Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4160
• Symbol:MC4R
• Description:melanocortin 4 receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/MC4R

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
60372313	60372336	18	+	26472758	Jiyoye	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	0.8844971590390598	[152]	[212]	6	hSpCas9	negative selection	97394
60372249	60372272	18	-	26472758	Jiyoye	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	-0.0509308396648564	[135]	[98]	0	hSpCas9	negative selection	97395
60371644	60371667	18	+	26472758	Jiyoye	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	3.1389792705563004	[13]	[92]	9	hSpCas9	negative selection	97396
60372327	60372350	18	-	26472758	Jiyoye	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	1.374008517570674	[43]	[85]	8	hSpCas9	negative selection	97397
60371367	60371390	18	+	26472758	Jiyoye	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.4964427196029608	[46]	[49]	4	hSpCas9	negative selection	97398
60372277	60372300	18	+	26472758	Jiyoye	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.9646571458049227	[317]	[467]	6	hSpCas9	negative selection	97399
60372234	60372257	18	-	26472758	Jiyoye	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.30861154702228377	[211]	[197]	2	hSpCas9	negative selection	97400
60371914	60371937	18	-	26472758	Jiyoye	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.3410230465009463	[356]	[340]	2	hSpCas9	negative selection	97401
60371591	60371614	18	+	26472758	Jiyoye	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	1.9921378822270297	[22]	[68]	8	hSpCas9	negative selection	97402
60371689	60371712	18	+	26472758	Jiyoye	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	-6.413003580909314	[112]	[0]	-9	hSpCas9	negative selection	97403
60372313	60372336	18	+	26472758	KBM7	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-0.5332227134502893	[993,520]	[296,187]	-5	hSpCas9	negative selection	288512
60372249	60372272	18	-	26472758	KBM7	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	0.668996853810186	[531,616]	[541,338]	7	hSpCas9	negative selection	288513
60371644	60371667	18	+	26472758	KBM7	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	0.15237762160560708	[356,177]	[169,104]	1	hSpCas9	negative selection	288514
60372327	60372350	18	-	26472758	KBM7	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.6990061042767239	[318,188]	[203,176]	7	hSpCas9	negative selection	288515
60371367	60371390	18	+	26472758	KBM7	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.17816651014190144	[365,168]	[134,139]	1	hSpCas9	negative selection	288516
60372277	60372300	18	+	26472758	KBM7	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.518692700969348	[1980,1891]	[1746,914]	5	hSpCas9	negative selection	288517
60372234	60372257	18	-	26472758	KBM7	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.9054434653156491	[784,890]	[549,921]	8	hSpCas9	negative selection	288518
60371914	60371937	18	-	26472758	KBM7	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.471207030991865	[1528,1086]	[681,984]	5	hSpCas9	negative selection	288519
60371591	60371614	18	+	26472758	KBM7	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	0.7736977592723282	[248,273]	[112,300]	8	hSpCas9	negative selection	288520
60371689	60371712	18	+	26472758	KBM7	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	-0.11886829314126102	[256,281]	[92,139]	-1	hSpCas9	negative selection	288521
60372313	60372336	18	+	26472758	Raji	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-0.3470589311760225	[432]	[78]	-3	hSpCas9	negative selection	479630
60372249	60372272	18	-	26472758	Raji	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	-0.08119417297060494	[505]	[110]	0	hSpCas9	negative selection	479631
60371644	60371667	18	+	26472758	Raji	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-0.11832924425445979	[144]	[30]	-1	hSpCas9	negative selection	479632
60372327	60372350	18	-	26472758	Raji	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.0827214811393302	[117]	[28]	0	hSpCas9	negative selection	479633
60371367	60371390	18	+	26472758	Raji	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	1.3244816570405344	[116]	[67]	9	hSpCas9	negative selection	479634
60372277	60372300	18	+	26472758	Raji	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.3698817230109621	[896]	[268]	3	hSpCas9	negative selection	479635
60372234	60372257	18	-	26472758	Raji	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.16121295210326947	[604]	[156]	1	hSpCas9	negative selection	479636
60371914	60371937	18	-	26472758	Raji	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.8619892886755358	[568]	[239]	7	hSpCas9	negative selection	479637
60371591	60371614	18	+	26472758	Raji	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	0.4604932855092416	[118]	[37]	4	hSpCas9	negative selection	479638
60371689	60371712	18	+	26472758	Raji	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	-0.6295820587926069	[99]	[14]	-5	hSpCas9	negative selection	479639
60372313	60372336	18	+	26472758	K562	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-2.851299901726093	[700]	[81]	-8	hSpCas9	negative selection	670748
60372249	60372272	18	-	26472758	K562	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	1.173119401574271	[673]	[1282]	8	hSpCas9	negative selection	670749
60371644	60371667	18	+	26472758	K562	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-0.8201903537566296	[273]	[130]	-5	hSpCas9	negative selection	670750
60372327	60372350	18	-	26472758	K562	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.5425982197812005	[195]	[240]	4	hSpCas9	negative selection	670751
60371367	60371390	18	+	26472758	K562	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.7898528642009655	[147]	[215]	6	hSpCas9	negative selection	670752
60372277	60372300	18	+	26472758	K562	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	1.1586701834145328	[1576]	[2971]	8	hSpCas9	negative selection	670753
60372234	60372257	18	-	26472758	K562	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.49582513124740135	[871]	[1037]	4	hSpCas9	negative selection	670754
60371914	60371937	18	-	26472758	K562	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	1.1253901440978331	[965]	[1778]	8	hSpCas9	negative selection	670755
60371591	60371614	18	+	26472758	K562	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	0.4802758724301416	[258]	[304]	4	hSpCas9	negative selection	670756
60371689	60371712	18	+	26472758	K562	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	1.0744937262241345	[125]	[223]	8	hSpCas9	negative selection	670757
60371367	60371390	18	+	26627737	DLD1	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.3223154666999448	[222]	[112,75,73]	3	hSpCas9	negative selection	801831
60371911	60371934	18	+	26627737	DLD1	viability	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	-0.2571808752179152	[669]	[144,147,223]	-3	hSpCas9	negative selection	801832
60372286	60372309	18	+	26627737	DLD1	viability	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.05770250990754425	[401]	[185,143,71]	0	hSpCas9	negative selection	801833
60371367	60371390	18	+	26627737	GBM cells	viability after 5 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.7664220422994907	[202]	[51,75]	-8	hSpCas9	negative selection	884146
60371911	60371934	18	+	26627737	GBM cells	viability after 5 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.31093002218929244	[477]	[316,318]	5	hSpCas9	negative selection	884147
60372286	60372309	18	+	26627737	GBM cells	viability after 5 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.23098992514913078	[254]	[146,173]	3	hSpCas9	negative selection	884148
60371367	60371390	18	+	26627737	GBM cells	viability after 13 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.6290103472554438	[202]	[100,46]	-6	hSpCas9	negative selection	966461
60371911	60371934	18	+	26627737	GBM cells	viability after 13 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.17704273183947727	[477]	[306,281]	2	hSpCas9	negative selection	966462
60372286	60372309	18	+	26627737	GBM cells	viability after 13 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.4224530873423806	[254]	[212,162]	5	hSpCas9	negative selection	966463
60371367	60371390	18	+	26627737	GBM cells	viability after 21 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.7656972183969248	[202]	[67,61]	-6	hSpCas9	negative selection	1048776
60371911	60371934	18	+	26627737	GBM cells	viability after 21 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.130467618785567	[477]	[277,289]	1	hSpCas9	negative selection	1048777
60372286	60372309	18	+	26627737	GBM cells	viability after 21 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.8453022828504737	[254]	[262,235]	8	hSpCas9	negative selection	1048778
60371367	60371390	18	+	26627737	RPE1	viability after 9 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.9057297602885834	[744]	[120,128]	-6	hSpCas9	negative selection	1131091
60371911	60371934	18	+	26627737	RPE1	viability after 9 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	1.9914139536774549	[426]	[555,499]	8	hSpCas9	negative selection	1131092
60372286	60372309	18	+	26627737	RPE1	viability after 9 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	-0.7175868442942541	[730]	[191,70]	-5	hSpCas9	negative selection	1131093
60371367	60371390	18	+	26627737	RPE1	viability after 12 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.12725958217970573	[744]	[157,209]	-1	hSpCas9	negative selection	1213406
60371911	60371934	18	+	26627737	RPE1	viability after 12 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	2.264974609175476	[426]	[649,446]	9	hSpCas9	negative selection	1213407
60372286	60372309	18	+	26627737	RPE1	viability after 12 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	-0.02751038028218361	[730]	[215,167]	0	hSpCas9	negative selection	1213408
60371367	60371390	18	+	26627737	RPE1	viability after 15 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.17540613399950045	[744]	[179,192]	-1	hSpCas9	negative selection	1295721
60371911	60371934	18	+	26627737	RPE1	viability after 15 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	2.621103433891315	[426]	[848,640]	9	hSpCas9	negative selection	1295722
60372286	60372309	18	+	26627737	RPE1	viability after 15 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	-0.27471805076150024	[730]	[202,139]	-2	hSpCas9	negative selection	1295723
60371367	60371390	18	+	26627737	RPE1	viability after 18 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.07109594148796629	[744]	[260,157]	0	hSpCas9	negative selection	1378036
60371911	60371934	18	+	26627737	RPE1	viability after 18 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	2.008923216456741	[426]	[486,438]	8	hSpCas9	negative selection	1378037
60372286	60372309	18	+	26627737	RPE1	viability after 18 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	-0.14089306842203705	[730]	[263,87]	-1	hSpCas9	negative selection	1378038
60371367	60371390	18	+	26627737	HeLa	viability after 8 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.3485339823988074	[204]	[104,166,69]	3	hSpCas9	negative selection	1460351
60371911	60371934	18	+	26627737	HeLa	viability after 8 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.6612308233350073	[574]	[594,300,338]	5	hSpCas9	negative selection	1460352
60372286	60372309	18	+	26627737	HeLa	viability after 8 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.49142648778746995	[261]	[386,120,31]	4	hSpCas9	negative selection	1460353
60371367	60371390	18	+	26627737	HeLa	viability after 12 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.4500771584453337	[204]	[38,74,69]	-4	hSpCas9	negative selection	1542666
60371911	60371934	18	+	26627737	HeLa	viability after 12 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.7811720926662298	[574]	[749,219,284]	6	hSpCas9	negative selection	1542667
60372286	60372309	18	+	26627737	HeLa	viability after 12 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.22637037291012874	[261]	[188,124,67]	2	hSpCas9	negative selection	1542668
60371367	60371390	18	+	26627737	HeLa	viability after 15 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-1.653491734633627	[204]	[13,11,55]	-8	hSpCas9	negative selection	1624981
