| 100471742 | 100471765 | 9 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GAGTTTCGCTCTTGTTGCCCAAG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.7837275452001344 | [95,22] | [7,5] | -4 | dCas9-VP64 | positive selection | 2394487 | 100471742 | 100471765 | 9 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GAGTTTCGCTCTTGTTGCCCAAG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.16320683952806103 | [88,58] | [29,12] | -1 | dCas9-VP64 | positive selection | 2489742 | 100445199 | 100445222 | 9 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.08191132599226135 | [3] | [1,2] | -2 | hSpCas9 | positive selection | 4153090 | 100442345 | 100442368 | 9 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GGAACGGATACCTTGGGCTGAGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.031099939916425623 | [4] | [2,3] | 0 | hSpCas9 | positive selection | 4153091 | 100450616 | 100450639 | 9 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.19966240117494188 | [4] | [2,3] | 5 | hSpCas9 | positive selection | 4153092 | 100445212 | 100445235 | 9 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.1373571844615008 | [1] | [1,0] | 3 | hSpCas9 | positive selection | 4153093 | 100450698 | 100450721 | 9 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TTTTAAAGCACCTTCCTGAGAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.07221628294659779 | [3] | [3,2] | 1 | hSpCas9 | positive selection | 4153094 | 100445199 | 100445222 | 9 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 1.0946986004317967 | [3] | [3,3,1,3] | 8 | hSpCas9 | positive selection | 4217112 | 100442345 | 100442368 | 9 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GGAACGGATACCTTGGGCTGAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.7494547565041286 | [3] | [1,1,1,2] | 5 | hSpCas9 | positive selection | 4217113 | 100450616 | 100450639 | 9 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.38856140418535307 | [2] | [3,0,2,0] | 3 | hSpCas9 | positive selection | 4217114 | 100445212 | 100445235 | 9 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.7803394739816059 | [0] | [0,2,0,0] | 5 | hSpCas9 | positive selection | 4217115 | 100450698 | 100450721 | 9 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TTTTAAAGCACCTTCCTGAGAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.993645180288919 | [5] | [1,4,3,4] | 7 | hSpCas9 | positive selection | 4217116 | 100450616 | 100450639 | 9 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.4218309487142661 | [2] | [2,0] | -7 | hSpCas9 | positive selection | 4283834 | 100450953 | 100450976 | 9 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.13075038458933216 | [2] | [3,1] | 2 | hSpCas9 | positive selection | 4348090 | 100445212 | 100445235 | 9 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.07032459954452956 | [2] | [2,1] | 1 | hSpCas9 | positive selection | 4348091 | 100445199 | 100445222 | 9 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.48074974514172164 | [3] | [4,4] | 8 | hSpCas9 | positive selection | 4348092 | 100442351 | 100442374 | 9 | - | 27661255 | K562 | viability | GCATCAGGAACGGATACCTTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.13253679701767807 | [1052,1263] | [1164,879] | 4 | dCas9-KRAB | negative selection | 5494389 | 100450616 | 100450639 | 9 | - | 27260156 | BXPC3 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.014479064291358923 | [334] | [264,287,432,421] | 0 | hSpCas9 | negative selection | 5556294 | 100450953 | 100450976 | 9 | - | 27260156 | BXPC3 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.24227035716284878 | [322] | [386,357,437,418] | 5 | hSpCas9 | negative selection | 5620550 | 100445212 | 100445235 | 9 | - | 27260156 | BXPC3 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.17462076305238525 | [445] | [547,460,533,564] | 4 | hSpCas9 | negative selection | 5620551 | 100445199 | 100445222 | 9 | + | 27260156 | BXPC3 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.15238056047653847 | [743] | [906,613,1074,870] | 3 | hSpCas9 | negative selection | 5620552 | 100450616 | 100450639 | 9 | - | 27260156 | A673 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.061133890084540454 | [334] | [424,460,382,407] | 