Crispr
Gene Info
- Species:Human (Homo sapiens)
- GeneID:137814
- Symbol:NKX2-6
- Description:NK2 homeobox 6
DataSource:
http://genomecrispr.dkfz.de/#!/results/NKX2-6
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| Start | The end | chr | strand | pubmed | cellline | condition | sequence | symbol | ensg | log2fc | rc_initial | rc_final | effect | cas | screentype | index |
23702528 | 23702551 | 8 | - | 26627737 | DLD1 | viability | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.5854842166159686 | [1828] | [1135,864,610] | 6 | hSpCas9 | negative selection | 839132 | 23702544 | 23702567 | 8 | + | 26627737 | DLD1 | viability | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | -0.9084831976031039 | [1675] | [360,300,189] | -7 | hSpCas9 | negative selection | 839133 | 23703010 | 23703033 | 8 | - | 26627737 | DLD1 | viability | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | -0.17180922809877863 | [1243] | [285,247,476] | -2 | hSpCas9 | negative selection | 839134 | 23706343 | 23706366 | 8 | - | 26627737 | DLD1 | viability | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -0.006536482016459955 | [218] | [59,36,100] | 0 | hSpCas9 | negative selection | 839135 | 23706530 | 23706553 | 8 | - | 26627737 | DLD1 | viability | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.3062723122008259 | [615] | [217,251,243] | 3 | hSpCas9 | negative selection | 839136 | 23706551 | 23706574 | 8 | + | 26627737 | DLD1 | viability | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 0.13784325156806454 | [195] | [74,65,61] | 1 | hSpCas9 | negative selection | 839137 | 23702528 | 23702551 | 8 | - | 26627737 | GBM cells | viability after 5 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.4105987683906174 | [699] | [507,489] | 6 | hSpCas9 | negative selection | 921447 | 23702544 | 23702567 | 8 | + | 26627737 | GBM cells | viability after 5 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | -0.086010804652216 | [475] | [272,207] | -1 | hSpCas9 | negative selection | 921448 | 23703010 | 23703033 | 8 | - | 26627737 | GBM cells | viability after 5 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.2777152250288095 | [382] | [194,302] | 4 | hSpCas9 | negative selection | 921449 | 23706343 | 23706366 | 8 | - | 26627737 | GBM cells | viability after 5 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.41516362552282726 | [85] | [65,56] | 6 | hSpCas9 | negative selection | 921450 | 23706530 | 23706553 | 8 | - | 26627737 | GBM cells | viability after 5 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | -0.11548919024128843 | [301] | [129,168] | -2 | hSpCas9 | negative selection | 921451 | 23706551 | 23706574 | 8 | + | 26627737 | GBM cells | viability after 5 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -0.12398652722439318 | [126] | [63,60] | -2 | hSpCas9 | negative selection | 921452 | 23702528 | 23702551 | 8 | - | 26627737 | GBM cells | viability after 13 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.8568329378296036 | [699] | [651,716] | 8 | hSpCas9 | negative selection | 1003762 | 23702544 | 23702567 | 8 | + | 26627737 | GBM cells | viability after 13 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.07154663615313561 | [475] | [309,239] | 0 | hSpCas9 | negative selection | 1003763 | 23703010 | 23703033 | 8 | - | 26627737 | GBM cells | viability after 13 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | -0.10620077608313638 | [382] | [245,149] | -1 | hSpCas9 | negative selection | 1003764 | 23706343 | 23706366 | 8 | - | 26627737 | GBM cells | viability after 13 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -0.02730290849671757 | [85] | [31,56] | 0 | hSpCas9 | negative selection | 1003765 | 23706530 | 23706553 | 8 | - | 26627737 | GBM cells | viability after 13 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.042001971366663005 | [301] | [187,152] | 0 | hSpCas9 | negative selection | 1003766 | 23706551 | 23706574 | 8 | + | 26627737 | GBM cells | viability after 13 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -0.4458515548545976 | [126] | [54,46] | -5 | hSpCas9 | negative selection | 1003767 | 23702528 | 23702551 | 8 | - | 26627737 | GBM cells | viability after 21 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 1.1396373206747512 | [699] | [863,813] | 9 | hSpCas9 | negative selection | 1086077 | 23702544 | 23702567 | 8 | + | 26627737 | GBM cells | viability after 21 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.2199934960922807 | [475] | [319,283] | 2 | hSpCas9 | negative selection | 1086078 | 23703010 | 