60371911	60371934	18	+	26627737	HeLa	viability after 15 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.5047495829515238	[574]	[333,346,313]	4	hSpCas9	negative selection	1624982
60372286	60372309	18	+	26627737	HeLa	viability after 15 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.815410099476952	[261]	[276,144,135]	6	hSpCas9	negative selection	1624983
60371367	60371390	18	+	26627737	HeLa	viability after 18 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-1.60788184380118	[204]	[10,9,55]	-8	hSpCas9	negative selection	1707296
60371911	60371934	18	+	26627737	HeLa	viability after 18 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.5492468014196499	[574]	[234,298,313]	4	hSpCas9	negative selection	1707297
60372286	60372309	18	+	26627737	HeLa	viability after 18 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.8054617139134734	[261]	[180,122,135]	6	hSpCas9	negative selection	1707298
60371367	60371390	18	+	26627737	HCT116	viability after 6 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	1.2293769885497454	[322]	[178,85]	6	hSpCas9	negative selection	1789611
60371911	60371934	18	+	26627737	HCT116	viability after 6 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.10489503601410144	[939]	[107,186]	0	hSpCas9	negative selection	1789612
60372286	60372309	18	+	26627737	HCT116	viability after 6 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.101011977580999	[823]	[136,139]	0	hSpCas9	negative selection	1789613
60371367	60371390	18	+	26627737	HCT116	viability after 8 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.22562110118246415	[180]	[128,97,122]	2	hSpCas9	negative selection	1871926
60371911	60371934	18	+	26627737	HCT116	viability after 8 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	-0.14071756255893397	[517]	[236,335,203]	-1	hSpCas9	negative selection	1871927
60372286	60372309	18	+	26627737	HCT116	viability after 8 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.5029555215823371	[260]	[163,266,179]	5	hSpCas9	negative selection	1871928
60371367	60371390	18	+	26627737	HCT116	viability after 9 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.859078380578892	[322]	[94,204]	6	hSpCas9	negative selection	1954241
60371911	60371934	18	+	26627737	HCT116	viability after 9 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	-0.2255727578180704	[939]	[255,181]	-1	hSpCas9	negative selection	1954242
60372286	60372309	18	+	26627737	HCT116	viability after 9 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	-0.5305935138517872	[823]	[196,116]	-4	hSpCas9	negative selection	1954243
60371367	60371390	18	+	26627737	HCT116	viability after 12 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.18673511972578727	[180]	[70,90,89]	-2	hSpCas9	negative selection	2036556
60371911	60371934	18	+	26627737	HCT116	viability after 12 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	-0.7126397661099129	[517]	[78,207,219]	-6	hSpCas9	negative selection	2036557
60372286	60372309	18	+	26627737	HCT116	viability after 12 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.6515989834982303	[260]	[239,204,198]	6	hSpCas9	negative selection	2036558
60371367	60371390	18	+	26627737	HCT116	viability after 15 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.6697015446839468	[180]	[155,96,240]	6	hSpCas9	negative selection	2118871
60371911	60371934	18	+	26627737	HCT116	viability after 15 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	-0.3097980391281958	[517]	[207,259,247]	-3	hSpCas9	negative selection	2118872
60372286	60372309	18	+	26627737	HCT116	viability after 15 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.45479367699756634	[260]	[201,216,196]	4	hSpCas9	negative selection	2118873
60371367	60371390	18	+	26627737	HCT116	viability after 18 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.3537515636584106	[180]	[101,76,160]	3	hSpCas9	negative selection	2201186
60371911	60371934	18	+	26627737	HCT116	viability after 18 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	-0.891680400480521	[517]	[94,107,206]	-7	hSpCas9	negative selection	2201187
60372286	60372309	18	+	26627737	HCT116	viability after 18 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.7572549645628198	[260]	[141,146,361]	6	hSpCas9	negative selection	2201188
60371855	60371878	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAACATTATGACAGTTAAGCGG	MC4R	ENSG00000166603	0.1434402070127376	[3,3]	[2,4]	3	hSpCas9	positive selection	3001561
60372278	60372301	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.1735789331354639	[3,3]	[3,3]	3	hSpCas9	positive selection	3001562
60371855	60371878	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAACATTATGACAGTTAAGCGG	MC4R	ENSG00000166603	0.39528653369956623	[3,3]	[4,3]	7	hSpCas9	positive selection	3069419
60372278	60372301	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	-0.8188843856070042	[3,3]	[2,0]	-9	hSpCas9	positive selection	3069420
60371623	60371646		-	24336571	A375	resistance to PLX after 7 days	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	0.42090445143391425	[9,8]	[12,12]	9	hSpCas9	positive selection	3126708
60371612	60371635		+	24336571	A375	resistance to PLX after 7 days	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	-0.5294521561911223	[13,8]	[7,7]	-9	hSpCas9	positive selection	3126709
60371623	60371646		-	24336571	A375	resistance to PLX after 14 days	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	0.8491194534047126	[7,14]	[9,8]	7	hSpCas9	positive selection	3184501
60371612	60371635		+	24336571	A375	resistance to PLX after 14 days	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.08730586336369554	[13,7]	[3,5]	1	hSpCas9	positive selection	3184502
60371623	60371646		-	24336571	A375	viability after 7 days	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	-0.08479554224768221	[10]	[9,8]	-1	hSpCas9	negative selection	3242294
60371612	60371635		+	24336571	A375	viability after 7 days	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	-0.22798354234277884	[13]	[13,8]	-3	hSpCas9	negative selection	3242295
60371623	60371646		-	24336571	A375	viability after 14 days	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	0.17680470629728992	[10]	[7,14]	2	hSpCas9	negative selection	3300087
60371612	60371635		+	24336571	A375	viability after 14 days	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	-0.28074436721259083	[13]	[13,7]	-3	hSpCas9	negative selection	3300088
60371828	60371851	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	-0.01879819382840228	[154,154]	[0,0]	0	hSpCas9	positive selection	3378719
60371383	60371406	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-1.9175994710548439	[577,577]	[0,0]	-9	hSpCas9	positive selection	3378720
60371581	60371604	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.057653866609470694	[146,146]	[0,0]	0	hSpCas9	positive selection	3378721
60371855	60371878	18	-	26780180	HT29	viability (Avana library 4 designs)	ATAACATTATGACAGTTAAGCGG	MC4R	ENSG00000166603	1.44125158339288	[]	[]	5	hSpCas9	negative selection	3439277
60371911	60371934	18	+	26780180	HT29	viability (Avana library 4 designs)	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	-0.706023911685348	[]	[]	-8	hSpCas9	negative selection	3439278
60372277	60372300	18	+	26780180	HT29	viability (Avana library 4 designs)	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.482527268986674	[]	[]	1	hSpCas9	negative selection	3439279
60372085	60372108	18	-	26780180	HT29	viability (Avana library 4 designs)	TTTCATCTGCAGCTTGGCTGTGG	MC4R	ENSG00000166603	1.48089574738364	[]	[]	6	hSpCas9	negative selection	3439280
60371911	60371934	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	1.77583861426922	[]	[]	2	hSpCas9	negative selection	3528952
60372085	60372108	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCATCTGCAGCTTGGCTGTGG	MC4R	ENSG00000166603	6.1233726931897	[]	[]	9	hSpCas9	negative selection	3528953
60371855	60371878	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAACATTATGACAGTTAAGCGG	MC4R	ENSG00000166603	-13.7736952433244	[]	[]	-8	hSpCas9	negative selection	3528954
60372277	60372300	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	3.36626198855644	[]	[]	5	hSpCas9	negative selection	3528955
60371911	60371934	18	+	26780180	A375	viability (Avana lentiGuide)	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	-6.7580833332927	[]	[]	-9	hSpCas9	negative selection	3637611
60372085	60372108	18	-	26780180	A375	viability (Avana lentiGuide)	TTTCATCTGCAGCTTGGCTGTGG	MC4R	ENSG00000166603	0.852897568076278	[]	[]	1	hSpCas9	negative selection	3637612
60371855	60371878	18	-	26780180	A375	viability (Avana lentiGuide)	ATAACATTATGACAGTTAAGCGG	MC4R	ENSG00000166603	-0.754321201328111	[]	[]	-1	hSpCas9	negative selection	3637613
60372277	60372300	18	+	26780180	A375	viability (Avana lentiGuide)	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	-3.04153759095158	[]	[]	-5	hSpCas9	negative selection	3637614
60371911	60371934	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.1049560932382047	[4]	[3,5]	2	hSpCas9	positive selection	3746270
60372085	60372108	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCATCTGCAGCTTGGCTGTGG	MC4R	ENSG00000166603	0.13952633430264666	[5]	[6,4]	4	hSpCas9	positive selection	3746271
60371855	60371878	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAACATTATGACAGTTAAGCGG	MC4R	ENSG00000166603	-0.9777939808815113	[8]	[4,3]	-8	hSpCas9	positive selection	3746272
60372277	60372300	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.26300687934385697	[5]	[6,6]	7	hSpCas9	positive selection	3746273
60371911	60371934	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.05448021027544782	[5]	[3,6]	1	hSpCas9	positive selection	3854877
60372085	60372108	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCATCTGCAGCTTGGCTGTGG	MC4R	ENSG00000166603	-0.3082827854987668	[5]	[2,4]	-4	hSpCas9	positive selection	3854878
60371855	60371878	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAACATTATGACAGTTAAGCGG	MC4R	ENSG00000166603	-0.21506089425202118	[5]	[3,3]	-3	hSpCas9	positive selection	3854879
60372277	60372300	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.3970904972265439	[4]	[6,4]	9	hSpCas9	positive selection	3854880
60371581	60371604	18	+	26780180	A375	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	1.04037410436474	[]	[]	5	hSpCas9	negative selection	3960347
60372327	60372350	18	-	26780180	A375	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	1.10606317301936	[]	[]	5	hSpCas9	negative selection	3960348
60371623	60371646	18	-	26780180	A375	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	0.340206534138015	[]	[]	0	hSpCas9	negative selection	3960349
60371383	60371406	18	-	26780180	A375	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	2.47466303708724	[]	[]	9	hSpCas9	negative selection	3960350
60371828	60371851	18	-	26780180	A375	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	1.24585157037175	[]	[]	6	hSpCas9	negative selection	3960351
60371612	60371635	18	+	26780180	A375	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	1.18052414856661	[]	[]	6	hSpCas9	negative selection	3960352
60371581	60371604	18	+	26780180	HT29	viability (GeCKOv2 library)	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	1.80988846569353	[]	[]	8	hSpCas9	negative selection	4068313
60372327	60372350	18	-	26780180	HT29	viability (GeCKOv2 library)	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	1.36868046669745	[]	[]	7	hSpCas9	negative selection	4068314
60371623	60371646	18	-	26780180	HT29	viability (GeCKOv2 library)	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	0.0489710541875937	[]	[]	0	hSpCas9	negative selection	4068315
60371383	60371406	18	-	26780180	HT29	viability (GeCKOv2 library)	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	2.98690694187976	[]	[]	9	hSpCas9	negative selection	4068316
60371828	60371851	18	-	26780180	HT29	viability (GeCKOv2 library)	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	1.63219469953903	[]	[]	8	hSpCas9	negative selection	4068317
60371612	60371635	18	+	26780180	HT29	viability (GeCKOv2 library)	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.217706464902729	[]	[]	0	hSpCas9	negative selection	4068318
60371623	60371646	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	0.5058713627594018	[2]	[2,3]	9	hSpCas9	positive selection	4151002
