| 144399395 | 144399418 | 7 | + | 26627737 | DLD1 | viability | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 1.0093305856325814 | [302] | [62,219,276] | 8 | hSpCas9 | negative selection | 835389 | 144400196 | 144400219 | 7 | - | 26627737 | DLD1 | viability | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | 0.5667273816623875 | [1191] | [499,657,508] | 6 | hSpCas9 | negative selection | 835390 | 144401142 | 144401165 | 7 | + | 26627737 | DLD1 | viability | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.46960904115928204 | [222] | [75,79,127] | 5 | hSpCas9 | negative selection | 835391 | 144403657 | 144403680 | 7 | - | 26627737 | DLD1 | viability | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | -0.9543351643534064 | [182] | [24,52,13] | -7 | hSpCas9 | negative selection | 835392 | 144404583 | 144404606 | 7 | + | 26627737 | DLD1 | viability | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | -0.092011881712739 | [359] | [150,36,122] | -1 | hSpCas9 | negative selection | 835393 | 144410146 | 144410169 | 7 | - | 26627737 | DLD1 | viability | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | -0.022617300765273574 | [386] | [62,160,132] | 0 | hSpCas9 | negative selection | 835394 | 144399395 | 144399418 | 7 | + | 26627737 | GBM cells | viability after 5 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 0.568268562897214 | [248] | [179,215] | 7 | hSpCas9 | negative selection | 917704 | 144400196 | 144400219 | 7 | - | 26627737 | GBM cells | viability after 5 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.3616136753375334 | [919] | [386,380] | -5 | hSpCas9 | negative selection | 917705 | 144401142 | 144401165 | 7 | + | 26627737 | GBM cells | viability after 5 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.23437438307989855 | [190] | [139,100] | 3 | hSpCas9 | negative selection | 917706 | 144403657 | 144403680 | 7 | - | 26627737 | GBM cells | viability after 5 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 1.3049062345615225 | [59] | [86,71] | 9 | hSpCas9 | negative selection | 917707 | 144404583 | 144404606 | 7 | + | 26627737 | GBM cells | viability after 5 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | -0.2011530802182367 | [193] | [83,96] | -3 | hSpCas9 | negative selection | 917708 | 144410146 | 144410169 | 7 | - | 26627737 | GBM cells | viability after 5 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 0.44780712089931995 | [161] | [109,126] | 6 | hSpCas9 | negative selection | 917709 | 144399395 | 144399418 | 7 | + | 26627737 | GBM cells | viability after 13 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 0.4576624711147829 | [248] | [227,150] | 6 | hSpCas9 | negative selection | 1000019 | 144400196 | 144400219 | 7 | - | 26627737 | GBM cells | viability after 13 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.5698702830032139 | [919] | [493,207] | -6 | hSpCas9 | negative selection | 1000020 | 144401142 | 144401165 | 7 | + | 26627737 | GBM cells | viability after 13 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.13942417207780752 | [190] | [133,97] | 1 | hSpCas9 | negative selection | 1000021 | 144403657 | 144403680 | 7 | - | 26627737 | GBM cells | viability after 13 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 1.306656417977489 | [59] | [106,58] | 9 | hSpCas9 | negative selection | 1000022 | 144404583 | 144404606 | 7 | + | 26627737 | GBM cells | viability after 13 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | -0.1631080197300086 | [193] | [109,80] | -2 | hSpCas9 | negative selection | 1000023 | 144410146 | 144410169 | 7 | - | 26627737 | GBM cells | viability after 13 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 0.8679553929788801 | [161] | [171,150] | 8 | hSpCas9 | negative selection | 1000024 | 144399395 | 144399418 | 7 | + | 26627737 | GBM cells | viability after 21 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | -0.22788081030989682 | [248] | [126,104] | -2 | hSpCas9 | negative selection | 1082334 | 144400196 | 144400219 | 7 | - | 26627737 | GBM cells | viability after 21 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -1.1879101003106802 | [919] | [221,216] | -7 | hSpCas9 | negative selection | 1082335 | 144401142 | 144401165 | 7 | + | 26627737 | GBM cells | viability after 21 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.10557212414186207 | [190] | [119,103] | 1 | hSpCas9 | negative selection | 1082336 | 144403657 | 144403680 | 7 | - | 26627737 | GBM cells | viability after 21 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 0.756741151147792 | [59] | [64,45] | 7 | hSpCas9 | negative selection | 1082337 | 144404583 | 144404606 | 7 | + | 26627737 | GBM cells | viability after 21 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.33885342763014153 | [193] | [137,128] | 3 | hSpCas9 | negative selection | 1082338 | 144410146 | 144410169 | 7 | - | 26627737 | GBM cells | viability after 21 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 0.648443042588487 | [161] | [138,136] | 6 | hSpCas9 | negative selection | 1082339 | 144399395 | 144399418 | 7 | + | 26627737 | RPE1 | viability after 9 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 0.9384322071519058 | [694] | [440,385] | 6 | hSpCas9 | negative selection | 1164649 | 144400196 | 144400219 | 7 | - | 26627737 | RPE1 | viability after 9 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.25075869080738666 | [2665] | [628,794] | -2 | hSpCas9 | negative selection | 1164650 | 144401142 | 144401165 | 7 | + | 26627737 | RPE1 | viability after 9 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.5474625556690228 | [513] | [232,237] | 4 | hSpCas9 | negative selection | 1164651 | 144403657 | 144403680 | 7 | - | 26627737 | RPE1 | viability after 9 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 2.3714563556671946 | [93] | [167,131] | 9 | hSpCas9 | negative selection | 1164652 | 144404583 | 144404606 | 7 | + | 26627737 | RPE1 | viability after 9 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.37583653929941074 | [565] | [225,234] | 2 | hSpCas9 | negative selection | 1164653 | 144410146 | 144410169 | 7 | - | 26627737 | RPE1 | viability after 9 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | -1.0269604832325356 | [1415] | [148,305] | -6 | hSpCas9 | negative selection | 1164654 | 144399395 | 144399418 | 7 | + | 26627737 | RPE1 | viability after 12 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 1.095383868670055 | [694] | [414,381] | 6 | hSpCas9 | negative selection | 1246964 | 144400196 | 144400219 | 7 | - | 26627737 | RPE1 | viability after 12 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | 0.21970218528160634 | [2665] | [887,776] | 1 | hSpCas9 | negative selection | 1246965 | 144401142 | 144401165 | 7 | + | 26627737 | RPE1 | viability after 12 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.17747359005750007 | [513] | [127,185] | 1 | hSpCas9 | negative selection | 1246966 | 144403657 | 144403680 | 7 | - | 26627737 | RPE1 | viability after 12 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 1.977940030701635 | [93] | [98,99] | 8 | hSpCas9 | negative selection | 1246967 | 144404583 | 144404606 | 7 | + | 26627737 | RPE1 | viability after 12 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.5202046278877756 | [565] | [186,250] | 3 | hSpCas9 | negative selection | 1246968 | 144410146 | 144410169 | 7 | - | 26627737 | RPE1 | viability after 12 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | -0.8141279419828493 | [1415] | [211,220] | -5 | hSpCas9 | negative selection | 1246969 | 144399395 | 144399418 | 7 | + | 26627737 | RPE1 | viability after 15 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 0.9870545979755696 | [694] | [350,426] | 6 | hSpCas9 | negative selection | 1329279 | 144400196 | 144400219 | 7 | - | 26627737 | RPE1 | viability after 15 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.31971853612033074 | [2665] | [730,481] | -2 | hSpCas9 | negative selection | 1329280 | 144401142 | 