Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:84465
• Symbol:MEGF11
• Description:multiple EGF like domains 11

DataSource: http://genomecrispr.dkfz.de/#!/results/MEGF11

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
65982321	65982344	CHR_HSCHR15_2_CTG8	+	26472758	Jiyoye	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000277848	-0.1863491327187068	[168]	[111]	-1	hSpCas9	negative selection	98444
65982321	65982344	15	+	26472758	Jiyoye	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	-0.1863491327187068	[168]	[111]	-1	hSpCas9	negative selection	98445
65916838	65916861	15	+	26472758	Jiyoye	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	0.0002657631104299035	[117]	[88]	0	hSpCas9	negative selection	98446
65916838	65916861	CHR_HSCHR15_2_CTG8	+	26472758	Jiyoye	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000277848	0.0002657631104299035	[117]	[88]	0	hSpCas9	negative selection	98447
66119135	66119158	15	-	26472758	Jiyoye	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.7135066213422172	[278]	[344]	5	hSpCas9	negative selection	98448
66131272	66131295	CHR_HSCHR15_2_CTG8	-	26472758	Jiyoye	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000277848	0.7135066213422172	[278]	[344]	5	hSpCas9	negative selection	98449
65982370	65982393	CHR_HSCHR15_2_CTG8	+	26472758	Jiyoye	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000277848	1.0376525414793982	[103]	[160]	6	hSpCas9	negative selection	98450
65982370	65982393	15	+	26472758	Jiyoye	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	1.0376525414793982	[103]	[160]	6	hSpCas9	negative selection	98451
65982332	65982355	CHR_HSCHR15_2_CTG8	-	26472758	Jiyoye	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000277848	1.3660701781762001	[88]	[172]	7	hSpCas9	negative selection	98452
65982332	65982355	15	-	26472758	Jiyoye	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	1.3660701781762001	[88]	[172]	7	hSpCas9	negative selection	98453
65964966	65964989	CHR_HSCHR15_2_CTG8	-	26472758	Jiyoye	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000277848	0.5684562885389342	[92]	[103]	4	hSpCas9	negative selection	98454
65964966	65964989	15	-	26472758	Jiyoye	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	0.5684562885389342	[92]	[103]	4	hSpCas9	negative selection	98455
65957648	65957671	CHR_HSCHR15_2_CTG8	+	26472758	Jiyoye	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000277848	6.655102894949459	[0]	[75]	9	hSpCas9	negative selection	98456
65957648	65957671	15	+	26472758	Jiyoye	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	6.655102894949459	[0]	[75]	9	hSpCas9	negative selection	98457
65957573	65957596	CHR_HSCHR15_2_CTG8	-	26472758	Jiyoye	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000277848	-0.11249565896356362	[161]	[112]	-1	hSpCas9	negative selection	98458
65957573	65957596	15	-	26472758	Jiyoye	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	-0.11249565896356362	[161]	[112]	-1	hSpCas9	negative selection	98459
65922444	65922467	CHR_HSCHR15_2_CTG8	+	26472758	Jiyoye	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000277848	0.7941985046151205	[64]	[84]	5	hSpCas9	negative selection	98460
65922444	65922467	15	+	26472758	Jiyoye	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	0.7941985046151205	[64]	[84]	5	hSpCas9	negative selection	98461
65922350	65922373	15	+	26472758	Jiyoye	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	0.6511009643919627	[37]	[44]	5	hSpCas9	negative selection	98462
65922350	65922373	CHR_HSCHR15_2_CTG8	+	26472758	Jiyoye	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000277848	0.6511009643919627	[37]	[44]	5	hSpCas9	negative selection	98463
65982321	65982344	CHR_HSCHR15_2_CTG8	+	26472758	KBM7	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000277848	-0.20243715589097344	[549,310]	[175,167]	-2	hSpCas9	negative selection	289562
65982321	65982344	15	+	26472758	KBM7	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	-0.20243715589097344	[549,310]	[175,167]	-2	hSpCas9	negative selection	289563
65916838	65916861	15	+	26472758	KBM7	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	0.042267237986821984	[564,359]	[154,277]	0	hSpCas9	negative selection	289564
65916838	65916861	CHR_HSCHR15_2_CTG8	+	26472758	KBM7	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000277848	0.042267237986821984	[564,359]	[154,277]	0	hSpCas9	negative selection	289565
66119135	66119158	15	-	26472758	KBM7	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.15191951285197813	[1331,725]	[363,666]	1	hSpCas9	negative selection	289566
66131272	66131295	CHR_HSCHR15_2_CTG8	-	26472758	KBM7	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000277848	0.15191951285197813	[1331,725]	[363,666]	1	hSpCas9	negative selection	289567
65982370	65982393	CHR_HSCHR15_2_CTG8	+	26472758	KBM7	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000277848	-0.3926362920308982	[554,340]	[207,111]	-4	hSpCas9	negative selection	289568
65982370	65982393	15	+	26472758	KBM7	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	-0.3926362920308982	[554,340]	[207,111]	-4	hSpCas9	negative selection	289569
65982332	65982355	CHR_HSCHR15_2_CTG8	-	26472758	KBM7	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000277848	-0.8032173139515945	[633,396]	[120,149]	-6	hSpCas9	negative selection	289570
65982332	65982355	15	-	26472758	KBM7	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	-0.8032173139515945	[633,396]	[120,149]	-6	hSpCas9	negative selection	289571
65964966	65964989	CHR_HSCHR15_2_CTG8	-	26472758	KBM7	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000277848	-0.10420209992848184	[268,168]	[102,85]	-1	hSpCas9	negative selection	289572
65964966	65964989	15	-	26472758	KBM7	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	-0.10420209992848184	[268,168]	[102,85]	-1	hSpCas9	negative selection	289573
65957648	65957671	CHR_HSCHR15_2_CTG8	+	26472758	KBM7	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000277848	-0.7452332224023768	[296,372]	[132,61]	-6	hSpCas9	negative selection	289574
65957648	65957671	15	+	26472758	KBM7	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	-0.7452332224023768	[296,372]	[132,61]	-6	hSpCas9	negative selection	289575
65957573	65957596	CHR_HSCHR15_2_CTG8	-	26472758	KBM7	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000277848	-0.41183830111089764	[419,562]	[183,170]	-4	hSpCas9	negative selection	289576
65957573	65957596	15	-	26472758	KBM7	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	-0.41183830111089764	[419,562]	[183,170]	-4	hSpCas9	negative selection	289577
65922444	65922467	CHR_HSCHR15_2_CTG8	+	26472758	KBM7	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000277848	-0.06863394121495009	[338,404]	[100,229]	0	hSpCas9	negative selection	289578
65922444	65922467	15	+	26472758	KBM7	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	-0.06863394121495009	[338,404]	[100,229]	0	hSpCas9	negative selection	289579
65922350	65922373	15	+	26472758	KBM7	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	0.08284202180142586	[214,103]	[114,42]	0	hSpCas9	negative selection	289580
65922350	65922373	CHR_HSCHR15_2_CTG8	+	26472758	KBM7	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000277848	0.08284202180142586	[214,103]	[114,42]	0	hSpCas9	negative selection	289581
65982321	65982344	CHR_HSCHR15_2_CTG8	+	26472758	Raji	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000277848	0.26235819534994037	[193]	[53]	2	hSpCas9	negative selection	480680
65982321	65982344	15	+	26472758	Raji	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	0.26235819534994037	[193]	[53]	2	hSpCas9	negative selection	480681
65916838	65916861	15	+	26472758	Raji	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	0.16605944270120726	[264]	[68]	1	hSpCas9	negative selection	480682
65916838	65916861	CHR_HSCHR15_2_CTG8	+	26472758	Raji	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000277848	0.16605944270120726	[264]	[68]	1	hSpCas9	negative selection	480683
66119135	66119158	15	-	26472758	Raji	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.8838952575158786	[438]	[187]	7	hSpCas9	negative selection	480684
66131272	66131295	CHR_HSCHR15_2_CTG8	-	26472758	Raji	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000277848	0.8838952575158786	[438]	[187]	7	hSpCas9	negative selection	480685
65982370	65982393	CHR_HSCHR15_2_CTG8	+	26472758	Raji	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000277848	1.3955089221702237	[189]	[115]	9	hSpCas9	negative selection	480686
65982370	65982393	15	+	26472758	Raji	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	1.3955089221702237	[189]	[115]	9	hSpCas9	negative selection	480687
65982332	65982355	CHR_HSCHR15_2_CTG8	-	26472758	Raji	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000277848	-0.49165415055927963	[205]	[33]	-4	hSpCas9	negative selection	480688
65982332	65982355	15	-	26472758	Raji	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	-0.49165415055927963	[205]	[33]	-4	hSpCas9	negative selection	480689
65964966	65964989	CHR_HSCHR15_2_CTG8	-	26472758	Raji	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000277848	-0.08165028901641747	[113]	[24]	0	hSpCas9	negative selection	480690
65964966	65964989	15	-	26472758	Raji	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	-0.08165028901641747	[113]	[24]	0	hSpCas9	negative selection	480691
65957648	65957671	CHR_HSCHR15_2_CTG8	+	26472758	Raji	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000277848	-0.04378053796005127	[190]	[42]	0	hSpCas9	negative selection	480692
65957648	65957671	15	+	26472758	Raji	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	-0.04378053796005127	[190]	[42]	0	hSpCas9	negative selection	480693
65957573	65957596	CHR_HSCHR15_2_CTG8	-	26472758	Raji	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000277848	0.07713724850547915	[240]	[58]	0	hSpCas9	negative selection	480694
65957573	65957596	15	-	26472758	Raji	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	0.07713724850547915	[240]	[58]	0	hSpCas9	negative selection	480695
65922444	65922467	CHR_HSCHR15_2_CTG8	+	26472758	Raji	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000277848	0.5760020748572873	[184]	[63]	5	hSpCas9	negative selection	480696
65922444	65922467	15	+	26472758	Raji	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	0.5760020748572873	[184]	[63]	5	hSpCas9	negative selection	480697
65922350	65922373	15	+	26472758	Raji	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	-1.132930793960111	[188]	[19]	-7	hSpCas9	negative selection	480698
65922350	65922373	CHR_HSCHR15_2_CTG8	+	26472758	Raji	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000277848	-1.132930793960111	[188]	[19]	-7	hSpCas9	negative selection	480699
65982321	65982344	CHR_HSCHR15_2_CTG8	+	26472758	K562	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000277848	-0.08588903283688865	[258]	[205]	0	hSpCas9	negative selection	671798
65982321	65982344	15	+	26472758	K562	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	-0.08588903283688865	[258]	[205]	0	hSpCas9	negative selection	671799
65916838	65916861	15	+	26472758	K562	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	-0.7398139564752366	[272]	[137]	-4	hSpCas9	negative selection	671800
65916838	65916861	CHR_HSCHR15_2_CTG8	+	26472758	K562	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000277848	-0.7398139564752366	[272]	[137]	-4	hSpCas9	negative selection	671801
66119135	66119158	15	-	26472758	K562	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.7602192038802074	[704]	[1007]	6	hSpCas9	negative selection	671802
66131272	66131295	CHR_HSCHR15_2_CTG8	-	26472758	K562	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000277848	0.7602192038802074	[704]	[1007]	6	hSpCas9	negative selection	671803
65982370	65982393	CHR_HSCHR15_2_CTG8	+	26472758	K562	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000277848	0.34374665479308564	[462]	[495]	2	hSpCas9	negative selection	671804
65982370	65982393	15	+	26472758	K562	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	0.34374665479308564	[462]	[495]	2	hSpCas9	negative selection	671805
65982332	65982355	CHR_HSCHR15_2_CTG8	-	26472758	K562	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000277848	0.48257846486121136	[506]	[597]	4	hSpCas9	negative selection	671806
65982332	65982355	15	-	26472758	K562	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	0.48257846486121136	[506]	[597]	4	hSpCas9	negative selection	671807
65964966	65964989	CHR_HSCHR15_2_CTG8	-	26472758	K562	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000277848	1.0020578900974029	[193]	[327]	8	hSpCas9	negative selection	671808
65964966	65964989	15	-	26472758	K562	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	1.0020578900974029	[193]	[327]	8	hSpCas9	negative selection	671809
65957648	65957671	CHR_HSCHR15_2_CTG8	+	26472758	K562	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000277848	0.541076785571593	[310]	[381]	4	hSpCas9	negative selection	671810
65957648	65957671	15	+	26472758	K562	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	0.541076785571593	[310]	[381]	4	hSpCas9	negative selection	671811
65957573	65957596	CHR_HSCHR15_2_CTG8	-	26472758	K562	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000277848	0.6684226637681507	[400]	[537]	5	hSpCas9	negative selection	671812
65957573	65957596	15	-	26472758	K562	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	0.6684226637681507	[400]	[537]	5	hSpCas9	negative selection	671813
65922444	65922467	CHR_HSCHR15_2_CTG8	+	26472758	K562	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000277848	0.8835369984345085	[243]	[379]	7	hSpCas9	negative selection	671814
65922444	65922467	15	+	26472758	K562	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	0.8835369984345085	[243]	[379]	7	hSpCas9	negative selection	671815
65922350	65922373	15	+	26472758	K562	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	0.3264120998637545	[170]	[180]	2	hSpCas9	negative selection	671816
65922350	65922373	CHR_HSCHR15_2_CTG8	+	26472758	K562	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000277848	0.3264120998637545	[170]	[180]	2	hSpCas9	negative selection	671817
65980767	65980790	15	+	26627737	DLD1	viability	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	-0.10311633600858555	[589]	[105,157,239]	-1	hSpCas9	negative selection	791404
65982367	65982390	15	+	26627737	DLD1	viability	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.08933208060282127	[1039]	[337,272,412]	0	hSpCas9	negative selection	791405
66094471	66094494	15	+	26627737	DLD1	viability	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.5450884596189414	[1936]	[430,530,304]	-5	hSpCas9	negative selection	791406
66119157	66119180	15	-	26627737	DLD1	viability	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	0.3887624990161056	[394]	[114,290,94]	4	hSpCas9	negative selection	791407
66123898	66123921	15	-	26627737	DLD1	viability	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	-0.06501049021559013	[252]	[75,58,88]	0	hSpCas9	negative selection	791408
66128295	66128318	15	+	26627737	DLD1	viability	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.2553811712788121	[1418]	[358,428,334]	-3	hSpCas9	negative selection	791409
65980767	65980790	15	+	26627737	GBM cells	viability after 5 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.667098199662612	[127]	[90,126]	8	hSpCas9	negative selection	873719
65982367	65982390	15	+	26627737	GBM cells	viability after 5 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.2644155174653168	[436]	[341,220]	4	hSpCas9	negative selection	873720
66094471	66094494	15	+	26627737	GBM cells	viability after 5 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.12285394019655005	[600]	[361,229]	-2	hSpCas9	negative selection	873721
