Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4147
• Symbol:MATN2
• Description:matrilin 2

DataSource: http://genomecrispr.dkfz.de/#!/results/MATN2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
98007142	98007165	8	+	26472758	Jiyoye	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	-0.06150008137504387	[136]	[98]	0	hSpCas9	negative selection	96930
97888192	97888215	8	-	26472758	Jiyoye	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.05977420641544029	[480]	[347]	0	hSpCas9	negative selection	96931
97931294	97931317	8	-	26472758	Jiyoye	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.7090657231566909	[231]	[285]	5	hSpCas9	negative selection	96932
98003740	98003763	8	-	26472758	Jiyoye	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	1.3768017324623547	[23]	[46]	8	hSpCas9	negative selection	96933
98007565	98007588	8	+	26472758	Jiyoye	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	1.2680535793575558	[222]	[404]	7	hSpCas9	negative selection	96934
98018076	98018099	8	+	26472758	Jiyoye	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	0.35095937193932536	[156]	[150]	2	hSpCas9	negative selection	96935
98007142	98007165	8	+	26472758	KBM7	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.05986875538033329	[414,357]	[180,195]	0	hSpCas9	negative selection	288048
97888192	97888215	8	-	26472758	KBM7	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.24637759364877532	[1862,1450]	[516,771]	-2	hSpCas9	negative selection	288049
97931294	97931317	8	-	26472758	KBM7	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.37010920036212447	[1304,859]	[718,582]	4	hSpCas9	negative selection	288050
98003740	98003763	8	-	26472758	KBM7	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	-1.2967902307029446	[195,61]	[32,14]	-7	hSpCas9	negative selection	288051
98007565	98007588	8	+	26472758	KBM7	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	-0.2361101492913078	[1441,1565]	[551,653]	-2	hSpCas9	negative selection	288052
98018076	98018099	8	+	26472758	KBM7	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	-0.5638454595298128	[683,355]	[134,183]	-5	hSpCas9	negative selection	288053
98007142	98007165	8	+	26472758	Raji	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.6751562747972406	[196]	[72]	6	hSpCas9	negative selection	479166
97888192	97888215	8	-	26472758	Raji	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	0.2942346495410213	[997]	[283]	2	hSpCas9	negative selection	479167
97931294	97931317	8	-	26472758	Raji	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.40173955222998026	[485]	[148]	4	hSpCas9	negative selection	479168
98003740	98003763	8	-	26472758	Raji	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	0.02765634290286556	[92]	[21]	0	hSpCas9	negative selection	479169
98007565	98007588	8	+	26472758	Raji	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	0.5309325345079607	[506]	[169]	5	hSpCas9	negative selection	479170
98018076	98018099	8	+	26472758	Raji	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	-0.6439373517696765	[302]	[44]	-5	hSpCas9	negative selection	479171
98007142	98007165	8	+	26472758	K562	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.2603017692731019	[270]	[273]	2	hSpCas9	negative selection	670284
97888192	97888215	8	-	26472758	K562	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	0.03757565363798365	[1414]	[1225]	0	hSpCas9	negative selection	670285
97931294	97931317	8	-	26472758	K562	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.06884716308299244	[671]	[594]	0	hSpCas9	negative selection	670286
98003740	98003763	8	-	26472758	K562	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	1.468586773892746	[115]	[270]	9	hSpCas9	negative selection	670287
98007565	98007588	8	+	26472758	K562	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	0.2610653935984537	[1033]	[1045]	2	hSpCas9	negative selection	670288
98018076	98018099	8	+	26472758	K562	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	0.49387016122731564	[248]	[295]	4	hSpCas9	negative selection	670289
97888145	97888168	8	+	26627737	DLD1	viability	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	-1.6901092184309658	[145]	[38,3,0]	-8	hSpCas9	negative selection	840444
97930963	97930986	8	+	26627737	DLD1	viability	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	0.9295060861488211	[706]	[384,484,398]	8	hSpCas9	negative selection	840445
97941814	97941837	8	-	26627737	DLD1	viability	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	0.46636988177108174	[975]	[539,465,281]	5	hSpCas9	negative selection	840446
97961481	97961504	8	-	26627737	DLD1	viability	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.24614301485582885	[422]	[101,121,110]	-3	hSpCas9	negative selection	840447
98003687	98003710	8	-	26627737	DLD1	viability	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.4006472778137683	[860]	[237,382,433]	4	hSpCas9	negative selection	840448
98007187	98007210	8	+	26627737	DLD1	viability	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.5195175705622896	[719]	[369,274,320]	5	hSpCas9	negative selection	840449
97888145	97888168	8	+	26627737	GBM cells	viability after 5 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	0.3463728518569069	[32]	[19,24]	5	hSpCas9	negative selection	922759
97930963	97930986	8	+	26627737	GBM cells	viability after 5 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	-0.04450259674794699	[424]	[245,195]	0	hSpCas9	negative selection	922760
97941814	97941837	8	-	26627737	GBM cells	viability after 5 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.5748697156113237	[542]	[196,193]	-7	hSpCas9	negative selection	922761
97961481	97961504	8	-	26627737	GBM cells	viability after 5 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.13228074671790852	[186]	[98,83]	-2	hSpCas9	negative selection	922762
98003687	98003710	8	-	26627737	GBM cells	viability after 5 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.2539363710627166	[361]	[223,238]	4	hSpCas9	negative selection	922763
98007187	98007210	8	+	26627737	GBM cells	viability after 5 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.06344964689757626	[595]	[334,332]	1	hSpCas9	negative selection	922764
97888145	97888168	8	+	26627737	GBM cells	viability after 13 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	0.47774123199508534	[32]	[30,19]	6	hSpCas9	negative selection	1005074
97930963	97930986	8	+	26627737	GBM cells	viability after 13 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	0.3090596302068106	[424]	[347,234]	4	hSpCas9	negative selection	1005075
97941814	97941837	8	-	26627737	GBM cells	viability after 13 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.573830908914589	[542]	[203,192]	-6	hSpCas9	negative selection	1005076
97961481	97961504	8	-	26627737	GBM cells	viability after 13 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	0.007738002421471213	[186]	[117,88]	0	hSpCas9	negative selection	1005077
98003687	98003710	8	-	26627737	GBM cells	viability after 13 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.37256979985873584	[361]	[277,234]	5	hSpCas9	negative selection	1005078
98007187	98007210	8	+	26627737	GBM cells	viability after 13 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.15399187610636034	[595]	[377,344]	2	hSpCas9	negative selection	1005079
97888145	97888168	8	+	26627737	GBM cells	viability after 21 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	1.389063135862471	[32]	[47,45]	9	hSpCas9	negative selection	1087389
97930963	97930986	8	+	26627737	GBM cells	viability after 21 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	-0.03901541503371386	[424]	[230,218]	0	hSpCas9	negative selection	1087390
97941814	97941837	8	-	26627737	GBM cells	viability after 21 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.70685628595951	[542]	[186,174]	-6	hSpCas9	negative selection	1087391
97961481	97961504	8	-	26627737	GBM cells	viability after 21 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	0.03069257799537145	[186]	[108,98]	0	hSpCas9	negative selection	1087392
98003687	98003710	8	-	26627737	GBM cells	viability after 21 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.599932426194366	[361]	[307,288]	6	hSpCas9	negative selection	1087393
98007187	98007210	8	+	26627737	GBM cells	viability after 21 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.21629298162417654	[595]	[383,368]	2	hSpCas9	negative selection	1087394
97888145	97888168	8	+	26627737	RPE1	viability after 9 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	-2.550180554036332	[565]	[31,27]	-9	hSpCas9	negative selection	1169704
97930963	97930986	8	+	26627737	RPE1	viability after 9 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	-0.5373227793527334	[1818]	[277,539]	-4	hSpCas9	negative selection	1169705
97941814	97941837	8	-	26627737	RPE1	viability after 9 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	0.02490071508460745	[1879]	[693,475]	0	hSpCas9	negative selection	1169706
97961481	97961504	8	-	26627737	RPE1	viability after 9 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	1.620187439809106	[237]	[132,352]	8	hSpCas9	negative selection	1169707
98003687	98003710	8	-	26627737	RPE1	viability after 9 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	1.4647775412172424	[867]	[784,704]	7	hSpCas9	negative selection	1169708
98007187	98007210	8	+	26627737	RPE1	viability after 9 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.4045370948095024	[1614]	[546,826]	3	hSpCas9	negative selection	1169709
97888145	97888168	8	+	26627737	RPE1	viability after 12 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	-1.9143054748325303	[565]	[0,81]	-8	hSpCas9	negative selection	1252019
97930963	97930986	8	+	26627737	RPE1	viability after 12 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	-0.7172507489803238	[1818]	[237,359]	-5	hSpCas9	negative selection	1252020
97941814	97941837	8	-	26627737	RPE1	viability after 12 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	0.39884904351049344	[1879]	[918,397]	2	hSpCas9	negative selection	1252021
