| 10319052 | 10319075 | 17 | - | 26472758 | Jiyoye | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -1.9464615731088268 | [91] | [17] | -8 | hSpCas9 | negative selection | 104439 | 10345234 | 10345257 | 17 | - | 26472758 | Jiyoye | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | -1.9978084531090474 | [142] | [26] | -8 | hSpCas9 | negative selection | 104440 | 10319158 | 10319181 | 17 | - | 26472758 | Jiyoye | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 5.162062883669342 | [0] | [26] | 9 | hSpCas9 | negative selection | 104441 | 10319092 | 10319115 | 17 | - | 26472758 | Jiyoye | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.44194079966655 | [81] | [83] | 3 | hSpCas9 | negative selection | 104442 | 10319052 | 10319075 | 17 | - | 26472758 | KBM7 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -1.9423894484854087 | [416,283] | [27,54] | -8 | hSpCas9 | negative selection | 295557 | 10345234 | 10345257 | 17 | - | 26472758 | KBM7 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | -0.060386100776381846 | [192,286] | [121,100] | 0 | hSpCas9 | negative selection | 295558 | 10319158 | 10319181 | 17 | - | 26472758 | KBM7 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 0.5850791127556088 | [173,236] | [205,95] | 6 | hSpCas9 | negative selection | 295559 | 10319092 | 10319115 | 17 | - | 26472758 | KBM7 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.8005765022069278 | [360,249] | [288,208] | 8 | hSpCas9 | negative selection | 295560 | 10319052 | 10319075 | 17 | - | 26472758 | Raji | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -1.51059402257552 | [220] | [17] | -8 | hSpCas9 | negative selection | 486675 | 10345234 | 10345257 | 17 | - | 26472758 | Raji | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | 0.5889164464393501 | [105] | [36] | 5 | hSpCas9 | negative selection | 486676 | 10319158 | 10319181 | 17 | - | 26472758 | Raji | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | -0.5282050384175248 | [86] | [13] | -4 | hSpCas9 | negative selection | 486677 | 10319092 | 10319115 | 17 | - | 26472758 | Raji | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.36820011595757474 | [216] | [64] | 3 | hSpCas9 | negative selection | 486678 | 10319052 | 10319075 | 17 | - | 26472758 | K562 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -3.2673339261009327 | [364] | [31] | -8 | hSpCas9 | negative selection | 677793 | 10345234 | 10345257 | 17 | - | 26472758 | K562 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | 0.2777388008664734 | [213] | [218] | 2 | hSpCas9 | negative selection | 677794 | 10319158 | 10319181 | 17 | - | 26472758 | K562 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 0.7198920808072647 | [186] | [259] | 6 | hSpCas9 | negative selection | 677795 | 10319092 | 10319115 | 17 | - | 26472758 | K562 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.48849204441584576 | [216] | [256] | 4 | hSpCas9 | negative selection | 677796 | 10346721 | 10346744 | 17 | + | 26627737 | DLD1 | viability | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | -0.02954854505697946 | [1536] | [339,454,596] | 0 | hSpCas9 | negative selection | 796051 | 10354725 | 10354748 | 17 | + | 26627737 | DLD1 | viability | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.7177044110378503 | [313] | [134,98,235] | 7 | hSpCas9 | negative selection | 796052 | 10362479 | 10362502 | 17 | - | 26627737 | DLD1 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.442430880646966 | [234] | [59,30,67] | -4 | hSpCas9 | negative selection | 796053 | 10364509 | 10364532 | 17 | - | 26627737 | DLD1 | viability | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.40993819709282153 | [747] | [362,403,187] | 4 | hSpCas9 | negative selection | 796054 | 10346721 | 10346744 | 17 | + | 26627737 | GBM cells | viability after 5 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.5058070156763442 | [456] | [352,342] | 7 | hSpCas9 | negative selection | 878366 | 10354725 | 10354748 | 17 | + | 26627737 | GBM cells | viability after 5 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.4052665409104753 | [175] | [146,102] | 6 | hSpCas9 | negative selection | 878367 | 10362479 | 10362502 | 17 | - | 26627737 | GBM cells | viability after 5 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.19419552950579577 | [111] | [42,61] | -3 | hSpCas9 | negative selection | 878368 | 10364509 | 10364532 | 17 | - | 26627737 | GBM cells | viability after 5 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | -0.03461184722629973 | [614] | [307,335] | 0 | hSpCas9 | negative selection | 878369 | 10346721 | 10346744 | 17 | + | 26627737 | GBM cells | viability after 13 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.1601778459078781 | [456] | [286,268] | 2 | hSpCas9 | negative selection | 960681 | 10354725 | 10354748 | 17 | + | 26627737 | GBM cells | viability after 13 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.3830994002946454 | [175] | [166,89] | 5 | hSpCas9 | negative selection | 960682 | 10362479 | 10362502 | 17 | - | 26627737 | GBM cells | viability after 13 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.3688283114550891 | [111] | [51,99] | 5 | hSpCas9 | negative selection | 960683 | 10364509 | 10364532 | 17 | - | 26627737 | GBM cells | viability after 13 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | -0.010658908430951408 | [614] | [376,293] | 0 | hSpCas9 | negative selection | 960684 | 10346721 | 10346744 | 17 | + | 26627737 | GBM cells | viability after 21 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.6518009465810094 | [456] | [399,380] | 6 | hSpCas9 | negative selection | 1042996 | 10354725 | 10354748 | 17 | + | 26627737 | GBM cells | viability after 21 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.9077484051500295 | [175] | [181,176] | 8 | hSpCas9 | negative selection | 1042997 | 10362479 | 10362502 | 17 | - | 26627737 | GBM cells | viability after 21 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.3034059163921812 | [111] | [72,76] | 3 | hSpCas9 | negative selection | 1042998 | 10364509 | 10364532 | 17 | - | 26627737 | GBM cells | viability after 21 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.38305558302792897 | [614] | [453,418] | 4 | hSpCas9 | negative selection | 1042999 | 10346721 | 10346744 | 17 | + | 26627737 | RPE1 | viability after 9 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.737600947070769 | [2020] | [1326,703] | 5 | hSpCas9 | negative selection | 1125311 | 10354725 | 10354748 | 17 | + | 26627737 | RPE1 | viability after 9 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | -1.143910915554304 | [1070] | [204,82] | -7 | hSpCas9 | negative selection | 1125312 | 10362479 | 10362502 | 17 | - | 26627737 | RPE1 | viability after 9 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 6.2351662058530115 | [8] | [244,169] | 9 | hSpCas9 | negative selection | 1125313 | 10364509 | 10364532 | 17 | - | 26627737 | RPE1 | viability after 9 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 2.209179941290629 | [714] | [1014,1060] | 9 | hSpCas9 | negative selection | 1125314 | 10346721 | 10346744 | 17 | + | 26627737 | RPE1 | viability after 12 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.8388824166617224 | [2020] | [1266,657] | 5 | hSpCas9 | negative selection | 1207626 | 10354725 | 10354748 | 17 | + | 26627737 | RPE1 | viability after 12 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | -0.7214300232252333 | [1070] | [191,155] | -5 | hSpCas9 | negative selection | 1207627 | 10362479 | 10362502 | 17 | - | 26627737 | RPE1 | viability after 12 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 5.922770973861277 | [8] | [152,139] | 9 | hSpCas9 | negative selection | 1207628 | 10364509 | 10364532 | 17 | - | 26627737 | RPE1 | viability after 12 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 2.596883688509672 | [714] | [1370,940] | 9 | hSpCas9 | negative selection | 1207629 | 10346721 | 10346744 | 17 | + | 26627737 | RPE1 | viability after 15 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 1.4289654339273437 | [2020] | [2027,1067] | 7 | hSpCas9 | negative selection | 1289941 | 10354725 | 10354748 | 17 | + | 26627737 | RPE1 | viability after 15 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | -0.7910928378227926 | [1070] | [85,260] | -5 | hSpCas9 | negative selection | 1289942 | 10362479 | 10362502 | 17 | - | 26627737 | RPE1 | viability after 15 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 6.528785212287937 | [8] | [230,238] | 9 | hSpCas9 | negative selection | 1289943 | 10364509 | 10364532 | 17 | - | 26627737 | RPE1 | viability after 15 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 2.4076028069793955 | [714] | [1288,864] | 9 | hSpCas9 | negative selection | 1289944 | 10346721 | 10346744 | 17 | + | 26627737 | RPE1 | viability after 18 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 1.3358096743942212 | [2020] | [1600,1136] | 7 | hSpCas9 | negative selection | 1372256 | 10354725 | 10354748 | 17 | + | 26627737 | RPE1 | viability after 18 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | -0.8899352873449871 | [1070] | [125,187] | -5 | hSpCas9 | negative selection | 1372257 | 10362479 | 10362502 | 17 | - | 26627737 | RPE1 | viability after 18 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 6.989922316670298 | [8] | [358,254] | 9 | hSpCas9 | negative selection | 1372258 | 10364509 | 10364532 | 17 | - | 26627737 | RPE1 | viability after 18 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 2.4238915232612768 | [714] | [1120,943] | 9 | hSpCas9 | negative selection | 1372259 | 10346721 | 10346744 | 17 | + | 26627737 | HeLa | viability after 8 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.38439956829262456 | [741] | [620,424,272] | 3 | hSpCas9 | negative selection | 1454571 | 10354725 | 10354748 | 17 | + | 26627737 | HeLa | viability after 8 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.03218649009210191 | [360] | [87,203,172] | 0 | hSpCas9 | negative selection | 1454572 | 10362479 | 10362502 | 17 | - | 26627737 | HeLa | viability after 8 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.028388698828528902 | [191] | [88,119,49] | 0 | hSpCas9 | negative selection | 1454573 | 10364509 | 10364532 | 17 | - | 26627737 | HeLa | viability after 8 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.36495016615511666 | [785] | [391,363,546] | 3 | hSpCas9 | negative selection | 1454574 | 10346721 | 10346744 | 17 | + | 26627737 | HeLa | viability after 12 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.9647669759245753 | [741] | [772,546,485] | 7 | hSpCas9 | negative selection | 1536886 | 10354725 | 10354748 | 17 | + | 26627737 | HeLa | viability after 12 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.1681205719512594 | [360] | [154,247,90] | 1 | hSpCas9 | negative selection | 1536887 | 10362479 | 10362502 | 17 | - | 26627737 | HeLa | viability after 12 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.0702451304628362 | [191] | [120,73,56] | 0 | hSpCas9 | negative selection | 1536888 | 10364509 | 10364532 | 17 | - | 26627737 | HeLa | viability after 12 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.5513629789798205 | [785] | [449,327,664] | 4 | hSpCas9 | negative selection | 1536889 | 10346721 | 10346744 | 17 | + | 26627737 | HeLa | viability after 15 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.22930828611030452 | [741] | [211,342,521] | 2 | hSpCas9 | negative selection | 1619201 | 10354725 | 10354748 | 17 | + | 26627737 | HeLa | viability after 15 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.149383361564675 | [360] | [176,218,86] | 1 | hSpCas9 | negative selection | 1619202 | 10362479 | 10362502 | 17 | - | 26627737 | HeLa | viability after 15 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.03830240283625164 | [191] | [142,76,14] | 0 | hSpCas9 | negative selection | 1619203 | 10364509 | 10364532 | 17 | - | 26627737 | HeLa | viability after 15 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.7002731906144697 | [785] | [516,338,718] | 5 | hSpCas9 | negative selection | 1619204 | 10346721 | 10346744 | 17 | + | 26627737 | HeLa | viability after 18 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.19313587986259184 | [741] | [133,272,521] | 1 | hSpCas9 | negative selection | 1701516 | 10354725 | 10354748 | 17 | + | 26627737 | HeLa | viability after 18 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.1401103524050782 | [360] | [116,180,86] | 1 | hSpCas9 | negative selection | 1701517 | 10362479 | 10362502 | 17 | - | 26627737 | HeLa | viability after 18 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.14894647281628448 | [191] | [104,67,14] | 1 | hSpCas9 | negative selection | 1701518 | 10364509 | 10364532 | 17 | - | 26627737 | HeLa | viability after 18 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.7016266015680621 | [785] | [345,282,718] | 5 | hSpCas9 | negative selection | 1701519 | 10346721 | 10346744 | 17 | + | 26627737 | HCT116 | viability after 6 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 1.3466378100151823 | [1112] | [531,396] | 7 | hSpCas9 | negative selection | 1783831 | 10354725 | 10354748 | 17 | + | 26627737 | HCT116 | viability after 6 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.6841195762151003 | [205] | [120,13] | 4 | hSpCas9 | negative selection | 1783832 | 10362479 | 10362502 | 17 | - | 26627737 | HCT116 | viability after 6 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.22256923303357334 | [139] | [43,4] | -1 | hSpCas9 | negative selection | 1783833 | 10364509 | 10364532 | 17 | - | 26627737 | HCT116 | viability after 6 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 1.8899134099059238 | [938] | [1083,250] | 8 | hSpCas9 | negative selection | 1783834 | 10346721 | 10346744 | 17 | + | 26627737 | HCT116 | viability after 8 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.04845827764743771 | [540] | [225,273,421] | 0 | hSpCas9 | negative selection | 1866146 | 10354725 | 10354748 | 17 | + | 26627737 | HCT116 | viability after 8 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.7074040430979264 | [100] | [100,96,74] | 6 | hSpCas9 | negative selection | 1866147 | 10362479 | 10362502 | 17 | - | 26627737 | HCT116 | viability after 8 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 1.2545632350648126 | [42] | [79,31,57] | 8 | hSpCas9 | negative selection | 1866148 | 10364509 | 10364532 | 17 | - | 26627737 | HCT116 | viability after 8 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.16482145923125646 | [649] | [438,346,418] | 2 | hSpCas9 | negative selection | 1866149 | 10346721 | 10346744 | 17 | + | 26627737 | HCT116 | viability after 9 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 1.156459911984514 | [1112] | [657,665] | 7 | hSpCas9 | negative selection | 1948461 | 10354725 | 10354748 | 17 | + | 26627737 | HCT116 | viability after 9 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | -0.2556901369382072 | [205] | [73,23] | -2 | hSpCas9 | negative selection | 1948462 | 10362479 | 10362502 | 17 | - | 26627737 | HCT116 | viability after 9 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 1.2505637399039014 | [139] | [98,80] | 8 | hSpCas9 | negative selection | 1948463 | 10364509 | 10364532 | 17 | - | 26627737 | HCT116 | viability after 9 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.9770069143079864 | [938] | [621,391] | 6 | hSpCas9 | negative selection | 1948464 | 10346721 | 10346744 | 17 | + | 26627737 | HCT116 | viability after 12 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.27694243757207626 | [540] | [134,268,645] | 3 | hSpCas9 | negative selection | 2030776 | 10354725 | 10354748 | 17 | + | 26627737 | HCT116 | viability after 12 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 1.148001881794118 | [100] | [142,90,115] | 8 | hSpCas9 | negative selection | 2030777 | 10362479 | 10362502 | 17 | - | 26627737 | HCT116 | viability after 12 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 1.2683666579452664 | [42] | [59,61,40] | 8 | hSpCas9 | negative selection | 2030778 | 10364509 | 10364532 | 17 | - | 26627737 | HCT116 | viability after 12 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.4215247924561871 | [649] | [503,562,303] | 4 | hSpCas9 | negative selection | 2030779 | 10346721 | 10346744 | 17 | + | 26627737 | HCT116 | viability after 15 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.41088985903973485 | [540] | [236,419,558] | 4 | hSpCas9 | negative selection | 2113091 | 10354725 | 10354748 | 17 | + | 26627737 | HCT116 | viability after 15 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 1.0313621306630574 | [100] | [165,122,72] | 8 | hSpCas9 | negative selection | 2113092 | 10362479 | 10362502 | 17 | - | 26627737 | HCT116 | viability after 15 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 1.5793626834763435 | [42] | [115,75,34] | 9 | hSpCas9 | negative selection | 2113093 | 10364509 | 10364532 | 17 | - | 26627737 | HCT116 | viability after 15 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.1387733656134149 | [649] | [448,495,293] | 1 | hSpCas9 | negative selection | 2113094 | 10346721 | 10346744 | 17 | + | 26627737 | HCT116 | viability after 18 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.5148404067832894 | [540] | [88,465,568] | 4 | hSpCas9 | negative selection | 2195406 | 10354725 | 10354748 | 17 | + | 26627737 | HCT116 | viability after 18 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.6942422265585275 | [100] | [76,79,79] | 5 | hSpCas9 | negative selection | 2195407 | 10362479 | 10362502 | 17 | - | 26627737 | HCT116 | viability after 18 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 2.035276123223829 | [42] | [128,46,81] | 9 | hSpCas9 | negative selection | 2195408 | 10364509 | 10364532 | 17 | - | 26627737 | HCT116 | viability after 18 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.4755020995436525 | [649] | [297,688,300] | 4 | hSpCas9 | negative selection | 2195409 | 10373119 | 10373142 | 17 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TTAACAAGAGTGAGAGATCAGGG | MYH13 | ENSG00000006788 | -1.0427968276978052 | [482,64] | [45,9] | -6 | dCas9-VP64 | positive selection | 2433830 | 10373119 | 10373142 | 17 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TTAACAAGAGTGAGAGATCAGGG | MYH13 | ENSG00000006788 | -0.10224298980632529 | [112,253] | [59,49] | -1 | dCas9-VP64 | positive selection | 2529085 | 10346744 | 10346767 | 17 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | AATTCTGCAGAAATGCTGAAGGG | MYH13 | ENSG00000006788 | 0.04295189264303256 | [1,1] | [2,0] | 0 | hSpCas9 | positive selection | 3004140 | 10357815 | 10357838 | 17 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TTATTATTAGGGAACCCTAGAGG | MYH13 | ENSG00000006788 | 0.11106599742110398 | [3,3] | [4,2] | 2 | hSpCas9 | positive selection | 3004141 | 10346744 | 10346767 | 17 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | AATTCTGCAGAAATGCTGAAGGG | MYH13 | ENSG00000006788 | -0.22527780059054192 | [1,1] | [0,0] | -3 | hSpCas9 | positive selection | 3071998 | 10357815 | 10357838 | 17 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TTATTATTAGGGAACCCTAGAGG | MYH13 | ENSG00000006788 | 0.36760307037196854 | [3,3] | [4,2] | 6 | hSpCas9 | positive selection | 3071999 | 10362438 | 10362461 | 17 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 1.923425474892397 | [120,120] | [2,2] | 7 | hSpCas9 | positive selection | 3380614 | 10360004 | 10360027 | 17 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | -0.537089654904271 | [221,221] | [0,0] | -4 | hSpCas9 | positive selection | 3380615 | 10362230 | 10362253 | 17 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TCACCGTCAACCCCTACAAGTGG | MYH13 | ENSG00000006788 | 1.4759664979211755 | [54,54] | [0,0] | 6 | hSpCas9 | positive selection | 3380616 | 10346744 | 10346767 | 17 | - | 26780180 | HT29 | viability (Avana library 4 designs) | AATTCTGCAGAAATGCTGAAGGG | MYH13 | ENSG00000006788 | 1.59773347350047 | [] | [] | 6 | hSpCas9 | negative