| 24915682 | 24915705 | 8 | - | 26472758 | Jiyoye | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | 1.450244103397759 | [32] | [67] | 8 | hSpCas9 | negative selection | 107590 | 24918285 | 24918308 | 8 | + | 26472758 | Jiyoye | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -3.228413192285251 | [173] | [13] | -9 | hSpCas9 | negative selection | 107591 | 24917157 | 24917180 | 8 | + | 26472758 | Jiyoye | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 5.214530303563477 | [0] | [27] | 9 | hSpCas9 | negative selection | 107592 | 24917241 | 24917264 | 8 | + | 26472758 | Jiyoye | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | -1.5449960934035114 | [177] | [45] | -7 | hSpCas9 | negative selection | 107593 | 24917268 | 24917291 | 8 | + | 26472758 | Jiyoye | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.4590083149821973 | [462] | [253] | -3 | hSpCas9 | negative selection | 107594 | 24917652 | 24917675 | 8 | + | 26472758 | Jiyoye | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -2.735782572336169 | [52] | [5] | -9 | hSpCas9 | negative selection | 107595 | 24917985 | 24918008 | 8 | + | 26472758 | Jiyoye | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 4.577100382948185 | [0] | [17] | 9 | hSpCas9 | negative selection | 107596 | 24918156 | 24918179 | 8 | + | 26472758 | Jiyoye | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -1.8216433089900077 | [74] | [15] | -8 | hSpCas9 | negative selection | 107597 | 24918169 | 24918192 | 8 | + | 26472758 | Jiyoye | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | 0.40717538150587274 | [0] | [0] | 3 | hSpCas9 | negative selection | 107598 | 24918267 | 24918290 | 8 | + | 26472758 | Jiyoye | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -5.762749619936439 | [71] | [0] | -9 | hSpCas9 | negative selection | 107599 | 24915682 | 24915705 | 8 | - | 26472758 | KBM7 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | -0.6286265062591565 | [390,309] | [136,77] | -5 | hSpCas9 | negative selection | 298708 | 24918285 | 24918308 | 8 | + | 26472758 | KBM7 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -2.6098242557193485 | [639,679] | [74,29] | -9 | hSpCas9 | negative selection | 298709 | 24917157 | 24917180 | 8 | + | 26472758 | KBM7 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | -0.018866912445192785 | [85,102] | [44,43] | 0 | hSpCas9 | negative selection | 298710 | 24917241 | 24917264 | 8 | + | 26472758 | KBM7 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.5405408676539355 | [235,168] | [177,99] | 6 | hSpCas9 | negative selection | 298711 | 24917268 | 24917291 | 8 | + | 26472758 | KBM7 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.21249907911656307 | [1149,836] | [597,478] | 2 | hSpCas9 | negative selection | 298712 | 24917652 | 24917675 | 8 | + | 26472758 | KBM7 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -1.256494362557293 | [119,138] | [38,13] | -7 | hSpCas9 | negative selection | 298713 | 24917985 | 24918008 | 8 | + | 26472758 | KBM7 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 0.5158862325825657 | [128,126] | [40,126] | 5 | hSpCas9 | negative selection | 298714 | 24918156 | 24918179 | 8 | + | 26472758 | KBM7 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -1.8834917635217743 | [168,229] | [26,24] | -8 | hSpCas9 | negative selection | 298715 | 24918169 | 24918192 | 8 | + | 26472758 | KBM7 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | -0.7319440068324328 | [41,8] | [10,2] | -6 | hSpCas9 | negative selection | 298716 | 24918267 | 24918290 | 8 | + | 26472758 | KBM7 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -6.646302022868453 | [173,242] | [0,0] | -9 | hSpCas9 | negative selection | 298717 | 24915682 | 24915705 | 8 | - | 26472758 | Raji | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | 1.552794683695962 | [140] | [95] | 9 | hSpCas9 | negative selection | 489826 | 24918285 | 24918308 | 8 | + | 26472758 | Raji | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -2.6608007894033268 | [217] | [7] | -9 | hSpCas9 | negative selection | 489827 | 24917157 | 24917180 | 8 | + | 26472758 | Raji | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 0.4069438172325075 | [38] | [11] | 4 | hSpCas9 | negative selection | 489828 | 24917241 | 24917264 | 8 | + | 26472758 | Raji | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 1.0324214776923775 | [157] | [74] | 8 | hSpCas9 | negative selection | 489829 | 24917268 | 24917291 | 8 | + | 26472758 | Raji | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 1.0373198355257665 | [442] | [210] | 8 | hSpCas9 | negative selection | 489830 | 24917652 | 24917675 | 8 | + | 26472758 | Raji | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -1.4574010834099265 | [70] | [5] | -7 | hSpCas9 | negative selection | 489831 | 24917985 | 24918008 | 8 | + | 26472758 | Raji | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 0.22696515112627225 | [80] | [21] | 2 | hSpCas9 | negative selection | 489832 | 24918156 | 24918179 | 8 | + | 26472758 | Raji | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -0.799507060234919 | [44] | [5] | -6 | hSpCas9 | negative selection | 489833 | 24918169 | 24918192 | 8 | + | 26472758 | Raji | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | 4.1073835353736 | [0] | [3] | 9 | hSpCas9 | negative selection | 489834 | 24918267 | 24918290 | 8 | + | 26472758 | Raji | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -1.1531440148496195 | [114] | [11] | -7 | hSpCas9 | negative selection | 489835 | 24915682 | 24915705 | 8 | - | 26472758 | K562 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | 0.7167523732766976 | [252] | [350] | 6 | hSpCas9 | negative selection | 680944 | 24918285 | 24918308 | 8 | + | 26472758 | K562 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -4.525235485205934 | [490] | [17] | -9 | hSpCas9 | negative selection | 680945 | 24917157 | 24917180 | 8 | + | 26472758 | K562 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 0.4195054342245381 | [61] | [69] | 3 | hSpCas9 | negative selection | 680946 | 24917241 | 24917264 | 8 | + | 26472758 | K562 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 1.1309926663320926 | [204] | [378] | 8 | hSpCas9 | negative selection | 680947 | 24917268 | 24917291 | 8 | + | 26472758 | K562 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.8098410419919582 | [891] | [1319] | 6 | hSpCas9 | negative selection | 680948 | 24917652 | 24917675 | 8 | + | 26472758 | K562 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -1.789528604256891 | [85] | [20] | -7 | hSpCas9 | negative selection | 680949 | 24917985 | 24918008 | 8 | + | 26472758 | K562 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | -2.1229523379820825 | [128] | [24] | -7 | hSpCas9 | negative selection | 680950 | 24918156 | 24918179 | 8 | + | 26472758 | K562 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -3.9388030963893232 | [217] | [11] | -9 | hSpCas9 | negative selection | 680951 | 24918169 | 24918192 | 8 | + | 26472758 | K562 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | 4.859128571781655 | [3] | [97] | 9 | hSpCas9 | negative selection | 680952 | 24918267 | 24918290 | 8 | + | 26472758 | K562 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -6.594785060430497 | [228] | [1] | -9 | hSpCas9 | negative selection | 680953 | 24915601 | 24915624 | 8 | + | 26627737 | DLD1 | viability | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.9970060894290934 | [493] | [365,288,273] | 8 | hSpCas9 | negative selection | 839153 | 24917268 | 24917291 | 8 | + | 26627737 | DLD1 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.11400993186621089 | [784] | [390,111,283] | 1 | hSpCas9 | negative selection | 839154 | 24915601 | 24915624 | 8 | + | 26627737 | GBM cells | viability after 5 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.5011168256956735 | [304] | [222,239] | 7 | hSpCas9 | negative selection | 921468 | 24917268 | 24917291 | 8 | + | 26627737 | GBM cells | viability after 5 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.28655481045497255 | [411] | [236,301] | 4 | hSpCas9 | negative selection | 921469 | 24915601 | 24915624 | 8 | + | 26627737 | GBM cells | viability after 13 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.6570998038261666 | [304] | [314,216] | 7 | hSpCas9 | negative selection | 1003783 | 24917268 | 24917291 | 8 | + | 26627737 | GBM cells | viability after 13 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.020147482019888585 | [411] | [204,232] | 0 | hSpCas9 | negative selection | 1003784 | 24915601 | 24915624 | 8 | + | 26627737 | GBM cells | viability after 21 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.19480568986971425 | [304] | [185,192] | 2 | hSpCas9 | negative selection | 1086098 | 24917268 | 24917291 | 8 | + | 26627737 | GBM cells | viability after 21 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.09385486776039209 | [411] | [215,203] | -1 | hSpCas9 | negative selection | 1086099 | 24915601 | 24915624 | 8 | + | 26627737 | RPE1 | viability after 9 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.6066287921909371 | [1047] | [606,360] | 4 | hSpCas9 | negative selection | 1168413 | 24917268 | 24917291 | 8 | + | 26627737 | RPE1 | viability after 9 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.296546806021839 | [1727] | [663,664] | 2 | hSpCas9 | negative selection | 1168414 | 24915601 | 24915624 | 8 | + | 26627737 | RPE1 | viability after 12 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.3460435567954915 | [1047] | [387,325] | 2 | hSpCas9 | negative selection | 1250728 | 24917268 | 24917291 | 8 | + | 26627737 | RPE1 | viability after 12 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.17291526749263886 | [1727] | [399,653] | 1 | hSpCas9 | negative selection | 1250729 | 24915601 | 24915624 | 8 | + | 26627737 | RPE1 | viability after 15 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.18645047732900766 | [1047] | [232,437] | 1 | hSpCas9 | negative selection | 1333043 | 24917268 | 24917291 | 8 | + | 26627737 | RPE1 | viability after 15 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.06519605522168481 | [1727] | [426,505] | 0 | hSpCas9 | negative selection | 1333044 | 24915601 | 24915624 | 8 | + | 26627737 | RPE1 | viability after 18 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.32840190087747656 | [1047] | [445,257] | 2 | hSpCas9 | negative selection | 1415358 | 24917268 | 24917291 | 8 | + | 26627737 | RPE1 | viability after 18 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.05352116773297633 | [1727] | [444,453] | 0 | hSpCas9 | negative selection | 1415359 | 24915601 | 24915624 | 8 | + | 26627737 | HeLa | viability after 8 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | -0.5831803940902145 | [699] | [172,222,206] | -5 | hSpCas9 | negative selection | 1497673 | 24917268 | 24917291 | 8 | + | 26627737 | HeLa | viability after 8 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.11195584179936846 | [736] | [437,336,288] | 1 | hSpCas9 | negative selection | 1497674 | 24915601 | 24915624 | 8 | + | 26627737 | HeLa | viability after 12 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | -0.6271692115254075 | [699] | [50,280,215] | -5 | hSpCas9 | negative selection | 1579988 | 24917268 | 24917291 | 8 | + | 26627737 | HeLa | viability after 12 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.445458190488246 | [736] | [241,256,168] | -4 | hSpCas9 | negative selection | 1579989 | 24915601 | 24915624 | 8 | + | 26627737 | HeLa | viability after 15 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | -0.3703524655423192 | [699] | [219,176,267] | -3 | hSpCas9 | negative selection | 1662303 | 24917268 | 24917291 | 8 | + | 26627737 | HeLa | viability after 15 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.4950416058057408 | [736] | [66,330,244] | -4 | hSpCas9 | negative selection | 1662304 | 24915601 | 24915624 | 8 | + | 26627737 | HeLa | viability after 18 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | -0.34918277407147097 | [699] | [155,143,267] | -3 | hSpCas9 | negative selection | 1744618 | 24917268 | 24917291 | 8 | + | 26627737 | HeLa | viability after 18 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.5055875779134098 | [736] | [49,263,244] | -4 | hSpCas9 | negative selection | 1744619 | 24915601 | 24915624 | 8 | + | 26627737 | HCT116 | viability after 6 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 1.4412833050202414 | [504] | [261,189] | 7 | hSpCas9 | negative selection | 1826933 | 24917268 | 24917291 | 8 | + | 26627737 | HCT116 | viability after 6 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.7098876667810108 | [833] | [285,174] | 4 | hSpCas9 | negative selection | 1826934 | 24915601 | 24915624 | 8 | + | 26627737 | HCT116 | viability after 8 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.3781611877147073 | [301] | [146,316,183] | 4 | hSpCas9 | negative selection | 1909248 | 24917268 | 24917291 | 8 | + | 26627737 | HCT116 | viability after 8 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.5780883576035937 | [425] | [258,467,322] | 6 | hSpCas9 | negative selection | 1909249 | 24915601 | 24915624 | 8 | + | 26627737 | HCT116 | viability after 9 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.7746849901402437 | [504] | [328,152] | 5 | hSpCas9 | negative selection | 1991563 | 24917268 | 24917291 | 8 | + | 26627737 | HCT116 | viability after 9 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.2520134012510941 | [833] | [186,326] | 2 | hSpCas9 | negative selection | 1991564 | 24915601 | 24915624 | 8 | + | 26627737 | HCT116 | viability after 12 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.5638977453439499 | [301] | [200,201,302] | 5 | hSpCas9 | negative selection | 2073878 | 24917268 | 24917291 | 8 | + | 26627737 | HCT116 | viability after 12 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.2830613617154393 | [425] | [213,381,228] | 3 | hSpCas9 | negative selection | 2073879 | 24915601 | 24915624 | 8 | + | 26627737 | HCT116 | viability after 15 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.5168248019253793 | [301] | [225,203,310] | 5 | hSpCas9 | negative selection | 2156193 | 24917268 | 24917291 | 8 | + | 26627737 | HCT116 | viability after 15 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.27867112223820356 | [425] | [275,330,280] | 2 | hSpCas9 | negative selection | 2156194 | 24915601 | 24915624 | 8 | + | 26627737 | HCT116 | viability after 18 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.9210061195730377 | [301] | [213,304,309] | 7 | hSpCas9 | negative selection | 2238508 | 24917268 | 24917291 | 8 | + | 26627737 | HCT116 | viability after 18 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.35021834749383773 | [425] | [162,359,257] | 3 | hSpCas9 | negative selection | 2238509 | 24914852 | 24914875 | 8 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCACGACCTCAGCAGCTACCAGG | NEFM | ENSG00000104722 | -1.3196893241999372 | [591,76] | [46,8] | -7 | dCas9-VP64 | positive selection | 2396700 | 24914770 | 24914793 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CGACTCTAGCTCGATGCTCTTGG | NEFM | ENSG00000104722 | 0.8384002404171145 | [75,99] | [10,59] | 3 | dCas9-VP64 | positive selection | 2396701 | 24914819 | 24914842 | 8 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCGGCAGCTCAGCGACATCGAGG | NEFM | ENSG00000104722 | 1.6739781864735956 | [32,168] | [62,80] | 6 | dCas9-VP64 | positive selection | 2396702 | 24914852 | 24914875 | 8 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCACGACCTCAGCAGCTACCAGG | NEFM | ENSG00000104722 | -0.806882003055017 | [164,124] | [18,33] | -7 | dCas9-VP64 | positive selection | 2491955 | 24914770 | 24914793 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CGACTCTAGCTCGATGCTCTTGG | NEFM | ENSG00000104722 | 0.08559552268025322 | [110,78] | [39,25] | 0 | dCas9-VP64 | positive selection | 2491956 | 24914819 | 24914842 | 8 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCGGCAGCTCAGCGACATCGAGG | NEFM | ENSG00000104722 | 1.8247349115016056 | [136,187] | [284,96] | 8 | dCas9-VP64 | positive selection | 2491957 | 24917224 | 24917247 | 8 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CATAGAGGAAACCAAAGTGGAGG | NEFM | ENSG00000104722 | -0.6587519799805127 | [2,2] | [1,0] | -7 | hSpCas9 | positive selection | 3005209 | 24915680 | 24915703 | 8 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGACCTCCTCAACGTCAAGATGG | NEFM | ENSG00000104722 | 0.1450452583281993 | [2,2] | [2,1] | 3 | hSpCas9 | positive selection | 3005210 | 24917242 | 24917265 | 8 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.15495730536550578 | [3,3] | [2,3] | 3 | hSpCas9 | positive selection | 3005211 | 24917053 | 24917076 | 8 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TCTCCTTAGAAAACTCCTGGAGG | NEFM | ENSG00000104722 | 0.1949255926411323 | [1,0] | [2,0] | 4 | hSpCas9 | positive selection | 3005212 | 24917224 | 24917247 | 8 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CATAGAGGAAACCAAAGTGGAGG | NEFM | ENSG00000104722 | 0.03802495396404981 | [2,2] | [3,1] | 0 | hSpCas9 | positive selection | 3073067 | 24915680 | 24915703 | 8 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGACCTCCTCAACGTCAAGATGG | NEFM | ENSG00000104722 | -0.31974453150353155 | [2,2] | [2,0] | -5 | hSpCas9 | positive selection | 3073068 | 24917242 | 24917265 | 8 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.8219809938899963 | [3,3] | [4,4] | 9 | hSpCas9 | positive selection | 3073069 | 24917053 | 24917076 | 8 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TCTCCTTAGAAAACTCCTGGAGG | NEFM | ENSG00000104722 | -0.2626817420815504 | [1,1] | [1,0] | -4 | hSpCas9 | positive selection | 3073070 | 24917279 | 24917302 | | - | 24336571 | A375 | resistance to PLX after 7 days | AACGGCCAATTCCTCTGTAATGG | NEFM | ENSG00000104722 | -0.2983875703685656 | [16,17] | [14,13] | -8 | hSpCas9 | positive selection | 3130270 | 24918564 | 24918587 | | + | 24336571 | A375 | resistance to PLX after 7 days | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.6317323053563607 | [11,13] | [26,13] | 9 | hSpCas9 | positive selection | 3130271 | 24915658 | 24915681 | | + | 24336571 | A375 | resistance to PLX after 7 days | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.07490960129831326 | [68,69] | [75,69] | 2 | hSpCas9 | positive selection | 3130272 | 24917279 | 24917302 | | - | 24336571 | A375 | resistance to PLX after 14 days | AACGGCCAATTCCTCTGTAATGG | NEFM | ENSG00000104722 | -0.24302736767397787 | [14,22] | [5,7] | -3 | hSpCas9 | positive selection | 3188063 | 24918564 | 24918587 | | + | 24336571 | A375 | resistance to PLX after 14 days | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | -0.44656447809600863 | [12,17] | [3,5] | -5 | hSpCas9 | positive selection | 3188064 | 24915658 | 24915681 | | + | 24336571 | A375 | resistance to PLX after 14 days | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.2737619069682533 | [65,70] | [38,37] | 2 | hSpCas9 | positive selection | 3188065 | 24917279 | 24917302 | | - | 24336571 | A375 | viability after 7 days | AACGGCCAATTCCTCTGTAATGG | NEFM | ENSG00000104722 | -0.28023648691540115 | [22] | [16,17] | -4 | hSpCas9 | negative selection | 3245856 | 24918564 | 24918587 | | + | 24336571 | A375 | viability after 7 days | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | -0.6312713919576923 | [20] | [11,13] | -7 | hSpCas9 | negative selection | 3245857 | 24915658 | 24915681 | | + | 24336571 | A375 | viability after 7 days | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.31852195037358744 | [58] | [68,69] | 5 | hSpCas9 | negative selection | 3245858 | 24917279 | 24917302 | | - | 24336571 | A375 | viability after 14 days | AACGGCCAATTCCTCTGTAATGG | NEFM | ENSG00000104722 | -0.19321737209490275 | [22] | [14,22] | -2 | hSpCas9 | negative selection | 3303649 | 24918564 | 24918587 | | + | 24336571 | A375 | viability after 14 days | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | -0.358418171237298 | [20] | [12,17] | -4 | hSpCas9 | negative selection | 3303650 | 24915658 | 24915681 | | + | 24336571 | A375 | viability after 14 days | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.30627731538219827 | [58] | [65,70] | 4 | hSpCas9 | negative selection | 3303651 | 24917196 | 24917219 | 8 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | -0.8616148612776724 | [277,277] | [0,0] | -6 | hSpCas9 | positive selection | 3381421 | 24915708 | 24915731 | 8 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | 1.449971289388231 | [55,55] | [0,0] | 6 | hSpCas9 | positive selection | 3381422 | 24918564 | 24918587 | 8 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.28004628794591846 | [125,125] | [0,0] | 1 | hSpCas9 | positive selection | 3381423 | 24917223 | 24917246 | 8 | + | 26780180 | HT29 | viability (Avana library 4 designs) | CATAGAGGAAACCAAAGTGGAGG | NEFM | ENSG00000104722 | 1.60470904550254 | [] | [] | 6 | hSpCas9 | negative selection | 3443043 | 24915679 | 24915702 | 8 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GGACCTCCTCAACGTCAAGATGG | NEFM | ENSG00000104722 | 1.00709571668668 | [] | [] | 4 | hSpCas9 | negative selection | 3443044 | 24917241 | 24917264 | 8 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 1.01762509750566 | [] | [] | 4 | hSpCas9 | negative selection | 3443045 | 24917052 | 24917075 | 8 | + | 26780180 | HT29 | viability (Avana library 4 designs) | TCTCCTTAGAAAACTCCTGGAGG | NEFM | ENSG00000104722 | -0.762224910954329 | [] | [] | -8 | hSpCas9 | negative selection | 3443046 | 24917241 | 24917264 | 8 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | -1.22431466774049 | [] | [] | -1 | hSpCas9 | negative selection | 3534541 | 24917052 | 24917075 | 8 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TCTCCTTAGAAAACTCCTGGAGG | NEFM | ENSG00000104722 | -0.627345445700303 | [] | [] | -1 | hSpCas9 | negative selection | 3534542 | 24915679 | 24915702 | 8 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGACCTCCTCAACGTCAAGATGG | NEFM | ENSG00000104722 | 4.11825281571689 | [] | [] | 6 | hSpCas9 | negative selection | 3534543 | 24917223 | 24917246 | 8 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CATAGAGGAAACCAAAGTGGAGG | NEFM | ENSG00000104722 | -0.610089655029968 | [] | [] | 0 | hSpCas9 | negative selection | 3534544 | 24917196 | 24917219 | 8 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 2.05800702144011 | [] | [] | 3 | hSpCas9 | negative selection | 3534545 | 24917418 | 24917441 | 8 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AGAAGAGGAAGGGGAAAAGGAGG | NEFM | ENSG00000104722 | -17.9514235116885 | [] | [] | -9 | hSpCas9 | negative selection | 3534546 | 24917241 | 24917264 | 8 | + | 26780180 | A375 | viability (Avana lentiGuide) | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | -5.96628560621133 | [] | [] | -8 | hSpCas9 | negative selection | 3643200 | 24917052 | 24917075 | 8 | + | 26780180 | A375 | viability (Avana lentiGuide) | TCTCCTTAGAAAACTCCTGGAGG | NEFM | ENSG00000104722 | 5.18921075904993 | [] | [] | 4 | hSpCas9 | negative selection | 3643201 | 24915679 | 24915702 | 8 | + | 26780180 | A375 | viability (Avana lentiGuide) | GGACCTCCTCAACGTCAAGATGG | NEFM | ENSG00000104722 | -0.86541743822978 | [] | [] | -1 | hSpCas9 | negative selection | 3643202 | 24917223 | 24917246 | 8 | + | 26780180 | A375 | viability (Avana lentiGuide) | CATAGAGGAAACCAAAGTGGAGG | NEFM | ENSG00000104722 | 13.8493435886346 | [] | [] | 7 | hSpCas9 | negative selection | 3643203 | 24917196 | 24917219 | 8 | + | 26780180 | A375 | viability (Avana lentiGuide) | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | -3.74660936925383 | [] | [] | -6 | hSpCas9 | negative selection | 3643204 | 24917418 | 24917441 | 8 | + | 26780180 | A375 | viability (Avana lentiGuide) | AGAAGAGGAAGGGGAAAAGGAGG | NEFM | ENSG00000104722 | 34.0568242595863 | [] | [] | 9 | hSpCas9 | negative selection | 3643205 | 24917241 | 24917264 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | -0.36538478869187924 | [4] | [4,2] | -5 | hSpCas9 | positive selection | 3751859 | 24917052 | 24917075 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TCTCCTTAGAAAACTCCTGGAGG | NEFM | ENSG00000104722 | -0.16305134601983884 | [0] | [0,0] | -3 | hSpCas9 | positive selection | 3751860 | 24915679 | 24915702 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGACCTCCTCAACGTCAAGATGG | NEFM | ENSG00000104722 | -0.17259148619254355 | [3] | [4,1] | -3 | hSpCas9 | positive selection | 3751861 | 