97961481	97961504	8	-	26627737	RPE1	viability after 12 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	1.9730014155129894	[237]	[183,321]	8	hSpCas9	negative selection	1252022
98003687	98003710	8	-	26627737	RPE1	viability after 12 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	1.6248093898557436	[867]	[606,837]	8	hSpCas9	negative selection	1252023
98007187	98007210	8	+	26627737	RPE1	viability after 12 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.8412002102169036	[1614]	[686,872]	5	hSpCas9	negative selection	1252024
97888145	97888168	8	+	26627737	RPE1	viability after 15 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	-2.2340072388660315	[565]	[3,62]	-8	hSpCas9	negative selection	1334334
97930963	97930986	8	+	26627737	RPE1	viability after 15 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	-0.9020308914314477	[1818]	[170,375]	-5	hSpCas9	negative selection	1334335
97941814	97941837	8	-	26627737	RPE1	viability after 15 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	0.03003430401967333	[1879]	[739,352]	0	hSpCas9	negative selection	1334336
97961481	97961504	8	-	26627737	RPE1	viability after 15 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	2.032152294186001	[237]	[338,213]	8	hSpCas9	negative selection	1334337
98003687	98003710	8	-	26627737	RPE1	viability after 15 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	1.531601595192821	[867]	[632,783]	7	hSpCas9	negative selection	1334338
98007187	98007210	8	+	26627737	RPE1	viability after 15 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.69002209223557	[1614]	[734,738]	4	hSpCas9	negative selection	1334339
97888145	97888168	8	+	26627737	RPE1	viability after 18 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	-2.279773612545504	[565]	[0,63]	-8	hSpCas9	negative selection	1416649
97930963	97930986	8	+	26627737	RPE1	viability after 18 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	-0.8005105604053369	[1818]	[320,239]	-5	hSpCas9	negative selection	1416650
97941814	97941837	8	-	26627737	RPE1	viability after 18 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.05326989543577332	[1879]	[618,349]	0	hSpCas9	negative selection	1416651
97961481	97961504	8	-	26627737	RPE1	viability after 18 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	2.154315356407611	[237]	[268,303]	9	hSpCas9	negative selection	1416652
98003687	98003710	8	-	26627737	RPE1	viability after 18 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	1.6767380901196791	[867]	[672,829]	8	hSpCas9	negative selection	1416653
98007187	98007210	8	+	26627737	RPE1	viability after 18 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.6846544945405024	[1614]	[511,901]	4	hSpCas9	negative selection	1416654
97888145	97888168	8	+	26627737	HeLa	viability after 8 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	0.39245295876211217	[96]	[81,92,0]	3	hSpCas9	negative selection	1498964
97930963	97930986	8	+	26627737	HeLa	viability after 8 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	-0.03843421551463733	[1132]	[322,682,404]	0	hSpCas9	negative selection	1498965
97941814	97941837	8	-	26627737	HeLa	viability after 8 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.22753127849285626	[894]	[400,324,289]	-2	hSpCas9	negative selection	1498966
97961481	97961504	8	-	26627737	HeLa	viability after 8 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	0.4540788532777389	[262]	[215,134,133]	4	hSpCas9	negative selection	1498967
98003687	98003710	8	-	26627737	HeLa	viability after 8 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.13851415983506865	[584]	[157,438,220]	1	hSpCas9	negative selection	1498968
98007187	98007210	8	+	26627737	HeLa	viability after 8 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	1.0522974872468156	[477]	[444,597,265]	7	hSpCas9	negative selection	1498969
97888145	97888168	8	+	26627737	HeLa	viability after 12 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	0.6135333588636493	[96]	[7,74,97]	5	hSpCas9	negative selection	1581279
97930963	97930986	8	+	26627737	HeLa	viability after 12 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	-0.34437395485451017	[1132]	[148,434,508]	-3	hSpCas9	negative selection	1581280
97941814	97941837	8	-	26627737	HeLa	viability after 12 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	0.03847754133772141	[894]	[490,283,377]	0	hSpCas9	negative selection	1581281
97961481	97961504	8	-	26627737	HeLa	viability after 12 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	0.5303466808744984	[262]	[158,137,175]	4	hSpCas9	negative selection	1581282
98003687	98003710	8	-	26627737	HeLa	viability after 12 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	-0.07572673669882851	[584]	[136,186,365]	0	hSpCas9	negative selection	1581283
98007187	98007210	8	+	26627737	HeLa	viability after 12 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.3979320380430028	[477]	[180,255,341]	3	hSpCas9	negative selection	1581284
97888145	97888168	8	+	26627737	HeLa	viability after 15 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	0.7064296269818349	[96]	[99,86,0]	5	hSpCas9	negative selection	1663594
97930963	97930986	8	+	26627737	HeLa	viability after 15 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	-0.6178308897974025	[1132]	[287,335,275]	-5	hSpCas9	negative selection	1663595
97941814	97941837	8	-	26627737	HeLa	viability after 15 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.3766146499382198	[894]	[224,211,415]	-3	hSpCas9	negative selection	1663596
97961481	97961504	8	-	26627737	HeLa	viability after 15 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	0.5639628302294584	[262]	[325,56,83]	4	hSpCas9	negative selection	1663597
98003687	98003710	8	-	26627737	HeLa	viability after 15 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.5316228070024634	[584]	[421,250,359]	4	hSpCas9	negative selection	1663598
98007187	98007210	8	+	26627737	HeLa	viability after 15 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.8172806272676592	[477]	[288,244,507]	6	hSpCas9	negative selection	1663599
97888145	97888168	8	+	26627737	HeLa	viability after 18 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	0.6980332290765161	[96]	[67,69,0]	5	hSpCas9	negative selection	1745909
97930963	97930986	8	+	26627737	HeLa	viability after 18 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	-0.6262748445267612	[1132]	[185,282,275]	-5	hSpCas9	negative selection	1745910
97941814	97941837	8	-	26627737	HeLa	viability after 18 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.3861625604937118	[894]	[146,175,415]	-3	hSpCas9	negative selection	1745911
97961481	97961504	8	-	26627737	HeLa	viability after 18 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	0.608744271500743	[262]	[226,48,83]	5	hSpCas9	negative selection	1745912
98003687	98003710	8	-	26627737	HeLa	viability after 18 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.5414651257888271	[584]	[281,214,359]	4	hSpCas9	negative selection	1745913
98007187	98007210	8	+	26627737	HeLa	viability after 18 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.7849013744434901	[477]	[178,202,507]	6	hSpCas9	negative selection	1745914
97888145	97888168	8	+	26627737	HCT116	viability after 6 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	-0.2589045252081852	[157]	[3,29]	-1	hSpCas9	negative selection	1828224
97930963	97930986	8	+	26627737	HCT116	viability after 6 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	0.28483771938366975	[1488]	[299,276]	1	hSpCas9	negative selection	1828225
97941814	97941837	8	-	26627737	HCT116	viability after 6 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.38718246569810433	[1244]	[226,106]	-2	hSpCas9	negative selection	1828226
97961481	97961504	8	-	26627737	HCT116	viability after 6 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	1.2529166405804293	[617]	[52,329]	6	hSpCas9	negative selection	1828227
98003687	98003710	8	-	26627737	HCT116	viability after 6 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.452620844025275	[1384]	[607,126]	2	hSpCas9	negative selection	1828228
98007187	98007210	8	+	26627737	HCT116	viability after 6 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	1.2528004157893995	[1211]	[542,404]	6	hSpCas9	negative selection	1828229
97888145	97888168	8	+	26627737	HCT116	viability after 8 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	1.8300498537652081	[19]	[55,34,26]	9	hSpCas9	negative selection	1910539
97930963	97930986	8	+	26627737	HCT116	viability after 8 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	1.1041043123022434	[374]	[380,468,480]	8	hSpCas9	negative selection	1910540
97941814	97941837	8	-	26627737	HCT116	viability after 8 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.4443860795314596	[889]	[290,430,357]	-5	hSpCas9	negative selection	1910541
97961481	97961504	8	-	26627737	HCT116	viability after 8 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.4977801871693317	[387]	[190,199,64]	-5	hSpCas9	negative selection	1910542
98003687	98003710	8	-	26627737	HCT116	viability after 8 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.41553842964007537	[459]	[439,232,342]	4	hSpCas9	negative selection	1910543
98007187	98007210	8	+	26627737	HCT116	viability after 8 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.8966648184482523	[419]	[427,552,312]	7	hSpCas9	negative selection	1910544
97888145	97888168	8	+	26627737	HCT116	viability after 9 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	0.4445501422384035	[157]	[124,3]	3	hSpCas9	negative selection	1992854
97930963	97930986	8	+	26627737	HCT116	viability after 9 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	-0.20039731105126046	[1488]	[526,202]	-1	hSpCas9	negative selection	1992855
97941814	97941837	8	-	26627737	HCT116	viability after 9 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	0.29136983705163333	[1244]	[560,284]	2	hSpCas9	negative selection	1992856
97961481	97961504	8	-	26627737	HCT116	viability after 9 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.4130108086751316	[617]	[52,179]	-3	hSpCas9	negative selection	1992857
