Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4225
• Symbol:MEP1B
• Description:meprin A subunit beta

DataSource: http://genomecrispr.dkfz.de/#!/results/MEP1B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
32217080	32217103	18	+	26472758	Jiyoye	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.25714993750126597	[161]	[145]	2	hSpCas9	negative selection	98607
32217763	32217786	18	+	26472758	Jiyoye	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	0.7890460168495179	[65]	[85]	5	hSpCas9	negative selection	98608
32204275	32204298	18	-	26472758	Jiyoye	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.6735687994295819	[142]	[171]	5	hSpCas9	negative selection	98609
32208191	32208214	18	+	26472758	Jiyoye	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	0.5346651166277893	[183]	[200]	4	hSpCas9	negative selection	98610
32208211	32208234	18	+	26472758	Jiyoye	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	1.6464663274156899	[96]	[228]	8	hSpCas9	negative selection	98611
32210569	32210592	18	+	26472758	Jiyoye	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.9666027901198921	[94]	[139]	6	hSpCas9	negative selection	98612
32213178	32213201	18	+	26472758	Jiyoye	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.568456288538934	[185]	[207]	4	hSpCas9	negative selection	98613
32215144	32215167	18	+	26472758	Jiyoye	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	-0.30585215800357723	[258]	[157]	-2	hSpCas9	negative selection	98614
32217033	32217056	18	-	26472758	Jiyoye	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.3786998131412792	[99]	[57]	-3	hSpCas9	negative selection	98615
32217096	32217119	18	+	26472758	Jiyoye	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	-1.177787119215283	[23]	[7]	-7	hSpCas9	negative selection	98616
32217080	32217103	18	+	26472758	KBM7	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.16904361607154253	[611,350]	[253,243]	1	hSpCas9	negative selection	289725
32217763	32217786	18	+	26472758	KBM7	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	-0.0890808076008795	[440,326]	[120,209]	-1	hSpCas9	negative selection	289726
32204275	32204298	18	-	26472758	KBM7	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.1216547877167166	[623,280]	[324,132]	1	hSpCas9	negative selection	289727
32208191	32208214	18	+	26472758	KBM7	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	0.08266765608979842	[1034,647]	[454,371]	0	hSpCas9	negative selection	289728
32208211	32208234	18	+	26472758	KBM7	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.9630748989667172	[701,347]	[561,381]	9	hSpCas9	negative selection	289729
32210569	32210592	18	+	26472758	KBM7	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.1579659705050088	[456,427]	[279,189]	1	hSpCas9	negative selection	289730
32213178	32213201	18	+	26472758	KBM7	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.08786142564297283	[1126,888]	[441,551]	0	hSpCas9	negative selection	289731
32215144	32215167	18	+	26472758	KBM7	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.5120141227226048	[551,475]	[301,380]	5	hSpCas9	negative selection	289732
32217033	32217056	18	-	26472758	KBM7	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.3206568618428871	[472,379]	[148,168]	-3	hSpCas9	negative selection	289733
32217096	32217119	18	+	26472758	KBM7	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	-0.36362116625633956	[79,92]	[12,48]	-3	hSpCas9	negative selection	289734
32217080	32217103	18	+	26472758	Raji	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.6231840115873601	[234]	[83]	6	hSpCas9	negative selection	480843
32217763	32217786	18	+	26472758	Raji	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	1.4793523127605575	[101]	[65]	9	hSpCas9	negative selection	480844
32204275	32204298	18	-	26472758	Raji	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.9983407760783096	[260]	[120]	8	hSpCas9	negative selection	480845
32208191	32208214	18	+	26472758	Raji	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	1.0193273587084033	[303]	[142]	8	hSpCas9	negative selection	480846
32208211	32208234	18	+	26472758	Raji	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.2686644424066603	[371]	[103]	2	hSpCas9	negative selection	480847
32210569	32210592	18	+	26472758	Raji	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	1.0111682201142964	[185]	[86]	8	hSpCas9	negative selection	480848
32213178	32213201	18	+	26472758	Raji	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.24431918072970782	[461]	[126]	2	hSpCas9	negative selection	480849
32215144	32215167	18	+	26472758	Raji	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.24808239828334122	[409]	[112]	2	hSpCas9	negative selection	480850
32217033	32217056	18	-	26472758	Raji	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	0.2744935212088577	[227]	[63]	2	hSpCas9	negative selection	480851
32217096	32217119	18	+	26472758	Raji	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	-0.3076539639052447	[15]	[2]	-3	hSpCas9	negative selection	480852
32217080	32217103	18	+	26472758	K562	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.5609338414800095	[359]	[205]	-4	hSpCas9	negative selection	671961
32217763	32217786	18	+	26472758	K562	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	0.9574717018883248	[218]	[358]	7	hSpCas9	negative selection	671962
32204275	32204298	18	-	26472758	K562	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.6324891793450212	[404]	[529]	5	hSpCas9	negative selection	671963
32208191	32208214	18	+	26472758	K562	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	0.42786486876237817	[707]	[803]	3	hSpCas9	negative selection	671964
32208211	32208234	18	+	26472758	K562	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.7220558533026928	[450]	[627]	6	hSpCas9	negative selection	671965
32210569	32210592	18	+	26472758	K562	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	-0.14499296393690247	[371]	[283]	-1	hSpCas9	negative selection	671966
32213178	32213201	18	+	26472758	K562	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	-0.07355135365223231	[727]	[583]	0	hSpCas9	negative selection	671967
32215144	32215167	18	+	26472758	K562	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.5158583718287789	[598]	[722]	4	hSpCas9	negative selection	671968
32217033	32217056	18	-	26472758	K562	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.6087398840042819	[335]	[185]	-4	hSpCas9	negative selection	671969
32217096	32217119	18	+	26472758	K562	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	-0.6035781788885028	[71]	[39]	-4	hSpCas9	negative selection	671970
32192647	32192670	18	+	26627737	DLD1	viability	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.6817977010157661	[385]	[141,124,294]	6	hSpCas9	negative selection	801362
32204299	32204322	18	+	26627737	DLD1	viability	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.19502059337317323	[644]	[219,104,196]	-2	hSpCas9	negative selection	801363
32207400	32207423	18	+	26627737	DLD1	viability	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	-0.12371491200587253	[508]	[98,210,132]	-1	hSpCas9	negative selection	801364
32208237	32208260	18	+	26627737	DLD1	viability	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.12244210667735977	[1134]	[330,334,313]	-1	hSpCas9	negative selection	801365
32213122	32213145	18	-	26627737	DLD1	viability	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.21448872412164666	[284]	[94,112,30]	-2	hSpCas9	negative selection	801366
32217080	32217103	18	+	26627737	DLD1	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	1.056874268585754	[138]	[100,115,59]	8	hSpCas9	negative selection	801367
32192647	32192670	18	+	26627737	GBM cells	viability after 5 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	-0.07800251200127321	[247]	[103,147]	-1	hSpCas9	negative selection	883677
32204299	32204322	18	+	26627737	GBM cells	viability after 5 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.09215300034430651	[321]	[203,119]	-1	hSpCas9	negative selection	883678
32207400	32207423	18	+	26627737	GBM cells	viability after 5 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.13547606935828843	[274]	[186,136]	2	hSpCas9	negative selection	883679
32208237	32208260	18	+	26627737	GBM cells	viability after 5 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	0.36213110325447234	[345]	[207,268]	5	hSpCas9	negative selection	883680
32213122	32213145	18	-	26627737	GBM cells	viability after 5 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.13071129422359268	[245]	[129,110]	-2	hSpCas9	negative selection	883681
32217080	32217103	18	+	26627737	GBM cells	viability after 5 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.19978035424521856	[137]	[93,75]	3	hSpCas9	negative selection	883682
32192647	32192670	18	+	26627737	GBM cells	viability after 13 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	-0.10911214949395874	[247]	[121,126]	-1	hSpCas9	negative selection	965992
32204299	32204322	18	+	26627737	GBM cells	viability after 13 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.27014890352969767	[321]	[247,60]	-3	hSpCas9	negative selection	965993
32207400	32207423	18	+	26627737	GBM cells	viability after 13 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.4281771730149516	[274]	[213,189]	5	hSpCas9	negative selection	965994
32208237	32208260	18	+	26627737	GBM cells	viability after 13 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	0.784572038433714	[345]	[329,317]	8	hSpCas9	negative selection	965995
32213122	32213145	18	-	26627737	GBM cells	viability after 13 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	0.11208966436417106	[245]	[178,115]	1	hSpCas9	negative selection	965996
32217080	32217103	18	+	26627737	GBM cells	viability after 13 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.2850987965860301	[137]	[152,40]	3	hSpCas9	negative selection	965997
32192647	32192670	18	+	26627737	GBM cells	viability after 21 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.5579011676906512	[247]	[201,194]	5	hSpCas9	negative selection	1048307
32204299	32204322	18	+	26627737	GBM cells	viability after 21 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.8942201006701589	[321]	[102,85]	-6	hSpCas9	negative selection	1048308
32207400	32207423	18	+	26627737	GBM cells	viability after 21 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.5392352417297094	[274]	[237,197]	5	hSpCas9	negative selection	1048309
32208237	32208260	18	+	26627737	GBM cells	viability after 21 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	0.7945298992443135	[345]	[324,326]	7	hSpCas9	negative selection	1048310
32213122	32213145	18	-	26627737	GBM cells	viability after 21 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.02836882323134056	[245]	[129,131]	0	hSpCas9	negative selection	1048311
32217080	32217103	18	+	26627737	GBM cells	viability after 21 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.6284455989565989	[137]	[129,102]	6	hSpCas9	negative selection	1048312
32192647	32192670	18	+	26627737	RPE1	viability after 9 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.47258589426091907	[516]	[145,325]	3	hSpCas9	negative selection	1130622
32204299	32204322	18	+	26627737	RPE1	viability after 9 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.8410264855262682	[924]	[179,137]	-6	hSpCas9	negative selection	1130623
32207400	32207423	18	+	26627737	RPE1	viability after 9 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	1.0615284661403082	[638]	[434,394]	6	hSpCas9	negative selection	1130624
32208237	32208260	18	+	26627737	RPE1	viability after 9 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.26622357644781647	[1898]	[289,757]	-2	hSpCas9	negative selection	1130625
32213122	32213145	18	-	26627737	RPE1	viability after 9 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.03545982423374627	[509]	[143,170]	0	hSpCas9	negative selection	1130626
32217080	32217103	18	+	26627737	RPE1	viability after 9 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.021233432471133906	[634]	[230,163]	0	hSpCas9	negative selection	1130627
32192647	32192670	18	+	26627737	RPE1	viability after 12 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.8359547952299793	[516]	[126,375]	5	hSpCas9	negative selection	1212937
32204299	32204322	18	+	26627737	RPE1	viability after 12 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-1.0123396979229973	[924]	[95,151]	-6	hSpCas9	negative selection	1212938
32207400	32207423	18	+	26627737	RPE1	viability after 12 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	1.362848956396581	[638]	[527,349]	7	hSpCas9	negative selection	1212939
32208237	32208260	18	+	26627737	RPE1	viability after 12 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.41683666334044334	[1898]	[285,483]	-3	hSpCas9	negative selection	1212940
32213122	32213145	18	-	26627737	RPE1	viability after 12 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	0.22703130183125347	[509]	[172,146]	1	hSpCas9	negative selection	1212941
32217080	32217103	18	+	26627737	RPE1	viability after 12 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.7743597453786035	[634]	[107,90]	-5	hSpCas9	negative selection	1212942
32192647	32192670	18	+	26627737	RPE1	viability after 15 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	-0.024433447095073002	[516]	[42,240]	0	hSpCas9	negative selection	1295252
32204299	32204322	18	+	26627737	RPE1	viability after 15 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-2.757585809867345	[924]	[55,21]	-9	hSpCas9	negative selection	1295253
32207400	32207423	18	+	26627737	RPE1	viability after 15 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	1.0161436594659767	[638]	[416,315]	6	hSpCas9	negative selection	1295254
32208237	32208260	18	+	26627737	RPE1	viability after 15 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.11719954163850743	[1898]	[479,509]	0	hSpCas9	negative selection	1295255
32213122	32213145	18	-	26627737	RPE1	viability after 15 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.5224625361060784	[509]	[103,96]	-3	hSpCas9	negative selection	1295256
32217080	32217103	18	+	26627737	RPE1	viability after 15 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.5352994807779183	[634]	[126,120]	-3	hSpCas9	negative selection	1295257
32192647	32192670	18	+	26627737	RPE1	viability after 18 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.6341394231744334	[516]	[71,370]	4	hSpCas9	negative selection	1377567
32204299	32204322	18	+	26627737	RPE1	viability after 18 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-1.2564457470713832	[924]	[176,26]	-7	hSpCas9	negative selection	1377568
32207400	32207423	18	+	26627737	RPE1	viability after 18 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	1.2655295665792554	[638]	[591,224]	7	hSpCas9	negative selection	1377569