selection | 3441946 | 10357815 | 10357838 | 17 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TTATTATTAGGGAACCCTAGAGG | MYH13 | ENSG00000006788 | 1.17113502101596 | [] | [] | 4 | hSpCas9 | negative selection | 3441947 | 10357815 | 10357838 | 17 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TTATTATTAGGGAACCCTAGAGG | MYH13 | ENSG00000006788 | -11.2953307883447 | [] | [] | -8 | hSpCas9 | negative selection | 3532906 | 10346744 | 10346767 | 17 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AATTCTGCAGAAATGCTGAAGGG | MYH13 | ENSG00000006788 | -3.38408708669526 | [] | [] | -4 | hSpCas9 | negative selection | 3532907 | 10364461 | 10364484 | 17 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TCTCCTTCTCTGGTTTCCGGAGG | MYH13 | ENSG00000006788 | -7.46001398823993 | [] | [] | -6 | hSpCas9 | negative selection | 3532908 | 10357815 | 10357838 | 17 | - | 26780180 | A375 | viability (Avana lentiGuide) | TTATTATTAGGGAACCCTAGAGG | MYH13 | ENSG00000006788 | -6.86908093842032 | [] | [] | -9 | hSpCas9 | negative selection | 3641565 | 10346744 | 10346767 | 17 | - | 26780180 | A375 | viability (Avana lentiGuide) | AATTCTGCAGAAATGCTGAAGGG | MYH13 | ENSG00000006788 | -4.85069399085834 | [] | [] | -8 | hSpCas9 | negative selection | 3641566 | 10364461 | 10364484 | 17 | + | 26780180 | A375 | viability (Avana lentiGuide) | TCTCCTTCTCTGGTTTCCGGAGG | MYH13 | ENSG00000006788 | 0.238578569830584 | [] | [] | 0 | hSpCas9 | negative selection | 3641567 | 10357815 | 10357838 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TTATTATTAGGGAACCCTAGAGG | MYH13 | ENSG00000006788 | -0.7837176036774305 | [8] | [4,3] | -8 | hSpCas9 | positive selection | 3750224 | 10346744 | 10346767 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AATTCTGCAGAAATGCTGAAGGG | MYH13 | ENSG00000006788 | -0.38859930380333024 | [4] | [4,2] | -5 | hSpCas9 | positive selection | 3750225 | 10364461 | 10364484 | 17 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TCTCCTTCTCTGGTTTCCGGAGG | MYH13 | ENSG00000006788 | -1.057016584957806 | [1] | [0,0] | -9 | hSpCas9 | positive selection | 3750226 | 10357815 | 10357838 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TTATTATTAGGGAACCCTAGAGG | MYH13 | ENSG00000006788 | -0.10455625767039144 | [5] | [4,3] | -1 | hSpCas9 | positive selection | 3858831 | 10346744 | 10346767 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AATTCTGCAGAAATGCTGAAGGG | MYH13 | ENSG00000006788 | 0.32003237333743734 | [2] | [4,1] | 8 | hSpCas9 | positive selection | 3858832 | 10364461 | 10364484 | 17 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TCTCCTTCTCTGGTTTCCGGAGG | MYH13 | ENSG00000006788 | 0.2529719287404856 | [2] | [1,3] | 6 | hSpCas9 | positive selection | 3858833 | 10360156 | 10360179 | 17 | + | 26780180 | A375 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 1.48088096958457 | [] | [] | 8 | hSpCas9 | negative selection | 3970149 | 10360004 | 10360027 | 17 | + | 26780180 | A375 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 1.12194405015249 | [] | [] | 5 | hSpCas9 | negative selection | 3970150 | 10362479 | 10362502 | 17 | - | 26780180 | A375 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 1.91677207760013 | [] | [] | 9 | hSpCas9 | negative selection | 3970151 | 10362438 | 10362461 | 17 | + | 26780180 | A375 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.313618981317722 | [] | [] | 0 | hSpCas9 | negative selection | 3970152 | 10360060 | 10360083 | 17 | - | 26780180 | A375 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 1.28863205754117 | [] | [] | 7 | hSpCas9 | negative selection | 3970153 | 10360156 | 10360179 | 17 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 1.07148370766885 | [] | [] | 5 | hSpCas9 | negative selection | 4078115 | 10360004 | 10360027 | 17 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 1.80393989370433 | [] | [] | 8 | hSpCas9 | negative selection | 4078116 | 10362479 | 10362502 | 17 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 1.80511926034448 | [] | [] | 8 | hSpCas9 | negative selection | 4078117 | 10362438 | 10362461 | 17 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.934492646589456 | [] | [] | 4 | hSpCas9 | negative selection | 4078118 | 10360060 | 10360083 | 17 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 1.64997779580092 | [] | [] | 8 | hSpCas9 | negative selection | 4078119 | 10360060 | 10360083 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.14623434853778594 | [1] | [1,1] | 3 | hSpCas9 | positive selection | 4284368 | 10362479 | 10362502 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.07536104620019063 | [3] | [2,2] | -1 | hSpCas9 | positive selection | 4284369 | 10360156 | 10360179 | 17 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | -0.3360512558730331 | [3] | [3,0] | -6 | hSpCas9 | positive selection | 4284370 | 10362438 | 10362461 | 17 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.6699673699854982 | [1] | [2,2] | 9 | hSpCas9 | positive selection | 4348626 | 10360004 | 10360027 | 17 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | -0.09959993909051187 | [3] | [2,1] | -2 | hSpCas9 | positive selection | 4348627 | 10350550 | 10350572 | 17 | + | 27760321 | OCIAML3 | viability | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | -0.0038077588588251166 | [823,831] | [550,774] | 0 | hSpCas9 | negative selection | 4420490 | 10350634 | 10350656 | 17 | - | 27760321 | OCIAML3 | viability | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 0.6821931359300253 | [434,313] | [420,522] | 7 | hSpCas9 | negative selection | 4420491 | 10350550 | 10350572 | 17 | + | 27760321 | OCIAML2 | viability | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | 0.27481948573054826 | [823,831] | [739,909] | 3 | hSpCas9 | negative selection | 4503953 | 10350634 | 10350656 | 17 | - | 27760321 | OCIAML2 | viability | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 0.4356841871962777 | [434,313] | [327,507] | 6 | hSpCas9 | negative selection | 4503954 | 10350550 | 10350572 | 17 | + | 27760321 | MV411 | viability | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | 0.12470104004017701 | [823,831] | [501,741] | 0 | hSpCas9 | negative selection | 4587416 | 10350634 | 10350656 | 17 | - | 27760321 | MV411 | viability | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 0.41441046026665257 | [434,313] | [423,178] | 3 | hSpCas9 | negative selection | 4587417 | 10350550 | 10350572 | 17 | + | 27760321 | HL60 | viability | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | 0.2622473255068286 | [823,831] | [803,824] | 3 | hSpCas9 | negative selection | 4670879 | 10350634 | 10350656 | 17 | - | 27760321 | HL60 | viability | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 0.11546459706491582 | [434,313] | [314,341] | 1 | hSpCas9 | negative selection | 4670880 | 10350550 | 10350572 | 17 | + | 27760321 | HT1080 | viability | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | -0.39942721507651835 | [831,648] | [173,277] | -2 | hSpCas9 | negative selection | 4754342 | 10350634 | 10350656 | 17 | - | 27760321 | HT1080 | viability | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 0.2624535588991738 | [313,244] | [197,62] | 1 | hSpCas9 | negative selection | 4754343 | 10350550 | 10350572 | 17 | + | 27760321 | HT29 | viability after 7 days | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | -0.5644749881297535 | [831,648] | [732,594,615] | -7 | hSpCas9 | negative selection | 4837805 | 10350634 | 10350656 | 17 | - | 27760321 | HT29 | viability after 7 days | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 0.2142303459065288 | [313,244] | [614,332,332] | 3 | hSpCas9 | negative selection | 4837806 | 10350550 | 10350572 | 17 | + | 27760321 | HT29 | viability after 25 days | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | -0.18107655526070365 | [831,648] | [451,882,941] | -2 | hSpCas9 | negative selection | 4921268 | 10350634 | 10350656 | 17 | - | 27760321 | HT29 | viability after 25 days | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 1.0836205963883998 | [313,244] | [806,680,516] | 9 | hSpCas9 | negative selection | 4921269 | 10350550 | 10350572 | 17 | + | 27760321 | HT29 | viability after 22 days | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | -0.16691274914379317 | [831,648] | [843,602,838] | -2 | hSpCas9 | negative selection | 5004731 | 10350634 | 10350656 | 17 | - | 27760321 | HT29 | viability after 22 days | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 0.6410151928368266 | [313,244] | [493,497,519] | 7 | hSpCas9 | negative selection | 5004732 | 10350550 | 10350572 | 17 | + | 27760321 | HT29 | viability after 19 days | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | -0.5682749641532405 | [831,648] | [410,786,500] | -5 | hSpCas9 | negative selection | 5088194 | 10350634 | 10350656 | 17 | - | 27760321 | HT29 | viability after 19 days | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 0.7698246536019691 | [313,244] | [591,592,457] | 7 | hSpCas9 | negative selection | 5088195 | 10350550 | 10350572 | 17 | + | 27760321 | HT29 | viability after 16 days | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | -0.4663355220453417 | [831,648] | [545,550,697] | -5 | hSpCas9 | negative selection | 5171657 | 10350634 | 10350656 | 17 | - | 27760321 | HT29 | viability after 16 days | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 0.5261525809626352 | [313,244] | [442,418,488] | 6 | hSpCas9 | negative selection | 5171658 | 10350550 | 10350572 | 17 | + | 27760321 | HT29 | viability after 13 days | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | -0.41870257734520655 | [831,648] | [644,728,558] | -5 | hSpCas9 | negative selection | 5255120 | 10350634 | 10350656 | 17 | - | 27760321 | HT29 | viability after 13 days | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 0.7423245651965507 | [313,244] | [516,478,625] | 8 | hSpCas9 | negative selection | 5255121 | 10350550 | 10350572 | 17 | + | 27760321 | HT29 | viability after 10 days | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | -0.5426320226140187 | [831,648] | [663,821,427] | -6 | hSpCas9 | negative selection | 5338583 | 10350634 | 10350656 | 17 | - | 27760321 | HT29 | viability after 10 days | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 0.8334923728428145 | [313,244] | [1025,511,330] | 9 | hSpCas9 | negative selection | 5338584 | 10350550 | 10350572 | 17 | + | 27760321 | MOLM13 | viability | AGTTACCTTCGGTGCCGTCTGG | MYH13 | ENSG00000006788 | 0.48574063627534614 | [823,831] | [574,725] | 3 | hSpCas9 | negative selection | 5422046 | 10350634 | 10350656 | 17 | - | 27760321 | MOLM13 | viability | GTCGGGATCTACAAACTGACGG | MYH13 | ENSG00000006788 | 1.8295451038331012 | [434,313] | [245,1166] | 9 | hSpCas9 | negative selection | 5422047 | 10372515 | 10372538 | 17 | + | 27661255 | K562 | viability | GTAAGATGGGTAAGATGCTTGGG | MYH13 | ENSG00000006788 | 0.09527987168501961 | [2163,2388] | [2139,1767] | 3 | dCas9-KRAB | negative selection | 5495028 | 10372987 | 10373010 | 17 | + | 27661255 | K562 | viability | GCTGCGGTCACAGCAATTTCAGG | MYH13 | ENSG00000006788 | 0.1555413864984027 | [552,664] | [633,459] | 5 | dCas9-KRAB | negative selection | 5495029 | 10372978 | 10373001 | 17 | - | 27661255 | K562 | viability | GCTGTGACCGCAGCATCTCTAGG | MYH13 | ENSG00000006788 | -0.019990893068910998 | [323,271] | [248,223] | -1 | dCas9-KRAB | negative selection | 5495030 | 10360060 | 10360083 | 17 | - | 27260156 | BXPC3 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.3587513641917669 | [196] | [225,158,285,412] | 7 | hSpCas9 | negative selection | 5556828 | 10362479 | 10362502 | 17 | - | 27260156 | BXPC3 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.030501154933287422 | [733] | [687,701,806,971] | 0 | hSpCas9 | negative selection | 5556829 | 10360156 | 10360179 | 17 | + | 27260156 | BXPC3 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.05467253837528141 | [657] | [550,748,696,893] | 1 | hSpCas9 | negative selection | 5556830 | 10362438 | 10362461 | 17 | + | 27260156 | BXPC3 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.5791378510654965 | [149] | [150,277,286,225] | 9 | hSpCas9 | negative selection | 5621086 | 10360004 | 10360027 | 17 | + | 27260156 | BXPC3 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.17759762544566127 | [516] | [596,515,663,680] | 4 | hSpCas9 | negative selection | 5621087 | 10360060 | 10360083 | 17 | - | 27260156 | A673 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | -5.938281156536718e-05 | [196] | [209,277,270,178] | 0 | hSpCas9 | negative selection | 5678079 | 10362479 | 10362502 | 17 | - | 27260156 | A673 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.026102158673139475 | [733] | [883,827,802,953] | 0 | hSpCas9 | negative selection | 5678080 | 10360156 | 10360179 | 17 | + | 27260156 | A673 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.11167227392105317 | [657] | [892,628,806,1108] | 2 | hSpCas9 | negative selection | 5678081 | 10362438 | 10362461 | 17 | + | 27260156 | A673 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.34118438435746823 | [149] | [239,157,300,214] | 7 | hSpCas9 | negative selection | 5742337 | 10360004 | 10360027 | 17 | + | 27260156 | A673 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.14870153540704517 | [516] | [654,719,649,723] | 3 | hSpCas9 | negative selection | 5742338 | 10360060 | 10360083 | 17 | - | 27260156 | A375 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | -0.013629103395544906 | [196] | [335,183,235,157] | 0 | hSpCas9 | negative selection | 5799330 | 10362479 | 10362502 | 17 | - | 27260156 | A375 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.13105108213738526 | [733] | [839,943,757,627] | -2 | hSpCas9 | negative selection | 5799331 | 10360156 | 10360179 | 17 | + | 27260156 | A375 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | -0.03992370444579513 | [657] | [852,771,752,627] | 0 | hSpCas9 | negative selection | 5799332 | 10362438 | 10362461 | 17 | + | 27260156 | A375 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.5390092525854027 | [149] | [276,306,345,111] | 7 | hSpCas9 | negative selection | 5863588 | 10360004 | 10360027 | 17 | + | 27260156 | A375 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.5373115363559 | [516] | [929,1005,916,689] | 7 | hSpCas9 | negative selection | 5863589 | 10360060 | 10360083 | 17 | - | 27260156 | COLO741 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.1211076635062942 | [196] | [276,368,181] | 2 | hSpCas9 | negative selection | 5920581 | 10362479 | 10362502 | 17 | - | 27260156 | COLO741 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.06060746995526056 | [733] | [809,987,890] | -1 | hSpCas9 | negative selection | 5920582 | 10360156 | 10360179 | 17 | + | 27260156 | COLO741 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.038990255473203006 | [657] | [923,801,867] | 0 | hSpCas9 | negative selection | 5920583 | 10362438 | 10362461 | 17 | + | 27260156 | COLO741 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.4625298424970863 | [149] | [301,272,222] | 8 | hSpCas9 | negative selection | 5984839 | 10360004 | 10360027 | 17 | + | 27260156 | COLO741 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.2759086814545694 | [516] | [748,880,765] | 6 | hSpCas9 | negative selection | 5984840 | 10360060 | 10360083 | 17 | - | 27260156 | CAL120 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 1.093082958032971 | [196] | [195,493,823] | 9 | hSpCas9 | negative selection | 6041832 | 10362479 | 10362502 | 17 | - | 27260156 | CAL120 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.2593109005216665 | [733] | [1240,884,1173] | 4 | hSpCas9 | negative selection | 6041833 | 10360156 | 10360179 | 17 | + | 27260156 | CAL120 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.12857507179741345 | [657] | [962,935,797] | 2 | hSpCas9 | negative selection | 6041834 | 10362438 | 10362461 | 17 | + | 27260156 | CAL120 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 1.0836742619655517 | [149] | [452,441,301] | 9 | hSpCas9 | negative selection | 6106090 | 10360004 | 10360027 | 17 | + | 27260156 | CAL120 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.5938883796595155 | [516] | [1178,909,856] | 8 | hSpCas9 | negative selection | 6106091 | 10360060 | 10360083 | 17 | - | 27260156 | CADOES1 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.4002413957750093 | [196] | [222,274,184,285] | 6 | hSpCas9 | negative selection | 6163083 | 10362479 | 10362502 | 17 | - | 27260156 | CADOES1 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.02999180861434947 | [733] | [502,812,516,848] | 0 | hSpCas9 | negative selection | 6163084 | 10360156 | 10360179 | 17 | + | 27260156 | CADOES1 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.33499014410418126 | [657] | [648,755,680,1010] | 5 | hSpCas9 | negative selection | 6163085 | 10362438 | 10362461 | 17 | + | 27260156 | CADOES1 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.6854763390981273 | [149] | [233,199,222,240] | 9 | hSpCas9 | negative selection | 6227341 | 10360004 | 10360027 | 17 | + | 27260156 | CADOES1 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.42477300857496303 | [516] | [611,446,735,791] | 7 | hSpCas9 | negative selection | 6227342 | 10360060 | 10360083 | 17 | - | 27260156 | EWS502 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.7591074763011498 | [196] | [284,319,469,346] | 9 | hSpCas9 | negative selection | 6284334 | 10362479 | 10362502 | 17 | - | 27260156 | EWS502 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.11156815770475403 | [733] | [720,654,716,789] | -2 | hSpCas9 | negative selection | 6284335 | 10360156 | 10360179 | 17 | + | 27260156 | EWS502 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | -0.13032383941080772 | [657] | [440,740,690,695] | -2 | hSpCas9 | negative selection | 6284336 | 10362438 | 10362461 | 17 | + | 27260156 | EWS502 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 1.0419518772430845 | [149] | [377,272,296,356] | 9 | hSpCas9 | negative selection | 6348592 | 10360004 | 10360027 | 17 | + | 27260156 | EWS502 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.26486394949959385 | [516] | [631,736,494,770] | 4 | hSpCas9 | negative selection | 6348593 | 10360060 | 10360083 | 17 | - | 27260156 | EW8 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.43200588372228343 | [196] | [288,133,194,253] | 7 | hSpCas9 | negative selection | 6405585 | 10362479 | 10362502 | 17 | - | 27260156 | EW8 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.14835137178727648 | [733] | [708,531,492,437] | -3 | hSpCas9 | negative selection | 6405586 | 10360156 | 10360179 | 17 | + | 27260156 | EW8 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.14557549257042324 | [657] | [769,623,489,510] | 2 | hSpCas9 | negative selection | 6405587 | 10362438 | 10362461 | 17 | + | 27260156 | EW8 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.7269375785982596 | [149] | [188,174,258,169] | 9 | hSpCas9 | negative selection | 6469843 | 10360004 | 10360027 | 17 | + | 27260156 | EW8 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.3980105183682936 | [516] | [673,547,482,526] | 7 | hSpCas9 | negative selection | 6469844 | 10360060 | 10360083 | 17 | - | 27260156 | CORL105 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.5601295268785191 | [196] | [361,337,521,167] | 8 | hSpCas9 | negative selection | 6526836 | 10362479 | 10362502 | 17 | - | 27260156 | CORL105 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.033964371696549756 | [733] | [982,921,885,731] | 0 | hSpCas9 | negative selection | 6526837 | 10360156 | 10360179 | 17 | + | 27260156 | CORL105 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.10020565667493309 | [657] | [764,793,864,882] | 1 | hSpCas9 | negative selection | 6526838 | 10362438 | 10362461 | 17 | + | 27260156 | CORL105 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.22720095928520778 | [149] | [228,111,239,248] | 4 | hSpCas9 | negative selection | 6591094 | 10360004 | 10360027 | 17 | + | 27260156 | CORL105 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.2726396039907397 | [516] | [790,569,967,637] | 5 | hSpCas9 | negative selection | 6591095 | 10360060 | 10360083 | 17 | - | 27260156 | HS294T | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 1.2266702332052757 | [196] | [103,99,91,475] | 9 | hSpCas9 | negative selection | 6648087 | 10362479 | 10362502 | 17 | - | 27260156 | HS294T | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.08510823093177089 | [733] | [238,176,288,549] | 1 | hSpCas9 | negative selection | 6648088 | 10360156 | 10360179 | 17 | + | 27260156 | HS294T | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.06258857159977183 | [657] | [224,325,210,308] | 0 | hSpCas9 | negative selection | 6648089 | 10362438 | 10362461 | 17 | + | 27260156 | HS294T | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.8498371105435978 | [149] | [113,77,149,69] | 9 | hSpCas9 | negative selection | 6712345 | 10360004 | 10360027 | 17 | + | 27260156 | HS294T | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.3084510847403081 | [516] | [314,228,213,220] | 4 | hSpCas9 | negative selection | 6712346 | 10360060 | 10360083 | 17 | - | 27260156 | HCC44 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.3479733221716763 | [196] | [248,222,221,427] | 5 | hSpCas9 | negative selection | 6769338 | 10362479 | 10362502 | 17 | - | 27260156 | HCC44 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.0018634369528675032 | [733] | [1010,1005,718,554] | 0 | hSpCas9 | negative selection | 6769339 | 10360156 | 10360179 | 17 | + | 27260156 | HCC44 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.3159894321329051 | [657] | [874,1001,880,916] | 5 | hSpCas9 | negative selection | 6769340 | 10362438 | 10362461 | 17 | + | 27260156 | HCC44 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.7441836746792986 | [149] | [319,301,284,229] | 9 | hSpCas9 | negative selection | 6833596 | 10360004 | 10360027 | 17 | + | 27260156 | HCC44 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.562182469980129 | [516] | [1140,610,1215,608] | 8 | hSpCas9 | negative selection | 6833597 | 10360060 | 10360083 | 17 | - | 27260156 | G402 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.664241413197732 | [196] | [219,519,404,362] | 7 | hSpCas9 | negative selection | 6890589 | 10362479 | 10362502 | 17 | - | 27260156 | G402 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.11047401672488599 | [733] | [1079,1218,928,680] | 1 | hSpCas9 | negative selection | 6890590 | 10360156 | 10360179 | 17 | + | 27260156 | G402 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.5944306073955637 | [657] | [1592,1319,1254,759] | 7 | hSpCas9 | negative selection | 6890591 | 10362438 | 10362461 | 17 | + | 27260156 | G402 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.7307270052241001 | [149] | [305,238,375,289] | 8 | hSpCas9 | negative selection | 6954847 | 10360004 | 10360027 | 17 | + | 27260156 | G402 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.822288282424327 | [516] | [816,1535,1036,1051] | 8 | hSpCas9 | negative selection | 6954848 | 10360060 | 10360083 | 17 | - | 27260156 | L33 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.5390343432294944 | [196] | [253,105,151,389] | 9 | hSpCas9 | negative selection | 7011840 | 10362479 | 10362502 | 17 | - | 27260156 | L33 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.10072480820285412 | [733] | [618,277,491,659] | -2 | hSpCas9 | negative selection | 7011841 | 10360156 | 10360179 | 17 | + | 27260156 | L33 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | -0.10525556119086821 | [657] | [597,278,328,643] | -2 | hSpCas9 | negative selection | 7011842 | 10362438 | 10362461 | 17 | + | 27260156 | L33 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.2868126827619262 | [149] | [180,68,99,222] | 6 | hSpCas9 | negative selection | 7076098 | 10360004 | 10360027 | 17 | + | 27260156 | L33 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | -0.14500537498108323 | [516] | [405,221,348,369] | -3 | hSpCas9 | negative selection | 7076099 | 10360060 | 10360083 | 17 | - | 27260156 | K562 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.0954861994799927 | [196] | [210,254,99,185] | 1 | hSpCas9 | negative selection | 7133091 | 10362479 | 10362502 | 17 | - | 27260156 | K562 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.15312095909932022 | [733] | [900,720,510,769] | 1 | hSpCas9 | negative selection | 7133092 | 10360156 | 10360179 | 17 | + | 27260156 | K562 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.11101387958180808 | [657] | [595,972,410,562] | 1 | hSpCas9 | negative selection | 7133093 | 10362438 | 10362461 | 17 | + | 27260156 | K562 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.7141781506713735 | [149] | [184,20,222,407] | 8 | hSpCas9 | negative selection | 7197349 | 10360004 | 10360027 | 17 | + | 27260156 | K562 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.3503008393138597 | [516] | [584,640,528,584] | 4 | hSpCas9 | negative selection | 7197350 | 10360060 | 10360083 | 17 | - | 27260156 | HT29 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.29409678884597235 | [196] | [384,393,267,157] | 6 | hSpCas9 | negative selection | 7254342 | 10362479 | 10362502 | 17 | - | 27260156 | HT29 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.21957774057582757 | [733] | [691,1109,843,473] | -4 | hSpCas9 | negative selection | 7254343 | 10360156 | 10360179 | 17 | + | 27260156 | HT29 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.04911304898209212 | [657] | [771,829,877,820] | 0 | hSpCas9 | negative selection | 7254344 | 10362438 | 10362461 | 17 | + | 27260156 | HT29 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.7394336369847636 | [149] | [356,337,362,179] | 9 | hSpCas9 | negative selection | 7318600 | 10360004 | 10360027 | 17 | + | 27260156 | HT29 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.36700394604812536 | [516] | [704,1049,883,631] | 7 | hSpCas9 | negative selection | 7318601 | 10360060 | 10360083 | 17 | - | 27260156 | MHHES1 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.5182122202957824 | [196] | [151,706,131,295] | 8 | hSpCas9 | negative selection | 7375593 | 10362479 | 10362502 | 17 | - | 27260156 | MHHES1 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.005346903764638755 | [733] | [1104,884,654,698] | 0 | hSpCas9 | negative selection | 7375594 | 10360156 | 10360179 | 17 | + | 27260156 | MHHES1 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.06508008564468892 | [657] | [1003,907,743,526] | 1 | hSpCas9 | negative selection | 7375595 | 10362438 | 10362461 | 17 | + | 27260156 | MHHES1 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.6298310244064584 | [149] | [423,217,205,216] | 9 | hSpCas9 | negative selection | 7439851 | 10360004 | 10360027 | 17 | + | 27260156 | MHHES1 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.16251627452989442 | [516] | [791,843,737,330] | 3 | hSpCas9 | negative selection | 7439852 | 10360060 | 10360083 | 17 | - | 27260156 | MEWO | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.5279884897331893 | [196] | [268,230,297] | 9 | hSpCas9 | negative selection | 7496844 | 10362479 | 10362502 | 17 | - | 27260156 | MEWO | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.048073295081941914 | [733] | [816,604,728] | 1 | hSpCas9 | negative selection | 7496845 | 10360156 | 10360179 | 17 | + | 27260156 | MEWO | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.005675776002848576 | [657] | [786,551,547] | 0 | hSpCas9 | negative selection | 7496846 | 10362438 | 10362461 | 17 | + | 27260156 | MEWO | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.2662360409756157 | [149] | [206,105,200] | 6 | hSpCas9 | negative selection | 7561102 | 10360004 | 10360027 | 17 | + | 27260156 | MEWO | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.3173940368781369 | [516] | [948,414,511] | 6 | hSpCas9 | negative selection | 7561103 | 10360060 | 10360083 | 17 | - | 27260156 | LNCAPCLONEFGC | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.3592528674753356 | [196] | [245,139,295,248] | 5 | hSpCas9 | negative selection | 7618095 | 10362479 | 10362502 | 17 | - | 27260156 | LNCAPCLONEFGC | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.04860905161086759 | [733] | [682,594,666,631] | -1 | hSpCas9 | negative selection | 7618096 | 10360156 | 10360179 | 17 | + | 27260156 | LNCAPCLONEFGC | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.25238161477249266 | [657] | [930,569,881,486] | 4 | hSpCas9 | negative selection | 7618097 | 10362438 | 10362461 | 17 | + | 27260156 | LNCAPCLONEFGC | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 1.3028964936406067 | [149] | [481,183,463,236] | 9 | hSpCas9 | negative selection | 7682353 | 10360004 | 10360027 | 17 | + | 27260156 | LNCAPCLONEFGC | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.6799843582028312 | [516] | [725,682,1048,591] | 9 | hSpCas9 | negative selection | 7682354 | 10360060 | 10360083 | 17 | - | 27260156 | PANC0327 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | -0.09903883787509793 | [196] | [216,107,148,190] | -1 | hSpCas9 | negative selection | 7739346 | 10362479 | 10362502 | 17 | - | 27260156 | PANC0327 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.029450655902086287 | [733] | [584,670,537,859] | 0 | hSpCas9 | negative selection | 7739347 | 10360156 | 10360179 | 17 | + | 27260156 | PANC0327 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.48430891840298984 | [657] | [919,851,604,896] | 7 | hSpCas9 | negative selection | 7739348 | 10362438 | 10362461 | 17 | + | 27260156 | PANC0327 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 1.2452529255893523 | [149] | [502,235,269,279] | 9 | hSpCas9 | negative selection | 7803604 | 10360004 | 10360027 | 17 | + | 27260156 | PANC0327 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.1682154474512862 | [516] | [833,370,546,356] | 2 | hSpCas9 | negative selection | 7803605 | 10360060 | 10360083 | 17 | - | 27260156 | NCIH2009 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.49489915812738516 | [196] | [496,251,437] | 6 | hSpCas9 | negative selection | 7860597 | 10362479 | 10362502 | 17 | - | 27260156 | NCIH2009 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.05454344962559288 | [733] | [1017,973,974] | 0 | hSpCas9 | negative selection | 7860598 | 10360156 | 10360179 | 17 | + | 27260156 | NCIH2009 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.10195301115751754 | [657] | [931,846,1170] | 1 | hSpCas9 | negative selection | 7860599 | 10362438 | 10362461 | 17 | + | 27260156 | NCIH2009 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.54661659310113 | [149] | [430,223,288] | 7 | hSpCas9 | negative selection | 7924855 | 10360004 | 10360027 | 17 | + | 27260156 | NCIH2009 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.25903585781525745 | [516] | [955,854,798] | 3 | hSpCas9 | negative selection | 7924856 | 10360060 | 10360083 | 17 | - | 27260156 | NCIH1373 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.5559772541457524 | [196] | [417,410,131,90] | 5 | hSpCas9 | negative selection | 7981848 | 10362479 | 10362502 | 17 | - | 27260156 | NCIH1373 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.1982172894991583 | [733] | [965,793,841,316] | 2 | hSpCas9 | negative selection | 7981849 | 10360156 | 10360179 | 17 | + | 27260156 | NCIH1373 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.28713139497320195 | [657] | [1058,880,925,195] | 3 | hSpCas9 | negative selection | 7981850 | 10362438 | 10362461 | 17 | + | 27260156 | NCIH1373 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 1.7686981079205253 | [149] | [967,319,456,167] | 9 | hSpCas9 | negative selection | 8046106 | 10360004 | 10360027 | 17 | + | 27260156 | NCIH1373 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.5561147175810756 | [516] | [1515,573,715,190] | 5 | hSpCas9 | negative selection | 8046107 | 10360060 | 10360083 | 17 | - | 27260156 | PATU8902 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.9337414967173273 | [196] | [559,215,509,846] | 8 | hSpCas9 | negative selection | 8103099 | 10362479 | 10362502 | 17 | - | 27260156 | PATU8902 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.11278721867341235 | [733] | [758,1292,819,936] | -1 | hSpCas9 | negative selection | 8103100 | 10360156 | 10360179 | 17 | + | 27260156 | PATU8902 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.13651006836782642 | [657] | [1210,1200,702,979] | 1 | hSpCas9 | negative selection | 8103101 | 10362438 | 10362461 | 17 | + | 27260156 | PATU8902 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.8981662897900694 | [149] | [426,317,211,676] | 8 | hSpCas9 | negative selection | 8167357 | 10360004 | 10360027 | 17 | + | 27260156 | PATU8902 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.8201829683082021 | [516] | [1076,1366,1076,1652] | 8 | hSpCas9 | negative selection | 8167358 | 10360060 | 10360083 | 17 | - | 27260156 | PANC1 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.16274499510124363 | [196] | [124,339,175,151] | 2 | hSpCas9 | negative selection | 8224350 | 10362479 | 10362502 | 17 | - | 27260156 | PANC1 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.1295786668051795 | [733] | [786,921,647,471] | 2 | hSpCas9 | negative selection | 8224351 | 10360156 | 10360179 | 17 | + | 27260156 | PANC1 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | -0.0459588623488032 | [657] | [594,680,556,398] | 0 | hSpCas9 | negative selection | 8224352 | 10362438 | 10362461 | 17 | + | 27260156 | PANC1 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.5639232284129456 | [149] | [217,129,261,143] | 8 | hSpCas9 | negative selection | 8288608 | 10360004 | 10360027 | 17 | + | 27260156 | PANC1 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.253359006495481 | [516] | [629,575,653,295] | 4 | hSpCas9 | negative selection | 8288609 | 10360060 | 10360083 | 17 | - | 27260156 | PANC0813 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.735210154094745 | [196] | [255,402,420,444] | 9 | hSpCas9 | negative selection | 8345601 | 10362479 | 10362502 | 17 | - | 27260156 | PANC0813 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.12586162768627618 | [733] | [793,885,686,791] | -2 | hSpCas9 | negative selection | 8345602 | 10360156 | 10360179 | 17 | + | 27260156 | PANC0813 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | -0.20542870787195328 | [657] | [742,593,764,589] | -3 | hSpCas9 | negative selection | 8345603 | 10362438 | 10362461 | 17 | + | 27260156 | PANC0813 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.27295972205949215 | [149] | [176,218,169,277] | 4 | hSpCas9 | negative selection | 8409859 | 10360004 | 10360027 | 17 | + | 27260156 | PANC0813 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.5235345233467864 | [516] | [851,942,868,826] | 8 | hSpCas9 | negative selection | 8409860 | 10360060 | 10360083 | 17 | - | 27260156 | RDES | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.49129560556389873 | [196] | [351,272,222,423] | 7 | hSpCas9 | negative selection | 8466852 | 10362479 | 10362502 | 17 | - | 27260156 | RDES | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.10740918265381938 | [733] | [775,656,968,1327] | 1 | hSpCas9 | negative selection | 8466853 | 10360156 | 10360179 | 17 | + | 27260156 | RDES | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.2566842427964028 | [657] | [656,715,1096,1253] | 4 | hSpCas9 | negative selection | 8466854 | 10362438 | 10362461 | 17 | + | 27260156 | RDES | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.9025019918467784 | [149] | [250,348,340,357] | 9 | hSpCas9 | negative selection | 8531110 | 10360004 | 10360027 | 17 | + | 27260156 | RDES | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.45303725424502095 | [516] | [592,711,902,1134] | 7 | hSpCas9 | negative selection | 8531111 | 10360060 | 10360083 | 17 | - | 27260156 | PC3 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.34767492010649337 | [196] | [135,331,423,195] | 7 | hSpCas9 | negative selection | 8588103 | 10362479 | 10362502 | 17 | - | 27260156 | PC3 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.23842657726965294 | [733] | [395,610,967,680] | -5 | hSpCas9 | negative selection | 8588104 | 10360156 | 10360179 | 17 | + | 27260156 | PC3 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.02951430448118042 | [657] | [358,544,1111,932] | 0 | hSpCas9 | negative selection | 8588105 | 10362438 | 10362461 | 17 | + | 27260156 | PC3 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.6452793610169469 | [149] | [119,209,444,276] | 9 | hSpCas9 | negative selection | 8652361 | 10360004 | 10360027 | 17 | + | 27260156 | PC3 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.09109012430163546 | [516] | [335,460,984,633] | 2 | hSpCas9 | negative selection | 8652362 | 10360060 | 10360083 | 17 | - | 27260156 | PATU8988T | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.24891729299393917 | [196] | [300,275,147,181] | 4 | hSpCas9 | negative selection | 8709354 | 10362479 | 10362502 | 17 | - | 27260156 | PATU8988T | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.27817465844299544 | [733] | [491,623,614,613] | -5 | hSpCas9 | negative selection | 8709355 | 10360156 | 10360179 | 17 | + | 27260156 | PATU8988T | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.3306481052321929 | [657] | [559,1021,636,1019] | 5 | hSpCas9 | negative selection | 8709356 | 10362438 | 10362461 | 17 | + | 27260156 | PATU8988T | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | -0.26685200377816964 | [149] | [87,89,112,193] | -4 | hSpCas9 | negative selection | 8773612 | 10360004 | 10360027 | 17 | + | 27260156 | PATU8988T | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.10914176183974938 | [516] | [412,686,473,600] | 2 | hSpCas9 | negative selection | 8773613 | 10360060 | 10360083 | 17 | - | 27260156 | T47D | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.310188019251354 | [196] | [331,338,244,215] | 6 | hSpCas9 | negative selection | 8830605 | 10362479 | 10362502 | 17 | - | 27260156 | T47D | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.050752693890154355 | [733] | [812,785,867,837] | -1 | hSpCas9 | negative selection | 8830606 | 10360156 | 10360179 | 17 | + | 27260156 | T47D | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.16763363630994588 | [657] | [756,853,750,1090] | 3 | hSpCas9 | negative selection | 8830607 | 10362438 | 10362461 | 17 | + | 27260156 | T47D | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.4918767599121845 | [149] | [215,229,299,236] | 8 | hSpCas9 | negative selection | 8894863 | 10360004 | 10360027 | 17 | + | 27260156 | T47D | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.25464180953904303 | [516] | [759,739,640,732] | 5 | hSpCas9 | negative selection | 8894864 | 10360060 | 10360083 | 17 | - | 27260156 | SU8686 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.8821753467135245 | [196] | [394,364,324,343] | 9 | hSpCas9 | negative selection | 8951856 | 10362479 | 10362502 | 17 | - | 27260156 | SU8686 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.04192502517872965 | [733] | [759,630,622,1033] | 0 | hSpCas9 | negative selection | 8951857 | 10360156 | 10360179 | 17 | + | 27260156 | SU8686 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | -0.10460118060889906 | [657] | [572,545,543,800] | -2 | hSpCas9 | negative selection | 8951858 | 10362438 | 10362461 | 17 | + | 27260156 | SU8686 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.4965959571553433 | [149] | [161,235,178,271] | 8 | hSpCas9 | negative selection | 9016114 | 10360004 | 10360027 | 17 | + | 27260156 | SU8686 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.1589773415715534 | [516] | [432,477,721,705] | 2 | hSpCas9 | negative selection | 9016115 | 10360060 | 10360083 | 17 | - | 27260156 | SKES1 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.17129442628140734 | [196] | [190,213,278,195] | 3 | hSpCas9 | negative selection | 9073107 | 10362479 | 10362502 | 17 | - | 27260156 | SKES1 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.06326116034046048 | [733] | [660,751,770,620] | -1 | hSpCas9 | negative selection | 9073108 | 10360156 | 10360179 | 17 | + | 27260156 | SKES1 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.09707540071228815 | [657] | [937,838,620,479] | 2 | hSpCas9 | negative selection | 9073109 | 10362438 | 10362461 | 17 | + | 27260156 | SKES1 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.5279022795585568 | [149] | [212,238,139,265] | 9 | hSpCas9 | negative selection | 9137365 | 10360004 | 10360027 | 17 | + | 27260156 | SKES1 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.08535787800641709 | [516] | [504,567,472,624] | 1 | hSpCas9 | negative selection | 9137366 | 10360060 | 10360083 | 17 | - | 27260156 | TOV112D | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.18075930437306775 | [196] | [214,263,149,272] | 3 | hSpCas9 | negative selection | 9194358 | 10362479 | 10362502 | 17 | - | 27260156 | TOV112D | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.10803299806389588 | [733] | [644,797,675,634] | -2 | hSpCas9 | negative selection | 9194359 | 10360156 | 10360179 | 17 | + | 27260156 | TOV112D | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | -0.1619947351081184 | [657] | [659,551,478,658] | -3 | hSpCas9 | negative selection | 9194360 | 10362438 | 10362461 | 17 | + | 27260156 | TOV112D | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.7929271199939791 | [149] | [210,312,208,314] | 9 | hSpCas9 | negative selection | 9258616 | 10360004 | 10360027 | 17 | + | 27260156 | TOV112D | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.2708125414666831 | [516] | [621,906,518,521] | 5 | hSpCas9 | negative selection | 9258617 | 10360060 | 10360083 | 17 | - | 27260156 | TC71 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.2173768895723358 | [196] | [209,262,255,253] | 5 | hSpCas9 | negative selection | 9315609 | 10362479 | 10362502 | 17 | - | 27260156 | TC71 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.0698731810054366 | [733] | [712,884,587,822] | -2 | hSpCas9 | negative selection | 9315610 | 10360156 | 10360179 | 17 | + | 27260156 | TC71 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | -0.12753345342375616 | [657] | [659,689,579,654] | -3 | hSpCas9 | negative selection | 9315611 | 10362438 | 10362461 | 17 | + | 27260156 | TC71 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.5772126851452515 | [149] | [231,273,259,189] | 9 | hSpCas9 | negative selection | 9379867 | 10360004 | 10360027 | 17 | + | 27260156 | TC71 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | -0.035615197368439586 | [516] | [570,508,540,540] | -1 | hSpCas9 | negative selection | 9379868 | 10360060 | 10360083 | 17 | - | 27260156 | TC32 | viability | TAAATTGGCAGCGGAGAATCCGG | MYH13 | ENSG00000006788 | 0.4222773812188185 | [196] | [214,239,259,271] | 7 | hSpCas9 | negative selection | 9436860 | 10362479 | 10362502 | 17 | - | 27260156 | TC32 | viability | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.18324236668696448 | [733] | [742,653,851,907] | 3 | hSpCas9 | negative selection | 9436861 | 10360156 | 10360179 | 17 | + | 27260156 | TC32 | viability | CTCACGTGATGAGGATAGACTGG | MYH13 | ENSG00000006788 | 0.1619116527862322 | [657] | [582,436,1083,809] | 3 | hSpCas9 | negative selection | 9436862 | 10362438 | 10362461 | 17 | + | 27260156 | TC32 | viability | GTCCTCGATCTTGTCAAATTTGG | MYH13 | ENSG00000006788 | 0.5590308172864291 | [149] | [231,149,207,248] | 8 | hSpCas9 | negative selection | 9501118 | 10360004 | 10360027 | 17 | + | 27260156 | TC32 | viability | CTGCAATTGTTGCAAAATACTGG | MYH13 | ENSG00000006788 | 0.6375266804058178 | [516] | [700,616,1022,740] | 9 | hSpCas9 | negative selection | 9501119 | 10346721 | 10346744 | 17 | + | 27869803 | HPAFII | viability after 27 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.4695831639833671 | [376] | [394,173,NaN] | 4 | hSpCas9 | negative selection | 9559069 | 10354725 | 10354748 | 17 | + | 27869803 | HPAFII | viability after 27 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 1.285670783953009 | [100] | [165,98,NaN] | 9 | hSpCas9 | negative selection | 9559070 | 10362479 | 10362502 | 17 | - | 27869803 | HPAFII | viability after 27 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.2507567868828089 | [128] | [104,16,NaN] | -2 | hSpCas9 | negative selection | 9559071 | 10364509 | 10364532 | 17 | - | 27869803 | HPAFII | viability after 27 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.7418217620185474 | [455] | [359,434,NaN] | 6 | hSpCas9 | negative selection | 9559072 | 10346721 | 10346744 | 17 | + | 27869803 | HPAFII | viability after 15 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.5585899897349232 | [376] | [954,373,NaN] | 6 | hSpCas9 | negative selection | 9641518 | 10354725 | 10354748 | 17 | + | 27869803 | HPAFII | viability after 15 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 1.3068298226092994 | [100] | [381,197,NaN] | 9 | hSpCas9 | negative selection | 9641519 | 10362479 | 10362502 | 17 | - | 27869803 | HPAFII | viability after 15 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.008554288200524396 | [128] | [292,43,NaN] | 0 | hSpCas9 | negative selection | 9641520 | 10364509 | 10364532 | 17 | - | 27869803 | HPAFII | viability after 15 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.8049302008703638 | [455] | [1145,675,NaN] | 8 | hSpCas9 | negative selection | 9641521 | 10346721 | 10346744 | 17 | + | 27869803 | ASPC1 | viability after 36 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 1.5936858887747052 | [1038] | [715,1300,1184] | 9 | hSpCas9 | negative selection | 9723967 | 10354725 | 10354748 | 17 | + | 27869803 | ASPC1 | viability after 36 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 1.0961817634063653 | [350] | [174,401,208] | 8 | hSpCas9 | negative selection | 9723968 | 10362479 | 10362502 | 17 | - | 27869803 | ASPC1 | viability after 36 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.9567934055359377 | [293] | [106,12,45] | -7 | hSpCas9 | negative selection | 9723969 | 10364509 | 10364532 | 17 | - | 27869803 | ASPC1 | viability after 36 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | -0.3740137715749249 | [989] | [263,191,324] | -4 | hSpCas9 | negative selection | 9723970 | 10346721 | 10346744 | 17 | + | 27869803 | PATU8988S | viability after 35 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.289877468840944 | [892] | [304,574,NaN] | 3 | hSpCas9 | negative selection | 9806416 | 10354725 | 10354748 | 17 | + | 27869803 | PATU8988S | viability after 35 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | -0.45858912583007405 | [378] | [144,76,NaN] | -5 | hSpCas9 | negative selection | 9806417 | 10362479 | 10362502 | 17 | - | 27869803 | PATU8988S | viability after 35 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.9611328377008934 | [222] | [109,239,NaN] | 8 | hSpCas9 | negative selection | 9806418 | 10364509 | 10364532 | 17 | - | 27869803 | PATU8988S | viability after 35 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.31444811493129043 | [1001] | [429,573,NaN] | 3 | hSpCas9 | negative selection | 9806419 | 10346721 | 10346744 | 17 | + | 27869803 | PATU8988S | viability after 31 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.4596604524277028 | [892] | [318,706,NaN] | 5 | hSpCas9 | negative selection | 9888865 | 10354725 | 10354748 | 17 | + | 27869803 | PATU8988S | viability after 31 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | -0.1981201442325462 | [378] | [191,54,NaN] | -2 | hSpCas9 | negative selection | 9888866 | 10362479 | 10362502 | 17 | - | 27869803 | PATU8988S | viability after 31 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | 0.47304686158463494 | [222] | [45,221,NaN] | 6 | hSpCas9 | negative selection | 9888867 | 10364509 | 10364532 | 17 | - | 27869803 | PATU8988S | viability after 31 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.3952384046148888 | [1001] | [429,646,NaN] | 5 | hSpCas9 | negative selection | 9888868 | 10346721 | 10346744 | 17 | + | 27869803 | HPAFII | viability after 35 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.36694709199259945 | [376] | [390,82,NaN] | 2 | hSpCas9 | negative selection | 9971314 | 10354725 | 10354748 | 17 | + | 27869803 | HPAFII | viability after 35 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 0.7301787224593418 | [100] | [73,96,NaN] | 5 | hSpCas9 | negative selection | 9971315 | 10362479 | 10362502 | 17 | - | 27869803 | HPAFII | viability after 35 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -1.569188781272161 | [128] | [37,3,NaN] | -7 | hSpCas9 | negative selection | 9971316 | 10364509 | 10364532 | 17 | - | 27869803 | HPAFII | viability after 35 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 1.1371871013461976 | [455] | [368,663,NaN] | 7 | hSpCas9 | negative selection | 9971317 | 10346721 | 10346744 | 17 | + | 27869803 | HPAFII | viability after 31 days | CCTTCACCCTTGGACAGCACAGG | MYH13 | ENSG00000006788 | 0.388357795254036 | [376] | [442,95,NaN] | 3 | hSpCas9 | negative selection | 10053763 | 10354725 | 10354748 | 17 | + | 27869803 | HPAFII | viability after 31 days | GACCTCTCCTTGGCTCACGAAGG | MYH13 | ENSG00000006788 | 1.019215320778857 | [100] | [89,141,NaN] | 7 | hSpCas9 | negative selection | 10053764 | 10362479 | 10362502 | 17 | - | 27869803 | HPAFII | viability after 31 days | GCTCACTCTGAACAATGACCAGG | MYH13 | ENSG00000006788 | -0.7670110341108629 | [128] | [76,4,NaN] | -5 | hSpCas9 | negative selection | 10053765 | 10364509 | 10364532 | 17 | - | 27869803 | HPAFII | viability after 31 days | CATGAGCTCTGACGCAGAAATGG | MYH13 | ENSG00000006788 | 0.9080800735369023 | [455] | [451,510,NaN] | 6 | hSpCas9 | negative selection | 10053766 | 10319052 | 10319075 | 17 | - | 28162770 | P31FUJ | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -3.645185250247245 | [180] | [16] | -9 | hSpCas9 | negative selection | 10196439 | 10345234 | 10345257 | 17 | - | 28162770 | P31FUJ | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | -0.4647489324640752 | [100] | [85] | -4 | hSpCas9 | negative