98003687	98003710	8	-	26627737	HCT116	viability after 9 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	-0.20952427304186605	[1384]	[392,261]	-1	hSpCas9	negative selection	1992858
98007187	98007210	8	+	26627737	HCT116	viability after 9 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	-0.6253009143468227	[1211]	[101,294]	-4	hSpCas9	negative selection	1992859
97888145	97888168	8	+	26627737	HCT116	viability after 12 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	1.28890953807075	[19]	[5,34,37]	8	hSpCas9	negative selection	2075169
97930963	97930986	8	+	26627737	HCT116	viability after 12 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	1.1832348563282877	[374]	[351,407,589]	8	hSpCas9	negative selection	2075170
97941814	97941837	8	-	26627737	HCT116	viability after 12 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.3380624349510384	[889]	[397,345,362]	-4	hSpCas9	negative selection	2075171
97961481	97961504	8	-	26627737	HCT116	viability after 12 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.45837502178220946	[387]	[144,209,91]	-5	hSpCas9	negative selection	2075172
98003687	98003710	8	-	26627737	HCT116	viability after 12 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.48086293547641634	[459]	[257,333,426]	4	hSpCas9	negative selection	2075173
98007187	98007210	8	+	26627737	HCT116	viability after 12 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.7203988088724641	[419]	[317,362,413]	6	hSpCas9	negative selection	2075174
97888145	97888168	8	+	26627737	HCT116	viability after 15 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	0.26062263549529785	[19]	[19,4,16]	2	hSpCas9	negative selection	2157484
97930963	97930986	8	+	26627737	HCT116	viability after 15 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	1.054878446916111	[374]	[386,424,521]	8	hSpCas9	negative selection	2157485
97941814	97941837	8	-	26627737	HCT116	viability after 15 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.3835220608545069	[889]	[413,361,401]	-4	hSpCas9	negative selection	2157486
97961481	97961504	8	-	26627737	HCT116	viability after 15 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.22942690250934175	[387]	[161,149,253]	-2	hSpCas9	negative selection	2157487
98003687	98003710	8	-	26627737	HCT116	viability after 15 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.3077022050874645	[459]	[283,388,302]	3	hSpCas9	negative selection	2157488
98007187	98007210	8	+	26627737	HCT116	viability after 15 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.8058813613290995	[419]	[380,450,427]	7	hSpCas9	negative selection	2157489
97888145	97888168	8	+	26627737	HCT116	viability after 18 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	0.38466041988519795	[19]	[1,32,0]	3	hSpCas9	negative selection	2239799
97930963	97930986	8	+	26627737	HCT116	viability after 18 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	1.2830189845984394	[374]	[253,513,555]	8	hSpCas9	negative selection	2239800
97941814	97941837	8	-	26627737	HCT116	viability after 18 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.1902542031736052	[889]	[452,228,462]	-2	hSpCas9	negative selection	2239801
97961481	97961504	8	-	26627737	HCT116	viability after 18 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	0.17602214846899772	[387]	[105,201,333]	1	hSpCas9	negative selection	2239802
98003687	98003710	8	-	26627737	HCT116	viability after 18 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.8725045456466721	[459]	[299,360,570]	7	hSpCas9	negative selection	2239803
98007187	98007210	8	+	26627737	HCT116	viability after 18 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.46439018786952413	[419]	[204,314,319]	4	hSpCas9	negative selection	2239804
97980655	97980678	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGGGAATCGCTTGAACCCAGG	MATN2	ENSG00000132561	1.265513798769316	[1,0]	[0,0]	5	dCas9-VP64	positive selection	2393028
97934539	97934562	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	AACCAAAAAGTATCTGAGACAAG	MATN2	ENSG00000132561	0.8269210336232619	[39,55]	[18,16]	3	dCas9-VP64	positive selection	2395367
97884739	97884762	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGTCTCGCTGTCGCCCAGGCAGG	MATN2	ENSG00000132561	0.8346262078071658	[10,1]	[2,1]	3	dCas9-VP64	positive selection	2416331
97877243	97877266	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGGCGGGCGGATCATCTGAGG	MATN2	ENSG00000132561	1.1682084451349461	[40,6]	[12,9]	4	dCas9-VP64	positive selection	2431567
97960097	97960120	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGCGTGCCACCACGCCAAG	MATN2	ENSG00000132561	2.643483847646077	[13,290]	[2,439]	8	dCas9-VP64	positive selection	2433839
97909807	97909830	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCGCTCTGTCGCCCCGG	MATN2	ENSG00000132561	-0.5315818005101806	[14,129]	[5,15]	-3	dCas9-VP64	positive selection	2444240
97870490	97870513	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTTTAGCTCTTGTTGCCCAGG	MATN2	ENSG00000132561	0.6253677242507178	[47,72]	[2,37]	2	dCas9-VP64	positive selection	2456565
97868988	97869011	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGACACCCCTCCTTCCGCCCGG	MATN2	ENSG00000132561	2.32715073909844	[30,43]	[21,62]	7	dCas9-VP64	positive selection	2457246
97868903	97868926	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCCCGGGAGCTGGGCACTCTGG	MATN2	ENSG00000132561	3.6693169679463065	[176,217]	[10,1143]	9	dCas9-VP64	positive selection	2457247
97868929	97868952	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGAGGGCGGCCCCACCCTGTGG	MATN2	ENSG00000132561	2.0529219383012682	[36,19]	[47,0]	7	dCas9-VP64	positive selection	2457248
97877128	97877151	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCGAGTAGCTGGGACTATAAG	MATN2	ENSG00000132561	-1.652200712598355	[99,148]	[10,4]	-8	dCas9-VP64	positive selection	2460201
97980655	97980678	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGGGAATCGCTTGAACCCAGG	MATN2	ENSG00000132561	0.4069448835878763	[149,7]	[63,7]	3	dCas9-VP64	positive selection	2488283
97934539	97934562	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	AACCAAAAAGTATCTGAGACAAG	MATN2	ENSG00000132561	4.518269774264655	[235,157]	[3047,16]	9	dCas9-VP64	positive selection	2490622
97884739	97884762	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGTCTCGCTGTCGCCCAGGCAGG	MATN2	ENSG00000132561	-1.711674582430177	[43,184]	[8,12]	-9	dCas9-VP64	positive selection	2511586
97877243	97877266	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGGCGGGCGGATCATCTGAGG	MATN2	ENSG00000132561	1.094181115939585	[31,116]	[73,29]	7	dCas9-VP64	positive selection	2526822
97960097	97960120	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGCGTGCCACCACGCCAAG	MATN2	ENSG00000132561	0.7224579133223353	[33,61]	[16,32]	5	dCas9-VP64	positive selection	2529094
97909807	97909830	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCGCTCTGTCGCCCCGG	MATN2	ENSG00000132561	0.35722745049512583	[51,32]	[17,15]	3	dCas9-VP64	positive selection	2539495
97870490	97870513	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTTTAGCTCTTGTTGCCCAGG	MATN2	ENSG00000132561	0.32357428037623304	[183,171]	[128,18]	2	dCas9-VP64	positive selection	2551820
97868988	97869011	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGACACCCCTCCTTCCGCCCGG	MATN2	ENSG00000132561	1.082814655374413	[206,176]	[137,128]	7	dCas9-VP64	positive selection	2552501
97868903	97868926	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCCCGGGAGCTGGGCACTCTGG	MATN2	ENSG00000132561	0.9789378569554156	[48,68]	[19,53]	6	dCas9-VP64	positive selection	2552502
97868929	97868952	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGAGGGCGGCCCCACCCTGTGG	MATN2	ENSG00000132561	0.7406452048892715	[14,27]	[14,7]	5	dCas9-VP64	positive selection	2552503
97877128	97877151	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCGAGTAGCTGGGACTATAAG	MATN2	ENSG00000132561	-0.7864950913442017	[144,106]	[22,23]	-7	dCas9-VP64	positive selection	2555456
98007143	98007166	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.3720701086844651	[3,3]	[4,4]	7	hSpCas9	positive selection	3001423
97931294	97931317	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.2891458029152802	[3,2]	[0,2]	-4	hSpCas9	positive selection	3001424
98007143	98007166	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.29896411863739225	[3,3]	[4,2]	5	hSpCas9	positive selection	3069281
97931294	97931317	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.3097422031205674	[3,3]	[1,1]	-5	hSpCas9	positive selection	3069282
97978987	97979010		-	24336571	A375	resistance to PLX after 7 days	CTTGTGCACGTTTTTTTATCTGG	MATN2	ENSG00000132561	0.018120995793851957	[41,41]	[40,42]	0	hSpCas9	positive selection	3126571
97978951	97978974		+	24336571	A375	resistance to PLX after 7 days	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.17565475361838168	[34,39]	[33,32]	-5	hSpCas9	positive selection	3126572
97978987	97979010		-	24336571	A375	resistance to PLX after 14 days	CTTGTGCACGTTTTTTTATCTGG	MATN2	ENSG00000132561	-0.23614822195632312	[40,42]	[14,17]	-3	hSpCas9	positive selection	3184364
97978951	97978974		+	24336571	A375	resistance to PLX after 14 days	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.5897144505009222	[44,44]	[13,12]	-7	hSpCas9	positive selection	3184365
97978987	97979010		-	24336571	A375	viability after 7 days	CTTGTGCACGTTTTTTTATCTGG	MATN2	ENSG00000132561	0.5766672983585803	[28]	[41,41]	8	hSpCas9	negative selection	3242157
97978951	97978974		+	24336571	A375	viability after 7 days	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.49105226075848707	[27]	[34,39]	7	hSpCas9	negative selection	3242158
97978987	97979010		-	24336571	A375	viability after 14 days	CTTGTGCACGTTTTTTTATCTGG	MATN2	ENSG00000132561	0.5987158847402096	[28]	[40,42]	7	hSpCas9	negative selection	3299950
97978951	97978974		+	24336571	A375	viability after 14 days	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.7665490315273622	[27]	[44,44]	8	hSpCas9	negative selection	3299951
97978911	97978934	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	-1.202105407191462	[351,351]	[0,0]	-7	hSpCas9	positive selection	3378621
