Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4629
• Symbol:MYH11
• Description:myosin heavy chain 11

DataSource: http://genomecrispr.dkfz.de/#!/results/MYH11

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
15745159	15745182	16	-	26472758	Jiyoye	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.9601477679825925	[151]	[222]	6	hSpCas9	negative selection	104421
15830313	15830336	CHR_HSCHR16_1_CTG1	-	26472758	Jiyoye	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000276480	0.9601477679825925	[151]	[222]	6	hSpCas9	negative selection	104422
15724733	15724756	16	-	26472758	Jiyoye	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	-1.0875893102437049	[61]	[21]	-6	hSpCas9	negative selection	104423
15809887	15809910	CHR_HSCHR16_1_CTG1	-	26472758	Jiyoye	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000276480	-1.0875893102437049	[61]	[21]	-6	hSpCas9	negative selection	104424
15720952	15720975	16	-	26472758	Jiyoye	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.10499122191692623	[253]	[205]	0	hSpCas9	negative selection	104425
15806106	15806129	CHR_HSCHR16_1_CTG1	-	26472758	Jiyoye	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000276480	0.10499122191692623	[253]	[205]	0	hSpCas9	negative selection	104426
15923228	15923251	CHR_HSCHR16_1_CTG1	-	26472758	Jiyoye	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000276480	-0.47993056208819307	[171]	[92]	-3	hSpCas9	negative selection	104427
15838096	15838119	16	-	26472758	Jiyoye	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	-0.47993056208819307	[171]	[92]	-3	hSpCas9	negative selection	104428
15838042	15838065	16	-	26472758	Jiyoye	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	0.10284134663324912	[162]	[131]	0	hSpCas9	negative selection	104429
15923174	15923197	CHR_HSCHR16_1_CTG1	-	26472758	Jiyoye	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000276480	0.10284134663324912	[162]	[131]	0	hSpCas9	negative selection	104430
15771611	15771634	16	-	26472758	Jiyoye	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.4285490322984402	[133]	[135]	3	hSpCas9	negative selection	104431
15856764	15856787	CHR_HSCHR16_1_CTG1	-	26472758	Jiyoye	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000276480	0.4285490322984402	[133]	[135]	3	hSpCas9	negative selection	104432
15763817	15763840	16	-	26472758	Jiyoye	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	-0.1103591916949922	[208]	[145]	-1	hSpCas9	negative selection	104433
15848971	15848994	CHR_HSCHR16_1_CTG1	-	26472758	Jiyoye	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000276480	-0.1103591916949922	[208]	[145]	-1	hSpCas9	negative selection	104434
15844768	15844791	CHR_HSCHR16_1_CTG1	+	26472758	Jiyoye	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000276480	2.001918903019615	[48]	[147]	8	hSpCas9	negative selection	104435
15759614	15759637	16	+	26472758	Jiyoye	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	2.001918903019615	[48]	[147]	8	hSpCas9	negative selection	104436
15756486	15756509	16	+	26472758	Jiyoye	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	1.6847093570347822	[65]	[159]	8	hSpCas9	negative selection	104437
15841640	15841663	CHR_HSCHR16_1_CTG1	+	26472758	Jiyoye	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000276480	1.6847093570347822	[65]	[159]	8	hSpCas9	negative selection	104438
15745159	15745182	16	-	26472758	KBM7	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.7235874022547667	[957,865]	[662,747]	7	hSpCas9	negative selection	295539
15830313	15830336	CHR_HSCHR16_1_CTG1	-	26472758	KBM7	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000276480	0.7235874022547667	[957,865]	[662,747]	7	hSpCas9	negative selection	295540
15724733	15724756	16	-	26472758	KBM7	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	0.3836134486027425	[136,118]	[156,7]	4	hSpCas9	negative selection	295541
15809887	15809910	CHR_HSCHR16_1_CTG1	-	26472758	KBM7	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000276480	0.3836134486027425	[136,118]	[156,7]	4	hSpCas9	negative selection	295542
15720952	15720975	16	-	26472758	KBM7	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.83285974717183	[620,573]	[437,556]	8	hSpCas9	negative selection	295543
15806106	15806129	CHR_HSCHR16_1_CTG1	-	26472758	KBM7	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000276480	0.83285974717183	[620,573]	[437,556]	8	hSpCas9	negative selection	295544
15923228	15923251	CHR_HSCHR16_1_CTG1	-	26472758	KBM7	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000276480	0.06972800342288196	[534,351]	[152,270]	0	hSpCas9	negative selection	295545
15838096	15838119	16	-	26472758	KBM7	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	0.06972800342288196	[534,351]	[152,270]	0	hSpCas9	negative selection	295546
15838042	15838065	16	-	26472758	KBM7	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-0.2270791304733063	[712,650]	[282,265]	-2	hSpCas9	negative selection	295547
15923174	15923197	CHR_HSCHR16_1_CTG1	-	26472758	KBM7	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000276480	-0.2270791304733063	[712,650]	[282,265]	-2	hSpCas9	negative selection	295548
15771611	15771634	16	-	26472758	KBM7	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.46322776523677206	[597,363]	[247,356]	5	hSpCas9	negative selection	295549
15856764	15856787	CHR_HSCHR16_1_CTG1	-	26472758	KBM7	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000276480	0.46322776523677206	[597,363]	[247,356]	5	hSpCas9	negative selection	295550
15763817	15763840	16	-	26472758	KBM7	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	0.09175503474674829	[797,851]	[439,395]	0	hSpCas9	negative selection	295551
15848971	15848994	CHR_HSCHR16_1_CTG1	-	26472758	KBM7	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000276480	0.09175503474674829	[797,851]	[439,395]	0	hSpCas9	negative selection	295552
15844768	15844791	CHR_HSCHR16_1_CTG1	+	26472758	KBM7	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000276480	0.5215590898488194	[371,237]	[159,239]	5	hSpCas9	negative selection	295553
15759614	15759637	16	+	26472758	KBM7	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.5215590898488194	[371,237]	[159,239]	5	hSpCas9	negative selection	295554
15756486	15756509	16	+	26472758	KBM7	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	0.4457922849682724	[553,444]	[272,357]	5	hSpCas9	negative selection	295555
15841640	15841663	CHR_HSCHR16_1_CTG1	+	26472758	KBM7	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000276480	0.4457922849682724	[553,444]	[272,357]	5	hSpCas9	negative selection	295556
15745159	15745182	16	-	26472758	Raji	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	-0.1586533586217176	[480]	[99]	-1	hSpCas9	negative selection	486657
15830313	15830336	CHR_HSCHR16_1_CTG1	-	26472758	Raji	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000276480	-0.1586533586217176	[480]	[99]	-1	hSpCas9	negative selection	486658
15724733	15724756	16	-	26472758	Raji	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	2.637898252072379	[17]	[25]	9	hSpCas9	negative selection	486659
15809887	15809910	CHR_HSCHR16_1_CTG1	-	26472758	Raji	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000276480	2.637898252072379	[17]	[25]	9	hSpCas9	negative selection	486660
15720952	15720975	16	-	26472758	Raji	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	1.248559598334294	[320]	[176]	9	hSpCas9	negative selection	486661
15806106	15806129	CHR_HSCHR16_1_CTG1	-	26472758	Raji	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000276480	1.248559598334294	[320]	[176]	9	hSpCas9	negative selection	486662
15923228	15923251	CHR_HSCHR16_1_CTG1	-	26472758	Raji	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000276480	1.9515888627661753	[126]	[113]	9	hSpCas9	negative selection	486663
15838096	15838119	16	-	26472758	Raji	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	1.9515888627661753	[126]	[113]	9	hSpCas9	negative selection	486664
15838042	15838065	16	-	26472758	Raji	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-0.5050597017696639	[317]	[51]	-4	hSpCas9	negative selection	486665
15923174	15923197	CHR_HSCHR16_1_CTG1	-	26472758	Raji	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000276480	-0.5050597017696639	[317]	[51]	-4	hSpCas9	negative selection	486666
15771611	15771634	16	-	26472758	Raji	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	1.1405503993087989	[214]	[109]	8	hSpCas9	negative selection	486667
15856764	15856787	CHR_HSCHR16_1_CTG1	-	26472758	Raji	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000276480	1.1405503993087989	[214]	[109]	8	hSpCas9	negative selection	486668
15763817	15763840	16	-	26472758	Raji	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	0.449303105448428	[343]	[108]	4	hSpCas9	negative selection	486669
15848971	15848994	CHR_HSCHR16_1_CTG1	-	26472758	Raji	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000276480	0.449303105448428	[343]	[108]	4	hSpCas9	negative selection	486670
15844768	15844791	CHR_HSCHR16_1_CTG1	+	26472758	Raji	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000276480	0.9939254855903157	[237]	[109]	8	hSpCas9	negative selection	486671
15759614	15759637	16	+	26472758	Raji	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.9939254855903157	[237]	[109]	8	hSpCas9	negative selection	486672
15756486	15756509	16	+	26472758	Raji	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	0.48589515862732935	[359]	[116]	4	hSpCas9	negative selection	486673
15841640	15841663	CHR_HSCHR16_1_CTG1	+	26472758	Raji	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000276480	0.48589515862732935	[359]	[116]	4	hSpCas9	negative selection	486674
15745159	15745182	16	-	26472758	K562	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.8001166338824084	[829]	[1219]	6	hSpCas9	negative selection	677775
15830313	15830336	CHR_HSCHR16_1_CTG1	-	26472758	K562	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000276480	0.8001166338824084	[829]	[1219]	6	hSpCas9	negative selection	677776
15724733	15724756	16	-	26472758	K562	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	-0.585656270891241	[111]	[62]	-4	hSpCas9	negative selection	677777
15809887	15809910	CHR_HSCHR16_1_CTG1	-	26472758	K562	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000276480	-0.585656270891241	[111]	[62]	-4	hSpCas9	negative selection	677778
15720952	15720975	16	-	26472758	K562	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	1.0625000563171092	[535]	[944]	8	hSpCas9	negative selection	677779
15806106	15806129	CHR_HSCHR16_1_CTG1	-	26472758	K562	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000276480	1.0625000563171092	[535]	[944]	8	hSpCas9	negative selection	677780
15923228	15923251	CHR_HSCHR16_1_CTG1	-	26472758	K562	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000276480	-0.1448193021803413	[350]	[267]	-1	hSpCas9	negative selection	677781
15838096	15838119	16	-	26472758	K562	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	-0.1448193021803413	[350]	[267]	-1	hSpCas9	negative selection	677782
15838042	15838065	16	-	26472758	K562	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-1.3705563421211489	[679]	[221]	-6	hSpCas9	negative selection	677783
15923174	15923197	CHR_HSCHR16_1_CTG1	-	26472758	K562	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000276480	-1.3705563421211489	[679]	[221]	-6	hSpCas9	negative selection	677784
15771611	15771634	16	-	26472758	K562	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	1.287555231044445	[312]	[644]	9	hSpCas9	negative selection	677785
15856764	15856787	CHR_HSCHR16_1_CTG1	-	26472758	K562	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000276480	1.287555231044445	[312]	[644]	9	hSpCas9	negative selection	677786
15763817	15763840	16	-	26472758	K562	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	0.5202629405515473	[597]	[723]	4	hSpCas9	negative selection	677787
15848971	15848994	CHR_HSCHR16_1_CTG1	-	26472758	K562	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000276480	0.5202629405515473	[597]	[723]	4	hSpCas9	negative selection	677788
15844768	15844791	CHR_HSCHR16_1_CTG1	+	26472758	K562	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000276480	0.06023974254389258	[266]	[234]	0	hSpCas9	negative selection	677789
15759614	15759637	16	+	26472758	K562	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.06023974254389258	[266]	[234]	0	hSpCas9	negative selection	677790
15756486	15756509	16	+	26472758	K562	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	0.4165997030491273	[354]	[399]	3	hSpCas9	negative selection	677791
15841640	15841663	CHR_HSCHR16_1_CTG1	+	26472758	K562	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000276480	0.4165997030491273	[354]	[399]	3	hSpCas9	negative selection	677792
15760640	15760663	16	+	26627737	DLD1	viability	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	1.7061086051813805	[336]	[283,458,299]	9	hSpCas9	negative selection	792763
15771581	15771604	16	-	26627737	DLD1	viability	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.2721974920534565	[650]	[299,271,176]	3	hSpCas9	negative selection	792764
15776130	15776153	16	-	26627737	DLD1	viability	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.2187390246291221	[1070]	[370,288,488]	2	hSpCas9	negative selection	792765
15786653	15786676	16	-	26627737	DLD1	viability	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-0.20739274110828942	[1077]	[293,379,216]	-2	hSpCas9	negative selection	792766
15823268	15823291	16	+	26627737	DLD1	viability	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	-0.44440979238544054	[799]	[248,235,83]	-4	hSpCas9	negative selection	792767
15837929	15837952	16	-	26627737	DLD1	viability	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	0.7316395353658289	[800]	[301,664,307]	7	hSpCas9	negative selection	792770
15760640	15760663	16	+	26627737	GBM cells	viability after 5 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.8237075306965117	[314]	[266,330]	9	hSpCas9	negative selection	875078
15771581	15771604	16	-	26627737	GBM cells	viability after 5 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.06823384589728557	[264]	[156,140]	1	hSpCas9	negative selection	875079
15776130	15776153	16	-	26627737	GBM cells	viability after 5 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.07451208474319237	[563]	[315,320]	1	hSpCas9	negative selection	875080
15786653	15786676	16	-	26627737	GBM cells	viability after 5 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-0.5627850631572845	[397]	[187,100]	-7	hSpCas9	negative selection	875081
15823268	15823291	16	+	26627737	GBM cells	viability after 5 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	-0.4819909394740125	[361]	[109,167]	-6	hSpCas9	negative selection	875082
15837929	15837952	16	-	26627737	GBM cells	viability after 5 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	-0.22574869839020506	[603]	[278,274]	-4	hSpCas9	negative selection	875085
15760640	15760663	16	+	26627737	GBM cells	viability after 13 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	1.0691386158640594	[314]	[394,328]	9	hSpCas9	negative selection	957393
15771581	15771604	16	-	26627737	GBM cells	viability after 13 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.09699307045862424	[264]	[177,98]	-1	hSpCas9	negative selection	957394
15776130	15776153	16	-	26627737	GBM cells	viability after 13 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.3629872461704844	[563]	[408,380]	4	hSpCas9	negative selection	957395
15786653	15786676	16	-	26627737	GBM cells	viability after 13 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-0.14235766559831842	[397]	[193,196]	-2	hSpCas9	negative selection	957396
15823268	15823291	16	+	26627737	GBM cells	viability after 13 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	-0.5519702660656844	[361]	[144,124]	-6	hSpCas9	negative selection	957397
15837929	15837952	16	-	26627737	GBM cells	viability after 13 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	-0.04021977879495631	[603]	[353,289]	0	hSpCas9	negative selection	957400
