| 24216212 | 24216235 | 14 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | AGAAGTAGGGAGGATGCCCGTGG | NEDD8-MDP1 | ENSG00000255526 | 1.2962799348609915 | [38,33] | [33,3] | 5 | dCas9-VP64 | positive selection | 2410714 | 24216160 | 24216183 | 14 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGTTGCATGTGTGGTCGTGTTGG | NEDD8-MDP1 | ENSG00000255526 | 2.5411289501657524 | [545,193] | [859,51] | 8 | dCas9-VP64 | positive selection | 2410715 | 24216181 | 24216204 | 14 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TTAGAAAGACTTGACTGCTGTGG | NEDD8-MDP1 | ENSG00000255526 | 1.043527614428822 | [253,57] | [91,45] | 4 | dCas9-VP64 | positive selection | 2410716 | 24213993 | 24214016 | 14 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GAAATCAAGAAGGCATTTTCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.8686535570300185 | [44,84] | [4,9] | -5 | dCas9-VP64 | positive selection | 2443571 | 24216212 | 24216235 | 14 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | AGAAGTAGGGAGGATGCCCGTGG | NEDD8-MDP1 | ENSG00000255526 | -0.04610139876677721 | [137,206] | [39,66] | 0 | dCas9-VP64 | positive selection | 2505969 | 24216160 | 24216183 | 14 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGTTGCATGTGTGGTCGTGTTGG | NEDD8-MDP1 | ENSG00000255526 | 0.12027638088297038 | [85,229] | [53,56] | 1 | dCas9-VP64 | positive selection | 2505970 | 24216181 | 24216204 | 14 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TTAGAAAGACTTGACTGCTGTGG | NEDD8-MDP1 | ENSG00000255526 | -0.4331633734269753 | [471,172] | [90,65] | -4 | dCas9-VP64 | positive selection | 2505971 | 24213993 | 24214016 | 14 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GAAATCAAGAAGGCATTTTCAGG | NEDD8-MDP1 | ENSG00000255526 | 0.910755757889036 | [48,20] | [21,19] | 6 | dCas9-VP64 | positive selection | 2538826 | 24214516 | 24214539 | 14 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -1.3937254797330938 | [401,401] | [0,0] | -8 | hSpCas9 | positive selection | 3381410 | 24214557 | 24214580 | 14 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | 3.00939869800225 | [18,18] | [0,0] | 8 | hSpCas9 | positive selection | 3381411 | 24214557 | 24214580 | 14 | + | 26780180 | A375 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | 0.376206673861156 | [] | [] | 0 | hSpCas9 | negative selection | 3971775 | 24214516 | 24214539 | 14 | - | 26780180 | A375 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | 0.933722056610814 | [] | [] | 4 | hSpCas9 | negative selection | 3971776 | 24214557 | 24214580 | 14 | + | 26780180 | HT29 | viability (GeCKOv2 library) | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | 0.756700303508633 | [] | [] | 3 | hSpCas9 | negative selection | 4079741 | 24214516 | 24214539 | 14 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | 1.69058944421739 | [] | [] | 8 | hSpCas9 | negative selection | 4079742 | 24215761 | 24215784 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.049766240713501386 | [2] | [1,1] | -1 | hSpCas9 | positive selection | 4151225 | 24215610 | 24215633 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.2184811666982353 | [4] | [2,4] | 5 | hSpCas9 | positive selection | 4151226 | 24215576 | 24215599 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CTAAAACGATTGCAGAGCCTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.09919440024679632 | [2] | [0,1] | -2 | hSpCas9 | positive selection | 4151227 | 24215784 | 24215807 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.05867145678485863 | [4] | [3,2] | 1 | hSpCas9 | positive selection | 4151228 | 24215761 | 24215784 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.13001437241249653 | [2] | [0,2,1,0] | 1 | hSpCas9 | positive selection | 4215247 | 24215610 | 24215633 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.937193005146504 | [4] | [2,2,3,4] | 6 | hSpCas9 | positive selection | 4215248 | 24215576 | 24215599 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CTAAAACGATTGCAGAGCCTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.21877704278897392 | [3] | [1,2,0,0] | -3 | hSpCas9 | positive selection | 4215249 | 24215784 | 24215807 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.17835982630406833 | [4] | [4,0,5,0] | 1 | hSpCas9 | positive selection | 4215250 | 24215641 | 24215664 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.014894506925127893 | [3] | [2,2] | 0 | hSpCas9 | positive selection | 4282365 | 24215761 | 24215784 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.18717810307499638 | [2] | [3,1] | 4 | hSpCas9 | positive selection | 4282366 | 24215784 | 24215807 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.840942677830193 | [2] | [1,0] | -9 | hSpCas9 | positive selection | 4282367 | 24215641 | 24215664 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.014894506925127893 | [3] | [2,2] | 0 | hSpCas9 | positive selection | 4285267 | 24215610 | 24215633 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.2678707281039305 | [2] | [2,1] | 5 | hSpCas9 | positive selection | 4346623 | 24214553 | 24214576 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.31065089285021735 | [2] | [2,0] | -6 | hSpCas9 | positive selection | 4346624 | 24214582 | 24214605 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.2805858027910037 | [3] | [3,2] | 5 | hSpCas9 | positive selection | 4346625 | 24215610 | 24215633 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.2678707281039305 | [2] | [2,1] | 5 | hSpCas9 | positive selection | 4349525 | 24214516 | 24214539 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | 0.059845663302463825 | [4] | [4,2] | 1 | hSpCas9 | positive selection | 4349526 | 24214557 | 24214580 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.21874293746420848 | [0] | [0,0] | -4 | hSpCas9 | positive selection | 4349527 | 24215969 | 24215992 | 14 | + | 27661255 | K562 | viability | GGCTGCGCGCAGCAGAGGTGGGG | NEDD8-MDP1 | ENSG00000255526 | 0.05178579155480917 | [855,819] | [776,623] | 1 | dCas9-KRAB | negative selection | 5470786 | 24215562 | 24215585 | 14 | - | 27661255 | K562 | viability | GAGCCTTGGGGTGCCCGGTGCGG | NEDD8-MDP1 | ENSG00000255526 | -0.02931175204064551 | [1098,985] | [829,806] | -1 | dCas9-KRAB | negative selection | 5470787 | 24215919 | 24215942 | 14 | - | 27661255 | K562 | viability | GAAGCTGGCAGTCTTTGATTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.01598538804033167 | [863,1015] | [808,681] | 0 | dCas9-KRAB | negative selection | 5470788 | 24215952 | 24215975 | 14 | - | 27661255 | K562 | viability | GCAGCCTGCGGTGCGGGTCATGG | NEDD8-MDP1 | ENSG00000255526 | -0.0002804592877261036 | [695,609] | [586,467] | 0 | dCas9-KRAB | negative selection | 5470789 | 24215969 | 24215992 | 14 | + | 27661255 | K562 | viability | GGCTGCGCGCAGCAGAGGTGGGG | NEDD8-MDP1 | ENSG00000255526 | 0.05178579155480917 | [855,819] | [776,623] | 1 | dCas9-KRAB | negative selection | 5492737 | 24215562 | 24215585 | 14 | - | 27661255 | K562 | viability | GAGCCTTGGGGTGCCCGGTGCGG | NEDD8-MDP1 | ENSG00000255526 | -0.02931175204064551 | [1098,985] | [829,806] | -1 | dCas9-KRAB | negative selection | 5492738 | 24215641 | 24215664 | 14 | - | 27661255 | K562 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.14919522337327507 | [1341,1128] | [1160,1043] | 5 | dCas9-KRAB | negative selection | 5492739 | 24216021 | 24216044 | 14 | - | 27661255 | K562 | viability | GTGGCTGCCTTAGCTGCCGGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.01627567844710931 | [928,886] | [720,714] | 0 | dCas9-KRAB | negative selection | 5492740 | 24215641 | 24215664 | 14 | - | 27260156 | BXPC3 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.01563077398879331 | [763] | [718,682,797,994] | 0 | hSpCas9 | negative selection | 5554825 | 24215761 | 24215784 | 14 | + | 27260156 | BXPC3 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.2496461366185106 | [418] | [560,462,500,557] | 5 | hSpCas9 | negative selection | 5554826 | 24215784 | 24215807 | 14 | - | 27260156 | BXPC3 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.0306555003226629 | [417] | [428,342,472,474] | 0 | hSpCas9 | negative selection | 5554827 | 24215641 | 24215664 | 14 | - | 27260156 | BXPC3 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.01563077398879331 | [763] | [718,682,797,994] | 0 | hSpCas9 | negative selection | 5557727 | 24215610 | 24215633 | 14 | - | 27260156 | BXPC3 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.1493804856702109 | [226] | [272,186,264,338] | 3 | hSpCas9 | negative selection | 5619083 | 24214553 | 24214576 | 14 | + | 27260156 | BXPC3 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.2787377260837925 | [435] | [410,343,336,409] | -6 | hSpCas9 | negative selection | 5619084 | 24214582 | 24214605 | 14 | - | 27260156 | BXPC3 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.22017534279027118 | [581] | [486,485,533,593] | -5 | hSpCas9 | negative selection | 5619085 | 24215610 | 24215633 | 14 | - | 27260156 | BXPC3 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.1493804856702109 | [226] | [272,186,264,338] | 3 | hSpCas9 | negative selection | 5621985 | 24214516 | 24214539 | 14 | - | 27260156 | BXPC3 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | 0.13337575245259248 | [1355] | [1090,1656,1607,1947] | 3 | hSpCas9 | negative selection | 5621986 | 24214557 | 24214580 | 14 | + | 27260156 | BXPC3 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.7409916667028256 | [39] | [8,24,42,24] | -9 | hSpCas9 | negative selection | 5621987 | 24215641 | 24215664 | 14 | - | 27260156 | A673 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.06886259471944489 | [763] | [1111,961,834,955] | 1 | hSpCas9 | negative selection | 5676076 | 24215761 | 24215784 | 14 | + | 27260156 | A673 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.03697849620585189 | [418] | [518,485,528,425] | -1 | hSpCas9 | negative selection | 5676077 | 24215784 | 24215807 | 14 | - | 27260156 | A673 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.05467754812654392 | [417] | [472,423,512,679] | 1 | hSpCas9 | negative selection | 5676078 | 24215641 | 24215664 | 14 | - | 27260156 | A673 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.06886259471944489 | [763] | [1111,961,834,955] | 1 | hSpCas9 | negative selection | 5678978 | 24215610 | 24215633 | 14 | - | 27260156 | A673 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.05479616278661936 | [226] | [266,212,227,347] | -1 | hSpCas9 | negative selection | 5740334 | 24214553 | 24214576 | 14 | + | 27260156 | A673 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.42816709053566027 | [435] | [420,493,336,299] | -8 | hSpCas9 | negative selection | 5740335 | 24214582 | 24214605 | 14 | - | 27260156 | A673 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.24381504443487642 | [581] | [718,551,558,542] | -6 | hSpCas9 | negative selection | 5740336 | 24215610 | 24215633 | 14 | - | 27260156 | A673 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.05479616278661936 | [226] | [266,212,227,347] | -1 | hSpCas9 | negative selection | 5743236 | 24214516 | 24214539 | 14 | - | 27260156 | A673 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2474056594327001 | [1355] | [1506,1367,1347,1270] | -6 | hSpCas9 | negative selection | 5743237 | 24214557 | 24214580 | 14 | + | 27260156 | A673 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.9632035215079275 | [39] | [17,11,26,41] | -9 | hSpCas9 | negative selection | 5743238 | 24215641 | 24215664 | 14 | - | 27260156 | A375 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.45571399378560845 | [763] | [635,876,546,579] | -6 | hSpCas9 | negative selection | 5797327 | 24215761 | 24215784 | 14 | + | 27260156 | A375 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.053981653359524526 | [418] | [633,526,560,332] | 0 | hSpCas9 | negative selection | 5797328 | 24215784 | 24215807 | 14 | - | 27260156 | A375 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.47742098259425786 | [417] | [633,738,706,647] | 7 | hSpCas9 | negative selection | 5797329 | 24215641 | 24215664 | 14 | - | 27260156 | A375 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.45571399378560845 | [763] | [635,876,546,579] | -6 | hSpCas9 | negative selection | 5800229 | 24215610 | 24215633 | 14 | - | 27260156 | A375 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.058485275227338596 | [226] | [191,454,235,247] | 0 | hSpCas9 | negative selection | 5861585 | 24214553 | 24214576 | 14 | + | 27260156 | A375 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.0978666084066981 | [435] | [470,755,585,409] | 1 | hSpCas9 | negative selection | 5861586 | 24214582 | 24214605 | 14 | - | 27260156 | A375 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.38056132547135574 | [581] | [647,601,403,452] | -5 | hSpCas9 | negative selection | 5861587 | 24215610 | 24215633 | 14 | - | 27260156 | A375 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.058485275227338596 | [226] | [191,454,235,247] | 0 | hSpCas9 | negative selection | 5864487 | 24214516 | 24214539 | 14 | - | 27260156 | A375 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.11943507374120488 | [1355] | [1419,1696,1347,1400] | -2 | hSpCas9 | negative selection | 5864488 | 24214557 | 24214580 | 14 | + | 27260156 | A375 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.9716783666319522 | [39] | [0,21,49,21] | -8 | hSpCas9 | negative selection | 5864489 | 24215641 | 24215664 | 14 | - | 27260156 | COLO741 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.20491692842508702 | [763] | [1037,1108,1211] | 4 | hSpCas9 | negative selection | 5918578 | 24215761 | 24215784 | 14 | + | 27260156 | COLO741 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.1952636256516036 | [418] | [696,639,514] | 4 | hSpCas9 | negative selection | 5918579 | 24215784 | 24215807 | 14 | - | 27260156 | COLO741 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.2297506142375302 | [417] | [557,578,726] | 5 | hSpCas9 | negative selection | 5918580 | 24215641 | 24215664 | 14 | - | 27260156 | COLO741 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.20491692842508702 | [763] | [1037,1108,1211] | 4 | hSpCas9 | negative selection | 5921480 | 24215610 | 24215633 | 14 | - | 27260156 | COLO741 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.322853510116607 | [226] | [345,249,480] | 6 | hSpCas9 | negative selection | 5982836 | 24214553 | 24214576 | 14 | + | 27260156 | COLO741 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.3652345023602828 | [435] | [400,475,417] | -7 | hSpCas9 | negative selection | 5982837 | 24214582 | 24214605 | 14 | - | 27260156 | COLO741 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.4643052214018016 | [581] | [655,465,505] | -7 | hSpCas9 | negative selection | 5982838 | 24215610 | 24215633 | 14 | - | 27260156 | COLO741 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.322853510116607 | [226] | [345,249,480] | 6 | hSpCas9 | negative selection | 5985738 | 24214516 | 24214539 | 14 | - | 27260156 | COLO741 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | 0.15702701013862352 | [1355] | [1825,2507,1482] | 3 | hSpCas9 | negative selection | 5985739 | 24214557 | 24214580 | 14 | + | 27260156 | COLO741 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.08990143489526581 | [39] | [66,64,15] | -2 | hSpCas9 | negative selection | 5985740 | 24215641 | 24215664 | 14 | - | 27260156 | CAL120 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.1357960665609751 | [763] | [1051,669,900] | -2 | hSpCas9 | negative selection | 6039829 | 24215761 | 24215784 | 14 | + | 27260156 | CAL120 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.05475597011687541 | [418] | [428,409,652] | -1 | hSpCas9 | negative selection | 6039830 | 24215784 | 24215807 | 14 | - | 27260156 | CAL120 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.007552857078581804 | [417] | [585,416,573] | 0 | hSpCas9 | negative selection | 6039831 | 24215641 | 24215664 | 14 | - | 27260156 | CAL120 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.1357960665609751 | [763] | [1051,669,900] | -2 | hSpCas9 | negative selection | 6042731 | 24215610 | 24215633 | 14 | - | 27260156 | CAL120 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.17767129088960854 | [226] | [419,374,180] | 2 | hSpCas9 | negative selection | 6104087 | 24214553 | 24214576 | 14 | + | 27260156 | CAL120 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.11962498429682478 | [435] | [1209,313,341] | 1 | hSpCas9 | negative selection | 6104088 | 24214582 | 24214605 | 14 | - | 27260156 | CAL120 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.22260005324600735 | [581] | [357,1674,435] | 3 | hSpCas9 | negative selection | 6104089 | 24215610 | 24215633 | 14 | - | 27260156 | CAL120 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.17767129088960854 | [226] | [419,374,180] | 2 | hSpCas9 | negative selection | 6106989 | 24214516 | 24214539 | 14 | - | 27260156 | CAL120 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.24103394140605428 | [1355] | [1803,1257,1279] | -4 | hSpCas9 | negative selection | 6106990 | 24214557 | 24214580 | 14 | + | 27260156 | CAL120 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -1.00846431046718 | [39] | [25,0,46] | -8 | hSpCas9 | negative selection | 6106991 | 24215641 | 24215664 | 14 | - | 27260156 | CADOES1 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.07510375323724328 | [763] | [573,577,771,777] | -1 | hSpCas9 | negative selection | 6161080 | 24215761 | 24215784 | 14 | + | 27260156 | CADOES1 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.08612711346896974 | [418] | [422,388,392,450] | 1 | hSpCas9 | negative selection | 6161081 | 24215784 | 24215807 | 14 | - | 27260156 | CADOES1 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.4147146046543689 | [417] | [562,558,481,466] | 7 | hSpCas9 | negative selection | 6161082 | 24215641 | 24215664 | 14 | - | 27260156 | CADOES1 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.07510375323724328 | [763] | [573,577,771,777] | -1 | hSpCas9 | negative selection | 6163982 | 