66119157	66119180	15	-	26627737	GBM cells	viability after 5 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.08025262169714875	[274]	[127,150]	-1	hSpCas9	negative selection	873722
66123898	66123921	15	-	26627737	GBM cells	viability after 5 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	-0.361737879637114	[120]	[46,53]	-5	hSpCas9	negative selection	873723
66128295	66128318	15	+	26627737	GBM cells	viability after 5 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.10734511558599658	[461]	[262,196]	-2	hSpCas9	negative selection	873724
65980767	65980790	15	+	26627737	GBM cells	viability after 13 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.6305919814528205	[127]	[117,98]	7	hSpCas9	negative selection	956034
65982367	65982390	15	+	26627737	GBM cells	viability after 13 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.5288383332998464	[436]	[458,246]	6	hSpCas9	negative selection	956035
66094471	66094494	15	+	26627737	GBM cells	viability after 13 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.32617915436423783	[600]	[333,199]	-4	hSpCas9	negative selection	956036
66119157	66119180	15	-	26627737	GBM cells	viability after 13 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	0.02142902871354327	[274]	[210,102]	0	hSpCas9	negative selection	956037
66123898	66123921	15	-	26627737	GBM cells	viability after 13 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	-0.2619730540949736	[120]	[35,69]	-3	hSpCas9	negative selection	956038
66128295	66128318	15	+	26627737	GBM cells	viability after 13 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	0.04695756666859785	[461]	[253,262]	0	hSpCas9	negative selection	956039
65980767	65980790	15	+	26627737	GBM cells	viability after 21 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.35740690543675446	[127]	[86,90]	3	hSpCas9	negative selection	1038349
65982367	65982390	15	+	26627737	GBM cells	viability after 21 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.21819725990722583	[436]	[271,279]	2	hSpCas9	negative selection	1038350
66094471	66094494	15	+	26627737	GBM cells	viability after 21 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.9715132412911944	[600]	[177,155]	-7	hSpCas9	negative selection	1038351
66119157	66119180	15	-	26627737	GBM cells	viability after 21 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.20612244306152577	[274]	[140,118]	-2	hSpCas9	negative selection	1038352
66123898	66123921	15	-	26627737	GBM cells	viability after 21 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	-0.3119197977983399	[120]	[53,51]	-3	hSpCas9	negative selection	1038353
66128295	66128318	15	+	26627737	GBM cells	viability after 21 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.24578973082653088	[461]	[230,193]	-2	hSpCas9	negative selection	1038354
65980767	65980790	15	+	26627737	RPE1	viability after 9 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	-0.8054914714589885	[1354]	[257,222]	-5	hSpCas9	negative selection	1120664
65982367	65982390	15	+	26627737	RPE1	viability after 9 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.7945040207442661	[1335]	[335,1227]	5	hSpCas9	negative selection	1120665
66094471	66094494	15	+	26627737	RPE1	viability after 9 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.5377600681850393	[1752]	[212,590]	-4	hSpCas9	negative selection	1120666
66119157	66119180	15	-	26627737	RPE1	viability after 9 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.7891754907192611	[1405]	[207,314]	-5	hSpCas9	negative selection	1120667
66123898	66123921	15	-	26627737	RPE1	viability after 9 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.8131968303074902	[246]	[41,256]	5	hSpCas9	negative selection	1120668
66128295	66128318	15	+	26627737	RPE1	viability after 9 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-1.1191456729177363	[2952]	[477,357]	-7	hSpCas9	negative selection	1120669
65980767	65980790	15	+	26627737	RPE1	viability after 12 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	-0.4314554921159052	[1354]	[301,235]	-3	hSpCas9	negative selection	1202979
65982367	65982390	15	+	26627737	RPE1	viability after 12 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.5261883828855304	[1335]	[377,663]	3	hSpCas9	negative selection	1202980
66094471	66094494	15	+	26627737	RPE1	viability after 12 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.11905126697961488	[1752]	[306,727]	0	hSpCas9	negative selection	1202981
66119157	66119180	15	-	26627737	RPE1	viability after 12 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.32109145356074653	[1405]	[314,288]	-2	hSpCas9	negative selection	1202982
66123898	66123921	15	-	26627737	RPE1	viability after 12 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.7587747602894626	[246]	[121,101]	5	hSpCas9	negative selection	1202983
66128295	66128318	15	+	26627737	RPE1	viability after 12 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-1.1568156825285105	[2952]	[417,289]	-7	hSpCas9	negative selection	1202984
65980767	65980790	15	+	26627737	RPE1	viability after 15 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	-0.42477555433787506	[1354]	[451,124]	-3	hSpCas9	negative selection	1285294
65982367	65982390	15	+	26627737	RPE1	viability after 15 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.317232768627122	[1335]	[224,707]	2	hSpCas9	negative selection	1285295
66094471	66094494	15	+	26627737	RPE1	viability after 15 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.5832559505885568	[1752]	[998,495]	3	hSpCas9	negative selection	1285296
66119157	66119180	15	-	26627737	RPE1	viability after 15 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.06396514653210816	[1405]	[437,324]	0	hSpCas9	negative selection	1285297
66123898	66123921	15	-	26627737	RPE1	viability after 15 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	1.4678498050997781	[246]	[149,234]	7	hSpCas9	negative selection	1285298
66128295	66128318	15	+	26627737	RPE1	viability after 15 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-1.493976244183468	[2952]	[404,191]	-7	hSpCas9	negative selection	1285299
65980767	65980790	15	+	26627737	RPE1	viability after 18 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	-0.2943228733485185	[1354]	[361,229]	-2	hSpCas9	negative selection	1367609
65982367	65982390	15	+	26627737	RPE1	viability after 18 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.3727594684490704	[1335]	[301,642]	2	hSpCas9	negative selection	1367610
66094471	66094494	15	+	26627737	RPE1	viability after 18 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.4394540286973312	[1752]	[394,904]	2	hSpCas9	negative selection	1367611
66119157	66119180	15	-	26627737	RPE1	viability after 18 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.5485830618177139	[1405]	[256,261]	-3	hSpCas9	negative selection	1367612
66123898	66123921	15	-	26627737	RPE1	viability after 18 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.9629849377436632	[246]	[98,162]	6	hSpCas9	negative selection	1367613
66128295	66128318	15	+	26627737	RPE1	viability after 18 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-1.2812249091407129	[2952]	[382,268]	-7	hSpCas9	negative selection	1367614
65980767	65980790	15	+	26627737	HeLa	viability after 8 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.4365589735895073	[245]	[265,164,37]	4	hSpCas9	negative selection	1449924
65982367	65982390	15	+	26627737	HeLa	viability after 8 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.3075477988717312	[772]	[723,167,423]	3	hSpCas9	negative selection	1449925
66094471	66094494	15	+	26627737	HeLa	viability after 8 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.34682636863703054	[769]	[360,174,274]	-3	hSpCas9	negative selection	1449926
66119157	66119180	15	-	26627737	HeLa	viability after 8 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	1.1878873894756383	[167]	[208,207,96]	8	hSpCas9	negative selection	1449927
66123898	66123921	15	-	26627737	HeLa	viability after 8 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.3609274309763584	[96]	[88,22,57]	3	hSpCas9	negative selection	1449928
66128295	66128318	15	+	26627737	HeLa	viability after 8 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-2.1988093525632353	[991]	[86,76,114]	-9	hSpCas9	negative selection	1449929
65980767	65980790	15	+	26627737	HeLa	viability after 12 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.5069928559215413	[245]	[147,205,72]	4	hSpCas9	negative selection	1532239
65982367	65982390	15	+	26627737	HeLa	viability after 12 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.015813541690444466	[772]	[200,335,426]	0	hSpCas9	negative selection	1532240
66094471	66094494	15	+	26627737	HeLa	viability after 12 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.24550616573718798	[769]	[185,444,487]	2	hSpCas9	negative selection	1532241
66119157	66119180	15	-	26627737	HeLa	viability after 12 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	1.2409183021240642	[167]	[241,206,40]	8	hSpCas9	negative selection	1532242
66123898	66123921	15	-	26627737	HeLa	viability after 12 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.3936064143175977	[96]	[20,90,40]	3	hSpCas9	negative selection	1532243
66128295	66128318	15	+	26627737	HeLa	viability after 12 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.29653997624346995	[991]	[483,151,388]	-3	hSpCas9	negative selection	1532244
65980767	65980790	15	+	26627737	HeLa	viability after 15 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.7993936109866864	[245]	[155,157,211]	6	hSpCas9	negative selection	1614554
65982367	65982390	15	+	26627737	HeLa	viability after 15 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.37760287565854234	[772]	[379,315,540]	3	hSpCas9	negative selection	1614555
66094471	66094494	15	+	26627737	HeLa	viability after 15 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.16142461080630688	[769]	[304,279,476]	1	hSpCas9	negative selection	1614556
66119157	66119180	15	-	26627737	HeLa	viability after 15 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.017230205864127823	[167]	[62,93,43]	0	hSpCas9	negative selection	1614557
66123898	66123921	15	-	26627737	HeLa	viability after 15 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.7822750111613739	[96]	[85,91,21]	6	hSpCas9	negative selection	1614558
66128295	66128318	15	+	26627737	HeLa	viability after 15 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.34163241516683684	[991]	[481,152,318]	-3	hSpCas9	negative selection	1614559
65980767	65980790	15	+	26627737	HeLa	viability after 18 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.8039253380768131	[245]	[103,132,211]	6	hSpCas9	negative selection	1696869
65982367	65982390	15	+	26627737	HeLa	viability after 18 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.4270117462034835	[772]	[275,269,540]	3	hSpCas9	negative selection	1696870
66094471	66094494	15	+	26627737	HeLa	viability after 18 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.19007348757384945	[769]	[210,240,476]	1	hSpCas9	negative selection	1696871
66119157	66119180	15	-	26627737	HeLa	viability after 18 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	0.08508677885846283	[167]	[46,83,43]	0	hSpCas9	negative selection	1696872
66123898	66123921	15	-	26627737	HeLa	viability after 18 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.7238168161796845	[96]	[54,72,21]	5	hSpCas9	negative selection	1696873
66128295	66128318	15	+	26627737	HeLa	viability after 18 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.37877670631856875	[991]	[312,119,318]	-3	hSpCas9	negative selection	1696874
65980767	65980790	15	+	26627737	HCT116	viability after 6 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	2.3325952235539242	[212]	[430,23]	9	hSpCas9	negative selection	1779184
65982367	65982390	15	+	26627737	HCT116	viability after 6 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	-0.4419631937692641	[1451]	[236,129]	-3	hSpCas9	negative selection	1779185
66094471	66094494	15	+	26627737	HCT116	viability after 6 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.28397010130277534	[2047]	[527,316]	1	hSpCas9	negative selection	1779186
66119157	66119180	15	-	26627737	HCT116	viability after 6 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	1.2859888760454705	[378]	[7,220]	7	hSpCas9	negative selection	1779187
66123898	66123921	15	-	26627737	HCT116	viability after 6 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	-0.876428390993576	[349]	[67,8]	-5	hSpCas9	negative selection	1779188
66128295	66128318	15	+	26627737	HCT116	viability after 6 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	0.028767923277613905	[1308]	[236,194]	0	hSpCas9	negative selection	1779189
65980767	65980790	15	+	26627737	HCT116	viability after 8 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.6106859398110557	[153]	[146,108,132]	6	hSpCas9	negative selection	1861499
65982367	65982390	15	+	26627737	HCT116	viability after 8 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	-0.3025542806223167	[761]	[273,392,352]	-4	hSpCas9	negative selection	1861500
66094471	66094494	15	+	26627737	HCT116	viability after 8 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.3380419286971874	[771]	[196,381,426]	-4	hSpCas9	negative selection	1861501
66119157	66119180	15	-	26627737	HCT116	viability after 8 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.18797236089101244	[372]	[137,261,140]	-2	hSpCas9	negative selection	1861502
66123898	66123921	15	-	26627737	HCT116	viability after 8 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.25020622176104035	[102]	[32,109,58]	3	hSpCas9	negative selection	1861503
66128295	66128318	15	+	26627737	HCT116	viability after 8 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.21704605276967692	[611]	[327,330,212]	-2	hSpCas9	negative selection	1861504
65980767	65980790	15	+	26627737	HCT116	viability after 9 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	1.7720007962200013	[212]	[210,180]	9	hSpCas9	negative selection	1943814
65982367	65982390	15	+	26627737	HCT116	viability after 9 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	-0.44771651079053776	[1451]	[233,323]	-3	hSpCas9	negative selection	1943815
66094471	66094494	15	+	26627737	HCT116	viability after 9 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.11736021683295528	[2047]	[824,409]	0	hSpCas9	negative selection	1943816
66119157	66119180	15	-	26627737	HCT116	viability after 9 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	0.5810369773187885	[378]	[161,142]	4	hSpCas9	negative selection	1943817
66123898	66123921	15	-	26627737	HCT116	viability after 9 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	-2.4967161155399316	[349]	[15,16]	-9	hSpCas9	negative selection	1943818
66128295	66128318	15	+	26627737	HCT116	viability after 9 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.7927863911988182	[1308]	[246,165]	-5	hSpCas9	negative selection	1943819
65980767	65980790	15	+	26627737	HCT116	viability after 12 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	1.10258821845118	[153]	[194,193,130]	8	hSpCas9	negative selection	2026129
65982367	65982390	15	+	26627737	HCT116	viability after 12 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.22691491735685787	[761]	[395,494,521]	2	hSpCas9	negative selection	2026130
66094471	66094494	15	+	26627737	HCT116	viability after 12 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.26931852613311613	[771]	[339,230,435]	-3	hSpCas9	negative selection	2026131
66119157	66119180	15	-	26627737	HCT116	viability after 12 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.737603310745601	[372]	[44,238,77]	-7	hSpCas9	negative selection	2026132
66123898	66123921	15	-	26627737	HCT116	viability after 12 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.36480026161681134	[102]	[62,40,104]	3	hSpCas9	negative selection	2026133