97978951	97978974	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.10022579317224871	[163,163]	[0,0]	0	hSpCas9	positive selection	3378622
97888234	97888257	8	-	26780180	HT29	viability (Avana library 4 designs)	GCACCACCACTCACCCAGAAGGG	MATN2	ENSG00000132561	1.5714426204553	[]	[]	6	hSpCas9	negative selection	3439121
98007142	98007165	8	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	-0.332691385099189	[]	[]	-5	hSpCas9	negative selection	3439122
97931294	97931317	8	-	26780180	HT29	viability (Avana library 4 designs)	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	1.33383418808359	[]	[]	5	hSpCas9	negative selection	3439123
97978894	97978917	8	+	26780180	HT29	viability (Avana library 4 designs)	TACTGTGCCTCAGAAAACCACGG	MATN2	ENSG00000132561	1.09701937281292	[]	[]	4	hSpCas9	negative selection	3439124
97978894	97978917	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	TACTGTGCCTCAGAAAACCACGG	MATN2	ENSG00000132561	-0.191780789067018	[]	[]	0	hSpCas9	negative selection	3528708
97888234	97888257	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACCACCACTCACCCAGAAGGG	MATN2	ENSG00000132561	-2.56585524882942	[]	[]	-3	hSpCas9	negative selection	3528709
98007142	98007165	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	2.75364731725075	[]	[]	4	hSpCas9	negative selection	3528710
97931294	97931317	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	1.19009698737417	[]	[]	1	hSpCas9	negative selection	3528711
97978894	97978917	8	+	26780180	A375	viability (Avana lentiGuide)	TACTGTGCCTCAGAAAACCACGG	MATN2	ENSG00000132561	-2.34290422732353	[]	[]	-4	hSpCas9	negative selection	3637367
97888234	97888257	8	-	26780180	A375	viability (Avana lentiGuide)	GCACCACCACTCACCCAGAAGGG	MATN2	ENSG00000132561	-3.11656984159128	[]	[]	-5	hSpCas9	negative selection	3637368
98007142	98007165	8	+	26780180	A375	viability (Avana lentiGuide)	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	-5.9030630397059	[]	[]	-8	hSpCas9	negative selection	3637369
97931294	97931317	8	-	26780180	A375	viability (Avana lentiGuide)	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	6.62572954940311	[]	[]	5	hSpCas9	negative selection	3637370
97978894	97978917	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TACTGTGCCTCAGAAAACCACGG	MATN2	ENSG00000132561	-0.3754678061697736	[5]	[4,3]	-5	hSpCas9	positive selection	3746026
97888234	97888257	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACCACCACTCACCCAGAAGGG	MATN2	ENSG00000132561	-0.601461411054666	[3]	[3,0]	-7	hSpCas9	positive selection	3746027
98007142	98007165	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.0460865383926541	[5]	[5,4]	1	hSpCas9	positive selection	3746028
97931294	97931317	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.1691465462744834	[5]	[5,5]	4	hSpCas9	positive selection	3746029
97978894	97978917	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TACTGTGCCTCAGAAAACCACGG	MATN2	ENSG00000132561	0.19731175618843586	[5]	[6,4]	5	hSpCas9	positive selection	3854633
97888234	97888257	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACCACCACTCACCCAGAAGGG	MATN2	ENSG00000132561	-0.4544826548162193	[5]	[2,2]	-5	hSpCas9	positive selection	3854634
98007142	98007165	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.27870414518286657	[5]	[6,5]	7	hSpCas9	positive selection	3854635
97931294	97931317	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.20340214123747313	[4]	[3,3]	-3	hSpCas9	positive selection	3854636
97978911	97978934	8	-	26780180	A375	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	1.38140542271631	[]	[]	7	hSpCas9	negative selection	3960146
97978951	97978974	8	+	26780180	A375	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.728277061647443	[]	[]	2	hSpCas9	negative selection	3960147
97978911	97978934	8	-	26780180	HT29	viability (GeCKOv2 library)	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.970104325337752	[]	[]	4	hSpCas9	negative selection	4068112
97978951	97978974	8	+	26780180	HT29	viability (GeCKOv2 library)	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	1.4344201595647	[]	[]	7	hSpCas9	negative selection	4068113
97978987	97979010	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTGTGCACGTTTTTTTATCTGG	MATN2	ENSG00000132561	0.19395524401562364	[5]	[3,3]	5	hSpCas9	positive selection	4150854
97978951	97978974	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.21769524615966163	[4]	[3,3]	5	hSpCas9	positive selection	4150856
97978987	97979010	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTGTGCACGTTTTTTTATCTGG	MATN2	ENSG00000132561	0.3367266238722432	[4]	[4,3,3,0]	2	hSpCas9	positive selection	4214876
97978951	97978974	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	1.1883811129532618	[5]	[5,6,5,4]	8	hSpCas9	positive selection	4214878
97978911	97978934	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.1207414675568679	[3]	[3,2]	2	hSpCas9	positive selection	4346347
97978951	97978974	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.09391832699527398	[2]	[2,1]	2	hSpCas9	positive selection	4346349
97931094	97931116	8	+	27760321	OCIAML3	viability	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	-0.5745548820939821	[456,409]	[173,296]	-5	hSpCas9	negative selection	4417028
97931230	97931252	8	-	27760321	OCIAML3	viability	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	0.03508691380369097	[560,428]	[265,559]	0	hSpCas9	negative selection	4417029
97931294	97931316	8	-	27760321	OCIAML3	viability	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.7143226277186541	[808,158]	[475,735]	8	hSpCas9	negative selection	4417030
97931352	97931374	8	+	27760321	OCIAML3	viability	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	0.3807336821590518	[537,463]	[371,686]	4	hSpCas9	negative selection	4417031
98003696	98003718	8	+	27760321	OCIAML3	viability	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.5787410302117604	[419,321]	[344,540]	7	hSpCas9	negative selection	4417032
97931094	97931116	8	+	27760321	OCIAML2	viability	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	-0.3895262029039437	[456,409]	[209,342]	-4	hSpCas9	negative selection	4500491
97931230	97931252	8	-	27760321	OCIAML2	viability	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	-0.1542698837319622	[560,428]	[325,397]	-2	hSpCas9	negative selection	4500492
97931294	97931316	8	-	27760321	OCIAML2	viability	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.33569496429836143	[808,158]	[436,509]	4	hSpCas9	negative selection	4500493
97931352	97931374	8	+	27760321	OCIAML2	viability	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	0.3759949014342837	[537,463]	[555,482]	5	hSpCas9	negative selection	4500494
98003696	98003718	8	+	27760321	OCIAML2	viability	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.07094988543107461	[419,321]	[289,342]	0	hSpCas9	negative selection	4500495
97931094	97931116	8	+	27760321	MV411	viability	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	0.4032030665234984	[456,409]	[456,258]	3	hSpCas9	negative selection	4583954
97931230	97931252	8	-	27760321	MV411	viability	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	-0.004521032639615674	[560,428]	[243,441]	0	hSpCas9	negative selection	4583955
97931294	97931316	8	-	27760321	MV411	viability	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	1.2871543723001206	[808,158]	[569,992]	8	hSpCas9	negative selection	4583956
97931352	97931374	8	+	27760321	MV411	viability	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	1.0186474923316744	[537,463]	[862,374]	7	hSpCas9	negative selection	4583957
98003696	98003718	8	+	27760321	MV411	viability	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.7496310322190471	[419,321]	[559,180]	5	hSpCas9	negative selection	4583958
97931094	97931116	8	+	27760321	HL60	viability	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	-0.4674110233869798	[456,409]	[282,226]	-5	hSpCas9	negative selection	4667417
97931230	97931252	8	-	27760321	HL60	viability	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	0.21834141176232727	[560,428]	[377,560]	2	hSpCas9	negative selection	4667418
97931294	97931316	8	-	27760321	HL60	viability	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	1.1077618117088746	[808,158]	[1052,547]	9	hSpCas9	negative selection	4667419
97931352	97931374	8	+	27760321	HL60	viability	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	-0.6415658581110272	[537,463]	[314,204]	-6	hSpCas9	negative selection	4667420
98003696	98003718	8	+	27760321	HL60	viability	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.5781435637982579	[419,321]	[449,447]	7	hSpCas9	negative selection	4667421
97931094	97931116	8	+	27760321	HT1080	viability	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	-0.3599831298345315	[409,319]	[108,117]	-2	hSpCas9	negative selection	4750880
97931230	97931252	8	-	27760321	HT1080	viability	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	0.3792394927671846	[428,334]	[164,233]	2	hSpCas9	negative selection	4750881
97931294	97931316	8	-	27760321	HT1080	viability	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	1.737815113934045	[158,123]	[187,187]	8	hSpCas9	negative selection	4750882
97931352	97931374	8	+	27760321	HT1080	viability	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	0.5675798988354432	[463,361]	[176,316]	3	hSpCas9	negative selection	4750883
98003696	98003718	8	+	27760321	HT1080	viability	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	1.3304601174973496	[321,250]	[265,309]	7	hSpCas9	negative selection	4750884
97931094	97931116	8	+	27760321	HT29	viability after 7 days	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	0.16791268922713137	[409,319]	[690,378,533]	2	hSpCas9	negative selection	4834343
97931230	97931252	8	-	27760321	HT29	viability after 7 days	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	-0.1711263162189891	[428,334]	[544,483,298]	-3	hSpCas9	negative selection	4834344
97931294	97931316	8	-	27760321	HT29	viability after 7 days	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.8175315977449252	[158,123]	[230,377,338]	9	hSpCas9	negative selection	4834345
