Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6787
• Symbol:NEK4
• Description:NIMA related kinase 4

DataSource: http://genomecrispr.dkfz.de/#!/results/NEK4

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
52770665	52770688	3	-	26472758	Jiyoye	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.0215216890081239	[80]	[61]	0	hSpCas9	negative selection	107686
52744257	52744280	3	-	26472758	Jiyoye	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	-0.9083264442220559	[111]	[44]	-6	hSpCas9	negative selection	107687
52766240	52766263	3	+	26472758	Jiyoye	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	2.0152214953400707	[61]	[188]	8	hSpCas9	negative selection	107688
52752175	52752198	3	-	26472758	Jiyoye	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	0.1711080232723492	[52]	[44]	1	hSpCas9	negative selection	107689
52752158	52752181	3	-	26472758	Jiyoye	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-0.7162070339994087	[60]	[27]	-5	hSpCas9	negative selection	107690
52743408	52743431	3	-	26472758	Jiyoye	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	1.3379127190687594	[31]	[60]	7	hSpCas9	negative selection	107691
52770689	52770712	3	-	26472758	Jiyoye	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-4.533662546025983	[214]	[6]	-9	hSpCas9	negative selection	107692
52752277	52752300	3	+	26472758	Jiyoye	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	0.7656293524183496	[77]	[99]	5	hSpCas9	negative selection	107693
52752001	52752024	3	+	26472758	Jiyoye	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	1.2392307441918018	[90]	[161]	7	hSpCas9	negative selection	107694
52746838	52746861	3	+	26472758	Jiyoye	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	-0.03823576681648916	[127]	[93]	0	hSpCas9	negative selection	107695
52770665	52770688	3	-	26472758	KBM7	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	-0.4178198258689184	[309,207]	[46,127]	-4	hSpCas9	negative selection	298804
52744257	52744280	3	-	26472758	KBM7	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	0.1356294264363423	[387,447]	[245,193]	1	hSpCas9	negative selection	298805
52766240	52766263	3	+	26472758	KBM7	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.8229101466062752	[700,340]	[511,337]	8	hSpCas9	negative selection	298806
52752175	52752198	3	-	26472758	KBM7	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	0.399174443067968	[230,184]	[200,62]	4	hSpCas9	negative selection	298807
52752158	52752181	3	-	26472758	KBM7	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-1.197278160362702	[150,117]	[10,41]	-7	hSpCas9	negative selection	298808
52743408	52743431	3	-	26472758	KBM7	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	0.4675552360497144	[199,122]	[84,118]	5	hSpCas9	negative selection	298809
52770689	52770712	3	-	26472758	KBM7	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-2.8856447111716186	[440,407]	[16,35]	-9	hSpCas9	negative selection	298810
52752277	52752300	3	+	26472758	KBM7	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	0.2576375714409774	[301,318]	[215,139]	2	hSpCas9	negative selection	298811
52752001	52752024	3	+	26472758	KBM7	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.6578531785070015	[685,534]	[451,446]	7	hSpCas9	negative selection	298812
52746838	52746861	3	+	26472758	KBM7	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.09321594322474502	[678,570]	[354,273]	0	hSpCas9	negative selection	298813
52770665	52770688	3	-	26472758	Raji	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	1.3611401276193824	[103]	[61]	9	hSpCas9	negative selection	489922
52744257	52744280	3	-	26472758	Raji	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	1.0420920751218803	[112]	[53]	8	hSpCas9	negative selection	489923
52766240	52766263	3	+	26472758	Raji	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.89493391728473	[240]	[103]	7	hSpCas9	negative selection	489924
52752175	52752198	3	-	26472758	Raji	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	0.0015888713510026076	[98]	[22]	0	hSpCas9	negative selection	489925
52752158	52752181	3	-	26472758	Raji	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-0.07848300993773427	[90]	[19]	0	hSpCas9	negative selection	489926
52743408	52743431	3	-	26472758	Raji	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	1.0264635399900321	[54]	[25]	8	hSpCas9	negative selection	489927
52770689	52770712	3	-	26472758	Raji	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-2.1150088859628484	[279]	[14]	-8	hSpCas9	negative selection	489928
52752277	52752300	3	+	26472758	Raji	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	1.3777412820132522	[130]	[78]	9	hSpCas9	negative selection	489929
52752001	52752024	3	+	26472758	Raji	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.5160232634542925	[225]	[74]	5	hSpCas9	negative selection	489930
52746838	52746861	3	+	26472758	Raji	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.33565252304671683	[279]	[81]	3	hSpCas9	negative selection	489931
52770665	52770688	3	-	26472758	K562	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.442585033323006	[162]	[186]	3	hSpCas9	negative selection	681040
52744257	52744280	3	-	26472758	K562	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	1.68008418833202	[216]	[586]	9	hSpCas9	negative selection	681041
52766240	52766263	3	+	26472758	K562	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.7315692050308329	[477]	[669]	6	hSpCas9	negative selection	681042
52752175	52752198	3	-	26472758	K562	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	0.5636476729528539	[213]	[266]	4	hSpCas9	negative selection	681043
52752158	52752181	3	-	26472758	K562	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-1.1508825535511347	[120]	[45]	-6	hSpCas9	negative selection	681044
52743408	52743431	3	-	26472758	K562	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	0.47118958951346923	[93]	[109]	4	hSpCas9	negative selection	681045
52770689	52770712	3	-	26472758	K562	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-6.989200949093256	[300]	[1]	-9	hSpCas9	negative selection	681046
52752277	52752300	3	+	26472758	K562	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	0.02851033990019758	[258]	[222]	0	hSpCas9	negative selection	681047
52752001	52752024	3	+	26472758	K562	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.7930039076878419	[414]	[606]	6	hSpCas9	negative selection	681048
52746838	52746861	3	+	26472758	K562	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	-0.14908561006275567	[531]	[404]	-1	hSpCas9	negative selection	681049
52743424	52743447	3	-	26627737	DLD1	viability	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	1.0903525333274242	[199]	[139,148,113]	8	hSpCas9	negative selection	822676
52746796	52746819	3	+	26627737	DLD1	viability	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.7081380413633421	[476]	[281,249,204]	7	hSpCas9	negative selection	822677
52751913	52751936	3	+	26627737	DLD1	viability	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	0.8859084764543843	[251]	[106,246,94]	8	hSpCas9	negative selection	822678
52766240	52766263	3	+	26627737	DLD1	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.6603341343242464	[1084]	[585,397,606]	6	hSpCas9	negative selection	822679
52768541	52768564	3	-	26627737	DLD1	viability	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.14135648550287372	[1244]	[517,396,378]	1	hSpCas9	negative selection	822680
52770669	52770692	3	-	26627737	DLD1	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	1.3438042498083522	[195]	[130,153,177]	9	hSpCas9	negative selection	822681
52743424	52743447	3	-	26627737	GBM cells	viability after 5 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.37994549810979084	[164]	[82,52]	-5	hSpCas9	negative selection	904991
52746796	52746819	3	+	26627737	GBM cells	viability after 5 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.5717910332903278	[312]	[228,269]	8	hSpCas9	negative selection	904992
52751913	52751936	3	+	26627737	GBM cells	viability after 5 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	0.3714016463484291	[79]	[49,60]	5	hSpCas9	negative selection	904993
52766240	52766263	3	+	26627737	GBM cells	viability after 5 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.37052485614202435	[586]	[261,224]	-5	hSpCas9	negative selection	904994
52768541	52768564	3	-	26627737	GBM cells	viability after 5 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.07995882532888143	[358]	[179,226]	1	hSpCas9	negative selection	904995
52770669	52770692	3	-	26627737	GBM cells	viability after 5 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-1.0549569543851132	[276]	[63,78]	-9	hSpCas9	negative selection	904996
52743424	52743447	3	-	26627737	GBM cells	viability after 13 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.1024216959123021	[164]	[105,64]	-1	hSpCas9	negative selection	987306
52746796	52746819	3	+	26627737	GBM cells	viability after 13 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.8521389992621757	[312]	[337,280]	8	hSpCas9	negative selection	987307
52751913	52751936	3	+	26627737	GBM cells	viability after 13 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	0.6143403948055406	[79]	[66,65]	7	hSpCas9	negative selection	987308
52766240	52766263	3	+	26627737	GBM cells	viability after 13 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.09270930890024087	[586]	[253,334]	-1	hSpCas9	negative selection	987309
52768541	52768564	3	-	26627737	GBM cells	viability after 13 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.013134375185175018	[358]	[227,170]	0	hSpCas9	negative selection	987310
52770669	52770692	3	-	26627737	GBM cells	viability after 13 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-1.2530126932633079	[276]	[40,80]	-8	hSpCas9	negative selection	987311
52743424	52743447	3	-	26627737	GBM cells	viability after 21 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.24895864097178355	[164]	[76,73]	-2	hSpCas9	negative selection	1069621
52746796	52746819	3	+	26627737	GBM cells	viability after 21 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.9378604257150391	[312]	[354,298]	8	hSpCas9	negative selection	1069622
52751913	52751936	3	+	26627737	GBM cells	viability after 21 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	0.6675264473402897	[79]	[79,58]	6	hSpCas9	negative selection	1069623
52766240	52766263	3	+	26627737	GBM cells	viability after 21 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.17869400534023971	[586]	[361,359]	2	hSpCas9	negative selection	1069624
52768541	52768564	3	-	26627737	GBM cells	viability after 21 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.3881290158489621	[358]	[272,238]	4	hSpCas9	negative selection	1069625
52770669	52770692	3	-	26627737	GBM cells	viability after 21 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.8511490279323303	[276]	[96,70]	-6	hSpCas9	negative selection	1069626
52743424	52743447	3	-	26627737	RPE1	viability after 9 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.03646384087287779	[822]	[207,306]	0	hSpCas9	negative selection	1151936
52746796	52746819	3	+	26627737	RPE1	viability after 9 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.8296446717921272	[1220]	[643,724]	5	hSpCas9	negative selection	1151937
52751913	52751936	3	+	26627737	RPE1	viability after 9 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	0.6626739904511636	[154]	[78,73]	4	hSpCas9	negative selection	1151938
52766240	52766263	3	+	26627737	RPE1	viability after 9 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.486735499415597	[1920]	[864,813]	3	hSpCas9	negative selection	1151939
52768541	52768564	3	-	26627737	RPE1	viability after 9 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	-0.015712492294024605	[1321]	[449,356]	0	hSpCas9	negative selection	1151940
52770669	52770692	3	-	26627737	RPE1	viability after 9 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-1.4162425557183524	[897]	[179,8]	-7	hSpCas9	negative selection	1151941
52743424	52743447	3	-	26627737	RPE1	viability after 12 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	0.2006964636580537	[822]	[257,249]	1	hSpCas9	negative selection	1234251
52746796	52746819	3	+	26627737	RPE1	viability after 12 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.8180451310779927	[1220]	[453,709]	5	hSpCas9	negative selection	1234252
52751913	52751936	3	+	26627737	RPE1	viability after 12 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	0.922201593711985	[154]	[75,81]	6	hSpCas9	negative selection	1234253
52766240	52766263	3	+	26627737	RPE1	viability after 12 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.33473004792045313	[1920]	[748,546]	2	hSpCas9	negative selection	1234254
52768541	52768564	3	-	26627737	RPE1	viability after 12 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	-0.4740060997405395	[1321]	[245,265]	-3	hSpCas9	negative selection	1234255
52770669	52770692	3	-	26627737	RPE1	viability after 12 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-1.9086752942351588	[897]	[89,36]	-8	hSpCas9	negative selection	1234256
52743424	52743447	3	-	26627737	RPE1	viability after 15 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	0.2382807799489707	[822]	[267,280]	1	hSpCas9	negative selection	1316566
52746796	52746819	3	+	26627737	RPE1	viability after 15 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	1.1868432445856798	[1220]	[937,639]	6	hSpCas9	negative selection	1316567
52751913	52751936	3	+	26627737	RPE1	viability after 15 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	2.7091204687217587	[154]	[414,162]	9	hSpCas9	negative selection	1316568
52766240	52766263	3	+	26627737	RPE1	viability after 15 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.383799527142777	[1920]	[791,628]	2	hSpCas9	negative selection	1316569
52768541	52768564	3	-	26627737	RPE1	viability after 15 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.0660025219131175	[1321]	[589,199]	0	hSpCas9	negative selection	1316570
52770669	52770692	3	-	26627737	RPE1	viability after 15 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-1.4186236128198368	[897]	[149,41]	-7	hSpCas9	negative selection	1316571
52743424	52743447	3	-	26627737	RPE1	viability after 18 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	0.23248503503372311	[822]	[229,293]	1	hSpCas9	negative selection	1398881
52746796	52746819	3	+	26627737	RPE1	viability after 18 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	1.0078708902208984	[1220]	[709,611]	6	hSpCas9	negative selection	1398882
52751913	52751936	3	+	26627737	RPE1	viability after 18 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	1.4527775003317613	[154]	[99,129]	7	hSpCas9	negative selection	1398883
52766240	52766263	3	+	26627737	RPE1	viability after 18 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.4420698165032184	[1920]	[712,694]	3	hSpCas9	negative selection	1398884
52768541	52768564	3	-	26627737	RPE1	viability after 18 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	-0.8149176162916844	[1321]	[298,99]	-5	hSpCas9	negative selection	1398885
52770669	52770692	3	-	26627737	RPE1	viability after 18 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-1.752688740963195	[897]	[83,58]	-8	hSpCas9	negative selection	1398886
52743424	52743447	3	-	26627737	HeLa	viability after 8 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-1.1653328652393897	[442]	[262,9,27]	-8	hSpCas9	negative selection	1481196
52746796	52746819	3	+	26627737	HeLa	viability after 8 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.0020165855608899053	[701]	[381,343,214]	0	hSpCas9	negative selection	1481197
52751913	52751936	3	+	26627737	HeLa	viability after 8 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-2.129298166028741	[298]	[4,7,67]	-9	hSpCas9	negative selection	1481198
52766240	52766263	3	+	26627737	HeLa	viability after 8 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.65206942635949	[1475]	[537,476,250]	-6	hSpCas9	negative selection	1481199
52768541	52768564	3	-	26627737	HeLa	viability after 8 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.5266178326064996	[789]	[299,652,489]	5	hSpCas9	negative selection	1481200
52770669	52770692	3	-	26627737	HeLa	viability after 8 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-1.1359069187642692	[630]	[67,164,128]	-8	hSpCas9	negative selection	1481201
52743424	52743447	3	-	26627737	HeLa	viability after 12 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.18303132756366491	[442]	[149,108,229]	-2	hSpCas9	negative selection	1563511
52746796	52746819	3	+	26627737	HeLa	viability after 12 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.4783345421585141	[701]	[657,402,158]	4	hSpCas9	negative selection	1563512
52751913	52751936	3	+	26627737	HeLa	viability after 12 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-0.46147948092480856	[298]	[28,93,143]	-4	hSpCas9	negative selection	1563513
52766240	52766263	3	+	26627737	HeLa	viability after 12 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.439838951246291	[1475]	[444,297,621]	-4	hSpCas9	negative selection	1563514
52768541	52768564	3	-	26627737	HeLa	viability after 12 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.020026701906161737	[789]	[278,468,228]	0	hSpCas9	negative selection	1563515
52770669	52770692	3	-	26627737	HeLa	viability after 12 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-1.5955194761735525	[630]	[14,140,94]	-9	hSpCas9	negative selection	1563516
52743424	52743447	3	-	26627737	HeLa	viability after 15 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-1.0031724329942817	[442]	[139,90,33]	-7	hSpCas9	negative selection	1645826
52746796	52746819	3	+	26627737	HeLa	viability after 15 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.2638633326426305	[701]	[535,303,173]	2	hSpCas9	negative selection	1645827
