Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:29959
• Symbol:NRBP1
• Description:nuclear receptor binding protein 1

DataSource: http://genomecrispr.dkfz.de/#!/results/NRBP1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
27433367	27433390	2	-	26472758	Jiyoye	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-1.7575693808307589	[138]	[30]	-8	hSpCas9	negative selection	111284
27434069	27434092	2	+	26472758	Jiyoye	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-0.3297902126603329	[64]	[38]	-2	hSpCas9	negative selection	111285
27433774	27433797	2	+	26472758	Jiyoye	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	-1.0704740950726488	[258]	[92]	-6	hSpCas9	negative selection	111286
27437307	27437330	2	-	26472758	Jiyoye	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-1.1349740356763096	[165]	[56]	-6	hSpCas9	negative selection	111287
27439853	27439876	2	-	26472758	Jiyoye	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-2.3498478650015864	[168]	[24]	-8	hSpCas9	negative selection	111288
27439876	27439899	2	-	26472758	Jiyoye	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	0.4843432420283331	[181]	[191]	3	hSpCas9	negative selection	111289
27440847	27440870	2	+	26472758	Jiyoye	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	-0.18343368235642493	[127]	[84]	-1	hSpCas9	negative selection	111290
27441138	27441161	2	+	26472758	Jiyoye	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	0.20827131309179509	[131]	[114]	1	hSpCas9	negative selection	111291
27433289	27433312	2	+	26472758	Jiyoye	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.05848819084293844	[231]	[167]	0	hSpCas9	negative selection	111292
27433708	27433731	2	+	26472758	Jiyoye	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-1.14031241379662	[37]	[12]	-7	hSpCas9	negative selection	111293
27433367	27433390	2	-	26472758	KBM7	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-1.9122921804187256	[468,355]	[49,51]	-8	hSpCas9	negative selection	302402
27434069	27434092	2	+	26472758	KBM7	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	0.13451974608848383	[470,506]	[139,356]	1	hSpCas9	negative selection	302403
27433774	27433797	2	+	26472758	KBM7	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	-0.2666322767627608	[785,584]	[298,234]	-3	hSpCas9	negative selection	302404
27437307	27437330	2	-	26472758	KBM7	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-2.013857679991859	[600,510]	[35,89]	-8	hSpCas9	negative selection	302405
27439853	27439876	2	-	26472758	KBM7	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-1.2128094976887007	[366,210]	[98,19]	-7	hSpCas9	negative selection	302406
27439876	27439899	2	-	26472758	KBM7	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-0.14352719186134255	[1416,1107]	[593,478]	-1	hSpCas9	negative selection	302407
27440847	27440870	2	+	26472758	KBM7	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.2296804616026093	[621,490]	[377,238]	2	hSpCas9	negative selection	302408
27441138	27441161	2	+	26472758	KBM7	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-0.4670451174855113	[728,760]	[307,207]	-4	hSpCas9	negative selection	302409
27433289	27433312	2	+	26472758	KBM7	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.10920962721763572	[1403,1519]	[614,667]	-1	hSpCas9	negative selection	302410
27433708	27433731	2	+	26472758	KBM7	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-1.4997896416199321	[166,319]	[13,66]	-8	hSpCas9	negative selection	302411
27433367	27433390	2	-	26472758	Raji	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-3.0080936820463364	[207]	[5]	-9	hSpCas9	negative selection	493520
27434069	27434092	2	+	26472758	Raji	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-1.4721038352814055	[262]	[21]	-7	hSpCas9	negative selection	493521
27433774	27433797	2	+	26472758	Raji	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	-1.5778430888209856	[282]	[21]	-8	hSpCas9	negative selection	493522
27437307	27437330	2	-	26472758	Raji	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-1.9603610712622346	[217]	[12]	-8	hSpCas9	negative selection	493523
27439853	27439876	2	-	26472758	Raji	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.7093092512633407	[154]	[21]	-5	hSpCas9	negative selection	493524
27439876	27439899	2	-	26472758	Raji	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-0.6456168572456037	[572]	[84]	-5	hSpCas9	negative selection	493525
27440847	27440870	2	+	26472758	Raji	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	-0.10143047946230763	[281]	[60]	-1	hSpCas9	negative selection	493526
27441138	27441161	2	+	26472758	Raji	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-1.651608365122606	[351]	[25]	-8	hSpCas9	negative selection	493527
27433289	27433312	2	+	26472758	Raji	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.4604547875563476	[669]	[112]	-4	hSpCas9	negative selection	493528
27433708	27433731	2	+	26472758	Raji	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-2.7914697411695006	[178]	[5]	-9	hSpCas9	negative selection	493529
27433367	27433390	2	-	26472758	K562	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-3.6111913629983787	[303]	[20]	-9	hSpCas9	negative selection	684638
27434069	27434092	2	+	26472758	K562	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-1.910555932309894	[431]	[96]	-7	hSpCas9	negative selection	684639
27433774	27433797	2	+	26472758	K562	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	-0.9770614615555799	[526]	[225]	-5	hSpCas9	negative selection	684640
27437307	27437330	2	-	26472758	K562	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-2.4772801098464488	[375]	[56]	-8	hSpCas9	negative selection	684641
27439853	27439876	2	-	26472758	K562	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-4.45096776274836	[284]	[10]	-9	hSpCas9	negative selection	684642
27439876	27439899	2	-	26472758	K562	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-1.8700538274281469	[956]	[220]	-7	hSpCas9	negative selection	684643
27440847	27440870	2	+	26472758	K562	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.5803052801437287	[575]	[726]	5	hSpCas9	negative selection	684644
27441138	27441161	2	+	26472758	K562	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-1.06834105194732	[548]	[220]	-5	hSpCas9	negative selection	684645
27433289	27433312	2	+	26472758	K562	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.745597183760931	[1151]	[579]	-4	hSpCas9	negative selection	684646
27433708	27433731	2	+	26472758	K562	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-2.0051951624050255	[213]	[44]	-7	hSpCas9	negative selection	684647
27433263	27433286	2	+	26627737	DLD1	viability	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-1.0754390546313606	[738]	[186,96,52]	-7	hSpCas9	negative selection	811575
27433711	27433734	2	-	26627737	DLD1	viability	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.46243098791283793	[460]	[96,76,133]	-5	hSpCas9	negative selection	811576
27437291	27437314	2	+	26627737	DLD1	viability	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-1.1826742812345021	[207]	[12,46,26]	-8	hSpCas9	negative selection	811577
27439853	27439876	2	-	26627737	DLD1	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-1.391580434088437	[646]	[152,39,41]	-8	hSpCas9	negative selection	811578
27440917	27440940	2	-	26627737	DLD1	viability	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.9964866477499317	[482]	[94,77,56]	-7	hSpCas9	negative selection	811579
27441144	27441167	2	+	26627737	DLD1	viability	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.6067778194055815	[987]	[193,183,225]	-5	hSpCas9	negative selection	811580
27433263	27433286	2	+	26627737	GBM cells	viability after 5 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.2984228983814321	[351]	[174,131]	-5	hSpCas9	negative selection	893890
27433711	27433734	2	-	26627737	GBM cells	viability after 5 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.44212304294938143	[208]	[76,87]	-6	hSpCas9	negative selection	893891
27437291	27437314	2	+	26627737	GBM cells	viability after 5 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	0.32272158379226146	[81]	[35,73]	5	hSpCas9	negative selection	893892
27439853	27439876	2	-	26627737	GBM cells	viability after 5 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-1.953790034346792	[306]	[53,30]	-9	hSpCas9	negative selection	893893
27440917	27440940	2	-	26627737	GBM cells	viability after 5 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.647375107889721	[174]	[183,109]	8	hSpCas9	negative selection	893894
27441144	27441167	2	+	26627737	GBM cells	viability after 5 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	0.0766372468884054	[327]	[133,236]	1	hSpCas9	negative selection	893895
27433263	27433286	2	+	26627737	GBM cells	viability after 13 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.2812220328449093	[351]	[208,114]	-3	hSpCas9	negative selection	976205
27433711	27433734	2	-	26627737	GBM cells	viability after 13 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.5284747275096968	[208]	[71,83]	-6	hSpCas9	negative selection	976206
27437291	27437314	2	+	26627737	GBM cells	viability after 13 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	0.22417460226164132	[81]	[62,42]	3	hSpCas9	negative selection	976207
27439853	27439876	2	-	26627737	GBM cells	viability after 13 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-2.0607180803503473	[306]	[29,47]	-9	hSpCas9	negative selection	976208
27440917	27440940	2	-	26627737	GBM cells	viability after 13 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.6387676424214064	[174]	[170,128]	7	hSpCas9	negative selection	976209
27441144	27441167	2	+	26627737	GBM cells	viability after 13 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.5840225459284021	[327]	[110,124]	-6	hSpCas9	negative selection	976210
27433263	27433286	2	+	26627737	GBM cells	viability after 21 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-1.1029246539950477	[351]	[99,78]	-7	hSpCas9	negative selection	1058520
27433711	27433734	2	-	26627737	GBM cells	viability after 21 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.13286468925325648	[208]	[113,93]	-1	hSpCas9	negative selection	1058521
27437291	27437314	2	+	26627737	GBM cells	viability after 21 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-0.1634279291804812	[81]	[44,34]	-1	hSpCas9	negative selection	1058522
27439853	27439876	2	-	26627737	GBM cells	viability after 21 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-2.4664468778394637	[306]	[25,33]	-9	hSpCas9	negative selection	1058523
27440917	27440940	2	-	26627737	GBM cells	viability after 21 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.9791703977327884	[174]	[200,174]	8	hSpCas9	negative selection	1058524
27441144	27441167	2	+	26627737	GBM cells	viability after 21 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.20720510595000818	[327]	[145,161]	-2	hSpCas9	negative selection	1058525
27433263	27433286	2	+	26627737	RPE1	viability after 9 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	0.15290436003469865	[975]	[261,439]	1	hSpCas9	negative selection	1140835
27433711	27433734	2	-	26627737	RPE1	viability after 9 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-1.4174071037826872	[894]	[24,207]	-7	hSpCas9	negative selection	1140836
27437291	27437314	2	+	26627737	RPE1	viability after 9 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-0.7947828562887134	[560]	[95,107]	-5	hSpCas9	negative selection	1140837
27439853	27439876	2	-	26627737	RPE1	viability after 9 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.7183132713936589	[1116]	[143,300]	-5	hSpCas9	negative selection	1140838
27440917	27440940	2	-	26627737	RPE1	viability after 9 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.19082139290626998	[896]	[306,337]	1	hSpCas9	negative selection	1140839
27441144	27441167	2	+	26627737	RPE1	viability after 9 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	0.14345431468227224	[820]	[296,266]	1	hSpCas9	negative selection	1140840
27433263	27433286	2	+	26627737	RPE1	viability after 12 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.40131927729214545	[975]	[182,214]	-3	hSpCas9	negative selection	1223150
27433711	27433734	2	-	26627737	RPE1	viability after 12 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.3950592876487227	[894]	[92,277]	-3	hSpCas9	negative selection	1223151
27437291	27437314	2	+	26627737	RPE1	viability after 12 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-1.2669964829200948	[560]	[66,57]	-7	hSpCas9	negative selection	1223152
27439853	27439876	2	-	26627737	RPE1	viability after 12 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.6242988436587971	[1116]	[166,223]	-4	hSpCas9	negative selection	1223153
27440917	27440940	2	-	26627737	RPE1	viability after 12 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.03353208439407751	[896]	[267,200]	0	hSpCas9	negative selection	1223154
27441144	27441167	2	+	26627737	RPE1	viability after 12 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	0.3672302830164158	[820]	[318,247]	2	hSpCas9	negative selection	1223155
27433263	27433286	2	+	26627737	RPE1	viability after 15 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.1477286643613711	[975]	[236,260]	-1	hSpCas9	negative selection	1305465
27433711	27433734	2	-	26627737	RPE1	viability after 15 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.46501703505142644	[894]	[159,205]	-3	hSpCas9	negative selection	1305466
27437291	27437314	2	+	26627737	RPE1	viability after 15 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-1.1829715906097167	[560]	[131,9]	-6	hSpCas9	negative selection	1305467
27439853	27439876	2	-	26627737	RPE1	viability after 15 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.6075467511909792	[1116]	[157,254]	-4	hSpCas9	negative selection	1305468
27440917	27440940	2	-	26627737	RPE1	viability after 15 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.15248651232469657	[896]	[420,147]	1	hSpCas9	negative selection	1305469
27441144	27441167	2	+	26627737	RPE1	viability after 15 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.2167598733347922	[820]	[292,109]	-1	hSpCas9	negative selection	1305470
27433263	27433286	2	+	26627737	RPE1	viability after 18 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.7235921634005391	[975]	[115,205]	-4	hSpCas9	negative selection	1387780
27433711	27433734	2	-	26627737	RPE1	viability after 18 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-1.3319680417493394	[894]	[35,159]	-7	hSpCas9	negative selection	1387781
27437291	27437314	2	+	26627737	RPE1	viability after 18 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-1.0962987988371584	[560]	[108,29]	-6	hSpCas9	negative selection	1387782
27439853	27439876	2	-	26627737	RPE1	viability after 18 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.9762585120763099	[1116]	[13,301]	-6	hSpCas9	negative selection	1387783
27440917	27440940	2	-	26627737	RPE1	viability after 18 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.3527548605317277	[896]	[205,171]	-2	hSpCas9	negative selection	1387784
27441144	27441167	2	+	26627737	RPE1	viability after 18 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.29440884158694314	[820]	[199,159]	-2	hSpCas9	negative selection	1387785
27433263	27433286	2	+	26627737	HeLa	viability after 8 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-1.3968848741356752	[985]	[174,146,168]	-8	hSpCas9	negative selection	1470095
27433711	27433734	2	-	26627737	HeLa	viability after 8 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	2.080970089638492	[83]	[99,168,180]	9	hSpCas9	negative selection	1470096
27437291	27437314	2	+	26627737	HeLa	viability after 8 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-0.8750702624449835	[348]	[23,195,19]	-7	hSpCas9	negative selection	1470097
27439853	27439876	2	-	26627737	HeLa	viability after 8 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.15663492261506792	[386]	[78,127,224]	-1	hSpCas9	negative selection	1470098
27440917	27440940	2	-	26627737	HeLa	viability after 8 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.38562046697004837	[529]	[389,418,126]	3	hSpCas9	negative selection	1470099
27441144	27441167	2	+	26627737	HeLa	viability after 8 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.6220334063172779	[347]	[196,52,68]	-6	hSpCas9	negative selection	1470100
27433263	27433286	2	+	26627737	HeLa	viability after 12 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-1.0189045345502419	[985]	[234,193,175]	-7	hSpCas9	negative selection	1552410