15760640	15760663	16	+	26627737	GBM cells	viability after 21 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.8732957809236458	[314]	[301,323]	8	hSpCas9	negative selection	1039708
15771581	15771604	16	-	26627737	GBM cells	viability after 21 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.30926669844855437	[264]	[180,175]	3	hSpCas9	negative selection	1039709
15776130	15776153	16	-	26627737	GBM cells	viability after 21 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.12711929856470539	[563]	[354,315]	1	hSpCas9	negative selection	1039710
15786653	15786676	16	-	26627737	GBM cells	viability after 21 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.08686675116719533	[397]	[237,221]	0	hSpCas9	negative selection	1039711
15823268	15823291	16	+	26627737	GBM cells	viability after 21 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	-0.8549621163641812	[361]	[114,102]	-6	hSpCas9	negative selection	1039712
15837929	15837952	16	-	26627737	GBM cells	viability after 21 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	0.2794597357071864	[603]	[379,414]	3	hSpCas9	negative selection	1039715
15760640	15760663	16	+	26627737	RPE1	viability after 9 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.8383606699901464	[1186]	[701,615]	5	hSpCas9	negative selection	1122023
15771581	15771604	16	-	26627737	RPE1	viability after 9 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.1719305879125952	[1592]	[350,560]	-1	hSpCas9	negative selection	1122024
15776130	15776153	16	-	26627737	RPE1	viability after 9 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	-1.0760747004360123	[3921]	[684,449]	-7	hSpCas9	negative selection	1122025
15786653	15786676	16	-	26627737	RPE1	viability after 9 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-1.4595463288698667	[1592]	[224,124]	-8	hSpCas9	negative selection	1122026
15823268	15823291	16	+	26627737	RPE1	viability after 9 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.5384015368671752	[575]	[181,364]	3	hSpCas9	negative selection	1122027
15837929	15837952	16	-	26627737	RPE1	viability after 9 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	1.7741532152001482	[576]	[640,587]	8	hSpCas9	negative selection	1122030
15760640	15760663	16	+	26627737	RPE1	viability after 12 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	1.2018570207389234	[1186]	[787,675]	7	hSpCas9	negative selection	1204338
15771581	15771604	16	-	26627737	RPE1	viability after 12 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.29773492453625194	[1592]	[324,738]	2	hSpCas9	negative selection	1204339
15776130	15776153	16	-	26627737	RPE1	viability after 12 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	-1.114500488528707	[3921]	[627,336]	-6	hSpCas9	negative selection	1204340
15786653	15786676	16	-	26627737	RPE1	viability after 12 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-1.5395052796441093	[1592]	[205,84]	-8	hSpCas9	negative selection	1204341
15823268	15823291	16	+	26627737	RPE1	viability after 12 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.7377331640588597	[575]	[259,255]	5	hSpCas9	negative selection	1204342
15837929	15837952	16	-	26627737	RPE1	viability after 12 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	1.7514319604610429	[576]	[536,505]	8	hSpCas9	negative selection	1204345
15760640	15760663	16	+	26627737	RPE1	viability after 15 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.796892234262082	[1186]	[562,602]	5	hSpCas9	negative selection	1286653
15771581	15771604	16	-	26627737	RPE1	viability after 15 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.10133384828884129	[1592]	[431,532]	0	hSpCas9	negative selection	1286654
15776130	15776153	16	-	26627737	RPE1	viability after 15 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	-0.9559076884513291	[3921]	[715,432]	-6	hSpCas9	negative selection	1286655
15786653	15786676	16	-	26627737	RPE1	viability after 15 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-1.7807649230174925	[1592]	[122,138]	-8	hSpCas9	negative selection	1286656
15823268	15823291	16	+	26627737	RPE1	viability after 15 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.7692377987832357	[575]	[237,315]	5	hSpCas9	negative selection	1286657
15837929	15837952	16	-	26627737	RPE1	viability after 15 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	1.4122407296282242	[576]	[579,293]	7	hSpCas9	negative selection	1286660
15760640	15760663	16	+	26627737	RPE1	viability after 18 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	1.2764856937237674	[1186]	[746,806]	7	hSpCas9	negative selection	1368968
15771581	15771604	16	-	26627737	RPE1	viability after 18 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.14167199752162551	[1592]	[336,445]	-1	hSpCas9	negative selection	1368969
15776130	15776153	16	-	26627737	RPE1	viability after 18 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	-1.2446762884439686	[3921]	[596,285]	-6	hSpCas9	negative selection	1368970
15786653	15786676	16	-	26627737	RPE1	viability after 18 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-0.34643677428653263	[1592]	[472,193]	-2	hSpCas9	negative selection	1368971
15823268	15823291	16	+	26627737	RPE1	viability after 18 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.7598056972008832	[575]	[210,318]	4	hSpCas9	negative selection	1368972
15837929	15837952	16	-	26627737	RPE1	viability after 18 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	1.4730617654646876	[576]	[556,298]	7	hSpCas9	negative selection	1368975
15760640	15760663	16	+	26627737	HeLa	viability after 8 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.294533647642939	[582]	[409,349,202]	2	hSpCas9	negative selection	1451283
15771581	15771604	16	-	26627737	HeLa	viability after 8 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.21306409421222278	[508]	[166,210,189]	-2	hSpCas9	negative selection	1451284
15776130	15776153	16	-	26627737	HeLa	viability after 8 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.16900746264684963	[1206]	[690,725,390]	1	hSpCas9	negative selection	1451285
15786653	15786676	16	-	26627737	HeLa	viability after 8 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-0.07698212510162239	[693]	[384,155,335]	0	hSpCas9	negative selection	1451286
15823268	15823291	16	+	26627737	HeLa	viability after 8 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	-0.10143321229175206	[661]	[388,188,254]	-1	hSpCas9	negative selection	1451287
15837929	15837952	16	-	26627737	HeLa	viability after 8 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	-0.2649521038579692	[1155]	[520,406,354]	-3	hSpCas9	negative selection	1451290
15760640	15760663	16	+	26627737	HeLa	viability after 12 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.2774428235087528	[582]	[382,260,237]	2	hSpCas9	negative selection	1533598
15771581	15771604	16	-	26627737	HeLa	viability after 12 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.4935782271428891	[508]	[256,289,340]	4	hSpCas9	negative selection	1533599
15776130	15776153	16	-	26627737	HeLa	viability after 12 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	-0.14834655784905082	[1206]	[399,560,375]	-1	hSpCas9	negative selection	1533600
15786653	15786676	16	-	26627737	HeLa	viability after 12 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.08811486193803808	[693]	[249,304,357]	0	hSpCas9	negative selection	1533601
15823268	15823291	16	+	26627737	HeLa	viability after 12 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.16681305966757454	[661]	[262,269,390]	1	hSpCas9	negative selection	1533602
15837929	15837952	16	-	26627737	HeLa	viability after 12 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	-0.28206852855783815	[1155]	[420,340,422]	-2	hSpCas9	negative selection	1533605
15760640	15760663	16	+	26627737	HeLa	viability after 15 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.8853545633275819	[582]	[433,325,564]	6	hSpCas9	negative selection	1615913
15771581	15771604	16	-	26627737	HeLa	viability after 15 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.4607438561014083	[508]	[62,212,178]	-4	hSpCas9	negative selection	1615914
15776130	15776153	16	-	26627737	HeLa	viability after 15 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.07188117519387038	[1206]	[560,529,452]	0	hSpCas9	negative selection	1615915
15786653	15786676	16	-	26627737	HeLa	viability after 15 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.05662476068065503	[693]	[204,258,428]	0	hSpCas9	negative selection	1615916
15823268	15823291	16	+	26627737	HeLa	viability after 15 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	-0.16774934034035616	[661]	[444,105,159]	-1	hSpCas9	negative selection	1615917
15837929	15837952	16	-	26627737	HeLa	viability after 15 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	-0.4930186861365673	[1155]	[261,432,306]	-4	hSpCas9	negative selection	1615920
15760640	15760663	16	+	26627737	HeLa	viability after 18 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.8979047715784916	[582]	[300,266,564]	6	hSpCas9	negative selection	1698228
15771581	15771604	16	-	26627737	HeLa	viability after 18 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.4236228239771834	[508]	[46,179,178]	-4	hSpCas9	negative selection	1698229
15776130	15776153	16	-	26627737	HeLa	viability after 18 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.0968017919034665	[1206]	[392,439,452]	0	hSpCas9	negative selection	1698230
15786653	15786676	16	-	26627737	HeLa	viability after 18 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.03650600489791633	[693]	[129,213,428]	0	hSpCas9	negative selection	1698231
15823268	15823291	16	+	26627737	HeLa	viability after 18 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	-0.18703574744441087	[661]	[292,86,159]	-1	hSpCas9	negative selection	1698232
15837929	15837952	16	-	26627737	HeLa	viability after 18 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	-0.4610400286116838	[1155]	[185,363,306]	-4	hSpCas9	negative selection	1698235
15760640	15760663	16	+	26627737	HCT116	viability after 6 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	-1.0029642579069187	[1548]	[281,32]	-5	hSpCas9	negative selection	1780543
15771581	15771604	16	-	26627737	HCT116	viability after 6 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	1.414556223695088	[767]	[404,275]	7	hSpCas9	negative selection	1780544
15776130	15776153	16	-	26627737	HCT116	viability after 6 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.714496200462162	[1589]	[511,353]	4	hSpCas9	negative selection	1780545
15786653	15786676	16	-	26627737	HCT116	viability after 6 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-0.5781408971563808	[1051]	[249,33]	-3	hSpCas9	negative selection	1780546
15823268	15823291	16	+	26627737	HCT116	viability after 6 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.20061972675917428	[1120]	[275,161]	1	hSpCas9	negative selection	1780547
15837929	15837952	16	-	26627737	HCT116	viability after 6 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	0.9575935310836383	[1564]	[850,271]	5	hSpCas9	negative selection	1780550
15760640	15760663	16	+	26627737	HCT116	viability after 8 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.6503748988087312	[284]	[225,257,254]	6	hSpCas9	negative selection	1862858
15771581	15771604	16	-	26627737	HCT116	viability after 8 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.6134454567087311	[513]	[173,180,199]	-6	hSpCas9	negative selection	1862859
15776130	15776153	16	-	26627737	HCT116	viability after 8 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.7277157051932827	[530]	[330,479,637]	7	hSpCas9	negative selection	1862860
15786653	15786676	16	-	26627737	HCT116	viability after 8 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.02717321012952023	[592]	[310,393,293]	0	hSpCas9	negative selection	1862861
15823268	15823291	16	+	26627737	HCT116	viability after 8 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.34232176698919603	[364]	[294,242,227]	3	hSpCas9	negative selection	1862862
15837929	15837952	16	-	26627737	HCT116	viability after 8 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	0.9388796332834013	[342]	[442,248,395]	8	hSpCas9	negative selection	1862865
15760640	15760663	16	+	26627737	HCT116	viability after 9 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.11019552555199241	[1548]	[446,445]	0	hSpCas9	negative selection	1945173
15771581	15771604	16	-	26627737	HCT116	viability after 9 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.8017722073402662	[767]	[452,281]	5	hSpCas9	negative selection	1945174
15776130	15776153	16	-	26627737	HCT116	viability after 9 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.8998635573827203	[1589]	[799,785]	6	hSpCas9	negative selection	1945175
15786653	15786676	16	-	26627737	HCT116	viability after 9 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.29108820820846826	[1051]	[212,446]	2	hSpCas9	negative selection	1945176
15823268	15823291	16	+	26627737	HCT116	viability after 9 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	-0.19991740268465796	[1120]	[397,151]	-1	hSpCas9	negative selection	1945177
15837929	15837952	16	-	26627737	HCT116	viability after 9 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	-0.8538021452659161	[1564]	[209,247]	-5	hSpCas9	negative selection	1945180
15760640	15760663	16	+	26627737	HCT116	viability after 12 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.9887655912104405	[284]	[228,351,317]	8	hSpCas9	negative selection	2027488
15771581	15771604	16	-	26627737	HCT116	viability after 12 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.029363466356732593	[513]	[283,291,216]	0	hSpCas9	negative selection	2027489
15776130	15776153	16	-	26627737	HCT116	viability after 12 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.5719617148896311	[530]	[435,347,456]	5	hSpCas9	negative selection	2027490
15786653	15786676	16	-	26627737	HCT116	viability after 12 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.1641989417072628	[592]	[331,302,412]	1	hSpCas9	negative selection	2027491
15823268	15823291	16	+	26627737	HCT116	viability after 12 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.6540342418900027	[364]	[275,310,320]	6	hSpCas9	negative selection	2027492
15837929	15837952	16	-	26627737	HCT116	viability after 12 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	1.055439826697327	[342]	[421,343,352]	8	hSpCas9	negative selection	2027495
15760640	15760663	16	+	26627737	HCT116	viability after 15 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.8852990525157987	[284]	[264,380,256]	7	hSpCas9	negative selection	2109803
15771581	15771604	16	-	26627737	HCT116	viability after 15 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.3396356090739332	[513]	[223,184,288]	-4	hSpCas9	negative selection	2109804
15776130	15776153	16	-	26627737	HCT116	viability after 15 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.803861932579922	[530]	[832,458,343]	7	hSpCas9	negative selection	2109805
15786653	15786676	16	-	26627737	HCT116	viability after 15 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-0.2001877029645398	[592]	[281,346,258]	-2	hSpCas9	negative selection	2109806
15823268	15823291	16	+	26627737	HCT116	viability after 15 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.3397783524266176	[364]	[374,234,199]	3	hSpCas9	negative selection	2109807
15837929	15837952	16	-	26627737	HCT116	viability after 15 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	0.8548461777880141	[342]	[586,165,343]	7	hSpCas9	negative selection	2109810
15760640	15760663	16	+	26627737	HCT116	viability after 18 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	1.0053994735259406	[284]	[199,254,380]	7	hSpCas9	negative selection	2192118
15771581	15771604	16	-	26627737	HCT116	viability after 18 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.6759651466477915	[513]	[227,130,106]	-6	hSpCas9	negative selection	2192119
