSG00000007047	-0.9946374015669095	[248]	[28]	-6	hSpCas9	negative selection	444980
45090210	45090233	19	-	26472758	Raji	viability	CAGGAACCTCTGGCCTCAAGGGG	MARK4	ENSG00000007047	0.07072506479475124	[278]	[67]	0	hSpCas9	negative selection	444981
45264712	45264735	19	+	26472758	Raji	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.059765515140859815	[615]	[148]	0	hSpCas9	negative selection	478905
45263145	45263168	19	+	26472758	Raji	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.6768877735709633	[185]	[26]	-5	hSpCas9	negative selection	478906
45271587	45271610	19	-	26472758	Raji	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-0.02777604790803634	[122]	[27]	0	hSpCas9	negative selection	478907
45271681	45271704	19	-	26472758	Raji	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	0.08184844326646212	[341]	[83]	0	hSpCas9	negative selection	478908
45278566	45278589	19	+	26472758	Raji	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	1.1421489535342761	[122]	[62]	8	hSpCas9	negative selection	478909
45287621	45287644	19	+	26472758	Raji	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-0.9282403743571219	[40]	[4]	-6	hSpCas9	negative selection	478910
45297933	45297956	19	+	26472758	Raji	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	-0.333189056012382	[75]	[13]	-3	hSpCas9	negative selection	478911
45251611	45251634	19	-	26472758	Raji	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	0.19271558917336165	[278]	[73]	1	hSpCas9	negative selection	478912
45259117	45259140	19	+	26472758	Raji	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	-1.1874508986314876	[421]	[42]	-7	hSpCas9	negative selection	478913
45259168	45259191	19	+	26472758	Raji	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	-1.5364726544011251	[274]	[21]	-8	hSpCas9	negative selection	478914
45090163	45090186	19	+	26472758	K562	viability	GGCCCTGATGGCTTCAGCCGTGG	MARK4	ENSG00000007047	0.3230591769060114	[356]	[376]	2	hSpCas9	negative selection	636090
45090237	45090260	19	-	26472758	K562	viability	CTTGAGCTATGGGACACTCCTGG	MARK4	ENSG00000007047	-0.37240268687141137	[640]	[417]	-2	hSpCas9	negative selection	636091
45090345	45090368	19	+	26472758	K562	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.4087540474131218	[430]	[482]	3	hSpCas9	negative selection	636092
45090297	45090320	19	-	26472758	K562	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-2.463209321444179	[502]	[76]	-8	hSpCas9	negative selection	636093
45090312	45090335	19	-	26472758	K562	viability	CCATGGCCAGCAGGCTGCGGAGG	MARK4	ENSG00000007047	-2.755581272333553	[463]	[57]	-8	hSpCas9	negative selection	636094
45090329	45090352	19	-	26472758	K562	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	0.05765021606072046	[419]	[368]	0	hSpCas9	negative selection	636095
45090398	45090421	19	-	26472758	K562	viability	GAAGTTGGCCACATCCAGGTCGG	MARK4	ENSG00000007047	-2.347961244617192	[584]	[96]	-8	hSpCas9	negative selection	636096
45090263	45090286	19	+	26472758	K562	viability	CCCTGGAATCCCAGGAGCAGCGG	MARK4	ENSG00000007047	0.12412449394873487	[474]	[436]	0	hSpCas9	negative selection	636097
45090124	45090147	19	-	26472758	K562	viability	ACAGGCACGGGAATGTTCACTGG	MARK4	ENSG00000007047	1.3317161317236814	[512]	[1089]	9	hSpCas9	negative selection	636098
45090210	45090233	19	-	26472758	K562	viability	CAGGAACCTCTGGCCTCAAGGGG	MARK4	ENSG00000007047	-0.5197126187406417	[410]	[241]	-3	hSpCas9	negative selection	636099
45264712	45264735	19	+	26472758	K562	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.3448546789631992	[1067]	[1144]	2	hSpCas9	negative selection	670023
45263145	45263168	19	+	26472758	K562	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.24441872766644684	[246]	[246]	1	hSpCas9	negative selection	670024
45271587	45271610	19	-	26472758	K562	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-2.097973469780631	[141]	[27]	-7	hSpCas9	negative selection	670025
45271681	45271704	19	-	26472758	K562	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	0.6324531250386832	[754]	[987]	5	hSpCas9	negative selection	670026
45278566	45278589	19	+	26472758	K562	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	-0.46927708717691197	[204]	[124]	-3	hSpCas9	negative selection	670027
45287621	45287644	19	+	26472758	K562	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-5.709777582720427	[61]	[0]	-9	hSpCas9	negative selection	670028
45297933	45297956	19	+	26472758	K562	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	0.33604920313201525	[121]	[129]	2	hSpCas9	negative selection	670029
45251611	45251634	19	-	26472758	K562	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-0.04320766634973899	[425]	[348]	0	hSpCas9	negative selection	670030
45259117	45259140	19	+	26472758	K562	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	-1.4194951144495311	[506]	[159]	-6	hSpCas9	negative selection	670031
45259168	45259191	19	+	26472758	K562	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	1.1335346215469893	[391]	[725]	8	hSpCas9	negative selection	670032
45251618	45251641	19	+	26627737	DLD1	viability	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.49061920155220157	[725]	[175,117,184]	-5	hSpCas9	negative selection	805434
45259004	45259027	19	+	26627737	DLD1	viability	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	-0.21989519447767938	[530]	[197,72,151]	-2	hSpCas9	negative selection	805435
45263315	45263338	19	-	26627737	DLD1	viability	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.2238032770467418	[484]	[172,190,168]	2	hSpCas9	negative selection	805436
45264724	45264747	19	-	26627737	DLD1	viability	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	0.1235349806870811	[428]	[84,156,189]	1	hSpCas9	negative selection	805437
45264865	45264888	19	+	26627737	DLD1	viability	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.784544775860589	[239]	[166,188,46]	7	hSpCas9	negative selection	805438
45271685	45271708	19	-	26627737	DLD1	viability	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	-0.24048776696868224	[1110]	[291,330,264]	-3	hSpCas9	negative selection	805439
45251618	45251641	19	+	26627737	GBM cells	viability after 5 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.06118530378456266	[335]	[203,171]	1	hSpCas9	negative selection	887749
45259004	45259027	19	+	26627737	GBM cells	viability after 5 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	-0.024464843511401935	[219]	[102,128]	0	hSpCas9	negative selection	887750
45263315	45263338	19	-	26627737	GBM cells	viability after 5 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.41553924584368807	[280]	[237,163]	6	hSpCas9	negative selection	887751
45264724	45264747	19	-	26627737	GBM cells	viability after 5 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.10108612511431436	[182]	[87,94]	-1	hSpCas9	negative selection	887752
45264865	45264888	19	+	26627737	GBM cells	viability after 5 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.6271092594241597	[98]	[89,73]	8	hSpCas9	negative selection	887753
45271685	45271708	19	-	26627737	GBM cells	viability after 5 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.12007164057049469	[500]	[256,326]	2	hSpCas9	negative selection	887754
45251618	45251641	19	+	26627737	GBM cells	viability after 13 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.37239437678524867	[335]	[147,134]	-4	hSpCas9	negative selection	970064
45259004	45259027	19	+	26627737	GBM cells	viability after 13 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.1519523509685525	[219]	[141,124]	2	hSpCas9	negative selection	970065
45263315	45263338	19	-	26627737	GBM cells	viability after 13 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.4312907023699808	[280]	[209,201]	5	hSpCas9	negative selection	970066
45264724	45264747	19	-	26627737	GBM cells	viability after 13 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.8344103425839576	[182]	[42,65]	-7	hSpCas9	negative selection	970067
45264865	45264888	19	+	26627737	GBM cells	viability after 13 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.3983040887229954	[98]	[72,68]	5	hSpCas9	negative selection	970068
45271685	45271708	19	-	26627737	GBM cells	viability after 13 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.24244117493938178	[500]	[368,282]	3	hSpCas9	negative selection	970069
45251618	45251641	19	+	26627737	GBM cells	viability after 21 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.31055916518587046	[335]	[130,161]	-3	hSpCas9	negative selection	1052379
45259004	45259027	19	+	26627737	GBM cells	viability after 21 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.273466428576154	[219]	[156,132]	3	hSpCas9	negative selection	1052380
45263315	45263338	19	-	26627737	GBM cells	viability after 21 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.2250483211012079	[280]	[179,176]	2	hSpCas9	negative selection	1052381
45264724	45264747	19	-	26627737	GBM cells	viability after 21 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.5179100102362558	[182]	[70,67]	-5	hSpCas9	negative selection	1052382
45264865	45264888	19	+	26627737	GBM cells	viability after 21 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.508683544898184	[98]	[75,76]	5	hSpCas9	negative selection	1052383
45271685	45271708	19	-	26627737	GBM cells	viability after 21 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.23639710713859197	[500]	[328,312]	2	hSpCas9	negative selection	1052384
45251618	45251641	19	+	26627737	RPE1	viability after 9 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.043474399869904534	[939]	[340,213]	0	hSpCas9	negative selection	1134694
45259004	45259027	19	+	26627737	RPE1	viability after 9 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	-0.17715337029495823	[962]	[122,451]	-1	hSpCas9	negative selection	1134695
45263315	45263338	19	-	26627737	RPE1	viability after 9 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	1.4018026101926035	[741]	[670,539]	7	hSpCas9	negative selection	1134696
45264724	45264747	19	-	26627737	RPE1	viability after 9 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.5829381723056566	[410]	[36,148]	-4	hSpCas9	negative selection	1134697
45264865	45264888	19	+	26627737	RPE1	viability after 9 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	-0.13576677542291873	[703]	[159,252]	-1	hSpCas9	negative selection	1134698
45271685	45271708	19	-	26627737	RPE1	viability after 9 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.627703413877021	[1111]	[395,720]	4	hSpCas9	negative selection	1134699
45251618	45251641	19	+	26627737	RPE1	viability after 12 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.13348543163612253	[939]	[277,275]	0	hSpCas9	negative selection	1217009
45259004	45259027	19	+	26627737	RPE1	viability after 12 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	-0.35931548716983447	[962]	[173,230]	-2	hSpCas9	negative selection	1217010
45263315	45263338	19	-	26627737	RPE1	viability after 12 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	1.4493592916689666	[741]	[693,385]	7	hSpCas9	negative selection	1217011
45264724	45264747	19	-	26627737	RPE1	viability after 12 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.9619698785666362	[410]	[45,67]	-6	hSpCas9	negative selection	1217012
45264865	45264888	19	+	26627737	RPE1	viability after 12 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.08053598281056537	[703]	[182,217]	0	hSpCas9	negative selection	1217013
45271685	45271708	19	-	26627737	RPE1	viability after 12 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.48837022599317814	[1111]	[422,414]	3	hSpCas9	negative selection	1217014
45251618	45251641	19	+	26627737	RPE1	viability after 15 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.1258109892998679	[939]	[344,145]	-1	hSpCas9	negative selection	1299324
45259004	45259027	19	+	26627737	RPE1	viability after 15 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	-0.6345204903688417	[962]	[204,146]	-4	hSpCas9	negative selection	1299325
45263315	45263338	19	-	26627737	RPE1	viability after 15 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	1.8231162969945875	[741]	[899,590]	8	hSpCas9	negative selection	1299326
45264724	45264747	19	-	26627737	RPE1	viability after 15 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.07180796001982126	[410]	[103,116]	0	hSpCas9	negative selection	1299327
45264865	45264888	19	+	26627737	RPE1	viability after 15 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	-0.2538416437392621	[703]	[137,194]	-1	hSpCas9	negative selection	1299328
45271685	45271708	19	-	26627737	RPE1	viability after 15 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	-0.29178357348375916	[1111]	[230,281]	-2	hSpCas9	negative selection	1299329
45251618	45251641	19	+	26627737	RPE1	viability after 18 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-1.3894050654687187	[939]	[91,101]	-7	hSpCas9	negative selection	1381639
45259004	45259027	19	+	26627737	RPE1	viability after 18 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	-0.48609822938413677	[962]	[113,261]	-3	hSpCas9	negative selection	1381640
45263315	45263338	19	-	26627737	RPE1	viability after 18 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	1.4916632946274944	[741]	[711,403]	7	hSpCas9	negative selection	1381641
45264724	45264747	19	-	26627737	RPE1	viability after 18 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.02602046658395918	[410]	[106,110]	0	hSpCas9	negative selection	1381642
45264865	45264888	19	+	26627737	RPE1	viability after 18 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.08234247447017795	[703]	[219,180]	0	hSpCas9	negative selection	1381643
45271685	45271708	19	-	26627737	RPE1	viability after 18 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.44913958773571705	[1111]	[327,496]	3	hSpCas9	negative selection	1381644
45251618	45251641	19	+	26627737	HeLa	viability after 8 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.49864826205148227	[806]	[232,168,333]	-5	hSpCas9	negative selection	1463954
45259004	45259027	19	+	26627737	HeLa	viability after 8 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	-0.13349887756597062	[602]	[160,264,271]	-1	hSpCas9	negative selection	1463955
45263315	45263338	19	-	26627737	HeLa	viability after 8 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.409799471775363	[789]	[668,338,411]	4	hSpCas9	negative selection	1463956
45264724	45264747	19	-	26627737	HeLa	viability after 8 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	0.17519199863727009	[277]	[175,54,183]	1	hSpCas9	negative selection	1463957
45264865	45264888	19	+	26627737	HeLa	viability after 8 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.6909011431694246	[241]	[200,59,249]	6	hSpCas9	negative selection	1463958
45271685	45271708	19	-	26627737	HeLa	viability after 8 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	-0.2618743810763664	[875]	[463,205,315]	-3	hSpCas9	negative selection	1463959
45251618	45251641	19	+	26627737	HeLa	viability after 12 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.555721863615699	[806]	[109,370,180]	-5	hSpCas9	negative selection	1546269
45259004	45259027	19	+	26627737	HeLa	viability after 12 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	-0.04155916888231426	[602]	[374,215,141]	0	hSpCas9	negative selection	1546270
45263315	45263338	19	-	26627737	HeLa	viability after 12 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	-0.031753449192549854	[789]	[315,328,311]	0	hSpCas9	negative selection	1546271
45264724	45264747	19	-	26627737	HeLa	viability after 12 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.5849499424513454	[277]	[87,20,126]	-5	hSpCas9	negative selection	1546272
45264865	45264888	19	+	26627737	HeLa	viability after 12 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	-0.01838251418607606	[241]	[108,65,124]	0	hSpCas9	negative selection	1546273
45271685	45271708	19	-	26627737	HeLa	viability after 12 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	-0.015417311977162784	[875]	[323,230,531]	0	hSpCas9	negative selection	1546274
45251618	45251641	19	+	26627737	HeLa	viability after 15 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.14234310677870687	[806]	[379,363,341]	1	hSpCas9	negative selection	1628584
45259004	45259027	19	+	26627737	HeLa	viability after 15 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.446769646881942	[602]	[372,298,330]	3	hSpCas9	negative selection	1628585
45263315	45263338	19	-	26627737	HeLa	viability after 15 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.5255426350663397	[789]	[436,249,721]	4	hSpCas9	negative selection	1628586
45264724	45264747	19	-	26627737	HeLa	viability after 15 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	0.046027972627137315	[277]	[183,80,81]	0	hSpCas9	negative selection	1628587
45264865	45264888	19	+	26627737	HeLa	viability after 15 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.27905187755340793	[241]	[195,73,84]	2	hSpCas9	negative selection	1628588
45271685	45271708	19	-	26627737	HeLa	viability after 15 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	-0.0542685609555702	[875]	[265,365,403]	0	hSpCas9	negative selection	1628589
45251618	45251641	19	+	26627737	HeLa	viability after 18 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.13065973721232682	[806]	[239,312,341]	1	hSpCas9	negative selection	1710899
45259004	45259027	19	+	26627737	HeLa	viability after 18 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.5042740643602399	[602]	[265,260,330]	4	hSpCas9	negative selection	1710900
45263315	45263338	19	-	26627737	HeLa	viability after 18 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.54303029312579	[789]	[300,210,721]	4	hSpCas9	negative selection	1710901
45264724	45264747	19	-	26627737	HeLa	viability after 18 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.014340738044204993	[277]	[114,65,81]	0	hSpCas9	negative selection	1710902
45264865	45264888	19	+	26627737	HeLa	viability after 18 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.3567778020950763	[241]	[146,57,84]	3	hSpCas9	negative selection	1710903
45271685	45271708	19	-	26627737	HeLa	viability after 18 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	-0.05583131169768496	[875]	[172,308,403]	0	hSpCas9	negative selection	1710904
45251618	45251641	19	+	26627737	HCT116	viability after 6 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.6508973666112658	[1373]	[56,181]	-4	hSpCas9	negative selection	1793214
45259004	45259027	19	+	26627737	HCT116	viability after 6 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	1.4444826029732185	[393]	[29,244]	7	hSpCas9	negative selection	1793215
45263315	45263338	19	-	26627737	HCT116	viability after 6 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	1.1459475604340637	[551]	[124,228]	6	hSpCas9	negative selection	1793216
45264724	45264747	19	-	26627737	HCT116	viability after 6 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.3129371335288486	[725]	[165,50]	-2	hSpCas9	negative selection	1793217
45264865	45264888	19	+	26627737	HCT116	viability after 6 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	-3.1578805689299427	[380]	[7,5]	-9	hSpCas9	negative selection	1793218
45271685	45271708	19	-	26627737	HCT116	viability after 6 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.9150590569163892	[1066]	[256,348]	5	hSpCas9	negative selection	1793219
45251618	45251641	19	+	26627737	HCT116	viability after 8 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	1.1425084735855187	[203]	[304,233,206]	8	hSpCas9	negative selection	1875529
45259004	45259027	19	+	26627737	HCT116	viability after 8 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	1.7008675329278917	[114]	[244,190,182]	9	hSpCas9	negative selection	1875530
45263315	45263338	19	-	26627737	HCT116	viability after 8 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	-0.20553072023903973	[548]	[414,131,242]	-2	hSpCas9	negative selection	1875531
45264724	45264747	19	-	26627737	HCT116	viability after 8 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	0.026340653750690946	[145]	[91,73,79]	0	hSpCas9	negative selection	1875532
45264865	45264888	19	+	26627737	HCT116	viability after 8 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.405335062301196	[145]	[85,103,128]	4	hSpCas9	negative selection	1875533
45271685	45271708	19	-	26627737	HCT116	viability after 8 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	-0.0833298907938047	[706]	[334,436,330]	-1	hSpCas9	negative selection	1875534
45251618	45251641	19	+	26627737	HCT116	viability after 9 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.4800598248679079	[1373]	[214,300]	-3	hSpCas9	negative selection	1957844
45259004	45259027	19	+	26627737	HCT116	viability after 9 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.2102621797600333	[393]	[133,111]	1	hSpCas9	negative selection	1957845
45263315	45263338	19	-	26627737	HCT116	viability after 9 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.5587351501231099	[551]	[134,281]	4	hSpCas9	negative selection	1957846
45264724	45264747	19	-	26627737	HCT116	viability after 9 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.17514268671748406	[725]	[83,240]	-1	hSpCas9	negative selection	1957847
45264865	45264888	19	+	26627737	HCT116	viability after 9 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	-0.8745928296602011	[380]	[26,77]	-6	hSpCas9	negative selection	1957848
45271685	45271708	19	-	26627737	HCT116	viability after 9 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	-1.0128688335534752	[1066]	[167,119]	-6	hSpCas9	negative selection	1957849
45251618	45251641	19	+	26627737	HCT116	viability after 12 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	1.6213760534022188	[203]	[298,319,372]	9	hSpCas9	negative selection	2040159
45259004	45259027	19	+	26627737	HCT116	viability after 12 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	1.6468118737090602	[114]	[183,221,162]	9	hSpCas9	negative selection	2040160
45263315	45263338	19	-	26627737	HCT116	viability after 12 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	-0.22037343103378138	[548]	[241,229,270]	-2	hSpCas9	negative selection	2040161