32208237	32208260	18	+	26627737	RPE1	viability after 18 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.4101039149946475	[1898]	[317,457]	-3	hSpCas9	negative selection	1377570
32213122	32213145	18	-	26627737	RPE1	viability after 18 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	0.1846563229011835	[509]	[95,220]	1	hSpCas9	negative selection	1377571
32217080	32217103	18	+	26627737	RPE1	viability after 18 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.01514530324887986	[634]	[119,229]	0	hSpCas9	negative selection	1377572
32192647	32192670	18	+	26627737	HeLa	viability after 8 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	-0.10905205836697518	[510]	[424,84,159]	-1	hSpCas9	negative selection	1459882
32204299	32204322	18	+	26627737	HeLa	viability after 8 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.8418201391040266	[865]	[217,167,243]	-7	hSpCas9	negative selection	1459883
32207400	32207423	18	+	26627737	HeLa	viability after 8 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.2676294954567242	[405]	[359,105,204]	2	hSpCas9	negative selection	1459884
32208237	32208260	18	+	26627737	HeLa	viability after 8 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.24026534604065997	[910]	[611,184,274]	-2	hSpCas9	negative selection	1459885
32213122	32213145	18	-	26627737	HeLa	viability after 8 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.21285116425621564	[227]	[91,32,129]	-2	hSpCas9	negative selection	1459886
32217080	32217103	18	+	26627737	HeLa	viability after 8 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.27721491038485224	[273]	[158,167,111]	2	hSpCas9	negative selection	1459887
32192647	32192670	18	+	26627737	HeLa	viability after 12 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	-0.17299435405882368	[510]	[92,226,234]	-1	hSpCas9	negative selection	1542197
32204299	32204322	18	+	26627737	HeLa	viability after 12 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.8234729440536441	[865]	[277,106,233]	-6	hSpCas9	negative selection	1542198
32207400	32207423	18	+	26627737	HeLa	viability after 12 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.7256185755471346	[405]	[427,189,227]	6	hSpCas9	negative selection	1542199
32208237	32208260	18	+	26627737	HeLa	viability after 12 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.11134980852790854	[910]	[250,260,539]	-1	hSpCas9	negative selection	1542200
32213122	32213145	18	-	26627737	HeLa	viability after 12 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	0.19411291684561915	[227]	[59,69,195]	1	hSpCas9	negative selection	1542201
32217080	32217103	18	+	26627737	HeLa	viability after 12 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.562070384126721	[273]	[129,44,59]	-5	hSpCas9	negative selection	1542202
32192647	32192670	18	+	26627737	HeLa	viability after 15 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.42154260479283606	[510]	[188,393,251]	3	hSpCas9	negative selection	1624512
32204299	32204322	18	+	26627737	HeLa	viability after 15 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-1.0261616753647251	[865]	[187,62,275]	-7	hSpCas9	negative selection	1624513
32207400	32207423	18	+	26627737	HeLa	viability after 15 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.21820294025081144	[405]	[247,136,190]	1	hSpCas9	negative selection	1624514
32208237	32208260	18	+	26627737	HeLa	viability after 15 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.13939150727141247	[910]	[220,364,432]	-1	hSpCas9	negative selection	1624515
32213122	32213145	18	-	26627737	HeLa	viability after 15 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	0.3343129659623578	[227]	[154,145,43]	3	hSpCas9	negative selection	1624516
32217080	32217103	18	+	26627737	HeLa	viability after 15 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.8223941273461395	[273]	[61,30,98]	-6	hSpCas9	negative selection	1624517
32192647	32192670	18	+	26627737	HeLa	viability after 18 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.39682482064094854	[510]	[120,321,251]	3	hSpCas9	negative selection	1706827
32204299	32204322	18	+	26627737	HeLa	viability after 18 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.9909242888396061	[865]	[132,53,275]	-7	hSpCas9	negative selection	1706828
32207400	32207423	18	+	26627737	HeLa	viability after 18 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.27807812343454374	[405]	[184,109,190]	2	hSpCas9	negative selection	1706829
32208237	32208260	18	+	26627737	HeLa	viability after 18 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.13426237950423348	[910]	[157,292,432]	-1	hSpCas9	negative selection	1706830
32213122	32213145	18	-	26627737	HeLa	viability after 18 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	0.34873297887253873	[227]	[102,124,43]	3	hSpCas9	negative selection	1706831
32217080	32217103	18	+	26627737	HeLa	viability after 18 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.8334302712300505	[273]	[41,23,98]	-6	hSpCas9	negative selection	1706832
32192647	32192670	18	+	26627737	HCT116	viability after 6 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.28771253126236046	[715]	[119,146]	1	hSpCas9	negative selection	1789142
32204299	32204322	18	+	26627737	HCT116	viability after 6 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-1.8123073391970892	[1033]	[73,30]	-8	hSpCas9	negative selection	1789143
32207400	32207423	18	+	26627737	HCT116	viability after 6 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	-0.8410377775099916	[693]	[96,40]	-5	hSpCas9	negative selection	1789144
32208237	32208260	18	+	26627737	HCT116	viability after 6 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	0.7055227882795505	[765]	[488,34]	4	hSpCas9	negative selection	1789145
32213122	32213145	18	-	26627737	HCT116	viability after 6 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.47607536764492653	[707]	[99,68]	-3	hSpCas9	negative selection	1789146
32217080	32217103	18	+	26627737	HCT116	viability after 6 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-2.986852522251084	[585]	[19,6]	-9	hSpCas9	negative selection	1789147
32192647	32192670	18	+	26627737	HCT116	viability after 8 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.37348762661502233	[320]	[197,269,218]	4	hSpCas9	negative selection	1871457
32204299	32204322	18	+	26627737	HCT116	viability after 8 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.7128710317800349	[601]	[243,252,111]	-7	hSpCas9	negative selection	1871458
32207400	32207423	18	+	26627737	HCT116	viability after 8 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.808439518961585	[205]	[205,231,158]	7	hSpCas9	negative selection	1871459
32208237	32208260	18	+	26627737	HCT116	viability after 8 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	0.7286748978395197	[391]	[370,422,280]	7	hSpCas9	negative selection	1871460
32213122	32213145	18	-	26627737	HCT116	viability after 8 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	0.021039791823022652	[325]	[220,101,223]	0	hSpCas9	negative selection	1871461
32217080	32217103	18	+	26627737	HCT116	viability after 8 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.6202882548363811	[246]	[87,120,56]	-6	hSpCas9	negative selection	1871462
32192647	32192670	18	+	26627737	HCT116	viability after 9 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.805889734134634	[715]	[207,433]	6	hSpCas9	negative selection	1953772
32204299	32204322	18	+	26627737	HCT116	viability after 9 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	0.33510749178702604	[1033]	[149,504]	2	hSpCas9	negative selection	1953773
32207400	32207423	18	+	26627737	HCT116	viability after 9 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.2059025592209359	[693]	[282,158]	1	hSpCas9	negative selection	1953774
32208237	32208260	18	+	26627737	HCT116	viability after 9 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	0.7081549070876143	[765]	[346,323]	5	hSpCas9	negative selection	1953775
32213122	32213145	18	-	26627737	HCT116	viability after 9 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	0.34319134571961935	[707]	[169,294]	2	hSpCas9	negative selection	1953776
32217080	32217103	18	+	26627737	HCT116	viability after 9 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.8157871158623268	[585]	[46,121]	-5	hSpCas9	negative selection	1953777
32192647	32192670	18	+	26627737	HCT116	viability after 12 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.5082563051566032	[320]	[328,198,182]	5	hSpCas9	negative selection	2036087
32204299	32204322	18	+	26627737	HCT116	viability after 12 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.7078849590659233	[601]	[215,230,132]	-6	hSpCas9	negative selection	2036088
32207400	32207423	18	+	26627737	HCT116	viability after 12 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	1.0298853224289881	[205]	[199,179,283]	8	hSpCas9	negative selection	2036089
32208237	32208260	18	+	26627737	HCT116	viability after 12 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	0.8209035853263786	[391]	[387,296,402]	7	hSpCas9	negative selection	2036090
32213122	32213145	18	-	26627737	HCT116	viability after 12 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.42531897540842006	[325]	[119,110,151]	-4	hSpCas9	negative selection	2036091
32217080	32217103	18	+	26627737	HCT116	viability after 12 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.6231060681867099	[246]	[101,113,35]	-6	hSpCas9	negative selection	2036092
32192647	32192670	18	+	26627737	HCT116	viability after 15 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	-0.2408243787402531	[320]	[235,105,135]	-2	hSpCas9	negative selection	2118402
32204299	32204322	18	+	26627737	HCT116	viability after 15 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.4600232682719039	[601]	[253,304,195]	-5	hSpCas9	negative selection	2118403
32207400	32207423	18	+	26627737	HCT116	viability after 15 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.21022901278105321	[205]	[118,117,170]	2	hSpCas9	negative selection	2118404
32208237	32208260	18	+	26627737	HCT116	viability after 15 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	1.0332349953306907	[391]	[474,451,456]	8	hSpCas9	negative selection	2118405
32213122	32213145	18	-	26627737	HCT116	viability after 15 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.3788087938318021	[325]	[220,48,170]	-4	hSpCas9	negative selection	2118406
32217080	32217103	18	+	26627737	HCT116	viability after 15 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.4021402096333041	[246]	[125,65,131]	-4	hSpCas9	negative selection	2118407
32192647	32192670	18	+	26627737	HCT116	viability after 18 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.379774189885124	[320]	[347,79,184]	3	hSpCas9	negative selection	2200717
32204299	32204322	18	+	26627737	HCT116	viability after 18 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.7323146464167187	[601]	[183,124,221]	-6	hSpCas9	negative selection	2200718
32207400	32207423	18	+	26627737	HCT116	viability after 18 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.9086133015013782	[205]	[234,148,178]	7	hSpCas9	negative selection	2200719
32208237	32208260	18	+	26627737	HCT116	viability after 18 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	1.6051584604411877	[391]	[807,452,471]	9	hSpCas9	negative selection	2200720
32213122	32213145	18	-	26627737	HCT116	viability after 18 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.9686082995502208	[325]	[94,36,113]	-7	hSpCas9	negative selection	2200721
32217080	32217103	18	+	26627737	HCT116	viability after 18 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.5915814448743737	[246]	[120,16,104]	-5	hSpCas9	negative selection	2200722
32189911	32189934	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGGACTTTCATCCCTTGATTGG	MEP1B	ENSG00000141434	-0.04524618152259885	[184,252]	[17,76]	0	dCas9-VP64	positive selection	2438863
32189889	32189912	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTATTTTTAACACAGCTCTGCGG	MEP1B	ENSG00000141434	0.8384039855985965	[76,34]	[19,23]	3	dCas9-VP64	positive selection	2438864
32189835	32189858	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGTCAACAATTAAGTGCCTGG	MEP1B	ENSG00000141434	2.3645778231348924	[67,66]	[5,152]	7	dCas9-VP64	positive selection	2438865
32189911	32189934	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGGACTTTCATCCCTTGATTGG	MEP1B	ENSG00000141434	-0.24218744307131312	[429,221]	[93,86]	-2	dCas9-VP64	positive selection	2534118
32189889	32189912	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTATTTTTAACACAGCTCTGCGG	MEP1B	ENSG00000141434	-0.5378380936224954	[29,127]	[10,22]	-5	dCas9-VP64	positive selection	2534119
32189835	32189858	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGTCAACAATTAAGTGCCTGG	MEP1B	ENSG00000141434	0.7217578916091157	[91,64]	[21,60]	5	dCas9-VP64	positive selection	2534120
32202983	32203006	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACTATATATCAGTGTTCAAGGG	MEP1B	ENSG00000141434	0.07530287802829223	[3,3]	[3,1]	1	hSpCas9	positive selection	3001984
32204188	32204211	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCTTCAGTAGGAAATAGGCGG	MEP1B	ENSG00000141434	0.49937252045265607	[2,3]	[4,2]	8	hSpCas9	positive selection	3001985
32204178	32204201	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAAGCTGCTGGTCTTCAGTAGG	MEP1B	ENSG00000141434	0.19630136901373652	[3,3]	[3,4]	4	hSpCas9	positive selection	3001986
32195465	32195488	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATGTTCTAGAAGATAGCTTGGG	MEP1B	ENSG00000141434	0.41241478145693533	[3,4]	[4,5]	8	hSpCas9	positive selection	3001987
32202983	32203006	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACTATATATCAGTGTTCAAGGG	MEP1B	ENSG00000141434	-0.46071642537590507	[3,3]	[3,0]	-6	hSpCas9	positive selection	3069842
32204188	32204211	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCTTCAGTAGGAAATAGGCGG	MEP1B	ENSG00000141434	0.6174723779371853	[2,2]	[2,2]	8	hSpCas9	positive selection	3069843
32204178	32204201	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAAGCTGCTGGTCTTCAGTAGG	MEP1B	ENSG00000141434	0.42395605719293145	[3,3]	[3,3]	7	hSpCas9	positive selection	3069844
32195465	32195488	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATGTTCTAGAAGATAGCTTGGG	MEP1B	ENSG00000141434	0.5522905089871173	[3,3]	[5,3]	8	hSpCas9	positive selection	3069845
32191828	32191851		-	24336571	A375	resistance to PLX after 7 days	ATAGACTCACCAAAGTTTTCTGG	MEP1B	ENSG00000141434	-0.2448175461641613	[3,2]	[2,2]	-7	hSpCas9	positive selection	3127147
32191819	32191842		+	24336571	A375	resistance to PLX after 7 days	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.005963122949162125	[4,6]	[5,5]	0	hSpCas9	positive selection	3127149