15776130	15776153	16	-	26627737	HCT116	viability after 18 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.7250735287578941	[530]	[379,536,344]	6	hSpCas9	negative selection	2192120
15786653	15786676	16	-	26627737	HCT116	viability after 18 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.04956554809348901	[592]	[311,222,362]	0	hSpCas9	negative selection	2192121
15823268	15823291	16	+	26627737	HCT116	viability after 18 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.6756244069993116	[364]	[280,269,295]	5	hSpCas9	negative selection	2192122
15837929	15837952	16	-	26627737	HCT116	viability after 18 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	1.0747206387494508	[342]	[518,183,355]	8	hSpCas9	negative selection	2192125
15828534	15828557	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCCCAGCACTTCGGGTGG	MYH11	ENSG00000133392	-3.9690945324429574	[10,229]	[0,1]	-9	dCas9-VP64	positive selection	2383172
15913662	15913685	CHR_HSCHR16_1_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCCCAGCACTTCGGGTGG	MYH11	ENSG00000276480	-3.9690945324429574	[10,229]	[0,1]	-9	dCas9-VP64	positive selection	2383173
15811361	15811384	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGAAGGGAAGGGAAGGGAAAG	MYH11	ENSG00000276480	2.1815077648362022	[0,0]	[0,0]	7	dCas9-VP64	positive selection	2383893
15726207	15726230	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGAAGGGAAGGGAAGGGAAAG	MYH11	ENSG00000133392	2.1815077648362022	[0,0]	[0,0]	7	dCas9-VP64	positive selection	2383894
15921930	15921953	CHR_HSCHR16_1_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCTGCCTCCCGGG	MYH11	ENSG00000276480	-0.8346021834980462	[246,704]	[74,41]	-5	dCas9-VP64	positive selection	2386306
15836798	15836821	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCTGCCTCCCGGG	MYH11	ENSG00000133392	-0.8346021834980462	[246,704]	[74,41]	-5	dCas9-VP64	positive selection	2386307
15829579	15829602	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGAGGCGGGTGGATCACAAAG	MYH11	ENSG00000276480	2.1502832554388824	[230,177]	[276,116]	7	dCas9-VP64	positive selection	2400401
15744425	15744448	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGAGGCGGGTGGATCACAAAG	MYH11	ENSG00000133392	2.1502832554388824	[230,177]	[276,116]	7	dCas9-VP64	positive selection	2400402
15921941	15921964	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATTGCTTGAACCCGGGAGGCAG	MYH11	ENSG00000276480	0.3272337489211984	[8,246]	[5,67]	1	dCas9-VP64	positive selection	2421232
15836809	15836832	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATTGCTTGAACCCGGGAGGCAG	MYH11	ENSG00000133392	0.3272337489211984	[8,246]	[5,67]	1	dCas9-VP64	positive selection	2421233
15889287	15889310	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAAGAGAGAGAGAGAGAGAATGG	MYH11	ENSG00000276480	0.6316515901792452	[28,11]	[9,2]	2	dCas9-VP64	positive selection	2441208
15804163	15804186	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAAGAGAGAGAGAGAGAGAATGG	MYH11	ENSG00000133392	0.6316515901792452	[28,11]	[9,2]	2	dCas9-VP64	positive selection	2441209
15793092	15793115	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGACGGAGTCTCGCTCTGGAG	MYH11	ENSG00000276480	-0.9138531946650479	[176,89]	[14,14]	-5	dCas9-VP64	positive selection	2443882
15707938	15707961	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGACGGAGTCTCGCTCTGGAG	MYH11	ENSG00000133392	-0.9138531946650479	[176,89]	[14,14]	-5	dCas9-VP64	positive selection	2443884
15880473	15880496	CHR_HSCHR16_1_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCTGTAATCCCAGCACTTGGG	MYH11	ENSG00000276480	-1.262579619046977	[170,274]	[19,19]	-7	dCas9-VP64	positive selection	2446355
15795349	15795372	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCTGTAATCCCAGCACTTGGG	MYH11	ENSG00000133392	-1.262579619046977	[170,274]	[19,19]	-7	dCas9-VP64	positive selection	2446356
15708980	15709003	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCCAGGCTGGAGTGCAGGGG	MYH11	ENSG00000133392	-0.014347572194705283	[459,63]	[82,26]	0	dCas9-VP64	positive selection	2457909
15794134	15794157	CHR_HSCHR16_1_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCCAGGCTGGAGTGCAGGGG	MYH11	ENSG00000276480	-0.014347572194705283	[459,63]	[82,26]	0	dCas9-VP64	positive selection	2457910
15774796	15774819	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGTTTGAGACCAGCTCGG	MYH11	ENSG00000133392	0.362963240197711	[121,64]	[24,26]	1	dCas9-VP64	positive selection	2472617
15859949	15859972	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGTTTGAGACCAGCTCGG	MYH11	ENSG00000276480	0.362963240197711	[121,64]	[24,26]	1	dCas9-VP64	positive selection	2472618
15828534	15828557	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCCCAGCACTTCGGGTGG	MYH11	ENSG00000133392	-1.0802329755633977	[58,72]	[5,12]	-9	dCas9-VP64	positive selection	2478427
15913662	15913685	CHR_HSCHR16_1_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCCCAGCACTTCGGGTGG	MYH11	ENSG00000276480	-1.0802329755633977	[58,72]	[5,12]	-9	dCas9-VP64	positive selection	2478428
15811361	15811384	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGAAGGGAAGGGAAGGGAAAG	MYH11	ENSG00000276480	0.3564044471604775	[2,18]	[1,5]	3	dCas9-VP64	positive selection	2479148
15726207	15726230	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGAAGGGAAGGGAAGGGAAAG	MYH11	ENSG00000133392	0.3564044471604775	[2,18]	[1,5]	3	dCas9-VP64	positive selection	2479149
15921930	15921953	CHR_HSCHR16_1_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCTGCCTCCCGGG	MYH11	ENSG00000276480	0.6564409522361534	[325,125]	[135,99]	5	dCas9-VP64	positive selection	2481561
15836798	15836821	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCTGCCTCCCGGG	MYH11	ENSG00000133392	0.6564409522361534	[325,125]	[135,99]	5	dCas9-VP64	positive selection	2481562
15829579	15829602	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGAGGCGGGTGGATCACAAAG	MYH11	ENSG00000276480	0.9222606626235144	[35,66]	[18,42]	6	dCas9-VP64	positive selection	2495656
15744425	15744448	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGAGGCGGGTGGATCACAAAG	MYH11	ENSG00000133392	0.9222606626235144	[35,66]	[18,42]	6	dCas9-VP64	positive selection	2495657
15921941	15921964	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATTGCTTGAACCCGGGAGGCAG	MYH11	ENSG00000276480	0.646844560450541	[111,36]	[52,24]	5	dCas9-VP64	positive selection	2516487
15836809	15836832	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATTGCTTGAACCCGGGAGGCAG	MYH11	ENSG00000133392	0.646844560450541	[111,36]	[52,24]	5	dCas9-VP64	positive selection	2516488
15889287	15889310	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAAGAGAGAGAGAGAGAGAATGG	MYH11	ENSG00000276480	0.43533825533627796	[75,43]	[28,22]	3	dCas9-VP64	positive selection	2536463
15804163	15804186	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAAGAGAGAGAGAGAGAGAATGG	MYH11	ENSG00000133392	0.43533825533627796	[75,43]	[28,22]	3	dCas9-VP64	positive selection	2536464
15793092	15793115	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGACGGAGTCTCGCTCTGGAG	MYH11	ENSG00000276480	1.2938008933610645	[146,100]	[61,133]	7	dCas9-VP64	positive selection	2539137
15707938	15707961	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGACGGAGTCTCGCTCTGGAG	MYH11	ENSG00000133392	1.2938008933610645	[146,100]	[61,133]	7	dCas9-VP64	positive selection	2539139
15880473	15880496	CHR_HSCHR16_1_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCTGTAATCCCAGCACTTGGG	MYH11	ENSG00000276480	0.31922581039074327	[700,765]	[259,334]	2	dCas9-VP64	positive selection	2541610
15795349	15795372	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCTGTAATCCCAGCACTTGGG	MYH11	ENSG00000133392	0.31922581039074327	[700,765]	[259,334]	2	dCas9-VP64	positive selection	2541611
15708980	15709003	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCCAGGCTGGAGTGCAGGGG	MYH11	ENSG00000133392	-0.8839666549432982	[334,175]	[40,48]	-8	dCas9-VP64	positive selection	2553164
15794134	15794157	CHR_HSCHR16_1_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCCAGGCTGGAGTGCAGGGG	MYH11	ENSG00000276480	-0.8839666549432982	[334,175]	[40,48]	-8	dCas9-VP64	positive selection	2553165
15774796	15774819	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGTTTGAGACCAGCTCGG	MYH11	ENSG00000133392	-1.016658803330618	[35,140]	[14,11]	-8	dCas9-VP64	positive selection	2567872
15859949	15859972	CHR_HSCHR16_1_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGTTTGAGACCAGCTCGG	MYH11	ENSG00000276480	-1.016658803330618	[35,140]	[14,11]	-8	dCas9-VP64	positive selection	2567873
15823326	15823349	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGATCGTCGACATGTACAAGGG	MYH11	ENSG00000133392	-0.693041710546656	[3,3]	[1,1]	-8	hSpCas9	positive selection	3004136
15756488	15756511	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGGCCAGCACACCTGGAGGG	MYH11	ENSG00000133392	0.10340183221650151	[2,2]	[2,1]	2	hSpCas9	positive selection	3004137
15760572	15760595	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTCGCCCAACCTTGATACGAGG	MYH11	ENSG00000133392	-0.16163168614198442	[0,0]	[0,0]	-2	hSpCas9	positive selection	3004138
15747927	15747950	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTCAAGCTACGAGATCCTGGCGG	MYH11	ENSG00000133392	0.3290663810852588	[4,4]	[5,4]	7	hSpCas9	positive selection	3004139
15823326	15823349	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGATCGTCGACATGTACAAGGG	MYH11	ENSG00000133392	-0.701268638770195	[3,3]	[2,0]	-8	hSpCas9	positive selection	3071994
15756488	15756511	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGGCCAGCACACCTGGAGGG	MYH11	ENSG00000133392	-0.5310787900580943	[2,2]	[1,0]	-7	hSpCas9	positive selection	3071995
15760572	15760595	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTCGCCCAACCTTGATACGAGG	MYH11	ENSG00000133392	0.26350043321408534	[0,0]	[0,0]	4	hSpCas9	positive selection	3071996
15747927	15747950	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTCAAGCTACGAGATCCTGGCGG	MYH11	ENSG00000133392	-0.3268132084013964	[4,4]	[3,1]	-5	hSpCas9	positive selection	3071997
15837919	15837942		+	24336571	A375	resistance to PLX after 7 days	CTGAGAAGTACCGCTCCCTCAGG	MYH11	ENSG00000133392	0.016472245623083914	[64,63]	[60,67]	0	hSpCas9	positive selection	3129211
15724944	15724967		-	24336571	A375	resistance to PLX after 7 days	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.06580306349053977	[29,30]	[29,27]	-2	hSpCas9	positive selection	3129212
15838142	15838165		-	24336571	A375	resistance to PLX after 7 days	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	-0.2871643799322197	[18,20]	[16,14]	-8	hSpCas9	positive selection	3129213
15837919	15837942		+	24336571	A375	resistance to PLX after 14 days	CTGAGAAGTACCGCTCCCTCAGG	MYH11	ENSG00000133392	0.05227255757628235	[67,64]	[30,32]	0	hSpCas9	positive selection	3187004
15724944	15724967		-	24336571	A375	resistance to PLX after 14 days	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.13524367947728066	[29,26]	[15,12]	1	hSpCas9	positive selection	3187005
15838142	15838165		-	24336571	A375	resistance to PLX after 14 days	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.16920858322692467	[15,19]	[6,11]	1	hSpCas9	positive selection	3187006
15837919	15837942		+	24336571	A375	viability after 7 days	CTGAGAAGTACCGCTCCCTCAGG	MYH11	ENSG00000133392	0.20159873413921225	[58]	[64,63]	3	hSpCas9	negative selection	3244797
15724944	15724967		-	24336571	A375	viability after 7 days	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.10084328433363199	[33]	[29,30]	-1	hSpCas9	negative selection	3244798
15838142	15838165		-	24336571	A375	viability after 7 days	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.025124967733003545	[19]	[18,20]	0	hSpCas9	negative selection	3244799
15837919	15837942		+	24336571	A375	viability after 14 days	CTGAGAAGTACCGCTCCCTCAGG	MYH11	ENSG00000133392	0.2723831953342155	[58]	[67,64]	3	hSpCas9	negative selection	3302590
15724944	15724967		-	24336571	A375	viability after 14 days	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.16709157956765908	[33]	[29,26]	-2	hSpCas9	negative selection	3302591
15838142	15838165		-	24336571	A375	viability after 14 days	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	-0.08539937558730992	[19]	[15,19]	-1	hSpCas9	negative selection	3302592
15724970	15724993	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	2.9535454632687324	[157,157]	[7,7]	8	hSpCas9	positive selection	3380611
15838216	15838239	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.5818775766511088	[228,228]	[0,0]	-4	hSpCas9	positive selection	3380612
15724944	15724967	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.4244361972810935	[113,113]	[0,0]	2	hSpCas9	positive selection	3380613
15823326	15823349	16	-	26780180	HT29	viability (Avana library 4 designs)	AAGATCGTCGACATGTACAAGGG	MYH11	ENSG00000133392	2.53446327332891	[]	[]	8	hSpCas9	negative selection	3441942
15756487	15756510	16	+	26780180	HT29	viability (Avana library 4 designs)	GCAGGGCCAGCACACCTGGAGGG	MYH11	ENSG00000133392	1.59459293552925	[]	[]	6	hSpCas9	negative selection	3441943
15760571	15760594	16	+	26780180	HT29	viability (Avana library 4 designs)	TCTCGCCCAACCTTGATACGAGG	MYH11	ENSG00000133392	0.832963019394412	[]	[]	3	hSpCas9	negative selection	3441944
15747927	15747950	16	-	26780180	HT29	viability (Avana library 4 designs)	TTCAAGCTACGAGATCCTGGCGG	MYH11	ENSG00000133392	0.553627970829108	[]	[]	2	hSpCas9	negative selection	3441945
15823326	15823349	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAGATCGTCGACATGTACAAGGG	MYH11	ENSG00000133392	-3.04267650647166	[]	[]	-4	hSpCas9	negative selection	3532900
15760571	15760594	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCGCCCAACCTTGATACGAGG	MYH11	ENSG00000133392	-0.876158192886703	[]	[]	-1	hSpCas9	negative selection	3532901
15747927	15747950	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCAAGCTACGAGATCCTGGCGG	MYH11	ENSG00000133392	-1.70818015409617	[]	[]	-2	hSpCas9	negative selection	3532902
15756487	15756510	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGGCCAGCACACCTGGAGGG	MYH11	ENSG00000133392	-1.02263902257044	[]	[]	-1	hSpCas9	negative selection	3532903
15741811	15741834	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	AACTGCAGAAGACCAAGGAGCGG	MYH11	ENSG00000133392	1.27521145002206	[]	[]	1	hSpCas9	negative selection	3532904
15823284	15823307	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGATGGCGTAGATGTGAGGCGG	MYH11	ENSG00000133392	4.46273291798821	[]	[]	7	hSpCas9	negative selection	3532905
15823326	15823349	16	-	26780180	A375	viability (Avana lentiGuide)	AAGATCGTCGACATGTACAAGGG	MYH11	ENSG00000133392	8.52821672194479	[]	[]	6	hSpCas9	negative selection	3641559
15760571	15760594	16	+	26780180	A375	viability (Avana lentiGuide)	TCTCGCCCAACCTTGATACGAGG	MYH11	ENSG00000133392	5.71805202230588	[]	[]	5	hSpCas9	negative selection	3641560
15747927	15747950	16	-	26780180	A375	viability (Avana lentiGuide)	TTCAAGCTACGAGATCCTGGCGG	MYH11	ENSG00000133392	0.855818078205566	[]	[]	1	hSpCas9	negative selection	3641561
15756487	15756510	16	+	26780180	A375	viability (Avana lentiGuide)	GCAGGGCCAGCACACCTGGAGGG	MYH11	ENSG00000133392	9.73725997761813	[]	[]	6	hSpCas9	negative selection	3641562
15741811	15741834	16	-	26780180	A375	viability (Avana lentiGuide)	AACTGCAGAAGACCAAGGAGCGG	MYH11	ENSG00000133392	-1.59120300220448	[]	[]	-3	hSpCas9	negative selection	3641563
15823284	15823307	16	+	26780180	A375	viability (Avana lentiGuide)	GCGATGGCGTAGATGTGAGGCGG	MYH11	ENSG00000133392	1.05516887047014	[]	[]	1	hSpCas9	negative selection	3641564
15823326	15823349	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGATCGTCGACATGTACAAGGG	MYH11	ENSG00000133392	-0.507222373363937	[6]	[5,3]	-6	hSpCas9	positive selection	3750218
15760571	15760594	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCGCCCAACCTTGATACGAGG	MYH11	ENSG00000133392	-0.24260447143864594	[0]	[0,0]	-4	hSpCas9	positive selection	3750219