52751913	52751936	3	+	26627737	HeLa	viability after 15 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-0.42798172248736505	[298]	[65,75,132]	-4	hSpCas9	negative selection	1645828
52766240	52766263	3	+	26627737	HeLa	viability after 15 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.47617293062859845	[1475]	[248,559,493]	-4	hSpCas9	negative selection	1645829
52768541	52768564	3	-	26627737	HeLa	viability after 15 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	-0.09698242674694202	[789]	[127,370,413]	-1	hSpCas9	negative selection	1645830
52770669	52770692	3	-	26627737	HeLa	viability after 15 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.9473749356161265	[630]	[164,139,90]	-7	hSpCas9	negative selection	1645831
52743424	52743447	3	-	26627737	HeLa	viability after 18 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.970697510696634	[442]	[94,78,33]	-7	hSpCas9	negative selection	1728141
52746796	52746819	3	+	26627737	HeLa	viability after 18 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.23457301173393796	[701]	[341,256,173]	2	hSpCas9	negative selection	1728142
52751913	52751936	3	+	26627737	HeLa	viability after 18 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-0.39738608681856796	[298]	[47,62,132]	-3	hSpCas9	negative selection	1728143
52766240	52766263	3	+	26627737	HeLa	viability after 18 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.45711419044675394	[1475]	[173,468,493]	-4	hSpCas9	negative selection	1728144
52768541	52768564	3	-	26627737	HeLa	viability after 18 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	-0.10599314133995874	[789]	[83,304,413]	-1	hSpCas9	negative selection	1728145
52770669	52770692	3	-	26627737	HeLa	viability after 18 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.9610724169907262	[630]	[104,119,90]	-7	hSpCas9	negative selection	1728146
52743424	52743447	3	-	26627737	HCT116	viability after 6 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	1.7830104193806038	[354]	[494,24]	8	hSpCas9	negative selection	1810456
52746796	52746819	3	+	26627737	HCT116	viability after 6 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	-0.31601693500618705	[772]	[134,76]	-2	hSpCas9	negative selection	1810457
52751913	52751936	3	+	26627737	HCT116	viability after 6 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-2.2309091519962068	[135]	[10,0]	-8	hSpCas9	negative selection	1810458
52766240	52766263	3	+	26627737	HCT116	viability after 6 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.33758579326753746	[1802]	[242,213]	-2	hSpCas9	negative selection	1810459
52768541	52768564	3	-	26627737	HCT116	viability after 6 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	1.095683603584788	[776]	[485,136]	6	hSpCas9	negative selection	1810460
52770669	52770692	3	-	26627737	HCT116	viability after 6 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-4.114720156496229	[1101]	[9,9]	-9	hSpCas9	negative selection	1810461
52743424	52743447	3	-	26627737	HCT116	viability after 8 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	0.048105024065295154	[162]	[125,127,25]	0	hSpCas9	negative selection	1892771
52746796	52746819	3	+	26627737	HCT116	viability after 8 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	-0.024346902205555243	[480]	[269,251,259]	0	hSpCas9	negative selection	1892772
52751913	52751936	3	+	26627737	HCT116	viability after 8 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-0.4923958863782685	[151]	[39,56,80]	-5	hSpCas9	negative selection	1892773
52766240	52766263	3	+	26627737	HCT116	viability after 8 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.08238255955083829	[768]	[531,332,481]	1	hSpCas9	negative selection	1892774
52768541	52768564	3	-	26627737	HCT116	viability after 8 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	-0.08638011967692671	[695]	[294,302,482]	-1	hSpCas9	negative selection	1892775
52770669	52770692	3	-	26627737	HCT116	viability after 8 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.3720802165915158	[218]	[150,206,110]	4	hSpCas9	negative selection	1892776
52743424	52743447	3	-	26627737	HCT116	viability after 9 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.03931406956866046	[354]	[170,29]	0	hSpCas9	negative selection	1975086
52746796	52746819	3	+	26627737	HCT116	viability after 9 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.2127822551568152	[772]	[303,187]	1	hSpCas9	negative selection	1975087
52751913	52751936	3	+	26627737	HCT116	viability after 9 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	2.5995954505498746	[135]	[199,235]	9	hSpCas9	negative selection	1975088
52766240	52766263	3	+	26627737	HCT116	viability after 9 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-1.1895404026784813	[1802]	[195,222]	-7	hSpCas9	negative selection	1975089
52768541	52768564	3	-	26627737	HCT116	viability after 9 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	1.30334594365781	[776]	[854,240]	8	hSpCas9	negative selection	1975090
52770669	52770692	3	-	26627737	HCT116	viability after 9 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-1.2457793461342725	[1101]	[108,135]	-7	hSpCas9	negative selection	1975091
52743424	52743447	3	-	26627737	HCT116	viability after 12 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	0.31851271158192274	[162]	[117,127,73]	3	hSpCas9	negative selection	2057401
52746796	52746819	3	+	26627737	HCT116	viability after 12 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.2928612771196306	[480]	[332,269,322]	3	hSpCas9	negative selection	2057402
52751913	52751936	3	+	26627737	HCT116	viability after 12 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-0.12244713997455592	[151]	[58,97,64]	-1	hSpCas9	negative selection	2057403
52766240	52766263	3	+	26627737	HCT116	viability after 12 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.19034709161289864	[768]	[544,542,289]	2	hSpCas9	negative selection	2057404
52768541	52768564	3	-	26627737	HCT116	viability after 12 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	-0.32558711699715837	[695]	[332,332,206]	-3	hSpCas9	negative selection	2057405
52770669	52770692	3	-	26627737	HCT116	viability after 12 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.5927731241037189	[218]	[183,222,113]	5	hSpCas9	negative selection	2057406
52743424	52743447	3	-	26627737	HCT116	viability after 15 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.15251845730990365	[162]	[78,86,85]	-1	hSpCas9	negative selection	2139716
52746796	52746819	3	+	26627737	HCT116	viability after 15 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.27945779747962196	[480]	[518,157,350]	2	hSpCas9	negative selection	2139717
52751913	52751936	3	+	26627737	HCT116	viability after 15 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-0.9713825499618627	[151]	[64,21,48]	-7	hSpCas9	negative selection	2139718
52766240	52766263	3	+	26627737	HCT116	viability after 15 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.4932307518503283	[768]	[644,703,519]	4	hSpCas9	negative selection	2139719
52768541	52768564	3	-	26627737	HCT116	viability after 15 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.32822722417841943	[695]	[547,453,508]	3	hSpCas9	negative selection	2139720
52770669	52770692	3	-	26627737	HCT116	viability after 15 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.636484356771032	[218]	[243,281,67]	6	hSpCas9	negative selection	2139721
52743424	52743447	3	-	26627737	HCT116	viability after 18 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.20273954624575863	[162]	[133,27,44]	-2	hSpCas9	negative selection	2222031
52746796	52746819	3	+	26627737	HCT116	viability after 18 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.4661937562360665	[480]	[395,176,403]	4	hSpCas9	negative selection	2222032
52751913	52751936	3	+	26627737	HCT116	viability after 18 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	0.1967514935527731	[151]	[131,95,20]	1	hSpCas9	negative selection	2222033
52766240	52766263	3	+	26627737	HCT116	viability after 18 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.8269139457582637	[768]	[641,584,760]	6	hSpCas9	negative selection	2222034
52768541	52768564	3	-	26627737	HCT116	viability after 18 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.6782191908373651	[695]	[452,652,499]	5	hSpCas9	negative selection	2222035
52770669	52770692	3	-	26627737	HCT116	viability after 18 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.5055234839536096	[218]	[173,156,117]	4	hSpCas9	negative selection	2222036
52766267	52766290	3	+	24336569	HL60	viability	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	0.9185358993711038	[360]	[1443]	7	hSpCas9	negative selection	2279787
52766292	52766315	3	-	24336569	HL60	viability	GAACAAACATCATCAAAGTAGGG	NEK4	ENSG00000114904	-0.1696740574311879	[1508]	[2838]	-1	hSpCas9	negative selection	2279788
52766300	52766323	3	+	24336569	HL60	viability	TGATGATGTTTGTTCTTGTTAGG	NEK4	ENSG00000114904	0.48882182345981606	[493]	[1466]	4	hSpCas9	negative selection	2279789
52770650	52770673	3	+	24336569	HL60	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.07727630366546273	[687]	[1379]	0	hSpCas9	negative selection	2279790
52770661	52770684	3	-	24336569	HL60	viability	CTTGTGAAGCACCGGCGGGACGG	NEK4	ENSG00000114904	0.5274702728018028	[377]	[1152]	5	hSpCas9	negative selection	2279791
52770666	52770689	3	-	24336569	HL60	viability	TGACGCTTGTGAAGCACCGGCGG	NEK4	ENSG00000114904	-0.6875063194688805	[292]	[384]	-6	hSpCas9	negative selection	2279792
52770703	52770726	3	-	24336569	HL60	viability	TACCTGCGGGTCGTGGGCAAGGG	NEK4	ENSG00000114904	-0.9147558118701269	[448]	[503]	-7	hSpCas9	negative selection	2279793
52770709	52770732	3	-	24336569	HL60	viability	TACTGCTACCTGCGGGTCGTGGG	NEK4	ENSG00000114904	1.0242391957533352	[637]	[2745]	7	hSpCas9	negative selection	2279794
52770714	52770737	3	+	24336569	HL60	viability	GACCCGCAGGTAGCAGTAGGCGG	NEK4	ENSG00000114904	0.5341951973151762	[681]	[2089]	5	hSpCas9	negative selection	2279795
52770719	52770742	3	+	24336569	HL60	viability	GCAGGTAGCAGTAGGCGGCCAGG	NEK4	ENSG00000114904	0.7867831422383372	[337]	[1233]	6	hSpCas9	negative selection	2279796
52766267	52766290	3	+	24336569	KBM7	viability	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	0.6127934214305993	[233]	[975]	5	hSpCas9	negative selection	2346964
52766292	52766315	3	-	24336569	KBM7	viability	GAACAAACATCATCAAAGTAGGG	NEK4	ENSG00000114904	0.38651557346114274	[1007]	[3593]	3	hSpCas9	negative selection	2346965
52766300	52766323	3	+	24336569	KBM7	viability	TGATGATGTTTGTTCTTGTTAGG	NEK4	ENSG00000114904	0.7626385108414631	[407]	[1887]	6	hSpCas9	negative selection	2346966
52770650	52770673	3	+	24336569	KBM7	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.2419966806822057	[686]	[2215]	2	hSpCas9	negative selection	2346967
52770661	52770684	3	-	24336569	KBM7	viability	CTTGTGAAGCACCGGCGGGACGG	NEK4	ENSG00000114904	0.608582484306625	[295]	[1230]	5	hSpCas9	negative selection	2346968
52770666	52770689	3	-	24336569	KBM7	viability	TGACGCTTGTGAAGCACCGGCGG	NEK4	ENSG00000114904	0.25248171233681316	[292]	[951]	2	hSpCas9	negative selection	2346969
52770703	52770726	3	-	24336569	KBM7	viability	TACCTGCGGGTCGTGGGCAAGGG	NEK4	ENSG00000114904	0.06653297770181682	[312]	[893]	0	hSpCas9	negative selection	2346970
52770709	52770732	3	-	24336569	KBM7	viability	TACTGCTACCTGCGGGTCGTGGG	NEK4	ENSG00000114904	-0.302275680610645	[1089]	[2410]	-3	hSpCas9	negative selection	2346971
52770714	52770737	3	+	24336569	KBM7	viability	GACCCGCAGGTAGCAGTAGGCGG	NEK4	ENSG00000114904	0.6616971730210448	[555]	[2398]	6	hSpCas9	negative selection	2346972
52770719	52770742	3	+	24336569	KBM7	viability	GCAGGTAGCAGTAGGCGGCCAGG	NEK4	ENSG00000114904	0.5295657505706305	[508]	[2003]	5	hSpCas9	negative selection	2346973
52737028	52737051	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATTGTTTGAACCTAG	NEK4	ENSG00000114904	0.964443282063522	[91,283]	[89,70]	4	dCas9-VP64	positive selection	2426639
52745819	52745842	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTCAAGCCATCCTCCCACCTCGG	NEK4	ENSG00000114904	-1.0550787617713646	[224,291]	[11,42]	-6	dCas9-VP64	positive selection	2436414
52734097	52734120	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCCCAGCACTTGAG	NEK4	ENSG00000114904	-0.7697329427055237	[305,492]	[31,71]	-4	dCas9-VP64	positive selection	2453159
52752823	52752846	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCCGCCTCCTAG	NEK4	ENSG00000114904	-1.3762222380081446	[352,174]	[18,24]	-7	dCas9-VP64	positive selection	2454213
52744598	52744621	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTTGAACCTGGGAGGCGGTGG	NEK4	ENSG00000114904	-0.49448069816640183	[10,25]	[2,1]	-2	dCas9-VP64	positive selection	2460710
52736540	52736563	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCACCACTGCACTCCAGCCTAG	NEK4	ENSG00000114904	3.0347564003538725	[8,6]	[27,0]	8	dCas9-VP64	positive selection	2470759
52737028	52737051	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATTGTTTGAACCTAG	NEK4	ENSG00000114904	-0.320288383300443	[193,176]	[58,37]	-3	dCas9-VP64	positive selection	2521894
52745819	52745842	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTCAAGCCATCCTCCCACCTCGG	NEK4	ENSG00000114904	0.12096276410502044	[78,167]	[40,44]	1	dCas9-VP64	positive selection	2531669
52734097	52734120	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCCCAGCACTTGAG	NEK4	ENSG00000114904	-0.7960951384238878	[400,199]	[64,47]	-7	dCas9-VP64	positive selection	2548414
52752823	52752846	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCCGCCTCCTAG	NEK4	ENSG00000114904	-1.0610924962734893	[123,419]	[26,55]	-8	dCas9-VP64	positive selection	2549468
52744598	52744621	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTTGAACCTGGGAGGCGGTGG	NEK4	ENSG00000114904	-1.2686416065166946	[152,79]	[23,7]	-9	dCas9-VP64	positive selection	2555965
52736540	52736563	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCACCACTGCACTCCAGCCTAG	NEK4	ENSG00000114904	0.038175304513698105	[60,77]	[26,18]	0	dCas9-VP64	positive selection	2566014
52766292	52766315	3	-	27260157	DLD1	viability	GAACAAACATCATCAAAGTAGGG	NEK4	ENSG00000114904	1.31319118251944	[]	[]	9	hSpCas9	negative selection	2578912
52770703	52770726	3	-	27260157	DLD1	viability	TACCTGCGGGTCGTGGGCAAGGG	NEK4	ENSG00000114904	-1.53815635206799	[]	[]	-8	hSpCas9	negative selection	2579283
52768514	52768537	3	+	27260157	DLD1	viability	GCTTCAACTGAGACAAGAGCTGG	NEK4	ENSG00000114904	0.46623215539122	[]	[]	8	hSpCas9	negative selection	2579709
52770661	52770684	3	-	27260157	DLD1	viability	CTTGTGAAGCACCGGCGGGACGG	NEK4	ENSG00000114904	-0.211510270674646	[]	[]	-1	hSpCas9	negative selection	2585916
52770721	52770744	3	+	27260157	DLD1	viability	AGGTAGCAGTAGGCGGCCAGGGG	NEK4	ENSG00000114904	0.113269431852782	[]	[]	3	hSpCas9	negative selection	2604289
52768557	52768580	3	-	27260157	DLD1	viability	GAAATGCCTCTAGCCGAGAGCGG	NEK4	ENSG00000114904	0.146117923743939	[]	[]	3	hSpCas9	negative selection	2605006
52770650	52770673	3	+	27260157	DLD1	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.198113410886744	[]	[]	-1	hSpCas9	negative selection	2605407
52768488	52768511	3	+	27260157	DLD1	viability	CTCCTTGTAGGTGACAATGTTGG	NEK4	ENSG00000114904	-0.167875415555252	[]	[]	-1	hSpCas9	negative selection	2608068
52766300	52766323	3	+	27260157	DLD1	viability	TGATGATGTTTGTTCTTGTTAGG	NEK4	ENSG00000114904	0.30043594212997	[]	[]	4	hSpCas9	negative selection	2608509
52770714	52770737	3	+	27260157	DLD1	viability	GACCCGCAGGTAGCAGTAGGCGG	NEK4	ENSG00000114904	-0.07381249928211	[]	[]	0	hSpCas9	negative selection	2610426
52770709	52770732	3	-	27260157	DLD1	viability	TACTGCTACCTGCGGGTCGTGGG	NEK4	ENSG00000114904	-1.22440005096101	[]	[]	-7	hSpCas9	negative selection	2611681
52770666	52770689	3	-	27260157	DLD1	viability	TGACGCTTGTGAAGCACCGGCGG	NEK4	ENSG00000114904	0.283679388148295	[]	[]	4	hSpCas9	negative selection	2614605
52766267	52766290	3	+	27260157	DLD1	viability	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	-0.895118144921597	[]	[]	-6	hSpCas9	negative selection	2619375
52768559	52768582	3	+	27260157	DLD1	viability	GCTCTCGGCTAGAGGCATTTCGG	NEK4	ENSG00000114904	-0.645937972194908	[]	[]	-5	hSpCas9	negative selection	2644437
52770702	52770725	3	-	27260157	DLD1	viability	ACCTGCGGGTCGTGGGCAAGGGG	NEK4	ENSG00000114904	-0.618648153894795	[]	[]	-5	hSpCas9	negative selection	2646554
52770711	52770734	3	+	27260157	DLD1	viability	CACGACCCGCAGGTAGCAGTAGG	NEK4	ENSG00000114904	-0.267386353024678	[]	[]	-2	hSpCas9	negative selection	2647803
52766292	52766315	3	-	27260157	HT1080	viability	GAACAAACATCATCAAAGTAGGG	NEK4	ENSG00000114904	-0.377007219964668	[]	[]	-7	hSpCas9	negative selection	2655042
52770703	52770726	3	-	27260157	HT1080	viability	TACCTGCGGGTCGTGGGCAAGGG	NEK4	ENSG00000114904	-1.47130726145865	[]	[]	-9	hSpCas9	negative selection	2655413
52768514	52768537	3	+	27260157	HT1080	viability	GCTTCAACTGAGACAAGAGCTGG	NEK4	ENSG00000114904	1.05309936377221	[]	[]	8	hSpCas9	negative selection	2655839
52770661	52770684	3	-	27260157	HT1080	viability	CTTGTGAAGCACCGGCGGGACGG	NEK4	ENSG00000114904	-0.252543852777224	[]	[]	0	hSpCas9	negative selection	2662046
52770721	52770744	3	+	27260157	HT1080	viability	AGGTAGCAGTAGGCGGCCAGGGG	NEK4	ENSG00000114904	0.852278144468926	[]	[]	7	hSpCas9	negative selection	2680419
52768557	52768580	3	-	27260157	HT1080	viability	GAAATGCCTCTAGCCGAGAGCGG	NEK4	ENSG00000114904	0.126677527976661	[]	[]	1	hSpCas9	negative selection	2681136
52770650	52770673	3	+	27260157	HT1080	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.29373538139151	[]	[]	2	hSpCas9	negative selection	2681537
52768488	52768511	3	+	27260157	HT1080	viability	CTCCTTGTAGGTGACAATGTTGG	NEK4	ENSG00000114904	-0.789629723075225	[]	[]	-8	hSpCas9	negative selection	2684198