97931352	97931374	8	+	27760321	HT29	viability after 7 days	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	-0.2127749148629859	[463,361]	[350,371,629]	-3	hSpCas9	negative selection	4834346
98003696	98003718	8	+	27760321	HT29	viability after 7 days	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.13783654568849651	[321,250]	[404,463,347]	2	hSpCas9	negative selection	4834347
97931094	97931116	8	+	27760321	HT29	viability after 25 days	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	-0.6131517725153465	[409,319]	[351,219,236]	-5	hSpCas9	negative selection	4917806
97931230	97931252	8	-	27760321	HT29	viability after 25 days	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	-0.2221698215863036	[428,334]	[376,353,392]	-2	hSpCas9	negative selection	4917807
97931294	97931316	8	-	27760321	HT29	viability after 25 days	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	1.89887047561833	[158,123]	[506,455,879]	9	hSpCas9	negative selection	4917808
97931352	97931374	8	+	27760321	HT29	viability after 25 days	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	0.26386962200947073	[463,361]	[454,617,640]	2	hSpCas9	negative selection	4917809
98003696	98003718	8	+	27760321	HT29	viability after 25 days	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.7371376272080208	[321,250]	[479,773,367]	8	hSpCas9	negative selection	4917810
97931094	97931116	8	+	27760321	HT29	viability after 22 days	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	-0.43521440147803364	[409,319]	[212,401,323]	-4	hSpCas9	negative selection	5001269
97931230	97931252	8	-	27760321	HT29	viability after 22 days	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	0.09519846125498527	[428,334]	[438,412,564]	0	hSpCas9	negative selection	5001270
97931294	97931316	8	-	27760321	HT29	viability after 22 days	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	1.4254993198347745	[158,123]	[465,450,399]	9	hSpCas9	negative selection	5001271
97931352	97931374	8	+	27760321	HT29	viability after 22 days	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	0.20359918133804245	[463,361]	[408,504,740]	2	hSpCas9	negative selection	5001272
98003696	98003718	8	+	27760321	HT29	viability after 22 days	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.8523926650501499	[321,250]	[654,672,462]	8	hSpCas9	negative selection	5001273
97931094	97931116	8	+	27760321	HT29	viability after 19 days	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	0.015492217658177876	[409,319]	[632,241,412]	0	hSpCas9	negative selection	5084732
97931230	97931252	8	-	27760321	HT29	viability after 19 days	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	-1.070706640123842	[428,334]	[284,140,205]	-6	hSpCas9	negative selection	5084733
97931294	97931316	8	-	27760321	HT29	viability after 19 days	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	1.9647672464151056	[158,123]	[579,752,558]	9	hSpCas9	negative selection	5084734
97931352	97931374	8	+	27760321	HT29	viability after 19 days	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	0.3137902170526931	[463,361]	[489,627,630]	3	hSpCas9	negative selection	5084735
98003696	98003718	8	+	27760321	HT29	viability after 19 days	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.6564287891720835	[321,250]	[531,487,529]	6	hSpCas9	negative selection	5084736
97931094	97931116	8	+	27760321	HT29	viability after 16 days	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	-0.01102796288017897	[409,319]	[342,359,507]	0	hSpCas9	negative selection	5168195
97931230	97931252	8	-	27760321	HT29	viability after 16 days	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	-0.22722971546231946	[428,334]	[313,305,471]	-3	hSpCas9	negative selection	5168196
97931294	97931316	8	-	27760321	HT29	viability after 16 days	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	2.0511754503864306	[158,123]	[854,767,360]	9	hSpCas9	negative selection	5168197
97931352	97931374	8	+	27760321	HT29	viability after 16 days	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	-0.19931721314324086	[463,361]	[320,269,611]	-2	hSpCas9	negative selection	5168198
98003696	98003718	8	+	27760321	HT29	viability after 16 days	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.14138734324569893	[321,250]	[361,287,412]	1	hSpCas9	negative selection	5168199
97931094	97931116	8	+	27760321	HT29	viability after 13 days	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	-0.005123951280121674	[409,319]	[619,320,329]	0	hSpCas9	negative selection	5251658
97931230	97931252	8	-	27760321	HT29	viability after 13 days	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	-0.4458439830193257	[428,334]	[349,164,452]	-5	hSpCas9	negative selection	5251659
97931294	97931316	8	-	27760321	HT29	viability after 13 days	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	1.3366837486228451	[158,123]	[277,397,558]	9	hSpCas9	negative selection	5251660
97931352	97931374	8	+	27760321	HT29	viability after 13 days	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	0.1634117950752983	[463,361]	[549,512,545]	2	hSpCas9	negative selection	5251661
98003696	98003718	8	+	27760321	HT29	viability after 13 days	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.4181153899594113	[321,250]	[676,404,260]	5	hSpCas9	negative selection	5251662
97931094	97931116	8	+	27760321	HT29	viability after 10 days	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	-0.49564965837748154	[409,319]	[370,389,212]	-6	hSpCas9	negative selection	5335121
97931230	97931252	8	-	27760321	HT29	viability after 10 days	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	-0.9433276019084839	[428,334]	[273,214,253]	-7	hSpCas9	negative selection	5335122
97931294	97931316	8	-	27760321	HT29	viability after 10 days	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	1.7646834476503568	[158,123]	[755,634,414]	9	hSpCas9	negative selection	5335123
97931352	97931374	8	+	27760321	HT29	viability after 10 days	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	-0.1772559937577954	[463,361]	[515,328,517]	-2	hSpCas9	negative selection	5335124
98003696	98003718	8	+	27760321	HT29	viability after 10 days	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.16897098688003379	[321,250]	[396,377,429]	2	hSpCas9	negative selection	5335125
97931094	97931116	8	+	27760321	MOLM13	viability	GAGTGGGCCTGCTCCAATATGG	MATN2	ENSG00000132561	-0.6357470139504617	[456,409]	[328,10]	-4	hSpCas9	negative selection	5418584
97931230	97931252	8	-	27760321	MOLM13	viability	TGCGATGTTCAGGGCATACTGG	MATN2	ENSG00000132561	-0.1909419833263448	[560,428]	[238,245]	-1	hSpCas9	negative selection	5418585
97931294	97931316	8	-	27760321	MOLM13	viability	TCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.5438434286509352	[808,158]	[377,376]	4	hSpCas9	negative selection	5418586
97931352	97931374	8	+	27760321	MOLM13	viability	CTGCTAAGGCACGGGACACGGG	MATN2	ENSG00000132561	0.6897733072235711	[537,463]	[337,553]	5	hSpCas9	negative selection	5418587
98003696	98003718	8	+	27760321	MOLM13	viability	GAGCATGAGTGCGTCAACATGG	MATN2	ENSG00000132561	0.15552214954007876	[419,321]	[501,0]	1	hSpCas9	negative selection	5418588
97869094	97869117	8	+	27661255	K562	viability	GAGCGCTCTGGGATGGGACTTGG	MATN2	ENSG00000132561	-0.388587464952141	[538,498]	[328,306]	-7	dCas9-KRAB	negative selection	5492456
97869109	97869132	8	+	27661255	K562	viability	GGACTTGGAGCAAGCGGCGGCGG	MATN2	ENSG00000132561	0.09718579782277874	[943,700]	[793,631]	3	dCas9-KRAB	negative selection	5492457
97869222	97869245	8	+	27661255	K562	viability	GAGGCCGACGAGGAAGACCCGGG	MATN2	ENSG00000132561	0.22698848455755424	[680,878]	[767,689]	7	dCas9-KRAB	negative selection	5492458
97888136	97888159	8	-	27661255	K562	viability	GGAGGAGGACGATCTGTCCGAGG	MATN2	ENSG00000132561	0.1334846570982845	[517,439]	[441,402]	4	dCas9-KRAB	negative selection	5492459
97978911	97978934	8	-	27260156	BXPC3	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.21940456047630164	[697]	[827,733,889,964]	5	hSpCas9	negative selection	5618807
97978951	97978974	8	+	27260156	BXPC3	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.03321028921703306	[387]	[312,340,474,477]	0	hSpCas9	negative selection	5618809
97978911	97978934	8	-	27260156	A673	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.40529845797637776	[697]	[1261,1050,1010,1134]	8	hSpCas9	negative selection	5740058
97978951	97978974	8	+	27260156	A673	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.10108165728240423	[387]	[677,454,424,459]	2	hSpCas9	negative selection	5740060
97978911	97978934	8	-	27260156	A375	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.40737302484611715	[697]	[1407,1007,1203,734]	6	hSpCas9	negative selection	5861309
97978951	97978974	8	+	27260156	A375	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.25350837447504554	[387]	[581,453,587,524]	3	hSpCas9	negative selection	5861311
97978911	97978934	8	-	27260156	COLO741	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.22568860990426765	[697]	[1113,1098,927]	5	hSpCas9	negative selection	5982560
97978951	97978974	8	+	27260156	COLO741	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.21902635565400236	[387]	[606,655,476]	4	hSpCas9	negative selection	5982562
97978911	97978934	8	-	27260156	CAL120	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.27834763770523907	[697]	[995,1314,843]	4	hSpCas9	negative selection	6103811
97978951	97978974	8	+	27260156	CAL120	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.4608285062280156	[387]	[760,536,708]	7	hSpCas9	negative selection	6103813
97978911	97978934	8	-	27260156	CADOES1	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.28203031957858504	[697]	[785,914,887,559]	5	hSpCas9	negative selection	6225062
97978951	97978974	8	+	27260156	CADOES1	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.26909064441745806	[387]	[596,552,340,240]	4	hSpCas9	negative selection	6225064
97978911	97978934	8	-	27260156	EWS502	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.3514343058729976	[697]	[745,766,1076,1232]	6	hSpCas9	negative selection	6346313
97978951	97978974	8	+	27260156	EWS502	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.20218792380601416	[387]	[346,611,431,509]	3	hSpCas9	negative selection	6346315