23703033 | 8 | - | 26627737 | GBM cells | viability after 21 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.04072440544591793 | [382] | [224,203] | 0 | hSpCas9 | negative selection | 1086079 | 23706343 | 23706366 | 8 | - | 26627737 | GBM cells | viability after 21 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.5341050461884628 | [85] | [63,70] | 5 | hSpCas9 | negative selection | 1086080 | 23706530 | 23706553 | 8 | - | 26627737 | GBM cells | viability after 21 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.16747986507031937 | [301] | [177,189] | 1 | hSpCas9 | negative selection | 1086081 | 23706551 | 23706574 | 8 | + | 26627737 | GBM cells | viability after 21 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -0.30453554906567426 | [126] | [58,52] | -3 | hSpCas9 | negative selection | 1086082 | 23702528 | 23702551 | 8 | - | 26627737 | RPE1 | viability after 9 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.24534722532405495 | [2926] | [1228,901] | 1 | hSpCas9 | negative selection | 1168392 | 23702544 | 23702567 | 8 | + | 26627737 | RPE1 | viability after 9 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | -0.009212452258501092 | [1723] | [496,586] | 0 | hSpCas9 | negative selection | 1168393 | 23703010 | 23703033 | 8 | - | 26627737 | RPE1 | viability after 9 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | -0.7258482138411579 | [1938] | [325,419] | -5 | hSpCas9 | negative selection | 1168394 | 23706343 | 23706366 | 8 | - | 26627737 | RPE1 | viability after 9 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -0.4882090639221608 | [455] | [82,125] | -3 | hSpCas9 | negative selection | 1168395 | 23706530 | 23706553 | 8 | - | 26627737 | RPE1 | viability after 9 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.6729961121714548 | [1302] | [473,877] | 4 | hSpCas9 | negative selection | 1168396 | 23706551 | 23706574 | 8 | + | 26627737 | RPE1 | viability after 9 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -0.7840140339810338 | [350] | [65,60] | -5 | hSpCas9 | negative selection | 1168397 | 23702528 | 23702551 | 8 | - | 26627737 | RPE1 | viability after 12 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.076430976236469 | [2926] | [817,840] | 0 | hSpCas9 | negative selection | 1250707 | 23702544 | 23702567 | 8 | + | 26627737 | RPE1 | viability after 12 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | -0.21209179790064947 | [1723] | [360,440] | -1 | hSpCas9 | negative selection | 1250708 | 23703010 | 23703033 | 8 | - | 26627737 | RPE1 | viability after 12 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | -0.40230627991776735 | [1938] | [365,423] | -3 | hSpCas9 | negative selection | 1250709 | 23706343 | 23706366 | 8 | - | 26627737 | RPE1 | viability after 12 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -0.52158009712578 | [455] | [96,72] | -4 | hSpCas9 | negative selection | 1250710 | 23706530 | 23706553 | 8 | - | 26627737 | RPE1 | viability after 12 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.03552612313690229 | [1302] | [300,419] | 0 | hSpCas9 | negative selection | 1250711 | 23706551 | 23706574 | 8 | + | 26627737 | RPE1 | viability after 12 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -1.434651340588986 | [350] | [47,20] | -7 | hSpCas9 | negative selection | 1250712 | 23702528 | 23702551 | 8 | - | 26627737 | RPE1 | viability after 15 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.28506790138182736 | [2926] | [1212,811] | 1 | hSpCas9 | negative selection | 1333022 | 23702544 | 23702567 | 8 | + | 26627737 | RPE1 | viability after 15 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | -0.15113080105519416 | [1723] | [400,475] | -1 | hSpCas9 | negative selection | 1333023 | 23703010 | 23703033 | 8 | - | 26627737 | RPE1 | viability after 15 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | -0.47227656535127016 | [1938] | [289,496] | -3 | hSpCas9 | negative selection | 1333024 | 23706343 | 23706366 | 8 | - | 26627737 | RPE1 | viability after 15 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -0.3366372861610947 | [455] | [121,82] | -2 | hSpCas9 | negative selection | 1333025 | 23706530 | 23706553 | 8 | - | 26627737 | RPE1 | viability after 15 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.17718547433684928 | [1302] | [317,511] | 1 | hSpCas9 | negative selection | 1333026 | 23706551 | 23706574 | 8 | + | 26627737 | RPE1 | viability after 15 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -0.7540366772398386 | [350] | [65,51] | -5 | hSpCas9 | negative selection | 