27433711	27433734	2	-	26627737	HeLa	viability after 12 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	2.137413049894202	[83]	[244,94,126]	9	hSpCas9	negative selection	1552411
27437291	27437314	2	+	26627737	HeLa	viability after 12 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-1.3069853506508113	[348]	[88,74,9]	-8	hSpCas9	negative selection	1552412
27439853	27439876	2	-	26627737	HeLa	viability after 12 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.17881553818160406	[386]	[79,160,178]	-1	hSpCas9	negative selection	1552413
27440917	27440940	2	-	26627737	HeLa	viability after 12 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.13382406554388648	[529]	[76,296,210]	-1	hSpCas9	negative selection	1552414
27441144	27441167	2	+	26627737	HeLa	viability after 12 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	0.09264365826761109	[347]	[173,102,188]	0	hSpCas9	negative selection	1552415
27433263	27433286	2	+	26627737	HeLa	viability after 15 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-2.0131469575745897	[985]	[41,97,163]	-9	hSpCas9	negative selection	1634725
27433711	27433734	2	-	26627737	HeLa	viability after 15 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	1.6507385845302847	[83]	[150,69,99]	9	hSpCas9	negative selection	1634726
27437291	27437314	2	+	26627737	HeLa	viability after 15 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-0.9138930585653962	[348]	[17,108,101]	-7	hSpCas9	negative selection	1634727
27439853	27439876	2	-	26627737	HeLa	viability after 15 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.2213336213575145	[386]	[188,28,190]	-2	hSpCas9	negative selection	1634728
27440917	27440940	2	-	26627737	HeLa	viability after 15 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.38429102855489894	[529]	[68,276,149]	-3	hSpCas9	negative selection	1634729
27441144	27441167	2	+	26627737	HeLa	viability after 15 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-1.075509227774653	[347]	[106,52,38]	-7	hSpCas9	negative selection	1634730
27433263	27433286	2	+	26627737	HeLa	viability after 18 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-2.0609017163330705	[985]	[25,75,163]	-9	hSpCas9	negative selection	1717040
27433711	27433734	2	-	26627737	HeLa	viability after 18 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	1.6815894639153646	[83]	[104,58,99]	9	hSpCas9	negative selection	1717041
27437291	27437314	2	+	26627737	HeLa	viability after 18 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-0.88546726061525	[348]	[11,93,101]	-7	hSpCas9	negative selection	1717042
27439853	27439876	2	-	26627737	HeLa	viability after 18 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.24916837649170995	[386]	[120,24,190]	-2	hSpCas9	negative selection	1717043
27440917	27440940	2	-	26627737	HeLa	viability after 18 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.36728499673173653	[529]	[47,231,149]	-3	hSpCas9	negative selection	1717044
27441144	27441167	2	+	26627737	HeLa	viability after 18 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-1.2650903241999865	[347]	[57,40,38]	-8	hSpCas9	negative selection	1717045
27433263	27433286	2	+	26627737	HCT116	viability after 6 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	0.5122370388591492	[673]	[76,191]	3	hSpCas9	negative selection	1799355
27433711	27433734	2	-	26627737	HCT116	viability after 6 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	0.9551809171754004	[377]	[33,159]	5	hSpCas9	negative selection	1799356
27437291	27437314	2	+	26627737	HCT116	viability after 6 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-0.42354186744184097	[398]	[107,12]	-2	hSpCas9	negative selection	1799357
27439853	27439876	2	-	26627737	HCT116	viability after 6 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	1.7716582927632025	[195]	[188,58]	8	hSpCas9	negative selection	1799358
27440917	27440940	2	-	26627737	HCT116	viability after 6 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.13718394979373869	[697]	[102,97]	0	hSpCas9	negative selection	1799359
27441144	27441167	2	+	26627737	HCT116	viability after 6 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	0.23980995935328508	[909]	[195,153]	1	hSpCas9	negative selection	1799360
27433263	27433286	2	+	26627737	HCT116	viability after 8 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.6132207654935673	[533]	[302,78,196]	-6	hSpCas9	negative selection	1881670
27433711	27433734	2	-	26627737	HCT116	viability after 8 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	0.14743747694816517	[224]	[190,90,130]	1	hSpCas9	negative selection	1881671
27437291	27437314	2	+	26627737	HCT116	viability after 8 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	2.412205640324512	[16]	[66,41,40]	9	hSpCas9	negative selection	1881672
27439853	27439876	2	-	26627737	HCT116	viability after 8 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-3.4649001580943706	[452]	[32,11,22]	-9	hSpCas9	negative selection	1881673
27440917	27440940	2	-	26627737	HCT116	viability after 8 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.4401574594858183	[337]	[178,131,101]	-5	hSpCas9	negative selection	1881674
27441144	27441167	2	+	26627737	HCT116	viability after 8 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.19320434576166007	[406]	[242,206,139]	-2	hSpCas9	negative selection	1881675
27433263	27433286	2	+	26627737	HCT116	viability after 9 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-1.3429666280164922	[673]	[142,13]	-7	hSpCas9	negative selection	1963985
27433711	27433734	2	-	26627737	HCT116	viability after 9 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	0.8349614730900994	[377]	[336,55]	6	hSpCas9	negative selection	1963986
27437291	27437314	2	+	26627737	HCT116	viability after 9 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-2.5602844698767004	[398]	[26,10]	-9	hSpCas9	negative selection	1963987
27439853	27439876	2	-	26627737	HCT116	viability after 9 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-1.4734687628649044	[195]	[5,28]	-8	hSpCas9	negative selection	1963988
27440917	27440940	2	-	26627737	HCT116	viability after 9 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.0278858360751503	[697]	[155,203]	0	hSpCas9	negative selection	1963989
27441144	27441167	2	+	26627737	HCT116	viability after 9 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.37519972554897774	[909]	[102,253]	-3	hSpCas9	negative selection	1963990
27433263	27433286	2	+	26627737	HCT116	viability after 12 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.9521148651827493	[533]	[180,103,145]	-8	hSpCas9	negative selection	2046300
27433711	27433734	2	-	26627737	HCT116	viability after 12 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.401760350529791	[224]	[88,107,71]	-4	hSpCas9	negative selection	2046301
27437291	27437314	2	+	26627737	HCT116	viability after 12 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	2.556550760076971	[16]	[88,32,31]	9	hSpCas9	negative selection	2046302
27439853	27439876	2	-	26627737	HCT116	viability after 12 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-3.3245264882756045	[452]	[30,37,1]	-9	hSpCas9	negative selection	2046303
27440917	27440940	2	-	26627737	HCT116	viability after 12 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.4251778083979777	[337]	[289,320,101]	4	hSpCas9	negative selection	2046304
27441144	27441167	2	+	26627737	HCT116	viability after 12 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.25871978251397576	[406]	[223,122,183]	-3	hSpCas9	negative selection	2046305
27433263	27433286	2	+	26627737	HCT116	viability after 15 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.9381924801408056	[533]	[184,122,174]	-7	hSpCas9	negative selection	2128615
27433711	27433734	2	-	26627737	HCT116	viability after 15 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.39361241911694966	[224]	[137,70,90]	-4	hSpCas9	negative selection	2128616
27437291	27437314	2	+	26627737	HCT116	viability after 15 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	2.8485412567587423	[16]	[64,48,95]	9	hSpCas9	negative selection	2128617
27439853	27439876	2	-	26627737	HCT116	viability after 15 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-3.8467451253036016	[452]	[38,16,0]	-9	hSpCas9	negative selection	2128618
27440917	27440940	2	-	26627737	HCT116	viability after 15 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.006162205303858415	[337]	[117,306,150]	0	hSpCas9	negative selection	2128619
27441144	27441167	2	+	26627737	HCT116	viability after 15 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.4560000449262943	[406]	[163,224,121]	-5	hSpCas9	negative selection	2128620
27433263	27433286	2	+	26627737	HCT116	viability after 18 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.8322047593932398	[533]	[141,171,117]	-6	hSpCas9	negative selection	2210930
27433711	27433734	2	-	26627737	HCT116	viability after 18 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-1.6895831258459246	[224]	[22,30,47]	-8	hSpCas9	negative selection	2210931
27437291	27437314	2	+	26627737	HCT116	viability after 18 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	0.7656221215076973	[16]	[15,20,3]	6	hSpCas9	negative selection	2210932
27439853	27439876	2	-	26627737	HCT116	viability after 18 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-4.0470272919568835	[452]	[10,11,16]	-9	hSpCas9	negative selection	2210933
27440917	27440940	2	-	26627737	HCT116	viability after 18 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.11123469461573099	[337]	[157,256,105]	1	hSpCas9	negative selection	2210934
27441144	27441167	2	+	26627737	HCT116	viability after 18 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.6397515843500976	[406]	[222,93,60]	-5	hSpCas9	negative selection	2210935
27433261	27433284	2	+	24336569	HL60	viability	TGTTCCTTCCAGCATGTCGGAGG	NRBP1	ENSG00000115216	-0.34554812094397425	[274]	[457]	-3	hSpCas9	negative selection	2281271
27433289	27433312	2	+	24336569	HL60	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	0.30361337816538136	[370]	[968]	3	hSpCas9	negative selection	2281272
27433303	27433326	2	+	24336569	HL60	viability	TAGCAGTGGCTCAGACCCAAAGG	NRBP1	ENSG00000115216	-1.1660763283438373	[315]	[297]	-8	hSpCas9	negative selection	2281273
27433318	27433341	2	-	24336569	HL60	viability	AAGATGAGGATTCTACCTTTGGG	NRBP1	ENSG00000115216	0.07395365722891789	[1054]	[2349]	0	hSpCas9	negative selection	2281274
27433328	27433351	2	+	24336569	HL60	viability	GAATCCTCATCTTCAGCTCCTGG	NRBP1	ENSG00000115216	0.16595598738913264	[448]	[1065]	1	hSpCas9	negative selection	2281275
27433346	27433369	2	-	24336569	HL60	viability	GGTGACACTGATGTCAGGCCAGG	NRBP1	ENSG00000115216	-2.0341583858505397	[179]	[92]	-9	hSpCas9	negative selection	2281276
27433351	27433374	2	-	24336569	HL60	viability	CAGGAGGTGACACTGATGTCAGG	NRBP1	ENSG00000115216	1.5149031633645094	[356]	[2158]	8	hSpCas9	negative selection	2281277
27433367	27433390	2	-	24336569	HL60	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-0.7752564638633007	[811]	[1003]	-6	hSpCas9	negative selection	2281278
27433377	27433400	2	-	24336569	HL60	viability	GGAAGCAGCTGAGGTTGTGGAGG	NRBP1	ENSG00000115216	0.37521508169258855	[1096]	[3010]	3	hSpCas9	negative selection	2281279
27433399	27433422	2	-	24336569	HL60	viability	CACTTTCTTCTTCTTCCTCTGGG	NRBP1	ENSG00000115216	6.377967518008401	[0]	[175]	9	hSpCas9	negative selection	2281280
27433261	27433284	2	+	24336569	KBM7	viability	TGTTCCTTCCAGCATGTCGGAGG	NRBP1	ENSG00000115216	-1.0381444034994147	[386]	[513]	-6	hSpCas9	negative selection	2348448
27433289	27433312	2	+	24336569	KBM7	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.0662038646315738	[270]	[705]	0	hSpCas9	negative selection	2348449
27433303	27433326	2	+	24336569	KBM7	viability	TAGCAGTGGCTCAGACCCAAAGG	NRBP1	ENSG00000115216	-2.182751508892038	[535]	[321]	-8	hSpCas9	negative selection	2348450
27433318	27433341	2	-	24336569	KBM7	viability	AAGATGAGGATTCTACCTTTGGG	NRBP1	ENSG00000115216	0.5416140484945345	[535]	[2127]	5	hSpCas9	negative selection	2348451
27433328	27433351	2	+	24336569	KBM7	viability	GAATCCTCATCTTCAGCTCCTGG	NRBP1	ENSG00000115216	-0.7446754384563092	[179]	[292]	-5	hSpCas9	negative selection	2348452
27433346	27433369	2	-	24336569	KBM7	viability	GGTGACACTGATGTCAGGCCAGG	NRBP1	ENSG00000115216	-6.805131201166965	[40]	[0]	-9	hSpCas9	negative selection	2348453
27433351	27433374	2	-	24336569	KBM7	viability	CAGGAGGTGACACTGATGTCAGG	NRBP1	ENSG00000115216	-0.1149757196680492	[753]	[1898]	-1	hSpCas9	negative selection	2348454
27433367	27433390	2	-	24336569	KBM7	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-2.821459371070967	[621]	[239]	-9	hSpCas9	negative selection	2348455
27433377	27433400	2	-	24336569	KBM7	viability	GGAAGCAGCTGAGGTTGTGGAGG	NRBP1	ENSG00000115216	-0.46574939946340077	[798]	[1577]	-4	hSpCas9	negative selection	2348456
27433399	27433422	2	-	24336569	KBM7	viability	CACTTTCTTCTTCTTCCTCTGGG	NRBP1	ENSG00000115216	0.5605947348968177	[87]	[353]	5	hSpCas9	negative selection	2348457
27442198	27442221	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGAATCGAATGGCCCCCCAGG	NRBP1	ENSG00000115216	-0.4081138753628346	[24,386]	[17,51]	-2	dCas9-VP64	positive selection	2405731
27442219	27442242	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTTATTACAGCAGCAACTGAGG	NRBP1	ENSG00000115216	-1.72125778652287	[160,194]	[13,8]	-8	dCas9-VP64	positive selection	2405732
27428512	27428535	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCGGCCCTCGGGCGTTCGCTGG	NRBP1	ENSG00000115216	0.7439632304996453	[309,38]	[119,1]	3	dCas9-VP64	positive selection	2442915
27428454	27428477	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTCCGGCCGAGACCTCTCGGAGG	NRBP1	ENSG00000115216	1.2664634857093533	[36,22]	[23,6]	5	dCas9-VP64	positive selection	2442916
27428429	27428452	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCGATGTTTTCGGTCCCAGCTGG	NRBP1	ENSG00000115216	4.110961101055071	[420,34]	[1574,85]	9	dCas9-VP64	positive selection	2442917
27429040	27429063	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGGCGGGGGCGGGGGCGGCGG	NRBP1	ENSG00000115216	2.532533376556697	[0,1]	[0,2]	8	dCas9-VP64	positive selection	2465352
27442198	27442221	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGAATCGAATGGCCCCCCAGG	NRBP1	ENSG00000115216	0.10126332419557971	[44,68]	[16,21]	0	dCas9-VP64	positive selection	2500986
27442219	27442242	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTTATTACAGCAGCAACTGAGG	NRBP1	ENSG00000115216	3.573844658385963	[149,224]	[1273,218]	9	dCas9-VP64	positive selection	2500987
27428512	27428535	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCGGCCCTCGGGCGTTCGCTGG	NRBP1	ENSG00000115216	-0.5054135113937879	[157,169]	[52,21]	-5	dCas9-VP64	positive selection	2538170
27428454	27428477	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTCCGGCCGAGACCTCTCGGAGG	NRBP1	ENSG00000115216	0.03595959967222384	[53,58]	[17,18]	0	dCas9-VP64	positive selection	2538171
27428429	27428452	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCGATGTTTTCGGTCCCAGCTGG	NRBP1	ENSG00000115216	-0.3684344451622029	[231,243]	[49,68]	-4	dCas9-VP64	positive selection	2538172
27429040	27429063	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGGCGGGGGCGGGGGCGGCGG	NRBP1	ENSG00000115216	0.4348111379075954	[3,1]	[0,0]	3	dCas9-VP64	positive selection	2560607
27433346	27433369	2	-	27260157	DLD1	viability	GGTGACACTGATGTCAGGCCAGG	NRBP1	ENSG00000115216	-0.769801667902629	[]	[]	-5	hSpCas9	negative selection	2575289
27433290	27433313	2	-	27260157	DLD1	viability	GCCACTGCTAAGTACTGTCTGGG	NRBP1	ENSG00000115216	-2.11233395120336	[]	[]	-8	hSpCas9	negative selection	2576039
27433377	27433400	2	-	27260157	DLD1	viability	GGAAGCAGCTGAGGTTGTGGAGG	NRBP1	ENSG00000115216	-1.31094754223183	[]	[]	-7	hSpCas9	negative selection	2577401
27433443	27433466	2	+	27260157	DLD1	viability	AAGAGTCGCCCTGTGGGCGCTGG	NRBP1	ENSG00000115216	-0.348004386937896	[]	[]	-3	hSpCas9	negative selection	2582163
27433261	27433284	2	+	27260157	DLD1	viability	TGTTCCTTCCAGCATGTCGGAGG	NRBP1	ENSG00000115216	-2.04518475400429	[]	[]	-8	hSpCas9	negative selection	2583267
27433771	27433794	2	+	27260157	DLD1	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	0.284175643545293	[]	[]	4	hSpCas9	negative selection	2584947
27433351	27433374	2	-	27260157	DLD1	viability	CAGGAGGTGACACTGATGTCAGG	NRBP1	ENSG00000115216	-0.800899002043755	[]	[]	-6	hSpCas9	negative selection	2604409
27433399	27433422	2	-	27260157	DLD1	viability	CACTTTCTTCTTCTTCCTCTGGG	NRBP1	ENSG00000115216	0.257607779793517	[]	[]	4	hSpCas9	negative selection	2609724