45264724	45264747	19	-	26627737	HCT116	viability after 12 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.1782371717196678	[145]	[87,81,31]	-2	hSpCas9	negative selection	2040162
45264865	45264888	19	+	26627737	HCT116	viability after 12 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.0791284851470554	[145]	[61,87,94]	0	hSpCas9	negative selection	2040163
45271685	45271708	19	-	26627737	HCT116	viability after 12 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.04992806906087588	[706]	[425,373,349]	0	hSpCas9	negative selection	2040164
45251618	45251641	19	+	26627737	HCT116	viability after 15 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	1.1795744302880755	[203]	[300,196,301]	8	hSpCas9	negative selection	2122474
45259004	45259027	19	+	26627737	HCT116	viability after 15 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	1.4430808257795609	[114]	[274,150,124]	9	hSpCas9	negative selection	2122475
45263315	45263338	19	-	26627737	HCT116	viability after 15 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.0595410184389632	[548]	[309,389,283]	0	hSpCas9	negative selection	2122476
45264724	45264747	19	-	26627737	HCT116	viability after 15 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.2443144362243055	[145]	[120,70,26]	-3	hSpCas9	negative selection	2122477
45264865	45264888	19	+	26627737	HCT116	viability after 15 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.41970761408765134	[145]	[138,109,90]	4	hSpCas9	negative selection	2122478
45271685	45271708	19	-	26627737	HCT116	viability after 15 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	-0.2021374997505263	[706]	[377,423,260]	-2	hSpCas9	negative selection	2122479
45251618	45251641	19	+	26627737	HCT116	viability after 18 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	1.488297737731497	[203]	[287,152,402]	9	hSpCas9	negative selection	2204789
45259004	45259027	19	+	26627737	HCT116	viability after 18 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	1.1578389544574343	[114]	[103,124,143]	8	hSpCas9	negative selection	2204790
45263315	45263338	19	-	26627737	HCT116	viability after 18 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	-0.02590600210695715	[548]	[210,315,250]	0	hSpCas9	negative selection	2204791
45264724	45264747	19	-	26627737	HCT116	viability after 18 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	1.3656910962103916	[145]	[386,94,63]	8	hSpCas9	negative selection	2204792
45264865	45264888	19	+	26627737	HCT116	viability after 18 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.4361648781966926	[145]	[87,119,75]	4	hSpCas9	negative selection	2204793
45271685	45271708	19	-	26627737	HCT116	viability after 18 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.35095596037592336	[706]	[609,319,382]	3	hSpCas9	negative selection	2204794
45090124	45090147	19	-	24336569	HL60	viability	ACAGGCACGGGAATGTTCACTGG	MARK4	ENSG00000007047	-0.34278203387366857	[1007]	[1681]	-3	hSpCas9	negative selection	2267772
45090131	45090154	19	+	24336569	HL60	viability	ACATTCCCGTGCCTGTGCTCCGG	MARK4	ENSG00000007047	5.629342333070456	[3]	[418]	9	hSpCas9	negative selection	2267773
45090163	45090186	19	+	24336569	HL60	viability	GGCCCTGATGGCTTCAGCCGTGG	MARK4	ENSG00000007047	-1.220440513777707	[783]	[711]	-8	hSpCas9	negative selection	2267774
45090211	45090234	19	-	24336569	HL60	viability	TCAGGAACCTCTGGCCTCAAGGG	MARK4	ENSG00000007047	-0.49650159990774	[613]	[920]	-4	hSpCas9	negative selection	2267775
45090237	45090260	19	-	24336569	HL60	viability	CTTGAGCTATGGGACACTCCTGG	MARK4	ENSG00000007047	0.10933649160618641	[586]	[1339]	1	hSpCas9	negative selection	2267776
45090246	45090269	19	+	24336569	HL60	viability	TCCCATAGCTCAAGAATCCCTGG	MARK4	ENSG00000007047	-0.32421423500833546	[338]	[572]	-3	hSpCas9	negative selection	2267777
45090255	45090278	19	+	24336569	HL60	viability	TCAAGAATCCCTGGAATCCCAGG	MARK4	ENSG00000007047	-0.5593893058631305	[421]	[605]	-5	hSpCas9	negative selection	2267778
45090263	45090286	19	+	24336569	HL60	viability	CCCTGGAATCCCAGGAGCAGCGG	MARK4	ENSG00000007047	0.002448509051597769	[358]	[760]	0	hSpCas9	negative selection	2267779
45090272	45090295	19	-	24336569	HL60	viability	GGCTCGTGCCCGCTGCTCCTGGG	MARK4	ENSG00000007047	0.7035230084002532	[194]	[671]	6	hSpCas9	negative selection	2267780
45251578	45251601	19	+	24336569	HL60	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.0025462074297903925	[2017]	[4277]	0	hSpCas9	negative selection	2276308
45251588	45251611	19	+	24336569	HL60	viability	GATGTCTTCGCGGACGGTGCTGG	MARK4	ENSG00000007047	0.964190564935474	[831]	[3434]	7	hSpCas9	negative selection	2276309
45251612	45251635	19	+	24336569	HL60	viability	CCCGGGCAACGATCGGAACTCGG	MARK4	ENSG00000007047	-0.10109290737782894	[776]	[1532]	-1	hSpCas9	negative selection	2276310
45251618	45251641	19	+	24336569	HL60	viability	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.15334570462562758	[941]	[2216]	1	hSpCas9	negative selection	2276311
45258980	45259003	19	+	24336569	HL60	viability	CCCGCCCAGCATGGCACCTTGGG	MARK4	ENSG00000007047	0.48561352177995976	[486]	[1442]	4	hSpCas9	negative selection	2276312
45258985	45259008	19	-	24336569	HL60	viability	CACTGCCCAAGGTGCCATGCTGG	MARK4	ENSG00000007047	0.3911244212121059	[515]	[1431]	3	hSpCas9	negative selection	2276313
45258996	45259019	19	-	24336569	HL60	viability	CGAGGAGCGGCCACTGCCCAAGG	MARK4	ENSG00000007047	0.846358341440651	[332]	[1266]	7	hSpCas9	negative selection	2276314
45259004	45259027	19	+	24336569	HL60	viability	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	-0.1944730624580826	[510]	[944]	-2	hSpCas9	negative selection	2276315
45259009	45259032	19	-	24336569	HL60	viability	ACGGGCCTTTGTCCGAGGAGCGG	MARK4	ENSG00000007047	0.8331621437592276	[495]	[1869]	6	hSpCas9	negative selection	2276316
45259014	45259037	19	-	24336569	HL60	viability	CCAGGACGGGCCTTTGTCCGAGG	MARK4	ENSG00000007047	0.47205535244137875	[200]	[589]	4	hSpCas9	negative selection	2276317
45090124	45090147	19	-	24336569	KBM7	viability	ACAGGCACGGGAATGTTCACTGG	MARK4	ENSG00000007047	0.11490200608348622	[926]	[2737]	1	hSpCas9	negative selection	2334949
45090131	45090154	19	+	24336569	KBM7	viability	ACATTCCCGTGCCTGTGCTCCGG	MARK4	ENSG00000007047	-0.12565110166152038	[203]	[509]	-1	hSpCas9	negative selection	2334950
45090163	45090186	19	+	24336569	KBM7	viability	GGCCCTGATGGCTTCAGCCGTGG	MARK4	ENSG00000007047	0.9145193368140141	[339]	[1747]	7	hSpCas9	negative selection	2334951
45090211	45090234	19	-	24336569	KBM7	viability	TCAGGAACCTCTGGCCTCAAGGG	MARK4	ENSG00000007047	1.2713446075225046	[172]	[1138]	9	hSpCas9	negative selection	2334952
45090237	45090260	19	-	24336569	KBM7	viability	CTTGAGCTATGGGACACTCCTGG	MARK4	ENSG00000007047	-0.39228106311408983	[690]	[1435]	-3	hSpCas9	negative selection	2334953
45090246	45090269	19	+	24336569	KBM7	viability	TCCCATAGCTCAAGAATCCCTGG	MARK4	ENSG00000007047	-0.5026505790425583	[266]	[513]	-4	hSpCas9	negative selection	2334954
45090255	45090278	19	+	24336569	KBM7	viability	TCAAGAATCCCTGGAATCCCAGG	MARK4	ENSG00000007047	0.4894895477246608	[122]	[470]	4	hSpCas9	negative selection	2334955
45090263	45090286	19	+	24336569	KBM7	viability	CCCTGGAATCCCAGGAGCAGCGG	MARK4	ENSG00000007047	-0.7284800231761903	[129]	[213]	-5	hSpCas9	negative selection	2334956
45090272	45090295	19	-	24336569	KBM7	viability	GGCTCGTGCCCGCTGCTCCTGGG	MARK4	ENSG00000007047	0.15737477935973987	[214]	[653]	1	hSpCas9	negative selection	2334957
45251578	45251601	19	+	24336569	KBM7	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.7180573382862048	[860]	[3862]	6	hSpCas9	negative selection	2343485
45251588	45251611	19	+	24336569	KBM7	viability	GATGTCTTCGCGGACGGTGCTGG	MARK4	ENSG00000007047	0.3072020727776845	[1005]	[3394]	3	hSpCas9	negative selection	2343486
45251612	45251635	19	+	24336569	KBM7	viability	CCCGGGCAACGATCGGAACTCGG	MARK4	ENSG00000007047	0.5919491676377547	[674]	[2774]	5	hSpCas9	negative selection	2343487
45251618	45251641	19	+	24336569	KBM7	viability	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.8459204900119625	[614]	[3014]	7	hSpCas9	negative selection	2343488
45258980	45259003	19	+	24336569	KBM7	viability	CCCGCCCAGCATGGCACCTTGGG	MARK4	ENSG00000007047	0.98791145716168	[463]	[2509]	8	hSpCas9	negative selection	2343489
45258985	45259008	19	-	24336569	KBM7	viability	CACTGCCCAAGGTGCCATGCTGG	MARK4	ENSG00000007047	0.46706973868062995	[543]	[2050]	4	hSpCas9	negative selection	2343490
45258996	45259019	19	-	24336569	KBM7	viability	CGAGGAGCGGCCACTGCCCAAGG	MARK4	ENSG00000007047	0.037847630621359235	[424]	[1189]	0	hSpCas9	negative selection	2343491
45259004	45259027	19	+	24336569	KBM7	viability	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.4913556522653855	[373]	[1433]	4	hSpCas9	negative selection	2343492
45259009	45259032	19	-	24336569	KBM7	viability	ACGGGCCTTTGTCCGAGGAGCGG	MARK4	ENSG00000007047	0.6820933694846905	[528]	[2314]	6	hSpCas9	negative selection	2343493
45259014	45259037	19	-	24336569	KBM7	viability	CCAGGACGGGCCTTTGTCCGAGG	MARK4	ENSG00000007047	1.910549540054051	[121]	[1250]	9	hSpCas9	negative selection	2343494
45257457	45257480	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCTGCCTCCCTGG	MARK4	ENSG00000007047	-0.8346021834980462	[246,704]	[74,41]	-5	dCas9-VP64	positive selection	2386364
45261888	45261911	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCATTGCACTCCAGCCTGAG	MARK4	ENSG00000007047	-0.7836007518198642	[44,14]	[5,0]	-4	dCas9-VP64	positive selection	2394632
45283257	45283280	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAATTAGCCGGGCGTAGTGGCAG	MARK4	ENSG00000007047	-0.8514681672512537	[13,97]	[5,6]	-5	dCas9-VP64	positive selection	2404259
45178403	45178426	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGCGGGCCTACGCCTTCTCTGG	MARK4	ENSG00000007047	-0.3127346267467168	[589,32]	[99,3]	-1	dCas9-VP64	positive selection	2455773
45178372	45178395	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTGGTGTGCGCGTGAGCCTGGG	MARK4	ENSG00000007047	-0.8259883667405802	[210,49]	[20,9]	-4	dCas9-VP64	positive selection	2455774
45178321	45178344	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTAAAACACCAATGGAAGCCGG	MARK4	ENSG00000007047	0.6663899350986267	[259,144]	[127,7]	3	dCas9-VP64	positive selection	2455775
45251073	45251096	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGCACTGGAGAGGAGAGAAGG	MARK4	ENSG00000007047	3.367344540587422	[9,29]	[63,27]	8	dCas9-VP64	positive selection	2458300
45251122	45251145	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGGGTCTGGGCACGCCGGCGG	MARK4	ENSG00000007047	0.9471880163008133	[6,3]	[1,0]	4	dCas9-VP64	positive selection	2458301
45251094	45251117	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTTCTCGCCCGAGACGAGAGG	MARK4	ENSG00000007047	2.2571886399622167	[38,9]	[6,45]	7	dCas9-VP64	positive selection	2458302
45234281	45234304	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCGGCTACCACGGGGCCCTGG	MARK4	ENSG00000007047	0.5048159245772952	[24,5]	[5,2]	2	dCas9-VP64	positive selection	2464182
45234368	45234391	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGCGGCTGCTGGAGGATATGG	MARK4	ENSG00000007047	1.129233607542261	[118,3]	[47,8]	4	dCas9-VP64	positive selection	2464183
45234305	45234328	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTAGACGCCGAAGGCGCCCAGG	MARK4	ENSG00000007047	1.431321949334311	[3,15]	[0,10]	5	dCas9-VP64	positive selection	2464184
45160287	45160310	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAAGGCCAAGTCCCAGATGCTGG	MARK4	ENSG00000007047	-1.0805351362699285	[39,239]	[6,21]	-6	dCas9-VP64	positive selection	2474714
45160227	45160250	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCACGAACAGCAGAGAGCTGAGG	MARK4	ENSG00000007047	3.1581838587426145	[39,25]	[6,127]	8	dCas9-VP64	positive selection	2474715
45160311	45160334	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTCCTAGGTCACTTGGGAGAAGG	MARK4	ENSG00000007047	-1.7077135826087606	[83,45]	[5,1]	-8	dCas9-VP64	positive selection	2474716
45178592	45178615	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCGCCAATAGAGAAACAGCTGG	MARK4	ENSG00000007047	1.8918293337252947	[43,374]	[12,346]	6	dCas9-VP64	positive selection	2478223
45178568	45178591	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTCGCACAACCTGGAAGAGCCGG	MARK4	ENSG00000007047	1.3314169970264271	[296,414]	[249,141]	5	dCas9-VP64	positive selection	2478224
45178619	45178642	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCAGAAGAGTCACATGAATGG	MARK4	ENSG00000007047	1.5117114745501072	[87,85]	[26,82]	5	dCas9-VP64	positive selection	2478225
45257457	45257480	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCTGCCTCCCTGG	MARK4	ENSG00000007047	0.6564409522361534	[325,125]	[135,99]	5	dCas9-VP64	positive selection	2481619
45261888	45261911	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCATTGCACTCCAGCCTGAG	MARK4	ENSG00000007047	-1.3426926137865989	[87,148]	[18,10]	-9	dCas9-VP64	positive selection	2489887
45283257	45283280	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAATTAGCCGGGCGTAGTGGCAG	MARK4	ENSG00000007047	0.40157018881037165	[169,39]	[83,8]	3	dCas9-VP64	positive selection	2499514
45178403	45178426	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGCGGGCCTACGCCTTCTCTGG	MARK4	ENSG00000007047	1.872144206959152	[108,46]	[179,13]	8	dCas9-VP64	positive selection	2551028
45178372	45178395	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTGGTGTGCGCGTGAGCCTGGG	MARK4	ENSG00000007047	0.5727535337421985	[18,67]	[18,21]	4	dCas9-VP64	positive selection	2551029
45178321	45178344	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTAAAACACCAATGGAAGCCGG	MARK4	ENSG00000007047	0.9035285410034141	[133,96]	[19,117]	6	dCas9-VP64	positive selection	2551030
45251073	45251096	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGCACTGGAGAGGAGAGAAGG	MARK4	ENSG00000007047	0.9817369132787197	[232,61]	[113,78]	6	dCas9-VP64	positive selection	2553555
45251122	45251145	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGGGTCTGGGCACGCCGGCGG	MARK4	ENSG00000007047	-0.2207975551417376	[18,8]	[5,0]	-2	dCas9-VP64	positive selection	2553556
45251094	45251117	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTTCTCGCCCGAGACGAGAGG	MARK4	ENSG00000007047	-0.10342172462297092	[153,93]	[36,37]	-1	dCas9-VP64	positive selection	2553557
45234281	45234304	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCGGCTACCACGGGGCCCTGG	MARK4	ENSG00000007047	0.3968703294760167	[34,253]	[10,107]	3	dCas9-VP64	positive selection	2559437
45234368	45234391	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGCGGCTGCTGGAGGATATGG	MARK4	ENSG00000007047	-0.161462464341819	[56,26]	[17,5]	-1	dCas9-VP64	positive selection	2559438
45234305	45234328	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTAGACGCCGAAGGCGCCCAGG	MARK4	ENSG00000007047	-0.2895620713676586	[43,131]	[17,26]	-3	dCas9-VP64	positive selection	2559439
45160287	45160310	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAAGGCCAAGTCCCAGATGCTGG	MARK4	ENSG00000007047	3.892179510276213	[79,68]	[709,40]	9	dCas9-VP64	positive selection	2569969
45160227	45160250	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCACGAACAGCAGAGAGCTGAGG	MARK4	ENSG00000007047	-0.014966103327431313	[103,41]	[33,12]	0	dCas9-VP64	positive selection	2569970
45160311	45160334	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTCCTAGGTCACTTGGGAGAAGG	MARK4	ENSG00000007047	-1.3435443448396975	[160,270]	[25,27]	-9	dCas9-VP64	positive selection	2569971
45178592	45178615	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCGCCAATAGAGAAACAGCTGG	MARK4	ENSG00000007047	1.0519401962815305	[26,100]	[74,11]	6	dCas9-VP64	positive selection	2573478
45178568	45178591	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTCGCACAACCTGGAAGAGCCGG	MARK4	ENSG00000007047	0.021087802652155097	[149,108]	[55,29]	0	dCas9-VP64	positive selection	2573479
45178619	45178642	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCAGAAGAGTCACATGAATGG	MARK4	ENSG00000007047	-0.8042759599932816	[144,114]	[38,9]	-7	dCas9-VP64	positive selection	2573480
45259097	45259120	19	-	27260157	DLD1	viability	AGGCGGTAGTTGCCCACGTGGGG	MARK4	ENSG00000007047	-0.088246143284326	[]	[]	0	hSpCas9	negative selection	2574665
45258985	45259008	19	-	27260157	DLD1	viability	CACTGCCCAAGGTGCCATGCTGG	MARK4	ENSG00000007047	0.127423857092248	[]	[]	3	hSpCas9	negative selection	2580986
45251612	45251635	19	+	27260157	DLD1	viability	CCCGGGCAACGATCGGAACTCGG	MARK4	ENSG00000007047	-0.394245526806053	[]	[]	-3	hSpCas9	negative selection	2583837
45259056	45259079	19	-	27260157	DLD1	viability	GGCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.319418653061342	[]	[]	4	hSpCas9	negative selection	2584019
45251611	45251634	19	-	27260157	DLD1	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-1.50237776490655	[]	[]	-8	hSpCas9	negative selection	2584181
45259014	45259037	19	+	27260157	DLD1	viability	CCTCGGACAAAGGCCCGTCCTGG	MARK4	ENSG00000007047	0.66335026241285	[]	[]	8	hSpCas9	negative selection	2584271
45259141	45259164	19	+	27260157	DLD1	viability	CAACTTTGCCAAAGTCAAGCTGG	MARK4	ENSG00000007047	0.894902481484587	[]	[]	9	hSpCas9	negative selection	2587070
45259038	45259061	19	-	27260157	DLD1	viability	ACGGGCACCCAGTGAGCGGCTGG	MARK4	ENSG00000007047	0.766759875655293	[]	[]	8	hSpCas9	negative selection	2587114
45259004	45259027	19	+	27260157	DLD1	viability	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.748757476061636	[]	[]	8	hSpCas9	negative selection	2606553
45258980	45259003	19	+	27260157	DLD1	viability	CCCGCCCAGCATGGCACCTTGGG	MARK4	ENSG00000007047	1.01379062000135	[]	[]	9	hSpCas9	negative selection	2608980
45259149	45259172	19	-	27260157	DLD1	viability	GTGCCGAGCCAGCTTGACTTTGG	MARK4	ENSG00000007047	0.735509695709732	[]	[]	8	hSpCas9	negative selection	2609447
45258996	45259019	19	-	27260157	DLD1	viability	CGAGGAGCGGCCACTGCCCAAGG	MARK4	ENSG00000007047	0.345454518217443	[]	[]	4	hSpCas9	negative selection	2612693
45251618	45251641	19	+	27260157	DLD1	viability	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.227365763231961	[]	[]	-2	hSpCas9	negative selection	2615742
45259044	45259067	19	+	27260157	DLD1	viability	GCTCACTGGGTGCCCGTTGCCGG	MARK4	ENSG00000007047	0.209064621316408	[]	[]	3	hSpCas9	negative selection	2615942
45259117	45259140	19	+	27260157	DLD1	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	1.03593612806707	[]	[]	9	hSpCas9	negative selection	2621422
45259009	45259032	19	-	27260157	DLD1	viability	ACGGGCCTTTGTCCGAGGAGCGG	MARK4	ENSG00000007047	0.321948001533519	[]	[]	4	hSpCas9	negative selection	2623384
45259014	45259037	19	-	27260157	DLD1	viability	CCAGGACGGGCCTTTGTCCGAGG	MARK4	ENSG00000007047	0.740159700802759	[]	[]	8	hSpCas9	negative selection	2649436
45259097	45259120	19	-	27260157	HT1080	viability	AGGCGGTAGTTGCCCACGTGGGG	MARK4	ENSG00000007047	-0.73773936114333	[]	[]	-8	hSpCas9	negative selection	2650795
45258985	45259008	19	-	27260157	HT1080	viability	CACTGCCCAAGGTGCCATGCTGG	MARK4	ENSG00000007047	0.246104146830168	[]	[]	2	hSpCas9	negative selection	2657116
45251612	45251635	19	+	27260157	HT1080	viability	CCCGGGCAACGATCGGAACTCGG	MARK4	ENSG00000007047	-0.023372767280269	[]	[]	0	hSpCas9	negative selection	2659967
45259056	45259079	19	-	27260157	HT1080	viability	GGCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	-0.780932376351128	[]	[]	-8	hSpCas9	negative selection	2660149
45251611	45251634	19	-	27260157	HT1080	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-1.38457384091824	[]	[]	-9	hSpCas9	negative selection	2660311
45259014	45259037	19	+	27260157	HT1080	viability	CCTCGGACAAAGGCCCGTCCTGG	MARK4	ENSG00000007047	0.279742201626497	[]	[]	2	hSpCas9	negative selection	2660401
45259141	45259164	19	+	27260157	HT1080	viability	CAACTTTGCCAAAGTCAAGCTGG	MARK4	ENSG00000007047	0.660092005956298	[]	[]	6	hSpCas9	negative selection	2663200
45259038	45259061	19	-	27260157	HT1080	viability	ACGGGCACCCAGTGAGCGGCTGG	MARK4	ENSG00000007047	0.615114485885057	[]	[]	5	hSpCas9	negative selection	2663244
45259004	45259027	19	+	27260157	HT1080	viability	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.203600352867807	[]	[]	2	hSpCas9	negative selection	2682683
45258980	45259003	19	+	27260157	HT1080	viability	CCCGCCCAGCATGGCACCTTGGG	MARK4	ENSG00000007047	-0.207770552245007	[]	[]	0	hSpCas9	negative selection	2685110
45259149	45259172	19	-	27260157	HT1080	viability	GTGCCGAGCCAGCTTGACTTTGG	MARK4	ENSG00000007047	-1.09724600500307	[]	[]	-8	hSpCas9	negative selection	2685577
45258996	45259019	19	-	27260157	HT1080	viability	CGAGGAGCGGCCACTGCCCAAGG	MARK4	ENSG00000007047	-0.318045945513046	[]	[]	-7	hSpCas9	negative selection	2688823
45251618	45251641	19	+	27260157	HT1080	viability	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.515915156761568	[]	[]	4	hSpCas9	negative selection	2691872
45259044	45259067	19	+	27260157	HT1080	viability	GCTCACTGGGTGCCCGTTGCCGG	MARK4	ENSG00000007047	-1.20505214315928	[]	[]	-8	hSpCas9	negative selection	2692072
45259117	45259140	19	+	27260157	HT1080	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	0.930621978897736	[]	[]	7	hSpCas9	negative selection	2697552
45259009	45259032	19	-	27260157	HT1080	viability	ACGGGCCTTTGTCCGAGGAGCGG	MARK4	ENSG00000007047	0.505442857575042	[]	[]	4	hSpCas9	negative selection	2699514
45259014	45259037	19	-	27260157	HT1080	viability	CCAGGACGGGCCTTTGTCCGAGG	MARK4	ENSG00000007047	-0.0442265551707908	[]	[]	0	hSpCas9	negative selection	2725566
45259097	45259120	19	-	27260157	MKN45	viability	AGGCGGTAGTTGCCCACGTGGGG	MARK4	ENSG00000007047	-0.136182768559857	[]	[]	0	hSpCas9	negative selection	2726925
45258985	45259008	19	-	27260157	MKN45	viability	CACTGCCCAAGGTGCCATGCTGG	MARK4	ENSG00000007047	-0.116692246332401	[]	[]	0	hSpCas9	negative selection	2733246
45251612	45251635	19	+	27260157	MKN45	viability	CCCGGGCAACGATCGGAACTCGG	MARK4	ENSG00000007047	0.241248575898694	[]	[]	5	hSpCas9	negative selection	2736097
45259056	45259079	19	-	27260157	MKN45	viability	GGCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.481796032228329	[]	[]	6	hSpCas9	negative selection	2736279
45251611	45251634	19	-	27260157	MKN45	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-1.9771807654298	[]	[]	-9	hSpCas9	negative selection	2736441
45259014	45259037	19	+	27260157	MKN45	viability	CCTCGGACAAAGGCCCGTCCTGG	MARK4	ENSG00000007047	-0.1464450506395	[]	[]	0	hSpCas9	negative selection	2736531
