| 29485752 | 29485775 | 22 | + | 26472758 | Jiyoye | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -0.2742951000686291 | [84] | [52] | -2 | hSpCas9 | negative selection | 107589 | 29485752 | 29485775 | 22 | + | 26472758 | KBM7 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -0.31656169895892144 | [345,374] | [149,125] | -3 | hSpCas9 | negative selection | 298707 | 29485752 | 29485775 | 22 | + | 26472758 | Raji | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -0.799507060234919 | [89] | [11] | -6 | hSpCas9 | negative selection | 489825 | 29485752 | 29485775 | 22 | + | 26472758 | K562 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -0.22163193753171936 | [354] | [256] | -1 | hSpCas9 | negative selection | 680943 | 29483415 | 29483438 | 22 | + | 26627737 | DLD1 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.45608314532346084 | [301] | [208,93,89] | 4 | hSpCas9 | negative selection | 817248 | 29483418 | 29483441 | 22 | + | 26627737 | DLD1 | viability | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | -0.07658514751831369 | [117] | [18,70,18] | -1 | hSpCas9 | negative selection | 817249 | 29483415 | 29483438 | 22 | + | 26627737 | GBM cells | viability after 5 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.021915911680706834 | [194] | [95,109] | 0 | hSpCas9 | negative selection | 899563 | 29483418 | 29483441 | 22 | + | 26627737 | GBM cells | viability after 5 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | -0.2937312030567103 | [79] | [29,39] | -4 | hSpCas9 | negative selection | 899564 | 29483415 | 29483438 | 22 | + | 26627737 | GBM cells | viability after 13 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.36558577472623827 | [194] | [148,125] | 5 | hSpCas9 | negative selection | 981878 | 29483418 | 29483441 | 22 | + | 26627737 | GBM cells | viability after 13 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.5023445154848833 | [79] | [66,56] | 6 | hSpCas9 | negative selection | 981879 | 29483415 | 29483438 | 22 | + | 26627737 | GBM cells | viability after 21 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.5515073144683955 | [194] | [148,160] | 5 | hSpCas9 | negative selection | 1064193 | 29483418 | 29483441 | 22 | + | 26627737 | GBM cells | viability after 21 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | -0.050904842239537285 | [79] | [42,40] | 0 | hSpCas9 | negative selection | 1064194 | 29483415 | 29483438 | 22 | + | 26627737 | RPE1 | viability after 9 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.16079583236858125 | [673] | [241,227] | 1 | hSpCas9 | negative selection | 1146508 | 29483418 | 29483441 | 22 | + | 26627737 | RPE1 | viability after 9 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.8178676388546406 | [179] | [142,42] | 5 | hSpCas9 | negative selection | 1146509 | 29483415 | 29483438 | 22 | + | 26627737 | RPE1 | viability after 12 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.1359241011974139 | [673] | [214,181] | 0 | hSpCas9 | negative selection | 1228823 | 29483418 | 29483441 | 22 | + | 26627737 | RPE1 | viability after 12 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.17357668580243435 | [179] | [72,34] | 1 | hSpCas9 | negative selection | 1228824 | 29483415 | 29483438 | 22 | + | 26627737 | RPE1 | viability after 15 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.3662514661412616 | [673] | [202,286] | 2 | hSpCas9 | negative selection | 1311138 | 29483418 | 29483441 | 22 | + | 26627737 | RPE1 | viability after 15 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.45502285114815555 | [179] | [52,85] | 3 | hSpCas9 | negative selection | 1311139 | 29483415 | 29483438 | 22 | + | 26627737 | RPE1 | viability after 18 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.22724343131898922 | [673] | [151,158] | -1 | hSpCas9 | negative selection | 1393453 | 29483418 | 29483441 | 22 | + | 26627737 | RPE1 | viability after 18 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 1.0437211218861857 | [179] | [147,48] | 6 | hSpCas9 | negative selection | 1393454 | 29483415 | 29483438 | 22 | + | 26627737 | HeLa | viability after 8 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.2545074458856035 | [345] | [130,67,176] | -2 | hSpCas9 | negative selection | 1475768 | 29483418 | 29483441 | 22 | + | 26627737 | HeLa | viability after 8 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.021022330390826127 | [88] | [38,56,22] | 0 | hSpCas9 | negative selection | 1475769 | 29483415 | 29483438 | 22 | + | 26627737 | HeLa | viability after 12 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.49224374691047396 | [345] | [77,141,79] | -4 | hSpCas9 | negative selection | 1558083 | 29483418 | 29483441 | 22 | + | 26627737 | HeLa | viability after 12 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.36118208593041445 | [88] | [40,42,57] | 3 | hSpCas9 | negative selection | 1558084 | 29483415 | 29483438 | 22 | + | 26627737 | HeLa | viability after 15 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.6790288590808831 | [345] | [263,126,289] | 5 | hSpCas9 | negative selection | 1640398 | 29483418 | 29483441 | 22 | + | 26627737 | HeLa | viability after 15 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.2643656309135842 | [88] | [47,44,36] | 2 | hSpCas9 | negative selection | 1640399 | 29483415 | 29483438 | 22 | + | 26627737 | HeLa | viability after 18 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.648911064087192 | [345] | [168,103,289] | 5 | hSpCas9 | negative selection | 1722713 | 29483418 | 29483441 | 22 | + | 26627737 | HeLa | viability after 18 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.25726910564164696 | [88] | [31,36,36] | 2 | hSpCas9 | negative selection | 1722714 | 29483415 | 29483438 | 22 | + | 26627737 | HCT116 | viability after 6 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -1.6753517378425784 | [287] | [28,5] | -7 | hSpCas9 | negative selection | 1805028 | 29483418 | 29483441 | 22 | + | 26627737 | HCT116 | viability after 6 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | -3.656979314178404 | [188] | [2,1] | -9 | hSpCas9 | negative selection | 1805029 | 29483415 | 29483438 | 22 | + | 26627737 | HCT116 | viability after 8 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.12508066660617906 | [255] | [133,159,166] | 1 | hSpCas9 | negative selection | 1887343 | 29483418 | 29483441 | 22 | + | 26627737 | HCT116 | viability after 8 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.047565484954248394 | [140] | [67,118,53] | 0 | hSpCas9 | negative selection | 1887344 | 29483415 | 29483438 | 22 | + | 26627737 | HCT116 | viability after 9 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 1.0684820965720314 | [287] | [253,87] | 7 | hSpCas9 | negative selection | 1969658 | 29483418 | 29483441 | 22 | + | 26627737 | HCT116 | viability after 9 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 1.4868084594486417 | [188] | [141,140] | 8 | hSpCas9 | negative selection | 1969659 | 29483415 | 29483438 | 22 | + | 26627737 | HCT116 | viability after 12 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.34857414095094763 | [255] | [124,130,260] | 3 | hSpCas9 | negative selection | 2051973 | 29483418 | 29483441 | 22 | + | 26627737 | HCT116 | viability after 12 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | -0.010555106600098618 | [140] | [57,112,51] | 0 | hSpCas9 | negative selection | 2051974 | 29483415 | 29483438 | 22 | + | 26627737 | HCT116 | viability after 15 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.23260476293754073 | [255] | [108,189,210] | 2 | hSpCas9 | negative selection | 2134288 | 29483418 | 29483441 | 22 | + | 26627737 | HCT116 | viability after 15 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.1472097241937288 | [140] | [128,70,73] | 1 | hSpCas9 | negative selection | 2134289 | 29483415 | 29483438 | 22 | + | 26627737 | HCT116 | viability after 18 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.7020245743430531 | [255] | [183,199,220] | 6 | hSpCas9 | negative selection | 2216603 | 29483418 | 29483441 | 22 | + | 26627737 | HCT116 | viability after 18 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | -0.0679560059467128 | [140] | [96,26,73] | 0 | hSpCas9 | negative selection | 2216604 | 29485826 | 29485849 | | + | 24336571 | A375 | resistance to PLX after 7 days | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.006443215041870731 | [17,18] | [16,19] | 0 | hSpCas9 | positive selection | 3130267 | 29485775 | 29485798 | | - | 24336571 | A375 | resistance to PLX after 7 days | CTGGTATTCTCGCAGCTGGGCGG | NEFH | ENSG00000100285 | 0.8049891887707578 | [2,3] | [5,6] | 9 | hSpCas9 | positive selection | 3130268 | 29485826 | 29485849 | | + | 24336571 | A375 | resistance to PLX after 14 days | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.851320832667985 | [18,16] | [3,4] | -8 | hSpCas9 | positive selection | 3188060 | 29485775 | 29485798 | | - | 24336571 | A375 | resistance to PLX after 14 days | CTGGTATTCTCGCAGCTGGGCGG | NEFH | ENSG00000100285 | 0.5114490273823996 | [4,5] | [3,2] | 5 | hSpCas9 | positive selection | 3188061 | 29485826 | 29485849 | | + | 24336571 | A375 | viability after 7 days | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.3263546871306991 | [14] | [17,18] | 5 | hSpCas9 | negative selection | 3245853 | 29485775 | 29485798 | | - | 24336571 | A375 | viability after 7 days | CTGGTATTCTCGCAGCTGGGCGG | NEFH | ENSG00000100285 | -0.5110167615712418 | [5] | [2,3] | -6 | hSpCas9 | negative selection | 3245854 | 29485826 | 29485849 | | + | 24336571 | A375 | viability after 14 days | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.2917731247282653 | [14] | [18,16] | 4 | hSpCas9 | negative selection | 3303646 | 29485775 | 29485798 | | - | 24336571 | A375 | viability after 14 days | CTGGTATTCTCGCAGCTGGGCGG | NEFH | ENSG00000100285 | -0.04698776771036228 | [5] | [4,5] | 0 | hSpCas9 | negative selection | 3303647 | 29485826 | 29485849 | 22 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.8143827155971068 | [86,86] | [0,0] | 4 | hSpCas9 | positive selection | 3381415 | 29483373 | 29483396 | 22 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.537089654904271 | [221,221] | [0,0] | -4 | hSpCas9 | positive selection | 3381416 | 29488865 | 29488888 | 22 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.4244361972810935 | [113,113] | [0,0] | 2 | hSpCas9 | positive selection | 3381417 | 29488892 | 29488915 | 22 | + | 26780180 | HT29 | viability (Avana library 4 designs) | ATTCCTTTCTCGCTTCCAGAAGG | NEFH | ENSG00000100285 | 1.57722573313214 | [] | [] | 6 | hSpCas9 | negative selection | 3443041 | 29489005 | 29489028 | 22 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GATTGTGGAGGAACAGACAGAGG | NEFH | ENSG00000100285 | 1.24108069392814 | [] | [] | 5 | hSpCas9 | negative selection | 3443042 | 29489005 | 29489028 | 22 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GATTGTGGAGGAACAGACAGAGG | NEFH | ENSG00000100285 | 1.03437363717461 | [] | [] | 1 | hSpCas9 | negative selection | 3534539 | 29488892 | 29488915 | 22 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ATTCCTTTCTCGCTTCCAGAAGG | NEFH | ENSG00000100285 | -3.70227961729799 | [] | [] | -4 | hSpCas9 | negative selection | 3534540 | 29489005 | 29489028 | 22 | + | 26780180 | A375 | viability (Avana lentiGuide) | GATTGTGGAGGAACAGACAGAGG | NEFH | ENSG00000100285 | -0.629674298832943 | [] | [] | -1 | hSpCas9 | negative selection | 3643198 | 29488892 | 29488915 | 22 | + | 26780180 | A375 | viability (Avana lentiGuide) | ATTCCTTTCTCGCTTCCAGAAGG | NEFH | ENSG00000100285 | 5.40854578644356 | [] | [] | 5 | hSpCas9 | negative selection | 3643199 | 29489005 | 29489028 | 22 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GATTGTGGAGGAACAGACAGAGG | NEFH | ENSG00000100285 | -0.19584859649082043 | [5] | [4,4] | -3 | hSpCas9 | positive selection | 3751857 | 29488892 | 29488915 | 22 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ATTCCTTTCTCGCTTCCAGAAGG | NEFH | ENSG00000100285 | -0.19940784813399332 | [5] | [5,3] | -3 | hSpCas9 | positive selection | 3751858 | 29489005 | 29489028 | 22 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GATTGTGGAGGAACAGACAGAGG | NEFH | ENSG00000100285 | 0.26253073634675334 | [5] | [6,4] | 7 | hSpCas9 | positive selection | 3860464 | 29488892 | 29488915 | 22 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ATTCCTTTCTCGCTTCCAGAAGG | NEFH | ENSG00000100285 | -0.3326760311937035 | [6] | [4,3] | -4 | hSpCas9 | positive selection | 3860465 | 29483415 | 29483438 | 22 | + | 26780180 | A375 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.685955116988152 | [] | [] | 2 | hSpCas9 | negative selection | 3971783 | 29483373 | 29483396 | 22 | + | 26780180 | A375 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | 0.958830541713013 | [] | [] | 4 | hSpCas9 | negative selection | 3971784 | 29485826 | 29485849 | 22 | + | 26780180 | A375 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 1.13456158558643 | [] | [] | 6 | hSpCas9 | negative selection | 3971785 | 29488865 | 29488888 | 22 | + | 26780180 | A375 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.81209036825435 | [] | [] | 3 | hSpCas9 | negative selection | 3971786 | 29483415 | 29483438 | 22 | + | 26780180 | HT29 | viability (GeCKOv2 library) | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 1.57935626553811 | [] | [] | 8 | hSpCas9 | negative selection | 4079749 | 29483373 | 29483396 | 22 | + | 26780180 | HT29 | viability (GeCKOv2 library) | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | 1.40182472387162 | [] | [] | 7 | hSpCas9 | negative selection | 4079750 | 29485826 | 29485849 | 22 | + | 26780180 | HT29 | viability (GeCKOv2 library) | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 1.57234859952328 | [] | [] | 8 | hSpCas9 | negative selection | 4079751 | 29488865 | 29488888 | 22 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.470680485691633 | [] | [] | 1 | hSpCas9 | negative selection | 4079752 | 29485826 | 29485849 | 22 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.1616863424230665 | [3] | [2,1] | -4 | hSpCas9 | positive selection | 4154904 | 29485775 | 29485798 | 22 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CTGGTATTCTCGCAGCTGGGCGG | NEFH | ENSG00000100285 | -0.07402901439457665 | [2] | [0,1] | -2 | hSpCas9 | positive selection | 4154906 | 29485826 | 29485849 | 22 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.19623237491794351 | [2] | [0,3,0,0] | -3 | hSpCas9 | positive selection | 4218926 | 29485775 | 29485798 | 22 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CTGGTATTCTCGCAGCTGGGCGG | NEFH | ENSG00000100285 | 0.15867565319440513 | [1] | [0,0,0,0] | 1 | hSpCas9 | positive selection | 4218928 | 29483415 | 29483438 | 22 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.13240837620883378 | [2] | [2,1] | -3 | hSpCas9 | positive selection | 4285274 | 29485826 | 29485849 | 22 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.36205474058966997 | [2] | [3,1] | 7 | hSpCas9 | positive selection | 4349531 | 29483373 | 29483396 | 22 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | 0.254201227560794 | [3] | [3,2] | 5 | hSpCas9 | positive selection | 4349532 | 29488865 | 29488888 | 22 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.13884836091520877 | [2] | [2,1] | 3 | hSpCas9 | positive selection | 4349533 | 29483415 | 29483438 | 22 | + | 27260156 | BXPC3 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.21471862855384508 | [448] | [496,482,581,633] | 5 | hSpCas9 | negative selection | 5557734 | 29485826 | 29485849 | 22 | + | 27260156 | BXPC3 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.2908865935280974 | [303] | [279,277,258,210] | -6 | hSpCas9 | negative selection | 5621991 | 29483373 | 29483396 | 22 | + | 27260156 | BXPC3 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.029894716477484207 | [726] | [609,720,694,992] | 0 | hSpCas9 | negative selection | 5621992 | 29488865 | 29488888 | 22 | + | 27260156 | BXPC3 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.17091980217047387 | [243] | [212,322,268,355] | 4 | hSpCas9 | negative selection | 5621993 | 29483415 | 29483438 | 22 | + | 27260156 | A673 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.09336375999763946 | [448] | [607,378,486,564] | -2 | hSpCas9 | negative selection | 5678985 | 29485826 | 29485849 | 22 | + | 27260156 | A673 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.47509606114760294 | [303] | [190,265,335,246] | -8 | hSpCas9 | negative selection | 5743242 | 29483373 | 29483396 | 22 | + | 27260156 | A673 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.03361758074161225 | [726] | [831,859,889,822] | -1 | hSpCas9 | negative selection | 5743243 | 29488865 | 29488888 | 22 | + | 27260156 | A673 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.16500783712745415 | [243] | [349,357,357,243] | 4 | hSpCas9 | negative selection | 5743244 | 29483415 | 29483438 | 22 | + | 27260156 | A375 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.20186263045569194 | [448] | [662,788,670,344] | 3 | hSpCas9 | negative selection | 5800236 | 29485826 | 29485849 | 22 | + | 27260156 | A375 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.25487203402880915 | [303] | [487,321,515,360] | 4 | hSpCas9 | negative selection | 5864493 | 29483373 | 29483396 | 22 | + | 27260156 | A375 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.03048381286070756 | [726] | [684,1065,800,804] | 0 | hSpCas9 | negative selection | 5864494 | 29488865 | 29488888 | 22 | + | 27260156 | A375 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.6648316415211777 | [243] | [423,305,565,484] | 8 | hSpCas9 | negative selection | 5864495 | 29483415 | 29483438 | 22 | + | 27260156 | COLO741 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.001079293362299824 | [448] | [705,568,462] | 0 | hSpCas9 | negative selection | 5921487 | 29485826 | 29485849 | 22 | + | 27260156 | COLO741 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.4357837324039311 | [303] | [247,355,255] | -7 | hSpCas9 | negative selection | 5985744 | 29483373 | 29483396 | 22 | + | 27260156 | COLO741 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | 0.032670184923109025 | [726] | [727,928,1156] | 0 | hSpCas9 | negative selection | 5985745 | 29488865 | 29488888 | 22 | + | 27260156 | COLO741 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | -0.09008591364706842 | [243] | [365,307,215] | -2 | hSpCas9 | negative selection | 5985746 | 29483415 | 29483438 | 22 | + | 27260156 | CAL120 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.006393733010249633 | [448] | [515,506,637] | 0 | hSpCas9 | negative selection | 6042738 | 29485826 | 29485849 | 22 | + | 27260156 | CAL120 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.4680113579394458 | [303] | [250,181,381] | -6 | hSpCas9 | negative selection | 6106995 | 29483373 | 29483396 | 22 | + | 27260156 | CAL120 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.4182694549905326 | [726] | [756,624,660] | -6 | hSpCas9 | negative selection | 6106996 | 29488865 | 29488888 | 22 | + | 27260156 | CAL120 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.9772957365399658 | [243] | [391,876,494] | 9 | hSpCas9 | negative selection | 6106997 | 29483415 | 29483438 | 22 | + | 27260156 | CADOES1 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.03185889864581824 | [448] | [363,612,362,289] | 0 | hSpCas9 | negative selection | 6163989 | 29485826 | 29485849 | 22 | + | 27260156 | CADOES1 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.21769836083307414 | [303] | [321,193,193,262] | -4 | hSpCas9 | negative selection | 6228246 | 29483373 | 29483396 | 22 | + | 27260156 | CADOES1 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.4441864655588932 | [726] | [456,473,557,498] | -7 | hSpCas9 | negative selection | 6228247 | 29488865 | 29488888 | 22 | + | 27260156 | CADOES1 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.430909285241577 | [243] | [230,297,257,441] | 7 | hSpCas9 | negative selection | 6228248 | 29483415 | 29483438 | 22 | + | 27260156 | EWS502 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.202748142565592 | [448] | [314,494,423,426] | -4 | hSpCas9 | negative selection | 6285240 | 29485826 | 29485849 | 22 | + | 27260156 | EWS502 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.04827279151571018 | [303] | [246,313,357,429] | 0 | hSpCas9 | negative selection | 6349497 | 29483373 | 29483396 | 22 | + | 27260156 | EWS502 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | 0.036253336977420725 | [726] | [864,707,634,950] | 0 | hSpCas9 | negative selection | 6349498 | 29488865 | 29488888 | 22 | + | 27260156 | EWS502 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.22582715984374735 | [243] | [385,259,323,223] | 4 | hSpCas9 | negative selection | 6349499 | 29483415 | 29483438 | 22 | + | 27260156 | EW8 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.1306930302368702 | [448] | [322,334,298,375] | -2 | hSpCas9 | negative selection | 6406491 | 29485826 | 29485849 | 22 | + | 27260156 | EW8 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.19695364595240872 | [303] | [289,208,181,191] | -4 | hSpCas9 | negative selection | 6470748 | 29483373 | 29483396 | 22 | + | 27260156 | EW8 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | 0.049143121699253056 | [726] | [735,617,446,676] | 0 | hSpCas9 | negative selection | 6470749 | 29488865 | 29488888 | 22 | + | 27260156 | EW8 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.11566223974083312 | [243] | [196,262,188,209] | 2 | hSpCas9 | negative selection | 6470750 | 29483415 | 29483438 | 22 | + | 27260156 | CORL105 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.06426746330929851 | [448] | [608,489,559,543] | 1 | hSpCas9 | negative selection | 6527742 | 29485826 | 29485849 | 22 | + | 27260156 | CORL105 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.048234167633463 | [303] | [379,266,342,388] | -1 | hSpCas9 | negative selection | 6591999 | 29483373 | 29483396 | 22 | + | 27260156 | CORL105 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | 0.054213222518852855 | [726] | [945,1009,715,835] | 1 | hSpCas9 | negative selection | 6592000 | 29488865 | 29488888 | 22 | + | 27260156 | CORL105 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.25266510130914543 | [243] | [453,342,280,277] | 5 | hSpCas9 | negative selection | 6592001 | 29483415 | 29483438 | 22 | + | 27260156 | HS294T | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.705087917755562 | [448] | [225,244,338,336] | 8 | hSpCas9 | negative selection | 6648993 | 29485826 | 29485849 | 22 | + | 27260156 | HS294T | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.19072729833389124 | [303] | [103,102,98,105] | -3 | hSpCas9 | negative selection | 6713250 | 29483373 | 29483396 | 22 | + | 27260156 | HS294T | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | 0.11002098426048224 | [726] | [188,275,308,479] | 1 | hSpCas9 | negative selection | 6713251 | 29488865 | 29488888 | 22 | + | 27260156 | HS294T | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.1597376246690485 | [243] | [122,102,100,89] | 2 | hSpCas9 | negative selection | 6713252 | 29483415 | 29483438 | 22 | + | 27260156 | HCC44 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.10552932218205614 | [448] | [600,400,761,481] | 1 | hSpCas9 | negative selection | 6770244 | 29485826 | 29485849 | 22 | + | 27260156 | HCC44 