Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:23327
• Symbol:NEDD4L
• Description:NEDD4 like E3 ubiquitin protein ligase

DataSource: http://genomecrispr.dkfz.de/#!/results/NEDD4L

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
58333828	58333851	18	-	26472758	Jiyoye	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	1.2516056730406313	[224]	[403]	7	hSpCas9	negative selection	107559
58341787	58341810	18	-	26472758	Jiyoye	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	2.0966320500981355	[70]	[228]	9	hSpCas9	negative selection	107560
58325123	58325146	18	+	26472758	Jiyoye	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.7951010351674759	[93]	[122]	5	hSpCas9	negative selection	107561
58330811	58330834	18	-	26472758	Jiyoye	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	1.2036419874207411	[56]	[98]	7	hSpCas9	negative selection	107562
58389165	58389188	18	-	26472758	Jiyoye	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	-0.2302545391094184	[13]	[8]	-2	hSpCas9	negative selection	107563
58329101	58329124	18	-	26472758	Jiyoye	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	-0.21431299524039682	[19]	[12]	-1	hSpCas9	negative selection	107564
58330801	58330824	18	-	26472758	Jiyoye	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	-2.746629954573162	[88]	[9]	-9	hSpCas9	negative selection	107565
58330833	58330856	18	-	26472758	Jiyoye	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	-0.20002233769000322	[424]	[278]	-1	hSpCas9	negative selection	107566
58341727	58341750	18	+	26472758	Jiyoye	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.15353957296860543	[235]	[159]	-1	hSpCas9	negative selection	107567
58341768	58341791	18	-	26472758	Jiyoye	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	-5.523561956057013	[60]	[0]	-9	hSpCas9	negative selection	107568
58333828	58333851	18	-	26472758	KBM7	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	0.35719587253102647	[1160,1061]	[751,595]	4	hSpCas9	negative selection	298677
58341787	58341810	18	-	26472758	KBM7	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	0.09773745457661417	[456,493]	[243,238]	0	hSpCas9	negative selection	298678
58325123	58325146	18	+	26472758	KBM7	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.3434481231555012	[440,236]	[130,255]	3	hSpCas9	negative selection	298679
58330811	58330834	18	-	26472758	KBM7	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-0.8331764181731185	[729,440]	[200,106]	-6	hSpCas9	negative selection	298680
58389165	58389188	18	-	26472758	KBM7	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	0.6453454208529965	[82,113]	[36,106]	7	hSpCas9	negative selection	298681
58329101	58329124	18	-	26472758	KBM7	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	-0.41565397532612325	[98,82]	[32,30]	-4	hSpCas9	negative selection	298682
58330801	58330824	18	-	26472758	KBM7	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	-0.2547202667039754	[168,119]	[98,17]	-2	hSpCas9	negative selection	298683
58330833	58330856	18	-	26472758	KBM7	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.25277721187343505	[1796,1783]	[986,1025]	2	hSpCas9	negative selection	298684
58341727	58341750	18	+	26472758	KBM7	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.06810021165003888	[748,850]	[279,436]	0	hSpCas9	negative selection	298685
58341768	58341791	18	-	26472758	KBM7	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	0.8491620374666642	[25,64]	[41,38]	8	hSpCas9	negative selection	298686
58333828	58333851	18	-	26472758	Raji	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	0.6013515038741629	[408]	[143]	5	hSpCas9	negative selection	489795
58341787	58341810	18	-	26472758	Raji	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	0.23817014290895344	[273]	[74]	2	hSpCas9	negative selection	489796
58325123	58325146	18	+	26472758	Raji	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	1.0954108937075235	[120]	[59]	8	hSpCas9	negative selection	489797
58330811	58330834	18	-	26472758	Raji	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-0.5224755033218798	[358]	[57]	-4	hSpCas9	negative selection	489798
58389165	58389188	18	-	26472758	Raji	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	-0.3706637614310446	[77]	[13]	-3	hSpCas9	negative selection	489799
58329101	58329124	18	-	26472758	Raji	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.9605421470443283	[30]	[13]	8	hSpCas9	negative selection	489800
58330801	58330824	18	-	26472758	Raji	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	-0.047894690104311355	[97]	[21]	0	hSpCas9	negative selection	489801
58330833	58330856	18	-	26472758	Raji	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.5687909977904773	[795]	[273]	5	hSpCas9	negative selection	489802
58341727	58341750	18	+	26472758	Raji	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.35105261634046225	[249]	[73]	3	hSpCas9	negative selection	489803
58341768	58341791	18	-	26472758	Raji	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	-0.3951168051555842	[16]	[2]	-3	hSpCas9	negative selection	489804
58333828	58333851	18	-	26472758	K562	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	0.23277228669183336	[994]	[986]	1	hSpCas9	negative selection	680913
58341787	58341810	18	-	26472758	K562	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	0.11222411530157728	[433]	[395]	0	hSpCas9	negative selection	680914
58325123	58325146	18	+	26472758	K562	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.7221602715737108	[241]	[336]	6	hSpCas9	negative selection	680915
58330811	58330834	18	-	26472758	K562	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-1.1104239896936505	[398]	[155]	-6	hSpCas9	negative selection	680916
58389165	58389188	18	-	26472758	K562	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	-1.0319125007808048	[108]	[44]	-5	hSpCas9	negative selection	680917
58329101	58329124	18	-	26472758	K562	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.20879481793572552	[40]	[39]	1	hSpCas9	negative selection	680918
58330801	58330824	18	-	26472758	K562	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	0.2121423246426909	[225]	[220]	1	hSpCas9	negative selection	680919
58330833	58330856	18	-	26472758	K562	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.19811381801346162	[1392]	[1348]	1	hSpCas9	negative selection	680920
58341727	58341750	18	+	26472758	K562	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.4809710050393257	[448]	[528]	4	hSpCas9	negative selection	680921
58341768	58341791	18	-	26472758	K562	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	2.5007584809262324	[26]	[128]	9	hSpCas9	negative selection	680922
58044687	58044710	18	+	26627737	DLD1	viability	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	0.05879413219866736	[781]	[226,212,312]	0	hSpCas9	negative selection	801783
58315984	58316007	18	+	26627737	DLD1	viability	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	-1.0636898033158313	[395]	[58,72,47]	-7	hSpCas9	negative selection	801784
58322465	58322488	18	+	26627737	DLD1	viability	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.2865047495596531	[254]	[60,103,122]	3	hSpCas9	negative selection	801785
58325025	58325048	18	+	26627737	DLD1	viability	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.05293519137708658	[1132]	[446,414,258]	0	hSpCas9	negative selection	801786
58329089	58329112	18	+	26627737	DLD1	viability	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.0017416468271395091	[279]	[78,74,104]	0	hSpCas9	negative selection	801787
58333887	58333910	18	-	26627737	DLD1	viability	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-0.23898740836617482	[246]	[77,88,34]	-3	hSpCas9	negative selection	801788
58044687	58044710	18	+	26627737	GBM cells	viability after 5 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	0.16245017498124303	[478]	[297,276]	2	hSpCas9	negative selection	884098
58315984	58316007	18	+	26627737	GBM cells	viability after 5 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	-0.24547603444948934	[188]	[80,89]	-4	hSpCas9	negative selection	884099
58322465	58322488	18	+	26627737	GBM cells	viability after 5 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.48965872820084794	[165]	[127,121]	7	hSpCas9	negative selection	884100
58325025	58325048	18	+	26627737	GBM cells	viability after 5 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.614143539400597	[320]	[269,256]	8	hSpCas9	negative selection	884101
58329089	58329112	18	+	26627737	GBM cells	viability after 5 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	0.13480213870635638	[151]	[79,98]	2	hSpCas9	negative selection	884102
58333887	58333910	18	-	26627737	GBM cells	viability after 5 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	0.0990534893750058	[167]	[94,97]	1	hSpCas9	negative selection	884103
58044687	58044710	18	+	26627737	GBM cells	viability after 13 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.06156379272595769	[478]	[253,244]	0	hSpCas9	negative selection	966413
58315984	58316007	18	+	26627737	GBM cells	viability after 13 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.25580570124725366	[188]	[106,134]	3	hSpCas9	negative selection	966414
58322465	58322488	18	+	26627737	GBM cells	viability after 13 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.36513613318303384	[165]	[131,102]	5	hSpCas9	negative selection	966415
58325025	58325048	18	+	26627737	GBM cells	viability after 13 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.6910811508623477	[320]	[321,247]	8	hSpCas9	negative selection	966416
58329089	58329112	18	+	26627737	GBM cells	viability after 13 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.05641491260491738	[151]	[75,81]	0	hSpCas9	negative selection	966417
58333887	58333910	18	-	26627737	GBM cells	viability after 13 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-0.23751591083151058	[167]	[89,66]	-3	hSpCas9	negative selection	966418
58044687	58044710	18	+	26627737	GBM cells	viability after 21 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.14053011062279896	[478]	[245,226]	-1	hSpCas9	negative selection	1048728
58315984	58316007	18	+	26627737	GBM cells	viability after 21 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	-0.02443263087834635	[188]	[101,99]	0	hSpCas9	negative selection	1048729
58322465	58322488	18	+	26627737	GBM cells	viability after 21 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.12039434154727924	[165]	[108,87]	1	hSpCas9	negative selection	1048730
58325025	58325048	18	+	26627737	GBM cells	viability after 21 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.7680149834986508	[320]	[320,274]	7	hSpCas9	negative selection	1048731
58329089	58329112	18	+	26627737	GBM cells	viability after 21 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.06797739803072322	[151]	[83,73]	0	hSpCas9	negative selection	1048732
58333887	58333910	18	-	26627737	GBM cells	viability after 21 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	0.8357586704750537	[167]	[176,149]	8	hSpCas9	negative selection	1048733
58044687	58044710	18	+	26627737	RPE1	viability after 9 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.4925532297250471	[1560]	[335,361]	-3	hSpCas9	negative selection	1131043
58315984	58316007	18	+	26627737	RPE1	viability after 9 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	-1.0320173194331492	[1230]	[263,90]	-6	hSpCas9	negative selection	1131044
58322465	58322488	18	+	26627737	RPE1	viability after 9 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.6017073475663789	[449]	[139,308]	4	hSpCas9	negative selection	1131045
58325025	58325048	18	+	26627737	RPE1	viability after 9 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.25317876325568256	[1542]	[783,306]	1	hSpCas9	negative selection	1131046
58329089	58329112	18	+	26627737	RPE1	viability after 9 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-2.4794870359051973	[626]	[39,28]	-9	hSpCas9	negative selection	1131047
58333887	58333910	18	-	26627737	RPE1	viability after 9 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	1.4461002928248967	[123]	[117,89]	7	hSpCas9	negative selection	1131048
58044687	58044710	18	+	26627737	RPE1	viability after 12 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.2973071939060429	[1560]	[367,312]	-2	hSpCas9	negative selection	1213358
58315984	58316007	18	+	26627737	RPE1	viability after 12 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	-0.6334400069395059	[1230]	[151,277]	-4	hSpCas9	negative selection	1213359
58322465	58322488	18	+	26627737	RPE1	viability after 12 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.5817205675794466	[449]	[110,254]	4	hSpCas9	negative selection	1213360
58325025	58325048	18	+	26627737	RPE1	viability after 12 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	-0.10081973297866398	[1542]	[422,347]	0	hSpCas9	negative selection	1213361
58329089	58329112	18	+	26627737	RPE1	viability after 12 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-2.6006807344680865	[626]	[36,17]	-9	hSpCas9	negative selection	1213362
58333887	58333910	18	-	26627737	RPE1	viability after 12 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	1.0887564896155337	[123]	[82,57]	6	hSpCas9	negative selection	1213363
58044687	58044710	18	+	26627737	RPE1	viability after 15 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.18809129292616256	[1560]	[353,419]	-1	hSpCas9	negative selection	1295673
58315984	58316007	18	+	26627737	RPE1	viability after 15 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	-0.8374902714524473	[1230]	[173,214]	-5	hSpCas9	negative selection	1295674
58322465	58322488	18	+	26627737	RPE1	viability after 15 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	1.057458993683523	[449]	[127,396]	6	hSpCas9	negative selection	1295675
58325025	58325048	18	+	26627737	RPE1	viability after 15 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	-0.3969379514943503	[1542]	[359,303]	-2	hSpCas9	negative selection	1295676
58329089	58329112	18	+	26627737	RPE1	viability after 15 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-1.8784878336390325	[626]	[62,33]	-8	hSpCas9	negative selection	1295677
58333887	58333910	18	-	26627737	RPE1	viability after 15 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	1.1449399058468148	[123]	[129,26]	6	hSpCas9	negative selection	1295678
58044687	58044710	18	+	26627737	RPE1	viability after 18 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.06427292899147385	[1560]	[239,576]	0	hSpCas9	negative selection	1377988
58315984	58316007	18	+	26627737	RPE1	viability after 18 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	-0.31241112953337963	[1230]	[209,328]	-2	hSpCas9	negative selection	1377989
58322465	58322488	18	+	26627737	RPE1	viability after 18 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.4817746058549494	[449]	[142,197]	3	hSpCas9	negative selection	1377990
58325025	58325048	18	+	26627737	RPE1	viability after 18 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	-0.2665936350918302	[1542]	[437,247]	-2	hSpCas9	negative selection	1377991
58329089	58329112	18	+	26627737	RPE1	viability after 18 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-1.8470465415160506	[626]	[47,45]	-8	hSpCas9	negative selection	1377992
58333887	58333910	18	-	26627737	RPE1	viability after 18 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	0.06455959865245653	[123]	[63,3]	0	hSpCas9	negative selection	1377993
58044687	58044710	18	+	26627737	HeLa	viability after 8 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.26144145575732436	[940]	[357,322,346]	-3	hSpCas9	negative selection	1460303
58315984	58316007	18	+	26627737	HeLa	viability after 8 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.3729523633936839	[309]	[141,142,227]	3	hSpCas9	negative selection	1460304
58322465	58322488	18	+	26627737	HeLa	viability after 8 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.5047699803175619	[156]	[140,69,89]	4	hSpCas9	negative selection	1460305
58325025	58325048	18	+	26627737	HeLa	viability after 8 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	-0.06639688739316851	[778]	[373,206,395]	0	hSpCas9	negative selection	1460306
58329089	58329112	18	+	26627737	HeLa	viability after 8 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.32920960388329323	[224]	[87,69,77]	-3	hSpCas9	negative selection	1460307
58333887	58333910	18	-	26627737	HeLa	viability after 8 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	0.3179578608928857	[220]	[159,66,139]	3	hSpCas9	negative selection	1460308
58044687	58044710	18	+	26627737	HeLa	viability after 12 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.7515529278505347	[940]	[161,220,308]	-6	hSpCas9	negative selection	1542618
58315984	58316007	18	+	26627737	HeLa	viability after 12 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.3597795436937329	[309]	[120,276,81]	3	hSpCas9	negative selection	1542619
58322465	58322488	18	+	26627737	HeLa	viability after 12 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	1.2202591950871122	[156]	[215,135,104]	8	hSpCas9	negative selection	1542620
58325025	58325048	18	+	26627737	HeLa	viability after 12 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.14865278572993468	[778]	[282,266,527]	1	hSpCas9	negative selection	1542621
58329089	58329112	18	+	26627737	HeLa	viability after 12 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	0.6567733045783368	[224]	[92,110,237]	5	hSpCas9	negative selection	1542622
58333887	58333910	18	-	26627737	HeLa	viability after 12 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	0.23022524108466946	[220]	[121,114,83]	2	hSpCas9	negative selection	1542623
58044687	58044710	18	+	26627737	HeLa	viability after 15 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.362272009597581	[940]	[395,171,326]	-3	hSpCas9	negative selection	1624933
58315984	58316007	18	+	26627737	HeLa	viability after 15 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.31461729602719407	[309]	[154,60,262]	2	hSpCas9	negative selection	1624934
58322465	58322488	18	+	26627737	HeLa	viability after 15 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-0.04805346485369144	[156]	[55,37,93]	0	hSpCas9	negative selection	1624935