45259141	45259164	19	+	27260157	MKN45	viability	CAACTTTGCCAAAGTCAAGCTGG	MARK4	ENSG00000007047	0.513409513182336	[]	[]	6	hSpCas9	negative selection	2739330
45259038	45259061	19	-	27260157	MKN45	viability	ACGGGCACCCAGTGAGCGGCTGG	MARK4	ENSG00000007047	0.521654104730765	[]	[]	6	hSpCas9	negative selection	2739374
45259004	45259027	19	+	27260157	MKN45	viability	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	1.1944666818973	[]	[]	9	hSpCas9	negative selection	2758813
45258980	45259003	19	+	27260157	MKN45	viability	CCCGCCCAGCATGGCACCTTGGG	MARK4	ENSG00000007047	0.143790857990073	[]	[]	5	hSpCas9	negative selection	2761240
45259149	45259172	19	-	27260157	MKN45	viability	GTGCCGAGCCAGCTTGACTTTGG	MARK4	ENSG00000007047	0.53255471792369	[]	[]	6	hSpCas9	negative selection	2761707
45258996	45259019	19	-	27260157	MKN45	viability	CGAGGAGCGGCCACTGCCCAAGG	MARK4	ENSG00000007047	0.219793454317463	[]	[]	5	hSpCas9	negative selection	2764953
45251618	45251641	19	+	27260157	MKN45	viability	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.446059430472395	[]	[]	6	hSpCas9	negative selection	2768002
45259044	45259067	19	+	27260157	MKN45	viability	GCTCACTGGGTGCCCGTTGCCGG	MARK4	ENSG00000007047	-0.456420127369587	[]	[]	-6	hSpCas9	negative selection	2768202
45259117	45259140	19	+	27260157	MKN45	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	1.16416380801732	[]	[]	8	hSpCas9	negative selection	2773682
45259009	45259032	19	-	27260157	MKN45	viability	ACGGGCCTTTGTCCGAGGAGCGG	MARK4	ENSG00000007047	0.656897449606673	[]	[]	7	hSpCas9	negative selection	2775644
45259014	45259037	19	-	27260157	MKN45	viability	CCAGGACGGGCCTTTGTCCGAGG	MARK4	ENSG00000007047	0.823031121399762	[]	[]	8	hSpCas9	negative selection	2801696
45259097	45259120	19	-	27260157	RKO	viability	AGGCGGTAGTTGCCCACGTGGGG	MARK4	ENSG00000007047	-0.0475636531837472	[]	[]	0	hSpCas9	negative selection	2803055
45258985	45259008	19	-	27260157	RKO	viability	CACTGCCCAAGGTGCCATGCTGG	MARK4	ENSG00000007047	0.471961136614264	[]	[]	2	hSpCas9	negative selection	2809376
45251612	45251635	19	+	27260157	RKO	viability	CCCGGGCAACGATCGGAACTCGG	MARK4	ENSG00000007047	0.331521741863531	[]	[]	1	hSpCas9	negative selection	2812227
45259056	45259079	19	-	27260157	RKO	viability	GGCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.308164843278035	[]	[]	1	hSpCas9	negative selection	2812409
45251611	45251634	19	-	27260157	RKO	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-1.5751031614664	[]	[]	-9	hSpCas9	negative selection	2812571
45259014	45259037	19	+	27260157	RKO	viability	CCTCGGACAAAGGCCCGTCCTGG	MARK4	ENSG00000007047	0.201012171665578	[]	[]	1	hSpCas9	negative selection	2812661
45259141	45259164	19	+	27260157	RKO	viability	CAACTTTGCCAAAGTCAAGCTGG	MARK4	ENSG00000007047	0.946489697209088	[]	[]	8	hSpCas9	negative selection	2815460
45259038	45259061	19	-	27260157	RKO	viability	ACGGGCACCCAGTGAGCGGCTGG	MARK4	ENSG00000007047	0.603580756590134	[]	[]	3	hSpCas9	negative selection	2815504
45259004	45259027	19	+	27260157	RKO	viability	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.783022373724096	[]	[]	8	hSpCas9	negative selection	2834943
45258980	45259003	19	+	27260157	RKO	viability	CCCGCCCAGCATGGCACCTTGGG	MARK4	ENSG00000007047	0.52345903442477	[]	[]	2	hSpCas9	negative selection	2837370
45259149	45259172	19	-	27260157	RKO	viability	GTGCCGAGCCAGCTTGACTTTGG	MARK4	ENSG00000007047	0.623444449159394	[]	[]	3	hSpCas9	negative selection	2837837
45258996	45259019	19	-	27260157	RKO	viability	CGAGGAGCGGCCACTGCCCAAGG	MARK4	ENSG00000007047	-0.0232336989664688	[]	[]	0	hSpCas9	negative selection	2841083
45251618	45251641	19	+	27260157	RKO	viability	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.0885815667335578	[]	[]	0	hSpCas9	negative selection	2844132
45259044	45259067	19	+	27260157	RKO	viability	GCTCACTGGGTGCCCGTTGCCGG	MARK4	ENSG00000007047	-0.0783786487963028	[]	[]	0	hSpCas9	negative selection	2844332
45259117	45259140	19	+	27260157	RKO	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	0.398914936003069	[]	[]	2	hSpCas9	negative selection	2849812
45259009	45259032	19	-	27260157	RKO	viability	ACGGGCCTTTGTCCGAGGAGCGG	MARK4	ENSG00000007047	0.510221780264536	[]	[]	2	hSpCas9	negative selection	2851774
45259014	45259037	19	-	27260157	RKO	viability	CCAGGACGGGCCTTTGTCCGAGG	MARK4	ENSG00000007047	0.859203537197413	[]	[]	8	hSpCas9	negative selection	2877826
45259097	45259120	19	-	27260157	SF268	viability	AGGCGGTAGTTGCCCACGTGGGG	MARK4	ENSG00000007047	0.0137952760640981	[]	[]	0	hSpCas9	negative selection	2879185
45258985	45259008	19	-	27260157	SF268	viability	CACTGCCCAAGGTGCCATGCTGG	MARK4	ENSG00000007047	0.231321559345265	[]	[]	3	hSpCas9	negative selection	2885506
45251612	45251635	19	+	27260157	SF268	viability	CCCGGGCAACGATCGGAACTCGG	MARK4	ENSG00000007047	0.206379233760704	[]	[]	3	hSpCas9	negative selection	2888357
45259056	45259079	19	-	27260157	SF268	viability	GGCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.551574550574886	[]	[]	8	hSpCas9	negative selection	2888539
45251611	45251634	19	-	27260157	SF268	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-1.51840204577573	[]	[]	-8	hSpCas9	negative selection	2888701
45259014	45259037	19	+	27260157	SF268	viability	CCTCGGACAAAGGCCCGTCCTGG	MARK4	ENSG00000007047	0.110188110775474	[]	[]	0	hSpCas9	negative selection	2888791
45259141	45259164	19	+	27260157	SF268	viability	CAACTTTGCCAAAGTCAAGCTGG	MARK4	ENSG00000007047	0.63775868495066	[]	[]	8	hSpCas9	negative selection	2891590
45259038	45259061	19	-	27260157	SF268	viability	ACGGGCACCCAGTGAGCGGCTGG	MARK4	ENSG00000007047	0.969669799981189	[]	[]	9	hSpCas9	negative selection	2891634
45259004	45259027	19	+	27260157	SF268	viability	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.158444273531906	[]	[]	0	hSpCas9	negative selection	2911073
45258980	45259003	19	+	27260157	SF268	viability	CCCGCCCAGCATGGCACCTTGGG	MARK4	ENSG00000007047	0.426166554178279	[]	[]	4	hSpCas9	negative selection	2913500
45259149	45259172	19	-	27260157	SF268	viability	GTGCCGAGCCAGCTTGACTTTGG	MARK4	ENSG00000007047	-0.101993689585176	[]	[]	-1	hSpCas9	negative selection	2913967
45258996	45259019	19	-	27260157	SF268	viability	CGAGGAGCGGCCACTGCCCAAGG	MARK4	ENSG00000007047	0.269002139963938	[]	[]	4	hSpCas9	negative selection	2917213
45251618	45251641	19	+	27260157	SF268	viability	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.24025525910521	[]	[]	-2	hSpCas9	negative selection	2920262
45259044	45259067	19	+	27260157	SF268	viability	GCTCACTGGGTGCCCGTTGCCGG	MARK4	ENSG00000007047	-1.05390453917356	[]	[]	-7	hSpCas9	negative selection	2920462
45259117	45259140	19	+	27260157	SF268	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	0.887557028409262	[]	[]	9	hSpCas9	negative selection	2925942
45259009	45259032	19	-	27260157	SF268	viability	ACGGGCCTTTGTCCGAGGAGCGG	MARK4	ENSG00000007047	0.195220677302033	[]	[]	3	hSpCas9	negative selection	2927904
45259014	45259037	19	-	27260157	SF268	viability	CCAGGACGGGCCTTTGTCCGAGG	MARK4	ENSG00000007047	0.968234728175381	[]	[]	9	hSpCas9	negative selection	2953956
45271590	45271613	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTGCCCTGAAACAGCTCCGGGG	MARK4	ENSG00000007047	0.5186527791865726	[3,3]	[3,4]	9	hSpCas9	positive selection	3001353
45264856	45264879	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCATGCGGCCATGCGACACGAGG	MARK4	ENSG00000007047	0.018613236008209716	[3,3]	[1,3]	0	hSpCas9	positive selection	3001354
45271685	45271708	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.08417475285589054	[5,5]	[4,4]	1	hSpCas9	positive selection	3001355
45271602	45271625	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCAGGGCAAGAAGTACGACGG	MARK4	ENSG00000007047	-0.5789522130177795	[2,2]	[2,0]	-7	hSpCas9	positive selection	3001356
45271590	45271613	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTGCCCTGAAACAGCTCCGGGG	MARK4	ENSG00000007047	-0.9495800458238345	[3,3]	[1,0]	-9	hSpCas9	positive selection	3069211
45264856	45264879	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCATGCGGCCATGCGACACGAGG	MARK4	ENSG00000007047	-0.18440118685259288	[3,3]	[1,1]	-3	hSpCas9	positive selection	3069212
45271685	45271708	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.08109391158576695	[5,5]	[5,2]	1	hSpCas9	positive selection	3069213
45271602	45271625	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCAGGGCAAGAAGTACGACGG	MARK4	ENSG00000007047	-0.17296707448225823	[2,2]	[3,0]	-3	hSpCas9	positive selection	3069214
45251578	45251601		+	24336571	A375	resistance to PLX after 7 days	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.005559024953574963	[13,11]	[12,12]	0	hSpCas9	positive selection	3126495
45263117	45263140		-	24336571	A375	resistance to PLX after 7 days	GGTTTTGTCGATAATCTTGATGG	MARK4	ENSG00000007047	-0.633083157874303	[9,10]	[6,6]	-9	hSpCas9	positive selection	3126496
45251613	45251636		-	24336571	A375	resistance to PLX after 7 days	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.10918821024777081	[31,28]	[28,26]	-3	hSpCas9	positive selection	3126497
45251578	45251601		+	24336571	A375	resistance to PLX after 14 days	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	-1.022621036214632	[9,20]	[2,2]	-9	hSpCas9	positive selection	3184288
45263117	45263140		-	24336571	A375	resistance to PLX after 14 days	GGTTTTGTCGATAATCTTGATGG	MARK4	ENSG00000007047	-1.0368828915820116	[8,11]	[1,1]	-9	hSpCas9	positive selection	3184289
45251613	45251636		-	24336571	A375	resistance to PLX after 14 days	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.13414634935867098	[29,25]	[9,13]	-1	hSpCas9	positive selection	3184290
45251578	45251601		+	24336571	A375	viability after 7 days	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.1275413990071141	[11]	[13,11]	2	hSpCas9	negative selection	3242081
45263117	45263140		-	24336571	A375	viability after 7 days	GGTTTTGTCGATAATCTTGATGG	MARK4	ENSG00000007047	-0.6297109087091917	[16]	[9,10]	-7	hSpCas9	negative selection	3242082
45251613	45251636		-	24336571	A375	viability after 7 days	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.1205327683617261	[28]	[31,28]	1	hSpCas9	negative selection	3242083
45251578	45251601		+	24336571	A375	viability after 14 days	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.4482333777600135	[11]	[9,20]	6	hSpCas9	negative selection	3299874
45263117	45263140		-	24336571	A375	viability after 14 days	GGTTTTGTCGATAATCTTGATGG	MARK4	ENSG00000007047	-0.5995164571025865	[16]	[8,11]	-6	hSpCas9	negative selection	3299875
45251613	45251636		-	24336571	A375	viability after 14 days	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.02710656302127079	[28]	[29,25]	0	hSpCas9	negative selection	3299876
45263354	45263377	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	1.797894592808538	[43,43]	[0,0]	7	hSpCas9	positive selection	3378566
45263150	45263173	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	-0.9569929093549306	[296,296]	[0,0]	-6	hSpCas9	positive selection	3378567
45263145	45263168	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.02850752094995433	[149,149]	[0,0]	0	hSpCas9	positive selection	3378568
45271590	45271613	19	-	26780180	HT29	viability (Avana library 4 designs)	CTTGCCCTGAAACAGCTCCGGGG	MARK4	ENSG00000007047	1.14603407445289	[]	[]	4	hSpCas9	negative selection	3439049
45264856	45264879	19	-	26780180	HT29	viability (Avana library 4 designs)	TCATGCGGCCATGCGACACGAGG	MARK4	ENSG00000007047	0.764160767370776	[]	[]	3	hSpCas9	negative selection	3439050
45271685	45271708	19	-	26780180	HT29	viability (Avana library 4 designs)	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	-0.0149749237393227	[]	[]	0	hSpCas9	negative selection	3439051
45271601	45271624	19	+	26780180	HT29	viability (Avana library 4 designs)	TTTCAGGGCAAGAAGTACGACGG	MARK4	ENSG00000007047	1.42776976287403	[]	[]	5	hSpCas9	negative selection	3439052
45264856	45264879	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCATGCGGCCATGCGACACGAGG	MARK4	ENSG00000007047	2.72539347008618	[]	[]	4	hSpCas9	negative selection	3528601
45271590	45271613	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGCCCTGAAACAGCTCCGGGG	MARK4	ENSG00000007047	1.04182423580045	[]	[]	1	hSpCas9	negative selection	3528602
45271685	45271708	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	5.28404106950222	[]	[]	8	hSpCas9	negative selection	3528603
45271601	45271624	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCAGGGCAAGAAGTACGACGG	MARK4	ENSG00000007047	-0.43741675969655	[]	[]	0	hSpCas9	negative selection	3528604
45264904	45264927	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCCCTGCCCCAACCTGTCGG	MARK4	ENSG00000007047	-2.01590274379493	[]	[]	-2	hSpCas9	negative selection	3528605
45263325	45263348	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGAGAAGTCCGCATCATGAAGGG	MARK4	ENSG00000007047	2.46218425204655	[]	[]	3	hSpCas9	negative selection	3528606
45264856	45264879	19	-	26780180	A375	viability (Avana lentiGuide)	TCATGCGGCCATGCGACACGAGG	MARK4	ENSG00000007047	-2.42271874555768	[]	[]	-4	hSpCas9	negative selection	3637260
45271590	45271613	19	-	26780180	A375	viability (Avana lentiGuide)	CTTGCCCTGAAACAGCTCCGGGG	MARK4	ENSG00000007047	-0.255121105339079	[]	[]	0	hSpCas9	negative selection	3637261
45271685	45271708	19	-	26780180	A375	viability (Avana lentiGuide)	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.845886058388366	[]	[]	1	hSpCas9	negative selection	3637262
45271601	45271624	19	+	26780180	A375	viability (Avana lentiGuide)	TTTCAGGGCAAGAAGTACGACGG	MARK4	ENSG00000007047	-4.35055294579195	[]	[]	-7	hSpCas9	negative selection	3637263
45264904	45264927	19	-	26780180	A375	viability (Avana lentiGuide)	TCAGCCCTGCCCCAACCTGTCGG	MARK4	ENSG00000007047	4.28493481514688	[]	[]	4	hSpCas9	negative selection	3637264
45263325	45263348	19	+	26780180	A375	viability (Avana lentiGuide)	CGAGAAGTCCGCATCATGAAGGG	MARK4	ENSG00000007047	-1.49279469429369	[]	[]	-2	hSpCas9	negative selection	3637265
45264856	45264879	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATGCGGCCATGCGACACGAGG	MARK4	ENSG00000007047	0.14797228220223274	[3]	[4,4]	4	hSpCas9	positive selection	3745919
45271590	45271613	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGCCCTGAAACAGCTCCGGGG	MARK4	ENSG00000007047	-0.09148064484852321	[4]	[3,4]	-1	hSpCas9	positive selection	3745920
45271685	45271708	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.2278023195531918	[6]	[7,7]	6	hSpCas9	positive selection	3745921
45271601	45271624	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCAGGGCAAGAAGTACGACGG	MARK4	ENSG00000007047	-0.12835329861389788	[4]	[3,4]	-2	hSpCas9	positive selection	3745922
45264904	45264927	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCCCTGCCCCAACCTGTCGG	MARK4	ENSG00000007047	0.10600398627158661	[5]	[5,5]	2	hSpCas9	positive selection	3745923
45263325	45263348	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAGAAGTCCGCATCATGAAGGG	MARK4	ENSG00000007047	0.11967351928768272	[5]	[6,5]	3	hSpCas9	positive selection	3745924
45264856	45264879	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATGCGGCCATGCGACACGAGG	MARK4	ENSG00000007047	-0.030493245280511352	[5]	[4,4]	0	hSpCas9	positive selection	3854526
45271590	45271613	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGCCCTGAAACAGCTCCGGGG	MARK4	ENSG00000007047	-0.4414204550269586	[5]	[2,3]	-5	hSpCas9	positive selection	3854527
45271685	45271708	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.14884264253942525	[7]	[6,7]	3	hSpCas9	positive selection	3854528
45271601	45271624	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCAGGGCAAGAAGTACGACGG	MARK4	ENSG00000007047	0.20058973471728767	[4]	[4,4]	5	hSpCas9	positive selection	3854529
45264904	45264927	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCCCTGCCCCAACCTGTCGG	MARK4	ENSG00000007047	0.03683765056454891	[7]	[6,5]	0	hSpCas9	positive selection	3854530
45263325	45263348	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAGAAGTCCGCATCATGAAGGG	MARK4	ENSG00000007047	0.2473470816497687	[6]	[6,5]	6	hSpCas9	positive selection	3854531
45251578	45251601	19	+	26780180	A375	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.133105134242439	[]	[]	0	hSpCas9	negative selection	3960036
45263324	45263347	19	+	26780180	A375	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.701696072416246	[]	[]	2	hSpCas9	negative selection	3960037
45263150	45263173	19	-	26780180	A375	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	1.53016732518615	[]	[]	8	hSpCas9	negative selection	3960038
45263354	45263377	19	-	26780180	A375	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.632165660429018	[]	[]	2	hSpCas9	negative selection	3960039
45263145	45263168	19	+	26780180	A375	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	1.72132705387999	[]	[]	9	hSpCas9	negative selection	3960040
45251613	45251636	19	-	26780180	A375	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	2.00405843152914	[]	[]	9	hSpCas9	negative selection	3960041
45251578	45251601	19	+	26780180	HT29	viability (GeCKOv2 library)	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	1.23730206528547	[]	[]	6	hSpCas9	negative selection	4068002
45263324	45263347	19	+	26780180	HT29	viability (GeCKOv2 library)	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.724330086515676	[]	[]	2	hSpCas9	negative selection	4068003
45263150	45263173	19	-	26780180	HT29	viability (GeCKOv2 library)	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	1.37399742199077	[]	[]	7	hSpCas9	negative selection	4068004
45263354	45263377	19	-	26780180	HT29	viability (GeCKOv2 library)	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.955752213592454	[]	[]	4	hSpCas9	negative selection	4068005
45263145	45263168	19	+	26780180	HT29	viability (GeCKOv2 library)	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	2.01109090396824	[]	[]	9	hSpCas9	negative selection	4068006
45251613	45251636	19	-	26780180	HT29	viability (GeCKOv2 library)	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	2.4949418490651	[]	[]	9	hSpCas9	negative selection	4068007
45090306	45090329	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.016715300968097493	[3]	[2,2]	0	hSpCas9	positive selection	4139533
45090297	45090320	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.30705377153331376	[3]	[2,1]	-6	hSpCas9	positive selection	4139534
45251578	45251601	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	-0.09672766467376824	[3]	[3,1]	-2	hSpCas9	positive selection	4150772
45263117	45263140	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTTTTGTCGATAATCTTGATGG	MARK4	ENSG00000007047	-0.31689406232685857	[3]	[2,0]	-7	hSpCas9	positive selection	4150773
45251613	45251636	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.09337557615591313	[4]	[2,3]	2	hSpCas9	positive selection	4150774
45090306	45090329	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	0.2158487484646975	[4]	[0,0,0,3]	1	hSpCas9	positive selection	4203555
45090297	45090320	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.5476300397058721	[3]	[2,0,0,0]	-7	hSpCas9	positive selection	4203556
45251578	45251601	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.9404815662845742	[3]	[2,0,0,4]	6	hSpCas9	positive selection	4214794
45263117	45263140	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTTTTGTCGATAATCTTGATGG	MARK4	ENSG00000007047	0.9093565352700459	[2]	[4,3,4,0]	6	hSpCas9	positive selection	4214795
45251613	45251636	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.12093899992565132	[4]	[3,2,1,0]	-2	hSpCas9	positive selection	4214796
45090297	45090320	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.4650471065126948	[2]	[1,0]	-7	hSpCas9	positive selection	4272608
45090197	45090220	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.5642253179522132	[3]	[3,4]	9	hSpCas9	positive selection	4272609
45090306	45090329	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	0.1605436627350449	[3]	[3,2]	3	hSpCas9	positive selection	4272610
45251578	45251601	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.7787298316581529	[3]	[4,5]	9	hSpCas9	positive selection	4282032
45251613	45251636	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.6887818243775861	[3]	[2,0]	-9	hSpCas9	positive selection	4282033
45263324	45263347	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.08807703615562534	[1]	[1,0]	1	hSpCas9	positive selection	4282034
45090345	45090368	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.22371708889712494	[2]	[3,2]	4	hSpCas9	positive selection	4336872
45090329	45090352	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	0.4459475363155877	[2]	[2,3]	8	hSpCas9	positive selection	4336873
45090370	45090393	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	-0.22957001818298	[2]	[2,1]	-5	hSpCas9	positive selection	4336874
45263354	45263377	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.24997776319698606	[1]	[1,1]	5	hSpCas9	positive selection	4346290
45263150	45263173	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.34616852164078765	[3]	[3,4]	7	hSpCas9	positive selection	4346291
45263145	45263168	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.39982799700621624	[2]	[2,0]	-7	hSpCas9	positive selection	4346292
45259056	45259078	19	-	27760321	OCIAML3	viability	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.3551658343889103	[474,374]	[408,439]	4	hSpCas9	negative selection	4416933
45263352	45263374	19	+	27760321	OCIAML3	viability	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	0.3320611630476499	[516,449]	[496,445]	4	hSpCas9	negative selection	4416934
45264860	45264882	19	+	27760321	OCIAML3	viability	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	-0.2785023911940471	[646,590]	[368,437]	-3	hSpCas9	negative selection	4416935
45266221	45266243	19	-	27760321	OCIAML3	viability	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	-0.004383140318996115	[436,302]	[216,373]	0	hSpCas9	negative selection	4416936
45271688	45271710	19	+	27760321	OCIAML3	viability	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	-0.026204873774517745	[334,277]	[193,286]	0	hSpCas9	negative selection	4416937
45259056	45259078	19	-	27760321	OCIAML2	viability	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.05082402276326813	[474,374]	[289,437]	0	hSpCas9	negative selection	4500396