66128295	66128318	15	+	26627737	HCT116	viability after 12 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.5092943281451082	[611]	[201,143,331]	-5	hSpCas9	negative selection	2026134
65980767	65980790	15	+	26627737	HCT116	viability after 15 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.9163512954408424	[153]	[294,108,112]	7	hSpCas9	negative selection	2108444
65982367	65982390	15	+	26627737	HCT116	viability after 15 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	-0.08446115281265776	[761]	[537,349,365]	-1	hSpCas9	negative selection	2108445
66094471	66094494	15	+	26627737	HCT116	viability after 15 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.9030692396159417	[771]	[178,272,251]	-7	hSpCas9	negative selection	2108446
66119157	66119180	15	-	26627737	HCT116	viability after 15 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.6271158044032619	[372]	[132,193,88]	-6	hSpCas9	negative selection	2108447
66123898	66123921	15	-	26627737	HCT116	viability after 15 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.6274612150439576	[102]	[59,91,117]	6	hSpCas9	negative selection	2108448
66128295	66128318	15	+	26627737	HCT116	viability after 15 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.46423287776870725	[611]	[258,183,320]	-5	hSpCas9	negative selection	2108449
65980767	65980790	15	+	26627737	HCT116	viability after 18 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	1.2504851402770585	[153]	[231,140,159]	8	hSpCas9	negative selection	2190759
65982367	65982390	15	+	26627737	HCT116	viability after 18 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.002145061544677862	[761]	[225,485,387]	0	hSpCas9	negative selection	2190760
66094471	66094494	15	+	26627737	HCT116	viability after 18 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.07608865481583482	[771]	[392,421,361]	0	hSpCas9	negative selection	2190761
66119157	66119180	15	-	26627737	HCT116	viability after 18 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.354076831688997	[372]	[112,188,116]	-3	hSpCas9	negative selection	2190762
66123898	66123921	15	-	26627737	HCT116	viability after 18 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.06127918810666744	[102]	[30,67,55]	0	hSpCas9	negative selection	2190763
66128295	66128318	15	+	26627737	HCT116	viability after 18 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.7519720663373606	[611]	[128,143,259]	-6	hSpCas9	negative selection	2190764
66242364	66242387	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCCACTGCACTCCAGCCTAAG	MEGF11	ENSG00000157890	-0.4511660430985071	[55,91]	[10,11]	-2	dCas9-VP64	positive selection	2390464
66254501	66254524	CHR_HSCHR15_2_CTG8	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCCACTGCACTCCAGCCTAAG	MEGF11	ENSG00000277848	-0.4511660430985071	[55,91]	[10,11]	-2	dCas9-VP64	positive selection	2390465
66197697	66197720	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACTGCACCTAG	MEGF11	ENSG00000157890	0.9550246130222104	[38,14]	[18,2]	4	dCas9-VP64	positive selection	2414041
66209834	66209857	CHR_HSCHR15_2_CTG8	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACTGCACCTAG	MEGF11	ENSG00000277848	0.9550246130222104	[38,14]	[18,2]	4	dCas9-VP64	positive selection	2414042
66206879	66206902	CHR_HSCHR15_2_CTG8	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGTGGTGATTTCTGAGATTTGGG	MEGF11	ENSG00000277848	1.0469029585009717	[317,416]	[49,294]	4	dCas9-VP64	positive selection	2442114
66194742	66194765	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGTGGTGATTTCTGAGATTTGGG	MEGF11	ENSG00000157890	1.0469029585009717	[317,416]	[49,294]	4	dCas9-VP64	positive selection	2442115
66242364	66242387	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCCACTGCACTCCAGCCTAAG	MEGF11	ENSG00000157890	-0.10831419915270625	[89,129]	[31,33]	-1	dCas9-VP64	positive selection	2485719
66254501	66254524	CHR_HSCHR15_2_CTG8	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCCACTGCACTCCAGCCTAAG	MEGF11	ENSG00000277848	-0.10831419915270625	[89,129]	[31,33]	-1	dCas9-VP64	positive selection	2485720
66197697	66197720	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACTGCACCTAG	MEGF11	ENSG00000157890	-0.28279012529460834	[51,110]	[30,11]	-3	dCas9-VP64	positive selection	2509296
66209834	66209857	CHR_HSCHR15_2_CTG8	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACTGCACCTAG	MEGF11	ENSG00000277848	-0.28279012529460834	[51,110]	[30,11]	-3	dCas9-VP64	positive selection	2509297
66206879	66206902	CHR_HSCHR15_2_CTG8	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGTGGTGATTTCTGAGATTTGGG	MEGF11	ENSG00000277848	0.9661199072074318	[327,324]	[329,93]	6	dCas9-VP64	positive selection	2537369
66194742	66194765	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGTGGTGATTTCTGAGATTTGGG	MEGF11	ENSG00000157890	0.9661199072074318	[327,324]	[329,93]	6	dCas9-VP64	positive selection	2537370
65970561	65970584	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCATGTATCCAGCTGTACAGTGG	MEGF11	ENSG00000157890	0.3757254202666808	[4,4]	[4,5]	7	hSpCas9	positive selection	3001921
65982332	65982355	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	0.1776826148934326	[3,2]	[1,3]	4	hSpCas9	positive selection	3001922
65965110	65965133	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCTCCCACAGGTGCCAAGAGG	MEGF11	ENSG00000157890	-0.8352776970685626	[2,3]	[2,0]	-8	hSpCas9	positive selection	3001923
65964913	65964936	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGTGTTGTCAGCGTCACAGGGG	MEGF11	ENSG00000157890	-0.5247578012744518	[2,3]	[2,0]	-6	hSpCas9	positive selection	3001924
65970561	65970584	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCATGTATCCAGCTGTACAGTGG	MEGF11	ENSG00000157890	-0.08533793843242485	[4,4]	[4,1]	-1	hSpCas9	positive selection	3069779
65982332	65982355	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	-0.5287878220175704	[3,3]	[2,0]	-7	hSpCas9	positive selection	3069780
65965110	65965133	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCTCCCACAGGTGCCAAGAGG	MEGF11	ENSG00000157890	0.308110921246903	[2,2]	[2,2]	5	hSpCas9	positive selection	3069781
65964913	65964936	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGTGTTGTCAGCGTCACAGGGG	MEGF11	ENSG00000157890	0.2993831892456866	[2,2]	[1,2]	5	hSpCas9	positive selection	3069782
66094444	66094467		+	24336571	A375	resistance to PLX after 7 days	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.1980951981250041	[3,2]	[3,3]	6	hSpCas9	positive selection	3127088
66094450	66094473		-	24336571	A375	resistance to PLX after 7 days	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.011240354870950764	[9,7]	[8,7]	0	hSpCas9	positive selection	3127089
66123943	66123966		+	24336571	A375	resistance to PLX after 7 days	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	0.04027062530083825	[4,8]	[5,7]	1	hSpCas9	positive selection	3127090
66094444	66094467		+	24336571	A375	resistance to PLX after 14 days	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	1.2908643260292207	[2,3]	[4,2]	8	hSpCas9	positive selection	3184881
66094450	66094473		-	24336571	A375	resistance to PLX after 14 days	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	-0.14663195454577949	[10,9]	[3,3]	-1	hSpCas9	positive selection	3184882
66123943	66123966		+	24336571	A375	resistance to PLX after 14 days	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	0.8390535788413908	[3,14]	[7,7]	7	hSpCas9	positive selection	3184883
66094444	66094467		+	24336571	A375	viability after 7 days	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.48831583135365175	[4]	[3,2]	-6	hSpCas9	negative selection	3242674
66094450	66094473		-	24336571	A375	viability after 7 days	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.5332821524208533	[5]	[9,7]	7	hSpCas9	negative selection	3242675
66123943	66123966		+	24336571	A375	viability after 7 days	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.42279531013766164	[9]	[4,8]	-6	hSpCas9	negative selection	3242676
66094444	66094467		+	24336571	A375	viability after 14 days	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.46333174500316465	[4]	[2,3]	-5	hSpCas9	negative selection	3300467
66094450	66094473		-	24336571	A375	viability after 14 days	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.832353049664913	[5]	[10,9]	9	hSpCas9	negative selection	3300468
66123943	66123966		+	24336571	A375	viability after 14 days	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	0.08506950153143189	[9]	[3,14]	1	hSpCas9	negative selection	3300469
66094450	66094473	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	3.4499712893882313	[13,13]	[0,0]	9	hSpCas9	positive selection	3378994
66094444	66094467	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	1.2129320920873818	[65,65]	[0,0]	5	hSpCas9	positive selection	3378995
66123981	66124004	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-1.8590177497916331	[554,554]	[0,0]	-9	hSpCas9	positive selection	3378996
65970560	65970583	15	+	26780180	HT29	viability (Avana library 4 designs)	CCATGTATCCAGCTGTACAGTGG	MEGF11	ENSG00000157890	0.283364265452091	[]	[]	1	hSpCas9	negative selection	3439655
65982332	65982355	15	-	26780180	HT29	viability (Avana library 4 designs)	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	2.14116018725249	[]	[]	7	hSpCas9	negative selection	3439656
65965110	65965133	15	-	26780180	HT29	viability (Avana library 4 designs)	GCTCTCCCACAGGTGCCAAGAGG	MEGF11	ENSG00000157890	0.945319692392052	[]	[]	3	hSpCas9	negative selection	3439657
65964912	65964935	15	+	26780180	HT29	viability (Avana library 4 designs)	TGGTGTTGTCAGCGTCACAGGGG	MEGF11	ENSG00000157890	1.27209964455376	[]	[]	5	hSpCas9	negative selection	3439658
65970560	65970583	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCATGTATCCAGCTGTACAGTGG	MEGF11	ENSG00000157890	0.494258055562277	[]	[]	0	hSpCas9	negative selection	3529505
65965110	65965133	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCTCCCACAGGTGCCAAGAGG	MEGF11	ENSG00000157890	3.33227192826993	[]	[]	5	hSpCas9	negative selection	3529506
65982332	65982355	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	4.0101846356547	[]	[]	6	hSpCas9	negative selection	3529507
65964912	65964935	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGTGTTGTCAGCGTCACAGGGG	MEGF11	ENSG00000157890	1.41088904167019	[]	[]	2	hSpCas9	negative selection	3529508
66094444	66094467	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.0783977909361762	[]	[]	0	hSpCas9	negative selection	3529509
65982321	65982344	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	4.88628118628611	[]	[]	8	hSpCas9	negative selection	3529510
65970560	65970583	15	+	26780180	A375	viability (Avana lentiGuide)	CCATGTATCCAGCTGTACAGTGG	MEGF11	ENSG00000157890	-0.706736270410214	[]	[]	-1	hSpCas9	negative selection	3638164
65965110	65965133	15	-	26780180	A375	viability (Avana lentiGuide)	GCTCTCCCACAGGTGCCAAGAGG	MEGF11	ENSG00000157890	0.929852912463672	[]	[]	1	hSpCas9	negative selection	3638165
65982332	65982355	15	-	26780180	A375	viability (Avana lentiGuide)	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	0.813256243363694	[]	[]	1	hSpCas9	negative selection	3638166
65964912	65964935	15	+	26780180	A375	viability (Avana lentiGuide)	TGGTGTTGTCAGCGTCACAGGGG	MEGF11	ENSG00000157890	-3.86198104609929	[]	[]	-6	hSpCas9	negative selection	3638167
66094444	66094467	15	+	26780180	A375	viability (Avana lentiGuide)	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.551502363626368	[]	[]	-1	hSpCas9	negative selection	3638168
65982321	65982344	15	+	26780180	A375	viability (Avana lentiGuide)	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	12.4941857427934	[]	[]	7	hSpCas9	negative selection	3638169
65970560	65970583	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATGTATCCAGCTGTACAGTGG	MEGF11	ENSG00000157890	-0.16131449831283812	[5]	[5,4]	-3	hSpCas9	positive selection	3746823
65965110	65965133	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCTCCCACAGGTGCCAAGAGG	MEGF11	ENSG00000157890	0.05902397259788644	[4]	[4,3]	1	hSpCas9	positive selection	3746824
65982332	65982355	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	0.09534627283854225	[4]	[5,3]	2	hSpCas9	positive selection	3746825
65964912	65964935	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGTGTTGTCAGCGTCACAGGGG	MEGF11	ENSG00000157890	0.2449599887677259	[4]	[5,4]	7	hSpCas9	positive selection	3746826
66094444	66094467	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.22277374425509783	[4]	[3,3]	-4	hSpCas9	positive selection	3746827
65982321	65982344	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	-0.030679151481631917	[3]	[4,2]	0	hSpCas9	positive selection	3746828
65970560	65970583	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATGTATCCAGCTGTACAGTGG	MEGF11	ENSG00000157890	0.1911306079928506	[6]	[6,5]	5	hSpCas9	positive selection	3855430
65965110	65965133	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCTCCCACAGGTGCCAAGAGG	MEGF11	ENSG00000157890	-0.16060308464594536	[4]	[2,3]	-2	hSpCas9	positive selection	3855431
65982332	65982355	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	0.1353511211444477	[4]	[3,4]	3	hSpCas9	positive selection	3855432
65964912	65964935	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGTGTTGTCAGCGTCACAGGGG	MEGF11	ENSG00000157890	0.2512479675794166	[4]	[4,5]	6	hSpCas9	positive selection	3855433
66094444	66094467	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.02586509127582519	[4]	[4,3]	0	hSpCas9	positive selection	3855434
65982321	65982344	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	-1.2907544813579916	[3]	[0,1]	-9	hSpCas9	positive selection	3855435
66094444	66094467	15	+	26780180	A375	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.934457609563726	[]	[]	4	hSpCas9	negative selection	3960920
66123981	66124004	15	-	26780180	A375	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.625955356351782	[]	[]	2	hSpCas9	negative selection	3960921
66094450	66094473	15	-	26780180	A375	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.70372349229692	[]	[]	2	hSpCas9	negative selection	3960922
65982417	65982440	15	+	26780180	A375	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	1.52027735228555	[]	[]	8	hSpCas9	negative selection	3960923
65982377	65982400	15	-	26780180	A375	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.462974116894081	[]	[]	1	hSpCas9	negative selection	3960924
66123943	66123966	15	+	26780180	A375	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	1.63823921149361	[]	[]	8	hSpCas9	negative selection	3960925
66094444	66094467	15	+	26780180	HT29	viability (GeCKOv2 library)	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	1.38325984919035	[]	[]	7	hSpCas9	negative selection	4068886
66123981	66124004	15	-	26780180	HT29	viability (GeCKOv2 library)	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.169108272354147	[]	[]	0	hSpCas9	negative selection	4068887
66094450	66094473	15	-	26780180	HT29	viability (GeCKOv2 library)	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.543653626210595	[]	[]	1	hSpCas9	negative selection	4068888
65982417	65982440	15	+	26780180	HT29	viability (GeCKOv2 library)	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	1.37176443223974	[]	[]	7	hSpCas9	negative selection	4068889
65982377	65982400	15	-	26780180	HT29	viability (GeCKOv2 library)	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.108552433650903	[]	[]	0	hSpCas9	negative selection	4068890
66123943	66123966	15	+	26780180	HT29	viability (GeCKOv2 library)	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	1.73046098595089	[]	[]	8	hSpCas9	negative selection	4068891
66094444	66094467	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.1551382669557384	[1]	[0,1]	4	hSpCas9	positive selection	4151400
66094450	66094473	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	-0.09326681954108632	[3]	[1,1]	-2	hSpCas9	positive selection	4151401