24215610 | 24215633 | 14 | - | 27260156 | CADOES1 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.3805069085215891 | [226] | [181,120,146,199] | -6 | hSpCas9 | negative selection | 6225338 | 24214553 | 24214576 | 14 | + | 27260156 | CADOES1 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.328094262778277 | [435] | [328,333,282,346] | -5 | hSpCas9 | negative selection | 6225339 | 24214582 | 24214605 | 14 | - | 27260156 | CADOES1 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.0022936155307152206 | [581] | [689,563,405,506] | 0 | hSpCas9 | negative selection | 6225340 | 24215610 | 24215633 | 14 | - | 27260156 | CADOES1 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.3805069085215891 | [226] | [181,120,146,199] | -6 | hSpCas9 | negative selection | 6228240 | 24214516 | 24214539 | 14 | - | 27260156 | CADOES1 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.22887838258202264 | [1355] | [950,1013,1281,1056] | -4 | hSpCas9 | negative selection | 6228241 | 24214557 | 24214580 | 14 | + | 27260156 | CADOES1 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.592329501378523 | [39] | [63,16,7,8] | -8 | hSpCas9 | negative selection | 6228242 | 24215641 | 24215664 | 14 | - | 27260156 | EWS502 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.020871470429401295 | [763] | [883,641,662,1109] | 0 | hSpCas9 | negative selection | 6282331 | 24215761 | 24215784 | 14 | + | 27260156 | EWS502 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.17031197253980493 | [418] | [457,607,482,442] | 3 | hSpCas9 | negative selection | 6282332 | 24215784 | 24215807 | 14 | - | 27260156 | EWS502 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.2538868232097124 | [417] | [384,467,647,637] | 4 | hSpCas9 | negative selection | 6282333 | 24215641 | 24215664 | 14 | - | 27260156 | EWS502 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.020871470429401295 | [763] | [883,641,662,1109] | 0 | hSpCas9 | negative selection | 6285233 | 24215610 | 24215633 | 14 | - | 27260156 | EWS502 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.08361799337916975 | [226] | [182,264,330,247] | 1 | hSpCas9 | negative selection | 6346589 | 24214553 | 24214576 | 14 | + | 27260156 | EWS502 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.12278150310160921 | [435] | [378,419,449,453] | -2 | hSpCas9 | negative selection | 6346590 | 24214582 | 24214605 | 14 | - | 27260156 | EWS502 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.26501853487291743 | [581] | [357,622,556,527] | -5 | hSpCas9 | negative selection | 6346591 | 24215610 | 24215633 | 14 | - | 27260156 | EWS502 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.08361799337916975 | [226] | [182,264,330,247] | 1 | hSpCas9 | negative selection | 6349491 | 24214516 | 24214539 | 14 | - | 27260156 | EWS502 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.11258125352793202 | [1355] | [1195,1123,1383,1652] | -2 | hSpCas9 | negative selection | 6349492 | 24214557 | 24214580 | 14 | + | 27260156 | EWS502 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.4105935454816594 | [39] | [48,25,23,25] | -6 | hSpCas9 | negative selection | 6349493 | 24215641 | 24215664 | 14 | - | 27260156 | EW8 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.020728891524910087 | [763] | [643,583,556,666] | 0 | hSpCas9 | negative selection | 6403582 | 24215761 | 24215784 | 14 | + | 27260156 | EW8 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.002739650077474648 | [418] | [382,383,260,344] | 0 | hSpCas9 | negative selection | 6403583 | 24215784 | 24215807 | 14 | - | 27260156 | EW8 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.1317744297697254 | [417] | [439,307,291,463] | 2 | hSpCas9 | negative selection | 6403584 | 24215641 | 24215664 | 14 | - | 27260156 | EW8 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.020728891524910087 | [763] | [643,583,556,666] | 0 | hSpCas9 | negative selection | 6406484 | 24215610 | 24215633 | 14 | - | 27260156 | EW8 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.4997058032054411 | [226] | [148,124,160,81] | -7 | hSpCas9 | negative selection | 6467840 | 24214553 | 24214576 | 14 | + | 27260156 | EW8 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.3931784881007808 | [435] | [382,381,167,172] | -6 | hSpCas9 | negative selection | 6467841 | 24214582 | 24214605 | 14 | - | 27260156 | EW8 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.14260511962768063 | [581] | [552,331,368,476] | -3 | hSpCas9 | negative selection | 6467842 | 24215610 | 24215633 | 14 | - | 27260156 | EW8 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.4997058032054411 | [226] | [148,124,160,81] | -7 | hSpCas9 | negative selection | 6470742 | 24214516 | 24214539 | 14 | - | 27260156 | EW8 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.04841142565602863 | [1355] | [1258,1216,755,1089] | -1 | hSpCas9 | negative selection | 6470743 | 24214557 | 24214580 | 14 | + | 27260156 | EW8 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.8445362043563112 | [39] | [1,36,14,16] | -9 | hSpCas9 | negative selection | 6470744 | 24215641 | 24215664 | 14 | - | 27260156 | CORL105 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.056111997412413794 | [763] | [947,724,1020,777] | -1 | hSpCas9 | negative selection | 6524833 | 24215761 | 24215784 | 14 | + | 27260156 | CORL105 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.1298890002505698 | [418] | [475,532,483,642] | 2 | hSpCas9 | negative selection | 6524834 | 24215784 | 24215807 | 14 | - | 27260156 | CORL105 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.09047680052648366 | [417] | [604,322,309,583] | -2 | hSpCas9 | negative selection | 6524835 | 24215641 | 24215664 | 14 | - | 27260156 | CORL105 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.056111997412413794 | [763] | [947,724,1020,777] | -1 | hSpCas9 | negative selection | 6527735 | 24215610 | 24215633 | 14 | - | 27260156 | CORL105 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.3867291001817976 | [226] | [243,125,279,177] | -6 | hSpCas9 | negative selection | 6589091 | 24214553 | 24214576 | 14 | + | 27260156 | CORL105 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.458402458997886 | [435] | [357,346,354,422] | -7 | hSpCas9 | negative selection | 6589092 | 24214582 | 24214605 | 14 | - | 27260156 | CORL105 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.4970684164248646 | [581] | [502,347,646,461] | -7 | hSpCas9 | negative selection | 6589093 | 24215610 | 24215633 | 14 | - | 27260156 | CORL105 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.3867291001817976 | [226] | [243,125,279,177] | -6 | hSpCas9 | negative selection | 6591993 | 24214516 | 24214539 | 14 | - | 27260156 | CORL105 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2397943508067093 | [1355] | [1202,1542,1497,1148] | -4 | hSpCas9 | negative selection | 6591994 | 24214557 | 24214580 | 14 | + | 27260156 | CORL105 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | 0.421420094584692 | [39] | [22,92,94,42] | 7 | hSpCas9 | negative selection | 6591995 | 24215641 | 24215664 | 14 | - | 27260156 | HS294T | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.20242182003980475 | [763] | [190,232,318,296] | -3 | hSpCas9 | negative selection | 6646084 | 24215761 | 24215784 | 14 | + | 27260156 | HS294T | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.20830565587613156 | [418] | [163,180,200,207] | 3 | hSpCas9 | negative selection | 6646085 | 24215784 | 24215807 | 14 | - | 27260156 | HS294T | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.30911789971194015 | [417] | [251,258,107,168] | 4 | hSpCas9 | negative selection | 6646086 | 24215641 | 24215664 | 14 | - | 27260156 | HS294T | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.20242182003980475 | [763] | [190,232,318,296] | -3 | hSpCas9 | negative selection | 6648986 | 24215610 | 24215633 | 14 | - | 27260156 | HS294T | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.3267815223034871 | [226] | [149,154,56,64] | 4 | hSpCas9 | negative selection | 6710342 | 24214553 | 24214576 | 14 | + | 27260156 | HS294T | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.29664250321062874 | [435] | [96,158,91,216] | -4 | hSpCas9 | negative selection | 6710343 | 24214582 | 24214605 | 14 | - | 27260156 | HS294T | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.07659025295998256 | [581] | [165,273,183,234] | -1 | hSpCas9 | negative selection | 6710344 | 24215610 | 24215633 | 14 | - | 27260156 | HS294T | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.3267815223034871 | [226] | [149,154,56,64] | 4 | hSpCas9 | negative selection | 6713244 | 24214516 | 24214539 | 14 | - | 27260156 | HS294T | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2744581173409846 | [1355] | [430,430,405,470] | -4 | hSpCas9 | negative selection | 6713245 | 24214557 | 24214580 | 14 | + | 27260156 | HS294T | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -1.8989497594102893 | [39] | [2,3,3,5] | -9 | hSpCas9 | negative selection | 