selection | 10196440 | 10319158 | 10319181 | 17 | - | 28162770 | P31FUJ | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 0.8684811314228029 | [164] | [353] | 8 | hSpCas9 | negative selection | 10196441 | 10319092 | 10319115 | 17 | - | 28162770 | P31FUJ | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.41638273926110403 | [226] | [355] | 4 | hSpCas9 | negative selection | 10196442 | 10319052 | 10319075 | 17 | - | 28162770 | TF1 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | NaN | [NaN] | [32] | 1 | hSpCas9 | negative selection | 10365805 | 10345234 | 10345257 | 17 | - | 28162770 | TF1 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | NaN | [NaN] | [28] | 1 | hSpCas9 | negative selection | 10365806 | 10319158 | 10319181 | 17 | - | 28162770 | TF1 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | NaN | [NaN] | [150] | 1 | hSpCas9 | negative selection | 10365807 | 10319092 | 10319115 | 17 | - | 28162770 | TF1 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | NaN | [NaN] | [222] | 1 | hSpCas9 | negative selection | 10365808 | 10319052 | 10319075 | 17 | - | 28162770 | SKM1 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -1.2253573922532137 | [40] | [30] | -7 | hSpCas9 | negative selection | 10535171 | 10345234 | 10345257 | 17 | - | 28162770 | SKM1 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | 0.2065674541747653 | [24] | [50] | 2 | hSpCas9 | negative selection | 10535172 | 10319158 | 10319181 | 17 | - | 28162770 | SKM1 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | -0.04827755384568155 | [30] | [52] | 0 | hSpCas9 | negative selection | 10535173 | 10319092 | 10319115 | 17 | - | 28162770 | SKM1 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.4246382695611196 | [58] | [139] | 4 | hSpCas9 | negative selection | 10535174 | 10319052 | 10319075 | 17 | - | 28162770 | SKM1 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -1.2253573922532137 | [40] | [30] | -7 | hSpCas9 | negative selection | 10704537 | 10345234 | 10345257 | 17 | - | 28162770 | SKM1 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | 0.2065674541747653 | [24] | [50] | 2 | hSpCas9 | negative selection | 10704538 | 10319158 | 10319181 | 17 | - | 28162770 | SKM1 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | -0.04827755384568155 | [30] | [52] | 0 | hSpCas9 | negative selection | 10704539 | 10319092 | 10319115 | 17 | - | 28162770 | SKM1 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.4246382695611196 | [58] | [139] | 4 | hSpCas9 | negative selection | 10704540 | 10319052 | 10319075 | 17 | - | 28162770 | PL21 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -2.42134876225695 | [159] | [12] | -8 | hSpCas9 | negative selection | 10873903 | 10345234 | 10345257 | 17 | - | 28162770 | PL21 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | -2.5724498894076078 | [81] | [5] | -9 | hSpCas9 | negative selection | 10873904 | 10319158 | 10319181 | 17 | - | 28162770 | PL21 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | -0.500300103651772 | [77] | [23] | -4 | hSpCas9 | negative selection | 10873905 | 10319092 | 10319115 | 17 | - | 28162770 | PL21 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | -0.20003992606241056 | [160] | [60] | -1 | hSpCas9 | negative selection | 10873906 | 10319052 | 10319075 | 17 | - | 28162770 | P31FUJ | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -3.645185250247245 | [180] | [16] | -9 | hSpCas9 | negative selection | 11043269 | 10345234 | 10345257 | 17 | - | 28162770 | P31FUJ | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | -0.4647489324640752 | [100] | [85] | -4 | hSpCas9 | negative selection | 11043270 | 10319158 | 10319181 | 17 | - | 28162770 | P31FUJ | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 0.8684811314228029 | [164] | [353] | 8 | hSpCas9 | negative selection | 11043271 | 10319092 | 10319115 | 17 | - | 28162770 | P31FUJ | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.41638273926110403 | [226] | [355] | 4 | hSpCas9 | negative selection | 11043272 | 10319052 | 10319075 | 17 | - | 28162770 | OCIAML5 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -2.157875000388082 | [88] | [35] | -8 | hSpCas9 | negative selection | 11212635 | 10345234 | 10345257 | 17 | - | 28162770 | OCIAML5 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | 1.178307078179522 | [46] | [191] | 8 | hSpCas9 | negative selection | 11212636 | 10319158 | 10319181 | 17 | - | 28162770 | OCIAML5 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 0.5414147850483992 | [58] | [154] | 5 | hSpCas9 | negative selection | 11212637 | 10319092 | 10319115 | 17 | - | 28162770 | OCIAML5 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.36008666596761285 | [100] | [233] | 3 | hSpCas9 | negative selection | 11212638 | 10319052 | 10319075 | 17 | - | 28162770 | EOL1 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -0.8124178225956719 | [299] | [89] | -5 | hSpCas9 | negative selection | 11382001 | 10345234 | 10345257 | 17 | - | 28162770 | EOL1 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | -0.057530320432203075 | [159] | [80] | 0 | hSpCas9 | negative selection | 11382002 | 10319158 | 10319181 | 17 | - | 28162770 | EOL1 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 1.1469401929069827 | [107] | [125] | 8 | hSpCas9 | negative selection | 11382003 | 10319092 | 10319115 | 17 | - | 28162770 | EOL1 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.4509841956852351 | [217] | [156] | 4 | hSpCas9 | negative selection | 11382004 | 10319052 | 10319075 | 17 | - | 28162770 | MOLM13 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -1.0321842215900643 | [197] | [69] | -5 | hSpCas9 | negative selection | 11551367 | 10345234 | 10345257 | 17 | - | 28162770 | MOLM13 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | -0.39688323776119794 | [172] | [94] | -2 | hSpCas9 | negative selection | 11551368 | 10319158 | 10319181 | 17 | - | 28162770 | MOLM13 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | -0.3424493989518469 | [120] | [68] | -2 | hSpCas9 | negative selection | 11551369 | 10319092 | 10319115 | 17 | - | 28162770 | MOLM13 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.6506084952029438 | [236] | [268] | 5 | hSpCas9 | negative selection | 11551370 | 10319052 | 10319075 | 17 | - | 28162770 | HEL | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -0.567621033841194 | [198] | [85] | -4 | hSpCas9 | negative selection | 11720733 | 10345234 | 10345257 | 17 | - | 28162770 | HEL | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | 1.460535500779608 | [117] | [207] | 9 | hSpCas9 | negative selection | 11720734 | 10319158 | 10319181 | 17 | - | 28162770 | HEL | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 0.39193072849982247 | [93] | [78] | 3 | hSpCas9 | negative selection | 11720735 | 10319092 | 10319115 | 17 | - | 28162770 | HEL | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.4696741230274773 | [229] | [203] | 4 | hSpCas9 | negative selection | 11720736 | 10319052 | 10319075 | 17 | - | 28162770 | MV411 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -1.3559034792532354 | [157] | [51] | -7 | hSpCas9 | negative selection | 11890099 | 10345234 | 10345257 | 17 | - | 28162770 | MV411 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | -0.09448201929205302 | [108] | [85] | 0 | hSpCas9 | negative selection | 11890100 | 10319158 | 10319181 | 17 | - | 28162770 | MV411 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 1.5884744686178423 | [59] | [151] | 9 | hSpCas9 | negative selection | 11890101 | 10319092 | 10319115 | 17 | - | 28162770 | MV411 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | -0.15619518522381906 | [167] | [126] | -1 | hSpCas9 | negative selection | 11890102 | 10319052 | 10319075 | 17 | - | 28162770 | MONOMAC1 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | 0.08234555286172378 | [116] | [141] | 0 | hSpCas9 | negative selection | 12059465 | 10345234 | 10345257 | 17 | - | 28162770 | MONOMAC1 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | -0.013324893887165401 | [80] | [91] | 0 | hSpCas9 | negative selection | 12059466 | 10319158 | 10319181 | 17 | - | 28162770 | MONOMAC1 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 0.2816167515152618 | [60] | [84] | 3 | hSpCas9 | negative selection | 12059467 | 10319092 | 10319115 | 17 | - | 28162770 | MONOMAC1 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | -0.6076691672183966 | [108] | [81] | -5 | hSpCas9 | negative selection | 12059468 | 10319052 | 10319075 | 17 | - | 28162770 | OCIAML2 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -3.1028980407416737 | [30] | [19] | -9 | hSpCas9 | negative selection | 12228831 | 10345234 | 10345257 | 17 | - | 28162770 | OCIAML2 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | 0.44190733350749933 | [16] | [127] | 4 | hSpCas9 | negative selection | 12228832 | 10319158 | 10319181 | 17 | - | 28162770 | OCIAML2 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 0.11433267547899495 | [16] | [101] | 1 | hSpCas9 | negative selection | 12228833 | 10319092 | 10319115 | 17 | - | 28162770 | OCIAML2 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.5862013973545148 | [27] | [232] | 6 | hSpCas9 | negative selection | 12228834 | 10319052 | 10319075 | 17 | - | 28162770 | OCIAML3 | viability | GAGAGGCTGGAAGAAGCCAGTGG | MYH13 | ENSG00000006788 | -2.1085808131539214 | [49] | [34] | -8 | hSpCas9 | negative selection | 12398197 | 10345234 | 10345257 | 17 | - | 28162770 | OCIAML3 | viability | GGAGTTCATTGACTTCGGAATGG | MYH13 | ENSG00000006788 | -0.2552057268724046 | [16] | [42] | -2 | hSpCas9 | negative selection | 12398198 | 10319158 | 10319181 | 17 | - | 28162770 | OCIAML3 | viability | GGCCCGCATAGAAGAGCTGGAGG | MYH13 | ENSG00000006788 | 0.005905201862964393 | [31] | [96] | 0 | hSpCas9 | negative selection | 12398199 | 10319092 | 10319115 | 17 | - | 28162770 | OCIAML3 | viability | GCAGCGCTCAGATCTGGCCAGGG | MYH13 | ENSG00000006788 | 0.04070789559409277 | [37] | [117] | 0 | hSpCas9 | negative selection | 12398200 |