1 | hSpCas9 | negative selection | 5677545 | 100450953 | 100450976 | 9 | - | 27260156 | A673 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.14974869173256405 | [322] | [503,400,463,355] | 3 | hSpCas9 | negative selection | 5741801 | 100445212 | 100445235 | 9 | - | 27260156 | A673 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.36310244001647396 | [445] | [725,693,638,699] | 8 | hSpCas9 | negative selection | 5741802 | 100445199 | 100445222 | 9 | + | 27260156 | A673 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.19525202079456028 | [743] | [1259,939,938,977] | 4 | hSpCas9 | negative selection | 5741803 | 100450616 | 100450639 | 9 | - | 27260156 | A375 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.3521462629064119 | [334] | [493,655,482,396] | 5 | hSpCas9 | negative selection | 5798796 | 100450953 | 100450976 | 9 | - | 27260156 | A375 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.5411314085459599 | [322] | [654,712,417,443] | 7 | hSpCas9 | negative selection | 5863052 | 100445212 | 100445235 | 9 | - | 27260156 | A375 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.5449506855503738 | [445] | [743,810,626,850] | 7 | hSpCas9 | negative selection | 5863053 | 100445199 | 100445222 | 9 | + | 27260156 | A375 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.26713958642981916 | [743] | [1115,1159,805,1105] | 4 | hSpCas9 | negative selection | 5863054 | 100450616 | 100450639 | 9 | - | 27260156 | COLO741 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.0929197942247178 | [334] | [369,543,447] | 2 | hSpCas9 | negative selection | 5920047 | 100450953 | 100450976 | 9 | - | 27260156 | COLO741 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.17586836515773407 | [322] | [328,587,468] | 4 | hSpCas9 | negative selection | 5984303 | 100445212 | 100445235 | 9 | - | 27260156 | COLO741 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.2575233043071583 | [445] | [798,656,601] | 5 | hSpCas9 | negative selection | 5984304 | 100445199 | 100445222 | 9 | + | 27260156 | COLO741 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.18515009488997192 | [743] | [1218,1057,981] | 4 | hSpCas9 | negative selection | 5984305 | 100450616 | 100450639 | 9 | - | 27260156 | CAL120 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.5451169890647656 | [334] | [813,739,306] | 7 | hSpCas9 | negative selection | 6041298 | 100450953 | 100450976 | 9 | - | 27260156 | CAL120 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.3223044107669978 | [322] | [621,600,305] | 5 | hSpCas9 | negative selection | 6105554 | 100445212 | 100445235 | 9 | - | 27260156 | CAL120 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.10141209644508835 | [445] | [453,842,469] | 1 | hSpCas9 | negative selection | 6105555 | 100445199 | 100445222 | 9 | + | 27260156 | CAL120 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.05433174215372727 | [743] | [955,1140,788] | 0 | hSpCas9 | negative selection | 6105556 | 100450616 | 100450639 | 9 | - | 27260156 | CADOES1 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.11899684767535845 | [334] | [264,401,242,235] | -2 | hSpCas9 | negative selection | 6162549 | 100450953 | 100450976 | 9 | - | 27260156 | CADOES1 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.358760863057799 | [322] | [385,449,447,251] | 6 | hSpCas9 | negative selection | 6226805 | 100445212 | 100445235 | 9 | - | 27260156 | CADOES1 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.5155163924515008 | [445] | [632,507,575,656] | 8 | hSpCas9 | negative selection | 6226806 | 100445199 | 100445222 | 9 | + | 27260156 | CADOES1 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.3156096698041382 | [743] | [941,806,843,850] | 5 | hSpCas9 | negative selection | 6226807 | 100450616 | 100450639 | 9 | - | 27260156 | EWS502 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.561030722491532 | [334] | [482,354,660,612] | 8 | hSpCas9 | negative selection | 6283800 | 100450953 | 100450976 | 9 | - | 27260156 | EWS502 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.30028962710011653 | [322] | [289,580,425,393] | 5 | hSpCas9 | negative selection | 6348056 | 100445212 | 100445235 | 9 | - | 27260156 | EWS502 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.5440119654819227 | [445] | [703,805,620,607] | 8 | hSpCas9 | negative selection | 6348057 | 100445199 | 100445222 | 9 | + | 27260156 | EWS502 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.32519281170521874 | [743] | [814,1007,1183,958] | 6 | hSpCas9 | negative selection | 6348058 | 100450616 | 100450639 | 9 | - | 27260156 | EW8 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.01743500052988306 | [334] | [280,314,294,204] | 0 | hSpCas9 | negative selection | 6405051 | 100450953 | 100450976 | 9 | - | 27260156 | EW8 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.27571688407317 | [322] | [496,279,206,320] | 5 | hSpCas9 | negative selection | 6469307 | 100445212 | 100445235 | 9 | - | 27260156 | EW8 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.40950615558153747 | [445] | [511,538,467,405] | 7 | hSpCas9 | negative selection | 6469308 | 100445199 | 100445222 | 9 | + | 27260156 | EW8 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.17420913411049221 | [743] | [657,759,520,804] | 3 | hSpCas9 | negative selection | 6469309 | 100450616 | 100450639 | 9 | - | 27260156 | CORL105 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.11247528510901977 | [334] | [459,409,502,336] | 2 | hSpCas9 | negative selection | 6526302 | 100450953 | 100450976 | 9 | - | 27260156 | CORL105 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.26224356696750833 | [322] | [491,524,401,386] | 5 | hSpCas9 | negative selection | 6590558 | 100445212 | 100445235 | 9 | - | 27260156 | CORL105 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.7704907395597594 | [445] | [849,995,820,880] | 9 | hSpCas9 | negative selection | 6590559 | 100445199 | 100445222 | 9 | + | 27260156 | CORL105 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.12299877758824207 | [743] | [934,838,1111,934] | 2 | hSpCas9 | negative selection | 6590560 | 100450616 | 100450639 | 9 | - | 27260156 | HS294T | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.10609146358457211 | [334] | [145,83,97,157] | -1 | hSpCas9 | negative selection | 6647553 | 100450953 | 100450976 | 9 | - | 27260156 | HS294T | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 1.0780559348765841 | [322] | [352,169,137,411] | 9 | hSpCas9 | negative selection | 6711809 | 100445212 | 100445235 | 9 | - | 27260156 | HS294T | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.33048048534979746 | [445] | [247,195,174,250] | 4 | hSpCas9 | negative selection | 6711810 | 100445199 | 100445222 | 9 | + | 27260156 | HS294T | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.20544311786573943 | [743] | [291,420,278,334] | 2 | hSpCas9 | negative selection | 6711811 | 100450616 | 100450639 | 9 | - | 27260156 | HCC44 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.25939445419651663 | [334] | [337,275,652,587] | 4 | hSpCas9 | negative selection | 6768804 | 100450953 | 100450976 | 9 | - | 27260156 | HCC44 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.4283301901161178 | [322] | [472,281,514,716] | 7 | hSpCas9 | negative selection | 6833060 | 100445212 | 100445235 | 9 | - | 27260156 | HCC44 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.3605264375786608 | [445] | [693,515,818,609] | 6 | hSpCas9 | negative selection | 6833061 | 100445199 | 100445222 | 9 | + | 27260156 | HCC44 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.32060320975305723 | [743] | [1117,1128,1196,779] | 5 | hSpCas9 | negative selection | 6833062 | 100450616 | 100450639 | 9 | - | 27260156 | G402 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.3152013770441844 | [334] | [408,260,457,198] | -4 | hSpCas9 | negative selection | 6890055 | 100450953 | 100450976 | 9 | - | 27260156 | G402 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.49356418525107154 | [322] | [280,580,838,481] | 6 | hSpCas9 | negative selection | 6954311 | 100445212 | 100445235 | 9 | - | 27260156 | G402 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.8288925347165709 | [445] | [1385,1045,864,646] | 8 | hSpCas9 | negative selection | 6954312 | 100445199 | 100445222 | 9 | + | 27260156 | G402 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.5705654355433504 | [743] | [1192,828,1560,1732] | 7 | hSpCas9 | negative selection | 6954313 | 100450616 | 100450639 | 9 | - | 27260156 | L33 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.05872347774812925 | [334] | [311,105,208,382] | -1 | hSpCas9 | negative selection | 7011306 | 100450953 | 100450976 | 9 | - | 27260156 | L33 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.11782093152554496 | [322] | [301,127,154,328] | -3 | hSpCas9 | negative selection | 7075562 | 100445212 | 100445235 | 9 | - | 27260156 | L33 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.2885822276487562 | [445] | [527,224,334,568] | 6 | hSpCas9 | negative selection | 7075563 | 100445199 | 100445222 | 9 | + | 27260156 | L33 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.2438218703911137 | [743] | [632,278,361,622] | -5 | hSpCas9 | negative selection | 7075564 | 100450616 | 100450639 | 9 | - | 27260156 | K562 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.3359957774097616 | [334] | [325,414,225,513] | 4 | hSpCas9 | negative selection | 7132557 | 100450953 | 100450976 | 9 | - | 27260156 | K562 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.15075553001302477 | [322] | [543,526,166,89] | 1 | hSpCas9 | negative selection | 7196813 | 100445212 | 100445235 | 9 | - | 27260156 | K562 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.5184726786651448 | [445] | [756,650,542,358] | 6 | hSpCas9 | negative selection | 7196814 | 100445199 | 100445222 | 9 | + | 27260156 | K562 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.5115854481234142 | [743] | [704,1392,863,817] | 6 | hSpCas9 | negative selection | 7196815 | 100450616 | 100450639 | 9 | - | 27260156 | HT29 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.029410189459006753 | [334] | [463,373,403,358] | 0 | hSpCas9 | negative selection | 7253808 | 100450953 | 100450976 | 9 | - | 27260156 | HT29 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.2776825977039351 | [322] | [381,599,491,434] | 5 | hSpCas9 | negative selection | 7318064 | 100445212 | 100445235 | 9 | - | 27260156 | HT29 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.47765263911423717 | [445] | [725,930,568,795] | 8 | hSpCas9 | negative selection | 7318065 | 100445199 | 100445222 | 9 | + | 27260156 | HT29 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.33784743233487335 | [743] | [1465,1016,1194,926] | 6 | hSpCas9 | negative selection | 7318066 | 100450616 | 100450639 | 9 | - | 27260156 | MHHES1 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.1607476477955876 | [334] | [537,418,375,369] | 3 | hSpCas9 | negative selection | 7375059 | 100450953 | 100450976 | 9 | - | 27260156 | MHHES1 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.12129712172277918 | [322] | [436,381,559,236] | 2 | hSpCas9 | negative selection | 7439315 | 100445212 | 100445235 | 9 | - | 27260156 | MHHES1 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.5907658650334086 | [445] | [821,740,652,789] | 8 | hSpCas9 | negative selection | 7439316 | 100445199 | 100445222 | 9 | + | 27260156 | MHHES1 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.05790384638880863 | [743] | [1108,635,1021,738] | 1 | hSpCas9 | negative selection | 7439317 | 100450616 | 100450639 | 9 | - | 27260156 | MEWO | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.4442781491210628 | [334] | [178,236,264] | -7 | hSpCas9 | negative selection | 7496310 | 100450953 | 100450976 | 9 | - | 27260156 | MEWO | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.01697218279421797 | [322] | [302,240,372] | 0 | hSpCas9 | negative selection | 7560566 | 100445212 | 100445235 | 9 | - | 27260156 | MEWO | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.19172976917410656 | [445] | [686,345,437] | 4 | hSpCas9 | negative selection | 7560567 | 100445199 | 100445222 | 9 | + | 27260156 | MEWO | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.1945073986295836 | [743] | [688,669,480] | -4 | hSpCas9 | negative selection | 7560568 | 100450616 | 100450639 | 9 | - | 27260156 | LNCAPCLONEFGC | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.0659492289551668 | [334] | [383,258,283,340] | 1 | hSpCas9 | negative selection | 7617561 | 