Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:124540
• Symbol:MSI2
• Description:musashi RNA binding protein 2

DataSource: http://genomecrispr.dkfz.de/#!/results/MSI2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
57529703	57529726	17	+	26472758	Jiyoye	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.6377883096472898	[149]	[175]	4	hSpCas9	negative selection	102858
57615995	57616018	17	+	26472758	Jiyoye	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.740074594214239	[654]	[824]	5	hSpCas9	negative selection	102859
57627257	57627280	17	-	26472758	Jiyoye	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	1.0238467419543678	[74]	[114]	6	hSpCas9	negative selection	102860
57401414	57401437	17	+	26472758	Jiyoye	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.3236688171847044	[568]	[536]	2	hSpCas9	negative selection	102861
57258330	57258353	17	-	26472758	Jiyoye	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.5379945919505946	[589]	[645]	4	hSpCas9	negative selection	102862
57262171	57262194	17	+	26472758	Jiyoye	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	1.5358430454703489	[133]	[292]	8	hSpCas9	negative selection	102863
57616009	57616032	17	-	26472758	Jiyoye	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	0.7880801958655714	[138]	[180]	5	hSpCas9	negative selection	102864
57616032	57616055	17	+	26472758	Jiyoye	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	0.8412712166004018	[93]	[126]	6	hSpCas9	negative selection	102865
57616053	57616076	17	+	26472758	Jiyoye	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.44082152504907657	[107]	[59]	-3	hSpCas9	negative selection	102866
57401450	57401473	17	+	26472758	Jiyoye	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	0.6682212342462133	[120]	[144]	5	hSpCas9	negative selection	102867
57529703	57529726	17	+	26472758	KBM7	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.224639480182048	[408,378]	[269,168]	2	hSpCas9	negative selection	293976
57615995	57616018	17	+	26472758	KBM7	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.5173966887289794	[2600,2252]	[1782,1491]	5	hSpCas9	negative selection	293977
57627257	57627280	17	-	26472758	KBM7	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	0.2749204404403195	[335,189]	[181,113]	3	hSpCas9	negative selection	293978
57401414	57401437	17	+	26472758	KBM7	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.033134046199813305	[1674,1722]	[801,770]	0	hSpCas9	negative selection	293979
57258330	57258353	17	-	26472758	KBM7	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	-0.34788807954408374	[1608,1688]	[647,582]	-3	hSpCas9	negative selection	293980
57262171	57262194	17	+	26472758	KBM7	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.0019440955536524362	[643,573]	[381,200]	0	hSpCas9	negative selection	293981
57616009	57616032	17	-	26472758	KBM7	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	-0.19608276483514886	[841,595]	[255,322]	-2	hSpCas9	negative selection	293982
57616032	57616055	17	+	26472758	KBM7	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	0.43118872092174787	[404,439]	[311,232]	4	hSpCas9	negative selection	293983
57616053	57616076	17	+	26472758	KBM7	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.06415332666610038	[468,347]	[118,237]	0	hSpCas9	negative selection	293984
57401450	57401473	17	+	26472758	KBM7	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	0.24653635327079457	[414,473]	[168,323]	2	hSpCas9	negative selection	293985
57529703	57529726	17	+	26472758	Raji	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.3389748935565122	[200]	[58]	3	hSpCas9	negative selection	485094
57615995	57616018	17	+	26472758	Raji	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.34371514766792144	[1235]	[363]	3	hSpCas9	negative selection	485095
57627257	57627280	17	-	26472758	Raji	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	0.7916076674678323	[116]	[46]	7	hSpCas9	negative selection	485096
57401414	57401437	17	+	26472758	Raji	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.39833068692779916	[545]	[166]	4	hSpCas9	negative selection	485097
57258330	57258353	17	-	26472758	Raji	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.04061452316089875	[795]	[189]	0	hSpCas9	negative selection	485098
57262171	57262194	17	+	26472758	Raji	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.5960438977956233	[190]	[66]	5	hSpCas9	negative selection	485099
57616009	57616032	17	-	26472758	Raji	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	-0.4255567529992744	[462]	[79]	-3	hSpCas9	negative selection	485100
57616032	57616055	17	+	26472758	Raji	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	0.21429873929011142	[233]	[62]	2	hSpCas9	negative selection	485101
57616053	57616076	17	+	26472758	Raji	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.9470642486487769	[215]	[25]	-6	hSpCas9	negative selection	485102
57401450	57401473	17	+	26472758	Raji	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	0.032615766971627186	[197]	[46]	0	hSpCas9	negative selection	485103
57529703	57529726	17	+	26472758	K562	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.34897465870903654	[305]	[328]	2	hSpCas9	negative selection	676212
57615995	57616018	17	+	26472758	K562	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.4995658188817842	[1772]	[2115]	4	hSpCas9	negative selection	676213
57627257	57627280	17	-	26472758	K562	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	0.19319340431127374	[257]	[248]	1	hSpCas9	negative selection	676214
57401414	57401437	17	+	26472758	K562	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.026850543305605656	[1442]	[1240]	0	hSpCas9	negative selection	676215
57258330	57258353	17	-	26472758	K562	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.7825912683884952	[1242]	[1804]	6	hSpCas9	negative selection	676216
57262171	57262194	17	+	26472758	K562	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.4025665613324057	[491]	[548]	3	hSpCas9	negative selection	676217
57616009	57616032	17	-	26472758	K562	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	0.293144767482868	[523]	[541]	2	hSpCas9	negative selection	676218
57616032	57616055	17	+	26472758	K562	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	0.029405836695596377	[259]	[223]	0	hSpCas9	negative selection	676219
57616053	57616076	17	+	26472758	K562	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.0300622048184552	[328]	[271]	0	hSpCas9	negative selection	676220
57401450	57401473	17	+	26472758	K562	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	0.6921369257399536	[370]	[505]	6	hSpCas9	negative selection	676221
57256782	57256805	17	+	26627737	DLD1	viability	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-0.209667084532753	[501]	[221,108,82]	-2	hSpCas9	negative selection	798984
57257103	57257126	17	+	26627737	DLD1	viability	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	0.31527973909948703	[309]	[221,124,28]	3	hSpCas9	negative selection	798985
57262171	57262194	17	+	26627737	DLD1	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.15028502262847643	[708]	[207,244,154]	-1	hSpCas9	negative selection	798986
57616053	57616076	17	+	26627737	DLD1	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.10166467715042629	[437]	[142,174,74]	-1	hSpCas9	negative selection	798988
57627240	57627263	17	+	26627737	DLD1	viability	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.4054276848902083	[1585]	[720,961,347]	4	hSpCas9	negative selection	798989
57652106	57652129	17	+	26627737	DLD1	viability	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	1.4273155917267588	[314]	[243,318,237]	9	hSpCas9	negative selection	798990
57256782	57256805	17	+	26627737	GBM cells	viability after 5 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-0.032138771396822974	[142]	[50,98]	0	hSpCas9	negative selection	881299
57257103	57257126	17	+	26627737	GBM cells	viability after 5 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-1.787928239854684	[131]	[16,23]	-9	hSpCas9	negative selection	881300
57262171	57262194	17	+	26627737	GBM cells	viability after 5 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.465049439798889	[295]	[137,91]	-6	hSpCas9	negative selection	881301
57616053	57616076	17	+	26627737	GBM cells	viability after 5 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.4605250149011708	[262]	[112,91]	-6	hSpCas9	negative selection	881303
57627240	57627263	17	+	26627737	GBM cells	viability after 5 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.23717691176452127	[684]	[441,423]	4	hSpCas9	negative selection	881304
57652106	57652129	17	+	26627737	GBM cells	viability after 5 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.7608163942374426	[296]	[80,106]	-8	hSpCas9	negative selection	881305
57256782	57256805	17	+	26627737	GBM cells	viability after 13 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-0.08518529314989731	[142]	[76,69]	-1	hSpCas9	negative selection	963614
57257103	57257126	17	+	26627737	GBM cells	viability after 13 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-1.02605376104404	[131]	[27,40]	-8	hSpCas9	negative selection	963615
57262171	57262194	17	+	26627737	GBM cells	viability after 13 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.9863220479685963	[295]	[74,85]	-8	hSpCas9	negative selection	963616
57616053	57616076	17	+	26627737	GBM cells	viability after 13 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.8872766146992104	[262]	[96,60]	-8	hSpCas9	negative selection	963618
57627240	57627263	17	+	26627737	GBM cells	viability after 13 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.12245350500700991	[684]	[483,339]	1	hSpCas9	negative selection	963619
57652106	57652129	17	+	26627737	GBM cells	viability after 13 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.6524254515568919	[296]	[112,93]	-6	hSpCas9	negative selection	963620
57256782	57256805	17	+	26627737	GBM cells	viability after 21 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	0.0938555113243742	[142]	[84,80]	1	hSpCas9	negative selection	1045929
57257103	57257126	17	+	26627737	GBM cells	viability after 21 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-3.253001892497473	[131]	[6,7]	-9	hSpCas9	negative selection	1045930
57262171	57262194	17	+	26627737	GBM cells	viability after 21 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-1.926634307780704	[295]	[46,37]	-8	hSpCas9	negative selection	1045931
57616053	57616076	17	+	26627737	GBM cells	viability after 21 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-1.1257522351547118	[262]	[65,64]	-7	hSpCas9	negative selection	1045933
57627240	57627263	17	+	26627737	GBM cells	viability after 21 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.08711781747061975	[684]	[434,358]	0	hSpCas9	negative selection	1045934
57652106	57652129	17	+	26627737	GBM cells	viability after 21 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.710407513348013	[296]	[95,100]	-6	hSpCas9	negative selection	1045935
57256782	57256805	17	+	26627737	RPE1	viability after 9 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-1.2515018778845548	[633]	[78,88]	-7	hSpCas9	negative selection	1128244
57257103	57257126	17	+	26627737	RPE1	viability after 9 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-1.2391086329107686	[520]	[86,45]	-7	hSpCas9	negative selection	1128245
57262171	57262194	17	+	26627737	RPE1	viability after 9 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.6086918424989172	[682]	[127,155]	-4	hSpCas9	negative selection	1128246
57616053	57616076	17	+	26627737	RPE1	viability after 9 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.011036604539892525	[1005]	[312,322]	0	hSpCas9	negative selection	1128248
57627240	57627263	17	+	26627737	RPE1	viability after 9 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.21254345883480474	[2119]	[703,852]	1	hSpCas9	negative selection	1128249
57652106	57652129	17	+	26627737	RPE1	viability after 9 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	0.12953234592121543	[1094]	[381,365]	0	hSpCas9	negative selection	1128250
57256782	57256805	17	+	26627737	RPE1	viability after 12 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-0.20472515920748097	[633]	[191,100]	-1	hSpCas9	negative selection	1210559
57257103	57257126	17	+	26627737	RPE1	viability after 12 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-0.5920871647471575	[520]	[70,115]	-4	hSpCas9	negative selection	1210560
57262171	57262194	17	+	26627737	RPE1	viability after 12 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.2411145233399442	[682]	[129,181]	-2	hSpCas9	negative selection	1210561
57616053	57616076	17	+	26627737	RPE1	viability after 12 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.043150609012739705	[1005]	[187,340]	0	hSpCas9	negative selection	1210563
57627240	57627263	17	+	26627737	RPE1	viability after 12 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.12849083328968103	[2119]	[541,707]	0	hSpCas9	negative selection	1210564
57652106	57652129	17	+	26627737	RPE1	viability after 12 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	0.047594928422593163	[1094]	[339,265]	0	hSpCas9	negative selection	1210565
57256782	57256805	17	+	26627737	RPE1	viability after 15 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-1.08582660686196	[633]	[112,56]	-6	hSpCas9	negative selection	1292874
57257103	57257126	17	+	26627737	RPE1	viability after 15 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-1.635529225250806	[520]	[22,70]	-7	hSpCas9	negative selection	1292875
57262171	57262194	17	+	26627737	RPE1	viability after 15 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.1858230040411266	[682]	[232,206]	1	hSpCas9	negative selection	1292876
57616053	57616076	17	+	26627737	RPE1	viability after 15 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.17380444371104053	[1005]	[207,429]	1	hSpCas9	negative selection	1292878
57627240	57627263	17	+	26627737	RPE1	viability after 15 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.26537092156691044	[2119]	[590,845]	1	hSpCas9	negative selection	1292879
57652106	57652129	17	+	26627737	RPE1	viability after 15 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.15618959216088485	[1094]	[335,221]	-1	hSpCas9	negative selection	1292880
57256782	57256805	17	+	26627737	RPE1	viability after 18 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-1.7414270710999662	[633]	[26,76]	-8	hSpCas9	negative selection	1375189
57257103	57257126	17	+	26627737	RPE1	viability after 18 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-1.5054932325770722	[520]	[20,79]	-7	hSpCas9	negative selection	1375190
57262171	57262194	17	+	26627737	RPE1	viability after 18 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.03399251595194269	[682]	[209,147]	0	hSpCas9	negative selection	1375191
57616053	57616076	17	+	26627737	RPE1	viability after 18 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.5177722448796076	[1005]	[277,506]	3	hSpCas9	negative selection	1375193