6713246 | 24215641 | 24215664 | 14 | - | 27260156 | HCC44 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.8463077383927301 | [763] | [511,489,563,371] | -8 | hSpCas9 | negative selection | 6767335 | 24215761 | 24215784 | 14 | + | 27260156 | HCC44 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.13968073652807755 | [418] | [592,559,543,395] | 2 | hSpCas9 | negative selection | 6767336 | 24215784 | 24215807 | 14 | - | 27260156 | HCC44 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.1270909499054304 | [417] | [432,567,573,481] | 2 | hSpCas9 | negative selection | 6767337 | 24215641 | 24215664 | 14 | - | 27260156 | HCC44 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.8463077383927301 | [763] | [511,489,563,371] | -8 | hSpCas9 | negative selection | 6770237 | 24215610 | 24215633 | 14 | - | 27260156 | HCC44 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.49796464254266404 | [226] | [206,198,171,146] | -6 | hSpCas9 | negative selection | 6831593 | 24214553 | 24214576 | 14 | + | 27260156 | HCC44 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.6251375889326951 | [435] | [480,226,386,223] | -7 | hSpCas9 | negative selection | 6831594 | 24214582 | 24214605 | 14 | - | 27260156 | HCC44 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -1.0292211588313216 | [581] | [223,306,521,263] | -8 | hSpCas9 | negative selection | 6831595 | 24215610 | 24215633 | 14 | - | 27260156 | HCC44 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.49796464254266404 | [226] | [206,198,171,146] | -6 | hSpCas9 | negative selection | 6834495 | 24214516 | 24214539 | 14 | - | 27260156 | HCC44 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.526723725886344 | [1355] | [1107,1298,1013,798] | -7 | hSpCas9 | negative selection | 6834496 | 24214557 | 24214580 | 14 | + | 27260156 | HCC44 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.10594368206709825 | [39] | [10,89,11,39] | -2 | hSpCas9 | negative selection | 6834497 | 24215641 | 24215664 | 14 | - | 27260156 | G402 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.5377585427868771 | [763] | [678,482,583,807] | -6 | hSpCas9 | negative selection | 6888586 | 24215761 | 24215784 | 14 | + | 27260156 | G402 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.10802607831791741 | [418] | [394,351,695,435] | -1 | hSpCas9 | negative selection | 6888587 | 24215784 | 24215807 | 14 | - | 27260156 | G402 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.4517574585971699 | [417] | [1003,952,345,550] | 5 | hSpCas9 | negative selection | 6888588 | 24215641 | 24215664 | 14 | - | 27260156 | G402 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.5377585427868771 | [763] | [678,482,583,807] | -6 | hSpCas9 | negative selection | 6891488 | 24215610 | 24215633 | 14 | - | 27260156 | G402 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.34726806393378173 | [226] | [330,314,534,227] | 4 | hSpCas9 | negative selection | 6952844 | 24214553 | 24214576 | 14 | + | 27260156 | G402 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.32891457905268867 | [435] | [640,385,381,317] | -4 | hSpCas9 | negative selection | 6952845 | 24214582 | 24214605 | 14 | - | 27260156 | G402 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.11308309167668176 | [581] | [698,744,551,639] | -1 | hSpCas9 | negative selection | 6952846 | 24215610 | 24215633 | 14 | - | 27260156 | G402 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.34726806393378173 | [226] | [330,314,534,227] | 4 | hSpCas9 | negative selection | 6955746 | 24214516 | 24214539 | 14 | - | 27260156 | G402 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.20669536557111767 | [1355] | [1101,1443,1594,1535] | -3 | hSpCas9 | negative selection | 6955747 | 24214557 | 24214580 | 14 | + | 27260156 | G402 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -2.053696730324062 | [39] | [10,27,0,7] | -9 | hSpCas9 | negative selection | 6955748 | 24215641 | 24215664 | 14 | - | 27260156 | L33 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.16339399993989745 | [763] | [950,372,532,711] | 3 | hSpCas9 | negative selection | 7009837 | 24215761 | 24215784 | 14 | + | 27260156 | L33 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.4559262713960025 | [418] | [549,292,376,435] | 8 | hSpCas9 | negative selection | 7009838 | 24215784 | 24215807 | 14 | - | 27260156 | L33 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.0912232466783004 | [417] | [340,166,237,442] | -2 | hSpCas9 | negative selection | 7009839 | 24215641 | 24215664 | 14 | - | 27260156 | L33 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.16339399993989745 | [763] | [950,372,532,711] | 3 | hSpCas9 | negative selection | 7012739 | 24215610 | 24215633 | 14 | - | 27260156 | L33 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.1792705230110898 | [226] | [171,45,165,253] | -4 | hSpCas9 | negative selection | 7074095 | 24214553 | 24214576 | 14 | + | 27260156 | L33 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.5617044716895682 | [435] | [332,144,137,273] | -8 | hSpCas9 | negative selection | 7074096 | 24214582 | 24214605 | 14 | - | 27260156 | L33 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.030532927953726252 | [581] | [439,256,348,658] | 0 | hSpCas9 | negative selection | 7074097 | 24215610 | 24215633 | 14 | - | 27260156 | L33 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.1792705230110898 | [226] | [171,45,165,253] | -4 | hSpCas9 | negative selection | 7076997 | 24214516 | 24214539 | 14 | - | 27260156 | L33 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2042240048780064 | [1355] | [1287,373,865,1127] | -5 | hSpCas9 | negative selection | 7076998 | 24214557 | 24214580 | 14 | + | 27260156 | L33 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.7060363880022704 | [39] | [24,3,11,43] | -9 | hSpCas9 | negative selection | 7076999 | 24215641 | 24215664 | 14 | - | 27260156 | K562 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.4902463943235136 | [763] | [457,348,567,537] | -5 | hSpCas9 | negative selection | 7131088 | 24215761 | 24215784 | 14 | + | 27260156 | K562 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.12666327110779096 | [418] | [416,605,331,291] | 1 | hSpCas9 | negative selection | 7131089 | 24215784 | 24215807 | 14 | - | 27260156 | K562 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.3618217453808815 | [417] | [414,548,203,707] | 4 | hSpCas9 | negative selection | 7131090 | 24215641 | 24215664 | 14 | - | 27260156 | K562 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.4902463943235136 | [763] | [457,348,567,537] | -5 | hSpCas9 | negative selection | 7133990 | 24215610 | 24215633 | 14 | - | 27260156 | K562 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.3380547307600119 | [226] | [171,223,234,364] | 4 | hSpCas9 | negative selection | 7195346 | 24214553 | 24214576 | 14 | + | 27260156 | K562 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.07046832032853122 | [435] | [303,684,444,217] | 0 | hSpCas9 | negative selection | 7195347 | 24214582 | 24214605 | 14 | - | 27260156 | K562 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.5328240161495001 | [581] | [274,386,455,308] | -6 | hSpCas9 | negative selection | 7195348 | 24215610 | 24215633 | 14 | - | 27260156 | K562 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.3380547307600119 | [226] | [171,223,234,364] | 4 | hSpCas9 | negative selection | 7198248 | 24214516 | 24214539 | 14 | - | 27260156 | K562 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.1099437975342985 | [1355] | [1069,1377,1198,849] | -1 | hSpCas9 | negative selection | 7198249 | 24214557 | 24214580 | 14 | + | 27260156 | K562 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -2.6310346952053196 | [39] | [3,0,6,9] | -9 | hSpCas9 | negative selection | 7198250 | 24215641 | 24215664 | 14 | - | 27260156 | HT29 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.09794011572123407 | [763] | [1122,944,1079,844] | 1 | hSpCas9 | negative selection | 7252339 | 24215761 | 24215784 | 14 | + | 27260156 | HT29 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.07101977097466458 | [418] | [410,498,585,440] | -1 | hSpCas9 | negative selection | 7252340 | 24215784 | 24215807 | 14 | - | 27260156 | HT29 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.14263970636505363 | [417] | [439,507,446,446] | -3 | hSpCas9 | negative selection | 7252341 | 24215641 | 24215664 | 14 | - | 27260156 | HT29 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.09794011572123407 | [763] | [1122,944,1079,844] | 1 | hSpCas9 | negative selection | 7255241 | 24215610 | 24215633 | 14 | - | 27260156 | HT29 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.25592069392118977 | [226] | [321,209,210,189] | -5 | hSpCas9 | negative selection | 7316597 | 24214553 | 24214576 | 14 | + | 27260156 | HT29 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.3006671901892575 | [435] | [653,315,392,369] | -5 | hSpCas9 | negative selection | 7316598 | 24214582 | 24214605 | 14 | - | 27260156 | HT29 