45263352	45263374	19	+	27760321	OCIAML2	viability	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	-0.1498391302530519	[516,449]	[415,266]	-2	hSpCas9	negative selection	4500397
45264860	45264882	19	+	27760321	OCIAML2	viability	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	0.2917866267253389	[646,590]	[547,697]	4	hSpCas9	negative selection	4500398
45266221	45266243	19	-	27760321	OCIAML2	viability	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	-0.2971750127246013	[436,302]	[210,279]	-4	hSpCas9	negative selection	4500399
45271688	45271710	19	+	27760321	OCIAML2	viability	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	0.24968721056598248	[334,277]	[280,309]	3	hSpCas9	negative selection	4500400
45259056	45259078	19	-	27760321	MV411	viability	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	-0.23660365111562293	[474,374]	[138,382]	-2	hSpCas9	negative selection	4583859
45263352	45263374	19	+	27760321	MV411	viability	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	-1.4685029436990087	[516,449]	[136,81]	-7	hSpCas9	negative selection	4583860
45264860	45264882	19	+	27760321	MV411	viability	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	-0.03844902313616094	[646,590]	[355,459]	0	hSpCas9	negative selection	4583861
45266221	45266243	19	-	27760321	MV411	viability	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	1.0688750711027137	[436,302]	[594,372]	7	hSpCas9	negative selection	4583862
45271688	45271710	19	+	27760321	MV411	viability	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	-0.03520271973489397	[334,277]	[106,330]	0	hSpCas9	negative selection	4583863
45259056	45259078	19	-	27760321	HL60	viability	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.2099281581741116	[474,374]	[348,451]	2	hSpCas9	negative selection	4667322
45263352	45263374	19	+	27760321	HL60	viability	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	0.455293598183995	[516,449]	[596,479]	5	hSpCas9	negative selection	4667323
45264860	45264882	19	+	27760321	HL60	viability	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	0.266638973634063	[646,590]	[691,518]	3	hSpCas9	negative selection	4667324
45266221	45266243	19	-	27760321	HL60	viability	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	-0.4058786978856859	[436,302]	[224,225]	-4	hSpCas9	negative selection	4667325
45271688	45271710	19	+	27760321	HL60	viability	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	-0.3374825579703088	[334,277]	[239,151]	-4	hSpCas9	negative selection	4667326
45259056	45259078	19	-	27760321	HT1080	viability	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.2692678170525606	[374,292]	[125,197]	1	hSpCas9	negative selection	4750785
45263352	45263374	19	+	27760321	HT1080	viability	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	0.32050251372557115	[449,350]	[182,216]	1	hSpCas9	negative selection	4750786
45264860	45264882	19	+	27760321	HT1080	viability	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	0.43358772116064315	[590,460]	[166,409]	2	hSpCas9	negative selection	4750787
45266221	45266243	19	-	27760321	HT1080	viability	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	0.5785028536138492	[302,236]	[131,191]	3	hSpCas9	negative selection	4750788
45271688	45271710	19	+	27760321	HT1080	viability	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	0.20003101573642013	[277,216]	[181,37]	1	hSpCas9	negative selection	4750789
45259056	45259078	19	-	27760321	HT29	viability after 7 days	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.36608143228712275	[374,292]	[627,509,532]	5	hSpCas9	negative selection	4834248
45263352	45263374	19	+	27760321	HT29	viability after 7 days	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	0.25309996874000373	[449,350]	[629,776,440]	4	hSpCas9	negative selection	4834249
45264860	45264882	19	+	27760321	HT29	viability after 7 days	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	-0.1921716117529973	[590,460]	[666,824,302]	-3	hSpCas9	negative selection	4834250
45266221	45266243	19	-	27760321	HT29	viability after 7 days	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	0.12204055963860955	[302,236]	[506,476,173]	1	hSpCas9	negative selection	4834251
45271688	45271710	19	+	27760321	HT29	viability after 7 days	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	0.06429754789728825	[277,216]	[472,253,291]	1	hSpCas9	negative selection	4834252
45259056	45259078	19	-	27760321	HT29	viability after 25 days	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.4869480115043632	[374,292]	[473,348,813]	5	hSpCas9	negative selection	4917711
45263352	45263374	19	+	27760321	HT29	viability after 25 days	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	0.2160410298136903	[449,350]	[434,470,712]	2	hSpCas9	negative selection	4917712
45264860	45264882	19	+	27760321	HT29	viability after 25 days	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	-0.19430284419214933	[590,460]	[638,335,600]	-2	hSpCas9	negative selection	4917713
45266221	45266243	19	-	27760321	HT29	viability after 25 days	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	0.24172464298710294	[302,236]	[596,302,157]	2	hSpCas9	negative selection	4917714
45271688	45271710	19	+	27760321	HT29	viability after 25 days	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	0.10778096953322353	[277,216]	[269,324,322]	1	hSpCas9	negative selection	4917715
45259056	45259078	19	-	27760321	HT29	viability after 22 days	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.43910140999924535	[374,292]	[282,461,834]	5	hSpCas9	negative selection	5001174
45263352	45263374	19	+	27760321	HT29	viability after 22 days	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	0.1707075077386537	[449,350]	[496,549,516]	1	hSpCas9	negative selection	5001175
45264860	45264882	19	+	27760321	HT29	viability after 22 days	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	-0.35945757148449986	[590,460]	[516,501,400]	-4	hSpCas9	negative selection	5001176
45266221	45266243	19	-	27760321	HT29	viability after 22 days	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	0.18570386332034833	[302,236]	[727,189,134]	1	hSpCas9	negative selection	5001177
45271688	45271710	19	+	27760321	HT29	viability after 22 days	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	-0.06414354991168936	[277,216]	[141,261,421]	0	hSpCas9	negative selection	5001178
45259056	45259078	19	-	27760321	HT29	viability after 19 days	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.1986738533293491	[374,292]	[467,195,645]	1	hSpCas9	negative selection	5084637
45263352	45263374	19	+	27760321	HT29	viability after 19 days	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	0.6506594061246355	[449,350]	[464,595,1055]	6	hSpCas9	negative selection	5084638
45264860	45264882	19	+	27760321	HT29	viability after 19 days	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	0.1572604765372897	[590,460]	[609,411,971]	1	hSpCas9	negative selection	5084639
45266221	45266243	19	-	27760321	HT29	viability after 19 days	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	0.8307041759168448	[302,236]	[333,689,598]	8	hSpCas9	negative selection	5084640
45271688	45271710	19	+	27760321	HT29	viability after 19 days	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	0.6490581232665379	[277,216]	[273,660,380]	6	hSpCas9	negative selection	5084641
45259056	45259078	19	-	27760321	HT29	viability after 16 days	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.4724608377637964	[374,292]	[590,452,519]	5	hSpCas9	negative selection	5168100
45263352	45263374	19	+	27760321	HT29	viability after 16 days	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	0.11971841209383252	[449,350]	[540,583,337]	1	hSpCas9	negative selection	5168101
45264860	45264882	19	+	27760321	HT29	viability after 16 days	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	-0.012216100410777253	[590,460]	[675,321,767]	0	hSpCas9	negative selection	5168102
45266221	45266243	19	-	27760321	HT29	viability after 16 days	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	0.24444014767689162	[302,236]	[500,363,221]	2	hSpCas9	negative selection	5168103
45271688	45271710	19	+	27760321	HT29	viability after 16 days	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	0.5535289695943401	[277,216]	[487,362,376]	6	hSpCas9	negative selection	5168104
45259056	45259078	19	-	27760321	HT29	viability after 13 days	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.7726565895428245	[374,292]	[679,628,675]	8	hSpCas9	negative selection	5251563
45263352	45263374	19	+	27760321	HT29	viability after 13 days	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	0.19657315506706877	[449,350]	[410,560,619]	2	hSpCas9	negative selection	5251564
45264860	45264882	19	+	27760321	HT29	viability after 13 days	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	0.1161271211432704	[590,460]	[693,852,449]	1	hSpCas9	negative selection	5251565
45266221	45266243	19	-	27760321	HT29	viability after 13 days	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	0.3906820675494199	[302,236]	[338,427,461]	5	hSpCas9	negative selection	5251566
45271688	45271710	19	+	27760321	HT29	viability after 13 days	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	0.3865547834412033	[277,216]	[275,453,394]	5	hSpCas9	negative selection	5251567
45259056	45259078	19	-	27760321	HT29	viability after 10 days	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.08449478710989716	[374,292]	[412,604,315]	1	hSpCas9	negative selection	5335026
45263352	45263374	19	+	27760321	HT29	viability after 10 days	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	-0.26111298044546	[449,350]	[391,334,519]	-3	hSpCas9	negative selection	5335027
45264860	45264882	19	+	27760321	HT29	viability after 10 days	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	0.14504480299035571	[590,460]	[655,548,962]	2	hSpCas9	negative selection	5335028
45266221	45266243	19	-	27760321	HT29	viability after 10 days	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	0.3027325446003225	[302,236]	[406,528,316]	4	hSpCas9	negative selection	5335029
45271688	45271710	19	+	27760321	HT29	viability after 10 days	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	0.34510624792398514	[277,216]	[367,432,377]	4	hSpCas9	negative selection	5335030
45259056	45259078	19	-	27760321	MOLM13	viability	GCGATGGAGTTCCGGCAACGGG	MARK4	ENSG00000007047	0.7630059642636768	[474,374]	[325,470]	5	hSpCas9	negative selection	5418489
45263352	45263374	19	+	27760321	MOLM13	viability	AACCACCCCAACATCGGTGAGG	MARK4	ENSG00000007047	-0.27968536519093523	[516,449]	[241,208]	-2	hSpCas9	negative selection	5418490
45264860	45264882	19	+	27760321	MOLM13	viability	GTGTCGCATGGCCGCATGAAGG	MARK4	ENSG00000007047	0.7078852722367972	[646,590]	[163,915]	5	hSpCas9	negative selection	5418491
45266221	45266243	19	-	27760321	MOLM13	viability	GTGCACAGCCGAAACAATCTGG	MARK4	ENSG00000007047	1.7117634876817778	[436,302]	[1107,307]	9	hSpCas9	negative selection	5418492
45271688	45271710	19	+	27760321	MOLM13	viability	TTCGACGGGCACAACCTCAAGG	MARK4	ENSG00000007047	0.045765588703018556	[334,277]	[167,185]	0	hSpCas9	negative selection	5418493
45079272	45079295	19	+	27661255	K562	viability	GGACCTCGGTGAGTACAAGGTGG	MARK4	ENSG00000007047	0.42952104628410803	[449,673]	[562,631]	9	dCas9-KRAB	negative selection	5481910
45079304	45079327	19	+	27661255	K562	viability	GCCAGCAGGTTCCCTCTCCCCGG	MARK4	ENSG00000007047	-0.19198835233420508	[556,637]	[520,327]	-6	dCas9-KRAB	negative selection	5481911
45079716	45079739	19	+	27661255	K562	viability	GTGGTCAGGGCGGAATTGAAAGG	MARK4	ENSG00000007047	0.04861627615830211	[1187,1227]	[1180,840]	1	dCas9-KRAB	negative selection	5481912
45251307	45251330	19	-	27661255	K562	viability	GGGCGCGGAGCCGGCCCAAGCGG	MARK4	ENSG00000007047	0.08946940516711455	[1602,1564]	[1551,1171]	3	dCas9-KRAB	negative selection	5492374
45251708	45251731	19	-	27661255	K562	viability	GTAGGGGCTCGCGGGGCGAGGGG	MARK4	ENSG00000007047	0.17273268110668755	[965,993]	[963,811]	6	dCas9-KRAB	negative selection	5492375
45251724	45251747	19	-	27661255	K562	viability	GGCCCAGGAAACGAGGGTAGGGG	MARK4	ENSG00000007047	0.19138255361854867	[531,625]	[572,486]	6	dCas9-KRAB	negative selection	5492376
45251745	45251768	19	-	27661255	K562	viability	GAGAGGTGACGAGCCGGGTCGGG	MARK4	ENSG00000007047	-0.013842476636122703	[146,266]	[167,156]	0	dCas9-KRAB	negative selection	5492377
45251762	45251785	19	-	27661255	K562	viability	GAAGTCCGGGAGGGGTCGAGAGG	MARK4	ENSG00000007047	-0.005729676308958043	[1883,1682]	[1605,1264]	0	dCas9-KRAB	negative selection	5492378
45251854	45251877	19	-	27661255	K562	viability	GGTCTGCACGGGGACAAGAGAGG	MARK4	ENSG00000007047	0.003832324564783801	[787,900]	[684,665]	0	dCas9-KRAB	negative selection	5492379
45090297	45090320	19	-	27260156	BXPC3	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.1426779055297832	[319]	[249,361,299,299]	-3	hSpCas9	negative selection	5545068
45090197	45090220	19	+	27260156	BXPC3	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.1331847208429991	[610]	[653,784,613,748]	3	hSpCas9	negative selection	5545069
45090306	45090329	19	+	27260156	BXPC3	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.18305226042147213	[564]	[453,417,564,673]	-4	hSpCas9	negative selection	5545070
45251578	45251601	19	+	27260156	BXPC3	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.4171920129585863	[668]	[696,767,1146,1188]	8	hSpCas9	negative selection	5554492
45251613	45251636	19	-	27260156	BXPC3	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.14178392502992054	[717]	[568,695,628,854]	-3	hSpCas9	negative selection	5554493
45263324	45263347	19	+	27260156	BXPC3	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.37299455360561184	[72]	[43,91,44,52]	-7	hSpCas9	negative selection	5554494
45090345	45090368	19	+	27260156	BXPC3	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.32672117677864876	[411]	[436,488,729,515]	7	hSpCas9	negative selection	5609332
45090329	45090352	19	-	27260156	BXPC3	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.7049605455747443	[400]	[190,236,336,273]	-8	hSpCas9	negative selection	5609333
45090370	45090393	19	+	27260156	BXPC3	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.4395966955737282	[359]	[442,496,449,675]	8	hSpCas9	negative selection	5609334
45263354	45263377	19	-	27260156	BXPC3	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.1046898894931001	[175]	[161,142,304,187]	2	hSpCas9	negative selection	5618750
45263150	45263173	19	-	27260156	BXPC3	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.192641959591891	[921]	[983,1094,1132,1214]	4	hSpCas9	negative selection	5618751
45263145	45263168	19	+	27260156	BXPC3	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.027400676642914096	[404]	[373,338,503,457]	0	hSpCas9	negative selection	5618752
45090297	45090320	19	-	27260156	A673	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.5351147813223072	[319]	[266,237,243,314]	-8	hSpCas9	negative selection	5666319
45090197	45090220	19	+	27260156	A673	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.031393023989904956	[610]	[830,749,671,754]	0	hSpCas9	negative selection	5666320
45090306	45090329	19	+	27260156	A673	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.39836373717237816	[564]	[481,527,493,551]	-7	hSpCas9	negative selection	5666321
45251578	45251601	19	+	27260156	A673	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.3675301600678834	[668]	[1052,980,1051,1061]	8	hSpCas9	negative selection	5675743
45251613	45251636	19	-	27260156	A673	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.10004320430332048	[717]	[773,942,757,729]	-2	hSpCas9	negative selection	5675744
45263324	45263347	19	+	27260156	A673	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.24055875211199584	[72]	[108,59,30,102]	-5	hSpCas9	negative selection	5675745
45090345	45090368	19	+	27260156	A673	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.24405964462056354	[411]	[700,505,563,586]	6	hSpCas9	negative selection	5730583
45090329	45090352	19	-	27260156	A673	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.33560011901319725	[400]	[300,304,526,383]	-7	hSpCas9	negative selection	5730584
45090370	45090393	19	+	27260156	A673	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.06626246740748909	[359]	[528,494,357,434]	1	hSpCas9	negative selection	5730585
45263354	45263377	19	-	27260156	A673	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.04065828111976044	[175]	[168,182,234,231]	-1	hSpCas9	negative selection	5740001
45263150	45263173	19	-	27260156	A673	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.19089518751147072	[921]	[1365,1209,1295,1188]	4	hSpCas9	negative selection	5740002
45263145	45263168	19	+	27260156	A673	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.2538101271868054	[404]	[392,433,353,449]	-6	hSpCas9	negative selection	5740003
45090297	45090320	19	-	27260156	A375	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.2300731404871286	[319]	[154,186,78,212]	-8	hSpCas9	negative selection	5787570
45090197	45090220	19	+	27260156	A375	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.08999916582203193	[610]	[781,655,660,588]	-1	hSpCas9	negative selection	5787571
45090306	45090329	19	+	27260156	A375	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.7327014815166863	[564]	[366,567,310,367]	-7	hSpCas9	negative selection	5787572
45251578	45251601	19	+	27260156	A375	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.530214384980471	[668]	[1271,1294,1054,934]	7	hSpCas9	negative selection	5796994
45251613	45251636	19	-	27260156	A375	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.0007912174833765162	[717]	[763,1106,739,781]	0	hSpCas9	negative selection	5796995
45263324	45263347	19	+	27260156	A375	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.19088638892936416	[72]	[111,144,62,77]	2	hSpCas9	negative selection	5796996
45090345	45090368	19	+	27260156	A375	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.5527201812088076	[411]	[658,1057,498,658]	7	hSpCas9	negative selection	5851834
45090329	45090352	19	-	27260156	A375	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.7990160744409871	[400]	[315,281,239,242]	-7	hSpCas9	negative selection	5851835
45090370	45090393	19	+	27260156	A375	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.1535448764183078	[359]	[535,410,533,389]	2	hSpCas9	negative selection	5851836
45263354	45263377	19	-	27260156	A375	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.034125085123992704	[175]	[222,220,144,248]	0	hSpCas9	negative selection	5861252
45263150	45263173	19	-	27260156	A375	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.3897503788672242	[921]	[1543,1859,1306,1035]	5	hSpCas9	negative selection	5861253
45263145	45263168	19	+	27260156	A375	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.014513060713711862	[404]	[507,437,448,471]	0	hSpCas9	negative selection	5861254
45090297	45090320	19	-	27260156	COLO741	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.25521812599137517	[319]	[373,374,284]	-5	hSpCas9	negative selection	5908821
45090197	45090220	19	+	27260156	COLO741	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.16943777494157536	[610]	[1032,792,822]	3	hSpCas9	negative selection	5908822
45090306	45090329	19	+	27260156	COLO741	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.15798636526553775	[564]	[650,767,529]	-3	hSpCas9	negative selection	5908823
45251578	45251601	19	+	27260156	COLO741	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.3349294258256851	[668]	[1061,1024,1138]	7	hSpCas9	negative selection	5918245
45251613	45251636	19	-	27260156	COLO741	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.003724538588035564	[717]	[1127,847,793]	0	hSpCas9	negative selection	5918246
45263324	45263347	19	+	27260156	COLO741	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.29014170024161023	[72]	[104,133,102]	6	hSpCas9	negative selection	5918247
45090345	45090368	19	+	27260156	COLO741	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.35422687225058336	[411]	[793,723,520]	7	hSpCas9	negative selection	5973085
45090329	45090352	19	-	27260156	COLO741	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.3352334163033192	[400]	[523,321,382]	-6	hSpCas9	negative selection	5973086
45090370	45090393	19	+	27260156	COLO741	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.2222925961713711	[359]	[586,589,442]	5	hSpCas9	negative selection	5973087
45263354	45263377	19	-	27260156	COLO741	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.45168972943455565	[175]	[252,280,377]	8	hSpCas9	negative selection	5982503
45263150	45263173	19	-	27260156	COLO741	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.16934471213882818	[921]	[1098,1463,1384]	3	hSpCas9	negative selection	5982504
45263145	45263168	19	+	27260156	COLO741	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.0471470497687797	[404]	[563,516,430]	-1	hSpCas9	negative selection	5982505
45090297	45090320	19	-	27260156	CAL120	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.698284485966091	[319]	[252,222,260]	-7	hSpCas9	negative selection	6030072
45090197	45090220	19	+	27260156	CAL120	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.16451975655270207	[610]	[912,895,757]	2	hSpCas9	negative selection	6030073
45090306	45090329	19	+	27260156	CAL120	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	0.007364676572677642	[564]	[819,621,694]	0	hSpCas9	negative selection	6030074
45251578	45251601	19	+	27260156	CAL120	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.46964537002596174	[668]	[1357,1210,923]	7	hSpCas9	negative selection	6039496
45251613	45251636	19	-	27260156	CAL120	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.058304019579404454	[717]	[823,1211,741]	0	hSpCas9	negative selection	6039497
45263324	45263347	19	+	27260156	CAL120	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	1.0378078574557827	[72]	[325,155,99]	9	hSpCas9	negative selection	6039498
45090345	45090368	19	+	27260156	CAL120	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.8583442982644686	[411]	[995,924,877]	9	hSpCas9	negative selection	6094336
45090329	45090352	19	-	27260156	CAL120	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.6509623234992505	[400]	[343,396,217]	-7	hSpCas9	negative selection	6094337