52766300	52766323	3	+	27260157	HT1080	viability	TGATGATGTTTGTTCTTGTTAGG	NEK4	ENSG00000114904	0.0512442228380892	[]	[]	0	hSpCas9	negative selection	2684639
52770714	52770737	3	+	27260157	HT1080	viability	GACCCGCAGGTAGCAGTAGGCGG	NEK4	ENSG00000114904	0.13290023608457	[]	[]	1	hSpCas9	negative selection	2686556
52770709	52770732	3	-	27260157	HT1080	viability	TACTGCTACCTGCGGGTCGTGGG	NEK4	ENSG00000114904	-1.77098693318614	[]	[]	-9	hSpCas9	negative selection	2687811
52770666	52770689	3	-	27260157	HT1080	viability	TGACGCTTGTGAAGCACCGGCGG	NEK4	ENSG00000114904	-0.19552137440033	[]	[]	0	hSpCas9	negative selection	2690735
52766267	52766290	3	+	27260157	HT1080	viability	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	0.0338339608688104	[]	[]	0	hSpCas9	negative selection	2695505
52768559	52768582	3	+	27260157	HT1080	viability	GCTCTCGGCTAGAGGCATTTCGG	NEK4	ENSG00000114904	-0.747481181531513	[]	[]	-8	hSpCas9	negative selection	2720567
52770702	52770725	3	-	27260157	HT1080	viability	ACCTGCGGGTCGTGGGCAAGGGG	NEK4	ENSG00000114904	-1.59567978238265	[]	[]	-9	hSpCas9	negative selection	2722684
52770711	52770734	3	+	27260157	HT1080	viability	CACGACCCGCAGGTAGCAGTAGG	NEK4	ENSG00000114904	-0.223519809189532	[]	[]	0	hSpCas9	negative selection	2723933
52766292	52766315	3	-	27260157	MKN45	viability	GAACAAACATCATCAAAGTAGGG	NEK4	ENSG00000114904	0.878638156442294	[]	[]	8	hSpCas9	negative selection	2731172
52770703	52770726	3	-	27260157	MKN45	viability	TACCTGCGGGTCGTGGGCAAGGG	NEK4	ENSG00000114904	-1.88214816564373	[]	[]	-9	hSpCas9	negative selection	2731543
52768514	52768537	3	+	27260157	MKN45	viability	GCTTCAACTGAGACAAGAGCTGG	NEK4	ENSG00000114904	0.478792097359572	[]	[]	6	hSpCas9	negative selection	2731969
52770661	52770684	3	-	27260157	MKN45	viability	CTTGTGAAGCACCGGCGGGACGG	NEK4	ENSG00000114904	-0.271874791804035	[]	[]	-1	hSpCas9	negative selection	2738176
52770721	52770744	3	+	27260157	MKN45	viability	AGGTAGCAGTAGGCGGCCAGGGG	NEK4	ENSG00000114904	-0.696507875280464	[]	[]	-7	hSpCas9	negative selection	2756549
52768557	52768580	3	-	27260157	MKN45	viability	GAAATGCCTCTAGCCGAGAGCGG	NEK4	ENSG00000114904	0.529201944534245	[]	[]	6	hSpCas9	negative selection	2757266
52770650	52770673	3	+	27260157	MKN45	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.212860569923161	[]	[]	-1	hSpCas9	negative selection	2757667
52768488	52768511	3	+	27260157	MKN45	viability	CTCCTTGTAGGTGACAATGTTGG	NEK4	ENSG00000114904	-0.627240192004261	[]	[]	-6	hSpCas9	negative selection	2760328
52766300	52766323	3	+	27260157	MKN45	viability	TGATGATGTTTGTTCTTGTTAGG	NEK4	ENSG00000114904	0.030928519025548	[]	[]	0	hSpCas9	negative selection	2760769
52770714	52770737	3	+	27260157	MKN45	viability	GACCCGCAGGTAGCAGTAGGCGG	NEK4	ENSG00000114904	-0.0739683764374445	[]	[]	0	hSpCas9	negative selection	2762686
52770709	52770732	3	-	27260157	MKN45	viability	TACTGCTACCTGCGGGTCGTGGG	NEK4	ENSG00000114904	-0.293493807281509	[]	[]	-1	hSpCas9	negative selection	2763941
52770666	52770689	3	-	27260157	MKN45	viability	TGACGCTTGTGAAGCACCGGCGG	NEK4	ENSG00000114904	-1.16159179387446	[]	[]	-8	hSpCas9	negative selection	2766865
52766267	52766290	3	+	27260157	MKN45	viability	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	-0.864616813143843	[]	[]	-7	hSpCas9	negative selection	2771635
52768559	52768582	3	+	27260157	MKN45	viability	GCTCTCGGCTAGAGGCATTTCGG	NEK4	ENSG00000114904	-0.350045072784238	[]	[]	-1	hSpCas9	negative selection	2796697
52770702	52770725	3	-	27260157	MKN45	viability	ACCTGCGGGTCGTGGGCAAGGGG	NEK4	ENSG00000114904	-2.52707124413236	[]	[]	-9	hSpCas9	negative selection	2798814
52770711	52770734	3	+	27260157	MKN45	viability	CACGACCCGCAGGTAGCAGTAGG	NEK4	ENSG00000114904	-0.907319565332885	[]	[]	-7	hSpCas9	negative selection	2800063
52766292	52766315	3	-	27260157	RKO	viability	GAACAAACATCATCAAAGTAGGG	NEK4	ENSG00000114904	0.501920444795259	[]	[]	2	hSpCas9	negative selection	2807302
52770703	52770726	3	-	27260157	RKO	viability	TACCTGCGGGTCGTGGGCAAGGG	NEK4	ENSG00000114904	-1.22095116449048	[]	[]	-8	hSpCas9	negative selection	2807673
52768514	52768537	3	+	27260157	RKO	viability	GCTTCAACTGAGACAAGAGCTGG	NEK4	ENSG00000114904	0.318638746559529	[]	[]	1	hSpCas9	negative selection	2808099
52770661	52770684	3	-	27260157	RKO	viability	CTTGTGAAGCACCGGCGGGACGG	NEK4	ENSG00000114904	-0.511313306682803	[]	[]	-6	hSpCas9	negative selection	2814306
52770721	52770744	3	+	27260157	RKO	viability	AGGTAGCAGTAGGCGGCCAGGGG	NEK4	ENSG00000114904	0.902517996223364	[]	[]	8	hSpCas9	negative selection	2832679
52768557	52768580	3	-	27260157	RKO	viability	GAAATGCCTCTAGCCGAGAGCGG	NEK4	ENSG00000114904	1.13490449869736	[]	[]	9	hSpCas9	negative selection	2833396
52770650	52770673	3	+	27260157	RKO	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.553261368228295	[]	[]	3	hSpCas9	negative selection	2833797
52768488	52768511	3	+	27260157	RKO	viability	CTCCTTGTAGGTGACAATGTTGG	NEK4	ENSG00000114904	-0.729083337453066	[]	[]	-7	hSpCas9	negative selection	2836458
52766300	52766323	3	+	27260157	RKO	viability	TGATGATGTTTGTTCTTGTTAGG	NEK4	ENSG00000114904	0.0336267910976718	[]	[]	0	hSpCas9	negative selection	2836899
52770714	52770737	3	+	27260157	RKO	viability	GACCCGCAGGTAGCAGTAGGCGG	NEK4	ENSG00000114904	0.152406882682426	[]	[]	0	hSpCas9	negative selection	2838816
52770709	52770732	3	-	27260157	RKO	viability	TACTGCTACCTGCGGGTCGTGGG	NEK4	ENSG00000114904	-0.81912150867574	[]	[]	-7	hSpCas9	negative selection	2840071
52770666	52770689	3	-	27260157	RKO	viability	TGACGCTTGTGAAGCACCGGCGG	NEK4	ENSG00000114904	-0.657118447920695	[]	[]	-7	hSpCas9	negative selection	2842995
52766267	52766290	3	+	27260157	RKO	viability	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	-0.684704261319105	[]	[]	-7	hSpCas9	negative selection	2847765
52768559	52768582	3	+	27260157	RKO	viability	GCTCTCGGCTAGAGGCATTTCGG	NEK4	ENSG00000114904	-0.237145736230211	[]	[]	-1	hSpCas9	negative selection	2872827
52770702	52770725	3	-	27260157	RKO	viability	ACCTGCGGGTCGTGGGCAAGGGG	NEK4	ENSG00000114904	-0.934616371463166	[]	[]	-8	hSpCas9	negative selection	2874944
52770711	52770734	3	+	27260157	RKO	viability	CACGACCCGCAGGTAGCAGTAGG	NEK4	ENSG00000114904	-0.228601540424107	[]	[]	-1	hSpCas9	negative selection	2876193
52766292	52766315	3	-	27260157	SF268	viability	GAACAAACATCATCAAAGTAGGG	NEK4	ENSG00000114904	0.532114845809749	[]	[]	8	hSpCas9	negative selection	2883432
52770703	52770726	3	-	27260157	SF268	viability	TACCTGCGGGTCGTGGGCAAGGG	NEK4	ENSG00000114904	-0.0996839016952505	[]	[]	-1	hSpCas9	negative selection	2883803
52768514	52768537	3	+	27260157	SF268	viability	GCTTCAACTGAGACAAGAGCTGG	NEK4	ENSG00000114904	0.96970982876053	[]	[]	9	hSpCas9	negative selection	2884229
52770661	52770684	3	-	27260157	SF268	viability	CTTGTGAAGCACCGGCGGGACGG	NEK4	ENSG00000114904	0.486421534217201	[]	[]	7	hSpCas9	negative selection	2890436
52770721	52770744	3	+	27260157	SF268	viability	AGGTAGCAGTAGGCGGCCAGGGG	NEK4	ENSG00000114904	0.0744932220172674	[]	[]	0	hSpCas9	negative selection	2908809
52768557	52768580	3	-	27260157	SF268	viability	GAAATGCCTCTAGCCGAGAGCGG	NEK4	ENSG00000114904	1.02236170030931	[]	[]	9	hSpCas9	negative selection	2909526
52770650	52770673	3	+	27260157	SF268	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.105516798154733	[]	[]	0	hSpCas9	negative selection	2909927
52768488	52768511	3	+	27260157	SF268	viability	CTCCTTGTAGGTGACAATGTTGG	NEK4	ENSG00000114904	-1.03564102282146	[]	[]	-7	hSpCas9	negative selection	2912588
52766300	52766323	3	+	27260157	SF268	viability	TGATGATGTTTGTTCTTGTTAGG	NEK4	ENSG00000114904	0.346473115161661	[]	[]	4	hSpCas9	negative selection	2913029
52770714	52770737	3	+	27260157	SF268	viability	GACCCGCAGGTAGCAGTAGGCGG	NEK4	ENSG00000114904	0.169718690593921	[]	[]	0	hSpCas9	negative selection	2914946
52770709	52770732	3	-	27260157	SF268	viability	TACTGCTACCTGCGGGTCGTGGG	NEK4	ENSG00000114904	-1.25779361397646	[]	[]	-7	hSpCas9	negative selection	2916201
52770666	52770689	3	-	27260157	SF268	viability	TGACGCTTGTGAAGCACCGGCGG	NEK4	ENSG00000114904	-0.0987502185175861	[]	[]	-1	hSpCas9	negative selection	2919125
52766267	52766290	3	+	27260157	SF268	viability	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	-0.433634026834071	[]	[]	-3	hSpCas9	negative selection	2923895
52768559	52768582	3	+	27260157	SF268	viability	GCTCTCGGCTAGAGGCATTTCGG	NEK4	ENSG00000114904	-0.912836305128051	[]	[]	-6	hSpCas9	negative selection	2948957
52770702	52770725	3	-	27260157	SF268	viability	ACCTGCGGGTCGTGGGCAAGGGG	NEK4	ENSG00000114904	-0.42435920201344	[]	[]	-3	hSpCas9	negative selection	2951074
52770711	52770734	3	+	27260157	SF268	viability	CACGACCCGCAGGTAGCAGTAGG	NEK4	ENSG00000114904	-0.0234403552625405	[]	[]	0	hSpCas9	negative selection	2952323
52751913	52751936	3	+	27013184	SW480	treatment with recombinant TRAIL	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-0.468473188884194	[629,534]	[241,98]	-2	hSpCas9	positive selection	2958004
52751921	52751944	3	+	27013184	SW480	treatment with recombinant TRAIL	ATATCACTCACCTGGTCCTTTGG	NEK4	ENSG00000114904	0.39938906418036313	[152,199]	[57,157]	2	hSpCas9	positive selection	2958005
52766333	52766356	3	+	27013184	SW480	treatment with recombinant TRAIL	GAGTTTTCAGATCTCGATGAAGG	NEK4	ENSG00000114904	-0.07748189413762008	[16,16]	[1,13]	0	hSpCas9	positive selection	2958006
52751951	52751974	3	+	27013184	SW480	treatment with recombinant TRAIL	TCTTTGATTAGGGGCTGCAGAGG	NEK4	ENSG00000114904	0.08293031930140093	[106,156]	[48,73]	0	hSpCas9	positive selection	2958007
52766169	52766192	3	+	27013184	SW480	treatment with recombinant TRAIL	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	1.6679322767801898	[9,1]	[4,13]	7	hSpCas9	positive selection	2958008
52770701	52770724	3	+	27013184	SW480	treatment with recombinant TRAIL	TCCCCTTGCCCACGACCCGCAGG	NEK4	ENSG00000114904	0.7426239788973943	[756,1246]	[727,678]	3	hSpCas9	positive selection	2958009
52770738	52770761	3	+	27013184	SW480	treatment with recombinant TRAIL	CAGGGGCATGTTCCCAGCGCTGG	NEK4	ENSG00000114904	-0.15628234676408106	[280,236]	[53,167]	0	hSpCas9	positive selection	2958010
52751960	52751983	3	+	27013184	SW480	treatment with recombinant TRAIL	AGGGGCTGCAGAGGCTTCACTGG	NEK4	ENSG00000114904	1.4125803681660463	[225,354]	[289,379]	6	hSpCas9	positive selection	2958013
52766170	52766193	3	+	27013184	SW480	treatment with recombinant TRAIL	AATCCTACCTTATAGTTGTAGGG	NEK4	ENSG00000114904	-0.8995197254434414	[343,355]	[46,128]	-4	hSpCas9	positive selection	2958014
52751992	52752015	3	+	27013184	SW480	treatment with recombinant TRAIL	TTCCCCAGTGACAATGTCAGAGG	NEK4	ENSG00000114904	1.2013790831237363	[465,922]	[777,513]	5	hSpCas9	positive selection	2958015
52766205	52766228	3	+	27013184	SW480	treatment with recombinant TRAIL	CAATTCAGGGCTCATGTAGTAGG	NEK4	ENSG00000114904	1.5912063823366966	[520,378]	[440,809]	7	hSpCas9	positive selection	2958016
52766168	52766191	3	-	27013184	SW480	treatment with recombinant TRAIL	CTACAACTATAAGGTAGGATTGG	NEK4	ENSG00000114904	1.0370663638516657	[436,414]	[257,548]	5	hSpCas9	positive selection	2958017
52766173	52766196	3	-	27013184	SW480	treatment with recombinant TRAIL	AAACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	-2.5849801577017923	[346,513]	[22,40]	-8	hSpCas9	positive selection	2958018
52766233	52766256	3	-	27013184	SW480	treatment with recombinant TRAIL	GACATGGCTAGCACCCTCATTGG	NEK4	ENSG00000114904	-0.6790534340831509	[1591,2110]	[394,631]	-3	hSpCas9	positive selection	2958019
52766284	52766307	3	-	27013184	SW480	treatment with recombinant TRAIL	ATCATCAAAGTAGGGGACCTAGG	NEK4	ENSG00000114904	-2.080323516032974	[147,181]	[26,1]	-7	hSpCas9	positive selection	2958020
52766291	52766314	3	-	27013184	SW480	treatment with recombinant TRAIL	AACAAACATCATCAAAGTAGGGG	NEK4	ENSG00000114904	1.2124738110114626	[1,1]	[1,1]	6	hSpCas9	positive selection	2958021
52766292	52766315	3	-	27013184	SW480	treatment with recombinant TRAIL	GAACAAACATCATCAAAGTAGGG	NEK4	ENSG00000114904	1.2124738110114626	[1,1]	[1,1]	6	hSpCas9	positive selection	2958022
52752001	52752024	3	+	27013184	SW480	treatment with recombinant TRAIL	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	1.3404776844319393	[84,109]	[9,240]	6	hSpCas9	positive selection	2958023
52766206	52766229	3	+	27013184	SW480	treatment with recombinant TRAIL	AATTCAGGGCTCATGTAGTAGGG	NEK4	ENSG00000114904	0.3342424530962864	[685,784]	[119,792]	1	hSpCas9	positive selection	2958024
52766293	52766316	3	-	27013184	SW480	treatment with recombinant TRAIL	AGAACAAACATCATCAAAGTAGG	NEK4	ENSG00000114904	3.5613140820952247	[4,1]	[1,41]	9	hSpCas9	positive selection	2958025
52752002	52752025	3	+	27013184	SW480	treatment with recombinant TRAIL	ACAATGTCAGAGGACCACATGGG	NEK4	ENSG00000114904	-2.5241208516139864	[301,599]	[24,43]	-8	hSpCas9	positive selection	2958026
52766240	52766263	3	+	27013184	SW480	treatment with recombinant TRAIL	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.18197574918275	[114,236]	[40,143]	0	hSpCas9	positive selection	2958027
52752017	52752040	3	+	27013184	SW480	treatment with recombinant TRAIL	CACATGGGAATCAGGTTTTCAGG	NEK4	ENSG00000114904	1.2014192317758097	[261,451]	[335,359]	5	hSpCas9	positive selection	2958028
52766255	52766278	3	+	27013184	SW480	treatment with recombinant TRAIL	CACAGTGGTTCTCTAACACTCGG	NEK4	ENSG00000114904	1.0346898588947757	[153,94]	[21,240]	5	hSpCas9	positive selection	2958029
52751994	52752017	3	-	27013184	SW480	treatment with recombinant TRAIL	GTCCTCTGACATTGTCACTGGGG	NEK4	ENSG00000114904	0.37572489422892424	[299,212]	[165,116]	2	hSpCas9	positive selection	2958030
52751995	52752018	3	-	27013184	SW480	treatment with recombinant TRAIL	GGTCCTCTGACATTGTCACTGGG	NEK4	ENSG00000114904	0.620862886469926	[217,198]	[147,125]	3	hSpCas9	positive selection	2958031
52751996	52752019	3	-	27013184	SW480	treatment with recombinant TRAIL	TGGTCCTCTGACATTGTCACTGG	NEK4	ENSG00000114904	-1.3582567862611898	[548,949]	[130,111]	-6	hSpCas9	positive selection	2958032
52752016	52752039	3	-	27013184	SW480	treatment with recombinant TRAIL	CTGAAAACCTGATTCCCATGTGG	NEK4	ENSG00000114904	2.251878171795474	[32,66]	[142,37]	8	hSpCas9	positive selection	2958033
52752021	52752044	3	+	27013184	SW480	treatment with recombinant TRAIL	TGGGAATCAGGTTTTCAGGCTGG	NEK4	ENSG00000114904	3.3375173350404737	[38,10]	[111,117]	9	hSpCas9	positive selection	2958034
52766267	52766290	3	+	27013184	SW480	treatment with recombinant TRAIL	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	1.3884835468126595	[48,28]	[16,84]	6	hSpCas9	positive selection	2958035
52766268	52766291	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	-0.34471623486065855	[3,3]	[2,2]	-5	hSpCas9	positive selection	3005246
52770665	52770688	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.7176501833263891	[1,1]	[0,4]	9	hSpCas9	positive selection	3005247
52763502	52763525	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGGCAGCCTTATATAAAGCGG	NEK4	ENSG00000114904	0.09499671542265477	[3,3]	[3,3]	2	hSpCas9	positive selection	3005248
52752300	52752323	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTGTCCCAGGAGAAACCCAGGG	NEK4	ENSG00000114904	0.2205380258988668	[2,2]	[2,3]	5	hSpCas9	positive selection	3005249
52766268	52766291	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	0.29694881435776554	[3,3]	[3,2]	5	hSpCas9	positive selection	3073104
52770665	52770688	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.46535628922233585	[1,1]	[2,1]	7	hSpCas9	positive selection	3073105
52763502	52763525	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGGCAGCCTTATATAAAGCGG	NEK4	ENSG00000114904	0.2356936100145434	[3,3]	[4,2]	4	hSpCas9	positive selection	3073106
52752300	52752323	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTGTCCCAGGAGAAACCCAGGG	NEK4	ENSG00000114904	0.5361945854017741	[2,2]	[2,2]	8	hSpCas9	positive selection	3073107
52770650	52770673		+	24336571	A375	resistance to PLX after 7 days	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.009055085921055639	[47,39]	[40,46]	0	hSpCas9	positive selection	3130309
52770669	52770692		-	24336571	A375	resistance to PLX after 7 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.08838172851359016	[33,34]	[34,36]	3	hSpCas9	positive selection	3130310
52766169	52766192		+	24336571	A375	resistance to PLX after 7 days	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	-0.028723511942797764	[53,55]	[55,50]	-1	hSpCas9	positive selection	3130311
52766255	52766278		+	24336571	A375	resistance to PLX after 7 days	CACAGTGGTTCTCTAACACTCGG	NEK4	ENSG00000114904	-0.07859774617778537	[23,20]	[22,18]	-2	hSpCas9	positive selection	3130313
52766333	52766356		+	24336571	A375	resistance to PLX after 7 days	GAGTTTTCAGATCTCGATGAAGG	NEK4	ENSG00000114904	0.08755570687761605	[4,4]	[5,4]	3	hSpCas9	positive selection	3130314
52770717	52770740		-	24336571	A375	resistance to PLX after 7 days	TGGCCGCCTACTGCTACCTGCGG	NEK4	ENSG00000114904	-0.2675001058756037	[18,13]	[13,12]	-7	hSpCas9	positive selection	3130315
52770650	52770673		+	24336571	A375	resistance to PLX after 14 days	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.0956391884530916	[55,36]	[19,19]	-1	hSpCas9	positive selection	3188102
52770669	52770692		-	24336571	A375	resistance to PLX after 14 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.333326517851543	[30,32]	[15,20]	3	hSpCas9	positive selection	3188103
52766169	52766192		+	24336571	A375	resistance to PLX after 14 days	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.03610946813466276	[60,60]	[27,29]	0	hSpCas9	positive selection	3188104
52766255	52766278		+	24336571	A375	resistance to PLX after 14 days	CACAGTGGTTCTCTAACACTCGG	NEK4	ENSG00000114904	-0.2517374663924671	[23,25]	[9,8]	-3	hSpCas9	positive selection	3188106
52766333	52766356		+	24336571	A375	resistance to PLX after 14 days	GAGTTTTCAGATCTCGATGAAGG	NEK4	ENSG00000114904	0.37936248090920466	[7,4]	[2,4]	3	hSpCas9	positive selection	3188107
