Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4157
• Symbol:MC1R
• Description:melanocortin 1 receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/MC1R

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
89917678	89917701	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACATGGAGGTGGCTTGTGAGTGG	MC1R	ENSG00000258839	0.4290010375941403	[49,25]	[5,16]	2	dCas9-VP64	positive selection	2430406
89917705	89917728	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCATTTCATGGTCAGAGTTTGG	MC1R	ENSG00000258839	0.9838583602047638	[92,174]	[7,112]	4	dCas9-VP64	positive selection	2430407
89917728	89917751	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGTTGGGCGAGAGACAGGATGG	MC1R	ENSG00000258839	-0.17243874796398506	[1,39]	[2,3]	0	dCas9-VP64	positive selection	2430408
89917678	89917701	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACATGGAGGTGGCTTGTGAGTGG	MC1R	ENSG00000258839	0.4240397481960183	[34,128]	[14,53]	3	dCas9-VP64	positive selection	2525661
89917705	89917728	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCATTTCATGGTCAGAGTTTGG	MC1R	ENSG00000258839	0.6630553096670282	[151,145]	[38,112]	5	dCas9-VP64	positive selection	2525662
89917728	89917751	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGTTGGGCGAGAGACAGGATGG	MC1R	ENSG00000258839	2.752411074946612	[18,134]	[3,320]	9	dCas9-VP64	positive selection	2525663
89918178	89918201	16	+	27661255	K562	viability	GGTCCCTGAAGACCTCACTAGGG	MC1R	ENSG00000258839	0.049390869789004754	[341,528]	[421,301]	1	dCas9-KRAB	negative selection	5492571
89918280	89918303	16	+	27661255	K562	viability	GGGCGAGGCTGGGCCCTTGGGGG	MC1R	ENSG00000258839	-0.29189362958989684	[385,489]	[303,267]	-7	dCas9-KRAB	negative selection	5492572