32192665	32192688		-	24336571	A375	resistance to PLX after 7 days	CATTGATATCAAATATGTCCTGG	MEP1B	ENSG00000141434	-0.13508938173825785	[9,7]	[7,8]	-4	hSpCas9	positive selection	3127150
32192636	32192659		+	24336571	A375	resistance to PLX after 7 days	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.07045032788842859	[9,8]	[10,8]	2	hSpCas9	positive selection	3127151
32191828	32191851		-	24336571	A375	resistance to PLX after 14 days	ATAGACTCACCAAAGTTTTCTGG	MEP1B	ENSG00000141434	0.20514938876771716	[5,2]	[1,1]	2	hSpCas9	positive selection	3184940
32191819	32191842		+	24336571	A375	resistance to PLX after 14 days	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.49469735495081224	[7,6]	[1,1]	-6	hSpCas9	positive selection	3184942
32192665	32192688		-	24336571	A375	resistance to PLX after 14 days	CATTGATATCAAATATGTCCTGG	MEP1B	ENSG00000141434	0.08040474634951805	[12,5]	[3,4]	0	hSpCas9	positive selection	3184943
32192636	32192659		+	24336571	A375	resistance to PLX after 14 days	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.28243352504817776	[8,9]	[2,3]	-3	hSpCas9	positive selection	3184944
32191828	32191851		-	24336571	A375	viability after 7 days	ATAGACTCACCAAAGTTTTCTGG	MEP1B	ENSG00000141434	0.6966074192795417	[1]	[3,2]	9	hSpCas9	negative selection	3242733
32191819	32191842		+	24336571	A375	viability after 7 days	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	0.014136010388924758	[5]	[4,6]	0	hSpCas9	negative selection	3242735
32192665	32192688		-	24336571	A375	viability after 7 days	CATTGATATCAAATATGTCCTGG	MEP1B	ENSG00000141434	-1.1096601584386128	[21]	[9,7]	-9	hSpCas9	negative selection	3242736
32192636	32192659		+	24336571	A375	viability after 7 days	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.00984820479037829	[9]	[9,8]	0	hSpCas9	negative selection	3242737
32191828	32191851		-	24336571	A375	viability after 14 days	ATAGACTCACCAAAGTTTTCTGG	MEP1B	ENSG00000141434	1.0027330649094373	[1]	[5,2]	9	hSpCas9	negative selection	3300526
32191819	32191842		+	24336571	A375	viability after 14 days	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	0.3635254369044225	[5]	[7,6]	5	hSpCas9	negative selection	3300528
32192665	32192688		-	24336571	A375	viability after 14 days	CATTGATATCAAATATGTCCTGG	MEP1B	ENSG00000141434	-1.06974900096837	[21]	[12,5]	-8	hSpCas9	negative selection	3300529
32192636	32192659		+	24336571	A375	viability after 14 days	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.11568428029604277	[9]	[8,9]	1	hSpCas9	negative selection	3300530
32191819	32191842	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	1.5024387092823666	[53,53]	[0,0]	6	hSpCas9	positive selection	3379038
32192669	32192692	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.851198245332334	[275,275]	[0,0]	-6	hSpCas9	positive selection	3379039
32195463	32195486	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.7027373597681978	[93,93]	[0,0]	3	hSpCas9	positive selection	3379040
32202982	32203005	18	+	26780180	HT29	viability (Avana library 4 designs)	AACTATATATCAGTGTTCAAGGG	MEP1B	ENSG00000141434	0.65941442252729	[]	[]	2	hSpCas9	negative selection	3439718
32204187	32204210	18	+	26780180	HT29	viability (Avana library 4 designs)	GGTCTTCAGTAGGAAATAGGCGG	MEP1B	ENSG00000141434	1.50044648175128	[]	[]	6	hSpCas9	negative selection	3439719
32204177	32204200	18	+	26780180	HT29	viability (Avana library 4 designs)	GTAAGCTGCTGGTCTTCAGTAGG	MEP1B	ENSG00000141434	0.444530192488631	[]	[]	1	hSpCas9	negative selection	3439720
32195464	32195487	18	+	26780180	HT29	viability (Avana library 4 designs)	TATGTTCTAGAAGATAGCTTGGG	MEP1B	ENSG00000141434	0.622813620412949	[]	[]	2	hSpCas9	negative selection	3439721
32195464	32195487	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATGTTCTAGAAGATAGCTTGGG	MEP1B	ENSG00000141434	-10.3356610719633	[]	[]	-8	hSpCas9	negative selection	3529599
32204177	32204200	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAAGCTGCTGGTCTTCAGTAGG	MEP1B	ENSG00000141434	5.21856993044076	[]	[]	8	hSpCas9	negative selection	3529600
32202982	32203005	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	AACTATATATCAGTGTTCAAGGG	MEP1B	ENSG00000141434	-13.4636400458959	[]	[]	-8	hSpCas9	negative selection	3529601
32204187	32204210	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCTTCAGTAGGAAATAGGCGG	MEP1B	ENSG00000141434	-0.744545467823122	[]	[]	-1	hSpCas9	negative selection	3529602
32204275	32204298	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	3.2997990729565	[]	[]	5	hSpCas9	negative selection	3529603
32207297	32207320	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAATCATAGGGAACATTCAGGG	MEP1B	ENSG00000141434	-5.80756537692753	[]	[]	-6	hSpCas9	negative selection	3529604
32195464	32195487	18	+	26780180	A375	viability (Avana lentiGuide)	TATGTTCTAGAAGATAGCTTGGG	MEP1B	ENSG00000141434	2.14082623645157	[]	[]	2	hSpCas9	negative selection	3638258
32204177	32204200	18	+	26780180	A375	viability (Avana lentiGuide)	GTAAGCTGCTGGTCTTCAGTAGG	MEP1B	ENSG00000141434	1.01756732633519	[]	[]	1	hSpCas9	negative selection	3638259
32202982	32203005	18	+	26780180	A375	viability (Avana lentiGuide)	AACTATATATCAGTGTTCAAGGG	MEP1B	ENSG00000141434	-3.99903244755916	[]	[]	-7	hSpCas9	negative selection	3638260
32204187	32204210	18	+	26780180	A375	viability (Avana lentiGuide)	GGTCTTCAGTAGGAAATAGGCGG	MEP1B	ENSG00000141434	-1.10980552966738	[]	[]	-2	hSpCas9	negative selection	3638261
32204275	32204298	18	-	26780180	A375	viability (Avana lentiGuide)	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	-1.64776862866887	[]	[]	-3	hSpCas9	negative selection	3638262
32207297	32207320	18	-	26780180	A375	viability (Avana lentiGuide)	GTAATCATAGGGAACATTCAGGG	MEP1B	ENSG00000141434	-7.27500077498863	[]	[]	-9	hSpCas9	negative selection	3638263
32195464	32195487	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATGTTCTAGAAGATAGCTTGGG	MEP1B	ENSG00000141434	-0.6689970882523602	[8]	[4,5]	-7	hSpCas9	positive selection	3746917
32204177	32204200	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAAGCTGCTGGTCTTCAGTAGG	MEP1B	ENSG00000141434	0.3692658982003436	[5]	[6,6]	9	hSpCas9	positive selection	3746918
32202982	32203005	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACTATATATCAGTGTTCAAGGG	MEP1B	ENSG00000141434	-0.879002476085154	[9]	[5,3]	-8	hSpCas9	positive selection	3746919
32204187	32204210	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCTTCAGTAGGAAATAGGCGG	MEP1B	ENSG00000141434	-0.7424632252123661	[4]	[3,1]	-8	hSpCas9	positive selection	3746920
32204275	32204298	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.26338364763113875	[5]	[6,6]	7	hSpCas9	positive selection	3746921
32207297	32207320	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAATCATAGGGAACATTCAGGG	MEP1B	ENSG00000141434	-0.30298715537857446	[6]	[4,5]	-4	hSpCas9	positive selection	3746922
32195464	32195487	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATGTTCTAGAAGATAGCTTGGG	MEP1B	ENSG00000141434	0.15495568644347002	[6]	[5,6]	3	hSpCas9	positive selection	3855524
32204177	32204200	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAAGCTGCTGGTCTTCAGTAGG	MEP1B	ENSG00000141434	-0.20594125453142043	[5]	[4,3]	-3	hSpCas9	positive selection	3855525
32202982	32203005	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACTATATATCAGTGTTCAAGGG	MEP1B	ENSG00000141434	-0.45615724743756675	[4]	[1,3]	-5	hSpCas9	positive selection	3855526
32204187	32204210	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCTTCAGTAGGAAATAGGCGG	MEP1B	ENSG00000141434	-0.08495675828711974	[4]	[3,3]	-1	hSpCas9	positive selection	3855527
32204275	32204298	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.2097112570325864	[6]	[5,6]	5	hSpCas9	positive selection	3855528
32207297	32207320	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAATCATAGGGAACATTCAGGG	MEP1B	ENSG00000141434	0.5025211747007678	[4]	[6,5]	9	hSpCas9	positive selection	3855529
32192795	32192818	18	+	26780180	A375	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	1.33574915246872	[]	[]	7	hSpCas9	negative selection	3961007
32195463	32195486	18	+	26780180	A375	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	1.11975977102068	[]	[]	5	hSpCas9	negative selection	3961008
32191819	32191842	18	+	26780180	A375	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	1.03550147144832	[]	[]	5	hSpCas9	negative selection	3961009
32192669	32192692	18	+	26780180	A375	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	0.810724349839138	[]	[]	3	hSpCas9	negative selection	3961010
32192636	32192659	18	+	26780180	A375	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.638805111236517	[]	[]	2	hSpCas9	negative selection	3961011
32192763	32192786	18	+	26780180	A375	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.622170094301964	[]	[]	2	hSpCas9	negative selection	3961012
32192795	32192818	18	+	26780180	HT29	viability (GeCKOv2 library)	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	1.35017259457386	[]	[]	7	hSpCas9	negative selection	4068973
32195463	32195486	18	+	26780180	HT29	viability (GeCKOv2 library)	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.886194199825919	[]	[]	4	hSpCas9	negative selection	4068974
32191819	32191842	18	+	26780180	HT29	viability (GeCKOv2 library)	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	1.53856796836602	[]	[]	7	hSpCas9	negative selection	4068975
32192669	32192692	18	+	26780180	HT29	viability (GeCKOv2 library)	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	0.704247346651491	[]	[]	2	hSpCas9	negative selection	4068976
32192636	32192659	18	+	26780180	HT29	viability (GeCKOv2 library)	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	1.34872776427918	[]	[]	7	hSpCas9	negative selection	4068977
32192763	32192786	18	+	26780180	HT29	viability (GeCKOv2 library)	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.113803841663213	[]	[]	0	hSpCas9	negative selection	4068978
32191828	32191851	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATAGACTCACCAAAGTTTTCTGG	MEP1B	ENSG00000141434	-0.04618011749699136	[2]	[1,0]	-1	hSpCas9	positive selection	4151462
32191819	32191842	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.06043549045817059	[2]	[1,0]	-1	hSpCas9	positive selection	4151464
32192665	32192688	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATTGATATCAAATATGTCCTGG	MEP1B	ENSG00000141434	0.007987224775137414	[3]	[1,1]	0	hSpCas9	positive selection	4151465
32192636	32192659	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.07601420958103938	[2]	[0,1]	-2	hSpCas9	positive selection	4151466
32191828	32191851	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATAGACTCACCAAAGTTTTCTGG	MEP1B	ENSG00000141434	0.6691819052703775	[1]	[2,0,0,0]	4	hSpCas9	positive selection	4215484
32191819	32191842	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	0.37040156427892534	[2]	[5,0,1,0]	2	hSpCas9	positive selection	4215486
32192665	32192688	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATTGATATCAAATATGTCCTGG	MEP1B	ENSG00000141434	0.09984770919872453	[3]	[2,3,1,0]	0	hSpCas9	positive selection	4215487
32192636	32192659	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.21319444959483413	[3]	[0,4,0,0]	-3	hSpCas9	positive selection	4215488
32192795	32192818	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.1701643345611975	[2]	[2,1]	3	hSpCas9	positive selection	4282557
32192636	32192659	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.18607685394125012	[2]	[1,0]	-4	hSpCas9	positive selection	4282558
32192763	32192786	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.18228400772736508	[3]	[3,2]	3	hSpCas9	positive selection	4282559
32191819	32191842	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.42426045334188933	[3]	[3,0]	-7	hSpCas9	positive selection	4346815
32192669	32192692	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	0.2519461531146337	[3]	[3,3]	5	hSpCas9	positive selection	4346816
32195463	32195486	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.14200228724773964	[2]	[2,1]	3	hSpCas9	positive selection	4346817
32204229	32204251	18	-	27760321	OCIAML3	viability	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	0.18001465583428056	[1172,989]	[807,1145]	2	hSpCas9	negative selection	4417781
32204299	32204321	18	+	27760321	OCIAML3	viability	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	-0.32955039552954973	[609,484]	[352,319]	-3	hSpCas9	negative selection	4417782
32207401	32207423	18	+	27760321	OCIAML3	viability	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.051738897745087935	[454,370]	[313,357]	0	hSpCas9	negative selection	4417783
32208125	32208147	18	-	27760321	OCIAML3	viability	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	0.8659910439215279	[170,126]	[203,218]	8	hSpCas9	negative selection	4417784
32210570	32210592	18	+	27760321	OCIAML3	viability	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.2320119517297894	[216,156]	[130,220]	2	hSpCas9	negative selection	4417785
32204229	32204251	18	-	27760321	OCIAML2	viability	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	0.24434390174049336	[1172,989]	[887,1222]	3	hSpCas9	negative selection	4501244
32204299	32204321	18	+	27760321	OCIAML2	viability	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	-0.030758500259380595	[609,484]	[420,443]	0	hSpCas9	negative selection	4501245
32207401	32207423	18	+	27760321	OCIAML2	viability	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.5367281769155129	[454,370]	[366,633]	7	hSpCas9	negative selection	4501246
32208125	32208147	18	-	27760321	OCIAML2	viability	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	0.6540795574502521	[170,126]	[187,187]	8	hSpCas9	negative selection	4501247
32210570	32210592	18	+	27760321	OCIAML2	viability	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.2459282462464183	[216,156]	[149,213]	3	hSpCas9	negative selection	4501248
32204229	32204251	18	-	27760321	MV411	viability	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	1.137214946193786	[1172,989]	[1854,1126]	8	hSpCas9	negative selection	4584707
32204299	32204321	18	+	27760321	MV411	viability	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	-0.9099106727119384	[609,484]	[91,339]	-6	hSpCas9	negative selection	4584708
32207401	32207423	18	+	27760321	MV411	viability	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	1.1590767337001588	[454,370]	[529,718]	8	hSpCas9	negative selection	4584709
32208125	32208147	18	-	27760321	MV411	viability	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	1.0461388082035388	[170,126]	[16,477]	7	hSpCas9	negative selection	4584710
32210570	32210592	18	+	27760321	MV411	viability	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.08465397842413402	[216,156]	[87,191]	0	hSpCas9	negative selection	4584711
32204229	32204251	18	-	27760321	HL60	viability	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	-0.022456822986995917	[1172,989]	[820,914]	0	hSpCas9	negative selection	4668170