66123943	66123966	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	0.36550294822107376	[3]	[2,2]	8	hSpCas9	positive selection	4151402
66094444	66094467	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.040448195211542304	[2]	[0,2,0,0]	0	hSpCas9	positive selection	4215422
66094450	66094473	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	-0.4607858601649441	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4215423
66123943	66123966	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	2.186350327395827	[1]	[1,2,3,4]	9	hSpCas9	positive selection	4215424
65982377	65982400	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.00944380848815396	[1]	[1,0]	0	hSpCas9	positive selection	4282509
65982417	65982440	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.24943911500310878	[2]	[2,1]	-5	hSpCas9	positive selection	4282510
66123943	66123966	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.34745927112873176	[2]	[0,1]	-6	hSpCas9	positive selection	4282511
66094450	66094473	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.05507823992866556	[0]	[0,0]	1	hSpCas9	positive selection	4346767
66094444	66094467	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.20425120748814973	[2]	[1,1]	4	hSpCas9	positive selection	4346768
66123981	66124004	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.15622132575432263	[4]	[4,3]	3	hSpCas9	positive selection	4346769
65957630	65957652	15	+	27760321	OCIAML3	viability	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	-0.2019080807136577	[575,472]	[281,449]	-2	hSpCas9	negative selection	4417696
65982302	65982324	15	-	27760321	OCIAML3	viability	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	0.8565706477937474	[1024,820]	[1144,1500]	8	hSpCas9	negative selection	4417697
66119135	66119157	15	-	27760321	OCIAML3	viability	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.3092152094977403	[961,802]	[687,1064]	3	hSpCas9	negative selection	4417698
66119157	66119179	15	-	27760321	OCIAML3	viability	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.7420205198030956	[306,240]	[138,111]	-6	hSpCas9	negative selection	4417699
66123946	66123968	15	+	27760321	OCIAML3	viability	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	0.9414274480551195	[113,84]	[102,206]	9	hSpCas9	negative selection	4417700
65957630	65957652	15	+	27760321	OCIAML2	viability	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	-0.06790662494938579	[575,472]	[360,457]	-1	hSpCas9	negative selection	4501159
65982302	65982324	15	-	27760321	OCIAML2	viability	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	0.675450126517942	[1024,820]	[930,1520]	8	hSpCas9	negative selection	4501160
66119135	66119157	15	-	27760321	OCIAML2	viability	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.22485514670034412	[961,802]	[659,1055]	3	hSpCas9	negative selection	4501161
66119157	66119179	15	-	27760321	OCIAML2	viability	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-1.3433975936761913	[306,240]	[56,125]	-8	hSpCas9	negative selection	4501162
66123946	66123968	15	+	27760321	OCIAML2	viability	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	-0.7334820134871731	[113,84]	[69,18]	-6	hSpCas9	negative selection	4501163
65957630	65957652	15	+	27760321	MV411	viability	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	-1.4904140275904025	[575,472]	[120,124]	-7	hSpCas9	negative selection	4584622
65982302	65982324	15	-	27760321	MV411	viability	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	1.2282139588388317	[1024,820]	[809,2332]	8	hSpCas9	negative selection	4584623
66119135	66119157	15	-	27760321	MV411	viability	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	-0.03195116499350881	[961,802]	[404,810]	0	hSpCas9	negative selection	4584624
66119157	66119179	15	-	27760321	MV411	viability	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-4.257205378089595	[306,240]	[0,21]	-9	hSpCas9	negative selection	4584625
66123946	66123968	15	+	27760321	MV411	viability	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	-2.080631702950633	[113,84]	[0,36]	-8	hSpCas9	negative selection	4584626
65957630	65957652	15	+	27760321	HL60	viability	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	0.17041694715632077	[575,472]	[458,501]	2	hSpCas9	negative selection	4668085
65982302	65982324	15	-	27760321	HL60	viability	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	0.2866266139852516	[1024,820]	[909,918]	3	hSpCas9	negative selection	4668086
66119135	66119157	15	-	27760321	HL60	viability	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.37107961972943704	[961,802]	[928,927]	4	hSpCas9	negative selection	4668087
66119157	66119179	15	-	27760321	HL60	viability	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.20411603409437507	[306,240]	[209,174]	-2	hSpCas9	negative selection	4668088
66123946	66123968	15	+	27760321	HL60	viability	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	0.13655739956065505	[113,84]	[90,85]	1	hSpCas9	negative selection	4668089
65957630	65957652	15	+	27760321	HT1080	viability	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	0.9563762704703551	[472,368]	[207,453]	5	hSpCas9	negative selection	4751548
65982302	65982324	15	-	27760321	HT1080	viability	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	0.6158010649016201	[820,640]	[377,520]	3	hSpCas9	negative selection	4751549
66119135	66119157	15	-	27760321	HT1080	viability	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.4888774069692975	[802,626]	[488,301]	2	hSpCas9	negative selection	4751550
66119157	66119179	15	-	27760321	HT1080	viability	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-1.0899018348191476	[240,187]	[0,82]	-4	hSpCas9	negative selection	4751551
66123946	66123968	15	+	27760321	HT1080	viability	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	-1.2279214523587876	[84,66]	[0,25]	-5	hSpCas9	negative selection	4751552
65957630	65957652	15	+	27760321	HT29	viability after 7 days	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	0.043869096844787014	[472,368]	[803,402,502]	0	hSpCas9	negative selection	4835011
65982302	65982324	15	-	27760321	HT29	viability after 7 days	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	0.47665588162499106	[820,640]	[1559,1260,1141]	7	hSpCas9	negative selection	4835012
66119135	66119157	15	-	27760321	HT29	viability after 7 days	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.6843301239152876	[802,626]	[1636,1067,1738]	9	hSpCas9	negative selection	4835013
66119157	66119179	15	-	27760321	HT29	viability after 7 days	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.7960700679735413	[240,187]	[123,274,74]	-8	hSpCas9	negative selection	4835014
66123946	66123968	15	+	27760321	HT29	viability after 7 days	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	-0.12657259749205751	[84,66]	[182,44,54]	-2	hSpCas9	negative selection	4835015
65957630	65957652	15	+	27760321	HT29	viability after 25 days	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	0.23777291278759582	[472,368]	[353,590,792]	2	hSpCas9	negative selection	4918474
65982302	65982324	15	-	27760321	HT29	viability after 25 days	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	0.9625091337501801	[820,640]	[1724,1361,1806]	9	hSpCas9	negative selection	4918475
66119135	66119157	15	-	27760321	HT29	viability after 25 days	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.8189049441817239	[802,626]	[1258,1260,1856]	8	hSpCas9	negative selection	4918476
66119157	66119179	15	-	27760321	HT29	viability after 25 days	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.25239172742290494	[240,187]	[199,128,297]	-3	hSpCas9	negative selection	4918477
66123946	66123968	15	+	27760321	HT29	viability after 25 days	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	-0.7389358852847994	[84,66]	[40,70,43]	-6	hSpCas9	negative selection	4918478
65957630	65957652	15	+	27760321	HT29	viability after 22 days	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	0.5716428804504993	[472,368]	[599,771,801]	6	hSpCas9	negative selection	5001937
65982302	65982324	15	-	27760321	HT29	viability after 22 days	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	0.7874735861784996	[820,640]	[1672,1045,1652]	8	hSpCas9	negative selection	5001938
66119135	66119157	15	-	27760321	HT29	viability after 22 days	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.6763832966489497	[802,626]	[991,1540,1439]	7	hSpCas9	negative selection	5001939
66119157	66119179	15	-	27760321	HT29	viability after 22 days	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	0.12757684901021404	[240,187]	[376,244,186]	1	hSpCas9	negative selection	5001940
66123946	66123968	15	+	27760321	HT29	viability after 22 days	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	-0.6815152037880154	[84,66]	[11,56,96]	-5	hSpCas9	negative selection	5001941
65957630	65957652	15	+	27760321	HT29	viability after 19 days	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	0.3642600144340966	[472,368]	[630,473,749]	3	hSpCas9	negative selection	5085400
65982302	65982324	15	-	27760321	HT29	viability after 19 days	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	0.4422602180960278	[820,640]	[1548,1157,757]	4	hSpCas9	negative selection	5085401
66119135	66119157	15	-	27760321	HT29	viability after 19 days	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.9583435841830058	[802,626]	[1158,1951,1608]	8	hSpCas9	negative selection	5085402
66119157	66119179	15	-	27760321	HT29	viability after 19 days	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.42463117776817993	[240,187]	[151,157,232]	-4	hSpCas9	negative selection	5085403
66123946	66123968	15	+	27760321	HT29	viability after 19 days	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	0.04998033655981038	[84,66]	[30,172,60]	0	hSpCas9	negative selection	5085404
65957630	65957652	15	+	27760321	HT29	viability after 16 days	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	0.33785909593338637	[472,368]	[506,458,814]	4	hSpCas9	negative selection	5168863
65982302	65982324	15	-	27760321	HT29	viability after 16 days	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	0.8528289710750441	[820,640]	[1633,1433,1378]	8	hSpCas9	negative selection	5168864
66119135	66119157	15	-	27760321	HT29	viability after 16 days	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.43917725561563337	[802,626]	[1005,1132,1105]	5	hSpCas9	negative selection	5168865
66119157	66119179	15	-	27760321	HT29	viability after 16 days	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.7431840698049201	[240,187]	[61,119,240]	-6	hSpCas9	negative selection	5168866
66123946	66123968	15	+	27760321	HT29	viability after 16 days	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	-1.447926184265917	[84,66]	[17,42,30]	-8	hSpCas9	negative selection	5168867
65957630	65957652	15	+	27760321	HT29	viability after 13 days	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	0.15686100385295093	[472,368]	[426,514,682]	2	hSpCas9	negative selection	5252326
65982302	65982324	15	-	27760321	HT29	viability after 13 days	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	0.473992005678491	[820,640]	[1280,1052,1197]	6	hSpCas9	negative selection	5252327
66119135	66119157	15	-	27760321	HT29	viability after 13 days	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.7697935513460791	[802,626]	[1869,997,1375]	8	hSpCas9	negative selection	5252328
66119157	66119179	15	-	27760321	HT29	viability after 13 days	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.4143752629925552	[240,187]	[117,216,222]	-5	hSpCas9	negative selection	5252329
66123946	66123968	15	+	27760321	HT29	viability after 13 days	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	-0.7207421382381884	[84,66]	[24,70,63]	-6	hSpCas9	negative selection	5252330
65957630	65957652	15	+	27760321	HT29	viability after 10 days	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	-0.1400601990733093	[472,368]	[228,729,478]	-2	hSpCas9	negative selection	5335789
65982302	65982324	15	-	27760321	HT29	viability after 10 days	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	0.6583671396178739	[820,640]	[1310,1851,1175]	8	hSpCas9	negative selection	5335790
66119135	66119157	15	-	27760321	HT29	viability after 10 days	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.5919300247317362	[802,626]	[1336,1297,1398]	7	hSpCas9	negative selection	5335791
66119157	66119179	15	-	27760321	HT29	viability after 10 days	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.16010172030012626	[240,187]	[236,220,259]	-2	hSpCas9	negative selection	5335792
66123946	66123968	15	+	27760321	HT29	viability after 10 days	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	-1.6290908524446377	[84,66]	[32,27,30]	-8	hSpCas9	negative selection	5335793
65957630	65957652	15	+	27760321	MOLM13	viability	CATCGCCATAGTAGCCAACAGG	MEGF11	ENSG00000157890	0.7750369297938775	[575,472]	[268,703]	5	hSpCas9	negative selection	5419252
65982302	65982324	15	-	27760321	MOLM13	viability	TGCCGTGCCAGTGCCGACACGG	MEGF11	ENSG00000157890	1.164363104365067	[1024,820]	[1537,838]	7	hSpCas9	negative selection	5419253
66119135	66119157	15	-	27760321	MOLM13	viability	CCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	1.245762590889694	[961,802]	[941,1374]	8	hSpCas9	negative selection	5419254
66119157	66119179	15	-	27760321	MOLM13	viability	ATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.06604645922021901	[306,240]	[22,251]	0	hSpCas9	negative selection	5419255
66123946	66123968	15	+	27760321	MOLM13	viability	GTAATAGATCTGATCGAAGGGG	MEGF11	ENSG00000157890	-3.199417267954753	[113,84]	[11,0]	-9	hSpCas9	negative selection	5419256
66253281	66253304	15	+	27661255	K562	viability	GGGTCTTCCCCCGCACGTGGAGG	MEGF11	ENSG00000157890	-0.06883889921235037	[908,928]	[812,602]	-3	dCas9-KRAB	negative selection	5492905
66253317	66253340	15	+	27661255	K562	viability	GCATCCCGACTGCGGCCGGAGGG	MEGF11	ENSG00000157890	0.13144628795613075	[682,837]	[723,610]	4	dCas9-KRAB	negative selection	5492906
66253338	66253361	15	+	27661255	K562	viability	GGCTGCGGCTGCCCACATTGAGG	MEGF11	ENSG00000157890	-0.07398803030979062	[667,672]	[572,453]	-3	dCas9-KRAB	negative selection	5492907
66253349	66253372	15	-	27661255	K562	viability	GATGTAGGGCGCCTCAATGTGGG	MEGF11	ENSG00000157890	0.12945661582547963	[1304,1479]	[1274,1161]	4	dCas9-KRAB	negative selection	5492908
66253600	66253623	15	-	27661255	K562	viability	GGCCGGCCGCGGGAGCAGGTAGG	MEGF11	ENSG00000157890	0.207666569631076	[452,480]	[452,410]	7	dCas9-KRAB	negative selection	5492909
65982377	65982400	15	-	27260156	BXPC3	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.6795622582220913	[89]	[138,177,117,167]	9	hSpCas9	negative selection	5554969
65982417	65982440	15	+	27260156	BXPC3	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.4479484072081493	[386]	[235,374,286,286]	-7	hSpCas9	negative selection	5554970
66123943	66123966	15	+	27260156	BXPC3	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.10129446864236624	[298]	[385,224,241,304]	-2	hSpCas9	negative selection	5554971
66094450	66094473	15	-	27260156	BXPC3	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.8036091314028284	[57]	[53,147,134,86]	9	hSpCas9	negative selection	5619227
66094444	66094467	15	+	27260156	BXPC3	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.11711982608466753	[259]	[218,205,253,338]	-3	hSpCas9	negative selection	5619228
66123981	66124004	15	-	27260156	BXPC3	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.24661668899854394	[1542]	[1169,1502,1225,1565]	-5	hSpCas9	negative selection	5619229
65982377	65982400	15	-	27260156	A673	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.47118856178118906	[89]	[177,94,199,128]	9	hSpCas9	negative selection	5676220