27433691	27433714	2	-	27260157	DLD1	viability	AGGTATGCACTGTCAATACCTGG	NRBP1	ENSG00000115216	-0.8303768507089	[]	[]	-6	hSpCas9	negative selection	2609842
27433720	27433743	2	+	27260157	DLD1	viability	GGATACAGAGGAAGGTGTAGAGG	NRBP1	ENSG00000115216	-2.02483000509953	[]	[]	-8	hSpCas9	negative selection	2613330
27433289	27433312	2	+	27260157	DLD1	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-1.5422935789568	[]	[]	-8	hSpCas9	negative selection	2615231
27433673	27433696	2	+	27260157	DLD1	viability	GTGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-1.35947233179588	[]	[]	-8	hSpCas9	negative selection	2616387
27433711	27433734	2	-	27260157	DLD1	viability	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	0.215816580164217	[]	[]	3	hSpCas9	negative selection	2616640
27433735	27433758	2	+	27260157	DLD1	viability	TGTAGAGGTTGTGTGGAATGAGG	NRBP1	ENSG00000115216	-3.0245950596693	[]	[]	-9	hSpCas9	negative selection	2616928
27433258	27433281	2	+	27260157	DLD1	viability	GAGTGTTCCTTCCAGCATGTCGG	NRBP1	ENSG00000115216	-2.262130216029	[]	[]	-9	hSpCas9	negative selection	2617744
27433328	27433351	2	+	27260157	DLD1	viability	GAATCCTCATCTTCAGCTCCTGG	NRBP1	ENSG00000115216	-0.742712430861533	[]	[]	-5	hSpCas9	negative selection	2618486
27433693	27433716	2	+	27260157	DLD1	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-2.97213394880255	[]	[]	-9	hSpCas9	negative selection	2619886
27433367	27433390	2	-	27260157	DLD1	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-2.75478648748642	[]	[]	-9	hSpCas9	negative selection	2621338
27433318	27433341	2	-	27260157	DLD1	viability	AAGATGAGGATTCTACCTTTGGG	NRBP1	ENSG00000115216	-0.894017475079823	[]	[]	-6	hSpCas9	negative selection	2640776
27433303	27433326	2	+	27260157	DLD1	viability	TAGCAGTGGCTCAGACCCAAAGG	NRBP1	ENSG00000115216	-1.72103872122528	[]	[]	-8	hSpCas9	negative selection	2644965
27433346	27433369	2	-	27260157	HT1080	viability	GGTGACACTGATGTCAGGCCAGG	NRBP1	ENSG00000115216	-0.178885246721285	[]	[]	0	hSpCas9	negative selection	2651419
27433290	27433313	2	-	27260157	HT1080	viability	GCCACTGCTAAGTACTGTCTGGG	NRBP1	ENSG00000115216	-2.11804380214143	[]	[]	-9	hSpCas9	negative selection	2652169
27433377	27433400	2	-	27260157	HT1080	viability	GGAAGCAGCTGAGGTTGTGGAGG	NRBP1	ENSG00000115216	0.0736548876933475	[]	[]	0	hSpCas9	negative selection	2653531
27433443	27433466	2	+	27260157	HT1080	viability	AAGAGTCGCCCTGTGGGCGCTGG	NRBP1	ENSG00000115216	0.818144264637907	[]	[]	7	hSpCas9	negative selection	2658293
27433261	27433284	2	+	27260157	HT1080	viability	TGTTCCTTCCAGCATGTCGGAGG	NRBP1	ENSG00000115216	-1.85884091227979	[]	[]	-9	hSpCas9	negative selection	2659397
27433771	27433794	2	+	27260157	HT1080	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.533441451326539	[]	[]	-7	hSpCas9	negative selection	2661077
27433351	27433374	2	-	27260157	HT1080	viability	CAGGAGGTGACACTGATGTCAGG	NRBP1	ENSG00000115216	-1.2134394126007	[]	[]	-8	hSpCas9	negative selection	2680539
27433399	27433422	2	-	27260157	HT1080	viability	CACTTTCTTCTTCTTCCTCTGGG	NRBP1	ENSG00000115216	0.889416638699408	[]	[]	7	hSpCas9	negative selection	2685854
27433691	27433714	2	-	27260157	HT1080	viability	AGGTATGCACTGTCAATACCTGG	NRBP1	ENSG00000115216	-0.390038344058191	[]	[]	-7	hSpCas9	negative selection	2685972
27433720	27433743	2	+	27260157	HT1080	viability	GGATACAGAGGAAGGTGTAGAGG	NRBP1	ENSG00000115216	-3.36013773794948	[]	[]	-9	hSpCas9	negative selection	2689460
27433289	27433312	2	+	27260157	HT1080	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.726169121781854	[]	[]	-8	hSpCas9	negative selection	2691361
27433673	27433696	2	+	27260157	HT1080	viability	GTGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-1.63056111941237	[]	[]	-9	hSpCas9	negative selection	2692517
27433711	27433734	2	-	27260157	HT1080	viability	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.617443291497749	[]	[]	-8	hSpCas9	negative selection	2692770
27433735	27433758	2	+	27260157	HT1080	viability	TGTAGAGGTTGTGTGGAATGAGG	NRBP1	ENSG00000115216	-2.35383971487881	[]	[]	-9	hSpCas9	negative selection	2693058
27433258	27433281	2	+	27260157	HT1080	viability	GAGTGTTCCTTCCAGCATGTCGG	NRBP1	ENSG00000115216	-3.51684015268911	[]	[]	-9	hSpCas9	negative selection	2693874
27433328	27433351	2	+	27260157	HT1080	viability	GAATCCTCATCTTCAGCTCCTGG	NRBP1	ENSG00000115216	0.600861864417346	[]	[]	5	hSpCas9	negative selection	2694616
27433693	27433716	2	+	27260157	HT1080	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.97851198137167	[]	[]	-9	hSpCas9	negative selection	2696016
27433367	27433390	2	-	27260157	HT1080	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-2.24907814141368	[]	[]	-9	hSpCas9	negative selection	2697468
27433318	27433341	2	-	27260157	HT1080	viability	AAGATGAGGATTCTACCTTTGGG	NRBP1	ENSG00000115216	-1.95492103720376	[]	[]	-9	hSpCas9	negative selection	2716906
27433303	27433326	2	+	27260157	HT1080	viability	TAGCAGTGGCTCAGACCCAAAGG	NRBP1	ENSG00000115216	-1.43396552674137	[]	[]	-9	hSpCas9	negative selection	2721095
27433346	27433369	2	-	27260157	MKN45	viability	GGTGACACTGATGTCAGGCCAGG	NRBP1	ENSG00000115216	-0.111551730050225	[]	[]	0	hSpCas9	negative selection	2727549
27433290	27433313	2	-	27260157	MKN45	viability	GCCACTGCTAAGTACTGTCTGGG	NRBP1	ENSG00000115216	-0.296377664545342	[]	[]	-1	hSpCas9	negative selection	2728299
27433377	27433400	2	-	27260157	MKN45	viability	GGAAGCAGCTGAGGTTGTGGAGG	NRBP1	ENSG00000115216	-1.49863112871344	[]	[]	-8	hSpCas9	negative selection	2729661
27433443	27433466	2	+	27260157	MKN45	viability	AAGAGTCGCCCTGTGGGCGCTGG	NRBP1	ENSG00000115216	-0.685978863884172	[]	[]	-7	hSpCas9	negative selection	2734423
27433261	27433284	2	+	27260157	MKN45	viability	TGTTCCTTCCAGCATGTCGGAGG	NRBP1	ENSG00000115216	-2.37557376625382	[]	[]	-9	hSpCas9	negative selection	2735527
27433771	27433794	2	+	27260157	MKN45	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	0.693496831035775	[]	[]	7	hSpCas9	negative selection	2737207
27433351	27433374	2	-	27260157	MKN45	viability	CAGGAGGTGACACTGATGTCAGG	NRBP1	ENSG00000115216	-0.444307915927845	[]	[]	-6	hSpCas9	negative selection	2756669
27433399	27433422	2	-	27260157	MKN45	viability	CACTTTCTTCTTCTTCCTCTGGG	NRBP1	ENSG00000115216	0.403065708284334	[]	[]	6	hSpCas9	negative selection	2761984
27433691	27433714	2	-	27260157	MKN45	viability	AGGTATGCACTGTCAATACCTGG	NRBP1	ENSG00000115216	-1.34347696745737	[]	[]	-8	hSpCas9	negative selection	2762102
27433720	27433743	2	+	27260157	MKN45	viability	GGATACAGAGGAAGGTGTAGAGG	NRBP1	ENSG00000115216	-1.72698503459634	[]	[]	-9	hSpCas9	negative selection	2765590
27433289	27433312	2	+	27260157	MKN45	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.346635250600889	[]	[]	-1	hSpCas9	negative selection	2767491
27433673	27433696	2	+	27260157	MKN45	viability	GTGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-0.438508173182519	[]	[]	-6	hSpCas9	negative selection	2768647
27433711	27433734	2	-	27260157	MKN45	viability	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.181985320642892	[]	[]	0	hSpCas9	negative selection	2768900
27433735	27433758	2	+	27260157	MKN45	viability	TGTAGAGGTTGTGTGGAATGAGG	NRBP1	ENSG00000115216	-2.5419780933277	[]	[]	-9	hSpCas9	negative selection	2769188
27433258	27433281	2	+	27260157	MKN45	viability	GAGTGTTCCTTCCAGCATGTCGG	NRBP1	ENSG00000115216	-1.40334372888308	[]	[]	-8	hSpCas9	negative selection	2770004
27433328	27433351	2	+	27260157	MKN45	viability	GAATCCTCATCTTCAGCTCCTGG	NRBP1	ENSG00000115216	0.697487578420178	[]	[]	7	hSpCas9	negative selection	2770746
27433693	27433716	2	+	27260157	MKN45	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-2.06010026306012	[]	[]	-9	hSpCas9	negative selection	2772146
27433367	27433390	2	-	27260157	MKN45	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-1.57205247587833	[]	[]	-9	hSpCas9	negative selection	2773598
27433318	27433341	2	-	27260157	MKN45	viability	AAGATGAGGATTCTACCTTTGGG	NRBP1	ENSG00000115216	0.933739841274825	[]	[]	8	hSpCas9	negative selection	2793036
27433303	27433326	2	+	27260157	MKN45	viability	TAGCAGTGGCTCAGACCCAAAGG	NRBP1	ENSG00000115216	-1.89844104997681	[]	[]	-9	hSpCas9	negative selection	2797225
27433346	27433369	2	-	27260157	RKO	viability	GGTGACACTGATGTCAGGCCAGG	NRBP1	ENSG00000115216	-0.955051520320212	[]	[]	-8	hSpCas9	negative selection	2803679
27433290	27433313	2	-	27260157	RKO	viability	GCCACTGCTAAGTACTGTCTGGG	NRBP1	ENSG00000115216	-1.41089107054479	[]	[]	-8	hSpCas9	negative selection	2804429
27433377	27433400	2	-	27260157	RKO	viability	GGAAGCAGCTGAGGTTGTGGAGG	NRBP1	ENSG00000115216	-2.13429747555013	[]	[]	-9	hSpCas9	negative selection	2805791
27433443	27433466	2	+	27260157	RKO	viability	AAGAGTCGCCCTGTGGGCGCTGG	NRBP1	ENSG00000115216	1.33249554275796	[]	[]	9	hSpCas9	negative selection	2810553
27433261	27433284	2	+	27260157	RKO	viability	TGTTCCTTCCAGCATGTCGGAGG	NRBP1	ENSG00000115216	-2.04014171249475	[]	[]	-9	hSpCas9	negative selection	2811657
27433771	27433794	2	+	27260157	RKO	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	0.134278251575007	[]	[]	0	hSpCas9	negative selection	2813337
27433351	27433374	2	-	27260157	RKO	viability	CAGGAGGTGACACTGATGTCAGG	NRBP1	ENSG00000115216	-1.9803636070413	[]	[]	-9	hSpCas9	negative selection	2832799
27433399	27433422	2	-	27260157	RKO	viability	CACTTTCTTCTTCTTCCTCTGGG	NRBP1	ENSG00000115216	0.53644399489825	[]	[]	3	hSpCas9	negative selection	2838114
27433691	27433714	2	-	27260157	RKO	viability	AGGTATGCACTGTCAATACCTGG	NRBP1	ENSG00000115216	-1.14672276725872	[]	[]	-8	hSpCas9	negative selection	2838232
27433720	27433743	2	+	27260157	RKO	viability	GGATACAGAGGAAGGTGTAGAGG	NRBP1	ENSG00000115216	-1.67423997013424	[]	[]	-9	hSpCas9	negative selection	2841720
27433289	27433312	2	+	27260157	RKO	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-1.27929065793554	[]	[]	-8	hSpCas9	negative selection	2843621
27433673	27433696	2	+	27260157	RKO	viability	GTGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-0.9045829663345	[]	[]	-8	hSpCas9	negative selection	2844777
27433711	27433734	2	-	27260157	RKO	viability	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.341075618006212	[]	[]	-6	hSpCas9	negative selection	2845030
27433735	27433758	2	+	27260157	RKO	viability	TGTAGAGGTTGTGTGGAATGAGG	NRBP1	ENSG00000115216	-2.65090838810574	[]	[]	-9	hSpCas9	negative selection	2845318
27433258	27433281	2	+	27260157	RKO	viability	GAGTGTTCCTTCCAGCATGTCGG	NRBP1	ENSG00000115216	-3.13856286423702	[]	[]	-9	hSpCas9	negative selection	2846134
27433328	27433351	2	+	27260157	RKO	viability	GAATCCTCATCTTCAGCTCCTGG	NRBP1	ENSG00000115216	-0.311962234368128	[]	[]	-6	hSpCas9	negative selection	2846876
27433693	27433716	2	+	27260157	RKO	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-2.65785926775995	[]	[]	-9	hSpCas9	negative selection	2848276
27433367	27433390	2	-	27260157	RKO	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-3.57053929486143	[]	[]	-9	hSpCas9	negative selection	2849728
27433318	27433341	2	-	27260157	RKO	viability	AAGATGAGGATTCTACCTTTGGG	NRBP1	ENSG00000115216	-0.201115616787287	[]	[]	-1	hSpCas9	negative selection	2869166
27433303	27433326	2	+	27260157	RKO	viability	TAGCAGTGGCTCAGACCCAAAGG	NRBP1	ENSG00000115216	-2.01806186904839	[]	[]	-9	hSpCas9	negative selection	2873355
27433346	27433369	2	-	27260157	SF268	viability	GGTGACACTGATGTCAGGCCAGG	NRBP1	ENSG00000115216	-0.733675693185892	[]	[]	-5	hSpCas9	negative selection	2879809
27433290	27433313	2	-	27260157	SF268	viability	GCCACTGCTAAGTACTGTCTGGG	NRBP1	ENSG00000115216	-0.397148187780769	[]	[]	-3	hSpCas9	negative selection	2880559
27433377	27433400	2	-	27260157	SF268	viability	GGAAGCAGCTGAGGTTGTGGAGG	NRBP1	ENSG00000115216	-0.556511334220087	[]	[]	-4	hSpCas9	negative selection	2881921
27433443	27433466	2	+	27260157	SF268	viability	AAGAGTCGCCCTGTGGGCGCTGG	NRBP1	ENSG00000115216	-0.38576742511149	[]	[]	-3	hSpCas9	negative selection	2886683
27433261	27433284	2	+	27260157	SF268	viability	TGTTCCTTCCAGCATGTCGGAGG	NRBP1	ENSG00000115216	-2.08084979615126	[]	[]	-9	hSpCas9	negative selection	2887787
27433771	27433794	2	+	27260157	SF268	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	0.122499987562376	[]	[]	0	hSpCas9	negative selection	2889467
27433351	27433374	2	-	27260157	SF268	viability	CAGGAGGTGACACTGATGTCAGG	NRBP1	ENSG00000115216	-0.00134092838767823	[]	[]	0	hSpCas9	negative selection	2908929
27433399	27433422	2	-	27260157	SF268	viability	CACTTTCTTCTTCTTCCTCTGGG	NRBP1	ENSG00000115216	0.319301126476765	[]	[]	4	hSpCas9	negative selection	2914244
27433691	27433714	2	-	27260157	SF268	viability	AGGTATGCACTGTCAATACCTGG	NRBP1	ENSG00000115216	-1.00402207274272	[]	[]	-7	hSpCas9	negative selection	2914362
27433720	27433743	2	+	27260157	SF268	viability	GGATACAGAGGAAGGTGTAGAGG	NRBP1	ENSG00000115216	-1.20177036670201	[]	[]	-7	hSpCas9	negative selection	2917850
27433289	27433312	2	+	27260157	SF268	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.390611110265712	[]	[]	-3	hSpCas9	negative selection	2919751
27433673	27433696	2	+	27260157	SF268	viability	GTGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-0.396540625330328	[]	[]	-3	hSpCas9	negative selection	2920907
27433711	27433734	2	-	27260157	SF268	viability	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	0.941306216287156	[]	[]	9	hSpCas9	negative selection	2921160
27433735	27433758	2	+	27260157	SF268	viability	TGTAGAGGTTGTGTGGAATGAGG	NRBP1	ENSG00000115216	-1.52584992687668	[]	[]	-8	hSpCas9	negative selection	2921448
27433258	27433281	2	+	27260157	SF268	viability	GAGTGTTCCTTCCAGCATGTCGG	NRBP1	ENSG00000115216	-1.63883514376076	[]	[]	-8	hSpCas9	negative selection	2922264
27433328	27433351	2	+	27260157	SF268	viability	GAATCCTCATCTTCAGCTCCTGG	NRBP1	ENSG00000115216	0.435856788204424	[]	[]	7	hSpCas9	negative selection	2923006
27433693	27433716	2	+	27260157	SF268	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.46008859074667	[]	[]	-8	hSpCas9	negative selection	2924406
27433367	27433390	2	-	27260157	SF268	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-1.90662825423251	[]	[]	-8	hSpCas9	negative selection	2925858
27433318	27433341	2	-	27260157	SF268	viability	AAGATGAGGATTCTACCTTTGGG	NRBP1	ENSG00000115216	0.415993006916681	[]	[]	4	hSpCas9	negative selection	2945296
27433303	27433326	2	+	27260157	SF268	viability	TAGCAGTGGCTCAGACCCAAAGG	NRBP1	ENSG00000115216	-0.954699126074457	[]	[]	-6	hSpCas9	negative selection	2949485
27433709	27433732	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-0.25615682824072294	[0,0]	[0,0]	-4	hSpCas9	positive selection	3006499
27434070	27434093	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	0.052249052417538716	[3,2]	[1,4]	1	hSpCas9	positive selection	3006500
27433709	27433732	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	0.4833744715089985	[0,0]	[0,0]	8	hSpCas9	positive selection	3074357
27434070	27434093	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-0.6890619484723772	[3,3]	[1,0]	-8	hSpCas9	positive selection	3074358
27434006	27434029		+	24336571	A375	resistance to PLX after 7 days	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	-0.12920464041349705	[11,11]	[10,10]	-4	hSpCas9	positive selection	3131573
27433716	27433739		-	24336571	A375	resistance to PLX after 7 days	TACACCTTCCTCTGTATCCATGG	NRBP1	ENSG00000115216	0.4572289366382504	[8,8]	[11,12]	9	hSpCas9	positive selection	3131574
27434041	27434064		+	24336571	A375	resistance to PLX after 7 days	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	-0.4729707308675478	[5,6]	[4,3]	-9	hSpCas9	positive selection	3131576
27434006	27434029		+	24336571	A375	resistance to PLX after 14 days	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.28933440818241374	[10,13]	[6,5]	3	hSpCas9	positive selection	3189366
27433716	27433739		-	24336571	A375	resistance to PLX after 14 days	TACACCTTCCTCTGTATCCATGG	NRBP1	ENSG00000115216	0.9098275363968011	[6,6]	[4,6]	7	hSpCas9	positive selection	3189367
27434041	27434064		+	24336571	A375	resistance to PLX after 14 days	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	-0.6243115786336244	[8,8]	[1,2]	-7	hSpCas9	positive selection	3189369
27434006	27434029		+	24336571	A375	viability after 7 days	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	-0.2539434949265521	[14]	[11,11]	-4	hSpCas9	negative selection	3247159
27433716	27433739		-	24336571	A375	viability after 7 days	TACACCTTCCTCTGTATCCATGG	NRBP1	ENSG00000115216	-2.0363047800046146	[39]	[8,8]	-9	hSpCas9	negative selection	3247160
27434041	27434064		+	24336571	A375	viability after 7 days	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	-0.5790738791648452	[9]	[5,6]	-7	hSpCas9	negative selection	3247162