45090370	45090393	19	+	27260156	CAL120	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.1653853494555717	[359]	[568,445,501]	2	hSpCas9	negative selection	6094338
45263354	45263377	19	-	27260156	CAL120	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.2985830096790505	[175]	[224,176,396]	4	hSpCas9	negative selection	6103754
45263150	45263173	19	-	27260156	CAL120	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.32933327697145975	[921]	[1474,1968,894]	5	hSpCas9	negative selection	6103755
45263145	45263168	19	+	27260156	CAL120	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.06058688724315614	[404]	[573,548,461]	0	hSpCas9	negative selection	6103756
45090297	45090320	19	-	27260156	CADOES1	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.011721362437983	[319]	[138,137,150,162]	-9	hSpCas9	negative selection	6151323
45090197	45090220	19	+	27260156	CADOES1	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.17062948628942054	[610]	[580,403,429,607]	-3	hSpCas9	negative selection	6151324
45090306	45090329	19	+	27260156	CADOES1	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.34537677637828335	[564]	[451,337,403,461]	-6	hSpCas9	negative selection	6151325
45251578	45251601	19	+	27260156	CADOES1	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.8406348954748677	[668]	[1168,885,1374,1022]	9	hSpCas9	negative selection	6160747
45251613	45251636	19	-	27260156	CADOES1	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.10313820265277118	[717]	[682,652,764,769]	1	hSpCas9	negative selection	6160748
45263324	45263347	19	+	27260156	CADOES1	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.6176405146657933	[72]	[39,61,31,42]	-8	hSpCas9	negative selection	6160749
45090345	45090368	19	+	27260156	CADOES1	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.4379038617240647	[411]	[507,416,404,754]	7	hSpCas9	negative selection	6215587
45090329	45090352	19	-	27260156	CADOES1	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.7615505478218811	[400]	[181,179,245,273]	-8	hSpCas9	negative selection	6215588
45090370	45090393	19	+	27260156	CADOES1	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.2930377220289386	[359]	[277,364,437,565]	5	hSpCas9	negative selection	6215589
45263354	45263377	19	-	27260156	CADOES1	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.03193300221532924	[175]	[176,265,125,97]	0	hSpCas9	negative selection	6225005
45263150	45263173	19	-	27260156	CADOES1	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.329627976423566	[921]	[1061,1013,1166,1066]	5	hSpCas9	negative selection	6225006
45263145	45263168	19	+	27260156	CADOES1	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.42633025384232154	[404]	[233,275,185,430]	-6	hSpCas9	negative selection	6225007
45090297	45090320	19	-	27260156	EWS502	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.272777977472202	[319]	[93,175,120,175]	-9	hSpCas9	negative selection	6272574
45090197	45090220	19	+	27260156	EWS502	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.31251406303033386	[610]	[550,932,839,921]	5	hSpCas9	negative selection	6272575
45090306	45090329	19	+	27260156	EWS502	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.10193134417463581	[564]	[376,706,582,578]	-2	hSpCas9	negative selection	6272576
45251578	45251601	19	+	27260156	EWS502	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.3648434627324816	[668]	[821,824,968,1055]	6	hSpCas9	negative selection	6281998
45251613	45251636	19	-	27260156	EWS502	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.13343543659405127	[717]	[451,711,648,1007]	-2	hSpCas9	negative selection	6281999
45263324	45263347	19	+	27260156	EWS502	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.12677369673947325	[72]	[54,106,111,64]	2	hSpCas9	negative selection	6282000
45090345	45090368	19	+	27260156	EWS502	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.4120987496537297	[411]	[386,599,646,719]	7	hSpCas9	negative selection	6336838
45090329	45090352	19	-	27260156	EWS502	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.7052957753640379	[400]	[169,264,246,377]	-8	hSpCas9	negative selection	6336839
45090370	45090393	19	+	27260156	EWS502	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.4792274792965947	[359]	[459,526,504,648]	8	hSpCas9	negative selection	6336840
45263354	45263377	19	-	27260156	EWS502	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.1571005790887976	[175]	[177,186,244,226]	2	hSpCas9	negative selection	6346256
45263150	45263173	19	-	27260156	EWS502	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.12784535315727508	[921]	[932,1140,1189,1010]	2	hSpCas9	negative selection	6346257
45263145	45263168	19	+	27260156	EWS502	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.04508269457958142	[404]	[378,563,367,342]	-1	hSpCas9	negative selection	6346258
45090297	45090320	19	-	27260156	EW8	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.6147794099650494	[319]	[152,109,232,167]	-8	hSpCas9	negative selection	6393825
45090197	45090220	19	+	27260156	EW8	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.028766392656523643	[610]	[538,495,468,444]	0	hSpCas9	negative selection	6393826
45090306	45090329	19	+	27260156	EW8	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.5612133070180552	[564]	[316,306,292,326]	-7	hSpCas9	negative selection	6393827
45251578	45251601	19	+	27260156	EW8	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.16780310704352264	[668]	[538,739,503,661]	3	hSpCas9	negative selection	6403249
45251613	45251636	19	-	27260156	EW8	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.14417809371855844	[717]	[671,466,523,457]	-3	hSpCas9	negative selection	6403250
45263324	45263347	19	+	27260156	EW8	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.7162354482547553	[72]	[18,33,65,17]	-8	hSpCas9	negative selection	6403251
45090345	45090368	19	+	27260156	EW8	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.3062608632556229	[411]	[340,380,429,486]	5	hSpCas9	negative selection	6458089
45090329	45090352	19	-	27260156	EW8	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.21026746684437897	[400]	[222,379,256,260]	-4	hSpCas9	negative selection	6458090
45090370	45090393	19	+	27260156	EW8	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.24990772700482625	[359]	[387,304,364,329]	4	hSpCas9	negative selection	6458091
45263354	45263377	19	-	27260156	EW8	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.13832846872544646	[175]	[115,100,202,83]	-3	hSpCas9	negative selection	6467507
45263150	45263173	19	-	27260156	EW8	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.1786896585337051	[921]	[838,764,737,1054]	3	hSpCas9	negative selection	6467508
45263145	45263168	19	+	27260156	EW8	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.514220838818854	[404]	[235,199,229,252]	-7	hSpCas9	negative selection	6467509
45090297	45090320	19	-	27260156	CORL105	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.3828672693000903	[319]	[245,215,445,265]	-6	hSpCas9	negative selection	6515076
45090197	45090220	19	+	27260156	CORL105	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.02118579633192863	[610]	[686,819,767,631]	0	hSpCas9	negative selection	6515077
45090306	45090329	19	+	27260156	CORL105	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.47336069502324374	[564]	[513,453,486,453]	-7	hSpCas9	negative selection	6515078
45251578	45251601	19	+	27260156	CORL105	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.6347304220664634	[668]	[1257,1338,1263,1009]	9	hSpCas9	negative selection	6524500
45251613	45251636	19	-	27260156	CORL105	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.19205011324007892	[717]	[941,763,1241,939]	3	hSpCas9	negative selection	6524501
45263324	45263347	19	+	27260156	CORL105	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.3661319270018275	[72]	[65,43,112,49]	-6	hSpCas9	negative selection	6524502
45090345	45090368	19	+	27260156	CORL105	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.08014348076802588	[411]	[488,535,552,466]	1	hSpCas9	negative selection	6579340
45090329	45090352	19	-	27260156	CORL105	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-1.064097456775873	[400]	[189,143,399,191]	-9	hSpCas9	negative selection	6579341
45090370	45090393	19	+	27260156	CORL105	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.44591873624475853	[359]	[577,482,700,555]	7	hSpCas9	negative selection	6579342
45263354	45263377	19	-	27260156	CORL105	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.23890707934982314	[175]	[125,137,532,218]	4	hSpCas9	negative selection	6588758
45263150	45263173	19	-	27260156	CORL105	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.060886900714633874	[921]	[935,1025,1266,1290]	1	hSpCas9	negative selection	6588759
45263145	45263168	19	+	27260156	CORL105	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.0653834399321675	[404]	[420,541,604,265]	-1	hSpCas9	negative selection	6588760
45090297	45090320	19	-	27260156	HS294T	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.2025033562493568	[319]	[27,36,78,77]	-9	hSpCas9	negative selection	6636327
45090197	45090220	19	+	27260156	HS294T	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.15438782079619662	[610]	[142,194,238,291]	-2	hSpCas9	negative selection	6636328
45090306	45090329	19	+	27260156	HS294T	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.6278276355052483	[564]	[103,129,153,188]	-7	hSpCas9	negative selection	6636329
45251578	45251601	19	+	27260156	HS294T	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.4185877303451301	[668]	[275,325,397,397]	5	hSpCas9	negative selection	6645751
45251613	45251636	19	-	27260156	HS294T	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.11893182649493927	[717]	[203,343,202,493]	1	hSpCas9	negative selection	6645752
45263324	45263347	19	+	27260156	HS294T	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.7196084027623986	[72]	[26,7,19,11]	-8	hSpCas9	negative selection	6645753
45090345	45090368	19	+	27260156	HS294T	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.40266084947697667	[411]	[173,290,178,195]	5	hSpCas9	negative selection	6700591
45090329	45090352	19	-	27260156	HS294T	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.1247804738673618	[400]	[184,101,103,180]	-2	hSpCas9	negative selection	6700592
45090370	45090393	19	+	27260156	HS294T	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.4092419640497125	[359]	[139,242,168,189]	5	hSpCas9	negative selection	6700593
45263354	45263377	19	-	27260156	HS294T	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.6147409533852676	[175]	[55,199,56,104]	7	hSpCas9	negative selection	6710009
45263150	45263173	19	-	27260156	HS294T	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	-0.24537226233635268	[921]	[270,359,244,331]	-3	hSpCas9	negative selection	6710010
45263145	45263168	19	+	27260156	HS294T	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.4092233099598065	[404]	[130,254,217,237]	5	hSpCas9	negative selection	6710011
45090297	45090320	19	-	27260156	HCC44	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.2838689209397434	[319]	[272,27,167,155]	-9	hSpCas9	negative selection	6757578
45090197	45090220	19	+	27260156	HCC44	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.7101948739125945	[610]	[1443,1096,926,1045]	9	hSpCas9	negative selection	6757579
45090306	45090329	19	+	27260156	HCC44	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.028498100733230863	[564]	[479,442,978,670]	0	hSpCas9	negative selection	6757580
45251578	45251601	19	+	27260156	HCC44	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.8865865280290126	[668]	[1281,1017,1426,1888]	9	hSpCas9	negative selection	6767002
45251613	45251636	19	-	27260156	HCC44	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.13165446740492082	[717]	[1111,630,1101,802]	2	hSpCas9	negative selection	6767003
45263324	45263347	19	+	27260156	HCC44	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.9153002428779831	[72]	[152,74,241,176]	9	hSpCas9	negative selection	6767004
45090345	45090368	19	+	27260156	HCC44	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.6318563127204475	[411]	[879,378,1264,521]	9	hSpCas9	negative selection	6821842
45090329	45090352	19	-	27260156	HCC44	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.9111343351336014	[400]	[407,175,191,203]	-8	hSpCas9	negative selection	6821843
45090370	45090393	19	+	27260156	HCC44	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.22950898158774352	[359]	[454,359,590,531]	3	hSpCas9	negative selection	6821844
45263354	45263377	19	-	27260156	HCC44	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.16205976158957225	[175]	[206,231,192,78]	-3	hSpCas9	negative selection	6831260
45263150	45263173	19	-	27260156	HCC44	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.0801573038693596	[921]	[1199,864,1420,1014]	1	hSpCas9	negative selection	6831261
45263145	45263168	19	+	27260156	HCC44	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.07487212750540814	[404]	[476,400,487,568]	1	hSpCas9	negative selection	6831262
45090297	45090320	19	-	27260156	G402	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.8812906468248578	[319]	[234,187,234,191]	-8	hSpCas9	negative selection	6878829
45090197	45090220	19	+	27260156	G402	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.4546557286930869	[610]	[794,617,310,492]	-5	hSpCas9	negative selection	6878830
45090306	45090329	19	+	27260156	G402	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.31918596715367464	[564]	[749,192,745,527]	-4	hSpCas9	negative selection	6878831
45251578	45251601	19	+	27260156	G402	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.4940669931904207	[668]	[1430,1177,991,1040]	6	hSpCas9	negative selection	6888253
45251613	45251636	19	-	27260156	G402	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.12493885278292172	[717]	[1072,790,832,1119]	1	hSpCas9	negative selection	6888254
45263324	45263347	19	+	27260156	G402	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.13387129241529117	[72]	[106,46,222,15]	1	hSpCas9	negative selection	6888255
45090345	45090368	19	+	27260156	G402	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.4319382767105444	[411]	[688,592,666,753]	5	hSpCas9	negative selection	6943093
45090329	45090352	19	-	27260156	G402	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-1.6360400194952518	[400]	[125,208,80,208]	-9	hSpCas9	negative selection	6943094
45090370	45090393	19	+	27260156	G402	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.6088777425491384	[359]	[772,497,571,830]	7	hSpCas9	negative selection	6943095
45263354	45263377	19	-	27260156	G402	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.38870924833841447	[175]	[243,103,160,154]	-5	hSpCas9	negative selection	6952511
45263150	45263173	19	-	27260156	G402	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.1003887377530478	[921]	[1514,1579,901,903]	1	hSpCas9	negative selection	6952512
45263145	45263168	19	+	27260156	G402	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.27340497595394875	[404]	[374,534,352,374]	-3	hSpCas9	negative selection	6952513
45090297	45090320	19	-	27260156	L33	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.3485300055611962	[319]	[246,89,157,286]	-7	hSpCas9	negative selection	7000080
45090197	45090220	19	+	27260156	L33	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.45723038492591356	[610]	[697,388,462,972]	8	hSpCas9	negative selection	7000081
45090306	45090329	19	+	27260156	L33	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	0.07033445419589496	[564]	[592,237,371,606]	1	hSpCas9	negative selection	7000082
45251578	45251601	19	+	27260156	L33	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.5878937987415551	[668]	[967,425,671,946]	9	hSpCas9	negative selection	7009504
45251613	45251636	19	-	27260156	L33	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.032117632474189195	[717]	[665,262,435,806]	0	hSpCas9	negative selection	7009505
45263324	45263347	19	+	27260156	L33	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.6253786246829676	[72]	[49,15,42,31]	-9	hSpCas9	negative selection	7009506
45090345	45090368	19	+	27260156	L33	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.2539994544944489	[411]	[612,183,312,402]	5	hSpCas9	negative selection	7064344
45090329	45090352	19	-	27260156	L33	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.2531241246257955	[400]	[301,119,230,383]	-5	hSpCas9	negative selection	7064345
45090370	45090393	19	+	27260156	L33	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.4628745947529977	[359]	[366,235,304,558]	8	hSpCas9	negative selection	7064346
45263354	45263377	19	-	27260156	L33	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.16465985682791207	[175]	[208,71,126,201]	3	hSpCas9	negative selection	7073762
45263150	45263173	19	-	27260156	L33	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	-0.3558597984021685	[921]	[676,293,461,752]	-7	hSpCas9	negative selection	7073763
45263145	45263168	19	+	27260156	L33	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.27023595520317867	[404]	[518,183,289,522]	6	hSpCas9	negative selection	7073764
45090297	45090320	19	-	27260156	K562	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.5006235864538893	[319]	[142,404,162,107]	-6	hSpCas9	negative selection	7121331
45090197	45090220	19	+	27260156	K562	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.174652395998285	[610]	[602,497,485,357]	-2	hSpCas9	negative selection	7121332
45090306	45090329	19	+	27260156	K562	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	0.25355845794989806	[564]	[621,681,626,477]	3	hSpCas9	negative selection	7121333
45251578	45251601	19	+	27260156	K562	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.1727784875556282	[668]	[959,665,565,522]	2	hSpCas9	negative selection	7130755
45251613	45251636	19	-	27260156	K562	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.06839026008914262	[717]	[776,784,410,706]	0	hSpCas9	negative selection	7130756
45263324	45263347	19	+	27260156	K562	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-1.0253454629677337	[72]	[9,11,104,0]	-8	hSpCas9	negative selection	7130757
45090345	45090368	19	+	27260156	K562	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.5404946327159089	[411]	[796,525,354,474]	7	hSpCas9	negative selection	7185595
45090329	45090352	19	-	27260156	K562	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.6139914411600145	[400]	[76,306,159,360]	-6	hSpCas9	negative selection	7185596
45090370	45090393	19	+	27260156	K562	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.2595264178948937	[359]	[403,195,649,281]	3	hSpCas9	negative selection	7185597
45263354	45263377	19	-	27260156	K562	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.3893370529121929	[175]	[66,247,129,42]	-5	hSpCas9	negative selection	7195013
45263150	45263173	19	-	27260156	K562	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.18948517037053592	[921]	[790,1330,743,877]	2	hSpCas9	negative selection	7195014
45263145	45263168	19	+	27260156	K562	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.10097237830664417	[404]	[468,215,371,470]	1	hSpCas9	negative selection	7195015
45090297	45090320	19	-	27260156	HT29	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.0637136054607186	[319]	[215,145,158,216]	-9	hSpCas9	negative selection	7242582
45090197	45090220	19	+	27260156	HT29	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.10361178598280651	[610]	[613,901,706,564]	-2	hSpCas9	negative selection	7242583
45090306	45090329	19	+	27260156	HT29	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.18369220501898714	[564]	[663,782,442,550]	-4	hSpCas9	negative selection	7242584
45251578	45251601	19	+	27260156	HT29	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.2066565509379914	[668]	[936,889,924,984]	4	hSpCas9	negative selection	7252006
45251613	45251636	19	-	27260156	HT29	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.04838856121846902	[717]	[907,1042,839,627]	-1	hSpCas9	negative selection	7252007
45263324	45263347	19	+	27260156	HT29	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.4602233914017262	[72]	[52,64,49,85]	-7	hSpCas9	negative selection	7252008
45090345	45090368	19	+	27260156	HT29	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.3808252362247133	[411]	[613,653,707,627]	7	hSpCas9	negative selection	7306846
45090329	45090352	19	-	27260156	HT29	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.8001615749077258	[400]	[335,251,263,268]	-8	hSpCas9	negative selection	7306847
45090370	45090393	19	+	27260156	HT29	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.060458047869368314	[359]	[548,474,477,342]	1	hSpCas9	negative selection	7306848
45263354	45263377	19	-	27260156	HT29	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.00913099040995391	[175]	[169,230,303,149]	0	hSpCas9	negative selection	7316264
45263150	45263173	19	-	27260156	HT29	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.1832056041057647	[921]	[1428,1445,1248,1015]	3	hSpCas9	negative selection	7316265
45263145	45263168	19	+	27260156	HT29	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.38906163479701855	[404]	[391,494,271,355]	-6	hSpCas9	negative selection	7316266
45090297	45090320	19	-	27260156	MHHES1	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.7998036262144941	[319]	[377,117,184,163]	-9	hSpCas9	negative selection	7363833
45090197	45090220	19	+	27260156	MHHES1	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.2538973531022476	[610]	[673,792,481,416]	-5	hSpCas9	negative selection	7363834
45090306	45090329	19	+	27260156	MHHES1	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.7170603731015772	[564]	[378,540,275,362]	-8	hSpCas9	negative selection	7363835
45251578	45251601	19	+	27260156	MHHES1	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.43058461774954015	[668]	[1191,1071,936,892]	7	hSpCas9	negative selection	7373257
45251613	45251636	19	-	27260156	MHHES1	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.03609185257277314	[717]	[758,994,924,665]	0	hSpCas9	negative selection	7373258