57627240	57627263	17	+	26627737	RPE1	viability after 18 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.029726222546277548	[2119]	[584,582]	0	hSpCas9	negative selection	1375194
57652106	57652129	17	+	26627737	RPE1	viability after 18 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.1906874645245198	[1094]	[343,167]	-1	hSpCas9	negative selection	1375195
57256782	57256805	17	+	26627737	HeLa	viability after 8 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-0.3907712830871345	[328]	[63,149,103]	-4	hSpCas9	negative selection	1457504
57257103	57257126	17	+	26627737	HeLa	viability after 8 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	0.23993311029951436	[149]	[154,54,40]	2	hSpCas9	negative selection	1457505
57262171	57262194	17	+	26627737	HeLa	viability after 8 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.7603597874762321	[554]	[162,93,172]	-6	hSpCas9	negative selection	1457506
57616053	57616076	17	+	26627737	HeLa	viability after 8 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.08037896267108435	[563]	[211,411,78]	0	hSpCas9	negative selection	1457508
57627240	57627263	17	+	26627737	HeLa	viability after 8 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.20959513499612425	[1510]	[795,765,728]	2	hSpCas9	negative selection	1457509
57652106	57652129	17	+	26627737	HeLa	viability after 8 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	0.35135165786124045	[441]	[198,297,229]	3	hSpCas9	negative selection	1457510
57256782	57256805	17	+	26627737	HeLa	viability after 12 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-0.0570429865622778	[328]	[126,120,144]	0	hSpCas9	negative selection	1539819
57257103	57257126	17	+	26627737	HeLa	viability after 12 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	0.09239183233975301	[149]	[89,27,84]	0	hSpCas9	negative selection	1539820
57262171	57262194	17	+	26627737	HeLa	viability after 12 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.5016951185843539	[554]	[133,172,176]	-4	hSpCas9	negative selection	1539821
57616053	57616076	17	+	26627737	HeLa	viability after 12 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.5482110252754772	[563]	[113,110,256]	-5	hSpCas9	negative selection	1539823
57627240	57627263	17	+	26627737	HeLa	viability after 12 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.4989188373071882	[1510]	[1015,770,875]	4	hSpCas9	negative selection	1539824
57652106	57652129	17	+	26627737	HeLa	viability after 12 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	0.5176549097174119	[441]	[147,272,358]	4	hSpCas9	negative selection	1539825
57256782	57256805	17	+	26627737	HeLa	viability after 15 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	0.7786003682991492	[328]	[391,91,200]	6	hSpCas9	negative selection	1622134
57257103	57257126	17	+	26627737	HeLa	viability after 15 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-0.05929296398168149	[149]	[82,39,51]	0	hSpCas9	negative selection	1622135
57262171	57262194	17	+	26627737	HeLa	viability after 15 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-1.3053081810938623	[554]	[104,102,63]	-8	hSpCas9	negative selection	1622136
57616053	57616076	17	+	26627737	HeLa	viability after 15 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-1.2113346942978738	[563]	[133,27,137]	-8	hSpCas9	negative selection	1622138
57627240	57627263	17	+	26627737	HeLa	viability after 15 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.1750593385446093	[1510]	[634,648,808]	1	hSpCas9	negative selection	1622139
57652106	57652129	17	+	26627737	HeLa	viability after 15 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.7187401515240373	[441]	[61,43,231]	-6	hSpCas9	negative selection	1622140
57256782	57256805	17	+	26627737	HeLa	viability after 18 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	0.8615141592361252	[328]	[287,77,200]	6	hSpCas9	negative selection	1704449
57257103	57257126	17	+	26627737	HeLa	viability after 18 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-0.09500348630075872	[149]	[52,32,51]	-1	hSpCas9	negative selection	1704450
57262171	57262194	17	+	26627737	HeLa	viability after 18 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-1.3305214338086733	[554]	[65,86,63]	-8	hSpCas9	negative selection	1704451
57616053	57616076	17	+	26627737	HeLa	viability after 18 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-1.2132616195323358	[563]	[88,23,137]	-8	hSpCas9	negative selection	1704453
57627240	57627263	17	+	26627737	HeLa	viability after 18 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.17145010669257532	[1510]	[426,531,808]	1	hSpCas9	negative selection	1704454
57652106	57652129	17	+	26627737	HeLa	viability after 18 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.6848604632833251	[441]	[42,40,231]	-6	hSpCas9	negative selection	1704455
57256782	57256805	17	+	26627737	HCT116	viability after 6 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	1.6290217060537928	[106]	[13,72]	8	hSpCas9	negative selection	1786764
57257103	57257126	17	+	26627737	HCT116	viability after 6 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	2.591275957369966	[145]	[98,159]	9	hSpCas9	negative selection	1786765
57262171	57262194	17	+	26627737	HCT116	viability after 6 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.7646318029642482	[785]	[236,194]	4	hSpCas9	negative selection	1786766
57616053	57616076	17	+	26627737	HCT116	viability after 6 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.8414446107368729	[505]	[128,149]	4	hSpCas9	negative selection	1786768
57627240	57627263	17	+	26627737	HCT116	viability after 6 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	-0.011793822828895628	[1489]	[377,151]	0	hSpCas9	negative selection	1786769
57652106	57652129	17	+	26627737	HCT116	viability after 6 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.4621495158330089	[1002]	[292,15]	-3	hSpCas9	negative selection	1786770
57256782	57256805	17	+	26627737	HCT116	viability after 8 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	0.09258627056544363	[247]	[172,149,114]	1	hSpCas9	negative selection	1869079
57257103	57257126	17	+	26627737	HCT116	viability after 8 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	0.4801279211765753	[124]	[130,73,83]	5	hSpCas9	negative selection	1869080
57262171	57262194	17	+	26627737	HCT116	viability after 8 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.4962669230447614	[378]	[196,96,150]	-5	hSpCas9	negative selection	1869081
57616053	57616076	17	+	26627737	HCT116	viability after 8 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.11646122502952808	[288]	[203,185,128]	1	hSpCas9	negative selection	1869083
57627240	57627263	17	+	26627737	HCT116	viability after 8 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.7245888275893637	[807]	[706,712,785]	7	hSpCas9	negative selection	1869084
57652106	57652129	17	+	26627737	HCT116	viability after 8 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.17262410262590522	[530]	[258,277,241]	-2	hSpCas9	negative selection	1869085
57256782	57256805	17	+	26627737	HCT116	viability after 9 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	1.9049898113534685	[106]	[168,57]	9	hSpCas9	negative selection	1951394
57257103	57257126	17	+	26627737	HCT116	viability after 9 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-0.10054015477029754	[145]	[51,23]	0	hSpCas9	negative selection	1951395
57262171	57262194	17	+	26627737	HCT116	viability after 9 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.5188847769947172	[785]	[517,128]	4	hSpCas9	negative selection	1951396
57616053	57616076	17	+	26627737	HCT116	viability after 9 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.5624691768394482	[505]	[203,195]	4	hSpCas9	negative selection	1951398
57627240	57627263	17	+	26627737	HCT116	viability after 9 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.26524935727364807	[1489]	[385,550]	2	hSpCas9	negative selection	1951399
57652106	57652129	17	+	26627737	HCT116	viability after 9 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	0.11524112228052352	[1002]	[231,335]	0	hSpCas9	negative selection	1951400
57256782	57256805	17	+	26627737	HCT116	viability after 12 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	1.170154449837889	[247]	[624,97,122]	8	hSpCas9	negative selection	2033709
57257103	57257126	17	+	26627737	HCT116	viability after 12 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	0.7787233011772334	[124]	[141,90,101]	7	hSpCas9	negative selection	2033710
57262171	57262194	17	+	26627737	HCT116	viability after 12 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.1864029221400356	[378]	[121,184,222]	-2	hSpCas9	negative selection	2033711
57616053	57616076	17	+	26627737	HCT116	viability after 12 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.32500743795133424	[288]	[204,129,232]	3	hSpCas9	negative selection	2033713
57627240	57627263	17	+	26627737	HCT116	viability after 12 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.8906318936447202	[807]	[795,787,776]	7	hSpCas9	negative selection	2033714
57652106	57652129	17	+	26627737	HCT116	viability after 12 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.3886570784025133	[530]	[158,327,159]	-4	hSpCas9	negative selection	2033715
57256782	57256805	17	+	26627737	HCT116	viability after 15 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-0.755665031048852	[247]	[85,143,23]	-6	hSpCas9	negative selection	2116024
57257103	57257126	17	+	26627737	HCT116	viability after 15 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	0.5514247454674714	[124]	[95,71,145]	5	hSpCas9	negative selection	2116025
57262171	57262194	17	+	26627737	HCT116	viability after 15 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.20134307319361305	[378]	[257,105,211]	-2	hSpCas9	negative selection	2116026
57616053	57616076	17	+	26627737	HCT116	viability after 15 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.16888062648618862	[288]	[282,144,143]	1	hSpCas9	negative selection	2116028
57627240	57627263	17	+	26627737	HCT116	viability after 15 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.8837404151511097	[807]	[1042,828,720]	7	hSpCas9	negative selection	2116029
57652106	57652129	17	+	26627737	HCT116	viability after 15 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.42919671852450275	[530]	[252,230,198]	-4	hSpCas9	negative selection	2116030
57256782	57256805	17	+	26627737	HCT116	viability after 18 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	0.4408359440787729	[247]	[227,137,121]	4	hSpCas9	negative selection	2198339
57257103	57257126	17	+	26627737	HCT116	viability after 18 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	0.48216507916948725	[124]	[78,62,113]	4	hSpCas9	negative selection	2198340
57262171	57262194	17	+	26627737	HCT116	viability after 18 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.2965458420215136	[378]	[120,96,236]	-3	hSpCas9	negative selection	2198341
57616053	57616076	17	+	26627737	HCT116	viability after 18 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.2830394817035389	[288]	[178,114,221]	2	hSpCas9	negative selection	2198343
57627240	57627263	17	+	26627737	HCT116	viability after 18 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	1.0013698287298178	[807]	[693,586,1091]	7	hSpCas9	negative selection	2198344
57652106	57652129	17	+	26627737	HCT116	viability after 18 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.20810787064032965	[530]	[215,204,247]	-2	hSpCas9	negative selection	2198345
57584849	57584872	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCGCTCTGTCACCCAGGCTAG	MSI2	ENSG00000153944	-1.0560306979191085	[78,130]	[14,5]	-6	dCas9-VP64	positive selection	2386536
57317548	57317571	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCCAGGCTGGAATGCAGTAG	MSI2	ENSG00000153944	-0.2783317302750946	[134,222]	[33,30]	-1	dCas9-VP64	positive selection	2393433
57558815	57558838	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTTGGGAGGCCAAGGCGGGCAG	MSI2	ENSG00000153944	0.09588317305989913	[114,12]	[10,18]	0	dCas9-VP64	positive selection	2411112
57618590	57618613	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGATCGCGCCACGGCACTCCAG	MSI2	ENSG00000153944	-1.466474382562567	[427,83]	[22,15]	-8	dCas9-VP64	positive selection	2417194
57674985	57675008	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGCCCGGAGGCTTCCCGGGGG	MSI2	ENSG00000153944	2.0012546669376334	[0,1]	[0,0]	7	dCas9-VP64	positive selection	2428163
57411213	57411236	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGTTTGAGACCAGCCTCGG	MSI2	ENSG00000153944	-1.6026008362934678	[306,558]	[26,34]	-8	dCas9-VP64	positive selection	2428503
57477182	57477205	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTGTGTGTCGG	MSI2	ENSG00000153944	4.847110262494055	[32,12]	[264,23]	9	dCas9-VP64	positive selection	2428780
57450424	57450447	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGGCCACAG	MSI2	ENSG00000153944	-3.2327828351083694	[281,50]	[1,4]	-9	dCas9-VP64	positive selection	2431301
57378154	57378177	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCATTGCACTCCAGCCCGG	MSI2	ENSG00000153944	3.359380449218091	[189,5]	[417,3]	8	dCas9-VP64	positive selection	2446626
57321995	57322018	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACTAGCCTGGCCAACATGG	MSI2	ENSG00000153944	0.3601150748164519	[269,268]	[95,53]	1	dCas9-VP64	positive selection	2458967
57256449	57256472	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAGGAGGAGATGGGGGTGGGG	MSI2	ENSG00000153944	1.5210967937787219	[12,29]	[11,15]	5	dCas9-VP64	positive selection	2464788
57256387	57256410	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAACGTCGTGTAACCAATGCCGG	MSI2	ENSG00000153944	1.7365297040796945	[82,75]	[91,22]	6	dCas9-VP64	positive selection	2464789
57256426	57256449	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCGCCGGGGAGGAGGGGGAGG	MSI2	ENSG00000153944	1.9516643608910305	[0,0]	[0,0]	7	dCas9-VP64	positive selection	2464790
57256864	57256887	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGACGGCGGTGCGCGGAGCCGGG	MSI2	ENSG00000153944	-1.4989333614700096	[20,35]	[0,2]	-8	dCas9-VP64	positive selection	2469268
57256920	57256943	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGTGTGTAACTTCCACGGGGGGG	MSI2	ENSG00000153944	1.735760301854369	[1,0]	[0,0]	6	dCas9-VP64	positive selection	2469269
57256843	57256866	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCGCTCTCCTTGCAGCGGCGGGG	MSI2	ENSG00000153944	-0.6214861824011809	[135,134]	[19,17]	-3	dCas9-VP64	positive selection	2469270
57584849	57584872	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCGCTCTGTCACCCAGGCTAG	MSI2	ENSG00000153944	0.7674335835704862	[415,371]	[130,301]	5	dCas9-VP64	positive selection	2481791
57317548	57317571	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCCAGGCTGGAATGCAGTAG	MSI2	ENSG00000153944	4.153514066093628	[144,313]	[24,2552]	9	dCas9-VP64	positive selection	2488688
57558815	57558838	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTTGGGAGGCCAAGGCGGGCAG	MSI2	ENSG00000153944	3.077269363618506	[19,18]	[13,93]	9	dCas9-VP64	positive selection	2506367