24917223 | 24917246 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CATAGAGGAAACCAAAGTGGAGG | NEFM | ENSG00000104722 | 0.15443685256486386 | [4] | [4,5] | 4 | hSpCas9 | positive selection | 3751862 | 24917196 | 24917219 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.1244489272128545 | [6] | [6,6] | 3 | hSpCas9 | positive selection | 3751863 | 24917418 | 24917441 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AGAAGAGGAAGGGGAAAAGGAGG | NEFM | ENSG00000104722 | -1.9029087655424972 | [5] | [0,0] | -9 | hSpCas9 | positive selection | 3751864 | 24917241 | 24917264 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.1648923161189823 | [4] | [3,5] | 4 | hSpCas9 | positive selection | 3860466 | 24917052 | 24917075 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TCTCCTTAGAAAACTCCTGGAGG | NEFM | ENSG00000104722 | -1.4106030888104912 | [2] | [0,0] | -9 | hSpCas9 | positive selection | 3860467 | 24915679 | 24915702 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGACCTCCTCAACGTCAAGATGG | NEFM | ENSG00000104722 | 0.19739852628737153 | [2] | [4,1] | 5 | hSpCas9 | positive selection | 3860468 | 24917223 | 24917246 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CATAGAGGAAACCAAAGTGGAGG | NEFM | ENSG00000104722 | -0.2902307518556865 | [4] | [2,3] | -4 | hSpCas9 | positive selection | 3860469 | 24917196 | 24917219 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.349858983021911 | [6] | [7,6] | 9 | hSpCas9 | positive selection | 3860470 | 24917418 | 24917441 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AGAAGAGGAAGGGGAAAAGGAGG | NEFM | ENSG00000104722 | -1.5043447097382752 | [6] | [0,1] | -9 | hSpCas9 | positive selection | 3860471 | 24915708 | 24915731 | 8 | + | 26780180 | A375 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | 1.07938207028534 | [] | [] | 5 | hSpCas9 | negative selection | 3971793 | 24918564 | 24918587 | 8 | + | 26780180 | A375 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 1.09633839639748 | [] | [] | 5 | hSpCas9 | negative selection | 3971794 | 24917196 | 24917219 | 8 | + | 26780180 | A375 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 1.40821256307972 | [] | [] | 7 | hSpCas9 | negative selection | 3971795 | 24915658 | 24915681 | 8 | + | 26780180 | A375 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 1.46534380137693 | [] | [] | 8 | hSpCas9 | negative selection | 3971796 | 24915708 | 24915731 | 8 | + | 26780180 | HT29 | viability (GeCKOv2 library) | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | 1.69736494649492 | [] | [] | 8 | hSpCas9 | negative selection | 4079759 | 24918564 | 24918587 | 8 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 1.00788224908713 | [] | [] | 4 | hSpCas9 | negative selection | 4079760 | 24917196 | 24917219 | 8 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 1.40746665946277 | [] | [] | 7 | hSpCas9 | negative selection | 4079761 | 24915658 | 24915681 | 8 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 1.36901242288311 | [] | [] | 7 | hSpCas9 | negative selection | 4079762 | 24917279 | 24917302 | 8 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | AACGGCCAATTCCTCTGTAATGG | NEFM | ENSG00000104722 | -0.05443364554579572 | [4] | [2,2] | -1 | hSpCas9 | positive selection | 4154909 | 24918564 | 24918587 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | -0.36324681935431524 | [4] | [2,2] | -7 | hSpCas9 | positive selection | 4154910 | 24915658 | 24915681 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.28797960987846694 | [5] | [4,5] | 7 | hSpCas9 | positive selection | 4154911 | 24917279 | 24917302 | 8 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | AACGGCCAATTCCTCTGTAATGG | NEFM | ENSG00000104722 | 0.03498029370309097 | [4] | [1,2,4,0] | 0 | hSpCas9 | positive selection | 4218931 | 24918564 | 24918587 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 1.0333924235748873 | [4] | [4,0,4,3] | 7 | hSpCas9 | positive selection | 4218932 | 24915658 | 24915681 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 1.179974655933333 | [5] | [4,4,4,6] | 8 | hSpCas9 | positive selection | 4218933 | 24915658 | 24915681 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | -0.33746845448472895 | [2] | [2,0] | -6 | hSpCas9 | positive selection | 4285280 | 24917196 | 24917219 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | -0.34504284086577225 | [3] | [2,0] | -6 | hSpCas9 | positive selection | 4349537 | 24915708 | 24915731 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | 0.42676499857151445 | [2] | [2,2] | 8 | hSpCas9 | positive selection | 4349538 | 24918564 | 24918587 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.014691950564190911 | [2] | [3,1] | 0 | hSpCas9 | positive selection | 4349539 | 24917096 | 24917118 | 8 | + | 27760321 | OCIAML3 | viability | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | 0.2884123194990814 | [407,361] | [400,322] | 3 | hSpCas9 | negative selection | 4421843 | 24917140 | 24917162 | 8 | - | 27760321 | OCIAML3 | viability | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | -1.0902529693721643 | [56,52] | [14,26] | -7 | hSpCas9 | negative selection | 4421844 | 24917171 | 24917193 | 8 | - | 27760321 | OCIAML3 | viability | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | -1.0393897194293154 | [553,525] | [216,190] | -7 | hSpCas9 | negative selection | 4421845 | 24917197 | 24917219 | 8 | + | 27760321 | OCIAML3 | viability | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | -0.07920444449582065 | [431,336] | [227,353] | -1 | hSpCas9 | negative selection | 4421846 | 24917275 | 24917297 | 8 | + | 27760321 | OCIAML3 | viability | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | 0.498001770664669 | [262,195] | [262,235] | 6 | hSpCas9 | negative selection | 4421847 | 24917096 | 24917118 | 8 | + | 27760321 | OCIAML2 | viability | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | 0.6617621922153504 | [407,361] | [440,558] | 8 | hSpCas9 | negative selection | 4505306 | 24917140 | 24917162 | 8 | - | 27760321 | OCIAML2 | viability | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | 0.9832910934520958 | [56,52] | [68,112] | 9 | hSpCas9 | negative selection | 4505307 | 24917171 | 24917193 | 8 | - | 27760321 | OCIAML2 | viability | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | -1.1099776069661664 | [553,525] | [215,184] | -8 | hSpCas9 | negative selection | 4505308 | 24917197 | 24917219 | 8 | + | 27760321 | OCIAML2 | viability | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.30864044872162444 | [431,336] | [294,497] | 4 | hSpCas9 | negative selection | 4505309 | 24917275 | 24917297 | 8 | + | 27760321 | OCIAML2 | viability | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | 0.2144105221273508 | [262,195] | [156,287] | 3 | hSpCas9 | negative selection | 4505310 | 24917096 | 24917118 | 8 | + | 27760321 | MV411 | viability | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | -0.6982767882910786 | [407,361] | [67,288] | -5 | hSpCas9 | negative selection | 4588769 | 24917140 | 24917162 | 8 | - | 27760321 | MV411 | viability | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | 0.8889673643454317 | [56,52] | [105,8] | 6 | hSpCas9 | negative selection | 4588770 | 24917171 | 24917193 | 8 | - | 27760321 | MV411 | viability | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | 0.057297011953210075 | [553,525] | [144,710] | 0 | hSpCas9 | negative selection | 4588771 | 24917197 | 24917219 | 8 | + | 27760321 | MV411 | viability | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | -0.32344812236966247 | [431,336] | [178,234] | -2 | hSpCas9 | negative selection | 4588772 | 24917275 | 24917297 | 8 | + | 27760321 | MV411 | viability | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | -1.2301802332429772 | [262,195] | [57,72] | -7 | hSpCas9 | negative selection | 4588773 | 24917096 | 24917118 | 8 | + | 27760321 | HL60 | viability | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | 0.8979937286409367 | [407,361] | [538,633] | 8 | hSpCas9 | negative selection | 4672232 | 24917140 | 24917162 | 8 | - | 27760321 | HL60 | viability | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | 1.1454584655017555 | [56,52] | [46,154] | 9 | hSpCas9 | negative selection | 4672233 | 24917171 | 24917193 | 8 | - | 27760321 | HL60 | viability | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | 0.18318537295927018 | [553,525] | [597,398] | 2 | hSpCas9 | negative selection | 4672234 | 24917197 | 24917219 | 8 | + | 27760321 | HL60 | viability | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.5404192315092677 | [431,336] | [442,464] | 6 | hSpCas9 | negative selection | 4672235 | 24917275 | 24917297 | 8 | + | 27760321 | HL60 | viability | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | -0.04766217229757563 | [262,195] | [222,133] | 0 | hSpCas9 | negative selection | 4672236 | 24917096 | 24917118 | 8 | + | 27760321 | HT1080 | viability | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | -0.984667150797564 | [361,282] | [73,54] | -4 | hSpCas9 | negative selection | 4755695 | 24917140 | 24917162 | 8 | - | 27760321 | HT1080 | viability | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | -0.7807735207778501 | [52,41] | [0,21] | -3 | hSpCas9 | negative selection | 4755696 | 24917171 | 24917193 | 8 | - | 27760321 | HT1080 | viability | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | -7.544191704129658 | [525,410] | [0,0] | -9 | hSpCas9 | negative selection | 4755697 | 24917197 | 24917219 | 8 | + | 27760321 | HT1080 | viability | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.7049156659571478 | [336,262] | [253,129] | 4 | hSpCas9 | negative selection | 4755698 | 24917275 | 24917297 | 8 | + | 27760321 | HT1080 | viability | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | 0.05168868944003835 | [195,152] | [30,116] | 0 | hSpCas9 | negative selection | 4755699 | 24917096 | 24917118 | 8 | + | 27760321 | HT29 | viability after 7 days | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | 0.3313973026378463 | [361,282] | [477,198,869] | 5 | hSpCas9 | negative selection | 4839158 | 24917140 | 24917162 | 8 | - | 27760321 | HT29 | viability after 7 days | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | 0.4309647997036734 | [52,41] | [56,24,158] | 6 | hSpCas9 | negative selection | 4839159 | 24917171 | 24917193 | 8 | - | 27760321 | HT29 | viability after 7 days | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | -1.507832433161853 | [525,410] | [228,176,230] | -9 | hSpCas9 | negative selection | 4839160 | 24917197 | 24917219 | 8 | + | 27760321 | HT29 | viability after 7 days | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.14501927273260712 | [336,262] | [402,460,411] | 2 | hSpCas9 | negative selection | 4839161 | 24917275 | 24917297 | 8 | + | 27760321 | HT29 | viability after 7 days | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | 0.6779142009869932 | [195,152] | [244,422,390] | 8 | hSpCas9 | negative selection | 4839162 | 24917096 | 24917118 | 8 | + | 27760321 | HT29 | viability after 25 days | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | 0.34587968404987146 | [361,282] | [372,488,557] | 3 | hSpCas9 | negative selection | 4922621 | 24917140 | 24917162 | 8 | - | 27760321 | HT29 | viability after 25 days | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | 0.2594158633625794 | [52,41] | [32,38,131] | 2 | hSpCas9 | negative selection | 4922622 | 24917171 | 24917193 | 8 | - | 27760321 | HT29 | viability after 25 days | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | -2.9818894473645243 | [525,410] | [38,89,76] | -8 | hSpCas9 | negative selection | 4922623 | 24917197 | 24917219 | 8 | + | 27760321 | HT29 | viability after 25 days | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.428423360506103 | [336,262] | [472,402,511] | 4 | hSpCas9 | negative selection | 4922624 | 24917275 | 24917297 | 8 | + | 27760321 | HT29 | viability after 25 days | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | 0.7240657002137783 | [195,152] | [336,417,220] | 8 | hSpCas9 | negative selection | 4922625 | 24917096 | 24917118 | 8 | + | 27760321 | HT29 | viability after 22 days | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | -0.15673393982139022 | [361,282] | [335,372,293] | -1 | hSpCas9 | negative selection | 5006084 | 24917140 | 24917162 | 8 | - | 27760321 | HT29 | viability after 22 days | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | 0.052559546768505605 | [52,41] | [87,42,38] | 0 | hSpCas9 | negative selection | 5006085 | 24917171 | 24917193 | 8 | - | 27760321 | HT29 | viability after 22 days | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | -4.3947432070961705 | [525,410] | [4,26,45] | -9 | hSpCas9 | negative selection | 5006086 | 24917197 | 24917219 | 8 | + | 27760321 | HT29 | viability after 22 days | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.16362037547702873 | [336,262] | [333,323,509] | 1 | hSpCas9 | negative selection | 5006087 | 24917275 | 24917297 | 8 | + | 27760321 | HT29 | viability after 22 days | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | 1.0188475459697917 | [195,152] | [465,532,223] | 9 | hSpCas9 | negative selection | 5006088 | 24917096 | 24917118 | 8 | + | 27760321 | HT29 | viability after 19 days | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | 0.7584837826287976 | [361,282] | [391,338,1097] | 7 | hSpCas9 | negative selection | 5089547 | 24917140 | 24917162 | 8 | - | 27760321 | HT29 | viability after 19 days | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | 0.4913852459913124 | [52,41] | [124,76,33] | 5 | hSpCas9 | negative selection | 5089548 | 24917171 | 24917193 | 8 | - | 27760321 | HT29 | viability after 19 days | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | -3.1379879661529513 | [525,410] | [34,33,108] | -8 | hSpCas9 | negative selection | 5089549 | 24917197 | 24917219 | 8 | + | 27760321 | HT29 | viability after 19 days | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.13211494112260477 | [336,262] | [453,307,373] | 1 | hSpCas9 | negative selection | 5089550 | 24917275 | 24917297 | 8 | + | 27760321 | HT29 | viability after 19 days | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | 0.8675287333509019 | [195,152] | [210,497,366] | 8 | hSpCas9 | negative selection | 5089551 | 24917096 | 24917118 | 8 | + | 27760321 | HT29 | viability after 16 days | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | 0.5345984113737807 | [361,282] | [484,540,537] | 6 | hSpCas9 | negative selection | 5173010 | 24917140 | 24917162 | 8 | - | 27760321 | HT29 | viability after 16 days | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | -1.5926137850857072 | [52,41] | [13,0,37] | -8 | hSpCas9 | negative selection | 5173011 | 24917171 | 24917193 | 8 | - | 27760321 | HT29 | viability after 16 days | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | -2.7738603895733362 | [525,410] | [82,19,128] | -9 | hSpCas9 | negative selection | 5173012 | 24917197 | 24917219 | 8 | + | 27760321 | HT29 | viability after 16 days | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.49877157519309434 | [336,262] | [517,429,479] | 6 | hSpCas9 | negative selection | 5173013 | 24917275 | 24917297 | 8 | + | 27760321 | HT29 | viability after 16 days | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | 0.5706506416831418 | [195,152] | [415,279,185] | 6 | hSpCas9 | negative selection | 5173014 | 24917096 | 24917118 | 8 | + | 27760321 | HT29 | viability after 13 days | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | -0.4997739192762611 | [361,282] | [180,262,344] | -5 | hSpCas9 | negative selection | 5256473 | 24917140 | 24917162 | 8 | - | 27760321 | HT29 | viability after 13 days | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | -0.6665054968354553 | [52,41] | [0,45,55] | -6 | hSpCas9 | negative selection | 5256474 | 24917171 | 24917193 | 8 | - | 27760321 | HT29 | viability after 13 days | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | -3.6441162033081627 | [525,410] | [47,48,33] | -9 | hSpCas9 | negative selection | 5256475 | 24917197 | 24917219 | 8 | + | 27760321 | HT29 | viability after 13 days | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.11700143339006303 | [336,262] | [297,449,383] | 1 | hSpCas9 | negative selection | 5256476 | 24917275 | 24917297 | 8 | + | 27760321 | HT29 | viability after 13 days | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | 0.26369551938584457 | [195,152] | [188,412,133] | 3 | hSpCas9 | negative selection | 5256477 | 24917096 | 24917118 | 8 | + | 27760321 | HT29 | viability after 10 days | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | 0.45372319796268573 | [361,282] | [519,635,501] | 6 | hSpCas9 | negative selection | 5339936 | 24917140 | 24917162 | 8 | - | 27760321 | HT29 | viability after 10 days | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | -1.5788471396938788 | [52,41] | [36,19,2] | -8 | hSpCas9 | negative selection | 5339937 | 24917171 | 24917193 | 8 | - | 27760321 | HT29 | viability after 10 days | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | -2.282828730661744 | [525,410] | [63,132,162] | -9 | hSpCas9 | negative selection | 5339938 | 24917197 | 24917219 | 8 | + | 27760321 | HT29 | viability after 10 days | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.21049596880584603 | [336,262] | [407,461,430] | 2 | hSpCas9 | negative selection | 5339939 | 24917275 | 24917297 | 8 | + | 27760321 | HT29 | viability after 10 days | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | 0.6139546510659941 | [195,152] | [397,378,226] | 8 | hSpCas9 | negative selection | 5339940 | 24917096 | 24917118 | 8 | + | 27760321 | MOLM13 | viability | CATTTGCAGGAAGCATCACTGG | NEFM | ENSG00000104722 | 0.46444605206413037 | [407,361] | [80,484] | 3 | hSpCas9 | negative selection | 5423399 | 24917140 | 24917162 | 8 | - | 27760321 | MOLM13 | viability | TCTTACTGGATATTGTGATTGG | NEFM | ENSG00000104722 | -1.056911122436536 | [56,52] | [15,13] | -6 | hSpCas9 | negative selection | 5423400 | 24917171 | 24917193 | 8 | - | 27760321 | MOLM13 | viability | AGCTTGGGAGCTTCCACCTTGG | NEFM | ENSG00000104722 | -1.0436849415723792 | [553,525] | [13,261] | -6 | hSpCas9 | negative selection | 5423401 | 24917197 | 24917219 | 8 | + | 27760321 | MOLM13 | viability | GTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | -0.21276711613769894 | [431,336] | [240,138] | -1 | hSpCas9 | negative selection | 5423402 | 24917275 | 24917297 | 8 | + | 27760321 | MOLM13 | viability | ACAGCCATTACAGAGGAATTGG | NEFM | ENSG00000104722 | 0.9558626811888001 | [262,195] | [524,13] | 6 | hSpCas9 | negative selection | 5423403 | 24917175 | 24917198 | 8 | + | 27661255 | K562 | viability | GGTGGAAGCTCCCAAGCTTAAGG | NEFM | ENSG00000104722 | 0.05562128251684717 | [185,251] | [243,126] | 2 | dCas9-KRAB | negative selection | 5496172 | 24917268 | 24917291 | 8 | + | 27661255 | K562 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.05548966856749882 | [1239,1368] | [1236,947] | 2 | dCas9-KRAB | negative selection | 5496173 | 24915658 | 24915681 | 8 | + | 27260156 | BXPC3 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.16725090231721718 | [345] | [337,326,459,524] | 3 | hSpCas9 | negative selection | 5557740 | 24917196 | 24917219 | 8 | + | 27260156 | BXPC3 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.1725922379145861 | [509] | [543,575,572,729] | 4 | hSpCas9 | negative selection | 5621997 | 24915708 | 24915731 | 8 | + | 27260156 | BXPC3 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.5587936091333638 | [276] | [166,158,226,243] | -8 | hSpCas9 | negative selection | 5621998 | 24918564 | 24918587 | 8 | + | 27260156 | BXPC3 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.06887100494553305 | [370] | [254,437,416,546] | 1 | hSpCas9 | negative selection | 5621999 | 24915658 | 24915681 | 8 | + | 27260156 | A673 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.3360842745604128 | [345] | [595,572,479,450] | 7 | hSpCas9 | negative selection | 5678991 | 24917196 | 24917219 | 8 | + | 27260156 | A673 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.18341431537086156 | [509] | [652,699,709,712] | 4 | hSpCas9 | negative selection | 5743248 | 24915708 | 24915731 | 8 | + | 27260156 | A673 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.2753950126637703 | [276] | [333,276,189,306] | -6 | hSpCas9 | negative selection | 5743249 | 24918564 | 24918587 | 8 | + | 27260156 | A673 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.12279871029248418 | [370] | [543,320,544,542] | 3 | hSpCas9 | negative selection | 5743250 | 24915658 | 24915681 | 8 | + | 27260156 | A375 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.360121725609889 | [345] | [436,723,524,425] | 5 | hSpCas9 | negative selection | 5800242 | 24917196 | 24917219 | 8 | + | 27260156 | A375 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.28662495696732926 | [509] | [735,807,875,519] | 4 | hSpCas9 | negative selection | 5864499 | 24915708 | 24915731 | 8 | + | 27260156 | A375 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.848503014600418 | [276] | [129,242,261,100] | -8 | hSpCas9 | negative selection | 5864500 | 24918564 | 24918587 | 8 | + | 27260156 | A375 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.46871858658904153 | [370] | [493,737,815,391] | 7 | hSpCas9 | negative selection | 5864501 | 24915658 | 24915681 | 8 | + | 27260156 | COLO741 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.11511807657181039 | [345] | [659,487,314] | 2 | hSpCas9 | negative selection | 5921493 | 24917196 | 24917219 | 8 | + | 27260156 | COLO741 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.005940140705756991 | [509] | [682,530,742] | 0 | hSpCas9 | negative selection | 5985750 | 24915708 | 24915731 | 8 | + | 27260156 | COLO741 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.6705116763447163 | [276] | [326,205,147] | -8 | hSpCas9 | negative selection | 5985751 | 24918564 | 24918587 | 8 | + | 27260156 | COLO741 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.19457049437176835 | [370] | [435,730,456] | 4 | hSpCas9 | negative selection | 5985752 | 24915658 | 24915681 | 8 | + | 27260156 | CAL120 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.4709413112363907 | [345] | [670,689,442] | 7 | hSpCas9 | negative selection | 6042744 | 24917196 | 24917219 | 8 | + | 27260156 | CAL120 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | -0.0028615167127496177 | [509] | [696,553,657] | 0 | hSpCas9 | negative selection | 6107001 | 24915708 | 24915731 | 8 | + | 27260156 | CAL120 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.6065643929424 | [276] | [258,144,278] | -7 | hSpCas9 | negative selection | 6107002 | 24918564 | 24918587 | 8 | + | 27260156 | CAL120 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.745566757208206 | [370] | [534,984,765] | 9 | hSpCas9 | negative selection | 6107003 | 24915658 | 24915681 | 8 | + | 27260156 | CADOES1 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.5603510796302154 | [345] | [387,332,600,579] | 8 | hSpCas9 | negative selection | 6163995 | 24917196 | 24917219 | 8 | + | 27260156 | CADOES1 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.15790700403625124 | [509] | [528,474,650,458] | 2 | hSpCas9 | negative selection | 6228252 | 24915708 | 24915731 | 8 | + | 27260156 | CADOES1 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.7208165264143833 | [276] | [105,159,161,198] | -8 | hSpCas9 | negative selection | 6228253 | 24918564 | 24918587 | 8 | + | 27260156 | CADOES1 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.05649708994437974 | [370] | [256,308,572,293] | 1 | hSpCas9 | negative selection | 6228254 | 24915658 | 24915681 | 8 | + | 27260156 | EWS502 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.3133381304879167 | [345] | [396,536,484,400] | 5 | hSpCas9 | negative selection | 6285246 | 24917196 | 24917219 | 8 | + | 27260156 | EWS502 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.2292316585866278 | [509] | [725,477,370,970] | 4 | hSpCas9 | negative selection | 6349503 | 24915708 | 24915731 | 8 | + | 27260156 | EWS502 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.4439577961400478 | [276] | [185,207,165,311] | -6 | hSpCas9 | negative selection | 6349504 | 24918564 | 24918587 | 8 | + | 27260156 | EWS502 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.08569287923416596 | [370] | [440,480,328,407] | 1 | hSpCas9 | negative selection | 6349505 | 24915658 | 24915681 | 8 | + | 27260156 | EW8 