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.3411967420698318 | [581] | [521,786,507,443] | -6 | hSpCas9 | negative selection | 7316599 | 24215610 | 24215633 | 14 | - | 27260156 | HT29 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.25592069392118977 | [226] | [321,209,210,189] | -5 | hSpCas9 | negative selection | 7319499 | 24214516 | 24214539 | 14 | - | 27260156 | HT29 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.263725619436193 | [1355] | [1540,1365,1328,1270] | -5 | hSpCas9 | negative selection | 7319500 | 24214557 | 24214580 | 14 | + | 27260156 | HT29 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -1.9593372705585184 | [39] | [29,12,1,6] | -9 | hSpCas9 | negative selection | 7319501 | 24215641 | 24215664 | 14 | - | 27260156 | MHHES1 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.10112851479062224 | [763] | [776,1034,795,640] | -2 | hSpCas9 | negative selection | 7373590 | 24215761 | 24215784 | 14 | + | 27260156 | MHHES1 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.1483664644113998 | [418] | [283,356,758,300] | -3 | hSpCas9 | negative selection | 7373591 | 24215784 | 24215807 | 14 | - | 27260156 | MHHES1 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.27755802667511564 | [417] | [916,517,606,322] | 5 | hSpCas9 | negative selection | 7373592 | 24215641 | 24215664 | 14 | - | 27260156 | MHHES1 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.10112851479062224 | [763] | [776,1034,795,640] | -2 | hSpCas9 | negative selection | 7376492 | 24215610 | 24215633 | 14 | - | 27260156 | MHHES1 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.5995253012309498 | [226] | [139,205,200,132] | -8 | hSpCas9 | negative selection | 7437848 | 24214553 | 24214576 | 14 | + | 27260156 | MHHES1 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.3498751195672364 | [435] | [714,311,286,275] | -6 | hSpCas9 | negative selection | 7437849 | 24214582 | 24214605 | 14 | - | 27260156 | MHHES1 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.3177350382079994 | [581] | [866,379,537,369] | -5 | hSpCas9 | negative selection | 7437850 | 24215610 | 24215633 | 14 | - | 27260156 | MHHES1 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.5995253012309498 | [226] | [139,205,200,132] | -8 | hSpCas9 | negative selection | 7440750 | 24214516 | 24214539 | 14 | - | 27260156 | MHHES1 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.15895000880057175 | [1355] | [1587,1374,1501,1072] | -3 | hSpCas9 | negative selection | 7440751 | 24214557 | 24214580 | 14 | + | 27260156 | MHHES1 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -2.1138235129061913 | [39] | [18,7,3,10] | -9 | hSpCas9 | negative selection | 7440752 | 24215641 | 24215664 | 14 | - | 27260156 | MEWO | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.34362356212554507 | [763] | [615,548,534] | -6 | hSpCas9 | negative selection | 7494841 | 24215761 | 24215784 | 14 | + | 27260156 | MEWO | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.16909695358445545 | [418] | [568,438,338] | 4 | hSpCas9 | negative selection | 7494842 | 24215784 | 24215807 | 14 | - | 27260156 | MEWO | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.050538548764268304 | [417] | [307,432,454] | 1 | hSpCas9 | negative selection | 7494843 | 24215641 | 24215664 | 14 | - | 27260156 | MEWO | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.34362356212554507 | [763] | [615,548,534] | -6 | hSpCas9 | negative selection | 7497743 | 24215610 | 24215633 | 14 | - | 27260156 | MEWO | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.043804109879568065 | [226] | [215,195,207] | -1 | hSpCas9 | negative selection | 7559099 | 24214553 | 24214576 | 14 | + | 27260156 | MEWO | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.4391869050344378 | [435] | [353,255,302] | -7 | hSpCas9 | negative selection | 7559100 | 24214582 | 24214605 | 14 | - | 27260156 | MEWO | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.08734984511080243 | [581] | [579,611,357] | -2 | hSpCas9 | negative selection | 7559101 | 24215610 | 24215633 | 14 | - | 27260156 | MEWO | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.043804109879568065 | [226] | [215,195,207] | -1 | hSpCas9 | negative selection | 7562001 | 24214516 | 24214539 | 14 | - | 27260156 | MEWO | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.14456597428026496 | [1355] | [1267,1155,1041] | -3 | hSpCas9 | negative selection | 7562002 | 24214557 | 24214580 | 14 | + | 27260156 | MEWO | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -1.5733072608593481 | [39] | [18,5,13] | -9 | hSpCas9 | negative selection | 7562003 | 24215641 | 24215664 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.5583523208086758 | [763] | [489,514,407,453] | -7 | hSpCas9 | negative selection | 7616092 | 24215761 | 24215784 | 14 | + | 27260156 | LNCAPCLONEFGC | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.17875554412981173 | [418] | [262,342,402,342] | -3 | hSpCas9 | negative selection | 7616093 | 24215784 | 24215807 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.2878371945637491 | [417] | [447,324,663,450] | 4 | hSpCas9 | negative selection | 7616094 | 24215641 | 24215664 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.5583523208086758 | [763] | [489,514,407,453] | -7 | hSpCas9 | negative selection | 7618994 | 24215610 | 24215633 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.3378418402684581 | [226] | [266,205,422,170] | 5 | hSpCas9 | negative selection | 7680350 | 24214553 | 24214576 | 14 | + | 27260156 | LNCAPCLONEFGC | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.001027154168745839 | [435] | [358,447,383,382] | 0 | hSpCas9 | negative selection | 7680351 | 24214582 | 24214605 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.518359051351987 | [581] | [325,325,430,401] | -7 | hSpCas9 | negative selection | 7680352 | 24215610 | 24215633 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.3378418402684581 | [226] | [266,205,422,170] | 5 | hSpCas9 | negative selection | 7683252 | 24214516 | 24214539 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2706501601557625 | [1355] | [1037,871,1243,960] | -4 | hSpCas9 | negative selection | 7683253 | 24214557 | 24214580 | 14 | + | 27260156 | LNCAPCLONEFGC | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.49219756738080633 | [39] | [6,38,55,4] | -6 | hSpCas9 | negative selection | 7683254 | 24215641 | 24215664 | 14 | - | 27260156 | PANC0327 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.019310752164609424 | [763] | [1100,677,503,502] | 0 | hSpCas9 | negative selection | 7737343 | 24215761 | 24215784 | 14 | + | 27260156 | PANC0327 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.27870173878039795 | [418] | [295,317,370,239] | -4 | hSpCas9 | negative selection | 7737344 | 24215784 | 24215807 | 14 | - | 27260156 | PANC0327 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.06384756459060212 | [417] | [409,410,264,331] | -1 | hSpCas9 | negative selection | 7737345 | 24215641 | 24215664 | 14 | - | 27260156 | PANC0327 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.019310752164609424 | [763] | [1100,677,503,502] | 0 | hSpCas9 | negative selection | 7740245 | 24215610 | 24215633 | 14 | - | 27260156 | PANC0327 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.43046623292732344 | [226] | [141,108,131,219] | -6 | hSpCas9 | negative selection | 7801601 | 24214553 | 24214576 | 14 | + | 27260156 | PANC0327 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.2777121136004048 | [435] | [1185,187,368,229] | 4 | hSpCas9 | negative selection | 7801602 | 24214582 | 24214605 | 14 | - | 27260156 | PANC0327 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.22185263100854302 | [581] | [344,615,527,253] | -3 | hSpCas9 | negative selection | 7801603 | 24215610 | 24215633 | 14 | - | 27260156 | PANC0327 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.43046623292732344 | [226] | [141,108,131,219] | -6 | hSpCas9 | negative selection | 7804503 | 24214516 | 24214539 | 14 | - | 27260156 | PANC0327 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.08617245999633272 | [1355] | [1490,1039,1107,940] | -1 | hSpCas9 | negative selection | 7804504 | 24214557 | 24214580 | 14 | + | 27260156 | PANC0327 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.07098347386034076 | [39] | [61,30,39,4] | -1 | hSpCas9 | negative selection | 7804505 | 24215641 | 24215664 | 14 | - | 27260156 | NCIH2009 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.09573526874614247 | [763] | [1248,966,828] | -1 | hSpCas9 | negative selection | 7858594 | 24215761 | 24215784 | 14 | + | 27260156 | NCIH2009 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.25003676411507925 | [418] | [600,892,570] | 3 | hSpCas9 | negative selection | 7858595 | 24215784 | 24215807 | 14 | - | 27260156 | NCIH2009 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.03126701049371783 | [417] | [791,485,551] | 0 | hSpCas9 | negative selection | 7858596 | 24215641 | 24215664 | 14 | - | 27260156 | NCIH2009 