52770717	52770740		-	24336571	A375	resistance to PLX after 14 days	TGGCCGCCTACTGCTACCTGCGG	NEK4	ENSG00000114904	-0.9057500433302695	[27,13]	[3,4]	-9	hSpCas9	positive selection	3188108
52770650	52770673		+	24336571	A375	viability after 7 days	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.014868042401770643	[46]	[47,39]	0	hSpCas9	negative selection	3245895
52770669	52770692		-	24336571	A375	viability after 7 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.26284794684848634	[42]	[33,34]	-4	hSpCas9	negative selection	3245896
52766169	52766192		+	24336571	A375	viability after 7 days	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.5177457897872906	[39]	[53,55]	7	hSpCas9	negative selection	3245897
52766255	52766278		+	24336571	A375	viability after 7 days	CACAGTGGTTCTCTAACACTCGG	NEK4	ENSG00000114904	0.39994148518924016	[17]	[23,20]	6	hSpCas9	negative selection	3245899
52766333	52766356		+	24336571	A375	viability after 7 days	GAGTTTTCAGATCTCGATGAAGG	NEK4	ENSG00000114904	-0.46248505135334195	[6]	[4,4]	-6	hSpCas9	negative selection	3245900
52770717	52770740		-	24336571	A375	viability after 7 days	TGGCCGCCTACTGCTACCTGCGG	NEK4	ENSG00000114904	0.43764530494479525	[12]	[18,13]	6	hSpCas9	negative selection	3245901
52770650	52770673		+	24336571	A375	viability after 14 days	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.07252287168007565	[46]	[55,36]	0	hSpCas9	negative selection	3303688
52770669	52770692		-	24336571	A375	viability after 14 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.3442598436360045	[42]	[30,32]	-4	hSpCas9	negative selection	3303689
52766169	52766192		+	24336571	A375	viability after 14 days	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.6835208804745287	[39]	[60,60]	8	hSpCas9	negative selection	3303690
52766255	52766278		+	24336571	A375	viability after 14 days	CACAGTGGTTCTCTAACACTCGG	NEK4	ENSG00000114904	0.582543361622089	[17]	[23,25]	7	hSpCas9	negative selection	3303692
52766333	52766356		+	24336571	A375	viability after 14 days	GAGTTTTCAGATCTCGATGAAGG	NEK4	ENSG00000114904	-0.06318222529309547	[6]	[7,4]	0	hSpCas9	negative selection	3303693
52770717	52770740		-	24336571	A375	viability after 14 days	TGGCCGCCTACTGCTACCTGCGG	NEK4	ENSG00000114904	0.7769921854306923	[12]	[27,13]	8	hSpCas9	negative selection	3303694
52766169	52766192	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	-2.066854335172906	[640,640]	[0,0]	-9	hSpCas9	positive selection	3381450
52765929	52765952	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.2020437759446454	[265,265]	[1,1]	1	hSpCas9	positive selection	3381451
52765955	52765978	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	1.107579091941153	[70,70]	[0,0]	5	hSpCas9	positive selection	3381452
52766267	52766290	3	+	26780180	HT29	viability (Avana library 4 designs)	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	0.438253758150671	[]	[]	1	hSpCas9	negative selection	3443082
52770665	52770688	3	-	26780180	HT29	viability (Avana library 4 designs)	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	1.37910497160648	[]	[]	5	hSpCas9	negative selection	3443083
52763502	52763525	3	-	26780180	HT29	viability (Avana library 4 designs)	TGAGGCAGCCTTATATAAAGCGG	NEK4	ENSG00000114904	1.02448717480358	[]	[]	4	hSpCas9	negative selection	3443084
52752300	52752323	3	-	26780180	HT29	viability (Avana library 4 designs)	TTTGTCCCAGGAGAAACCCAGGG	NEK4	ENSG00000114904	2.25272789734312	[]	[]	7	hSpCas9	negative selection	3443085
52752300	52752323	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGTCCCAGGAGAAACCCAGGG	NEK4	ENSG00000114904	-1.1296937290571	[]	[]	-1	hSpCas9	negative selection	3534597
52763502	52763525	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGGCAGCCTTATATAAAGCGG	NEK4	ENSG00000114904	-0.550330929140739	[]	[]	0	hSpCas9	negative selection	3534598
52766267	52766290	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	2.614925055068	[]	[]	4	hSpCas9	negative selection	3534599
52770665	52770688	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	1.37463335927736	[]	[]	2	hSpCas9	negative selection	3534600
52752174	52752197	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATCTTACCTGCAAAAGGGAGGG	NEK4	ENSG00000114904	-7.45713801739182	[]	[]	-6	hSpCas9	negative selection	3534601
52752104	52752127	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGCCTCTAATGAGTTAGGAGG	NEK4	ENSG00000114904	5.68913692552552	[]	[]	8	hSpCas9	negative selection	3534602
52752300	52752323	3	-	26780180	A375	viability (Avana lentiGuide)	TTTGTCCCAGGAGAAACCCAGGG	NEK4	ENSG00000114904	10.9505369198079	[]	[]	7	hSpCas9	negative selection	3643256
52763502	52763525	3	-	26780180	A375	viability (Avana lentiGuide)	TGAGGCAGCCTTATATAAAGCGG	NEK4	ENSG00000114904	1.05797583997766	[]	[]	1	hSpCas9	negative selection	3643257
52766267	52766290	3	+	26780180	A375	viability (Avana lentiGuide)	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	-2.71611775787034	[]	[]	-5	hSpCas9	negative selection	3643258
52770665	52770688	3	-	26780180	A375	viability (Avana lentiGuide)	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	16.8132434811041	[]	[]	8	hSpCas9	negative selection	3643259
52752174	52752197	3	-	26780180	A375	viability (Avana lentiGuide)	CATCTTACCTGCAAAAGGGAGGG	NEK4	ENSG00000114904	2.7999580183553	[]	[]	3	hSpCas9	negative selection	3643260
52752104	52752127	3	-	26780180	A375	viability (Avana lentiGuide)	GATGCCTCTAATGAGTTAGGAGG	NEK4	ENSG00000114904	0.450347687159236	[]	[]	0	hSpCas9	negative selection	3643261
52752300	52752323	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGTCCCAGGAGAAACCCAGGG	NEK4	ENSG00000114904	-0.2268848616697727	[4]	[3,3]	-4	hSpCas9	positive selection	3751915
52763502	52763525	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGGCAGCCTTATATAAAGCGG	NEK4	ENSG00000114904	0.061470450919359765	[5]	[5,5]	1	hSpCas9	positive selection	3751916
52766267	52766290	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	-0.09314734114701752	[4]	[5,3]	-1	hSpCas9	positive selection	3751917
52770665	52770688	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.3643479198090125	[4]	[5,5]	9	hSpCas9	positive selection	3751918
52752174	52752197	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCTTACCTGCAAAAGGGAGGG	NEK4	ENSG00000114904	-0.34521171378623244	[5]	[4,3]	-5	hSpCas9	positive selection	3751919
52752104	52752127	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGCCTCTAATGAGTTAGGAGG	NEK4	ENSG00000114904	0.27603642023808994	[4]	[6,5]	7	hSpCas9	positive selection	3751920
52752300	52752323	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGTCCCAGGAGAAACCCAGGG	NEK4	ENSG00000114904	-0.36650480831196297	[4]	[1,3]	-5	hSpCas9	positive selection	3860522
52763502	52763525	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGGCAGCCTTATATAAAGCGG	NEK4	ENSG00000114904	-0.2029304433083871	[5]	[4,3]	-3	hSpCas9	positive selection	3860523
52766267	52766290	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAACACTCGGGCAATTCCTAGG	NEK4	ENSG00000114904	0.22777984137169568	[5]	[6,5]	6	hSpCas9	positive selection	3860524
52770665	52770688	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	-0.03349664691684745	[4]	[4,2]	0	hSpCas9	positive selection	3860525
52752174	52752197	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCTTACCTGCAAAAGGGAGGG	NEK4	ENSG00000114904	0.06879017670411994	[5]	[4,4]	1	hSpCas9	positive selection	3860526
52752104	52752127	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGCCTCTAATGAGTTAGGAGG	NEK4	ENSG00000114904	0.29544549413305576	[4]	[6,4]	8	hSpCas9	positive selection	3860527
52770650	52770673	3	+	26780180	A375	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.765453065947384	[]	[]	3	hSpCas9	negative selection	3971850
52765955	52765978	3	-	26780180	A375	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	1.13034562334605	[]	[]	5	hSpCas9	negative selection	3971851
52770669	52770692	3	-	26780180	A375	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	1.35627216818626	[]	[]	7	hSpCas9	negative selection	3971852
52766169	52766192	3	+	26780180	A375	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	-0.206287278138929	[]	[]	-6	hSpCas9	negative selection	3971853
52765929	52765952	3	+	26780180	A375	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.517154793811897	[]	[]	1	hSpCas9	negative selection	3971854
52766219	52766242	3	+	26780180	A375	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	1.1740869755417	[]	[]	6	hSpCas9	negative selection	3971855
52770650	52770673	3	+	26780180	HT29	viability (GeCKOv2 library)	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.791486807543952	[]	[]	3	hSpCas9	negative selection	4079816
52765955	52765978	3	-	26780180	HT29	viability (GeCKOv2 library)	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	1.55031734648529	[]	[]	7	hSpCas9	negative selection	4079817
52770669	52770692	3	-	26780180	HT29	viability (GeCKOv2 library)	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	1.56146319989382	[]	[]	8	hSpCas9	negative selection	4079818
52766169	52766192	3	+	26780180	HT29	viability (GeCKOv2 library)	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.396068659577745	[]	[]	1	hSpCas9	negative selection	4079819
52765929	52765952	3	+	26780180	HT29	viability (GeCKOv2 library)	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.878155651007151	[]	[]	4	hSpCas9	negative selection	4079820
52766219	52766242	3	+	26780180	HT29	viability (GeCKOv2 library)	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	1.24592110160471	[]	[]	6	hSpCas9	negative selection	4079821
52770650	52770673	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.12326508981649753	[5]	[3,4]	3	hSpCas9	positive selection	4154948
52770669	52770692	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.14702724613379614	[5]	[3,4]	4	hSpCas9	positive selection	4154949
52766169	52766192	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.24951521846586783	[5]	[3,4]	6	hSpCas9	positive selection	4154950
52766255	52766278	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACAGTGGTTCTCTAACACTCGG	NEK4	ENSG00000114904	0.0636817187894742	[4]	[2,3]	1	hSpCas9	positive selection	4154952
52766333	52766356	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGTTTTCAGATCTCGATGAAGG	NEK4	ENSG00000114904	0.6902819964997562	[1]	[1,1]	9	hSpCas9	positive selection	4154953
52770717	52770740	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGCCGCCTACTGCTACCTGCGG	NEK4	ENSG00000114904	-0.05314724565012058	[3]	[2,2]	-1	hSpCas9	positive selection	4154954
52770650	52770673	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	1.1400669851373864	[5]	[5,4,4,4]	8	hSpCas9	positive selection	4218970
52770669	52770692	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.28865147377439915	[5]	[0,4,0,3]	2	hSpCas9	positive selection	4218971
52766169	52766192	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.9472472756766692	[5]	[5,4,4,3]	6	hSpCas9	positive selection	4218972
52766255	52766278	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACAGTGGTTCTCTAACACTCGG	NEK4	ENSG00000114904	1.1220309317669315	[4]	[2,3,4,4]	8	hSpCas9	positive selection	4218974
52766333	52766356	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGTTTTCAGATCTCGATGAAGG	NEK4	ENSG00000114904	0.8734121123051745	[3]	[3,0,0,3]	6	hSpCas9	positive selection	4218975
52770717	52770740	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGCCGCCTACTGCTACCTGCGG	NEK4	ENSG00000114904	1.2827187144743608	[3]	[0,4,5,4]	9	hSpCas9	positive selection	4218976
52770650	52770673	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.36857329382648324	[2]	[1,0]	-7	hSpCas9	positive selection	4285308
52770669	52770692	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.005610644491460981	[3]	[2,2]	0	hSpCas9	positive selection	4285309
52766219	52766242	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	-0.14946751976780864	[2]	[2,0]	-3	hSpCas9	positive selection	4285310
52766169	52766192	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.1648867299418041	[4]	[4,3]	3	hSpCas9	positive selection	4349566
52765929	52765952	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.09314173644535034	[3]	[3,1]	2	hSpCas9	positive selection	4349567
52765955	52765978	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.28942455535828515	[2]	[2,0]	-5	hSpCas9	positive selection	4349568
52763505	52763527	3	+	27760321	OCIAML3	viability	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	0.6857493224778433	[476,420]	[499,646]	7	hSpCas9	negative selection	4421890
52763597	52763619	3	+	27760321	OCIAML3	viability	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	0.7959651849279701	[824,699]	[809,1320]	8	hSpCas9	negative selection	4421891
52765886	52765908	3	-	27760321	OCIAML3	viability	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	-1.906434656347657	[21,16]	[0,7]	-9	hSpCas9	negative selection	4421892
52766173	52766195	3	-	27760321	OCIAML3	viability	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	0.5740067785118388	[18,14]	[0,43]	6	hSpCas9	negative selection	4421893
52752241	52752263	3	+	27760321	OCIAML3	viability	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	0.9188408410646356	[523,396]	[450,967]	9	hSpCas9	negative selection	4421894
52763505	52763527	3	+	27760321	OCIAML2	viability	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	0.21371678999756996	[476,420]	[375,478]	3	hSpCas9	negative selection	4505353
52763597	52763619	3	+	27760321	OCIAML2	viability	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	0.3415724344015285	[824,699]	[727,845]	4	hSpCas9	negative selection	4505354
52765886	52765908	3	-	27760321	OCIAML2	viability	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	0.44756217300309675	[21,16]	[10,34]	6	hSpCas9	negative selection	4505355
52766173	52766195	3	-	27760321	OCIAML2	viability	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	0.7618097871863787	[18,14]	[39,0]	8	hSpCas9	negative selection	4505356
52752241	52752263	3	+	27760321	OCIAML2	viability	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	0.8949600196142451	[523,396]	[599,801]	9	hSpCas9	negative selection	4505357
52763505	52763527	3	+	27760321	MV411	viability	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	1.0383929255905302	[476,420]	[674,505]	7	hSpCas9	negative selection	4588816
52763597	52763619	3	+	27760321	MV411	viability	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	1.0388700608270416	[824,699]	[1114,902]	7	hSpCas9	negative selection	4588817
52765886	52765908	3	-	27760321	MV411	viability	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	3.428664759926848	[21,16]	[87,211]	9	hSpCas9	negative selection	4588818
52766173	52766195	3	-	27760321	MV411	viability	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	3.851167385079827	[18,14]	[0,400]	9	hSpCas9	negative selection	4588819
52752241	52752263	3	+	27760321	MV411	viability	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	1.338205886868719	[523,396]	[710,838]	8	hSpCas9	negative selection	4588820
52763505	52763527	3	+	27760321	HL60	viability	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	0.12331428556260507	[476,420]	[324,476]	1	hSpCas9	negative selection	4672279
52763597	52763619	3	+	27760321	HL60	viability	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	0.6554265452601373	[824,699]	[983,970]	7	hSpCas9	negative selection	4672280
52765886	52765908	3	-	27760321	HL60	viability	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	0.9130759270611741	[21,16]	[38,19]	8	hSpCas9	negative selection	4672281
52766173	52766195	3	-	27760321	HL60	viability	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	-2.7654562013139765	[18,14]	[2,0]	-9	hSpCas9	negative selection	4672282
52752241	52752263	3	+	27760321	HL60	viability	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	1.3589987643364585	[523,396]	[1011,898]	9	hSpCas9	negative selection	4672283
52763505	52763527	3	+	27760321	HT1080	viability	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	1.3310623593267956	[420,328]	[172,597]	7	hSpCas9	negative selection	4755742
52763597	52763619	3	+	27760321	HT1080	viability	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	-2.131085538461943	[699,545]	[80,29]	-6	hSpCas9	negative selection	4755743
52765886	52765908	3	-	27760321	HT1080	viability	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	-2.57725339867981	[16,12]	[0,0]	-7	hSpCas9	negative selection	4755744
52766173	52766195	3	-	27760321	HT1080	viability	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	6.2985340097772164	[14,11]	[338,516]	9	hSpCas9	negative selection	4755745
52752241	52752263	3	+	27760321	HT1080	viability	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	0.5959710174946707	[396,309]	[93,342]	3	hSpCas9	negative selection	4755746
52763505	52763527	3	+	27760321	HT29	viability after 7 days	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	-0.18104267860503176	[420,328]	[437,186,644]	-3	hSpCas9	negative selection	4839205
52763597	52763619	3	+	27760321	HT29	viability after 7 days	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	0.5249857522179673	[699,545]	[1121,872,1446]	7	hSpCas9	negative selection	4839206
52765886	52765908	3	-	27760321	HT29	viability after 7 days	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	0.5155964184081947	[16,12]	[81,1,6]	7	hSpCas9	negative selection	4839207
52766173	52766195	3	-	27760321	HT29	viability after 7 days	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	-0.4612508583249282	[14,11]	[38,1,0]	-6	hSpCas9	negative selection	4839208
52752241	52752263	3	+	27760321	HT29	viability after 7 days	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	0.6220363551233223	[396,309]	[763,619,721]	8	hSpCas9	negative selection	4839209
52763505	52763527	3	+	27760321	HT29	viability after 25 days	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	-0.16986660681658633	[420,328]	[260,472,419]	-2	hSpCas9	negative selection	4922668