60371612	60371635	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.08873870791770459	[3]	[1,2]	2	hSpCas9	positive selection	4151003
60371623	60371646	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	0.02202329560365543	[2]	[0,2,0,0]	0	hSpCas9	positive selection	4215024
60371612	60371635	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	1.5804382329609543	[3]	[3,1,6,6]	9	hSpCas9	positive selection	4215025
60371612	60371635	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	-0.11037103118986216	[3]	[3,0]	-2	hSpCas9	positive selection	4282209
60371623	60371646	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	0.5022691699136677	[0]	[0,0]	9	hSpCas9	positive selection	4282210
60372327	60372350	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.4143383698025883	[2]	[2,3]	8	hSpCas9	positive selection	4282211
60371828	60371851	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	-0.48868494247864863	[2]	[2,0]	-8	hSpCas9	positive selection	4346467
60371383	60371406	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.34775866529925387	[5]	[3,2]	-6	hSpCas9	positive selection	4346468
60371581	60371604	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.08402662464220637	[2]	[1,2]	1	hSpCas9	positive selection	4346469
60371850	60371872	18	-	27760321	OCIAML3	viability	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	0.2677362653893215	[281,281]	[212,335]	3	hSpCas9	negative selection	4417203
60371909	60371931	18	-	27760321	OCIAML3	viability	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	0.28166680192380916	[539,491]	[432,564]	3	hSpCas9	negative selection	4417204
60372013	60372035	18	-	27760321	OCIAML3	viability	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	-3.087938874730188	[12,8]	[0,0]	-9	hSpCas9	negative selection	4417205
60372187	60372209	18	+	27760321	OCIAML3	viability	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	0.011863129296047464	[567,409]	[333,443]	0	hSpCas9	negative selection	4417206
60372233	60372255	18	-	27760321	OCIAML3	viability	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	-0.3630344480262287	[381,293]	[157,263]	-4	hSpCas9	negative selection	4417207
60371850	60371872	18	-	27760321	OCIAML2	viability	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	-0.787878123340204	[281,281]	[91,185]	-7	hSpCas9	negative selection	4500666
60371909	60371931	18	-	27760321	OCIAML2	viability	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	0.4438376177926813	[539,491]	[579,550]	6	hSpCas9	negative selection	4500667
60372013	60372035	18	-	27760321	OCIAML2	viability	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	-2.2390019414840516	[12,8]	[0,2]	-9	hSpCas9	negative selection	4500668
60372187	60372209	18	+	27760321	OCIAML2	viability	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	0.09314464033815542	[567,409]	[286,589]	1	hSpCas9	negative selection	4500669
60372233	60372255	18	-	27760321	OCIAML2	viability	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	0.26339299817533635	[381,293]	[317,335]	3	hSpCas9	negative selection	4500670
60371850	60371872	18	-	27760321	MV411	viability	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	1.2809492832372427	[281,281]	[557,296]	8	hSpCas9	negative selection	4584129
60371909	60371931	18	-	27760321	MV411	viability	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	1.3224874075807884	[539,491]	[787,945]	8	hSpCas9	negative selection	4584130
60372013	60372035	18	-	27760321	MV411	viability	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	0.8345759437425064	[12,8]	[5,22]	6	hSpCas9	negative selection	4584131
60372187	60372209	18	+	27760321	MV411	viability	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	0.9450489578865557	[567,409]	[210,1221]	7	hSpCas9	negative selection	4584132
60372233	60372255	18	-	27760321	MV411	viability	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	-0.1410863294009101	[381,293]	[163,255]	-1	hSpCas9	negative selection	4584133
60371850	60371872	18	-	27760321	HL60	viability	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	-0.29192432443115013	[281,281]	[197,178]	-3	hSpCas9	negative selection	4667592
60371909	60371931	18	-	27760321	HL60	viability	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	0.8729796978909972	[539,491]	[1021,505]	8	hSpCas9	negative selection	4667593
60372013	60372035	18	-	27760321	HL60	viability	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	-3.150730467609643	[12,8]	[0,0]	-9	hSpCas9	negative selection	4667594
60372187	60372209	18	+	27760321	HL60	viability	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	-0.462550656823603	[567,409]	[236,339]	-5	hSpCas9	negative selection	4667595
60372233	60372255	18	-	27760321	HL60	viability	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	-0.8469346635398278	[381,293]	[147,156]	-7	hSpCas9	negative selection	4667596
60371850	60371872	18	-	27760321	HT1080	viability	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	1.6060555937446632	[281,219]	[322,283]	8	hSpCas9	negative selection	4751055
60371909	60371931	18	-	27760321	HT1080	viability	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	0.07070346420225743	[491,383]	[177,188]	0	hSpCas9	negative selection	4751056
60372013	60372035	18	-	27760321	HT1080	viability	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	-1.671875160129228	[8,6]	[0,0]	-6	hSpCas9	negative selection	4751057
60372187	60372209	18	+	27760321	HT1080	viability	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	-0.2182747398125531	[409,319]	[50,205]	-1	hSpCas9	negative selection	4751058
60372233	60372255	18	-	27760321	HT1080	viability	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	0.7179904008941438	[293,229]	[154,189]	4	hSpCas9	negative selection	4751059
60371850	60371872	18	-	27760321	HT29	viability after 7 days	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	-0.5377174343737267	[281,219]	[227,172,264]	-7	hSpCas9	negative selection	4834518
60371909	60371931	18	-	27760321	HT29	viability after 7 days	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	0.2119363028241864	[491,383]	[738,411,811]	3	hSpCas9	negative selection	4834519
60372013	60372035	18	-	27760321	HT29	viability after 7 days	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	0.42519044901946756	[8,6]	[1,0,35]	6	hSpCas9	negative selection	4834520
60372187	60372209	18	+	27760321	HT29	viability after 7 days	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	0.46461282235209855	[409,319]	[760,612,585]	7	hSpCas9	negative selection	4834521
60372233	60372255	18	-	27760321	HT29	viability after 7 days	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	0.15771567787431695	[293,229]	[580,415,165]	2	hSpCas9	negative selection	4834522
60371850	60371872	18	-	27760321	HT29	viability after 25 days	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	-0.4593120611943785	[281,219]	[245,135,244]	-4	hSpCas9	negative selection	4917981
60371909	60371931	18	-	27760321	HT29	viability after 25 days	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	0.27471858249155556	[491,383]	[580,503,746]	3	hSpCas9	negative selection	4917982
60372013	60372035	18	-	27760321	HT29	viability after 25 days	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	0.48550273706945735	[8,6]	[30,3,0]	5	hSpCas9	negative selection	4917983
60372187	60372209	18	+	27760321	HT29	viability after 25 days	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	0.6027311397798321	[409,319]	[641,535,730]	6	hSpCas9	negative selection	4917984
60372233	60372255	18	-	27760321	HT29	viability after 25 days	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	0.6200776813943217	[293,229]	[434,431,520]	7	hSpCas9	negative selection	4917985
60371850	60371872	18	-	27760321	HT29	viability after 22 days	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	-0.33064985324547436	[281,219]	[210,220,260]	-3	hSpCas9	negative selection	5001444
60371909	60371931	18	-	27760321	HT29	viability after 22 days	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	0.4329809056112228	[491,383]	[767,642,636]	5	hSpCas9	negative selection	5001445
60372013	60372035	18	-	27760321	HT29	viability after 22 days	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	0.4654860546055284	[8,6]	[23,0,12]	5	hSpCas9	negative selection	5001446
60372187	60372209	18	+	27760321	HT29	viability after 22 days	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	0.6980899336759765	[409,319]	[739,645,665]	7	hSpCas9	negative selection	5001447
60372233	60372255	18	-	27760321	HT29	viability after 22 days	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	-0.051772925134302594	[293,229]	[246,334,295]	0	hSpCas9	negative selection	5001448
60371850	60371872	18	-	27760321	HT29	viability after 19 days	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	-1.008780586158628	[281,219]	[270,72,98]	-6	hSpCas9	negative selection	5084907
60371909	60371931	18	-	27760321	HT29	viability after 19 days	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	0.31103506026622163	[491,383]	[558,290,992]	3	hSpCas9	negative selection	5084908
60372013	60372035	18	-	27760321	HT29	viability after 19 days	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	-1.691788112906611	[8,6]	[6,0,0]	-7	hSpCas9	negative selection	5084909
60372187	60372209	18	+	27760321	HT29	viability after 19 days	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	0.6870733864151924	[409,319]	[680,348,974]	7	hSpCas9	negative selection	5084910
60372233	60372255	18	-	27760321	HT29	viability after 19 days	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	0.14432780672618462	[293,229]	[412,391,201]	1	hSpCas9	negative selection	5084911
60371850	60371872	18	-	27760321	HT29	viability after 16 days	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	-0.5296676387454519	[281,219]	[257,214,115]	-5	hSpCas9	negative selection	5168370
60371909	60371931	18	-	27760321	HT29	viability after 16 days	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	-0.14905176146916205	[491,383]	[392,522,402]	-1	hSpCas9	negative selection	5168371
60372013	60372035	18	-	27760321	HT29	viability after 16 days	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	-1.4430150952117353	[8,6]	[3,0,4]	-8	hSpCas9	negative selection	5168372
60372187	60372209	18	+	27760321	HT29	viability after 16 days	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	0.5231361367028978	[409,319]	[540,629,583]	6	hSpCas9	negative selection	5168373
60372233	60372255	18	-	27760321	HT29	viability after 16 days	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	0.29103768763019344	[293,229]	[264,250,553]	3	hSpCas9	negative selection	5168374
60371850	60371872	18	-	27760321	HT29	viability after 13 days	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	-0.34492600467603485	[281,219]	[276,272,142]	-4	hSpCas9	negative selection	5251833
60371909	60371931	18	-	27760321	HT29	viability after 13 days	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	0.5738043811970335	[491,383]	[950,554,761]	7	hSpCas9	negative selection	5251834
60372013	60372035	18	-	27760321	HT29	viability after 13 days	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	-0.9138022080435606	[8,6]	[12,0,0]	-7	hSpCas9	negative selection	5251835
60372187	60372209	18	+	27760321	HT29	viability after 13 days	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	0.3466902098555226	[409,319]	[568,452,589]	4	hSpCas9	negative selection	5251836
60372233	60372255	18	-	27760321	HT29	viability after 13 days	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	0.3304725670831463	[293,229]	[328,421,394]	4	hSpCas9	negative selection	5251837
60371850	60371872	18	-	27760321	HT29	viability after 10 days	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	-0.7228206538534522	[281,219]	[293,90,181]	-7	hSpCas9	negative selection	5335296
60371909	60371931	18	-	27760321	HT29	viability after 10 days	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	0.14588948324576667	[491,383]	[520,660,633]	2	hSpCas9	negative selection	5335297
60372013	60372035	18	-	27760321	HT29	viability after 10 days	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	-2.3185776684676114	[8,6]	[3,0,0]	-9	hSpCas9	negative selection	5335298
60372187	60372209	18	+	27760321	HT29	viability after 10 days	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	0.8937623186701363	[409,319]	[973,727,834]	9	hSpCas9	negative selection	5335299