15747927	15747950	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCAAGCTACGAGATCCTGGCGG	MYH11	ENSG00000133392	-0.4570306993662223	[5]	[2,4]	-6	hSpCas9	positive selection	3750220
15756487	15756510	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGGCCAGCACACCTGGAGGG	MYH11	ENSG00000133392	-0.6257176793013554	[3]	[2,1]	-7	hSpCas9	positive selection	3750221
15741811	15741834	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACTGCAGAAGACCAAGGAGCGG	MYH11	ENSG00000133392	0.3720138061891591	[5]	[5,7]	9	hSpCas9	positive selection	3750222
15823284	15823307	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGATGGCGTAGATGTGAGGCGG	MYH11	ENSG00000133392	0.19161065073278366	[5]	[6,5]	5	hSpCas9	positive selection	3750223
15823326	15823349	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGATCGTCGACATGTACAAGGG	MYH11	ENSG00000133392	0.056176678414236035	[5]	[4,4]	1	hSpCas9	positive selection	3858825
15760571	15760594	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCGCCCAACCTTGATACGAGG	MYH11	ENSG00000133392	-0.9836835823272654	[1]	[0,0]	-8	hSpCas9	positive selection	3858826
15747927	15747950	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCAAGCTACGAGATCCTGGCGG	MYH11	ENSG00000133392	0.010416047999526279	[6]	[7,3]	0	hSpCas9	positive selection	3858827
15756487	15756510	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGGCCAGCACACCTGGAGGG	MYH11	ENSG00000133392	0.1923629325100355	[4]	[3,4]	5	hSpCas9	positive selection	3858828
15741811	15741834	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACTGCAGAAGACCAAGGAGCGG	MYH11	ENSG00000133392	0.20914326970121302	[6]	[5,6]	5	hSpCas9	positive selection	3858829
15823284	15823307	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGATGGCGTAGATGTGAGGCGG	MYH11	ENSG00000133392	0.17139137714330666	[7]	[6,7]	4	hSpCas9	positive selection	3858830
15724970	15724993	16	-	26780180	A375	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	1.67039820050402	[]	[]	9	hSpCas9	negative selection	3970143
15838216	15838239	16	+	26780180	A375	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	1.17891496001112	[]	[]	6	hSpCas9	negative selection	3970144
15724187	15724210	16	-	26780180	A375	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	1.27796710326453	[]	[]	7	hSpCas9	negative selection	3970145
15724944	15724967	16	-	26780180	A375	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	1.24747144293692	[]	[]	6	hSpCas9	negative selection	3970146
15724217	15724240	16	-	26780180	A375	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.5186734112162	[]	[]	1	hSpCas9	negative selection	3970147
15838142	15838165	16	-	26780180	A375	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.492022586008605	[]	[]	1	hSpCas9	negative selection	3970148
15724970	15724993	16	-	26780180	HT29	viability (GeCKOv2 library)	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	1.40380972378465	[]	[]	7	hSpCas9	negative selection	4078109
15838216	15838239	16	+	26780180	HT29	viability (GeCKOv2 library)	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	1.11317698756686	[]	[]	5	hSpCas9	negative selection	4078110
15724187	15724210	16	-	26780180	HT29	viability (GeCKOv2 library)	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	1.44483958298555	[]	[]	7	hSpCas9	negative selection	4078111
15724944	15724967	16	-	26780180	HT29	viability (GeCKOv2 library)	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	1.52593751515337	[]	[]	7	hSpCas9	negative selection	4078112
15724217	15724240	16	-	26780180	HT29	viability (GeCKOv2 library)	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.111306555308886	[]	[]	0	hSpCas9	negative selection	4078113
15838142	15838165	16	-	26780180	HT29	viability (GeCKOv2 library)	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	1.02628304196272	[]	[]	5	hSpCas9	negative selection	4078114
15837919	15837942	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGAGAAGTACCGCTCCCTCAGG	MYH11	ENSG00000133392	0.16565558342449482	[6]	[4,4]	4	hSpCas9	positive selection	4153759
15724944	15724967	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.1696465317771344	[5]	[3,3]	4	hSpCas9	positive selection	4153760
15838142	15838165	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.04792778081583088	[4]	[3,3]	1	hSpCas9	positive selection	4153761
15837919	15837942	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGAGAAGTACCGCTCCCTCAGG	MYH11	ENSG00000133392	0.71479018909382	[5]	[5,4,2,3]	4	hSpCas9	positive selection	4217781
15724944	15724967	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.8540260554509597	[4]	[4,2,2,3]	5	hSpCas9	positive selection	4217782
15838142	15838165	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.047666672555722184	[4]	[1,2,3,0]	0	hSpCas9	positive selection	4217783
15838142	15838165	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	-0.5235946968511711	[0]	[0,0]	-8	hSpCas9	positive selection	4284365
15724187	15724210	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	-0.41475146049292194	[3]	[2,0]	-7	hSpCas9	positive selection	4284366
15724217	15724240	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.34420670074583837	[1]	[1,0]	7	hSpCas9	positive selection	4284367
15724970	15724993	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.3804750147081152	[3]	[2,0]	-7	hSpCas9	positive selection	4348623
15838216	15838239	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.01511845740775257	[2]	[3,1]	0	hSpCas9	positive selection	4348624
15724944	15724967	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.26204595718153695	[2]	[2,1]	5	hSpCas9	positive selection	4348625
15753408	15753430	16	+	27760321	OCIAML3	viability	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	-0.1712361422619017	[618,576]	[408,423]	-2	hSpCas9	negative selection	4420485
15753485	15753507	16	-	27760321	OCIAML3	viability	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	0.07462349533798662	[667,547]	[437,576]	0	hSpCas9	negative selection	4420486
15771581	15771603	16	-	27760321	OCIAML3	viability	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.02820126377516141	[804,637]	[466,657]	0	hSpCas9	negative selection	4420487
15778798	15778820	16	-	27760321	OCIAML3	viability	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	0.5060240293502255	[320,221]	[284,314]	6	hSpCas9	negative selection	4420488
15823327	15823349	16	-	27760321	OCIAML3	viability	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	0.12066177058047167	[321,267]	[165,358]	1	hSpCas9	negative selection	4420489
15753408	15753430	16	+	27760321	OCIAML2	viability	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	-0.7082011331159452	[618,576]	[284,310]	-6	hSpCas9	negative selection	4503948
15753485	15753507	16	-	27760321	OCIAML2	viability	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	0.22335068597657248	[667,547]	[548,600]	3	hSpCas9	negative selection	4503949
15771581	15771603	16	-	27760321	OCIAML2	viability	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.1788602879944644	[804,637]	[527,825]	2	hSpCas9	negative selection	4503950
15778798	15778820	16	-	27760321	OCIAML2	viability	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	0.3933003054879928	[320,221]	[291,275]	5	hSpCas9	negative selection	4503951
15823327	15823349	16	-	27760321	OCIAML2	viability	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	0.15656831472808774	[321,267]	[282,240]	2	hSpCas9	negative selection	4503952
15753408	15753430	16	+	27760321	MV411	viability	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	-1.1110467999485132	[618,576]	[141,243]	-6	hSpCas9	negative selection	4587411
15753485	15753507	16	-	27760321	MV411	viability	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	0.7233342596633334	[667,547]	[683,621]	5	hSpCas9	negative selection	4587412
15771581	15771603	16	-	27760321	MV411	viability	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.11097910532541544	[804,637]	[348,571]	-1	hSpCas9	negative selection	4587413
15778798	15778820	16	-	27760321	MV411	viability	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	-0.999692997308618	[320,221]	[32,171]	-6	hSpCas9	negative selection	4587414
15823327	15823349	16	-	27760321	MV411	viability	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	-0.11783924525383516	[321,267]	[230,99]	-1	hSpCas9	negative selection	4587415
15753408	15753430	16	+	27760321	HL60	viability	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	-0.5953089105744851	[618,576]	[371,271]	-6	hSpCas9	negative selection	4670874
15753485	15753507	16	-	27760321	HL60	viability	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	0.019453209791905735	[667,547]	[549,448]	0	hSpCas9	negative selection	4670875
15771581	15771603	16	-	27760321	HL60	viability	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.19082715020738483	[804,637]	[669,666]	2	hSpCas9	negative selection	4670876
15778798	15778820	16	-	27760321	HL60	viability	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	0.18734484115790584	[320,221]	[268,228]	2	hSpCas9	negative selection	4670877
15823327	15823349	16	-	27760321	HL60	viability	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	0.5929304507348795	[321,267]	[425,293]	7	hSpCas9	negative selection	4670878
15753408	15753430	16	+	27760321	HT1080	viability	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	1.0757420064588468	[576,449]	[560,288]	6	hSpCas9	negative selection	4754337
15753485	15753507	16	-	27760321	HT1080	viability	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	0.828560777176159	[547,427]	[276,419]	4	hSpCas9	negative selection	4754338
15771581	15771603	16	-	27760321	HT1080	viability	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.9481668595098605	[637,497]	[353,526]	5	hSpCas9	negative selection	4754339
15778798	15778820	16	-	27760321	HT1080	viability	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	1.3685451398153625	[221,172]	[342,49]	7	hSpCas9	negative selection	4754340
15823327	15823349	16	-	27760321	HT1080	viability	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	-0.8707757964759475	[267,208]	[50,52]	-4	hSpCas9	negative selection	4754341
15753408	15753430	16	+	27760321	HT29	viability after 7 days	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	0.23113885317313254	[576,449]	[679,694,929]	3	hSpCas9	negative selection	4837800
15753485	15753507	16	-	27760321	HT29	viability after 7 days	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	-0.2136290954988101	[547,427]	[556,533,533]	-3	hSpCas9	negative selection	4837801
15771581	15771603	16	-	27760321	HT29	viability after 7 days	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.4759005367659366	[637,497]	[800,881,1321]	7	hSpCas9	negative selection	4837802
15778798	15778820	16	-	27760321	HT29	viability after 7 days	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	0.36446989895789556	[221,172]	[396,292,300]	5	hSpCas9	negative selection	4837803
15823327	15823349	16	-	27760321	HT29	viability after 7 days	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	-0.1879838470176698	[267,208]	[279,333,196]	-3	hSpCas9	negative selection	4837804
15753408	15753430	16	+	27760321	HT29	viability after 25 days	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	0.2970121088732015	[576,449]	[600,901,659]	3	hSpCas9	negative selection	4921263
15753485	15753507	16	-	27760321	HT29	viability after 25 days	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	-0.15571065378764187	[547,427]	[436,448,632]	-2	hSpCas9	negative selection	4921264
15771581	15771603	16	-	27760321	HT29	viability after 25 days	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.640995740844909	[637,497]	[823,1090,1145]	7	hSpCas9	negative selection	4921265
15778798	15778820	16	-	27760321	HT29	viability after 25 days	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	0.4619373100487751	[221,172]	[274,230,441]	5	hSpCas9	negative selection	4921266
15823327	15823349	16	-	27760321	HT29	viability after 25 days	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	-0.28180565296093407	[267,208]	[180,208,291]	-3	hSpCas9	negative selection	4921267
15753408	15753430	16	+	27760321	HT29	viability after 22 days	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	0.2429031247234863	[576,449]	[645,745,716]	2	hSpCas9	negative selection	5004726
15753485	15753507	16	-	27760321	HT29	viability after 22 days	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	0.11832160961626959	[547,427]	[590,607,638]	1	hSpCas9	negative selection	5004727
15771581	15771603	16	-	27760321	HT29	viability after 22 days	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.6699591992951244	[637,497]	[791,1198,1150]	7	hSpCas9	negative selection	5004728
15778798	15778820	16	-	27760321	HT29	viability after 22 days	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	0.7383632686918258	[221,172]	[429,356,353]	8	hSpCas9	negative selection	5004729
15823327	15823349	16	-	27760321	HT29	viability after 22 days	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	-0.0034827449720084003	[267,208]	[234,335,254]	0	hSpCas9	negative selection	5004730
15753408	15753430	16	+	27760321	HT29	viability after 19 days	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	0.06166903409462199	[576,449]	[595,747,496]	0	hSpCas9	negative selection	5088189
15753485	15753507	16	-	27760321	HT29	viability after 19 days	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	-0.7756755451560491	[547,427]	[512,227,258]	-6	hSpCas9	negative selection	5088190
15771581	15771603	16	-	27760321	HT29	viability after 19 days	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.09716332621786916	[637,497]	[694,850,543]	0	hSpCas9	negative selection	5088191
15778798	15778820	16	-	27760321	HT29	viability after 19 days	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	0.44172752632072365	[221,172]	[381,293,253]	4	hSpCas9	negative selection	5088192
15823327	15823349	16	-	27760321	HT29	viability after 19 days	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	-0.16661409971764585	[267,208]	[422,89,234]	-1	hSpCas9	negative selection	5088193
15753408	15753430	16	+	27760321	HT29	viability after 16 days	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	0.2922267478394215	[576,449]	[636,588,880]	3	hSpCas9	negative selection	5171652
15753485	15753507	16	-	27760321	HT29	viability after 16 days	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	0.2240906448806762	[547,427]	[502,538,860]	2	hSpCas9	negative selection	5171653
15771581	15771603	16	-	27760321	HT29	viability after 16 days	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.12726284141156596	[637,497]	[496,867,693]	1	hSpCas9	negative selection	5171654
15778798	15778820	16	-	27760321	HT29	viability after 16 days	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	0.28002927596017513	[221,172]	[335,274,199]	3	hSpCas9	negative selection	5171655
15823327	15823349	16	-	27760321	HT29	viability after 16 days	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	0.007838134330616864	[267,208]	[295,321,187]	0	hSpCas9	negative selection	5171656
15753408	15753430	16	+	27760321	HT29	viability after 13 days	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	0.11852009097794558	[576,449]	[620,603,710]	1	hSpCas9	negative selection	5255115
15753485	15753507	16	-	27760321	HT29	viability after 13 days	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	-0.047931983125101385	[547,427]	[615,432,590]	0	hSpCas9	negative selection	5255116
15771581	15771603	16	-	27760321	HT29	viability after 13 days	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.13558092723839377	[637,497]	[376,946,840]	1	hSpCas9	negative selection	5255117
15778798	15778820	16	-	27760321	HT29	viability after 13 days	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	0.38118572635268827	[221,172]	[238,370,285]	5	hSpCas9	negative selection	5255118
15823327	15823349	16	-	27760321	HT29	viability after 13 days	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	0.16460860000744704	[267,208]	[529,178,225]	2	hSpCas9	negative selection	5255119