52763597	52763619	3	+	27760321	HT29	viability after 25 days	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	0.9187210113116937	[699,545]	[1230,1335,1490]	9	hSpCas9	negative selection	4922669
52765886	52765908	3	-	27760321	HT29	viability after 25 days	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	0.9348807859620214	[16,12]	[0,58,40]	9	hSpCas9	negative selection	4922670
52766173	52766195	3	-	27760321	HT29	viability after 25 days	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	-0.49864327582923185	[14,11]	[15,0,15]	-4	hSpCas9	negative selection	4922671
52752241	52752263	3	+	27760321	HT29	viability after 25 days	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	1.2544923351764534	[396,309]	[975,909,1007]	9	hSpCas9	negative selection	4922672
52763505	52763527	3	+	27760321	HT29	viability after 22 days	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	-0.08212674310214899	[420,328]	[235,520,476]	-1	hSpCas9	negative selection	5006131
52763597	52763619	3	+	27760321	HT29	viability after 22 days	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	0.9835609459538457	[699,545]	[1284,1346,1645]	9	hSpCas9	negative selection	5006132
52765886	52765908	3	-	27760321	HT29	viability after 22 days	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	1.4137845500094905	[16,12]	[18,90,28]	9	hSpCas9	negative selection	5006133
52766173	52766195	3	-	27760321	HT29	viability after 22 days	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	0.08146110154246067	[14,11]	[36,1,9]	0	hSpCas9	negative selection	5006134
52752241	52752263	3	+	27760321	HT29	viability after 22 days	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	1.1855992088661582	[396,309]	[906,980,900]	9	hSpCas9	negative selection	5006135
52763505	52763527	3	+	27760321	HT29	viability after 19 days	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	0.050384128673890104	[420,328]	[504,508,328]	0	hSpCas9	negative selection	5089594
52763597	52763619	3	+	27760321	HT29	viability after 19 days	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	0.9573028012210363	[699,545]	[1233,1310,1580]	8	hSpCas9	negative selection	5089595
52765886	52765908	3	-	27760321	HT29	viability after 19 days	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	0.4141548861182889	[16,12]	[46,0,22]	4	hSpCas9	negative selection	5089596
52766173	52766195	3	-	27760321	HT29	viability after 19 days	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	1.150737060349364	[14,11]	[57,0,45]	9	hSpCas9	negative selection	5089597
52752241	52752263	3	+	27760321	HT29	viability after 19 days	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	1.3341334653469765	[396,309]	[966,854,1221]	9	hSpCas9	negative selection	5089598
52763505	52763527	3	+	27760321	HT29	viability after 16 days	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	-0.5178639172047206	[420,328]	[344,368,167]	-5	hSpCas9	negative selection	5173057
52763597	52763619	3	+	27760321	HT29	viability after 16 days	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	0.6445167549556599	[699,545]	[1312,1187,785]	7	hSpCas9	negative selection	5173058
52765886	52765908	3	-	27760321	HT29	viability after 16 days	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	1.7774134391164056	[16,12]	[45,29,95]	9	hSpCas9	negative selection	5173059
52766173	52766195	3	-	27760321	HT29	viability after 16 days	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	-2.51784724052297	[14,11]	[2,0,3]	-8	hSpCas9	negative selection	5173060
52752241	52752263	3	+	27760321	HT29	viability after 16 days	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	0.8631903857005329	[396,309]	[892,475,811]	8	hSpCas9	negative selection	5173061
52763505	52763527	3	+	27760321	HT29	viability after 13 days	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	0.1152093843914585	[420,328]	[667,304,441]	1	hSpCas9	negative selection	5256520
52763597	52763619	3	+	27760321	HT29	viability after 13 days	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	0.3970036433957942	[699,545]	[690,1222,941]	5	hSpCas9	negative selection	5256521
52765886	52765908	3	-	27760321	HT29	viability after 13 days	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	0.7381136022616532	[16,12]	[38,19,27]	8	hSpCas9	negative selection	5256522
52766173	52766195	3	-	27760321	HT29	viability after 13 days	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	-0.2802305640968523	[14,11]	[9,2,24]	-3	hSpCas9	negative selection	5256523
52752241	52752263	3	+	27760321	HT29	viability after 13 days	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	1.1985265769196303	[396,309]	[1092,956,782]	9	hSpCas9	negative selection	5256524
52763505	52763527	3	+	27760321	HT29	viability after 10 days	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	-0.03994200434172168	[420,328]	[310,513,540]	0	hSpCas9	negative selection	5339983
52763597	52763619	3	+	27760321	HT29	viability after 10 days	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	0.6766250127965479	[699,545]	[1232,1255,1240]	8	hSpCas9	negative selection	5339984
52765886	52765908	3	-	27760321	HT29	viability after 10 days	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	-0.0255617719303336	[16,12]	[26,11,15]	0	hSpCas9	negative selection	5339985
52766173	52766195	3	-	27760321	HT29	viability after 10 days	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	-0.5858518019128258	[14,11]	[0,0,30]	-6	hSpCas9	negative selection	5339986
52752241	52752263	3	+	27760321	HT29	viability after 10 days	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	1.123949558030473	[396,309]	[705,821,1344]	9	hSpCas9	negative selection	5339987
52763505	52763527	3	+	27760321	MOLM13	viability	CTTTATATAAGGCTGCCTCAGG	NEK4	ENSG00000114904	0.49996944791779335	[476,420]	[194,495]	3	hSpCas9	negative selection	5423446
52763597	52763619	3	+	27760321	MOLM13	viability	GGCTGTAATCTCTTGGCATTGG	NEK4	ENSG00000114904	0.6639163954607088	[824,699]	[648,704]	4	hSpCas9	negative selection	5423447
52765886	52765908	3	-	27760321	MOLM13	viability	TATCGGATTATTGAAGGAAAGG	NEK4	ENSG00000114904	0.8659202721118806	[21,16]	[0,35]	6	hSpCas9	negative selection	5423448
52766173	52766195	3	-	27760321	MOLM13	viability	AACCCTACAACTATAAGGTAGG	NEK4	ENSG00000114904	-3.2525033557859855	[18,14]	[0,0]	-9	hSpCas9	negative selection	5423449
52752241	52752263	3	+	27760321	MOLM13	viability	CAAGTCCTGTTTGCAGGTATGG	NEK4	ENSG00000114904	1.5297213607236007	[523,396]	[923,590]	9	hSpCas9	negative selection	5423450
52770714	52770737	3	+	27661255	K562	viability	GACCCGCAGGTAGCAGTAGGCGG	NEK4	ENSG00000114904	-0.21322760610171498	[629,590]	[452,393]	-6	dCas9-KRAB	negative selection	5496201
52770694	52770717	3	-	27661255	K562	viability	GTCGTGGGCAAGGGGAGCTATGG	NEK4	ENSG00000114904	0.03739013711407879	[891,878]	[886,588]	1	dCas9-KRAB	negative selection	5496202
52770906	52770929	3	-	27661255	K562	viability	GGCCCGGATCGCTATGGCAGCGG	NEK4	ENSG00000114904	0.08211465121890171	[1030,1154]	[944,902]	3	dCas9-KRAB	negative selection	5496203
52770912	52770935	3	-	27661255	K562	viability	GCTCCCGGCCCGGATCGCTATGG	NEK4	ENSG00000114904	0.17383043702686304	[784,752]	[754,640]	6	dCas9-KRAB	negative selection	5496204
52770650	52770673	3	+	27260156	BXPC3	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	9.853359964107078e-05	[237]	[192,264,264,279]	0	hSpCas9	negative selection	5557768
52770669	52770692	3	-	27260156	BXPC3	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.1071429227664113	[649]	[753,647,804,717]	2	hSpCas9	negative selection	5557769
52766219	52766242	3	+	27260156	BXPC3	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.1950908744263372	[269]	[289,337,395,262]	4	hSpCas9	negative selection	5557770
52766169	52766192	3	+	27260156	BXPC3	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.14230823360281786	[1426]	[1414,1586,1661,1981]	3	hSpCas9	negative selection	5622026
52765929	52765952	3	+	27260156	BXPC3	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.22744628142980072	[616]	[715,706,858,740]	5	hSpCas9	negative selection	5622027
52765955	52765978	3	-	27260156	BXPC3	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.5866329952646862	[328]	[165,269,258,223]	-8	hSpCas9	negative selection	5622028
52770650	52770673	3	+	27260156	A673	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.031599308716336205	[237]	[234,251,283,345]	-1	hSpCas9	negative selection	5679019
52770669	52770692	3	-	27260156	A673	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.22412280192527761	[649]	[1014,694,1056,892]	5	hSpCas9	negative selection	5679020
52766219	52766242	3	+	27260156	A673	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.14080798885070045	[269]	[346,378,363,335]	3	hSpCas9	negative selection	5679021
52766169	52766192	3	+	27260156	A673	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.1071612838239333	[1426]	[2062,1500,1756,2106]	2	hSpCas9	negative selection	5743277
52765929	52765952	3	+	27260156	A673	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.13993905297607456	[616]	[978,878,602,821]	3	hSpCas9	negative selection	5743278
52765955	52765978	3	-	27260156	A673	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.3060389415070677	[328]	[445,292,169,388]	-6	hSpCas9	negative selection	5743279
52770650	52770673	3	+	27260156	A375	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.1225958552326587	[237]	[330,301,153,241]	-2	hSpCas9	negative selection	5800270
52770669	52770692	3	-	27260156	A375	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.292459181164491	[649]	[607,823,578,507]	-4	hSpCas9	negative selection	5800271
52766219	52766242	3	+	27260156	A375	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.3480202020421254	[269]	[500,436,337,340]	5	hSpCas9	negative selection	5800272
52766169	52766192	3	+	27260156	A375	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.25290049091908084	[1426]	[1956,2311,1757,1957]	3	hSpCas9	negative selection	5864528
52765929	52765952	3	+	27260156	A375	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.2802584530170553	[616]	[997,1069,773,703]	4	hSpCas9	negative selection	5864529
52765955	52765978	3	-	27260156	A375	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.12490683818957549	[328]	[412,553,267,217]	-2	hSpCas9	negative selection	5864530
52770650	52770673	3	+	27260156	COLO741	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.319109949958869	[237]	[240,252,236]	-6	hSpCas9	negative selection	5921521
52770669	52770692	3	-	27260156	COLO741	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.19319609670208215	[649]	[760,755,667]	-4	hSpCas9	negative selection	5921522
52766219	52766242	3	+	27260156	COLO741	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.1415628042480429	[269]	[482,295,370]	3	hSpCas9	negative selection	5921523
52766169	52766192	3	+	27260156	COLO741	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.18528866571953917	[1426]	[2469,1820,1964]	4	hSpCas9	negative selection	5985779
52765929	52765952	3	+	27260156	COLO741	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	-0.05684217816817688	[616]	[942,707,644]	-1	hSpCas9	negative selection	5985780
52765955	52765978	3	-	27260156	COLO741	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.6328836941709849	[328]	[253,240,312]	-8	hSpCas9	negative selection	5985781
52770650	52770673	3	+	27260156	CAL120	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.20958053500452523	[237]	[589,56,172]	-3	hSpCas9	negative selection	6042772
52770669	52770692	3	-	27260156	CAL120	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.5010328616240279	[649]	[873,488,399]	-6	hSpCas9	negative selection	6042773
52766219	52766242	3	+	27260156	CAL120	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.09948605875392225	[269]	[187,567,298]	1	hSpCas9	negative selection	6042774
52766169	52766192	3	+	27260156	CAL120	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	-0.07766067031869683	[1426]	[1999,1351,1741]	-1	hSpCas9	negative selection	6107030
52765929	52765952	3	+	27260156	CAL120	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.11376136829745742	[616]	[1122,751,663]	1	hSpCas9	negative selection	6107031
52765955	52765978	3	-	27260156	CAL120	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-1.0035584133670032	[328]	[216,168,227]	-8	hSpCas9	negative selection	6107032
52770650	52770673	3	+	27260156	CADOES1	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.2842808479149934	[237]	[239,145,205,132]	-5	hSpCas9	negative selection	6164023
52770669	52770692	3	-	27260156	CADOES1	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.2926837580101014	[649]	[422,452,507,593]	-5	hSpCas9	negative selection	6164024
52766219	52766242	3	+	27260156	CADOES1	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.26260097032135166	[269]	[285,292,324,300]	4	hSpCas9	negative selection	6164025
52766169	52766192	3	+	27260156	CADOES1	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.4044248328254316	[1426]	[1654,1646,1724,2008]	6	hSpCas9	negative selection	6228281
52765929	52765952	3	+	27260156	CADOES1	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.5014995024689571	[616]	[629,892,892,834]	8	hSpCas9	negative selection	6228282
52765955	52765978	3	-	27260156	CADOES1	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.07721846622753337	[328]	[285,343,196,334]	-1	hSpCas9	negative selection	6228283
52770650	52770673	3	+	27260156	EWS502	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.2093448310717756	[237]	[82,339,322,131]	-4	hSpCas9	negative selection	6285274
52770669	52770692	3	-	27260156	EWS502	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.00851748596987012	[649]	[795,510,725,696]	0	hSpCas9	negative selection	6285275
52766219	52766242	3	+	27260156	EWS502	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	-0.23085300694291555	[269]	[166,303,281,226]	-4	hSpCas9	negative selection	6285276
52766169	52766192	3	+	27260156	EWS502	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.2142136346442236	[1426]	[1679,1662,1743,1945]	4	hSpCas9	negative selection	6349532
52765929	52765952	3	+	27260156	EWS502	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.3069016041441278	[616]	[613,876,911,852]	5	hSpCas9	negative selection	6349533
52765955	52765978	3	-	27260156	EWS502	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	0.04682535955250827	[328]	[258,371,293,536]	0	hSpCas9	negative selection	6349534
52770650	52770673	3	+	27260156	EW8	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.3147887709102104	[237]	[228,174,108,122]	-5	hSpCas9	negative selection	6406525
52770669	52770692	3	-	27260156	EW8	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.022175541497144124	[649]	[645,572,507,362]	0	hSpCas9	negative selection	6406526
52766219	52766242	3	+	27260156	EW8	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	-0.06943860784513922	[269]	[277,172,136,264]	-1	hSpCas9	negative selection	6406527
52766169	52766192	3	+	27260156	EW8	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.20946663561799816	[1426]	[1648,1356,1157,1245]	4	hSpCas9	negative selection	6470783
52765929	52765952	3	+	27260156	EW8	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.20529888597079338	[616]	[688,588,588,447]	4	hSpCas9	negative selection	6470784
52765955	52765978	3	-	27260156	EW8	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.2574251911636183	[328]	[141,232,255,245]	-5	hSpCas9	negative selection	6470785
52770650	52770673	3	+	27260156	CORL105	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.3500957014565488	[237]	[366,344,260,432]	6	hSpCas9	negative selection	6527776
52770669	52770692	3	-	27260156	CORL105	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.3088719760230955	[649]	[1000,893,866,998]	6	hSpCas9	negative selection	6527777
52766219	52766242	3	+	27260156	CORL105	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.45799443724703576	[269]	[377,365,624,396]	8	hSpCas9	negative selection	6527778
52766169	52766192	3	+	27260156	CORL105	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.19667750303594866	[1426]	[1958,1751,2315,1698]	3	hSpCas9	negative selection	6592034
52765929	52765952	3	+	27260156	CORL105	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.10167557780514752	[616]	[774,707,943,700]	2	hSpCas9	negative selection	6592035
52765955	52765978	3	-	27260156	CORL105	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.4021663783102991	[328]	[249,327,412,191]	-6	hSpCas9	negative selection	6592036
52770650	52770673	3	+	27260156	HS294T	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.34803191060051986	[237]	[185,74,78,123]	5	hSpCas9	negative selection	6649027
52770669	52770692	3	-	27260156	HS294T	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.46610263278595804	[649]	[407,454,271,221]	6	hSpCas9	negative selection	6649028
52766219	52766242	3	+	27260156	HS294T	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.7474432579335885	[269]	[153,198,206,134]	8	hSpCas9	negative selection	6649029
52766169	52766192	3	+	27260156	HS294T	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.08012375538528493	[1426]	[494,572,603,684]	1	hSpCas9	negative selection	6713285
52765929	52765952	3	+	27260156	HS294T	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.18122807573851107	[616]	[224,306,287,262]	2	hSpCas9	negative selection	6713286
52765955	52765978	3	-	27260156	HS294T	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.053426865807586044	[328]	[49,56,240,156]	0	hSpCas9	negative selection	6713287
52770650	52770673	3	+	27260156	HCC44	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.24970710768547433	[237]	[315,445,300,196]	4	hSpCas9	negative selection	6770278
52770669	52770692	3	-	27260156	HCC44	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.25334077564590274	[649]	[751,445,789,542]	-4	hSpCas9	negative selection	6770279