58325025	58325048	18	+	26627737	HeLa	viability after 15 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.4022382282322863	[778]	[381,393,486]	3	hSpCas9	negative selection	1624936
58329089	58329112	18	+	26627737	HeLa	viability after 15 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	0.3341001498044197	[224]	[148,56,141]	3	hSpCas9	negative selection	1624937
58333887	58333910	18	-	26627737	HeLa	viability after 15 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-0.3905384933891566	[220]	[67,43,95]	-3	hSpCas9	negative selection	1624938
58044687	58044710	18	+	26627737	HeLa	viability after 18 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.3708576403431527	[940]	[256,148,326]	-3	hSpCas9	negative selection	1707248
58315984	58316007	18	+	26627737	HeLa	viability after 18 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.2974679525631558	[309]	[99,50,262]	2	hSpCas9	negative selection	1707249
58322465	58322488	18	+	26627737	HeLa	viability after 18 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-0.0402305217523542	[156]	[36,32,93]	0	hSpCas9	negative selection	1707250
58325025	58325048	18	+	26627737	HeLa	viability after 18 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.39531406126132795	[778]	[246,332,486]	3	hSpCas9	negative selection	1707251
58329089	58329112	18	+	26627737	HeLa	viability after 18 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	0.3319650310368561	[224]	[94,52,141]	2	hSpCas9	negative selection	1707252
58333887	58333910	18	-	26627737	HeLa	viability after 18 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-0.4252340717716844	[220]	[41,36,95]	-4	hSpCas9	negative selection	1707253
58044687	58044710	18	+	26627737	HCT116	viability after 6 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	1.6709209840439891	[501]	[113,326]	8	hSpCas9	negative selection	1789563
58315984	58316007	18	+	26627737	HCT116	viability after 6 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.24541324613956061	[313]	[24,76]	1	hSpCas9	negative selection	1789564
58322465	58322488	18	+	26627737	HCT116	viability after 6 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.45275015273751795	[202]	[111,5]	2	hSpCas9	negative selection	1789565
58325025	58325048	18	+	26627737	HCT116	viability after 6 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	-0.6582814140768694	[1328]	[230,77]	-4	hSpCas9	negative selection	1789566
58329089	58329112	18	+	26627737	HCT116	viability after 6 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.05672745509310875	[581]	[18,125]	0	hSpCas9	negative selection	1789567
58333887	58333910	18	-	26627737	HCT116	viability after 6 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-1.6841721738019368	[415]	[49,3]	-7	hSpCas9	negative selection	1789568
58044687	58044710	18	+	26627737	HCT116	viability after 8 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	0.19573949820073278	[572]	[279,408,393]	2	hSpCas9	negative selection	1871878
58315984	58316007	18	+	26627737	HCT116	viability after 8 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.40674195943160685	[194]	[179,104,142]	4	hSpCas9	negative selection	1871879
58322465	58322488	18	+	26627737	HCT116	viability after 8 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-0.2822412784743887	[295]	[107,167,125]	-3	hSpCas9	negative selection	1871880
58325025	58325048	18	+	26627737	HCT116	viability after 8 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.46206165405651933	[493]	[342,378,401]	5	hSpCas9	negative selection	1871881
58329089	58329112	18	+	26627737	HCT116	viability after 8 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.8267104904626882	[257]	[83,114,41]	-8	hSpCas9	negative selection	1871882
58333887	58333910	18	-	26627737	HCT116	viability after 8 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-0.23464730325080707	[214]	[138,83,79]	-3	hSpCas9	negative selection	1871883
58044687	58044710	18	+	26627737	HCT116	viability after 9 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	1.0202877726580568	[501]	[86,417]	7	hSpCas9	negative selection	1954193
58315984	58316007	18	+	26627737	HCT116	viability after 9 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	-0.09211561767173493	[313]	[38,109]	0	hSpCas9	negative selection	1954194
58322465	58322488	18	+	26627737	HCT116	viability after 9 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	1.021604270972805	[202]	[142,83]	7	hSpCas9	negative selection	1954195
58325025	58325048	18	+	26627737	HCT116	viability after 9 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.7551247191099291	[1328]	[651,556]	5	hSpCas9	negative selection	1954196
58329089	58329112	18	+	26627737	HCT116	viability after 9 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-1.7422648495432702	[581]	[65,30]	-8	hSpCas9	negative selection	1954197
58333887	58333910	18	-	26627737	HCT116	viability after 9 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	0.4492246288608742	[415]	[297,35]	3	hSpCas9	negative selection	1954198
58044687	58044710	18	+	26627737	HCT116	viability after 12 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.1709664348467682	[572]	[108,376,332]	-2	hSpCas9	negative selection	2036508
58315984	58316007	18	+	26627737	HCT116	viability after 12 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.4779172214790375	[194]	[157,190,78]	4	hSpCas9	negative selection	2036509
58322465	58322488	18	+	26627737	HCT116	viability after 12 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-1.084676933060459	[295]	[72,111,35]	-8	hSpCas9	negative selection	2036510
58325025	58325048	18	+	26627737	HCT116	viability after 12 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.357797257230556	[493]	[231,460,316]	3	hSpCas9	negative selection	2036511
58329089	58329112	18	+	26627737	HCT116	viability after 12 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.9179022787767527	[257]	[73,67,72]	-7	hSpCas9	negative selection	2036512
58333887	58333910	18	-	26627737	HCT116	viability after 12 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-0.31039128925208304	[214]	[51,99,124]	-3	hSpCas9	negative selection	2036513
58044687	58044710	18	+	26627737	HCT116	viability after 15 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	0.03892256559279661	[572]	[173,544,275]	0	hSpCas9	negative selection	2118823
58315984	58316007	18	+	26627737	HCT116	viability after 15 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.2857850646189085	[194]	[63,221,114]	3	hSpCas9	negative selection	2118824
58322465	58322488	18	+	26627737	HCT116	viability after 15 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-0.4122224553487849	[295]	[172,109,105]	-4	hSpCas9	negative selection	2118825
58325025	58325048	18	+	26627737	HCT116	viability after 15 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.4045178121315217	[493]	[487,338,313]	4	hSpCas9	negative selection	2118826
58329089	58329112	18	+	26627737	HCT116	viability after 15 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.3736204302798811	[257]	[109,71,159]	-4	hSpCas9	negative selection	2118827
58333887	58333910	18	-	26627737	HCT116	viability after 15 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-0.5826821209276842	[214]	[65,68,109]	-6	hSpCas9	negative selection	2118828
58044687	58044710	18	+	26627737	HCT116	viability after 18 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.12541737418705856	[572]	[135,343,276]	-1	hSpCas9	negative selection	2201138
58315984	58316007	18	+	26627737	HCT116	viability after 18 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	-1.14693114776485	[194]	[29,70,23]	-7	hSpCas9	negative selection	2201139
58322465	58322488	18	+	26627737	HCT116	viability after 18 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-0.8572581485485102	[295]	[74,88,71]	-7	hSpCas9	negative selection	2201140
58325025	58325048	18	+	26627737	HCT116	viability after 18 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.5100991735870274	[493]	[426,358,227]	4	hSpCas9	negative selection	2201141
58329089	58329112	18	+	26627737	HCT116	viability after 18 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.955188963688366	[257]	[39,99,49]	-7	hSpCas9	negative selection	2201142
58333887	58333910	18	-	26627737	HCT116	viability after 18 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-0.6303440370980846	[214]	[39,64,97]	-5	hSpCas9	negative selection	2201143
58322442	58322465	18	+	24336569	HL60	viability	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	1.9572163675351637	[45]	[377]	9	hSpCas9	negative selection	2279687
58322449	58322472	18	-	24336569	HL60	viability	AGAAAGTCCTTAAATGTATAGGG	NEDD4L	ENSG00000049759	0.9185358993711035	[114]	[459]	7	hSpCas9	negative selection	2279688
58322465	58322488	18	+	24336569	HL60	viability	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.6776312299882183	[316]	[1072]	6	hSpCas9	negative selection	2279689
58322472	58322495	18	-	24336569	HL60	viability	AGCCTCACCTTCTTGGTCTGAGG	NEDD4L	ENSG00000049759	0.39916174027752416	[300]	[839]	3	hSpCas9	negative selection	2279690
58322479	58322502	18	-	24336569	HL60	viability	ACCCACAAGCCTCACCTTCTTGG	NEDD4L	ENSG00000049759	0.5055968659762579	[457]	[1375]	4	hSpCas9	negative selection	2279691
58323229	58323252	18	+	24336569	HL60	viability	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	-0.2809081889912635	[394]	[687]	-2	hSpCas9	negative selection	2279692
58323310	58323333	18	+	24336569	HL60	viability	CAGTGACCAGAGGGATGACATGG	NEDD4L	ENSG00000049759	-0.025548111375223503	[872]	[1814]	0	hSpCas9	negative selection	2279693
58323316	58323339	18	-	24336569	HL60	viability	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	0.6349627502846567	[855]	[2812]	5	hSpCas9	negative selection	2279694
58324982	58325005	18	+	24336569	HL60	viability	ACTTTATTCCGCAGCATGGATGG	NEDD4L	ENSG00000049759	3.1023330753949736	[22]	[417]	9	hSpCas9	negative selection	2279695
58325007	58325030	18	+	24336569	HL60	viability	AGTTGTTGACTCAAATGACTCGG	NEDD4L	ENSG00000049759	0.7824743497950752	[399]	[1455]	6	hSpCas9	negative selection	2279696
58322442	58322465	18	+	24336569	KBM7	viability	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	1.0499204629219343	[101]	[575]	8	hSpCas9	negative selection	2346864
58322449	58322472	18	-	24336569	KBM7	viability	AGAAAGTCCTTAAATGTATAGGG	NEDD4L	ENSG00000049759	1.1095419337638734	[217]	[1282]	8	hSpCas9	negative selection	2346865
58322465	58322488	18	+	24336569	KBM7	viability	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.6821013848245097	[310]	[1360]	6	hSpCas9	negative selection	2346866
58322472	58322495	18	-	24336569	KBM7	viability	AGCCTCACCTTCTTGGTCTGAGG	NEDD4L	ENSG00000049759	0.5307507998126546	[217]	[858]	5	hSpCas9	negative selection	2346867
58322479	58322502	18	-	24336569	KBM7	viability	ACCCACAAGCCTCACCTTCTTGG	NEDD4L	ENSG00000049759	0.09521384992833415	[566]	[1651]	0	hSpCas9	negative selection	2346868
58323229	58323252	18	+	24336569	KBM7	viability	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	-0.3853508963735414	[362]	[757]	-3	hSpCas9	negative selection	2346869
58323310	58323333	18	+	24336569	KBM7	viability	CAGTGACCAGAGGGATGACATGG	NEDD4L	ENSG00000049759	-0.12359451536758259	[700]	[1754]	-1	hSpCas9	negative selection	2346870
58323316	58323339	18	-	24336569	KBM7	viability	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	-0.1661584101909257	[1162]	[2826]	-1	hSpCas9	negative selection	2346871
58324982	58325005	18	+	24336569	KBM7	viability	ACTTTATTCCGCAGCATGGATGG	NEDD4L	ENSG00000049759	0.6555142964152209	[161]	[695]	6	hSpCas9	negative selection	2346872
58325007	58325030	18	+	24336569	KBM7	viability	AGTTGTTGACTCAAATGACTCGG	NEDD4L	ENSG00000049759	0.42870030564408657	[361]	[1328]	4	hSpCas9	negative selection	2346873
58148359	58148382	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCATGTTGGTCAGGCCGG	NEDD4L	ENSG00000049759	-0.9950505910624323	[34,30]	[4,1]	-6	dCas9-VP64	positive selection	2385334
58062943	58062966	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCCACTGCACTCCAGCCTGGG	NEDD4L	ENSG00000049759	-0.4511660430985071	[55,91]	[10,11]	-2	dCas9-VP64	positive selection	2390538
58371070	58371093	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGCTCTTTCACCCAGGCTAG	NEDD4L	ENSG00000049759	-3.4752685797456295	[670,81]	[9,2]	-9	dCas9-VP64	positive selection	2390657
58127714	58127737	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTTGTAGTCCCAGCTACTCAGG	NEDD4L	ENSG00000049759	-0.8391819250206091	[111,80]	[9,12]	-5	dCas9-VP64	positive selection	2393409
58081410	58081433	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCGTGTTAGCCAGGAAGG	NEDD4L	ENSG00000049759	0.2955844688889684	[184,570]	[130,72]	1	dCas9-VP64	positive selection	2398538
58092934	58092957	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAAGCTCCGCCTCCCAAG	NEDD4L	ENSG00000049759	0.20407356943453547	[198,395]	[107,39]	1	dCas9-VP64	positive selection	2401821
58047119	58047142	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAATGCCCGCTGAAGCAAACGG	NEDD4L	ENSG00000049759	1.9957240012542234	[120,82]	[156,16]	7	dCas9-VP64	positive selection	2402141
58047088	58047111	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCCTGCTAAAATCTTCCATTGG	NEDD4L	ENSG00000049759	0.7286807644238371	[69,158]	[25,57]	3	dCas9-VP64	positive selection	2402142
58047072	58047095	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTATGTGTAAGAAAAACCAATGG	NEDD4L	ENSG00000049759	0.5157192771271553	[14,33]	[6,7]	2	dCas9-VP64	positive selection	2402143
58221374	58221397	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAACAACTGCAGGGAACCTGG	NEDD4L	ENSG00000049759	9.436003695831344	[188,94]	[32262,10263]	9	dCas9-VP64	positive selection	2402144
58221392	58221415	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCCGGGGCCTTATCTCCAGG	NEDD4L	ENSG00000049759	4.949392001415446	[551,812]	[499,9162]	9	dCas9-VP64	positive selection	2402145
58221345	58221368	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTCAAGTGAAGTTCTCAGTGG	NEDD4L	ENSG00000049759	-0.7063587227802253	[177,147]	[16,25]	-4	dCas9-VP64	positive selection	2402146
58149235	58149258	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGGTAACTTGGCAGTCCTGGG	NEDD4L	ENSG00000049759	0.5908029620479195	[37,102]	[22,22]	2	dCas9-VP64	positive selection	2402147
58149189	58149212	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TATCTTATGTGGCGTTATCTGGG	NEDD4L	ENSG00000049759	-0.9812204524998307	[125,735]	[7,91]	-6	dCas9-VP64	positive selection	2402148
58149155	58149178	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTACTGAAGGTGGAGGGCCCTGG	NEDD4L	ENSG00000049759	0.3491237772638449	[26,16]	[6,3]	1	dCas9-VP64	positive selection	2402149
58244786	58244809	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGAAGAATCGCTTGAACCTGAG	NEDD4L	ENSG00000049759	0.25493722011269604	[40,19]	[10,3]	1	dCas9-VP64	positive selection	2412305
58182551	58182574	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCCAGGCTGGAGTGCAGAGG	NEDD4L	ENSG00000049759	-0.49998316673352905	[290,357]	[69,28]	-2	dCas9-VP64	positive selection	2425337
58348589	58348612	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCATCGTGCCCGG	NEDD4L	ENSG00000049759	-2.3680687732448105	[443,16]	[15,1]	-9	dCas9-VP64	positive selection	2440293
58338663	58338686	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGGCTGAAG	NEDD4L	ENSG00000049759	0.17430442440476024	[13,29]	[6,2]	0	dCas9-VP64	positive selection	2446128
58206361	58206384	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCGCTATGTCACCCAGG	NEDD4L	ENSG00000049759	0.6554256480809371	[58,1089]	[28,388]	3	dCas9-VP64	positive selection	2456406
58199501	58199524	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAGCGTGAGCCACCGTGCCTGG	NEDD4L	ENSG00000049759	1.3051580023585738	[14,7]	[5,4]	5	dCas9-VP64	positive selection	2476744
58081257	58081280	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGCCACTGCACTCCAGCCCAG	NEDD4L	ENSG00000049759	-0.533989545843368	[184,280]	[23,46]	-3	dCas9-VP64	positive selection	2477376
58148359	58148382	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCATGTTGGTCAGGCCGG	NEDD4L	ENSG00000049759	-0.9351084987288634	[176,47]	[27,9]	-8	dCas9-VP64	positive selection	2480589
58062943	58062966	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCCACTGCACTCCAGCCTGGG	NEDD4L	ENSG00000049759	-0.10831419915270625	[89,129]	[31,33]	-1	dCas9-VP64	positive selection	2485793
58371070	58371093	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGCTCTTTCACCCAGGCTAG	NEDD4L	ENSG00000049759	0.8980088860596516	[158,118]	[140,31]	6	dCas9-VP64	positive selection	2485912
58127714	58127737	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTTGTAGTCCCAGCTACTCAGG	NEDD4L	ENSG00000049759	1.1377968629765447	[99,72]	[76,47]	7	dCas9-VP64	positive selection	2488664
58081410	58081433	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCGTGTTAGCCAGGAAGG	NEDD4L	ENSG00000049759	1.071805523628855	[383,191]	[227,172]	7	dCas9-VP64	positive selection	2493793
58092934	58092957	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAAGCTCCGCCTCCCAAG	NEDD4L	ENSG00000049759	4.4236004262517	[85,230]	[22,2123]	9	dCas9-VP64	positive selection	2497076
58047119	58047142	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAATGCCCGCTGAAGCAAACGG	NEDD4L	ENSG00000049759	0.07759063490048645	[339,130]	[110,53]	0	dCas9-VP64	positive selection	2497396
58047088	58047111	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCCTGCTAAAATCTTCCATTGG	NEDD4L	ENSG00000049759	0.9324112088911231	[141,317]	[196,90]	6	dCas9-VP64	positive selection	2497397
58047072	58047095	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTATGTGTAAGAAAAACCAATGG	NEDD4L	ENSG00000049759	0.4929265456631494	[36,73]	[18,29]	4	dCas9-VP64	positive selection	2497398
58221374	58221397	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAACAACTGCAGGGAACCTGG	NEDD4L	ENSG00000049759	6.900516565162057	[521,366]	[17141,17711]	9	dCas9-VP64	positive selection	2497399
58221392	58221415	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCCGGGGCCTTATCTCCAGG	NEDD4L	ENSG00000049759	4.57775213432072	[262,143]	[647,2491]	9	dCas9-VP64	positive selection	2497400
58221345	58221368	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTCAAGTGAAGTTCTCAGTGG	NEDD4L	ENSG00000049759	0.2518595306821103	[284,246]	[33,168]	2	dCas9-VP64	positive selection	2497401
58149235	58149258	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGGTAACTTGGCAGTCCTGGG	NEDD4L	ENSG00000049759	1.105809717231555	[88,135]	[108,49]	7	dCas9-VP64	positive selection	2497402