32204299	32204321	18	+	27760321	HL60	viability	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	-0.5252219055375862	[609,484]	[254,365]	-5	hSpCas9	negative selection	4668171
32207401	32207423	18	+	27760321	HL60	viability	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	1.80471007096539	[454,370]	[912,1447]	9	hSpCas9	negative selection	4668172
32208125	32208147	18	-	27760321	HL60	viability	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	1.1086246521690912	[170,126]	[380,131]	9	hSpCas9	negative selection	4668173
32210570	32210592	18	+	27760321	HL60	viability	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	-0.05006150981652868	[216,156]	[148,142]	0	hSpCas9	negative selection	4668174
32204229	32204251	18	-	27760321	HT1080	viability	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	0.936502699157882	[989,772]	[589,761]	5	hSpCas9	negative selection	4751633
32204299	32204321	18	+	27760321	HT1080	viability	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	0.7375492855274561	[484,378]	[222,356]	4	hSpCas9	negative selection	4751634
32207401	32207423	18	+	27760321	HT1080	viability	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	-0.008632920600568583	[370,289]	[117,144]	0	hSpCas9	negative selection	4751635
32208125	32208147	18	-	27760321	HT1080	viability	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	2.010393421599047	[126,98]	[114,253]	9	hSpCas9	negative selection	4751636
32210570	32210592	18	+	27760321	HT1080	viability	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	1.7869740722853282	[156,122]	[276,99]	8	hSpCas9	negative selection	4751637
32204229	32204251	18	-	27760321	HT29	viability after 7 days	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	0.35387345602382636	[989,772]	[1779,1621,1002]	5	hSpCas9	negative selection	4835096
32204299	32204321	18	+	27760321	HT29	viability after 7 days	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	-0.4595816906050316	[484,378]	[384,243,573]	-6	hSpCas9	negative selection	4835097
32207401	32207423	18	+	27760321	HT29	viability after 7 days	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.22862783770497364	[370,289]	[720,562,248]	3	hSpCas9	negative selection	4835098
32208125	32208147	18	-	27760321	HT29	viability after 7 days	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	0.4793570490436052	[126,98]	[176,234,191]	7	hSpCas9	negative selection	4835099
32210570	32210592	18	+	27760321	HT29	viability after 7 days	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.3008082151834677	[156,122]	[186,280,192]	4	hSpCas9	negative selection	4835100
32204229	32204251	18	-	27760321	HT29	viability after 25 days	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	0.4207215095352752	[989,772]	[1376,1029,1667]	4	hSpCas9	negative selection	4918559
32204299	32204321	18	+	27760321	HT29	viability after 25 days	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	-0.5902829813513459	[484,378]	[397,148,443]	-5	hSpCas9	negative selection	4918560
32207401	32207423	18	+	27760321	HT29	viability after 25 days	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.2711530204136272	[370,289]	[422,316,648]	3	hSpCas9	negative selection	4918561
32208125	32208147	18	-	27760321	HT29	viability after 25 days	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	0.33793729581760457	[126,98]	[116,162,217]	3	hSpCas9	negative selection	4918562
32210570	32210592	18	+	27760321	HT29	viability after 25 days	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.2801993480777287	[156,122]	[198,209,170]	3	hSpCas9	negative selection	4918563
32204229	32204251	18	-	27760321	HT29	viability after 22 days	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	0.18211667775028606	[989,772]	[1216,1188,1059]	1	hSpCas9	negative selection	5002022
32204299	32204321	18	+	27760321	HT29	viability after 22 days	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	-0.004782412003475622	[484,378]	[810,375,295]	0	hSpCas9	negative selection	5002023
32207401	32207423	18	+	27760321	HT29	viability after 22 days	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.8189641147944708	[370,289]	[761,362,896]	8	hSpCas9	negative selection	5002024
32208125	32208147	18	-	27760321	HT29	viability after 22 days	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	0.6277729835209225	[126,98]	[273,80,248]	7	hSpCas9	negative selection	5002025
32210570	32210592	18	+	27760321	HT29	viability after 22 days	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.32305542639735463	[156,122]	[188,205,212]	3	hSpCas9	negative selection	5002026
32204229	32204251	18	-	27760321	HT29	viability after 19 days	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	0.5017478364318755	[989,772]	[1812,1217,1295]	5	hSpCas9	negative selection	5085485
32204299	32204321	18	+	27760321	HT29	viability after 19 days	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	0.20911244968845555	[484,378]	[778,467,490]	2	hSpCas9	negative selection	5085486
32207401	32207423	18	+	27760321	HT29	viability after 19 days	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.18273998252379153	[370,289]	[541,173,576]	1	hSpCas9	negative selection	5085487
32208125	32208147	18	-	27760321	HT29	viability after 19 days	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	0.21444790745662523	[126,98]	[172,125,152]	2	hSpCas9	negative selection	5085488
32210570	32210592	18	+	27760321	HT29	viability after 19 days	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.4283745012833212	[156,122]	[280,229,144]	4	hSpCas9	negative selection	5085489
32204229	32204251	18	-	27760321	HT29	viability after 16 days	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	0.24079809451605727	[989,772]	[1514,630,1396]	2	hSpCas9	negative selection	5168948
32204299	32204321	18	+	27760321	HT29	viability after 16 days	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	-0.07858275214003127	[484,378]	[377,365,623]	-1	hSpCas9	negative selection	5168949
32207401	32207423	18	+	27760321	HT29	viability after 16 days	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.41317985164795823	[370,289]	[455,368,651]	4	hSpCas9	negative selection	5168950
32208125	32208147	18	-	27760321	HT29	viability after 16 days	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	0.33960229089047256	[126,98]	[212,78,194]	4	hSpCas9	negative selection	5168951
32210570	32210592	18	+	27760321	HT29	viability after 16 days	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.4578826654873597	[156,122]	[200,145,298]	5	hSpCas9	negative selection	5168952
32204229	32204251	18	-	27760321	HT29	viability after 13 days	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	0.10016127321297308	[989,772]	[1024,885,1360]	1	hSpCas9	negative selection	5252411
32204299	32204321	18	+	27760321	HT29	viability after 13 days	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	-0.07858827696942713	[484,378]	[521,329,565]	-1	hSpCas9	negative selection	5252412
32207401	32207423	18	+	27760321	HT29	viability after 13 days	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.2923861771761287	[370,289]	[452,302,641]	3	hSpCas9	negative selection	5252413
32208125	32208147	18	-	27760321	HT29	viability after 13 days	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	0.5701806949981356	[126,98]	[266,127,188]	7	hSpCas9	negative selection	5252414
32210570	32210592	18	+	27760321	HT29	viability after 13 days	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.22961722047489275	[156,122]	[216,140,211]	3	hSpCas9	negative selection	5252415
32204229	32204251	18	-	27760321	HT29	viability after 10 days	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	0.00825132501988568	[989,772]	[1142,1177,1003]	0	hSpCas9	negative selection	5335874
32204299	32204321	18	+	27760321	HT29	viability after 10 days	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	-0.629422903600243	[484,378]	[350,386,309]	-6	hSpCas9	negative selection	5335875
32207401	32207423	18	+	27760321	HT29	viability after 10 days	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.4792481042194622	[370,289]	[615,821,300]	6	hSpCas9	negative selection	5335876
32208125	32208147	18	-	27760321	HT29	viability after 10 days	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	0.47419183797006625	[126,98]	[168,109,303]	6	hSpCas9	negative selection	5335877
32210570	32210592	18	+	27760321	HT29	viability after 10 days	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.7444641481226962	[156,122]	[274,346,258]	8	hSpCas9	negative selection	5335878
32204229	32204251	18	-	27760321	MOLM13	viability	CGGTCACAGTTTGCCCCGATGG	MEP1B	ENSG00000141434	0.8106487780955851	[1172,989]	[1229,926]	5	hSpCas9	negative selection	5419337
32204299	32204321	18	+	27760321	MOLM13	viability	TGAGCAGTCGCGTTCTGACCGG	MEP1B	ENSG00000141434	-0.42740249921096873	[609,484]	[304,162]	-3	hSpCas9	negative selection	5419338
32207401	32207423	18	+	27760321	MOLM13	viability	GATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	-0.07524962729124389	[454,370]	[252,191]	0	hSpCas9	negative selection	5419339
32208125	32208147	18	-	27760321	MOLM13	viability	CACGAGTCCATAAAACTCAAGG	MEP1B	ENSG00000141434	0.8483060177420414	[170,126]	[243,69]	6	hSpCas9	negative selection	5419340
32210570	32210592	18	+	27760321	MOLM13	viability	GAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	-0.23712805930133762	[216,156]	[59,112]	-1	hSpCas9	negative selection	5419341
32190256	32190279	18	+	27661255	K562	viability	GTGTTTCTTCTTGGAGATTAGGG	MEP1B	ENSG00000141434	0.03581444250760113	[1378,1623]	[1449,1034]	1	dCas9-KRAB	negative selection	5492978
32192795	32192818	18	+	27260156	BXPC3	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.11439396199919638	[289]	[258,197,304,375]	-3	hSpCas9	negative selection	5555017
32192636	32192659	18	+	27260156	BXPC3	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.10862611848611747	[248]	[231,298,302,292]	2	hSpCas9	negative selection	5555018
32192763	32192786	18	+	27260156	BXPC3	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.27321067897380114	[572]	[645,509,847,936]	6	hSpCas9	negative selection	5555019
32191819	32191842	18	+	27260156	BXPC3	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.36678147337298783	[656]	[506,394,535,723]	-7	hSpCas9	negative selection	5619275
32192669	32192692	18	+	27260156	BXPC3	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.4528221192639805	[789]	[448,610,658,722]	-7	hSpCas9	negative selection	5619276
32195463	32195486	18	+	27260156	BXPC3	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.21253984384959734	[331]	[239,323,271,373]	-5	hSpCas9	negative selection	5619277
32192795	32192818	18	+	27260156	A673	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.0960042946141133	[289]	[446,363,274,413]	2	hSpCas9	negative selection	5676268
32192636	32192659	18	+	27260156	A673	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.0661874640633513	[248]	[281,255,285,319]	-2	hSpCas9	negative selection	5676269
32192763	32192786	18	+	27260156	A673	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.13612904734658055	[572]	[850,760,673,747]	3	hSpCas9	negative selection	5676270
32191819	32191842	18	+	27260156	A673	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.8241416226296849	[656]	[508,435,389,454]	-9	hSpCas9	negative selection	5740526
32192669	32192692	18	+	27260156	A673	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.36624340114287973	[789]	[724,716,735,764]	-7	hSpCas9	negative selection	5740527
32195463	32195486	18	+	27260156	A673	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.0009260404200227557	[331]	[557,255,357,447]	0	hSpCas9	negative selection	5740528
32192795	32192818	18	+	27260156	A375	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.4462064947840681	[289]	[534,436,432,438]	6	hSpCas9	negative selection	5797519
32192636	32192659	18	+	27260156	A375	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.10515253458148488	[248]	[278,330,254,228]	-1	hSpCas9	negative selection	5797520
32192763	32192786	18	+	27260156	A375	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.5762696324307643	[572]	[1073,1152,1018,788]	8	hSpCas9	negative selection	5797521
32191819	32191842	18	+	27260156	A375	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.24138845236477985	[656]	[616,908,667,458]	-3	hSpCas9	negative selection	5861777
32192669	32192692	18	+	27260156	A375	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.23758066586170257	[789]	[774,735,883,731]	-3	hSpCas9	negative selection	5861778
32195463	32195486	18	+	27260156	A375	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.3486575212623708	[331]	[609,433,605,334]	5	hSpCas9	negative selection	5861779
32192795	32192818	18	+	27260156	COLO741	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.057096129864348644	[289]	[425,298,348]	-1	hSpCas9	negative selection	5918770
32192636	32192659	18	+	27260156	COLO741	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.21524606229062393	[248]	[288,220,309]	-4	hSpCas9	negative selection	5918771
32192763	32192786	18	+	27260156	COLO741	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.041200140901716475	[572]	[1031,699,563]	0	hSpCas9	negative selection	5918772
32191819	32191842	18	+	27260156	COLO741	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.7317224241395792	[656]	[673,428,431]	-9	hSpCas9	negative selection	5983028
32192669	32192692	18	+	27260156	COLO741	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.2795756312569753	[789]	[752,910,822]	-5	hSpCas9	negative selection	5983029
32195463	32195486	18	+	27260156	COLO741	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.19642447624268022	[331]	[323,286,485]	-4	hSpCas9	negative selection	5983030
32192795	32192818	18	+	27260156	CAL120	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.12117712447591333	[289]	[307,257,423]	-2	hSpCas9	negative selection	6040021
32192636	32192659	18	+	27260156	CAL120	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.289650276354229	[248]	[468,264,414]	4	hSpCas9	negative selection	6040022
32192763	32192786	18	+	27260156	CAL120	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.579387497833156	[572]	[1089,678,1423]	8	hSpCas9	negative selection	6040023
32191819	32191842	18	+	27260156	CAL120	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.5263028681554354	[656]	[548,530,618]	-6	hSpCas9	negative selection	6104279
32192669	32192692	18	+	27260156	CAL120	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.2724847594598028	[789]	[1013,1012,450]	-4	hSpCas9	negative selection	6104280
32195463	32195486	18	+	27260156	CAL120	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.10774462189314382	[331]	[485,271,580]	1	hSpCas9	negative selection	6104281