52766219	52766242	3	+	27260156	HCC44	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	-0.0014582658440556173	[269]	[358,292,266,298]	0	hSpCas9	negative selection	6770280
52766169	52766192	3	+	27260156	HCC44	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.18754144304137066	[1426]	[1770,1736,2089,1791]	3	hSpCas9	negative selection	6834536
52765929	52765952	3	+	27260156	HCC44	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.12262311533655579	[616]	[889,682,971,553]	2	hSpCas9	negative selection	6834537
52765955	52765978	3	-	27260156	HCC44	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	0.0906036524539865	[328]	[424,329,269,541]	1	hSpCas9	negative selection	6834538
52770650	52770673	3	+	27260156	G402	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.3693485123154212	[237]	[143,194,363,183]	-5	hSpCas9	negative selection	6891529
52770669	52770692	3	-	27260156	G402	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.05721769402657467	[649]	[1055,509,555,942]	0	hSpCas9	negative selection	6891530
52766219	52766242	3	+	27260156	G402	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.12245487639443475	[269]	[290,263,230,618]	1	hSpCas9	negative selection	6891531
52766169	52766192	3	+	27260156	G402	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	-0.043317309599957055	[1426]	[2095,1462,1552,1685]	0	hSpCas9	negative selection	6955787
52765929	52765952	3	+	27260156	G402	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.6609584721553737	[616]	[596,1002,1036,1983]	7	hSpCas9	negative selection	6955788
52765955	52765978	3	-	27260156	G402	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-1.0327945848534719	[328]	[423,187,145,64]	-8	hSpCas9	negative selection	6955789
52770650	52770673	3	+	27260156	L33	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.3314330539017296	[237]	[277,115,213,296]	7	hSpCas9	negative selection	7012780
52770669	52770692	3	-	27260156	L33	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.20388520669651972	[649]	[528,241,378,535]	-5	hSpCas9	negative selection	7012781
52766219	52766242	3	+	27260156	L33	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.6356792605833359	[269]	[442,134,288,444]	9	hSpCas9	negative selection	7012782
52766169	52766192	3	+	27260156	L33	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.05452882592222563	[1426]	[1420,707,854,1419]	1	hSpCas9	negative selection	7077038
52765929	52765952	3	+	27260156	L33	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	-0.2469578240782659	[616]	[475,207,367,511]	-5	hSpCas9	negative selection	7077039
52765955	52765978	3	-	27260156	L33	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	0.05522036199395486	[328]	[285,122,236,404]	1	hSpCas9	negative selection	7077040
52770650	52770673	3	+	27260156	K562	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.12100832117996352	[237]	[167,260,289,198]	1	hSpCas9	negative selection	7134031
52770669	52770692	3	-	27260156	K562	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.29679129201487203	[649]	[425,612,742,987]	4	hSpCas9	negative selection	7134032
52766219	52766242	3	+	27260156	K562	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.38310261419919506	[269]	[366,219,129,507]	5	hSpCas9	negative selection	7134033
52766169	52766192	3	+	27260156	K562	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.42736957803612907	[1426]	[1638,1597,1958,1608]	5	hSpCas9	negative selection	7198289
52765929	52765952	3	+	27260156	K562	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.6342803316524942	[616]	[844,1545,737,360]	7	hSpCas9	negative selection	7198290
52765955	52765978	3	-	27260156	K562	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	0.2030234430798833	[328]	[613,103,379,263]	2	hSpCas9	negative selection	7198291
52770650	52770673	3	+	27260156	HT29	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.0028659303966391825	[237]	[221,306,301,314]	0	hSpCas9	negative selection	7255282
52770669	52770692	3	-	27260156	HT29	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.043635037524393294	[649]	[782,767,679,823]	-1	hSpCas9	negative selection	7255283
52766219	52766242	3	+	27260156	HT29	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.2937920667416507	[269]	[515,413,371,323]	6	hSpCas9	negative selection	7255284
52766169	52766192	3	+	27260156	HT29	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.22047860081774084	[1426]	[2095,2119,2062,1828]	4	hSpCas9	negative selection	7319540
52765929	52765952	3	+	27260156	HT29	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.43698537186423236	[616]	[1163,974,1032,903]	8	hSpCas9	negative selection	7319541
52765955	52765978	3	-	27260156	HT29	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.24761681592564655	[328]	[285,488,285,297]	-5	hSpCas9	negative selection	7319542
52770650	52770673	3	+	27260156	MHHES1	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.30269286905431325	[237]	[449,395,275,235]	5	hSpCas9	negative selection	7376533
52770669	52770692	3	-	27260156	MHHES1	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.17686524048648128	[649]	[1161,598,984,613]	3	hSpCas9	negative selection	7376534
52766219	52766242	3	+	27260156	MHHES1	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.8797275707425171	[269]	[814,504,641,340]	9	hSpCas9	negative selection	7376535
52766169	52766192	3	+	27260156	MHHES1	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.34623415096875365	[1426]	[2078,2455,1969,1737]	6	hSpCas9	negative selection	7440791
52765929	52765952	3	+	27260156	MHHES1	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.30144255083769866	[616]	[1156,892,807,638]	5	hSpCas9	negative selection	7440792
52765955	52765978	3	-	27260156	MHHES1	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.09446085715421859	[328]	[429,451,298,243]	-2	hSpCas9	negative selection	7440793
52770650	52770673	3	+	27260156	MEWO	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.15826660200744302	[237]	[302,237,214]	3	hSpCas9	negative selection	7497784
52770669	52770692	3	-	27260156	MEWO	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.18184644066428174	[649]	[780,675,629]	4	hSpCas9	negative selection	7497785
52766219	52766242	3	+	27260156	MEWO	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	-0.1602502172246537	[269]	[306,178,207]	-4	hSpCas9	negative selection	7497786
52766169	52766192	3	+	27260156	MEWO	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.11734685826767399	[1426]	[1674,1273,1439]	2	hSpCas9	negative selection	7562042
52765929	52765952	3	+	27260156	MEWO	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.3339930027203951	[616]	[769,703,716]	7	hSpCas9	negative selection	7562043
52765955	52765978	3	-	27260156	MEWO	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.7098356121409245	[328]	[266,143,168]	-9	hSpCas9	negative selection	7562044
52770650	52770673	3	+	27260156	LNCAPCLONEFGC	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.030128580856099374	[237]	[240,285,181,160]	0	hSpCas9	negative selection	7619035
52770669	52770692	3	-	27260156	LNCAPCLONEFGC	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.1892516594216298	[649]	[442,471,531,624]	-3	hSpCas9	negative selection	7619036
52766219	52766242	3	+	27260156	LNCAPCLONEFGC	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.19769247701843273	[269]	[199,251,426,267]	3	hSpCas9	negative selection	7619037
52766169	52766192	3	+	27260156	LNCAPCLONEFGC	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.14033280215166055	[1426]	[1293,1385,1653,1402]	2	hSpCas9	negative selection	7683293
52765929	52765952	3	+	27260156	LNCAPCLONEFGC	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.2652638181259528	[616]	[628,619,895,578]	4	hSpCas9	negative selection	7683294
52765955	52765978	3	-	27260156	LNCAPCLONEFGC	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.41908015900973783	[328]	[190,196,237,269]	-6	hSpCas9	negative selection	7683295
52770650	52770673	3	+	27260156	PANC0327	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.4715559882949757	[237]	[108,244,86,721]	7	hSpCas9	negative selection	7740286
52770669	52770692	3	-	27260156	PANC0327	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.2092572654198132	[649]	[568,552,293,579]	-3	hSpCas9	negative selection	7740287
52766219	52766242	3	+	27260156	PANC0327	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.5716396015346461	[269]	[268,387,165,590]	8	hSpCas9	negative selection	7740288
52766169	52766192	3	+	27260156	PANC0327	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.1894761042961628	[1426]	[1817,1461,1310,1218]	3	hSpCas9	negative selection	7804544
52765929	52765952	3	+	27260156	PANC0327	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.0747603135018608	[616]	[524,482,766,541]	1	hSpCas9	negative selection	7804545
52765955	52765978	3	-	27260156	PANC0327	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.3696851201067375	[328]	[258,135,235,287]	-5	hSpCas9	negative selection	7804546
52770650	52770673	3	+	27260156	NCIH2009	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.29463977085902615	[237]	[509,412,319]	4	hSpCas9	negative selection	7861537
52770669	52770692	3	-	27260156	NCIH2009	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.33201339862779844	[649]	[892,779,522]	-4	hSpCas9	negative selection	7861538
52766219	52766242	3	+	27260156	NCIH2009	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.3798712854817421	[269]	[738,369,413]	5	hSpCas9	negative selection	7861539
52766169	52766192	3	+	27260156	NCIH2009	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.22293366228637712	[1426]	[2550,2164,2307]	3	hSpCas9	negative selection	7925795
52765929	52765952	3	+	27260156	NCIH2009	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.24488129493714927	[616]	[1532,796,837]	3	hSpCas9	negative selection	7925796
52765955	52765978	3	-	27260156	NCIH2009	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.6201737673601352	[328]	[308,167,423]	-7	hSpCas9	negative selection	7925797
52770650	52770673	3	+	27260156	NCIH1373	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.033949724267606896	[237]	[136,196,479,67]	0	hSpCas9	negative selection	7982788
52770669	52770692	3	-	27260156	NCIH1373	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.22906883519372956	[649]	[1083,476,607,101]	-2	hSpCas9	negative selection	7982789
52766219	52766242	3	+	27260156	NCIH1373	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	1.09361739835206	[269]	[565,543,614,227]	9	hSpCas9	negative selection	7982790
52766169	52766192	3	+	27260156	NCIH1373	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	-0.046952262898311004	[1426]	[1531,1555,1386,451]	0	hSpCas9	negative selection	8047046
52765929	52765952	3	+	27260156	NCIH1373	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.7923005305918837	[616]	[1169,871,1874,226]	7	hSpCas9	negative selection	8047047
52765955	52765978	3	-	27260156	NCIH1373	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.25499421341642015	[328]	[416,214,187,118]	-3	hSpCas9	negative selection	8047048
52770650	52770673	3	+	27260156	PATU8902	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.37614238112042353	[237]	[613,549,170,449]	4	hSpCas9	negative selection	8104039
52770669	52770692	3	-	27260156	PATU8902	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.0888412063399373	[649]	[1352,752,526,840]	-1	hSpCas9	negative selection	8104040
52766219	52766242	3	+	27260156	PATU8902	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.9227839164144833	[269]	[1086,780,365,694]	8	hSpCas9	negative selection	8104041
52766169	52766192	3	+	27260156	PATU8902	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.40873769208771926	[1426]	[2817,3351,1284,3535]	4	hSpCas9	negative selection	8168297
52765929	52765952	3	+	27260156	PATU8902	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.2283492721766126	[616]	[724,1051,711,1691]	2	hSpCas9	negative selection	8168298
52765955	52765978	3	-	27260156	PATU8902	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.3567534065336022	[328]	[510,223,219,526]	-4	hSpCas9	negative selection	8168299
52770650	52770673	3	+	27260156	PANC1	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.17419620908503863	[237]	[106,287,121,220]	-3	hSpCas9	negative selection	8225290
52770669	52770692	3	-	27260156	PANC1	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.3105972673062647	[649]	[458,504,345,486]	-5	hSpCas9	negative selection	8225291
52766219	52766242	3	+	27260156	PANC1	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.11329700765272266	[269]	[152,345,184,323]	1	hSpCas9	negative selection	8225292
52766169	52766192	3	+	27260156	PANC1	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.21042408834399695	[1426]	[1372,1976,1277,1175]	3	hSpCas9	negative selection	8289548
52765929	52765952	3	+	27260156	PANC1	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.4484727929771942	[616]	[639,757,584,878]	7	hSpCas9	negative selection	8289549
52765955	52765978	3	-	27260156	PANC1	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.7158087865597741	[328]	[169,244,93,187]	-7	hSpCas9	negative selection	8289550
52770650	52770673	3	+	27260156	PANC0813	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.5250331445378326	[237]	[397,288,146,752]	8	hSpCas9	negative selection	8346541
52770669	52770692	3	-	27260156	PANC0813	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.2405189454366486	[649]	[965,1022,761,862]	4	hSpCas9	negative selection	8346542
52766219	52766242	3	+	27260156	PANC0813	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.5716370269979959	[269]	[531,594,405,362]	8	hSpCas9	negative selection	8346543
52766169	52766192	3	+	27260156	PANC0813	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.18712751736995226	[1426]	[1791,2117,1785,1921]	3	hSpCas9	negative selection	8410799
52765929	52765952	3	+	27260156	PANC0813	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.28969861383128004	[616]	[898,1024,704,911]	5	hSpCas9	negative selection	8410800
52765955	52765978	3	-	27260156	PANC0813	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	0.33112556872055776	[328]	[341,541,717,337]	5	hSpCas9	negative selection	8410801
52770650	52770673	3	+	27260156	RDES	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.08691937110519488	[237]	[247,203,318,421]	1	hSpCas9	negative selection	8467792
52770669	52770692	3	-	27260156	RDES	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.0055598915212492495	[649]	[678,737,708,858]	0	hSpCas9	negative selection	8467793
52766219	52766242	3	+	27260156	RDES	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.423605228568367	[269]	[326,423,436,496]	6	hSpCas9	negative selection	8467794
52766169	52766192	3	+	27260156	RDES	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.1861606478572082	[1426]	[1453,1618,1945,2627]	3	hSpCas9	negative selection	8532050
52765929	52765952	3	+	27260156	RDES	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.5709295364381328	[616]	[963,939,1125,1208]	8	hSpCas9	negative selection	8532051
52765955	52765978	3	-	27260156	RDES	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.36818730052746784	[328]	[244,248,344,349]	-6	hSpCas9	negative selection	8532052
52770650	52770673	3	+	27260156	PC3	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.05185192905219127	[237]	[184,195,342,228]	-1	hSpCas9	negative selection	8589043
52770669	52770692	3	-	27260156	PC3	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.04599839896698549	[649]	[339,583,992,818]	-1	hSpCas9	negative selection	8589044
52766219	52766242	3	+	27260156	PC3	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.3475726281592264	[269]	[172,451,445,379]	7	hSpCas9	negative selection	8589045
52766169	52766192	3	+	27260156	PC3	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.12232848148979336	[1426]	[1072,1382,2479,1678]	2	hSpCas9	negative selection	8653301
52765929	52765952	3	+	27260156	PC3	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	-0.09493733322157849	[616]	[368,438,1184,590]	-2	hSpCas9	negative selection	8653302
52765955	52765978	3	-	27260156	PC3	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.0044851596259081195	[328]	[230,315,536,311]	0	hSpCas9	negative selection	8653303
52770650	52770673	3	+	27260156	PATU8988T	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.5936503206407109	[237]	[118,150,107,238]	-7	hSpCas9	negative selection	8710294
52770669	52770692	3	-	27260156	PATU8988T	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.09810737762981153	[649]	[686,637,752,600]	1	hSpCas9	negative selection	8710295
52766219	52766242	3	+	27260156	PATU8988T	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.1649531060981555	[269]	[222,409,152,405]	3	hSpCas9	negative selection	8710296
52766169	52766192	3	+	27260156	PATU8988T	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.23099930767157062	[1426]	[1711,1818,1313,1653]	4	hSpCas9	negative selection	8774552
52765929	52765952	3	+	27260156	PATU8988T	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.3205925015375587	[616]	[914,727,568,768]	5	hSpCas9	negative selection	8774553
52765955	52765978	3	-	27260156	PATU8988T	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.6722044294929649	[328]	[223,225,191,154]	-8	hSpCas9	negative selection	8774554
52770650	52770673	3	+	27260156	T47D	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.13946667945591018	[237]	[337,283,309,290]	3	hSpCas9	negative selection	8831545
52770669	52770692	3	-	27260156	T47D	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.009794226426690977	[649]	[804,728,701,775]	0	hSpCas9	negative selection	8831546
52766219	52766242	3	+	27260156	T47D	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.03909318194743572	[269]	[252,240,378,428]	0	hSpCas9	negative selection	8831547