45263324	45263347	19	+	27260156	MHHES1	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.5908524849523524	[72]	[102,72,6,43]	-8	hSpCas9	negative selection	7373259
45090345	45090368	19	+	27260156	MHHES1	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	-0.08310384522414832	[411]	[299,511,679,279]	-1	hSpCas9	negative selection	7428097
45090329	45090352	19	-	27260156	MHHES1	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.7047244494280349	[400]	[242,306,304,251]	-8	hSpCas9	negative selection	7428098
45090370	45090393	19	+	27260156	MHHES1	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.03815694603000014	[359]	[519,328,534,302]	0	hSpCas9	negative selection	7428099
45263354	45263377	19	-	27260156	MHHES1	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.14642870878691583	[175]	[270,293,214,127]	2	hSpCas9	negative selection	7437515
45263150	45263173	19	-	27260156	MHHES1	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.08077674267462431	[921]	[1328,1034,1382,730]	1	hSpCas9	negative selection	7437516
45263145	45263168	19	+	27260156	MHHES1	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.19221683016524438	[404]	[650,179,326,429]	-4	hSpCas9	negative selection	7437517
45090297	45090320	19	-	27260156	MEWO	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.496147594124952	[319]	[207,192,234]	-8	hSpCas9	negative selection	7485084
45090197	45090220	19	+	27260156	MEWO	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.027552437458473855	[610]	[634,574,547]	0	hSpCas9	negative selection	7485085
45090306	45090329	19	+	27260156	MEWO	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.03309529139976833	[564]	[451,553,530]	0	hSpCas9	negative selection	7485086
45251578	45251601	19	+	27260156	MEWO	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.36281797576440555	[668]	[997,559,894]	7	hSpCas9	negative selection	7494508
45251613	45251636	19	-	27260156	MEWO	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.09037914572014383	[717]	[751,454,709]	-2	hSpCas9	negative selection	7494509
45263324	45263347	19	+	27260156	MEWO	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.3200376056310148	[72]	[126,52,83]	6	hSpCas9	negative selection	7494510
45090345	45090368	19	+	27260156	MEWO	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.307563004934352	[411]	[577,389,482]	6	hSpCas9	negative selection	7549348
45090329	45090352	19	-	27260156	MEWO	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.3515877630474937	[400]	[299,325,256]	-6	hSpCas9	negative selection	7549349
45090370	45090393	19	+	27260156	MEWO	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.2888654930236187	[359]	[515,319,418]	6	hSpCas9	negative selection	7549350
45263354	45263377	19	-	27260156	MEWO	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.36068932487688454	[175]	[218,150,265]	7	hSpCas9	negative selection	7558766
45263150	45263173	19	-	27260156	MEWO	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.07253008579349884	[921]	[1070,854,826]	1	hSpCas9	negative selection	7558767
45263145	45263168	19	+	27260156	MEWO	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.07716925641060823	[404]	[454,356,283]	-2	hSpCas9	negative selection	7558768
45090297	45090320	19	-	27260156	LNCAPCLONEFGC	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.49562957635926774	[319]	[135,210,230,248]	-6	hSpCas9	negative selection	7606335
45090197	45090220	19	+	27260156	LNCAPCLONEFGC	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.45444945510554086	[610]	[401,269,630,354]	-6	hSpCas9	negative selection	7606336
45090306	45090329	19	+	27260156	LNCAPCLONEFGC	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.6989202010956428	[564]	[334,277,368,288]	-8	hSpCas9	negative selection	7606337
45251578	45251601	19	+	27260156	LNCAPCLONEFGC	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.7738894982936539	[668]	[952,862,1182,1179]	9	hSpCas9	negative selection	7615759
45251613	45251636	19	-	27260156	LNCAPCLONEFGC	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.11593963186170558	[717]	[730,352,686,655]	-2	hSpCas9	negative selection	7615760
45263324	45263347	19	+	27260156	LNCAPCLONEFGC	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.7557018886341302	[72]	[120,124,94,101]	9	hSpCas9	negative selection	7615761
45090345	45090368	19	+	27260156	LNCAPCLONEFGC	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.47822798646390774	[411]	[552,402,510,617]	7	hSpCas9	negative selection	7670599
45090329	45090352	19	-	27260156	LNCAPCLONEFGC	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.5088643917059636	[400]	[312,211,162,320]	-7	hSpCas9	negative selection	7670600
45090370	45090393	19	+	27260156	LNCAPCLONEFGC	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.4159697110324824	[359]	[403,450,531,366]	6	hSpCas9	negative selection	7670601
45263354	45263377	19	-	27260156	LNCAPCLONEFGC	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.17960520996601725	[175]	[207,212,136,154]	3	hSpCas9	negative selection	7680017
45263150	45263173	19	-	27260156	LNCAPCLONEFGC	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.27063848283821346	[921]	[1132,775,1065,1075]	4	hSpCas9	negative selection	7680018
45263145	45263168	19	+	27260156	LNCAPCLONEFGC	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.10314245094678574	[404]	[352,242,489,514]	1	hSpCas9	negative selection	7680019
45090297	45090320	19	-	27260156	PANC0327	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.9421715302314422	[319]	[28,113,69,73]	-9	hSpCas9	negative selection	7727586
45090197	45090220	19	+	27260156	PANC0327	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.1664891732549098	[610]	[480,397,641,931]	2	hSpCas9	negative selection	7727587
45090306	45090329	19	+	27260156	PANC0327	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.750388804946841	[564]	[526,243,228,218]	-8	hSpCas9	negative selection	7727588
45251578	45251601	19	+	27260156	PANC0327	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.4315441638162839	[668]	[812,495,1278,658]	6	hSpCas9	negative selection	7737010
45251613	45251636	19	-	27260156	PANC0327	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.5987463433715206	[717]	[640,541,1455,1252]	8	hSpCas9	negative selection	7737011
45263324	45263347	19	+	27260156	PANC0327	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.3871678877479945	[72]	[43,76,153,61]	6	hSpCas9	negative selection	7737012
45090345	45090368	19	+	27260156	PANC0327	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.534506985810218	[411]	[405,422,630,663]	7	hSpCas9	negative selection	7791850
45090329	45090352	19	-	27260156	PANC0327	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	0.08753835747607505	[400]	[343,285,426,465]	1	hSpCas9	negative selection	7791851
45090370	45090393	19	+	27260156	PANC0327	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	-0.10320426864006016	[359]	[338,126,261,487]	-1	hSpCas9	negative selection	7791852
45263354	45263377	19	-	27260156	PANC0327	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.3586931703469123	[175]	[221,119,43,109]	-5	hSpCas9	negative selection	7801268
45263150	45263173	19	-	27260156	PANC0327	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.2759913313320309	[921]	[1360,739,875,1051]	4	hSpCas9	negative selection	7801269
45263145	45263168	19	+	27260156	PANC0327	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.4359222152394417	[404]	[357,244,267,202]	-6	hSpCas9	negative selection	7801270
45090297	45090320	19	-	27260156	NCIH2009	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.7471231328774086	[319]	[127,94,175]	-9	hSpCas9	negative selection	7848837
45090197	45090220	19	+	27260156	NCIH2009	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.10461497623080829	[610]	[1059,924,794]	1	hSpCas9	negative selection	7848838
45090306	45090329	19	+	27260156	NCIH2009	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.0852674724553063	[564]	[891,481,890]	-1	hSpCas9	negative selection	7848839
45251578	45251601	19	+	27260156	NCIH2009	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.5726531876456851	[668]	[1708,1338,1183]	7	hSpCas9	negative selection	7858261
45251613	45251636	19	-	27260156	NCIH2009	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.06010417019432679	[717]	[1019,656,1224]	-1	hSpCas9	negative selection	7858262
45263324	45263347	19	+	27260156	NCIH2009	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-1.23416174406923	[72]	[59,58,13]	-8	hSpCas9	negative selection	7858263
45090345	45090368	19	+	27260156	NCIH2009	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.02604259991469207	[411]	[793,499,505]	0	hSpCas9	negative selection	7913101
45090329	45090352	19	-	27260156	NCIH2009	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-1.3381974139070176	[400]	[252,309,105]	-8	hSpCas9	negative selection	7913102
45090370	45090393	19	+	27260156	NCIH2009	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.758479603687348	[359]	[1002,425,1159]	9	hSpCas9	negative selection	7913103
45263354	45263377	19	-	27260156	NCIH2009	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.2772214902335228	[175]	[336,196,100]	-4	hSpCas9	negative selection	7922519
45263150	45263173	19	-	27260156	NCIH2009	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.059414342247042895	[921]	[1610,1167,1301]	0	hSpCas9	negative selection	7922520
45263145	45263168	19	+	27260156	NCIH2009	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.014435902223260993	[404]	[625,483,615]	0	hSpCas9	negative selection	7922521
45090297	45090320	19	-	27260156	NCIH1373	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.9378953815438902	[319]	[112,73,138,12]	-9	hSpCas9	negative selection	7970088
45090197	45090220	19	+	27260156	NCIH1373	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.3175221532085184	[610]	[354,402,601,219]	-3	hSpCas9	negative selection	7970089
45090306	45090329	19	+	27260156	NCIH1373	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.6030747896617745	[564]	[480,464,342,99]	-5	hSpCas9	negative selection	7970090
45251578	45251601	19	+	27260156	NCIH1373	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.8273201968193487	[668]	[2103,1343,902,282]	8	hSpCas9	negative selection	7979512
45251613	45251636	19	-	27260156	NCIH1373	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.6446228114659784	[717]	[1489,1311,796,388]	6	hSpCas9	negative selection	7979513
45263324	45263347	19	+	27260156	NCIH1373	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-1.1113456577473984	[72]	[23,64,1,14]	-8	hSpCas9	negative selection	7979514
45090345	45090368	19	+	27260156	NCIH1373	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.02858853944634998	[411]	[368,419,526,146]	0	hSpCas9	negative selection	8034352
45090329	45090352	19	-	27260156	NCIH1373	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.9789422165731136	[400]	[210,287,318,18]	-7	hSpCas9	negative selection	8034353
45090370	45090393	19	+	27260156	NCIH1373	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.03776959644291722	[359]	[513,213,563,103]	0	hSpCas9	negative selection	8034354
45263354	45263377	19	-	27260156	NCIH1373	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.04416311909362913	[175]	[91,198,180,73]	0	hSpCas9	negative selection	8043770
45263150	45263173	19	-	27260156	NCIH1373	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.12932362883625348	[921]	[1484,802,1172,300]	1	hSpCas9	negative selection	8043771
45263145	45263168	19	+	27260156	NCIH1373	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.5261506055837069	[404]	[339,543,134,56]	-5	hSpCas9	negative selection	8043772
45090297	45090320	19	-	27260156	PATU8902	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.5958988599681512	[319]	[151,334,58,54]	-8	hSpCas9	negative selection	8091339
45090197	45090220	19	+	27260156	PATU8902	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.2031070369865826	[610]	[1031,548,432,1048]	-2	hSpCas9	negative selection	8091340
45090306	45090329	19	+	27260156	PATU8902	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-1.053138387781487	[564]	[250,472,205,664]	-7	hSpCas9	negative selection	8091341
45251578	45251601	19	+	27260156	PATU8902	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.4717418476814277	[668]	[1415,1179,954,1746]	5	hSpCas9	negative selection	8100763
45251613	45251636	19	-	27260156	PATU8902	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.08922277759486663	[717]	[1098,943,675,1703]	0	hSpCas9	negative selection	8100764
45263324	45263347	19	+	27260156	PATU8902	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.6708640460627557	[72]	[48,4,160,7]	-6	hSpCas9	negative selection	8100765
45090345	45090368	19	+	27260156	PATU8902	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.25699345104789806	[411]	[508,1166,398,747]	2	hSpCas9	negative selection	8155603
45090329	45090352	19	-	27260156	PATU8902	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-1.6097420156168611	[400]	[236,26,91,425]	-8	hSpCas9	negative selection	8155604
45090370	45090393	19	+	27260156	PATU8902	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.7963750335634112	[359]	[1385,581,727,800]	8	hSpCas9	negative selection	8155605
45263354	45263377	19	-	27260156	PATU8902	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.2886581748804873	[175]	[468,213,265,245]	3	hSpCas9	negative selection	8165021
45263150	45263173	19	-	27260156	PATU8902	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.3110870683573729	[921]	[1969,1447,1541,1381]	3	hSpCas9	negative selection	8165022
45263145	45263168	19	+	27260156	PATU8902	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.029040602075001976	[404]	[582,597,479,565]	0	hSpCas9	negative selection	8165023
45090297	45090320	19	-	27260156	PANC1	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.8720282391568446	[319]	[89,60,70,73]	-9	hSpCas9	negative selection	8212590
45090197	45090220	19	+	27260156	PANC1	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.36883834456674264	[610]	[489,811,965,495]	6	hSpCas9	negative selection	8212591
45090306	45090329	19	+	27260156	PANC1	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-1.1521285383226665	[564]	[248,317,105,215]	-8	hSpCas9	negative selection	8212592
45251578	45251601	19	+	27260156	PANC1	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.7071892943602625	[668]	[922,1338,935,666]	9	hSpCas9	negative selection	8222014
45251613	45251636	19	-	27260156	PANC1	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.054013709610376215	[717]	[674,541,814,518]	0	hSpCas9	negative selection	8222015
45263324	45263347	19	+	27260156	PANC1	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.5180205191414271	[72]	[53,83,59,148]	8	hSpCas9	negative selection	8222016
45090345	45090368	19	+	27260156	PANC1	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.14634381120876805	[411]	[227,517,451,391]	2	hSpCas9	negative selection	8276854
45090329	45090352	19	-	27260156	PANC1	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.9897960981127263	[400]	[231,142,167,144]	-8	hSpCas9	negative selection	8276855
45090370	45090393	19	+	27260156	PANC1	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.36023109751445487	[359]	[406,511,429,275]	6	hSpCas9	negative selection	8276856
45263354	45263377	19	-	27260156	PANC1	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.06521251591763089	[175]	[100,209,141,137]	-1	hSpCas9	negative selection	8286272
45263150	45263173	19	-	27260156	PANC1	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.012604635199469416	[921]	[942,831,629,781]	0	hSpCas9	negative selection	8286273
45263145	45263168	19	+	27260156	PANC1	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.22526266772303022	[404]	[348,209,327,281]	-4	hSpCas9	negative selection	8286274
45090297	45090320	19	-	27260156	PANC0813	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.1504554813289436	[319]	[118,211,199,142]	-9	hSpCas9	negative selection	8333841
45090197	45090220	19	+	27260156	PANC0813	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.2858407519041403	[610]	[623,469,715,549]	-4	hSpCas9	negative selection	8333842
45090306	45090329	19	+	27260156	PANC0813	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.7959653274052091	[564]	[260,420,410,421]	-8	hSpCas9	negative selection	8333843
45251578	45251601	19	+	27260156	PANC0813	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.7788211058803305	[668]	[1617,1604,992,1205]	9	hSpCas9	negative selection	8343265
45251613	45251636	19	-	27260156	PANC0813	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.015964858517504288	[717]	[713,789,1335,574]	0	hSpCas9	negative selection	8343266
45263324	45263347	19	+	27260156	PANC0813	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.7230910923439229	[72]	[62,79,38,27]	-8	hSpCas9	negative selection	8343267
45090345	45090368	19	+	27260156	PANC0813	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.14753206554322562	[411]	[400,724,546,461]	2	hSpCas9	negative selection	8398105
45090329	45090352	19	-	27260156	PANC0813	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-1.2816798912903693	[400]	[287,196,276,30]	-9	hSpCas9	negative selection	8398106
45090370	45090393	19	+	27260156	PANC0813	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.0467312431238614	[359]	[622,336,462,345]	0	hSpCas9	negative selection	8398107
45263354	45263377	19	-	27260156	PANC0813	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.5310936791380878	[175]	[145,213,121,92]	-7	hSpCas9	negative selection	8407523
45263150	45263173	19	-	27260156	PANC0813	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.16954523658362686	[921]	[1434,1292,1080,1087]	2	hSpCas9	negative selection	8407524
45263145	45263168	19	+	27260156	PANC0813	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.2610364404572995	[404]	[343,278,506,449]	-4	hSpCas9	negative selection	8407525
45090297	45090320	19	-	27260156	RDES	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.4817243104028226	[319]	[259,211,259,328]	-7	hSpCas9	negative selection	8455092
45090197	45090220	19	+	27260156	RDES	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.2914741924296496	[610]	[736,940,703,1075]	5	hSpCas9	negative selection	8455093
45090306	45090329	19	+	27260156	RDES	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.06953591962439432	[564]	[441,656,616,805]	-1	hSpCas9	negative selection	8455094
45251578	45251601	19	+	27260156	RDES	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.5993057336568057	[668]	[936,1053,1302,1440]	8	hSpCas9	negative selection	8464516
45251613	45251636	19	-	27260156	RDES	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.11486817204385891	[717]	[692,648,1143,1186]	1	hSpCas9	negative selection	8464517
45263324	45263347	19	+	27260156	RDES	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.07084016457657771	[72]	[54,60,136,112]	1	hSpCas9	negative selection	8464518
45090345	45090368	19	+	27260156	RDES	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.650339031030676	[411]	[536,812,805,853]	9	hSpCas9	negative selection	8519356
45090329	45090352	19	-	27260156	RDES	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.37218535952423354	[400]	[277,268,386,534]	-6	hSpCas9	negative selection	8519357
45090370	45090393	19	+	27260156	RDES	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.4503853875072752	[359]	[547,503,684,512]	7	hSpCas9	negative selection	8519358
45263354	45263377	19	-	27260156	RDES	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.04690476570397717	[175]	[210,214,201,197]	0	hSpCas9	negative selection	8528774
45263150	45263173	19	-	27260156	RDES	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.43745878695165696	[921]	[1162,1365,1382,1926]	7	hSpCas9	negative selection	8528775
45263145	45263168	19	+	27260156	RDES	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.06685324160386658	[404]	[420,432,398,527]	-1	hSpCas9	negative selection	8528776
45090297	45090320	19	-	27260156	PC3	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.47178916557909667	[319]	[131,179,512,230]	-8	hSpCas9	negative selection	8576343
45090197	45090220	19	+	27260156	PC3	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.22555987449871556	[610]	[332,624,1502,818]	5	hSpCas9	negative selection	8576344
45090306	45090329	19	+	27260156	PC3	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	0.06301432998136658	[564]	[389,388,1239,629]	1	hSpCas9	negative selection	8576345
45251578	45251601	19	+	27260156	PC3	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.370575018827778	[668]	[486,933,1246,1019]	7	hSpCas9	negative selection	8585767
45251613	45251636	19	-	27260156	PC3	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.1772696543728342	[717]	[426,564,961,738]	-4	hSpCas9	negative selection	8585768
45263324	45263347	19	+	27260156	PC3	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	0.6534004939021347	[72]	[42,163,277,54]	9	hSpCas9	negative selection	8585769
45090345	45090368	19	+	27260156	PC3	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.2980016136902683	[411]	[352,593,602,513]	6	hSpCas9	negative selection	8640607
45090329	45090352	19	-	27260156	PC3	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-1.038015959786021	[400]	[110,205,378,171]	-9	hSpCas9	negative selection	8640608
45090370	45090393	19	+	27260156	PC3	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.06402671857442555	[359]	[218,338,611,462]	1	hSpCas9	negative selection	8640609
45263354	45263377	19	-	27260156	PC3	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.2667144194114641	[175]	[126,158,211,96]	-6	hSpCas9	negative selection	8650025
45263150	45263173	19	-	27260156	PC3	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.10502532786896224	[921]	[717,926,1567,977]	2	hSpCas9	negative selection	8650026
45263145	45263168	19	+	27260156	PC3	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.038122446640857954	[404]	[264,271,903,442]	0	hSpCas9	negative selection	8650027
45090297	45090320	19	-	27260156	PATU8988T	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.3866936793257045	[319]	[96,250,37,98]	-9	hSpCas9	negative selection	8697594