15753408	15753430	16	+	27760321	HT29	viability after 10 days	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	0.11265359775416539	[576,449]	[438,858,783]	1	hSpCas9	negative selection	5338578
15753485	15753507	16	-	27760321	HT29	viability after 10 days	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	0.12016604956438859	[547,427]	[776,497,705]	1	hSpCas9	negative selection	5338579
15771581	15771603	16	-	27760321	HT29	viability after 10 days	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.2775604595661558	[637,497]	[1123,665,784]	4	hSpCas9	negative selection	5338580
15778798	15778820	16	-	27760321	HT29	viability after 10 days	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	0.3299975636133663	[221,172]	[319,189,413]	4	hSpCas9	negative selection	5338581
15823327	15823349	16	-	27760321	HT29	viability after 10 days	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	-0.13518286520876632	[267,208]	[137,483,198]	-2	hSpCas9	negative selection	5338582
15753408	15753430	16	+	27760321	MOLM13	viability	TCGGCCACAAACTTGTCGGAGG	MYH11	ENSG00000133392	-0.8265673357595036	[618,576]	[259,130]	-5	hSpCas9	negative selection	5422041
15753485	15753507	16	-	27760321	MOLM13	viability	GGACTATAATGCGAGTGCCTGG	MYH11	ENSG00000133392	0.7253416540810338	[667,547]	[706,442]	5	hSpCas9	negative selection	5422042
15771581	15771603	16	-	27760321	MOLM13	viability	GCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.752275366977404	[804,637]	[816,565]	5	hSpCas9	negative selection	5422043
15778798	15778820	16	-	27760321	MOLM13	viability	GACGTCACGGGTTACATCGTGG	MYH11	ENSG00000133392	0.10719446028428925	[320,221]	[141,180]	0	hSpCas9	negative selection	5422044
15823327	15823349	16	-	27760321	MOLM13	viability	AAGATCGTCGACATGTACAAGG	MYH11	ENSG00000133392	1.0101497520715936	[321,267]	[443,239]	7	hSpCas9	negative selection	5422045
15838142	15838165	16	-	27260156	BXPC3	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.3151927987684835	[63]	[39,86,108,103]	7	hSpCas9	negative selection	5556825
15724187	15724210	16	-	27260156	BXPC3	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.02655266350508806	[580]	[555,581,663,686]	0	hSpCas9	negative selection	5556826
15724217	15724240	16	-	27260156	BXPC3	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.19247786238463105	[68]	[80,89,64,93]	4	hSpCas9	negative selection	5556827
15724970	15724993	16	-	27260156	BXPC3	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.18903501476645032	[626]	[599,516,583,598]	-4	hSpCas9	negative selection	5621083
15838216	15838239	16	+	27260156	BXPC3	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.17046361437435525	[431]	[375,384,469,372]	-4	hSpCas9	negative selection	5621084
15724944	15724967	16	-	27260156	BXPC3	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.1566183545673493	[250]	[212,295,335,337]	3	hSpCas9	negative selection	5621085
15838142	15838165	16	-	27260156	A673	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.3411721268962906	[63]	[101,65,143,76]	7	hSpCas9	negative selection	5678076
15724187	15724210	16	-	27260156	A673	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.062317683685894076	[580]	[756,721,720,714]	1	hSpCas9	negative selection	5678077
15724217	15724240	16	-	27260156	A673	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.35972164573095844	[68]	[82,134,77,126]	8	hSpCas9	negative selection	5678078
15724970	15724993	16	-	27260156	A673	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.23236451584068946	[626]	[729,493,734,614]	-5	hSpCas9	negative selection	5742334
15838216	15838239	16	+	27260156	A673	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.13715304892945754	[431]	[448,523,612,687]	3	hSpCas9	negative selection	5742335
15724944	15724967	16	-	27260156	A673	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.0013013800409236165	[250]	[354,223,357,272]	0	hSpCas9	negative selection	5742336
15838142	15838165	16	-	27260156	A375	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.9359696278558094	[63]	[163,196,82,135]	9	hSpCas9	negative selection	5799327
15724187	15724210	16	-	27260156	A375	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	-0.11775475211496428	[580]	[752,476,563,678]	-2	hSpCas9	negative selection	5799328
15724217	15724240	16	-	27260156	A375	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.8652370527235913	[68]	[118,275,67,141]	9	hSpCas9	negative selection	5799329
15724970	15724993	16	-	27260156	A375	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.8835603937792187	[626]	[351,674,407,211]	-8	hSpCas9	negative selection	5863585
15838216	15838239	16	+	27260156	A375	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.035791114587401016	[431]	[419,713,639,340]	0	hSpCas9	negative selection	5863586
15724944	15724967	16	-	27260156	A375	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.19279410162797106	[250]	[362,449,269,278]	2	hSpCas9	negative selection	5863587
15838142	15838165	16	-	27260156	COLO741	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.5588730320929005	[63]	[124,150,87]	9	hSpCas9	negative selection	5920578
15724187	15724210	16	-	27260156	COLO741	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.2047927863615897	[580]	[896,937,741]	4	hSpCas9	negative selection	5920579
15724217	15724240	16	-	27260156	COLO741	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.5785591165674271	[68]	[56,164,163]	9	hSpCas9	negative selection	5920580
15724970	15724993	16	-	27260156	COLO741	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.42904145954550216	[626]	[692,616,489]	-7	hSpCas9	negative selection	5984836
15838216	15838239	16	+	27260156	COLO741	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.033860365233542314	[431]	[614,390,610]	0	hSpCas9	negative selection	5984837
15724944	15724967	16	-	27260156	COLO741	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.007475591655013991	[250]	[373,292,304]	0	hSpCas9	negative selection	5984838
15838142	15838165	16	-	27260156	CAL120	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	1.1862865061163708	[63]	[71,262,191]	9	hSpCas9	negative selection	6041829
15724187	15724210	16	-	27260156	CAL120	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.12645629958399396	[580]	[611,845,880]	2	hSpCas9	negative selection	6041830
15724217	15724240	16	-	27260156	CAL120	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.26542716331530425	[68]	[40,87,169]	4	hSpCas9	negative selection	6041831
15724970	15724993	16	-	27260156	CAL120	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.6732797306100078	[626]	[391,461,596]	-7	hSpCas9	negative selection	6106087
15838216	15838239	16	+	27260156	CAL120	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.3927771644629609	[431]	[293,461,453]	-5	hSpCas9	negative selection	6106088
15724944	15724967	16	-	27260156	CAL120	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.04647420673064695	[250]	[390,253,275]	0	hSpCas9	negative selection	6106089
15838142	15838165	16	-	27260156	CADOES1	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	-0.3335710868041679	[63]	[44,39,54,48]	-5	hSpCas9	negative selection	6163080
15724187	15724210	16	-	27260156	CADOES1	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.08538043912905852	[580]	[567,791,404,526]	1	hSpCas9	negative selection	6163081
15724217	15724240	16	-	27260156	CADOES1	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.6248342830331208	[68]	[159,141,14,77]	8	hSpCas9	negative selection	6163082
15724970	15724993	16	-	27260156	CADOES1	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.08157681338033768	[626]	[604,587,569,436]	-1	hSpCas9	negative selection	6227338
15838216	15838239	16	+	27260156	CADOES1	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.08036679267636204	[431]	[489,388,419,398]	1	hSpCas9	negative selection	6227339
15724944	15724967	16	-	27260156	CADOES1	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.19452276826815929	[250]	[295,249,266,254]	3	hSpCas9	negative selection	6227340
15838142	15838165	16	-	27260156	EWS502	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.6929142181534069	[63]	[135,65,103,131]	9	hSpCas9	negative selection	6284331
15724187	15724210	16	-	27260156	EWS502	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.2020255610634366	[580]	[698,692,630,813]	3	hSpCas9	negative selection	6284332
15724217	15724240	16	-	27260156	EWS502	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.8003214741446159	[68]	[153,81,102,170]	9	hSpCas9	negative selection	6284333
15724970	15724993	16	-	27260156	EWS502	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.19133346801986142	[626]	[271,646,621,836]	-3	hSpCas9	negative selection	6348589
15838216	15838239	16	+	27260156	EWS502	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.06585186568597831	[431]	[504,500,440,460]	1	hSpCas9	negative selection	6348590
15724944	15724967	16	-	27260156	EWS502	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.20677737303819688	[250]	[223,438,213,355]	3	hSpCas9	negative selection	6348591
15838142	15838165	16	-	27260156	EW8	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.6261181310975767	[63]	[125,79,68,51]	9	hSpCas9	negative selection	6405582
15724187	15724210	16	-	27260156	EW8	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.3160083618518684	[580]	[518,562,574,679]	6	hSpCas9	negative selection	6405583
15724217	15724240	16	-	27260156	EW8	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.5217240750352943	[68]	[46,121,70,78]	8	hSpCas9	negative selection	6405584
15724970	15724993	16	-	27260156	EW8	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.30506176903776944	[626]	[493,304,329,536]	-5	hSpCas9	negative selection	6469840
15838216	15838239	16	+	27260156	EW8	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.009942764140541585	[431]	[259,456,270,424]	0	hSpCas9	negative selection	6469841
15724944	15724967	16	-	27260156	EW8	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.11847793847512855	[250]	[221,230,213,216]	2	hSpCas9	negative selection	6469842
15838142	15838165	16	-	27260156	CORL105	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.3332006176315274	[63]	[87,84,97,106]	6	hSpCas9	negative selection	6526833
15724187	15724210	16	-	27260156	CORL105	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	-0.12011262610398024	[580]	[597,688,562,640]	-2	hSpCas9	negative selection	6526834
15724217	15724240	16	-	27260156	CORL105	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.32647965863526496	[68]	[45,198,91,62]	6	hSpCas9	negative selection	6526835
15724970	15724993	16	-	27260156	CORL105	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.5380982655411877	[626]	[467,462,598,505]	-7	hSpCas9	negative selection	6591091
15838216	15838239	16	+	27260156	CORL105	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.4744255177842273	[431]	[317,311,351,470]	-7	hSpCas9	negative selection	6591092
15724944	15724967	16	-	27260156	CORL105	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.1355642394206793	[250]	[231,200,232,397]	-3	hSpCas9	negative selection	6591093
15838142	15838165	16	-	27260156	HS294T	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.6853053705048993	[63]	[30,27,37,67]	8	hSpCas9	negative selection	6648084
15724187	15724210	16	-	27260156	HS294T	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.4898543861728889	[580]	[295,241,397,331]	6	hSpCas9	negative selection	6648085
15724217	15724240	16	-	27260156	HS294T	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	-0.16398908678451862	[68]	[40,9,23,17]	-2	hSpCas9	negative selection	6648086
15724970	15724993	16	-	27260156	HS294T	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-1.0747047952462587	[626]	[62,92,118,205]	-9	hSpCas9	negative selection	6712342
15838216	15838239	16	+	27260156	HS294T	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.18839123013248976	[431]	[136,146,164,343]	2	hSpCas9	negative selection	6712343
15724944	15724967	16	-	27260156	HS294T	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.1320830079834685	[250]	[108,64,106,152]	1	hSpCas9	negative selection	6712344
15838142	15838165	16	-	27260156	HCC44	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.5250189839496451	[63]	[102,84,175,67]	8	hSpCas9	negative selection	6769335
15724187	15724210	16	-	27260156	HCC44	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.1802227372947397	[580]	[877,765,663,661]	3	hSpCas9	negative selection	6769336
15724217	15724240	16	-	27260156	HCC44	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.9884589211911612	[68]	[97,110,300,134]	9	hSpCas9	negative selection	6769337
15724970	15724993	16	-	27260156	HCC44	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.22695919264337366	[626]	[848,622,543,417]	-4	hSpCas9	negative selection	6833593
15838216	15838239	16	+	27260156	HCC44	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.22629251522204455	[431]	[565,462,834,480]	3	hSpCas9	negative selection	6833594
15724944	15724967	16	-	27260156	HCC44	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.0037207833096695175	[250]	[322,151,450,261]	0	hSpCas9	negative selection	6833595
15838142	15838165	16	-	27260156	G402	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.053921552370822745	[63]	[63,182,32,48]	0	hSpCas9	negative selection	6890586
15724187	15724210	16	-	27260156	G402	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	-0.2598609662040038	[580]	[703,555,292,815]	-3	hSpCas9	negative selection	6890587
15724217	15724240	16	-	27260156	G402	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	1.3089360547039057	[68]	[468,84,58,248]	9	hSpCas9	negative selection	6890588
15724970	15724993	16	-	27260156	G402	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.05491200808171992	[626]	[1044,843,772,350]	0	hSpCas9	negative selection	6954844
15838216	15838239	16	+	27260156	G402	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.006550238576323794	[431]	[603,524,594,390]	0	hSpCas9	negative selection	6954845
15724944	15724967	16	-	27260156	G402	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.1468540414580417	[250]	[277,259,296,269]	-2	hSpCas9	negative selection	6954846
15838142	15838165	16	-	27260156	L33	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.09169929145976097	[63]	[51,30,28,98]	2	hSpCas9	negative selection	7011837
15724187	15724210	16	-	27260156	L33	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.2091464180461422	[580]	[823,272,369,603]	4	hSpCas9	negative selection	7011838
15724217	15724240	16	-	27260156	L33	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	-0.18908057488752883	[68]	[99,11,29,63]	-4	hSpCas9	negative selection	7011839
15724970	15724993	16	-	27260156	L33	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.2789812288710976	[626]	[474,201,416,437]	-6	hSpCas9	negative selection	7076095
15838216	15838239	16	+	27260156	L33	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.220029755299395	[431]	[459,210,325,519]	5	hSpCas9	negative selection	7076096
15724944	15724967	16	-	27260156	L33	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.2011277304628063	[250]	[311,102,83,173]	-4	hSpCas9	negative selection	7076097
15838142	15838165	16	-	27260156	K562	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.6754964564034633	[63]	[111,159,100,4]	8	hSpCas9	negative selection	7133088
15724187	15724210	16	-	27260156	K562	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.3915941928579747	[580]	[629,708,896,486]	5	hSpCas9	negative selection	7133089
15724217	15724240	16	-	27260156	K562	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.4403724480706197	[68]	[103,77,82,69]	5	hSpCas9	negative selection	7133090
15724970	15724993	16	-	27260156	K562	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.3118419533508458	[626]	[587,474,245,489]	-4	hSpCas9	negative selection	7197346
15838216	15838239	16	+	27260156	K562	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.5304618200455742	[431]	[398,293,293,104]	-6	hSpCas9	negative selection	7197347