52766169	52766192	3	+	27260156	T47D	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.11339632192975868	[1426]	[1748,1757,1721,1973]	2	hSpCas9	negative selection	8895803
52765929	52765952	3	+	27260156	T47D	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.1463336238029339	[616]	[835,796,764,783]	3	hSpCas9	negative selection	8895804
52765955	52765978	3	-	27260156	T47D	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.29479930779146035	[328]	[379,245,269,361]	-6	hSpCas9	negative selection	8895805
52770650	52770673	3	+	27260156	SU8686	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.21401136860831071	[237]	[201,290,229,393]	3	hSpCas9	negative selection	8952796
52770669	52770692	3	-	27260156	SU8686	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.4196135665964193	[649]	[834,761,855,1031]	7	hSpCas9	negative selection	8952797
52766219	52766242	3	+	27260156	SU8686	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.624185931142629	[269]	[400,302,473,500]	9	hSpCas9	negative selection	8952798
52766169	52766192	3	+	27260156	SU8686	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.09945287134860781	[1426]	[1298,1311,1573,1997]	1	hSpCas9	negative selection	9017054
52765929	52765952	3	+	27260156	SU8686	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.10903670196034287	[616]	[619,496,672,910]	1	hSpCas9	negative selection	9017055
52765955	52765978	3	-	27260156	SU8686	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.4513090914127519	[328]	[171,196,248,368]	-6	hSpCas9	negative selection	9017056
52770650	52770673	3	+	27260156	SKES1	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.03624142402503994	[237]	[296,261,285,146]	0	hSpCas9	negative selection	9074047
52770669	52770692	3	-	27260156	SKES1	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.1570475184420272	[649]	[618,635,560,522]	-3	hSpCas9	negative selection	9074048
52766219	52766242	3	+	27260156	SKES1	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.3166381714780191	[269]	[268,372,384,308]	6	hSpCas9	negative selection	9074049
52766169	52766192	3	+	27260156	SKES1	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.20146427003377032	[1426]	[1797,1647,1756,1379]	4	hSpCas9	negative selection	9138305
52765929	52765952	3	+	27260156	SKES1	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.13704862376460358	[616]	[710,638,649,697]	3	hSpCas9	negative selection	9138306
52765955	52765978	3	-	27260156	SKES1	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.18252420309290351	[328]	[407,242,334,189]	-4	hSpCas9	negative selection	9138307
52770650	52770673	3	+	27260156	TOV112D	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.07170016740627871	[237]	[285,270,213,238]	1	hSpCas9	negative selection	9195298
52770669	52770692	3	-	27260156	TOV112D	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.2276791272090307	[649]	[637,570,484,539]	-4	hSpCas9	negative selection	9195299
52766219	52766242	3	+	27260156	TOV112D	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.12891672594670478	[269]	[266,200,335,350]	2	hSpCas9	negative selection	9195300
52766169	52766192	3	+	27260156	TOV112D	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.35700858342820707	[1426]	[2598,2206,1227,1452]	6	hSpCas9	negative selection	9259556
52765929	52765952	3	+	27260156	TOV112D	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.46056026835675656	[616]	[934,967,751,782]	8	hSpCas9	negative selection	9259557
52765955	52765978	3	-	27260156	TOV112D	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.3578046217417836	[328]	[189,309,333,202]	-6	hSpCas9	negative selection	9259558
52770650	52770673	3	+	27260156	TC71	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	-0.07985166632017626	[237]	[203,272,278,206]	-2	hSpCas9	negative selection	9316549
52770669	52770692	3	-	27260156	TC71	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.04275230969242466	[649]	[783,665,779,631]	1	hSpCas9	negative selection	9316550
52766219	52766242	3	+	27260156	TC71	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.07069865798888353	[269]	[338,205,304,368]	1	hSpCas9	negative selection	9316551
52766169	52766192	3	+	27260156	TC71	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.0685379685313261	[1426]	[1437,1668,1561,1761]	1	hSpCas9	negative selection	9380807
52765929	52765952	3	+	27260156	TC71	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	-0.044261727520304994	[616]	[600,599,679,686]	-1	hSpCas9	negative selection	9380808
52765955	52765978	3	-	27260156	TC71	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.1272061517102283	[328]	[316,314,358,297]	-3	hSpCas9	negative selection	9380809
52770650	52770673	3	+	27260156	TC32	viability	AGACCTGCTTGCCGTCCCGCCGG	NEK4	ENSG00000114904	0.06023046207410632	[237]	[214,250,238,206]	1	hSpCas9	negative selection	9437800
52770669	52770692	3	-	27260156	TC32	viability	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.21435364134673446	[649]	[643,593,830,799]	4	hSpCas9	negative selection	9437801
52766219	52766242	3	+	27260156	TC32	viability	TGTAGTAGGGTGTGCCAATGAGG	NEK4	ENSG00000114904	0.02136173898603777	[269]	[252,217,273,288]	0	hSpCas9	negative selection	9437802
52766169	52766192	3	+	27260156	TC32	viability	CAATCCTACCTTATAGTTGTAGG	NEK4	ENSG00000114904	0.17371836872847402	[1426]	[1455,1117,1983,1647]	3	hSpCas9	negative selection	9502058
52765929	52765952	3	+	27260156	TC32	viability	TGCATTGAAAGCATGCTTCAAGG	NEK4	ENSG00000114904	0.2974095890492241	[616]	[750,418,834,944]	5	hSpCas9	negative selection	9502059
52765955	52765978	3	-	27260156	TC32	viability	AGGATGCTGTGTCTATGAAATGG	NEK4	ENSG00000114904	-0.5013443767823366	[328]	[221,196,299,158]	-7	hSpCas9	negative selection	9502060
52743424	52743447	3	-	27869803	HPAFII	viability after 27 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.28237486372252185	[97]	[31,50,NaN]	-2	hSpCas9	negative selection	9585747
52746796	52746819	3	+	27869803	HPAFII	viability after 27 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	1.3158785518044196	[374]	[276,668,NaN]	9	hSpCas9	negative selection	9585748
52751913	52751936	3	+	27869803	HPAFII	viability after 27 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-1.2454121540928564	[106]	[2,40,NaN]	-7	hSpCas9	negative selection	9585749
52766240	52766263	3	+	27869803	HPAFII	viability after 27 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.13830781213931775	[736]	[426,425,NaN]	1	hSpCas9	negative selection	9585750
52768541	52768564	3	-	27869803	HPAFII	viability after 27 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	-0.30244420044759973	[424]	[214,152,NaN]	-2	hSpCas9	negative selection	9585751
52770669	52770692	3	-	27869803	HPAFII	viability after 27 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.11539561471390503	[203]	[11,202,NaN]	0	hSpCas9	negative selection	9585752
52743424	52743447	3	-	27869803	HPAFII	viability after 15 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	0.3335094550727269	[97]	[120,139,NaN]	4	hSpCas9	negative selection	9668196
52746796	52746819	3	+	27869803	HPAFII	viability after 15 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.45281949725838533	[374]	[624,505,NaN]	5	hSpCas9	negative selection	9668197
52751913	52751936	3	+	27869803	HPAFII	viability after 15 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-0.22852231060363493	[106]	[99,96,NaN]	-3	hSpCas9	negative selection	9668198
52766240	52766263	3	+	27869803	HPAFII	viability after 15 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.11812308312433228	[736]	[981,572,NaN]	-1	hSpCas9	negative selection	9668199
52768541	52768564	3	-	27869803	HPAFII	viability after 15 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	-0.00454576925000727	[424]	[524,411,NaN]	0	hSpCas9	negative selection	9668200
52770669	52770692	3	-	27869803	HPAFII	viability after 15 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.3490914287589576	[203]	[261,289,NaN]	4	hSpCas9	negative selection	9668201
52743424	52743447	3	-	27869803	ASPC1	viability after 36 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.3251130278743543	[625]	[111,53,311]	-3	hSpCas9	negative selection	9750645
52746796	52746819	3	+	27869803	ASPC1	viability after 36 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.1916706074508342	[818]	[672,226,158]	2	hSpCas9	negative selection	9750646
52751913	52751936	3	+	27869803	ASPC1	viability after 36 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	0.454686552030815	[291]	[173,23,205]	4	hSpCas9	negative selection	9750647
52766240	52766263	3	+	27869803	ASPC1	viability after 36 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.15918969097779412	[1685]	[881,373,393]	-2	hSpCas9	negative selection	9750648
52768541	52768564	3	-	27869803	ASPC1	viability after 36 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.09033282395472253	[994]	[294,441,360]	0	hSpCas9	negative selection	9750649
52770669	52770692	3	-	27869803	ASPC1	viability after 36 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.5329370531724179	[524]	[253,40,103]	-5	hSpCas9	negative selection	9750650
52743424	52743447	3	-	27869803	PATU8988S	viability after 35 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.24674974034368125	[416]	[160,121,NaN]	-3	hSpCas9	negative selection	9833094
52746796	52746819	3	+	27869803	PATU8988S	viability after 35 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.3744531564389414	[725]	[399,357,NaN]	4	hSpCas9	negative selection	9833095
52751913	52751936	3	+	27869803	PATU8988S	viability after 35 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-0.01987004132174164	[179]	[72,69,NaN]	0	hSpCas9	negative selection	9833096
52766240	52766263	3	+	27869803	PATU8988S	viability after 35 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.3051651568357725	[1606]	[447,599,NaN]	-3	hSpCas9	negative selection	9833097
52768541	52768564	3	-	27869803	PATU8988S	viability after 35 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.42287538804076763	[913]	[489,496,NaN]	5	hSpCas9	negative selection	9833098
52770669	52770692	3	-	27869803	PATU8988S	viability after 35 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.0934071477211194	[612]	[190,271,NaN]	-1	hSpCas9	negative selection	9833099
52743424	52743447	3	-	27869803	PATU8988S	viability after 31 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.46136059602684143	[416]	[151,80,NaN]	-5	hSpCas9	negative selection	9915543
52746796	52746819	3	+	27869803	PATU8988S	viability after 31 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	0.2477645644781259	[725]	[381,294,NaN]	3	hSpCas9	negative selection	9915544
52751913	52751936	3	+	27869803	PATU8988S	viability after 31 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	0.1730094015964616	[179]	[72,90,NaN]	2	hSpCas9	negative selection	9915545
52766240	52766263	3	+	27869803	PATU8988S	viability after 31 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.023809297659327378	[1606]	[496,799,NaN]	0	hSpCas9	negative selection	9915546
52768541	52768564	3	-	27869803	PATU8988S	viability after 31 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.5810633886206895	[913]	[359,780,NaN]	7	hSpCas9	negative selection	9915547
52770669	52770692	3	-	27869803	PATU8988S	viability after 31 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.06888195952020792	[612]	[174,359,NaN]	0	hSpCas9	negative selection	9915548
52743424	52743447	3	-	27869803	HPAFII	viability after 35 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-1.992647921022333	[97]	[3,21,NaN]	-7	hSpCas9	negative selection	9997992
52746796	52746819	3	+	27869803	HPAFII	viability after 35 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	1.4203856129474994	[374]	[287,755,NaN]	8	hSpCas9	negative selection	9997993
52751913	52751936	3	+	27869803	HPAFII	viability after 35 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-2.454082665917812	[106]	[15,2,NaN]	-8	hSpCas9	negative selection	9997994
52766240	52766263	3	+	27869803	HPAFII	viability after 35 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.36846296682741175	[736]	[523,433,NaN]	2	hSpCas9	negative selection	9997995
52768541	52768564	3	-	27869803	HPAFII	viability after 35 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	0.013502785431443454	[424]	[219,213,NaN]	0	hSpCas9	negative selection	9997996
52770669	52770692	3	-	27869803	HPAFII	viability after 35 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	0.19814176951981777	[203]	[14,234,NaN]	1	hSpCas9	negative selection	9997997
52743424	52743447	3	-	27869803	HPAFII	viability after 31 days	AAGCGTCTCTGAGTGTAGCAGGG	NEK4	ENSG00000114904	-0.9401562206049214	[97]	[9,48,NaN]	-5	hSpCas9	negative selection	10080441
52746796	52746819	3	+	27869803	HPAFII	viability after 31 days	TTTGCCGTCGCTGTCGAGACAGG	NEK4	ENSG00000114904	1.112664190372842	[374]	[300,622,NaN]	7	hSpCas9	negative selection	10080442
52751913	52751936	3	+	27869803	HPAFII	viability after 31 days	ATGTGTGCATATCACTCACCTGG	NEK4	ENSG00000114904	-2.069432097858148	[106]	[9,18,NaN]	-8	hSpCas9	negative selection	10080443
52766240	52766263	3	+	27869803	HPAFII	viability after 31 days	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.282142053106073	[736]	[501,503,NaN]	2	hSpCas9	negative selection	10080444
52768541	52768564	3	-	27869803	HPAFII	viability after 31 days	AGAGCGGCGAGCTGCTGAACAGG	NEK4	ENSG00000114904	-0.0020480196592641553	[424]	[297,172,NaN]	0	hSpCas9	negative selection	10080445
52770669	52770692	3	-	27869803	HPAFII	viability after 31 days	AGGTGACGCTTGTGAAGCACCGG	NEK4	ENSG00000114904	-0.1824760534816039	[203]	[8,200,NaN]	-1	hSpCas9	negative selection	10080446
52770665	52770688	3	-	28162770	P31FUJ	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.43512174532217607	[106]	[169]	5	hSpCas9	negative selection	10199306
52744257	52744280	3	-	28162770	P31FUJ	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	-0.023625402582094668	[140]	[162]	0	hSpCas9	negative selection	10199307
52766240	52766263	3	+	28162770	P31FUJ	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.2875302377040646	[174]	[250]	3	hSpCas9	negative selection	10199308
52752175	52752198	3	-	28162770	P31FUJ	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	-0.6355613739147856	[77]	[58]	-5	hSpCas9	negative selection	10199309
52752158	52752181	3	-	28162770	P31FUJ	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-2.014161917939038	[54]	[15]	-8	hSpCas9	negative selection	10199310
52743408	52743431	3	-	28162770	P31FUJ	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	0.7213941059724964	[47]	[92]	8	hSpCas9	negative selection	10199311
52770689	52770712	3	-	28162770	P31FUJ	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-2.4431620702559296	[198]	[42]	-8	hSpCas9	negative selection	10199312
52752277	52752300	3	+	28162770	P31FUJ	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	0.326320291371518	[168]	[248]	3	hSpCas9	negative selection	10199313
52752001	52752024	3	+	28162770	P31FUJ	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.4086474876532509	[383]	[598]	4	hSpCas9	negative selection	10199314
52746838	52746861	3	+	28162770	P31FUJ	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.6335481805348588	[242]	[442]	7	hSpCas9	negative selection	10199315
52770665	52770688	3	-	28162770	TF1	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10368672
52744257	52744280	3	-	28162770	TF1	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	NaN	[NaN]	[169]	1	hSpCas9	negative selection	10368673
52766240	52766263	3	+	28162770	TF1	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	NaN	[NaN]	[207]	1	hSpCas9	negative selection	10368674
52752175	52752198	3	-	28162770	TF1	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	NaN	[NaN]	[9]	1	hSpCas9	negative selection	10368675
52752158	52752181	3	-	28162770	TF1	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10368676
52743408	52743431	3	-	28162770	TF1	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	NaN	[NaN]	[49]	1	hSpCas9	negative selection	10368677
52770689	52770712	3	-	28162770	TF1	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10368678
52752277	52752300	3	+	28162770	TF1	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10368679
52752001	52752024	3	+	28162770	TF1	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	NaN	[NaN]	[535]	1	hSpCas9	negative selection	10368680
52746838	52746861	3	+	28162770	TF1	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	NaN	[NaN]	[193]	1	hSpCas9	negative selection	10368681
52770665	52770688	3	-	28162770	SKM1	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	-0.9263383578367412	[42]	[39]	-6	hSpCas9	negative selection	10538038
52744257	52744280	3	-	28162770	SKM1	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	0.6634251291482361	[39]	[111]	6	hSpCas9	negative selection	10538039
52766240	52766263	3	+	28162770	SKM1	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.495339127369705	[62]	[156]	5	hSpCas9	negative selection	10538040
52752175	52752198	3	-	28162770	SKM1	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	-0.21793037435314488	[24]	[37]	-2	hSpCas9	negative selection	10538041
52752158	52752181	3	-	28162770	SKM1	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	1.1779983019779943	[8]	[35]	9	hSpCas9	negative selection	10538042
52743408	52743431	3	-	28162770	SKM1	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	-0.08503610385579918	[20]	[34]	0	hSpCas9	negative selection	10538043
52770689	52770712	3	-	28162770	SKM1	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-1.9919266994643179	[35]	[15]	-8	hSpCas9	negative selection	10538044
52752277	52752300	3	+	28162770	SKM1	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	0.03597929710556669	[47]	[86]	0	hSpCas9	negative selection	10538045
52752001	52752024	3	+	28162770	SKM1	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	-0.03716979259054087	[82]	[142]	0	hSpCas9	negative selection	10538046