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.405838975069624 | [345] | [531,293,253,441] | 7 | hSpCas9 | negative selection | 6406497 | 24917196 | 24917219 | 8 | + | 27260156 | EW8 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.0715149608707455 | [509] | [549,484,334,395] | 1 | hSpCas9 | negative selection | 6470754 | 24915708 | 24915731 | 8 | + | 27260156 | EW8 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.18639576860303586 | [276] | [295,232,124,157] | -4 | hSpCas9 | negative selection | 6470755 | 24918564 | 24918587 | 8 | + | 27260156 | EW8 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.12812738352442274 | [370] | [566,275,261,245] | 2 | hSpCas9 | negative selection | 6470756 | 24915658 | 24915681 | 8 | + | 27260156 | CORL105 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.3655714753046228 | [345] | [559,574,465,477] | 6 | hSpCas9 | negative selection | 6527748 | 24917196 | 24917219 | 8 | + | 27260156 | CORL105 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | -0.22755884134655974 | [509] | [553,415,511,560] | -4 | hSpCas9 | negative selection | 6592005 | 24915708 | 24915731 | 8 | + | 27260156 | CORL105 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | 0.16401240184090216 | [276] | [361,327,452,324] | 3 | hSpCas9 | negative selection | 6592006 | 24918564 | 24918587 | 8 | + | 27260156 | CORL105 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.01207727782139234 | [370] | [383,387,578,421] | 0 | hSpCas9 | negative selection | 6592007 | 24915658 | 24915681 | 8 | + | 27260156 | HS294T | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.48112382261163855 | [345] | [129,260,202,148] | 6 | hSpCas9 | negative selection | 6648999 | 24917196 | 24917219 | 8 | + | 27260156 | HS294T | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.05725827326478304 | [509] | [288,155,205,153] | 0 | hSpCas9 | negative selection | 6713256 | 24915708 | 24915731 | 8 | + | 27260156 | HS294T | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.1664651877645026 | [276] | [44,92,134,116] | -2 | hSpCas9 | negative selection | 6713257 | 24918564 | 24918587 | 8 | + | 27260156 | HS294T | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.0035131640401903086 | [370] | [108,108,143,231] | 0 | hSpCas9 | negative selection | 6713258 | 24915658 | 24915681 | 8 | + | 27260156 | HCC44 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.17053531466641125 | [345] | [634,407,484,265] | 2 | hSpCas9 | negative selection | 6770250 | 24917196 | 24917219 | 8 | + | 27260156 | HCC44 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.002468417773766579 | [509] | [677,566,638,447] | 0 | hSpCas9 | negative selection | 6834507 | 24915708 | 24915731 | 8 | + | 27260156 | HCC44 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.3759314004960226 | [276] | [199,307,267,180] | -5 | hSpCas9 | negative selection | 6834508 | 24918564 | 24918587 | 8 | + | 27260156 | HCC44 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.12558105307362444 | [370] | [569,309,464,512] | 2 | hSpCas9 | negative selection | 6834509 | 24915658 | 24915681 | 8 | + | 27260156 | G402 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.2415643993706791 | [345] | [434,486,612,451] | 3 | hSpCas9 | negative selection | 6891501 | 24917196 | 24917219 | 8 | + | 27260156 | G402 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.16291094405651801 | [509] | [593,685,799,688] | 2 | hSpCas9 | negative selection | 6955758 | 24915708 | 24915731 | 8 | + | 27260156 | G402 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.2808291094886357 | [276] | [410,341,110,270] | -4 | hSpCas9 | negative selection | 6955759 | 24918564 | 24918587 | 8 | + | 27260156 | G402 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.8695434082377647 | [370] | [1104,364,374,1442] | 9 | hSpCas9 | negative selection | 6955760 | 24915658 | 24915681 | 8 | + | 27260156 | L33 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.015240863722756848 | [345] | [317,122,306,293] | 0 | hSpCas9 | negative selection | 7012752 | 24917196 | 24917219 | 8 | + | 27260156 | L33 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.15623089457876055 | [509] | [379,208,436,691] | 3 | hSpCas9 | negative selection | 7077009 | 24915708 | 24915731 | 8 | + | 27260156 | L33 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.2867708270694238 | [276] | [188,127,189,106] | -6 | hSpCas9 | negative selection | 7077010 | 24918564 | 24918587 | 8 | + | 27260156 | L33 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.09304001560954447 | [370] | [343,156,294,387] | 2 | hSpCas9 | negative selection | 7077011 | 24915658 | 24915681 | 8 | + | 27260156 | K562 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.011095705289008162 | [345] | [214,359,230,412] | 0 | hSpCas9 | negative selection | 7134003 | 24917196 | 24917219 | 8 | + | 27260156 | K562 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.42317856507371293 | [509] | [640,469,650,652] | 5 | hSpCas9 | negative selection | 7198260 | 24915708 | 24915731 | 8 | + | 27260156 | K562 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.5584632633996971 | [276] | [144,351,30,148] | -6 | hSpCas9 | negative selection | 7198261 | 24918564 | 24918587 | 8 | + | 27260156 | K562 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.5816166388634102 | [370] | [452,608,599,328] | 7 | hSpCas9 | negative selection | 7198262 | 24915658 | 24915681 | 8 | + | 27260156 | HT29 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.11396368498284126 | [345] | [503,454,405,455] | 2 | hSpCas9 | negative selection | 7255254 | 24917196 | 24917219 | 8 | + | 27260156 | HT29 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.4164122843869413 | [509] | [939,979,628,781] | 7 | hSpCas9 | negative selection | 7319511 | 24915708 | 24915731 | 8 | + | 27260156 | HT29 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.4913333890271765 | [276] | [328,265,197,179] | -7 | hSpCas9 | negative selection | 7319512 | 24918564 | 24918587 | 8 | + | 27260156 | HT29 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.37861890372851303 | [370] | [580,654,653,470] | 7 | hSpCas9 | negative selection | 7319513 | 24915658 | 24915681 | 8 | + | 27260156 | MHHES1 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.4195274494529684 | [345] | [728,473,534,386] | 7 | hSpCas9 | negative selection | 7376505 | 24917196 | 24917219 | 8 | + | 27260156 | MHHES1 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.21547051454284194 | [509] | [839,660,602,586] | 4 | hSpCas9 | negative selection | 7440762 | 24915708 | 24915731 | 8 | + | 27260156 | MHHES1 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.7705879800487969 | [276] | [73,313,205,142] | -8 | hSpCas9 | negative selection | 7440763 | 24918564 | 24918587 | 8 | + | 27260156 | MHHES1 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.09555606838575911 | [370] | [701,461,386,292] | 1 | hSpCas9 | negative selection | 7440764 | 24915658 | 24915681 | 8 | + | 27260156 | MEWO | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | -0.10650769024456708 | [345] | [380,197,338] | -2 | hSpCas9 | negative selection | 7497756 | 24917196 | 24917219 | 8 | + | 27260156 | MEWO | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.12759722369208515 | [509] | [609,490,479] | 3 | hSpCas9 | negative selection | 7562013 | 24915708 | 24915731 | 8 | + | 27260156 | MEWO | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.7502136583024523 | [276] | [198,128,142] | -9 | hSpCas9 | negative selection | 7562014 | 24918564 | 24918587 | 8 | + | 27260156 | MEWO | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.23795772428373335 | [370] | [455,399,380] | 5 | hSpCas9 | negative selection | 7562015 | 24915658 | 24915681 | 8 | + | 27260156 | LNCAPCLONEFGC | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.4875203976842386 | [345] | [416,388,464,493] | 7 | hSpCas9 | negative selection | 7619007 | 24917196 | 24917219 | 8 | + | 27260156 | LNCAPCLONEFGC | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | -0.05908994906538676 | [509] | [456,470,460,384] | -1 | hSpCas9 | negative selection | 7683264 | 24915708 | 24915731 | 8 | + | 27260156 | LNCAPCLONEFGC | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.5512055111976346 | [276] | [232,191,101,144] | -7 | hSpCas9 | negative selection | 7683265 | 24918564 | 24918587 | 8 | + | 27260156 | LNCAPCLONEFGC | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.2743102221162072 | [370] | [502,367,512,257] | 4 | hSpCas9 | negative selection | 7683266 | 24915658 | 24915681 | 8 | + | 27260156 | PANC0327 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | -0.01823611083892318 | [345] | [537,149,321,242] | 0 | hSpCas9 | negative selection | 7740258 | 24917196 | 24917219 | 8 | + | 27260156 | PANC0327 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | -0.04775080193947606 | [509] | [507,372,371,513] | 0 | hSpCas9 | negative selection | 7804515 | 24915708 | 24915731 | 8 | + | 27260156 | PANC0327 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.06185104805289798 | [276] | [388,177,260,134] | -1 | hSpCas9 | negative selection | 7804516 | 24918564 | 24918587 | 8 | + | 27260156 | PANC0327 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.16119560355296728 | [370] | [266,404,408,379] | 2 | hSpCas9 | negative selection | 7804517 | 24915658 | 24915681 | 8 | + | 27260156 | NCIH2009 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.11659550135040153 | [345] | [590,504,488] | 1 | hSpCas9 | negative selection | 7861509 | 24917196 | 24917219 | 8 | + | 27260156 | NCIH2009 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.2448553485629284 | [509] | [787,760,972] | 3 | hSpCas9 | negative selection | 7925766 | 24915708 | 24915731 | 8 | + | 27260156 | NCIH2009 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.17270806118092386 | [276] | [473,303,277] | -2 | hSpCas9 | negative selection | 7925767 | 24918564 | 24918587 | 8 | + | 27260156 | NCIH2009 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.43849330869787484 | [370] | [895,670,577] | 6 | hSpCas9 | negative selection | 7925768 | 24915658 | 24915681 | 8 | + | 27260156 | NCIH1373 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.4144549669336474 | [345] | [691,443,440,137] | 4 | hSpCas9 | negative selection | 7982760 | 24917196 | 24917219 | 8 | + | 27260156 | NCIH1373 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.7757270309517867 | [509] | [1790,596,1028,167] | 7 | hSpCas9 | negative selection | 8047017 | 24915708 | 24915731 | 8 | + | 27260156 | NCIH1373 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | 0.31293064332374976 | [276] | [818,269,344,45] | 3 | hSpCas9 | negative selection | 8047018 | 24918564 | 24918587 | 8 | + | 27260156 | NCIH1373 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.7016905608132138 | [370] | [925,934,292,146] | 7 | hSpCas9 | negative selection | 8047019 | 24915658 | 24915681 | 8 | + | 27260156 | PATU8902 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.0797443375418675 | [345] | [544,620,351,561] | 0 | hSpCas9 | negative selection | 8104011 | 24917196 | 24917219 | 8 | + | 27260156 | PATU8902 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.956907521028105 | [509] | [1244,660,1277,2476] | 9 | hSpCas9 | negative selection | 8168268 | 24915708 | 24915731 | 8 | + | 27260156 | PATU8902 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.03483161710643923 | [276] | [429,291,299,516] | 0 | hSpCas9 | negative selection | 8168269 | 24918564 | 24918587 | 8 | + | 27260156 | PATU8902 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.1367219055466385 | [370] | [630,453,478,746] | 1 | hSpCas9 | negative selection | 8168270 | 24915658 | 24915681 | 8 | + | 27260156 | PANC1 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.2976347117551269 | [345] | [279,492,351,358] | 5 | hSpCas9 | negative selection | 8225262 | 24917196 | 24917219 | 8 | + | 27260156 | PANC1 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.39047620617990736 | [509] | [474,1160,356,437] | 6 | hSpCas9 | negative selection | 8289519 | 24915708 | 24915731 | 8 | + | 27260156 | PANC1 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.7042735655850023 | [276] | [192,226,87,96] | -7 | hSpCas9 | negative selection | 