32192795	32192818	18	+	27260156	CADOES1	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.2259366028813885	[289]	[239,214,170,298]	-4	hSpCas9	negative selection	6161272
32192636	32192659	18	+	27260156	CADOES1	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.20657628253440474	[248]	[212,197,132,260]	-4	hSpCas9	negative selection	6161273
32192763	32192786	18	+	27260156	CADOES1	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.2058907894494274	[572]	[735,493,463,769]	3	hSpCas9	negative selection	6161274
32191819	32191842	18	+	27260156	CADOES1	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.6417019582947158	[656]	[315,382,393,476]	-8	hSpCas9	negative selection	6225530
32192669	32192692	18	+	27260156	CADOES1	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.07236377582286191	[789]	[760,551,622,864]	-1	hSpCas9	negative selection	6225531
32195463	32195486	18	+	27260156	CADOES1	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.46181182038011603	[331]	[495,371,427,403]	7	hSpCas9	negative selection	6225532
32192795	32192818	18	+	27260156	EWS502	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.46146498155033466	[289]	[396,400,471,424]	7	hSpCas9	negative selection	6282523
32192636	32192659	18	+	27260156	EWS502	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.26931878897236083	[248]	[203,135,274,268]	-5	hSpCas9	negative selection	6282524
32192763	32192786	18	+	27260156	EWS502	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.420861776591441	[572]	[695,710,700,1181]	7	hSpCas9	negative selection	6282525
32191819	32191842	18	+	27260156	EWS502	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.686072689323106	[656]	[388,322,457,578]	-8	hSpCas9	negative selection	6346781
32192669	32192692	18	+	27260156	EWS502	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.39573802633207317	[789]	[531,564,613,861]	-6	hSpCas9	negative selection	6346782
32195463	32195486	18	+	27260156	EWS502	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.09906360467041847	[331]	[316,493,266,431]	1	hSpCas9	negative selection	6346783
32192795	32192818	18	+	27260156	EW8	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.3329586270016811	[289]	[193,221,161,172]	-6	hSpCas9	negative selection	6403774
32192636	32192659	18	+	27260156	EW8	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.14633141626923762	[248]	[250,218,185,245]	2	hSpCas9	negative selection	6403775
32192763	32192786	18	+	27260156	EW8	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.334710508528849	[572]	[645,622,536,549]	6	hSpCas9	negative selection	6403776
32191819	32191842	18	+	27260156	EW8	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.7023452189085465	[656]	[340,408,237,336]	-8	hSpCas9	negative selection	6468032
32192669	32192692	18	+	27260156	EW8	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.22551412269925486	[789]	[574,493,597,515]	-4	hSpCas9	negative selection	6468033
32195463	32195486	18	+	27260156	EW8	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.12758080882706746	[331]	[361,329,160,351]	2	hSpCas9	negative selection	6468034
32192795	32192818	18	+	27260156	CORL105	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.14147287651528628	[289]	[365,343,474,328]	2	hSpCas9	negative selection	6525025
32192636	32192659	18	+	27260156	CORL105	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.06285475975560417	[248]	[258,356,283,214]	-1	hSpCas9	negative selection	6525026
32192763	32192786	18	+	27260156	CORL105	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.30765040909401686	[572]	[817,721,1105,719]	6	hSpCas9	negative selection	6525027
32191819	32191842	18	+	27260156	CORL105	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.38757875330043734	[656]	[604,502,540,696]	-6	hSpCas9	negative selection	6589283
32192669	32192692	18	+	27260156	CORL105	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.3682322403949265	[789]	[870,561,690,745]	-6	hSpCas9	negative selection	6589284
32195463	32195486	18	+	27260156	CORL105	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.23087635519191674	[331]	[202,330,457,347]	-4	hSpCas9	negative selection	6589285
32192795	32192818	18	+	27260156	HS294T	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.20919181288517386	[289]	[105,88,135,202]	3	hSpCas9	negative selection	6646276
32192636	32192659	18	+	27260156	HS294T	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.9953490827780178	[248]	[71,98,513,77]	9	hSpCas9	negative selection	6646277
32192763	32192786	18	+	27260156	HS294T	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.6096846557989308	[572]	[318,361,373,288]	7	hSpCas9	negative selection	6646278
32191819	32191842	18	+	27260156	HS294T	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.715211812318703	[656]	[95,193,186,143]	-8	hSpCas9	negative selection	6710534
32192669	32192692	18	+	27260156	HS294T	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.12616510381489698	[789]	[282,316,241,273]	-2	hSpCas9	negative selection	6710535
32195463	32195486	18	+	27260156	HS294T	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.26568130436259263	[331]	[171,76,182,191]	3	hSpCas9	negative selection	6710536
32192795	32192818	18	+	27260156	HCC44	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.4278464975332345	[289]	[335,340,710,424]	7	hSpCas9	negative selection	6767527
32192636	32192659	18	+	27260156	HCC44	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.016716572375543248	[248]	[273,139,416,321]	0	hSpCas9	negative selection	6767528
32192763	32192786	18	+	27260156	HCC44	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.24551491098503353	[572]	[750,754,831,740]	4	hSpCas9	negative selection	6767529
32191819	32191842	18	+	27260156	HCC44	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.500267170246806	[656]	[282,569,569,648]	-6	hSpCas9	negative selection	6831785
32192669	32192692	18	+	27260156	HCC44	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	0.01575537244647296	[789]	[1460,527,837,872]	0	hSpCas9	negative selection	6831786
32195463	32195486	18	+	27260156	HCC44	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.07122814870751631	[331]	[552,254,420,384]	1	hSpCas9	negative selection	6831787
32192795	32192818	18	+	27260156	G402	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.268679127678422	[289]	[294,696,190,512]	3	hSpCas9	negative selection	6888778
32192636	32192659	18	+	27260156	G402	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.08608112940615231	[248]	[384,216,267,416]	1	hSpCas9	negative selection	6888779
32192763	32192786	18	+	27260156	G402	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.5314783073227299	[572]	[944,1310,812,978]	6	hSpCas9	negative selection	6888780
32191819	32191842	18	+	27260156	G402	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.347184108097231	[656]	[1140,379,455,601]	-4	hSpCas9	negative selection	6953036
32192669	32192692	18	+	27260156	G402	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.053663386061205576	[789]	[728,1417,655,908]	0	hSpCas9	negative selection	6953037
32195463	32195486	18	+	27260156	G402	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.25990528791220296	[331]	[667,474,330,489]	3	hSpCas9	negative selection	6953038
32192795	32192818	18	+	27260156	L33	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.28156712345566437	[289]	[378,155,256,241]	6	hSpCas9	negative selection	7010029
32192636	32192659	18	+	27260156	L33	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.2878411283852568	[248]	[240,78,301,303]	6	hSpCas9	negative selection	7010030
32192763	32192786	18	+	27260156	L33	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	-0.011609017930476029	[572]	[597,205,345,620]	0	hSpCas9	negative selection	7010031
32191819	32191842	18	+	27260156	L33	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.22666795526035727	[656]	[469,232,345,657]	-5	hSpCas9	negative selection	7074287
32192669	32192692	18	+	27260156	L33	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.32750071424781674	[789]	[593,231,437,661]	-6	hSpCas9	negative selection	7074288
32195463	32195486	18	+	27260156	L33	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.16060288142456347	[331]	[214,130,183,361]	-4	hSpCas9	negative selection	7074289
32192795	32192818	18	+	27260156	K562	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.3821704278055627	[289]	[234,633,136,340]	5	hSpCas9	negative selection	7131280
32192636	32192659	18	+	27260156	K562	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.8371571823880585	[248]	[145,68,133,141]	-7	hSpCas9	negative selection	7131281
32192763	32192786	18	+	27260156	K562	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.17058292921732898	[572]	[901,533,493,401]	2	hSpCas9	negative selection	7131282
32191819	32191842	18	+	27260156	K562	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.5740866494908814	[656]	[650,332,310,298]	-6	hSpCas9	negative selection	7195538
32192669	32192692	18	+	27260156	K562	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.43794203545116484	[789]	[1101,424,312,296]	-5	hSpCas9	negative selection	7195539
32195463	32195486	18	+	27260156	K562	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.0070904137568778	[331]	[398,444,247,116]	0	hSpCas9	negative selection	7195540
32192795	32192818	18	+	27260156	HT29	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.3481860021362889	[289]	[470,584,370,385]	6	hSpCas9	negative selection	7252531
32192636	32192659	18	+	27260156	HT29	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.05816499227396188	[248]	[310,313,354,281]	1	hSpCas9	negative selection	7252532
32192763	32192786	18	+	27260156	HT29	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.13496236510101534	[572]	[756,940,772,615]	2	hSpCas9	negative selection	7252533
32191819	32191842	18	+	27260156	HT29	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.4199397296742586	[656]	[604,406,643,698]	-6	hSpCas9	negative selection	7316789
32192669	32192692	18	+	27260156	HT29	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.290912725741736	[789]	[760,778,799,790]	-5	hSpCas9	negative selection	7316790
32195463	32195486	18	+	27260156	HT29	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.06078373108496116	[331]	[424,523,343,279]	-1	hSpCas9	negative selection	7316791
32192795	32192818	18	+	27260156	MHHES1	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.12609869778849903	[289]	[291,279,404,411]	2	hSpCas9	negative selection	7373782
32192636	32192659	18	+	27260156	MHHES1	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.1829565038089478	[248]	[462,384,213,244]	3	hSpCas9	negative selection	7373783
32192763	32192786	18	+	27260156	MHHES1	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.3483347634292082	[572]	[646,911,851,839]	6	hSpCas9	negative selection	7373784
32191819	32191842	18	+	27260156	MHHES1	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.44665608784701216	[656]	[610,500,599,468]	-7	hSpCas9	negative selection	7438040
32192669	32192692	18	+	27260156	MHHES1	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.21399048818107658	[789]	[965,995,734,470]	-4	hSpCas9	negative selection	7438041
32195463	32195486	18	+	27260156	MHHES1	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.12245474253247884	[331]	[645,284,359,355]	2	hSpCas9	negative selection	7438042
32192795	32192818	18	+	27260156	MEWO	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.28370475110689564	[289]	[301,204,176]	-6	hSpCas9	negative selection	7495033
32192636	32192659	18	+	27260156	MEWO	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.01833432423127035	[248]	[275,135,303]	0	hSpCas9	negative selection	7495034
32192763	32192786	18	+	27260156	MEWO	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.19335105602891078	[572]	[783,382,705]	4	hSpCas9	negative selection	7495035
32191819	32191842	18	+	27260156	MEWO	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.5189881568335358	[656]	[501,409,388]	-8	hSpCas9	negative selection	7559291
32192669	32192692	18	+	27260156	MEWO	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.3561474783860744	[789]	[647,534,562]	-6	hSpCas9	negative selection	7559292
32195463	32195486	18	+	27260156	MEWO	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.12454545311129411	[331]	[331,436,244]	2	hSpCas9	negative selection	7559293
32192795	32192818	18	+	27260156	LNCAPCLONEFGC	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.535844705795351	[289]	[468,337,324,383]	8	hSpCas9	negative selection	7616284
32192636	32192659	18	+	27260156	LNCAPCLONEFGC	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.09090217066995743	[248]	[194,267,200,177]	-1	hSpCas9	negative selection	7616285
32192763	32192786	18	+	27260156	LNCAPCLONEFGC	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.45654786812307846	[572]	[873,521,812,663]	7	hSpCas9	negative selection	7616286
32191819	32191842	18	+	27260156	LNCAPCLONEFGC	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.5542820578867054	[656]	[332,411,412,464]	-7	hSpCas9	negative selection	7680542
32192669	32192692	18	+	27260156	LNCAPCLONEFGC	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.09379676467952036	[789]	[625,642,740,684]	-1	hSpCas9	negative selection	7680543
32195463	32195486	18	+	27260156	LNCAPCLONEFGC	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.08274754076505025	[331]	[336,308,297,326]	1	hSpCas9	negative selection	7680544
32192795	32192818	18	+	27260156	PANC0327	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.2909616293629904	[289]	[220,286,115,208]	-4	hSpCas9	negative selection	7737535
32192636	32192659	18	+	27260156	PANC0327	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.42350770781612945	[248]	[108,157,206,181]	-6	hSpCas9	negative selection	7737536
32192763	32192786	18	+	27260156	PANC0327	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.28517036161721765	[572]	[436,628,818,579]	4	hSpCas9	negative selection	7737537
32191819	32191842	18	+	27260156	PANC0327	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.9355573472001911	[656]	[329,255,378,263]	-8	hSpCas9	negative selection	7801793
32192669	32192692	18	+	27260156	PANC0327	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.19741499765616422	[789]	[708,337,1009,434]	-3	hSpCas9	negative selection	7801794
32195463	32195486	18	+	27260156	PANC0327	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.020167339815208685	[331]	[287,181,314,391]	0	hSpCas9	negative selection	7801795
32192795	32192818	18	+	27260156	NCIH2009	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.21713263592322807	[289]	[405,487,504]	3	hSpCas9	negative selection	7858786
32192636	32192659	18	+	27260156	NCIH2009	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.06824610280279064	[248]	[482,308,325]	0	hSpCas9	negative selection	7858787