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.09573526874614247 | [763] | [1248,966,828] | -1 | hSpCas9 | negative selection | 7861496 | 24215610 | 24215633 | 14 | - | 27260156 | NCIH2009 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.36895471700278426 | [226] | [321,159,270] | -5 | hSpCas9 | negative selection | 7922852 | 24214553 | 24214576 | 14 | + | 27260156 | NCIH2009 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.13841206913524542 | [435] | [665,530,814] | 2 | hSpCas9 | negative selection | 7922853 | 24214582 | 24214605 | 14 | - | 27260156 | NCIH2009 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2689309605557661 | [581] | [1074,482,547] | -4 | hSpCas9 | negative selection | 7922854 | 24215610 | 24215633 | 14 | - | 27260156 | NCIH2009 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.36895471700278426 | [226] | [321,159,270] | -5 | hSpCas9 | negative selection | 7925754 | 24214516 | 24214539 | 14 | - | 27260156 | NCIH2009 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.19754154249084865 | [1355] | [1599,1388,1958] | -3 | hSpCas9 | negative selection | 7925755 | 24214557 | 24214580 | 14 | + | 27260156 | NCIH2009 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -1.2496139051054937 | [39] | [29,9,31] | -8 | hSpCas9 | negative selection | 7925756 | 24215641 | 24215664 | 14 | - | 27260156 | NCIH1373 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.6885963418021933 | [763] | [629,524,462,136] | -6 | hSpCas9 | negative selection | 7979845 | 24215761 | 24215784 | 14 | + | 27260156 | NCIH1373 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.6806031561652301 | [418] | [787,313,869,290] | 6 | hSpCas9 | negative selection | 7979846 | 24215784 | 24215807 | 14 | - | 27260156 | NCIH1373 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.6289551747235531 | [417] | [612,744,812,183] | 6 | hSpCas9 | negative selection | 7979847 | 24215641 | 24215664 | 14 | - | 27260156 | NCIH1373 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.6885963418021933 | [763] | [629,524,462,136] | -6 | hSpCas9 | negative selection | 7982747 | 24215610 | 24215633 | 14 | - | 27260156 | NCIH1373 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.07491013612933295 | [226] | [301,253,181,61] | 0 | hSpCas9 | negative selection | 8044103 | 24214553 | 24214576 | 14 | + | 27260156 | NCIH1373 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.06555365020624629 | [435] | [647,297,696,65] | 0 | hSpCas9 | negative selection | 8044104 | 24214582 | 24214605 | 14 | - | 27260156 | NCIH1373 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.9282154278768413 | [581] | [327,305,270,124] | -7 | hSpCas9 | negative selection | 8044105 | 24215610 | 24215633 | 14 | - | 27260156 | NCIH1373 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.07491013612933295 | [226] | [301,253,181,61] | 0 | hSpCas9 | negative selection | 8047005 | 24214516 | 24214539 | 14 | - | 27260156 | NCIH1373 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -1.012558116167538 | [1355] | [838,675,709,212] | -8 | hSpCas9 | negative selection | 8047006 | 24214557 | 24214580 | 14 | + | 27260156 | NCIH1373 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -1.9207749220497234 | [39] | [21,18,2,0] | -9 | hSpCas9 | negative selection | 8047007 | 24215641 | 24215664 | 14 | - | 27260156 | PATU8902 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.15266895667068137 | [763] | [806,902,958,1179] | -1 | hSpCas9 | negative selection | 8101096 | 24215761 | 24215784 | 14 | + | 27260156 | PATU8902 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.4769030988804238 | [418] | [616,551,1115,888] | 5 | hSpCas9 | negative selection | 8101097 | 24215784 | 24215807 | 14 | - | 27260156 | PATU8902 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.5561048610618632 | [417] | [989,901,615,984] | 6 | hSpCas9 | negative selection | 8101098 | 24215641 | 24215664 | 14 | - | 27260156 | PATU8902 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.15266895667068137 | [763] | [806,902,958,1179] | -1 | hSpCas9 | negative selection | 8103998 | 24215610 | 24215633 | 14 | - | 27260156 | PATU8902 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.07253962927584956 | [226] | [520,340,239,234] | 0 | hSpCas9 | negative selection | 8165354 | 24214553 | 24214576 | 14 | + | 27260156 | PATU8902 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.37260927880666805 | [435] | [458,470,403,566] | -4 | hSpCas9 | negative selection | 8165355 | 24214582 | 24214605 | 14 | - | 27260156 | PATU8902 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.31235900120637483 | [581] | [591,803,687,494] | -3 | hSpCas9 | negative selection | 8165356 | 24215610 | 24215633 | 14 | - | 27260156 | PATU8902 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.07253962927584956 | [226] | [520,340,239,234] | 0 | hSpCas9 | negative selection | 8168256 | 24214516 | 24214539 | 14 | - | 27260156 | PATU8902 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.07416842052297135 | [1355] | [2024,1750,1753,1616] | 0 | hSpCas9 | negative selection | 8168257 | 24214557 | 24214580 | 14 | + | 27260156 | PATU8902 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.9904282512717639 | [39] | [19,10,65,1] | -7 | hSpCas9 | negative selection | 8168258 | 24215641 | 24215664 | 14 | - | 27260156 | PANC1 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2552479515391662 | [763] | [514,735,473,509] | -4 | hSpCas9 | negative selection | 8222347 | 24215761 | 24215784 | 14 | + | 27260156 | PANC1 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.12916268276484488 | [418] | [395,595,348,285] | 2 | hSpCas9 | negative selection | 8222348 | 24215784 | 24215807 | 14 | - | 27260156 | PANC1 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.04371250264010207 | [417] | [512,432,323,235] | 0 | hSpCas9 | negative selection | 8222349 | 24215641 | 24215664 | 14 | - | 27260156 | PANC1 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2552479515391662 | [763] | [514,735,473,509] | -4 | hSpCas9 | negative selection | 8225249 | 24215610 | 24215633 | 14 | - | 27260156 | PANC1 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.18292134649074177 | [226] | [100,262,165,173] | -3 | hSpCas9 | negative selection | 8286605 | 24214553 | 24214576 | 14 | + | 27260156 | PANC1 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.5967600532102331 | [435] | [221,304,233,238] | -7 | hSpCas9 | negative selection | 8286606 | 24214582 | 24214605 | 14 | - | 27260156 | PANC1 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.5344040488505044 | [581] | [392,403,315,282] | -7 | hSpCas9 | negative selection | 8286607 | 24215610 | 24215633 | 14 | - | 27260156 | PANC1 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.18292134649074177 | [226] | [100,262,165,173] | -3 | hSpCas9 | negative selection | 8289507 | 24214516 | 24214539 | 14 | - | 27260156 | PANC1 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | 0.1305602277697515 | [1355] | [1439,1135,1256,1221] | 2 | hSpCas9 | negative selection | 8289508 | 24214557 | 24214580 | 14 | + | 27260156 | PANC1 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -2.6511862684450627 | [39] | [7,12,1,0] | -9 | hSpCas9 | negative selection | 8289509 | 24215641 | 24215664 | 14 | - | 27260156 | PANC0813 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.04757644379491177 | [763] | [757,1003,807,889] | -1 | hSpCas9 | negative selection | 8343598 | 24215761 | 24215784 | 14 | + | 27260156 | PANC0813 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.27419480323461964 | [418] | [658,638,471,613] | 4 | hSpCas9 | negative selection | 8343599 | 24215784 | 24215807 | 14 | - | 27260156 | PANC0813 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.14699002981700748 | [417] | [462,538,410,365] | -2 | hSpCas9 | negative selection | 8343600 | 24215641 | 24215664 | 14 | - | 27260156 | PANC0813 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.04757644379491177 | [763] | [757,1003,807,889] | -1 | hSpCas9 | negative selection | 8346500 | 24215610 | 24215633 | 14 | - | 27260156 | PANC0813 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.2826597958110484 | [226] | [461,185,272,384] | 4 | hSpCas9 | negative selection | 8407856 | 24214553 | 24214576 | 14 | + | 27260156 | PANC0813 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.00696464777904543 | [435] | [385,646,599,399] | 0 | hSpCas9 | negative selection | 8407857 | 24214582 | 24214605 | 14 | - | 27260156 | PANC0813 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.05118985296232981 | [581] | [570,556,827,673] | -1 | hSpCas9 | negative selection | 8407858 | 24215610 | 24215633 | 14 | - | 27260156 | PANC0813 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.2826597958110484 | [226] | [461,185,272,384] | 4 | hSpCas9 | negative selection | 8410758 | 24214516 | 24214539 | 14 | - | 27260156 | PANC0813 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | 0.06674284967666755 | [1355] | [1878,1487,2105,1242] | 1 | hSpCas9 | negative selection | 