1333027 | 23702528 | 23702551 | 8 | - | 26627737 | RPE1 | viability after 18 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.4476255877401043 | [2926] | [851,1317] | 3 | hSpCas9 | negative selection | 1415337 | 23702544 | 23702567 | 8 | + | 26627737 | RPE1 | viability after 18 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | -0.08657368346266248 | [1723] | [398,479] | 0 | hSpCas9 | negative selection | 1415338 | 23703010 | 23703033 | 8 | - | 26627737 | RPE1 | viability after 18 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | -0.5224512737550207 | [1938] | [372,354] | -3 | hSpCas9 | negative selection | 1415339 | 23706343 | 23706366 | 8 | - | 26627737 | RPE1 | viability after 18 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.5410141385045478 | [455] | [165,192] | 3 | hSpCas9 | negative selection | 1415340 | 23706530 | 23706553 | 8 | - | 26627737 | RPE1 | viability after 18 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.4192328769720267 | [1302] | [563,369] | 2 | hSpCas9 | negative selection | 1415341 | 23706551 | 23706574 | 8 | + | 26627737 | RPE1 | viability after 18 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 0.021154153581943724 | [350] | [157,29] | 0 | hSpCas9 | negative selection | 1415342 | 23702528 | 23702551 | 8 | - | 26627737 | HeLa | viability after 8 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.557798048964 | [975] | [464,909,475] | 5 | hSpCas9 | negative selection | 1497652 | 23702544 | 23702567 | 8 | + | 26627737 | HeLa | viability after 8 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.09678434558914395 | [904] | [568,484,253] | 0 | hSpCas9 | negative selection | 1497653 | 23703010 | 23703033 | 8 | - | 26627737 | HeLa | viability after 8 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.10409854687958608 | [1218] | [836,419,515] | 1 | hSpCas9 | negative selection | 1497654 | 23706343 | 23706366 | 8 | - | 26627737 | HeLa | viability after 8 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.1623556275472462 | [107] | [32,60,58] | 1 | hSpCas9 | negative selection | 1497655 | 23706530 | 23706553 | 8 | - | 26627737 | HeLa | viability after 8 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 1.4492241773425074 | [253] | [391,212,318] | 8 | hSpCas9 | negative selection | 1497656 | 23706551 | 23706574 | 8 | + | 26627737 | HeLa | viability after 8 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 0.23282650998182186 | [127] | [146,26,41] | 2 | hSpCas9 | negative selection | 1497657 | 23702528 | 23702551 | 8 | - | 26627737 | HeLa | viability after 12 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.9023633290915323 | [975] | [900,734,631] | 7 | hSpCas9 | negative selection | 1579967 | 23702544 | 23702567 | 8 | + | 26627737 | HeLa | viability after 12 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.3703654325022503 | [904] | [651,391,420] | 3 | hSpCas9 | negative selection | 1579968 | 23703010 | 23703033 | 8 | - | 26627737 | HeLa | viability after 12 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | -0.3284739639223253 | [1218] | [684,257,283] | -3 | hSpCas9 | negative selection | 1579969 | 23706343 | 23706366 | 8 | - | 26627737 | HeLa | viability after 12 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.8272319193729332 | [107] | [7,149,69] | 6 | hSpCas9 | negative selection | 1579970 | 23706530 | 23706553 | 8 | - | 26627737 | HeLa | viability after 12 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 1.7161412444076212 | [253] | [454,418,155] | 9 | hSpCas9 | negative selection | 1579971 | 23706551 | 23706574 | 8 | + | 26627737 | HeLa | viability after 12 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 0.5732016770332791 | [127] | [14,99,116] | 5 | hSpCas9 | negative selection | 1579972 | 23702528 | 23702551 | 8 | - | 26627737 | HeLa | viability after 15 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.8882053541377972 | [975] | [976,624,589] | 6 | hSpCas9 | negative selection | 1662282 | 23702544 | 23702567 | 8 | + | 26627737 | HeLa | viability after 15 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.1333663140276804 | [904] | [570,357,270] | 1 | hSpCas9 | negative selection | 1662283 | 23703010 | 23703033 | 8 | - | 26627737 | HeLa | viability after 15 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.07970115033310066 | [1218] | [702,500,353] | 0 | hSpCas9 | negative selection | 1662284 | 23706343 | 23706366 | 8 | - | 26627737 | HeLa | viability after 15 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.7055136673662117 | [107] | [130,75,1] | 5 | hSpCas9 | negative selection | 1662285 | 23706530 | 23706553 | 8 | - | 26627737 | HeLa | viability after 15 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 1.2933466487493985 | [253] | [244,242,273] | 8 | hSpCas9 | negative selection | 1662286 | 23706551 | 23706574 | 8 | + | 26627737 | HeLa | viability after 15 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 0.23377404990520523 | [127] | [32,55,97] | 2 | hSpCas9 | negative selection | 1662287 | 23702528 | 23702551 | 8 | - | 26627737 | HeLa | viability after 18 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.9041044565132366 | [975] | [666,522,589] | 6 | hSpCas9 | negative selection | 1744597 | 23702544 | 23702567 | 8 | + | 26627737 | HeLa | viability after 18 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.1587105921387404 | [904] | [390,303,270] | 1 | hSpCas9 | negative selection | 1744598 | 23703010 | 23703033 | 8 | - | 26627737 | HeLa | viability after 18 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.05061197703686271 | [1218] | [455,408,353] | 0 | hSpCas9 | negative selection | 1744599 | 23706343 | 23706366 | 8 | - | 26627737 | HeLa | viability after 18 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.7235987658912459 | [107] | [95,54,1] | 5 | hSpCas9 | negative selection | 1744600 | 23706530 | 23706553 | 8 | - | 26627737 | HeLa | viability after 18 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 1.3321655403081678 | [253] | [177,200,273] | 8 | hSpCas9 | negative selection | 1744601 | 23706551 | 23706574 | 8 | + | 26627737 | HeLa | viability after 18 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 0.179036921492294 | [127] | [17,45,97] | 1 | hSpCas9 | negative selection | 1744602 | 23702528 | 23702551 | 8 | - | 26627737 | HCT116 | viability after 6 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 1.4795090592884046 | [2096] | [1111,812] | 7 | hSpCas9 | negative selection | 1826912 | 23702544 | 23702567 | 8 | + | 26627737 | HCT116 | viability after 6 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.7266750655692058 | [1586] | [330,457] | 4 | hSpCas9 | negative selection | 1826913 | 23703010 | 23703033 | 8 | - | 26627737 | HCT116 | viability after 6 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.11125038232355089 | [1474] | [506,108] | 0 | hSpCas9 | negative selection | 1826914 | 23706343 | 23706366 | 8 | - | 26627737 | HCT116 | viability after 6 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -1.5117522995990278 | [350] | [48,2] | -7 | hSpCas9 | negative selection | 1826915 | 23706530 | 23706553 | 8 | - | 26627737 | HCT116 | viability after 6 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 1.9384776939150776 | [646] | [385,391] | 8 | hSpCas9 | negative selection | 1826916 | 23706551 | 23706574 | 8 | + | 26627737 | HCT116 | viability after 6 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 1.689992417818404 | [369] | [119,224] | 8 | hSpCas9 | negative selection | 1826917 | 23702528 | 23702551 | 8 | - | 26627737 | HCT116 | viability after 8 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.4077440125715015 | [881] | [730,579,624] | 4 | hSpCas9 | negative selection | 1909227 | 23702544 | 23702567 | 8 | + | 26627737 | HCT116 | viability after 8 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.5455379191946998 | [456] | [383,356,361] | 5 | hSpCas9 | negative selection | 1909228 | 23703010 | 23703033 | 8 | - | 26627737 | HCT116 | viability after 8 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | -0.08047882656237393 | [683] | [455,329,285] | -1 | hSpCas9 | negative selection | 1909229 | 23706343 | 23706366 | 8 | - | 26627737 | HCT116 | viability after 8 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.3273453522058307 | [85] | [121,39,17] | 3 | hSpCas9 | negative selection | 1909230 | 23706530 | 23706553 | 8 | - | 26627737 | HCT116 | viability after 8 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.5182589014595375 | [286] | [151,285,239] | 5 | hSpCas9 | negative selection | 1909231 | 23706551 | 23706574 | 8 | + | 26627737 | HCT116 | viability after 8 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -0.9311688402487168 | [221] | [47,65,77] | -8 | hSpCas9 | negative selection | 1909232 | 23702528 | 23702551 | 8 | - | 26627737 | HCT116 | viability after 9 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.5915311967648664 | [2096] | [974,739] | 4 | hSpCas9 | negative selection | 1991542 | 23702544 | 23702567 | 8 | + | 26627737 | HCT116 | viability after 9 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.18781371263860547 | [1586] | [542,434] | 1 | hSpCas9 | negative selection | 1991543 | 23703010 | 23703033 | 8 | - | 26627737 | HCT116 | viability after 9 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | -0.5440681727726814 | [1474] | [206,319] | -4 | hSpCas9 | negative selection | 1991544 | 23706343 | 23706366 | 8 | - | 26627737 | HCT116 | viability after 9 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -1.930068039493983 | [350] | [37,13] | -8 | hSpCas9 | negative selection | 1991545 | 23706530 | 23706553 | 8 | - | 26627737 | HCT116 | viability after 9 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | -0.09230078832012902 | [646] | [151,169] | 0 | hSpCas9 | negative selection | 1991546 | 23706551 | 23706574 | 8 | + | 26627737 | HCT116 | viability after 9 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -0.08555674720013973 | [369] | [134,59] | 0 | hSpCas9 | negative selection | 1991547 | 23702528 | 23702551 | 8 | - | 26627737 | HCT116 | viability after 12 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.5102375963060486 | [881] | [722,535,712] | 5 | hSpCas9 | negative selection | 2073857 | 23702544 | 23702567 | 8 | + | 26627737 | HCT116 | viability after 12 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.8745441447795892 | [456] | [443,536,341] | 7 | hSpCas9 | negative selection | 2073858 | 23703010 | 23703033 | 8 | - | 26627737 | HCT116 | viability after 12 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.2854836843450219 | [683] | [445,410,455] | 3 | hSpCas9 | negative selection | 2073859 | 23706343 | 23706366 | 8 | - | 26627737 | HCT116 | viability after 12 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.02197522509837113 | [85] | [65,49,19] | 0 | hSpCas9 | negative selection | 2073860 | 23706530 | 23706553 | 8 | - | 26627737 | HCT116 | viability after 12 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.8292595710989694 | [286] | [155,317,340] | 7 | hSpCas9 | negative selection | 2073861 | 23706551 | 23706574 | 8 | + | 26627737 | HCT116 | viability after 12 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -0.4282451089707574 | [221] | [51,38,170] | -4 | hSpCas9 | negative selection | 2073862 | 23702528 | 23702551 | 8 | - | 26627737 | HCT116 | viability after 15 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.545724767841953 | [881] | [559,864,770] | 5 | hSpCas9 | negative selection | 2156172 | 23702544 | 23702567 | 8 | + | 26627737 | HCT116 | viability after 15 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.7120627838222668 | [456] | [604,432,274] | 6 | hSpCas9 | negative selection | 2156173 | 23703010 | 23703033 | 8 | - | 26627737 | HCT116 | viability after 15 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.2994219463526264 | [683] | [713,419,345] | 3 | hSpCas9 | negative selection | 2156174 | 23706343 | 23706366 | 8 | - | 26627737 | HCT116 | viability after 15 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.9968777996993504 | [85] | [142,133,24] | 8 | hSpCas9 | negative selection | 2156175 | 23706530 | 23706553 | 8 | - | 26627737 | HCT116 | viability after 15 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.6250267603443949 | [286] | [226,337,194] | 6 | hSpCas9 | negative selection | 2156176 | 23706551 | 23706574 | 8 | + | 26627737 | HCT116 | viability after 15 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -0.5319230076912557 | [221] | [55,64,138] | -5 | hSpCas9 | negative selection | 2156177 | 23702528 | 23702551 | 8 | - | 26627737 | HCT116 | viability after 18 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.8731632974096919 | [881] | [725,658,974] | 7 | hSpCas9 | negative selection | 2238487 | 23702544 | 23702567 | 8 | + | 26627737 | HCT116 | viability after 18 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 1.3867654282925932 | [456] | [533,742,438] | 8 | hSpCas9 | negative selection | 2238488 | 23703010 | 23703033 | 8 | - | 26627737 | HCT116 | viability after 18 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.37901784359189494 | [683] | [468,414,405] | 3 | hSpCas9 | negative selection | 2238489 | 23706343 | 23706366 | 8 | - | 26627737 | HCT116 | viability after 18 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 1.0120626903004224 | [85] | [125,96,24] | 7 | hSpCas9 | negative selection | 2238490 | 23706530 | 23706553 | 8 | - | 26627737 | HCT116 | viability after 18 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.4621547160962893 | [286] | [176,114,290] | 4 | hSpCas9 | negative selection | 2238491 | 23706551 | 23706574 | 8 | + | 26627737 | HCT116 | viability after 