32192763	32192786	18	+	27260156	NCIH2009	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.6202116298497872	[572]	[1176,954,1551]	8	hSpCas9	negative selection	7858788
32191819	32191842	18	+	27260156	NCIH2009	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.3540183490974613	[656]	[1086,621,518]	-5	hSpCas9	negative selection	7923044
32192669	32192692	18	+	27260156	NCIH2009	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.4287268368689765	[789]	[742,840,858]	-5	hSpCas9	negative selection	7923045
32195463	32195486	18	+	27260156	NCIH2009	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.43021386848182397	[331]	[342,339,348]	-5	hSpCas9	negative selection	7923046
32192795	32192818	18	+	27260156	NCIH1373	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.3952974283876824	[289]	[624,186,513,114]	4	hSpCas9	negative selection	7980037
32192636	32192659	18	+	27260156	NCIH1373	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.46573283727496706	[248]	[267,313,544,104]	4	hSpCas9	negative selection	7980038
32192763	32192786	18	+	27260156	NCIH1373	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.6779654158854233	[572]	[1646,717,583,344]	6	hSpCas9	negative selection	7980039
32191819	32191842	18	+	27260156	NCIH1373	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.19430043302607725	[656]	[722,430,868,150]	-2	hSpCas9	negative selection	8044295
32192669	32192692	18	+	27260156	NCIH1373	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.14468953591325173	[789]	[1058,495,730,262]	-1	hSpCas9	negative selection	8044296
32195463	32195486	18	+	27260156	NCIH1373	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.05996215605877259	[331]	[632,434,166,91]	0	hSpCas9	negative selection	8044297
32192795	32192818	18	+	27260156	PATU8902	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.49693010992607894	[289]	[609,322,449,969]	5	hSpCas9	negative selection	8101288
32192636	32192659	18	+	27260156	PATU8902	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.6858686561996429	[248]	[127,142,303,269]	-6	hSpCas9	negative selection	8101289
32192763	32192786	18	+	27260156	PATU8902	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.335712982025027	[572]	[837,1187,1089,868]	3	hSpCas9	negative selection	8101290
32191819	32191842	18	+	27260156	PATU8902	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.9182924442974973	[656]	[730,390,449,349]	-7	hSpCas9	negative selection	8165546
32192669	32192692	18	+	27260156	PATU8902	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.4141537523072044	[789]	[563,827,960,922]	-4	hSpCas9	negative selection	8165547
32195463	32195486	18	+	27260156	PATU8902	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.09337109865992815	[331]	[663,733,221,407]	0	hSpCas9	negative selection	8165548
32192795	32192818	18	+	27260156	PANC1	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.2852452112235769	[289]	[277,455,320,202]	4	hSpCas9	negative selection	8222539
32192636	32192659	18	+	27260156	PANC1	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.4576607969571626	[248]	[355,531,143,199]	7	hSpCas9	negative selection	8222540
32192763	32192786	18	+	27260156	PANC1	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.4925074457818399	[572]	[622,854,956,407]	7	hSpCas9	negative selection	8222541
32191819	32191842	18	+	27260156	PANC1	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.7569894721380208	[656]	[337,431,262,318]	-8	hSpCas9	negative selection	8286797
32192669	32192692	18	+	27260156	PANC1	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.06104082772970787	[789]	[612,928,717,426]	-1	hSpCas9	negative selection	8286798
32195463	32195486	18	+	27260156	PANC1	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.2814049885300163	[331]	[261,415,91,204]	-4	hSpCas9	negative selection	8286799
32192795	32192818	18	+	27260156	PANC0813	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.24961365946581326	[289]	[312,284,246,301]	-4	hSpCas9	negative selection	8343790
32192636	32192659	18	+	27260156	PANC0813	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.2734622879231955	[248]	[265,228,271,204]	-4	hSpCas9	negative selection	8343791
32192763	32192786	18	+	27260156	PANC0813	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.5552186689289516	[572]	[604,1128,1131,1049]	8	hSpCas9	negative selection	8343792
32191819	32191842	18	+	27260156	PANC0813	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.4499361210417176	[656]	[582,610,427,633]	-6	hSpCas9	negative selection	8408048
32192669	32192692	18	+	27260156	PANC0813	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.8712892746792917	[789]	[770,626,319,342]	-8	hSpCas9	negative selection	8408049
32195463	32195486	18	+	27260156	PANC0813	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.6797691536471989	[331]	[303,302,223,152]	-7	hSpCas9	negative selection	8408050
32192795	32192818	18	+	27260156	RDES	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.1421388492270249	[289]	[277,279,340,309]	-2	hSpCas9	negative selection	8465041
32192636	32192659	18	+	27260156	RDES	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.11840585702685369	[248]	[215,309,280,242]	-2	hSpCas9	negative selection	8465042
32192763	32192786	18	+	27260156	RDES	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.3835578591905717	[572]	[628,776,946,1169]	6	hSpCas9	negative selection	8465043
32191819	32191842	18	+	27260156	RDES	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.706239230054064	[656]	[441,435,427,549]	-8	hSpCas9	negative selection	8529299
32192669	32192692	18	+	27260156	RDES	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.14068531291060749	[789]	[717,674,916,1033]	-2	hSpCas9	negative selection	8529300
32195463	32195486	18	+	27260156	RDES	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.0854026163708288	[331]	[408,314,391,294]	-1	hSpCas9	negative selection	8529301
32192795	32192818	18	+	27260156	PC3	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.08952409579721388	[289]	[253,169,230,396]	-2	hSpCas9	negative selection	8586292
32192636	32192659	18	+	27260156	PC3	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.5766673858637404	[248]	[105,142,357,143]	-8	hSpCas9	negative selection	8586293
32192763	32192786	18	+	27260156	PC3	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.21637971377623022	[572]	[474,643,1014,667]	5	hSpCas9	negative selection	8586294
32191819	32191842	18	+	27260156	PC3	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.5672762817917547	[656]	[367,168,806,565]	-8	hSpCas9	negative selection	8650550
32192669	32192692	18	+	27260156	PC3	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.28193964485727846	[789]	[510,541,935,704]	-6	hSpCas9	negative selection	8650551
32195463	32195486	18	+	27260156	PC3	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.25118308709884696	[331]	[119,260,475,387]	-5	hSpCas9	negative selection	8650552
32192795	32192818	18	+	27260156	PATU8988T	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.019586309331621976	[289]	[358,275,210,290]	0	hSpCas9	negative selection	8707543
32192636	32192659	18	+	27260156	PATU8988T	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.2049404225116347	[248]	[199,255,469,169]	3	hSpCas9	negative selection	8707544
32192763	32192786	18	+	27260156	PATU8988T	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	-0.11858695348659179	[572]	[489,616,462,477]	-2	hSpCas9	negative selection	8707545
32191819	32191842	18	+	27260156	PATU8988T	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.9475325198837775	[656]	[255,436,305,327]	-8	hSpCas9	negative selection	8771801
32192669	32192692	18	+	27260156	PATU8988T	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.17014969718580963	[789]	[303,694,761,976]	-3	hSpCas9	negative selection	8771802
32195463	32195486	18	+	27260156	PATU8988T	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.3013047699257403	[331]	[323,268,190,258]	-5	hSpCas9	negative selection	8771803
32192795	32192818	18	+	27260156	T47D	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.015303770945102602	[289]	[338,321,341,334]	0	hSpCas9	negative selection	8828794
32192636	32192659	18	+	27260156	T47D	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.044313021532456975	[248]	[283,241,278,324]	-1	hSpCas9	negative selection	8828795
32192763	32192786	18	+	27260156	T47D	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.2586660677000766	[572]	[787,722,875,812]	5	hSpCas9	negative selection	8828796
32191819	32191842	18	+	27260156	T47D	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.5645905390787274	[656]	[513,446,449,670]	-8	hSpCas9	negative selection	8893052
32192669	32192692	18	+	27260156	T47D	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.24145574536131575	[789]	[830,849,746,676]	-5	hSpCas9	negative selection	8893053
32195463	32195486	18	+	27260156	T47D	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.012109374707815257	[331]	[315,385,396,435]	0	hSpCas9	negative selection	8893054
32192795	32192818	18	+	27260156	SU8686	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.2816312430022127	[289]	[377,364,255,395]	5	hSpCas9	negative selection	8950045
32192636	32192659	18	+	27260156	SU8686	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.19252630108660695	[248]	[187,226,277,483]	3	hSpCas9	negative selection	8950046
32192763	32192786	18	+	27260156	SU8686	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.3095422065646345	[572]	[783,473,690,916]	5	hSpCas9	negative selection	8950047
32191819	32191842	18	+	27260156	SU8686	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.5504028337628404	[656]	[406,523,418,413]	-7	hSpCas9	negative selection	9014303
32192669	32192692	18	+	27260156	SU8686	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.23982443811389675	[789]	[559,619,603,921]	-4	hSpCas9	negative selection	9014304
32195463	32195486	18	+	27260156	SU8686	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.1092451248419416	[331]	[337,292,231,359]	-2	hSpCas9	negative selection	9014305
32192795	32192818	18	+	27260156	SKES1	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.3539078591625942	[289]	[389,369,347,369]	7	hSpCas9	negative selection	9071296
32192636	32192659	18	+	27260156	SKES1	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.32887832700026187	[248]	[164,198,230,189]	-6	hSpCas9	negative selection	9071297
32192763	32192786	18	+	27260156	SKES1	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.3585232163630723	[572]	[621,905,732,674]	7	hSpCas9	negative selection	9071298
32191819	32191842	18	+	27260156	SKES1	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.5215427179755031	[656]	[349,585,455,432]	-8	hSpCas9	negative selection	9135554
32192669	32192692	18	+	27260156	SKES1	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.41512910799228014	[789]	[673,584,545,566]	-7	hSpCas9	negative selection	9135555
32195463	32195486	18	+	27260156	SKES1	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.0708781288226914	[331]	[276,348,277,348]	-1	hSpCas9	negative selection	9135556
32192795	32192818	18	+	27260156	TOV112D	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.4032162687204308	[289]	[482,579,350,183]	7	hSpCas9	negative selection	9192547
32192636	32192659	18	+	27260156	TOV112D	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	0.06058912728986321	[248]	[189,249,348,242]	1	hSpCas9	negative selection	9192548
32192763	32192786	18	+	27260156	TOV112D	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.37679191791761857	[572]	[625,1128,568,739]	7	hSpCas9	negative selection	9192549
32191819	32191842	18	+	27260156	TOV112D	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.928503651226332	[656]	[247,375,391,364]	-9	hSpCas9	negative selection	9256805
32192669	32192692	18	+	27260156	TOV112D	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.11504645664021318	[789]	[713,886,727,631]	-2	hSpCas9	negative selection	9256806
32195463	32195486	18	+	27260156	TOV112D	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.34288276868949175	[331]	[449,578,374,325]	6	hSpCas9	negative selection	9256807
32192795	32192818	18	+	27260156	TC71	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	0.20570637580302564	[289]	[329,331,380,392]	5	hSpCas9	negative selection	9313798
32192636	32192659	18	+	27260156	TC71	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.0328950751426762	[248]	[301,268,164,312]	-1	hSpCas9	negative selection	9313799
32192763	32192786	18	+	27260156	TC71	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.1629057606330837	[572]	[645,638,681,790]	4	hSpCas9	negative selection	9313800
32191819	32191842	18	+	27260156	TC71	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.5994301504350218	[656]	[439,540,399,481]	-9	hSpCas9	negative selection	9378056
32192669	32192692	18	+	27260156	TC71	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.10763026027011191	[789]	[754,846,790,748]	-3	hSpCas9	negative selection	9378057
32195463	32195486	18	+	27260156	TC71	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	0.26264633622974937	[331]	[303,301,475,639]	6	hSpCas9	negative selection	9378058
32192795	32192818	18	+	27260156	TC32	viability	AGGGTGACATCAGACTTGATAGG	MEP1B	ENSG00000141434	-0.8197844167895052	[289]	[179,40,213,228]	-9	hSpCas9	negative selection	9435049
32192636	32192659	18	+	27260156	TC32	viability	TTAATCAAAGATGTAGATGGCGG	MEP1B	ENSG00000141434	-0.5094515974152395	[248]	[179,65,279,178]	-7	hSpCas9	negative selection	9435050
32192763	32192786	18	+	27260156	TC32	viability	TTTACTCTTAGGTTTGGGACTGG	MEP1B	ENSG00000141434	0.23894332956348474	[572]	[576,531,800,669]	4	hSpCas9	negative selection	9435051
32191819	32191842	18	+	27260156	TC32	viability	CAGGCAACTCCAGAAAACTTTGG	MEP1B	ENSG00000141434	-0.7123784632866454	[656]	[336,216,754,304]	-8	hSpCas9	negative selection	9499307
32192669	32192692	18	+	27260156	TC32	viability	GACATATTTGATATCAATGAAGG	MEP1B	ENSG00000141434	-0.28805335283165623	[789]	[570,489,862,561]	-5	hSpCas9	negative selection	9499308
32195463	32195486	18	+	27260156	TC32	viability	ATATGTTCTAGAAGATAGCTTGG	MEP1B	ENSG00000141434	-0.1279564325711261	[331]	[188,224,473,306]	-2	hSpCas9	negative selection	9499309
32192647	32192670	18	+	27869803	HPAFII	viability after 27 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	-0.4008751742599738	[291]	[76,148,NaN]	-3	hSpCas9	negative selection	9564398
32204299	32204322	18	+	27869803	HPAFII	viability after 27 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.24998756635636937	[313]	[200,86,NaN]	-2	hSpCas9	negative selection	9564399
32207400	32207423	18	+	27869803	HPAFII	viability after 27 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.6210647384773617	[236]	[237,152,NaN]	5	hSpCas9	negative selection	9564400