58149189	58149212	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TATCTTATGTGGCGTTATCTGGG	NEDD4L	ENSG00000049759	-0.5982795115589163	[82,159]	[16,33]	-6	dCas9-VP64	positive selection	2497403
58149155	58149178	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTACTGAAGGTGGAGGGCCCTGG	NEDD4L	ENSG00000049759	-1.4264873527556474	[87,90]	[6,12]	-9	dCas9-VP64	positive selection	2497404
58244786	58244809	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGAAGAATCGCTTGAACCTGAG	NEDD4L	ENSG00000049759	-0.6152755658460514	[139,54]	[28,12]	-6	dCas9-VP64	positive selection	2507560
58182551	58182574	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCCAGGCTGGAGTGCAGAGG	NEDD4L	ENSG00000049759	0.5593039216911941	[271,243]	[52,190]	4	dCas9-VP64	positive selection	2520592
58348589	58348612	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCATCGTGCCCGG	NEDD4L	ENSG00000049759	0.42142368151358683	[69,54]	[32,21]	3	dCas9-VP64	positive selection	2535548
58338663	58338686	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGGCTGAAG	NEDD4L	ENSG00000049759	-0.20184825873935663	[30,89]	[7,24]	-2	dCas9-VP64	positive selection	2541383
58206361	58206384	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCGCTATGTCACCCAGG	NEDD4L	ENSG00000049759	0.32671661568011956	[247,62]	[91,37]	2	dCas9-VP64	positive selection	2551661
58199501	58199524	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAGCGTGAGCCACCGTGCCTGG	NEDD4L	ENSG00000049759	1.1554864993418033	[20,247]	[176,21]	7	dCas9-VP64	positive selection	2571999
58081257	58081280	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGCCACTGCACTCCAGCCCAG	NEDD4L	ENSG00000049759	0.47261086320192236	[687,417]	[369,140]	4	dCas9-VP64	positive selection	2572631
58322465	58322488	18	+	27260157	DLD1	viability	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.642338688667761	[]	[]	8	hSpCas9	negative selection	2573826
58149413	58149436	18	+	27260157	DLD1	viability	CGGCAGTGGAAAGTTACCCTTGG	NEDD4L	ENSG00000049759	0.8424720937097	[]	[]	9	hSpCas9	negative selection	2574225
58324982	58325005	18	+	27260157	DLD1	viability	ACTTTATTCCGCAGCATGGATGG	NEDD4L	ENSG00000049759	0.381204253263742	[]	[]	4	hSpCas9	negative selection	2574240
58325007	58325030	18	+	27260157	DLD1	viability	AGTTGTTGACTCAAATGACTCGG	NEDD4L	ENSG00000049759	0.613172716681956	[]	[]	8	hSpCas9	negative selection	2577345
58149352	58149375	18	+	27260157	DLD1	viability	AACCGTGTAGACTGCTTTCCTGG	NEDD4L	ENSG00000049759	-0.468229748808969	[]	[]	-4	hSpCas9	negative selection	2578283
58149442	58149465	18	-	27260157	DLD1	viability	TGAAGAGTATGCGGAAGTCGTGG	NEDD4L	ENSG00000049759	0.503572210602992	[]	[]	8	hSpCas9	negative selection	2584105
58044698	58044721	18	-	27260157	DLD1	viability	GGTGCCACTCACCTCGTCTTCGG	NEDD4L	ENSG00000049759	0.765728370297541	[]	[]	8	hSpCas9	negative selection	2584565
58322472	58322495	18	-	27260157	DLD1	viability	AGCCTCACCTTCTTGGTCTGAGG	NEDD4L	ENSG00000049759	-0.577393355227058	[]	[]	-5	hSpCas9	negative selection	2607857
58322442	58322465	18	+	27260157	DLD1	viability	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	0.0679420468278084	[]	[]	3	hSpCas9	negative selection	2609065
58322479	58322502	18	-	27260157	DLD1	viability	ACCCACAAGCCTCACCTTCTTGG	NEDD4L	ENSG00000049759	1.12308173958059	[]	[]	9	hSpCas9	negative selection	2609510
58323229	58323252	18	+	27260157	DLD1	viability	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	0.458982840633732	[]	[]	7	hSpCas9	negative selection	2617311
58323316	58323339	18	-	27260157	DLD1	viability	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	-0.0632388557641795	[]	[]	0	hSpCas9	negative selection	2618201
58149396	58149419	18	-	27260157	DLD1	viability	CTGCCGGGTGACAAGGTCACAGG	NEDD4L	ENSG00000049759	-0.0993277037178787	[]	[]	0	hSpCas9	negative selection	2619716
58323310	58323333	18	+	27260157	DLD1	viability	CAGTGACCAGAGGGATGACATGG	NEDD4L	ENSG00000049759	1.2231124960624	[]	[]	9	hSpCas9	negative selection	2640830
58322449	58322472	18	-	27260157	DLD1	viability	AGAAAGTCCTTAAATGTATAGGG	NEDD4L	ENSG00000049759	0.286169224540827	[]	[]	4	hSpCas9	negative selection	2641703
58149538	58149561	18	+	27260157	DLD1	viability	GAGACGTCTCGCATTTGAGCAGG	NEDD4L	ENSG00000049759	-0.0255658560891153	[]	[]	0	hSpCas9	negative selection	2642559
58322465	58322488	18	+	27260157	HT1080	viability	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.933556028957354	[]	[]	7	hSpCas9	negative selection	2649956
58149413	58149436	18	+	27260157	HT1080	viability	CGGCAGTGGAAAGTTACCCTTGG	NEDD4L	ENSG00000049759	-0.683086393956141	[]	[]	-8	hSpCas9	negative selection	2650355
58324982	58325005	18	+	27260157	HT1080	viability	ACTTTATTCCGCAGCATGGATGG	NEDD4L	ENSG00000049759	1.0798668415502	[]	[]	8	hSpCas9	negative selection	2650370
58325007	58325030	18	+	27260157	HT1080	viability	AGTTGTTGACTCAAATGACTCGG	NEDD4L	ENSG00000049759	0.0382677563673522	[]	[]	0	hSpCas9	negative selection	2653475
58149352	58149375	18	+	27260157	HT1080	viability	AACCGTGTAGACTGCTTTCCTGG	NEDD4L	ENSG00000049759	-0.635176593473856	[]	[]	-8	hSpCas9	negative selection	2654413
58149442	58149465	18	-	27260157	HT1080	viability	TGAAGAGTATGCGGAAGTCGTGG	NEDD4L	ENSG00000049759	1.2758438763762	[]	[]	9	hSpCas9	negative selection	2660235
58044698	58044721	18	-	27260157	HT1080	viability	GGTGCCACTCACCTCGTCTTCGG	NEDD4L	ENSG00000049759	0.725793891562137	[]	[]	6	hSpCas9	negative selection	2660695
58322472	58322495	18	-	27260157	HT1080	viability	AGCCTCACCTTCTTGGTCTGAGG	NEDD4L	ENSG00000049759	-0.412988962296722	[]	[]	-7	hSpCas9	negative selection	2683987
58322442	58322465	18	+	27260157	HT1080	viability	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	0.250343872880936	[]	[]	2	hSpCas9	negative selection	2685195
58322479	58322502	18	-	27260157	HT1080	viability	ACCCACAAGCCTCACCTTCTTGG	NEDD4L	ENSG00000049759	-0.317690818612733	[]	[]	-7	hSpCas9	negative selection	2685640
58323229	58323252	18	+	27260157	HT1080	viability	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	0.368712683924174	[]	[]	3	hSpCas9	negative selection	2693441
58323316	58323339	18	-	27260157	HT1080	viability	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	-1.36858518415505	[]	[]	-9	hSpCas9	negative selection	2694331
58149396	58149419	18	-	27260157	HT1080	viability	CTGCCGGGTGACAAGGTCACAGG	NEDD4L	ENSG00000049759	0.219920672590925	[]	[]	2	hSpCas9	negative selection	2695846
58323310	58323333	18	+	27260157	HT1080	viability	CAGTGACCAGAGGGATGACATGG	NEDD4L	ENSG00000049759	0.327091868072895	[]	[]	3	hSpCas9	negative selection	2716960
58322449	58322472	18	-	27260157	HT1080	viability	AGAAAGTCCTTAAATGTATAGGG	NEDD4L	ENSG00000049759	0.343324466577649	[]	[]	3	hSpCas9	negative selection	2717833
58149538	58149561	18	+	27260157	HT1080	viability	GAGACGTCTCGCATTTGAGCAGG	NEDD4L	ENSG00000049759	1.02944329713327	[]	[]	8	hSpCas9	negative selection	2718689
58322465	58322488	18	+	27260157	MKN45	viability	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	1.21303867460648	[]	[]	9	hSpCas9	negative selection	2726086
58149413	58149436	18	+	27260157	MKN45	viability	CGGCAGTGGAAAGTTACCCTTGG	NEDD4L	ENSG00000049759	0.25346283352257	[]	[]	5	hSpCas9	negative selection	2726485
58324982	58325005	18	+	27260157	MKN45	viability	ACTTTATTCCGCAGCATGGATGG	NEDD4L	ENSG00000049759	0.52964977109305	[]	[]	6	hSpCas9	negative selection	2726500
58325007	58325030	18	+	27260157	MKN45	viability	AGTTGTTGACTCAAATGACTCGG	NEDD4L	ENSG00000049759	-0.3114107676563	[]	[]	-1	hSpCas9	negative selection	2729605
58149352	58149375	18	+	27260157	MKN45	viability	AACCGTGTAGACTGCTTTCCTGG	NEDD4L	ENSG00000049759	0.395048141205913	[]	[]	6	hSpCas9	negative selection	2730543
58149442	58149465	18	-	27260157	MKN45	viability	TGAAGAGTATGCGGAAGTCGTGG	NEDD4L	ENSG00000049759	0.441978474974423	[]	[]	6	hSpCas9	negative selection	2736365
58044698	58044721	18	-	27260157	MKN45	viability	GGTGCCACTCACCTCGTCTTCGG	NEDD4L	ENSG00000049759	0.832471550950841	[]	[]	8	hSpCas9	negative selection	2736825
58322472	58322495	18	-	27260157	MKN45	viability	AGCCTCACCTTCTTGGTCTGAGG	NEDD4L	ENSG00000049759	0.165250702039368	[]	[]	5	hSpCas9	negative selection	2760117
58322442	58322465	18	+	27260157	MKN45	viability	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	-0.138658851701505	[]	[]	0	hSpCas9	negative selection	2761325
58322479	58322502	18	-	27260157	MKN45	viability	ACCCACAAGCCTCACCTTCTTGG	NEDD4L	ENSG00000049759	1.23024700277819	[]	[]	9	hSpCas9	negative selection	2761770
58323229	58323252	18	+	27260157	MKN45	viability	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	0.604890806366959	[]	[]	7	hSpCas9	negative selection	2769571
58323316	58323339	18	-	27260157	MKN45	viability	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	-0.221823065223438	[]	[]	-1	hSpCas9	negative selection	2770461
58149396	58149419	18	-	27260157	MKN45	viability	CTGCCGGGTGACAAGGTCACAGG	NEDD4L	ENSG00000049759	0.785186174271015	[]	[]	7	hSpCas9	negative selection	2771976
58323310	58323333	18	+	27260157	MKN45	viability	CAGTGACCAGAGGGATGACATGG	NEDD4L	ENSG00000049759	0.59835152075724	[]	[]	7	hSpCas9	negative selection	2793090
58322449	58322472	18	-	27260157	MKN45	viability	AGAAAGTCCTTAAATGTATAGGG	NEDD4L	ENSG00000049759	1.45248984857401	[]	[]	9	hSpCas9	negative selection	2793963
58149538	58149561	18	+	27260157	MKN45	viability	GAGACGTCTCGCATTTGAGCAGG	NEDD4L	ENSG00000049759	1.21570777043751	[]	[]	9	hSpCas9	negative selection	2794819
58322465	58322488	18	+	27260157	RKO	viability	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.624164948333642	[]	[]	3	hSpCas9	negative selection	2802216
58149413	58149436	18	+	27260157	RKO	viability	CGGCAGTGGAAAGTTACCCTTGG	NEDD4L	ENSG00000049759	-0.219916924698217	[]	[]	-1	hSpCas9	negative selection	2802615
58324982	58325005	18	+	27260157	RKO	viability	ACTTTATTCCGCAGCATGGATGG	NEDD4L	ENSG00000049759	0.57212789190799	[]	[]	3	hSpCas9	negative selection	2802630
58325007	58325030	18	+	27260157	RKO	viability	AGTTGTTGACTCAAATGACTCGG	NEDD4L	ENSG00000049759	0.370968846169099	[]	[]	2	hSpCas9	negative selection	2805735
58149352	58149375	18	+	27260157	RKO	viability	AACCGTGTAGACTGCTTTCCTGG	NEDD4L	ENSG00000049759	-0.255124896929689	[]	[]	-1	hSpCas9	negative selection	2806673
58149442	58149465	18	-	27260157	RKO	viability	TGAAGAGTATGCGGAAGTCGTGG	NEDD4L	ENSG00000049759	1.482758524598	[]	[]	9	hSpCas9	negative selection	2812495
58044698	58044721	18	-	27260157	RKO	viability	GGTGCCACTCACCTCGTCTTCGG	NEDD4L	ENSG00000049759	0.260159895482189	[]	[]	1	hSpCas9	negative selection	2812955
58322472	58322495	18	-	27260157	RKO	viability	AGCCTCACCTTCTTGGTCTGAGG	NEDD4L	ENSG00000049759	0.335851175493482	[]	[]	1	hSpCas9	negative selection	2836247
58322442	58322465	18	+	27260157	RKO	viability	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	-0.25296602737143	[]	[]	-1	hSpCas9	negative selection	2837455
58322479	58322502	18	-	27260157	RKO	viability	ACCCACAAGCCTCACCTTCTTGG	NEDD4L	ENSG00000049759	0.119992612864311	[]	[]	0	hSpCas9	negative selection	2837900
58323229	58323252	18	+	27260157	RKO	viability	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	0.916948471889458	[]	[]	8	hSpCas9	negative selection	2845701
58323316	58323339	18	-	27260157	RKO	viability	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	-0.0437882020151371	[]	[]	0	hSpCas9	negative selection	2846591
58149396	58149419	18	-	27260157	RKO	viability	CTGCCGGGTGACAAGGTCACAGG	NEDD4L	ENSG00000049759	0.597131776269068	[]	[]	3	hSpCas9	negative selection	2848106
58323310	58323333	18	+	27260157	RKO	viability	CAGTGACCAGAGGGATGACATGG	NEDD4L	ENSG00000049759	1.07810271720307	[]	[]	9	hSpCas9	negative selection	2869220
58322449	58322472	18	-	27260157	RKO	viability	AGAAAGTCCTTAAATGTATAGGG	NEDD4L	ENSG00000049759	0.987719228701075	[]	[]	9	hSpCas9	negative selection	2870093
58149538	58149561	18	+	27260157	RKO	viability	GAGACGTCTCGCATTTGAGCAGG	NEDD4L	ENSG00000049759	-0.311691097564319	[]	[]	-6	hSpCas9	negative selection	2870949
58322465	58322488	18	+	27260157	SF268	viability	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.702381938516544	[]	[]	8	hSpCas9	negative selection	2878346
58149413	58149436	18	+	27260157	SF268	viability	CGGCAGTGGAAAGTTACCCTTGG	NEDD4L	ENSG00000049759	-0.297245094509929	[]	[]	-2	hSpCas9	negative selection	2878745
58324982	58325005	18	+	27260157	SF268	viability	ACTTTATTCCGCAGCATGGATGG	NEDD4L	ENSG00000049759	0.0526900447240084	[]	[]	0	hSpCas9	negative selection	2878760
58325007	58325030	18	+	27260157	SF268	viability	AGTTGTTGACTCAAATGACTCGG	NEDD4L	ENSG00000049759	0.140959733000757	[]	[]	0	hSpCas9	negative selection	2881865
58149352	58149375	18	+	27260157	SF268	viability	AACCGTGTAGACTGCTTTCCTGG	NEDD4L	ENSG00000049759	-0.00106030896605987	[]	[]	0	hSpCas9	negative selection	2882803
58149442	58149465	18	-	27260157	SF268	viability	TGAAGAGTATGCGGAAGTCGTGG	NEDD4L	ENSG00000049759	1.18366249405327	[]	[]	9	hSpCas9	negative selection	2888625
58044698	58044721	18	-	27260157	SF268	viability	GGTGCCACTCACCTCGTCTTCGG	NEDD4L	ENSG00000049759	0.944524422401104	[]	[]	9	hSpCas9	negative selection	2889085
58322472	58322495	18	-	27260157	SF268	viability	AGCCTCACCTTCTTGGTCTGAGG	NEDD4L	ENSG00000049759	0.168280448635481	[]	[]	0	hSpCas9	negative selection	2912377
58322442	58322465	18	+	27260157	SF268	viability	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	0.633725352821284	[]	[]	8	hSpCas9	negative selection	2913585
58322479	58322502	18	-	27260157	SF268	viability	ACCCACAAGCCTCACCTTCTTGG	NEDD4L	ENSG00000049759	0.803574106572442	[]	[]	8	hSpCas9	negative selection	2914030
58323229	58323252	18	+	27260157	SF268	viability	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	0.696389150479529	[]	[]	8	hSpCas9	negative selection	2921831
58323316	58323339	18	-	27260157	SF268	viability	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	-0.813335388631973	[]	[]	-6	hSpCas9	negative selection	2922721
58149396	58149419	18	-	27260157	SF268	viability	CTGCCGGGTGACAAGGTCACAGG	NEDD4L	ENSG00000049759	0.516770010692735	[]	[]	8	hSpCas9	negative selection	2924236
58323310	58323333	18	+	27260157	SF268	viability	CAGTGACCAGAGGGATGACATGG	NEDD4L	ENSG00000049759	0.210580809687405	[]	[]	3	hSpCas9	negative selection	2945350
58322449	58322472	18	-	27260157	SF268	viability	AGAAAGTCCTTAAATGTATAGGG	NEDD4L	ENSG00000049759	0.494672660516889	[]	[]	7	hSpCas9	negative selection	2946223
58149538	58149561	18	+	27260157	SF268	viability	GAGACGTCTCGCATTTGAGCAGG	NEDD4L	ENSG00000049759	-0.146607703597085	[]	[]	-1	hSpCas9	negative selection	2947079
58329023	58329046	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATCAGACAGATCAACCAGGAGG	NEDD4L	ENSG00000049759	0.09488006590242058	[3,2]	[2,3]	2	hSpCas9	positive selection	3005197
58333827	58333850	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATGACCTCAACCTTGAGGAGGG	NEDD4L	ENSG00000049759	-0.07974928374552359	[3,3]	[3,2]	-1	hSpCas9	positive selection	3005198
58330738	58330761	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCTTGGGAGACCATTTCAGAGG	NEDD4L	ENSG00000049759	0.5442302319551746	[2,2]	[4,2]	9	hSpCas9	positive selection	3005199
58330833	58330856	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.0905516369303484	[4,4]	[4,3]	1	hSpCas9	positive selection	3005200
58329023	58329046	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATCAGACAGATCAACCAGGAGG	NEDD4L	ENSG00000049759	-0.43279890904633966	[3,3]	[3,0]	-6	hSpCas9	positive selection	3073055
58333827	58333850	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATGACCTCAACCTTGAGGAGGG	NEDD4L	ENSG00000049759	0.1813831921954261	[3,3]	[2,2]	3	hSpCas9	positive selection	3073056
58330738	58330761	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCTTGGGAGACCATTTCAGAGG	NEDD4L	ENSG00000049759	0.4042917735533282	[2,2]	[2,2]	7	hSpCas9	positive selection	3073057
58330833	58330856	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.196140802852051	[4,4]	[4,3]	3	hSpCas9	positive selection	3073058
58322465	58322488		+	24336571	A375	resistance to PLX after 7 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-0.9207197663528739	[6,7]	[3,3]	-9	hSpCas9	positive selection	3130250
58323229	58323252		+	24336571	A375	resistance to PLX after 7 days	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	0.08519440362100816	[25,31]	[28,31]	3	hSpCas9	positive selection	3130251
58165833	58165856		+	24336571	A375	resistance to PLX after 7 days	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	-0.09479346300721136	[54,52]	[52,48]	-3	hSpCas9	positive selection	3130252
58245439	58245462		+	24336571	A375	resistance to PLX after 7 days	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	-0.0027869527748576317	[28,33]	[29,32]	0	hSpCas9	positive selection	3130253
58322442	58322465		+	24336571	A375	resistance to PLX after 7 days	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	-0.10860465649093082	[8,9]	[9,7]	-3	hSpCas9	positive selection	3130254
58165837	58165860		-	24336571	A375	resistance to PLX after 7 days	GGCTCCAAAGATGTCCTTTTTGG	NEDD4L	ENSG00000049759	0.05351896722770766	[42,40]	[43,42]	2	hSpCas9	positive selection	3130255
58323316	58323339		-	24336571	A375	resistance to PLX after 7 days	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	-0.1752500457684416	[44,39]	[37,36]	-5	hSpCas9	positive selection	3130256
58245431	58245454		-	24336571	A375	resistance to PLX after 7 days	TACAATGAAAGTTTCACATACGG	NEDD4L	ENSG00000049759	-0.41172822575813983	[35,35]	[25,26]	-9	hSpCas9	positive selection	3130257
58322465	58322488		+	24336571	A375	resistance to PLX after 14 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-0.2788646962138708	[5,5]	[1,1]	-3	hSpCas9	positive selection	3188043
58323229	58323252		+	24336571	A375	resistance to PLX after 14 days	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	0.6613017812660242	[30,24]	[21,18]	6	hSpCas9	positive selection	3188044
58165833	58165856		+	24336571	A375	resistance to PLX after 14 days	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.6467238272114102	[61,63]	[39,51]	6	hSpCas9	positive selection	3188045
58245439	58245462		+	24336571	A375	resistance to PLX after 14 days	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	-0.49403226103009645	[28,30]	[9,8]	-6	hSpCas9	positive selection	3188046
58322442	58322465		+	24336571	A375	resistance to PLX after 14 days	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	-0.5504285487874256	[11,13]	[2,3]	-6	hSpCas9	positive selection	3188047