18 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -0.3565799200873968 | [221] | [61,53,139] | -3 | hSpCas9 | negative selection | 2238492 | 23706443 | 23706466 | 8 | - | 24336569 | HL60 | viability | GAATGGACGCAGAGCCGCGAGGG | NKX2-6 | ENSG00000180053 | 0.2504743601021485 | [832] | [2096] | 2 | hSpCas9 | negative selection | 2280389 | 23706448 | 23706471 | 8 | + | 24336569 | HL60 | viability | GCGGCTCTGCGTCCATTCTCAGG | NKX2-6 | ENSG00000180053 | -1.1695629666838274 | [708] | [666] | -8 | hSpCas9 | negative selection | 2280390 | 23706460 | 23706483 | 8 | - | 24336569 | HL60 | viability | AAACTTTCAGTACCTGAGAATGG | NKX2-6 | ENSG00000180053 | -0.4711319449937074 | [356] | [544] | -4 | hSpCas9 | negative selection | 2280391 | 23706483 | 23706506 | 8 | + | 24336569 | HL60 | viability | TCCGGGCTCTTCCGCACCCGCGG | NKX2-6 | ENSG00000180053 | 7.26726405360218 | [0] | [325] | 9 | hSpCas9 | negative selection | 2280392 | 23706489 | 23706512 | 8 | + | 24336569 | HL60 | viability | CTCTTCCGCACCCGCGGATGTGG | NKX2-6 | ENSG00000180053 | 0.751827610612334 | [251] | [897] | 6 | hSpCas9 | negative selection | 2280393 | 23706494 | 23706517 | 8 | - | 24336569 | HL60 | viability | CTTCGCCACATCCGCGGGTGCGG | NKX2-6 | ENSG00000180053 | 0.18637729021316873 | [798] | [1923] | 1 | hSpCas9 | negative selection | 2280394 | 23706499 | 23706522 | 8 | - | 24336569 | HL60 | viability | CGCGGCTTCGCCACATCCGCGGG | NKX2-6 | ENSG00000180053 | 0.2898748557192633 | [728] | [1885] | 2 | hSpCas9 | negative selection | 2280395 | 23706529 | 23706552 | 8 | + | 24336569 | HL60 | viability | TCCGCTCGCGCTCCAGTCGCAGG | NKX2-6 | ENSG00000180053 | 1.5400242761173737 | [207] | [1279] | 9 | hSpCas9 | negative selection | 2280396 | 23706541 | 23706564 | 8 | - | 24336569 | HL60 | viability | GGTCAAGGACATCCTGCGACTGG | NKX2-6 | ENSG00000180053 | 0.9446422959661951 | [752] | [3066] | 7 | hSpCas9 | negative selection | 2280397 | 23706548 | 23706571 | 8 | + | 24336569 | HL60 | viability | CAGGATGTCCTTGACCGAGAAGG | NKX2-6 | ENSG00000180053 | -0.22637240560058247 | [292] | [529] | -2 | hSpCas9 | negative selection | 2280398 | 23706443 | 23706466 | 8 | - | 24336569 | KBM7 | viability | GAATGGACGCAGAGCCGCGAGGG | NKX2-6 | ENSG00000180053 | 0.08188819158057004 | [1006] | [2906] | 0 | hSpCas9 | negative selection | 2347566 | 23706448 | 23706471 | 8 | + | 24336569 | KBM7 | viability | GCGGCTCTGCGTCCATTCTCAGG | NKX2-6 | ENSG00000180053 | 1.03346031338042 | [246] | [1378] | 8 | hSpCas9 | negative selection | 2347567 | 23706460 | 23706483 | 8 | - | 24336569 | KBM7 | viability | AAACTTTCAGTACCTGAGAATGG | NKX2-6 | ENSG00000180053 | 0.28867728232121415 | [406] | [1355] | 2 | hSpCas9 | negative selection | 2347568 | 23706483 | 23706506 | 8 | + | 24336569 | KBM7 | viability | TCCGGGCTCTTCCGCACCCGCGG | NKX2-6 | ENSG00000180053 | 0.2497456696282312 | [106] | [346] | 2 | hSpCas9 | negative selection | 2347569 | 23706489 | 23706512 | 8 | + | 24336569 | KBM7 | viability | CTCTTCCGCACCCGCGGATGTGG | NKX2-6 | ENSG00000180053 | 0.2846224030597876 | [272] | [906] | 2 | hSpCas9 | negative selection | 2347570 | 23706494 | 23706517 | 8 | - | 24336569 | KBM7 | viability | CTTCGCCACATCCGCGGGTGCGG | NKX2-6 | ENSG00000180053 | 1.267380453811808 | [326] | [2146] | 8 | hSpCas9 | negative selection | 2347571 | 23706499 | 23706522 | 8 | - | 24336569 | KBM7 | viability | CGCGGCTTCGCCACATCCGCGGG | NKX2-6 | ENSG00000180053 | -0.5781978996293203 | [438] | [801] | -5 | hSpCas9 | negative selection | 2347572 | 23706529 | 23706552 | 8 | + | 24336569 | KBM7 | viability | TCCGCTCGCGCTCCAGTCGCAGG | NKX2-6 | ENSG00000180053 | 0.3839150790941393 | [507] | [1807] | 3 | hSpCas9 | negative selection | 2347573 | 23706541 | 23706564 | 8 | - | 24336569 | KBM7 | viability | GGTCAAGGACATCCTGCGACTGG | NKX2-6 | ENSG00000180053 | 0.6170186701120359 | [938] | [3927] | 5 | hSpCas9 | negative selection | 2347574 | 23706548 | 23706571 | 8 | + | 24336569 | KBM7 | viability | CAGGATGTCCTTGACCGAGAAGG | NKX2-6 | ENSG00000180053 | -0.7557014919112142 | [142] | [230] | -5 | hSpCas9 | negative selection | 2347575 | 23706161 | 23706184 | 8 | + | 27661255 | K562 | viability | GGATGGGAATGGGATTCGAGAGG | NKX2-6 | ENSG00000180053 | 0.026139087121583776 | [839,870] | [743,653] | 0 | dCas9-KRAB | negative selection | 5496706 | 23706448 | 23706471 | 8 | + | 27661255 | K562 | viability | GCGGCTCTGCGTCCATTCTCAGG | NKX2-6 | ENSG00000180053 | 0.39683042512232797 | [472,688] | [654,565] | 9 | dCas9-KRAB | negative selection | 5496707 | 23706551 | 23706574 | 8 | + | 27661255 | K562 | viability | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 0.071155012664045 | [1054,1250] | [1023,913] | 2 | dCas9-KRAB | negative selection | 5496708 | 23702528 | 23702551 | 8 | - | 27869803 | HPAFII | viability after 27 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 1.0705001011215767 | [645] | [661,755,NaN] | 8 | hSpCas9 | negative selection | 9602236 | 23702544 | 23702567 | 8 | + | 27869803 | HPAFII | viability after 27 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.6185276881388806 | [610] | [538,454,NaN] | 5 | hSpCas9 | negative selection | 9602237 | 23703010 | 23703033 | 8 | - | 27869803 | HPAFII | viability after 27 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.04999872459222665 | [463] | [365,157,NaN] | 0 | hSpCas9 | negative selection | 9602238 | 23706343 | 23706366 | 8 | - | 27869803 | HPAFII | viability after 27 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -6.159882386874636 | [135] | [0,0,NaN] | -9 | hSpCas9 | negative selection | 9602239 | 23706530 | 23706553 | 8 | - | 27869803 | HPAFII | viability after 27 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 1.0858269116029406 | [326] | [509,243,NaN] | 8 | hSpCas9 | negative selection | 9602240 | 23706551 | 23706574 | 8 | + | 27869803 | HPAFII | viability after 27 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 0.582304298562097 | [125] | [180,30,NaN] | 5 | hSpCas9 | negative selection | 9602241 | 23702528 | 23702551 | 8 | - | 27869803 | HPAFII | viability after 15 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.7862813949944194 | [645] | [1168,1214,NaN] | 8 | hSpCas9 | negative selection | 9684685 | 23702544 | 23702567 | 8 | + | 27869803 | HPAFII | viability after 15 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.2303505285294909 | [610] | [1024,611,NaN] | 2 | hSpCas9 | negative selection | 9684686 | 23703010 | 23703033 | 8 | - | 27869803 | HPAFII | viability after 15 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.3587256904781735 | [463] | [956,441,NaN] | 4 | hSpCas9 | negative selection | 9684687 | 23706343 | 23706366 | 8 | - | 27869803 | HPAFII | viability after 15 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -2.7684957334458105 | [135] | [26,17,NaN] | -9 | hSpCas9 | negative selection | 9684688 | 23706530 | 23706553 | 8 | - | 27869803 | HPAFII | viability after 15 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.7369831408056453 | [326] | [951,357,NaN] | 7 | hSpCas9 | negative selection | 9684689 | 23706551 | 23706574 | 8 | + | 27869803 | HPAFII | viability after 15 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | -0.045498194334343434 | [125] | [256,52,NaN] | 0 | hSpCas9 | negative selection | 9684690 | 23702528 | 23702551 | 8 | - | 27869803 | ASPC1 | viability after 36 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.18332604600341473 | [1983] | [1590,363,548] | 1 | hSpCas9 | negative selection | 9767134 | 23702544 | 23702567 | 8 | + | 27869803 | ASPC1 | viability after 36 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.19851053866809276 | [1410] | [484,779,444] | 2 | hSpCas9 | negative selection | 9767135 | 23703010 | 23703033 | 8 | - | 27869803 | ASPC1 | viability after 36 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | -0.14544407887290967 | [1401] | [402,461,449] | -1 | hSpCas9 | negative selection | 9767136 | 23706343 | 23706366 | 8 | - | 27869803 | ASPC1 | viability after 36 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -1.354482928015738 | [288] | [83,47,0] | -8 | hSpCas9 | negative selection | 9767137 | 23706530 | 23706553 | 8 | - | 27869803 | ASPC1 | viability after 36 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.970882751874825 | [842] | [774,205,725] | 8 | hSpCas9 | negative selection | 9767138 | 23706551 | 23706574 | 8 | + | 27869803 | ASPC1 | viability after 36 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 0.46115901870302045 | [283] | [285,50,97] | 4 | hSpCas9 | negative selection | 9767139 | 23702528 | 23702551 | 8 | - | 27869803 | PATU8988S | viability after 35 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.6036404620743465 | [1389] | [927,772,NaN] | 6 | hSpCas9 | negative selection | 9849583 | 23702544 | 23702567 | 8 | + | 27869803 | PATU8988S | viability after 35 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | -0.725024000678175 | [1387] | [205,470,NaN] | -6 | hSpCas9 | negative selection | 9849584 | 23703010 | 23703033 | 8 | - | 27869803 | PATU8988S | viability after 35 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.21369528250407388 | [1268] | [455,729,NaN] | 2 | hSpCas9 | negative