8410759 | 24214557 | 24214580 | 14 | + | 27260156 | PANC0813 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.2913767450152931 | [39] | [40,13,96,3] | -4 | hSpCas9 | negative selection | 8410760 | 24215641 | 24215664 | 14 | - | 27260156 | RDES | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.038914253986395475 | [763] | [738,780,1029,887] | 0 | hSpCas9 | negative selection | 8464849 | 24215761 | 24215784 | 14 | + | 27260156 | RDES | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.26097383255004897 | [418] | [525,533,640,612] | 4 | hSpCas9 | negative selection | 8464850 | 24215784 | 24215807 | 14 | - | 27260156 | RDES | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.4016051317752246 | [417] | [575,651,721,573] | 6 | hSpCas9 | negative selection | 8464851 | 24215641 | 24215664 | 14 | - | 27260156 | RDES | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.038914253986395475 | [763] | [738,780,1029,887] | 0 | hSpCas9 | negative selection | 8467751 | 24215610 | 24215633 | 14 | - | 27260156 | RDES | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.019175833420233657 | [226] | [221,220,391,193] | 0 | hSpCas9 | negative selection | 8529107 | 24214553 | 24214576 | 14 | + | 27260156 | RDES | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.22603866961728855 | [435] | [527,441,545,881] | 3 | hSpCas9 | negative selection | 8529108 | 24214582 | 24214605 | 14 | - | 27260156 | RDES | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.4167735158695229 | [581] | [521,460,533,465] | -6 | hSpCas9 | negative selection | 8529109 | 24215610 | 24215633 | 14 | - | 27260156 | RDES | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.019175833420233657 | [226] | [221,220,391,193] | 0 | hSpCas9 | negative selection | 8532009 | 24214516 | 24214539 | 14 | - | 27260156 | RDES | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.12710457019155164 | [1355] | [1099,1276,1436,2034] | -2 | hSpCas9 | negative selection | 8532010 | 24214557 | 24214580 | 14 | + | 27260156 | RDES | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -1.1056024794443067 | [39] | [10,29,19,25] | -9 | hSpCas9 | negative selection | 8532011 | 24215641 | 24215664 | 14 | - | 27260156 | PC3 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2100610697730661 | [763] | [363,574,1432,639] | -5 | hSpCas9 | negative selection | 8586100 | 24215761 | 24215784 | 14 | + | 27260156 | PC3 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.30167503063709317 | [418] | [312,566,1028,380] | 6 | hSpCas9 | negative selection | 8586101 | 24215784 | 24215807 | 14 | - | 27260156 | PC3 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.035415533522192816 | [417] | [276,522,483,376] | -1 | hSpCas9 | negative selection | 8586102 | 24215641 | 24215664 | 14 | - | 27260156 | PC3 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2100610697730661 | [763] | [363,574,1432,639] | -5 | hSpCas9 | negative selection | 8589002 | 24215610 | 24215633 | 14 | - | 27260156 | PC3 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.09311784003512291 | [226] | [151,173,430,180] | -2 | hSpCas9 | negative selection | 8650358 | 24214553 | 24214576 | 14 | + | 27260156 | PC3 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.5145757864519778 | [435] | [198,231,533,363] | -8 | hSpCas9 | negative selection | 8650359 | 24214582 | 24214605 | 14 | - | 27260156 | PC3 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.24248878848152694 | [581] | [290,535,744,528] | -5 | hSpCas9 | negative selection | 8650360 | 24215610 | 24215633 | 14 | - | 27260156 | PC3 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.09311784003512291 | [226] | [151,173,430,180] | -2 | hSpCas9 | negative selection | 8653260 | 24214516 | 24214539 | 14 | - | 27260156 | PC3 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.23149307406042352 | [1355] | [622,1236,2149,1109] | -5 | hSpCas9 | negative selection | 8653261 | 24214557 | 24214580 | 14 | + | 27260156 | PC3 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.4622338044384362 | [39] | [7,44,83,5] | -8 | hSpCas9 | negative selection | 8653262 | 24215641 | 24215664 | 14 | - | 27260156 | PATU8988T | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2500215066635257 | [763] | [362,586,737,804] | -4 | hSpCas9 | negative selection | 8707351 | 24215761 | 24215784 | 14 | + | 27260156 | PATU8988T | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.10616693225106145 | [418] | [382,532,436,395] | 1 | hSpCas9 | negative selection | 8707352 | 24215784 | 24215807 | 14 | - | 27260156 | PATU8988T | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.0071273015466443435 | [417] | [389,326,364,545] | 0 | hSpCas9 | negative selection | 8707353 | 24215641 | 24215664 | 14 | - | 27260156 | PATU8988T | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2500215066635257 | [763] | [362,586,737,804] | -4 | hSpCas9 | negative selection | 8710253 | 24215610 | 24215633 | 14 | - | 27260156 | PATU8988T | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.3185369472599202 | [226] | [114,124,215,247] | -5 | hSpCas9 | negative selection | 8771609 | 24214553 | 24214576 | 14 | + | 27260156 | PATU8988T | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.5981776363291373 | [435] | [222,322,186,394] | -7 | hSpCas9 | negative selection | 8771610 | 24214582 | 24214605 | 14 | - | 27260156 | PATU8988T | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2771239336097201 | [581] | [230,495,679,447] | -5 | hSpCas9 | negative selection | 8771611 | 24215610 | 24215633 | 14 | - | 27260156 | PATU8988T | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.3185369472599202 | [226] | [114,124,215,247] | -5 | hSpCas9 | negative selection | 8774511 | 24214516 | 24214539 | 14 | - | 27260156 | PATU8988T | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | 0.01778073710159611 | [1355] | [1107,1566,1174,1493] | 0 | hSpCas9 | negative selection | 8774512 | 24214557 | 24214580 | 14 | + | 27260156 | PATU8988T | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.8470654020491111 | [39] | [15,27,6,36] | -8 | hSpCas9 | negative selection | 8774513 | 24215641 | 24215664 | 14 | - | 27260156 | T47D | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.041319871216878745 | [763] | [1013,876,799,979] | 0 | hSpCas9 | negative selection | 8828602 | 24215761 | 24215784 | 14 | + | 27260156 | T47D | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.17923822579027393 | [418] | [624,415,559,623] | 4 | hSpCas9 | negative selection | 8828603 | 24215784 | 24215807 | 14 | - | 27260156 | T47D | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.00505808553543069 | [417] | [526,472,427,515] | 0 | hSpCas9 | negative selection | 8828604 | 24215641 | 24215664 | 14 | - | 27260156 | T47D | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.041319871216878745 | [763] | [1013,876,799,979] | 0 | hSpCas9 | negative selection | 8831504 | 24215610 | 24215633 | 14 | - | 27260156 | T47D | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.16900371356892585 | [226] | [336,275,269,308] | 3 | hSpCas9 | negative selection | 8892860 | 24214553 | 24214576 | 14 | + | 27260156 | T47D | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.4439713152463516 | [435] | [363,298,369,469] | -7 | hSpCas9 | negative selection | 8892861 | 24214582 | 24214605 | 14 | - | 27260156 | T47D | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.14563910393325802 | [581] | [571,566,658,657] | -3 | hSpCas9 | negative selection | 8892862 | 24215610 | 24215633 | 14 | - | 27260156 | T47D | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.16900371356892585 | [226] | [336,275,269,308] | 3 | hSpCas9 | negative selection | 8895762 | 24214516 | 24214539 | 14 | - | 27260156 | T47D | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.12101975170094859 | [1355] | [1614,1243,1410,1562] | -3 | hSpCas9 | negative selection | 8895763 | 24214557 | 24214580 | 14 | + | 27260156 | T47D | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.35133808585834636 | [39] | [26,23,54,40] | -6 | hSpCas9 | negative selection | 8895764 | 24215641 | 24215664 | 14 | - | 27260156 | SU8686 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.0751536550231523 | [763] | [642,538,965,769] | -1 | hSpCas9 | negative selection | 8949853 | 24215761 | 24215784 | 14 | + | 27260156 | SU8686 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.26942022455392517 | [418] | [355,467,541,684] | 4 | hSpCas9 | negative selection | 8949854 | 24215784 | 24215807 | 14 | - | 27260156 | SU8686 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.007590400842055145 | [417] | [397,292,553,444] | 0 | hSpCas9 | negative selection | 8949855 | 24215641 | 24215664 | 14 | - | 27260156 | SU8686 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.0751536550231523 | [763] | [642,538,965,769] | -1 | hSpCas9 | negative selection | 8952755 | 24215610 | 24215633 | 14 | - | 27260156 | SU8686 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.613484980460133 | [226] | [87,129,237,141] | -7 | hSpCas9 | negative selection | 9014111 | 24214553 | 24214576 | 14 | + | 27260156 | SU8686 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.1890929565698502 | [435] | [255,376,358,565] | -3 | hSpCas9 | negative selection | 9014112 | 24214582 | 24214605 | 14 | - | 27260156 | SU8686 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.23246194502922246 | [581] | [305,484,531,693] | -4 | hSpCas9 | negative selection | 9014113 | 24215610 | 24215633 | 14 | - | 27260156 | SU8686 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.613484980460133 | [226] | [87,129,237,141] | -7 | hSpCas9 | negative selection | 9017013 | 24214516 | 24214539 | 14 | - | 27260156 | SU8686 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.3009591357209471 | [1355] | [1041,869,1009,1539] | -5 | hSpCas9 | negative selection | 9017014 | 24214557 | 24214580 | 14 | + | 27260156 | SU8686 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.2807054649520526 | [39] | [14,22,41,57] | -5 | hSpCas9 | negative selection | 9017015 | 24215641 | 24215664 | 14 | - | 27260156 | SKES1 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.06652810207490212 | [763] | [785,886,765,758] | 1 | hSpCas9 | negative selection | 9071104 | 24215761 | 24215784 | 14 | + | 27260156 | SKES1 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.1643382039360888 | [418] | [432,391,494,526] | 3 | hSpCas9 | negative selection | 9071105 | 24215784 | 24215807 | 14 | - | 27260156 | SKES1 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.22620813596321915 | [417] | [657,463,448,405] | 5 | hSpCas9 | negative selection | 9071106 | 24215641 | 24215664 | 14 | - | 27260156 | SKES1 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.06652810207490212 | [763] | [785,886,765,758] | 1 | hSpCas9 | negative selection | 9074006 | 24215610 | 24215633 | 14 | - | 27260156 | SKES1 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.005796984256830395 | [226] | [361,166,162,220] | 0 | hSpCas9 | negative selection | 9135362 | 24214553 | 24214576 | 14 | + | 27260156 | SKES1 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.6691638872389558 | [435] | [299,242,366,189] | -9 | hSpCas9 | negative selection | 9135363 | 24214582 | 24214605 | 14 | - | 27260156 | SKES1 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.26690828115624887 | [581] | [770,538,341,338] | -5 | hSpCas9 | negative selection | 9135364 | 24215610 | 24215633 | 14 | - | 27260156 | SKES1 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.005796984256830395 | [226] | [361,166,162,220] | 0 | hSpCas9 | negative selection | 9138264 | 24214516 | 24214539 | 14 | - | 27260156 | SKES1 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2708807596189917 | [1355] | [1047,1404,1235,839] | -5 | hSpCas9 | negative selection | 9138265 | 24214557 | 24214580 | 14 | + | 27260156 | SKES1 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -1.3863432496041108 | [39] | [16,24,10,9] | -9 | hSpCas9 | negative selection | 9138266 | 24215641 | 24215664 | 14 | - | 27260156 | TOV112D | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.05614896400475222 | [763] | [973,724,808,673] | 1 | hSpCas9 | negative selection | 9192355 | 24215761 | 24215784 | 14 | + | 27260156 | TOV112D | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.1366022370685562 | [418] | [455,570,309,245] | -3 | hSpCas9 | negative selection | 9192356 | 24215784 | 24215807 | 14 | - | 27260156 | TOV112D | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.03713989038719584 | [417] | [410,463,366,480] | 0 | hSpCas9 | negative selection | 9192357 | 24215641 | 24215664 | 14 | - | 27260156 | TOV112D | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.05614896400475222 | [763] | [973,724,808,673] | 1 | hSpCas9 | negative selection | 9195257 | 24215610 | 24215633 | 14 | - | 27260156 | TOV112D | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2523898842103989 | [226] | [257,188,190,131] | -5 | hSpCas9 | negative selection | 9256613 | 24214553 | 24214576 | 14 | + | 27260156 | TOV112D | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.12152818231876077 | [435] | [233,405,415,796] | 2 | hSpCas9 | negative selection | 9256614 | 24214582 | 24214605 | 14 | - | 27260156 | TOV112D | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.037622488798431886 | [581] | [693,750,373,508] | 0 | hSpCas9 | negative selection | 9256615 | 24215610 | 24215633 | 14 | - | 27260156 | TOV112D | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2523898842103989 | [226] | [257,188,190,131] | -5 | hSpCas9 | negative selection | 9259515 | 24214516 | 24214539 | 14 | - | 27260156 | TOV112D | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.1326923925213519 | [1355] | [1404,1452,1186,981] | -3 | hSpCas9 | negative selection | 9259516 | 24214557 | 24214580 | 14 | + | 27260156 | TOV112D | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | 0.722433066850463 | [39] | [0,76,26,153] | 9 | hSpCas9 | negative selection | 9259517 | 24215641 | 24215664 | 14 | - | 27260156 | TC71 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.21822499476661272 | [763] | [997,900,982,924] | 5 | hSpCas9 | negative selection | 9313606 | 24215761 | 24215784 | 14 | + | 27260156 | TC71 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | 0.26116482763381754 | [418] | [506,483,581,581] | 6 | hSpCas9 | negative selection | 9313607 | 24215784 | 24215807 | 14 | - | 27260156 | TC71 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.09142729931408061 | [417] | [352,382,496,449] | -2 | hSpCas9 | negative selection | 9313608 | 24215641 | 24215664 | 14 | - | 27260156 | TC71 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | 0.21822499476661272 | [763] | [997,900,982,924] | 5 | hSpCas9 | negative selection | 9316508 | 24215610 | 24215633 | 14 | - | 27260156 | TC71 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.23585301197208186 | [226] | [212,281,136,195] | -6 | hSpCas9 | negative selection | 9377864 | 24214553 | 24214576 | 14 | + | 27260156 | TC71 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.4431918311337927 | [435] | [262,384,437,283] | -8 | hSpCas9 | negative selection | 9377865 | 24214582 | 24214605 | 14 | - | 27260156 | TC71 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.18074323265268816 | [581] | [646,586,515,443] | -5 | hSpCas9 | negative selection | 9377866 | 24215610 | 24215633 | 14 | - | 27260156 | TC71 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | -0.23585301197208186 | [226] | [212,281,136,195] | -6 | hSpCas9 | negative selection | 9380766 | 24214516 | 24214539 | 14 | - | 27260156 | TC71 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.07562519746038388 | [1355] | [1486,1359,1237,1437] | -2 | hSpCas9 | negative selection | 9380767 | 24214557 | 24214580 | 14 | + | 27260156 | TC71 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.7917636271473176 | [39] | [31,33,12,19] | -9 | hSpCas9 | negative selection | 9380768 | 24215641 | 24215664 | 14 | - | 27260156 | TC32 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.253992540141799 | [763] | [555,485,708,693] | -4 | hSpCas9 | negative selection | 9434857 | 24215761 | 24215784 | 14 | + | 27260156 | TC32 | viability | ACGTGCGTGTCGACCCAGAAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.2077835377353868 | [418] | [472,138,385,417] | -4 | hSpCas9 | negative selection | 9434858 | 24215784 | 24215807 | 14 | - | 27260156 | TC32 | viability | CTCTCGCAGATTACACTCTCTGG | NEDD8-MDP1 | ENSG00000255526 | 0.3790122232033337 | [417] | [406,502,618,516] | 6 | hSpCas9 | negative selection | 9434859 | 24215641 | 24215664 | 14 | - | 27260156 | TC32 | viability | GTGATGGAACTGTACGAGATAGG | NEDD8-MDP1 | ENSG00000255526 | -0.253992540141799 | [763] | [555,485,708,693] | -4 | hSpCas9 | negative selection | 9437759 | 24215610 | 24215633 | 14 | - | 27260156 | TC32 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.03466781616461656 | [226] | [197,253,222,170] | 0 | hSpCas9 | negative selection | 9499115 | 24214553 | 24214576 | 14 | + | 27260156 | TC32 | viability | GGTCAAAGAGCTCCAGTAGCTGG | NEDD8-MDP1 | ENSG00000255526 | -0.3890306929609224 | [435] | [333,236,345,348] | -6 | hSpCas9 | negative selection | 9499116 | 24214582 | 24214605 | 14 | - | 27260156 | TC32 | viability | TGCAGGACAAGTGAGATAGAAGG | NEDD8-MDP1 | ENSG00000255526 | -0.4162157582823962 | [581] | [227,451,507,451] | -7 | hSpCas9 | negative selection | 9499117 | 24215610 | 24215633 | 14 | - | 27260156 | TC32 | viability | AGACGTCCGACTGTACCCAGAGG | NEDD8-MDP1 | ENSG00000255526 | 0.03466781616461656 | [226] | [197,253,222,170] | 0 | hSpCas9 | negative selection | 9502017 | 24214516 | 24214539 | 14 | - | 27260156 | TC32 | viability | GTTCATCGGGAAATCTATCCAGG | NEDD8-MDP1 | ENSG00000255526 | -0.06034151748962957 | [1355] | [1041,1117,1415,1337] | -1 | hSpCas9 | negative selection | 9502018 | 24214557 | 24214580 | 14 | + | 27260156 | TC32 | viability | AAAGAGCTCCAGTAGCTGGTTGG | NEDD8-MDP1 | ENSG00000255526 | -0.660378163603041 | [39] | [3,23,35,34] | -8 | hSpCas9 | negative selection | 9502019 |