57618590	57618613	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGATCGCGCCACGGCACTCCAG	MSI2	ENSG00000153944	-0.11597523021325501	[256,83]	[82,21]	-1	dCas9-VP64	positive selection	2512449
57674985	57675008	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGCCCGGAGGCTTCCCGGGGG	MSI2	ENSG00000153944	-0.5024554397006883	[72,100]	[19,18]	-5	dCas9-VP64	positive selection	2523418
57411213	57411236	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGTTTGAGACCAGCCTCGG	MSI2	ENSG00000153944	0.9241793657004961	[25,55]	[22,26]	6	dCas9-VP64	positive selection	2523758
57477182	57477205	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTGTGTGTCGG	MSI2	ENSG00000153944	0.8889753160498469	[90,141]	[86,53]	6	dCas9-VP64	positive selection	2524035
57450424	57450447	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGGCCACAG	MSI2	ENSG00000153944	0.5850522226976638	[88,64]	[38,35]	4	dCas9-VP64	positive selection	2526556
57378154	57378177	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCATTGCACTCCAGCCCGG	MSI2	ENSG00000153944	0.626840615877442	[158,168]	[52,109]	4	dCas9-VP64	positive selection	2541881
57321995	57322018	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACTAGCCTGGCCAACATGG	MSI2	ENSG00000153944	-0.8374586120276372	[108,300]	[27,44]	-7	dCas9-VP64	positive selection	2554222
57256449	57256472	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAGGAGGAGATGGGGGTGGGG	MSI2	ENSG00000153944	1.5248110650842919	[161,79]	[189,43]	8	dCas9-VP64	positive selection	2560043
57256387	57256410	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAACGTCGTGTAACCAATGCCGG	MSI2	ENSG00000153944	0.4462422458147667	[88,72]	[41,29]	3	dCas9-VP64	positive selection	2560044
57256426	57256449	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCGCCGGGGAGGAGGGGGAGG	MSI2	ENSG00000153944	1.4398846966535364	[37,27]	[57,1]	7	dCas9-VP64	positive selection	2560045
57256864	57256887	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGACGGCGGTGCGCGGAGCCGGG	MSI2	ENSG00000153944	-0.2622022756051168	[13,47]	[6,7]	-2	dCas9-VP64	positive selection	2564523
57256920	57256943	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGTGTGTAACTTCCACGGGGGGG	MSI2	ENSG00000153944	0.3659667006776459	[34,6]	[16,0]	3	dCas9-VP64	positive selection	2564524
57256843	57256866	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCGCTCTCCTTGCAGCGGCGGGG	MSI2	ENSG00000153944	0.10268645350465533	[155,291]	[88,67]	0	dCas9-VP64	positive selection	2564525
57257045	57257068	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAAAATGGCCGATCTGACATCGG	MSI2	ENSG00000153944	-0.3244224938865809	[4,4]	[4,1]	-4	hSpCas9	positive selection	3003507
57258334	57258357	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.01708464772942933	[4,3]	[4,2]	0	hSpCas9	positive selection	3003508
57258302	57258325	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAGTGTAGATAAAGTATTAGG	MSI2	ENSG00000153944	-0.1895230785321304	[4,4]	[4,1]	-3	hSpCas9	positive selection	3003509
57401415	57401438	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.3945439998507022	[4,4]	[4,5]	7	hSpCas9	positive selection	3003510
57257045	57257068	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAAAATGGCCGATCTGACATCGG	MSI2	ENSG00000153944	0.15007515549994377	[4,4]	[3,3]	2	hSpCas9	positive selection	3071365
57258334	57258357	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.5598944057311916	[4,4]	[3,0]	-7	hSpCas9	positive selection	3071366
57258302	57258325	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAGTGTAGATAAAGTATTAGG	MSI2	ENSG00000153944	0.21820733069722908	[4,4]	[3,3]	4	hSpCas9	positive selection	3071367
57401415	57401438	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.46098353793113517	[4,4]	[4,4]	7	hSpCas9	positive selection	3071368
57257526	57257549		+	24336571	A375	resistance to PLX after 7 days	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.42261971624305916	[22,25]	[16,18]	-9	hSpCas9	positive selection	3128659
57258333	57258356		-	24336571	A375	resistance to PLX after 7 days	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.1690552603144403	[10,11]	[11,12]	5	hSpCas9	positive selection	3128660
57257526	57257549		+	24336571	A375	resistance to PLX after 14 days	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.4701019279494494	[25,24]	[6,8]	-5	hSpCas9	positive selection	3186452
57258333	57258356		-	24336571	A375	resistance to PLX after 14 days	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.5460679526435179	[13,11]	[7,9]	5	hSpCas9	positive selection	3186453
57257526	57257549		+	24336571	A375	viability after 7 days	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.3371887571301255	[31]	[22,25]	-5	hSpCas9	negative selection	3244245
57258333	57258356		-	24336571	A375	viability after 7 days	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.3850714167226603	[15]	[10,11]	-5	hSpCas9	negative selection	3244246
57257526	57257549		+	24336571	A375	viability after 14 days	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.23571792393802737	[31]	[25,24]	-3	hSpCas9	negative selection	3302038
57258333	57258356		-	24336571	A375	viability after 14 days	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.13451730183249994	[15]	[13,11]	-1	hSpCas9	negative selection	3302039
57257529	57257552	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	4.087401210003523	[8,8]	[0,0]	9	hSpCas9	positive selection	3380173
57258333	57258356	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-1.238528815441336	[360,360]	[0,0]	-7	hSpCas9	positive selection	3380174
57258333	57258356	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.10757909194115295	[141,141]	[0,0]	0	hSpCas9	positive selection	3380175
57257044	57257067	17	+	26780180	HT29	viability (Avana library 4 designs)	CAAAATGGCCGATCTGACATCGG	MSI2	ENSG00000153944	0.878673725455598	[]	[]	3	hSpCas9	negative selection	3441279
57258333	57258356	17	+	26780180	HT29	viability (Avana library 4 designs)	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.286885594864663	[]	[]	-4	hSpCas9	negative selection	3441280
57258301	57258324	17	+	26780180	HT29	viability (Avana library 4 designs)	GCAAGTGTAGATAAAGTATTAGG	MSI2	ENSG00000153944	1.09242079000536	[]	[]	4	hSpCas9	negative selection	3441281
57401414	57401437	17	+	26780180	HT29	viability (Avana library 4 designs)	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	1.15399371001465	[]	[]	4	hSpCas9	negative selection	3441282
57401414	57401437	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-1.26371751819636	[]	[]	-1	hSpCas9	negative selection	3531901
57258333	57258356	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-6.11854579194428	[]	[]	-6	hSpCas9	negative selection	3531902
57258301	57258324	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAGTGTAGATAAAGTATTAGG	MSI2	ENSG00000153944	-7.34813206873047	[]	[]	-6	hSpCas9	negative selection	3531903
57257044	57257067	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAAAATGGCCGATCTGACATCGG	MSI2	ENSG00000153944	-0.20182199427254	[]	[]	0	hSpCas9	negative selection	3531904
57257529	57257552	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-6.27937724407882	[]	[]	-6	hSpCas9	negative selection	3531905
57258337	57258360	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTTAGATTCCAAGACGGTAGG	MSI2	ENSG00000153944	2.11505451563648	[]	[]	3	hSpCas9	negative selection	3531906
57401414	57401437	17	+	26780180	A375	viability (Avana lentiGuide)	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	2.40469573149567	[]	[]	2	hSpCas9	negative selection	3640560
57258333	57258356	17	+	26780180	A375	viability (Avana lentiGuide)	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-2.17197043204277	[]	[]	-4	hSpCas9	negative selection	3640561
57258301	57258324	17	+	26780180	A375	viability (Avana lentiGuide)	GCAAGTGTAGATAAAGTATTAGG	MSI2	ENSG00000153944	5.76295941686892	[]	[]	5	hSpCas9	negative selection	3640562
57257044	57257067	17	+	26780180	A375	viability (Avana lentiGuide)	CAAAATGGCCGATCTGACATCGG	MSI2	ENSG00000153944	3.08755646433793	[]	[]	3	hSpCas9	negative selection	3640563
57257529	57257552	17	-	26780180	A375	viability (Avana lentiGuide)	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	3.4754661119439	[]	[]	3	hSpCas9	negative selection	3640564
57258337	57258360	17	+	26780180	A375	viability (Avana lentiGuide)	GAGTTAGATTCCAAGACGGTAGG	MSI2	ENSG00000153944	4.37997513559114	[]	[]	4	hSpCas9	negative selection	3640565
57401414	57401437	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.08176060563933629	[6]	[5,6]	-1	hSpCas9	positive selection	3749219
57258333	57258356	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.26436675706420315	[5]	[4,4]	-4	hSpCas9	positive selection	3749220
57258301	57258324	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAGTGTAGATAAAGTATTAGG	MSI2	ENSG00000153944	-0.4019653330120122	[7]	[5,5]	-5	hSpCas9	positive selection	3749221
57257044	57257067	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAAAATGGCCGATCTGACATCGG	MSI2	ENSG00000153944	-0.040790661539530024	[4]	[4,4]	0	hSpCas9	positive selection	3749222
57257529	57257552	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.28407906045108994	[4]	[4,3]	-4	hSpCas9	positive selection	3749223
57258337	57258360	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTTAGATTCCAAGACGGTAGG	MSI2	ENSG00000153944	0.04021651993064329	[4]	[4,4]	1	hSpCas9	positive selection	3749224
57401414	57401437	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.17587280692195129	[6]	[6,6]	4	hSpCas9	positive selection	3857826
57258333	57258356	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.04920038515917098	[5]	[5,4]	1	hSpCas9	positive selection	3857827
57258301	57258324	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAGTGTAGATAAAGTATTAGG	MSI2	ENSG00000153944	0.012300648795610047	[6]	[5,4]	0	hSpCas9	positive selection	3857828
57257044	57257067	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAAAATGGCCGATCTGACATCGG	MSI2	ENSG00000153944	0.08318097255555681	[6]	[6,4]	1	hSpCas9	positive selection	3857829
57257529	57257552	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.5789423120628349	[5]	[3,1]	-6	hSpCas9	positive selection	3857830
57258337	57258360	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTTAGATTCCAAGACGGTAGG	MSI2	ENSG00000153944	-0.6417815040008481	[4]	[0,3]	-7	hSpCas9	positive selection	3857831
57262172	57262195	17	-	26780180	A375	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	1.33029354194985	[]	[]	7	hSpCas9	negative selection	3969220
57257526	57257549	17	+	26780180	A375	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	2.29158981776052	[]	[]	9	hSpCas9	negative selection	3969221
57258333	57258356	17	+	26780180	A375	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.865585062373147	[]	[]	3	hSpCas9	negative selection	3969222
57258333	57258356	17	-	26780180	A375	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	1.38999799665937	[]	[]	7	hSpCas9	negative selection	3969223
57262171	57262194	17	+	26780180	A375	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	1.35931210966462	[]	[]	7	hSpCas9	negative selection	3969224
57257529	57257552	17	-	26780180	A375	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	0.517205126460073	[]	[]	1	hSpCas9	negative selection	3969225
57262172	57262195	17	-	26780180	HT29	viability (GeCKOv2 library)	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	2.00980920031553	[]	[]	9	hSpCas9	negative selection	4077186
57257526	57257549	17	+	26780180	HT29	viability (GeCKOv2 library)	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	2.53193443894048	[]	[]	9	hSpCas9	negative selection	4077187
57258333	57258356	17	+	26780180	HT29	viability (GeCKOv2 library)	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.602916043197104	[]	[]	2	hSpCas9	negative selection	4077188
57258333	57258356	17	-	26780180	HT29	viability (GeCKOv2 library)	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	1.04248640942636	[]	[]	5	hSpCas9	negative selection	4077189
57262171	57262194	17	+	26780180	HT29	viability (GeCKOv2 library)	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	1.17003187989191	[]	[]	5	hSpCas9	negative selection	4077190
57257529	57257552	17	-	26780180	HT29	viability (GeCKOv2 library)	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	0.670414232699098	[]	[]	2	hSpCas9	negative selection	4077191
57257526	57257549	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.21642687016072415	[4]	[1,2]	-5	hSpCas9	positive selection	4153136
57258333	57258356	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.0336160251828181	[3]	[1,3]	-1	hSpCas9	positive selection	4153137
57257526	57257549	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.6844189077351707	[4]	[3,1,0,4]	4	hSpCas9	positive selection	4217158
57258333	57258356	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.17282896555465915	[3]	[1,1,4,0]	1	hSpCas9	positive selection	4217159
57257526	57257549	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.28935237992408025	[4]	[2,2]	-5	hSpCas9	positive selection	4283865
57262172	57262195	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	-0.5602465169914288	[2]	[1,0]	-8	hSpCas9	positive selection	4283866
57262171	57262194	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.007985354413434342	[2]	[2,0]	0	hSpCas9	positive selection	4283867
57257529	57257552	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.02310311138251442	[0]	[0,0]	0	hSpCas9	positive selection	4348123
57258333	57258356	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.153630195815964	[3]	[3,2]	3	hSpCas9	positive selection	4348124
57258333	57258356	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.19128569119119074	[2]	[1,1]	-4	hSpCas9	positive selection	4348125
57257527	57257549	17	+	27760321	OCIAML3	viability	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.1541402051252294	[707,633]	[396,825]	1	hSpCas9	negative selection	4419765
57258333	57258355	17	-	27760321	OCIAML3	viability	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.25382248727164036	[222,207]	[97,197]	-3	hSpCas9	negative selection	4419766
57262147	57262169	17	-	27760321	OCIAML3	viability	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	0.5272454089752019	[599,492]	[586,646]	6	hSpCas9	negative selection	4419767
57262172	57262194	17	-	27760321	OCIAML3	viability	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.06610862184177968	[1027,920]	[680,947]	0	hSpCas9	negative selection	4419768
57401415	57401437	17	+	27760321	OCIAML3	viability	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-1.2817268666273094	[214,189]	[51,81]	-8	hSpCas9	negative selection	4419769
57257527	57257549	17	+	27760321	OCIAML2	viability	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.24161302817088437	[707,633]	[539,773]	3	hSpCas9	negative selection	4503228
57258333	57258355	17	-	27760321	OCIAML2	viability	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.3483799364394501	[222,207]	[215,229]	5	hSpCas9	negative selection	4503229
57262147	57262169	17	-	27760321	OCIAML2	viability	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	0.4912544752209864	[599,492]	[463,821]	6	hSpCas9	negative selection	4503230