65982417	65982440	15	+	27260156	A673	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.12505320006227516	[386]	[425,384,455,437]	-3	hSpCas9	negative selection	5676221
66123943	66123966	15	+	27260156	A673	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.4989644333969596	[298]	[283,226,193,318]	-8	hSpCas9	negative selection	5676222
66094450	66094473	15	-	27260156	A673	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.1786420407482452	[57]	[91,93,58,70]	4	hSpCas9	negative selection	5740478
66094444	66094467	15	+	27260156	A673	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.010918882544172503	[259]	[287,260,375,311]	0	hSpCas9	negative selection	5740479
66123981	66124004	15	-	27260156	A673	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.07444903798598079	[1542]	[1873,1634,1707,1838]	-2	hSpCas9	negative selection	5740480
65982377	65982400	15	-	27260156	A375	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.6136032753202121	[89]	[221,138,116,161]	8	hSpCas9	negative selection	5797471
65982417	65982440	15	+	27260156	A375	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.17990087211015637	[386]	[516,486,355,263]	-3	hSpCas9	negative selection	5797472
66123943	66123966	15	+	27260156	A375	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.6862922451067137	[298]	[162,175,201,308]	-7	hSpCas9	negative selection	5797473
66094450	66094473	15	-	27260156	A375	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.5590301828810529	[57]	[23,127,203,51]	7	hSpCas9	negative selection	5861729
66094444	66094467	15	+	27260156	A375	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.6080064512069545	[259]	[220,151,237,180]	-7	hSpCas9	negative selection	5861730
66123981	66124004	15	-	27260156	A375	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.028002560388453057	[1542]	[1637,2197,1961,1619]	0	hSpCas9	negative selection	5861731
65982377	65982400	15	-	27260156	COLO741	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	-0.09850858867132262	[89]	[113,79,126]	-2	hSpCas9	negative selection	5918722
65982417	65982440	15	+	27260156	COLO741	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	0.07782688251538628	[386]	[503,592,469]	1	hSpCas9	negative selection	5918723
66123943	66123966	15	+	27260156	COLO741	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.9001063244948182	[298]	[193,216,201]	-9	hSpCas9	negative selection	5918724
66094450	66094473	15	-	27260156	COLO741	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.8148297687876394	[57]	[178,101,114]	9	hSpCas9	negative selection	5982980
66094444	66094467	15	+	27260156	COLO741	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.2775109243718683	[259]	[238,267,308]	-5	hSpCas9	negative selection	5982981
66123981	66124004	15	-	27260156	COLO741	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.15240860024522807	[1542]	[1983,1535,1811]	-3	hSpCas9	negative selection	5982982
65982377	65982400	15	-	27260156	CAL120	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	-0.02022536882449799	[89]	[116,34,178]	0	hSpCas9	negative selection	6039973
65982417	65982440	15	+	27260156	CAL120	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	0.21679534089290234	[386]	[850,613,262]	3	hSpCas9	negative selection	6039974
66123943	66123966	15	+	27260156	CAL120	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.4968054284598087	[298]	[404,188,218]	-6	hSpCas9	negative selection	6039975
66094450	66094473	15	-	27260156	CAL120	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.5079454191955972	[57]	[117,79,111]	7	hSpCas9	negative selection	6104231
66094444	66094467	15	+	27260156	CAL120	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.0432330369638978	[259]	[298,349,290]	0	hSpCas9	negative selection	6104232
66123981	66124004	15	-	27260156	CAL120	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.06110723607777424	[1542]	[2213,1745,2078]	0	hSpCas9	negative selection	6104233
65982377	65982400	15	-	27260156	CADOES1	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.05548801561810279	[89]	[118,83,79,63]	1	hSpCas9	negative selection	6161224
65982417	65982440	15	+	27260156	CADOES1	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	1.1064637597642024	[386]	[2154,357,261,302]	9	hSpCas9	negative selection	6161225
66123943	66123966	15	+	27260156	CADOES1	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.7077916125263659	[298]	[176,203,157,140]	-8	hSpCas9	negative selection	6161226
66094450	66094473	15	-	27260156	CADOES1	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.0810472649740479	[57]	[50,52,47,76]	1	hSpCas9	negative selection	6225482
66094444	66094467	15	+	27260156	CADOES1	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.27842449175895845	[259]	[303,169,204,114]	-5	hSpCas9	negative selection	6225483
66123981	66124004	15	-	27260156	CADOES1	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.3373735613040616	[1542]	[1174,1012,1294,1056]	-5	hSpCas9	negative selection	6225484
65982377	65982400	15	-	27260156	EWS502	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	-0.05405073406448846	[89]	[73,90,70,135]	-1	hSpCas9	negative selection	6282475
65982417	65982440	15	+	27260156	EWS502	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.3977242994216621	[386]	[229,384,329,304]	-6	hSpCas9	negative selection	6282476
66123943	66123966	15	+	27260156	EWS502	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.6675149130451148	[298]	[103,215,191,302]	-8	hSpCas9	negative selection	6282477
66094450	66094473	15	-	27260156	EWS502	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.26843713934870594	[57]	[61,62,81,91]	5	hSpCas9	negative selection	6346733
66094444	66094467	15	+	27260156	EWS502	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.03045550739783387	[259]	[272,248,288,266]	0	hSpCas9	negative selection	6346734
66123981	66124004	15	-	27260156	EWS502	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.06828613242195569	[1542]	[1264,1512,1817,1682]	-1	hSpCas9	negative selection	6346735
65982377	65982400	15	-	27260156	EW8	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.39542817093752514	[89]	[144,117,30,105]	7	hSpCas9	negative selection	6403726
65982417	65982440	15	+	27260156	EW8	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	0.04542964954671702	[386]	[241,202,482,328]	0	hSpCas9	negative selection	6403727
66123943	66123966	15	+	27260156	EW8	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.6989511770065391	[298]	[174,136,139,148]	-8	hSpCas9	negative selection	6403728
66094450	66094473	15	-	27260156	EW8	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	-0.08299654728001693	[57]	[33,52,15,77]	-1	hSpCas9	negative selection	6467984
66094444	66094467	15	+	27260156	EW8	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.05406418614087383	[259]	[202,193,227,181]	-1	hSpCas9	negative selection	6467985
66123981	66124004	15	-	27260156	EW8	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.1786042204911411	[1542]	[1513,1075,823,1094]	-3	hSpCas9	negative selection	6467986
65982377	65982400	15	-	27260156	CORL105	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.13216159908396774	[89]	[132,96,72,152]	2	hSpCas9	negative selection	6524977
65982417	65982440	15	+	27260156	CORL105	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	0.010253561604625816	[386]	[467,299,525,544]	0	hSpCas9	negative selection	6524978
66123943	66123966	15	+	27260156	CORL105	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-1.1007670006774226	[298]	[177,149,115,201]	-9	hSpCas9	negative selection	6524979
66094450	66094473	15	-	27260156	CORL105	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.7916767247824881	[57]	[113,133,112,107]	9	hSpCas9	negative selection	6589235
66094444	66094467	15	+	27260156	CORL105	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.13688860559237914	[259]	[357,362,446,188]	2	hSpCas9	negative selection	6589236
66123981	66124004	15	-	27260156	CORL105	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.18107285320164612	[1542]	[1535,1419,1848,1608]	-3	hSpCas9	negative selection	6589237
65982377	65982400	15	-	27260156	HS294T	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	-0.44630922054621536	[89]	[18,28,21,33]	-6	hSpCas9	negative selection	6646228
65982417	65982440	15	+	27260156	HS294T	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.2344843423224423	[386]	[142,143,87,131]	-3	hSpCas9	negative selection	6646229
66123943	66123966	15	+	27260156	HS294T	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-1.001091625326251	[298]	[58,50,67,51]	-8	hSpCas9	negative selection	6646230
66094450	66094473	15	-	27260156	HS294T	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.1453266510125819	[57]	[17,38,18,22]	2	hSpCas9	negative selection	6710486
66094444	66094467	15	+	27260156	HS294T	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.7286384741178051	[259]	[56,70,143,455]	8	hSpCas9	negative selection	6710487
66123981	66124004	15	-	27260156	HS294T	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.12753978587944248	[1542]	[576,664,645,737]	1	hSpCas9	negative selection	6710488
65982377	65982400	15	-	27260156	HCC44	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.25948153393480533	[89]	[225,142,107,16]	4	hSpCas9	negative selection	6767479
65982417	65982440	15	+	27260156	HCC44	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.3980439043849715	[386]	[383,303,315,327]	-6	hSpCas9	negative selection	6767480
66123943	66123966	15	+	27260156	HCC44	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.5989284051240227	[298]	[179,156,262,300]	-7	hSpCas9	negative selection	6767481
66094450	66094473	15	-	27260156	HCC44	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.4267481571619207	[57]	[104,89,93,65]	7	hSpCas9	negative selection	6831737
66094444	66094467	15	+	27260156	HCC44	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.4663255623152893	[259]	[192,178,323,176]	-6	hSpCas9	negative selection	6831738
66123981	66124004	15	-	27260156	HCC44	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.09237161182387088	[1542]	[1333,1294,2278,1753]	-1	hSpCas9	negative selection	6831739
65982377	65982400	15	-	27260156	G402	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.8965205319104237	[89]	[163,92,117,418]	9	hSpCas9	negative selection	6888730
65982417	65982440	15	+	27260156	G402	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.4840212859358872	[386]	[267,355,246,462]	-6	hSpCas9	negative selection	6888731
66123943	66123966	15	+	27260156	G402	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.26652796155840797	[298]	[56,237,496,376]	-3	hSpCas9	negative selection	6888732
66094450	66094473	15	-	27260156	G402	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	1.0127121118355915	[57]	[57,163,96,235]	9	hSpCas9	negative selection	6952988
66094444	66094467	15	+	27260156	G402	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.4141409129036464	[259]	[154,334,130,319]	-5	hSpCas9	negative selection	6952989
66123981	66124004	15	-	27260156	G402	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.20758014861655827	[1542]	[2313,1826,2900,1670]	2	hSpCas9	negative selection	6952990
65982377	65982400	15	-	27260156	L33	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.12896566398000253	[89]	[72,29,31,195]	3	hSpCas9	negative selection	7009981
65982417	65982440	15	+	27260156	L33	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.406238054711456	[386]	[302,118,179,287]	-7	hSpCas9	negative selection	7009982
66123943	66123966	15	+	27260156	L33	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.6808050300834747	[298]	[177,65,163,146]	-9	hSpCas9	negative selection	7009983
66094450	66094473	15	-	27260156	L33	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	-0.2953833216404087	[57]	[54,21,30,30]	-6	hSpCas9	negative selection	7074239
66094444	66094467	15	+	27260156	L33	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.33135134692541135	[259]	[356,109,209,347]	7	hSpCas9	negative selection	7074240
66123981	66124004	15	-	27260156	L33	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.1856755845983047	[1542]	[1371,536,759,1531]	-4	hSpCas9	negative selection	7074241
65982377	65982400	15	-	27260156	K562	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	-0.1763548922745075	[89]	[69,105,110,4]	-2	hSpCas9	negative selection	7131232
65982417	65982440	15	+	27260156	K562	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.03933659553017482	[386]	[206,183,911,47]	0	hSpCas9	negative selection	7131233
66123943	66123966	15	+	27260156	K562	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	0.08869279157648557	[298]	[256,315,326,232]	1	hSpCas9	negative selection	7131234
66094450	66094473	15	-	27260156	K562	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	1.5522109673993867	[57]	[61,382,105,66]	9	hSpCas9	negative selection	7195490
66094444	66094467	15	+	27260156	K562	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.11139250249010402	[259]	[121,187,305,226]	-1	hSpCas9	negative selection	7195491
66123981	66124004	15	-	27260156	K562	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.19188196150170134	[1542]	[1508,1825,1605,1343]	2	hSpCas9	negative selection	7195492
65982377	65982400	15	-	27260156	HT29	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.06980233685839643	[89]	[163,101,69,123]	1	hSpCas9	negative selection	7252483
65982417	65982440	15	+	27260156	HT29	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.2883088842700229	[386]	[392,412,411,329]	-5	hSpCas9	negative selection	7252484
66123943	66123966	15	+	27260156	HT29	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.6982480444766974	[298]	[216,277,165,235]	-8	hSpCas9	negative selection	7252485
66094450	66094473	15	-	27260156	HT29	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.4322122767864909	[57]	[109,55,83,123]	8	hSpCas9	negative selection	7316741
66094444	66094467	15	+	27260156	HT29	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.10065264599893597	[259]	[351,229,389,368]	2	hSpCas9	negative selection	7316742
66123981	66124004	15	-	27260156	HT29	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.19438669967323086	[1542]	[1748,1787,1728,1337]	-4	hSpCas9	negative selection	7316743
65982377	65982400	15	-	27260156	MHHES1	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.3361960842414615	[89]	[232,131,132,43]	6	hSpCas9	negative selection	7373734
65982417	65982440	15	+	27260156	MHHES1	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.15547741321127467	[386]	[423,264,609,276]	-3	hSpCas9	negative selection	7373735
66123943	66123966	15	+	27260156	MHHES1	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.13129260883260652	[298]	[325,275,343,281]	-2	hSpCas9	negative selection	7373736
66094450	66094473	15	-	27260156	MHHES1	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.046299758425806026	[57]	[35,75,98,56]	0	hSpCas9	negative selection	7437992
66094444	66094467	15	+	27260156	MHHES1	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.12637912516776884	[259]	[339,258,271,215]	-2	hSpCas9	negative selection	7437993
66123981	66124004	15	-	27260156	MHHES1	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.2551438926474965	[1542]	[2411,1330,1122,1107]	-5	hSpCas9	negative selection	7437994
65982377	65982400	15	-	27260156	MEWO	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	-0.30463505123826184	[89]	[65,84,52]	-6	hSpCas9	negative selection	7494985
65982417	65982440	15	+	27260156	MEWO	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.1708938356287884	[386]	[387,247,341]	-4	hSpCas9	negative selection	7494986
66123943	66123966	15	+	27260156	MEWO	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.4765154211341147	[298]	[158,190,244]	-7	hSpCas9	negative selection	7494987
66094450	66094473	15	-	27260156	MEWO	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	-0.1700561213231162	[57]	[85,46,18]	-4	hSpCas9	negative selection	7559243