58165837	58165860		-	24336571	A375	resistance to PLX after 14 days	GGCTCCAAAGATGTCCTTTTTGG	NEDD4L	ENSG00000049759	-0.35606132303255134	[37,44]	[15,12]	-4	hSpCas9	positive selection	3188048
58323316	58323339		-	24336571	A375	resistance to PLX after 14 days	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	0.1935240525599662	[42,32]	[17,21]	2	hSpCas9	positive selection	3188049
58245431	58245454		-	24336571	A375	resistance to PLX after 14 days	TACAATGAAAGTTTCACATACGG	NEDD4L	ENSG00000049759	-1.1035848958629024	[25,40]	[6,6]	-9	hSpCas9	positive selection	3188050
58322465	58322488		+	24336571	A375	viability after 7 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-0.7855847158392265	[13]	[6,7]	-8	hSpCas9	negative selection	3245836
58323229	58323252		+	24336571	A375	viability after 7 days	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	0.2666805378121182	[24]	[25,31]	4	hSpCas9	negative selection	3245837
58165833	58165856		+	24336571	A375	viability after 7 days	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.2530123041813075	[47]	[54,52]	4	hSpCas9	negative selection	3245838
58245439	58245462		+	24336571	A375	viability after 7 days	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	-0.6179840460110848	[50]	[28,33]	-7	hSpCas9	negative selection	3245839
58322442	58322465		+	24336571	A375	viability after 7 days	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	-0.06408321116067656	[10]	[8,9]	-1	hSpCas9	negative selection	3245840
58165837	58165860		-	24336571	A375	viability after 7 days	GGCTCCAAAGATGTCCTTTTTGG	NEDD4L	ENSG00000049759	0.038481414016552584	[42]	[42,40]	0	hSpCas9	negative selection	3245841
58323316	58323339		-	24336571	A375	viability after 7 days	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	-0.5098908762916776	[63]	[44,39]	-6	hSpCas9	negative selection	3245842
58245431	58245454		-	24336571	A375	viability after 7 days	TACAATGAAAGTTTCACATACGG	NEDD4L	ENSG00000049759	-0.2516269268600757	[44]	[35,35]	-4	hSpCas9	negative selection	3245843
58322465	58322488		+	24336571	A375	viability after 14 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-1.0863484835262562	[13]	[5,5]	-8	hSpCas9	negative selection	3303629
58323229	58323252		+	24336571	A375	viability after 14 days	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	0.21903425012267808	[24]	[30,24]	3	hSpCas9	negative selection	3303630
58165833	58165856		+	24336571	A375	viability after 14 days	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.4730554022039024	[47]	[61,63]	6	hSpCas9	negative selection	3303631
58245439	58245462		+	24336571	A375	viability after 14 days	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	-0.6760530959153361	[50]	[28,30]	-7	hSpCas9	negative selection	3303632
58322442	58322465		+	24336571	A375	viability after 14 days	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	0.3540535577824082	[10]	[11,13]	4	hSpCas9	negative selection	3303633
58165837	58165860		-	24336571	A375	viability after 14 days	GGCTCCAAAGATGTCCTTTTTGG	NEDD4L	ENSG00000049759	0.03554001070470525	[42]	[37,44]	0	hSpCas9	negative selection	3303634
58323316	58323339		-	24336571	A375	viability after 14 days	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	-0.6656186644801048	[63]	[42,32]	-7	hSpCas9	negative selection	3303635
58245431	58245454		-	24336571	A375	viability after 14 days	TACAATGAAAGTTTCACATACGG	NEDD4L	ENSG00000049759	-0.3561914902369956	[44]	[25,40]	-4	hSpCas9	negative selection	3303636
58245463	58245486	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	-0.8616148612776724	[277,277]	[0,0]	-6	hSpCas9	positive selection	3381404
58165803	58165826	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.25732621144583506	[127,127]	[0,0]	1	hSpCas9	positive selection	3381405
58248908	58248931	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	-1.9906013019977504	[607,607]	[0,0]	-9	hSpCas9	positive selection	3381406
58329022	58329045	18	+	26780180	HT29	viability (Avana library 4 designs)	CATCAGACAGATCAACCAGGAGG	NEDD4L	ENSG00000049759	1.74944378133783	[]	[]	6	hSpCas9	negative selection	3443029
58333827	58333850	18	-	26780180	HT29	viability (Avana library 4 designs)	CATGACCTCAACCTTGAGGAGGG	NEDD4L	ENSG00000049759	0.541627330510051	[]	[]	2	hSpCas9	negative selection	3443030
58330737	58330760	18	+	26780180	HT29	viability (Avana library 4 designs)	GCCTTGGGAGACCATTTCAGAGG	NEDD4L	ENSG00000049759	2.06341013460301	[]	[]	7	hSpCas9	negative selection	3443031
58330833	58330856	18	-	26780180	HT29	viability (Avana library 4 designs)	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	-0.502267221990625	[]	[]	-7	hSpCas9	negative selection	3443032
58329022	58329045	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATCAGACAGATCAACCAGGAGG	NEDD4L	ENSG00000049759	-6.86634060590618	[]	[]	-6	hSpCas9	negative selection	3534521
58330833	58330856	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	-4.24240816411917	[]	[]	-5	hSpCas9	negative selection	3534522
58330737	58330760	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTTGGGAGACCATTTCAGAGG	NEDD4L	ENSG00000049759	-4.22914307162639	[]	[]	-5	hSpCas9	negative selection	3534523
58333827	58333850	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATGACCTCAACCTTGAGGAGGG	NEDD4L	ENSG00000049759	-4.40873744073799	[]	[]	-5	hSpCas9	negative selection	3534524
58343065	58343088	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGTTATGATCAATGAAGAAGGG	NEDD4L	ENSG00000049759	-11.7792179655539	[]	[]	-8	hSpCas9	negative selection	3534525
58329003	58329026	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	1.69896199693786	[]	[]	2	hSpCas9	negative selection	3534526
58329022	58329045	18	+	26780180	A375	viability (Avana lentiGuide)	CATCAGACAGATCAACCAGGAGG	NEDD4L	ENSG00000049759	13.3541499119038	[]	[]	7	hSpCas9	negative selection	3643180
58330833	58330856	18	-	26780180	A375	viability (Avana lentiGuide)	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	25.9258936019766	[]	[]	9	hSpCas9	negative selection	3643181
58330737	58330760	18	+	26780180	A375	viability (Avana lentiGuide)	GCCTTGGGAGACCATTTCAGAGG	NEDD4L	ENSG00000049759	27.8001088386076	[]	[]	9	hSpCas9	negative selection	3643182
58333827	58333850	18	-	26780180	A375	viability (Avana lentiGuide)	CATGACCTCAACCTTGAGGAGGG	NEDD4L	ENSG00000049759	14.0455851498916	[]	[]	7	hSpCas9	negative selection	3643183
58343065	58343088	18	-	26780180	A375	viability (Avana lentiGuide)	GTGTTATGATCAATGAAGAAGGG	NEDD4L	ENSG00000049759	26.0072910930642	[]	[]	9	hSpCas9	negative selection	3643184
58329003	58329026	18	-	26780180	A375	viability (Avana lentiGuide)	GATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	7.8465826694463	[]	[]	6	hSpCas9	negative selection	3643185
58329022	58329045	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCAGACAGATCAACCAGGAGG	NEDD4L	ENSG00000049759	-0.5875566064214325	[4]	[3,1]	-7	hSpCas9	positive selection	3751839
58330833	58330856	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	-0.7627126832788594	[5]	[3,1]	-8	hSpCas9	positive selection	3751840
58330737	58330760	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTTGGGAGACCATTTCAGAGG	NEDD4L	ENSG00000049759	-0.1673143960400402	[4]	[3,3]	-3	hSpCas9	positive selection	3751841
58333827	58333850	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGACCTCAACCTTGAGGAGGG	NEDD4L	ENSG00000049759	0.028426927906868304	[5]	[5,4]	0	hSpCas9	positive selection	3751842
58343065	58343088	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGTTATGATCAATGAAGAAGGG	NEDD4L	ENSG00000049759	-1.022606848348674	[9]	[4,2]	-9	hSpCas9	positive selection	3751843
58329003	58329026	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	0.23478161282854915	[6]	[7,6]	6	hSpCas9	positive selection	3751844
58329022	58329045	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCAGACAGATCAACCAGGAGG	NEDD4L	ENSG00000049759	-0.5229547424366706	[4]	[1,3]	-6	hSpCas9	positive selection	3860446
58330833	58330856	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	-0.8938602621371872	[5]	[2,1]	-8	hSpCas9	positive selection	3860447
58330737	58330760	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTTGGGAGACCATTTCAGAGG	NEDD4L	ENSG00000049759	-1.4145846305995848	[4]	[1,0]	-9	hSpCas9	positive selection	3860448
58333827	58333850	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGACCTCAACCTTGAGGAGGG	NEDD4L	ENSG00000049759	-1.009985378591626	[5]	[2,1]	-8	hSpCas9	positive selection	3860449
58343065	58343088	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGTTATGATCAATGAAGAAGGG	NEDD4L	ENSG00000049759	-0.7117430789297885	[5]	[1,3]	-7	hSpCas9	positive selection	3860450
58329003	58329026	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	-0.23422153902000054	[6]	[4,4]	-3	hSpCas9	positive selection	3860451
58165803	58165826	18	+	26780180	A375	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.505215229031774	[]	[]	1	hSpCas9	negative selection	3971762
58165833	58165856	18	+	26780180	A375	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	-0.331690956297154	[]	[]	-8	hSpCas9	negative selection	3971763
58245439	58245462	18	+	26780180	A375	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	1.07916758050447	[]	[]	5	hSpCas9	negative selection	3971764
58248908	58248931	18	-	26780180	A375	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	-0.263537570719059	[]	[]	-7	hSpCas9	negative selection	3971765
58248894	58248917	18	+	26780180	A375	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.112863688215949	[]	[]	0	hSpCas9	negative selection	3971766
58245463	58245486	18	+	26780180	A375	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	1.63832203815394	[]	[]	8	hSpCas9	negative selection	3971767
58165803	58165826	18	+	26780180	HT29	viability (GeCKOv2 library)	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	1.19193752940457	[]	[]	6	hSpCas9	negative selection	4079728
58165833	58165856	18	+	26780180	HT29	viability (GeCKOv2 library)	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	-0.350227468244137	[]	[]	-8	hSpCas9	negative selection	4079729
58245439	58245462	18	+	26780180	HT29	viability (GeCKOv2 library)	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.727455761799605	[]	[]	3	hSpCas9	negative selection	4079730
58248908	58248931	18	-	26780180	HT29	viability (GeCKOv2 library)	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	-0.172473282243226	[]	[]	-5	hSpCas9	negative selection	4079731
58248894	58248917	18	+	26780180	HT29	viability (GeCKOv2 library)	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.725637725008904	[]	[]	2	hSpCas9	negative selection	4079732
58245463	58245486	18	+	26780180	HT29	viability (GeCKOv2 library)	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	1.46175219920438	[]	[]	7	hSpCas9	negative selection	4079733
58322465	58322488	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-0.5109730127833461	[2]	[1,0]	-8	hSpCas9	positive selection	4154887
58323229	58323252	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	0.2185043614195774	[5]	[3,4]	5	hSpCas9	positive selection	4154888
58165833	58165856	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.35570274553319703	[5]	[4,5]	8	hSpCas9	positive selection	4154889
58245439	58245462	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	-0.07401717865637275	[5]	[3,3]	-2	hSpCas9	positive selection	4154890
58322442	58322465	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	0.1981864738458468	[3]	[2,1]	5	hSpCas9	positive selection	4154891
58165837	58165860	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCTCCAAAGATGTCCTTTTTGG	NEDD4L	ENSG00000049759	0.11677992347850397	[5]	[3,3]	3	hSpCas9	positive selection	4154892
58323316	58323339	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	0.1043437120699725	[5]	[3,4]	2	hSpCas9	positive selection	4154893
58245431	58245454	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACAATGAAAGTTTCACATACGG	NEDD4L	ENSG00000049759	0.039646861052675675	[4]	[3,2]	1	hSpCas9	positive selection	4154894
58322465	58322488	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.6597130876111642	[3]	[5,4,3,0]	4	hSpCas9	positive selection	4218909
58323229	58323252	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGTCATAAGTCTCGAGTTAAGG	NEDD4L	ENSG00000049759	0.05981680588710721	[3]	[3,2,1,0]	0	hSpCas9	positive selection	4218910
58165833	58165856	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.6939426333897598	[5]	[3,4,3,3]	4	hSpCas9	positive selection	4218911
58245439	58245462	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.7538294231767011	[5]	[3,4,2,4]	5	hSpCas9	positive selection	4218912
58322442	58322465	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAGCGACCCTATACATTTAAGG	NEDD4L	ENSG00000049759	1.1841310816628772	[2]	[0,1,0,3]	8	hSpCas9	positive selection	4218913
58165837	58165860	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCTCCAAAGATGTCCTTTTTGG	NEDD4L	ENSG00000049759	0.876453307743916	[4]	[4,3,3,3]	6	hSpCas9	positive selection	4218914
58323316	58323339	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTACCTCCATGTCATCCCTCTGG	NEDD4L	ENSG00000049759	-0.25986573154721837	[5]	[1,0,4,0]	-4	hSpCas9	positive selection	4218915
58245431	58245454	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACAATGAAAGTTTCACATACGG	NEDD4L	ENSG00000049759	0.697013380699452	[5]	[2,3,1,4]	4	hSpCas9	positive selection	4218916
58245439	58245462	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	-0.3491703386553553	[2]	[1,0]	-6	hSpCas9	positive selection	4285260
58165833	58165856	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.5823142420555835	[3]	[5,4]	9	hSpCas9	positive selection	4285261
58248894	58248917	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.03330761189427589	[1]	[1,0]	0	hSpCas9	positive selection	4285262
58245463	58245486	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	-0.09914738618144708	[3]	[3,1]	-2	hSpCas9	positive selection	4349519
58165803	58165826	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.3257858379238714	[2]	[4,1]	6	hSpCas9	positive selection	4349520
58248908	58248931	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.43895478077956573	[4]	[4,4]	8	hSpCas9	positive selection	4349521
58341728	58341750	18	+	27760321	OCIAML3	viability	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.04122478820677267	[948,832]	[547,933]	0	hSpCas9	negative selection	4421830
58342912	58342934	18	+	27760321	OCIAML3	viability	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	0.003412868629378618	[690,576]	[372,653]	0	hSpCas9	negative selection	4421831
58325157	58325179	18	-	27760321	OCIAML3	viability	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	-0.027286352807523007	[427,354]	[220,400]	0	hSpCas9	negative selection	4421832
58329003	58329025	18	-	27760321	OCIAML3	viability	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	0.47594225339488216	[597,605]	[563,778]	6	hSpCas9	negative selection	4421833
58329101	58329123	18	-	27760321	OCIAML3	viability	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.7878705185333483	[739,642]	[864,1017]	8	hSpCas9	negative selection	4421834
58341728	58341750	18	+	27760321	OCIAML2	viability	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.06462310534620386	[948,832]	[717,647]	-1	hSpCas9	negative selection	4505293
58342912	58342934	18	+	27760321	OCIAML2	viability	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	0.4154314525613222	[690,576]	[647,724]	5	hSpCas9	negative selection	4505294
58325157	58325179	18	-	27760321	OCIAML2	viability	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	-1.1746672061609897	[427,354]	[143,133]	-8	hSpCas9	negative selection	4505295
58329003	58329025	18	-	27760321	OCIAML2	viability	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	0.5198974880276337	[597,605]	[665,746]	7	hSpCas9	negative selection	4505296
58329101	58329123	18	-	27760321	OCIAML2	viability	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.07925590385196146	[739,642]	[491,717]	1	hSpCas9	negative selection	4505297
58341728	58341750	18	+	27760321	MV411	viability	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.7675060792532347	[948,832]	[1067,894]	5	hSpCas9	negative selection	4588756
58342912	58342934	18	+	27760321	MV411	viability	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	1.0360674854367269	[690,576]	[1122,450]	7	hSpCas9	negative selection	4588757
58325157	58325179	18	-	27760321	MV411	viability	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	0.9587103731756002	[427,354]	[415,625]	7	hSpCas9	negative selection	4588758
58329003	58329025	18	-	27760321	MV411	viability	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	-0.38741752541283364	[597,605]	[385,182]	-3	hSpCas9	negative selection	4588759
58329101	58329123	18	-	27760321	MV411	viability	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.36756303101222043	[739,642]	[679,447]	2	hSpCas9	negative selection	4588760
58341728	58341750	18	+	27760321	HL60	viability	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.04497303815852616	[948,832]	[688,719]	0	hSpCas9	negative selection	4672219
58342912	58342934	18	+	27760321	HL60	viability	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	0.32181602860267877	[690,576]	[434,866]	4	hSpCas9	negative selection	4672220
58325157	58325179	18	-	27760321	HL60	viability	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	-1.614129252831094	[427,354]	[120,85]	-8	hSpCas9	negative selection	4672221
58329003	58329025	18	-	27760321	HL60	viability	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	-0.36797004400671096	[597,605]	[415,346]	-4	hSpCas9	negative selection	4672222
58329101	58329123	18	-	27760321	HL60	viability	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	-0.07612996056533561	[739,642]	[567,498]	-1	hSpCas9	negative selection	4672223
58341728	58341750	18	+	27760321	HT1080	viability	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.4786191841614845	[832,649]	[137,292]	-2	hSpCas9	negative selection	4755682
58342912	58342934	18	+	27760321	HT1080	viability	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	1.8908160197438304	[576,449]	[559,975]	8	hSpCas9	negative selection	4755683
58325157	58325179	18	-	27760321	HT1080	viability	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	1.8699842131174127	[354,276]	[441,479]	8	hSpCas9	negative selection	4755684