57262172	57262194	17	-	27760321	OCIAML2	viability	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.10939153906054022	[1027,920]	[791,924]	1	hSpCas9	negative selection	4503231
57401415	57401437	17	+	27760321	OCIAML2	viability	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.13961424740409245	[214,189]	[125,177]	-2	hSpCas9	negative selection	4503232
57257527	57257549	17	+	27760321	MV411	viability	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.8065168139866485	[707,633]	[321,148]	-5	hSpCas9	negative selection	4586691
57258333	57258355	17	-	27760321	MV411	viability	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.22310539171857802	[222,207]	[0,413]	1	hSpCas9	negative selection	4586692
57262147	57262169	17	-	27760321	MV411	viability	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	0.5990601888395714	[599,492]	[627,416]	4	hSpCas9	negative selection	4586693
57262172	57262194	17	-	27760321	MV411	viability	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	-0.08900299334000672	[1027,920]	[435,855]	0	hSpCas9	negative selection	4586694
57401415	57401437	17	+	27760321	MV411	viability	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-1.7099895724907488	[214,189]	[7,89]	-8	hSpCas9	negative selection	4586695
57257527	57257549	17	+	27760321	HL60	viability	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.1578486767041426	[707,633]	[364,623]	-2	hSpCas9	negative selection	4670154
57258333	57258355	17	-	27760321	HL60	viability	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.5201343947859784	[222,207]	[237,267]	6	hSpCas9	negative selection	4670155
57262147	57262169	17	-	27760321	HL60	viability	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	-0.015423916484203104	[599,492]	[408,471]	0	hSpCas9	negative selection	4670156
57262172	57262194	17	-	27760321	HL60	viability	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.5052108138251379	[1027,920]	[994,1269]	6	hSpCas9	negative selection	4670157
57401415	57401437	17	+	27760321	HL60	viability	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.7953171320220331	[214,189]	[99,89]	-7	hSpCas9	negative selection	4670158
57257527	57257549	17	+	27760321	HT1080	viability	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-1.7755232585987688	[633,494]	[37,95]	-6	hSpCas9	negative selection	4753617
57258333	57258355	17	-	27760321	HT1080	viability	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.9558001228409159	[207,162]	[71,0]	-4	hSpCas9	negative selection	4753618
57262147	57262169	17	-	27760321	HT1080	viability	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	-1.4678567636010893	[492,384]	[67,57]	-5	hSpCas9	negative selection	4753619
57262172	57262194	17	-	27760321	HT1080	viability	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	-1.8730759365393488	[920,718]	[113,61]	-6	hSpCas9	negative selection	4753620
57401415	57401437	17	+	27760321	HT1080	viability	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-3.9547073263676222	[189,147]	[0,7]	-8	hSpCas9	negative selection	4753621
57257527	57257549	17	+	27760321	HT29	viability after 7 days	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.017024879381654867	[633,494]	[1015,605,575]	0	hSpCas9	negative selection	4837080
57258333	57258355	17	-	27760321	HT29	viability after 7 days	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.2595029411071429	[207,162]	[417,133,321]	4	hSpCas9	negative selection	4837081
57262147	57262169	17	-	27760321	HT29	viability after 7 days	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	0.47645684887426765	[492,384]	[817,739,800]	7	hSpCas9	negative selection	4837082
57262172	57262194	17	-	27760321	HT29	viability after 7 days	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.050568521179866766	[920,718]	[1113,743,1408]	0	hSpCas9	negative selection	4837083
57401415	57401437	17	+	27760321	HT29	viability after 7 days	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-1.5064870427204071	[189,147]	[59,123,43]	-9	hSpCas9	negative selection	4837084
57257527	57257549	17	+	27760321	HT29	viability after 25 days	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.2400838257796395	[633,494]	[654,679,978]	2	hSpCas9	negative selection	4920543
57258333	57258355	17	-	27760321	HT29	viability after 25 days	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.163699212268828	[207,162]	[285,255,158]	1	hSpCas9	negative selection	4920544
57262147	57262169	17	-	27760321	HT29	viability after 25 days	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	0.8585816683996528	[492,384]	[1003,884,823]	8	hSpCas9	negative selection	4920545
57262172	57262194	17	-	27760321	HT29	viability after 25 days	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	-0.011094145297273927	[920,718]	[881,793,1136]	0	hSpCas9	negative selection	4920546
57401415	57401437	17	+	27760321	HT29	viability after 25 days	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-1.1843014574298074	[189,147]	[96,37,122]	-7	hSpCas9	negative selection	4920547
57257527	57257549	17	+	27760321	HT29	viability after 22 days	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.03767610811417588	[633,494]	[847,567,587]	0	hSpCas9	negative selection	5004006
57258333	57258355	17	-	27760321	HT29	viability after 22 days	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.10723262988456428	[207,162]	[158,290,147]	-1	hSpCas9	negative selection	5004007
57262147	57262169	17	-	27760321	HT29	viability after 22 days	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	0.5248034417442463	[492,384]	[1009,650,519]	6	hSpCas9	negative selection	5004008
57262172	57262194	17	-	27760321	HT29	viability after 22 days	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.178732281334415	[920,718]	[1108,1139,967]	1	hSpCas9	negative selection	5004009
57401415	57401437	17	+	27760321	HT29	viability after 22 days	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.05739033813729688	[189,147]	[245,86,228]	0	hSpCas9	negative selection	5004010
57257527	57257549	17	+	27760321	HT29	viability after 19 days	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.0813531229583605	[633,494]	[704,841,304]	0	hSpCas9	negative selection	5087469
57258333	57258355	17	-	27760321	HT29	viability after 19 days	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.14747247024130994	[207,162]	[236,220,123]	-1	hSpCas9	negative selection	5087470
57262147	57262169	17	-	27760321	HT29	viability after 19 days	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	0.7278485476297647	[492,384]	[868,1118,521]	7	hSpCas9	negative selection	5087471
57262172	57262194	17	-	27760321	HT29	viability after 19 days	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.2753353277810089	[920,718]	[940,1655,799]	2	hSpCas9	negative selection	5087472
57401415	57401437	17	+	27760321	HT29	viability after 19 days	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.4838907288965715	[189,147]	[75,33,291]	-4	hSpCas9	negative selection	5087473
57257527	57257549	17	+	27760321	HT29	viability after 16 days	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.18616577621046737	[633,494]	[754,834,565]	2	hSpCas9	negative selection	5170932
57258333	57258355	17	-	27760321	HT29	viability after 16 days	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.09754949676217928	[207,162]	[124,174,275]	-1	hSpCas9	negative selection	5170933
57262147	57262169	17	-	27760321	HT29	viability after 16 days	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	1.0439771040297798	[492,384]	[1363,716,997]	9	hSpCas9	negative selection	5170934
57262172	57262194	17	-	27760321	HT29	viability after 16 days	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.057670066538816345	[920,718]	[770,1070,1001]	0	hSpCas9	negative selection	5170935
57401415	57401437	17	+	27760321	HT29	viability after 16 days	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.5186019750865585	[189,147]	[275,35,99]	-5	hSpCas9	negative selection	5170936
57257527	57257549	17	+	27760321	HT29	viability after 13 days	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.3412972360088758	[633,494]	[563,544,445]	-4	hSpCas9	negative selection	5254395
57258333	57258355	17	-	27760321	HT29	viability after 13 days	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.13621264729988636	[207,162]	[182,232,172]	-2	hSpCas9	negative selection	5254396
57262147	57262169	17	-	27760321	HT29	viability after 13 days	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	0.5952547538183878	[492,384]	[664,679,951]	7	hSpCas9	negative selection	5254397
57262172	57262194	17	-	27760321	HT29	viability after 13 days	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.05835417058974457	[920,718]	[1105,682,1170]	0	hSpCas9	negative selection	5254398
57401415	57401437	17	+	27760321	HT29	viability after 13 days	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.8835944394965816	[189,147]	[131,136,52]	-7	hSpCas9	negative selection	5254399
57257527	57257549	17	+	27760321	HT29	viability after 10 days	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.14897826065600583	[633,494]	[964,691,686]	2	hSpCas9	negative selection	5337858
57258333	57258355	17	-	27760321	HT29	viability after 10 days	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.08669321770454108	[207,162]	[172,418,152]	1	hSpCas9	negative selection	5337859
57262147	57262169	17	-	27760321	HT29	viability after 10 days	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	0.496342506860183	[492,384]	[726,642,941]	6	hSpCas9	negative selection	5337860
57262172	57262194	17	-	27760321	HT29	viability after 10 days	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.31152543445331604	[920,718]	[1211,1164,1427]	4	hSpCas9	negative selection	5337861
57401415	57401437	17	+	27760321	HT29	viability after 10 days	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.47037432015205694	[189,147]	[39,125,286]	-5	hSpCas9	negative selection	5337862
57257527	57257549	17	+	27760321	MOLM13	viability	TCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.06058713210203692	[707,633]	[112,574]	0	hSpCas9	negative selection	5421321
57258333	57258355	17	-	27760321	MOLM13	viability	CGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	1.1042866385550765	[222,207]	[99,398]	7	hSpCas9	negative selection	5421322
57262147	57262169	17	-	27760321	MOLM13	viability	TGCAACTTTGGGGTCAATCTGG	MSI2	ENSG00000153944	1.0175900808123939	[599,492]	[610,629]	7	hSpCas9	negative selection	5421323
57262172	57262194	17	-	27760321	MOLM13	viability	CCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	-0.0913862327062529	[1027,920]	[549,485]	0	hSpCas9	negative selection	5421324
57401415	57401437	17	+	27760321	MOLM13	viability	TTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-2.1683318714351056	[214,189]	[53,0]	-8	hSpCas9	negative selection	5421325
57256563	57256586	17	+	27661255	K562	viability	GACGGCTCTCGCCGCTGCCCCGG	MSI2	ENSG00000153944	0.0916991471192441	[1547,1514]	[1477,1155]	3	dCas9-KRAB	negative selection	5494413
57256653	57256676	17	+	27661255	K562	viability	GAGATCTCGGGGCTCGGAGCCGG	MSI2	ENSG00000153944	-0.06548779471618663	[818,978]	[723,649]	-3	dCas9-KRAB	negative selection	5494414
57257526	57257549	17	+	27260156	BXPC3	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.09454188575560996	[1186]	[983,1200,1108,1391]	-2	hSpCas9	negative selection	5556325
57262172	57262195	17	-	27260156	BXPC3	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.12093265171077638	[263]	[163,379,306,365]	2	hSpCas9	negative selection	5556326
57262171	57262194	17	+	27260156	BXPC3	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.163684652460798	[279]	[200,365,434,319]	3	hSpCas9	negative selection	5556327
57257529	57257552	17	-	27260156	BXPC3	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.3049120615546306	[38]	[8,61,8,54]	-6	hSpCas9	negative selection	5620583
57258333	57258356	17	+	27260156	BXPC3	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.017079148469770433	[753]	[764,688,767,911]	0	hSpCas9	negative selection	5620584
57258333	57258356	17	-	27260156	BXPC3	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.027251879557108283	[432]	[402,405,567,478]	0	hSpCas9	negative selection	5620585
57257526	57257549	17	+	27260156	A673	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.10181624763089192	[1186]	[1399,1293,1229,1399]	-3	hSpCas9	negative selection	5677576
57262172	57262195	17	-	27260156	A673	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.2063075576714095	[263]	[342,423,301,390]	5	hSpCas9	negative selection	5677577
57262171	57262194	17	+	27260156	A673	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.10374176590076223	[279]	[431,351,296,372]	2	hSpCas9	negative selection	5677578
57257529	57257552	17	-	27260156	A673	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	0.3660864593134803	[38]	[47,10,100,81]	8	hSpCas9	negative selection	5741834
57258333	57258356	17	+	27260156	A673	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.10908964252055542	[753]	[917,1005,1056,910]	2	hSpCas9	negative selection	5741835
57258333	57258356	17	-	27260156	A673	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.016496364378663878	[432]	[589,503,531,481]	0	hSpCas9	negative selection	5741836
57257526	57257549	17	+	27260156	A375	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.03203607638280137	[1186]	[1619,1257,1450,1325]	0	hSpCas9	negative selection	5798827
57262172	57262195	17	-	27260156	A375	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.1350197207576076	[263]	[306,438,283,336]	2	hSpCas9	negative selection	5798828
57262171	57262194	17	+	27260156	A375	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.32610035290922357	[279]	[258,232,307,240]	-5	hSpCas9	negative selection	5798829
57257529	57257552	17	-	27260156	A375	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-1.1980648741843911	[38]	[0,33,33,12]	-8	hSpCas9	negative selection	5863085
57258333	57258356	17	+	27260156	A375	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.1574062570293444	[753]	[831,936,679,733]	-2	hSpCas9	negative selection	5863086
57258333	57258356	17	-	27260156	A375	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.7709788297805118	[432]	[363,294,324,210]	-7	hSpCas9	negative selection	5863087
57257526	57257549	17	+	27260156	COLO741	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.2507355537652016	[1186]	[1389,1336,1115]	-5	hSpCas9	negative selection	5920078
57262172	57262195	17	-	27260156	COLO741	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.005343480406816314	[263]	[375,302,338]	0	hSpCas9	negative selection	5920079
57262171	57262194	17	+	27260156	COLO741	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.11427478335851515	[279]	[356,394,404]	2	hSpCas9	negative selection	5920080
57257529	57257552	17	-	27260156	COLO741	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.7714989115019151	[38]	[20,38,26]	-9	hSpCas9	negative selection	5984336
57258333	57258356	17	+	27260156	COLO741	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.17942750770406424	[753]	[856,859,834]	-4	hSpCas9	negative selection	5984337
57258333	57258356	17	-	27260156	COLO741	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.5015006747053291	[432]	[316,423,421]	-8	hSpCas9	negative selection	5984338