66094444	66094467	15	+	27260156	MEWO	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.12240885005591196	[259]	[247,239,186]	-3	hSpCas9	negative selection	7559244
66123981	66124004	15	-	27260156	MEWO	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.18673340731083843	[1542]	[1492,1305,1048]	-4	hSpCas9	negative selection	7559245
65982377	65982400	15	-	27260156	LNCAPCLONEFGC	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.11049260799298954	[89]	[127,83,50,82]	1	hSpCas9	negative selection	7616236
65982417	65982440	15	+	27260156	LNCAPCLONEFGC	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	0.15132367791758933	[386]	[378,356,426,401]	2	hSpCas9	negative selection	7616237
66123943	66123966	15	+	27260156	LNCAPCLONEFGC	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.7777672423109845	[298]	[190,120,227,103]	-8	hSpCas9	negative selection	7616238
66094450	66094473	15	-	27260156	LNCAPCLONEFGC	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.4199316129329249	[57]	[60,78,24,108]	6	hSpCas9	negative selection	7680494
66094444	66094467	15	+	27260156	LNCAPCLONEFGC	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.6233950431433757	[259]	[128,145,264,88]	-7	hSpCas9	negative selection	7680495
66123981	66124004	15	-	27260156	LNCAPCLONEFGC	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.006370916822619588	[1542]	[1474,1142,1659,1341]	0	hSpCas9	negative selection	7680496
65982377	65982400	15	-	27260156	PANC0327	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.2515390000970754	[89]	[43,82,90,159]	4	hSpCas9	negative selection	7737487
65982417	65982440	15	+	27260156	PANC0327	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	0.15127728823199743	[386]	[230,357,549,378]	2	hSpCas9	negative selection	7737488
66123943	66123966	15	+	27260156	PANC0327	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	0.2242685744280834	[298]	[659,158,178,290]	3	hSpCas9	negative selection	7737489
66094450	66094473	15	-	27260156	PANC0327	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.13306165753968635	[57]	[13,114,71,13]	2	hSpCas9	negative selection	7801745
66094444	66094467	15	+	27260156	PANC0327	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.28551487557928457	[259]	[212,484,214,180]	4	hSpCas9	negative selection	7801746
66123981	66124004	15	-	27260156	PANC0327	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.09495391388841745	[1542]	[1541,1136,1212,2010]	1	hSpCas9	negative selection	7801747
65982377	65982400	15	-	27260156	NCIH2009	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.45120247476720077	[89]	[246,132,150]	6	hSpCas9	negative selection	7858738
65982417	65982440	15	+	27260156	NCIH2009	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	0.5391521930205498	[386]	[720,1059,556]	7	hSpCas9	negative selection	7858739
66123943	66123966	15	+	27260156	NCIH2009	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.607023298453452	[298]	[280,311,229]	-6	hSpCas9	negative selection	7858740
66094450	66094473	15	-	27260156	NCIH2009	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	1.1364321952692316	[57]	[215,211,112]	9	hSpCas9	negative selection	7922996
66094444	66094467	15	+	27260156	NCIH2009	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.5764540156989684	[259]	[245,291,191]	-6	hSpCas9	negative selection	7922997
66123981	66124004	15	-	27260156	NCIH2009	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.11090880030795547	[1542]	[2380,2203,2407]	1	hSpCas9	negative selection	7922998
65982377	65982400	15	-	27260156	NCIH1373	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.502717732401456	[89]	[220,102,220,8]	5	hSpCas9	negative selection	7979989
65982417	65982440	15	+	27260156	NCIH1373	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	0.11399806102657484	[386]	[655,538,395,77]	1	hSpCas9	negative selection	7979990
66123943	66123966	15	+	27260156	NCIH1373	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-1.3993719871030572	[298]	[287,54,79,30]	-8	hSpCas9	negative selection	7979991
66094450	66094473	15	-	27260156	NCIH1373	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	-0.251358305821896	[57]	[47,61,73,7]	-3	hSpCas9	negative selection	8044247
66094444	66094467	15	+	27260156	NCIH1373	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.7088414902363145	[259]	[226,205,144,35]	-6	hSpCas9	negative selection	8044248
66123981	66124004	15	-	27260156	NCIH1373	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.1418887338810979	[1542]	[1873,1138,1735,421]	-1	hSpCas9	negative selection	8044249
65982377	65982400	15	-	27260156	PATU8902	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	-0.08665334717141127	[89]	[163,65,73,185]	-1	hSpCas9	negative selection	8101240
65982417	65982440	15	+	27260156	PATU8902	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.2851630237037953	[386]	[510,309,398,570]	-3	hSpCas9	negative selection	8101241
66123943	66123966	15	+	27260156	PATU8902	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.37258328958933196	[298]	[632,358,81,260]	-4	hSpCas9	negative selection	8101242
66094450	66094473	15	-	27260156	PATU8902	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	-0.8018446449214194	[57]	[114,60,5,7]	-6	hSpCas9	negative selection	8165498
66094444	66094467	15	+	27260156	PATU8902	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.35256899476346737	[259]	[414,311,123,325]	-4	hSpCas9	negative selection	8165499
66123981	66124004	15	-	27260156	PATU8902	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.2794724801131985	[1542]	[2098,2017,1295,1774]	-3	hSpCas9	negative selection	8165500
65982377	65982400	15	-	27260156	PANC1	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	1.0464858565010775	[89]	[130,210,164,142]	9	hSpCas9	negative selection	8222491
65982417	65982440	15	+	27260156	PANC1	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.32687987067958335	[386]	[296,396,228,173]	-5	hSpCas9	negative selection	8222492
66123943	66123966	15	+	27260156	PANC1	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.585798193457685	[298]	[151,205,119,204]	-7	hSpCas9	negative selection	8222493
66094450	66094473	15	-	27260156	PANC1	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.15698249139521048	[57]	[26,58,42,87]	2	hSpCas9	negative selection	8286749
66094444	66094467	15	+	27260156	PANC1	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.3816297854141185	[259]	[275,449,220,250]	6	hSpCas9	negative selection	8286750
66123981	66124004	15	-	27260156	PANC1	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.021893650585803837	[1542]	[1126,1887,1340,1015]	0	hSpCas9	negative selection	8286751
65982377	65982400	15	-	27260156	PANC0813	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	-0.05669339400412543	[89]	[136,67,90,112]	-1	hSpCas9	negative selection	8343742
65982417	65982440	15	+	27260156	PANC0813	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	0.07256883372555628	[386]	[482,535,577,323]	1	hSpCas9	negative selection	8343743
66123943	66123966	15	+	27260156	PANC0813	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-1.2719436196143203	[298]	[121,132,152,169]	-9	hSpCas9	negative selection	8343744
66094450	66094473	15	-	27260156	PANC0813	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	-0.2029331883433736	[57]	[50,81,63,39]	-3	hSpCas9	negative selection	8408000
66094444	66094467	15	+	27260156	PANC0813	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.07021342326403623	[259]	[578,297,194,237]	1	hSpCas9	negative selection	8408001
66123981	66124004	15	-	27260156	PANC0813	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.12778485137151185	[1542]	[1572,2078,1659,1330]	-2	hSpCas9	negative selection	8408002
65982377	65982400	15	-	27260156	RDES	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.5061526771518967	[89]	[89,154,211,139]	7	hSpCas9	negative selection	8464993
65982417	65982440	15	+	27260156	RDES	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.4300468622498599	[386]	[244,315,370,413]	-6	hSpCas9	negative selection	8464994
66123943	66123966	15	+	27260156	RDES	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.770981495652959	[298]	[178,171,179,288]	-8	hSpCas9	negative selection	8464995
66094450	66094473	15	-	27260156	RDES	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.8815516253789788	[57]	[75,148,153,116]	9	hSpCas9	negative selection	8529251
66094444	66094467	15	+	27260156	RDES	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.47299904475474985	[259]	[182,247,221,203]	-7	hSpCas9	negative selection	8529252
66123981	66124004	15	-	27260156	RDES	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.37761695298606646	[1542]	[1053,1341,1551,1584]	-6	hSpCas9	negative selection	8529253
65982377	65982400	15	-	27260156	PC3	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.44350701675588233	[89]	[72,153,113,152]	8	hSpCas9	negative selection	8586244
65982417	65982440	15	+	27260156	PC3	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.24628731310588825	[386]	[211,363,570,260]	-5	hSpCas9	negative selection	8586245
66123943	66123966	15	+	27260156	PC3	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.3040503987958021	[298]	[148,309,343,213]	-6	hSpCas9	negative selection	8586246
66094450	66094473	15	-	27260156	PC3	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.5427438123790957	[57]	[37,92,186,71]	9	hSpCas9	negative selection	8650502
66094444	66094467	15	+	27260156	PC3	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.03314511481960225	[259]	[165,198,501,309]	0	hSpCas9	negative selection	8650503
66123981	66124004	15	-	27260156	PC3	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.08795703946061328	[1542]	[916,1138,2314,1883]	-2	hSpCas9	negative selection	8650504
65982377	65982400	15	-	27260156	PATU8988T	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	-0.11041024139519973	[89]	[114,86,24,97]	-2	hSpCas9	negative selection	8707495
65982417	65982440	15	+	27260156	PATU8988T	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.009459738772501392	[386]	[281,429,279,511]	0	hSpCas9	negative selection	8707496
66123943	66123966	15	+	27260156	PATU8988T	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.5292330444456765	[298]	[173,223,164,243]	-7	hSpCas9	negative selection	8707497
66094450	66094473	15	-	27260156	PATU8988T	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	-0.11070793308877436	[57]	[63,50,66,22]	-2	hSpCas9	negative selection	8771753
66094444	66094467	15	+	27260156	PATU8988T	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.056582306306808605	[259]	[170,273,298,222]	-1	hSpCas9	negative selection	8771754
66123981	66124004	15	-	27260156	PATU8988T	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.2145901781487094	[1542]	[1433,1156,1417,1101]	-4	hSpCas9	negative selection	8771755
65982377	65982400	15	-	27260156	T47D	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.2743043907381435	[89]	[140,112,115,138]	6	hSpCas9	negative selection	8828746
65982417	65982440	15	+	27260156	T47D	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.09313447277574932	[386]	[482,323,420,472]	-2	hSpCas9	negative selection	8828747
66123943	66123966	15	+	27260156	T47D	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.41083140577858823	[298]	[278,200,301,270]	-7	hSpCas9	negative selection	8828748
66094450	66094473	15	-	27260156	T47D	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.30211743475583663	[57]	[84,68,101,77]	6	hSpCas9	negative selection	8893004
66094444	66094467	15	+	27260156	T47D	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.2373135205837078	[259]	[250,258,269,246]	-5	hSpCas9	negative selection	8893005
66123981	66124004	15	-	27260156	T47D	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.21785192463745728	[1542]	[1611,1419,1515,1648]	-5	hSpCas9	negative selection	8893006
65982377	65982400	15	-	27260156	SU8686	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.30084552665555275	[89]	[105,78,145,113]	5	hSpCas9	negative selection	8949997
65982417	65982440	15	+	27260156	SU8686	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.29257951918516945	[386]	[214,447,241,341]	-5	hSpCas9	negative selection	8949998
66123943	66123966	15	+	27260156	SU8686	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.8046741942634772	[298]	[144,175,158,204]	-8	hSpCas9	negative selection	8949999
66094450	66094473	15	-	27260156	SU8686	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.2682464458055227	[57]	[65,69,26,120]	4	hSpCas9	negative selection	9014255
66094444	66094467	15	+	27260156	SU8686	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.34795314725898796	[259]	[338,254,267,478]	6	hSpCas9	negative selection	9014256
66123981	66124004	15	-	27260156	SU8686	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.0566729240713566	[1542]	[1339,1419,1801,1896]	0	hSpCas9	negative selection	9014257
65982377	65982400	15	-	27260156	SKES1	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	-0.326303450806134	[89]	[68,84,60,71]	-6	hSpCas9	negative selection	9071248
65982417	65982440	15	+	27260156	SKES1	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.5236132793092985	[386]	[262,323,275,219]	-8	hSpCas9	negative selection	9071249
66123943	66123966	15	+	27260156	SKES1	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.7261291626333359	[298]	[319,125,146,143]	-9	hSpCas9	negative selection	9071250
66094450	66094473	15	-	27260156	SKES1	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.6489905584996212	[57]	[92,49,92,117]	9	hSpCas9	negative selection	9135506
66094444	66094467	15	+	27260156	SKES1	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.06647174591209903	[259]	[310,262,322,198]	1	hSpCas9	negative selection	9135507
66123981	66124004	15	-	27260156	SKES1	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.049120525043199637	[1542]	[1521,1479,1551,1394]	-1	hSpCas9	negative selection	9135508
65982377	65982400	15	-	27260156	TOV112D	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	-0.10035653130070754	[89]	[78,116,104,43]	-2	hSpCas9	negative selection	9192499
65982417	65982440	15	+	27260156	TOV112D	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.386385379808609	[386]	[268,468,199,287]	-6	hSpCas9	negative selection	9192500
66123943	66123966	15	+	27260156	TOV112D	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.39993619580647377	[298]	[211,244,311,143]	-7	hSpCas9	negative selection	9192501
66094450	66094473	15	-	27260156	TOV112D	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.01417867855210142	[57]	[19,54,45,107]	0	hSpCas9	negative selection	9256757
66094444	66094467	15	+	27260156	TOV112D	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	0.13433572142774675	[259]	[413,250,229,250]	2	hSpCas9	negative selection	9256758
66123981	66124004	15	-	27260156	TOV112D	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.08709593222740808	[1542]	[1278,1827,1185,1596]	-2	hSpCas9	negative selection	9256759
65982377	65982400	15	-	27260156	TC71	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.2914477476514601	[89]	[112,101,105,153]	7	hSpCas9	negative selection	9313750
65982417	65982440	15	+	27260156	TC71	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	0.05662987138335607	[386]	[432,354,387,558]	1	hSpCas9	negative selection	9313751
66123943	66123966	15	+	27260156	TC71	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.22435756747065383	[298]	[330,195,238,334]	-5	hSpCas9	negative selection	9313752
66094450	66094473	15	-	27260156	TC71	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.46354729291772223	[57]	[122,66,63,88]	9	hSpCas9	negative selection	9378008
66094444	66094467	15	+	27260156	TC71	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.13934843315830825	[259]	[269,199,283,256]	-4	hSpCas9	negative selection	9378009