60372233	60372255	18	-	27760321	HT29	viability after 10 days	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	0.08291265237322187	[293,229]	[420,322,295]	1	hSpCas9	negative selection	5335300
60371850	60371872	18	-	27760321	MOLM13	viability	TTATGACAGTTAAGCGGGTTGG	MC4R	ENSG00000166603	1.5874752018808929	[281,281]	[644,338]	9	hSpCas9	negative selection	5418759
60371909	60371931	18	-	27760321	MOLM13	viability	GCTTTCAATTGCAGTGGACAGG	MC4R	ENSG00000166603	1.715090576825798	[539,491]	[1152,786]	9	hSpCas9	negative selection	5418760
60372013	60372035	18	-	27760321	MOLM13	viability	CTATTAAACAGTACAGATACGG	MC4R	ENSG00000166603	-2.616803492987911	[12,8]	[0,0]	-8	hSpCas9	negative selection	5418761
60372187	60372209	18	+	27760321	MOLM13	viability	CCAGAGTCACAAACACCTCAGG	MC4R	ENSG00000166603	2.342942889044723	[567,409]	[272,2332]	9	hSpCas9	negative selection	5418762
60372233	60372255	18	-	27760321	MOLM13	viability	AAAAGGCTACTCTGATGGAGGG	MC4R	ENSG00000166603	1.0148144743612206	[381,293]	[449,324]	7	hSpCas9	negative selection	5418763
60372310	60372333	18	+	27661255	K562	viability	GCAGAGAAGTGTGCATCCCACGG	MC4R	ENSG00000166603	0.3010232179597349	[794,1103]	[1030,841]	8	dCas9-KRAB	negative selection	5492581
60372332	60372355	18	+	27661255	K562	viability	GTGGGTGGAGTTCACCATGCTGG	MC4R	ENSG00000166603	0.287669423869975	[745,945]	[876,773]	8	dCas9-KRAB	negative selection	5492582
60371612	60371635	18	+	27260156	BXPC3	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.1322194110977276	[638]	[577,696,753,939]	3	hSpCas9	negative selection	5554669
60371623	60371646	18	-	27260156	BXPC3	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	0.960357195071901	[23]	[18,43,47,92]	9	hSpCas9	negative selection	5554670
60372327	60372350	18	-	27260156	BXPC3	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.3265412471395606	[447]	[402,640,626,706]	7	hSpCas9	negative selection	5554671
60371828	60371851	18	-	27260156	BXPC3	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	-0.06596551286621155	[378]	[332,447,367,360]	-1	hSpCas9	negative selection	5618927
60371383	60371406	18	-	27260156	BXPC3	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.6471560757768775	[2552]	[1759,1435,1708,1939]	-8	hSpCas9	negative selection	5618928
60371581	60371604	18	+	27260156	BXPC3	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.2328754098454044	[289]	[281,308,415,437]	5	hSpCas9	negative selection	5618929
60371612	60371635	18	+	27260156	A673	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.17136507594503503	[638]	[947,833,808,874]	4	hSpCas9	negative selection	5675920
60371623	60371646	18	-	27260156	A673	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.4086684088071881	[23]	[82,82,86,51]	9	hSpCas9	negative selection	5675921
60372327	60372350	18	-	27260156	A673	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.36047028961513516	[447]	[807,686,569,711]	8	hSpCas9	negative selection	5675922
60371828	60371851	18	-	27260156	A673	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.03664748595773043	[378]	[515,490,439,421]	0	hSpCas9	negative selection	5740178
60371383	60371406	18	-	27260156	A673	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5976190184409886	[2552]	[2464,1825,1718,2154]	-9	hSpCas9	negative selection	5740179
60371581	60371604	18	+	27260156	A673	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.0550562453081308	[289]	[369,291,329,462]	1	hSpCas9	negative selection	5740180
60371612	60371635	18	+	27260156	A375	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.26826996271650605	[638]	[847,1236,953,631]	4	hSpCas9	negative selection	5797171
60371623	60371646	18	-	27260156	A375	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.5467028148634023	[23]	[121,51,146,10]	9	hSpCas9	negative selection	5797172
60372327	60372350	18	-	27260156	A375	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.47695598021523156	[447]	[682,927,471,840]	7	hSpCas9	negative selection	5797173
60371828	60371851	18	-	27260156	A375	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.4607034812754424	[378]	[503,892,474,601]	6	hSpCas9	negative selection	5861429
60371383	60371406	18	-	27260156	A375	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.2108448030771055	[2552]	[2773,2901,2335,2356]	-3	hSpCas9	negative selection	5861430
60371581	60371604	18	+	27260156	A375	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.6998089911950504	[289]	[535,649,426,593]	9	hSpCas9	negative selection	5861431
60371612	60371635	18	+	27260156	COLO741	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.3273067151935538	[638]	[1220,909,960]	6	hSpCas9	negative selection	5918422
60371623	60371646	18	-	27260156	COLO741	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.3633671862307999	[23]	[70,73,89]	9	hSpCas9	negative selection	5918423
60372327	60372350	18	-	27260156	COLO741	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.36299675804442766	[447]	[808,696,708]	7	hSpCas9	negative selection	5918424
60371828	60371851	18	-	27260156	COLO741	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.08668971147718385	[378]	[587,463,496]	1	hSpCas9	negative selection	5982680
60371383	60371406	18	-	27260156	COLO741	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5761760540012157	[2552]	[2615,2203,1803]	-8	hSpCas9	negative selection	5982681
60371581	60371604	18	+	27260156	COLO741	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	-0.019193928546422323	[289]	[333,428,332]	0	hSpCas9	negative selection	5982682
60371612	60371635	18	+	27260156	CAL120	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.31888915409599183	[638]	[1285,996,740]	5	hSpCas9	negative selection	6039673
60371623	60371646	18	-	27260156	CAL120	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.6530774964863735	[23]	[139,16,130]	9	hSpCas9	negative selection	6039674
60372327	60372350	18	-	27260156	CAL120	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.7657797111829567	[447]	[743,975,1089]	9	hSpCas9	negative selection	6039675
60371828	60371851	18	-	27260156	CAL120	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.3333721299786666	[378]	[373,708,664]	5	hSpCas9	negative selection	6103931
60371383	60371406	18	-	27260156	CAL120	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.49806913940416964	[2552]	[2997,1892,1973]	-6	hSpCas9	negative selection	6103932
60371581	60371604	18	+	27260156	CAL120	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	-0.05394356682290735	[289]	[520,209,337]	-1	hSpCas9	negative selection	6103933
60371612	60371635	18	+	27260156	CADOES1	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.31202740639712556	[638]	[707,866,678,695]	5	hSpCas9	negative selection	6160924
60371623	60371646	18	-	27260156	CADOES1	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.3886150334519058	[23]	[77,60,54,38]	9	hSpCas9	negative selection	6160925
60372327	60372350	18	-	27260156	CADOES1	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.2453045204103424	[447]	[452,458,609,451]	4	hSpCas9	negative selection	6160926
60371828	60371851	18	-	27260156	CADOES1	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.2840540901533539	[378]	[538,426,283,467]	5	hSpCas9	negative selection	6225182
60371383	60371406	18	-	27260156	CADOES1	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5595687016893645	[2552]	[1350,2257,1311,1521]	-7	hSpCas9	negative selection	6225183
60371581	60371604	18	+	27260156	CADOES1	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.001107410875282211	[289]	[285,277,262,251]	0	hSpCas9	negative selection	6225184
60371612	60371635	18	+	27260156	EWS502	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.21240547423168998	[638]	[541,887,770,970]	3	hSpCas9	negative selection	6282175
60371623	60371646	18	-	27260156	EWS502	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.4171702343415102	[23]	[95,94,53,17]	9	hSpCas9	negative selection	6282176
60372327	60372350	18	-	27260156	EWS502	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.501409225497767	[447]	[517,636,835,718]	8	hSpCas9	negative selection	6282177
60371828	60371851	18	-	27260156	EWS502	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.11616907896368714	[378]	[412,460,450,413]	2	hSpCas9	negative selection	6346433
60371383	60371406	18	-	27260156	EWS502	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5764789653212057	[2552]	[1515,2095,1819,1840]	-7	hSpCas9	negative selection	6346434
60371581	60371604	18	+	27260156	EWS502	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.3159410679573266	[289]	[399,366,382,375]	5	hSpCas9	negative selection	6346435
60371612	60371635	18	+	27260156	EW8	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.26276387876502505	[638]	[752,576,494,693]	5	hSpCas9	negative selection	6403426
60371623	60371646	18	-	27260156	EW8	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.8102079597122045	[23]	[81,102,52,38]	9	hSpCas9	negative selection	6403427
60372327	60372350	18	-	27260156	EW8	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.3350768992188386	[447]	[583,435,455,368]	6	hSpCas9	negative selection	6403428
60371828	60371851	18	-	27260156	EW8	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.12828461286906134	[378]	[443,330,251,340]	2	hSpCas9	negative selection	6467684
60371383	60371406	18	-	27260156	EW8	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5200619169041258	[2552]	[1870,1666,944,1416]	-7	hSpCas9	negative selection	6467685
60371581	60371604	18	+	27260156	EW8	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.4260943152677345	[289]	[228,294,382,333]	7	hSpCas9	negative selection	6467686
60371612	60371635	18	+	27260156	CORL105	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	-0.1595763423084569	[638]	[559,697,681,735]	-3	hSpCas9	negative selection	6524677
60371623	60371646	18	-	27260156	CORL105	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.1119615070958426	[23]	[78,80,33,44]	9	hSpCas9	negative selection	6524678
60372327	60372350	18	-	27260156	CORL105	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.41646555411257213	[447]	[711,767,736,587]	7	hSpCas9	negative selection	6524679
60371828	60371851	18	-	27260156	CORL105	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.2687231271069286	[378]	[412,428,728,594]	5	hSpCas9	negative selection	6588935
60371383	60371406	18	-	27260156	CORL105	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.44927637862505265	[2552]	[2472,2042,2442,1849]	-7	hSpCas9	negative selection	6588936
60371581	60371604	18	+	27260156	CORL105	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	-0.18491406675673017	[289]	[290,370,322,211]	-3	hSpCas9	negative selection	6588937
60371612	60371635	18	+	27260156	HS294T	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.6611165567429802	[638]	[455,326,404,364]	8	hSpCas9	negative selection	6645928
60371623	60371646	18	-	27260156	HS294T	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.755115406845532	[23]	[31,42,21,26]	9	hSpCas9	negative selection	6645929
60372327	60372350	18	-	27260156	HS294T	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.49265437636589204	[447]	[212,198,345,215]	6	hSpCas9	negative selection	6645930
60371828	60371851	18	-	27260156	HS294T	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.09926288195838065	[378]	[115,201,153,157]	1	hSpCas9	negative selection	6710186
60371383	60371406	18	-	27260156	HS294T	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.23958597309050722	[2552]	[684,919,868,887]	-3	hSpCas9	negative selection	6710187
60371581	60371604	18	+	27260156	HS294T	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.3255775812996138	[289]	[193,85,163,108]	4	hSpCas9	negative selection	6710188
60371612	60371635	18	+	27260156	HCC44	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.5144851681291712	[638]	[1039,943,1044,1104]	8	hSpCas9	negative selection	6767179
60371623	60371646	18	-	27260156	HCC44	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	2.124420936511579	[23]	[88,66,246,96]	9	hSpCas9	negative selection	6767180
60372327	60372350	18	-	27260156	HCC44	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.44912179816479963	[447]	[686,754,650,652]	7	hSpCas9	negative selection	6767181
60371828	60371851	18	-	27260156	HCC44	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	-0.2228563462256049	[378]	[360,235,510,399]	-4	hSpCas9	negative selection	6831437