27434006	27434029		+	24336571	A375	viability after 14 days	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	-0.23013811889960817	[14]	[10,13]	-3	hSpCas9	negative selection	3304952
27433716	27433739		-	24336571	A375	viability after 14 days	TACACCTTCCTCTGTATCCATGG	NRBP1	ENSG00000115216	-2.323041914455697	[39]	[6,6]	-9	hSpCas9	negative selection	3304953
27434041	27434064		+	24336571	A375	viability after 14 days	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	-0.1037477906784694	[9]	[8,8]	-1	hSpCas9	negative selection	3304955
27434748	27434771	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	1.0093986980022496	[75,75]	[0,0]	4	hSpCas9	positive selection	3382370
27434006	27434029	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	-1.5723965236402235	[454,454]	[0,0]	-9	hSpCas9	positive selection	3382371
27434041	27434064	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	-1.4908666381436253	[429,429]	[0,0]	-8	hSpCas9	positive selection	3382372
27435185	27435208	2	+	26780180	HT29	viability (Avana library 4 designs)	ACCATCTTCATCCAGCACAACGG	NRBP1	ENSG00000115216	4.54101372664636	[]	[]	9	hSpCas9	negative selection	3444388
27433708	27433731	2	+	26780180	HT29	viability (Avana library 4 designs)	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	2.59023046291443	[]	[]	8	hSpCas9	negative selection	3444389
27434069	27434092	2	+	26780180	HT29	viability (Avana library 4 designs)	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	3.50929244947551	[]	[]	9	hSpCas9	negative selection	3444390
27433720	27433743	2	+	26780180	HT29	viability (Avana library 4 designs)	GGATACAGAGGAAGGTGTAGAGG	NRBP1	ENSG00000115216	4.19088411848097	[]	[]	9	hSpCas9	negative selection	3444391
27435185	27435208	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCATCTTCATCCAGCACAACGG	NRBP1	ENSG00000115216	-20.4507348565456	[]	[]	-9	hSpCas9	negative selection	3536597
27433720	27433743	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATACAGAGGAAGGTGTAGAGG	NRBP1	ENSG00000115216	-13.667540236965	[]	[]	-8	hSpCas9	negative selection	3536598
27434069	27434092	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-4.71914251129758	[]	[]	-5	hSpCas9	negative selection	3536599
27433708	27433731	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-7.1969274242705	[]	[]	-6	hSpCas9	negative selection	3536600
27435185	27435208	2	+	26780180	A375	viability (Avana lentiGuide)	ACCATCTTCATCCAGCACAACGG	NRBP1	ENSG00000115216	10.6937675883391	[]	[]	7	hSpCas9	negative selection	3645256
27433720	27433743	2	+	26780180	A375	viability (Avana lentiGuide)	GGATACAGAGGAAGGTGTAGAGG	NRBP1	ENSG00000115216	8.41188116062613	[]	[]	6	hSpCas9	negative selection	3645257
27434069	27434092	2	+	26780180	A375	viability (Avana lentiGuide)	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	6.37518302749691	[]	[]	5	hSpCas9	negative selection	3645258
27433708	27433731	2	+	26780180	A375	viability (Avana lentiGuide)	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	18.7817090292622	[]	[]	8	hSpCas9	negative selection	3645259
27435185	27435208	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCATCTTCATCCAGCACAACGG	NRBP1	ENSG00000115216	-1.3005139916241402	[6]	[2,1]	-9	hSpCas9	positive selection	3753915
27433720	27433743	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATACAGAGGAAGGTGTAGAGG	NRBP1	ENSG00000115216	-0.842937332749201	[5]	[3,1]	-8	hSpCas9	positive selection	3753916
27434069	27434092	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-0.5415756070123566	[5]	[3,3]	-7	hSpCas9	positive selection	3753917
27433708	27433731	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-0.8991497881184013	[4]	[2,0]	-8	hSpCas9	positive selection	3753918
27435185	27435208	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCATCTTCATCCAGCACAACGG	NRBP1	ENSG00000115216	-0.2612312818104673	[6]	[4,3]	-4	hSpCas9	positive selection	3862522
27433720	27433743	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATACAGAGGAAGGTGTAGAGG	NRBP1	ENSG00000115216	-1.0413726848863216	[4]	[1,0]	-8	hSpCas9	positive selection	3862523
27434069	27434092	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-0.5470199055810423	[5]	[2,2]	-6	hSpCas9	positive selection	3862524
27433708	27433731	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-1.7236342471828845	[2]	[0,0]	-9	hSpCas9	positive selection	3862525
27433771	27433794	2	+	26780180	A375	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	1.62110183381463	[]	[]	8	hSpCas9	negative selection	3973718
27433693	27433716	2	+	26780180	A375	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	2.50063377574667	[]	[]	9	hSpCas9	negative selection	3973719
27434748	27434771	2	-	26780180	A375	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	1.75368950155526	[]	[]	9	hSpCas9	negative selection	3973720
27434006	27434029	2	+	26780180	A375	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.43619276876311	[]	[]	1	hSpCas9	negative selection	3973721
27434714	27434737	2	+	26780180	A375	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	0.698474165839306	[]	[]	2	hSpCas9	negative selection	3973722
27434041	27434064	2	+	26780180	A375	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.605014625859017	[]	[]	2	hSpCas9	negative selection	3973723
27433771	27433794	2	+	26780180	HT29	viability (GeCKOv2 library)	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	1.67546111444877	[]	[]	8	hSpCas9	negative selection	4081684
27433693	27433716	2	+	26780180	HT29	viability (GeCKOv2 library)	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	2.97698096126286	[]	[]	9	hSpCas9	negative selection	4081685
27434748	27434771	2	-	26780180	HT29	viability (GeCKOv2 library)	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	2.25863914407151	[]	[]	9	hSpCas9	negative selection	4081686
27434006	27434029	2	+	26780180	HT29	viability (GeCKOv2 library)	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.0997680217725023	[]	[]	0	hSpCas9	negative selection	4081687
27434714	27434737	2	+	26780180	HT29	viability (GeCKOv2 library)	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	1.00263741459813	[]	[]	4	hSpCas9	negative selection	4081688
27434041	27434064	2	+	26780180	HT29	viability (GeCKOv2 library)	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.236865716135641	[]	[]	0	hSpCas9	negative selection	4081689
27434006	27434029	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	1.0455364472336157	[3]	[7,2]	9	hSpCas9	positive selection	4156278
27433716	27433739	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACACCTTCCTCTGTATCCATGG	NRBP1	ENSG00000115216	-0.12223938368988971	[4]	[2,2]	-3	hSpCas9	positive selection	4156279
27434041	27434064	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	-0.07166743198285563	[2]	[1,0]	-2	hSpCas9	positive selection	4156281
27434006	27434029	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.41689159580690016	[4]	[5,4,1,0]	3	hSpCas9	positive selection	4220300
27433716	27433739	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACACCTTCCTCTGTATCCATGG	NRBP1	ENSG00000115216	-0.2818622080734444	[4]	[3,2,1,0]	-4	hSpCas9	positive selection	4220301
27434041	27434064	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	1.2204411062697726	[2]	[0,3,3,3]	8	hSpCas9	positive selection	4220303
27433693	27433716	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.0579625596668521	[4]	[2,2]	-1	hSpCas9	positive selection	4286310
27434714	27434737	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-0.14915934871556047	[0]	[0,0]	-3	hSpCas9	positive selection	4286311
27433771	27433794	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.3860358651834291	[4]	[3,0]	-7	hSpCas9	positive selection	4286312
27434748	27434771	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.5285949813678792	[2]	[1,0]	-8	hSpCas9	positive selection	4350567
27434006	27434029	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.18116561739010015	[3]	[4,2]	3	hSpCas9	positive selection	4350568
27434041	27434064	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.5963937666667117	[3]	[4,4]	9	hSpCas9	positive selection	4350569
27433437	27433459	2	+	27760321	OCIAML3	viability	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	-1.2013665743806534	[503,454]	[145,184]	-8	hSpCas9	negative selection	4423458
27433674	27433696	2	+	27760321	OCIAML3	viability	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-1.2460030887797133	[205,166]	[58,63]	-8	hSpCas9	negative selection	4423459
27433694	27433716	2	+	27760321	OCIAML3	viability	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.4910749636616398	[276,275]	[74,79]	-8	hSpCas9	negative selection	4423460
27434748	27434770	2	-	27760321	OCIAML3	viability	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.1424237871445726	[309,281]	[63,157]	-7	hSpCas9	negative selection	4423461
27436813	27436835	2	+	27760321	OCIAML3	viability	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	0.6295260588984388	[551,510]	[630,658]	7	hSpCas9	negative selection	4423462
27433437	27433459	2	+	27760321	OCIAML2	viability	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	-1.2162718554369476	[503,454]	[133,209]	-8	hSpCas9	negative selection	4506921
27433674	27433696	2	+	27760321	OCIAML2	viability	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-1.4548072600160071	[205,166]	[49,60]	-8	hSpCas9	negative selection	4506922
27433694	27433716	2	+	27760321	OCIAML2	viability	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.0697859950629551	[276,275]	[80,140]	-7	hSpCas9	negative selection	4506923
27434748	27434770	2	-	27760321	OCIAML2	viability	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.5331874848183147	[309,281]	[86,76]	-8	hSpCas9	negative selection	4506924
27436813	27436835	2	+	27760321	OCIAML2	viability	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	-0.0810488186382223	[551,510]	[371,451]	-1	hSpCas9	negative selection	4506925
27433437	27433459	2	+	27760321	MV411	viability	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	0.10253829442544046	[503,454]	[364,300]	0	hSpCas9	negative selection	4590384
27433674	27433696	2	+	27760321	MV411	viability	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	0.19008703104898772	[205,166]	[211,30]	1	hSpCas9	negative selection	4590385
27433694	27433716	2	+	27760321	MV411	viability	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.16570517048851	[276,275]	[65,104]	-6	hSpCas9	negative selection	4590386
27434748	27434770	2	-	27760321	MV411	viability	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.05737980188671	[309,281]	[94,91]	-6	hSpCas9	negative selection	4590387
27436813	27436835	2	+	27760321	MV411	viability	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	-0.011253937775234923	[551,510]	[170,613]	0	hSpCas9	negative selection	4590388
27433437	27433459	2	+	27760321	HL60	viability	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	-0.92884440460725	[503,454]	[190,220]	-7	hSpCas9	negative selection	4673847
27433674	27433696	2	+	27760321	HL60	viability	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-1.1930495576328282	[205,166]	[58,73]	-8	hSpCas9	negative selection	4673848
27433694	27433716	2	+	27760321	HL60	viability	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.5060339252487567	[276,275]	[160,157]	-5	hSpCas9	negative selection	4673849
27434748	27434770	2	-	27760321	HL60	viability	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.6124657670038217	[309,281]	[159,155]	-6	hSpCas9	negative selection	4673850
27436813	27436835	2	+	27760321	HL60	viability	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	0.9258529712577239	[551,510]	[739,914]	8	hSpCas9	negative selection	4673851
27433437	27433459	2	+	27760321	HT1080	viability	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	-6.77091962223991	[454,354]	[0,1]	-9	hSpCas9	negative selection	4757310
27433674	27433696	2	+	27760321	HT1080	viability	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-5.891804334716809	[166,130]	[0,0]	-8	hSpCas9	negative selection	4757311
27433694	27433716	2	+	27760321	HT1080	viability	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-6.008360028135847	[275,215]	[1,0]	-9	hSpCas9	negative selection	4757312
27434748	27434770	2	-	27760321	HT1080	viability	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-6.643689686276161	[281,219]	[0,0]	-9	hSpCas9	negative selection	4757313
27436813	27436835	2	+	27760321	HT1080	viability	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	-1.9035374781036432	[510,398]	[78,14]	-6	hSpCas9	negative selection	4757314
27433437	27433459	2	+	27760321	HT29	viability after 7 days	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	-0.922789665986791	[454,354]	[332,226,271]	-8	hSpCas9	negative selection	4840773
27433674	27433696	2	+	27760321	HT29	viability after 7 days	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-0.30122008501002395	[166,130]	[231,81,162]	-4	hSpCas9	negative selection	4840774
27433694	27433716	2	+	27760321	HT29	viability after 7 days	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.7992733646877408	[275,215]	[58,22,182]	-9	hSpCas9	negative selection	4840775
27434748	27434770	2	-	27760321	HT29	viability after 7 days	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.9948285406249463	[281,219]	[156,233,95]	-8	hSpCas9	negative selection	4840776
27436813	27436835	2	+	27760321	HT29	viability after 7 days	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	-0.1133148133516308	[510,398]	[533,395,685]	-2	hSpCas9	negative selection	4840777
27433437	27433459	2	+	27760321	HT29	viability after 25 days	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	-3.2060743647280603	[454,354]	[30,109,5]	-8	hSpCas9	negative selection	4924236
27433674	27433696	2	+	27760321	HT29	viability after 25 days	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-4.405163275127158	[166,130]	[7,8,6]	-9	hSpCas9	negative selection	4924237
27433694	27433716	2	+	27760321	HT29	viability after 25 days	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-3.3376467489003394	[275,215]	[5,48,29]	-8	hSpCas9	negative selection	4924238
27434748	27434770	2	-	27760321	HT29	viability after 25 days	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-3.3592107755289913	[281,219]	[2,74,4]	-8	hSpCas9	negative selection	4924239
27436813	27436835	2	+	27760321	HT29	viability after 25 days	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	-0.2542081795544232	[510,398]	[328,471,521]	-3	hSpCas9	negative selection	4924240
27433437	27433459	2	+	27760321	HT29	viability after 22 days	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	-2.3280325935006663	[454,354]	[22,125,132]	-8	hSpCas9	negative selection	5007699
27433674	27433696	2	+	27760321	HT29	viability after 22 days	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-2.4627691493104833	[166,130]	[85,4,0]	-8	hSpCas9	negative selection	5007700
27433694	27433716	2	+	27760321	HT29	viability after 22 days	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-3.206527208244709	[275,215]	[9,51,30]	-8	hSpCas9	negative selection	5007701
27434748	27434770	2	-	27760321	HT29	viability after 22 days	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-3.092487646465814	[281,219]	[36,27,36]	-8	hSpCas9	negative selection	5007702
27436813	27436835	2	+	27760321	HT29	viability after 22 days	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	-0.002127875296983772	[510,398]	[387,813,375]	0	hSpCas9	negative selection	5007703
27433437	27433459	2	+	27760321	HT29	viability after 19 days	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	-3.2679432972261844	[454,354]	[24,73,42]	-9	hSpCas9	negative selection	5091162
27433674	27433696	2	+	27760321	HT29	viability after 19 days	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-2.320288672070117	[166,130]	[6,70,21]	-8	hSpCas9	negative selection	5091163
27433694	27433716	2	+	27760321	HT29	viability after 19 days	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-4.687444566198288	[275,215]	[2,19,8]	-9	hSpCas9	negative selection	5091164
27434748	27434770	2	-	27760321	HT29	viability after 19 days	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-4.021005649177162	[281,219]	[33,9,10]	-9	hSpCas9	negative selection	5091165
27436813	27436835	2	+	27760321	HT29	viability after 19 days	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	-0.09756200574865326	[510,398]	[639,620,223]	-1	hSpCas9	negative selection	5091166
27433437	27433459	2	+	27760321	HT29	viability after 16 days	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	-1.9077029235141096	[454,354]	[83,150,122]	-8	hSpCas9	negative selection	5174625