57257526	57257549	17	+	27260156	CAL120	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.2176778402943247	[1186]	[1252,1365,1189]	-3	hSpCas9	negative selection	6041329
57262172	57262195	17	-	27260156	CAL120	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	-0.07340474608147352	[263]	[236,307,378]	-1	hSpCas9	negative selection	6041330
57262171	57262194	17	+	27260156	CAL120	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.16247371852761028	[279]	[432,341,400]	2	hSpCas9	negative selection	6041331
57257529	57257552	17	-	27260156	CAL120	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.6473431608283899	[38]	[63,7,25]	-7	hSpCas9	negative selection	6105587
57258333	57258356	17	+	27260156	CAL120	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.35344615655885037	[753]	[1163,1311,1115]	5	hSpCas9	negative selection	6105588
57258333	57258356	17	-	27260156	CAL120	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.03569114297248059	[432]	[480,617,471]	0	hSpCas9	negative selection	6105589
57257526	57257549	17	+	27260156	CADOES1	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.25918004880874745	[1186]	[838,833,909,1113]	-4	hSpCas9	negative selection	6162580
57262172	57262195	17	-	27260156	CADOES1	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	-0.05236562538805889	[263]	[263,269,230,179]	-1	hSpCas9	negative selection	6162581
57262171	57262194	17	+	27260156	CADOES1	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.03540925083310564	[279]	[280,271,311,199]	0	hSpCas9	negative selection	6162582
57257529	57257552	17	-	27260156	CADOES1	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-2.1076889897213853	[38]	[12,1,0,17]	-9	hSpCas9	negative selection	6226838
57258333	57258356	17	+	27260156	CADOES1	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.037447955971622426	[753]	[513,799,857,706]	0	hSpCas9	negative selection	6226839
57258333	57258356	17	-	27260156	CADOES1	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.47349778026731626	[432]	[378,257,229,292]	-7	hSpCas9	negative selection	6226840
57257526	57257549	17	+	27260156	EWS502	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.11393397700004915	[1186]	[1336,1118,1419,1590]	2	hSpCas9	negative selection	6283831
57262172	57262195	17	-	27260156	EWS502	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.005813379633246241	[263]	[261,313,275,269]	0	hSpCas9	negative selection	6283832
57262171	57262194	17	+	27260156	EWS502	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.3733799627884515	[279]	[356,343,457,381]	6	hSpCas9	negative selection	6283833
57257529	57257552	17	-	27260156	EWS502	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.7666249648896839	[38]	[16,34,11,33]	-8	hSpCas9	negative selection	6348089
57258333	57258356	17	+	27260156	EWS502	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.11811832989584303	[753]	[898,747,851,972]	2	hSpCas9	negative selection	6348090
57258333	57258356	17	-	27260156	EWS502	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.2585292574448916	[432]	[411,626,518,654]	4	hSpCas9	negative selection	6348091
57257526	57257549	17	+	27260156	EW8	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.06642911116994799	[1186]	[1130,992,897,677]	-1	hSpCas9	negative selection	6405082
57262172	57262195	17	-	27260156	EW8	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.39640507824450893	[263]	[302,201,409,190]	7	hSpCas9	negative selection	6405083
57262171	57262194	17	+	27260156	EW8	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.042399970522253194	[279]	[297,285,141,230]	0	hSpCas9	negative selection	6405084
57257529	57257552	17	-	27260156	EW8	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-1.283087109607262	[38]	[3,4,17,22]	-9	hSpCas9	negative selection	6469340
57258333	57258356	17	+	27260156	EW8	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.0959030188119816	[753]	[684,667,540,409]	-2	hSpCas9	negative selection	6469341
57258333	57258356	17	-	27260156	EW8	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.2985528298045108	[432]	[349,335,279,182]	-5	hSpCas9	negative selection	6469342
57257526	57257549	17	+	27260156	CORL105	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.10292113556113613	[1186]	[1319,1243,1518,1129]	-2	hSpCas9	negative selection	6526333
57262172	57262195	17	-	27260156	CORL105	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.3234223842624656	[263]	[560,248,457,298]	6	hSpCas9	negative selection	6526334
57262171	57262194	17	+	27260156	CORL105	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.09632465014113667	[279]	[264,353,348,429]	1	hSpCas9	negative selection	6526335
57257529	57257552	17	-	27260156	CORL105	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-1.2927307198915416	[38]	[23,10,31,9]	-9	hSpCas9	negative selection	6590591
57258333	57258356	17	+	27260156	CORL105	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.1127096498854635	[753]	[736,1017,1141,940]	2	hSpCas9	negative selection	6590592
57258333	57258356	17	-	27260156	CORL105	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.141384702510727	[432]	[410,449,587,407]	-3	hSpCas9	negative selection	6590593
57257526	57257549	17	+	27260156	HS294T	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.1580659352365561	[1186]	[387,620,388,685]	2	hSpCas9	negative selection	6647584
57262172	57262195	17	-	27260156	HS294T	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.3724433174534124	[263]	[201,91,74,157]	5	hSpCas9	negative selection	6647585
57262171	57262194	17	+	27260156	HS294T	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.42300771988907526	[279]	[49,73,105,98]	-6	hSpCas9	negative selection	6647586
57257529	57257552	17	-	27260156	HS294T	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-2.076324208203485	[38]	[0,1,5,5]	-9	hSpCas9	negative selection	6711842
57258333	57258356	17	+	27260156	HS294T	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.17549580809056453	[753]	[230,199,248,375]	-2	hSpCas9	negative selection	6711843
57258333	57258356	17	-	27260156	HS294T	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.7924073603615758	[432]	[50,125,109,103]	-8	hSpCas9	negative selection	6711844
57257526	57257549	17	+	27260156	HCC44	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.05834700501598311	[1186]	[1471,1269,1839,1108]	0	hSpCas9	negative selection	6768835
57262172	57262195	17	-	27260156	HCC44	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.22025103731140994	[263]	[488,218,416,307]	3	hSpCas9	negative selection	6768836
57262171	57262194	17	+	27260156	HCC44	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.17822468240035283	[279]	[366,372,413,286]	3	hSpCas9	negative selection	6768837
57257529	57257552	17	-	27260156	HCC44	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.9212549445577878	[38]	[2,59,4,14]	-8	hSpCas9	negative selection	6833093
57258333	57258356	17	+	27260156	HCC44	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.11516253314485136	[753]	[818,984,1028,855]	1	hSpCas9	negative selection	6833094
57258333	57258356	17	-	27260156	HCC44	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.2749842548393414	[432]	[625,420,794,585]	4	hSpCas9	negative selection	6833095
57257526	57257549	17	+	27260156	G402	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.41326430853324947	[1186]	[1937,1209,1355,3104]	5	hSpCas9	negative selection	6890086
57262172	57262195	17	-	27260156	G402	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	-0.23649232786592256	[263]	[249,286,341,213]	-3	hSpCas9	negative selection	6890087
57262171	57262194	17	+	27260156	G402	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.7507745482853756	[279]	[871,578,790,120]	8	hSpCas9	negative selection	6890088
57257529	57257552	17	-	27260156	G402	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.9596159789697021	[38]	[8,0,76,7]	-8	hSpCas9	negative selection	6954344
57258333	57258356	17	+	27260156	G402	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.1674678859201998	[753]	[916,1110,802,489]	-2	hSpCas9	negative selection	6954345
57258333	57258356	17	-	27260156	G402	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.5583959038821974	[432]	[345,405,331,350]	-6	hSpCas9	negative selection	6954346
57257526	57257549	17	+	27260156	L33	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.23878226164526128	[1186]	[1012,426,605,1003]	-5	hSpCas9	negative selection	7011337
57262172	57262195	17	-	27260156	L33	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.30488254624914757	[263]	[274,152,213,316]	6	hSpCas9	negative selection	7011338
57262171	57262194	17	+	27260156	L33	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.128481175096247	[279]	[289,94,169,430]	3	hSpCas9	negative selection	7011339
57257529	57257552	17	-	27260156	L33	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-2.2700876573392392	[38]	[4,6,3,3]	-9	hSpCas9	negative selection	7075595
57258333	57258356	17	+	27260156	L33	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.05424414946524536	[753]	[650,372,594,628]	1	hSpCas9	negative selection	7075596
57258333	57258356	17	-	27260156	L33	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.49286486288204934	[432]	[355,107,162,349]	-8	hSpCas9	negative selection	7075597
57257526	57257549	17	+	27260156	K562	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.006343095065709514	[1186]	[1219,1003,936,1041]	0	hSpCas9	negative selection	7132588
57262172	57262195	17	-	27260156	K562	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.9667738992514519	[263]	[459,867,184,350]	9	hSpCas9	negative selection	7132589
57262171	57262194	17	+	27260156	K562	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.672814680155864	[279]	[132,155,270,70]	-7	hSpCas9	negative selection	7132590
57257529	57257552	17	-	27260156	K562	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-2.821467075280662	[38]	[0,14,0,2]	-9	hSpCas9	negative selection	7196846
57258333	57258356	17	+	27260156	K562	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.04260644770074551	[753]	[623,564,483,887]	0	hSpCas9	negative selection	7196847
57258333	57258356	17	-	27260156	K562	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.0656341734112914	[432]	[622,168,453,245]	-1	hSpCas9	negative selection	7196848
57257526	57257549	17	+	27260156	HT29	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.05248885445953144	[1186]	[1701,1494,1607,1219]	1	hSpCas9	negative selection	7253839
57262172	57262195	17	-	27260156	HT29	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.2665881788295926	[263]	[546,368,408,244]	5	hSpCas9	negative selection	7253840
57262171	57262194	17	+	27260156	HT29	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.2512637106917917	[279]	[411,496,383,340]	5	hSpCas9	negative selection	7253841
57257529	57257552	17	-	27260156	HT29	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.8969118990306075	[38]	[8,57,35,2]	-8	hSpCas9	negative selection	7318097
57258333	57258356	17	+	27260156	HT29	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.25936362934912416	[753]	[1281,1087,1152,895]	5	hSpCas9	negative selection	7318098
57258333	57258356	17	-	27260156	HT29	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	0.12840079299451224	[432]	[638,503,523,622]	2	hSpCas9	negative selection	7318099
57257526	57257549	17	+	27260156	MHHES1	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.05553844400647345	[1186]	[1556,1189,1107,1282]	-1	hSpCas9	negative selection	7375090
57262172	57262195	17	-	27260156	MHHES1	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.2870995601868048	[263]	[317,423,619,136]	5	hSpCas9	negative selection	7375091
57262171	57262194	17	+	27260156	MHHES1	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.07494863726873413	[279]	[414,382,299,255]	1	hSpCas9	negative selection	7375092
57257529	57257552	17	-	27260156	MHHES1	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-1.1623341466383632	[38]	[0,28,7,34]	-9	hSpCas9	negative selection	7439348
57258333	57258356	17	+	27260156	MHHES1	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.2738219916577515	[753]	[684,568,966,585]	-5	hSpCas9	negative selection	7439349
57258333	57258356	17	-	27260156	MHHES1	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.15897053774441072	[432]	[469,688,326,309]	-3	hSpCas9	negative selection	7439350
57257526	57257549	17	+	27260156	MEWO	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.09213390722859982	[1186]	[1113,1078,945]	-2	hSpCas9	negative selection	7496341
57262172	57262195	17	-	27260156	MEWO	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.009897103461774082	[263]	[171,279,278]	0	hSpCas9	negative selection	7496342
57262171	57262194	17	+	27260156	MEWO	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.44428687874250816	[279]	[204,181,192]	-7	hSpCas9	negative selection	7496343
57257529	57257552	17	-	27260156	MEWO	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-2.2396475978465196	[38]	[16,1,5]	-9	hSpCas9	negative selection	7560599
57258333	57258356	17	+	27260156	MEWO	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.15163874598411198	[753]	[732,621,568]	-3	hSpCas9	negative selection	7560600
57258333	57258356	17	-	27260156	MEWO	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.14317297888127756	[432]	[438,444,229]	-3	hSpCas9	negative selection	7560601
57257526	57257549	17	+	27260156	LNCAPCLONEFGC	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.12802768435484824	[1186]	[1221,1131,1206,1144]	2	hSpCas9	negative selection	7617592
57262172	57262195	17	-	27260156	LNCAPCLONEFGC	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.7627283030913805	[263]	[419,447,508,257]	9	hSpCas9	negative selection	7617593
57262171	57262194	17	+	27260156	LNCAPCLONEFGC	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.017925768040419454	[279]	[353,132,306,221]	0	hSpCas9	negative selection	7617594
57257529	57257552	17	-	27260156	LNCAPCLONEFGC	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.9727555711256661	[38]	[24,31,4,6]	-8	hSpCas9	negative selection	7681850
57258333	57258356	17	+	27260156	LNCAPCLONEFGC	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.06535498464632727	[753]	[598,583,976,747]	1	hSpCas9	negative selection	7681851
57258333	57258356	17	-	27260156	LNCAPCLONEFGC	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.10604159536620057	[432]	[497,226,323,408]	-2	hSpCas9	negative selection	7681852
57257526	57257549	17	+	27260156	PANC0327	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.12930000909856987	[1186]	[1171,837,883,994]	-2	hSpCas9	negative selection	7738843
57262172	57262195	17	-	27260156	PANC0327	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	-0.1792358447909188	[263]	[359,137,249,101]	-3	hSpCas9	negative selection	7738844
57262171	57262194	17	+	27260156	PANC0327	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.14073549070409896	[279]	[216,289,267,314]	2	hSpCas9	negative selection	7738845