144401165 | 7 | + | 26627737 | RPE1 | viability after 15 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.8832483728237223 | [513] | [172,359] | 5 | hSpCas9 | negative selection | 1329281 | 144403657 | 144403680 | 7 | - | 26627737 | RPE1 | viability after 15 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 1.853549823616414 | [93] | [146,46] | 8 | hSpCas9 | negative selection | 1329282 | 144404583 | 144404606 | 7 | + | 26627737 | RPE1 | viability after 15 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.6003038209518452 | [565] | [285,200] | 4 | hSpCas9 | negative selection | 1329283 | 144410146 | 144410169 | 7 | - | 26627737 | RPE1 | viability after 15 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | -0.36761747588329025 | [1415] | [312,307] | -2 | hSpCas9 | negative selection | 1329284 | 144399395 | 144399418 | 7 | + | 26627737 | RPE1 | viability after 18 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 1.1165412547681839 | [694] | [338,478] | 6 | hSpCas9 | negative selection | 1411594 | 144400196 | 144400219 | 7 | - | 26627737 | RPE1 | viability after 18 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.23929356735231466 | [2665] | [463,764] | -1 | hSpCas9 | negative selection | 1411595 | 144401142 | 144401165 | 7 | + | 26627737 | RPE1 | viability after 18 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.5868482880362724 | [513] | [159,259] | 3 | hSpCas9 | negative selection | 1411596 | 144403657 | 144403680 | 7 | - | 26627737 | RPE1 | viability after 18 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 1.910896426595209 | [93] | [135,51] | 8 | hSpCas9 | negative selection | 1411597 | 144404583 | 144404606 | 7 | + | 26627737 | RPE1 | viability after 18 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.3534268957682096 | [565] | [213,174] | 2 | hSpCas9 | negative selection | 1411598 | 144410146 | 144410169 | 7 | - | 26627737 | RPE1 | viability after 18 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | -0.854539191585631 | [1415] | [191,231] | -5 | hSpCas9 | negative selection | 1411599 | 144399395 | 144399418 | 7 | + | 26627737 | HeLa | viability after 8 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | -1.0749433273613413 | [587] | [196,121,65] | -8 | hSpCas9 | negative selection | 1493909 | 144400196 | 144400219 | 7 | - | 26627737 | HeLa | viability after 8 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | 0.16853894233677802 | [993] | [505,518,440] | 1 | hSpCas9 | negative selection | 1493910 | 144401142 | 144401165 | 7 | + | 26627737 | HeLa | viability after 8 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.6907508866873846 | [308] | [279,227,160] | 6 | hSpCas9 | negative selection | 1493911 | 144403657 | 144403680 | 7 | - | 26627737 | HeLa | viability after 8 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | -0.9253197929142387 | [151] | [67,26,17] | -7 | hSpCas9 | negative selection | 1493912 | 144404583 | 144404606 | 7 | + | 26627737 | HeLa | viability after 8 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | -0.6614258656943082 | [382] | [144,76,102] | -6 | hSpCas9 | negative selection | 1493913 | 144410146 | 144410169 | 7 | - | 26627737 | HeLa | viability after 8 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 1.003327475391996 | [220] | [400,42,180] | 7 | hSpCas9 | negative selection | 1493914 | 144399395 | 144399418 | 7 | + | 26627737 | HeLa | viability after 12 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 0.08362271244476627 | [587] | [351,240,183] | 0 | hSpCas9 | negative selection | 1576224 | 144400196 | 144400219 | 7 | - | 26627737 | HeLa | viability after 12 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | 0.232822649215213 | [993] | [406,491,545] | 2 | hSpCas9 | negative selection | 1576225 | 144401142 | 144401165 | 7 | + | 26627737 | HeLa | viability after 12 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | -0.26661814007273293 | [308] | [142,129,43] | -2 | hSpCas9 | negative selection | 1576226 | 144403657 | 144403680 | 7 | - | 26627737 | HeLa | viability after 12 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 0.10865224105131843 | [151] | [117,54,32] | 1 | hSpCas9 | negative selection | 1576227 | 144404583 | 144404606 | 7 | + | 26627737 | HeLa | viability after 12 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | -0.19713867276871572 | [382] | [175,121,118] | -2 | hSpCas9 | negative selection | 1576228 | 144410146 | 144410169 | 7 | - | 26627737 | HeLa | viability after 12 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 0.6555792658403333 | [220] | [36,242,137] | 5 | hSpCas9 | negative selection | 1576229 | 144399395 | 144399418 | 7 | + | 26627737 | HeLa | viability after 15 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | -1.3931804705369135 | [587] | [60,82,132] | -8 | hSpCas9 | negative selection | 1658539 | 144400196 | 144400219 | 7 | - | 26627737 | HeLa | viability after 15 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.19007332747226835 | [993] | [267,517,272] | -2 | hSpCas9 | negative selection | 1658540 | 144401142 | 144401165 | 7 | + | 26627737 | HeLa | viability after 15 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | -0.3167664319425187 | [308] | [81,110,110] | -3 | hSpCas9 | negative selection | 1658541 | 144403657 | 144403680 | 7 | - | 26627737 | HeLa | viability after 15 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 0.014939447981946463 | [151] | [17,48,125] | 0 | hSpCas9 | negative selection | 1658542 | 144404583 | 144404606 | 7 | + | 26627737 | HeLa | viability after 15 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | -0.8638820904682967 | [382] | [138,83,28] | -6 | hSpCas9 | negative selection | 1658543 | 144410146 | 144410169 | 7 | - | 26627737 | HeLa | viability after 15 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 1.0953569844342796 | [220] | [151,126,306] | 7 | hSpCas9 | negative selection | 1658544 | 144399395 | 144399418 | 7 | + | 26627737 | HeLa | viability after 18 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | -1.389197640327747 | [587] | [41,67,132] | -8 | hSpCas9 | negative selection | 1740854 | 144400196 | 144400219 | 7 | - | 26627737 | HeLa | viability after 18 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.2182679887300607 | [993] | [163,431,272] | -2 | hSpCas9 | negative selection | 1740855 | 144401142 | 144401165 | 7 | + | 26627737 | HeLa | viability after 18 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | -0.3032297646306423 | [308] | [51,97,110] | -3 | hSpCas9 | negative selection | 1740856 | 144403657 | 144403680 | 7 | - | 26627737 | HeLa | viability after 18 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | -0.0900479158572931 | [151] | [7,34,125] | -1 | hSpCas9 | negative selection | 1740857 | 144404583 | 144404606 | 7 | + | 26627737 | HeLa | viability after 18 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | -0.8475936907562811 | [382] | [97,65,28] | -6 | hSpCas9 | negative selection | 1740858 | 144410146 | 144410169 | 7 | - | 26627737 | HeLa | viability after 18 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 1.1247088798397211 | [220] | [104,110,306] | 7 | hSpCas9 | negative selection | 1740859 | 144399395 | 144399418 | 7 | + | 26627737 | HCT116 | viability after 6 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | -1.7074199495098399 | [1081] | [73,39] | -7 | hSpCas9 | negative selection | 1823169 | 144400196 | 144400219 | 7 | - | 26627737 | HCT116 | viability after 6 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.08953068256464825 | [2213] | [446,260] | 0 | hSpCas9 | negative selection | 1823170 | 144401142 | 144401165 | 7 | + | 26627737 | HCT116 | viability after 6 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 1.946440729705084 | [353] | [325,152] | 8 | hSpCas9 | negative selection | 1823171 | 144403657 | 144403680 | 7 | - | 26627737 | HCT116 | viability after 6 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 0.2875929110070494 | [212] | [7,58] | 1 | hSpCas9 | negative selection | 1823172 | 144404583 | 144404606 | 7 | + | 26627737 | HCT116 | viability after 6 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.15498928319233118 | [222] | [107,0] | 0 | hSpCas9 | negative selection | 1823173 | 144410146 | 144410169 | 7 | - | 26627737 | HCT116 | viability after 6 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 1.3152808365310686 | [547] | [176,234] | 7 | hSpCas9 | negative selection | 1823174 | 144399395 | 144399418 | 7 | + | 26627737 | HCT116 | viability after 8 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 0.5210726872657365 | [178] | [121,137,163] | 5 | hSpCas9 | negative selection | 1905484 | 144400196 | 144400219 | 7 | - | 26627737 | HCT116 | viability after 8 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | 0.15428906364873796 | [950] | [516,619,610] | 1 | hSpCas9 | negative selection | 1905485 | 144401142 | 144401165 | 7 | + | 26627737 | HCT116 | viability after 8 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | -0.6927311511725294 | [208] | [71,89,51] | -7 | hSpCas9 | negative selection | 1905486 | 144403657 | 144403680 | 7 | - | 26627737 | HCT116 | viability after 8 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 0.6630522766960321 | [72] | [100,47,42] | 6 | hSpCas9 | negative selection | 1905487 | 144404583 | 144404606 | 7 | + | 26627737 | HCT116 | viability after 8 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | -0.18892089257242467 | [242] | [92,144,113] | -2 | hSpCas9 | negative selection | 1905488 | 144410146 | 144410169 | 7 | - | 26627737 | HCT116 | viability after 8 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | -0.9713234080500686 | [601] | [169,202,134] | -8 | hSpCas9 | negative selection | 1905489 | 144399395 | 144399418 | 7 | + | 26627737 | HCT116 | viability after 9 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | -1.8860965011511786 | [1081] | [109,52] | -8 | hSpCas9 | negative selection | 1987799 | 144400196 | 144400219 | 7 | - | 26627737 | HCT116 | viability after 9 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | 0.28517941696651317 | [2213] | [854,613] | 2 | hSpCas9 | negative selection | 1987800 | 144401142 | 144401165 | 7 | + | 26627737 | HCT116 | viability after 9 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 1.054677978161725 | [353] | [192,198] | 7 | hSpCas9 | negative selection | 1987801 | 144403657 | 144403680 | 7 | - | 26627737 | HCT116 | viability after 9 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | -0.710124346681221 | [212] | [36,32] | -5 | hSpCas9 | negative selection | 1987802 | 144404583 | 144404606 | 7 | + | 26627737 | HCT116 | viability after 9 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.5315632065543233 | [222] | [175,14] | 4 | hSpCas9 | negative selection | 1987803 | 144410146 | 144410169 | 7 | - | 26627737 | HCT116 | viability after 9 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 0.9070754531215903 | [547] | [117,397] | 6 | hSpCas9 | negative selection | 1987804 | 144399395 | 144399418 | 7 | + | 26627737 | HCT116 | viability after 12 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 0.24493692160017633 | [178] | [103,107,122] | 2 | hSpCas9 | negative selection | 2070114 | 144400196 | 144400219 | 7 | - | 26627737 | HCT116 | viability after 12 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | 0.0695395932058156 | [950] | [426,609,546] | 0 | hSpCas9 | negative selection | 2070115 | 144401142 | 144401165 | 7 | + | 26627737 | HCT116 | viability after 12 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | -0.8175871580438001 | [208] | [76,75,32] | -7 | hSpCas9 | negative selection | 2070116 | 144403657 | 144403680 | 7 | - | 26627737 | HCT116 | viability after 12 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 1.2199813990462354 | [72] | [148,53,58] | 8 | hSpCas9 | negative selection | 2070117 | 144404583 | 144404606 | 7 | + | 26627737 | HCT116 | viability after 12 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | -0.766423982748696 | [242] | [84,101,37] | -7 | hSpCas9 | negative selection | 2070118 | 144410146 | 144410169 | 7 | - | 26627737 | HCT116 | viability after 12 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | -1.1867248158447639 | [601] | [107,152,158] | -8 | hSpCas9 | negative selection | 2070119 | 144399395 | 144399418 | 7 | + | 26627737 | HCT116 | viability after 15 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 0.09885636058695813 | [178] | [121,122,86] | 1 | hSpCas9 | negative selection | 2152429 | 144400196 | 144400219 | 7 | - | 26627737 | HCT116 | viability after 15 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.0018587027391627764 | [950] | [540,564,529] | 0 | hSpCas9 | negative selection | 2152430 | 144401142 | 144401165 | 7 | + | 26627737 | HCT116 | viability after 15 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | -1.6449267923966013 | [208] | [44,36,33] | -9 | hSpCas9 | negative selection | 2152431 | 144403657 | 144403680 | 7 | - | 26627737 | HCT116 | viability after 15 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 0.7949309450100892 | [72] | [104,32,83] | 7 | hSpCas9 | negative selection | 2152432 | 144404583 | 144404606 | 7 | + | 26627737 | HCT116 | viability after 15 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | -0.0980427755669433 | [242] | [187,148,61] | -1 | hSpCas9 | negative selection | 2152433 | 144410146 | 144410169 | 7 | - | 26627737 | HCT116 | viability after 15 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | -0.36263610629079734 | [601] | [353,192,269] | -4 | hSpCas9 | negative selection | 2152434 | 144399395 | 144399418 | 7 | + | 26627737 | HCT116 | viability after 18 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 0.02137620573238308 | [178] | [105,75,81] | 0 | hSpCas9 | negative selection | 2234744 | 144400196 | 144400219 | 7 | - | 26627737 | HCT116 | viability after 18 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | 0.2573891959590351 | [950] | [375,737,520] | 2 | hSpCas9 | negative selection | 2234745 | 144401142 | 144401165 | 7 | + | 26627737 | HCT116 | viability after 18 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.08556008155974065 | [208] | [38,174,102] | 0 | hSpCas9 | negative selection | 2234746 | 144403657 | 144403680 | 7 | - | 26627737 | HCT116 | viability after 18 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | 0.12556852215009595 | [72] | [43,31,39] | 1 | hSpCas9 | negative selection | 2234747 | 144404583 | 144404606 | 7 | + | 26627737 | HCT116 | viability after 18 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | -0.1341153208878864 | [242] | [125,91,103] | -1 | hSpCas9 | negative selection | 2234748 | 144410146 | 144410169 | 7 | - | 26627737 | HCT116 | viability after 18 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | -0.8617526112124534 | [601] | [162,102,220] | -7 | hSpCas9 | negative selection | 2234749 | 144404632 | 144404655 | 7 | + | 24336569 | HL60 | viability | ATCCGGTACAGTCCACACACAGG | NOBOX | ENSG00000106410 | 0.28728383861129303 | [957] | [2473] | 2 | hSpCas9 | negative selection | 2280569 | 144404641 | 144404664 | 7 | + | 24336569 | HL60 | viability | AGTCCACACACAGGAAATTCAGG | NOBOX | ENSG00000106410 | -0.32282671421259 | [184] | [312] | -3 | hSpCas9 | negative selection | 2280570 | 144404651 | 144404674 | 7 | + | 24336569 | HL60 | viability | CAGGAAATTCAGGTACAGCCAGG | NOBOX | ENSG00000106410 | 0.13468828052571247 | [330] | [768] | 1 | hSpCas9 | negative selection | 2280571 | 144410128 | 144410151 | 7 | + | 24336569 | HL60 | viability | AGGACATGAGCTCACCCTCCTGG | NOBOX | ENSG00000106410 | 1.2080425165660884 | [278] | [1363] | 8 | hSpCas9 | negative selection | 2280572 | 144410142 | 144410165 | 7 | - | 24336569 | HL60 | viability | GATGGCTTCAAAGCCCAGGAGGG | NOBOX | ENSG00000106410 | 0.22224649745908598 | [780] | [1927] | 2 | hSpCas9 | negative selection | 2280573 | 144410153 | 144410176 | 7 | + | 24336569 | HL60 | viability | TTTGAAGCCATCCTTGTCTCTGG | NOBOX | ENSG00000106410 | -0.05781283256425085 | [120] | [245] | 0 | hSpCas9 | negative selection | 2280574 | 144410160 | 144410183 | 7 | - | 24336569 | HL60 | viability | TGGGACACCAGAGACAAGGATGG | NOBOX | ENSG00000106410 | 0.6202409545682149 | [525] | [1710] | 5 | hSpCas9 | negative selection | 2280575 | 144410173 | 144410196 | 7 | + | 24336569 | HL60 | viability | TGGTGTCCCAGGTACCCTCCAGG | NOBOX | ENSG00000106410 | -0.5330695609386442 | [585] | [856] | -5 | hSpCas9 | negative selection | 2280576 | 144410178 | 144410201 | 7 | + | 24336569 | HL60 | viability | TCCCAGGTACCCTCCAGGTCTGG | NOBOX | ENSG00000106410 | 1.8014807993545898 | [161] | [1194] | 9 | hSpCas9 | negative selection | 2280577 | 144410187 | 144410210 | 7 | - | 24336569 | HL60 | viability | CTAACATCACCAGACCTGGAGGG | NOBOX | ENSG00000106410 | 1.0031615813179138 | [508] | [2158] | 7 | hSpCas9 | negative selection | 2280578 | 144404632 | 144404655 | 7 | + | 24336569 | KBM7 | viability | ATCCGGTACAGTCCACACACAGG | NOBOX | ENSG00000106410 | 0.11009251509123907 | [924] | [2722] | 1 | hSpCas9 | negative selection | 2347746 | 144404641 | 144404664 | 7 | + | 24336569 | KBM7 | viability | AGTCCACACACAGGAAATTCAGG | NOBOX | ENSG00000106410 | 1.1694171318119868 | [192] | [1183] | 8 | hSpCas9 | negative selection | 2347747 | 144404651 | 144404674 | 7 | + | 24336569 | KBM7 | viability | CAGGAAATTCAGGTACAGCCAGG | NOBOX | ENSG00000106410 | 0.8008318748147283 | [313] | [1491] | 7 | hSpCas9 | negative selection | 2347748 | 144410128 | 144410151 | 7 | + | 24336569 | KBM7 | viability | AGGACATGAGCTCACCCTCCTGG | NOBOX | ENSG00000106410 | 0.4734325073042888 | [426] | [1616] | 4 | hSpCas9 | negative selection | 2347749 | 144410142 | 144410165 | 7 | - | 24336569 | KBM7 | viability | GATGGCTTCAAAGCCCAGGAGGG | NOBOX | ENSG00000106410 | 0.3427177409459192 | [631] | [2185] | 3 | hSpCas9 | negative selection | 2347750 | 144410153 | 144410176 | 7 | + | 24336569 | KBM7 | viability | TTTGAAGCCATCCTTGTCTCTGG | NOBOX | ENSG00000106410 | 0.4910202587869743 | [47] | [183] | 4 | hSpCas9 | negative selection | 2347751 | 144410160 | 144410183 | 7 | - | 24336569 | KBM7 | viability | TGGGACACCAGAGACAAGGATGG | NOBOX | ENSG00000106410 | 0.8289384386485332 | [354] | [1719] | 7 | hSpCas9 | negative selection | 2347752 | 144410173 | 144410196 | 7 | + | 24336569 | KBM7 | viability | TGGTGTCCCAGGTACCCTCCAGG | NOBOX | ENSG00000106410 | 0.11095517889462858 | [403] | [1189] | 1 | hSpCas9 | negative selection | 2347753 | 144410178 | 144410201 | 7 | + | 24336569 | KBM7 | viability | TCCCAGGTACCCTCCAGGTCTGG | NOBOX | ENSG00000106410 | 0.9007094848753753 | [281] | [1435] | 7 | hSpCas9 | negative selection | 2347754 | 144410187 | 144410210 | 7 | - | 24336569 | KBM7 | viability | CTAACATCACCAGACCTGGAGGG | NOBOX | ENSG00000106410 | -0.1082690234332836 | [725] | [1836] | -1 | hSpCas9 | negative selection | 2347755 | 144404289 | 144404312 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCCAGGCTGGAGTGCAGTGGGGG | NOBOX | ENSG00000106410 | -1.2921060931449064 | [66,2] | [3,0] | -7 | dCas9-VP64 | positive selection | 2435157 | 144404289 | 144404312 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCCAGGCTGGAGTGCAGTGGGGG | NOBOX | ENSG00000106410 | 0.4307409852930557 | [33,0] | [13,0] | 3 | dCas9-VP64 | positive selection | 2530412 | 144403641 | 144403664 | 7 | + | 27661255 | K562 | viability | GGGTCTCCACACTCACCCAGCGG | NOBOX | ENSG00000106410 | -0.05766850770738852 | [1010,939] | [841,670] | -2 | dCas9-KRAB | negative selection | 5496920 | 144403626 | 144403649 | 7 | - | 27661255 | K562 | viability | GGAGACCCCGTCGTGCGAGGGGG | NOBOX | ENSG00000106410 | -0.16331419106170886 | [688,920] | [601,544] | -5 | dCas9-KRAB | negative selection | 5496921 | 144403690 | 144403713 | 7 | - | 27661255 | K562 | viability | GGCGGCGGGAGTCCAGGCCATGG | NOBOX | ENSG00000106410 | 0.22610445789852784 | [611,543] | [558,525] | 7 | dCas9-KRAB | negative selection | 5496922 | 144409951 | 144409974 | 7 | - | 27661255 | K562 | viability | GTACAGACCCAAGATACCAAAGG | NOBOX | ENSG00000106410 | 0.22645367513098466 | [962,770] | [860,772] | 7 | dCas9-KRAB | negative selection | 5496923 | 144410142 | 144410165 | 7 | - | 27661255 | K562 | viability | GATGGCTTCAAAGCCCAGGAGGG | NOBOX | ENSG00000106410 | 0.2114831218799158 | [2235,2442] | [2364,1985] | 7 | dCas9-KRAB | negative selection | 5496924 | 144410224 | 144410247 | 7 | - | 27661255 | K562 | viability | GGAACCTGCTGGCCATGACATGG | NOBOX | ENSG00000106410 | -0.05945222877602341 | [1134,1278] | [1007,850] | -2 | dCas9-KRAB | negative selection | 5496925 | 144399395 | 144399418 | 7 | + | 27869803 | HPAFII | viability after 27 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | -0.3296366248627761 | [323] | [110,155,NaN] | -2 | hSpCas9 | negative selection | 9598493 | 144400196 | 144400219 | 7 | - | 27869803 | HPAFII | viability after 27 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.027470355477528408 | [901] | [257,637,NaN] | 0 | hSpCas9 | negative selection | 9598494 | 144401142 | 144401165 | 7 | + | 27869803 | HPAFII | viability after 27 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 1.2519546841075848 | [149] | [189,185,NaN] | 8 | hSpCas9 | negative selection | 9598495 | 144403657 | 144403680 | 7 | - | 27869803 | HPAFII | viability after 27 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | -0.24387040129756943 | [85] | [5,64,NaN] | -2 | hSpCas9 | negative selection | 9598496 | 144404583 | 144404606 | 7 | + | 27869803 | HPAFII | viability after 27 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.7942166609866925 | [173] | [162,154,NaN] | 6 | hSpCas9 | negative selection | 9598497 | 144410146 | 144410169 | 7 | - | 27869803 | HPAFII | viability after 27 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 0.6429655179563969 | [228] | [139,227,NaN] | 5 | hSpCas9 | negative selection | 9598498 | 144399395 | 144399418 | 7 | + | 27869803 | HPAFII | viability after 15 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | -0.39935292900953445 | [323] | [411,171,NaN] | -4 | hSpCas9 | negative selection | 9680942 | 144400196 | 144400219 | 7 | - | 27869803 | HPAFII | viability after 15 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.06664841495740559 | [901] | [834,981,NaN] | 0 | hSpCas9 | negative selection | 9680943 | 144401142 | 144401165 | 7 | + | 27869803 | HPAFII | viability after 15 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.4807616275145213 | [149] | [203,237,NaN] | 5 | hSpCas9 | negative selection | 9680944 | 144403657 | 144403680 | 7 | - | 27869803 | HPAFII | viability after 15 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | -1.7583646558752697 | [85] | [59,6,NaN] | -9 | hSpCas9 | negative selection | 9680945 | 144404583 | 144404606 | 7 | + | 27869803 | HPAFII | viability after 15 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.5889410360473353 | [173] | [411,199,NaN] | 6 | hSpCas9 | negative selection | 9680946 | 144410146 | 144410169 | 7 | - | 27869803 | HPAFII | viability after 15 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 0.18496658039634495 | [228] | [235,306,NaN] | 2 | hSpCas9 | negative selection | 9680947 | 144399395 | 144399418 | 7 | + | 27869803 | ASPC1 | viability after 36 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 0.2420877276627601 | [451] | [145,182,215] | 2 | hSpCas9 | negative selection | 9763391 | 144400196 | 144400219 | 7 | - | 27869803 | ASPC1 | viability after 36 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | 0.2674491824707683 | [2133] | [1128,1037,611] | 2 | hSpCas9 | negative selection | 9763392 | 144401142 | 144401165 | 7 | + | 27869803 | ASPC1 | viability after 36 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | -0.10966335677390737 | [359] | [174,25,145] | -1 | hSpCas9 | negative selection | 9763393 | 144403657 | 144403680 | 7 | - | 27869803 | ASPC1 | viability after 36 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | -0.07504647363186367 | [226] | [81,65,76] | -1 | hSpCas9 | negative selection | 9763394 | 144404583 | 144404606 | 7 | + | 27869803 | ASPC1 | viability after 36 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.5834438337462814 | [379] | [122,355,124] | 6 | hSpCas9 | negative selection | 9763395 | 144410146 | 144410169 | 7 | - | 27869803 | ASPC1 | viability after 36 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | -0.956952478360633 | [593] | [177,40,107] | -7 | hSpCas9 | negative selection | 9763396 | 144399395 | 144399418 | 7 | + | 27869803 | PATU8988S | viability after 35 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | 0.07045099527324081 | [513] | [161,272,NaN] | 0 | hSpCas9 | negative selection | 9845840 | 144400196 | 144400219 | 7 | - | 27869803 | PATU8988S | viability after 35 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | 0.18026514194970522 | [1881] | [795,921,NaN] | 2 | hSpCas9 | negative selection | 9845841 | 144401142 | 144401165 | 7 | + | 27869803 | PATU8988S | viability after 35 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.23643690907779366 | [405] | [251,132,NaN] | 2 | hSpCas9 | negative selection | 9845842 | 144403657 | 144403680 | 7 | - | 27869803 | PATU8988S | viability after 35 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | -1.1293225059471115 | [249] | [57,33,NaN] | -8 | hSpCas9 | negative selection | 9845843 | 144404583 | 144404606 | 7 | + | 27869803 | PATU8988S | viability after 35 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.17312544164842397 | [359] | [152,173,NaN] | 2 | hSpCas9 | negative selection | 9845844 | 144410146 | 144410169 | 7 | - | 27869803 | PATU8988S | viability after 35 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 0.19582855634073604 | [503] | [230,233,NaN] | 2 | hSpCas9 | negative selection | 9845845 | 144399395 | 144399418 | 7 | + | 27869803 | PATU8988S | viability after 31 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | -0.04816595557331928 | [513] | [122,293,NaN] | 0 | hSpCas9 | negative selection | 9928289 | 144400196 | 144400219 | 7 | - | 27869803 | PATU8988S | viability after 31 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | 0.28768792213224836 | [1881] | [736,1143,NaN] | 3 | hSpCas9 | negative selection | 9928290 | 144401142 | 144401165 | 7 | + | 27869803 | PATU8988S | viability after 31 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 0.5106551697583362 | [405] | [249,205,NaN] | 6 | hSpCas9 | negative selection | 9928291 | 144403657 | 144403680 | 7 | - | 27869803 | PATU8988S | viability after 31 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | -1.5880002396448911 | [249] | [26,40,NaN] | -8 | hSpCas9 | negative selection | 9928292 | 144404583 | 144404606 | 7 | + | 27869803 | PATU8988S | viability after 31 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.13137946565300435 | [359] | [125,196,NaN] | 1 | hSpCas9 | negative selection | 9928293 | 144410146 | 144410169 | 7 | - | 27869803 | PATU8988S | viability after 31 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 0.2606370055146934 | [503] | [238,242,NaN] | 3 | hSpCas9 | negative selection | 9928294 | 144399395 | 144399418 | 7 | + | 27869803 | HPAFII | viability after 35 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | -0.6337734413487464 | [323] | [116,92,NaN] | -4 | hSpCas9 | negative selection | 10010738 | 144400196 | 144400219 | 7 | - | 27869803 | HPAFII | viability after 35 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.255303359009196 | [901] | [113,684,NaN] | -2 | hSpCas9 | negative selection | 10010739 | 144401142 | 144401165 | 7 | + | 27869803 | HPAFII | viability after 35 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 1.3539467350767556 | [149] | [44,361,NaN] | 8 | hSpCas9 | negative selection | 10010740 | 144403657 | 144403680 | 7 | - | 27869803 | HPAFII | viability after 35 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | -0.301110660329053 | [85] | [0,73,NaN] | -2 | hSpCas9 | negative selection | 10010741 | 144404583 | 144404606 | 7 | + | 27869803 | HPAFII | viability after 35 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.9145279627818756 | [173] | [126,209,NaN] | 6 | hSpCas9 | negative selection | 10010742 | 144410146 | 144410169 | 7 | - | 27869803 | HPAFII | viability after 35 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | -0.20569478222227364 | [228] | [92,108,NaN] | -1 | hSpCas9 | negative selection | 10010743 | 144399395 | 144399418 | 7 | + | 27869803 | HPAFII | viability after 31 days | ACCTGGAAAGGTATCCAGAGGGG | NOBOX | ENSG00000106410 | -0.5421791971264251 | [323] | [121,127,NaN] | -4 | hSpCas9 | negative selection | 10093187 | 144400196 | 144400219 | 7 | - | 27869803 | HPAFII | viability after 31 days | CCAGCGCATCATGGTAAAGGGGG | NOBOX | ENSG00000106410 | -0.08775587824658126 | [901] | [148,832,NaN] | 0 | hSpCas9 | negative selection | 10093188 | 144401142 | 144401165 | 7 | + | 27869803 | HPAFII | viability after 31 days | TACTGAGGAGATTGGCCAGGTGG | NOBOX | ENSG00000106410 | 1.0181199972625534 | [149] | [80,267,NaN] | 7 | hSpCas9 | negative selection | 10093189 | 144403657 | 144403680 | 7 | - | 27869803 | HPAFII | viability after 31 days | GAATCCCTGCCAGGGACCGCTGG | NOBOX | ENSG00000106410 | -0.025426335449638904 | [85] | [0,97,NaN] | 0 | hSpCas9 | negative selection | 10093190 | 144404583 | 144404606 | 7 | + | 27869803 | HPAFII | viability after 31 days | GCTGCACCGGATGATGAAGAAGG | NOBOX | ENSG00000106410 | 0.82290995050927 | [173] | [166,178,NaN] | 6 | hSpCas9 | negative selection | 10093191 | 144410146 | 144410169 | 7 | - | 27869803 | HPAFII | viability after 31 days | CAAGGATGGCTTCAAAGCCCAGG | NOBOX | ENSG00000106410 | 0.29592488152710206 | [228] | [96,223,NaN] | 2 | hSpCas9 | negative selection | 10093192 | 144401101 | 144401124 | 7 | - | 28162770 | P31FUJ | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | 0.8139558940959155 | [424] | [877] | 8 | hSpCas9 | negative selection | 10201142 | 144398549 | 144398572 | 7 | + | 28162770 | P31FUJ | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | 0.06802226224721153 | [1211] | [1492] | 0 | hSpCas9 | negative selection | 10201143 | 144410143 | 144410166 | 7 | - | 28162770 | P31FUJ | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | 0.10681181734122625 | [2188] | [2769] | 1 | hSpCas9 | negative selection | 10201144 | 144404653 | 144404676 | 7 | + | 28162770 | P31FUJ | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 0.22350903441375314 | [1093] | [1500] | 2 | hSpCas9 | negative selection | 10201145 | 144401868 | 144401891 | 7 | - | 28162770 | P31FUJ | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | 0.28344754622276336 | [257] | [368] | 3 | hSpCas9 | negative selection | 10201146 | 144401537 | 144401560 | 7 | - | 28162770 | P31FUJ | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | -0.043001600819019714 | [824] | [940] | 0 | hSpCas9 | negative selection | 10201147 | 144401433 | 144401456 | 7 | - | 28162770 | P31FUJ | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | -0.11470407983703668 | [972] | [1055] | -1 | hSpCas9 | negative selection | 10201148 | 144401419 | 144401442 | 7 | + | 28162770 | P31FUJ | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | 0.14810260994531932 | [972] | [1266] | 1 | hSpCas9 | negative selection | 10201149 | 144400227 | 144400250 | 7 | - | 28162770 | P31FUJ | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | -0.11415770791575941 | [699] | [759] | -1 | hSpCas9 | negative selection | 10201150 | 144400162 | 144400185 | 7 | - | 28162770 | P31FUJ | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -1.2728469233097812 | [1241] | [603] | -7 | hSpCas9 | negative selection | 10201151 | 144401101 | 144401124 | 7 | - | 28162770 | TF1 | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | NaN | [NaN] | [122] | 1 | hSpCas9 | negative selection | 10370508 | 144398549 | 144398572 | 7 | + | 28162770 | TF1 | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | NaN | [NaN] | [450] | 1 | hSpCas9 | negative selection | 10370509 | 144410143 | 144410166 | 7 | - | 28162770 | TF1 | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | NaN | [NaN] | [272] | 1 | hSpCas9 | negative selection | 10370510 | 144404653 | 144404676 | 7 | + | 28162770 | TF1 | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | NaN | [NaN] | [234] | 1 | hSpCas9 | negative selection | 10370511 | 144401868 | 144401891 | 7 | - | 28162770 | TF1 | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | NaN | [NaN] | [66] | 1 | hSpCas9 | negative selection | 10370512 | 144401537 | 144401560 | 7 | - | 28162770 | TF1 | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | NaN | [NaN] | [127] | 1 | hSpCas9 | negative selection | 10370513 | 144401433 | 144401456 | 7 | - | 28162770 | TF1 | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | NaN | [NaN] | [49] | 1 | hSpCas9 | negative selection | 10370514 | 144401419 | 144401442 | 7 | + | 28162770 | TF1 | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | NaN | [NaN] | [191] | 1 | hSpCas9 | negative selection | 10370515 | 144400227 | 144400250 | 7 | - | 28162770 | TF1 | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | NaN | [NaN] | [159] | 1 | hSpCas9 | negative selection | 10370516 | 144400162 | 144400185 | 7 | - | 28162770 | TF1 | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | NaN | [NaN] | [49] | 1 | hSpCas9 | negative selection | 10370517 | 144401101 | 144401124 | 7 | - | 28162770 | SKM1 | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | 1.6889602212553738 | [19] | [113] | 9 | hSpCas9 | negative selection | 10539874 | 144398549 | 144398572 | 7 | + | 28162770 | SKM1 | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | -0.06300979752580038 | [90] | [153] | 0 | hSpCas9 | negative selection | 10539875 | 144410143 | 144410166 | 7 | - | 28162770 | SKM1 | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | -0.03831960494876907 | [157] | [271] | 0 | hSpCas9 | negative selection | 10539876 | 144404653 | 144404676 | 7 | + | 28162770 | SKM1 | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 0.7032545565748829 | [73] | [212] | 6 | hSpCas9 | negative selection | 10539877 | 144401868 | 144401891 | 7 | - | 28162770 | SKM1 | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | -0.11150831521699045 | [10] | [17] | -1 | hSpCas9 | negative selection | 10539878 | 144401537 | 144401560 | 7 | - | 28162770 | SKM1 | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | 0.35106301095087405 | [50] | [114] | 3 | hSpCas9 | negative selection | 10539879 | 144401433 | 144401456 | 7 | - | 28162770 | SKM1 | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | 0.04049477822805958 | [65] | [119] | 0 | hSpCas9 | negative selection | 10539880 | 144401419 | 144401442 | 7 | + | 28162770 | SKM1 | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | -0.07693105421874402 | [70] | [118] | 0 | hSpCas9 | negative selection | 10539881 | 144400227 | 144400250 | 7 | - | 28162770 | SKM1 | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | 0.8560702070906322 | [29] | [95] | 7 | hSpCas9 | negative selection | 10539882 | 144400162 | 144400185 | 7 | - | 28162770 | SKM1 | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -1.0933037198393998 | [69] | [57] | -7 | hSpCas9 | negative selection | 10539883 | 144401101 | 144401124 | 7 | - | 28162770 | SKM1 | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | 1.6889602212553738 | [19] | [113] | 9 | hSpCas9 | negative selection | 10709240 | 144398549 | 144398572 | 7 | + | 28162770 | SKM1 | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | -0.06300979752580038 | [90] | [153] | 0 | hSpCas9 | negative selection | 10709241 | 144410143 | 144410166 | 7 | - | 28162770 | SKM1 | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | -0.03831960494876907 | [157] | [271] | 0 | hSpCas9 | negative selection | 10709242 | 144404653 | 144404676 | 7 | + | 28162770 | SKM1 | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 0.7032545565748829 | [73] | [212] | 6 | hSpCas9 | negative selection | 10709243 | 144401868 | 144401891 | 7 | - | 28162770 | SKM1 | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | -0.11150831521699045 | [10] | [17] | -1 | hSpCas9 | negative selection | 10709244 | 144401537 | 144401560 | 7 | - | 28162770 | SKM1 | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | 0.35106301095087405 | [50] | [114] | 3 | hSpCas9 | negative selection | 10709245 | 144401433 | 144401456 | 7 | - | 28162770 | SKM1 | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | 0.04049477822805958 | [65] | [119] | 0 | hSpCas9 | negative selection | 10709246 | 144401419 | 144401442 | 7 | + | 28162770 | SKM1 | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | -0.07693105421874402 | [70] | [118] | 0 | hSpCas9 | negative selection | 10709247 | 144400227 | 144400250 | 7 | - | 28162770 | SKM1 | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | 0.8560702070906322 | [29] | [95] | 7 | hSpCas9 | negative selection | 10709248 | 144400162 | 144400185 | 7 | - | 28162770 | SKM1 | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -1.0933037198393998 | [69] | [57] | -7 | hSpCas9 | negative selection | 10709249 | 144401101 | 144401124 | 7 | - | 28162770 | PL21 | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | -0.6431348818232269 | [121] | [33] | -4 | hSpCas9 | negative selection | 10878606 | 144398549 | 144398572 | 7 | + | 28162770 | PL21 | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | 0.5689540970075182 | [332] | [214] | 5 | hSpCas9 | negative selection | 10878607 | 144410143 | 144410166 | 7 | - | 28162770 | PL21 | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | -0.3101380766315822 | [526] | [184] | -2 | hSpCas9 | negative selection | 10878608 | 144404653 | 144404676 | 7 | + | 28162770 | PL21 | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 0.9627450298136253 | [289] | [245] | 7 | hSpCas9 | negative selection | 10878609 | 144401868 | 144401891 | 7 | - | 28162770 | PL21 | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | 1.4494990834260375 | [52] | [62] | 9 | hSpCas9 | negative selection | 10878610 | 144401537 | 144401560 | 7 | - | 28162770 | PL21 | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | -0.9962575983141835 | [164] | [35] | -6 | hSpCas9 | negative selection | 10878611 | 144401433 | 144401456 | 7 | - | 28162770 | PL21 | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | 0.5027023845097514 | [239] | [147] | 4 | hSpCas9 | negative selection | 10878612 | 144401419 | 144401442 | 7 | + | 28162770 | PL21 | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | -0.6363616532278004 | [224] | [62] | -4 | hSpCas9 | negative selection | 10878613 | 144400227 | 144400250 | 7 | - | 28162770 | PL21 | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | 0.5503259694181959 | [181] | [115] | 5 | hSpCas9 | negative selection | 10878614 | 144400162 | 144400185 | 7 | - | 28162770 | PL21 | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -0.8180077322209393 | [319] | [78] | -5 | hSpCas9 | negative selection | 10878615 | 144401101 | 144401124 | 7 | - | 28162770 | P31FUJ | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | 0.8139558940959155 | [424] | [877] | 8 | hSpCas9 | negative selection | 11047972 | 144398549 | 144398572 | 7 | + | 28162770 | P31FUJ | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | 0.06802226224721153 | [1211] | [1492] | 0 | hSpCas9 | negative selection | 11047973 | 144410143 | 144410166 | 7 | - | 28162770 | P31FUJ | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | 0.10681181734122625 | [2188] | [2769] | 1 | hSpCas9 | negative selection | 11047974 | 144404653 | 144404676 | 7 | + | 28162770 | P31FUJ | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 0.22350903441375314 | [1093] | [1500] | 2 | hSpCas9 | negative selection | 11047975 | 144401868 | 144401891 | 7 | - | 28162770 | P31FUJ | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | 0.28344754622276336 | [257] | [368] | 3 | hSpCas9 | negative selection | 11047976 | 144401537 | 144401560 | 7 | - | 28162770 | P31FUJ | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | -0.043001600819019714 | [824] | [940] | 0 | hSpCas9 | negative selection | 11047977 | 144401433 | 144401456 | 7 | - | 28162770 | P31FUJ | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | -0.11470407983703668 | [972] | [1055] | -1 | hSpCas9 | negative selection | 11047978 | 144401419 | 144401442 | 7 | + | 28162770 | P31FUJ | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | 0.14810260994531932 | [972] | [1266] | 1 | hSpCas9 | negative selection | 11047979 | 144400227 | 144400250 | 7 | - | 28162770 | P31FUJ | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | -0.11415770791575941 | [699] | [759] | -1 | hSpCas9 | negative selection | 11047980 | 144400162 | 144400185 | 7 | - | 28162770 | P31FUJ | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -1.2728469233097812 | [1241] | [603] | -7 | hSpCas9 | negative selection | 11047981 | 144401101 | 144401124 | 7 | - | 28162770 | OCIAML5 | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | 1.2892892783815444 | [33] | [149] | 9 | hSpCas9 | negative selection | 11217338 | 144398549 | 144398572 | 7 | + | 28162770 | OCIAML5 | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | 0.020250876197095313 | [182] | [334] | 0 | hSpCas9 | negative selection | 11217339 | 144410143 | 144410166 | 7 | - | 28162770 | OCIAML5 | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | 0.37982013867124964 | [237] | [558] | 3 | hSpCas9 | negative selection | 11217340 | 144404653 | 144404676 | 7 | + | 28162770 | OCIAML5 | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 1.025449422611008 | [128] | [473] | 8 | hSpCas9 | negative selection | 11217341 | 144401868 | 144401891 | 7 | - | 28162770 | OCIAML5 | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | -1.2443839936427574 | [20] | [15] | -6 | hSpCas9 | negative selection | 11217342 | 144401537 | 144401560 | 7 | - | 28162770 | OCIAML5 | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | -0.659421492921601 | [83] | [95] | -4 | hSpCas9 | negative selection | 11217343 | 144401433 | 144401456 | 7 | - | 28162770 | OCIAML5 | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | 0.03316324188992831 | [84] | [156] | 0 | hSpCas9 | negative selection | 11217344 | 144401419 | 144401442 | 7 | + | 28162770 | OCIAML5 | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | 0.6958338356356143 | [91] | [268] | 6 | hSpCas9 | negative selection | 11217345 | 144400227 | 144400250 | 7 | - | 28162770 | OCIAML5 | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | -0.6628715424913676 | [156] | [178] | -4 | hSpCas9 | negative selection | 11217346 | 144400162 | 144400185 | 7 | - | 28162770 | OCIAML5 | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -1.50657000483823 | [84] | [53] | -7 | hSpCas9 | negative selection | 11217347 | 144401101 | 144401124 | 7 | - | 28162770 | EOL1 | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | 0.5809607955533993 | [150] | [118] | 5 | hSpCas9 | negative selection | 11386704 | 144398549 | 144398572 | 7 | + | 28162770 | EOL1 | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | 1.0523613994485137 | [420] | [459] | 8 | hSpCas9 | negative selection | 11386705 | 144410143 | 144410166 | 7 | - | 28162770 | EOL1 | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | 0.16538643129013253 | [654] | [386] | 1 | hSpCas9 | negative selection | 11386706 | 144404653 | 144404676 | 7 | + | 28162770 | EOL1 | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 0.120520867230685 | [432] | [247] | 1 | hSpCas9 | negative selection | 11386707 | 144401868 | 144401891 | 7 | - | 28162770 | EOL1 | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | -0.9269297037193771 | [82] | [22] | -6 | hSpCas9 | negative selection | 11386708 | 144401537 | 144401560 | 7 | - | 28162770 | EOL1 | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | -0.42204237755109697 | [294] | [115] | -3 | hSpCas9 | negative selection | 11386709 | 144401433 | 144401456 | 7 | - | 28162770 | EOL1 | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | 0.5162676384669994 | [283] | [213] | 5 | hSpCas9 | negative selection | 11386710 | 144401419 | 144401442 | 7 | + | 28162770 | EOL1 | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | -0.06310383600182035 | [348] | [175] | 0 | hSpCas9 | negative selection | 11386711 | 144400227 | 144400250 | 7 | - | 28162770 | EOL1 | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | -0.2427469738271058 | [273] | [121] | -2 | hSpCas9 | negative selection | 11386712 | 144400162 | 144400185 | 7 | - | 28162770 | EOL1 | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -1.5990141844864783 | [390] | [67] | -7 | hSpCas9 | negative selection | 11386713 | 144401101 | 144401124 | 7 | - | 28162770 | MOLM13 | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | 1.2188618337046644 | [122] | [206] | 8 | hSpCas9 | negative selection | 11556070 | 144398549 | 144398572 | 7 | + | 28162770 | MOLM13 | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | 0.8413477770720234 | [395] | [512] | 6 | hSpCas9 | negative selection | 11556071 | 144410143 | 144410166 | 7 | - | 28162770 | MOLM13 | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | -0.4907323772230916 | [652] | [335] | -3 | hSpCas9 | negative selection | 11556072 | 144404653 | 144404676 | 7 | + | 28162770 | MOLM13 | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 0.8748895617580043 | [404] | [536] | 6 | hSpCas9 | negative selection | 11556073 | 144401868 | 144401891 | 7 | - | 28162770 | MOLM13 | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | 1.7019447204066072 | [87] | [206] | 9 | hSpCas9 | negative selection | 11556074 | 144401537 | 144401560 | 7 | - | 28162770 | MOLM13 | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | -0.2510904671482648 | [185] | [112] | -1 | hSpCas9 | negative selection | 11556075 | 144401433 | 144401456 | 7 | - | 28162770 | MOLM13 | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | -0.4748857497624711 | [345] | [179] | -3 | hSpCas9 | negative selection | 11556076 | 144401419 | 144401442 | 7 | + | 28162770 | MOLM13 | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | -0.6419882362277947 | [299] | [138] | -4 | hSpCas9 | negative selection | 11556077 | 144400227 | 144400250 | 7 | - | 28162770 | MOLM13 | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | 0.8732582325853895 | [261] | [346] | 6 | hSpCas9 | negative selection | 11556078 | 144400162 | 144400185 | 7 | - | 28162770 | MOLM13 | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -1.1123966319671041 | [307] | [102] | -5 | hSpCas9 | negative selection | 11556079 | 144401101 | 144401124 | 7 | - | 28162770 | HEL | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | 1.413713318331462 | [108] | [185] | 9 | hSpCas9 | negative selection | 11725436 | 144398549 | 144398572 | 7 | + | 28162770 | HEL | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | 0.11376094105637213 | [416] | [288] | 0 | hSpCas9 | negative selection | 11725437 | 144410143 | 144410166 | 7 | - | 28162770 | HEL | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | 0.6398734983059673 | [503] | [502] | 5 | hSpCas9 | negative selection | 11725438 | 144404653 | 144404676 | 7 | + | 28162770 | HEL | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 0.5332404670698425 | [300] | [278] | 4 | hSpCas9 | negative selection | 11725439 | 144401868 | 144401891 | 7 | - | 28162770 | HEL | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | 0.3742499960744552 | [52] | [43] | 3 | hSpCas9 | negative selection | 11725440 | 144401537 | 144401560 | 7 | - | 28162770 | HEL | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | 0.7024450781246249 | [212] | [221] | 6 | hSpCas9 | negative selection | 11725441 | 144401433 | 144401456 | 7 | - | 28162770 | HEL | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | 0.8536847266856967 | [234] | [271] | 7 | hSpCas9 | negative selection | 11725442 | 144401419 | 144401442 | 7 | + | 28162770 | HEL | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | 0.28816597398540766 | [256] | [200] | 2 | hSpCas9 | negative selection | 11725443 | 144400227 | 144400250 | 7 | - | 28162770 | HEL | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | 0.6222747294406413 | [212] | [209] | 5 | hSpCas9 | negative selection | 11725444 | 144400162 | 144400185 | 7 | - | 28162770 | HEL | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -0.7220978543562963 | [272] | [105] | -5 | hSpCas9 | negative selection | 11725445 | 144401101 | 144401124 | 7 | - | 28162770 | MV411 | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | 0.9559747366224641 | [81] | [133] | 8 | hSpCas9 | negative selection | 11894802 | 144398549 | 144398572 | 7 | + | 28162770 | MV411 | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | 0.864887904252836 | [321] | [493] | 7 | hSpCas9 | negative selection | 11894803 | 144410143 | 144410166 | 7 | - | 28162770 | MV411 | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | -0.4494387557679198 | [555] | [342] | -3 | hSpCas9 | negative selection | 11894804 | 144404653 | 144404676 | 7 | + | 28162770 | MV411 | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 0.31823332889263545 | [337] | [354] | 3 | hSpCas9 | negative selection | 11894805 | 144401868 | 144401891 | 7 | - | 28162770 | MV411 | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | -0.8196766450757615 | [43] | [20] | -5 | hSpCas9 | negative selection | 11894806 | 144401537 | 144401560 | 7 | - | 28162770 | MV411 | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | 0.1495902273846308 | [182] | [170] | 1 | hSpCas9 | negative selection | 11894807 | 144401433 | 144401456 | 7 | - | 28162770 | MV411 | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | -0.015596855051018654 | [203] | [169] | 0 | hSpCas9 | negative selection | 11894808 | 144401419 | 144401442 | 7 | + | 28162770 | MV411 | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | -0.1285780596668843 | [230] | [177] | -1 | hSpCas9 | negative selection | 11894809 | 144400227 | 144400250 | 7 | - | 28162770 | MV411 | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | 0.9786207923549755 | [149] | [248] | 8 | hSpCas9 | negative selection | 11894810 | 144400162 | 144400185 | 7 | - | 28162770 | MV411 | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -2.074490544104587 | [264] | [52] | -8 | hSpCas9 | negative selection | 11894811 | 144401101 | 144401124 | 7 | - | 28162770 | MONOMAC1 | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | 1.5969596921430316 | [61] | [214] | 9 | hSpCas9 | negative selection | 12064168 | 144398549 | 144398572 | 7 | + | 28162770 | MONOMAC1 | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | 0.04076026727521742 | [172] | [203] | 0 | hSpCas9 | negative selection | 12064169 | 144410143 | 144410166 | 7 | - | 28162770 | MONOMAC1 | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | 0.42789206097924715 | [355] | [548] | 4 | hSpCas9 | negative selection | 12064170 | 144404653 | 144404676 | 7 | + | 28162770 | MONOMAC1 | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 1.2756594214106904 | [186] | [518] | 9 | hSpCas9 | negative selection | 12064171 | 144401868 | 144401891 | 7 | - | 28162770 | MONOMAC1 | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | 0.3568987580409779 | [46] | [68] | 3 | hSpCas9 | negative selection | 12064172 | 144401537 | 144401560 | 7 | - | 28162770 | MONOMAC1 | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | 0.45604067858621467 | [130] | [205] | 4 | hSpCas9 | negative selection | 12064173 | 144401433 | 144401456 | 7 | - | 28162770 | MONOMAC1 | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | 0.1822506272700882 | [142] | [185] | 1 | hSpCas9 | negative selection | 12064174 | 144401419 | 144401442 | 7 | + | 28162770 | MONOMAC1 | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | 0.1753810182815018 | [145] | [188] | 1 | hSpCas9 | negative selection | 12064175 | 144400227 | 144400250 | 7 | - | 28162770 | MONOMAC1 | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | 0.6399048709864006 | [130] | [233] | 6 | hSpCas9 | negative selection | 12064176 | 144400162 | 144400185 | 7 | - | 28162770 | MONOMAC1 | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -0.7999658943101589 | [201] | [132] | -6 | hSpCas9 | negative selection | 12064177 | 144401101 | 144401124 | 7 | - | 28162770 | OCIAML2 | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | -0.035243680571514835 | [21] | [118] | 0 | hSpCas9 | negative selection | 12233534 | 144398549 | 144398572 | 7 | + | 28162770 | OCIAML2 | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | 0.192335187480268 | [65] | [417] | 1 | hSpCas9 | negative selection | 12233535 | 144410143 | 144410166 | 7 | - | 28162770 | OCIAML2 | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | -0.21116581730145256 | [117] | [564] | -2 | hSpCas9 | negative selection | 12233536 | 144404653 | 144404676 | 7 | + | 28162770 | OCIAML2 | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 0.6622644452551842 | [56] | [499] | 6 | hSpCas9 | negative selection | 12233537 | 144401868 | 144401891 | 7 | - | 28162770 | OCIAML2 | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | 0.851298269645201 | [6] | [69] | 7 | hSpCas9 | negative selection | 12233538 | 144401537 | 144401560 | 7 | - | 28162770 | OCIAML2 | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | 0.2465272878438647 | [32] | [216] | 2 | hSpCas9 | negative selection | 12233539 | 144401433 | 144401456 | 7 | - | 28162770 | OCIAML2 | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | -0.6087059606451338 | [62] | [228] | -4 | hSpCas9 | negative selection | 12233540 | 144401419 | 144401442 | 7 | + | 28162770 | OCIAML2 | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | -0.4037983167639525 | [57] | [242] | -3 | hSpCas9 | negative selection | 12233541 | 144400227 | 144400250 | 7 | - | 28162770 | OCIAML2 | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | 0.271572417290192 | [54] | [367] | 2 | hSpCas9 | negative selection | 12233542 | 144400162 | 144400185 | 7 | - | 28162770 | OCIAML2 | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -1.5179355400205177 | [61] | [119] | -7 | hSpCas9 | negative selection | 12233543 | 144401101 | 144401124 | 7 | - | 28162770 | OCIAML3 | viability | AAAACAGAGACCACAAGCAGGGG | NOBOX | ENSG00000106410 | 0.6637901171434833 | [22] | [109] | 6 | hSpCas9 | negative selection | 12402900 | 144398549 | 144398572 | 7 | + | 28162770 | OCIAML3 | viability | GCTCCTCCAAATATGAACAGGGG | NOBOX | ENSG00000106410 | 0.5924054839067181 | [57] | [263] | 5 | hSpCas9 | negative selection | 12402901 | 144410143 | 144410166 | 7 | - | 28162770 | OCIAML3 | viability | GGATGGCTTCAAAGCCCAGGAGG | NOBOX | ENSG00000106410 | 0.6483531972448806 | [122] | [581] | 6 | hSpCas9 | negative selection | 12402902 | 144404653 | 144404676 | 7 | + | 28162770 | OCIAML3 | viability | GGAAATTCAGGTACAGCCAGGGG | NOBOX | ENSG00000106410 | 0.5498281322494882 | [61] | [273] | 5 | hSpCas9 | negative selection | 12402903 | 144401868 | 144401891 | 7 | - | 28162770 | OCIAML3 | viability | GGGAAAAGGGAACTCACAAGGGG | NOBOX | ENSG00000106410 | -0.009045139603007346 | [9] | [29] | 0 | hSpCas9 | negative selection | 12402904 | 144401537 | 144401560 | 7 | - | 28162770 | OCIAML3 | viability | GGGGAGGAGGAACTGCTCCGGGG | NOBOX | ENSG00000106410 | 0.39088546728562845 | [47] | [189] | 3 | hSpCas9 | negative selection | 12402905 | 144401433 | 144401456 | 7 | - | 28162770 | OCIAML3 | viability | AGTCTCTGGAGAAGCCACCGGGG | NOBOX | ENSG00000106410 | 0.5083540773055145 | [50] | [218] | 5 | hSpCas9 | negative selection | 12402906 | 144401419 | 144401442 | 7 | + | 28162770 | OCIAML3 | viability | TCTCCCAGCATCAGCCCCGGTGG | NOBOX | ENSG00000106410 | 0.23680625455742985 | [60] | [216] | 2 | hSpCas9 | negative selection | 12402907 | 144400227 | 144400250 | 7 | - | 28162770 | OCIAML3 | viability | GAGAGATTGCCCAGACGGTGGGG | NOBOX | ENSG00000106410 | 0.31013234426832076 | [34] | [130] | 3 | hSpCas9 | negative selection | 12402908 | 144400162 | 144400185 | 7 | - | 28162770 | OCIAML3 | viability | GTGGCAGGGTGGAGTGGCGGAGG | NOBOX | ENSG00000106410 | -1.4218266649414828 | [70] | [79] | -7 | hSpCas9 | negative selection | 12402909 |