58329003	58329025	18	-	27760321	HT1080	viability	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	0.07626358520721399	[605,472]	[238,212]	0	hSpCas9	negative selection	4755685
58329101	58329123	18	-	27760321	HT1080	viability	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.584876284602839	[642,501]	[364,316]	3	hSpCas9	negative selection	4755686
58341728	58341750	18	+	27760321	HT29	viability after 7 days	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.0997095050326583	[832,649]	[1024,1056,613]	-1	hSpCas9	negative selection	4839145
58342912	58342934	18	+	27760321	HT29	viability after 7 days	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	-0.07667784898696545	[576,449]	[442,780,626]	-1	hSpCas9	negative selection	4839146
58325157	58325179	18	-	27760321	HT29	viability after 7 days	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	0.19443631319168392	[354,276]	[573,288,543]	3	hSpCas9	negative selection	4839147
58329003	58329025	18	-	27760321	HT29	viability after 7 days	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	-0.4592941559053241	[605,472]	[596,614,319]	-6	hSpCas9	negative selection	4839148
58329101	58329123	18	-	27760321	HT29	viability after 7 days	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.5473048649714201	[642,501]	[1102,1451,686]	8	hSpCas9	negative selection	4839149
58341728	58341750	18	+	27760321	HT29	viability after 25 days	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.33386965445193884	[832,649]	[1055,848,1324]	3	hSpCas9	negative selection	4922608
58342912	58342934	18	+	27760321	HT29	viability after 25 days	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	0.32712755579216546	[576,449]	[616,877,717]	3	hSpCas9	negative selection	4922609
58325157	58325179	18	-	27760321	HT29	viability after 25 days	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	0.5087024851874677	[354,276]	[539,303,715]	5	hSpCas9	negative selection	4922610
58329003	58329025	18	-	27760321	HT29	viability after 25 days	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	-0.10964535749166388	[605,472]	[541,612,558]	-1	hSpCas9	negative selection	4922611
58329101	58329123	18	-	27760321	HT29	viability after 25 days	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.5621367565102897	[642,501]	[845,920,1156]	6	hSpCas9	negative selection	4922612
58341728	58341750	18	+	27760321	HT29	viability after 22 days	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.36049450850105336	[832,649]	[1209,944,1143]	4	hSpCas9	negative selection	5006071
58342912	58342934	18	+	27760321	HT29	viability after 22 days	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	-0.13687819930018347	[576,449]	[406,591,624]	-1	hSpCas9	negative selection	5006072
58325157	58325179	18	-	27760321	HT29	viability after 22 days	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	0.47582167156460786	[354,276]	[325,590,612]	5	hSpCas9	negative selection	5006073
58329003	58329025	18	-	27760321	HT29	viability after 22 days	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	-0.21524152259798113	[605,472]	[579,552,476]	-2	hSpCas9	negative selection	5006074
58329101	58329123	18	-	27760321	HT29	viability after 22 days	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.7103119928047343	[642,501]	[880,1299,1072]	7	hSpCas9	negative selection	5006075
58341728	58341750	18	+	27760321	HT29	viability after 19 days	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.38052404444379984	[832,649]	[1241,855,1222]	3	hSpCas9	negative selection	5089534
58342912	58342934	18	+	27760321	HT29	viability after 19 days	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	0.4889700914799098	[576,449]	[892,971,621]	5	hSpCas9	negative selection	5089535
58325157	58325179	18	-	27760321	HT29	viability after 19 days	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	0.6534265585677824	[354,276]	[496,190,992]	6	hSpCas9	negative selection	5089536
58329003	58329025	18	-	27760321	HT29	viability after 19 days	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	-0.5174419904046058	[605,472]	[612,564,144]	-4	hSpCas9	negative selection	5089537
58329101	58329123	18	-	27760321	HT29	viability after 19 days	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.24150766748466923	[642,501]	[642,729,928]	2	hSpCas9	negative selection	5089538
58341728	58341750	18	+	27760321	HT29	viability after 16 days	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.04123389430084634	[832,649]	[786,756,1012]	0	hSpCas9	negative selection	5172997
58342912	58342934	18	+	27760321	HT29	viability after 16 days	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	-0.13115143789150457	[576,449]	[650,391,545]	-1	hSpCas9	negative selection	5172998
58325157	58325179	18	-	27760321	HT29	viability after 16 days	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	0.08543358375887157	[354,276]	[395,268,464]	0	hSpCas9	negative selection	5172999
58329003	58329025	18	-	27760321	HT29	viability after 16 days	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	-0.7717421081869315	[605,472]	[318,325,412]	-6	hSpCas9	negative selection	5173000
58329101	58329123	18	-	27760321	HT29	viability after 16 days	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.6703498000836268	[642,501]	[869,936,1238]	7	hSpCas9	negative selection	5173001
58341728	58341750	18	+	27760321	HT29	viability after 13 days	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.04453032550468805	[832,649]	[1075,562,1013]	0	hSpCas9	negative selection	5256460
58342912	58342934	18	+	27760321	HT29	viability after 13 days	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	-0.02318333846087628	[576,449]	[324,607,811]	0	hSpCas9	negative selection	5256461
58325157	58325179	18	-	27760321	HT29	viability after 13 days	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	-0.07435255527089257	[354,276]	[365,237,434]	-1	hSpCas9	negative selection	5256462
58329003	58329025	18	-	27760321	HT29	viability after 13 days	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	-0.4730297785822698	[605,472]	[456,552,348]	-5	hSpCas9	negative selection	5256463
58329101	58329123	18	-	27760321	HT29	viability after 13 days	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.36473252309148685	[642,501]	[1005,888,680]	4	hSpCas9	negative selection	5256464
58341728	58341750	18	+	27760321	HT29	viability after 10 days	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.30103968903332956	[832,649]	[869,814,574]	-4	hSpCas9	negative selection	5339923
58342912	58342934	18	+	27760321	HT29	viability after 10 days	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	0.10910849881299933	[576,449]	[476,1021,586]	1	hSpCas9	negative selection	5339924
58325157	58325179	18	-	27760321	HT29	viability after 10 days	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	0.31743987063296747	[354,276]	[615,338,514]	4	hSpCas9	negative selection	5339925
58329003	58329025	18	-	27760321	HT29	viability after 10 days	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	-0.6649940987435723	[605,472]	[382,454,436]	-7	hSpCas9	negative selection	5339926
58329101	58329123	18	-	27760321	HT29	viability after 10 days	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.44748941043475976	[642,501]	[1065,1251,621]	6	hSpCas9	negative selection	5339927
58341728	58341750	18	+	27760321	MOLM13	viability	AATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.0029521969758241617	[948,832]	[444,547]	0	hSpCas9	negative selection	5423386
58342912	58342934	18	+	27760321	MOLM13	viability	AAGGACTCACCCGTACGTCGGG	NEDD4L	ENSG00000049759	-0.07055830218073172	[690,576]	[167,484]	0	hSpCas9	negative selection	5423387
58325157	58325179	18	-	27760321	MOLM13	viability	ATCACACGGTACTCACATCAGG	NEDD4L	ENSG00000049759	0.18450458149065121	[427,354]	[250,248]	1	hSpCas9	negative selection	5423388
58329003	58329025	18	-	27760321	MOLM13	viability	ATGTTATTGTCCGACTCCGAGG	NEDD4L	ENSG00000049759	0.41570017572847084	[597,605]	[712,234]	3	hSpCas9	negative selection	5423389
58329101	58329123	18	-	27760321	MOLM13	viability	GGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	1.6861186029489896	[739,642]	[756,1673]	9	hSpCas9	negative selection	5423390
58044537	58044560	18	+	27661255	K562	viability	GGCAGGGCGTGCGCAGGGTAGGG	NEDD4L	ENSG00000049759	-0.11696284941865964	[449,795]	[483,428]	-4	dCas9-KRAB	negative selection	5496148
58149548	58149571	18	+	27661255	K562	viability	GCATTTGAGCAGGTAACACTCGG	NEDD4L	ENSG00000049759	0.32066449836451927	[281,297]	[281,294]	9	dCas9-KRAB	negative selection	5496149
58044620	58044643	18	-	27661255	K562	viability	GGGGTCTGAGGCGCTCCCAGCGG	NEDD4L	ENSG00000049759	0.06633885999773817	[868,706]	[728,603]	2	dCas9-KRAB	negative selection	5496150
58044741	58044764	18	-	27661255	K562	viability	GGCGCGGGATAGGAACTCCCCGG	NEDD4L	ENSG00000049759	-0.08169482212632667	[643,665]	[539,454]	-3	dCas9-KRAB	negative selection	5496151
58245439	58245462	18	+	27260156	BXPC3	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.664192106295961	[215]	[285,458,304,382]	9	hSpCas9	negative selection	5557720
58165833	58165856	18	+	27260156	BXPC3	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.8292745876856064	[801]	[1132,1440,1565,1903]	9	hSpCas9	negative selection	5557721
58248894	58248917	18	+	27260156	BXPC3	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5550570675675683	[135]	[200,189,159,294]	9	hSpCas9	negative selection	5557722
58245463	58245486	18	+	27260156	BXPC3	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.3322267465067854	[658]	[826,847,847,956]	7	hSpCas9	negative selection	5621979
58165803	58165826	18	+	27260156	BXPC3	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.29894176418470825	[395]	[415,411,655,576]	6	hSpCas9	negative selection	5621980
58248908	58248931	18	-	27260156	BXPC3	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.3747813478745936	[1073]	[1268,1456,1489,1641]	7	hSpCas9	negative selection	5621981
58245439	58245462	18	+	27260156	A673	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.4498785291751265	[215]	[377,228,392,425]	8	hSpCas9	negative selection	5678971
58165833	58165856	18	+	27260156	A673	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.7163232984527795	[801]	[1760,1591,1520,1465]	9	hSpCas9	negative selection	5678972
58248894	58248917	18	+	27260156	A673	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5275316600499798	[135]	[275,142,302,224]	9	hSpCas9	negative selection	5678973
58245463	58245486	18	+	27260156	A673	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.09477017990174963	[658]	[905,651,812,1029]	2	hSpCas9	negative selection	5743230
58165803	58165826	18	+	27260156	A673	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.3160490028242323	[395]	[746,443,491,712]	7	hSpCas9	negative selection	5743231
58248908	58248931	18	-	27260156	A673	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.45056749807759156	[1073]	[2147,1642,1634,1662]	8	hSpCas9	negative selection	5743232
58245439	58245462	18	+	27260156	A375	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.042208364525704756	[215]	[177,366,206,295]	0	hSpCas9	negative selection	5800222
58165833	58165856	18	+	27260156	A375	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.7408572651503321	[801]	[1636,1991,1384,1329]	9	hSpCas9	negative selection	5800223
58248894	58248917	18	+	27260156	A375	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.6719213994279514	[135]	[339,313,164,206]	8	hSpCas9	negative selection	5800224
58245463	58245486	18	+	27260156	A375	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	-0.5194757637631332	[658]	[428,519,613,574]	-6	hSpCas9	negative selection	5864481
58165803	58165826	18	+	27260156	A375	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.249068490743098	[395]	[515,626,448,607]	3	hSpCas9	negative selection	5864482
58248908	58248931	18	-	27260156	A375	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.7792643565087667	[1073]	[2411,1968,2594,1662]	9	hSpCas9	negative selection	5864483
58245439	58245462	18	+	27260156	COLO741	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.29848050909742563	[215]	[341,409,270]	6	hSpCas9	negative selection	5921473
58165833	58165856	18	+	27260156	COLO741	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.5711641909098711	[801]	[1546,1510,1508]	9	hSpCas9	negative selection	5921474
58248894	58248917	18	+	27260156	COLO741	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.598902119690718	[135]	[292,298,203]	9	hSpCas9	negative selection	5921475
58245463	58245486	18	+	27260156	COLO741	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.24021615468174573	[658]	[1121,1042,838]	5	hSpCas9	negative selection	5985732
58165803	58165826	18	+	27260156	COLO741	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	-0.02250128392226214	[395]	[562,469,467]	0	hSpCas9	negative selection	5985733
58248908	58248931	18	-	27260156	COLO741	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.5479697958015552	[1073]	[2050,1653,2290]	9	hSpCas9	negative selection	5985734
58245439	58245462	18	+	27260156	CAL120	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.6029704323207727	[215]	[383,544,293]	8	hSpCas9	negative selection	6042724
58165833	58165856	18	+	27260156	CAL120	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	1.0148444022049752	[801]	[2133,1706,2221]	9	hSpCas9	negative selection	6042725
58248894	58248917	18	+	27260156	CAL120	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.6250826522381414	[135]	[397,225,180]	8	hSpCas9	negative selection	6042726
58245463	58245486	18	+	27260156	CAL120	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.043140482988702766	[658]	[1146,703,730]	0	hSpCas9	negative selection	6106983
58165803	58165826	18	+	27260156	CAL120	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.04852166473652944	[395]	[492,680,354]	0	hSpCas9	negative selection	6106984
58248908	58248931	18	-	27260156	CAL120	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.4983000355520013	[1073]	[2389,1892,1462]	7	hSpCas9	negative selection	6106985
58245439	58245462	18	+	27260156	CADOES1	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.5944758563287809	[215]	[322,332,262,293]	8	hSpCas9	negative selection	6163975
58165833	58165856	18	+	27260156	CADOES1	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.6911246930369354	[801]	[1116,1326,1211,1159]	9	hSpCas9	negative selection	6163976
58248894	58248917	18	+	27260156	CADOES1	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5364157357309445	[135]	[169,175,199,187]	8	hSpCas9	negative selection	6163977
58245463	58245486	18	+	27260156	CADOES1	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	-0.19205112137412073	[658]	[528,549,456,612]	-3	hSpCas9	negative selection	6228234
58165803	58165826	18	+	27260156	CADOES1	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.3751886316727345	[395]	[326,540,393,655]	6	hSpCas9	negative selection	6228235
58248908	58248931	18	-	27260156	CADOES1	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.7059878892118661	[1073]	[1424,1615,1597,1888]	9	hSpCas9	negative selection	6228236
58245439	58245462	18	+	27260156	EWS502	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.46991241344277546	[215]	[209,401,349,313]	7	hSpCas9	negative selection	6285226
58165833	58165856	18	+	27260156	EWS502	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.7159332867131879	[801]	[998,1881,1213,1514]	9	hSpCas9	negative selection	6285227
58248894	58248917	18	+	27260156	EWS502	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5735864127880292	[135]	[219,184,149,307]	8	hSpCas9	negative selection	6285228
58245463	58245486	18	+	27260156	EWS502	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.25548498608854353	[658]	[664,853,734,1113]	4	hSpCas9	negative selection	6349485
58165803	58165826	18	+	27260156	EWS502	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.5412059960596507	[395]	[485,628,633,711]	8	hSpCas9	negative selection	6349486
58248908	58248931	18	-	27260156	EWS502	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.5070041377928747	[1073]	[1465,1775,1544,1688]	8	hSpCas9	negative selection	6349487
58245439	58245462	18	+	27260156	EW8	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.7177182586733792	[215]	[253,350,235,314]	9	hSpCas9	negative selection	6406477
58165833	58165856	18	+	27260156	EW8	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.7349458626833872	[801]	[1149,1237,917,1053]	9	hSpCas9	negative selection	6406478
58248894	58248917	18	+	27260156	EW8	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.7542652831171766	[135]	[195,221,182,143]	9	hSpCas9	negative selection	6406479
58245463	58245486	18	+	27260156	EW8	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.3983155186745535	[658]	[1214,598,453,643]	7	hSpCas9	negative selection	6470736
58165803	58165826	18	+	27260156	EW8	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.3432080351890822	[395]	[535,426,274,425]	6	hSpCas9	negative selection	6470737
58248908	58248931	18	-	27260156	EW8	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.537926444173088	[1073]	[1291,1597,902,1323]	8	hSpCas9	negative selection	6470738
58245439	58245462	18	+	27260156	CORL105	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.5474493695507089	[215]	[292,372,474,350]	8	hSpCas9	negative selection	6527728
58165833	58165856	18	+	27260156	CORL105	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.6311297962475754	[801]	[1332,1465,1596,1437]	9	hSpCas9	negative selection	6527729
58248894	58248917	18	+	27260156	CORL105	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5362228587787901	[135]	[149,251,286,239]	8	hSpCas9	negative selection	6527730
58245463	58245486	18	+	27260156	CORL105	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	-0.10417551251140472	[658]	[765,532,833,760]	-2	hSpCas9	negative selection	6591987
58165803	58165826	18	+	27260156	CORL105	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.26295297916725324	[395]	[535,589,589,512]	5	hSpCas9	negative selection	6591988
58248908	58248931	18	-	27260156	CORL105	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.3441141712783573	[1073]	[1558,1589,1857,1416]	6	hSpCas9	negative selection	6591989
58245439	58245462	18	+	27260156	HS294T	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.6524591358213111	[215]	[91,119,119,209]	8	hSpCas9	negative selection	6648979