27433674	27433696	2	+	27760321	HT29	viability after 16 days	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-4.362816691209526	[166,130]	[23,0,0]	-9	hSpCas9	negative selection	5174626
27433694	27433716	2	+	27760321	HT29	viability after 16 days	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-3.9597713088037443	[275,215]	[6,19,24]	-9	hSpCas9	negative selection	5174627
27434748	27434770	2	-	27760321	HT29	viability after 16 days	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-2.0347104414883552	[281,219]	[74,37,93]	-8	hSpCas9	negative selection	5174628
27436813	27436835	2	+	27760321	HT29	viability after 16 days	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	-0.17171738059296576	[510,398]	[446,424,483]	-2	hSpCas9	negative selection	5174629
27433437	27433459	2	+	27760321	HT29	viability after 13 days	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	-1.3013745671543604	[454,354]	[122,189,254]	-8	hSpCas9	negative selection	5258088
27433674	27433696	2	+	27760321	HT29	viability after 13 days	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-2.88793367340837	[166,130]	[37,7,23]	-9	hSpCas9	negative selection	5258089
27433694	27433716	2	+	27760321	HT29	viability after 13 days	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-2.930569335956672	[275,215]	[20,47,42]	-9	hSpCas9	negative selection	5258090
27434748	27434770	2	-	27760321	HT29	viability after 13 days	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.8254136328453487	[281,219]	[93,113,40]	-8	hSpCas9	negative selection	5258091
27436813	27436835	2	+	27760321	HT29	viability after 13 days	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	0.032046285119274764	[510,398]	[570,695,362]	0	hSpCas9	negative selection	5258092
27433437	27433459	2	+	27760321	HT29	viability after 10 days	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	-0.9356968568670182	[454,354]	[280,396,121]	-7	hSpCas9	negative selection	5341551
27433674	27433696	2	+	27760321	HT29	viability after 10 days	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-2.7902329692395944	[166,130]	[30,10,37]	-9	hSpCas9	negative selection	5341552
27433694	27433716	2	+	27760321	HT29	viability after 10 days	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.1067689241689096	[275,215]	[141,184,102]	-8	hSpCas9	negative selection	5341553
27434748	27434770	2	-	27760321	HT29	viability after 10 days	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.3161822551459297	[281,219]	[116,78,178]	-8	hSpCas9	negative selection	5341554
27436813	27436835	2	+	27760321	HT29	viability after 10 days	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	-0.08158660824458769	[510,398]	[624,566,421]	-1	hSpCas9	negative selection	5341555
27433437	27433459	2	+	27760321	MOLM13	viability	TTTTGGAAGAGTCGCCCTGTGG	NRBP1	ENSG00000115216	0.6983792112044698	[503,454]	[80,742]	5	hSpCas9	negative selection	5425014
27433674	27433696	2	+	27760321	MOLM13	viability	TGAATCAACGGAATGTACCAGG	NRBP1	ENSG00000115216	-1.905280210203955	[205,166]	[21,32]	-8	hSpCas9	negative selection	5425015
27433694	27433716	2	+	27760321	MOLM13	viability	GGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-6.233110533364414	[276,275]	[0,2]	-9	hSpCas9	negative selection	5425016
27434748	27434770	2	-	27760321	MOLM13	viability	TACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.8603003511490951	[309,281]	[38,136]	-5	hSpCas9	negative selection	5425017
27436813	27436835	2	+	27760321	MOLM13	viability	ACTTCTTTGCACCAGAGTATGG	NRBP1	ENSG00000115216	0.14300931019385116	[551,510]	[476,206]	1	hSpCas9	negative selection	5425018
27428637	27428660	2	+	27661255	K562	viability	GCTGCGGAGCGCAGCTGTGAGGG	NRBP1	ENSG00000115216	-2.816204130310692	[859,757]	[105,79]	-9	dCas9-KRAB	negative selection	5497465
27428655	27428678	2	+	27661255	K562	viability	GAGGGAGTCGCTGTGATCCGGGG	NRBP1	ENSG00000115216	-2.6271118664057482	[1164,944]	[164,112]	-9	dCas9-KRAB	negative selection	5497466
27429072	27429095	2	+	27661255	K562	viability	GGCGGCCTGCGGAAGCTCGGCGG	NRBP1	ENSG00000115216	-0.7721119999740682	[691,648]	[320,307]	-8	dCas9-KRAB	negative selection	5497467
27428588	27428611	2	-	27661255	K562	viability	GCGGCGCCCGGACCAACGATGGG	NRBP1	ENSG00000115216	-0.1102404110444899	[185,222]	[179,125]	-4	dCas9-KRAB	negative selection	5497468
27433693	27433716	2	+	27260156	BXPC3	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.653278864965352	[1001]	[559,578,713,846]	-8	hSpCas9	negative selection	5558770
27434714	27434737	2	+	27260156	BXPC3	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-2.6529460981831283	[56]	[2,15,10,7]	-9	hSpCas9	negative selection	5558771
27433771	27433794	2	+	27260156	BXPC3	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.34144894488010613	[1036]	[860,819,872,865]	-6	hSpCas9	negative selection	5558772
27434748	27434771	2	-	27260156	BXPC3	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.6605239663299648	[393]	[165,236,339,317]	-8	hSpCas9	negative selection	5623027
27434006	27434029	2	+	27260156	BXPC3	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.14158045419741072	[776]	[882,803,848,1069]	3	hSpCas9	negative selection	5623028
27434041	27434064	2	+	27260156	BXPC3	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.22611827153251784	[711]	[915,787,880,894]	5	hSpCas9	negative selection	5623029
27433693	27433716	2	+	27260156	A673	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.3870815807523187	[1001]	[994,982,822,882]	-7	hSpCas9	negative selection	5680021
27434714	27434737	2	+	27260156	A673	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-0.10289082173459585	[56]	[72,45,76,59]	-3	hSpCas9	negative selection	5680022
27433771	27433794	2	+	27260156	A673	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.313592744668716	[1036]	[1153,913,982,972]	-6	hSpCas9	negative selection	5680023
27434748	27434771	2	-	27260156	A673	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.4772344212789217	[393]	[310,348,208,495]	-8	hSpCas9	negative selection	5744278
27434006	27434029	2	+	27260156	A673	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.23661945482841795	[776]	[1318,974,928,1207]	5	hSpCas9	negative selection	5744279
27434041	27434064	2	+	27260156	A673	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.02932927732866064	[711]	[929,947,757,856]	0	hSpCas9	negative selection	5744280
27433693	27433716	2	+	27260156	A375	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.7393980647295867	[1001]	[736,697,478,866]	-7	hSpCas9	negative selection	5801272
27434714	27434737	2	+	27260156	A375	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-2.675462814554936	[56]	[0,23,12,5]	-9	hSpCas9	negative selection	5801273
27433771	27433794	2	+	27260156	A375	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.6301041276803497	[1036]	[644,1047,777,701]	-7	hSpCas9	negative selection	5801274
27434748	27434771	2	-	27260156	A375	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.7003940941420144	[393]	[138,143,176,109]	-9	hSpCas9	negative selection	5865529
27434006	27434029	2	+	27260156	A375	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.5343932957191448	[776]	[1023,1751,1255,1282]	7	hSpCas9	negative selection	5865530
27434041	27434064	2	+	27260156	A375	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.6752601512547848	[711]	[1682,1615,1457,671]	8	hSpCas9	negative selection	5865531
27433693	27433716	2	+	27260156	COLO741	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.36017716171130754	[1001]	[1022,997,972]	-6	hSpCas9	negative selection	5922523
27434714	27434737	2	+	27260156	COLO741	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-1.5066817646436306	[56]	[26,38,11]	-9	hSpCas9	negative selection	5922524
27433771	27433794	2	+	27260156	COLO741	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.2689618849661116	[1036]	[1317,973,1027]	-5	hSpCas9	negative selection	5922525
27434748	27434771	2	-	27260156	COLO741	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	0.04477052902954057	[393]	[684,499,394]	0	hSpCas9	negative selection	5986780
27434006	27434029	2	+	27260156	COLO741	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.047333161933592716	[776]	[1237,1094,778]	1	hSpCas9	negative selection	5986781
27434041	27434064	2	+	27260156	COLO741	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.0063004723436564936	[711]	[1080,856,821]	0	hSpCas9	negative selection	5986782
27433693	27433716	2	+	27260156	CAL120	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.5463305150792932	[1001]	[899,700,964]	-7	hSpCas9	negative selection	6043774
27434714	27434737	2	+	27260156	CAL120	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-2.8044882642025906	[56]	[13,4,11]	-9	hSpCas9	negative selection	6043775
27433771	27433794	2	+	27260156	CAL120	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.6102070931754875	[1036]	[906,735,900]	-7	hSpCas9	negative selection	6043776
27434748	27434771	2	-	27260156	CAL120	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.9066509897124834	[393]	[377,217,206]	-8	hSpCas9	negative selection	6108031
27434006	27434029	2	+	27260156	CAL120	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.18278879474713416	[776]	[972,962,1332]	2	hSpCas9	negative selection	6108032
27434041	27434064	2	+	27260156	CAL120	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.33338264141775387	[711]	[1228,992,1142]	5	hSpCas9	negative selection	6108033
27433693	27433716	2	+	27260156	CADOES1	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.651092676353975	[1001]	[614,491,710,553]	-8	hSpCas9	negative selection	6165025
27434714	27434737	2	+	27260156	CADOES1	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-1.2762345903134786	[56]	[25,5,20,34]	-9	hSpCas9	negative selection	6165026
27433771	27433794	2	+	27260156	CADOES1	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.48653717709222144	[1036]	[663,643,666,781]	-7	hSpCas9	negative selection	6165027
27434748	27434771	2	-	27260156	CADOES1	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.5746433331026566	[393]	[172,186,383,239]	-7	hSpCas9	negative selection	6229282
27434006	27434029	2	+	27260156	CADOES1	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.4480909085512699	[776]	[905,1165,709,1168]	7	hSpCas9	negative selection	6229283
27434041	27434064	2	+	27260156	CADOES1	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.5872993196954958	[711]	[884,1158,973,960]	8	hSpCas9	negative selection	6229284
27433693	27433716	2	+	27260156	EWS502	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.45230036072416124	[1001]	[569,733,988,840]	-6	hSpCas9	negative selection	6286276
27434714	27434737	2	+	27260156	EWS502	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-2.0638565819917254	[56]	[39,7,0,4]	-9	hSpCas9	negative selection	6286277
27433771	27433794	2	+	27260156	EWS502	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.3213013343358615	[1036]	[841,628,1097,967]	-5	hSpCas9	negative selection	6286278
27434748	27434771	2	-	27260156	EWS502	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.5265212036608795	[393]	[288,397,203,258]	-7	hSpCas9	negative selection	6350533
27434006	27434029	2	+	27260156	EWS502	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.2958683838394507	[776]	[716,987,1069,1321]	5	hSpCas9	negative selection	6350534
27434041	27434064	2	+	27260156	EWS502	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.3892075031189536	[711]	[765,835,1244,1147]	6	hSpCas9	negative selection	6350535
27433693	27433716	2	+	27260156	EW8	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.71632532105222	[1001]	[491,453,499,527]	-8	hSpCas9	negative selection	6407527
27434714	27434737	2	+	27260156	EW8	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-1.3001940859146934	[56]	[1,12,18,38]	-9	hSpCas9	negative selection	6407528
27433771	27433794	2	+	27260156	EW8	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.21580282048330035	[1036]	[874,704,647,693]	-4	hSpCas9	negative selection	6407529
27434748	27434771	2	-	27260156	EW8	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.068894446828193	[393]	[97,199,161,140]	-9	hSpCas9	negative selection	6471784
27434006	27434029	2	+	27260156	EW8	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.2764516099487986	[776]	[868,785,646,777]	5	hSpCas9	negative selection	6471785
27434041	27434064	2	+	27260156	EW8	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.49266169577735675	[711]	[1032,1013,587,673]	8	hSpCas9	negative selection	6471786
27433693	27433716	2	+	27260156	CORL105	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.6119292931587902	[1001]	[746,812,833,684]	-8	hSpCas9	negative selection	6528778
27434714	27434737	2	+	27260156	CORL105	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	0.2578833867021726	[56]	[106,69,33,101]	5	hSpCas9	negative selection	6528779
27433771	27433794	2	+	27260156	CORL105	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.5764436985206977	[1036]	[771,710,1037,770]	-8	hSpCas9	negative selection	6528780
27434748	27434771	2	-	27260156	CORL105	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.19769735614514045	[393]	[410,358,510,345]	-4	hSpCas9	negative selection	6593035
27434006	27434029	2	+	27260156	CORL105	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.2582710636707769	[776]	[964,1182,1317,915]	5	hSpCas9	negative selection	6593036
27434041	27434064	2	+	27260156	CORL105	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.3252925419136048	[711]	[1093,932,1302,891]	6	hSpCas9	negative selection	6593037
27433693	27433716	2	+	27260156	HS294T	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.7104986807057594	[1001]	[212,224,238,278]	-7	hSpCas9	negative selection	6650029
27434714	27434737	2	+	27260156	HS294T	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-2.117246483433763	[56]	[3,1,6,7]	-9	hSpCas9	negative selection	6650030
27433771	27433794	2	+	27260156	HS294T	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.06582166812957668	[1036]	[212,462,349,545]	-1	hSpCas9	negative selection	6650031
27434748	27434771	2	-	27260156	HS294T	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.0483399811748173	[393]	[54,37,82,130]	-9	hSpCas9	negative selection	6714286
27434006	27434029	2	+	27260156	HS294T	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	-0.09398261445982303	[776]	[251,240,265,387]	-1	hSpCas9	negative selection	6714287
27434041	27434064	2	+	27260156	HS294T	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.03305390559183663	[711]	[315,265,243,299]	0	hSpCas9	negative selection	6714288
27433693	27433716	2	+	27260156	HCC44	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.6894497449224368	[1001]	[702,611,597,880]	-7	hSpCas9	negative selection	6771280
27434714	27434737	2	+	27260156	HCC44	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-2.297986290161175	[56]	[17,15,4,11]	-9	hSpCas9	negative selection	6771281
27433771	27433794	2	+	27260156	HCC44	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.1793997968747867	[1036]	[1259,743,1203,1017]	-3	hSpCas9	negative selection	6771282
27434748	27434771	2	-	27260156	HCC44	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.3593676613605306	[393]	[164,136,197,200]	-9	hSpCas9	negative selection	6835537
27434006	27434029	2	+	27260156	HCC44	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.23914224460092515	[776]	[1346,714,1066,1088]	4	hSpCas9	negative selection	6835538
27434041	27434064	2	+	27260156	HCC44	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.3480748990963336	[711]	[1095,897,975,1133]	5	hSpCas9	negative selection	6835539
27433693	27433716	2	+	27260156	G402	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.5026386246641634	[1001]	[1006,1251,562,678]	-6	hSpCas9	negative selection	6892531
27434714	27434737	2	+	27260156	G402	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-0.26865486858048016	[56]	[15,14,107,81]	-3	hSpCas9	negative selection	6892532
27433771	27433794	2	+	27260156	G402	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.8098939765774823	[1036]	[1161,782,507,508]	-7	hSpCas9	negative selection	6892533
27434748	27434771	2	-	27260156	G402	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.10031008462097174	[393]	[639,227,702,245]	-1	hSpCas9	negative selection	6956788
27434006	27434029	2	+	27260156	G402	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.8797042677587525	[776]	[3332,1017,1711,1125]	9	hSpCas9	negative selection	6956789
27434041	27434064	2	+	27260156	G402	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.43151550482671086	[711]	[1301,1261,1261,893]	5	hSpCas9	negative selection	6956790