100450953 | 100450976 | 9 | - | 27260156 | LNCAPCLONEFGC | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.7185263460778097 | [322] | [563,444,384,517] | 9 | hSpCas9 | negative selection | 7681817 | 100445212 | 100445235 | 9 | - | 27260156 | LNCAPCLONEFGC | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.4594817170828436 | [445] | [548,390,765,557] | 7 | hSpCas9 | negative selection | 7681818 | 100445199 | 100445222 | 9 | + | 27260156 | LNCAPCLONEFGC | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.4954127559877749 | [743] | [739,813,1348,968] | 7 | hSpCas9 | negative selection | 7681819 | 100450616 | 100450639 | 9 | - | 27260156 | PANC0327 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.10109029830159927 | [334] | [443,124,374,367] | 1 | hSpCas9 | negative selection | 7738812 | 100450953 | 100450976 | 9 | - | 27260156 | PANC0327 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.32815161443033236 | [322] | [399,266,376,411] | 5 | hSpCas9 | negative selection | 7803068 | 100445212 | 100445235 | 9 | - | 27260156 | PANC0327 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.24124574598611884 | [445] | [635,295,463,512] | 3 | hSpCas9 | negative selection | 7803069 | 100445199 | 100445222 | 9 | + | 27260156 | PANC0327 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.09485622129948812 | [743] | [1040,591,559,671] | 1 | hSpCas9 | negative selection | 7803070 | 100450616 | 100450639 | 9 | - | 27260156 | NCIH2009 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.5236537930679167 | [334] | [948,618,504] | 7 | hSpCas9 | negative selection | 7860063 | 100450953 | 100450976 | 9 | - | 27260156 | NCIH2009 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.12347533789522647 | [322] | [331,459,432] | -2 | hSpCas9 | negative selection | 7924319 | 100445212 | 100445235 | 9 | - | 27260156 | NCIH2009 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.43430502704738344 | [445] | [914,843,779] | 6 | hSpCas9 | negative selection | 7924320 | 100445199 | 100445222 | 9 | + | 27260156 | NCIH2009 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.29971113020772466 | [743] | [1503,1262,1113] | 4 | hSpCas9 | negative selection | 7924321 | 100450616 | 100450639 | 9 | - | 27260156 | NCIH1373 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.6639106459412105 | [334] | [823,780,225,148] | 6 | hSpCas9 | negative selection | 7981314 | 100450953 | 100450976 | 9 | - | 27260156 | NCIH1373 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.6353193767623316 | [322] | [712,491,394,180] | 6 | hSpCas9 | negative selection | 8045570 | 100445212 | 100445235 | 9 | - | 27260156 | NCIH1373 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.33638052775606714 | [445] | [661,294,707,239] | 3 | hSpCas9 | negative selection | 8045571 | 100445199 | 100445222 | 9 | + | 27260156 | NCIH1373 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.504954966941702 | [743] | [1692,1291,630,312] | 5 | hSpCas9 | negative selection | 8045572 | 100450616 | 100450639 | 9 | - | 27260156 | PATU8902 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.17815181434707278 | [334] | [391,427,602,684] | 1 | hSpCas9 | negative selection | 8102565 | 100450953 | 100450976 | 9 | - | 27260156 | PATU8902 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.6621100185257341 | [322] | [642,1028,382,895] | 7 | hSpCas9 | negative selection | 8166821 | 100445212 | 100445235 | 9 | - | 27260156 | PATU8902 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.9076733093395454 | [445] | [1139,1176,1094,1270] | 8 | hSpCas9 | negative selection | 8166822 | 100445199 | 100445222 | 9 | + | 27260156 | PATU8902 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.47774090419842674 | [743] | [1430,1189,966,2410] | 5 | hSpCas9 | negative selection | 8166823 | 100450616 | 100450639 | 9 | - | 27260156 | PANC1 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.1454788659549972 | [334] | [290,316,366,296] | 2 | hSpCas9 | negative selection | 8223816 | 100450953 | 100450976 | 9 | - | 27260156 | PANC1 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.34760628483165557 | [322] | [275,439,404,311] | 5 | hSpCas9 | negative selection | 8288072 | 100445212 | 100445235 | 9 | - | 27260156 | PANC1 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.44897991036629664 | [445] | [520,814,460,370] | 7 | hSpCas9 | negative selection | 8288073 | 100445199 | 100445222 | 9 | + | 27260156 | PANC1 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.39659093703009896 | [743] | [760,1184,1001,528] | 6 | hSpCas9 | negative selection | 8288074 | 100450616 | 100450639 | 9 | - | 27260156 | PANC0813 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.32310838123443986 | [334] | [550,482,420,516] | 5 | hSpCas9 | negative selection | 8345067 | 100450953 | 100450976 | 9 | - | 27260156 | PANC0813 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.12185969115085538 | [322] | [359,299,379,354] | -2 | hSpCas9 | negative selection | 8409323 | 100445212 | 100445235 | 9 | - | 27260156 | PANC0813 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.4371975203993874 | [445] | [869,557,625,791] | 7 | hSpCas9 | negative selection | 8409324 | 100445199 | 100445222 | 9 | + | 27260156 | PANC0813 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.11519911996581234 | [743] | [1050,926,1091,736] | 2 | hSpCas9 | negative selection | 8409325 | 100450616 | 100450639 | 9 | - | 27260156 | RDES | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.20053907198228998 | [334] | [416,365,359,655] | 3 | hSpCas9 | negative selection | 8466318 | 100450953 | 100450976 | 9 | - | 27260156 | RDES | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.3012579114270775 | [322] | [382,509,498,432] | 5 | hSpCas9 | negative selection | 8530574 | 100445212 | 100445235 | 9 | - | 27260156 | RDES | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.4655283246688101 | [445] | [572,740,790,739] | 7 | hSpCas9 | negative selection | 8530575 | 100445199 | 100445222 | 9 | + | 27260156 | RDES | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.44891186122174964 | [743] | [941,984,1295,1542] | 7 | hSpCas9 | negative selection | 8530576 | 100450616 | 100450639 | 9 | - | 27260156 | PC3 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.18343105169303037 | [334] | [282,282,578,457] | 4 | hSpCas9 | negative selection | 8587569 | 100450953 | 100450976 | 9 | - | 27260156 | PC3 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.12945521723748488 | [322] | [229,301,433,501] | 3 | hSpCas9 | negative selection | 8651825 | 100445212 | 100445235 | 9 | - | 27260156 | PC3 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.19550144750058118 | [445] | [252,525,955,547] | 4 | hSpCas9 | negative selection | 8651826 | 100445199 | 100445222 | 9 | + | 27260156 | PC3 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.23486514768852118 | [743] | [462,517,1084,641] | -5 | hSpCas9 | negative selection | 8651827 | 100450616 | 100450639 | 9 | - | 27260156 | PATU8988T | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.18744040128324413 | [334] | [319,275,291,244] | -3 | hSpCas9 | negative selection | 8708820 | 100450953 | 100450976 | 9 | - | 27260156 | PATU8988T | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.3539794458528862 | [322] | [564,421,314,287] | 6 | hSpCas9 | negative selection | 8773076 | 100445212 | 100445235 | 9 | - | 27260156 | PATU8988T | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.23977087307557343 | [445] | [565,634,384,458] | 4 | hSpCas9 | negative selection | 8773077 | 100445199 | 100445222 | 9 | + | 27260156 | PATU8988T | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.2996331782270977 | [743] | [1004,896,855,773] | 5 | hSpCas9 | negative selection | 8773078 | 100450616 | 100450639 | 9 | - | 27260156 | T47D | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.2189719675209369 | [334] | [504,417,449,446] | 4 | hSpCas9 | negative selection | 8830071 | 100450953 | 100450976 | 9 | - | 27260156 | T47D | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.3933610136555947 | [322] | [555,478,430,513] | 8 | hSpCas9 | negative selection | 8894327 | 100445212 | 100445235 | 9 | - | 27260156 | T47D | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.47418508200527754 | [445] | [711,532,829,829] | 8 | hSpCas9 | negative selection | 8894328 | 100445199 | 100445222 | 9 | + | 27260156 | T47D | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.3267525472077055 | [743] | [1039,996,1214,1101] | 7 | hSpCas9 | negative selection | 8894329 | 100450616 | 100450639 | 9 | - | 27260156 | SU8686 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.06877942399621972 | [334] | [267,374,450,296] | 1 | hSpCas9 | negative selection | 8951322 | 100450953 | 100450976 | 9 | - | 27260156 | SU8686 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.37194365068695 | [322] | [319,378,535,442] | 6 | hSpCas9 | negative selection | 9015578 | 100445212 | 100445235 | 9 | - | 27260156 | SU8686 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.2813613813200847 | [445] | [490,445,593,651] | 5 | hSpCas9 | negative selection | 9015579 | 100445199 | 100445222 | 9 | + | 27260156 | SU8686 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.1661171429100583 | [743] | [568,603,1007,1256] | 3 | hSpCas9 | negative selection | 9015580 | 100450616 | 100450639 | 9 | - | 27260156 | SKES1 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.013920378101328512 | [334] | [456,397,222,275] | 0 | hSpCas9 | negative selection | 9072573 | 100450953 | 100450976 | 9 | - | 27260156 | SKES1 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.023158553745502464 | [322] | [392,328,263,329] | 0 | hSpCas9 | negative selection | 9136829 | 100445212 | 100445235 | 9 | - | 27260156 | SKES1 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.31340705435562166 | [445] | [653,749,499,362] | 6 | hSpCas9 | negative selection | 9136830 | 100445199 | 100445222 | 9 | + | 27260156 | SKES1 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.04669114841667288 | [743] | [742,790,774,584] | -1 | hSpCas9 | negative selection | 9136831 | 100450616 | 100450639 | 9 | - | 27260156 | TOV112D | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.10622276635145189 | [334] | [449,397,411,204] | 2 | hSpCas9 | negative selection | 9193824 | 100450953 | 100450976 | 9 | - | 27260156 | TOV112D | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.24561317582124675 | [322] | [466,545,236,331] | 5 | hSpCas9 | negative selection | 9258080 | 100445212 | 100445235 | 9 | - | 27260156 | TOV112D | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.37455854325687254 | [445] | [585,474,706,523] | 7 | hSpCas9 | negative selection | 9258081 | 100445199 | 100445222 | 9 | + | 27260156 | TOV112D | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.23729064086799978 | [743] | [739,942,944,887] | 4 | hSpCas9 | negative selection | 9258082 | 100450616 | 100450639 | 9 | - | 27260156 | TC71 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.26094923969014716 | [334] | [430,370,439,481] | 6 | hSpCas9 | negative selection | 9315075 | 100450953 | 100450976 | 9 | - | 27260156 | TC71 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.059403011123264515 | [322] | [334,310,373,305] | -1 | hSpCas9 | negative selection | 9379331 | 100445212 | 100445235 | 9 | - | 27260156 | TC71 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.3573223794385708 | [445] | [708,716,594,414] | 8 | hSpCas9 | negative selection | 9379332 | 100445199 | 100445222 | 9 | + | 27260156 | TC71 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.2088019171812926 | [743] | [888,960,942,891] | 5 | hSpCas9 | negative selection | 9379333 | 100450616 | 100450639 | 9 | - | 27260156 | TC32 | viability | TGAGAGGTCCCCTCACATACTGG | MSANTD3-TMEFF1 | ENSG00000251349 | -0.22753171090798574 | [334] | [229,157,383,360] | -4 | hSpCas9 | negative selection | 9436326 | 100450953 | 100450976 | 9 | - | 27260156 | TC32 | viability | CCCAAAGTCTTAGGGCGAATTGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.5202280502787052 | [322] | [536,204,639,444] | 8 | hSpCas9 | negative selection | 9500582 | 100445212 | 100445235 | 9 | - | 27260156 | TC32 | viability | TTTCCTACCAAGTCCCAGAAAGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.3341676614905606 | [445] | [458,435,780,490] | 6 | hSpCas9 | negative selection | 9500583 | 100445199 | 100445222 | 9 | + | 27260156 | TC32 | viability | AATTGTCAATCATCCTTTCTGGG | MSANTD3-TMEFF1 | ENSG00000251349 | 0.4704927619499165 | [743] | [748,978,1224,925] | 7 | hSpCas9 | negative selection | 9500584 |