57257529	57257552	17	-	27260156	PANC0327	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.22913665889838208	[38]	[13,13,59,30]	-3	hSpCas9	negative selection	7803101
57258333	57258356	17	+	27260156	PANC0327	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.30231797449097203	[753]	[663,529,479,509]	-4	hSpCas9	negative selection	7803102
57258333	57258356	17	-	27260156	PANC0327	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.24426319158594567	[432]	[294,267,475,264]	-4	hSpCas9	negative selection	7803103
57257526	57257549	17	+	27260156	NCIH2009	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.059956969183991626	[1186]	[1846,1406,1569]	-1	hSpCas9	negative selection	7860094
57262172	57262195	17	-	27260156	NCIH2009	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.5413036280380168	[263]	[543,473,593]	7	hSpCas9	negative selection	7860095
57262171	57262194	17	+	27260156	NCIH2009	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.4481573185468833	[279]	[753,466,423]	6	hSpCas9	negative selection	7860096
57257529	57257552	17	-	27260156	NCIH2009	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	0.38219795913882537	[38]	[217,14,9]	5	hSpCas9	negative selection	7924352
57258333	57258356	17	+	27260156	NCIH2009	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.018765823646511248	[753]	[1342,801,1036]	0	hSpCas9	negative selection	7924353
57258333	57258356	17	-	27260156	NCIH2009	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.410963079325545	[432]	[686,350,373]	-5	hSpCas9	negative selection	7924354
57257526	57257549	17	+	27260156	NCIH1373	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.049407510036965085	[1186]	[1425,1184,1427,392]	0	hSpCas9	negative selection	7981345
57262172	57262195	17	-	27260156	NCIH1373	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.614500374309128	[263]	[394,618,391,97]	6	hSpCas9	negative selection	7981346
57262171	57262194	17	+	27260156	NCIH1373	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.1919864487226699	[279]	[321,171,307,82]	-2	hSpCas9	negative selection	7981347
57257529	57257552	17	-	27260156	NCIH1373	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-4.178480657980058	[38]	[1,0,2,0]	-9	hSpCas9	negative selection	8045603
57258333	57258356	17	+	27260156	NCIH1373	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.31113101057543524	[753]	[1007,895,1313,254]	3	hSpCas9	negative selection	8045604
57258333	57258356	17	-	27260156	NCIH1373	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-1.3803496255118717	[432]	[200,67,140,94]	-8	hSpCas9	negative selection	8045605
57257526	57257549	17	+	27260156	PATU8902	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.13886143562529285	[1186]	[1801,1008,1435,1792]	-1	hSpCas9	negative selection	8102596
57262172	57262195	17	-	27260156	PATU8902	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.05979260539614295	[263]	[518,608,271,126]	0	hSpCas9	negative selection	8102597
57262171	57262194	17	+	27260156	PATU8902	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-1.8461354267539245	[279]	[51,121,132,121]	-9	hSpCas9	negative selection	8102598
57257529	57257552	17	-	27260156	PATU8902	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-1.9128285679786794	[38]	[42,5,5,2]	-9	hSpCas9	negative selection	8166854
57258333	57258356	17	+	27260156	PATU8902	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.10524158505525061	[753]	[1282,1092,804,726]	-1	hSpCas9	negative selection	8166855
57258333	57258356	17	-	27260156	PATU8902	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.13902054623422366	[432]	[767,385,365,731]	-1	hSpCas9	negative selection	8166856
57257526	57257549	17	+	27260156	PANC1	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.291126040215282	[1186]	[824,1071,877,627]	-5	hSpCas9	negative selection	8223847
57262172	57262195	17	-	27260156	PANC1	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.13149608628877163	[263]	[317,281,218,185]	2	hSpCas9	negative selection	8223848
57262171	57262194	17	+	27260156	PANC1	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.24164195834651025	[279]	[210,248,82,264]	-4	hSpCas9	negative selection	8223849
57257529	57257552	17	-	27260156	PANC1	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-1.9305691580513766	[38]	[8,1,2,17]	-9	hSpCas9	negative selection	8288105
57258333	57258356	17	+	27260156	PANC1	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.005627972881314669	[753]	[463,763,667,710]	0	hSpCas9	negative selection	8288106
57258333	57258356	17	-	27260156	PANC1	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.4622076393022009	[432]	[301,429,215,174]	-6	hSpCas9	negative selection	8288107
57257526	57257549	17	+	27260156	PANC0813	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.02840090342431445	[1186]	[1476,1366,1472,1170]	0	hSpCas9	negative selection	8345098
57262172	57262195	17	-	27260156	PANC0813	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.2053802215548597	[263]	[290,279,509,343]	3	hSpCas9	negative selection	8345099
57262171	57262194	17	+	27260156	PANC0813	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.1838088918508699	[279]	[393,378,305,413]	3	hSpCas9	negative selection	8345100
57257529	57257552	17	-	27260156	PANC0813	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.837420850247832	[38]	[47,6,13,34]	-8	hSpCas9	negative selection	8409356
57258333	57258356	17	+	27260156	PANC0813	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.25635890790856003	[753]	[929,829,773,463]	-4	hSpCas9	negative selection	8409357
57258333	57258356	17	-	27260156	PANC0813	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.8700505974477456	[432]	[415,233,264,213]	-8	hSpCas9	negative selection	8409358
57257526	57257549	17	+	27260156	RDES	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.042343892826015805	[1186]	[1123,1107,1536,1608]	0	hSpCas9	negative selection	8466349
57262172	57262195	17	-	27260156	RDES	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	-0.14106528519204709	[263]	[210,263,246,404]	-2	hSpCas9	negative selection	8466350
57262171	57262194	17	+	27260156	RDES	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.14614402734787968	[279]	[339,274,259,580]	2	hSpCas9	negative selection	8466351
57257529	57257552	17	-	27260156	RDES	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.34869673114003374	[38]	[5,15,62,69]	-5	hSpCas9	negative selection	8530607
57258333	57258356	17	+	27260156	RDES	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.05314627518068138	[753]	[780,862,858,1129]	0	hSpCas9	negative selection	8530608
57258333	57258356	17	-	27260156	RDES	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.18152893037023937	[432]	[383,295,512,603]	-3	hSpCas9	negative selection	8530609
57257526	57257549	17	+	27260156	PC3	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.21035460163012898	[1186]	[647,1111,1535,1052]	-5	hSpCas9	negative selection	8587600
57262172	57262195	17	-	27260156	PC3	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.2031014517711036	[263]	[159,302,671,255]	4	hSpCas9	negative selection	8587601
57262171	57262194	17	+	27260156	PC3	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.2539515578475452	[279]	[267,133,864,269]	5	hSpCas9	negative selection	8587602
57257529	57257552	17	-	27260156	PC3	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.9655930673027235	[38]	[0,34,5,39]	-9	hSpCas9	negative selection	8651858
57258333	57258356	17	+	27260156	PC3	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.05977927372356118	[753]	[455,723,1349,640]	-1	hSpCas9	negative selection	8651859
57258333	57258356	17	-	27260156	PC3	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.376385623123045	[432]	[115,287,886,333]	-7	hSpCas9	negative selection	8651860
57257526	57257549	17	+	27260156	PATU8988T	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.16498682561006728	[1186]	[824,1252,940,1101]	-3	hSpCas9	negative selection	8708851
57262172	57262195	17	-	27260156	PATU8988T	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.40352809031841386	[263]	[258,401,419,267]	7	hSpCas9	negative selection	8708852
57262171	57262194	17	+	27260156	PATU8988T	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.17594288548499226	[279]	[402,217,293,298]	3	hSpCas9	negative selection	8708853
57257529	57257552	17	-	27260156	PATU8988T	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-1.602329638248018	[38]	[7,12,2,26]	-9	hSpCas9	negative selection	8773109
57258333	57258356	17	+	27260156	PATU8988T	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.17626700496826953	[753]	[756,832,987,703]	3	hSpCas9	negative selection	8773110
57258333	57258356	17	-	27260156	PATU8988T	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.05692187109709808	[432]	[514,263,352,469]	-1	hSpCas9	negative selection	8773111
57257526	57257549	17	+	27260156	T47D	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.1938016116526462	[1186]	[1208,1178,1255,1192]	-4	hSpCas9	negative selection	8830102
57262172	57262195	17	-	27260156	T47D	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.19310071991912336	[263]	[359,301,374,373]	4	hSpCas9	negative selection	8830103
57262171	57262194	17	+	27260156	T47D	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.10190770026638696	[279]	[373,330,386,307]	2	hSpCas9	negative selection	8830104
57257529	57257552	17	-	27260156	T47D	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.38121115011069184	[38]	[41,29,12,55]	-7	hSpCas9	negative selection	8894360
57258333	57258356	17	+	27260156	T47D	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.13688360749977269	[753]	[754,708,830,910]	-3	hSpCas9	negative selection	8894361
57258333	57258356	17	-	27260156	T47D	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.28933706490965205	[432]	[474,381,370,426]	-6	hSpCas9	negative selection	8894362
57257526	57257549	17	+	27260156	SU8686	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.0470710441327824	[1186]	[913,1070,1407,1207]	-1	hSpCas9	negative selection	8951353
57262172	57262195	17	-	27260156	SU8686	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.6115947133508606	[263]	[409,354,377,468]	8	hSpCas9	negative selection	8951354
57262171	57262194	17	+	27260156	SU8686	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.5242597901237793	[279]	[371,402,349,483]	8	hSpCas9	negative selection	8951355
57257529	57257552	17	-	27260156	SU8686	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-1.4274993428794787	[38]	[5,24,16,7]	-9	hSpCas9	negative selection	9015611
57258333	57258356	17	+	27260156	SU8686	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.08228318740809737	[753]	[687,680,880,966]	1	hSpCas9	negative selection	9015612
57258333	57258356	17	-	27260156	SU8686	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.34502527198490623	[432]	[364,304,315,368]	-5	hSpCas9	negative selection	9015613
57257526	57257549	17	+	27260156	SKES1	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.010943057570385495	[1186]	[964,1429,1253,1115]	0	hSpCas9	negative selection	9072604
57262172	57262195	17	-	27260156	SKES1	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	-0.10167602788645058	[263]	[248,386,237,135]	-2	hSpCas9	negative selection	9072605
57262171	57262194	17	+	27260156	SKES1	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.20155794982801245	[279]	[402,384,295,227]	4	hSpCas9	negative selection	9072606
57257529	57257552	17	-	27260156	SKES1	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	0.2821821165318159	[38]	[81,65,27,22]	6	hSpCas9	negative selection	9136862
57258333	57258356	17	+	27260156	SKES1	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.18650340755300915	[753]	[626,684,725,602]	-4	hSpCas9	negative selection	9136863
57258333	57258356	17	-	27260156	SKES1	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.16635989042631555	[432]	[489,385,389,294]	-4	hSpCas9	negative selection	9136864
57257526	57257549	17	+	27260156	TOV112D	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	0.051363475445885154	[1186]	[1250,1457,1298,981]	1	hSpCas9	negative selection	9193855
57262172	57262195	17	-	27260156	TOV112D	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.3512924798739072	[263]	[337,674,159,260]	6	hSpCas9	negative selection	9193856
57262171	57262194	17	+	27260156	TOV112D	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.0006343177951753098	[279]	[354,374,311,113]	0	hSpCas9	negative selection	9193857
57257529	57257552	17	-	27260156	TOV112D	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-2.149545820371471	[38]	[9,26,1,0]	-9	hSpCas9	negative selection	9258113
57258333	57258356	17	+	27260156	TOV112D	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.045339091459388525	[753]	[827,686,758,821]	0	hSpCas9	negative selection	9258114
57258333	57258356	17	-	27260156	TOV112D	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.1787060975470885	[432]	[255,531,499,272]	-3	hSpCas9	negative selection	9258115
57257526	57257549	17	+	27260156	TC71	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.24359179966008648	[1186]	[1026,1158,1009,1107]	-6	hSpCas9	negative selection	9315106
57262172	57262195	17	-	27260156	TC71	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.22750895941733007	[263]	[313,312,291,412]	5	hSpCas9	negative selection	9315107
57262171	57262194	17	+	27260156	TC71	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.23375467206091438	[279]	[399,384,336,284]	6	hSpCas9	negative selection	9315108
57257529	57257552	17	-	27260156	TC71	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-0.8048475028814499	[38]	[24,17,33,17]	-9	hSpCas9	negative selection	9379364
57258333	57258356	17	+	27260156	TC71	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	-0.05693406225857911	[753]	[705,776,837,786]	-1	hSpCas9	negative selection	9379365
57258333	57258356	17	-	27260156	TC71	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.14296477867063323	[432]	[431,370,475,398]	-4	hSpCas9	negative selection	9379366
57257526	57257549	17	+	27260156	TC32	viability	ATCCCACTACGAAACGCTCCAGG	MSI2	ENSG00000153944	-0.028585786792233447	[1186]	[1002,750,1440,1330]	0	hSpCas9	negative selection	9436357
57262172	57262195	17	-	27260156	TC32	viability	ACCTTGGGTTGCGCTCGACGAGG	MSI2	ENSG00000153944	0.15664583520369935	[263]	[246,172,298,426]	3	hSpCas9	negative selection	9436358
57262171	57262194	17	+	27260156	TC32	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.10578374903795928	[279]	[261,135,445,364]	2	hSpCas9	negative selection	9436359
57257529	57257552	17	-	27260156	TC32	viability	TTACCTGGAGCGTTTCGTAGTGG	MSI2	ENSG00000153944	-1.6293210280640649	[38]	[0,0,2,47]	-9	hSpCas9	negative selection	9500615
57258333	57258356	17	+	27260156	TC32	viability	CCATGAGTTAGATTCCAAGACGG	MSI2	ENSG00000153944	0.035473982028993434	[753]	[548,644,919,839]	0	hSpCas9	negative selection	9500616
57258333	57258356	17	-	27260156	TC32	viability	CCGTCTTGGAATCTAACTCATGG	MSI2	ENSG00000153944	-0.46937243149714125	[432]	[318,147,480,295]	-7	hSpCas9	negative selection	9500617
57256782	57256805	17	+	27869803	HPAFII	viability after 27 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	1.2615328051552495	[125]	[232,96,NaN]	9	hSpCas9	negative selection	9562002