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.09665367913776013 | [303] | [393,308,267,311] | -2 | hSpCas9 | negative selection | 6834501 | 29483373 | 29483396 | 22 | + | 27260156 | HCC44 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.32613856283535236 | [726] | [548,550,999,584] | -5 | hSpCas9 | negative selection | 6834502 | 29488865 | 29488888 | 22 | + | 27260156 | HCC44 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.09910645779475369 | [243] | [328,325,421,128] | 1 | hSpCas9 | negative selection | 6834503 | 29483415 | 29483438 | 22 | + | 27260156 | G402 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.08739734178252762 | [448] | [782,286,627,393] | -1 | hSpCas9 | negative selection | 6891495 | 29485826 | 29485849 | 22 | + | 27260156 | G402 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.1560602190867072 | [303] | [249,288,268,793] | 2 | hSpCas9 | negative selection | 6955752 | 29483373 | 29483396 | 22 | + | 27260156 | G402 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.5720430511739828 | [726] | [718,741,487,467] | -6 | hSpCas9 | negative selection | 6955753 | 29488865 | 29488888 | 22 | + | 27260156 | G402 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.564575679469443 | [243] | [465,441,342,508] | 7 | hSpCas9 | negative selection | 6955754 | 29483415 | 29483438 | 22 | + | 27260156 | L33 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.11344418111521357 | [448] | [433,206,222,647] | 2 | hSpCas9 | negative selection | 7012746 | 29485826 | 29485849 | 22 | + | 27260156 | L33 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.18599219378598708 | [303] | [284,91,129,350] | -4 | hSpCas9 | negative selection | 7077003 | 29483373 | 29483396 | 22 | + | 27260156 | L33 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | 0.06388352427312838 | [726] | [562,396,530,668] | 1 | hSpCas9 | negative selection | 7077004 | 29488865 | 29488888 | 22 | + | 27260156 | L33 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.12301806093751722 | [243] | [261,72,191,316] | 2 | hSpCas9 | negative selection | 7077005 | 29483415 | 29483438 | 22 | + | 27260156 | K562 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.4175565721094565 | [448] | [413,931,411,395] | 5 | hSpCas9 | negative selection | 7133997 | 29485826 | 29485849 | 22 | + | 27260156 | K562 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.26764803528125874 | [303] | [312,296,489,208] | 3 | hSpCas9 | negative selection | 7198254 | 29483373 | 29483396 | 22 | + | 27260156 | K562 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.1394691367222411 | [726] | [687,929,315,448] | -2 | hSpCas9 | negative selection | 7198255 | 29488865 | 29488888 | 22 | + | 27260156 | K562 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.5683961785671745 | [243] | [459,329,307,209] | 7 | hSpCas9 | negative selection | 7198256 | 29483415 | 29483438 | 22 | + | 27260156 | HT29 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.02309489112174276 | [448] | [573,667,530,463] | 0 | hSpCas9 | negative selection | 7255248 | 29485826 | 29485849 | 22 | + | 27260156 | HT29 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.2007423181792285 | [303] | [363,455,312,182] | -4 | hSpCas9 | negative selection | 7319505 | 29483373 | 29483396 | 22 | + | 27260156 | HT29 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.3058733089506821 | [726] | [686,965,677,561] | -5 | hSpCas9 | negative selection | 7319506 | 29488865 | 29488888 | 22 | + | 27260156 | HT29 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.26304591154752544 | [243] | [426,457,280,278] | 5 | hSpCas9 | negative selection | 7319507 | 29483415 | 29483438 | 22 | + | 27260156 | MHHES1 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.0512858869345781 | [448] | [593,493,497,506] | 1 | hSpCas9 | negative selection | 7376499 | 29485826 | 29485849 | 22 | + | 27260156 | MHHES1 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.07466872558944426 | [303] | [383,364,459,139] | -1 | hSpCas9 | negative selection | 7440756 | 29483373 | 29483396 | 22 | + | 27260156 | MHHES1 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.14438035516517067 | [726] | [852,870,626,643] | -3 | hSpCas9 | negative selection | 7440757 | 29488865 | 29488888 | 22 | + | 27260156 | MHHES1 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | -0.19883602644068143 | [243] | [382,303,170,140] | -4 | hSpCas9 | negative selection | 7440758 | 29483415 | 29483438 | 22 | + | 27260156 | MEWO | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.10487166935996198 | [448] | [523,475,368] | 2 | hSpCas9 | negative selection | 7497750 | 29485826 | 29485849 | 22 | + | 27260156 | MEWO | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.4796318199313767 | [303] | [229,183,202] | -8 | hSpCas9 | negative selection | 7562007 | 29483373 | 29483396 | 22 | + | 27260156 | MEWO | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.0037821329491694033 | [726] | [694,716,625] | 0 | hSpCas9 | negative selection | 7562008 | 29488865 | 29488888 | 22 | + | 27260156 | MEWO | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.0683222892628712 | [243] | [208,261,240] | 1 | hSpCas9 | negative selection | 7562009 | 29483415 | 29483438 | 22 | + | 27260156 | LNCAPCLONEFGC | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.39884060198565974 | [448] | [636,525,607,382] | 6 | hSpCas9 | negative selection | 7619001 | 29485826 | 29485849 | 22 | + | 27260156 | LNCAPCLONEFGC | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.26094024034291863 | [303] | [337,311,432,252] | 4 | hSpCas9 | negative selection | 7683258 | 29483373 | 29483396 | 22 | + | 27260156 | LNCAPCLONEFGC | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.12625216739993006 | [726] | [578,647,605,577] | -2 | hSpCas9 | negative selection | 7683259 | 29488865 | 29488888 | 22 | + | 27260156 | LNCAPCLONEFGC | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.11526101757317964 | [243] | [199,192,398,192] | 1 | hSpCas9 | negative selection | 7683260 | 29483415 | 29483438 | 22 | + | 27260156 | PANC0327 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.017283090768267458 | [448] | [542,331,312,446] | 0 | hSpCas9 | negative selection | 7740252 | 29485826 | 29485849 | 22 | + | 27260156 | PANC0327 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.018343056647932676 | [303] | [208,340,302,226] | 0 | hSpCas9 | negative selection | 7804509 | 29483373 | 29483396 | 22 | + | 27260156 | PANC0327 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.07468021818599768 | [726] | [1008,419,531,548] | -1 | hSpCas9 | negative selection | 7804510 | 29488865 | 29488888 | 22 | + | 27260156 | PANC0327 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.8570433980337238 | [243] | [503,256,441,393] | 9 | hSpCas9 | negative selection | 7804511 | 29483415 | 29483438 | 22 | + | 27260156 | NCIH2009 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.017177139725322907 | [448] | [741,833,344] | 0 | hSpCas9 | negative selection | 7861503 | 29485826 | 29485849 | 22 | + | 27260156 | NCIH2009 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.09345466332305452 | [303] | [433,503,415] | 1 | hSpCas9 | negative selection | 7925760 | 29483373 | 29483396 | 22 | + | 27260156 | NCIH2009 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.21599578416422716 | [726] | [1041,990,619] | -3 | hSpCas9 | negative selection | 7925761 | 29488865 | 29488888 | 22 | + | 27260156 | NCIH2009 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | -0.008821125391869855 | [243] | [506,291,250] | 0 | hSpCas9 | negative selection | 7925762 | 29483415 | 29483438 | 22 | + | 27260156 | NCIH1373 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.14067892480290983 | [448] | [715,441,389,188] | 1 | hSpCas9 | negative selection | 7982754 | 29485826 | 29485849 | 22 | + | 27260156 | NCIH1373 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.033878310375135 | [303] | [240,606,234,68] | 0 | hSpCas9 | negative selection | 8047011 | 29483373 | 29483396 | 22 | + | 27260156 | NCIH1373 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.6563859426413945 | [726] | [472,355,535,189] | -6 | hSpCas9 | negative selection | 8047012 | 29488865 | 29488888 | 22 | + | 27260156 | NCIH1373 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.27774427549695135 | [243] | [683,140,259,82] | 2 | hSpCas9 | negative selection | 8047013 | 29483415 | 29483438 | 22 | + | 27260156 | PATU8902 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.5838833252009517 | [448] | [829,998,1195,611] | 6 | hSpCas9 | negative selection | 8104005 | 29485826 | 29485849 | 22 | + | 27260156 | PATU8902 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.9602631572006068 | [303] | [240,109,145,412] | -7 | hSpCas9 | negative selection | 8168262 | 29483373 | 29483396 | 22 | + | 27260156 | PATU8902 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.8391757495796948 | [726] | [934,264,555,490] | -7 | hSpCas9 | negative selection | 8168263 | 29488865 | 29488888 | 22 | + | 27260156 | PATU8902 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.48225968501286276 | [243] | [518,539,314,573] | 5 | hSpCas9 | negative selection | 8168264 | 29483415 | 29483438 | 22 | + | 27260156 | PANC1 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.3126091943580045 | [448] | [398,304,363,186] | -5 | hSpCas9 | negative selection | 8225256 | 29485826 | 29485849 | 22 | + | 27260156 | PANC1 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.06547251680687693 | [303] | [297,283,238,188] | -1 | hSpCas9 | negative selection | 8289513 | 29483373 | 29483396 | 22 | + | 27260156 | PANC1 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.6441327456048963 | [726] | [307,511,379,413] | -7 | hSpCas9 | negative selection | 8289514 | 29488865 | 29488888 | 22 | + | 27260156 | PANC1 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.0005467267714917012 | [243] | [171,254,226,193] | 0 | hSpCas9 | negative selection | 8289515 | 29483415 | 29483438 | 22 | + | 27260156 | PANC0813 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.07471055387946747 | [448] | [567,512,530,606] | 1 | hSpCas9 | negative selection | 8346507 | 29485826 | 29485849 | 22 | + | 27260156 | PANC0813 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | 0.10070931543762873 | [303] | [347,322,572,289] | 1 | hSpCas9 | negative selection | 8410764 | 29483373 | 29483396 | 22 | + | 27260156 | PANC0813 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.18498039515224918 | [726] | [702,657,787,844] | -3 | hSpCas9 | negative selection | 8410765 | 29488865 | 29488888 | 22 | + | 27260156 | PANC0813 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.6361510299542872 | [243] | [297,539,491,437] | 8 | hSpCas9 | negative selection | 8410766 | 29483415 | 29483438 | 22 | + | 27260156 | RDES | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.07627455747985581 | [448] | [459,398,519,596] | -1 | hSpCas9 | negative selection | 8467758 | 29485826 | 29485849 | 22 | + | 27260156 | RDES | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.1675982515865987 | [303] | [252,293,357,352] | -3 | hSpCas9 | negative selection | 8532015 | 29483373 | 29483396 | 22 | + | 27260156 | RDES | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.41995377373745557 | [726] | [566,625,743,546] | -6 | hSpCas9 | negative selection | 8532016 | 29488865 | 29488888 | 22 | + | 27260156 | RDES | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.5857855721050234 | [243] | [319,366,438,601] | 8 | hSpCas9 | negative selection | 8532017 | 29483415 | 29483438 | 22 | + | 27260156 | PC3 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.07691014733020171 | [448] | [373,350,618,397] | -2 | hSpCas9 | negative selection | 8589009 | 29485826 | 