58165833	58165856	18	+	27260156	HS294T	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.5483734855019534	[801]	[482,365,462,509]	7	hSpCas9	negative selection	6648980
58248894	58248917	18	+	27260156	HS294T	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.523705028625365	[135]	[27,133,45,100]	7	hSpCas9	negative selection	6648981
58245463	58245486	18	+	27260156	HS294T	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.08558857926623253	[658]	[331,212,238,296]	1	hSpCas9	negative selection	6713238
58165803	58165826	18	+	27260156	HS294T	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.13559624700453152	[395]	[156,176,165,173]	1	hSpCas9	negative selection	6713239
58248908	58248931	18	-	27260156	HS294T	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.516241822354113	[1073]	[530,646,570,635]	7	hSpCas9	negative selection	6713240
58245439	58245462	18	+	27260156	HCC44	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.7748926535573804	[215]	[313,321,802,303]	9	hSpCas9	negative selection	6770230
58165833	58165856	18	+	27260156	HCC44	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.7192482726967827	[801]	[1377,1541,1692,1368]	9	hSpCas9	negative selection	6770231
58248894	58248917	18	+	27260156	HCC44	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5267539591593446	[135]	[180,291,144,238]	8	hSpCas9	negative selection	6770232
58245463	58245486	18	+	27260156	HCC44	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.4100284386797477	[658]	[1006,822,979,1160]	6	hSpCas9	negative selection	6834489
58165803	58165826	18	+	27260156	HCC44	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.13194256565660312	[395]	[678,379,542,401]	2	hSpCas9	negative selection	6834490
58248908	58248931	18	-	27260156	HCC44	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.4821270645431879	[1073]	[2117,1397,1487,1809]	7	hSpCas9	negative selection	6834491
58245439	58245462	18	+	27260156	G402	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.5533721662970731	[215]	[394,264,434,441]	7	hSpCas9	negative selection	6891481
58165833	58165856	18	+	27260156	G402	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	1.090609660564858	[801]	[2726,2434,1779,1526]	9	hSpCas9	negative selection	6891482
58248894	58248917	18	+	27260156	G402	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	1.264605750880679	[135]	[373,302,144,744]	9	hSpCas9	negative selection	6891483
58245463	58245486	18	+	27260156	G402	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	-0.1316597350862735	[658]	[822,689,603,821]	-2	hSpCas9	negative selection	6955740
58165803	58165826	18	+	27260156	G402	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.2677032529429182	[395]	[531,598,659,529]	3	hSpCas9	negative selection	6955741
58248908	58248931	18	-	27260156	G402	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.8971731201571758	[1073]	[3183,2119,2288,2257]	9	hSpCas9	negative selection	6955742
58245439	58245462	18	+	27260156	L33	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	1.0723203745471752	[215]	[405,161,337,478]	9	hSpCas9	negative selection	7012732
58165833	58165856	18	+	27260156	L33	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.24010373271739172	[801]	[866,437,609,884]	5	hSpCas9	negative selection	7012733
58248894	58248917	18	+	27260156	L33	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5553691951200663	[135]	[99,45,145,355]	9	hSpCas9	negative selection	7012734
58245463	58245486	18	+	27260156	L33	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	-0.05797132394581972	[658]	[569,242,454,646]	-1	hSpCas9	negative selection	7076991
58165803	58165826	18	+	27260156	L33	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.02939380449970644	[395]	[483,159,189,436]	0	hSpCas9	negative selection	7076992
58248908	58248931	18	-	27260156	L33	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.11340143839707406	[1073]	[1051,469,761,1237]	2	hSpCas9	negative selection	7076993
58245439	58245462	18	+	27260156	K562	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.39075625517941337	[215]	[396,241,326,70]	5	hSpCas9	negative selection	7133983
58165833	58165856	18	+	27260156	K562	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.8414661286260935	[801]	[1410,1105,1569,1038]	9	hSpCas9	negative selection	7133984
58248894	58248917	18	+	27260156	K562	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.6247097604999603	[135]	[433,122,115,97]	7	hSpCas9	negative selection	7133985
58245463	58245486	18	+	27260156	K562	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.28912502029856146	[658]	[771,849,689,571]	3	hSpCas9	negative selection	7198242
58165803	58165826	18	+	27260156	K562	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.28730195490624855	[395]	[463,589,402,284]	3	hSpCas9	negative selection	7198243
58248908	58248931	18	-	27260156	K562	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.1998742688938886	[1073]	[1331,1116,767,1168]	2	hSpCas9	negative selection	7198244
58245439	58245462	18	+	27260156	HT29	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.37772596340644315	[215]	[451,328,241,345]	7	hSpCas9	negative selection	7255234
58165833	58165856	18	+	27260156	HT29	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.663883272344023	[801]	[1257,1777,1654,1481]	9	hSpCas9	negative selection	7255235
58248894	58248917	18	+	27260156	HT29	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5675092140409657	[135]	[229,277,173,291]	9	hSpCas9	negative selection	7255236
58245463	58245486	18	+	27260156	HT29	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.40032308085538604	[658]	[940,1519,902,906]	7	hSpCas9	negative selection	7319493
58165803	58165826	18	+	27260156	HT29	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.20805499050852405	[395]	[622,480,541,570]	4	hSpCas9	negative selection	7319494
58248908	58248931	18	-	27260156	HT29	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.6400843250180013	[1073]	[2388,2062,2022,1717]	9	hSpCas9	negative selection	7319495
58245439	58245462	18	+	27260156	MHHES1	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.8075573583275364	[215]	[572,544,483,179]	9	hSpCas9	negative selection	7376485
58165833	58165856	18	+	27260156	MHHES1	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.6545798902144851	[801]	[1537,1611,1368,1216]	9	hSpCas9	negative selection	7376486
58248894	58248917	18	+	27260156	MHHES1	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.7057942736721641	[135]	[281,216,406,119]	9	hSpCas9	negative selection	7376487
58245463	58245486	18	+	27260156	MHHES1	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.2530617270387717	[658]	[1024,1089,942,571]	4	hSpCas9	negative selection	7440744
58165803	58165826	18	+	27260156	MHHES1	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.43646426790813475	[395]	[650,739,653,418]	7	hSpCas9	negative selection	7440745
58248908	58248931	18	-	27260156	MHHES1	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.5705780026465965	[1073]	[2113,2033,1912,1270]	8	hSpCas9	negative selection	7440746
58245439	58245462	18	+	27260156	MEWO	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.2184851820354936	[215]	[247,196,262]	5	hSpCas9	negative selection	7497736
58165833	58165856	18	+	27260156	MEWO	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.5581042134954363	[801]	[1158,988,1176]	9	hSpCas9	negative selection	7497737
58248894	58248917	18	+	27260156	MEWO	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.8435826658253559	[135]	[334,144,225]	9	hSpCas9	negative selection	7497738
58245463	58245486	18	+	27260156	MEWO	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.1265794738900009	[658]	[733,646,649]	3	hSpCas9	negative selection	7561995
58165803	58165826	18	+	27260156	MEWO	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.246748620492215	[395]	[516,370,445]	5	hSpCas9	negative selection	7561996
58248908	58248931	18	-	27260156	MEWO	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.3731076738655361	[1073]	[1434,1228,1265]	7	hSpCas9	negative selection	7561997
58245439	58245462	18	+	27260156	LNCAPCLONEFGC	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.26423316255298646	[215]	[166,300,276,197]	4	hSpCas9	negative selection	7618987
58165833	58165856	18	+	27260156	LNCAPCLONEFGC	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	1.005955822731218	[801]	[1447,1189,1687,1560]	9	hSpCas9	negative selection	7618988
58248894	58248917	18	+	27260156	LNCAPCLONEFGC	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.6795146685780264	[135]	[231,135,193,229]	9	hSpCas9	negative selection	7618989
58245463	58245486	18	+	27260156	LNCAPCLONEFGC	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	-0.13606542785233527	[658]	[319,511,529,814]	-2	hSpCas9	negative selection	7683246
58165803	58165826	18	+	27260156	LNCAPCLONEFGC	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.281958843290945	[395]	[341,345,657,438]	4	hSpCas9	negative selection	7683247
58248908	58248931	18	-	27260156	LNCAPCLONEFGC	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.6809688138720074	[1073]	[1647,1566,1574,1447]	9	hSpCas9	negative selection	7683248
58245439	58245462	18	+	27260156	PANC0327	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.6135196565577627	[215]	[692,144,192,194]	8	hSpCas9	negative selection	7740238
58165833	58165856	18	+	27260156	PANC0327	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.6667163692279082	[801]	[1163,1037,1520,815]	8	hSpCas9	negative selection	7740239
58248894	58248917	18	+	27260156	PANC0327	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	1.53059138449984	[135]	[319,281,264,534]	9	hSpCas9	negative selection	7740240
58245463	58245486	18	+	27260156	PANC0327	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.7252663710689042	[658]	[1370,616,903,1056]	9	hSpCas9	negative selection	7804497
58165803	58165826	18	+	27260156	PANC0327	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.40542599112232003	[395]	[768,248,302,594]	6	hSpCas9	negative selection	7804498
58248908	58248931	18	-	27260156	PANC0327	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.6140546990783868	[1073]	[1487,1429,1632,1295]	8	hSpCas9	negative selection	7804499
58245439	58245462	18	+	27260156	NCIH2009	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.5864661340184489	[215]	[546,465,363]	7	hSpCas9	negative selection	7861489
58165833	58165856	18	+	27260156	NCIH2009	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.5509954458320218	[801]	[2055,1592,1355]	7	hSpCas9	negative selection	7861490
58248894	58248917	18	+	27260156	NCIH2009	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5100011377388045	[135]	[346,182,297]	7	hSpCas9	negative selection	7861491
58245463	58245486	18	+	27260156	NCIH2009	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.03436572781244229	[658]	[924,866,1032]	0	hSpCas9	negative selection	7925748
58165803	58165826	18	+	27260156	NCIH2009	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.37336428403433963	[395]	[806,645,714]	5	hSpCas9	negative selection	7925749
58248908	58248931	18	-	27260156	NCIH2009	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.5244419623966208	[1073]	[2459,2103,1967]	7	hSpCas9	negative selection	7925750
58245439	58245462	18	+	27260156	NCIH1373	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.9038895749534032	[215]	[803,188,478,109]	8	hSpCas9	negative selection	7982740
58165833	58165856	18	+	27260156	NCIH1373	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.8593059079782052	[801]	[2243,1348,1818,314]	8	hSpCas9	negative selection	7982741
58248894	58248917	18	+	27260156	NCIH1373	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.8002466192240505	[135]	[465,84,317,62]	7	hSpCas9	negative selection	7982742
58245463	58245486	18	+	27260156	NCIH1373	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	-0.043237365076692014	[658]	[566,553,993,193]	0	hSpCas9	negative selection	8046999
58165803	58165826	18	+	27260156	NCIH1373	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.4981768477527341	[395]	[563,511,879,141]	5	hSpCas9	negative selection	8047000
58248908	58248931	18	-	27260156	NCIH1373	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	1.0129278604768142	[1073]	[3126,2010,1577,842]	8	hSpCas9	negative selection	8047001
58245439	58245462	18	+	27260156	PATU8902	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.29144195697492037	[215]	[642,359,295,160]	3	hSpCas9	negative selection	8103991
58165833	58165856	18	+	27260156	PATU8902	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	1.3663898733224538	[801]	[3100,3109,2324,3131]	9	hSpCas9	negative selection	8103992
58248894	58248917	18	+	27260156	PATU8902	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	1.1549091980088786	[135]	[187,142,614,725]	9	hSpCas9	negative selection	8103993
58245463	58245486	18	+	27260156	PATU8902	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.5419697606451308	[658]	[1168,1544,1218,1447]	5	hSpCas9	negative selection	8168250
58165803	58165826	18	+	27260156	PATU8902	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.5987856076883218	[395]	[854,806,767,932]	6	hSpCas9	negative selection	8168251
58248908	58248931	18	-	27260156	PATU8902	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	1.1473541142639494	[1073]	[3727,3491,2246,4128]	9	hSpCas9	negative selection	8168252
58245439	58245462	18	+	27260156	PANC1	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.7303950992972637	[215]	[328,296,393,218]	9	hSpCas9	negative selection	8225242
58165833	58165856	18	+	27260156	PANC1	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.9516290090091718	[801]	[1227,1464,1548,1129]	9	hSpCas9	negative selection	8225243
58248894	58248917	18	+	27260156	PANC1	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.45688291783446777	[135]	[133,120,218,157]	7	hSpCas9	negative selection	8225244
58245463	58245486	18	+	27260156	PANC1	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.2415297553886503	[658]	[573,800,772,564]	4	hSpCas9	negative selection	8289501
58165803	58165826	18	+	27260156	PANC1	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.39236880511804445	[395]	[565,502,410,326]	6	hSpCas9	negative selection	8289502
58248908	58248931	18	-	27260156	PANC1	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.49209518747287695	[1073]	[1254,1747,1218,1075]	7	hSpCas9	negative selection	8289503
58245439	58245462	18	+	27260156	PANC0813	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	1.2936878399599712	[215]	[481,610,403,956]	9	hSpCas9	negative selection	8346493
58165833	58165856	18	+	27260156	PANC0813	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.497199795599338	[801]	[1666,1139,1239,1301]	7	hSpCas9	negative selection	8346494
58248894	58248917	18	+	27260156	PANC0813	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5323105260849526	[135]	[186,320,224,188]	8	hSpCas9	negative selection	8346495
58245463	58245486	18	+	27260156	PANC0813	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.2574003458399754	[658]	[1087,1128,796,711]	4	hSpCas9	negative selection	8410752
58165803	58165826	18	+	27260156	PANC0813	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.2500641316410166	[395]	[636,573,452,554]	4	hSpCas9	negative selection	8410753
58248908	58248931	18	-	27260156	PANC0813	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.37484079116768143	[1073]	[1745,1611,1632,1563]	6	hSpCas9	negative selection	8410754
58245439	58245462	18	+	27260156	RDES	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.17593976523052213	[215]	[257,219,329,324]	3	hSpCas9	negative selection	8467744
58165833	58165856	18	+	27260156	RDES	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.7548976968146336	[801]	[1302,1285,1641,2117]	9	hSpCas9	negative selection	8467745
58248894	58248917	18	+	27260156	RDES	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5136404938445132	[135]	[208,244,273,148]	7	hSpCas9	negative selection	8467746
58245463	58245486	18	+	27260156	RDES	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	-0.03943140338703316	[658]	[597,764,593,1037]	0	hSpCas9	negative selection	8532003
58165803	58165826	18	+	27260156	RDES	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.4585384688532532	[395]	[571,472,790,689]	7	hSpCas9	negative selection	8532004
58248908	58248931	18	-	27260156	RDES	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.6451762452467182	[1073]	[1482,1805,2198,2367]	9	hSpCas9	negative selection	8532005
58245439	58245462	18	+	27260156	PC3	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.38681068581243394	[215]	[193,223,462,329]	7	hSpCas9	negative selection	8588995
58165833	58165856	18	+	27260156	PC3	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.5651026492790981	[801]	[863,941,2291,1083]	9	hSpCas9	negative selection	8588996
58248894	58248917	18	+	27260156	PC3	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.6819813267430703	[135]	[223,117,465,124]	9	hSpCas9	negative selection	8588997
58245463	58245486	18	+	27260156	PC3	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.20563918268263526	[658]	[521,705,1281,749]	4	hSpCas9	negative selection	8653254
58165803	58165826	18	+	27260156	PC3	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.030126290731914696	[395]	[251,378,728,407]	0	hSpCas9	negative selection	8653255
58248908	58248931	18	-	27260156	PC3	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.06679717825351572	[1073]	[837,1094,1489,1205]	1	hSpCas9	negative selection	8653256
58245439	58245462	18	+	27260156	PATU8988T	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.5406580157216183	[215]	[405,193,145,473]	8	hSpCas9	negative selection	8710246
58165833	58165856	18	+	27260156	PATU8988T	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	1.0591607897004902	[801]	[1743,1682,1269,1786]	9	hSpCas9	negative selection	8710247
58248894	58248917	18	+	27260156	PATU8988T	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	-0.2517961107269444	[135]	[119,129,128,59]	-4	hSpCas9	negative selection	8710248
58245463	58245486	18	+	27260156	PATU8988T	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.3013576369266737	[658]	[619,615,956,939]	5	hSpCas9	negative selection	8774505
58165803	58165826	18	+	27260156	PATU8988T	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.32381101849964145	[395]	[390,504,485,540]	5	hSpCas9	negative selection	8774506