60371383	60371406	18	-	27260156	HCC44	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5149303766763809	[2552]	[2011,1745,2729,1747]	-6	hSpCas9	negative selection	6831438
60371581	60371604	18	+	27260156	HCC44	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.4804272638857505	[289]	[359,337,840,364]	7	hSpCas9	negative selection	6831439
60371612	60371635	18	+	27260156	G402	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.2613366192833786	[638]	[654,1167,1039,848]	3	hSpCas9	negative selection	6888430
60371623	60371646	18	-	27260156	G402	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.68916540323236	[23]	[49,131,8,177]	9	hSpCas9	negative selection	6888431
60372327	60372350	18	-	27260156	G402	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.1279648341411224	[447]	[747,556,535,566]	1	hSpCas9	negative selection	6888432
60371828	60371851	18	-	27260156	G402	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.5695294443205868	[378]	[496,737,855,629]	7	hSpCas9	negative selection	6952688
60371383	60371406	18	-	27260156	G402	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.493502210715947	[2552]	[2617,2451,1702,2144]	-6	hSpCas9	negative selection	6952689
60371581	60371604	18	+	27260156	G402	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	-0.15679247284400566	[289]	[243,420,220,374]	-2	hSpCas9	negative selection	6952690
60371612	60371635	18	+	27260156	L33	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.10485353643897677	[638]	[664,253,549,590]	2	hSpCas9	negative selection	7009681
60371623	60371646	18	-	27260156	L33	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.1788434890509132	[23]	[78,22,22,44]	9	hSpCas9	negative selection	7009682
60372327	60372350	18	-	27260156	L33	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.025092096579745073	[447]	[424,217,263,446]	0	hSpCas9	negative selection	7009683
60371828	60371851	18	-	27260156	L33	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	-0.20755572185550453	[378]	[213,151,172,453]	-5	hSpCas9	negative selection	7073939
60371383	60371406	18	-	27260156	L33	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.4436892966705652	[2552]	[1568,794,1395,1787]	-8	hSpCas9	negative selection	7073940
60371581	60371604	18	+	27260156	L33	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	-0.19768526538319753	[289]	[185,96,152,345]	-4	hSpCas9	negative selection	7073941
60371612	60371635	18	+	27260156	K562	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.9246348998460414	[638]	[681,920,1471,1173]	9	hSpCas9	negative selection	7130932
60371623	60371646	18	-	27260156	K562	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.9523447965519987	[23]	[30,126,157,18]	9	hSpCas9	negative selection	7130933
60372327	60372350	18	-	27260156	K562	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.20393886209294726	[447]	[560,580,360,353]	2	hSpCas9	negative selection	7130934
60371828	60371851	18	-	27260156	K562	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.4557991783554741	[378]	[302,545,413,559]	6	hSpCas9	negative selection	7195190
60371383	60371406	18	-	27260156	K562	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.2149195009513849	[2552]	[2534,1807,2186,1377]	-3	hSpCas9	negative selection	7195191
60371581	60371604	18	+	27260156	K562	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.6806767031773027	[289]	[284,464,330,543]	8	hSpCas9	negative selection	7195192
60371612	60371635	18	+	27260156	HT29	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.22482595122672566	[638]	[1034,917,925,772]	4	hSpCas9	negative selection	7252183
60371623	60371646	18	-	27260156	HT29	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.751840718663356	[23]	[104,131,53,103]	9	hSpCas9	negative selection	7252184
60372327	60372350	18	-	27260156	HT29	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.42625541893980684	[447]	[717,708,680,801]	8	hSpCas9	negative selection	7252185
60371828	60371851	18	-	27260156	HT29	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.07125625659980611	[378]	[371,417,649,478]	1	hSpCas9	negative selection	7316441
60371383	60371406	18	-	27260156	HT29	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5780691183404825	[2552]	[2241,2308,2100,1724]	-7	hSpCas9	negative selection	7316442
60371581	60371604	18	+	27260156	HT29	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.3185125012445842	[289]	[449,384,598,330]	6	hSpCas9	negative selection	7316443
60371612	60371635	18	+	27260156	MHHES1	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.09232551497996933	[638]	[730,620,944,741]	1	hSpCas9	negative selection	7373434
60371623	60371646	18	-	27260156	MHHES1	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.5125270764730687	[23]	[199,26,26,64]	9	hSpCas9	negative selection	7373435
60372327	60372350	18	-	27260156	MHHES1	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.32914366151870045	[447]	[850,567,555,577]	6	hSpCas9	negative selection	7373436
60371828	60371851	18	-	27260156	MHHES1	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	-0.16256653870375876	[378]	[319,359,347,459]	-3	hSpCas9	negative selection	7437692
60371383	60371406	18	-	27260156	MHHES1	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.2879891623864519	[2552]	[2883,2881,2331,1570]	-5	hSpCas9	negative selection	7437693
60371581	60371604	18	+	27260156	MHHES1	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	-0.047839146509762176	[289]	[553,274,352,140]	-1	hSpCas9	negative selection	7437694
60371612	60371635	18	+	27260156	MEWO	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.20728143534271537	[638]	[782,568,736]	4	hSpCas9	negative selection	7494685
60371623	60371646	18	-	27260156	MEWO	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	0.9147021221473715	[23]	[36,30,57]	9	hSpCas9	negative selection	7494686
60372327	60372350	18	-	27260156	MEWO	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.005896124423304991	[447]	[569,286,434]	0	hSpCas9	negative selection	7494687
60371828	60371851	18	-	27260156	MEWO	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.01511083447306888	[378]	[551,230,329]	0	hSpCas9	negative selection	7558943
60371383	60371406	18	-	27260156	MEWO	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.6125662918175485	[2552]	[1757,1365,1600]	-8	hSpCas9	negative selection	7558944
60371581	60371604	18	+	27260156	MEWO	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	-0.038975044729909536	[289]	[333,208,262]	-1	hSpCas9	negative selection	7558945
60371612	60371635	18	+	27260156	LNCAPCLONEFGC	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.19499047211844023	[638]	[647,624,825,577]	3	hSpCas9	negative selection	7615936
60371623	60371646	18	-	27260156	LNCAPCLONEFGC	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.10663444704522	[23]	[23,32,89,47]	9	hSpCas9	negative selection	7615937
60372327	60372350	18	-	27260156	LNCAPCLONEFGC	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.40806245933083934	[447]	[410,595,529,613]	6	hSpCas9	negative selection	7615938
60371828	60371851	18	-	27260156	LNCAPCLONEFGC	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	-0.1482990210962692	[378]	[204,382,335,315]	-2	hSpCas9	negative selection	7680194
60371383	60371406	18	-	27260156	LNCAPCLONEFGC	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.7111729957479973	[2552]	[1176,1233,1702,1594]	-8	hSpCas9	negative selection	7680195
60371581	60371604	18	+	27260156	LNCAPCLONEFGC	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.23933165349676228	[289]	[307,378,345,207]	4	hSpCas9	negative selection	7680196
60371612	60371635	18	+	27260156	PANC0327	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.31616418700636106	[638]	[850,586,749,665]	5	hSpCas9	negative selection	7737187
60371623	60371646	18	-	27260156	PANC0327	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.5479075321425748	[23]	[42,52,92,59]	9	hSpCas9	negative selection	7737188
60372327	60372350	18	-	27260156	PANC0327	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.2811535037196992	[447]	[292,603,476,528]	4	hSpCas9	negative selection	7737189
60371828	60371851	18	-	27260156	PANC0327	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.7361556887537701	[378]	[527,285,734,726]	9	hSpCas9	negative selection	7801445
60371383	60371406	18	-	27260156	PANC0327	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.22987180551080355	[2552]	[2361,1567,1502,2382]	-3	hSpCas9	negative selection	7801446
60371581	60371604	18	+	27260156	PANC0327	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	-0.2774929321511497	[289]	[220,333,135,143]	-4	hSpCas9	negative selection	7801447
60371612	60371635	18	+	27260156	NCIH2009	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.19715921811923298	[638]	[1295,950,876]	2	hSpCas9	negative selection	7858438
60371623	60371646	18	-	27260156	NCIH2009	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	2.107715438424142	[23]	[102,40,282]	9	hSpCas9	negative selection	7858439
60372327	60372350	18	-	27260156	NCIH2009	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.6435193371136344	[447]	[1230,852,899]	8	hSpCas9	negative selection	7858440
60371828	60371851	18	-	27260156	NCIH2009	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.020395721974026282	[378]	[493,578,527]	0	hSpCas9	negative selection	7922696
60371383	60371406	18	-	27260156	NCIH2009	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.1837307846594327	[2552]	[3598,2840,3071]	-3	hSpCas9	negative selection	7922697
60371581	60371604	18	+	27260156	NCIH2009	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.27345120235561277	[289]	[696,287,527]	4	hSpCas9	negative selection	7922698
60371612	60371635	18	+	27260156	NCIH1373	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.6062482188991376	[638]	[1323,1055,807,320]	6	hSpCas9	negative selection	7979689
60371623	60371646	18	-	27260156	NCIH1373	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.4934266464241301	[23]	[73,158,41,3]	9	hSpCas9	negative selection	7979690
60372327	60372350	18	-	27260156	NCIH1373	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.4385382652454362	[447]	[572,519,634,265]	4	hSpCas9	negative selection	7979691
60371828	60371851	18	-	27260156	NCIH1373	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.6005117066371632	[378]	[638,567,304,289]	6	hSpCas9	negative selection	8043947
60371383	60371406	18	-	27260156	NCIH1373	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.019336676553755705	[2552]	[3458,1890,2875,861]	0	hSpCas9	negative selection	8043948
60371581	60371604	18	+	27260156	NCIH1373	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.9136652995599841	[289]	[514,716,802,95]	8	hSpCas9	negative selection	8043949
60371612	60371635	18	+	27260156	PATU8902	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.6041922652452181	[638]	[1190,1515,1045,1780]	6	hSpCas9	negative selection	8100940
60371623	60371646	18	-	27260156	PATU8902	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	2.239311242508542	[23]	[116,208,162,137]	9	hSpCas9	negative selection	8100941
60372327	60372350	18	-	27260156	PATU8902	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.21987948849177857	[447]	[566,729,574,1116]	2	hSpCas9	negative selection	8100942
60371828	60371851	18	-	27260156	PATU8902	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.8221824379226974	[378]	[907,1102,519,1352]	8	hSpCas9	negative selection	8165198
60371383	60371406	18	-	27260156	PATU8902	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.6016568474847155	[2552]	[2408,1845,2279,2898]	-5	hSpCas9	negative selection	8165199
60371581	60371604	18	+	27260156	PATU8902	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.23767375035632787	[289]	[300,478,189,1079]	2	hSpCas9	negative selection	8165200
60371612	60371635	18	+	27260156	PANC1	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	-0.11425736208623577	[638]	[482,706,507,383]	-2	hSpCas9	negative selection	8222191
60371623	60371646	18	-	27260156	PANC1	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.212184398172631	[23]	[30,95,29,43]	9	hSpCas9	negative selection	8222192
60372327	60372350	18	-	27260156	PANC1	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.32982347622727937	[447]	[423,524,527,462]	5	hSpCas9	negative selection	8222193