8289520 | 24918564 | 24918587 | 8 | + | 27260156 | PANC1 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.4255448587488022 | [370] | [434,406,507,361] | 7 | hSpCas9 | negative selection | 8289521 | 24915658 | 24915681 | 8 | + | 27260156 | PANC0813 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.4801588747684236 | [345] | [699,511,503,562] | 7 | hSpCas9 | negative selection | 8346513 | 24917196 | 24917219 | 8 | + | 27260156 | PANC0813 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.11145598980386813 | [509] | [642,687,504,744] | 1 | hSpCas9 | negative selection | 8410770 | 24915708 | 24915731 | 8 | + | 27260156 | PANC0813 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.39974130290485776 | [276] | [350,292,154,198] | -6 | hSpCas9 | negative selection | 8410771 | 24918564 | 24918587 | 8 | + | 27260156 | PANC0813 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.18145465074490572 | [370] | [696,628,342,333] | 3 | hSpCas9 | negative selection | 8410772 | 24915658 | 24915681 | 8 | + | 27260156 | RDES | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.3886141906490892 | [345] | [441,470,533,664] | 6 | hSpCas9 | negative selection | 8467764 | 24917196 | 24917219 | 8 | + | 27260156 | RDES | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.2312978445239255 | [509] | [456,817,749,759] | 4 | hSpCas9 | negative selection | 8532021 | 24915708 | 24915731 | 8 | + | 27260156 | RDES | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.7610151974258283 | [276] | [87,253,219,203] | -8 | hSpCas9 | negative selection | 8532022 | 24918564 | 24918587 | 8 | + | 27260156 | RDES | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.14219158400680243 | [370] | [388,447,490,577] | 2 | hSpCas9 | negative selection | 8532023 | 24915658 | 24915681 | 8 | + | 27260156 | PC3 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.09891282619781672 | [345] | [365,342,577,212] | 2 | hSpCas9 | negative selection | 8589015 | 24917196 | 24917219 | 8 | + | 27260156 | PC3 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.1488651243860764 | [509] | [385,579,868,554] | 3 | hSpCas9 | negative selection | 8653272 | 24915708 | 24915731 | 8 | + | 27260156 | PC3 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.5843571841963695 | [276] | [140,64,466,178] | -8 | hSpCas9 | negative selection | 8653273 | 24918564 | 24918587 | 8 | + | 27260156 | PC3 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | -0.0015007037803680956 | [370] | [253,377,274,551] | 0 | hSpCas9 | negative selection | 8653274 | 24915658 | 24915681 | 8 | + | 27260156 | PATU8988T | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.5167890527844906 | [345] | [511,563,523,306] | 8 | hSpCas9 | negative selection | 8710266 | 24917196 | 24917219 | 8 | + | 27260156 | PATU8988T | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.2011972429567972 | [509] | [549,592,663,450] | 3 | hSpCas9 | negative selection | 8774523 | 24915708 | 24915731 | 8 | + | 27260156 | PATU8988T | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.4541330928785685 | [276] | [309,268,112,88] | -6 | hSpCas9 | negative selection | 8774524 | 24918564 | 24918587 | 8 | + | 27260156 | PATU8988T | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.40428035673231166 | [370] | [644,469,432,338] | 7 | hSpCas9 | negative selection | 8774525 | 24915658 | 24915681 | 8 | + | 27260156 | T47D | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.2255315899992814 | [345] | [479,420,408,583] | 5 | hSpCas9 | negative selection | 8831517 | 24917196 | 24917219 | 8 | + | 27260156 | T47D | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.25437754237485505 | [509] | [733,642,686,778] | 5 | hSpCas9 | negative selection | 8895774 | 24915708 | 24915731 | 8 | + | 27260156 | T47D | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.4072919299758395 | [276] | [219,276,217,255] | -7 | hSpCas9 | negative selection | 8895775 | 24918564 | 24918587 | 8 | + | 27260156 | T47D | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.3201875852846199 | [370] | [496,470,618,576] | 6 | hSpCas9 | negative selection | 8895776 | 24915658 | 24915681 | 8 | + | 27260156 | SU8686 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.42655049173162973 | [345] | [397,393,425,671] | 7 | hSpCas9 | negative selection | 8952768 | 24917196 | 24917219 | 8 | + | 27260156 | SU8686 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.3489542971656016 | [509] | [617,628,643,692] | 6 | hSpCas9 | negative selection | 9017025 | 24915708 | 24915731 | 8 | + | 27260156 | SU8686 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.08705043198097895 | [276] | [228,232,286,296] | -1 | hSpCas9 | negative selection | 9017026 | 24918564 | 24918587 | 8 | + | 27260156 | SU8686 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.3803378753632905 | [370] | [344,401,496,734] | 6 | hSpCas9 | negative selection | 9017027 | 24915658 | 24915681 | 8 | + | 27260156 | SKES1 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.09505745021700512 | [345] | [596,310,413,193] | 2 | hSpCas9 | negative selection | 9074019 | 24917196 | 24917219 | 8 | + | 27260156 | SKES1 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.2492923384330098 | [509] | [736,536,675,485] | 5 | hSpCas9 | negative selection | 9138276 | 24915708 | 24915731 | 8 | + | 27260156 | SKES1 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.3865290076896404 | [276] | [185,220,245,189] | -7 | hSpCas9 | negative selection | 9138277 | 24918564 | 24918587 | 8 | + | 27260156 | SKES1 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.11416174494733783 | [370] | [370,527,420,300] | 2 | hSpCas9 | negative selection | 9138278 | 24915658 | 24915681 | 8 | + | 27260156 | TOV112D | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | -0.2693014330725322 | [345] | [335,203,190,398] | -5 | hSpCas9 | negative selection | 9195270 | 24917196 | 24917219 | 8 | + | 27260156 | TOV112D | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.3201129848680215 | [509] | [748,716,453,657] | 6 | hSpCas9 | negative selection | 9259527 | 24915708 | 24915731 | 8 | + | 27260156 | TOV112D | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -1.0554769886847044 | [276] | [125,175,160,81] | -9 | hSpCas9 | negative selection | 9259528 | 24918564 | 24918587 | 8 | + | 27260156 | TOV112D | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.29436063277149094 | [370] | [482,505,404,442] | 5 | hSpCas9 | negative selection | 9259529 | 24915658 | 24915681 | 8 | + | 27260156 | TC71 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | -0.16331374872917748 | [345] | [420,317,336,240] | -4 | hSpCas9 | negative selection | 9316521 | 24917196 | 24917219 | 8 | + | 27260156 | TC71 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.19669046773855708 | [509] | [485,806,614,599] | 5 | hSpCas9 | negative selection | 9380778 | 24915708 | 24915731 | 8 | + | 27260156 | TC71 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.43214641911534035 | [276] | [186,130,329,229] | -8 | hSpCas9 | negative selection | 9380779 | 24918564 | 24918587 | 8 | + | 27260156 | TC71 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.15924017564753068 | [370] | [492,408,436,435] | 4 | hSpCas9 | negative selection | 9380780 | 24915658 | 24915681 | 8 | + | 27260156 | TC32 | viability | TCGTCATTTGCGCGAATACCAGG | NEFM | ENSG00000104722 | 0.290028039942819 | [345] | [356,287,494,495] | 5 | hSpCas9 | negative selection | 9437772 | 24917196 | 24917219 | 8 | + | 27260156 | TC32 | viability | GGTCCAACACAAATTTGTCGAGG | NEFM | ENSG00000104722 | 0.2839181989494959 | [509] | [493,489,784,612] | 5 | hSpCas9 | negative selection | 9502029 | 24915708 | 24915731 | 8 | + | 27260156 | TC32 | viability | ATATAGAAATCGCTGCGTACAGG | NEFM | ENSG00000104722 | -0.4032826044223272 | [276] | [171,213,211,173] | -6 | hSpCas9 | negative selection | 9502030 | 24918564 | 24918587 | 8 | + | 27260156 | TC32 | viability | CACTTCACACGCCATAGTAAAGG | NEFM | ENSG00000104722 | 0.10449955273009906 | [370] | [350,338,525,297] | 2 | hSpCas9 | negative selection | 9502031 | 24915601 | 24915624 | 8 | + | 27869803 | HPAFII | viability after 27 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.05828096844939318 | [324] | [244,121,NaN] | 0 | hSpCas9 | negative selection | 9602257 | 24917268 | 24917291 | 8 | + | 27869803 | HPAFII | viability after 27 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.1051247217186716 | [453] | [289,228,NaN] | 0 | hSpCas9 | negative selection | 9602258 | 24915601 | 24915624 | 8 | + | 27869803 | HPAFII | viability after 15 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.08683341386511051 | [324] | [431,332,NaN] | 1 | hSpCas9 | negative selection | 9684706 | 24917268 | 24917291 | 8 | + | 27869803 | HPAFII | viability after 15 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.07154177921842964 | [453] | [685,404,NaN] | 0 | hSpCas9 | negative selection | 9684707 | 24915601 | 24915624 | 8 | + | 27869803 | ASPC1 | viability after 36 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | -0.07986113148468166 | [930] | [525,120,298] | -1 | hSpCas9 | negative selection | 9767155 | 24917268 | 24917291 | 8 | + | 27869803 | ASPC1 | viability after 36 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.16427419317456815 | [1427] | [575,575,243] | -2 | hSpCas9 | negative selection | 9767156 | 24915601 | 24915624 | 8 | + | 27869803 | PATU8988S | viability after 35 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.41682203617310254 | [658] | [275,432,NaN] | 5 | hSpCas9 | negative selection | 9849604 | 24917268 | 24917291 | 8 | + | 27869803 | PATU8988S | viability after 35 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.7473579097774634 | [1058] | [931,498,NaN] | 7 | hSpCas9 | negative selection | 9849605 | 24915601 | 24915624 | 8 | + | 27869803 | PATU8988S | viability after 31 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.6878746247190649 | [658] | [333,536,NaN] | 7 | hSpCas9 | negative selection | 9932053 | 24917268 | 24917291 | 8 | + | 27869803 | PATU8988S | viability after 31 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.5224655108535454 | [1058] | [562,661,NaN] | 6 | hSpCas9 | negative selection | 9932054 | 24915601 | 24915624 | 8 | + | 27869803 | HPAFII | viability after 35 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.12157656527863892 | [324] | [289,53,NaN] | 0 | hSpCas9 | negative selection | 10014502 | 24917268 | 24917291 | 8 | + | 27869803 | HPAFII | viability after 35 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.4604752585883364 | [453] | [351,275,NaN] | 3 | hSpCas9 | negative selection | 10014503 | 24915601 | 24915624 | 8 | + | 27869803 | HPAFII | viability after 31 days | TCAGGACACCATCCAGCAGCTGG | NEFM | ENSG00000104722 | 0.2865052267882572 | [324] | [310,125,NaN] | 2 | hSpCas9 | negative selection | 10096951 | 24917268 | 24917291 | 8 | + | 27869803 | HPAFII | viability after 31 days | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.14227549656951555 | [453] | [307,251,NaN] | 1 | hSpCas9 | negative selection | 10096952 | 24915682 | 24915705 | 8 | - | 28162770 | P31FUJ | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | 0.7572823267205386 | [72] | [144] | 8 | hSpCas9 | negative selection | 10199210 | 24918285 | 24918308 | 8 | + | 28162770 | P31FUJ | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -3.3906543735561163 | [356] | [39] | -9 | hSpCas9 | negative selection | 10199211 | 24917157 | 24917180 | 8 | + | 28162770 | P31FUJ | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 1.4409695632646338 | [20] | [66] | 9 | hSpCas9 | negative selection | 10199212 | 24917241 | 24917264 | 8 | + | 28162770 | P31FUJ | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.31711334920757694 | [124] | [182] | 3 | hSpCas9 | negative selection | 10199213 | 24917268 | 24917291 | 8 | + | 28162770 | P31FUJ | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.4759664979211756 | [371] | [607] | 5 | hSpCas9 | negative selection | 10199214 | 24917652 | 24917675 | 8 | + | 28162770 | P31FUJ | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -0.929410060964444 | [46] | [28] | -6 | hSpCas9 | negative selection | 10199215 | 24917985 | 24918008 | 8 | + | 28162770 | P31FUJ | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 0.4982018315131107 | [96] | [160] | 5 | hSpCas9 | negative selection | 10199216 | 24918156 | 24918179 | 8 | + | 28162770 | P31FUJ | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -2.3971890223152608 | [129] | [28] | -8 | hSpCas9 | negative selection | 10199217 | 24918169 | 24918192 | 8 | + | 28162770 | P31FUJ | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | -1.8177647051355343 | [2] | [0] | -8 | hSpCas9 | negative selection | 10199218 | 24918267 | 24918290 | 8 | + | 28162770 | P31FUJ | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -4.422626763294396 | [72] | [3] | -9 | hSpCas9 | negative selection | 10199219 | 24915682 | 24915705 | 8 | - | 28162770 | TF1 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | NaN | [NaN] | [132] | 1 | hSpCas9 | negative selection | 10368576 | 24918285 | 24918308 | 8 | + | 28162770 | TF1 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | NaN | [NaN] | [32] | 1 | hSpCas9 | negative selection | 10368577 | 24917157 | 24917180 | 8 | + | 28162770 | TF1 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | NaN | [NaN] | [2] | 1 | hSpCas9 | negative selection | 10368578 | 24917241 | 24917264 | 8 | + | 28162770 | TF1 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | NaN | [NaN] | [189] | 1 | hSpCas9 | negative selection | 10368579 | 24917268 | 24917291 | 8 | + | 28162770 | TF1 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | NaN | [NaN] | [558] | 1 | hSpCas9 | negative selection | 10368580 | 24917652 | 24917675 | 8 | + | 28162770 | TF1 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | NaN | [NaN] | [3] | 1 | hSpCas9 | negative selection | 10368581 | 24917985 | 24918008 | 8 | + | 28162770 | TF1 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | NaN | [NaN] | [70] | 1 | hSpCas9 | negative selection | 10368582 | 24918156 | 24918179 | 8 | + | 28162770 | TF1 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | NaN | [NaN] | [37] | 1 | hSpCas9 | negative selection | 10368583 | 24918169 | 24918192 | 8 | + | 28162770 | TF1 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | NaN | [NaN] | [0] | 1 | hSpCas9 | negative selection | 10368584 | 24918267 | 24918290 | 8 | + | 28162770 | TF1 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | NaN | [NaN] | [5] | 1 | hSpCas9 | negative selection | 10368585 | 24915682 | 24915705 | 8 | - | 28162770 | SKM1 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | -0.6203678368523551 | [19] | [22] | -5 | hSpCas9 | negative selection | 10537942 | 24918285 | 24918308 | 8 | + | 28162770 | SKM1 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -2.3756000278338263 | [90] | [30] | -8 | hSpCas9 | negative selection | 10537943 | 24917157 | 24917180 | 8 | + | 28162770 | SKM1 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 0.1779983019779947 | [12] | [25] | 1 | hSpCas9 | negative selection | 10537944 | 24917241 | 24917264 | 8 | + | 28162770 | SKM1 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.258918297361562 | [25] | [54] | 2 | hSpCas9 | negative selection | 10537945 | 24917268 | 24917291 | 8 | + | 28162770 | SKM1 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.8881025559766346 | [102] | [336] | 8 | hSpCas9 | negative selection | 10537946 | 24917652 | 24917675 | 8 | + | 28162770 | SKM1 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -2.1439297929093675 | [19] | [7] | -8 | hSpCas9 | negative selection | 10537947 | 24917985 | 24918008 | 8 | + | 28162770 | SKM1 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 0.1779983019779945 | [13] | [27] | 1 | hSpCas9 | negative selection | 10537948 | 24918156 | 24918179 | 8 | + | 28162770 | SKM1 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -3.544467722493097 | [32] | [4] | -9 | hSpCas9 | negative selection | 10537949 | 24918169 | 24918192 | 8 | + | 28162770 | SKM1 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | 0.7629608026991512 | [0] | [2] | 7 | hSpCas9 | negative selection | 10537950 | 24918267 | 24918290 | 8 | + | 28162770 | SKM1 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -5.069929211465591 | [18] | [0] | -9 | hSpCas9 | negative selection | 10537951 | 24915682 | 24915705 | 8 | - | 28162770 | SKM1 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | -0.6203678368523551 | [19] | [22] | -5 | hSpCas9 | negative selection | 10707308 | 24918285 | 24918308 | 8 | + | 28162770 | SKM1 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -2.3756000278338263 | [90] | [30] | -8 | hSpCas9 | negative selection | 10707309 | 24917157 | 24917180 | 8 | + | 28162770 | SKM1 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 0.1779983019779947 | [12] | [25] | 1 | hSpCas9 | negative selection | 10707310 | 24917241 | 24917264 | 8 | + | 28162770 | SKM1 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.258918297361562 | [25] | [54] | 2 | hSpCas9 | negative selection | 10707311 | 24917268 | 24917291 | 8 | + | 28162770 | SKM1 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.8881025559766346 | [102] | [336] | 8 | hSpCas9 | negative selection | 10707312 | 24917652 | 24917675 | 8 | + | 28162770 | SKM1 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -2.1439297929093675 | [19] | [7] | -8 | hSpCas9 | negative selection | 10707313 | 24917985 | 24918008 | 8 | + | 28162770 | SKM1 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 0.1779983019779945 | [13] | [27] | 1 | hSpCas9 | negative selection | 10707314 | 24918156 | 24918179 | 8 | + | 28162770 | SKM1 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -3.544467722493097 | [32] | [4] | -9 | hSpCas9 | negative selection | 10707315 | 24918169 | 24918192 | 8 | + | 28162770 | SKM1 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | 0.7629608026991512 | [0] | [2] | 7 | hSpCas9 | negative selection | 10707316 | 24918267 | 24918290 | 8 | + | 28162770 | SKM1 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -5.069929211465591 | [18] | [0] | -9 | hSpCas9 | negative selection | 10707317 | 24915682 | 24915705 | 8 | - | 28162770 | PL21 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | 0.042598337502840256 | [86] | [38] | 0 | hSpCas9 | negative selection | 10876674 | 24918285 | 24918308 | 8 | + | 28162770 | PL21 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -2.9857269308220133 | [272] | [14] | -9 | hSpCas9 | negative selection | 10876675 | 24917157 | 24917180 | 8 | + | 28162770 | PL21 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 1.697639273960137 | [33] | [47] | 9 | hSpCas9 | negative selection | 10876676 | 24917241 | 24917264 | 8 | + | 28162770 | PL21 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | -1.2737915738430923 | [99] | [17] | -7 | hSpCas9 | negative selection | 10876677 | 24917268 | 24917291 | 8 | + | 28162770 | PL21 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.023550882765996928 | [433] | [191] | 0 | hSpCas9 | negative selection | 10876678 | 24917652 | 24917675 | 8 | + | 28162770 | PL21 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -2.384822886231836 | [59] | [4] | -8 | hSpCas9 | negative selection | 10876679 | 24917985 | 24918008 | 8 | + | 28162770 | PL21 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | -3.1397103883953053 | [80] | [3] | -9 | hSpCas9 | negative selection | 10876680 | 24918156 | 24918179 | 8 | + | 28162770 | PL21 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -0.9977997631225886 | [77] | [16] | -6 | hSpCas9 | negative selection | 10876681 | 24918169 | 24918192 | 8 | + | 28162770 | PL21 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | 1.3700646159316325 | [7] | [8] | 9 | hSpCas9 | negative selection | 10876682 | 24918267 | 24918290 | 8 | + | 28162770 | PL21 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -3.9496075050153623 | [70] | [1] | -9 | hSpCas9 | negative selection | 10876683 | 24915682 | 24915705 | 8 | - | 28162770 | P31FUJ | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | 0.7572823267205386 | [72] | [144] | 8 | hSpCas9 | negative selection | 11046040 | 24918285 | 24918308 | 8 | + | 28162770 | P31FUJ | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -3.3906543735561163 | [356] | [39] | -9 | hSpCas9 | negative selection | 11046041 | 24917157 | 24917180 | 8 | + | 28162770 | P31FUJ | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 1.4409695632646338 | [20] | [66] | 9 | hSpCas9 | negative selection | 11046042 | 24917241 | 24917264 | 8 | + | 28162770 | P31FUJ | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.31711334920757694 | [124] | [182] | 3 | hSpCas9 | negative selection | 11046043 | 24917268 | 24917291 | 8 | + | 28162770 | P31FUJ | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.4759664979211756 | [371] | [607] | 5 | hSpCas9 | negative selection | 11046044 | 24917652 | 24917675 | 8 | + | 28162770 | P31FUJ | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -0.929410060964444 | [46] | [28] | -6 | hSpCas9 | negative selection | 11046045 | 24917985 | 24918008 | 8 | + | 28162770 | P31FUJ | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 0.4982018315131107 | [96] | [160] | 5 | hSpCas9 | negative selection | 11046046 | 24918156 | 24918179 | 8 | + | 28162770 | P31FUJ | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -2.3971890223152608 | [129] | [28] | -8 | hSpCas9 | negative selection | 11046047 | 24918169 | 24918192 | 8 | + | 28162770 | P31FUJ | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | -1.8177647051355343 | [2] | [0] | -8 | hSpCas9 | negative selection | 11046048 | 24918267 | 24918290 | 8 | + | 28162770 | P31FUJ | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -4.422626763294396 | [72] | [3] | -9 | hSpCas9 | negative selection | 11046049 | 24915682 | 24915705 | 8 | - | 28162770 | OCIAML5 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | -0.2469261882052104 | [70] | [107] | -2 | hSpCas9 | negative selection | 11215406 | 24918285 | 24918308 | 8 | + | 28162770 | OCIAML5 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -3.960591027642166 | [137] | [15] | -9 | hSpCas9 | negative selection | 11215407 | 24917157 | 24917180 | 8 | + | 28162770 | OCIAML5 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 0.7098123167441177 | [20] | [61] | 6 | hSpCas9 | negative selection | 11215408 | 24917241 | 24917264 | 8 | + | 28162770 | OCIAML5 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.1586598357290615 | [66] | [134] | 1 | hSpCas9 | negative selection | 11215409 | 24917268 | 24917291 | 8 | + | 28162770 | OCIAML5 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.05962764079935923 | [249] | [432] | 0 | hSpCas9 | negative selection | 11215410 | 24917652 | 24917675 | 8 | + | 28162770 | OCIAML5 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -0.7740640588627237 | [17] | [18] | -5 | hSpCas9 | negative selection | 11215411 | 24917985 | 24918008 | 8 | + | 28162770 | OCIAML5 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 1.0919770231619874 | [45] | [176] | 8 | hSpCas9 | negative selection | 11215412 | 24918156 | 24918179 | 8 | + | 28162770 | OCIAML5 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -7.2614575070016985 | [84] | [0] | -9 | hSpCas9 | negative selection | 11215413 | 24918169 | 24918192 | 8 | + | 28162770 | OCIAML5 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | -0.5041432674436903 | [10] | [13] | -3 | hSpCas9 | negative selection | 11215414 | 24918267 | 24918290 | 8 | + | 28162770 | OCIAML5 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -6.606954073027466 | [53] | [0] | -9 | hSpCas9 | negative selection | 11215415 | 24915682 | 24915705 | 8 | - | 28162770 | EOL1 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | -0.49359563857613087 | [154] | [57] | -4 | hSpCas9 | negative selection | 11384772 | 24918285 | 24918308 | 8 | + | 28162770 | EOL1 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -1.632086006092127 | [352] | [59] | -7 | hSpCas9 | negative selection | 11384773 | 24917157 | 24917180 | 8 | + | 28162770 | EOL1 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 1.3157385288950108 | [60] | [79] | 9 | hSpCas9 | negative selection | 11384774 | 24917241 | 24917264 | 8 | + | 28162770 | EOL1 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.7486979361711169 | [182] | [161] | 6 | hSpCas9 | negative selection | 11384775 | 24917268 | 24917291 | 8 | + | 