66123981	66124004	15	-	27260156	TC71	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	-0.16270983349089696	[1542]	[1540,1619,1300,1450]	-4	hSpCas9	negative selection	9378010
65982377	65982400	15	-	27260156	TC32	viability	GTGTGCGCCGCCGGCTTCCGTGG	MEGF11	ENSG00000157890	0.4316514925759749	[89]	[91,76,202,109]	7	hSpCas9	negative selection	9435001
65982417	65982440	15	+	27260156	TC32	viability	GGTTACACAGGGCGCCGTTCTGG	MEGF11	ENSG00000157890	-0.24074149691745317	[386]	[281,221,303,447]	-4	hSpCas9	negative selection	9435002
66123943	66123966	15	+	27260156	TC32	viability	TGTGTAATAGATCTGATCGAAGG	MEGF11	ENSG00000157890	-0.4577500274910833	[298]	[178,174,343,142]	-7	hSpCas9	negative selection	9435003
66094450	66094473	15	-	27260156	TC32	viability	GCACGGCCGCTGCGTTTCCCCGG	MEGF11	ENSG00000157890	0.6861893767796441	[57]	[121,44,61,125]	9	hSpCas9	negative selection	9499259
66094444	66094467	15	+	27260156	TC32	viability	AGGTGTCCGGGGAAACGCAGCGG	MEGF11	ENSG00000157890	-0.0482278853988759	[259]	[207,244,251,226]	-1	hSpCas9	negative selection	9499260
66123981	66124004	15	-	27260156	TC32	viability	CAGCTATGCTGTGACTGTCCAGG	MEGF11	ENSG00000157890	0.007377898310013453	[1542]	[1420,1069,1763,1705]	0	hSpCas9	negative selection	9499261
65980767	65980790	15	+	27869803	HPAFII	viability after 27 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	-0.45627873406139496	[171]	[78,54,NaN]	-3	hSpCas9	negative selection	9554410
65982367	65982390	15	+	27869803	HPAFII	viability after 27 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	-0.1527162119677552	[622]	[238,340,NaN]	-1	hSpCas9	negative selection	9554411
66094471	66094494	15	+	27869803	HPAFII	viability after 27 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.12655370739496719	[516]	[197,378,NaN]	1	hSpCas9	negative selection	9554412
66119157	66119180	15	-	27869803	HPAFII	viability after 27 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	0.27755304086911403	[200]	[150,108,NaN]	2	hSpCas9	negative selection	9554413
66123898	66123921	15	-	27869803	HPAFII	viability after 27 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	1.9658504713034208	[92]	[214,170,NaN]	9	hSpCas9	negative selection	9554414
66128295	66128318	15	+	27869803	HPAFII	viability after 27 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	0.4801854068165051	[372]	[482,98,NaN]	4	hSpCas9	negative selection	9554415
65980767	65980790	15	+	27869803	HPAFII	viability after 15 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.27068372165213866	[171]	[259,199,NaN]	3	hSpCas9	negative selection	9636859
65982367	65982390	15	+	27869803	HPAFII	viability after 15 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	-0.074412149919868	[622]	[958,434,NaN]	-1	hSpCas9	negative selection	9636860
66094471	66094494	15	+	27869803	HPAFII	viability after 15 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.03992345729574054	[516]	[844,400,NaN]	0	hSpCas9	negative selection	9636861
66119157	66119180	15	-	27869803	HPAFII	viability after 15 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	0.27194217897367856	[200]	[229,279,NaN]	3	hSpCas9	negative selection	9636862
66123898	66123921	15	-	27869803	HPAFII	viability after 15 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.67170431960718	[92]	[321,57,NaN]	7	hSpCas9	negative selection	9636863
66128295	66128318	15	+	27869803	HPAFII	viability after 15 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	0.2644282330553509	[372]	[803,280,NaN]	3	hSpCas9	negative selection	9636864
65980767	65980790	15	+	27869803	ASPC1	viability after 36 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.47697256288966283	[409]	[479,90,85]	5	hSpCas9	negative selection	9719308
65982367	65982390	15	+	27869803	ASPC1	viability after 36 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.011226999509370117	[1286]	[248,749,354]	0	hSpCas9	negative selection	9719309
66094471	66094494	15	+	27869803	ASPC1	viability after 36 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.2947112458457932	[1564]	[353,303,616]	-3	hSpCas9	negative selection	9719310
66119157	66119180	15	-	27869803	ASPC1	viability after 36 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	0.1362996197300707	[627]	[353,201,189]	1	hSpCas9	negative selection	9719311
66123898	66123921	15	-	27869803	ASPC1	viability after 36 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.7074762034417904	[270]	[90,290,88]	7	hSpCas9	negative selection	9719312
66128295	66128318	15	+	27869803	ASPC1	viability after 36 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.3272274890855671	[1199]	[428,374,230]	-3	hSpCas9	negative selection	9719313
65980767	65980790	15	+	27869803	PATU8988S	viability after 35 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.8223999328052434	[389]	[390,163,NaN]	8	hSpCas9	negative selection	9801757
65982367	65982390	15	+	27869803	PATU8988S	viability after 35 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	-0.1642221629925693	[1294]	[441,488,NaN]	-2	hSpCas9	negative selection	9801758
66094471	66094494	15	+	27869803	PATU8988S	viability after 35 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.7963353858261819	[1292]	[236,362,NaN]	-7	hSpCas9	negative selection	9801759
66119157	66119180	15	-	27869803	PATU8988S	viability after 35 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.7390150429462289	[558]	[86,182,NaN]	-6	hSpCas9	negative selection	9801760
66123898	66123921	15	-	27869803	PATU8988S	viability after 35 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	-0.07514392886133159	[288]	[104,115,NaN]	-1	hSpCas9	negative selection	9801761
66128295	66128318	15	+	27869803	PATU8988S	viability after 35 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.7407450834057333	[962]	[275,187,NaN]	-6	hSpCas9	negative selection	9801762
65980767	65980790	15	+	27869803	PATU8988S	viability after 31 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	0.03602638007527614	[389]	[169,145,NaN]	0	hSpCas9	negative selection	9884206
65982367	65982390	15	+	27869803	PATU8988S	viability after 31 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.03878249118859989	[1294]	[346,763,NaN]	0	hSpCas9	negative selection	9884207
66094471	66094494	15	+	27869803	PATU8988S	viability after 31 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.481605191894275	[1292]	[392,338,NaN]	-5	hSpCas9	negative selection	9884208
66119157	66119180	15	-	27869803	PATU8988S	viability after 31 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	-0.7607089172065487	[558]	[109,158,NaN]	-7	hSpCas9	negative selection	9884209
66123898	66123921	15	-	27869803	PATU8988S	viability after 31 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	0.17604674148897848	[288]	[94,174,NaN]	2	hSpCas9	negative selection	9884210
66128295	66128318	15	+	27869803	PATU8988S	viability after 31 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	-0.44886950852824187	[962]	[268,296,NaN]	-5	hSpCas9	negative selection	9884211
65980767	65980790	15	+	27869803	HPAFII	viability after 35 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	-0.448548684223803	[171]	[28,102,NaN]	-3	hSpCas9	negative selection	9966655
65982367	65982390	15	+	27869803	HPAFII	viability after 35 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	0.1311211707274571	[622]	[200,507,NaN]	0	hSpCas9	negative selection	9966656
66094471	66094494	15	+	27869803	HPAFII	viability after 35 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	-0.16229845379029428	[516]	[112,369,NaN]	-1	hSpCas9	negative selection	9966657
66119157	66119180	15	-	27869803	HPAFII	viability after 35 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	0.13681259033240015	[200]	[101,122,NaN]	0	hSpCas9	negative selection	9966658
66123898	66123921	15	-	27869803	HPAFII	viability after 35 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	2.510656365077721	[92]	[169,378,NaN]	9	hSpCas9	negative selection	9966659
66128295	66128318	15	+	27869803	HPAFII	viability after 35 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	0.4597128251329944	[372]	[349,157,NaN]	3	hSpCas9	negative selection	9966660
65980767	65980790	15	+	27869803	HPAFII	viability after 31 days	GGCCCACTTACCGTCCAGCCTGG	MEGF11	ENSG00000157890	-1.2550805380660597	[171]	[27,53,NaN]	-6	hSpCas9	negative selection	10049104
65982367	65982390	15	+	27869803	HPAFII	viability after 31 days	GCAGCGCCATCCACGGAAGCCGG	MEGF11	ENSG00000157890	-0.14069562140323666	[622]	[219,422,NaN]	-1	hSpCas9	negative selection	10049105
66094471	66094494	15	+	27869803	HPAFII	viability after 31 days	GCACACACTCCTCCGTACACAGG	MEGF11	ENSG00000157890	0.03346165403678092	[516]	[94,516,NaN]	0	hSpCas9	negative selection	10049106
66119157	66119180	15	-	27869803	HPAFII	viability after 31 days	TATAAGACGGCGTATCGGAGAGG	MEGF11	ENSG00000157890	0.03138944971650531	[200]	[143,83,NaN]	0	hSpCas9	negative selection	10049107
66123898	66123921	15	-	27869803	HPAFII	viability after 31 days	GGTTCAAGTGCACCAGGCACCGG	MEGF11	ENSG00000157890	2.3186793011703397	[92]	[212,311,NaN]	9	hSpCas9	negative selection	10049108
66128295	66128318	15	+	27869803	HPAFII	viability after 31 days	CCACACCTTACCTCTCCCAGTGG	MEGF11	ENSG00000157890	0.05027510494766707	[372]	[322,100,NaN]	0	hSpCas9	negative selection	10049109
65982321	65982344	15	+	28162770	P31FUJ	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	-0.037671863082388346	[144]	[165]	0	hSpCas9	negative selection	10190912
65916838	65916861	15	+	28162770	P31FUJ	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	-0.7054617355107425	[314]	[226]	-5	hSpCas9	negative selection	10190913
66119135	66119158	15	-	28162770	P31FUJ	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.403175582167001	[425]	[661]	4	hSpCas9	negative selection	10190914
65982370	65982393	15	+	28162770	P31FUJ	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	-0.13110680734502766	[177]	[190]	-1	hSpCas9	negative selection	10190915
65982332	65982355	15	-	28162770	P31FUJ	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	0.8805795950033639	[158]	[343]	8	hSpCas9	negative selection	10190916
65964966	65964989	15	-	28162770	P31FUJ	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	0.988138082888157	[141]	[330]	9	hSpCas9	negative selection	10190917
65957648	65957671	15	+	28162770	P31FUJ	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	-0.19993757050875194	[216]	[221]	-2	hSpCas9	negative selection	10190918
65957573	65957596	15	-	28162770	P31FUJ	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	-0.19363160713370087	[326]	[335]	-2	hSpCas9	negative selection	10190919
65922444	65922467	15	+	28162770	P31FUJ	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	-0.07441223333854385	[292]	[326]	0	hSpCas9	negative selection	10190920
65922350	65922373	15	+	28162770	P31FUJ	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	0.0891258904729837	[63]	[79]	0	hSpCas9	negative selection	10190921
65982321	65982344	15	+	28162770	TF1	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10360278
65916838	65916861	15	+	28162770	TF1	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	NaN	[NaN]	[178]	1	hSpCas9	negative selection	10360279
66119135	66119158	15	-	28162770	TF1	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	NaN	[NaN]	[244]	1	hSpCas9	negative selection	10360280
65982370	65982393	15	+	28162770	TF1	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	NaN	[NaN]	[241]	1	hSpCas9	negative selection	10360281
65982332	65982355	15	-	28162770	TF1	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10360282
65964966	65964989	15	-	28162770	TF1	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10360283
65957648	65957671	15	+	28162770	TF1	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	NaN	[NaN]	[185]	1	hSpCas9	negative selection	10360284
65957573	65957596	15	-	28162770	TF1	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	NaN	[NaN]	[286]	1	hSpCas9	negative selection	10360285
65922444	65922467	15	+	28162770	TF1	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	NaN	[NaN]	[238]	1	hSpCas9	negative selection	10360286
65922350	65922373	15	+	28162770	TF1	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10360287
65982321	65982344	15	+	28162770	SKM1	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	0.554374180887733	[51]	[134]	5	hSpCas9	negative selection	10529644
65916838	65916861	15	+	28162770	SKM1	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	-0.8880908884797778	[66]	[63]	-6	hSpCas9	negative selection	10529645
66119135	66119158	15	-	28162770	SKM1	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.2608247331076151	[109]	[232]	2	hSpCas9	negative selection	10529646
65982370	65982393	15	+	28162770	SKM1	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	0.04049477822805958	[43]	[79]	0	hSpCas9	negative selection	10529647
65982332	65982355	15	-	28162770	SKM1	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	-0.3645289324227651	[66]	[91]	-3	hSpCas9	negative selection	10529648
65964966	65964989	15	-	28162770	SKM1	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	0.19548572870683556	[40]	[82]	2	hSpCas9	negative selection	10529649
65957648	65957671	15	+	28162770	SKM1	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	0.03902188882918403	[48]	[88]	0	hSpCas9	negative selection	10529650
65957573	65957596	15	-	28162770	SKM1	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	0.510194732319184	[55]	[140]	5	hSpCas9	negative selection	10529651
65922444	65922467	15	+	28162770	SKM1	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	0.43097904314786545	[59]	[142]	4	hSpCas9	negative selection	10529652
65922350	65922373	15	+	28162770	SKM1	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	0.8660542956632542	[26]	[86]	7	hSpCas9	negative selection	10529653
65982321	65982344	15	+	28162770	SKM1	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	0.554374180887733	[51]	[134]	5	hSpCas9	negative selection	10699010
65916838	65916861	15	+	28162770	SKM1	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	-0.8880908884797778	[66]	[63]	-6	hSpCas9	negative selection	10699011
66119135	66119158	15	-	28162770	SKM1	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.2608247331076151	[109]	[232]	2	hSpCas9	negative selection	10699012
65982370	65982393	15	+	28162770	SKM1	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	0.04049477822805958	[43]	[79]	0	hSpCas9	negative selection	10699013
65982332	65982355	15	-	28162770	SKM1	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	-0.3645289324227651	[66]	[91]	-3	hSpCas9	negative selection	10699014
65964966	65964989	15	-	28162770	SKM1	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	0.19548572870683556	[40]	[82]	2	hSpCas9	negative selection	10699015
65957648	65957671	15	+	28162770	SKM1	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	0.03902188882918403	[48]	[88]	0	hSpCas9	negative selection	10699016
65957573	65957596	15	-	28162770	SKM1	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	0.510194732319184	[55]	[140]	5	hSpCas9	negative selection	10699017
65922444	65922467	15	+	28162770	SKM1	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	0.43097904314786545	[59]	[142]	4	hSpCas9	negative selection	10699018
65922350	65922373	15	+	28162770	SKM1	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	0.8660542956632542	[26]	[86]	7	hSpCas9	negative selection	10699019
65982321	65982344	15	+	28162770	PL21	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	-0.27379157384309216	[174]	[62]	-2	hSpCas9	negative selection	10868376
65916838	65916861	15	+	28162770	PL21	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	0.44380869545618284	[249]	[147]	4	hSpCas9	negative selection	10868377
66119135	66119158	15	-	28162770	PL21	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.21307867019681814	[443]	[223]	2	hSpCas9	negative selection	10868378