57257103	57257126	17	+	27869803	HPAFII	viability after 27 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	0.9703736161405194	[153]	[252,79,NaN]	7	hSpCas9	negative selection	9562003
57262171	57262194	17	+	27869803	HPAFII	viability after 27 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.3361169764696763	[276]	[80,143,NaN]	-3	hSpCas9	negative selection	9562004
57616053	57616076	17	+	27869803	HPAFII	viability after 27 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-1.630356709214019	[249]	[66,21,NaN]	-8	hSpCas9	negative selection	9562006
57627240	57627263	17	+	27869803	HPAFII	viability after 27 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.7364216184941716	[944]	[1028,659,NaN]	6	hSpCas9	negative selection	9562007
57652106	57652129	17	+	27869803	HPAFII	viability after 27 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	0.5048813867930103	[348]	[459,93,NaN]	4	hSpCas9	negative selection	9562008
57256782	57256805	17	+	27869803	HPAFII	viability after 15 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	0.2562967799182566	[125]	[252,104,NaN]	3	hSpCas9	negative selection	9644451
57257103	57257126	17	+	27869803	HPAFII	viability after 15 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	0.7457117257831642	[153]	[361,224,NaN]	8	hSpCas9	negative selection	9644452
57262171	57262194	17	+	27869803	HPAFII	viability after 15 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.2678742754395507	[276]	[274,229,NaN]	-3	hSpCas9	negative selection	9644453
57616053	57616076	17	+	27869803	HPAFII	viability after 15 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.5248282582684031	[249]	[314,106,NaN]	-5	hSpCas9	negative selection	9644455
57627240	57627263	17	+	27869803	HPAFII	viability after 15 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.1615035870567214	[944]	[1717,773,NaN]	1	hSpCas9	negative selection	9644456
57652106	57652129	17	+	27869803	HPAFII	viability after 15 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.14858022096483853	[348]	[420,286,NaN]	-2	hSpCas9	negative selection	9644457
57256782	57256805	17	+	27869803	ASPC1	viability after 36 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	0.49005434616811633	[586]	[203,290,340]	5	hSpCas9	negative selection	9726900
57257103	57257126	17	+	27869803	ASPC1	viability after 36 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-0.05490200867420614	[352]	[107,130,114]	0	hSpCas9	negative selection	9726901
57262171	57262194	17	+	27869803	ASPC1	viability after 36 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.055838073074543026	[638]	[233,164,280]	0	hSpCas9	negative selection	9726902
57616053	57616076	17	+	27869803	ASPC1	viability after 36 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.1523403219466056	[559]	[47,162,273]	-1	hSpCas9	negative selection	9726904
57627240	57627263	17	+	27869803	ASPC1	viability after 36 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.6855339823887889	[1907]	[1159,1144,938]	6	hSpCas9	negative selection	9726905
57652106	57652129	17	+	27869803	ASPC1	viability after 36 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	-0.2322274374765924	[812]	[298,98,311]	-2	hSpCas9	negative selection	9726906
57256782	57256805	17	+	27869803	PATU8988S	viability after 35 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-0.2847355929105623	[457]	[116,185,NaN]	-3	hSpCas9	negative selection	9809349
57257103	57257126	17	+	27869803	PATU8988S	viability after 35 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	-0.12206260392327473	[314]	[148,83,NaN]	-1	hSpCas9	negative selection	9809350
57262171	57262194	17	+	27869803	PATU8988S	viability after 35 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	1.1663341571501704	[579]	[647,399,NaN]	9	hSpCas9	negative selection	9809351
57616053	57616076	17	+	27869803	PATU8988S	viability after 35 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.1363784764013743	[531]	[237,232,NaN]	1	hSpCas9	negative selection	9809353
57627240	57627263	17	+	27869803	PATU8988S	viability after 35 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.6573824883784827	[1695]	[788,1366,NaN]	7	hSpCas9	negative selection	9809354
57652106	57652129	17	+	27869803	PATU8988S	viability after 35 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	1.1272312908837765	[706]	[399,844,NaN]	9	hSpCas9	negative selection	9809355
57256782	57256805	17	+	27869803	PATU8988S	viability after 31 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	-0.48379063921482957	[457]	[101,166,NaN]	-5	hSpCas9	negative selection	9891798
57257103	57257126	17	+	27869803	PATU8988S	viability after 31 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	0.10240174267719648	[314]	[151,112,NaN]	1	hSpCas9	negative selection	9891799
57262171	57262194	17	+	27869803	PATU8988S	viability after 31 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.9590374083059614	[579]	[420,485,NaN]	9	hSpCas9	negative selection	9891800
57616053	57616076	17	+	27869803	PATU8988S	viability after 31 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.3576633905181845	[531]	[132,206,NaN]	-4	hSpCas9	negative selection	9891802
57627240	57627263	17	+	27869803	PATU8988S	viability after 31 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.5618032742315342	[1695]	[655,1433,NaN]	6	hSpCas9	negative selection	9891803
57652106	57652129	17	+	27869803	PATU8988S	viability after 31 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	1.16947199648679	[706]	[352,991,NaN]	9	hSpCas9	negative selection	9891804
57256782	57256805	17	+	27869803	HPAFII	viability after 35 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	0.21225707358527401	[125]	[103,39,NaN]	1	hSpCas9	negative selection	9974247
57257103	57257126	17	+	27869803	HPAFII	viability after 35 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	0.5521382543041249	[153]	[150,72,NaN]	3	hSpCas9	negative selection	9974248
57262171	57262194	17	+	27869803	HPAFII	viability after 35 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.3305747266410184	[276]	[79,146,NaN]	-2	hSpCas9	negative selection	9974249
57616053	57616076	17	+	27869803	HPAFII	viability after 35 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-1.7785641261041842	[249]	[50,20,NaN]	-7	hSpCas9	negative selection	9974251
57627240	57627263	17	+	27869803	HPAFII	viability after 35 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.8548698410633626	[944]	[987,726,NaN]	5	hSpCas9	negative selection	9974252
57652106	57652129	17	+	27869803	HPAFII	viability after 35 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	0.9872099349415899	[348]	[480,202,NaN]	6	hSpCas9	negative selection	9974253
57256782	57256805	17	+	27869803	HPAFII	viability after 31 days	AACGACTCCCAGCACGACCCCGG	MSI2	ENSG00000153944	0.69745344149704	[125]	[151,73,NaN]	5	hSpCas9	negative selection	10056696
57257103	57257126	17	+	27869803	HPAFII	viability after 31 days	TGTTTATCGGTGGACTGAGCTGG	MSI2	ENSG00000153944	1.0315095938444763	[153]	[280,62,NaN]	7	hSpCas9	negative selection	10056697
57262171	57262194	17	+	27869803	HPAFII	viability after 31 days	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.4049068257721365	[276]	[81,155,NaN]	-3	hSpCas9	negative selection	10056698
57616053	57616076	17	+	27869803	HPAFII	viability after 31 days	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-2.0398069404605303	[249]	[47,18,NaN]	-8	hSpCas9	negative selection	10056700
57627240	57627263	17	+	27869803	HPAFII	viability after 31 days	TTCGTGGCGACCTATGGCCGTGG	MSI2	ENSG00000153944	0.7588425033469337	[944]	[984,801,NaN]	5	hSpCas9	negative selection	10056701
57652106	57652129	17	+	27869803	HPAFII	viability after 31 days	AGCAGCGGCTTATGGACCAGTGG	MSI2	ENSG00000153944	0.5976200750344001	[348]	[438,140,NaN]	4	hSpCas9	negative selection	10056702
57529703	57529726	17	+	28162770	P31FUJ	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.5180781363304551	[226]	[381]	6	hSpCas9	negative selection	10194967
57615995	57616018	17	+	28162770	P31FUJ	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.5173826787838016	[1433]	[2411]	6	hSpCas9	negative selection	10194968
57627257	57627280	17	-	28162770	P31FUJ	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	0.37640784255345494	[117]	[179]	4	hSpCas9	negative selection	10194969
57401414	57401437	17	+	28162770	P31FUJ	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.32761811204398583	[414]	[611]	3	hSpCas9	negative selection	10194970
57258330	57258353	17	-	28162770	P31FUJ	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.09508334576938315	[579]	[727]	1	hSpCas9	negative selection	10194971
57262171	57262194	17	+	28162770	P31FUJ	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.309990842062838	[161]	[235]	3	hSpCas9	negative selection	10194972
57616009	57616032	17	-	28162770	P31FUJ	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	0.11642023915755173	[554]	[706]	1	hSpCas9	negative selection	10194973
57616032	57616055	17	+	28162770	P31FUJ	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	0.8180220546633039	[250]	[519]	8	hSpCas9	negative selection	10194974
57616053	57616076	17	+	28162770	P31FUJ	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.4899026966266578	[182]	[301]	5	hSpCas9	negative selection	10194975
57401450	57401473	17	+	28162770	P31FUJ	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	1.0735850395772055	[223]	[553]	9	hSpCas9	negative selection	10194976
57529703	57529726	17	+	28162770	TF1	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	NaN	[NaN]	[184]	1	hSpCas9	negative selection	10364333
57615995	57616018	17	+	28162770	TF1	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	NaN	[NaN]	[1763]	1	hSpCas9	negative selection	10364334
57627257	57627280	17	-	28162770	TF1	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	NaN	[NaN]	[229]	1	hSpCas9	negative selection	10364335
57401414	57401437	17	+	28162770	TF1	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	NaN	[NaN]	[199]	1	hSpCas9	negative selection	10364336
57258330	57258353	17	-	28162770	TF1	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	NaN	[NaN]	[444]	1	hSpCas9	negative selection	10364337
57262171	57262194	17	+	28162770	TF1	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10364338
57616009	57616032	17	-	28162770	TF1	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	NaN	[NaN]	[306]	1	hSpCas9	negative selection	10364339
57616032	57616055	17	+	28162770	TF1	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	NaN	[NaN]	[217]	1	hSpCas9	negative selection	10364340
57616053	57616076	17	+	28162770	TF1	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10364341
57401450	57401473	17	+	28162770	TF1	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	NaN	[NaN]	[181]	1	hSpCas9	negative selection	10364342
57529703	57529726	17	+	28162770	SKM1	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.6234094503003572	[46]	[127]	6	hSpCas9	negative selection	10533699
57615995	57616018	17	+	28162770	SKM1	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.4470314484332314	[299]	[722]	4	hSpCas9	negative selection	10533700
57627257	57627280	17	-	28162770	SKM1	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	0.13952415416335878	[37]	[73]	1	hSpCas9	negative selection	10533701
57401414	57401437	17	+	28162770	SKM1	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.3894159975323144	[142]	[192]	-3	hSpCas9	negative selection	10533702
57258330	57258353	17	-	28162770	SKM1	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	-0.11839470080223014	[174]	[284]	-1	hSpCas9	negative selection	10533703
57262171	57262194	17	+	28162770	SKM1	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.15005589570620942	[58]	[93]	-1	hSpCas9	negative selection	10533704
57616009	57616032	17	-	28162770	SKM1	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	-0.025535092107137558	[113]	[197]	0	hSpCas9	negative selection	10533705
57616032	57616055	17	+	28162770	SKM1	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	-0.12539384147194038	[57]	[93]	-1	hSpCas9	negative selection	10533706
57616053	57616076	17	+	28162770	SKM1	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.2640062449011187	[35]	[52]	-2	hSpCas9	negative selection	10533707
57401450	57401473	17	+	28162770	SKM1	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	0.9632594531849819	[46]	[161]	8	hSpCas9	negative selection	10533708
57529703	57529726	17	+	28162770	SKM1	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.6234094503003572	[46]	[127]	6	hSpCas9	negative selection	10703065
57615995	57616018	17	+	28162770	SKM1	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.4470314484332314	[299]	[722]	4	hSpCas9	negative selection	10703066
57627257	57627280	17	-	28162770	SKM1	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	0.13952415416335878	[37]	[73]	1	hSpCas9	negative selection	10703067
57401414	57401437	17	+	28162770	SKM1	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.3894159975323144	[142]	[192]	-3	hSpCas9	negative selection	10703068
57258330	57258353	17	-	28162770	SKM1	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	-0.11839470080223014	[174]	[284]	-1	hSpCas9	negative selection	10703069
57262171	57262194	17	+	28162770	SKM1	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.15005589570620942	[58]	[93]	-1	hSpCas9	negative selection	10703070
57616009	57616032	17	-	28162770	SKM1	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	-0.025535092107137558	[113]	[197]	0	hSpCas9	negative selection	10703071
57616032	57616055	17	+	28162770	SKM1	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	-0.12539384147194038	[57]	[93]	-1	hSpCas9	negative selection	10703072
57616053	57616076	17	+	28162770	SKM1	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.2640062449011187	[35]	[52]	-2	hSpCas9	negative selection	10703073
57401450	57401473	17	+	28162770	SKM1	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	0.9632594531849819	[46]	[161]	8	hSpCas9	negative selection	10703074
57529703	57529726	17	+	28162770	PL21	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	-1.089367002705665	[175]	[35]	-6	hSpCas9	negative selection	10872431
57615995	57616018	17	+	28162770	PL21	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.11775728690898735	[1062]	[501]	1	hSpCas9	negative selection	10872432
57627257	57627280	17	-	28162770	PL21	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	1.4538962067351031	[103]	[123]	9	hSpCas9	negative selection	10872433
57401414	57401437	17	+	28162770	PL21	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.3242813442967851	[629]	[218]	-2	hSpCas9	negative selection	10872434
57258330	57258353	17	-	28162770	PL21	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	-0.33037510220945987	[727]	[251]	-2	hSpCas9	negative selection	10872435
57262171	57262194	17	+	28162770	PL21	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.013985190863527397	[231]	[99]	0	hSpCas9	negative selection	10872436
57616009	57616032	17	-	28162770	PL21	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	0.6194391406223236	[337]	[225]	5	hSpCas9	negative selection	10872437