29485849 | 22 | + | 27260156 | PC3 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.21557474766357332 | [303] | [203,158,361,362] | -5 | hSpCas9 | negative selection | 8653266 | 29483373 | 29483396 | 22 | + | 27260156 | PC3 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | 0.08171656729449017 | [726] | [654,632,1120,753] | 1 | hSpCas9 | negative selection | 8653267 | 29488865 | 29488888 | 22 | + | 27260156 | PC3 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.540171036243125 | [243] | [154,357,596,465] | 9 | hSpCas9 | negative selection | 8653268 | 29483415 | 29483438 | 22 | + | 27260156 | PATU8988T | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.010395377815590162 | [448] | [460,442,493,315] | 0 | hSpCas9 | negative selection | 8710260 | 29485826 | 29485849 | 22 | + | 27260156 | PATU8988T | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.0636501401024252 | [303] | [436,212,228,235] | -1 | hSpCas9 | negative selection | 8774517 | 29483373 | 29483396 | 22 | + | 27260156 | PATU8988T | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.006527787621654513 | [726] | [634,678,879,589] | 0 | hSpCas9 | negative selection | 8774518 | 29488865 | 29488888 | 22 | + | 27260156 | PATU8988T | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.3887698526223884 | [243] | [265,136,317,513] | 6 | hSpCas9 | negative selection | 8774519 | 29483415 | 29483438 | 22 | + | 27260156 | T47D | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.109717158046756 | [448] | [530,537,678,507] | 2 | hSpCas9 | negative selection | 8831511 | 29485826 | 29485849 | 22 | + | 27260156 | T47D | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.07316827687130356 | [303] | [306,402,318,310] | -2 | hSpCas9 | negative selection | 8895768 | 29483373 | 29483396 | 22 | + | 27260156 | T47D | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.2821229871109538 | [726] | [677,684,609,818] | -6 | hSpCas9 | negative selection | 8895769 | 29488865 | 29488888 | 22 | + | 27260156 | T47D | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.26693890462125003 | [243] | [289,310,388,380] | 5 | hSpCas9 | negative selection | 8895770 | 29483415 | 29483438 | 22 | + | 27260156 | SU8686 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.08819868736240152 | [448] | [445,390,456,634] | 1 | hSpCas9 | negative selection | 8952762 | 29485826 | 29485849 | 22 | + | 27260156 | SU8686 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.050350230438361954 | [303] | [293,259,287,329] | -1 | hSpCas9 | negative selection | 9017019 | 29483373 | 29483396 | 22 | + | 27260156 | SU8686 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.04433923529119799 | [726] | [536,663,694,959] | -1 | hSpCas9 | negative selection | 9017020 | 29488865 | 29488888 | 22 | + | 27260156 | SU8686 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | -0.24358757058400804 | [243] | [139,216,168,311] | -4 | hSpCas9 | negative selection | 9017021 | 29483415 | 29483438 | 22 | + | 27260156 | SKES1 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.07886697687062219 | [448] | [638,414,392,458] | 1 | hSpCas9 | negative selection | 9074013 | 29485826 | 29485849 | 22 | + | 27260156 | SKES1 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.12012445636430502 | [303] | [279,259,293,276] | -3 | hSpCas9 | negative selection | 9138270 | 29483373 | 29483396 | 22 | + | 27260156 | SKES1 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.32293161495293904 | [726] | [615,655,627,442] | -6 | hSpCas9 | negative selection | 9138271 | 29488865 | 29488888 | 22 | + | 27260156 | SKES1 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.4762577963205231 | [243] | [416,480,202,285] | 8 | hSpCas9 | negative selection | 9138272 | 29483415 | 29483438 | 22 | + | 27260156 | TOV112D | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.2051504398623307 | [448] | [401,566,344,292] | -4 | hSpCas9 | negative selection | 9195264 | 29485826 | 29485849 | 22 | + | 27260156 | TOV112D | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.3856338461063198 | [303] | [232,413,191,139] | -6 | hSpCas9 | negative selection | 9259521 | 29483373 | 29483396 | 22 | + | 27260156 | TOV112D | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.33727597491004874 | [726] | [648,628,596,451] | -6 | hSpCas9 | negative selection | 9259522 | 29488865 | 29488888 | 22 | + | 27260156 | TOV112D | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.24002061868376723 | [243] | [276,382,291,225] | 4 | hSpCas9 | negative selection | 9259523 | 29483415 | 29483438 | 22 | + | 27260156 | TC71 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.11490658121040526 | [448] | [358,595,309,523] | -3 | hSpCas9 | negative selection | 9316515 | 29485826 | 29485849 | 22 | + | 27260156 | TC71 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.33351314327161163 | [303] | [232,266,289,242] | -7 | hSpCas9 | negative selection | 9380772 | 29483373 | 29483396 | 22 | + | 27260156 | TC71 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.005065548813007914 | [726] | [780,754,738,835] | 0 | hSpCas9 | negative selection | 9380773 | 29488865 | 29488888 | 22 | + | 27260156 | TC71 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.3204521849870242 | [243] | [427,301,335,231] | 7 | hSpCas9 | negative selection | 9380774 | 29483415 | 29483438 | 22 | + | 27260156 | TC32 | viability | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | -0.027547923820194054 | [448] | [422,344,460,434] | 0 | hSpCas9 | negative selection | 9437766 | 29485826 | 29485849 | 22 | + | 27260156 | TC32 | viability | ATATAGAGATAGCCGCTTACAGG | NEFH | ENSG00000100285 | -0.1341716022982371 | [303] | [252,210,337,255] | -2 | hSpCas9 | negative selection | 9502023 | 29483373 | 29483396 | 22 | + | 27260156 | TC32 | viability | AGTGAGGCTGGACCGACTGTCGG | NEFH | ENSG00000100285 | -0.5248537153944008 | [726] | [513,170,757,597] | -7 | hSpCas9 | negative selection | 9502024 | 29488865 | 29488888 | 22 | + | 27260156 | TC32 | viability | GAAGAGTGTCGGATTGGCTTTGG | NEFH | ENSG00000100285 | 0.6470676243238491 | [243] | [367,233,487,395] | 9 | hSpCas9 | negative selection | 9502025 | 29483415 | 29483438 | 22 | + | 27869803 | HPAFII | viability after 27 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.6336874092321687 | [182] | [193,111,NaN] | 5 | hSpCas9 | negative selection | 9580314 | 29483418 | 29483441 | 22 | + | 27869803 | HPAFII | viability after 27 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.4352149463763235 | [71] | [60,42,NaN] | 3 | hSpCas9 | negative selection | 9580315 | 29483415 | 29483438 | 22 | + | 27869803 | HPAFII | viability after 15 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.48826839614292467 | [182] | [331,240,NaN] | 5 | hSpCas9 | negative selection | 9662763 | 29483418 | 29483441 | 22 | + | 27869803 | HPAFII | viability after 15 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.24555637811468456 | [71] | [145,57,NaN] | 3 | hSpCas9 | negative selection | 9662764 | 29483415 | 29483438 | 22 | + | 27869803 | ASPC1 | viability after 36 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.11627108056072721 | [441] | [150,253,107] | 1 | hSpCas9 | negative selection | 9745212 | 29483418 | 29483441 | 22 | + | 27869803 | ASPC1 | viability after 36 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.43692131057025874 | [220] | [151,53,109] | 4 | hSpCas9 | negative selection | 9745213 | 29483415 | 29483438 | 22 | + | 27869803 | PATU8988S | viability after 35 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.7513488151451688 | [406] | [247,303,NaN] | 7 | hSpCas9 | negative selection | 9827661 | 29483418 | 29483441 | 22 | + | 27869803 | PATU8988S | viability after 35 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.008650632623878884 | [115] | [46,46,NaN] | 0 | hSpCas9 | negative selection | 9827662 | 29483415 | 29483438 | 22 | + | 27869803 | PATU8988S | viability after 31 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.6314048286851827 | [406] | [235,270,NaN] | 7 | hSpCas9 | negative selection | 9910110 | 29483418 | 29483441 | 22 | + | 27869803 | PATU8988S | viability after 31 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 0.1364786998668115 | [115] | [67,28,NaN] | 1 | hSpCas9 | negative selection | 9910111 | 29483415 | 29483438 | 22 | + | 27869803 | HPAFII | viability after 35 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.9475898735413867 | [182] | [236,112,NaN] | 6 | hSpCas9 | negative selection | 9992559 | 29483418 | 29483441 | 22 | + | 27869803 | HPAFII | viability after 35 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 1.117819803548755 | [71] | [48,112,NaN] | 7 | hSpCas9 | negative selection | 9992560 | 29483415 | 29483438 | 22 | + | 27869803 | HPAFII | viability after 31 days | AGACGCTATGCGCTCAGCGCAGG | NEFH | ENSG00000100285 | 0.8315681123717973 | [182] | [199,163,NaN] | 6 | hSpCas9 | negative selection | 10075008 | 29483418 | 29483441 | 22 | + | 27869803 | HPAFII | viability after 31 days | CGCTATGCGCTCAGCGCAGGAGG | NEFH | ENSG00000100285 | 1.1232290797151925 | [71] | [54,123,NaN] | 8 | hSpCas9 | negative selection | 10075009 | 29485752 | 29485775 | 22 | + | 28162770 | P31FUJ | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -0.5827446754713372 | [129] | [101] | -5 | hSpCas9 | negative selection | 10199199 | 29485752 | 29485775 | 22 | + | 28162770 | TF1 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | NaN | [NaN] | [164] | 1 | hSpCas9 | negative selection | 10368565 | 29485752 | 29485775 | 22 | + | 28162770 | SKM1 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -1.4069641987431618 | [41] | [27] | -7 | hSpCas9 | negative selection | 10537931 | 29485752 | 29485775 | 22 | + | 28162770 | SKM1 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -1.4069641987431618 | [41] | [27] | -7 | hSpCas9 | negative selection | 10707297 | 29485752 | 29485775 | 22 | + | 28162770 | PL21 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | 0.5498856535164448 | [112] | [71] | 5 | hSpCas9 | negative selection | 10876663 | 29485752 | 29485775 | 22 | + | 28162770 | P31FUJ | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -0.5827446754713372 | [129] | [101] | -5 | hSpCas9 | negative selection | 11046029 | 29485752 | 29485775 | 22 | + | 28162770 | OCIAML5 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -1.543944275501665 | [104] | [64] | -7 | hSpCas9 | negative selection | 11215395 | 29485752 | 29485775 | 22 | + | 28162770 | EOL1 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -0.25720266526856755 | [244] | [107] | -2 | hSpCas9 | negative selection | 11384761 | 29485752 | 29485775 | 22 | + | 28162770 | MOLM13 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | 0.3362924987613659 | [194] | [177] | 2 | hSpCas9 | negative selection | 11554127 | 29485752 | 29485775 | 22 | + | 28162770 | HEL | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -0.14286153741672575 | [180] | [104] | -1 | hSpCas9 | negative selection | 11723493 | 29485752 | 29485775 | 22 | + | 28162770 | MV411 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -0.2920819791772139 | [124] | [85] | -2 | hSpCas9 | negative selection | 11892859 | 29485752 | 29485775 | 22 | + | 28162770 | MONOMAC1 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -0.28449968830989303 | [101] | [95] | -3 | hSpCas9 | negative selection | 12062225 | 29485752 | 29485775 | 22 | + | 28162770 | OCIAML2 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | -0.004311821019624129 | [18] | [104] | 0 | hSpCas9 | negative selection | 12231591 | 29485752 | 29485775 | 22 | + | 28162770 | OCIAML3 | viability | GAGGAACACCAAGTGGGAGATGG | NEFH | ENSG00000100285 | 0.8053992072409166 | [28] | [152] | 7 | hSpCas9 | negative selection | 12400957 |