97978911	97978934	8	-	27260156	EW8	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.3192657204097107	[697]	[806,839,624,574]	6	hSpCas9	negative selection	6467564
97978951	97978974	8	+	27260156	EW8	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.14584786076257059	[387]	[337,358,314,382]	2	hSpCas9	negative selection	6467566
97978911	97978934	8	-	27260156	CORL105	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.1648659086474379	[697]	[903,951,1072,758]	3	hSpCas9	negative selection	6588815
97978951	97978974	8	+	27260156	CORL105	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.07454617260999144	[387]	[413,407,698,425]	1	hSpCas9	negative selection	6588817
97978911	97978934	8	-	27260156	HS294T	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.8157958242736524	[697]	[356,943,287,270]	9	hSpCas9	negative selection	6710066
97978951	97978974	8	+	27260156	HS294T	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.13389378353730996	[387]	[76,164,93,230]	-2	hSpCas9	negative selection	6710068
97978911	97978934	8	-	27260156	HCC44	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.3556585124073741	[697]	[1019,730,1515,896]	6	hSpCas9	negative selection	6831317
97978951	97978974	8	+	27260156	HCC44	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.25639333766490036	[387]	[511,333,663,628]	4	hSpCas9	negative selection	6831319
97978911	97978934	8	-	27260156	G402	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.08759023696096757	[697]	[952,1265,934,509]	1	hSpCas9	negative selection	6952568
97978951	97978974	8	+	27260156	G402	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.22455904653864323	[387]	[458,268,526,365]	-3	hSpCas9	negative selection	6952570
97978911	97978934	8	-	27260156	L33	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	-0.03563961905394453	[697]	[633,300,419,687]	-1	hSpCas9	negative selection	7073819
97978951	97978974	8	+	27260156	L33	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.23899239372694794	[387]	[328,212,266,559]	5	hSpCas9	negative selection	7073821
97978911	97978934	8	-	27260156	K562	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.008651602515562296	[697]	[478,759,987,296]	0	hSpCas9	negative selection	7195070
97978951	97978974	8	+	27260156	K562	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.5061419448988467	[387]	[469,187,943,350]	6	hSpCas9	negative selection	7195072
97978911	97978934	8	-	27260156	HT29	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.3327379785810801	[697]	[1213,1060,1111,909]	6	hSpCas9	negative selection	7316321
97978951	97978974	8	+	27260156	HT29	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.14652638049464822	[387]	[448,498,430,340]	-3	hSpCas9	negative selection	7316323
97978911	97978934	8	-	27260156	MHHES1	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.13843233793028542	[697]	[942,1035,1015,548]	2	hSpCas9	negative selection	7437572
97978951	97978974	8	+	27260156	MHHES1	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.12671804021003	[387]	[471,563,275,569]	2	hSpCas9	negative selection	7437574
97978911	97978934	8	-	27260156	MEWO	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.2762805509165591	[697]	[1023,494,899]	6	hSpCas9	negative selection	7558823
97978951	97978974	8	+	27260156	MEWO	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.11380525168032468	[387]	[404,291,322]	-2	hSpCas9	negative selection	7558825
97978911	97978934	8	-	27260156	LNCAPCLONEFGC	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.1177268687360512	[697]	[731,566,741,717]	1	hSpCas9	negative selection	7680074
97978951	97978974	8	+	27260156	LNCAPCLONEFGC	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.18138575769580828	[387]	[500,208,630,297]	3	hSpCas9	negative selection	7680076
97978911	97978934	8	-	27260156	PANC0327	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.23846892160958966	[697]	[882,644,589,830]	3	hSpCas9	negative selection	7801325
97978951	97978974	8	+	27260156	PANC0327	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.4022541645692479	[387]	[556,325,515,447]	6	hSpCas9	negative selection	7801327
97978911	97978934	8	-	27260156	NCIH2009	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.2606506043860616	[697]	[1720,960,933]	3	hSpCas9	negative selection	7922576
97978951	97978974	8	+	27260156	NCIH2009	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.18019384627068563	[387]	[892,542,461]	2	hSpCas9	negative selection	7922578
97978911	97978934	8	-	27260156	NCIH1373	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	-0.1384092735302455	[697]	[723,659,1033,105]	-1	hSpCas9	negative selection	8043827
97978951	97978974	8	+	27260156	NCIH1373	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.05815200416954003	[387]	[722,328,385,111]	0	hSpCas9	negative selection	8043829
97978911	97978934	8	-	27260156	PATU8902	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.3393040532237528	[697]	[1362,1350,1048,1186]	3	hSpCas9	negative selection	8165078
97978951	97978974	8	+	27260156	PATU8902	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.32438310239804347	[387]	[534,802,571,839]	3	hSpCas9	negative selection	8165080
97978911	97978934	8	-	27260156	PANC1	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	-0.0673416848542433	[697]	[739,630,490,445]	-1	hSpCas9	negative selection	8286329
97978951	97978974	8	+	27260156	PANC1	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.07169063281555199	[387]	[264,345,423,359]	1	hSpCas9	negative selection	8286331
97978911	97978934	8	-	27260156	PANC0813	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	-0.23562741039480462	[697]	[640,673,690,768]	-4	hSpCas9	negative selection	8407580
97978951	97978974	8	+	27260156	PANC0813	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.10198293871623038	[387]	[605,574,439,352]	1	hSpCas9	negative selection	8407582
97978911	97978934	8	-	27260156	RDES	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.17781349432488258	[697]	[765,775,1026,1114]	3	hSpCas9	negative selection	8528831
97978951	97978974	8	+	27260156	RDES	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.03337426555879264	[387]	[355,406,517,579]	0	hSpCas9	negative selection	8528833
97978911	97978934	8	-	27260156	PC3	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.2787869103286513	[697]	[489,847,1427,918]	6	hSpCas9	negative selection	8650082
97978951	97978974	8	+	27260156	PC3	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.21875897498272004	[387]	[266,678,680,278]	5	hSpCas9	negative selection	8650084
97978911	97978934	8	-	27260156	PATU8988T	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.07830967325685945	[697]	[768,708,782,574]	1	hSpCas9	negative selection	8771333
97978951	97978974	8	+	27260156	PATU8988T	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.03530315829525521	[387]	[249,314,372,533]	0	hSpCas9	negative selection	8771335
97978911	97978934	8	-	27260156	T47D	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.3732590309315048	[697]	[1163,1064,932,1051]	7	hSpCas9	negative selection	8892584
97978951	97978974	8	+	27260156	T47D	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.03643483867817013	[387]	[399,468,509,473]	0	hSpCas9	negative selection	8892586
97978911	97978934	8	-	27260156	SU8686	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	-0.12161678791389041	[697]	[688,504,672,693]	-2	hSpCas9	negative selection	9013835
97978951	97978974	8	+	27260156	SU8686	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.06787899358162996	[387]	[415,258,349,463]	-1	hSpCas9	negative selection	9013837
97978911	97978934	8	-	27260156	SKES1	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.2962372516217927	[697]	[1160,785,803,711]	6	hSpCas9	negative selection	9135086
97978951	97978974	8	+	27260156	SKES1	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	0.2231877983653463	[387]	[461,635,524,228]	5	hSpCas9	negative selection	9135088
97978911	97978934	8	-	27260156	TOV112D	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.21105619010246524	[697]	[823,879,480,1061]	4	hSpCas9	negative selection	9256337
97978951	97978974	8	+	27260156	TOV112D	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.3230639612650926	[387]	[316,350,291,292]	-6	hSpCas9	negative selection	9256339
97978911	97978934	8	-	27260156	TC71	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.2718339337449621	[697]	[962,1001,808,836]	6	hSpCas9	negative selection	9377588
97978951	97978974	8	+	27260156	TC71	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.1054890297322908	[387]	[362,436,337,411]	-3	hSpCas9	negative selection	9377590
97978911	97978934	8	-	27260156	TC32	viability	CACACTCATGTTCACATCCGTGG	MATN2	ENSG00000132561	0.17813733673750132	[697]	[629,598,981,827]	3	hSpCas9	negative selection	9498839
97978951	97978974	8	+	27260156	TC32	viability	TACCTTTGCCAGTGCCATGAAGG	MATN2	ENSG00000132561	-0.1725540355230133	[387]	[329,189,500,335]	-3	hSpCas9	negative selection	9498841
97888145	97888168	8	+	27869803	HPAFII	viability after 27 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	2.516181532160208	[11]	[46,26,NaN]	9	hSpCas9	negative selection	9603548
97930963	97930986	8	+	27869803	HPAFII	viability after 27 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	0.3689089899373168	[565]	[470,311,NaN]	3	hSpCas9	negative selection	9603549
97941814	97941837	8	-	27869803	HPAFII	viability after 27 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	0.37466946210758745	[519]	[480,248,NaN]	3	hSpCas9	negative selection	9603550
97961481	97961504	8	-	27869803	HPAFII	viability after 27 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.17876647969953124	[283]	[138,125,NaN]	-1	hSpCas9	negative selection	9603551
98003687	98003710	8	-	27869803	HPAFII	viability after 27 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.18137470883534185	[336]	[165,229,NaN]	1	hSpCas9	negative selection	9603552
98007187	98007210	8	+	27869803	HPAFII	viability after 27 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.2016223728690847	[454]	[339,220,NaN]	1	hSpCas9	negative selection	9603553