selection | 9849585 | 23706343 | 23706366 | 8 | - | 27869803 | PATU8988S | viability after 35 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.12826468368337918 | [218] | [53,138,NaN] | 1 | hSpCas9 | negative selection | 9849586 | 23706530 | 23706553 | 8 | - | 27869803 | PATU8988S | viability after 35 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.6690975453872332 | [661] | [400,446,NaN] | 7 | hSpCas9 | negative selection | 9849587 | 23706551 | 23706574 | 8 | + | 27869803 | PATU8988S | viability after 35 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 0.7190485067737181 | [214] | [158,125,NaN] | 7 | hSpCas9 | negative selection | 9849588 | 23702528 | 23702551 | 8 | - | 27869803 | PATU8988S | viability after 31 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 0.670425729182144 | [1389] | [677,1141,NaN] | 7 | hSpCas9 | negative selection | 9932032 | 23702544 | 23702567 | 8 | + | 27869803 | PATU8988S | viability after 31 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | -0.1868997381911175 | [1387] | [322,693,NaN] | -2 | hSpCas9 | negative selection | 9932033 | 23703010 | 23703033 | 8 | - | 27869803 | PATU8988S | viability after 31 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.1853133179547577 | [1268] | [383,818,NaN] | 2 | hSpCas9 | negative selection | 9932034 | 23706343 | 23706366 | 8 | - | 27869803 | PATU8988S | viability after 31 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | 0.5963468435634826 | [218] | [58,224,NaN] | 7 | hSpCas9 | negative selection | 9932035 | 23706530 | 23706553 | 8 | - | 27869803 | PATU8988S | viability after 31 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 0.7202452112317997 | [661] | [422,449,NaN] | 8 | hSpCas9 | negative selection | 9932036 | 23706551 | 23706574 | 8 | + | 27869803 | PATU8988S | viability after 31 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 0.5709718764793872 | [214] | [96,165,NaN] | 6 | hSpCas9 | negative selection | 9932037 | 23702528 | 23702551 | 8 | - | 27869803 | HPAFII | viability after 35 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 1.0377337196777427 | [645] | [653,690,NaN] | 7 | hSpCas9 | negative selection | 10014481 | 23702544 | 23702567 | 8 | + | 27869803 | HPAFII | viability after 35 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.8119418800921896 | [610] | [479,613,NaN] | 5 | hSpCas9 | negative selection | 10014482 | 23703010 | 23703033 | 8 | - | 27869803 | HPAFII | viability after 35 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.7120814381255376 | [463] | [579,164,NaN] | 5 | hSpCas9 | negative selection | 10014483 | 23706343 | 23706366 | 8 | - | 27869803 | HPAFII | viability after 35 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -6.105374288253665 | [135] | [0,0,NaN] | -9 | hSpCas9 | negative selection | 10014484 | 23706530 | 23706553 | 8 | - | 27869803 | HPAFII | viability after 35 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 1.2444078078171434 | [326] | [450,325,NaN] | 8 | hSpCas9 | negative selection | 10014485 | 23706551 | 23706574 | 8 | + | 27869803 | HPAFII | viability after 35 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 1.1089049085216467 | [125] | [233,28,NaN] | 7 | hSpCas9 | negative selection | 10014486 | 23702528 | 23702551 | 8 | - | 27869803 | HPAFII | viability after 31 days | ACACACACCACTGGCCAGCGCGG | NKX2-6 | ENSG00000180053 | 1.2096232388143429 | [645] | [759,923,NaN] | 8 | hSpCas9 | negative selection | 10096930 | 23702544 | 23702567 | 8 | + | 27869803 | HPAFII | viability after 31 days | TGTGTGTGGCGCAGGACCCGAGG | NKX2-6 | ENSG00000180053 | 0.36349146370954655 | [610] | [466,412,NaN] | 2 | hSpCas9 | negative selection | 10096931 | 23703010 | 23703033 | 8 | - | 27869803 | HPAFII | viability after 31 days | GAGCGCGGCGTTGGCAACAGCGG | NKX2-6 | ENSG00000180053 | 0.5156012894802475 | [463] | [422,316,NaN] | 4 | hSpCas9 | negative selection | 10096932 | 23706343 | 23706366 | 8 | - | 27869803 | HPAFII | viability after 31 days | GGCAGTCTTGGAGATGGACGCGG | NKX2-6 | ENSG00000180053 | -6.254091641575082 | [135] | [0,0,NaN] | -9 | hSpCas9 | negative selection | 10096933 | 23706530 | 23706553 | 8 | - | 27869803 | HPAFII | viability after 31 days | TCCTGCGACTGGAGCGCGAGCGG | NKX2-6 | ENSG00000180053 | 1.0604560179389246 | [326] | [510,242,NaN] | 7 | hSpCas9 | negative selection | 10096934 | 23706551 | 23706574 | 8 | + | 27869803 | HPAFII | viability after 31 days | GATGTCCTTGACCGAGAAGGGGG | NKX2-6 | ENSG00000180053 | 1.4297925569567929 | [125] | [346,19,NaN] | 9 | hSpCas9 | negative selection | 10096935 |