45090197	45090220	19	+	27260156	PATU8988T	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.1547100354337994	[610]	[289,716,481,660]	-3	hSpCas9	negative selection	8697595
45090306	45090329	19	+	27260156	PATU8988T	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.9495452600293433	[564]	[407,202,288,217]	-8	hSpCas9	negative selection	8697596
45251578	45251601	19	+	27260156	PATU8988T	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	-0.03650796543288182	[668]	[601,666,591,666]	0	hSpCas9	negative selection	8707018
45251613	45251636	19	-	27260156	PATU8988T	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.02464747866076822	[717]	[885,455,544,932]	0	hSpCas9	negative selection	8707019
45263324	45263347	19	+	27260156	PATU8988T	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-1.1337626356218133	[72]	[6,24,67,26]	-9	hSpCas9	negative selection	8707020
45090345	45090368	19	+	27260156	PATU8988T	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.16863424005527583	[411]	[518,545,437,282]	3	hSpCas9	negative selection	8761858
45090329	45090352	19	-	27260156	PATU8988T	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.4182563228561547	[400]	[370,279,246,258]	-6	hSpCas9	negative selection	8761859
45090370	45090393	19	+	27260156	PATU8988T	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.5061993519572324	[359]	[707,329,446,474]	8	hSpCas9	negative selection	8761860
45263354	45263377	19	-	27260156	PATU8988T	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.3722099862855752	[175]	[60,157,180,126]	-6	hSpCas9	negative selection	8771276
45263150	45263173	19	-	27260156	PATU8988T	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	-0.024027478287299675	[921]	[928,881,740,961]	0	hSpCas9	negative selection	8771277
45263145	45263168	19	+	27260156	PATU8988T	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.10247421991375029	[404]	[400,412,479,381]	1	hSpCas9	negative selection	8771278
45090297	45090320	19	-	27260156	T47D	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.7793229948950342	[319]	[239,218,173,236]	-9	hSpCas9	negative selection	8818845
45090197	45090220	19	+	27260156	T47D	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.026981916076973755	[610]	[812,580,703,818]	0	hSpCas9	negative selection	8818846
45090306	45090329	19	+	27260156	T47D	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.29519975614449295	[564]	[647,505,455,539]	-6	hSpCas9	negative selection	8818847
45251578	45251601	19	+	27260156	T47D	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.4886230465946739	[668]	[1171,1053,1040,1111]	8	hSpCas9	negative selection	8828269
45251613	45251636	19	-	27260156	T47D	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.024894940538734978	[717]	[929,796,726,838]	0	hSpCas9	negative selection	8828270
45263324	45263347	19	+	27260156	T47D	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.16321645648101102	[72]	[70,62,85,84]	-4	hSpCas9	negative selection	8828271
45090345	45090368	19	+	27260156	T47D	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.29503685920809036	[411]	[575,487,631,669]	6	hSpCas9	negative selection	8883109
45090329	45090352	19	-	27260156	T47D	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.3160273155601541	[400]	[419,402,277,399]	-6	hSpCas9	negative selection	8883110
45090370	45090393	19	+	27260156	T47D	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.10205354562304186	[359]	[459,419,425,498]	2	hSpCas9	negative selection	8883111
45263354	45263377	19	-	27260156	T47D	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.21108711788330825	[175]	[207,195,261,287]	4	hSpCas9	negative selection	8892527
45263150	45263173	19	-	27260156	T47D	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.11479189594973949	[921]	[1282,1061,1180,1133]	2	hSpCas9	negative selection	8892528
45263145	45263168	19	+	27260156	T47D	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.13454333458855555	[404]	[482,397,418,421]	-3	hSpCas9	negative selection	8892529
45090297	45090320	19	-	27260156	SU8686	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-1.9677812067306089	[319]	[83,74,42,128]	-9	hSpCas9	negative selection	8940096
45090197	45090220	19	+	27260156	SU8686	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.05235826720507042	[610]	[563,543,712,722]	0	hSpCas9	negative selection	8940097
45090306	45090329	19	+	27260156	SU8686	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.7564608865122204	[564]	[358,353,184,431]	-8	hSpCas9	negative selection	8940098
45251578	45251601	19	+	27260156	SU8686	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.6258435855977502	[668]	[813,985,1055,1305]	9	hSpCas9	negative selection	8949520
45251613	45251636	19	-	27260156	SU8686	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	0.08203226205808445	[717]	[621,552,696,1257]	1	hSpCas9	negative selection	8949521
45263324	45263347	19	+	27260156	SU8686	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-1.2936339191126143	[72]	[36,21,16,43]	-9	hSpCas9	negative selection	8949522
45090345	45090368	19	+	27260156	SU8686	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.4605816117023014	[411]	[655,477,472,648]	7	hSpCas9	negative selection	9004360
45090329	45090352	19	-	27260156	SU8686	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-1.2953553616276725	[400]	[163,176,183,111]	-9	hSpCas9	negative selection	9004361
45090370	45090393	19	+	27260156	SU8686	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.30763826909826714	[359]	[440,378,467,492]	5	hSpCas9	negative selection	9004362
45263354	45263377	19	-	27260156	SU8686	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.17516615507558853	[175]	[186,207,207,180]	3	hSpCas9	negative selection	9013778
45263150	45263173	19	-	27260156	SU8686	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	-0.23328864856342113	[921]	[632,815,863,810]	-4	hSpCas9	negative selection	9013779
45263145	45263168	19	+	27260156	SU8686	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.015031380589646287	[404]	[397,295,385,542]	0	hSpCas9	negative selection	9013780
45090297	45090320	19	-	27260156	SKES1	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	0.08690447725132522	[319]	[359,325,349,319]	2	hSpCas9	negative selection	9061347
45090197	45090220	19	+	27260156	SKES1	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.3325045155067701	[610]	[943,852,715,603]	7	hSpCas9	negative selection	9061348
45090306	45090329	19	+	27260156	SKES1	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	0.11078359905799157	[564]	[740,556,606,542]	2	hSpCas9	negative selection	9061349
45251578	45251601	19	+	27260156	SKES1	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.24845409819717246	[668]	[715,687,884,842]	5	hSpCas9	negative selection	9070771
45251613	45251636	19	-	27260156	SKES1	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.19065246558629806	[717]	[664,668,690,502]	-4	hSpCas9	negative selection	9070772
45263324	45263347	19	+	27260156	SKES1	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.021217487231129706	[72]	[175,71,44,14]	0	hSpCas9	negative selection	9070773
45090345	45090368	19	+	27260156	SKES1	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.5146168374112625	[411]	[833,559,520,472]	9	hSpCas9	negative selection	9125611
45090329	45090352	19	-	27260156	SKES1	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.43229713926243046	[400]	[289,276,324,287]	-7	hSpCas9	negative selection	9125612
45090370	45090393	19	+	27260156	SKES1	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.18312125197299758	[359]	[423,526,350,348]	4	hSpCas9	negative selection	9125613
45263354	45263377	19	-	27260156	SKES1	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.01615939244868625	[175]	[221,174,174,145]	0	hSpCas9	negative selection	9135029
45263150	45263173	19	-	27260156	SKES1	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	-0.010348069164939133	[921]	[969,906,873,900]	0	hSpCas9	negative selection	9135030
45263145	45263168	19	+	27260156	SKES1	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.3979562018125358	[404]	[287,327,266,336]	-7	hSpCas9	negative selection	9135031
45090297	45090320	19	-	27260156	TOV112D	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.6859283747976128	[319]	[191,215,189,201]	-8	hSpCas9	negative selection	9182598
45090197	45090220	19	+	27260156	TOV112D	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.1333986836440489	[610]	[791,824,703,417]	2	hSpCas9	negative selection	9182599
45090306	45090329	19	+	27260156	TOV112D	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.1720865235365058	[564]	[608,658,367,421]	-3	hSpCas9	negative selection	9182600
45251578	45251601	19	+	27260156	TOV112D	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.4161825296189997	[668]	[1275,1028,685,655]	7	hSpCas9	negative selection	9192022
45251613	45251636	19	-	27260156	TOV112D	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.03291190808830868	[717]	[520,959,914,468]	0	hSpCas9	negative selection	9192023
45263324	45263347	19	+	27260156	TOV112D	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.9851842722388091	[72]	[59,36,28,23]	-9	hSpCas9	negative selection	9192024
45090345	45090368	19	+	27260156	TOV112D	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.39918168332345294	[411]	[567,666,681,297]	7	hSpCas9	negative selection	9246862
45090329	45090352	19	-	27260156	TOV112D	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.5457975779274646	[400]	[256,325,288,239]	-8	hSpCas9	negative selection	9246863
45090370	45090393	19	+	27260156	TOV112D	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.010429961283951517	[359]	[407,269,248,501]	0	hSpCas9	negative selection	9246864
45263354	45263377	19	-	27260156	TOV112D	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.04234746891682484	[175]	[205,178,260,83]	0	hSpCas9	negative selection	9256280
45263150	45263173	19	-	27260156	TOV112D	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.04608531869302135	[921]	[1089,1165,852,771]	0	hSpCas9	negative selection	9256281
45263145	45263168	19	+	27260156	TOV112D	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.37153020760875716	[404]	[205,459,278,334]	-6	hSpCas9	negative selection	9256282
45090297	45090320	19	-	27260156	TC71	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.3754213825626943	[319]	[304,285,240,222]	-8	hSpCas9	negative selection	9303849
45090197	45090220	19	+	27260156	TC71	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	0.1816684480167134	[610]	[793,684,777,709]	4	hSpCas9	negative selection	9303850
45090306	45090329	19	+	27260156	TC71	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.10917459554977868	[564]	[498,602,539,608]	-3	hSpCas9	negative selection	9303851
45251578	45251601	19	+	27260156	TC71	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.22453449732030284	[668]	[605,1039,767,951]	5	hSpCas9	negative selection	9313273
45251613	45251636	19	-	27260156	TC71	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.0181439969573417	[717]	[676,721,739,912]	0	hSpCas9	negative selection	9313274
45263324	45263347	19	+	27260156	TC71	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.32990190539654707	[72]	[51,67,37,93]	-7	hSpCas9	negative selection	9313275
45090345	45090368	19	+	27260156	TC71	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.17073423258458864	[411]	[458,524,556,442]	4	hSpCas9	negative selection	9368113
45090329	45090352	19	-	27260156	TC71	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.22057496358443612	[400]	[376,397,278,427]	-5	hSpCas9	negative selection	9368114
45090370	45090393	19	+	27260156	TC71	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.1916059450891558	[359]	[337,487,518,415]	5	hSpCas9	negative selection	9368115
45263354	45263377	19	-	27260156	TC71	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	-0.16526736803519215	[175]	[167,201,135,167]	-4	hSpCas9	negative selection	9377531
45263150	45263173	19	-	27260156	TC71	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	-0.01879459335618816	[921]	[846,899,1069,1091]	0	hSpCas9	negative selection	9377532
45263145	45263168	19	+	27260156	TC71	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.044842400150662654	[404]	[357,444,384,502]	-1	hSpCas9	negative selection	9377533
45090297	45090320	19	-	27260156	TC32	viability	TGCGGAGGTAACGCTCCCGAAGG	MARK4	ENSG00000007047	-0.26844538137937035	[319]	[207,233,255,299]	-5	hSpCas9	negative selection	9425100
45090197	45090220	19	+	27260156	TC32	viability	ATGGACGCAGAGCCCCCTTGAGG	MARK4	ENSG00000007047	-0.0785853088034077	[610]	[566,281,822,621]	-1	hSpCas9	negative selection	9425101
45090306	45090329	19	+	27260156	TC32	viability	GCGTTACCTCCGCAGCCTGCTGG	MARK4	ENSG00000007047	-0.22107819586460042	[564]	[451,430,420,493]	-4	hSpCas9	negative selection	9425102
45251578	45251601	19	+	27260156	TC32	viability	ACCCGGAGAAGATGTCTTCGCGG	MARK4	ENSG00000007047	0.40602844027319795	[668]	[834,572,1126,900]	7	hSpCas9	negative selection	9434524
45251613	45251636	19	-	27260156	TC32	viability	TCCGAGTTCCGATCGTTGCCCGG	MARK4	ENSG00000007047	-0.051066786910675344	[717]	[583,392,876,872]	-1	hSpCas9	negative selection	9434525
45263324	45263347	19	+	27260156	TC32	viability	CCGAGAAGTCCGCATCATGAAGG	MARK4	ENSG00000007047	-0.08470014939903114	[72]	[44,51,60,105]	-1	hSpCas9	negative selection	9434526
45090345	45090368	19	+	27260156	TC32	viability	GGTGAGCTTCACGTTGCACGAGG	MARK4	ENSG00000007047	0.6208984438140499	[411]	[478,566,815,542]	9	hSpCas9	negative selection	9489364
45090329	45090352	19	-	27260156	TC32	viability	GCTCACCTGATGACCCACCATGG	MARK4	ENSG00000007047	-0.1836739094514881	[400]	[271,179,530,431]	-3	hSpCas9	negative selection	9489365
45090370	45090393	19	+	27260156	TC32	viability	GTGCGTGTGGCCGCCCACTTTGG	MARK4	ENSG00000007047	0.2708921486134639	[359]	[377,362,303,573]	5	hSpCas9	negative selection	9489366
45263354	45263377	19	-	27260156	TC32	viability	CCTCCTCACCGATGTTGGGGTGG	MARK4	ENSG00000007047	0.12713144353095873	[175]	[201,124,217,191]	2	hSpCas9	negative selection	9498782
45263150	45263173	19	-	27260156	TC32	viability	CCTCACCTTCTGCAGGCTGCTGG	MARK4	ENSG00000007047	0.2437422112589197	[921]	[848,759,1358,1270]	4	hSpCas9	negative selection	9498783
45263145	45263168	19	+	27260156	TC32	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.21455236569587205	[404]	[273,134,462,538]	-4	hSpCas9	negative selection	9498784
45251618	45251641	19	+	27869803	HPAFII	viability after 27 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.5131180777039932	[303]	[322,148,NaN]	4	hSpCas9	negative selection	9568469
45259004	45259027	19	+	27869803	HPAFII	viability after 27 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.08518483540049065	[214]	[36,188,NaN]	0	hSpCas9	negative selection	9568470
45263315	45263338	19	-	27869803	HPAFII	viability after 27 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.31379224252038396	[408]	[365,184,NaN]	2	hSpCas9	negative selection	9568471
45264724	45264747	19	-	27869803	HPAFII	viability after 27 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.17943270215250973	[102]	[79,20,NaN]	-1	hSpCas9	negative selection	9568472
45264865	45264888	19	+	27869803	HPAFII	viability after 27 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	-0.29601848598643776	[144]	[48,72,NaN]	-2	hSpCas9	negative selection	9568473
45271685	45271708	19	-	27869803	HPAFII	viability after 27 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.35380875329579986	[501]	[357,319,NaN]	3	hSpCas9	negative selection	9568474
45251618	45251641	19	+	27869803	HPAFII	viability after 15 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.46794441237963985	[303]	[581,370,NaN]	5	hSpCas9	negative selection	9650918
45259004	45259027	19	+	27869803	HPAFII	viability after 15 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.10551945407257146	[214]	[255,243,NaN]	1	hSpCas9	negative selection	9650919
45263315	45263338	19	-	27869803	HPAFII	viability after 15 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.3153352247434461	[408]	[726,434,NaN]	3	hSpCas9	negative selection	9650920
45264724	45264747	19	-	27869803	HPAFII	viability after 15 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	0.2349093497189958	[102]	[186,94,NaN]	2	hSpCas9	negative selection	9650921
45264865	45264888	19	+	27869803	HPAFII	viability after 15 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.4210467418942904	[144]	[191,218,NaN]	5	hSpCas9	negative selection	9650922
45271685	45271708	19	-	27869803	HPAFII	viability after 15 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.43908470727482096	[501]	[1011,556,NaN]	5	hSpCas9	negative selection	9650923
45251618	45251641	19	+	27869803	ASPC1	viability after 36 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.05298388695144751	[942]	[136,511,345]	0	hSpCas9	negative selection	9733367
45259004	45259027	19	+	27869803	ASPC1	viability after 36 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.5764193678880009	[587]	[424,230,278]	6	hSpCas9	negative selection	9733368
45263315	45263338	19	-	27869803	ASPC1	viability after 36 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.16209417161446182	[1004]	[531,653,82]	1	hSpCas9	negative selection	9733369
45264724	45264747	19	-	27869803	ASPC1	viability after 36 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	0.22673708371331147	[338]	[22,38,296]	2	hSpCas9	negative selection	9733370
45264865	45264888	19	+	27869803	ASPC1	viability after 36 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.2045855659277892	[341]	[166,49,184]	2	hSpCas9	negative selection	9733371
45271685	45271708	19	-	27869803	ASPC1	viability after 36 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	-0.06369666903186455	[1106]	[374,476,276]	0	hSpCas9	negative selection	9733372
45251618	45251641	19	+	27869803	PATU8988S	viability after 35 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.13759862143069496	[787]	[286,289,NaN]	-1	hSpCas9	negative selection	9815816
45259004	45259027	19	+	27869803	PATU8988S	viability after 35 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.32763477314015793	[530]	[217,318,NaN]	4	hSpCas9	negative selection	9815817
45263315	45263338	19	-	27869803	PATU8988S	viability after 35 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.8777285418322887	[782]	[559,598,NaN]	8	hSpCas9	negative selection	9815818
45264724	45264747	19	-	27869803	PATU8988S	viability after 35 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	1.2067257205395012	[168]	[201,111,NaN]	9	hSpCas9	negative selection	9815819
45264865	45264888	19	+	27869803	PATU8988S	viability after 35 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.12798309550056264	[315]	[171,105,NaN]	1	hSpCas9	negative selection	9815820
45271685	45271708	19	-	27869803	PATU8988S	viability after 35 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.10361422988004176	[916]	[318,474,NaN]	1	hSpCas9	negative selection	9815821
45251618	45251641	19	+	27869803	PATU8988S	viability after 31 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	-0.16183370501771144	[787]	[224,351,NaN]	-2	hSpCas9	negative selection	9898265
45259004	45259027	19	+	27869803	PATU8988S	viability after 31 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.1649319442960337	[530]	[122,382,NaN]	2	hSpCas9	negative selection	9898266
45263315	45263338	19	-	27869803	PATU8988S	viability after 31 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.7193187095713958	[782]	[484,550,NaN]	8	hSpCas9	negative selection	9898267
45264724	45264747	19	-	27869803	PATU8988S	viability after 31 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	1.173429176113042	[168]	[107,207,NaN]	9	hSpCas9	negative selection	9898268
45264865	45264888	19	+	27869803	PATU8988S	viability after 31 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.08701678555075354	[315]	[117,153,NaN]	1	hSpCas9	negative selection	9898269
45271685	45271708	19	-	27869803	PATU8988S	viability after 31 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.038981150604648906	[916]	[288,485,NaN]	0	hSpCas9	negative selection	9898270
45251618	45251641	19	+	27869803	HPAFII	viability after 35 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	1.0975946281843705	[303]	[421,224,NaN]	7	hSpCas9	negative selection	9980714
45259004	45259027	19	+	27869803	HPAFII	viability after 35 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.023010470765020358	[214]	[0,233,NaN]	0	hSpCas9	negative selection	9980715
45263315	45263338	19	-	27869803	HPAFII	viability after 35 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	-0.2123801191917043	[408]	[189,165,NaN]	-1	hSpCas9	negative selection	9980716
45264724	45264747	19	-	27869803	HPAFII	viability after 35 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	-0.37565723387589456	[102]	[66,9,NaN]	-2	hSpCas9	negative selection	9980717
45264865	45264888	19	+	27869803	HPAFII	viability after 35 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	0.28194375394779364	[144]	[116,57,NaN]	1	hSpCas9	negative selection	9980718
45271685	45271708	19	-	27869803	HPAFII	viability after 35 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.9549590373006245	[501]	[494,489,NaN]	6	hSpCas9	negative selection	9980719
45251618	45251641	19	+	27869803	HPAFII	viability after 31 days	CAACGATCGGAACTCGGACACGG	MARK4	ENSG00000007047	0.7585854003575274	[303]	[302,272,NaN]	5	hSpCas9	negative selection	10063163
45259004	45259027	19	+	27869803	HPAFII	viability after 31 days	AGTGGCCGCTCCTCGGACAAAGG	MARK4	ENSG00000007047	0.10302074227622794	[214]	[19,248,NaN]	0	hSpCas9	negative selection	10063164
45263315	45263338	19	-	27869803	HPAFII	viability after 31 days	TGCGGACTTCTCGGAACAGCTGG	MARK4	ENSG00000007047	0.11704358211297139	[408]	[347,140,NaN]	0	hSpCas9	negative selection	10063165
45264724	45264747	19	-	27869803	HPAFII	viability after 31 days	CACTTGCGTACTCCATCACCAGG	MARK4	ENSG00000007047	0.09089243380075285	[102]	[62,59,NaN]	0	hSpCas9	negative selection	10063166
45264865	45264888	19	+	27869803	HPAFII	viability after 31 days	GCATGGCCGCATGAAGGAGAAGG	MARK4	ENSG00000007047	-0.22241657851048935	[144]	[52,87,NaN]	-1	hSpCas9	negative selection	10063167
45271685	45271708	19	-	27869803	HPAFII	viability after 31 days	TTGAGGTTGTGCCCGTCGAAGGG	MARK4	ENSG00000007047	0.848401110694597	[501]	[445,573,NaN]	6	hSpCas9	negative selection	10063168