15724944	15724967	16	-	27260156	K562	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.5681830899979408	[250]	[160,200,111,131]	-6	hSpCas9	negative selection	7197348
15838142	15838165	16	-	27260156	HT29	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.5676179266246266	[63]	[107,132,119,101]	9	hSpCas9	negative selection	7254339
15724187	15724210	16	-	27260156	HT29	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.2487630780740322	[580]	[1023,937,775,657]	5	hSpCas9	negative selection	7254340
15724217	15724240	16	-	27260156	HT29	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.7815454360058285	[68]	[123,105,197,142]	9	hSpCas9	negative selection	7254341
15724970	15724993	16	-	27260156	HT29	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.11005420480915035	[626]	[876,698,673,595]	-2	hSpCas9	negative selection	7318597
15838216	15838239	16	+	27260156	HT29	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.08698794884022874	[431]	[497,419,564,485]	-2	hSpCas9	negative selection	7318598
15724944	15724967	16	-	27260156	HT29	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.004401652263763323	[250]	[315,311,295,299]	0	hSpCas9	negative selection	7318599
15838142	15838165	16	-	27260156	MHHES1	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.7887388775106281	[63]	[141,235,71,70]	9	hSpCas9	negative selection	7375590
15724187	15724210	16	-	27260156	MHHES1	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.09407982430599304	[580]	[768,765,831,478]	1	hSpCas9	negative selection	7375591
15724217	15724240	16	-	27260156	MHHES1	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.5849653491525246	[68]	[68,184,85,122]	8	hSpCas9	negative selection	7375592
15724970	15724993	16	-	27260156	MHHES1	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.49123120317425667	[626]	[611,618,467,357]	-7	hSpCas9	negative selection	7439848
15838216	15838239	16	+	27260156	MHHES1	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.12612316521036954	[431]	[442,433,365,511]	-2	hSpCas9	negative selection	7439849
15724944	15724967	16	-	27260156	MHHES1	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.4811308452055063	[250]	[273,221,129,191]	-7	hSpCas9	negative selection	7439850
15838142	15838165	16	-	27260156	MEWO	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.8820673269991588	[63]	[130,116,86]	9	hSpCas9	negative selection	7496841
15724187	15724210	16	-	27260156	MEWO	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	-0.10649775044827231	[580]	[623,424,488]	-2	hSpCas9	negative selection	7496842
15724217	15724240	16	-	27260156	MEWO	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.4588863231173117	[68]	[92,86,86]	8	hSpCas9	negative selection	7496843
15724970	15724993	16	-	27260156	MEWO	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.20694065334441988	[626]	[524,461,540]	-4	hSpCas9	negative selection	7561099
15838216	15838239	16	+	27260156	MEWO	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.08975905120005233	[431]	[435,411,301]	-2	hSpCas9	negative selection	7561100
15724944	15724967	16	-	27260156	MEWO	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.3535764238733349	[250]	[218,373,290]	7	hSpCas9	negative selection	7561101
15838142	15838165	16	-	27260156	LNCAPCLONEFGC	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	1.045825835327506	[63]	[82,82,194,131]	9	hSpCas9	negative selection	7618092
15724187	15724210	16	-	27260156	LNCAPCLONEFGC	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	-0.13031161299821634	[580]	[489,455,510,471]	-2	hSpCas9	negative selection	7618093
15724217	15724240	16	-	27260156	LNCAPCLONEFGC	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.35342375374615864	[68]	[75,78,89,75]	5	hSpCas9	negative selection	7618094
15724970	15724993	16	-	27260156	LNCAPCLONEFGC	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.2481089083749976	[626]	[277,551,527,560]	-4	hSpCas9	negative selection	7682350
15838216	15838239	16	+	27260156	LNCAPCLONEFGC	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.007293720002315943	[431]	[276,384,515,415]	0	hSpCas9	negative selection	7682351
15724944	15724967	16	-	27260156	LNCAPCLONEFGC	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.047938140514625416	[250]	[174,163,366,199]	0	hSpCas9	negative selection	7682352
15838142	15838165	16	-	27260156	PANC0327	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	-0.3575874085052817	[63]	[9,11,134,21]	-5	hSpCas9	negative selection	7739343
15724187	15724210	16	-	27260156	PANC0327	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	-0.14604387190124374	[580]	[747,399,330,417]	-2	hSpCas9	negative selection	7739344
15724217	15724240	16	-	27260156	PANC0327	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.31253521538283247	[68]	[94,52,83,76]	4	hSpCas9	negative selection	7739345
15724970	15724993	16	-	27260156	PANC0327	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	0.0827469271245343	[626]	[772,669,564,355]	1	hSpCas9	negative selection	7803601
15838216	15838239	16	+	27260156	PANC0327	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.10722453327341844	[431]	[488,257,628,303]	1	hSpCas9	negative selection	7803602
15724944	15724967	16	-	27260156	PANC0327	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.17679835356159224	[250]	[228,101,287,184]	-3	hSpCas9	negative selection	7803603
15838142	15838165	16	-	27260156	NCIH2009	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.20843678706759317	[63]	[98,98,110]	3	hSpCas9	negative selection	7860594
15724187	15724210	16	-	27260156	NCIH2009	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.0251932496128065	[580]	[856,652,975]	0	hSpCas9	negative selection	7860595
15724217	15724240	16	-	27260156	NCIH2009	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.06258858703074077	[68]	[106,161,32]	0	hSpCas9	negative selection	7860596
15724970	15724993	16	-	27260156	NCIH2009	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.7186832034755739	[626]	[623,485,504]	-7	hSpCas9	negative selection	7924852
15838216	15838239	16	+	27260156	NCIH2009	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.04915802235730356	[431]	[590,504,655]	0	hSpCas9	negative selection	7924853
15724944	15724967	16	-	27260156	NCIH2009	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.07800532349760736	[250]	[458,286,275]	-1	hSpCas9	negative selection	7924854
15838142	15838165	16	-	27260156	NCIH1373	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	-0.0664531118968199	[63]	[109,37,73,15]	0	hSpCas9	negative selection	7981845
15724187	15724210	16	-	27260156	NCIH1373	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.04855090733171402	[580]	[927,407,943,120]	0	hSpCas9	negative selection	7981846
15724217	15724240	16	-	27260156	NCIH1373	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	1.141160715065904	[68]	[328,126,158,23]	9	hSpCas9	negative selection	7981847
15724970	15724993	16	-	27260156	NCIH1373	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.7726756259568107	[626]	[190,282,625,137]	-7	hSpCas9	negative selection	8046103
15838216	15838239	16	+	27260156	NCIH1373	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.05335326776781159	[431]	[415,672,472,67]	0	hSpCas9	negative selection	8046104
15724944	15724967	16	-	27260156	NCIH1373	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.7135282525455351	[250]	[147,153,261,29]	-6	hSpCas9	negative selection	8046105
15838142	15838165	16	-	27260156	PATU8902	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	1.7997355806137894	[63]	[353,186,210,538]	9	hSpCas9	negative selection	8103096
15724187	15724210	16	-	27260156	PATU8902	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.34058525886382973	[580]	[1130,1296,620,1161]	3	hSpCas9	negative selection	8103097
15724217	15724240	16	-	27260156	PATU8902	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	1.2563329403943693	[68]	[374,125,226,180]	9	hSpCas9	negative selection	8103098
15724970	15724993	16	-	27260156	PATU8902	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.8789641337012308	[626]	[459,410,248,882]	-7	hSpCas9	negative selection	8167354
15838216	15838239	16	+	27260156	PATU8902	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.42869724795659375	[431]	[418,548,935,1366]	4	hSpCas9	negative selection	8167355
15724944	15724967	16	-	27260156	PATU8902	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.11485188132310109	[250]	[444,351,357,357]	1	hSpCas9	negative selection	8167356
15838142	15838165	16	-	27260156	PANC1	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.3966638428745912	[63]	[60,119,83,38]	6	hSpCas9	negative selection	8224347
15724187	15724210	16	-	27260156	PANC1	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	-0.13526826484845092	[580]	[518,461,477,365]	-2	hSpCas9	negative selection	8224348
15724217	15724240	16	-	27260156	PANC1	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.280083505032799	[68]	[60,80,82,64]	4	hSpCas9	negative selection	8224349
15724970	15724993	16	-	27260156	PANC1	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.351360119407817	[626]	[393,544,466,318]	-5	hSpCas9	negative selection	8288605
15838216	15838239	16	+	27260156	PANC1	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.14157218149690692	[431]	[412,230,319,349]	-2	hSpCas9	negative selection	8288606
15724944	15724967	16	-	27260156	PANC1	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.2196817707912757	[250]	[212,218,130,180]	-4	hSpCas9	negative selection	8288607
15838142	15838165	16	-	27260156	PANC0813	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.11414773125474875	[63]	[68,87,47,116]	1	hSpCas9	negative selection	8345598
15724187	15724210	16	-	27260156	PANC0813	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.359979859781707	[580]	[941,777,544,1221]	6	hSpCas9	negative selection	8345599
15724217	15724240	16	-	27260156	PANC0813	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.1028403646809215	[68]	[111,79,66,90]	1	hSpCas9	negative selection	8345600
15724970	15724993	16	-	27260156	PANC0813	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.7439439556122878	[626]	[552,505,355,357]	-8	hSpCas9	negative selection	8409856
15838216	15838239	16	+	27260156	PANC0813	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.135462839603737	[431]	[600,430,476,356]	-2	hSpCas9	negative selection	8409857
15724944	15724967	16	-	27260156	PANC0813	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.19215594450816065	[250]	[375,267,222,179]	-3	hSpCas9	negative selection	8409858
15838142	15838165	16	-	27260156	RDES	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.6245208378847282	[63]	[82,125,160,82]	8	hSpCas9	negative selection	8466849
15724187	15724210	16	-	27260156	RDES	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.07691374083285318	[580]	[486,696,843,845]	1	hSpCas9	negative selection	8466850
15724217	15724240	16	-	27260156	RDES	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.7423536651529594	[68]	[150,103,130,139]	9	hSpCas9	negative selection	8466851
15724970	15724993	16	-	27260156	RDES	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.41134525213173745	[626]	[468,564,543,594]	-6	hSpCas9	negative selection	8531107
15838216	15838239	16	+	27260156	RDES	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.09399294093442778	[431]	[409,541,677,500]	1	hSpCas9	negative selection	8531108
15724944	15724967	16	-	27260156	RDES	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.19584494156761045	[250]	[237,265,250,244]	-3	hSpCas9	negative selection	8531109
15838142	15838165	16	-	27260156	PC3	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.2987787113579241	[63]	[66,38,90,120]	6	hSpCas9	negative selection	8588100
15724187	15724210	16	-	27260156	PC3	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.12292043725470242	[580]	[325,661,1349,540]	2	hSpCas9	negative selection	8588101
15724217	15724240	16	-	27260156	PC3	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.3232944001369158	[68]	[38,90,119,122]	7	hSpCas9	negative selection	8588102
15724970	15724993	16	-	27260156	PC3	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	0.036848128765349875	[626]	[415,646,1160,573]	0	hSpCas9	negative selection	8652358
15838216	15838239	16	+	27260156	PC3	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.26124790655421987	[431]	[351,386,685,740]	5	hSpCas9	negative selection	8652359
15724944	15724967	16	-	27260156	PC3	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.10376462526598174	[250]	[129,182,496,405]	2	hSpCas9	negative selection	8652360
15838142	15838165	16	-	27260156	PATU8988T	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	1.0025717789967183	[63]	[177,135,104,73]	9	hSpCas9	negative selection	8709351
15724187	15724210	16	-	27260156	PATU8988T	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	-0.24676684566074408	[580]	[389,497,366,655]	-4	hSpCas9	negative selection	8709352
15724217	15724240	16	-	27260156	PATU8988T	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.7660669869508165	[68]	[78,164,164,42]	9	hSpCas9	negative selection	8709353
15724970	15724993	16	-	27260156	PATU8988T	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.22346596219697037	[626]	[526,727,498,325]	-4	hSpCas9	negative selection	8773609
15838216	15838239	16	+	27260156	PATU8988T	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.018989191498639507	[431]	[385,557,461,286]	0	hSpCas9	negative selection	8773610
15724944	15724967	16	-	27260156	PATU8988T	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.2108345033265172	[250]	[253,280,183,415]	3	hSpCas9	negative selection	8773611
15838142	15838165	16	-	27260156	T47D	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.149272138858918	[63]	[84,71,81,92]	3	hSpCas9	negative selection	8830602
15724187	15724210	16	-	27260156	T47D	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.11788960996397518	[580]	[617,591,826,916]	2	hSpCas9	negative selection	8830603
15724217	15724240	16	-	27260156	T47D	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.25411516999927697	[68]	[96,85,87,113]	5	hSpCas9	negative selection	8830604
15724970	15724993	16	-	27260156	T47D	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.37668551044504883	[626]	[512,621,547,561]	-7	hSpCas9	negative selection	8894860
15838216	15838239	16	+	27260156	T47D	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.04290598915432674	[431]	[461,458,555,477]	-1	hSpCas9	negative selection	8894861
15724944	15724967	16	-	27260156	T47D	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.07491007399501659	[250]	[376,263,293,300]	1	hSpCas9	negative selection	8894862
15838142	15838165	16	-	27260156	SU8686	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.3091777948238481	[63]	[46,90,108,67]	5	hSpCas9	negative selection	8951853
15724187	15724210	16	-	27260156	SU8686	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.30234313494645104	[580]	[616,645,767,847]	5	hSpCas9	negative selection	8951854
15724217	15724240	16	-	27260156	SU8686	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.38342226400853363	[68]	[107,62,120,61]	6	hSpCas9	negative selection	8951855
15724970	15724993	16	-	27260156	SU8686	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.5791337483866075	[626]	[331,398,449,507]	-7	hSpCas9	negative selection	9016111
15838216	15838239	16	+	27260156	SU8686	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.04479115334588182	[431]	[459,396,378,546]	0	hSpCas9	negative selection	9016112
15724944	15724967	16	-	27260156	SU8686	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.021800351299902876	[250]	[194,313,230,232]	0	hSpCas9	negative selection	9016113
15838142	15838165	16	-	27260156	SKES1	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.2511456877951175	[63]	[114,44,69,74]	5	hSpCas9	negative selection	9073104
15724187	15724210	16	-	27260156	SKES1	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.06139117982876152	[580]	[651,723,594,477]	1	hSpCas9	negative selection	9073105