97888145	97888168	8	+	27869803	HPAFII	viability after 15 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	1.3342151019642166	[11]	[42,25,NaN]	9	hSpCas9	negative selection	9685997
97930963	97930986	8	+	27869803	HPAFII	viability after 15 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	0.2907318288442149	[565]	[1155,487,NaN]	3	hSpCas9	negative selection	9685998
97941814	97941837	8	-	27869803	HPAFII	viability after 15 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.13875667894840216	[519]	[818,313,NaN]	-2	hSpCas9	negative selection	9685999
97961481	97961504	8	-	27869803	HPAFII	viability after 15 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.011119570581788113	[283]	[440,216,NaN]	0	hSpCas9	negative selection	9686000
98003687	98003710	8	-	27869803	HPAFII	viability after 15 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.25218276269983414	[336]	[402,448,NaN]	3	hSpCas9	negative selection	9686001
98007187	98007210	8	+	27869803	HPAFII	viability after 15 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.2877235797231741	[454]	[747,502,NaN]	3	hSpCas9	negative selection	9686002
97888145	97888168	8	+	27869803	ASPC1	viability after 36 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	0.965787054344541	[41]	[13,75,0]	8	hSpCas9	negative selection	9768446
97930963	97930986	8	+	27869803	ASPC1	viability after 36 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	0.5422451790071205	[1306]	[495,1110,420]	5	hSpCas9	negative selection	9768447
97941814	97941837	8	-	27869803	ASPC1	viability after 36 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.5456870913974817	[1518]	[189,594,296]	-5	hSpCas9	negative selection	9768448
97961481	97961504	8	-	27869803	ASPC1	viability after 36 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.09734937346972106	[520]	[111,87,273]	-1	hSpCas9	negative selection	9768449
98003687	98003710	8	-	27869803	ASPC1	viability after 36 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.7228060350151962	[842]	[838,551,179]	7	hSpCas9	negative selection	9768450
98007187	98007210	8	+	27869803	ASPC1	viability after 36 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.012199549612192717	[1356]	[690,536,275]	0	hSpCas9	negative selection	9768451
97888145	97888168	8	+	27869803	PATU8988S	viability after 35 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	-0.869134696925943	[83]	[27,8,NaN]	-7	hSpCas9	negative selection	9850895
97930963	97930986	8	+	27869803	PATU8988S	viability after 35 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	0.39783855207415886	[1027]	[542,547,NaN]	4	hSpCas9	negative selection	9850896
97941814	97941837	8	-	27869803	PATU8988S	viability after 35 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.21536647803422815	[1262]	[277,598,NaN]	-2	hSpCas9	negative selection	9850897
97961481	97961504	8	-	27869803	PATU8988S	viability after 35 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.6254656986391571	[405]	[102,108,NaN]	-6	hSpCas9	negative selection	9850898
98003687	98003710	8	-	27869803	PATU8988S	viability after 35 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.1317221114197108	[848]	[428,319,NaN]	1	hSpCas9	negative selection	9850899
98007187	98007210	8	+	27869803	PATU8988S	viability after 35 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.08660371383336929	[1361]	[793,369,NaN]	1	hSpCas9	negative selection	9850900
97888145	97888168	8	+	27869803	PATU8988S	viability after 31 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	-0.8362902100717782	[83]	[16,20,NaN]	-7	hSpCas9	negative selection	9933344
97930963	97930986	8	+	27869803	PATU8988S	viability after 31 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	0.31768277777183485	[1027]	[509,511,NaN]	4	hSpCas9	negative selection	9933345
97941814	97941837	8	-	27869803	PATU8988S	viability after 31 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	-0.379187587113918	[1262]	[256,552,NaN]	-4	hSpCas9	negative selection	9933346
97961481	97961504	8	-	27869803	PATU8988S	viability after 31 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.8920198607754612	[405]	[66,112,NaN]	-7	hSpCas9	negative selection	9933347
98003687	98003710	8	-	27869803	PATU8988S	viability after 31 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	-0.020301647038251214	[848]	[346,316,NaN]	0	hSpCas9	negative selection	9933348
98007187	98007210	8	+	27869803	PATU8988S	viability after 31 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	-0.34855365856340914	[1361]	[455,388,NaN]	-4	hSpCas9	negative selection	9933349
97888145	97888168	8	+	27869803	HPAFII	viability after 35 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	2.340243119366512	[11]	[26,34,NaN]	9	hSpCas9	negative selection	10015793
97930963	97930986	8	+	27869803	HPAFII	viability after 35 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	0.6156113512552113	[565]	[383,500,NaN]	4	hSpCas9	negative selection	10015794
97941814	97941837	8	-	27869803	HPAFII	viability after 35 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	0.5668609627970884	[519]	[523,238,NaN]	3	hSpCas9	negative selection	10015795
97961481	97961504	8	-	27869803	HPAFII	viability after 35 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	0.2158749867631655	[283]	[126,211,NaN]	1	hSpCas9	negative selection	10015796
98003687	98003710	8	-	27869803	HPAFII	viability after 35 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.3154738783952676	[336]	[113,322,NaN]	2	hSpCas9	negative selection	10015797
98007187	98007210	8	+	27869803	HPAFII	viability after 35 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.6094465419751225	[454]	[381,316,NaN]	4	hSpCas9	negative selection	10015798
97888145	97888168	8	+	27869803	HPAFII	viability after 31 days	GATCGTCCTCCTCCCTGCCGAGG	MATN2	ENSG00000132561	1.8719244404446505	[11]	[27,20,NaN]	9	hSpCas9	negative selection	10098242
97930963	97930986	8	+	27869803	HPAFII	viability after 31 days	TGAGAACAAGCGGGCAGACCTGG	MATN2	ENSG00000132561	0.3138216391796791	[565]	[446,337,NaN]	2	hSpCas9	negative selection	10098243
97941814	97941837	8	-	27869803	HPAFII	viability after 31 days	CAGGGATGTTGATGCAGAAGTGG	MATN2	ENSG00000132561	0.6171386792097875	[519]	[561,322,NaN]	4	hSpCas9	negative selection	10098244
97961481	97961504	8	-	27869803	HPAFII	viability after 31 days	GGGCGTAGCCACTGTAGCACTGG	MATN2	ENSG00000132561	-0.015141047139106134	[283]	[117,200,NaN]	0	hSpCas9	negative selection	10098245
98003687	98003710	8	-	27869803	HPAFII	viability after 31 days	ACGCACTCATGCTCACAGCCCGG	MATN2	ENSG00000132561	0.3840485089656996	[336]	[130,372,NaN]	2	hSpCas9	negative selection	10098246
98007187	98007210	8	+	27869803	HPAFII	viability after 31 days	AGAAGGCTTCCTCATCAACGAGG	MATN2	ENSG00000132561	0.44946146565340817	[454]	[352,343,NaN]	3	hSpCas9	negative selection	10098247
98007142	98007165	8	+	28162770	P31FUJ	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	1.039657214208684	[177]	[429]	9	hSpCas9	negative selection	10189638
97888192	97888215	8	-	28162770	P31FUJ	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.2729303171196884	[801]	[779]	-3	hSpCas9	negative selection	10189639
97931294	97931317	8	-	28162770	P31FUJ	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.3274041972212063	[528]	[779]	3	hSpCas9	negative selection	10189640
98003740	98003763	8	-	28162770	P31FUJ	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	0.8016861719709121	[61]	[126]	8	hSpCas9	negative selection	10189641
98007565	98007588	8	+	28162770	P31FUJ	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	-0.4492631483431816	[444]	[382]	-4	hSpCas9	negative selection	10189642
98018076	98018099	8	+	28162770	P31FUJ	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	0.5261896960818265	[168]	[285]	6	hSpCas9	negative selection	10189643
98007142	98007165	8	+	28162770	TF1	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	NaN	[NaN]	[301]	1	hSpCas9	negative selection	10359004
97888192	97888215	8	-	28162770	TF1	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	NaN	[NaN]	[707]	1	hSpCas9	negative selection	10359005
97931294	97931317	8	-	28162770	TF1	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10359006
98003740	98003763	8	-	28162770	TF1	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10359007
98007565	98007588	8	+	28162770	TF1	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	NaN	[NaN]	[340]	1	hSpCas9	negative selection	10359008
98018076	98018099	8	+	28162770	TF1	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	NaN	[NaN]	[238]	1	hSpCas9	negative selection	10359009
98007142	98007165	8	+	28162770	SKM1	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.6509341849650393	[57]	[160]	6	hSpCas9	negative selection	10528370
97888192	97888215	8	-	28162770	SKM1	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.023998090928929683	[198]	[345]	0	hSpCas9	negative selection	10528371
97931294	97931317	8	-	28162770	SKM1	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.354396147939008	[127]	[176]	-3	hSpCas9	negative selection	10528372
98003740	98003763	8	-	28162770	SKM1	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	-0.5740741845784201	[15]	[18]	-4	hSpCas9	negative selection	10528373
98007565	98007588	8	+	28162770	SKM1	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	-0.46933007970353535	[129]	[165]	-4	hSpCas9	negative selection	10528374
98018076	98018099	8	+	28162770	SKM1	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	-1.2537179384474797	[57]	[42]	-7	hSpCas9	negative selection	10528375
98007142	98007165	8	+	28162770	SKM1	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.6509341849650393	[57]	[160]	6	hSpCas9	negative selection	10697736
97888192	97888215	8	-	28162770	SKM1	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.023998090928929683	[198]	[345]	0	hSpCas9	negative selection	10697737
97931294	97931317	8	-	28162770	SKM1	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.354396147939008	[127]	[176]	-3	hSpCas9	negative selection	10697738
98003740	98003763	8	-	28162770	SKM1	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	-0.5740741845784201	[15]	[18]	-4	hSpCas9	negative selection	10697739