57616032	57616055	17	+	28162770	PL21	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	-0.14592014287094032	[210]	[82]	-1	hSpCas9	negative selection	10872438
57616053	57616076	17	+	28162770	PL21	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.08406881444888348	[150]	[61]	0	hSpCas9	negative selection	10872439
57401450	57401473	17	+	28162770	PL21	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	-0.09359158856739014	[151]	[61]	0	hSpCas9	negative selection	10872440
57529703	57529726	17	+	28162770	P31FUJ	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.5180781363304551	[226]	[381]	6	hSpCas9	negative selection	11041797
57615995	57616018	17	+	28162770	P31FUJ	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.5173826787838016	[1433]	[2411]	6	hSpCas9	negative selection	11041798
57627257	57627280	17	-	28162770	P31FUJ	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	0.37640784255345494	[117]	[179]	4	hSpCas9	negative selection	11041799
57401414	57401437	17	+	28162770	P31FUJ	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.32761811204398583	[414]	[611]	3	hSpCas9	negative selection	11041800
57258330	57258353	17	-	28162770	P31FUJ	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.09508334576938315	[579]	[727]	1	hSpCas9	negative selection	11041801
57262171	57262194	17	+	28162770	P31FUJ	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.309990842062838	[161]	[235]	3	hSpCas9	negative selection	11041802
57616009	57616032	17	-	28162770	P31FUJ	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	0.11642023915755173	[554]	[706]	1	hSpCas9	negative selection	11041803
57616032	57616055	17	+	28162770	P31FUJ	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	0.8180220546633039	[250]	[519]	8	hSpCas9	negative selection	11041804
57616053	57616076	17	+	28162770	P31FUJ	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.4899026966266578	[182]	[301]	5	hSpCas9	negative selection	11041805
57401450	57401473	17	+	28162770	P31FUJ	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	1.0735850395772055	[223]	[553]	9	hSpCas9	negative selection	11041806
57529703	57529726	17	+	28162770	OCIAML5	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	1.3022615755272968	[92]	[413]	9	hSpCas9	negative selection	11211163
57615995	57616018	17	+	28162770	OCIAML5	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.8183820930456158	[758]	[2415]	7	hSpCas9	negative selection	11211164
57627257	57627280	17	-	28162770	OCIAML5	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	0.16423524146510338	[43]	[88]	1	hSpCas9	negative selection	11211165
57401414	57401437	17	+	28162770	OCIAML5	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.0908121502356507	[321]	[618]	0	hSpCas9	negative selection	11211166
57258330	57258353	17	-	28162770	OCIAML5	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.5186405579590501	[441]	[1142]	4	hSpCas9	negative selection	11211167
57262171	57262194	17	+	28162770	OCIAML5	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	1.3586440454248154	[61]	[286]	9	hSpCas9	negative selection	11211168
57616009	57616032	17	-	28162770	OCIAML5	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	0.035723925549978164	[293]	[543]	0	hSpCas9	negative selection	11211169
57616032	57616055	17	+	28162770	OCIAML5	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	0.8798722062273765	[114]	[381]	7	hSpCas9	negative selection	11211170
57616053	57616076	17	+	28162770	OCIAML5	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.10644910644488198	[132]	[222]	-1	hSpCas9	negative selection	11211171
57401450	57401473	17	+	28162770	OCIAML5	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	-0.2891303764728396	[175]	[259]	-2	hSpCas9	negative selection	11211172
57529703	57529726	17	+	28162770	EOL1	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.6654605502534034	[364]	[304]	6	hSpCas9	negative selection	11380529
57615995	57616018	17	+	28162770	EOL1	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.29387521713055165	[1490]	[962]	2	hSpCas9	negative selection	11380530
57627257	57627280	17	-	28162770	EOL1	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	0.9612595499270558	[193]	[198]	8	hSpCas9	negative selection	11380531
57401414	57401437	17	+	28162770	EOL1	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.3449129034226923	[809]	[335]	-3	hSpCas9	negative selection	11380532
57258330	57258353	17	-	28162770	EOL1	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	-0.23641079304891788	[1202]	[537]	-2	hSpCas9	negative selection	11380533
57262171	57262194	17	+	28162770	EOL1	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.3621908948545278	[404]	[165]	-3	hSpCas9	negative selection	11380534
57616009	57616032	17	-	28162770	EOL1	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	-1.6541557386789392	[459]	[76]	-8	hSpCas9	negative selection	11380535
57616032	57616055	17	+	28162770	EOL1	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	-0.6964839838581434	[242]	[78]	-5	hSpCas9	negative selection	11380536
57616053	57616076	17	+	28162770	EOL1	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.4931788152359493	[178]	[66]	-4	hSpCas9	negative selection	11380537
57401450	57401473	17	+	28162770	EOL1	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	1.0984156424823022	[202]	[228]	8	hSpCas9	negative selection	11380538
57529703	57529726	17	+	28162770	MOLM13	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.271969171569322	[377]	[329]	2	hSpCas9	negative selection	11549895
57615995	57616018	17	+	28162770	MOLM13	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.8326328494706186	[1473]	[1897]	6	hSpCas9	negative selection	11549896
57627257	57627280	17	-	28162770	MOLM13	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	0.7983625855649499	[201]	[253]	6	hSpCas9	negative selection	11549897
57401414	57401437	17	+	28162770	MOLM13	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.20961992387953443	[664]	[555]	1	hSpCas9	negative selection	11549898
57258330	57258353	17	-	28162770	MOLM13	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.017637189681677157	[939]	[687]	0	hSpCas9	negative selection	11549899
57262171	57262194	17	+	28162770	MOLM13	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.009432395988607716	[283]	[203]	0	hSpCas9	negative selection	11549900
57616009	57616032	17	-	28162770	MOLM13	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	-0.1112322405875169	[492]	[329]	0	hSpCas9	negative selection	11549901
57616032	57616055	17	+	28162770	MOLM13	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	-0.022294894424477518	[242]	[172]	0	hSpCas9	negative selection	11549902
57616053	57616076	17	+	28162770	MOLM13	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-2.1595977358231346	[240]	[38]	-7	hSpCas9	negative selection	11549903
57401450	57401473	17	+	28162770	MOLM13	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	0.4729603710920008	[283]	[284]	3	hSpCas9	negative selection	11549904
57529703	57529726	17	+	28162770	HEL	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.11817092933136963	[268]	[186]	0	hSpCas9	negative selection	11719261
57615995	57616018	17	+	28162770	HEL	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.422869114317197	[1237]	[1062]	3	hSpCas9	negative selection	11719262
57627257	57627280	17	-	28162770	HEL	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	1.239242954604204	[165]	[250]	9	hSpCas9	negative selection	11719263
57401414	57401437	17	+	28162770	HEL	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.38415375904052795	[517]	[432]	3	hSpCas9	negative selection	11719264
57258330	57258353	17	-	28162770	HEL	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.27623770102573375	[944]	[732]	2	hSpCas9	negative selection	11719265
57262171	57262194	17	+	28162770	HEL	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.26368062982707974	[263]	[202]	2	hSpCas9	negative selection	11719266
57616009	57616032	17	-	28162770	HEL	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	-0.205258074554593	[377]	[209]	-1	hSpCas9	negative selection	11719267
57616032	57616055	17	+	28162770	HEL	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	-0.3987378039758023	[246]	[119]	-3	hSpCas9	negative selection	11719268
57616053	57616076	17	+	28162770	HEL	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.9895293834991559	[185]	[59]	-6	hSpCas9	negative selection	11719269
57401450	57401473	17	+	28162770	HEL	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	0.9586431392599493	[191]	[238]	8	hSpCas9	negative selection	11719270
57529703	57529726	17	+	28162770	MV411	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.049837590897614636	[249]	[217]	0	hSpCas9	negative selection	11888627
57615995	57616018	17	+	28162770	MV411	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.26583281873796194	[1090]	[1104]	2	hSpCas9	negative selection	11888628
57627257	57627280	17	-	28162770	MV411	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	0.4079022229760213	[118]	[132]	3	hSpCas9	negative selection	11888629
57401414	57401437	17	+	28162770	MV411	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.8935132745856282	[418]	[189]	-6	hSpCas9	negative selection	11888630
57258330	57258353	17	-	28162770	MV411	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.37527859355383497	[571]	[624]	3	hSpCas9	negative selection	11888631
57262171	57262194	17	+	28162770	MV411	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.529330983867885	[189]	[230]	5	hSpCas9	negative selection	11888632
57616009	57616032	17	-	28162770	MV411	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	0.12879305428415666	[379]	[349]	1	hSpCas9	negative selection	11888633
57616032	57616055	17	+	28162770	MV411	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	0.5024791658630384	[180]	[215]	4	hSpCas9	negative selection	11888634
57616053	57616076	17	+	28162770	MV411	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.7529655840095265	[111]	[158]	6	hSpCas9	negative selection	11888635
57401450	57401473	17	+	28162770	MV411	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	0.7153606303137121	[153]	[212]	6	hSpCas9	negative selection	11888636
57529703	57529726	17	+	28162770	MONOMAC1	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	-0.3849697976526287	[130]	[114]	-3	hSpCas9	negative selection	12057993
57615995	57616018	17	+	28162770	MONOMAC1	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.03913809870829743	[758]	[893]	0	hSpCas9	negative selection	12057994
57627257	57627280	17	-	28162770	MONOMAC1	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	-0.7732291381529777	[81]	[54]	-6	hSpCas9	negative selection	12057995
57401414	57401437	17	+	28162770	MONOMAC1	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.5035897160600002	[349]	[282]	-4	hSpCas9	negative selection	12057996
57258330	57258353	17	-	28162770	MONOMAC1	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.0785975955538738	[417]	[505]	0	hSpCas9	negative selection	12057997
57262171	57262194	17	+	28162770	MONOMAC1	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.31142751618755904	[141]	[201]	3	hSpCas9	negative selection	12057998
57616009	57616032	17	-	28162770	MONOMAC1	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	-0.38090103945973963	[233]	[205]	-3	hSpCas9	negative selection	12057999
57616032	57616055	17	+	28162770	MONOMAC1	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	-0.5362429333787517	[104]	[82]	-4	hSpCas9	negative selection	12058000
57616053	57616076	17	+	28162770	MONOMAC1	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.9063927425958518	[73]	[158]	8	hSpCas9	negative selection	12058001
57401450	57401473	17	+	28162770	MONOMAC1	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	-0.12565221382278835	[137]	[144]	-1	hSpCas9	negative selection	12058002
57529703	57529726	17	+	28162770	OCIAML2	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	1.1067990027935877	[31]	[381]	9	hSpCas9	negative selection	12227359
57615995	57616018	17	+	28162770	OCIAML2	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.4790709988050077	[196]	[1521]	4	hSpCas9	negative selection	12227360
57627257	57627280	17	-	28162770	OCIAML2	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	-0.3581550959837488	[36]	[159]	-3	hSpCas9	negative selection	12227361
57401414	57401437	17	+	28162770	OCIAML2	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	0.9302496110400229	[79]	[844]	8	hSpCas9	negative selection	12227362
57258330	57258353	17	-	28162770	OCIAML2	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.5439577109808851	[122]	[993]	5	hSpCas9	negative selection	12227363
57262171	57262194	17	+	28162770	OCIAML2	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	-0.21989277821175185	[53]	[256]	-2	hSpCas9	negative selection	12227364
57616009	57616032	17	-	28162770	OCIAML2	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	0.1329965197440307	[63]	[388]	1	hSpCas9	negative selection	12227365
57616032	57616055	17	+	28162770	OCIAML2	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	0.3685739628547828	[31]	[228]	3	hSpCas9	negative selection	12227366
57616053	57616076	17	+	28162770	OCIAML2	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	0.2537357321444114	[22]	[151]	2	hSpCas9	negative selection	12227367
57401450	57401473	17	+	28162770	OCIAML2	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	0.6734165443745456	[24]	[220]	6	hSpCas9	negative selection	12227368
57529703	57529726	17	+	28162770	OCIAML3	viability	AAAACTACCAACAGGCACAGAGG	MSI2	ENSG00000153944	0.4001632808736392	[61]	[246]	4	hSpCas9	negative selection	12396725
57615995	57616018	17	+	28162770	OCIAML3	viability	AAGAAGTCATGTTCCCACCTGGG	MSI2	ENSG00000153944	0.13371974698670508	[281]	[933]	1	hSpCas9	negative selection	12396726
57627257	57627280	17	-	28162770	OCIAML3	viability	GAGCAAATCCGGGGTAGCCACGG	MSI2	ENSG00000153944	1.2257843849716639	[32]	[232]	8	hSpCas9	negative selection	12396727
57401414	57401437	17	+	28162770	OCIAML3	viability	GTTATCTGCGAACACAGTAGTGG	MSI2	ENSG00000153944	-0.4265508944726003	[129]	[291]	-3	hSpCas9	negative selection	12396728
57258330	57258353	17	-	28162770	OCIAML3	viability	TCTTGGAATCTAACTCATGGTGG	MSI2	ENSG00000153944	0.24006462010922025	[213]	[762]	2	hSpCas9	negative selection	12396729
57262171	57262194	17	+	28162770	OCIAML3	viability	TCCTCGTCGAGCGCAACCCAAGG	MSI2	ENSG00000153944	0.4384138373682143	[54]	[224]	4	hSpCas9	negative selection	12396730
57616009	57616032	17	-	28162770	OCIAML3	viability	GCCCGGCCTCTTGTCCCAGGTGG	MSI2	ENSG00000153944	-0.08575131308513362	[102]	[292]	0	hSpCas9	negative selection	12396731
57616032	57616055	17	+	28162770	OCIAML3	viability	CCGGGGACTGCCTTACACCATGG	MSI2	ENSG00000153944	-0.29761463754393835	[56]	[139]	-2	hSpCas9	negative selection	12396732
57616053	57616076	17	+	28162770	OCIAML3	viability	GGACGCGTTCATGCTTGGCATGG	MSI2	ENSG00000153944	-0.6595959819517401	[44]	[85]	-5	hSpCas9	negative selection	12396733
57401450	57401473	17	+	28162770	OCIAML3	viability	ATATTTCGAGCAGTTTGGCAAGG	MSI2	ENSG00000153944	-0.4209429313512835	[50]	[114]	-3	hSpCas9	negative selection	12396734