27433693	27433716	2	+	27260156	L33	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.14698776484926523	[1001]	[866,417,508,922]	-3	hSpCas9	negative selection	7013782
27434714	27434737	2	+	27260156	L33	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-1.4064021724274616	[56]	[16,10,6,30]	-9	hSpCas9	negative selection	7013783
27433771	27433794	2	+	27260156	L33	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.084669629171501	[1036]	[1048,434,593,854]	-2	hSpCas9	negative selection	7013784
27434748	27434771	2	-	27260156	L33	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.3116475573899753	[393]	[434,89,217,265]	-6	hSpCas9	negative selection	7078039
27434006	27434029	2	+	27260156	L33	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	-0.004696610823145098	[776]	[675,322,476,875]	0	hSpCas9	negative selection	7078040
27434041	27434064	2	+	27260156	L33	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.10507143681782805	[711]	[673,358,459,782]	2	hSpCas9	negative selection	7078041
27433693	27433716	2	+	27260156	K562	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.1088186258730945	[1001]	[507,412,337,397]	-8	hSpCas9	negative selection	7135033
27434714	27434737	2	+	27260156	K562	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-3.0724885823398385	[56]	[0,1,19,0]	-9	hSpCas9	negative selection	7135034
27433771	27433794	2	+	27260156	K562	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.6673623367693212	[1036]	[810,647,526,375]	-7	hSpCas9	negative selection	7135035
27434748	27434771	2	-	27260156	K562	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.8775387247860192	[393]	[218,106,209,218]	-7	hSpCas9	negative selection	7199290
27434006	27434029	2	+	27260156	K562	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.18449093314418175	[776]	[1058,712,538,832]	2	hSpCas9	negative selection	7199291
27434041	27434064	2	+	27260156	K562	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.3893937527263246	[711]	[822,831,976,690]	5	hSpCas9	negative selection	7199292
27433693	27433716	2	+	27260156	HT29	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.8756913404922012	[1001]	[708,688,476,767]	-8	hSpCas9	negative selection	7256284
27434714	27434737	2	+	27260156	HT29	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-1.5587560941115797	[56]	[25,25,15,25]	-9	hSpCas9	negative selection	7256285
27433771	27433794	2	+	27260156	HT29	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.33452590045934705	[1036]	[1134,985,1025,869]	-6	hSpCas9	negative selection	7256286
27434748	27434771	2	-	27260156	HT29	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.0811331443541796	[393]	[189,246,213,248]	-9	hSpCas9	negative selection	7320541
27434006	27434029	2	+	27260156	HT29	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.2056695818895098	[776]	[1246,1053,1145,930]	4	hSpCas9	negative selection	7320542
27434041	27434064	2	+	27260156	HT29	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.45561040432783895	[711]	[1350,1251,991,1164]	8	hSpCas9	negative selection	7320543
27433693	27433716	2	+	27260156	MHHES1	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.6021240587327095	[1001]	[789,723,748,705]	-8	hSpCas9	negative selection	7377535
27434714	27434737	2	+	27260156	MHHES1	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-0.3127860488053469	[56]	[80,28,96,9]	-5	hSpCas9	negative selection	7377536
27433771	27433794	2	+	27260156	MHHES1	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.3064323627480272	[1036]	[950,1014,973,846]	-5	hSpCas9	negative selection	7377537
27434748	27434771	2	-	27260156	MHHES1	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.9826184060533146	[393]	[173,236,154,302]	-9	hSpCas9	negative selection	7441792
27434006	27434029	2	+	27260156	MHHES1	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.3968126721663803	[776]	[1134,1385,1060,1045]	7	hSpCas9	negative selection	7441793
27434041	27434064	2	+	27260156	MHHES1	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.5495302460044099	[711]	[1407,1386,1092,894]	8	hSpCas9	negative selection	7441794
27433693	27433716	2	+	27260156	MEWO	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.22162465818019983	[1001]	[1031,768,654]	-5	hSpCas9	negative selection	7498786
27434714	27434737	2	+	27260156	MEWO	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-0.10733051015335571	[56]	[41,58,45]	-2	hSpCas9	negative selection	7498787
27433771	27433794	2	+	27260156	MEWO	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.05644505873415695	[1036]	[1017,958,837]	-1	hSpCas9	negative selection	7498788
27434748	27434771	2	-	27260156	MEWO	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.572072368791073	[393]	[285,279,184]	-8	hSpCas9	negative selection	7563043
27434006	27434029	2	+	27260156	MEWO	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	-0.09075061989008126	[776]	[781,670,613]	-2	hSpCas9	negative selection	7563044
27434041	27434064	2	+	27260156	MEWO	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.1245988759875124	[711]	[916,607,690]	2	hSpCas9	negative selection	7563045
27433693	27433716	2	+	27260156	LNCAPCLONEFGC	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.8921480510094607	[1001]	[311,548,600,509]	-8	hSpCas9	negative selection	7620037
27434714	27434737	2	+	27260156	LNCAPCLONEFGC	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-1.1504455242231009	[56]	[19,4,27,41]	-9	hSpCas9	negative selection	7620038
27433771	27433794	2	+	27260156	LNCAPCLONEFGC	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.4950336429442256	[1036]	[878,669,731,389]	-6	hSpCas9	negative selection	7620039
27434748	27434771	2	-	27260156	LNCAPCLONEFGC	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.2785041646780222	[393]	[163,128,178,121]	-9	hSpCas9	negative selection	7684294
27434006	27434029	2	+	27260156	LNCAPCLONEFGC	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.47363282894212655	[776]	[1077,734,957,1148]	7	hSpCas9	negative selection	7684295
27434041	27434064	2	+	27260156	LNCAPCLONEFGC	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.4584151102756834	[711]	[1156,697,869,823]	7	hSpCas9	negative selection	7684296
27433693	27433716	2	+	27260156	PANC0327	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.1177095505779393	[1001]	[349,354,545,391]	-8	hSpCas9	negative selection	7741288
27434714	27434737	2	+	27260156	PANC0327	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-4.6387823117987645	[56]	[1,2,0,1]	-9	hSpCas9	negative selection	7741289
27433771	27433794	2	+	27260156	PANC0327	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.6363742179501547	[1036]	[608,580,534,647]	-7	hSpCas9	negative selection	7741290
27434748	27434771	2	-	27260156	PANC0327	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.9600903790036467	[393]	[112,372,70,131]	-8	hSpCas9	negative selection	7805545
27434006	27434029	2	+	27260156	PANC0327	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.09669753989465402	[776]	[613,836,702,774]	1	hSpCas9	negative selection	7805546
27434041	27434064	2	+	27260156	PANC0327	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.42325756347281673	[711]	[1091,575,724,1053]	6	hSpCas9	negative selection	7805547
27433693	27433716	2	+	27260156	NCIH2009	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.863874924571555	[1001]	[461,356,349]	-9	hSpCas9	negative selection	7862539
27434714	27434737	2	+	27260156	NCIH2009	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-3.7087599415542076	[56]	[9,7,0]	-9	hSpCas9	negative selection	7862540
27433771	27433794	2	+	27260156	NCIH2009	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.7905131186162933	[1036]	[916,681,930]	-7	hSpCas9	negative selection	7862541
27434748	27434771	2	-	27260156	NCIH2009	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-2.0060788365405924	[393]	[102,145,154]	-9	hSpCas9	negative selection	7926796
27434006	27434029	2	+	27260156	NCIH2009	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.031457634934699996	[776]	[1457,864,1076]	0	hSpCas9	negative selection	7926797
27434041	27434064	2	+	27260156	NCIH2009	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.5081220029102015	[711]	[1510,1134,1619]	7	hSpCas9	negative selection	7926798
27433693	27433716	2	+	27260156	NCIH1373	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.181208674877511	[1001]	[797,486,349,101]	-8	hSpCas9	negative selection	7983790
27434714	27434737	2	+	27260156	NCIH1373	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-3.8115271921622638	[56]	[12,1,0,0]	-9	hSpCas9	negative selection	7983791
27433771	27433794	2	+	27260156	NCIH1373	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.4086564014665669	[1036]	[1490,642,660,216]	-4	hSpCas9	negative selection	7983792
27434748	27434771	2	-	27260156	NCIH1373	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-2.09649638652677	[393]	[92,55,78,50]	-9	hSpCas9	negative selection	8048047
27434006	27434029	2	+	27260156	NCIH1373	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.798642087851025	[776]	[2187,1525,938,397]	7	hSpCas9	negative selection	8048048
27434041	27434064	2	+	27260156	NCIH1373	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.851610365032475	[711]	[1564,1037,1392,484]	8	hSpCas9	negative selection	8048049
27433693	27433716	2	+	27260156	PATU8902	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.3741684062591086	[1001]	[384,540,575,652]	-8	hSpCas9	negative selection	8105041
27434714	27434737	2	+	27260156	PATU8902	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-5.73817063399853	[56]	[1,1,0,0]	-9	hSpCas9	negative selection	8105042
27433771	27433794	2	+	27260156	PATU8902	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-1.16491227218815	[1036]	[692,621,430,911]	-8	hSpCas9	negative selection	8105043
27434748	27434771	2	-	27260156	PATU8902	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-2.369792741269354	[393]	[172,111,63,81]	-9	hSpCas9	negative selection	8169298
27434006	27434029	2	+	27260156	PATU8902	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.6284125454207876	[776]	[1417,1963,1493,1876]	6	hSpCas9	negative selection	8169299
27434041	27434064	2	+	27260156	PATU8902	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.6937076081242198	[711]	[1827,1536,1150,2054]	7	hSpCas9	negative selection	8169300
27433693	27433716	2	+	27260156	PANC1	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.588929789805227	[1001]	[379,776,519,636]	-7	hSpCas9	negative selection	8226292
27434714	27434737	2	+	27260156	PANC1	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-1.8577614250204073	[56]	[31,17,2,2]	-9	hSpCas9	negative selection	8226293
27433771	27433794	2	+	27260156	PANC1	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.47267736958072804	[1036]	[572,1050,585,461]	-6	hSpCas9	negative selection	8226294
27434748	27434771	2	-	27260156	PANC1	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.7434486611985898	[393]	[168,256,234,162]	-8	hSpCas9	negative selection	8290549
27434006	27434029	2	+	27260156	PANC1	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.429420290063117	[776]	[660,1175,1037,786]	7	hSpCas9	negative selection	8290550
27434041	27434064	2	+	27260156	PANC1	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.529366343176615	[711]	[993,1150,785,671]	8	hSpCas9	negative selection	8290551
27433693	27433716	2	+	27260156	PANC0813	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.4040133202797644	[1001]	[567,498,399,328]	-9	hSpCas9	negative selection	8347543
27434714	27434737	2	+	27260156	PANC0813	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-2.7136940008513157	[56]	[19,8,7,4]	-9	hSpCas9	negative selection	8347544
27433771	27433794	2	+	27260156	PANC0813	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.6626368948708639	[1036]	[816,904,705,658]	-7	hSpCas9	negative selection	8347545
27434748	27434771	2	-	27260156	PANC0813	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.5014528060200467	[393]	[153,187,170,140]	-9	hSpCas9	negative selection	8411800
27434006	27434029	2	+	27260156	PANC0813	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.2173778506860755	[776]	[1095,1087,886,1167]	3	hSpCas9	negative selection	8411801
27434041	27434064	2	+	27260156	PANC0813	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.10851716853082016	[711]	[944,1061,799,806]	1	hSpCas9	negative selection	8411802
27433693	27433716	2	+	27260156	RDES	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.2507837447550231	[1001]	[763,945,1057,1154]	-4	hSpCas9	negative selection	8468794
27434714	27434737	2	+	27260156	RDES	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-1.4980980951900245	[56]	[18,10,26,39]	-9	hSpCas9	negative selection	8468795
27433771	27433794	2	+	27260156	RDES	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.44270824531702724	[1036]	[792,882,663,1199]	-6	hSpCas9	negative selection	8468796
27434748	27434771	2	-	27260156	RDES	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.31161407958025533	[393]	[365,343,329,415]	-5	hSpCas9	negative selection	8533051
27434006	27434029	2	+	27260156	RDES	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.4671330933758826	[776]	[983,1177,1355,1488]	7	hSpCas9	negative selection	8533052
27434041	27434064	2	+	27260156	RDES	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.5255262297428919	[711]	[981,964,1183,1689]	8	hSpCas9	negative selection	8533053
27433693	27433716	2	+	27260156	PC3	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.2611517236832258	[1001]	[527,652,1253,1138]	-5	hSpCas9	negative selection	8590045
27434714	27434737	2	+	27260156	PC3	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-0.7418801805051936	[56]	[44,32,40,6]	-9	hSpCas9	negative selection	8590046
27433771	27433794	2	+	27260156	PC3	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.045748763858100894	[1036]	[709,1126,1181,1068]	-1	hSpCas9	negative selection	8590047
27434748	27434771	2	-	27260156	PC3	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.03066421809055725	[393]	[241,569,415,331]	0	hSpCas9	negative selection	8654302
27434006	27434029	2	+	27260156	PC3	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.17841423471041185	[776]	[692,853,1035,963]	4	hSpCas9	negative selection	8654303
27434041	27434064	2	+	27260156	PC3	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	-0.11039805927036439	[711]	[498,480,1116,718]	-2	hSpCas9	negative selection	8654304
27433693	27433716	2	+	27260156	PATU8988T	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.9458682132349991	[1001]	[505,302,660,520]	-8	hSpCas9	negative selection	8711296
27434714	27434737	2	+	27260156	PATU8988T	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-2.0114923388371357	[56]	[6,14,15,16]	-9	hSpCas9	negative selection	8711297
27433771	27433794	2	+	27260156	PATU8988T	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.26343482752970027	[1036]	[795,787,949,795]	-4	hSpCas9	negative selection	8711298
27434748	27434771	2	-	27260156	PATU8988T	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.6278819097432558	[393]	[55,187,98,158]	-9	hSpCas9	negative selection	8775553
27434006	27434029	2	+	27260156	PATU8988T	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	-0.008609513793672696	[776]	[660,1022,635,687]	0	hSpCas9	negative selection	8775554
27434041	27434064	2	+	27260156	PATU8988T	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.4343925528278584	[711]	[582,1208,1056,890]	7	hSpCas9	negative selection	8775555
27433693	27433716	2	+	27260156	T47D	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.5247313453027594	[1001]	[831,740,878,797]	-8	hSpCas9	negative selection	8832547
27434714	27434737	2	+	27260156	T47D	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-0.7476090764278318	[56]	[71,31,22,31]	-9	hSpCas9	negative selection	8832548
27433771	27433794	2	+	27260156	T47D	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.2849317805548971	[1036]	[1077,891,1046,955]	-6	hSpCas9	negative selection	8832549
27434748	27434771	2	-	27260156	T47D	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.5015523568177614	[393]	[337,307,310,341]	-8	hSpCas9	negative selection	8896804
27434006	27434029	2	+	27260156	T47D	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.2792016787100262	[776]	[958,1058,1064,1320]	6	hSpCas9	negative selection	8896805
27434041	27434064	2	+	27260156	T47D	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.2483598889640427	[711]	[1016,881,1017,1033]	5	hSpCas9	negative selection	8896806
27433693	27433716	2	+	27260156	SU8686	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-1.3844019214528216	[1001]	[423,275,385,453]	-9	hSpCas9	negative selection	8953798