15724217	15724240	16	-	27260156	SKES1	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.6354918882504057	[68]	[99,139,135,58]	9	hSpCas9	negative selection	9073106
15724970	15724993	16	-	27260156	SKES1	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.09798940557452207	[626]	[692,681,519,476]	-2	hSpCas9	negative selection	9137362
15838216	15838239	16	+	27260156	SKES1	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	0.028531833160893083	[431]	[590,463,445,293]	0	hSpCas9	negative selection	9137363
15724944	15724967	16	-	27260156	SKES1	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.1717453522298784	[250]	[165,337,306,301]	3	hSpCas9	negative selection	9137364
15838142	15838165	16	-	27260156	TOV112D	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.6655123264524296	[63]	[56,120,181,48]	9	hSpCas9	negative selection	9194355
15724187	15724210	16	-	27260156	TOV112D	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.07340803386273731	[580]	[722,632,656,453]	1	hSpCas9	negative selection	9194356
15724217	15724240	16	-	27260156	TOV112D	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.3172776969349873	[68]	[80,137,28,107]	6	hSpCas9	negative selection	9194357
15724970	15724993	16	-	27260156	TOV112D	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.44499112319498524	[626]	[394,438,415,579]	-7	hSpCas9	negative selection	9258613
15838216	15838239	16	+	27260156	TOV112D	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.34985026150659104	[431]	[318,449,313,300]	-6	hSpCas9	negative selection	9258614
15724944	15724967	16	-	27260156	TOV112D	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	-0.08671282048541495	[250]	[299,266,253,140]	-2	hSpCas9	negative selection	9258615
15838142	15838165	16	-	27260156	TC71	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	-0.03703190495696429	[63]	[57,80,79,46]	-1	hSpCas9	negative selection	9315606
15724187	15724210	16	-	27260156	TC71	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	-0.013676188861575622	[580]	[593,767,544,559]	0	hSpCas9	negative selection	9315607
15724217	15724240	16	-	27260156	TC71	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.10416558330779901	[68]	[63,70,68,116]	2	hSpCas9	negative selection	9315608
15724970	15724993	16	-	27260156	TC71	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.21314331286109386	[626]	[673,601,462,581]	-5	hSpCas9	negative selection	9379864
15838216	15838239	16	+	27260156	TC71	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.16401737572830327	[431]	[523,432,343,347]	-4	hSpCas9	negative selection	9379865
15724944	15724967	16	-	27260156	TC71	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.023998945511948255	[250]	[283,219,261,331]	0	hSpCas9	negative selection	9379866
15838142	15838165	16	-	27260156	TC32	viability	GGGCCGCCAAGAGACTCGTCTGG	MYH11	ENSG00000133392	0.8751266675657488	[63]	[103,113,110,103]	9	hSpCas9	negative selection	9436857
15724187	15724210	16	-	27260156	TC32	viability	GCGGCAACTCGTGTCCAACCTGG	MYH11	ENSG00000133392	0.04921878371761029	[580]	[463,410,822,649]	0	hSpCas9	negative selection	9436858
15724217	15724240	16	-	27260156	TC32	viability	GGACGACCTGGTTGTTGATTTGG	MYH11	ENSG00000133392	0.6732426976164718	[68]	[68,85,127,141]	9	hSpCas9	negative selection	9436859
15724970	15724993	16	-	27260156	TC32	viability	AATGAAGTTGAGAGCGTCACAGG	MYH11	ENSG00000133392	-0.4837374442637159	[626]	[403,237,584,541]	-7	hSpCas9	negative selection	9501115
15838216	15838239	16	+	27260156	TC32	viability	ACTTCTCATCGTCACTGAGTTGG	MYH11	ENSG00000133392	-0.1231895522121884	[431]	[323,277,517,418]	-2	hSpCas9	negative selection	9501116
15724944	15724967	16	-	27260156	TC32	viability	GCTTAACGAGGCCGAGGGGAAGG	MYH11	ENSG00000133392	0.2320485276838059	[250]	[330,224,344,209]	4	hSpCas9	negative selection	9501117
15760640	15760663	16	+	27869803	HPAFII	viability after 27 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.8463047210934309	[311]	[301,288,NaN]	7	hSpCas9	negative selection	9555769
15771581	15771604	16	-	27869803	HPAFII	viability after 27 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	1.124145588385343	[212]	[344,159,NaN]	8	hSpCas9	negative selection	9555770
15776130	15776153	16	-	27869803	HPAFII	viability after 27 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.020012872630619682	[653]	[328,364,NaN]	0	hSpCas9	negative selection	9555771
15786653	15786676	16	-	27869803	HPAFII	viability after 27 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.3640479818025142	[324]	[388,78,NaN]	3	hSpCas9	negative selection	9555772
15823268	15823291	16	+	27869803	HPAFII	viability after 27 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.9459739401753098	[332]	[489,209,NaN]	7	hSpCas9	negative selection	9555773
15837929	15837952	16	-	27869803	HPAFII	viability after 27 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	0.981948929131488	[489]	[420,581,NaN]	7	hSpCas9	negative selection	9555776
15760640	15760663	16	+	27869803	HPAFII	viability after 15 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	1.3556563635644079	[311]	[875,846,NaN]	9	hSpCas9	negative selection	9638218
15771581	15771604	16	-	27869803	HPAFII	viability after 15 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	1.016250540778542	[212]	[684,324,NaN]	9	hSpCas9	negative selection	9638219
15776130	15776153	16	-	27869803	HPAFII	viability after 15 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	-0.03230938401438843	[653]	[1113,421,NaN]	0	hSpCas9	negative selection	9638220
15786653	15786676	16	-	27869803	HPAFII	viability after 15 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.6464230239994504	[324]	[719,438,NaN]	7	hSpCas9	negative selection	9638221
15823268	15823291	16	+	27869803	HPAFII	viability after 15 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.3915201120747008	[332]	[622,373,NaN]	4	hSpCas9	negative selection	9638222
15837929	15837952	16	-	27869803	HPAFII	viability after 15 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	0.4261182169481563	[489]	[923,572,NaN]	5	hSpCas9	negative selection	9638225
15760640	15760663	16	+	27869803	ASPC1	viability after 36 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	-0.7433230740053204	[906]	[210,106,236]	-6	hSpCas9	negative selection	9720667
15771581	15771604	16	-	27869803	ASPC1	viability after 36 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	0.713609951090914	[837]	[643,352,459]	7	hSpCas9	negative selection	9720668
15776130	15776153	16	-	27869803	ASPC1	viability after 36 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	1.0047485654761656	[1441]	[493,667,1632]	8	hSpCas9	negative selection	9720669
15786653	15786676	16	-	27869803	ASPC1	viability after 36 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.3575036122184021	[1328]	[457,1000,360]	3	hSpCas9	negative selection	9720670
15823268	15823291	16	+	27869803	ASPC1	viability after 36 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	-0.13602822510070856	[885]	[414,352,127]	-1	hSpCas9	negative selection	9720671
15837929	15837952	16	-	27869803	ASPC1	viability after 36 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	-0.011158759778426841	[1279]	[620,411,338]	0	hSpCas9	negative selection	9720674
15760640	15760663	16	+	27869803	PATU8988S	viability after 35 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.8463672510016154	[706]	[494,528,NaN]	8	hSpCas9	negative selection	9803116
15771581	15771604	16	-	27869803	PATU8988S	viability after 35 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.25151452104219496	[725]	[296,193,NaN]	-3	hSpCas9	negative selection	9803117
15776130	15776153	16	-	27869803	PATU8988S	viability after 35 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.2890883106514397	[1135]	[354,763,NaN]	3	hSpCas9	negative selection	9803118
15786653	15786676	16	-	27869803	PATU8988S	viability after 35 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-0.8103702869858758	[1099]	[308,195,NaN]	-7	hSpCas9	negative selection	9803119
15823268	15823291	16	+	27869803	PATU8988S	viability after 35 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	-0.2458751548766248	[722]	[271,218,NaN]	-3	hSpCas9	negative selection	9803120
15837929	15837952	16	-	27869803	PATU8988S	viability after 35 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	0.003154354829273953	[1059]	[361,493,NaN]	0	hSpCas9	negative selection	9803123
15760640	15760663	16	+	27869803	PATU8988S	viability after 31 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.6307273882423055	[706]	[322,580,NaN]	7	hSpCas9	negative selection	9885565
15771581	15771604	16	-	27869803	PATU8988S	viability after 31 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	-0.22040790648584527	[725]	[218,285,NaN]	-3	hSpCas9	negative selection	9885566
15776130	15776153	16	-	27869803	PATU8988S	viability after 31 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.23578550018615219	[1135]	[323,799,NaN]	3	hSpCas9	negative selection	9885567
15786653	15786676	16	-	27869803	PATU8988S	viability after 31 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	-0.44875125786298664	[1099]	[345,289,NaN]	-5	hSpCas9	negative selection	9885568
15823268	15823291	16	+	27869803	PATU8988S	viability after 31 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	-0.41971155715998454	[722]	[211,219,NaN]	-5	hSpCas9	negative selection	9885569
15837929	15837952	16	-	27869803	PATU8988S	viability after 31 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	-0.012317293912609606	[1059]	[393,450,NaN]	0	hSpCas9	negative selection	9885572
15760640	15760663	16	+	27869803	HPAFII	viability after 35 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.8507439291779395	[311]	[218,358,NaN]	5	hSpCas9	negative selection	9968014
15771581	15771604	16	-	27869803	HPAFII	viability after 35 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	1.6455395998310658	[212]	[358,312,NaN]	9	hSpCas9	negative selection	9968015
15776130	15776153	16	-	27869803	HPAFII	viability after 35 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.05108961594062644	[653]	[382,297,NaN]	0	hSpCas9	negative selection	9968016
15786653	15786676	16	-	27869803	HPAFII	viability after 35 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.25494428674521596	[324]	[272,109,NaN]	1	hSpCas9	negative selection	9968017
15823268	15823291	16	+	27869803	HPAFII	viability after 35 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.7838575311961069	[332]	[317,258,NaN]	5	hSpCas9	negative selection	9968018
15837929	15837952	16	-	27869803	HPAFII	viability after 35 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	1.7079043878213602	[489]	[387,1285,NaN]	9	hSpCas9	negative selection	9968021
15760640	15760663	16	+	27869803	HPAFII	viability after 31 days	TGGCAAACTTTCTGAGCAGCTGG	MYH11	ENSG00000133392	0.6122498244704249	[311]	[248,287,NaN]	4	hSpCas9	negative selection	10050463
15771581	15771604	16	-	27869803	HPAFII	viability after 31 days	GGCAATCATGGGTTTCAGCGAGG	MYH11	ENSG00000133392	1.2745496884155283	[212]	[326,247,NaN]	8	hSpCas9	negative selection	10050464
15776130	15776153	16	-	27869803	HPAFII	viability after 31 days	TTCGCCAAGCCAGAGACGAGAGG	MYH11	ENSG00000133392	0.07633424466355199	[653]	[352,423,NaN]	0	hSpCas9	negative selection	10050465
15786653	15786676	16	-	27869803	HPAFII	viability after 31 days	CGTGGTGGCCTCCTCCCACAAGG	MYH11	ENSG00000133392	0.08792537512069082	[324]	[212,172,NaN]	0	hSpCas9	negative selection	10050466
15823268	15823291	16	+	27869803	HPAFII	viability after 31 days	CCGGTAGGCCGTGTCTGCGATGG	MYH11	ENSG00000133392	0.6494880791131064	[332]	[329,252,NaN]	5	hSpCas9	negative selection	10050467
15837929	15837952	16	-	27869803	HPAFII	viability after 31 days	TGCTACACAACCTGAGGGAGCGG	MYH11	ENSG00000133392	1.0943185681119318	[489]	[422,765,NaN]	7	hSpCas9	negative selection	10050470
15745159	15745182	16	-	28162770	P31FUJ	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	-0.1256833594444	[505]	[544]	-1	hSpCas9	negative selection	10196430
15724733	15724756	16	-	28162770	P31FUJ	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	-1.554730299301741	[29]	[11]	-7	hSpCas9	negative selection	10196431
15720952	15720975	16	-	28162770	P31FUJ	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.6861831072125618	[292]	[553]	7	hSpCas9	negative selection	10196432
15838096	15838119	16	-	28162770	P31FUJ	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	-0.10397222406942608	[181]	[198]	-1	hSpCas9	negative selection	10196433
15838042	15838065	16	-	28162770	P31FUJ	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-0.5995845350860013	[195]	[151]	-5	hSpCas9	negative selection	10196434
15771611	15771634	16	-	28162770	P31FUJ	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.42231352321722315	[387]	[610]	5	hSpCas9	negative selection	10196435
15763817	15763840	16	-	28162770	P31FUJ	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	0.17952091016742933	[398]	[530]	2	hSpCas9	negative selection	10196436
15759614	15759637	16	+	28162770	P31FUJ	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.4394939621941003	[218]	[348]	5	hSpCas9	negative selection	10196437
15756486	15756509	16	+	28162770	P31FUJ	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	0.18114523433592433	[330]	[440]	2	hSpCas9	negative selection	10196438
15745159	15745182	16	-	28162770	TF1	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	NaN	[NaN]	[523]	1	hSpCas9	negative selection	10365796
15724733	15724756	16	-	28162770	TF1	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10365797
15720952	15720975	16	-	28162770	TF1	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	NaN	[NaN]	[297]	1	hSpCas9	negative selection	10365798
15838096	15838119	16	-	28162770	TF1	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	NaN	[NaN]	[106]	1	hSpCas9	negative selection	10365799
15838042	15838065	16	-	28162770	TF1	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10365800
15771611	15771634	16	-	28162770	TF1	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	NaN	[NaN]	[245]	1	hSpCas9	negative selection	10365801
15763817	15763840	16	-	28162770	TF1	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	NaN	[NaN]	[354]	1	hSpCas9	negative selection	10365802
15759614	15759637	16	+	28162770	TF1	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	NaN	[NaN]	[230]	1	hSpCas9	negative selection	10365803
15756486	15756509	16	+	28162770	TF1	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10365804
15745159	15745182	16	-	28162770	SKM1	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.05472692707626048	[115]	[212]	0	hSpCas9	negative selection	10535162
15724733	15724756	16	-	28162770	SKM1	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	-0.04439411935845339	[6]	[11]	0	hSpCas9	negative selection	10535163
15720952	15720975	16	-	28162770	SKM1	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.46612368877461874	[94]	[231]	4	hSpCas9	negative selection	10535164
15838096	15838119	16	-	28162770	SKM1	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	-0.3150417093021227	[37]	[53]	-3	hSpCas9	negative selection	10535165
15838042	15838065	16	-	28162770	SKM1	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	0.10506677952414328	[70]	[134]	1	hSpCas9	negative selection	10535166
15771611	15771634	16	-	28162770	SKM1	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.015726873079117354	[93]	[167]	0	hSpCas9	negative selection	10535167
15763817	15763840	16	-	28162770	SKM1	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	-0.1195456342824085	[109]	[178]	-1	hSpCas9	negative selection	10535168
15759614	15759637	16	+	28162770	SKM1	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	1.255241300910455	[49]	[210]	9	hSpCas9	negative selection	10535169
15756486	15756509	16	+	28162770	SKM1	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	-0.23028183112554046	[70]	[106]	-2	hSpCas9	negative selection	10535170
15745159	15745182	16	-	28162770	SKM1	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.05472692707626048	[115]	[212]	0	hSpCas9	negative selection	10704528