28162770 | EOL1 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.12709321187606837 | [710] | [342] | -1 | hSpCas9 | negative selection | 11384776 | 24917652 | 24917675 | 8 | + | 28162770 | EOL1 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -1.688429105320218 | [103] | [16] | -8 | hSpCas9 | negative selection | 11384777 | 24917985 | 24918008 | 8 | + | 28162770 | EOL1 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 0.28170435476887823 | [88] | [56] | 2 | hSpCas9 | negative selection | 11384778 | 24918156 | 24918179 | 8 | + | 28162770 | EOL1 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -5.332840071122117 | [152] | [1] | -9 | hSpCas9 | negative selection | 11384779 | 24918169 | 24918192 | 8 | + | 28162770 | EOL1 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | 0.33958527084937806 | [11] | [7] | 3 | hSpCas9 | negative selection | 11384780 | 24918267 | 24918290 | 8 | + | 28162770 | EOL1 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -3.9334332235570377 | [86] | [2] | -9 | hSpCas9 | negative selection | 11384781 | 24915682 | 24915705 | 8 | - | 28162770 | MOLM13 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | -1.0572016631991787 | [117] | [40] | -5 | hSpCas9 | negative selection | 11554138 | 24918285 | 24918308 | 8 | + | 28162770 | MOLM13 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -4.881821869856322 | [366] | [8] | -9 | hSpCas9 | negative selection | 11554139 | 24917157 | 24917180 | 8 | + | 28162770 | MOLM13 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 1.3366448482663262 | [45] | [83] | 8 | hSpCas9 | negative selection | 11554140 | 24917241 | 24917264 | 8 | + | 28162770 | MOLM13 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 1.1540739324445362 | [132] | [213] | 8 | hSpCas9 | negative selection | 11554141 | 24917268 | 24917291 | 8 | + | 28162770 | MOLM13 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.596404122067259 | [482] | [527] | 4 | hSpCas9 | negative selection | 11554142 | 24917652 | 24917675 | 8 | + | 28162770 | MOLM13 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -2.458110037011645 | [75] | [9] | -8 | hSpCas9 | negative selection | 11554143 | 24917985 | 24918008 | 8 | + | 28162770 | MOLM13 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 0.6754848009529464 | [83] | [96] | 5 | hSpCas9 | negative selection | 11554144 | 24918156 | 24918179 | 8 | + | 28162770 | MOLM13 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -7.124567655723502 | [192] | [0] | -9 | hSpCas9 | negative selection | 11554145 | 24918169 | 24918192 | 8 | + | 28162770 | MOLM13 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | -2.9915422370927187 | [10] | [0] | -8 | hSpCas9 | negative selection | 11554146 | 24918267 | 24918290 | 8 | + | 28162770 | MOLM13 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -6.474625123794661 | [122] | [0] | -9 | hSpCas9 | negative selection | 11554147 | 24915682 | 24915705 | 8 | - | 28162770 | HEL | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | 1.5510226629087418 | [137] | [258] | 9 | hSpCas9 | negative selection | 11723504 | 24918285 | 24918308 | 8 | + | 28162770 | HEL | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -4.789106954965041 | [258] | [5] | -9 | hSpCas9 | negative selection | 11723505 | 24917157 | 24917180 | 8 | + | 28162770 | HEL | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 2.3846706790599126 | [28] | [96] | 9 | hSpCas9 | negative selection | 11723506 | 24917241 | 24917264 | 8 | + | 28162770 | HEL | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.7534422964065768 | [162] | [175] | 6 | hSpCas9 | negative selection | 11723507 | 24917268 | 24917291 | 8 | + | 28162770 | HEL | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.5349355424658422 | [499] | [463] | 4 | hSpCas9 | negative selection | 11723508 | 24917652 | 24917675 | 8 | + | 28162770 | HEL | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -4.357261167999643 | [63] | [1] | -9 | hSpCas9 | negative selection | 11723509 | 24917985 | 24918008 | 8 | + | 28162770 | HEL | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | -0.26210393495930284 | [87] | [46] | -2 | hSpCas9 | negative selection | 11723510 | 24918156 | 24918179 | 8 | + | 28162770 | HEL | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -2.0629758281814095 | [136] | [20] | -8 | hSpCas9 | negative selection | 11723511 | 24918169 | 24918192 | 8 | + | 28162770 | HEL | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | -1.942223668720799 | [5] | [0] | -8 | hSpCas9 | negative selection | 11723512 | 24918267 | 24918290 | 8 | + | 28162770 | HEL | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -5.865055808198339 | [90] | [0] | -9 | hSpCas9 | negative selection | 11723513 | 24915682 | 24915705 | 8 | - | 28162770 | MV411 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | -0.8877220324988605 | [122] | [55] | -6 | hSpCas9 | negative selection | 11892870 | 24918285 | 24918308 | 8 | + | 28162770 | MV411 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -3.4263342168962367 | [267] | [20] | -9 | hSpCas9 | negative selection | 11892871 | 24917157 | 24917180 | 8 | + | 28162770 | MV411 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 0.20436882889088936 | [33] | [32] | 1 | hSpCas9 | negative selection | 11892872 | 24917241 | 24917264 | 8 | + | 28162770 | MV411 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 1.9396332748289586 | [107] | [348] | 9 | hSpCas9 | negative selection | 11892873 | 24917268 | 24917291 | 8 | + | 28162770 | MV411 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.07393202444421343 | [352] | [312] | 0 | hSpCas9 | negative selection | 11892874 | 24917652 | 24917675 | 8 | + | 28162770 | MV411 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | 0.18731655834520433 | [48] | [46] | 1 | hSpCas9 | negative selection | 11892875 | 24917985 | 24918008 | 8 | + | 28162770 | MV411 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 0.5002036211627419 | [46] | [55] | 4 | hSpCas9 | negative selection | 11892876 | 24918156 | 24918179 | 8 | + | 28162770 | MV411 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -1.1740262176555012 | [74] | [27] | -6 | hSpCas9 | negative selection | 11892877 | 24918169 | 24918192 | 8 | + | 28162770 | MV411 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | -2.7525624492172245 | [7] | [0] | -9 | hSpCas9 | negative selection | 11892878 | 24918267 | 24918290 | 8 | + | 28162770 | MV411 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -6.144879871995985 | [83] | [0] | -9 | hSpCas9 | negative selection | 11892879 | 24915682 | 24915705 | 8 | - | 28162770 | MONOMAC1 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | 0.47538849491194185 | [63] | [101] | 5 | hSpCas9 | negative selection | 12062236 | 24918285 | 24918308 | 8 | + | 28162770 | MONOMAC1 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -2.6718164300302867 | [188] | [33] | -9 | hSpCas9 | negative selection | 12062237 | 24917157 | 24917180 | 8 | + | 28162770 | MONOMAC1 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | -0.4485756140555184 | [24] | [20] | -4 | hSpCas9 | negative selection | 12062238 | 24917241 | 24917264 | 8 | + | 28162770 | MONOMAC1 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | -0.05443245161675325 | [76] | [84] | 0 | hSpCas9 | negative selection | 12062239 | 24917268 | 24917291 | 8 | + | 28162770 | MONOMAC1 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.021357170891434185 | [277] | [313] | 0 | hSpCas9 | negative selection | 12062240 | 24917652 | 24917675 | 8 | + | 28162770 | MONOMAC1 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -2.4340760443604026 | [32] | [6] | -9 | hSpCas9 | negative selection | 12062241 | 24917985 | 24918008 | 8 | + | 28162770 | MONOMAC1 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 1.7912813478928111 | [30] | [122] | 9 | hSpCas9 | negative selection | 12062242 | 24918156 | 24918179 | 8 | + | 28162770 | MONOMAC1 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | 0.46809600234558596 | [69] | [110] | 4 | hSpCas9 | negative selection | 12062243 | 24918169 | 24918192 | 8 | + | 28162770 | MONOMAC1 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | 1.6774322708565874 | [5] | [21] | 9 | hSpCas9 | negative selection | 12062244 | 24918267 | 24918290 | 8 | + | 28162770 | MONOMAC1 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -4.346783966564236 | [70] | [3] | -9 | hSpCas9 | negative selection | 12062245 | 24915682 | 24915705 | 8 | - | 28162770 | OCIAML2 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | -0.5472511068450738 | [28] | [109] | -4 | hSpCas9 | negative selection | 12231602 | 24918285 | 24918308 | 8 | + | 28162770 | OCIAML2 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -2.724386417487944 | [30] | [25] | -9 | hSpCas9 | negative selection | 12231603 | 24917157 | 24917180 | 8 | + | 28162770 | OCIAML2 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | -0.07831240246340077 | [7] | [41] | 0 | hSpCas9 | negative selection | 12231604 | 24917241 | 24917264 | 8 | + | 28162770 | OCIAML2 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | 0.3263831525939839 | [19] | [138] | 3 | hSpCas9 | negative selection | 12231605 | 24917268 | 24917291 | 8 | + | 28162770 | OCIAML2 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | -0.04436507054006311 | [87] | [472] | 0 | hSpCas9 | negative selection | 12231606 | 24917652 | 24917675 | 8 | + | 28162770 | OCIAML2 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -2.1811232080471763 | [8] | [10] | -8 | hSpCas9 | negative selection | 12231607 | 24917985 | 24918008 | 8 | + | 28162770 | OCIAML2 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | -0.10805974585745304 | [13] | [71] | -1 | hSpCas9 | negative selection | 12231608 | 24918156 | 24918179 | 8 | + | 28162770 | OCIAML2 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -3.7601364424371466 | [21] | [8] | -9 | hSpCas9 | negative selection | 12231609 | 24918169 | 24918192 | 8 | + | 28162770 | OCIAML2 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | -0.8856673245210054 | [0] | [2] | -6 | hSpCas9 | negative selection | 12231610 | 24918267 | 24918290 | 8 | + | 28162770 | OCIAML2 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -6.277984747299765 | [13] | [0] | -9 | hSpCas9 | negative selection | 12231611 | 24915682 | 24915705 | 8 | - | 28162770 | OCIAML3 | viability | GAGCCATCTTGACGTTGAGGAGG | NEFM | ENSG00000104722 | 0.07584375798350607 | [21] | [69] | 0 | hSpCas9 | negative selection | 12400968 | 24918285 | 24918308 | 8 | + | 28162770 | OCIAML3 | viability | GGAGGTAGAGCAGGAGACCAAGG | NEFM | ENSG00000104722 | -0.878737117257276 | [66] | [109] | -6 | hSpCas9 | negative selection | 12400969 | 24917157 | 24917180 | 8 | + | 28162770 | OCIAML3 | viability | TAAGATTCAGAAACCCAAGGTGG | NEFM | ENSG00000104722 | 0.9420452599160463 | [4] | [28] | 7 | hSpCas9 | negative selection | 12400970 | 24917241 | 24917264 | 8 | + | 28162770 | OCIAML3 | viability | GGAGGATGAGAAGTCAGAAATGG | NEFM | ENSG00000104722 | -0.46155734430051365 | [25] | [56] | -4 | hSpCas9 | negative selection | 12400971 | 24917268 | 24917291 | 8 | + | 28162770 | OCIAML3 | viability | GGCCCTGACAGCCATTACAGAGG | NEFM | ENSG00000104722 | 0.0831712316179668 | [100] | [322] | 0 | hSpCas9 | negative selection | 12400972 | 24917652 | 24917675 | 8 | + | 28162770 | OCIAML3 | viability | GGAGCTGGTGGCAGATGCCAAGG | NEFM | ENSG00000104722 | -1.5008982359326815 | [14] | [15] | -7 | hSpCas9 | negative selection | 12400973 | 24917985 | 24918008 | 8 | + | 28162770 | OCIAML3 | viability | GGAAGCTCCCAAGGAAGAGAAGG | NEFM | ENSG00000104722 | 0.6386531164661116 | [9] | [46] | 6 | hSpCas9 | negative selection | 12400974 | 24918156 | 24918179 | 8 | + | 28162770 | OCIAML3 | viability | ACTGCAGCAGGAGAAAGAGAAGG | NEFM | ENSG00000104722 | -0.49779232506485993 | [28] | [61] | -4 | hSpCas9 | negative selection | 12400975 | 24918169 | 24918192 | 8 | + | 28162770 | OCIAML3 | viability | AAAGAGAAGGAGAAAGCGGGAGG | NEFM | ENSG00000104722 | -3.17897014104532 | [2] | [0] | -9 | hSpCas9 | negative selection | 12400976 | 24918267 | 24918290 | 8 | + | 28162770 | OCIAML3 | viability | GGAGGTAGAAGGAAAAGAGGAGG | NEFM | ENSG00000104722 | -5.841935153767749 | [18] | [0] | -9 | hSpCas9 | negative selection | 12400977 |