32208237	32208260	18	+	27869803	HPAFII	viability after 27 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	0.6700322477561241	[376]	[430,218,NaN]	5	hSpCas9	negative selection	9564401
32213122	32213145	18	-	27869803	HPAFII	viability after 27 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	0.1236330277659703	[172]	[55,134,NaN]	1	hSpCas9	negative selection	9564402
32217080	32217103	18	+	27869803	HPAFII	viability after 27 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.43737244741995185	[180]	[120,27,NaN]	-3	hSpCas9	negative selection	9564403
32192647	32192670	18	+	27869803	HPAFII	viability after 15 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	-0.07996040845381996	[291]	[307,289,NaN]	-1	hSpCas9	negative selection	9646847
32204299	32204322	18	+	27869803	HPAFII	viability after 15 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.32110931675890847	[313]	[361,212,NaN]	-4	hSpCas9	negative selection	9646848
32207400	32207423	18	+	27869803	HPAFII	viability after 15 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.58856290913532	[236]	[604,244,NaN]	6	hSpCas9	negative selection	9646849
32208237	32208260	18	+	27869803	HPAFII	viability after 15 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	0.5394215375257408	[376]	[845,428,NaN]	6	hSpCas9	negative selection	9646850
32213122	32213145	18	-	27869803	HPAFII	viability after 15 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	0.22286649512435786	[172]	[261,188,NaN]	2	hSpCas9	negative selection	9646851
32217080	32217103	18	+	27869803	HPAFII	viability after 15 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.06507733883478395	[180]	[221,191,NaN]	0	hSpCas9	negative selection	9646852
32192647	32192670	18	+	27869803	ASPC1	viability after 36 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.2941836283487486	[680]	[342,180,339]	3	hSpCas9	negative selection	9729296
32204299	32204322	18	+	27869803	ASPC1	viability after 36 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.3384513201323409	[834]	[259,157,264]	-3	hSpCas9	negative selection	9729297
32207400	32207423	18	+	27869803	ASPC1	viability after 36 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	-0.07773876378111576	[657]	[255,289,130]	-1	hSpCas9	negative selection	9729298
32208237	32208260	18	+	27869803	ASPC1	viability after 36 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.038824295648006046	[843]	[239,376,244]	0	hSpCas9	negative selection	9729299
32213122	32213145	18	-	27869803	ASPC1	viability after 36 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.19580667687600323	[623]	[321,248,48]	-2	hSpCas9	negative selection	9729300
32217080	32217103	18	+	27869803	ASPC1	viability after 36 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.2991427820443826	[453]	[203,106,91]	-3	hSpCas9	negative selection	9729301
32192647	32192670	18	+	27869803	PATU8988S	viability after 35 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	0.9257788584575053	[493]	[361,393,NaN]	8	hSpCas9	negative selection	9811745
32204299	32204322	18	+	27869803	PATU8988S	viability after 35 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	0.7095597488627802	[895]	[424,755,NaN]	7	hSpCas9	negative selection	9811746
32207400	32207423	18	+	27869803	PATU8988S	viability after 35 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	-0.00536127958811191	[527]	[151,271,NaN]	0	hSpCas9	negative selection	9811747
32208237	32208260	18	+	27869803	PATU8988S	viability after 35 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.20653079120147866	[814]	[266,301,NaN]	-2	hSpCas9	negative selection	9811748
32213122	32213145	18	-	27869803	PATU8988S	viability after 35 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.33661100335748784	[513]	[134,192,NaN]	-4	hSpCas9	negative selection	9811749
32217080	32217103	18	+	27869803	PATU8988S	viability after 35 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.24246462154167675	[338]	[169,152,NaN]	3	hSpCas9	negative selection	9811750
32192647	32192670	18	+	27869803	PATU8988S	viability after 31 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	1.08058286633955	[493]	[365,480,NaN]	9	hSpCas9	negative selection	9894194
32204299	32204322	18	+	27869803	PATU8988S	viability after 31 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	0.13973525010291477	[895]	[247,578,NaN]	1	hSpCas9	negative selection	9894195
32207400	32207423	18	+	27869803	PATU8988S	viability after 31 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.05475233769582612	[527]	[219,216,NaN]	0	hSpCas9	negative selection	9894196
32208237	32208260	18	+	27869803	PATU8988S	viability after 31 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	-0.0940249406486886	[814]	[263,355,NaN]	-1	hSpCas9	negative selection	9894197
32213122	32213145	18	-	27869803	PATU8988S	viability after 31 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.31356892062360575	[513]	[145,188,NaN]	-4	hSpCas9	negative selection	9894198
32217080	32217103	18	+	27869803	PATU8988S	viability after 31 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.16310625742209617	[338]	[120,189,NaN]	2	hSpCas9	negative selection	9894199
32192647	32192670	18	+	27869803	HPAFII	viability after 35 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	-0.9399130462926538	[291]	[69,84,NaN]	-5	hSpCas9	negative selection	9976643
32204299	32204322	18	+	27869803	HPAFII	viability after 35 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.6430728875586833	[313]	[153,42,NaN]	-4	hSpCas9	negative selection	9976644
32207400	32207423	18	+	27869803	HPAFII	viability after 35 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.6022361338801969	[236]	[223,134,NaN]	4	hSpCas9	negative selection	9976645
32208237	32208260	18	+	27869803	HPAFII	viability after 35 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	0.794251876935885	[376]	[401,250,NaN]	5	hSpCas9	negative selection	9976646
32213122	32213145	18	-	27869803	HPAFII	viability after 35 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.25967186576906376	[172]	[27,123,NaN]	-2	hSpCas9	negative selection	9976647
32217080	32217103	18	+	27869803	HPAFII	viability after 35 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.3374157166988796	[180]	[56,89,NaN]	-2	hSpCas9	negative selection	9976648
32192647	32192670	18	+	27869803	HPAFII	viability after 31 days	TGTAGATGGCGGAATGGACCAGG	MEP1B	ENSG00000141434	-0.7259521971842087	[291]	[44,157,NaN]	-5	hSpCas9	negative selection	10059092
32204299	32204322	18	+	27869803	HPAFII	viability after 31 days	TGAGCAGTCGCGTTCTGACCGGG	MEP1B	ENSG00000141434	-0.4863433550077816	[313]	[176,69,NaN]	-3	hSpCas9	negative selection	10059093
32207400	32207423	18	+	27869803	HPAFII	viability after 31 days	GGATGTGATCGGCCAACGAATGG	MEP1B	ENSG00000141434	0.6594131513471643	[236]	[289,122,NaN]	5	hSpCas9	negative selection	10059094
32208237	32208260	18	+	27869803	HPAFII	viability after 31 days	AGAGAGTGATCACTCCAACATGG	MEP1B	ENSG00000141434	0.6378962187138483	[376]	[378,274,NaN]	4	hSpCas9	negative selection	10059095
32213122	32213145	18	-	27869803	HPAFII	viability after 31 days	ATAAAGTTGCCAGCTCCCAGTGG	MEP1B	ENSG00000141434	-0.258864830514389	[172]	[61,101,NaN]	-2	hSpCas9	negative selection	10059096
32217080	32217103	18	+	27869803	HPAFII	viability after 31 days	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.5517944619108115	[180]	[224,65,NaN]	4	hSpCas9	negative selection	10059097
32217080	32217103	18	+	28162770	P31FUJ	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.7473529841887501	[182]	[360]	8	hSpCas9	negative selection	10191064
32217763	32217786	18	+	28162770	P31FUJ	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	0.08626623633374322	[201]	[251]	0	hSpCas9	negative selection	10191065
32204275	32204298	18	-	28162770	P31FUJ	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.05608562870897603	[211]	[258]	0	hSpCas9	negative selection	10191066
32208191	32208214	18	+	28162770	P31FUJ	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	-0.30565276982206024	[263]	[250]	-3	hSpCas9	negative selection	10191067
32208211	32208234	18	+	28162770	P31FUJ	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	1.0293047214511881	[388]	[932]	9	hSpCas9	negative selection	10191068
32210569	32210592	18	+	28162770	P31FUJ	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.455253789270881	[107]	[173]	5	hSpCas9	negative selection	10191069
32213178	32213201	18	+	28162770	P31FUJ	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.806356171556734	[526]	[1082]	8	hSpCas9	negative selection	10191070
32215144	32215167	18	+	28162770	P31FUJ	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.6646743607862673	[327]	[610]	7	hSpCas9	negative selection	10191071
32217033	32217056	18	-	28162770	P31FUJ	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.4162483455103097	[267]	[235]	-4	hSpCas9	negative selection	10191072
32217096	32217119	18	+	28162770	P31FUJ	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	1.2575234221687026	[20]	[58]	9	hSpCas9	negative selection	10191073
32217080	32217103	18	+	28162770	TF1	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	NaN	[NaN]	[311]	1	hSpCas9	negative selection	10360430
32217763	32217786	18	+	28162770	TF1	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	NaN	[NaN]	[157]	1	hSpCas9	negative selection	10360431
32204275	32204298	18	-	28162770	TF1	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10360432
32208191	32208214	18	+	28162770	TF1	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	NaN	[NaN]	[345]	1	hSpCas9	negative selection	10360433
32208211	32208234	18	+	28162770	TF1	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	NaN	[NaN]	[356]	1	hSpCas9	negative selection	10360434
32210569	32210592	18	+	28162770	TF1	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10360435
32213178	32213201	18	+	28162770	TF1	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	NaN	[NaN]	[532]	1	hSpCas9	negative selection	10360436
32215144	32215167	18	+	28162770	TF1	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	NaN	[NaN]	[277]	1	hSpCas9	negative selection	10360437
32217033	32217056	18	-	28162770	TF1	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10360438
32217096	32217119	18	+	28162770	TF1	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10360439
32217080	32217103	18	+	28162770	SKM1	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.4150374992788438	[41]	[98]	4	hSpCas9	negative selection	10529796
32217763	32217786	18	+	28162770	SKM1	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	-0.5780761151359164	[37]	[44]	-4	hSpCas9	negative selection	10529797
32204275	32204298	18	-	28162770	SKM1	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.01544528919203468	[60]	[108]	0	hSpCas9	negative selection	10529798
32208191	32208214	18	+	28162770	SKM1	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	0.45810622117072974	[62]	[152]	4	hSpCas9	negative selection	10529799
32208211	32208234	18	+	28162770	SKM1	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.03839223468241282	[102]	[186]	0	hSpCas9	negative selection	10529800
32210569	32210592	18	+	28162770	SKM1	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.251247284008633	[47]	[100]	2	hSpCas9	negative selection	10529801
32213178	32213201	18	+	28162770	SKM1	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	-0.0729632715552242	[118]	[199]	0	hSpCas9	negative selection	10529802
32215144	32215167	18	+	28162770	SKM1	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.37641186038000274	[77]	[178]	3	hSpCas9	negative selection	10529803
32217033	32217056	18	-	28162770	SKM1	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.23703919730084932	[37]	[56]	-2	hSpCas9	negative selection	10529804
32217096	32217119	18	+	28162770	SKM1	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	-1.2370391973008492	[11]	[8]	-7	hSpCas9	negative selection	10529805
32217080	32217103	18	+	28162770	SKM1	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.4150374992788438	[41]	[98]	4	hSpCas9	negative selection	10699162
32217763	32217786	18	+	28162770	SKM1	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	-0.5780761151359164	[37]	[44]	-4	hSpCas9	negative selection	10699163
32204275	32204298	18	-	28162770	SKM1	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.01544528919203468	[60]	[108]	0	hSpCas9	negative selection	10699164
32208191	32208214	18	+	28162770	SKM1	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	0.45810622117072974	[62]	[152]	4	hSpCas9	negative selection	10699165
32208211	32208234	18	+	28162770	SKM1	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.03839223468241282	[102]	[186]	0	hSpCas9	negative selection	10699166
32210569	32210592	18	+	28162770	SKM1	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.251247284008633	[47]	[100]	2	hSpCas9	negative selection	10699167
32213178	32213201	18	+	28162770	SKM1	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	-0.0729632715552242	[118]	[199]	0	hSpCas9	negative selection	10699168
32215144	32215167	18	+	28162770	SKM1	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.37641186038000274	[77]	[178]	3	hSpCas9	negative selection	10699169
32217033	32217056	18	-	28162770	SKM1	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.23703919730084932	[37]	[56]	-2	hSpCas9	negative selection	10699170
32217096	32217119	18	+	28162770	SKM1	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	-1.2370391973008492	[11]	[8]	-7	hSpCas9	negative selection	10699171
32217080	32217103	18	+	28162770	PL21	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.9539790272199224	[152]	[128]	7	hSpCas9	negative selection	10868528
32217763	32217786	18	+	28162770	PL21	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	0.7707468222334064	[100]	[74]	6	hSpCas9	negative selection	10868529
32204275	32204298	18	-	28162770	PL21	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	-0.15741239012876374	[245]	[95]	-1	hSpCas9	negative selection	10868530
32208191	32208214	18	+	28162770	PL21	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	1.043863674558859	[262]	[235]	8	hSpCas9	negative selection	10868531
32208211	32208234	18	+	28162770	PL21	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	-0.15616405999905725	[360]	[140]	-1	hSpCas9	negative selection	10868532
32210569	32210592	18	+	28162770	PL21	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.9635333339331713	[118]	[100]	7	hSpCas9	negative selection	10868533
32213178	32213201	18	+	28162770	PL21	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.8564619362115029	[400]	[315]	7	hSpCas9	negative selection	10868534
32215144	32215167	18	+	28162770	PL21	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.5010706280816426	[262]	[161]	4	hSpCas9	negative selection	10868535
32217033	32217056	18	-	28162770	PL21	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-1.8957848055092157	[170]	[19]	-8	hSpCas9	negative selection	10868536