58248908	58248931	18	-	27260156	PATU8988T	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.39968723542563	[1073]	[1455,1117,1582,1285]	6	hSpCas9	negative selection	8774507
58245439	58245462	18	+	27260156	T47D	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.4935687090357157	[215]	[365,312,389,350]	8	hSpCas9	negative selection	8831497
58165833	58165856	18	+	27260156	T47D	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.7093842752928871	[801]	[1401,1724,1458,1506]	9	hSpCas9	negative selection	8831498
58248894	58248917	18	+	27260156	T47D	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.46519917693002144	[135]	[201,245,176,248]	8	hSpCas9	negative selection	8831499
58245463	58245486	18	+	27260156	T47D	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.23567061715157167	[658]	[978,832,966,839]	5	hSpCas9	negative selection	8895756
58165803	58165826	18	+	27260156	T47D	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.44409095468767146	[395]	[571,703,555,673]	8	hSpCas9	negative selection	8895757
58248908	58248931	18	-	27260156	T47D	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.5106429740645224	[1073]	[1627,1722,1748,2042]	9	hSpCas9	negative selection	8895758
58245439	58245462	18	+	27260156	SU8686	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.6777707988614479	[215]	[281,270,505,326]	9	hSpCas9	negative selection	8952748
58165833	58165856	18	+	27260156	SU8686	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.7663569009941719	[801]	[1214,1142,1461,1678]	9	hSpCas9	negative selection	8952749
58248894	58248917	18	+	27260156	SU8686	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.5832255682847192	[135]	[289,136,169,207]	8	hSpCas9	negative selection	8952750
58245463	58245486	18	+	27260156	SU8686	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.07999436345124711	[658]	[733,593,818,607]	1	hSpCas9	negative selection	9017007
58165803	58165826	18	+	27260156	SU8686	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.17064115817730308	[395]	[413,349,466,569]	3	hSpCas9	negative selection	9017008
58248908	58248931	18	-	27260156	SU8686	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.4187749071087994	[1073]	[1299,1338,1430,1679]	7	hSpCas9	negative selection	9017009
58245439	58245462	18	+	27260156	SKES1	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.31556117284711394	[215]	[318,215,261,272]	6	hSpCas9	negative selection	9073999
58165833	58165856	18	+	27260156	SKES1	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.47040255141273113	[801]	[1197,1073,1175,994]	8	hSpCas9	negative selection	9074000
58248894	58248917	18	+	27260156	SKES1	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.6328528822762167	[135]	[191,241,230,178]	9	hSpCas9	negative selection	9074001
58245463	58245486	18	+	27260156	SKES1	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	-0.08036289375914091	[658]	[526,773,559,624]	-2	hSpCas9	negative selection	9138258
58165803	58165826	18	+	27260156	SKES1	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.312397436901356	[395]	[510,585,492,392]	6	hSpCas9	negative selection	9138259
58248908	58248931	18	-	27260156	SKES1	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.1839200217628265	[1073]	[1273,1319,1186,1107]	4	hSpCas9	negative selection	9138260
58245439	58245462	18	+	27260156	TOV112D	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.330616642416626	[215]	[292,267,163,360]	6	hSpCas9	negative selection	9195250
58165833	58165856	18	+	27260156	TOV112D	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.5916759628987999	[801]	[1324,1562,1115,939]	9	hSpCas9	negative selection	9195251
58248894	58248917	18	+	27260156	TOV112D	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.6530635750418958	[135]	[373,269,75,164]	9	hSpCas9	negative selection	9195252
58245463	58245486	18	+	27260156	TOV112D	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.02395040388735703	[658]	[671,888,617,560]	0	hSpCas9	negative selection	9259509
58165803	58165826	18	+	27260156	TOV112D	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.6740070120427137	[395]	[620,640,557,708]	9	hSpCas9	negative selection	9259510
58248908	58248931	18	-	27260156	TOV112D	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.4776650776985829	[1073]	[1139,1953,1803,1181]	8	hSpCas9	negative selection	9259511
58245439	58245462	18	+	27260156	TC71	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.6270624601532202	[215]	[376,317,289,452]	9	hSpCas9	negative selection	9316501
58165833	58165856	18	+	27260156	TC71	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.5782394100741307	[801]	[1290,1399,1151,1295]	9	hSpCas9	negative selection	9316502
58248894	58248917	18	+	27260156	TC71	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.262905377525416	[135]	[199,144,168,185]	6	hSpCas9	negative selection	9316503
58245463	58245486	18	+	27260156	TC71	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.14975914335475793	[658]	[559,748,921,911]	4	hSpCas9	negative selection	9380760
58165803	58165826	18	+	27260156	TC71	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.24281835856698106	[395]	[493,458,429,636]	6	hSpCas9	negative selection	9380761
58248908	58248931	18	-	27260156	TC71	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.4155587837915309	[1073]	[1493,1532,1515,1604]	8	hSpCas9	negative selection	9380762
58245439	58245462	18	+	27260156	TC32	viability	GAAACTTTCATTGTACGTAGCGG	NEDD4L	ENSG00000049759	0.5160956070275662	[215]	[265,257,399,250]	8	hSpCas9	negative selection	9437752
58165833	58165856	18	+	27260156	TC32	viability	CTCGCCAAAAAGGACATCTTTGG	NEDD4L	ENSG00000049759	0.751891178259375	[801]	[1250,920,1436,1571]	9	hSpCas9	negative selection	9437753
58248894	58248917	18	+	27260156	TC32	viability	TCCAGACACTGAACCCAAAATGG	NEDD4L	ENSG00000049759	0.6325092268908805	[135]	[160,189,108,318]	9	hSpCas9	negative selection	9437754
58245463	58245486	18	+	27260156	TC32	viability	TGAGAATAGAGAACTTGCTTTGG	NEDD4L	ENSG00000049759	0.20833986237664914	[658]	[593,714,1005,557]	4	hSpCas9	negative selection	9502011
58165803	58165826	18	+	27260156	TC32	viability	CTCAGAGTAAAAGTTGTTTCTGG	NEDD4L	ENSG00000049759	0.28524129097113765	[395]	[460,211,693,560]	5	hSpCas9	negative selection	9502012
58248908	58248931	18	-	27260156	TC32	viability	TAAAATTCTTCATTCCATTTTGG	NEDD4L	ENSG00000049759	0.6827753911905581	[1073]	[1539,1432,1938,1600]	9	hSpCas9	negative selection	9502013
58044687	58044710	18	+	27869803	HPAFII	viability after 27 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	0.7451024025903066	[403]	[409,310,NaN]	6	hSpCas9	negative selection	9564819
58315984	58316007	18	+	27869803	HPAFII	viability after 27 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	-0.1041284053516347	[183]	[17,149,NaN]	-1	hSpCas9	negative selection	9564820
58322465	58322488	18	+	27869803	HPAFII	viability after 27 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-0.8218211490664359	[172]	[57,45,NaN]	-5	hSpCas9	negative selection	9564821
58325025	58325048	18	+	27869803	HPAFII	viability after 27 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.48673284217066337	[510]	[286,450,NaN]	4	hSpCas9	negative selection	9564822
58329089	58329112	18	+	27869803	HPAFII	viability after 27 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.537037610976929	[208]	[60,87,NaN]	-4	hSpCas9	negative selection	9564823
58333887	58333910	18	-	27869803	HPAFII	viability after 27 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-0.7005776152977701	[187]	[56,63,NaN]	-5	hSpCas9	negative selection	9564824
58044687	58044710	18	+	27869803	HPAFII	viability after 15 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	0.3132130622478717	[403]	[573,517,NaN]	3	hSpCas9	negative selection	9647268
58315984	58316007	18	+	27869803	HPAFII	viability after 15 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	-0.675582263835845	[183]	[26,183,NaN]	-6	hSpCas9	negative selection	9647269
58322465	58322488	18	+	27869803	HPAFII	viability after 15 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.28076417353220834	[172]	[289,185,NaN]	3	hSpCas9	negative selection	9647270
58325025	58325048	18	+	27869803	HPAFII	viability after 15 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.31520737659031695	[510]	[612,726,NaN]	3	hSpCas9	negative selection	9647271
58329089	58329112	18	+	27869803	HPAFII	viability after 15 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.6118171364499401	[208]	[154,141,NaN]	-6	hSpCas9	negative selection	9647272
58333887	58333910	18	-	27869803	HPAFII	viability after 15 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-0.40624874604429595	[187]	[112,176,NaN]	-4	hSpCas9	negative selection	9647273
58044687	58044710	18	+	27869803	ASPC1	viability after 36 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	0.40541968013957064	[1213]	[738,638,368]	4	hSpCas9	negative selection	9729717
58315984	58316007	18	+	27869803	ASPC1	viability after 36 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.7924186497149539	[395]	[236,185,280]	7	hSpCas9	negative selection	9729718
58322465	58322488	18	+	27869803	ASPC1	viability after 36 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	1.0348226522205657	[322]	[221,342,145]	8	hSpCas9	negative selection	9729719
58325025	58325048	18	+	27869803	ASPC1	viability after 36 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.9381353922986998	[1168]	[524,1437,432]	8	hSpCas9	negative selection	9729720
58329089	58329112	18	+	27869803	ASPC1	viability after 36 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	1.2787651686386667	[343]	[236,631,55]	9	hSpCas9	negative selection	9729721
58333887	58333910	18	-	27869803	ASPC1	viability after 36 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	0.04486900982417863	[338]	[130,123,112]	0	hSpCas9	negative selection	9729722
58044687	58044710	18	+	27869803	PATU8988S	viability after 35 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.07027033795087123	[982]	[412,340,NaN]	0	hSpCas9	negative selection	9812166
58315984	58316007	18	+	27869803	PATU8988S	viability after 35 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	1.9173278608631372	[441]	[630,713,NaN]	9	hSpCas9	negative selection	9812167
58322465	58322488	18	+	27869803	PATU8988S	viability after 35 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.33602034924265456	[363]	[206,162,NaN]	4	hSpCas9	negative selection	9812168
58325025	58325048	18	+	27869803	PATU8988S	viability after 35 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.30874115894427057	[1140]	[435,702,NaN]	3	hSpCas9	negative selection	9812169
58329089	58329112	18	+	27869803	PATU8988S	viability after 35 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	0.7577161309977175	[364]	[272,223,NaN]	7	hSpCas9	negative selection	9812170
58333887	58333910	18	-	27869803	PATU8988S	viability after 35 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	0.8299139024314686	[383]	[236,312,NaN]	8	hSpCas9	negative selection	9812171
58044687	58044710	18	+	27869803	PATU8988S	viability after 31 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	-0.32439434864862227	[982]	[294,335,NaN]	-4	hSpCas9	negative selection	9894615
58315984	58316007	18	+	27869803	PATU8988S	viability after 31 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	1.4248142045787553	[441]	[382,587,NaN]	9	hSpCas9	negative selection	9894616
58322465	58322488	18	+	27869803	PATU8988S	viability after 31 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	0.0726352412579847	[363]	[138,169,NaN]	0	hSpCas9	negative selection	9894617
58325025	58325048	18	+	27869803	PATU8988S	viability after 31 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.21557727993396414	[1140]	[394,697,NaN]	2	hSpCas9	negative selection	9894618
58329089	58329112	18	+	27869803	PATU8988S	viability after 31 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	0.8042747712364504	[364]	[225,289,NaN]	8	hSpCas9	negative selection	9894619
58333887	58333910	18	-	27869803	PATU8988S	viability after 31 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	0.40572821958755567	[383]	[219,180,NaN]	5	hSpCas9	negative selection	9894620
58044687	58044710	18	+	27869803	HPAFII	viability after 35 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	0.9810578093989948	[403]	[414,390,NaN]	6	hSpCas9	negative selection	9977064
58315984	58316007	18	+	27869803	HPAFII	viability after 35 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.6476479547784887	[183]	[1,307,NaN]	4	hSpCas9	negative selection	9977065
58322465	58322488	18	+	27869803	HPAFII	viability after 35 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-1.0561548822630975	[172]	[43,39,NaN]	-5	hSpCas9	negative selection	9977066
58325025	58325048	18	+	27869803	HPAFII	viability after 35 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.8578910863257874	[510]	[164,810,NaN]	5	hSpCas9	negative selection	9977067
58329089	58329112	18	+	27869803	HPAFII	viability after 35 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-1.180054257155808	[208]	[25,69,NaN]	-6	hSpCas9	negative selection	9977068
58333887	58333910	18	-	27869803	HPAFII	viability after 35 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-0.7550994904862756	[187]	[14,102,NaN]	-4	hSpCas9	negative selection	9977069
58044687	58044710	18	+	27869803	HPAFII	viability after 31 days	CTATGGACTTTCCGAAGACGAGG	NEDD4L	ENSG00000049759	0.5899959333221911	[403]	[369,309,NaN]	4	hSpCas9	negative selection	10059513
58315984	58316007	18	+	27869803	HPAFII	viability after 31 days	ACGAGACGACTTCCTGGGCCAGG	NEDD4L	ENSG00000049759	0.7783460153187858	[183]	[0,368,NaN]	5	hSpCas9	negative selection	10059514
58322465	58322488	18	+	27869803	HPAFII	viability after 31 days	ACTTTCTCCTCAGACCAAGAAGG	NEDD4L	ENSG00000049759	-0.07288664310271786	[172]	[87,96,NaN]	0	hSpCas9	negative selection	10059515
58325025	58325048	18	+	27869803	HPAFII	viability after 31 days	CTCGGCTTCTCAGCACCAAGAGG	NEDD4L	ENSG00000049759	0.6633529262136837	[510]	[223,704,NaN]	5	hSpCas9	negative selection	10059516
58329089	58329112	18	+	27869803	HPAFII	viability after 31 days	TTGGAGCCCGAGCCCTCGGAGGG	NEDD4L	ENSG00000049759	-0.5595503486940145	[208]	[47,113,NaN]	-4	hSpCas9	negative selection	10059517
58333887	58333910	18	-	27869803	HPAFII	viability after 31 days	AAATTAGCATGGGTTACCGGTGG	NEDD4L	ENSG00000049759	-1.5059273463511458	[187]	[6,69,NaN]	-7	hSpCas9	negative selection	10059518
58333828	58333851	18	-	28162770	P31FUJ	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	-0.21753544776106815	[375]	[379]	-2	hSpCas9	negative selection	10199169
58341787	58341810	18	-	28162770	P31FUJ	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	0.09347791501269076	[330]	[414]	0	hSpCas9	negative selection	10199170
58325123	58325146	18	+	28162770	P31FUJ	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.1767182898968993	[130]	[173]	1	hSpCas9	negative selection	10199171
58330811	58330834	18	-	28162770	P31FUJ	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-0.7231278309974596	[176]	[125]	-5	hSpCas9	negative selection	10199172
58389165	58389188	18	-	28162770	P31FUJ	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	-0.984874690970793	[31]	[18]	-6	hSpCas9	negative selection	10199173
58329101	58329124	18	-	28162770	P31FUJ	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	1.089125890472984	[25]	[64]	9	hSpCas9	negative selection	10199174
58330801	58330824	18	-	28162770	P31FUJ	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	0.5011229354317766	[94]	[157]	5	hSpCas9	negative selection	10199175
58330833	58330856	18	-	28162770	P31FUJ	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.07101528768624021	[993]	[1226]	0	hSpCas9	negative selection	10199176
58341727	58341750	18	+	28162770	P31FUJ	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.13377890888214572	[438]	[565]	1	hSpCas9	negative selection	10199177
58341768	58341791	18	-	28162770	P31FUJ	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	1.9371227970279339	[9]	[44]	9	hSpCas9	negative selection	10199178
58333828	58333851	18	-	28162770	TF1	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	NaN	[NaN]	[327]	1	hSpCas9	negative selection	10368535
58341787	58341810	18	-	28162770	TF1	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	NaN	[NaN]	[442]	1	hSpCas9	negative selection	10368536
58325123	58325146	18	+	28162770	TF1	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	NaN	[NaN]	[148]	1	hSpCas9	negative selection	10368537
58330811	58330834	18	-	28162770	TF1	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10368538
58389165	58389188	18	-	28162770	TF1	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10368539
58329101	58329124	18	-	28162770	TF1	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10368540
58330801	58330824	18	-	28162770	TF1	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10368541
58330833	58330856	18	-	28162770	TF1	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	NaN	[NaN]	[786]	1	hSpCas9	negative selection	10368542
58341727	58341750	18	+	28162770	TF1	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	NaN	[NaN]	[472]	1	hSpCas9	negative selection	10368543
58341768	58341791	18	-	28162770	TF1	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10368544
58333828	58333851	18	-	28162770	SKM1	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	-0.523239587713686	[112]	[138]	-4	hSpCas9	negative selection	10537901
58341787	58341810	18	-	28162770	SKM1	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	0.1779983019779945	[69]	[139]	1	hSpCas9	negative selection	10537902
58325123	58325146	18	+	28162770	SKM1	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.4999263968653569	[43]	[109]	5	hSpCas9	negative selection	10537903
58330811	58330834	18	-	28162770	SKM1	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-0.3019946391416193	[52]	[75]	-3	hSpCas9	negative selection	10537904
58389165	58389188	18	-	28162770	SKM1	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	-0.7516123701306074	[19]	[20]	-5	hSpCas9	negative selection	10537905
58329101	58329124	18	-	28162770	SKM1	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	-2.6964708159381465	[10]	[2]	-9	hSpCas9	negative selection	10537906
58330801	58330824	18	-	28162770	SKM1	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	-0.9919266994643179	[17]	[15]	-6	hSpCas9	negative selection	10537907