65982370	65982393	15	+	28162770	PL21	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	-0.4462234308959792	[143]	[45]	-3	hSpCas9	negative selection	10868379
65982332	65982355	15	-	28162770	PL21	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	-0.18377536729374308	[213]	[81]	-1	hSpCas9	negative selection	10868380
65964966	65964989	15	-	28162770	PL21	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	0.16061125030268264	[110]	[53]	1	hSpCas9	negative selection	10868381
65957648	65957671	15	+	28162770	PL21	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	-0.9224796721746354	[134]	[30]	-6	hSpCas9	negative selection	10868382
65957573	65957596	15	-	28162770	PL21	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	-0.2873063803175738	[285]	[101]	-2	hSpCas9	negative selection	10868383
65922444	65922467	15	+	28162770	PL21	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	1.136945788002126	[139]	[133]	8	hSpCas9	negative selection	10868384
65922350	65922373	15	+	28162770	PL21	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	-2.79986038551068	[79]	[4]	-9	hSpCas9	negative selection	10868385
65982321	65982344	15	+	28162770	P31FUJ	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	-0.037671863082388346	[144]	[165]	0	hSpCas9	negative selection	11037742
65916838	65916861	15	+	28162770	P31FUJ	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	-0.7054617355107425	[314]	[226]	-5	hSpCas9	negative selection	11037743
66119135	66119158	15	-	28162770	P31FUJ	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.403175582167001	[425]	[661]	4	hSpCas9	negative selection	11037744
65982370	65982393	15	+	28162770	P31FUJ	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	-0.13110680734502766	[177]	[190]	-1	hSpCas9	negative selection	11037745
65982332	65982355	15	-	28162770	P31FUJ	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	0.8805795950033639	[158]	[343]	8	hSpCas9	negative selection	11037746
65964966	65964989	15	-	28162770	P31FUJ	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	0.988138082888157	[141]	[330]	9	hSpCas9	negative selection	11037747
65957648	65957671	15	+	28162770	P31FUJ	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	-0.19993757050875194	[216]	[221]	-2	hSpCas9	negative selection	11037748
65957573	65957596	15	-	28162770	P31FUJ	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	-0.19363160713370087	[326]	[335]	-2	hSpCas9	negative selection	11037749
65922444	65922467	15	+	28162770	P31FUJ	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	-0.07441223333854385	[292]	[326]	0	hSpCas9	negative selection	11037750
65922350	65922373	15	+	28162770	P31FUJ	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	0.0891258904729837	[63]	[79]	0	hSpCas9	negative selection	11037751
65982321	65982344	15	+	28162770	OCIAML5	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	0.7802016446355158	[59]	[185]	6	hSpCas9	negative selection	11207108
65916838	65916861	15	+	28162770	OCIAML5	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	0.7152372633606525	[136]	[405]	6	hSpCas9	negative selection	11207109
66119135	66119158	15	-	28162770	OCIAML5	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.6822698567871911	[202]	[587]	6	hSpCas9	negative selection	11207110
65982370	65982393	15	+	28162770	OCIAML5	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	0.76546379231359	[72]	[223]	6	hSpCas9	negative selection	11207111
65982332	65982355	15	-	28162770	OCIAML5	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	-1.5277945355083355	[122]	[76]	-7	hSpCas9	negative selection	11207112
65964966	65964989	15	-	28162770	OCIAML5	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	1.2227011975379753	[46]	[197]	9	hSpCas9	negative selection	11207113
65957648	65957671	15	+	28162770	OCIAML5	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	0.6701601745091967	[93]	[269]	6	hSpCas9	negative selection	11207114
65957573	65957596	15	-	28162770	OCIAML5	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	-0.07924405476582175	[150]	[257]	0	hSpCas9	negative selection	11207115
65922444	65922467	15	+	28162770	OCIAML5	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	0.6497546945569134	[124]	[353]	5	hSpCas9	negative selection	11207116
65922350	65922373	15	+	28162770	OCIAML5	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	-1.2608721164313264	[76]	[57]	-6	hSpCas9	negative selection	11207117
65982321	65982344	15	+	28162770	EOL1	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	0.032607517427987454	[359]	[193]	0	hSpCas9	negative selection	11376474
65916838	65916861	15	+	28162770	EOL1	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	-0.2962583988739618	[302]	[129]	-2	hSpCas9	negative selection	11376475
66119135	66119158	15	-	28162770	EOL1	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.7515518049162886	[822]	[729]	6	hSpCas9	negative selection	11376476
65982370	65982393	15	+	28162770	EOL1	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	0.3510262113860927	[313]	[210]	3	hSpCas9	negative selection	11376477
65982332	65982355	15	-	28162770	EOL1	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	0.4839751801845533	[379]	[279]	4	hSpCas9	negative selection	11376478
65964966	65964989	15	-	28162770	EOL1	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	0.4888112796238546	[233]	[172]	4	hSpCas9	negative selection	11376479
65957648	65957671	15	+	28162770	EOL1	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	-0.29177013535622887	[157]	[67]	-2	hSpCas9	negative selection	11376480
65957573	65957596	15	-	28162770	EOL1	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	0.5627032114572841	[283]	[220]	5	hSpCas9	negative selection	11376481
65922444	65922467	15	+	28162770	EOL1	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	0.6916246827419171	[274]	[233]	6	hSpCas9	negative selection	11376482
65922350	65922373	15	+	28162770	EOL1	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	1.1051200172123554	[59]	[67]	8	hSpCas9	negative selection	11376483
65982321	65982344	15	+	28162770	MOLM13	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	0.1767235404279036	[289]	[236]	1	hSpCas9	negative selection	11545840
65916838	65916861	15	+	28162770	MOLM13	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	0.9508799091644574	[253]	[354]	7	hSpCas9	negative selection	11545841
66119135	66119158	15	-	28162770	MOLM13	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.4730510866603579	[557]	[559]	3	hSpCas9	negative selection	11545842
65982370	65982393	15	+	28162770	MOLM13	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	1.4283610173579413	[221]	[431]	9	hSpCas9	negative selection	11545843
65982332	65982355	15	-	28162770	MOLM13	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	0.9931721975289338	[254]	[366]	7	hSpCas9	negative selection	11545844
65964966	65964989	15	-	28162770	MOLM13	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	1.3875877534537175	[156]	[296]	9	hSpCas9	negative selection	11545845
65957648	65957671	15	+	28162770	MOLM13	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	0.8953106052792551	[173]	[233]	6	hSpCas9	negative selection	11545846
65957573	65957596	15	-	28162770	MOLM13	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	0.329284143315072	[392]	[356]	2	hSpCas9	negative selection	11545847
65922444	65922467	15	+	28162770	MOLM13	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	-0.00878718352665081	[262]	[188]	0	hSpCas9	negative selection	11545848
65922350	65922373	15	+	28162770	MOLM13	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	-1.3456974942245399	[115]	[32]	-6	hSpCas9	negative selection	11545849
65982321	65982344	15	+	28162770	HEL	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	-0.626077926427443	[199]	[82]	-4	hSpCas9	negative selection	11715206
65916838	65916861	15	+	28162770	HEL	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	-0.12652725406915905	[270]	[158]	-1	hSpCas9	negative selection	11715207
66119135	66119158	15	-	28162770	HEL	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	-0.6668291155393993	[522]	[210]	-4	hSpCas9	negative selection	11715208
65982370	65982393	15	+	28162770	HEL	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	-0.18807506288123607	[216]	[121]	-1	hSpCas9	negative selection	11715209
65982332	65982355	15	-	28162770	HEL	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	-1.2958606233355	[298]	[77]	-6	hSpCas9	negative selection	11715210
65964966	65964989	15	-	28162770	HEL	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	0.43791904011185867	[135]	[117]	3	hSpCas9	negative selection	11715211
65957648	65957671	15	+	28162770	HEL	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	-0.9323758827644522	[145]	[48]	-5	hSpCas9	negative selection	11715212
65957573	65957596	15	-	28162770	HEL	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	-1.2317302859157844	[285]	[77]	-6	hSpCas9	negative selection	11715213
65922444	65922467	15	+	28162770	HEL	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	-0.8808231240566561	[229]	[79]	-5	hSpCas9	negative selection	11715214
65922350	65922373	15	+	28162770	HEL	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	-0.08263878789063728	[123]	[74]	0	hSpCas9	negative selection	11715215
65982321	65982344	15	+	28162770	MV411	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	0.5369441679777602	[152]	[186]	5	hSpCas9	negative selection	11884572
65916838	65916861	15	+	28162770	MV411	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	0.13761427283002386	[190]	[176]	1	hSpCas9	negative selection	11884573
66119135	66119158	15	-	28162770	MV411	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.03610879594368743	[432]	[373]	0	hSpCas9	negative selection	11884574
65982370	65982393	15	+	28162770	MV411	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	0.3743496632649949	[173]	[189]	3	hSpCas9	negative selection	11884575
65982332	65982355	15	-	28162770	MV411	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	0.9597410907147121	[176]	[289]	8	hSpCas9	negative selection	11884576
65964966	65964989	15	-	28162770	MV411	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	-0.074490544104587	[149]	[119]	0	hSpCas9	negative selection	11884577
65957648	65957671	15	+	28162770	MV411	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	0.5486070855033403	[111]	[137]	5	hSpCas9	negative selection	11884578
65957573	65957596	15	-	28162770	MV411	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	-0.6046290200812217	[212]	[117]	-4	hSpCas9	negative selection	11884579
65922444	65922467	15	+	28162770	MV411	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	-0.2889447694933192	[218]	[150]	-2	hSpCas9	negative selection	11884580
65922350	65922373	15	+	28162770	MV411	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	1.5597154756364184	[59]	[148]	9	hSpCas9	negative selection	11884581
65982321	65982344	15	+	28162770	MONOMAC1	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	0.6122076561992686	[108]	[190]	6	hSpCas9	negative selection	12053938
65916838	65916861	15	+	28162770	MONOMAC1	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	-0.16198989996035296	[121]	[124]	-1	hSpCas9	negative selection	12053939
66119135	66119158	15	-	28162770	MONOMAC1	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.5576443347544908	[258]	[436]	5	hSpCas9	negative selection	12053940
65982370	65982393	15	+	28162770	MONOMAC1	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	0.15506939649283338	[122]	[156]	1	hSpCas9	negative selection	12053941
65982332	65982355	15	-	28162770	MONOMAC1	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	-0.2979657559103346	[147]	[137]	-3	hSpCas9	negative selection	12053942
65964966	65964989	15	-	28162770	MONOMAC1	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	-0.5700802576737704	[78]	[60]	-5	hSpCas9	negative selection	12053943
65957648	65957671	15	+	28162770	MONOMAC1	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	-0.2536203754259212	[103]	[99]	-2	hSpCas9	negative selection	12053944
65957573	65957596	15	-	28162770	MONOMAC1	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	0.18273532240009305	[175]	[228]	1	hSpCas9	negative selection	12053945
65922444	65922467	15	+	28162770	MONOMAC1	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	0.4753884949119419	[127]	[203]	5	hSpCas9	negative selection	12053946
65922350	65922373	15	+	28162770	MONOMAC1	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	-1.1653279873322153	[44]	[22]	-7	hSpCas9	negative selection	12053947
65982321	65982344	15	+	28162770	OCIAML2	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	0.20975224055767752	[38]	[249]	2	hSpCas9	negative selection	12223304
65916838	65916861	15	+	28162770	OCIAML2	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	-0.5393425753261756	[42]	[163]	-4	hSpCas9	negative selection	12223305
66119135	66119158	15	-	28162770	OCIAML2	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	-0.21655881759993068	[73]	[352]	-2	hSpCas9	negative selection	12223306
65982370	65982393	15	+	28162770	OCIAML2	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	0.42245497084132694	[20]	[155]	4	hSpCas9	negative selection	12223307
65982332	65982355	15	-	28162770	OCIAML2	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	0.638994665932337	[37]	[327]	6	hSpCas9	negative selection	12223308
65964966	65964989	15	-	28162770	OCIAML2	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	1.1016216237294412	[18]	[225]	9	hSpCas9	negative selection	12223309
65957648	65957671	15	+	28162770	OCIAML2	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	0.8692201776424635	[23]	[242]	8	hSpCas9	negative selection	12223310
65957573	65957596	15	-	28162770	OCIAML2	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	-0.45780578488457757	[55]	[225]	-4	hSpCas9	negative selection	12223311
65922444	65922467	15	+	28162770	OCIAML2	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	-0.029031499692182293	[36]	[200]	0	hSpCas9	negative selection	12223312
65922350	65922373	15	+	28162770	OCIAML2	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	0.12693271225862857	[18]	[114]	1	hSpCas9	negative selection	12223313
65982321	65982344	15	+	28162770	OCIAML3	viability	GCAGCTGGCATCCCTTGCCGTGG	MEGF11	ENSG00000157890	-0.5521874646295362	[50]	[104]	-4	hSpCas9	negative selection	12392670
65916838	65916861	15	+	28162770	OCIAML3	viability	GAAGAGTCCAGTCCAGCCAGGGG	MEGF11	ENSG00000157890	-0.1760168236559718	[60]	[162]	-1	hSpCas9	negative selection	12392671
66119135	66119158	15	-	28162770	OCIAML3	viability	GCCTCCGGACCATGTACCGGCGG	MEGF11	ENSG00000157890	0.5804047521104627	[106]	[482]	5	hSpCas9	negative selection	12392672
65982370	65982393	15	+	28162770	OCIAML3	viability	GCGCCATCCACGGAAGCCGGCGG	MEGF11	ENSG00000157890	0.9599279647763685	[46]	[275]	8	hSpCas9	negative selection	12392673
65982332	65982355	15	-	28162770	OCIAML3	viability	GCACCTGGCACCCACGGCAAGGG	MEGF11	ENSG00000157890	-0.29361270698644204	[53]	[132]	-2	hSpCas9	negative selection	12392674
65964966	65964989	15	-	28162770	OCIAML3	viability	CCAGGAGCGACTGTGCCCGGAGG	MEGF11	ENSG00000157890	0.1569648118359222	[40]	[137]	1	hSpCas9	negative selection	12392675
65957648	65957671	15	+	28162770	OCIAML3	viability	CAGGGCAGGATTCATTGCAGTGG	MEGF11	ENSG00000157890	0.5553699837140634	[54]	[243]	5	hSpCas9	negative selection	12392676
65957573	65957596	15	-	28162770	OCIAML3	viability	CGACTGCCACAGCATCACTGGGG	MEGF11	ENSG00000157890	2.0089887832272546	[52]	[643]	9	hSpCas9	negative selection	12392677
65922444	65922467	15	+	28162770	OCIAML3	viability	GCCGTGGCCATAGAACCCAGGGG	MEGF11	ENSG00000157890	-0.46394709975979026	[52]	[115]	-4	hSpCas9	negative selection	12392678
65922350	65922373	15	+	28162770	OCIAML3	viability	GAGCTCCAGAGAATCCTGGGAGG	MEGF11	ENSG00000157890	-0.1651643415202888	[12]	[34]	-1	hSpCas9	negative selection	12392679