52746838	52746861	3	+	28162770	SKM1	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	-0.11150831521699056	[65]	[107]	-1	hSpCas9	negative selection	10538047
52770665	52770688	3	-	28162770	SKM1	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	-0.9263383578367412	[42]	[39]	-6	hSpCas9	negative selection	10707404
52744257	52744280	3	-	28162770	SKM1	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	0.6634251291482361	[39]	[111]	6	hSpCas9	negative selection	10707405
52766240	52766263	3	+	28162770	SKM1	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.495339127369705	[62]	[156]	5	hSpCas9	negative selection	10707406
52752175	52752198	3	-	28162770	SKM1	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	-0.21793037435314488	[24]	[37]	-2	hSpCas9	negative selection	10707407
52752158	52752181	3	-	28162770	SKM1	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	1.1779983019779943	[8]	[35]	9	hSpCas9	negative selection	10707408
52743408	52743431	3	-	28162770	SKM1	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	-0.08503610385579918	[20]	[34]	0	hSpCas9	negative selection	10707409
52770689	52770712	3	-	28162770	SKM1	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-1.9919266994643179	[35]	[15]	-8	hSpCas9	negative selection	10707410
52752277	52752300	3	+	28162770	SKM1	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	0.03597929710556669	[47]	[86]	0	hSpCas9	negative selection	10707411
52752001	52752024	3	+	28162770	SKM1	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	-0.03716979259054087	[82]	[142]	0	hSpCas9	negative selection	10707412
52746838	52746861	3	+	28162770	SKM1	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	-0.11150831521699056	[65]	[107]	-1	hSpCas9	negative selection	10707413
52770665	52770688	3	-	28162770	PL21	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	-2.0652049520316744	[124]	[12]	-8	hSpCas9	negative selection	10876770
52744257	52744280	3	-	28162770	PL21	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	1.1342516788328632	[111]	[106]	8	hSpCas9	negative selection	10876771
52766240	52766263	3	+	28162770	PL21	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.9236219792919043	[171]	[141]	7	hSpCas9	negative selection	10876772
52752175	52752198	3	-	28162770	PL21	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	-1.384822886231836	[89]	[14]	-7	hSpCas9	negative selection	10876773
52752158	52752181	3	-	28162770	PL21	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-0.2852872126809216	[27]	[9]	-2	hSpCas9	negative selection	10876774
52743408	52743431	3	-	28162770	PL21	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	0.46317402032311406	[64]	[38]	4	hSpCas9	negative selection	10876775
52770689	52770712	3	-	28162770	PL21	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-1.9496075050153618	[141]	[15]	-8	hSpCas9	negative selection	10876776
52752277	52752300	3	+	28162770	PL21	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	-0.5306737526952907	[155]	[46]	-4	hSpCas9	negative selection	10876777
52752001	52752024	3	+	28162770	PL21	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	-0.2459951815345192	[296]	[108]	-2	hSpCas9	negative selection	10876778
52746838	52746861	3	+	28162770	PL21	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.9265745411633566	[219]	[181]	7	hSpCas9	negative selection	10876779
52770665	52770688	3	-	28162770	P31FUJ	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.43512174532217607	[106]	[169]	5	hSpCas9	negative selection	11046136
52744257	52744280	3	-	28162770	P31FUJ	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	-0.023625402582094668	[140]	[162]	0	hSpCas9	negative selection	11046137
52766240	52766263	3	+	28162770	P31FUJ	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.2875302377040646	[174]	[250]	3	hSpCas9	negative selection	11046138
52752175	52752198	3	-	28162770	P31FUJ	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	-0.6355613739147856	[77]	[58]	-5	hSpCas9	negative selection	11046139
52752158	52752181	3	-	28162770	P31FUJ	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-2.014161917939038	[54]	[15]	-8	hSpCas9	negative selection	11046140
52743408	52743431	3	-	28162770	P31FUJ	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	0.7213941059724964	[47]	[92]	8	hSpCas9	negative selection	11046141
52770689	52770712	3	-	28162770	P31FUJ	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-2.4431620702559296	[198]	[42]	-8	hSpCas9	negative selection	11046142
52752277	52752300	3	+	28162770	P31FUJ	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	0.326320291371518	[168]	[248]	3	hSpCas9	negative selection	11046143
52752001	52752024	3	+	28162770	P31FUJ	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.4086474876532509	[383]	[598]	4	hSpCas9	negative selection	11046144
52746838	52746861	3	+	28162770	P31FUJ	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.6335481805348588	[242]	[442]	7	hSpCas9	negative selection	11046145
52770665	52770688	3	-	28162770	OCIAML5	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.9922825586758088	[43]	[157]	8	hSpCas9	negative selection	11215502
52744257	52744280	3	-	28162770	OCIAML5	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	0.42895358044315934	[92]	[225]	3	hSpCas9	negative selection	11215503
52766240	52766263	3	+	28162770	OCIAML5	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.5025277129436877	[130]	[334]	4	hSpCas9	negative selection	11215504
52752175	52752198	3	-	28162770	OCIAML5	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	1.5213918246634477	[32]	[170]	9	hSpCas9	negative selection	11215505
52752158	52752181	3	-	28162770	OCIAML5	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-4.515031583586426	[37]	[2]	-9	hSpCas9	negative selection	11215506
52743408	52743431	3	-	28162770	OCIAML5	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	-1.4709764035084907	[42]	[27]	-7	hSpCas9	negative selection	11215507
52770689	52770712	3	-	28162770	OCIAML5	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-3.9813495878089635	[104]	[11]	-9	hSpCas9	negative selection	11215508
52752277	52752300	3	+	28162770	OCIAML5	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	0.7025222808136404	[111]	[328]	6	hSpCas9	negative selection	11215509
52752001	52752024	3	+	28162770	OCIAML5	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.2614451216730491	[225]	[488]	2	hSpCas9	negative selection	11215510
52746838	52746861	3	+	28162770	OCIAML5	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.7824779587077194	[142]	[443]	7	hSpCas9	negative selection	11215511
52770665	52770688	3	-	28162770	EOL1	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	-0.18978490390846037	[209]	[96]	-1	hSpCas9	negative selection	11384868
52744257	52744280	3	-	28162770	EOL1	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	0.9726420597715796	[176]	[182]	8	hSpCas9	negative selection	11384869
52766240	52766263	3	+	28162770	EOL1	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.30787641112204017	[413]	[269]	3	hSpCas9	negative selection	11384870
52752175	52752198	3	-	28162770	EOL1	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	1.2194526926913507	[96]	[118]	8	hSpCas9	negative selection	11384871
52752158	52752181	3	-	28162770	EOL1	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	1.0153132354937169	[76]	[81]	8	hSpCas9	negative selection	11384872
52743408	52743431	3	-	28162770	EOL1	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	-0.4467080356803961	[118]	[45]	-3	hSpCas9	negative selection	11384873
52770689	52770712	3	-	28162770	EOL1	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-3.925117955345034	[172]	[5]	-9	hSpCas9	negative selection	11384874
52752277	52752300	3	+	28162770	EOL1	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	-0.21517699209607852	[259]	[117]	-2	hSpCas9	negative selection	11384875
52752001	52752024	3	+	28162770	EOL1	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	1.4651161529332375	[384]	[559]	9	hSpCas9	negative selection	11384876
52746838	52746861	3	+	28162770	EOL1	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.874794736373435	[235]	[227]	7	hSpCas9	negative selection	11384877
52770665	52770688	3	-	28162770	MOLM13	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	-0.40180259610969016	[200]	[109]	-2	hSpCas9	negative selection	11554234
52744257	52744280	3	-	28162770	MOLM13	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	0.8407644693210254	[216]	[280]	6	hSpCas9	negative selection	11554235
52766240	52766263	3	+	28162770	MOLM13	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.8318250029535168	[351]	[452]	6	hSpCas9	negative selection	11554236
52752175	52752198	3	-	28162770	MOLM13	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	-0.34534210684969446	[122]	[69]	-2	hSpCas9	negative selection	11554237
52752158	52752181	3	-	28162770	MOLM13	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-1.3221875490811896	[82]	[23]	-6	hSpCas9	negative selection	11554238
52743408	52743431	3	-	28162770	MOLM13	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	0.18990463424481363	[96]	[79]	1	hSpCas9	negative selection	11554239
52770689	52770712	3	-	28162770	MOLM13	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-1.8857475730701214	[229]	[44]	-7	hSpCas9	negative selection	11554240
52752277	52752300	3	+	28162770	MOLM13	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	-0.6873888439333322	[244]	[109]	-4	hSpCas9	negative selection	11554241
52752001	52752024	3	+	28162770	MOLM13	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.7567772146679335	[423]	[517]	6	hSpCas9	negative selection	11554242
52746838	52746861	3	+	28162770	MOLM13	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.3240536089709272	[273]	[247]	2	hSpCas9	negative selection	11554243
52770665	52770688	3	-	28162770	HEL	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.5572207608142999	[138]	[130]	5	hSpCas9	negative selection	11723600
52744257	52744280	3	-	28162770	HEL	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	-0.8868806348770241	[178]	[61]	-5	hSpCas9	negative selection	11723601
52766240	52766263	3	+	28162770	HEL	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	1.2175055656156246	[283]	[422]	9	hSpCas9	negative selection	11723602
52752175	52752198	3	-	28162770	HEL	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	1.231950805722871	[112]	[169]	9	hSpCas9	negative selection	11723603
52752158	52752181	3	-	28162770	HEL	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-5.311457478386518	[61]	[0]	-9	hSpCas9	negative selection	11723604
52743408	52743431	3	-	28162770	HEL	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	-0.194989739100766	[83]	[46]	-1	hSpCas9	negative selection	11723605
52770689	52770712	3	-	28162770	HEL	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-3.588215602839515	[168]	[8]	-9	hSpCas9	negative selection	11723606
52752277	52752300	3	+	28162770	HEL	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	-0.3504399021436291	[210]	[105]	-2	hSpCas9	negative selection	11723607
52752001	52752024	3	+	28162770	HEL	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.6075494035380569	[331]	[323]	5	hSpCas9	negative selection	11723608
52746838	52746861	3	+	28162770	HEL	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.7612123018802126	[221]	[240]	6	hSpCas9	negative selection	11723609
52770665	52770688	3	-	28162770	MV411	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.4056996346995076	[137]	[153]	3	hSpCas9	negative selection	11892966
52744257	52744280	3	-	28162770	MV411	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	0.3983042164094031	[126]	[140]	3	hSpCas9	negative selection	11892967
52766240	52766263	3	+	28162770	MV411	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.3474333407594965	[208]	[223]	3	hSpCas9	negative selection	11892968
52752175	52752198	3	-	28162770	MV411	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	0.37519309798114775	[53]	[58]	3	hSpCas9	negative selection	11892969
52752158	52752181	3	-	28162770	MV411	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-0.13107407247095448	[25]	[19]	-1	hSpCas9	negative selection	11892970
52743408	52743431	3	-	28162770	MV411	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	1.4079022229760212	[50]	[113]	9	hSpCas9	negative selection	11892971
52770689	52770712	3	-	28162770	MV411	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-4.840025290467564	[135]	[3]	-9	hSpCas9	negative selection	11892972
52752277	52752300	3	+	28162770	MV411	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	0.8926351586373015	[171]	[268]	7	hSpCas9	negative selection	11892973
52752001	52752024	3	+	28162770	MV411	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.5905114545416861	[297]	[377]	5	hSpCas9	negative selection	11892974
52746838	52746861	3	+	28162770	MV411	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.7400959471840928	[198]	[279]	6	hSpCas9	negative selection	11892975
52770665	52770688	3	-	28162770	MONOMAC1	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.7908903206398713	[59]	[118]	7	hSpCas9	negative selection	12062332
52744257	52744280	3	-	28162770	MONOMAC1	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	0.011549774751863695	[89]	[103]	0	hSpCas9	negative selection	12062333
52766240	52766263	3	+	28162770	MONOMAC1	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.2655165849423202	[150]	[143]	-2	hSpCas9	negative selection	12062334
52752175	52752198	3	-	28162770	MONOMAC1	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	-0.8394848424414701	[63]	[40]	-6	hSpCas9	negative selection	12062335
52752158	52752181	3	-	28162770	MONOMAC1	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	0.5914590477467345	[21]	[37]	6	hSpCas9	negative selection	12062336
52743408	52743431	3	-	28162770	MONOMAC1	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	-0.6929943417219648	[54]	[38]	-5	hSpCas9	negative selection	12062337
52770689	52770712	3	-	28162770	MONOMAC1	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-1.472671289672981	[91]	[37]	-8	hSpCas9	negative selection	12062338
52752277	52752300	3	+	28162770	MONOMAC1	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	0.31291229924475694	[124]	[177]	3	hSpCas9	negative selection	12062339
52752001	52752024	3	+	28162770	MONOMAC1	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.4504467382196611	[142]	[223]	4	hSpCas9	negative selection	12062340
52746838	52746861	3	+	28162770	MONOMAC1	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.8369104848637839	[146]	[300]	7	hSpCas9	negative selection	12062341
52770665	52770688	3	-	28162770	OCIAML2	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.2074420798704763	[24]	[159]	2	hSpCas9	negative selection	12231698
52744257	52744280	3	-	28162770	OCIAML2	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	0.1381794174333627	[19]	[121]	1	hSpCas9	negative selection	12231699
52766240	52766263	3	+	28162770	OCIAML2	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	-0.07983987220999489	[44]	[235]	0	hSpCas9	negative selection	12231700
52752175	52752198	3	-	28162770	OCIAML2	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	0.06779008954196475	[20]	[121]	0	hSpCas9	negative selection	12231701
52752158	52752181	3	-	28162770	OCIAML2	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	0.0529321308148516	[7]	[45]	0	hSpCas9	negative selection	12231702
52743408	52743431	3	-	28162770	OCIAML2	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	-0.03322451293486295	[11]	[64]	0	hSpCas9	negative selection	12231703
52770689	52770712	3	-	28162770	OCIAML2	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-2.3450989431583023	[32]	[35]	-8	hSpCas9	negative selection	12231704
52752277	52752300	3	+	28162770	OCIAML2	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	0.6554789439076616	[25]	[226]	6	hSpCas9	negative selection	12231705
52752001	52752024	3	+	28162770	OCIAML2	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.014797001928080478	[39]	[223]	0	hSpCas9	negative selection	12231706
52746838	52746861	3	+	28162770	OCIAML2	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.497189769008689	[33]	[265]	5	hSpCas9	negative selection	12231707
52770665	52770688	3	-	28162770	OCIAML3	viability	GACGCTTGTGAAGCACCGGCGGG	NEK4	ENSG00000114904	0.005905201862964393	[31]	[96]	0	hSpCas9	negative selection	12401064
52744257	52744280	3	-	28162770	OCIAML3	viability	GAGGCGACTAAAGCAGTCACAGG	NEK4	ENSG00000114904	1.6357267563534525	[20]	[196]	9	hSpCas9	negative selection	12401065
52766240	52766263	3	+	28162770	OCIAML3	viability	GGGTGCTAGCCATGTCACAGTGG	NEK4	ENSG00000114904	0.37122694151516	[41]	[163]	3	hSpCas9	negative selection	12401066
52752175	52752198	3	-	28162770	OCIAML3	viability	ACATCTTACCTGCAAAAGGGAGG	NEK4	ENSG00000114904	-2.313899721131428	[27]	[16]	-9	hSpCas9	negative selection	12401067
52752158	52752181	3	-	28162770	OCIAML3	viability	GGGAGGGATTCAGTGAGTGATGG	NEK4	ENSG00000114904	-1.0534392589614603	[21]	[31]	-6	hSpCas9	negative selection	12401068
52743408	52743431	3	-	28162770	OCIAML3	viability	AGCAGGGCCAGGAAAACCCCAGG	NEK4	ENSG00000114904	-0.5326070956600202	[22]	[47]	-4	hSpCas9	negative selection	12401069
52770689	52770712	3	-	28162770	OCIAML3	viability	GGGCAAGGGGAGCTATGGAGAGG	NEK4	ENSG00000114904	-3.435309894305105	[42]	[11]	-9	hSpCas9	negative selection	12401070
52752277	52752300	3	+	28162770	OCIAML3	viability	AGGTGACTTCAAGAGACCAGAGG	NEK4	ENSG00000114904	1.4013609109441911	[38]	[310]	9	hSpCas9	negative selection	12401071
52752001	52752024	3	+	28162770	OCIAML3	viability	GACAATGTCAGAGGACCACATGG	NEK4	ENSG00000114904	0.8119847193516735	[79]	[423]	7	hSpCas9	negative selection	12401072
52746838	52746861	3	+	28162770	OCIAML3	viability	TGTGTGGCTGTAAATCTGGGTGG	NEK4	ENSG00000114904	0.004827034978550471	[68]	[208]	0	hSpCas9	negative selection	12401073