58330833	58330856	18	-	28162770	SKM1	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	-0.24929666305613374	[196]	[292]	-2	hSpCas9	negative selection	10537908
58341727	58341750	18	+	28162770	SKM1	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.3901515388096042	[100]	[233]	4	hSpCas9	negative selection	10537909
58341768	58341791	18	-	28162770	SKM1	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	-1.4069641987431614	[5]	[3]	-7	hSpCas9	negative selection	10537910
58333828	58333851	18	-	28162770	SKM1	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	-0.523239587713686	[112]	[138]	-4	hSpCas9	negative selection	10707267
58341787	58341810	18	-	28162770	SKM1	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	0.1779983019779945	[69]	[139]	1	hSpCas9	negative selection	10707268
58325123	58325146	18	+	28162770	SKM1	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.4999263968653569	[43]	[109]	5	hSpCas9	negative selection	10707269
58330811	58330834	18	-	28162770	SKM1	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-0.3019946391416193	[52]	[75]	-3	hSpCas9	negative selection	10707270
58389165	58389188	18	-	28162770	SKM1	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	-0.7516123701306074	[19]	[20]	-5	hSpCas9	negative selection	10707271
58329101	58329124	18	-	28162770	SKM1	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	-2.6964708159381465	[10]	[2]	-9	hSpCas9	negative selection	10707272
58330801	58330824	18	-	28162770	SKM1	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	-0.9919266994643179	[17]	[15]	-6	hSpCas9	negative selection	10707273
58330833	58330856	18	-	28162770	SKM1	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	-0.24929666305613374	[196]	[292]	-2	hSpCas9	negative selection	10707274
58341727	58341750	18	+	28162770	SKM1	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.3901515388096042	[100]	[233]	4	hSpCas9	negative selection	10707275
58341768	58341791	18	-	28162770	SKM1	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	-1.4069641987431614	[5]	[3]	-7	hSpCas9	negative selection	10707276
58333828	58333851	18	-	28162770	PL21	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	-0.5966974356542847	[409]	[117]	-4	hSpCas9	negative selection	10876633
58341787	58341810	18	-	28162770	PL21	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	-0.3495474114843055	[201]	[68]	-3	hSpCas9	negative selection	10876634
58325123	58325146	18	+	28162770	PL21	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.5764447192794495	[150]	[97]	5	hSpCas9	negative selection	10876635
58330811	58330834	18	-	28162770	PL21	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-1.5871310615249514	[213]	[30]	-7	hSpCas9	negative selection	10876636
58389165	58389188	18	-	28162770	PL21	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	-3.3848228862318366	[47]	[1]	-9	hSpCas9	negative selection	10876637
58329101	58329124	18	-	28162770	PL21	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	1.2767608960922325	[54]	[57]	9	hSpCas9	negative selection	10876638
58330801	58330824	18	-	28162770	PL21	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	-0.2404329768966611	[37]	[13]	-2	hSpCas9	negative selection	10876639
58330833	58330856	18	-	28162770	PL21	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.3122903489024389	[667]	[360]	2	hSpCas9	negative selection	10876640
58341727	58341750	18	+	28162770	PL21	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.5970297670579047	[359]	[236]	5	hSpCas9	negative selection	10876641
58341768	58341791	18	-	28162770	PL21	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	-0.8873232267610196	[16]	[3]	-6	hSpCas9	negative selection	10876642
58333828	58333851	18	-	28162770	P31FUJ	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	-0.21753544776106815	[375]	[379]	-2	hSpCas9	negative selection	11045999
58341787	58341810	18	-	28162770	P31FUJ	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	0.09347791501269076	[330]	[414]	0	hSpCas9	negative selection	11046000
58325123	58325146	18	+	28162770	P31FUJ	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.1767182898968993	[130]	[173]	1	hSpCas9	negative selection	11046001
58330811	58330834	18	-	28162770	P31FUJ	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-0.7231278309974596	[176]	[125]	-5	hSpCas9	negative selection	11046002
58389165	58389188	18	-	28162770	P31FUJ	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	-0.984874690970793	[31]	[18]	-6	hSpCas9	negative selection	11046003
58329101	58329124	18	-	28162770	P31FUJ	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	1.089125890472984	[25]	[64]	9	hSpCas9	negative selection	11046004
58330801	58330824	18	-	28162770	P31FUJ	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	0.5011229354317766	[94]	[157]	5	hSpCas9	negative selection	11046005
58330833	58330856	18	-	28162770	P31FUJ	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.07101528768624021	[993]	[1226]	0	hSpCas9	negative selection	11046006
58341727	58341750	18	+	28162770	P31FUJ	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.13377890888214572	[438]	[565]	1	hSpCas9	negative selection	11046007
58341768	58341791	18	-	28162770	P31FUJ	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	1.9371227970279339	[9]	[44]	9	hSpCas9	negative selection	11046008
58333828	58333851	18	-	28162770	OCIAML5	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	-0.8866652323879637	[210]	[205]	-5	hSpCas9	negative selection	11215365
58341787	58341810	18	-	28162770	OCIAML5	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	0.30908822095058336	[109]	[245]	2	hSpCas9	negative selection	11215366
58325123	58325146	18	+	28162770	OCIAML5	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.526445052389733	[89]	[233]	4	hSpCas9	negative selection	11215367
58330811	58330834	18	-	28162770	OCIAML5	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-1.3532607138925554	[91]	[64]	-7	hSpCas9	negative selection	11215368
58389165	58389188	18	-	28162770	OCIAML5	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	0.7328959298571593	[9]	[29]	6	hSpCas9	negative selection	11215369
58329101	58329124	18	-	28162770	OCIAML5	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.3522919276421894	[22]	[52]	3	hSpCas9	negative selection	11215370
58330801	58330824	18	-	28162770	OCIAML5	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	0.2783300663916779	[36]	[80]	2	hSpCas9	negative selection	11215371
58330833	58330856	18	-	28162770	OCIAML5	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.4275985095139174	[574]	[1395]	3	hSpCas9	negative selection	11215372
58341727	58341750	18	+	28162770	OCIAML5	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.2654567326184958	[270]	[587]	2	hSpCas9	negative selection	11215373
58341768	58341791	18	-	28162770	OCIAML5	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	-0.19998987428430404	[20]	[32]	-1	hSpCas9	negative selection	11215374
58333828	58333851	18	-	28162770	EOL1	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	0.12169424174787136	[559]	[320]	1	hSpCas9	negative selection	11384731
58341787	58341810	18	-	28162770	EOL1	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	0.4093736010062409	[342]	[239]	4	hSpCas9	negative selection	11384732
58325123	58325146	18	+	28162770	EOL1	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	-0.08642334625046863	[263]	[130]	0	hSpCas9	negative selection	11384733
58330811	58330834	18	-	28162770	EOL1	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-0.10402138062623645	[356]	[174]	-1	hSpCas9	negative selection	11384734
58389165	58389188	18	-	28162770	EOL1	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	0.4143530392513508	[46]	[32]	4	hSpCas9	negative selection	11384735
58329101	58329124	18	-	28162770	EOL1	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	-0.9234491349844158	[71]	[19]	-6	hSpCas9	negative selection	11384736
58330801	58330824	18	-	28162770	EOL1	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	-1.6842614711049897	[121]	[19]	-8	hSpCas9	negative selection	11384737
58330833	58330856	18	-	28162770	EOL1	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.9399120812227142	[933]	[943]	7	hSpCas9	negative selection	11384738
58341727	58341750	18	+	28162770	EOL1	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.3061991023548317	[458]	[298]	2	hSpCas9	negative selection	11384739
58341768	58341791	18	-	28162770	EOL1	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	-2.075452228429466	[15]	[1]	-8	hSpCas9	negative selection	11384740
58333828	58333851	18	-	28162770	MOLM13	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	0.09646566872208784	[466]	[360]	0	hSpCas9	negative selection	11554097
58341787	58341810	18	-	28162770	MOLM13	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	0.09845584943915701	[300]	[232]	0	hSpCas9	negative selection	11554098
58325123	58325146	18	+	28162770	MOLM13	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.36583811007488154	[204]	[190]	2	hSpCas9	negative selection	11554099
58330811	58330834	18	-	28162770	MOLM13	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	0.062035204431070495	[260]	[196]	0	hSpCas9	negative selection	11554100
58389165	58389188	18	-	28162770	MOLM13	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	0.40648883688043536	[71]	[68]	3	hSpCas9	negative selection	11554101
58329101	58329124	18	-	28162770	MOLM13	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.14596128665721642	[24]	[19]	1	hSpCas9	negative selection	11554102
58330801	58330824	18	-	28162770	MOLM13	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	0.11500835832830436	[105]	[82]	0	hSpCas9	negative selection	11554103
58330833	58330856	18	-	28162770	MOLM13	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.1719289709837537	[1169]	[952]	1	hSpCas9	negative selection	11554104
58341727	58341750	18	+	28162770	MOLM13	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.7912772068495019	[595]	[248]	-4	hSpCas9	negative selection	11554105
58341768	58341791	18	-	28162770	MOLM13	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	1.271197470539481	[50]	[88]	8	hSpCas9	negative selection	11554106
58333828	58333851	18	-	28162770	HEL	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	0.5705890462445217	[450]	[428]	5	hSpCas9	negative selection	11723463
58341787	58341810	18	-	28162770	HEL	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	0.5009061375873975	[266]	[241]	4	hSpCas9	negative selection	11723464
58325123	58325146	18	+	28162770	HEL	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.2241347177013207	[269]	[201]	1	hSpCas9	negative selection	11723465
58330811	58330834	18	-	28162770	HEL	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-1.1898044221480804	[259]	[72]	-6	hSpCas9	negative selection	11723466
58389165	58389188	18	-	28162770	HEL	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	1.495181643586499	[35]	[64]	9	hSpCas9	negative selection	11723467
58329101	58329124	18	-	28162770	HEL	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	1.4203464106639092	[41]	[71]	9	hSpCas9	negative selection	11723468
58330801	58330824	18	-	28162770	HEL	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	1.2193860645095094	[115]	[172]	9	hSpCas9	negative selection	11723469
58330833	58330856	18	-	28162770	HEL	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.010706075257326253	[918]	[592]	0	hSpCas9	negative selection	11723470
58341727	58341750	18	+	28162770	HEL	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.7176124513170025	[412]	[434]	6	hSpCas9	negative selection	11723471
58341768	58341791	18	-	28162770	HEL	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	2.3797044261665627	[17]	[59]	9	hSpCas9	negative selection	11723472
58333828	58333851	18	-	28162770	MV411	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	-0.3653234022819529	[392]	[256]	-3	hSpCas9	negative selection	11892829
58341787	58341810	18	-	28162770	MV411	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	-0.47692800660379714	[227]	[137]	-4	hSpCas9	negative selection	11892830
58325123	58325146	18	+	28162770	MV411	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.638078395754152	[163]	[214]	6	hSpCas9	negative selection	11892831
58330811	58330834	18	-	28162770	MV411	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-1.767209225181626	[197]	[48]	-8	hSpCas9	negative selection	11892832
58389165	58389188	18	-	28162770	MV411	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	0.7899647851835347	[45]	[66]	7	hSpCas9	negative selection	11892833
58329101	58329124	18	-	28162770	MV411	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	-1.0326703684099598	[33]	[13]	-6	hSpCas9	negative selection	11892834
58330801	58330824	18	-	28162770	MV411	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	0.48190280441979816	[84]	[99]	4	hSpCas9	negative selection	11892835
58330833	58330856	18	-	28162770	MV411	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.26091178519946556	[745]	[752]	2	hSpCas9	negative selection	11892836
58341727	58341750	18	+	28162770	MV411	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.31265028129935146	[344]	[233]	-2	hSpCas9	negative selection	11892837
58341768	58341791	18	-	28162770	MV411	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	-0.4046391457969176	[21]	[13]	-3	hSpCas9	negative selection	11892838
58333828	58333851	18	-	28162770	MONOMAC1	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	-0.5491971433663312	[216]	[169]	-5	hSpCas9	negative selection	12062195
58341787	58341810	18	-	28162770	MONOMAC1	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	1.2144602945140415	[152]	[406]	9	hSpCas9	negative selection	12062196
58325123	58325146	18	+	28162770	MONOMAC1	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.10499169039010381	[72]	[89]	1	hSpCas9	negative selection	12062197
58330811	58330834	18	-	28162770	MONOMAC1	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-1.1011768316520374	[130]	[69]	-7	hSpCas9	negative selection	12062198
58389165	58389188	18	-	28162770	MONOMAC1	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	0.4056276553950613	[26]	[40]	4	hSpCas9	negative selection	12062199
58329101	58329124	18	-	28162770	MONOMAC1	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	0.49484085757811425	[25]	[41]	5	hSpCas9	negative selection	12062200
58330801	58330824	18	-	28162770	MONOMAC1	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	-0.12832409697553926	[40]	[42]	-1	hSpCas9	negative selection	12062201
58330833	58330856	18	-	28162770	MONOMAC1	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	-0.05389373053473201	[440]	[486]	0	hSpCas9	negative selection	12062202
58341727	58341750	18	+	28162770	MONOMAC1	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.2821534606975046	[191]	[180]	-2	hSpCas9	negative selection	12062203
58341768	58341791	18	-	28162770	MONOMAC1	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	1.4968600252147664	[16]	[54]	9	hSpCas9	negative selection	12062204
58333828	58333851	18	-	28162770	OCIAML2	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	0.08478839986497966	[73]	[434]	0	hSpCas9	negative selection	12231561
58341787	58341810	18	-	28162770	OCIAML2	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	-0.26753795986464973	[42]	[197]	-2	hSpCas9	negative selection	12231562
58325123	58325146	18	+	28162770	OCIAML2	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	0.7131673507817087	[22]	[208]	7	hSpCas9	negative selection	12231563
58330811	58330834	18	-	28162770	OCIAML2	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	-0.6326865833511339	[39]	[142]	-5	hSpCas9	negative selection	12231564
58389165	58389188	18	-	28162770	OCIAML2	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	0.007417471562483069	[6]	[38]	0	hSpCas9	negative selection	12231565
58329101	58329124	18	-	28162770	OCIAML2	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	-2.001144541940941	[12]	[17]	-8	hSpCas9	negative selection	12231566
58330801	58330824	18	-	28162770	OCIAML2	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	0.38735116988541085	[11]	[86]	4	hSpCas9	negative selection	12231567
58330833	58330856	18	-	28162770	OCIAML2	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	-0.17240599094606757	[134]	[663]	-1	hSpCas9	negative selection	12231568
58341727	58341750	18	+	28162770	OCIAML2	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	-0.4012084242846814	[70]	[297]	-3	hSpCas9	negative selection	12231569
58341768	58341791	18	-	28162770	OCIAML2	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	0.33672509681544316	[2]	[20]	3	hSpCas9	negative selection	12231570
58333828	58333851	18	-	28162770	OCIAML3	viability	GCATGACCTCAACCTTGAGGAGG	NEDD4L	ENSG00000049759	1.3962113388832513	[110]	[881]	9	hSpCas9	negative selection	12400927
58341787	58341810	18	-	28162770	OCIAML3	viability	TAGCCGTCTCACCTCCAGCGGGG	NEDD4L	ENSG00000049759	-0.2673571351943976	[60]	[152]	-2	hSpCas9	negative selection	12400928
58325123	58325146	18	+	28162770	OCIAML3	viability	ACAACAACCGGACCACTCAGTGG	NEDD4L	ENSG00000049759	-0.9033356984318921	[56]	[91]	-6	hSpCas9	negative selection	12400929
58330811	58330834	18	-	28162770	OCIAML3	viability	GCTGGTCCGAGATCCTGGGGAGG	NEDD4L	ENSG00000049759	0.6248269615990957	[57]	[269]	6	hSpCas9	negative selection	12400930
58389165	58389188	18	-	28162770	OCIAML3	viability	AGAACCACTGAATGACGGGGTGG	NEDD4L	ENSG00000049759	-1.079434467494405	[13]	[19]	-6	hSpCas9	negative selection	12400931
58329101	58329124	18	-	28162770	OCIAML3	viability	GGGACATCCCCGCCCTCCGAGGG	NEDD4L	ENSG00000049759	-4.763932641766475	[8]	[0]	-9	hSpCas9	negative selection	12400932
58330801	58330824	18	-	28162770	OCIAML3	viability	GATCCTGGGGAGGCCGGTGGTGG	NEDD4L	ENSG00000049759	-1.198078963993024	[18]	[24]	-7	hSpCas9	negative selection	12400933
58330833	58330856	18	-	28162770	OCIAML3	viability	GTTCCTCTGACAGCTCCTGAGGG	NEDD4L	ENSG00000049759	0.1429579538420429	[209]	[699]	1	hSpCas9	negative selection	12400934
58341727	58341750	18	+	28162770	OCIAML3	viability	TAATCGAGCCTCAGATCCGCCGG	NEDD4L	ENSG00000049759	0.39273626297357	[81]	[324]	3	hSpCas9	negative selection	12400935
58341768	58341791	18	-	28162770	OCIAML3	viability	GGGGCAGATAAAGTTACTGTTGG	NEDD4L	ENSG00000049759	-1.1789701410453195	[5]	[7]	-7	hSpCas9	negative selection	12400936