27434714	27434737	2	+	27260156	SU8686	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-2.2793104480685082	[56]	[11,19,7,3]	-9	hSpCas9	negative selection	8953799
27433771	27433794	2	+	27260156	SU8686	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.4621604888356633	[1036]	[612,794,867,709]	-6	hSpCas9	negative selection	8953800
27434748	27434771	2	-	27260156	SU8686	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-1.3620484985188352	[393]	[107,179,171,147]	-9	hSpCas9	negative selection	9018055
27434006	27434029	2	+	27260156	SU8686	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.3630890003067675	[776]	[1001,872,889,1242]	6	hSpCas9	negative selection	9018056
27434041	27434064	2	+	27260156	SU8686	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.4396072758661079	[711]	[849,1075,918,975]	7	hSpCas9	negative selection	9018057
27433693	27433716	2	+	27260156	SKES1	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.16481852106068307	[1001]	[784,1053,888,839]	-4	hSpCas9	negative selection	9075049
27434714	27434737	2	+	27260156	SKES1	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-0.3838026252587978	[56]	[39,27,56,45]	-7	hSpCas9	negative selection	9075050
27433771	27433794	2	+	27260156	SKES1	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.26355591304863935	[1036]	[1031,957,612,871]	-5	hSpCas9	negative selection	9075051
27434748	27434771	2	-	27260156	SKES1	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.33158775882682434	[393]	[346,351,333,231]	-6	hSpCas9	negative selection	9139306
27434006	27434029	2	+	27260156	SKES1	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.06707909459733652	[776]	[1046,865,735,649]	1	hSpCas9	negative selection	9139307
27434041	27434064	2	+	27260156	SKES1	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.2672359806139395	[711]	[729,838,1024,800]	5	hSpCas9	negative selection	9139308
27433693	27433716	2	+	27260156	TOV112D	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.3936233750489444	[1001]	[702,924,735,725]	-7	hSpCas9	negative selection	9196300
27434714	27434737	2	+	27260156	TOV112D	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-1.0133215518561771	[56]	[2,102,18,4]	-9	hSpCas9	negative selection	9196301
27433771	27433794	2	+	27260156	TOV112D	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.2520163599938523	[1036]	[1050,1148,522,847]	-5	hSpCas9	negative selection	9196302
27434748	27434771	2	-	27260156	TOV112D	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.1404092350317283	[393]	[265,503,416,274]	-3	hSpCas9	negative selection	9260557
27434006	27434029	2	+	27260156	TOV112D	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.07096060054532816	[776]	[923,845,754,760]	1	hSpCas9	negative selection	9260558
27434041	27434064	2	+	27260156	TOV112D	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.1785904498322145	[711]	[590,1004,945,717]	3	hSpCas9	negative selection	9260559
27433693	27433716	2	+	27260156	TC71	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.2670357354475881	[1001]	[936,771,854,1013]	-6	hSpCas9	negative selection	9317551
27434714	27434737	2	+	27260156	TC71	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-0.23679798099866112	[56]	[45,65,21,75]	-6	hSpCas9	negative selection	9317552
27433771	27433794	2	+	27260156	TC71	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.33313683374375014	[1036]	[824,913,738,1068]	-7	hSpCas9	negative selection	9317553
27434748	27434771	2	-	27260156	TC71	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.44531291206927204	[393]	[251,346,304,339]	-8	hSpCas9	negative selection	9381808
27434006	27434029	2	+	27260156	TC71	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.19192994004361597	[776]	[773,1067,968,1000]	5	hSpCas9	negative selection	9381809
27434041	27434064	2	+	27260156	TC71	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.12383585219123727	[711]	[840,672,930,880]	3	hSpCas9	negative selection	9381810
27433693	27433716	2	+	27260156	TC32	viability	AGGTATTGACAGTGCATACCTGG	NRBP1	ENSG00000115216	-0.3965829511480957	[1001]	[785,457,946,758]	-6	hSpCas9	negative selection	9438802
27434714	27434737	2	+	27260156	TC32	viability	TGTTCCAGGCATGGAAGCGTTGG	NRBP1	ENSG00000115216	-0.9826524051484329	[56]	[40,5,27,38]	-9	hSpCas9	negative selection	9438803
27433771	27433794	2	+	27260156	TC32	viability	ACGCAAGAACTACAAGCTGCAGG	NRBP1	ENSG00000115216	-0.2624632527348306	[1036]	[732,641,1151,806]	-5	hSpCas9	negative selection	9438804
27434748	27434771	2	-	27260156	TC32	viability	CTACTTACCTTAGGGCAGAGAGG	NRBP1	ENSG00000115216	-0.7125767231822252	[393]	[205,146,414,185]	-8	hSpCas9	negative selection	9503059
27434006	27434029	2	+	27260156	TC32	viability	GTTTGATAATCTGATTCAATTGG	NRBP1	ENSG00000115216	0.519019457986519	[776]	[1114,876,1173,1028]	8	hSpCas9	negative selection	9503060
27434041	27434064	2	+	27260156	TC32	viability	TTGTTAAGTTTCACAAATATTGG	NRBP1	ENSG00000115216	0.3951377162038956	[711]	[908,436,1247,1118]	7	hSpCas9	negative selection	9503061
27433263	27433286	2	+	27869803	HPAFII	viability after 27 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.4308319995353487	[323]	[37,199,NaN]	-3	hSpCas9	negative selection	9574635
27433711	27433734	2	-	27869803	HPAFII	viability after 27 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-3.0039196085768163	[171]	[7,13,NaN]	-9	hSpCas9	negative selection	9574636
27437291	27437314	2	+	27869803	HPAFII	viability after 27 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	0.6469519885271714	[89]	[114,39,NaN]	5	hSpCas9	negative selection	9574637
27439853	27439876	2	-	27869803	HPAFII	viability after 27 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-6.731523509097959	[293]	[1,0,NaN]	-9	hSpCas9	negative selection	9574638
27440917	27440940	2	-	27869803	HPAFII	viability after 27 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.2828019492913272	[202]	[42,124,NaN]	-2	hSpCas9	negative selection	9574639
27441144	27441167	2	+	27869803	HPAFII	viability after 27 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	0.7921074658531394	[212]	[236,157,NaN]	6	hSpCas9	negative selection	9574640
27433263	27433286	2	+	27869803	HPAFII	viability after 15 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-1.2738638838090575	[323]	[180,120,NaN]	-8	hSpCas9	negative selection	9657084
27433711	27433734	2	-	27869803	HPAFII	viability after 15 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-2.2811046415135676	[171]	[21,47,NaN]	-9	hSpCas9	negative selection	9657085
27437291	27437314	2	+	27869803	HPAFII	viability after 15 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	0.3170831089467949	[89]	[138,108,NaN]	3	hSpCas9	negative selection	9657086
27439853	27439876	2	-	27869803	HPAFII	viability after 15 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-5.253240307701595	[293]	[19,0,NaN]	-9	hSpCas9	negative selection	9657087
27440917	27440940	2	-	27869803	HPAFII	viability after 15 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.689911405242924	[202]	[338,359,NaN]	7	hSpCas9	negative selection	9657088
27441144	27441167	2	+	27869803	HPAFII	viability after 15 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	0.7213518056740664	[212]	[435,340,NaN]	7	hSpCas9	negative selection	9657089
27433263	27433286	2	+	27869803	ASPC1	viability after 36 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.6104006494719687	[1006]	[127,138,371]	-6	hSpCas9	negative selection	9739533
27433711	27433734	2	-	27869803	ASPC1	viability after 36 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-1.2254798157053575	[380]	[64,10,86]	-8	hSpCas9	negative selection	9739534
27437291	27437314	2	+	27869803	ASPC1	viability after 36 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-1.0450786638591423	[281]	[48,37,53]	-7	hSpCas9	negative selection	9739535
27439853	27439876	2	-	27869803	ASPC1	viability after 36 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-4.696801141899937	[806]	[21,6,5]	-9	hSpCas9	negative selection	9739536
27440917	27440940	2	-	27869803	ASPC1	viability after 36 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.5954200616672936	[493]	[350,197,243]	6	hSpCas9	negative selection	9739537
27441144	27441167	2	+	27869803	ASPC1	viability after 36 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.20499364277461493	[807]	[307,169,256]	-2	hSpCas9	negative selection	9739538
27433263	27433286	2	+	27869803	PATU8988S	viability after 35 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.6149667929466274	[659]	[200,145,NaN]	-6	hSpCas9	negative selection	9821982
27433711	27433734	2	-	27869803	PATU8988S	viability after 35 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.9173650922994836	[264]	[60,51,NaN]	-7	hSpCas9	negative selection	9821983
27437291	27437314	2	+	27869803	PATU8988S	viability after 35 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-0.32296752108347837	[249]	[76,83,NaN]	-3	hSpCas9	negative selection	9821984
27439853	27439876	2	-	27869803	PATU8988S	viability after 35 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-2.409676804235297	[705]	[58,47,NaN]	-9	hSpCas9	negative selection	9821985
27440917	27440940	2	-	27869803	PATU8988S	viability after 35 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.24056492747835367	[413]	[197,83,NaN]	-3	hSpCas9	negative selection	9821986
27441144	27441167	2	+	27869803	PATU8988S	viability after 35 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-1.093041298402247	[730]	[142,132,NaN]	-7	hSpCas9	negative selection	9821987
27433263	27433286	2	+	27869803	PATU8988S	viability after 31 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.5396838380695397	[659]	[184,175,NaN]	-5	hSpCas9	negative selection	9904431
27433711	27433734	2	-	27869803	PATU8988S	viability after 31 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-0.9578706663772816	[264]	[49,59,NaN]	-7	hSpCas9	negative selection	9904432
27437291	27437314	2	+	27869803	PATU8988S	viability after 31 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	-0.12338487787735763	[249]	[65,123,NaN]	-1	hSpCas9	negative selection	9904433
27439853	27439876	2	-	27869803	PATU8988S	viability after 31 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-2.359867110045472	[705]	[60,46,NaN]	-9	hSpCas9	negative selection	9904434
27440917	27440940	2	-	27869803	PATU8988S	viability after 31 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	0.0129381051055239	[413]	[199,123,NaN]	0	hSpCas9	negative selection	9904435
27441144	27441167	2	+	27869803	PATU8988S	viability after 31 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	-0.5672525923916666	[730]	[201,189,NaN]	-6	hSpCas9	negative selection	9904436
27433263	27433286	2	+	27869803	HPAFII	viability after 35 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	0.0791393353846952	[323]	[10,355,NaN]	0	hSpCas9	negative selection	9986880
27433711	27433734	2	-	27869803	HPAFII	viability after 35 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-2.8812400073142657	[171]	[0,23,NaN]	-8	hSpCas9	negative selection	9986881
27437291	27437314	2	+	27869803	HPAFII	viability after 35 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	0.19582003908839263	[89]	[70,30,NaN]	1	hSpCas9	negative selection	9986882
27439853	27439876	2	-	27869803	HPAFII	viability after 35 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-7.21758379183969	[293]	[0,0,NaN]	-9	hSpCas9	negative selection	9986883
27440917	27440940	2	-	27869803	HPAFII	viability after 35 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.06110870949866004	[202]	[50,151,NaN]	0	hSpCas9	negative selection	9986884
27441144	27441167	2	+	27869803	HPAFII	viability after 35 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	0.6486969448402229	[212]	[153,185,NaN]	4	hSpCas9	negative selection	9986885
27433263	27433286	2	+	27869803	HPAFII	viability after 31 days	TTCCTTCCAGCATGTCGGAGGGG	NRBP1	ENSG00000115216	-0.26909809921006206	[323]	[47,262,NaN]	-2	hSpCas9	negative selection	10069329
27433711	27433734	2	-	27869803	HPAFII	viability after 31 days	CTTCCTCTGTATCCATGGCCAGG	NRBP1	ENSG00000115216	-6.028689614472482	[171]	[0,1,NaN]	-9	hSpCas9	negative selection	10069330
27437291	27437314	2	+	27869803	HPAFII	viability after 31 days	AGAGTCCTCATATGTGCCACAGG	NRBP1	ENSG00000115216	0.678566508483384	[89]	[121,35,NaN]	5	hSpCas9	negative selection	10069331
27439853	27439876	2	-	27869803	HPAFII	viability after 31 days	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-7.366301145161107	[293]	[0,0,NaN]	-9	hSpCas9	negative selection	10069332
27440917	27440940	2	-	27869803	HPAFII	viability after 31 days	TTGCGAGTCTCCACCTCAGCTGG	NRBP1	ENSG00000115216	-0.004962338429546631	[202]	[24,209,NaN]	0	hSpCas9	negative selection	10069333
27441144	27441167	2	+	27869803	HPAFII	viability after 31 days	CAACATTGAGTCGGTGGAGGAGG	NRBP1	ENSG00000115216	0.5623027181320908	[212]	[120,236,NaN]	4	hSpCas9	negative selection	10069334
27433367	27433390	2	-	28162770	P31FUJ	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-1.417226775551806	[99]	[43]	-7	hSpCas9	negative selection	10202490
27434069	27434092	2	+	28162770	P31FUJ	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-1.1456502553192967	[272]	[144]	-7	hSpCas9	negative selection	10202491
27433774	27433797	2	+	28162770	P31FUJ	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	-0.5068610789343088	[288]	[238]	-4	hSpCas9	negative selection	10202492
27437307	27437330	2	-	28162770	P31FUJ	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-4.005391708311306	[204]	[14]	-9	hSpCas9	negative selection	10202493
27439853	27439876	2	-	28162770	P31FUJ	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-5.288084639915568	[132]	[3]	-9	hSpCas9	negative selection	10202494
27439876	27439899	2	-	28162770	P31FUJ	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-1.7174299758782956	[360]	[128]	-8	hSpCas9	negative selection	10202495
27440847	27440870	2	+	28162770	P31FUJ	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.228574009531335	[336]	[463]	2	hSpCas9	negative selection	10202496
27441138	27441161	2	+	28162770	P31FUJ	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-1.544388355080282	[416]	[167]	-7	hSpCas9	negative selection	10202497
27433289	27433312	2	+	28162770	P31FUJ	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.9061736793573001	[857]	[537]	-6	hSpCas9	negative selection	10202498
27433708	27433731	2	+	28162770	P31FUJ	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-3.515736167685877	[145]	[14]	-9	hSpCas9	negative selection	10202499
27433367	27433390	2	-	28162770	TF1	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10371856
27434069	27434092	2	+	28162770	TF1	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10371857
27433774	27433797	2	+	28162770	TF1	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10371858
27437307	27437330	2	-	28162770	TF1	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10371859
27439853	27439876	2	-	28162770	TF1	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10371860
27439876	27439899	2	-	28162770	TF1	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10371861
27440847	27440870	2	+	28162770	TF1	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	NaN	[NaN]	[368]	1	hSpCas9	negative selection	10371862
27441138	27441161	2	+	28162770	TF1	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10371863
27433289	27433312	2	+	28162770	TF1	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	NaN	[NaN]	[388]	1	hSpCas9	negative selection	10371864
27433708	27433731	2	+	28162770	TF1	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10371865
27433367	27433390	2	-	28162770	SKM1	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-2.6964708159381465	[32]	[8]	-9	hSpCas9	negative selection	10541222
27434069	27434092	2	+	28162770	SKM1	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-0.7134772412438363	[63]	[68]	-5	hSpCas9	negative selection	10541223
27433774	27433797	2	+	28162770	SKM1	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	0.20224584822467176	[58]	[119]	2	hSpCas9	negative selection	10541224
27437307	27437330	2	-	28162770	SKM1	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-1.3674358345565243	[53]	[36]	-7	hSpCas9	negative selection	10541225
27439853	27439876	2	-	28162770	SKM1	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.8220016980220056	[38]	[38]	-6	hSpCas9	negative selection	10541226
27439876	27439899	2	-	28162770	SKM1	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-0.9012283891725805	[130]	[123]	-6	hSpCas9	negative selection	10541227
27440847	27440870	2	+	28162770	SKM1	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	-0.33960893094139705	[67]	[94]	-3	hSpCas9	negative selection	10541228