60371828	60371851	18	-	27260156	PANC1	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.23159266871698336	[378]	[321,652,266,342]	3	hSpCas9	negative selection	8286449
60371383	60371406	18	-	27260156	PANC1	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5812029031265771	[2552]	[1291,2087,1485,1155]	-7	hSpCas9	negative selection	8286450
60371581	60371604	18	+	27260156	PANC1	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.557803201628739	[289]	[279,719,210,328]	8	hSpCas9	negative selection	8286451
60371612	60371635	18	+	27260156	PANC0813	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.14459869355025368	[638]	[725,876,838,863]	2	hSpCas9	negative selection	8343442
60371623	60371646	18	-	27260156	PANC0813	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.3739191617127626	[23]	[75,64,87,63]	9	hSpCas9	negative selection	8343443
60372327	60372350	18	-	27260156	PANC0813	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.352716076298906	[447]	[581,764,686,645]	5	hSpCas9	negative selection	8343444
60371828	60371851	18	-	27260156	PANC0813	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.04826406133008959	[378]	[450,582,394,412]	0	hSpCas9	negative selection	8407700
60371383	60371406	18	-	27260156	PANC0813	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.2938904700948126	[2552]	[2728,2867,2048,2173]	-5	hSpCas9	negative selection	8407701
60371581	60371604	18	+	27260156	PANC0813	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.09571000476207903	[289]	[480,261,439,287]	1	hSpCas9	negative selection	8407702
60371612	60371635	18	+	27260156	RDES	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.42466068452796035	[638]	[900,709,1147,1246]	6	hSpCas9	negative selection	8464693
60371623	60371646	18	-	27260156	RDES	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.2732272085596907	[23]	[40,137,39,38]	9	hSpCas9	negative selection	8464694
60372327	60372350	18	-	27260156	RDES	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.5023678533672641	[447]	[653,587,818,893]	7	hSpCas9	negative selection	8464695
60371828	60371851	18	-	27260156	RDES	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.3681622565300817	[378]	[460,362,800,676]	6	hSpCas9	negative selection	8528951
60371383	60371406	18	-	27260156	RDES	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.4914244696819856	[2552]	[1594,1957,2281,2673]	-7	hSpCas9	negative selection	8528952
60371581	60371604	18	+	27260156	RDES	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.46189960506065647	[289]	[401,513,366,557]	7	hSpCas9	negative selection	8528953
60371612	60371635	18	+	27260156	PC3	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.23368511022034033	[638]	[382,680,1369,914]	5	hSpCas9	negative selection	8585944
60371623	60371646	18	-	27260156	PC3	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.4403864804732884	[23]	[75,54,74,40]	9	hSpCas9	negative selection	8585945
60372327	60372350	18	-	27260156	PC3	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.2720622279715041	[447]	[296,596,1037,471]	6	hSpCas9	negative selection	8585946
60371828	60371851	18	-	27260156	PC3	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	-0.11076360806860103	[378]	[183,297,624,450]	-2	hSpCas9	negative selection	8650202
60371383	60371406	18	-	27260156	PC3	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.7764004124846484	[2552]	[1006,1323,2396,1640]	-9	hSpCas9	negative selection	8650203
60371581	60371604	18	+	27260156	PC3	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.16429921388590607	[289]	[245,257,596,300]	3	hSpCas9	negative selection	8650204
60371612	60371635	18	+	27260156	PATU8988T	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.5298799386535414	[638]	[509,924,857,1309]	8	hSpCas9	negative selection	8707195
60371623	60371646	18	-	27260156	PATU8988T	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	0.9951478339186077	[23]	[22,18,109,27]	9	hSpCas9	negative selection	8707196
60372327	60372350	18	-	27260156	PATU8988T	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.609826785503185	[447]	[746,714,559,623]	8	hSpCas9	negative selection	8707197
60371828	60371851	18	-	27260156	PATU8988T	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	-0.02116937836165489	[378]	[363,457,288,340]	0	hSpCas9	negative selection	8771453
60371383	60371406	18	-	27260156	PATU8988T	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5745505385416503	[2552]	[1360,1650,1710,1922]	-7	hSpCas9	negative selection	8771454
60371581	60371604	18	+	27260156	PATU8988T	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.3285955381093923	[289]	[283,427,425,268]	5	hSpCas9	negative selection	8771455
60371612	60371635	18	+	27260156	T47D	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.16840529179507624	[638]	[925,717,899,810]	3	hSpCas9	negative selection	8828446
60371623	60371646	18	-	27260156	T47D	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.3611184122128326	[23]	[54,53,90,88]	9	hSpCas9	negative selection	8828447
60372327	60372350	18	-	27260156	T47D	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.3507542929923275	[447]	[716,590,699,659]	7	hSpCas9	negative selection	8828448
60371828	60371851	18	-	27260156	T47D	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.19654991801804675	[378]	[530,426,560,510]	4	hSpCas9	negative selection	8892704
60371383	60371406	18	-	27260156	T47D	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5800688194166359	[2552]	[2050,1724,2156,2046]	-8	hSpCas9	negative selection	8892705
60371581	60371604	18	+	27260156	T47D	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	-0.021598922720663993	[289]	[354,325,360,287]	0	hSpCas9	negative selection	8892706
60371612	60371635	18	+	27260156	SU8686	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.21090145532045812	[638]	[668,646,837,806]	3	hSpCas9	negative selection	8949697
60371623	60371646	18	-	27260156	SU8686	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	2.2814882305470015	[23]	[69,124,87,194]	9	hSpCas9	negative selection	8949698
60372327	60372350	18	-	27260156	SU8686	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.352788805518951	[447]	[434,506,638,735]	6	hSpCas9	negative selection	8949699
60371828	60371851	18	-	27260156	SU8686	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.14804983143773812	[378]	[232,315,574,607]	2	hSpCas9	negative selection	9013955
60371383	60371406	18	-	27260156	SU8686	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.42287414299846704	[2552]	[1822,1517,1945,2389]	-6	hSpCas9	negative selection	9013956
60371581	60371604	18	+	27260156	SU8686	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.3307798141784271	[289]	[309,390,323,430]	5	hSpCas9	negative selection	9013957
60371612	60371635	18	+	27260156	SKES1	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	-0.08969648461571961	[638]	[733,572,598,509]	-2	hSpCas9	negative selection	9070948
60371623	60371646	18	-	27260156	SKES1	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.4410596945319534	[23]	[59,58,75,62]	9	hSpCas9	negative selection	9070949
60372327	60372350	18	-	27260156	SKES1	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.3973357702461043	[447]	[741,614,608,425]	7	hSpCas9	negative selection	9070950
60371828	60371851	18	-	27260156	SKES1	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	-0.09938042285281407	[378]	[325,384,384,315]	-2	hSpCas9	negative selection	9135206
60371383	60371406	18	-	27260156	SKES1	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.601744892118552	[2552]	[2075,1970,1531,1258]	-8	hSpCas9	negative selection	9135207
60371581	60371604	18	+	27260156	SKES1	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.14896632200755577	[289]	[226,500,288,276]	3	hSpCas9	negative selection	9135208
60371612	60371635	18	+	27260156	TOV112D	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.27059743317923146	[638]	[953,956,657,583]	5	hSpCas9	negative selection	9192199
60371623	60371646	18	-	27260156	TOV112D	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.8914729910659225	[23]	[34,43,103,155]	9	hSpCas9	negative selection	9192200
60372327	60372350	18	-	27260156	TOV112D	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.28325199002037943	[447]	[411,661,526,597]	5	hSpCas9	negative selection	9192201
60371828	60371851	18	-	27260156	TOV112D	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	-0.101745772708702	[378]	[312,508,267,358]	-2	hSpCas9	negative selection	9256457
60371383	60371406	18	-	27260156	TOV112D	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5477874621092309	[2552]	[1627,2394,1573,1550]	-8	hSpCas9	negative selection	9256458
60371581	60371604	18	+	27260156	TOV112D	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	-0.057818889662814454	[289]	[453,235,192,237]	-1	hSpCas9	negative selection	9256459
60371612	60371635	18	+	27260156	TC71	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.22289493050892017	[638]	[663,691,895,954]	5	hSpCas9	negative selection	9313450
60371623	60371646	18	-	27260156	TC71	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.7523265254457332	[23]	[84,93,119,43]	9	hSpCas9	negative selection	9313451
60372327	60372350	18	-	27260156	TC71	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.3795044818250178	[447]	[712,630,490,668]	8	hSpCas9	negative selection	9313452
60371828	60371851	18	-	27260156	TC71	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.19841205603944895	[378]	[412,444,572,428]	5	hSpCas9	negative selection	9377708
60371383	60371406	18	-	27260156	TC71	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.4983598767213484	[2552]	[1887,2009,1844,2014]	-8	hSpCas9	negative selection	9377709
60371581	60371604	18	+	27260156	TC71	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	-0.1014162741105431	[289]	[296,326,288,242]	-3	hSpCas9	negative selection	9377710
60371612	60371635	18	+	27260156	TC32	viability	GGTAATCGCTCCCTTCATATTGG	MC4R	ENSG00000166603	0.2786424605866419	[638]	[675,606,983,696]	5	hSpCas9	negative selection	9434701
60371623	60371646	18	-	27260156	TC32	viability	CCGCCAAGGTGCCAATATGAAGG	MC4R	ENSG00000166603	1.5186078946750703	[23]	[48,74,87,42]	9	hSpCas9	negative selection	9434702
60372327	60372350	18	-	27260156	TC32	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.4750853828756074	[447]	[492,411,801,722]	7	hSpCas9	negative selection	9434703
60371828	60371851	18	-	27260156	TC32	viability	GGATCATCATAAGTTGTATCTGG	MC4R	ENSG00000166603	0.20000669363750495	[378]	[298,424,475,430]	3	hSpCas9	negative selection	9498959
60371383	60371406	18	-	27260156	TC32	viability	GATCATCTGTTGCTATCCCCTGG	MC4R	ENSG00000166603	-0.5801294739456215	[2552]	[1625,1114,2128,1734]	-8	hSpCas9	negative selection	9498960
60371581	60371604	18	+	27260156	TC32	viability	AGACAACAAAGACGCCAATCAGG	MC4R	ENSG00000166603	0.04724656894588797	[289]	[317,255,279,256]	0	hSpCas9	negative selection	9498961
60371367	60371390	18	+	27869803	HPAFII	viability after 27 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.1787573715977896	[173]	[162,53,NaN]	1	hSpCas9	negative selection	9564867
60371911	60371934	18	+	27869803	HPAFII	viability after 27 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.7726598775483591	[424]	[462,313,NaN]	6	hSpCas9	negative selection	9564868
60372286	60372309	18	+	27869803	HPAFII	viability after 27 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.2244365273062332	[266]	[169,158,NaN]	1	hSpCas9	negative selection	9564869
60371367	60371390	18	+	27869803	HPAFII	viability after 15 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.3944357697563238	[173]	[267,231,NaN]	4	hSpCas9	negative selection	9647316
60371911	60371934	18	+	27869803	HPAFII	viability after 15 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.496114267862946	[424]	[843,519,NaN]	5	hSpCas9	negative selection	9647317
60372286	60372309	18	+	27869803	HPAFII	viability after 15 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	-0.16425209201837315	[266]	[334,206,NaN]	-2	hSpCas9	negative selection	9647318
60371367	60371390	18	+	27869803	ASPC1	viability after 36 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.3397102931948408	[447]	[75,39,221]	-3	hSpCas9	negative selection	9729765
60371911	60371934	18	+	27869803	ASPC1	viability after 36 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.20754743147148091	[1122]	[728,424,275]	2	hSpCas9	negative selection	9729766