15724733	15724756	16	-	28162770	SKM1	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	-0.04439411935845339	[6]	[11]	0	hSpCas9	negative selection	10704529
15720952	15720975	16	-	28162770	SKM1	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.46612368877461874	[94]	[231]	4	hSpCas9	negative selection	10704530
15838096	15838119	16	-	28162770	SKM1	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	-0.3150417093021227	[37]	[53]	-3	hSpCas9	negative selection	10704531
15838042	15838065	16	-	28162770	SKM1	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	0.10506677952414328	[70]	[134]	1	hSpCas9	negative selection	10704532
15771611	15771634	16	-	28162770	SKM1	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.015726873079117354	[93]	[167]	0	hSpCas9	negative selection	10704533
15763817	15763840	16	-	28162770	SKM1	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	-0.1195456342824085	[109]	[178]	-1	hSpCas9	negative selection	10704534
15759614	15759637	16	+	28162770	SKM1	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	1.255241300910455	[49]	[210]	9	hSpCas9	negative selection	10704535
15756486	15756509	16	+	28162770	SKM1	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	-0.23028183112554046	[70]	[106]	-2	hSpCas9	negative selection	10704536
15745159	15745182	16	-	28162770	PL21	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.30945630883282005	[342]	[184]	2	hSpCas9	negative selection	10873894
15724733	15724756	16	-	28162770	PL21	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	-0.4321286010101928	[30]	[9]	-3	hSpCas9	negative selection	10873895
15720952	15720975	16	-	28162770	PL21	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.4075816943597965	[290]	[167]	3	hSpCas9	negative selection	10873896
15838096	15838119	16	-	28162770	PL21	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	0.8538148652944906	[163]	[128]	7	hSpCas9	negative selection	10873897
15838042	15838065	16	-	28162770	PL21	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	0.23305423696205524	[259]	[132]	2	hSpCas9	negative selection	10873898
15771611	15771634	16	-	28162770	PL21	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	1.2049727682252636	[297]	[298]	8	hSpCas9	negative selection	10873899
15763817	15763840	16	-	28162770	PL21	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	0.7004244003866751	[344]	[243]	6	hSpCas9	negative selection	10873900
15759614	15759637	16	+	28162770	PL21	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.11921961910575267	[164]	[77]	1	hSpCas9	negative selection	10873901
15756486	15756509	16	+	28162770	PL21	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	1.234409516574066	[207]	[212]	8	hSpCas9	negative selection	10873902
15745159	15745182	16	-	28162770	P31FUJ	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	-0.1256833594444	[505]	[544]	-1	hSpCas9	negative selection	11043260
15724733	15724756	16	-	28162770	P31FUJ	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	-1.554730299301741	[29]	[11]	-7	hSpCas9	negative selection	11043261
15720952	15720975	16	-	28162770	P31FUJ	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.6861831072125618	[292]	[553]	7	hSpCas9	negative selection	11043262
15838096	15838119	16	-	28162770	P31FUJ	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	-0.10397222406942608	[181]	[198]	-1	hSpCas9	negative selection	11043263
15838042	15838065	16	-	28162770	P31FUJ	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-0.5995845350860013	[195]	[151]	-5	hSpCas9	negative selection	11043264
15771611	15771634	16	-	28162770	P31FUJ	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.42231352321722315	[387]	[610]	5	hSpCas9	negative selection	11043265
15763817	15763840	16	-	28162770	P31FUJ	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	0.17952091016742933	[398]	[530]	2	hSpCas9	negative selection	11043266
15759614	15759637	16	+	28162770	P31FUJ	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.4394939621941003	[218]	[348]	5	hSpCas9	negative selection	11043267
15756486	15756509	16	+	28162770	P31FUJ	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	0.18114523433592433	[330]	[440]	2	hSpCas9	negative selection	11043268
15745159	15745182	16	-	28162770	OCIAML5	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	-0.061858955420811546	[265]	[459]	0	hSpCas9	negative selection	11212626
15724733	15724756	16	-	28162770	OCIAML5	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	1.3178584305783152	[13]	[62]	9	hSpCas9	negative selection	11212627
15720952	15720975	16	-	28162770	OCIAML5	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.7590087701762904	[145]	[445]	6	hSpCas9	negative selection	11212628
15838096	15838119	16	-	28162770	OCIAML5	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	-0.2905630429668299	[123]	[182]	-2	hSpCas9	negative selection	11212629
15838042	15838065	16	-	28162770	OCIAML5	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	0.06047058788566359	[101]	[191]	0	hSpCas9	negative selection	11212630
15771611	15771634	16	-	28162770	OCIAML5	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.6598324676674361	[161]	[461]	6	hSpCas9	negative selection	11212631
15763817	15763840	16	-	28162770	OCIAML5	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	0.43281453726804553	[212]	[518]	4	hSpCas9	negative selection	11212632
15759614	15759637	16	+	28162770	OCIAML5	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.6617048820002066	[89]	[256]	6	hSpCas9	negative selection	11212633
15756486	15756509	16	+	28162770	OCIAML5	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	0.44187911149748504	[176]	[433]	4	hSpCas9	negative selection	11212634
15745159	15745182	16	-	28162770	EOL1	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.8294652257168592	[438]	[410]	7	hSpCas9	negative selection	11381992
15724733	15724756	16	-	28162770	EOL1	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	-0.9421856975660012	[61]	[16]	-6	hSpCas9	negative selection	11381993
15720952	15720975	16	-	28162770	EOL1	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.33390536177702357	[508]	[337]	3	hSpCas9	negative selection	11381994
15838096	15838119	16	-	28162770	EOL1	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	0.3661460971205133	[295]	[200]	3	hSpCas9	negative selection	11381995
15838042	15838065	16	-	28162770	EOL1	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-0.9661048322411045	[507]	[136]	-6	hSpCas9	negative selection	11381996
15771611	15771634	16	-	28162770	EOL1	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	1.2624639016354604	[340]	[430]	9	hSpCas9	negative selection	11381997
15763817	15763840	16	-	28162770	EOL1	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	0.31517360480946466	[446]	[292]	3	hSpCas9	negative selection	11381998
15759614	15759637	16	+	28162770	EOL1	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.6236812922110018	[254]	[206]	5	hSpCas9	negative selection	11381999
15756486	15756509	16	+	28162770	EOL1	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	0.3481984011540863	[333]	[223]	3	hSpCas9	negative selection	11382000
15745159	15745182	16	-	28162770	MOLM13	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.8896737132640076	[479]	[642]	6	hSpCas9	negative selection	11551358
15724733	15724756	16	-	28162770	MOLM13	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	-0.7197376216311926	[40]	[17]	-4	hSpCas9	negative selection	11551359
15720952	15720975	16	-	28162770	MOLM13	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	1.402615827733229	[372]	[712]	9	hSpCas9	negative selection	11551360
15838096	15838119	16	-	28162770	MOLM13	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	0.14310728960206354	[252]	[201]	1	hSpCas9	negative selection	11551361
15838042	15838065	16	-	28162770	MOLM13	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-0.06836170470334557	[363]	[250]	0	hSpCas9	negative selection	11551362
15771611	15771634	16	-	28162770	MOLM13	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.23798468503310038	[352]	[300]	1	hSpCas9	negative selection	11551363
15763817	15763840	16	-	28162770	MOLM13	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	-0.33356493907334095	[548]	[314]	-2	hSpCas9	negative selection	11551364
15759614	15759637	16	+	28162770	MOLM13	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.1806074294641076	[215]	[176]	1	hSpCas9	negative selection	11551365
15756486	15756509	16	+	28162770	MOLM13	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	1.2469490942420434	[330]	[567]	8	hSpCas9	negative selection	11551366
15745159	15745182	16	-	28162770	HEL	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.16174425114537572	[454]	[325]	1	hSpCas9	negative selection	11720724
15724733	15724756	16	-	28162770	HEL	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	-1.1014222635700535	[66]	[19]	-6	hSpCas9	negative selection	11720725
15720952	15720975	16	-	28162770	HEL	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.5242799985919997	[443]	[408]	4	hSpCas9	negative selection	11720726
15838096	15838119	16	-	28162770	HEL	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	0.42676125022733746	[186]	[160]	3	hSpCas9	negative selection	11720727
15838042	15838065	16	-	28162770	HEL	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-0.2544503624158678	[351]	[188]	-2	hSpCas9	negative selection	11720728
15771611	15771634	16	-	28162770	HEL	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.9979264762516801	[282]	[361]	8	hSpCas9	negative selection	11720729
15763817	15763840	16	-	28162770	HEL	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	-0.8685517568400999	[438]	[153]	-5	hSpCas9	negative selection	11720730
15759614	15759637	16	+	28162770	HEL	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.16004438261825082	[210]	[150]	1	hSpCas9	negative selection	11720731
15756486	15756509	16	+	28162770	HEL	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	0.16274589088074326	[264]	[189]	1	hSpCas9	negative selection	11720732
15745159	15745182	16	-	28162770	MV411	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.022471185782500847	[373]	[319]	0	hSpCas9	negative selection	11890090
15724733	15724756	16	-	28162770	MV411	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	1.190854022416408	[25]	[49]	9	hSpCas9	negative selection	11890091
15720952	15720975	16	-	28162770	MV411	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.12529044149698476	[270]	[248]	1	hSpCas9	negative selection	11890092
15838096	15838119	16	-	28162770	MV411	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	-0.45584491712714226	[126]	[77]	-3	hSpCas9	negative selection	11890093
15838042	15838065	16	-	28162770	MV411	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-0.7421458332718864	[275]	[138]	-5	hSpCas9	negative selection	11890094
15771611	15771634	16	-	28162770	MV411	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	-0.45241487036633155	[306]	[188]	-3	hSpCas9	negative selection	11890095
15763817	15763840	16	-	28162770	MV411	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	-0.8183645076129709	[313]	[149]	-5	hSpCas9	negative selection	11890096
15759614	15759637	16	+	28162770	MV411	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.43074476414583507	[154]	[175]	4	hSpCas9	negative selection	11890097
15756486	15756509	16	+	28162770	MV411	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	-0.8934249850570742	[257]	[116]	-6	hSpCas9	negative selection	11890098
15745159	15745182	16	-	28162770	MONOMAC1	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.7677346646294647	[227]	[444]	7	hSpCas9	negative selection	12059456
15724733	15724756	16	-	28162770	MONOMAC1	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	0.025355574276893833	[29]	[34]	0	hSpCas9	negative selection	12059457
15720952	15720975	16	-	28162770	MONOMAC1	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	-0.33152217924657396	[190]	[173]	-3	hSpCas9	negative selection	12059458
15838096	15838119	16	-	28162770	MONOMAC1	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	0.3084911861671976	[111]	[158]	3	hSpCas9	negative selection	12059459
15838042	15838065	16	-	28162770	MONOMAC1	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-0.2921940800998939	[187]	[175]	-3	hSpCas9	negative selection	12059460
15771611	15771634	16	-	28162770	MONOMAC1	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.08908117188728137	[154]	[188]	0	hSpCas9	negative selection	12059461
15763817	15763840	16	-	28162770	MONOMAC1	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	0.8973787548325527	[206]	[441]	8	hSpCas9	negative selection	12059462
15759614	15759637	16	+	28162770	MONOMAC1	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.28101044974509043	[83]	[116]	3	hSpCas9	negative selection	12059463
15756486	15756509	16	+	28162770	MONOMAC1	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	0.2724484362416665	[155]	[215]	2	hSpCas9	negative selection	12059464
15745159	15745182	16	-	28162770	OCIAML2	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.5838179587802153	[77]	[647]	5	hSpCas9	negative selection	12228822
15724733	15724756	16	-	28162770	OCIAML2	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	-0.03767041796605497	[4]	[26]	0	hSpCas9	negative selection	12228823
15720952	15720975	16	-	28162770	OCIAML2	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.5329724114380345	[49]	[400]	5	hSpCas9	negative selection	12228824
15838096	15838119	16	-	28162770	OCIAML2	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	0.7281500388723363	[32]	[302]	7	hSpCas9	negative selection	12228825
15838042	15838065	16	-	28162770	OCIAML2	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-0.5003771686362131	[48]	[191]	-4	hSpCas9	negative selection	12228826
15771611	15771634	16	-	28162770	OCIAML2	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.0337142152707105	[45]	[260]	0	hSpCas9	negative selection	12228827
15763817	15763840	16	-	28162770	OCIAML2	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	0.08736562787872554	[44]	[264]	0	hSpCas9	negative selection	12228828
15759614	15759637	16	+	28162770	OCIAML2	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	0.9023222726696678	[24]	[258]	8	hSpCas9	negative selection	12228829
15756486	15756509	16	+	28162770	OCIAML2	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	0.36587144247495945	[34]	[249]	3	hSpCas9	negative selection	12228830
15745159	15745182	16	-	28162770	OCIAML3	viability	GCGCCGCCTACCTCAAGCTGCGG	MYH11	ENSG00000133392	0.194096802833844	[96]	[334]	1	hSpCas9	negative selection	12398188
15724733	15724756	16	-	28162770	OCIAML3	viability	GAAGCTGCGCCAGCTGGAGGAGG	MYH11	ENSG00000133392	0.28046147759197826	[11]	[43]	2	hSpCas9	negative selection	12398189
15720952	15720975	16	-	28162770	OCIAML3	viability	GGACGAGCTGCAAGCCACGGAGG	MYH11	ENSG00000133392	0.38737668150849003	[77]	[307]	3	hSpCas9	negative selection	12398190
15838096	15838119	16	-	28162770	OCIAML3	viability	CGAGGCAGCCAGCATTAAGGAGG	MYH11	ENSG00000133392	0.5552183684503132	[38]	[172]	5	hSpCas9	negative selection	12398191
15838042	15838065	16	-	28162770	OCIAML3	viability	GGAGAATGGCAAGAAGGTCACGG	MYH11	ENSG00000133392	-0.03458023171014457	[75]	[223]	0	hSpCas9	negative selection	12398192
15771611	15771634	16	-	28162770	OCIAML3	viability	TGAGATGTTCCAGGAAACCGTGG	MYH11	ENSG00000133392	0.09331657802667082	[67]	[218]	0	hSpCas9	negative selection	12398193
15763817	15763840	16	-	28162770	OCIAML3	viability	GAAGGAAAGAAACACAGACCAGG	MYH11	ENSG00000133392	0.6406536183455488	[91]	[432]	6	hSpCas9	negative selection	12398194
15759614	15759637	16	+	28162770	OCIAML3	viability	GGAAGGAAGCCCCTTGCCGATGG	MYH11	ENSG00000133392	-0.03107144593300598	[43]	[129]	0	hSpCas9	negative selection	12398195
15756486	15756509	16	+	28162770	OCIAML3	viability	AGCAGGGCCAGCACACCTGGAGG	MYH11	ENSG00000133392	-0.4451442544096803	[68]	[152]	-3	hSpCas9	negative selection	12398196