45264712	45264735	19	+	28162770	P31FUJ	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.37410284918745484	[347]	[529]	4	hSpCas9	negative selection	10189446
45263145	45263168	19	+	28162770	P31FUJ	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.31241937247774665	[148]	[140]	-3	hSpCas9	negative selection	10189447
45271587	45271610	19	-	28162770	P31FUJ	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	0.4590755002232896	[77]	[125]	5	hSpCas9	negative selection	10189448
45271681	45271704	19	-	28162770	P31FUJ	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	0.5383325297304722	[241]	[412]	6	hSpCas9	negative selection	10189449
45278566	45278589	19	+	28162770	P31FUJ	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	0.4503406902456808	[70]	[113]	5	hSpCas9	negative selection	10189450
45287621	45287644	19	+	28162770	P31FUJ	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-1.512910123607114	[16]	[6]	-7	hSpCas9	negative selection	10189451
45297933	45297956	19	+	28162770	P31FUJ	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	0.3281548332959884	[100]	[148]	3	hSpCas9	negative selection	10189452
45251611	45251634	19	-	28162770	P31FUJ	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-0.5162561514871052	[369]	[303]	-4	hSpCas9	negative selection	10189453
45259117	45259140	19	+	28162770	P31FUJ	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	-0.36721123784469023	[325]	[296]	-3	hSpCas9	negative selection	10189454
45259168	45259191	19	+	28162770	P31FUJ	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	0.5508798886588578	[236]	[407]	6	hSpCas9	negative selection	10189455
45264712	45264735	19	+	28162770	TF1	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	NaN	[NaN]	[292]	1	hSpCas9	negative selection	10358812
45263145	45263168	19	+	28162770	TF1	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	NaN	[NaN]	[139]	1	hSpCas9	negative selection	10358813
45271587	45271610	19	-	28162770	TF1	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10358814
45271681	45271704	19	-	28162770	TF1	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10358815
45278566	45278589	19	+	28162770	TF1	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10358816
45287621	45287644	19	+	28162770	TF1	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10358817
45297933	45297956	19	+	28162770	TF1	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10358818
45251611	45251634	19	-	28162770	TF1	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10358819
45259117	45259140	19	+	28162770	TF1	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10358820
45259168	45259191	19	+	28162770	TF1	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	NaN	[NaN]	[102]	1	hSpCas9	negative selection	10358821
45264712	45264735	19	+	28162770	SKM1	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.5547188697057361	[123]	[321]	5	hSpCas9	negative selection	10528178
45263145	45263168	19	+	28162770	SKM1	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.38950240717170603	[37]	[87]	4	hSpCas9	negative selection	10528179
45271587	45271610	19	-	28162770	SKM1	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-1.2179303743531449	[24]	[18]	-7	hSpCas9	negative selection	10528180
45271681	45271704	19	-	28162770	SKM1	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	0.21864028647534045	[69]	[143]	2	hSpCas9	negative selection	10528181
45278566	45278589	19	+	28162770	SKM1	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	0.3943162089047582	[33]	[78]	4	hSpCas9	negative selection	10528182
45287621	45287644	19	+	28162770	SKM1	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-0.2370391973008492	[5]	[8]	-2	hSpCas9	negative selection	10528183
45297933	45297956	19	+	28162770	SKM1	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	0.42311079981452604	[26]	[63]	4	hSpCas9	negative selection	10528184
45251611	45251634	19	-	28162770	SKM1	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	0.03504034813595158	[105]	[191]	0	hSpCas9	negative selection	10528185
45259117	45259140	19	+	28162770	SKM1	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	-0.3133900834309641	[96]	[137]	-3	hSpCas9	negative selection	10528186
45259168	45259191	19	+	28162770	SKM1	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	1.0870246419305039	[44]	[168]	8	hSpCas9	negative selection	10528187
45264712	45264735	19	+	28162770	SKM1	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.5547188697057361	[123]	[321]	5	hSpCas9	negative selection	10697544
45263145	45263168	19	+	28162770	SKM1	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.38950240717170603	[37]	[87]	4	hSpCas9	negative selection	10697545
45271587	45271610	19	-	28162770	SKM1	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-1.2179303743531449	[24]	[18]	-7	hSpCas9	negative selection	10697546
45271681	45271704	19	-	28162770	SKM1	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	0.21864028647534045	[69]	[143]	2	hSpCas9	negative selection	10697547
45278566	45278589	19	+	28162770	SKM1	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	0.3943162089047582	[33]	[78]	4	hSpCas9	negative selection	10697548
45287621	45287644	19	+	28162770	SKM1	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-0.2370391973008492	[5]	[8]	-2	hSpCas9	negative selection	10697549
45297933	45297956	19	+	28162770	SKM1	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	0.42311079981452604	[26]	[63]	4	hSpCas9	negative selection	10697550
45251611	45251634	19	-	28162770	SKM1	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	0.03504034813595158	[105]	[191]	0	hSpCas9	negative selection	10697551
45259117	45259140	19	+	28162770	SKM1	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	-0.3133900834309641	[96]	[137]	-3	hSpCas9	negative selection	10697552
45259168	45259191	19	+	28162770	SKM1	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	1.0870246419305039	[44]	[168]	8	hSpCas9	negative selection	10697553
45264712	45264735	19	+	28162770	PL21	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	-0.6500615629923598	[392]	[108]	-4	hSpCas9	negative selection	10866910
45263145	45263168	19	+	28162770	PL21	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.4763494090708472	[108]	[65]	4	hSpCas9	negative selection	10866911
45271587	45271610	19	-	28162770	PL21	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-1.5934095080432533	[103]	[14]	-7	hSpCas9	negative selection	10866912
45271681	45271704	19	-	28162770	PL21	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	1.0710320118604415	[256]	[234]	8	hSpCas9	negative selection	10866913
45278566	45278589	19	+	28162770	PL21	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	-0.44096596426936985	[130]	[41]	-3	hSpCas9	negative selection	10866914
45287621	45287644	19	+	28162770	PL21	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	2.2445337338477733	[15]	[32]	9	hSpCas9	negative selection	10866915
45297933	45297956	19	+	28162770	PL21	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	0.496532617269545	[56]	[34]	4	hSpCas9	negative selection	10866916
45251611	45251634	19	-	28162770	PL21	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	0.2775441181749268	[253]	[133]	2	hSpCas9	negative selection	10866917
45259117	45259140	19	+	28162770	PL21	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	0.08108694284555694	[201]	[92]	0	hSpCas9	negative selection	10866918
45259168	45259191	19	+	28162770	PL21	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	1.4364376378509864	[117]	[138]	9	hSpCas9	negative selection	10866919
45264712	45264735	19	+	28162770	P31FUJ	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.37410284918745484	[347]	[529]	4	hSpCas9	negative selection	11036276
45263145	45263168	19	+	28162770	P31FUJ	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.31241937247774665	[148]	[140]	-3	hSpCas9	negative selection	11036277
45271587	45271610	19	-	28162770	P31FUJ	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	0.4590755002232896	[77]	[125]	5	hSpCas9	negative selection	11036278
45271681	45271704	19	-	28162770	P31FUJ	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	0.5383325297304722	[241]	[412]	6	hSpCas9	negative selection	11036279
45278566	45278589	19	+	28162770	P31FUJ	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	0.4503406902456808	[70]	[113]	5	hSpCas9	negative selection	11036280
45287621	45287644	19	+	28162770	P31FUJ	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-1.512910123607114	[16]	[6]	-7	hSpCas9	negative selection	11036281
45297933	45297956	19	+	28162770	P31FUJ	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	0.3281548332959884	[100]	[148]	3	hSpCas9	negative selection	11036282
45251611	45251634	19	-	28162770	P31FUJ	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-0.5162561514871052	[369]	[303]	-4	hSpCas9	negative selection	11036283
45259117	45259140	19	+	28162770	P31FUJ	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	-0.36721123784469023	[325]	[296]	-3	hSpCas9	negative selection	11036284
45259168	45259191	19	+	28162770	P31FUJ	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	0.5508798886588578	[236]	[407]	6	hSpCas9	negative selection	11036285
45264712	45264735	19	+	28162770	OCIAML5	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	-0.20821038108927215	[303]	[474]	-1	hSpCas9	negative selection	11205642
45263145	45263168	19	+	28162770	OCIAML5	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.3673785664221143	[69]	[162]	3	hSpCas9	negative selection	11205643
45271587	45271610	19	-	28162770	OCIAML5	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-0.8296987578355425	[63]	[64]	-5	hSpCas9	negative selection	11205644
45271681	45271704	19	-	28162770	OCIAML5	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	-0.33252714514088944	[202]	[290]	-2	hSpCas9	negative selection	11205645
45278566	45278589	19	+	28162770	OCIAML5	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	0.7877578648916775	[42]	[133]	7	hSpCas9	negative selection	11205646
45287621	45287644	19	+	28162770	OCIAML5	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	1.9552883511936074	[4]	[34]	9	hSpCas9	negative selection	11205647
45297933	45297956	19	+	28162770	OCIAML5	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	-0.5252562545968884	[58]	[73]	-4	hSpCas9	negative selection	11205648
45251611	45251634	19	-	28162770	OCIAML5	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	0.26835646916074085	[223]	[486]	2	hSpCas9	negative selection	11205649
45259117	45259140	19	+	28162770	OCIAML5	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	0.9819234776970738	[137]	[491]	8	hSpCas9	negative selection	11205650
45259168	45259191	19	+	28162770	OCIAML5	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	0.2626120331721976	[138]	[300]	2	hSpCas9	negative selection	11205651
45264712	45264735	19	+	28162770	EOL1	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.5347943118948908	[772]	[589]	5	hSpCas9	negative selection	11375008
45263145	45263168	19	+	28162770	EOL1	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.6511369155626108	[154]	[51]	-5	hSpCas9	negative selection	11375009
45271587	45271610	19	-	28162770	EOL1	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	0.3030593948242646	[119]	[77]	2	hSpCas9	negative selection	11375010
45271681	45271704	19	-	28162770	EOL1	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	0.591873295219176	[538]	[427]	5	hSpCas9	negative selection	11375011
45278566	45278589	19	+	28162770	EOL1	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	-0.2730521883146262	[249]	[108]	-2	hSpCas9	negative selection	11375012
45287621	45287644	19	+	28162770	EOL1	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-0.627993251458244	[43]	[14]	-4	hSpCas9	negative selection	11375013
45297933	45297956	19	+	28162770	EOL1	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	-0.8556710205495555	[78]	[22]	-5	hSpCas9	negative selection	11375014
45251611	45251634	19	-	28162770	EOL1	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-0.40874657826677274	[445]	[176]	-3	hSpCas9	negative selection	11375015
45259117	45259140	19	+	28162770	EOL1	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	1.260831159434967	[239]	[302]	9	hSpCas9	negative selection	11375016
45259168	45259191	19	+	28162770	EOL1	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	1.7076374152505025	[196]	[338]	9	hSpCas9	negative selection	11375017
45264712	45264735	19	+	28162770	MOLM13	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.287491048872758	[552]	[487]	2	hSpCas9	negative selection	11544374
45263145	45263168	19	+	28162770	MOLM13	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.2491172758868279	[198]	[170]	1	hSpCas9	negative selection	11544375
45271587	45271610	19	-	28162770	MOLM13	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-0.7583864742790971	[123]	[52]	-4	hSpCas9	negative selection	11544376
45271681	45271704	19	-	28162770	MOLM13	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	1.2018618313988014	[385]	[641]	8	hSpCas9	negative selection	11544377
45278566	45278589	19	+	28162770	MOLM13	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	-0.8961641890154601	[138]	[53]	-5	hSpCas9	negative selection	11544378
45287621	45287644	19	+	28162770	MOLM13	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-4.232550336596514	[25]	[0]	-9	hSpCas9	negative selection	11544379
45297933	45297956	19	+	28162770	MOLM13	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	-1.4796431985612857	[80]	[20]	-6	hSpCas9	negative selection	11544380
45251611	45251634	19	-	28162770	MOLM13	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	0.31546327239765953	[378]	[340]	2	hSpCas9	negative selection	11544381
45259117	45259140	19	+	28162770	MOLM13	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	0.26558120625146336	[320]	[278]	2	hSpCas9	negative selection	11544382
45259168	45259191	19	+	28162770	MOLM13	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	0.9303398232982045	[216]	[298]	7	hSpCas9	negative selection	11544383
45264712	45264735	19	+	28162770	HEL	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.8512655300286299	[462]	[534]	7	hSpCas9	negative selection	11713740
45263145	45263168	19	+	28162770	HEL	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	1.7847578368727848	[115]	[255]	9	hSpCas9	negative selection	11713741
45271587	45271610	19	-	28162770	HEL	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-1.2279781510546766	[127]	[34]	-6	hSpCas9	negative selection	11713742
45271681	45271704	19	-	28162770	HEL	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	1.1141247206929021	[294]	[408]	8	hSpCas9	negative selection	11713743
45278566	45278589	19	+	28162770	HEL	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	0.4153283358972845	[143]	[122]	3	hSpCas9	negative selection	11713744
45287621	45287644	19	+	28162770	HEL	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	0.527261614580421	[25]	[23]	4	hSpCas9	negative selection	11713745
45297933	45297956	19	+	28162770	HEL	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	0.09730469546583809	[107]	[73]	0	hSpCas9	negative selection	11713746
45251611	45251634	19	-	28162770	HEL	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-0.2497080268448398	[322]	[173]	-2	hSpCas9	negative selection	11713747
45259117	45259140	19	+	28162770	HEL	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	0.05515086187237733	[274]	[182]	0	hSpCas9	negative selection	11713748
45259168	45259191	19	+	28162770	HEL	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	-0.8011797872656159	[184]	[67]	-5	hSpCas9	negative selection	11713749
45264712	45264735	19	+	28162770	MV411	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	-0.22011178565721068	[400]	[289]	-2	hSpCas9	negative selection	11883106
45263145	45263168	19	+	28162770	MV411	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	-0.9224874506595371	[107]	[47]	-6	hSpCas9	negative selection	11883107
45271587	45271610	19	-	28162770	MV411	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-1.0255809436236403	[86]	[35]	-6	hSpCas9	negative selection	11883108
45271681	45271704	19	-	28162770	MV411	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	0.43452310338327055	[259]	[295]	4	hSpCas9	negative selection	11883109
45278566	45278589	19	+	28162770	MV411	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	-0.5230806030944575	[115]	[67]	-4	hSpCas9	negative selection	11883110
45287621	45287644	19	+	28162770	MV411	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-2.3964186389919493	[24]	[3]	-8	hSpCas9	negative selection	11883111
45297933	45297956	19	+	28162770	MV411	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	0.49136313366886464	[75]	[89]	4	hSpCas9	negative selection	11883112
45251611	45251634	19	-	28162770	MV411	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-1.442394067792336	[270]	[83]	-7	hSpCas9	negative selection	11883113
45259117	45259140	19	+	28162770	MV411	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	0.8296494404878969	[174]	[261]	7	hSpCas9	negative selection	11883114
45259168	45259191	19	+	28162770	MV411	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	-0.6594530448257432	[134]	[71]	-5	hSpCas9	negative selection	11883115
45264712	45264735	19	+	28162770	MONOMAC1	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.652021254865707	[301]	[543]	6	hSpCas9	negative selection	12052472
45263145	45263168	19	+	28162770	MONOMAC1	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.5146176585774649	[68]	[112]	5	hSpCas9	negative selection	12052473
45271587	45271610	19	-	28162770	MONOMAC1	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-0.28276672108543766	[51]	[48]	-3	hSpCas9	negative selection	12052474
45271681	45271704	19	-	28162770	MONOMAC1	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	-0.5255077878136879	[220]	[175]	-4	hSpCas9	negative selection	12052475
45278566	45278589	19	+	28162770	MONOMAC1	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	0.8889363760502991	[56]	[120]	7	hSpCas9	negative selection	12052476
45287621	45287644	19	+	28162770	MONOMAC1	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-0.027111845617241226	[15]	[17]	0	hSpCas9	negative selection	12052477
45297933	45297956	19	+	28162770	MONOMAC1	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	-1.5545888516776374	[40]	[15]	-8	hSpCas9	negative selection	12052478
45251611	45251634	19	-	28162770	MONOMAC1	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-0.5596069264442621	[161]	[125]	-5	hSpCas9	negative selection	12052479
45259117	45259140	19	+	28162770	MONOMAC1	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	-0.4370879348925083	[136]	[115]	-4	hSpCas9	negative selection	12052480
45259168	45259191	19	+	28162770	MONOMAC1	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	0.0439712524442412	[131]	[155]	0	hSpCas9	negative selection	12052481
45264712	45264735	19	+	28162770	OCIAML2	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	-0.027347946598193618	[97]	[532]	0	hSpCas9	negative selection	12221838
45263145	45263168	19	+	28162770	OCIAML2	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	1.6420703075072012	[9]	[172]	9	hSpCas9	negative selection	12221839
45271587	45271610	19	-	28162770	OCIAML2	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	-0.5500642927365664	[13]	[52]	-4	hSpCas9	negative selection	12221840
45271681	45271704	19	-	28162770	OCIAML2	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	0.7334617793513429	[50]	[469]	7	hSpCas9	negative selection	12221841
45278566	45278589	19	+	28162770	OCIAML2	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	1.272334509545488	[17]	[240]	9	hSpCas9	negative selection	12221842
45287621	45287644	19	+	28162770	OCIAML2	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-2.4706298252421615	[1]	[1]	-8	hSpCas9	negative selection	12221843
45297933	45297956	19	+	28162770	OCIAML2	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	0.766409372058688	[6]	[65]	7	hSpCas9	negative selection	12221844
45251611	45251634	19	-	28162770	OCIAML2	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-0.2560357744661205	[52]	[245]	-2	hSpCas9	negative selection	12221845
45259117	45259140	19	+	28162770	OCIAML2	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	0.5013557985882422	[38]	[305]	5	hSpCas9	negative selection	12221846
45259168	45259191	19	+	28162770	OCIAML2	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	-0.622632918687211	[29]	[107]	-5	hSpCas9	negative selection	12221847
45264712	45264735	19	+	28162770	OCIAML3	viability	GAAGACGCTGTACCTGGTGATGG	MARK4	ENSG00000007047	0.5572359400520742	[94]	[421]	5	hSpCas9	negative selection	12391204
45263145	45263168	19	+	28162770	OCIAML3	viability	GAATCCCAGCAGCCTGCAGAAGG	MARK4	ENSG00000007047	0.7942629493918953	[16]	[88]	7	hSpCas9	negative selection	12391205
45271587	45271610	19	-	28162770	OCIAML3	viability	GCCCTGAAACAGCTCCGGGGCGG	MARK4	ENSG00000007047	0.21334728173344086	[25]	[90]	2	hSpCas9	negative selection	12391206
45271681	45271704	19	-	28162770	OCIAML3	viability	GGTTGTGCCCGTCGAAGGGCAGG	MARK4	ENSG00000007047	0.23998240823690775	[68]	[245]	2	hSpCas9	negative selection	12391207
45278566	45278589	19	+	28162770	OCIAML3	viability	GAAGCCATACACAGAGCCCGAGG	MARK4	ENSG00000007047	-0.23645563570607953	[31]	[81]	-2	hSpCas9	negative selection	12391208
45287621	45287644	19	+	28162770	OCIAML3	viability	AGGCAGAGATCCCAGAGCGGCGG	MARK4	ENSG00000007047	-1.33097323449037	[4]	[5]	-7	hSpCas9	negative selection	12391209
45297933	45297956	19	+	28162770	OCIAML3	viability	TGACCTCCAAACTGACCCGAAGG	MARK4	ENSG00000007047	1.375618710632318	[17]	[140]	9	hSpCas9	negative selection	12391210
45251611	45251634	19	-	28162770	OCIAML3	viability	CGAGTTCCGATCGTTGCCCGGGG	MARK4	ENSG00000007047	-0.5084319086180891	[89]	[190]	-4	hSpCas9	negative selection	12391211
45259117	45259140	19	+	28162770	OCIAML3	viability	CCTGCTGAGGACCATTGGGAAGG	MARK4	ENSG00000007047	0.17152710603881371	[79]	[271]	1	hSpCas9	negative selection	12391212
45259168	45259191	19	+	28162770	OCIAML3	viability	GCACATCCTCACTGGTCGGGAGG	MARK4	ENSG00000007047	0.20206147418692605	[54]	[190]	2	hSpCas9	negative selection	12391213