60372286	60372309	18	+	27869803	ASPC1	viability after 36 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	1.130196021107686	[641]	[708,171,584]	9	hSpCas9	negative selection	9729767
60371367	60371390	18	+	27869803	PATU8988S	viability after 35 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.5034109053502218	[391]	[355,90,NaN]	5	hSpCas9	negative selection	9812214
60371911	60371934	18	+	27869803	PATU8988S	viability after 35 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	1.0721478875054375	[869]	[614,858,NaN]	9	hSpCas9	negative selection	9812215
60372286	60372309	18	+	27869803	PATU8988S	viability after 35 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	-0.02360006549841112	[569]	[156,294,NaN]	0	hSpCas9	negative selection	9812216
60371367	60371390	18	+	27869803	PATU8988S	viability after 31 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.33390880042663207	[391]	[262,112,NaN]	4	hSpCas9	negative selection	9894663
60371911	60371934	18	+	27869803	PATU8988S	viability after 31 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.6938257228780835	[869]	[488,652,NaN]	7	hSpCas9	negative selection	9894664
60372286	60372309	18	+	27869803	PATU8988S	viability after 31 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.43161113555058905	[569]	[240,389,NaN]	5	hSpCas9	negative selection	9894665
60371367	60371390	18	+	27869803	HPAFII	viability after 35 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.5700847466125989	[173]	[150,107,NaN]	4	hSpCas9	negative selection	9977112
60371911	60371934	18	+	27869803	HPAFII	viability after 35 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	1.0929832012408665	[424]	[489,423,NaN]	7	hSpCas9	negative selection	9977113
60372286	60372309	18	+	27869803	HPAFII	viability after 35 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.18936357998086745	[266]	[171,133,NaN]	1	hSpCas9	negative selection	9977114
60371367	60371390	18	+	27869803	HPAFII	viability after 31 days	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.7587470736650517	[173]	[214,110,NaN]	5	hSpCas9	negative selection	10059561
60371911	60371934	18	+	27869803	HPAFII	viability after 31 days	TGTCCACTGCAATTGAAAGCAGG	MC4R	ENSG00000166603	0.822125380041965	[424]	[481,355,NaN]	6	hSpCas9	negative selection	10059562
60372286	60372309	18	+	27869803	HPAFII	viability after 31 days	TGTAACTGCTGCGGTTCCAGAGG	MC4R	ENSG00000166603	0.05721848412085939	[266]	[164,145,NaN]	0	hSpCas9	negative selection	10059563
60372313	60372336	18	+	28162770	P31FUJ	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-0.6396564994451949	[292]	[220]	-5	hSpCas9	negative selection	10189985
60372249	60372272	18	-	28162770	P31FUJ	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	0.5329267266236191	[436]	[742]	6	hSpCas9	negative selection	10189986
60371644	60371667	18	+	28162770	P31FUJ	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-0.259519542790158	[108]	[106]	-2	hSpCas9	negative selection	10189987
60372327	60372350	18	-	28162770	P31FUJ	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.7012002368113811	[122]	[234]	7	hSpCas9	negative selection	10189988
60371367	60371390	18	+	28162770	P31FUJ	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.15798774861778808	[89]	[117]	1	hSpCas9	negative selection	10189989
60372277	60372300	18	+	28162770	P31FUJ	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.7121992594890285	[654]	[1260]	7	hSpCas9	negative selection	10189990
60372234	60372257	18	-	28162770	P31FUJ	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.1795209101674291	[531]	[707]	2	hSpCas9	negative selection	10189991
60371914	60371937	18	-	28162770	P31FUJ	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.7204709499205009	[705]	[1366]	8	hSpCas9	negative selection	10189992
60371591	60371614	18	+	28162770	P31FUJ	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	-0.5821364566423928	[185]	[145]	-5	hSpCas9	negative selection	10189993
60371689	60371712	18	+	28162770	P31FUJ	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	0.019384819182423074	[88]	[105]	0	hSpCas9	negative selection	10189994
60372313	60372336	18	+	28162770	TF1	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10359351
60372249	60372272	18	-	28162770	TF1	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	NaN	[NaN]	[443]	1	hSpCas9	negative selection	10359352
60371644	60371667	18	+	28162770	TF1	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10359353
60372327	60372350	18	-	28162770	TF1	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10359354
60371367	60371390	18	+	28162770	TF1	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10359355
60372277	60372300	18	+	28162770	TF1	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	NaN	[NaN]	[456]	1	hSpCas9	negative selection	10359356
60372234	60372257	18	-	28162770	TF1	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	NaN	[NaN]	[399]	1	hSpCas9	negative selection	10359357
60371914	60371937	18	-	28162770	TF1	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	NaN	[NaN]	[714]	1	hSpCas9	negative selection	10359358
60371591	60371614	18	+	28162770	TF1	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	NaN	[NaN]	[194]	1	hSpCas9	negative selection	10359359
60371689	60371712	18	+	28162770	TF1	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10359360
60372313	60372336	18	+	28162770	SKM1	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-0.49305317545687066	[81]	[102]	-4	hSpCas9	negative selection	10528717
60372249	60372272	18	-	28162770	SKM1	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	1.6142934218173572	[79]	[432]	9	hSpCas9	negative selection	10528718
60371644	60371667	18	+	28162770	SKM1	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-0.13394570433674602	[17]	[28]	-1	hSpCas9	negative selection	10528719
60372327	60372350	18	-	28162770	SKM1	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.11386796455827883	[45]	[87]	1	hSpCas9	negative selection	10528720
60371367	60371390	18	+	28162770	SKM1	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.30116953472056496	[22]	[32]	-3	hSpCas9	negative selection	10528721
60372277	60372300	18	+	28162770	SKM1	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.31176749653104574	[210]	[462]	3	hSpCas9	negative selection	10528722
60372234	60372257	18	-	28162770	SKM1	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	-0.3239748340721301	[113]	[160]	-3	hSpCas9	negative selection	10528723
60371914	60371937	18	-	28162770	SKM1	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	1.2854218849592214	[151]	[654]	9	hSpCas9	negative selection	10528724
60371591	60371614	18	+	28162770	SKM1	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	1.2858015915125092	[28]	[124]	9	hSpCas9	negative selection	10528725
60371689	60371712	18	+	28162770	SKM1	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	0.4410327078117884	[19]	[47]	4	hSpCas9	negative selection	10528726
60372313	60372336	18	+	28162770	SKM1	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-0.49305317545687066	[81]	[102]	-4	hSpCas9	negative selection	10698083
60372249	60372272	18	-	28162770	SKM1	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	1.6142934218173572	[79]	[432]	9	hSpCas9	negative selection	10698084
60371644	60371667	18	+	28162770	SKM1	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-0.13394570433674602	[17]	[28]	-1	hSpCas9	negative selection	10698085
60372327	60372350	18	-	28162770	SKM1	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.11386796455827883	[45]	[87]	1	hSpCas9	negative selection	10698086
60371367	60371390	18	+	28162770	SKM1	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.30116953472056496	[22]	[32]	-3	hSpCas9	negative selection	10698087
60372277	60372300	18	+	28162770	SKM1	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.31176749653104574	[210]	[462]	3	hSpCas9	negative selection	10698088
60372234	60372257	18	-	28162770	SKM1	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	-0.3239748340721301	[113]	[160]	-3	hSpCas9	negative selection	10698089
60371914	60371937	18	-	28162770	SKM1	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	1.2854218849592214	[151]	[654]	9	hSpCas9	negative selection	10698090
60371591	60371614	18	+	28162770	SKM1	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	1.2858015915125092	[28]	[124]	9	hSpCas9	negative selection	10698091
60371689	60371712	18	+	28162770	SKM1	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	0.4410327078117884	[19]	[47]	4	hSpCas9	negative selection	10698092
60372313	60372336	18	+	28162770	PL21	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	0.055516051409867595	[324]	[146]	0	hSpCas9	negative selection	10867449
60372249	60372272	18	-	28162770	PL21	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	1.5135919273093374	[238]	[296]	9	hSpCas9	negative selection	10867450
60371644	60371667	18	+	28162770	PL21	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	1.5960682908204595	[113]	[149]	9	hSpCas9	negative selection	10867451
60372327	60372350	18	-	28162770	PL21	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.3103225322397431	[125]	[67]	2	hSpCas9	negative selection	10867452
60371367	60371390	18	+	28162770	PL21	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.20013961448932016	[131]	[65]	1	hSpCas9	negative selection	10867453
60372277	60372300	18	+	28162770	PL21	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.6721550545963368	[632]	[438]	6	hSpCas9	negative selection	10867454
60372234	60372257	18	-	28162770	PL21	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.8075569660381722	[339]	[258]	7	hSpCas9	negative selection	10867455
60371914	60371937	18	-	28162770	PL21	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.37613106412599406	[500]	[282]	3	hSpCas9	negative selection	10867456
60371591	60371614	18	+	28162770	PL21	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	0.4166314343860836	[104]	[60]	3	hSpCas9	negative selection	10867457
60371689	60371712	18	+	28162770	PL21	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	-0.14944482330090736	[78]	[30]	-1	hSpCas9	negative selection	10867458
60372313	60372336	18	+	28162770	P31FUJ	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-0.6396564994451949	[292]	[220]	-5	hSpCas9	negative selection	11036815
60372249	60372272	18	-	28162770	P31FUJ	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	0.5329267266236191	[436]	[742]	6	hSpCas9	negative selection	11036816
60371644	60371667	18	+	28162770	P31FUJ	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-0.259519542790158	[108]	[106]	-2	hSpCas9	negative selection	11036817
60372327	60372350	18	-	28162770	P31FUJ	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.7012002368113811	[122]	[234]	7	hSpCas9	negative selection	11036818
60371367	60371390	18	+	28162770	P31FUJ	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.15798774861778808	[89]	[117]	1	hSpCas9	negative selection	11036819
60372277	60372300	18	+	28162770	P31FUJ	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.7121992594890285	[654]	[1260]	7	hSpCas9	negative selection	11036820
60372234	60372257	18	-	28162770	P31FUJ	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.1795209101674291	[531]	[707]	2	hSpCas9	negative selection	11036821
60371914	60371937	18	-	28162770	P31FUJ	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.7204709499205009	[705]	[1366]	8	hSpCas9	negative selection	11036822
60371591	60371614	18	+	28162770	P31FUJ	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	-0.5821364566423928	[185]	[145]	-5	hSpCas9	negative selection	11036823
60371689	60371712	18	+	28162770	P31FUJ	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	0.019384819182423074	[88]	[105]	0	hSpCas9	negative selection	11036824
60372313	60372336	18	+	28162770	OCIAML5	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-0.48851938677489565	[163]	[210]	-3	hSpCas9	negative selection	11206181
60372249	60372272	18	-	28162770	OCIAML5	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	0.4388346284027409	[234]	[574]	4	hSpCas9	negative selection	11206182
60371644	60371667	18	+	28162770	OCIAML5	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	0.526445052389733	[29]	[77]	4	hSpCas9	negative selection	11206183
60372327	60372350	18	-	28162770	OCIAML5	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	1.0983514002854426	[73]	[285]	8	hSpCas9	negative selection	11206184