98007565	98007588	8	+	28162770	SKM1	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	-0.46933007970353535	[129]	[165]	-4	hSpCas9	negative selection	10697740
98018076	98018099	8	+	28162770	SKM1	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	-1.2537179384474797	[57]	[42]	-7	hSpCas9	negative selection	10697741
98007142	98007165	8	+	28162770	PL21	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.9998409640034891	[215]	[187]	8	hSpCas9	negative selection	10867102
97888192	97888215	8	-	28162770	PL21	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	0.7128530448238573	[620]	[442]	6	hSpCas9	negative selection	10867103
97931294	97931317	8	-	28162770	PL21	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.5800791776307699	[552]	[160]	-4	hSpCas9	negative selection	10867104
98003740	98003763	8	-	28162770	PL21	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	-0.22870368431455423	[69]	[25]	-2	hSpCas9	negative selection	10867105
98007565	98007588	8	+	28162770	PL21	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	-0.18859939792019054	[452]	[172]	-1	hSpCas9	negative selection	10867106
98018076	98018099	8	+	28162770	PL21	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	-1.5038755578755991	[201]	[30]	-7	hSpCas9	negative selection	10867107
98007142	98007165	8	+	28162770	P31FUJ	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	1.039657214208684	[177]	[429]	9	hSpCas9	negative selection	11036468
97888192	97888215	8	-	28162770	P31FUJ	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.2729303171196884	[801]	[779]	-3	hSpCas9	negative selection	11036469
97931294	97931317	8	-	28162770	P31FUJ	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.3274041972212063	[528]	[779]	3	hSpCas9	negative selection	11036470
98003740	98003763	8	-	28162770	P31FUJ	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	0.8016861719709121	[61]	[126]	8	hSpCas9	negative selection	11036471
98007565	98007588	8	+	28162770	P31FUJ	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	-0.4492631483431816	[444]	[382]	-4	hSpCas9	negative selection	11036472
98018076	98018099	8	+	28162770	P31FUJ	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	0.5261896960818265	[168]	[285]	6	hSpCas9	negative selection	11036473
98007142	98007165	8	+	28162770	OCIAML5	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.04101822521949111	[83]	[155]	0	hSpCas9	negative selection	11205834
97888192	97888215	8	-	28162770	OCIAML5	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	0.3380554640553739	[464]	[1060]	3	hSpCas9	negative selection	11205835
97931294	97931317	8	-	28162770	OCIAML5	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.7489730778998933	[242]	[260]	-5	hSpCas9	negative selection	11205836
98003740	98003763	8	-	28162770	OCIAML5	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	0.5015703837507037	[26]	[68]	4	hSpCas9	negative selection	11205837
98007565	98007588	8	+	28162770	OCIAML5	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	-0.5058909297299574	[235]	[299]	-3	hSpCas9	negative selection	11205838
98018076	98018099	8	+	28162770	OCIAML5	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	0.28676113383331964	[98]	[217]	2	hSpCas9	negative selection	11205839
98007142	98007165	8	+	28162770	EOL1	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	-0.4244195760691799	[376]	[147]	-3	hSpCas9	negative selection	11375200
97888192	97888215	8	-	28162770	EOL1	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.7563101563729404	[932]	[290]	-5	hSpCas9	negative selection	11375201
97931294	97931317	8	-	28162770	EOL1	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.4651170748960727	[882]	[336]	-3	hSpCas9	negative selection	11375202
98003740	98003763	8	-	28162770	EOL1	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	0.4908945941243439	[103]	[76]	4	hSpCas9	negative selection	11375203
98007565	98007588	8	+	28162770	EOL1	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	-0.39073194730746197	[865]	[347]	-3	hSpCas9	negative selection	11375204
98018076	98018099	8	+	28162770	EOL1	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	-0.2621948479320518	[452]	[198]	-2	hSpCas9	negative selection	11375205
98007142	98007165	8	+	28162770	MOLM13	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.5850729209149179	[259]	[281]	4	hSpCas9	negative selection	11544566
97888192	97888215	8	-	28162770	MOLM13	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.9897345748578663	[996]	[362]	-5	hSpCas9	negative selection	11544567
97931294	97931317	8	-	28162770	MOLM13	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.21455825010605767	[651]	[546]	1	hSpCas9	negative selection	11544568
98003740	98003763	8	-	28162770	MOLM13	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	0.3035025636436963	[64]	[57]	2	hSpCas9	negative selection	11544569
98007565	98007588	8	+	28162770	MOLM13	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	-0.12982502658542505	[624]	[412]	-1	hSpCas9	negative selection	11544570
98018076	98018099	8	+	28162770	MOLM13	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	-1.4318057126597359	[249]	[66]	-6	hSpCas9	negative selection	11544571
98007142	98007165	8	+	28162770	HEL	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.8537937094025241	[291]	[337]	7	hSpCas9	negative selection	11713932
97888192	97888215	8	-	28162770	HEL	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.0373243709313722	[869]	[542]	0	hSpCas9	negative selection	11713933
97931294	97931317	8	-	28162770	HEL	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	0.4731471319435836	[540]	[480]	4	hSpCas9	negative selection	11713934
98003740	98003763	8	-	28162770	HEL	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	1.0733731863302194	[91]	[123]	8	hSpCas9	negative selection	11713935
98007565	98007588	8	+	28162770	HEL	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	0.6329578112077716	[591]	[587]	5	hSpCas9	negative selection	11713936
98018076	98018099	8	+	28162770	HEL	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	-0.23804800967226258	[266]	[144]	-2	hSpCas9	negative selection	11713937
98007142	98007165	8	+	28162770	MV411	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	-0.7025217667176292	[169]	[87]	-5	hSpCas9	negative selection	11883298
97888192	97888215	8	-	28162770	MV411	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.40220831954215597	[592]	[377]	-3	hSpCas9	negative selection	11883299
97931294	97931317	8	-	28162770	MV411	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.3789448773183617	[476]	[308]	-3	hSpCas9	negative selection	11883300
98003740	98003763	8	-	28162770	MV411	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	-0.1675999484960684	[35]	[26]	-1	hSpCas9	negative selection	11883301
98007565	98007588	8	+	28162770	MV411	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	0.23438139795732904	[443]	[439]	2	hSpCas9	negative selection	11883302
98018076	98018099	8	+	28162770	MV411	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	-0.223192274459386	[193]	[139]	-2	hSpCas9	negative selection	11883303
98007142	98007165	8	+	28162770	MONOMAC1	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.08424926333046273	[143]	[174]	0	hSpCas9	negative selection	12052664
97888192	97888215	8	-	28162770	MONOMAC1	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.02315481896254168	[444]	[501]	0	hSpCas9	negative selection	12052665
97931294	97931317	8	-	28162770	MONOMAC1	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.4564913626175463	[321]	[268]	-4	hSpCas9	negative selection	12052666
98003740	98003763	8	-	28162770	MONOMAC1	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	1.3879256536616025	[30]	[92]	9	hSpCas9	negative selection	12052667
98007565	98007588	8	+	28162770	MONOMAC1	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	0.0777200437987815	[285]	[345]	0	hSpCas9	negative selection	12052668
98018076	98018099	8	+	28162770	MONOMAC1	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	0.5359433991554734	[144]	[240]	5	hSpCas9	negative selection	12052669
98007142	98007165	8	+	28162770	OCIAML2	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	-0.7246754478487003	[47]	[160]	-5	hSpCas9	negative selection	12222030
97888192	97888215	8	-	28162770	OCIAML2	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.6435925373228575	[103]	[368]	-5	hSpCas9	negative selection	12222031
97931294	97931317	8	-	28162770	OCIAML2	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.4663928323556904	[84]	[340]	-4	hSpCas9	negative selection	12222032
98003740	98003763	8	-	28162770	OCIAML2	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	-0.5037966891773606	[10]	[42]	-4	hSpCas9	negative selection	12222033
98007565	98007588	8	+	28162770	OCIAML2	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	-0.1889315751433316	[79]	[388]	-1	hSpCas9	negative selection	12222034
98018076	98018099	8	+	28162770	OCIAML2	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	0.2563516803514228	[28]	[191]	2	hSpCas9	negative selection	12222035
98007142	98007165	8	+	28162770	OCIAML3	viability	GCAGCTGTGTCTGAACACGGAGG	MATN2	ENSG00000132561	0.4915680913819108	[44]	[190]	4	hSpCas9	negative selection	12391396
97888192	97888215	8	-	28162770	OCIAML3	viability	AGCGTGTCTGCCCCTAGAGATGG	MATN2	ENSG00000132561	-0.9389190532123649	[173]	[273]	-6	hSpCas9	negative selection	12391397
97931294	97931317	8	-	28162770	OCIAML3	viability	GTCACGATCATTATGACCCGTGG	MATN2	ENSG00000132561	-0.1408350121585482	[125]	[344]	-1	hSpCas9	negative selection	12391398
98003740	98003763	8	-	28162770	OCIAML3	viability	GGTCCAGAGTGTAGCCACGGTGG	MATN2	ENSG00000132561	-0.12834406797535158	[20]	[57]	-1	hSpCas9	negative selection	12391399
98007565	98007588	8	+	28162770	OCIAML3	viability	GGACACGTGCTCCGCAGCGATGG	MATN2	ENSG00000132561	0.8492267507853326	[113]	[619]	7	hSpCas9	negative selection	12391400
98018076	98018099	8	+	28162770	OCIAML3	viability	GGAGGGATTCCGGCTCGCTGAGG	MATN2	ENSG00000132561	-0.5442546051270635	[56]	[117]	-4	hSpCas9	negative selection	12391401