32217096	32217119	18	+	28162770	PL21	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	-0.8702497134020781	[20]	[4]	-5	hSpCas9	negative selection	10868537
32217080	32217103	18	+	28162770	P31FUJ	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.7473529841887501	[182]	[360]	8	hSpCas9	negative selection	11037894
32217763	32217786	18	+	28162770	P31FUJ	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	0.08626623633374322	[201]	[251]	0	hSpCas9	negative selection	11037895
32204275	32204298	18	-	28162770	P31FUJ	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.05608562870897603	[211]	[258]	0	hSpCas9	negative selection	11037896
32208191	32208214	18	+	28162770	P31FUJ	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	-0.30565276982206024	[263]	[250]	-3	hSpCas9	negative selection	11037897
32208211	32208234	18	+	28162770	P31FUJ	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	1.0293047214511881	[388]	[932]	9	hSpCas9	negative selection	11037898
32210569	32210592	18	+	28162770	P31FUJ	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.455253789270881	[107]	[173]	5	hSpCas9	negative selection	11037899
32213178	32213201	18	+	28162770	P31FUJ	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.806356171556734	[526]	[1082]	8	hSpCas9	negative selection	11037900
32215144	32215167	18	+	28162770	P31FUJ	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.6646743607862673	[327]	[610]	7	hSpCas9	negative selection	11037901
32217033	32217056	18	-	28162770	P31FUJ	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.4162483455103097	[267]	[235]	-4	hSpCas9	negative selection	11037902
32217096	32217119	18	+	28162770	P31FUJ	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	1.2575234221687026	[20]	[58]	9	hSpCas9	negative selection	11037903
32217080	32217103	18	+	28162770	OCIAML5	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.12136370873210048	[136]	[268]	1	hSpCas9	negative selection	11207260
32217763	32217786	18	+	28162770	OCIAML5	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	0.4122740324704218	[91]	[220]	3	hSpCas9	negative selection	11207261
32204275	32204298	18	-	28162770	OCIAML5	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.5281383566227253	[130]	[340]	4	hSpCas9	negative selection	11207262
32208191	32208214	18	+	28162770	OCIAML5	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	0.9892356831169448	[119]	[429]	8	hSpCas9	negative selection	11207263
32208211	32208234	18	+	28162770	OCIAML5	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.870399453607094	[129]	[428]	7	hSpCas9	negative selection	11207264
32210569	32210592	18	+	28162770	OCIAML5	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	-0.8188997069287975	[85]	[87]	-5	hSpCas9	negative selection	11207265
32213178	32213201	18	+	28162770	OCIAML5	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.8710583689146837	[198]	[656]	7	hSpCas9	negative selection	11207266
32215144	32215167	18	+	28162770	OCIAML5	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.9725405154153723	[189]	[672]	8	hSpCas9	negative selection	11207267
32217033	32217056	18	-	28162770	OCIAML5	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.28571974831018776	[103]	[153]	-2	hSpCas9	negative selection	11207268
32217096	32217119	18	+	28162770	OCIAML5	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	0.41096783496979716	[14]	[35]	3	hSpCas9	negative selection	11207269
32217080	32217103	18	+	28162770	EOL1	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	-0.20266124847256137	[390]	[178]	-1	hSpCas9	negative selection	11376626
32217763	32217786	18	+	28162770	EOL1	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	1.042603533092247	[128]	[139]	8	hSpCas9	negative selection	11376627
32204275	32204298	18	-	28162770	EOL1	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	-0.7955743124322575	[368]	[111]	-5	hSpCas9	negative selection	11376628
32208191	32208214	18	+	28162770	EOL1	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	1.6898865129008227	[432]	[735]	9	hSpCas9	negative selection	11376629
32208211	32208234	18	+	28162770	EOL1	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.8721631913905208	[644]	[621]	7	hSpCas9	negative selection	11376630
32210569	32210592	18	+	28162770	EOL1	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.26201671735367493	[276]	[174]	2	hSpCas9	negative selection	11376631
32213178	32213201	18	+	28162770	EOL1	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	-0.11465011614211407	[484]	[235]	-1	hSpCas9	negative selection	11376632
32215144	32215167	18	+	28162770	EOL1	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.0029744185273508084	[357]	[188]	0	hSpCas9	negative selection	11376633
32217033	32217056	18	-	28162770	EOL1	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.05667502139883729	[228]	[115]	0	hSpCas9	negative selection	11376634
32217096	32217119	18	+	28162770	EOL1	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	-0.9499213463456067	[21]	[5]	-6	hSpCas9	negative selection	11376635
32217080	32217103	18	+	28162770	MOLM13	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.3393452609235177	[304]	[278]	2	hSpCas9	negative selection	11545992
32217763	32217786	18	+	28162770	MOLM13	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	-0.28170382094937685	[152]	[90]	-2	hSpCas9	negative selection	11545993
32204275	32204298	18	-	28162770	MOLM13	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.27024362254381656	[288]	[251]	2	hSpCas9	negative selection	11545994
32208191	32208214	18	+	28162770	MOLM13	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	0.3110997822914004	[368]	[330]	2	hSpCas9	negative selection	11545995
32208211	32208234	18	+	28162770	MOLM13	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.15525288951103866	[502]	[404]	1	hSpCas9	negative selection	11545996
32210569	32210592	18	+	28162770	MOLM13	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.7285987344321286	[206]	[247]	5	hSpCas9	negative selection	11545997
32213178	32213201	18	+	28162770	MOLM13	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.18816378514217935	[538]	[443]	1	hSpCas9	negative selection	11545998
32215144	32215167	18	+	28162770	MOLM13	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	-0.2299264588664735	[411]	[253]	-1	hSpCas9	negative selection	11545999
32217033	32217056	18	-	28162770	MOLM13	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.8938186153281382	[238]	[92]	-5	hSpCas9	negative selection	11546000
32217096	32217119	18	+	28162770	MOLM13	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	0.3346228506811144	[33]	[30]	2	hSpCas9	negative selection	11546001
32217080	32217103	18	+	28162770	HEL	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.7052029189470104	[338]	[353]	6	hSpCas9	negative selection	11715358
32217763	32217786	18	+	28162770	HEL	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	0.3425058082123137	[164]	[133]	3	hSpCas9	negative selection	11715359
32204275	32204298	18	-	28162770	HEL	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.5675324878111832	[314]	[298]	5	hSpCas9	negative selection	11715360
32208191	32208214	18	+	28162770	HEL	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	-0.1142844145071027	[337]	[199]	-1	hSpCas9	negative selection	11715361
32208211	32208234	18	+	28162770	HEL	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.7417682079356562	[379]	[406]	6	hSpCas9	negative selection	11715362
32210569	32210592	18	+	28162770	HEL	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.7095078442130579	[189]	[198]	6	hSpCas9	negative selection	11715363
32213178	32213201	18	+	28162770	HEL	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.42143155177628655	[442]	[379]	3	hSpCas9	negative selection	11715364
32215144	32215167	18	+	28162770	HEL	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.9561274377212001	[304]	[378]	8	hSpCas9	negative selection	11715365
32217033	32217056	18	-	28162770	HEL	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.5580801773877393	[176]	[76]	-4	hSpCas9	negative selection	11715366
32217096	32217119	18	+	28162770	HEL	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	2.0635819529604067	[30]	[82]	9	hSpCas9	negative selection	11715367
32217080	32217103	18	+	28162770	MV411	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.7406574828763557	[210]	[296]	6	hSpCas9	negative selection	11884724
32217763	32217786	18	+	28162770	MV411	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	-0.5725837831109893	[142]	[80]	-4	hSpCas9	negative selection	11884725
32204275	32204298	18	-	28162770	MV411	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	-0.015596855051018543	[215]	[179]	0	hSpCas9	negative selection	11884726
32208191	32208214	18	+	28162770	MV411	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	1.628773834832897	[156]	[408]	9	hSpCas9	negative selection	11884727
32208211	32208234	18	+	28162770	MV411	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.9481970506033078	[346]	[563]	8	hSpCas9	negative selection	11884728
32210569	32210592	18	+	28162770	MV411	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	1.0171399313609815	[121]	[207]	8	hSpCas9	negative selection	11884729
32213178	32213201	18	+	28162770	MV411	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.319303536982096	[371]	[390]	3	hSpCas9	negative selection	11884730
32215144	32215167	18	+	28162770	MV411	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	1.1891108474079088	[264]	[508]	9	hSpCas9	negative selection	11884731
32217033	32217056	18	-	28162770	MV411	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	-0.5270027488020937	[129]	[75]	-4	hSpCas9	negative selection	11884732
32217096	32217119	18	+	28162770	MV411	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	1.9073621091851534	[24]	[78]	9	hSpCas9	negative selection	11884733
32217080	32217103	18	+	28162770	MONOMAC1	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.29216667085617154	[108]	[152]	3	hSpCas9	negative selection	12054090
32217763	32217786	18	+	28162770	MONOMAC1	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	-1.049479658645696	[64]	[35]	-7	hSpCas9	negative selection	12054091
32204275	32204298	18	-	28162770	MONOMAC1	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.14281315582507104	[127]	[161]	1	hSpCas9	negative selection	12054092
32208191	32208214	18	+	28162770	MONOMAC1	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	0.46761454229076227	[134]	[213]	4	hSpCas9	negative selection	12054093
32208211	32208234	18	+	28162770	MONOMAC1	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.5323155629967773	[265]	[440]	5	hSpCas9	negative selection	12054094
32210569	32210592	18	+	28162770	MONOMAC1	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	2.0323016398897575	[73]	[346]	9	hSpCas9	negative selection	12054095
32213178	32213201	18	+	28162770	MONOMAC1	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.9532057885210588	[286]	[636]	8	hSpCas9	negative selection	12054096
32215144	32215167	18	+	28162770	MONOMAC1	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	-0.241705896393282	[163]	[158]	-2	hSpCas9	negative selection	12054097
32217033	32217056	18	-	28162770	MONOMAC1	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	0.17981745833140228	[66]	[86]	1	hSpCas9	negative selection	12054098
32217096	32217119	18	+	28162770	MONOMAC1	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	-0.8070903287435405	[28]	[18]	-6	hSpCas9	negative selection	12054099
32217080	32217103	18	+	28162770	OCIAML2	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	0.9516031754408865	[24]	[267]	8	hSpCas9	negative selection	12223456
32217763	32217786	18	+	28162770	OCIAML2	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	0.6017786702858889	[16]	[142]	6	hSpCas9	negative selection	12223457
32204275	32204298	18	-	28162770	OCIAML2	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.0066919522910252605	[50]	[283]	0	hSpCas9	negative selection	12223458
32208191	32208214	18	+	28162770	OCIAML2	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	0.4774834330928703	[45]	[354]	4	hSpCas9	negative selection	12223459
32208211	32208234	18	+	28162770	OCIAML2	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	0.5026032651950534	[67]	[533]	5	hSpCas9	negative selection	12223460
32210569	32210592	18	+	28162770	OCIAML2	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	-0.2918266724533959	[35]	[162]	-2	hSpCas9	negative selection	12223461
32213178	32213201	18	+	28162770	OCIAML2	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.8079056741318206	[53]	[523]	7	hSpCas9	negative selection	12223462
32215144	32215167	18	+	28162770	OCIAML2	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.21449683740442693	[50]	[327]	2	hSpCas9	negative selection	12223463
32217033	32217056	18	-	28162770	OCIAML2	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	0.022410186037955637	[26]	[151]	0	hSpCas9	negative selection	12223464
32217096	32217119	18	+	28162770	OCIAML2	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	0.3367250968154427	[1]	[13]	3	hSpCas9	negative selection	12223465
32217080	32217103	18	+	28162770	OCIAML3	viability	GGTGTCTGCACTGTTCGAGATGG	MEP1B	ENSG00000141434	1.4630233047122159	[30]	[257]	9	hSpCas9	negative selection	12392822
32217763	32217786	18	+	28162770	OCIAML3	viability	GCCAGTCAGGGGAAGACTGGTGG	MEP1B	ENSG00000141434	-0.30860542146191494	[31]	[77]	-2	hSpCas9	negative selection	12392823
32204275	32204298	18	-	28162770	OCIAML3	viability	GCCAGAATCCCAGAGCGTGGAGG	MEP1B	ENSG00000141434	0.36792431884231724	[47]	[186]	3	hSpCas9	negative selection	12392824
32208191	32208214	18	+	28162770	OCIAML3	viability	GAGATAATGCTGACTGGCAACGG	MEP1B	ENSG00000141434	0.021651657619909503	[61]	[189]	0	hSpCas9	negative selection	12392825
32208211	32208234	18	+	28162770	OCIAML3	viability	CGGGTTTCACAGGTTCCCAGGGG	MEP1B	ENSG00000141434	-0.004383762233143962	[102]	[309]	0	hSpCas9	negative selection	12392826
32210569	32210592	18	+	28162770	OCIAML3	viability	AGAACGCTGTACCCTAAAAGAGG	MEP1B	ENSG00000141434	0.035348979755446486	[31]	[98]	0	hSpCas9	negative selection	12392827
32213178	32213201	18	+	28162770	OCIAML3	viability	GTGGTGTTTGAAGGACGCAAAGG	MEP1B	ENSG00000141434	0.6579107333154566	[113]	[542]	6	hSpCas9	negative selection	12392828
32215144	32215167	18	+	28162770	OCIAML3	viability	GGAACTCAGTTTAGAAGAGGTGG	MEP1B	ENSG00000141434	0.8151628519226843	[76]	[408]	7	hSpCas9	negative selection	12392829
32217033	32217056	18	-	28162770	OCIAML3	viability	GCAGAGGTCTTGAACACTAGGGG	MEP1B	ENSG00000141434	0.25244710142238125	[51]	[186]	2	hSpCas9	negative selection	12392830
32217096	32217119	18	+	28162770	OCIAML3	viability	GAGATGGCAAAGCTGAGTGCAGG	MEP1B	ENSG00000141434	-0.47853042290422687	[5]	[12]	-4	hSpCas9	negative selection	12392831