60371367	60371390	18	+	28162770	OCIAML5	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	0.9884552151288066	[42]	[153]	8	hSpCas9	negative selection	11206185
60372277	60372300	18	+	28162770	OCIAML5	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.5895317546859817	[295]	[803]	5	hSpCas9	negative selection	11206186
60372234	60372257	18	-	28162770	OCIAML5	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.13059611270299176	[292]	[578]	1	hSpCas9	negative selection	11206187
60371914	60371937	18	-	28162770	OCIAML5	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	1.134709733979838	[273]	[1085]	8	hSpCas9	negative selection	11206188
60371591	60371614	18	+	28162770	OCIAML5	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	1.7661720847314575	[49]	[306]	9	hSpCas9	negative selection	11206189
60371689	60371712	18	+	28162770	OCIAML5	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	0.31429181555812313	[44]	[100]	2	hSpCas9	negative selection	11206190
60372313	60372336	18	+	28162770	EOL1	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-1.3480726830924572	[603]	[124]	-7	hSpCas9	negative selection	11375547
60372249	60372272	18	-	28162770	EOL1	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	-0.37648509900547794	[376]	[152]	-3	hSpCas9	negative selection	11375548
60371644	60371667	18	+	28162770	EOL1	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-1.5832468686281618	[181]	[31]	-7	hSpCas9	negative selection	11375549
60372327	60372350	18	-	28162770	EOL1	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	-0.32783939006375085	[242]	[101]	-2	hSpCas9	negative selection	11375550
60371367	60371390	18	+	28162770	EOL1	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.13375086899413258	[201]	[96]	-1	hSpCas9	negative selection	11375551
60372277	60372300	18	+	28162770	EOL1	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.24073188392309275	[1207]	[751]	2	hSpCas9	negative selection	11375552
60372234	60372257	18	-	28162770	EOL1	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.28161767257815384	[583]	[373]	2	hSpCas9	negative selection	11375553
60371914	60371937	18	-	28162770	EOL1	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	1.1157721748133032	[761]	[869]	8	hSpCas9	negative selection	11375554
60371591	60371614	18	+	28162770	EOL1	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	0.8139037078865421	[148]	[137]	7	hSpCas9	negative selection	11375555
60371689	60371712	18	+	28162770	EOL1	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	1.872080351676399	[69]	[134]	9	hSpCas9	negative selection	11375556
60372313	60372336	18	+	28162770	MOLM13	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-0.8978831298784733	[450]	[174]	-5	hSpCas9	negative selection	11544913
60372249	60372272	18	-	28162770	MOLM13	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	0.4199093526427573	[427]	[413]	3	hSpCas9	negative selection	11544914
60371644	60371667	18	+	28162770	MOLM13	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-0.06617222087653951	[180]	[124]	0	hSpCas9	negative selection	11544915
60372327	60372350	18	-	28162770	MOLM13	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	1.9323291208996936	[182]	[504]	9	hSpCas9	negative selection	11544916
60371367	60371390	18	+	28162770	MOLM13	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	1.0626329030583204	[146]	[221]	7	hSpCas9	negative selection	11544917
60372277	60372300	18	+	28162770	MOLM13	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.8070004881052983	[867]	[1097]	6	hSpCas9	negative selection	11544918
60372234	60372257	18	-	28162770	MOLM13	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.9368858642174099	[491]	[680]	7	hSpCas9	negative selection	11544919
60371914	60371937	18	-	28162770	MOLM13	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.8162034650785719	[790]	[1006]	6	hSpCas9	negative selection	11544920
60371591	60371614	18	+	28162770	MOLM13	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	-1.0953780480772586	[197]	[66]	-5	hSpCas9	negative selection	11544921
60371689	60371712	18	+	28162770	MOLM13	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	0.6433313879544571	[115]	[130]	5	hSpCas9	negative selection	11544922
60372313	60372336	18	+	28162770	HEL	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	0.10704387619589706	[402]	[277]	0	hSpCas9	negative selection	11714279
60372249	60372272	18	-	28162770	HEL	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	1.1433277753944142	[310]	[439]	8	hSpCas9	negative selection	11714280
60371644	60371667	18	+	28162770	HEL	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	0.3269629640945899	[116]	[93]	2	hSpCas9	negative selection	11714281
60372327	60372350	18	-	28162770	HEL	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.9753141710872278	[161]	[203]	8	hSpCas9	negative selection	11714282
60371367	60371390	18	+	28162770	HEL	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.3370832860620129	[141]	[71]	-2	hSpCas9	negative selection	11714283
60372277	60372300	18	+	28162770	HEL	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	1.2610485899099502	[726]	[1115]	9	hSpCas9	negative selection	11714284
60372234	60372257	18	-	28162770	HEL	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.4559962124977708	[452]	[397]	4	hSpCas9	negative selection	11714285
60371914	60371937	18	-	28162770	HEL	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.27500704749987004	[639]	[495]	2	hSpCas9	negative selection	11714286
60371591	60371614	18	+	28162770	HEL	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	-0.15081029053221662	[129]	[74]	-1	hSpCas9	negative selection	11714287
60371689	60371712	18	+	28162770	HEL	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	0.07767588871690556	[107]	[72]	0	hSpCas9	negative selection	11714288
60372313	60372336	18	+	28162770	MV411	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-1.0312784772832881	[295]	[121]	-6	hSpCas9	negative selection	11883645
60372249	60372272	18	-	28162770	MV411	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	1.043146935821638	[230]	[400]	8	hSpCas9	negative selection	11883646
60371644	60371667	18	+	28162770	MV411	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-0.1494526017858091	[78]	[59]	-1	hSpCas9	negative selection	11883647
60372327	60372350	18	-	28162770	MV411	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.892209446739235	[125]	[196]	7	hSpCas9	negative selection	11883648
60371367	60371390	18	+	28162770	MV411	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	1.0262233206436087	[101]	[174]	8	hSpCas9	negative selection	11883649
60372277	60372300	18	+	28162770	MV411	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.5465737807968951	[637]	[784]	5	hSpCas9	negative selection	11883650
60372234	60372257	18	-	28162770	MV411	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	1.0939166296954719	[316]	[569]	8	hSpCas9	negative selection	11883651
60371914	60371937	18	-	28162770	MV411	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.9134366235948379	[524]	[832]	7	hSpCas9	negative selection	11883652
60371591	60371614	18	+	28162770	MV411	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	0.49387544608587414	[101]	[120]	4	hSpCas9	negative selection	11883653
60371689	60371712	18	+	28162770	MV411	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	0.8229397222548651	[50]	[75]	7	hSpCas9	negative selection	11883654
60372313	60372336	18	+	28162770	MONOMAC1	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	0.2917103384022993	[185]	[260]	3	hSpCas9	negative selection	12053011
60372249	60372272	18	-	28162770	MONOMAC1	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	-0.1655012736264468	[180]	[184]	-1	hSpCas9	negative selection	12053012
60371644	60371667	18	+	28162770	MONOMAC1	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-0.1970368470595537	[81]	[81]	-2	hSpCas9	negative selection	12053013
60372327	60372350	18	-	28162770	MONOMAC1	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	0.7205009927484733	[89]	[169]	7	hSpCas9	negative selection	12053014
60371367	60371390	18	+	28162770	MONOMAC1	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.24887577857917187	[84]	[81]	-2	hSpCas9	negative selection	12053015
60372277	60372300	18	+	28162770	MONOMAC1	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.6423792842303488	[355]	[636]	6	hSpCas9	negative selection	12053016
60372234	60372257	18	-	28162770	MONOMAC1	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.7975899808415947	[268]	[535]	7	hSpCas9	negative selection	12053017
60371914	60371937	18	-	28162770	MONOMAC1	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.19743932973697387	[317]	[417]	2	hSpCas9	negative selection	12053018
60371591	60371614	18	+	28162770	MONOMAC1	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	1.529281502907144	[67]	[224]	9	hSpCas9	negative selection	12053019
60371689	60371712	18	+	28162770	MONOMAC1	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	0.6654596291905113	[32]	[59]	6	hSpCas9	negative selection	12053020
60372313	60372336	18	+	28162770	OCIAML2	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-0.9073623956203242	[66]	[197]	-6	hSpCas9	negative selection	12222377
60372249	60372272	18	-	28162770	OCIAML2	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	0.7772976882014243	[39]	[379]	7	hSpCas9	negative selection	12222378
60371644	60371667	18	+	28162770	OCIAML2	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-0.17644672083770307	[20]	[102]	-1	hSpCas9	negative selection	12222379
60372327	60372350	18	-	28162770	OCIAML2	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	-0.3710941516912468	[27]	[119]	-3	hSpCas9	negative selection	12222380
60371367	60371390	18	+	28162770	OCIAML2	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.7402368849994412	[21]	[72]	-5	hSpCas9	negative selection	12222381
60372277	60372300	18	+	28162770	OCIAML2	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.12581524352628737	[145]	[882]	1	hSpCas9	negative selection	12222382
60372234	60372257	18	-	28162770	OCIAML2	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.35116660920392895	[70]	[501]	3	hSpCas9	negative selection	12222383
60371914	60371937	18	-	28162770	OCIAML2	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.695767802704826	[90]	[816]	6	hSpCas9	negative selection	12222384
60371591	60371614	18	+	28162770	OCIAML2	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	0.4522023142353789	[23]	[181]	4	hSpCas9	negative selection	12222385
60371689	60371712	18	+	28162770	OCIAML2	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	0.14604153520633334	[14]	[91]	1	hSpCas9	negative selection	12222386
60372313	60372336	18	+	28162770	OCIAML3	viability	GAGAAGTGTGCATCCCACGGTGG	MC4R	ENSG00000166603	-2.356508326597507	[94]	[55]	-9	hSpCas9	negative selection	12391743
60372249	60372272	18	-	28162770	OCIAML3	viability	GCCAGTGAGTCCCTTGGAAAAGG	MC4R	ENSG00000166603	0.34587136723826595	[97]	[375]	3	hSpCas9	negative selection	12391744
60371644	60371667	18	+	28162770	OCIAML3	viability	GGATGGCACCAGTGCCGGGGAGG	MC4R	ENSG00000166603	-0.40136256238176704	[27]	[63]	-3	hSpCas9	negative selection	12391745
60372327	60372350	18	-	28162770	OCIAML3	viability	ATGGTGAACTCCACCCACCGTGG	MC4R	ENSG00000166603	-1.2247738306584441	[47]	[61]	-7	hSpCas9	negative selection	12391746
60371367	60371390	18	+	28162770	OCIAML3	viability	AAGTCACAAAGGCCTCCCAGGGG	MC4R	ENSG00000166603	-0.8681826037631575	[25]	[42]	-6	hSpCas9	negative selection	12391747
60372277	60372300	18	+	28162770	OCIAML3	viability	TGTGCAGTCTGTAACTGCTGCGG	MC4R	ENSG00000166603	0.8350839495122298	[165]	[893]	7	hSpCas9	negative selection	12391748
60372234	60372257	18	-	28162770	OCIAML3	viability	GGAAAAGGCTACTCTGATGGAGG	MC4R	ENSG00000166603	0.6669524372717721	[86]	[416]	6	hSpCas9	negative selection	12391749
60371914	60371937	18	-	28162770	OCIAML3	viability	CAGCCTGCTTTCAATTGCAGTGG	MC4R	ENSG00000166603	0.4503864790342904	[119]	[494]	4	hSpCas9	negative selection	12391750
60371591	60371614	18	+	28162770	OCIAML3	viability	GACGCCAATCAGGATGGTCAAGG	MC4R	ENSG00000166603	1.3388781638173	[43]	[335]	9	hSpCas9	negative selection	12391751
60371689	60371712	18	+	28162770	OCIAML3	viability	GCCTGGCCATCAGGAACATGTGG	MC4R	ENSG00000166603	-1.222038862937205	[16]	[21]	-7	hSpCas9	negative selection	12391752