27441138	27441161	2	+	28162770	SKM1	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-0.720122084002792	[81]	[87]	-5	hSpCas9	negative selection	10541229
27433289	27433312	2	+	28162770	SKM1	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.13847536281725992	[164]	[264]	-1	hSpCas9	negative selection	10541230
27433708	27433731	2	+	28162770	SKM1	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-0.7439991860207326	[35]	[37]	-5	hSpCas9	negative selection	10541231
27433367	27433390	2	-	28162770	SKM1	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-2.6964708159381465	[32]	[8]	-9	hSpCas9	negative selection	10710588
27434069	27434092	2	+	28162770	SKM1	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-0.7134772412438363	[63]	[68]	-5	hSpCas9	negative selection	10710589
27433774	27433797	2	+	28162770	SKM1	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	0.20224584822467176	[58]	[119]	2	hSpCas9	negative selection	10710590
27437307	27437330	2	-	28162770	SKM1	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-1.3674358345565243	[53]	[36]	-7	hSpCas9	negative selection	10710591
27439853	27439876	2	-	28162770	SKM1	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.8220016980220056	[38]	[38]	-6	hSpCas9	negative selection	10710592
27439876	27439899	2	-	28162770	SKM1	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-0.9012283891725805	[130]	[123]	-6	hSpCas9	negative selection	10710593
27440847	27440870	2	+	28162770	SKM1	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	-0.33960893094139705	[67]	[94]	-3	hSpCas9	negative selection	10710594
27441138	27441161	2	+	28162770	SKM1	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-0.720122084002792	[81]	[87]	-5	hSpCas9	negative selection	10710595
27433289	27433312	2	+	28162770	SKM1	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.13847536281725992	[164]	[264]	-1	hSpCas9	negative selection	10710596
27433708	27433731	2	+	28162770	SKM1	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-0.7439991860207326	[35]	[37]	-5	hSpCas9	negative selection	10710597
27433367	27433390	2	-	28162770	PL21	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-0.720425918016275	[105]	[27]	-5	hSpCas9	negative selection	10879954
27434069	27434092	2	+	28162770	PL21	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-0.40837761421073293	[246]	[80]	-3	hSpCas9	negative selection	10879955
27433774	27433797	2	+	28162770	PL21	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	0.7107547737503951	[291]	[207]	6	hSpCas9	negative selection	10879956
27437307	27437330	2	-	28162770	PL21	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-0.8313386169838479	[138]	[33]	-5	hSpCas9	negative selection	10879957
27439853	27439876	2	-	28162770	PL21	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-1.9804326311525005	[135]	[14]	-8	hSpCas9	negative selection	10879958
27439876	27439899	2	-	28162770	PL21	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-0.374016131275253	[398]	[133]	-3	hSpCas9	negative selection	10879959
27440847	27440870	2	+	28162770	PL21	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.6883614603721262	[220]	[154]	6	hSpCas9	negative selection	10879960
27441138	27441161	2	+	28162770	PL21	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	0.30416267903254846	[213]	[114]	2	hSpCas9	negative selection	10879961
27433289	27433312	2	+	28162770	PL21	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.4398642497897982	[560]	[179]	-3	hSpCas9	negative selection	10879962
27433708	27433731	2	+	28162770	PL21	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	0.5844803165452476	[94]	[61]	5	hSpCas9	negative selection	10879963
27433367	27433390	2	-	28162770	P31FUJ	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-1.417226775551806	[99]	[43]	-7	hSpCas9	negative selection	11049320
27434069	27434092	2	+	28162770	P31FUJ	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-1.1456502553192967	[272]	[144]	-7	hSpCas9	negative selection	11049321
27433774	27433797	2	+	28162770	P31FUJ	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	-0.5068610789343088	[288]	[238]	-4	hSpCas9	negative selection	11049322
27437307	27437330	2	-	28162770	P31FUJ	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-4.005391708311306	[204]	[14]	-9	hSpCas9	negative selection	11049323
27439853	27439876	2	-	28162770	P31FUJ	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-5.288084639915568	[132]	[3]	-9	hSpCas9	negative selection	11049324
27439876	27439899	2	-	28162770	P31FUJ	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-1.7174299758782956	[360]	[128]	-8	hSpCas9	negative selection	11049325
27440847	27440870	2	+	28162770	P31FUJ	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.228574009531335	[336]	[463]	2	hSpCas9	negative selection	11049326
27441138	27441161	2	+	28162770	P31FUJ	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-1.544388355080282	[416]	[167]	-7	hSpCas9	negative selection	11049327
27433289	27433312	2	+	28162770	P31FUJ	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.9061736793573001	[857]	[537]	-6	hSpCas9	negative selection	11049328
27433708	27433731	2	+	28162770	P31FUJ	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-3.515736167685877	[145]	[14]	-9	hSpCas9	negative selection	11049329
27433367	27433390	2	-	28162770	OCIAML5	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-1.8915949350506343	[36]	[17]	-7	hSpCas9	negative selection	11218686
27434069	27434092	2	+	28162770	OCIAML5	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-1.1067857084857873	[172]	[144]	-6	hSpCas9	negative selection	11218687
27433774	27433797	2	+	28162770	OCIAML5	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	-0.6582433017243201	[152]	[174]	-4	hSpCas9	negative selection	11218688
27437307	27437330	2	-	28162770	OCIAML5	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-6.437029071585153	[47]	[0]	-9	hSpCas9	negative selection	11218689
27439853	27439876	2	-	28162770	OCIAML5	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-3.0219915723063098	[71]	[15]	-8	hSpCas9	negative selection	11218690
27439876	27439899	2	-	28162770	OCIAML5	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-1.0205201850896413	[244]	[217]	-6	hSpCas9	negative selection	11218691
27440847	27440870	2	+	28162770	OCIAML5	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.638098175312908	[151]	[426]	5	hSpCas9	negative selection	11218692
27441138	27441161	2	+	28162770	OCIAML5	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-0.7341032335097073	[222]	[241]	-5	hSpCas9	negative selection	11218693
27433289	27433312	2	+	28162770	OCIAML5	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.43047135556299065	[438]	[587]	-3	hSpCas9	negative selection	11218694
27433708	27433731	2	+	28162770	OCIAML5	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-0.77806598942022	[56]	[59]	-5	hSpCas9	negative selection	11218695
27433367	27433390	2	-	28162770	EOL1	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-2.4986636591540092	[235]	[21]	-8	hSpCas9	negative selection	11388052
27434069	27434092	2	+	28162770	EOL1	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	0.6334989895671441	[311]	[254]	5	hSpCas9	negative selection	11388053
27433774	27433797	2	+	28162770	EOL1	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	0.8041012825584081	[411]	[378]	7	hSpCas9	negative selection	11388054
27437307	27437330	2	-	28162770	EOL1	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-0.9132795027113397	[310]	[86]	-6	hSpCas9	negative selection	11388055
27439853	27439876	2	-	28162770	EOL1	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-1.1458415563208633	[251]	[59]	-6	hSpCas9	negative selection	11388056
27439876	27439899	2	-	28162770	EOL1	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	0.17297409048217682	[760]	[451]	1	hSpCas9	negative selection	11388057
27440847	27440870	2	+	28162770	EOL1	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.15157164163862824	[310]	[181]	1	hSpCas9	negative selection	11388058
27441138	27441161	2	+	28162770	EOL1	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-0.11085756456066434	[329]	[160]	-1	hSpCas9	negative selection	11388059
27433289	27433312	2	+	28162770	EOL1	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	0.4614630978845822	[691]	[501]	4	hSpCas9	negative selection	11388060
27433708	27433731	2	+	28162770	EOL1	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-0.2576555596502146	[117]	[51]	-2	hSpCas9	negative selection	11388061
27433367	27433390	2	-	28162770	MOLM13	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-6.101966226786369	[189]	[1]	-9	hSpCas9	negative selection	11557418
27434069	27434092	2	+	28162770	MOLM13	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-1.5159909530921443	[355]	[89]	-6	hSpCas9	negative selection	11557419
27433774	27433797	2	+	28162770	MOLM13	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	0.6166247611557175	[441]	[489]	4	hSpCas9	negative selection	11557420
27437307	27437330	2	-	28162770	MOLM13	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-2.359929643072741	[283]	[39]	-8	hSpCas9	negative selection	11557421
27439853	27439876	2	-	28162770	MOLM13	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-2.578123016212257	[222]	[26]	-8	hSpCas9	negative selection	11557422
27439876	27439899	2	-	28162770	MOLM13	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	1.1277818447524441	[568]	[898]	8	hSpCas9	negative selection	11557423
27440847	27440870	2	+	28162770	MOLM13	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.11814334251745416	[287]	[225]	0	hSpCas9	negative selection	11557424
27441138	27441161	2	+	28162770	MOLM13	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-1.8148035500596833	[398]	[81]	-7	hSpCas9	negative selection	11557425
27433289	27433312	2	+	28162770	MOLM13	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.36155048821531466	[756]	[425]	-2	hSpCas9	negative selection	11557426
27433708	27433731	2	+	28162770	MOLM13	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-1.7493413346760902	[185]	[39]	-7	hSpCas9	negative selection	11557427
27433367	27433390	2	-	28162770	HEL	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-2.6621157495280636	[167]	[16]	-8	hSpCas9	negative selection	11726784
27434069	27434092	2	+	28162770	HEL	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-0.5155981951667437	[278]	[124]	-3	hSpCas9	negative selection	11726785
27433774	27433797	2	+	28162770	HEL	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	0.16170377394727303	[327]	[234]	1	hSpCas9	negative selection	11726786
27437307	27437330	2	-	28162770	HEL	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-0.9144786782378951	[205]	[69]	-5	hSpCas9	negative selection	11726787
27439853	27439876	2	-	28162770	HEL	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-2.4837935739285752	[130]	[14]	-8	hSpCas9	negative selection	11726788
27439876	27439899	2	-	28162770	HEL	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-1.3864528807144259	[648]	[158]	-7	hSpCas9	negative selection	11726789
27440847	27440870	2	+	28162770	HEL	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.8380630101386343	[268]	[307]	7	hSpCas9	negative selection	11726790
27441138	27441161	2	+	28162770	HEL	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-0.35337773351241486	[370]	[185]	-2	hSpCas9	negative selection	11726791
27433289	27433312	2	+	28162770	HEL	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	0.0034652114013766777	[608]	[390]	0	hSpCas9	negative selection	11726792
27433708	27433731	2	+	28162770	HEL	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-3.794666480306941	[129]	[5]	-9	hSpCas9	negative selection	11726793
27433367	27433390	2	-	28162770	MV411	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-4.935784273272995	[108]	[2]	-9	hSpCas9	negative selection	11896150
27434069	27434092	2	+	28162770	MV411	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-0.17765361315999137	[191]	[142]	-1	hSpCas9	negative selection	11896151
27433774	27433797	2	+	28162770	MV411	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	0.6407799789623	[200]	[263]	6	hSpCas9	negative selection	11896152
27437307	27437330	2	-	28162770	MV411	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-1.951342313331722	[201]	[43]	-8	hSpCas9	negative selection	11896153
27439853	27439876	2	-	28162770	MV411	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-1.5920977770239788	[135]	[37]	-7	hSpCas9	negative selection	11896154
27439876	27439899	2	-	28162770	MV411	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-0.25627462941521606	[396]	[279]	-2	hSpCas9	negative selection	11896155
27440847	27440870	2	+	28162770	MV411	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.18214609053105624	[225]	[215]	1	hSpCas9	negative selection	11896156
27441138	27441161	2	+	28162770	MV411	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-0.8233837864069216	[333]	[158]	-5	hSpCas9	negative selection	11896157
27433289	27433312	2	+	28162770	MV411	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.15803123964729004	[550]	[415]	-1	hSpCas9	negative selection	11896158
27433708	27433731	2	+	28162770	MV411	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-0.5735923081719054	[105]	[59]	-4	hSpCas9	negative selection	11896159
27433367	27433390	2	-	28162770	MONOMAC1	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-2.1039274426680725	[89]	[23]	-9	hSpCas9	negative selection	12065516
27434069	27434092	2	+	28162770	MONOMAC1	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-0.4841349577838169	[132]	[108]	-4	hSpCas9	negative selection	12065517
27433774	27433797	2	+	28162770	MONOMAC1	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	-0.6547186837468912	[205]	[149]	-5	hSpCas9	negative selection	12065518
27437307	27437330	2	-	28162770	MONOMAC1	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-1.8408930368342784	[124]	[39]	-8	hSpCas9	negative selection	12065519
27439853	27439876	2	-	28162770	MONOMAC1	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.6276712013894161	[92]	[68]	-5	hSpCas9	negative selection	12065520
27439876	27439899	2	-	28162770	MONOMAC1	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-0.8626178079889943	[229]	[144]	-6	hSpCas9	negative selection	12065521
27440847	27440870	2	+	28162770	MONOMAC1	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	-0.15003936752238406	[150]	[155]	-1	hSpCas9	negative selection	12065522
27441138	27441161	2	+	28162770	MONOMAC1	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-1.179758855627718	[165]	[83]	-7	hSpCas9	negative selection	12065523
27433289	27433312	2	+	28162770	MONOMAC1	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	-0.23608962362332853	[336]	[327]	-2	hSpCas9	negative selection	12065524
27433708	27433731	2	+	28162770	MONOMAC1	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	1.2857452588551244	[77]	[217]	9	hSpCas9	negative selection	12065525
27433367	27433390	2	-	28162770	OCIAML2	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-4.570165498793076	[29]	[6]	-9	hSpCas9	negative selection	12234882
27434069	27434092	2	+	28162770	OCIAML2	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	0.18690130142964012	[41]	[264]	1	hSpCas9	negative selection	12234883
27433774	27433797	2	+	28162770	OCIAML2	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	-0.12533773728928826	[48]	[248]	-1	hSpCas9	negative selection	12234884
27437307	27437330	2	-	28162770	OCIAML2	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-2.305570578971665	[32]	[36]	-8	hSpCas9	negative selection	12234885
27439853	27439876	2	-	28162770	OCIAML2	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-0.8629472480209216	[20]	[63]	-6	hSpCas9	negative selection	12234886
27439876	27439899	2	-	28162770	OCIAML2	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	0.23956885936125927	[67]	[444]	2	hSpCas9	negative selection	12234887
27440847	27440870	2	+	28162770	OCIAML2	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.5882638638114073	[38]	[324]	6	hSpCas9	negative selection	12234888
27441138	27441161	2	+	28162770	OCIAML2	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-0.863972253421686	[43]	[133]	-6	hSpCas9	negative selection	12234889
27433289	27433312	2	+	28162770	OCIAML2	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	0.1658088929700805	[77]	[484]	1	hSpCas9	negative selection	12234890
27433708	27433731	2	+	28162770	OCIAML2	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-1.7221685922381254	[24]	[41]	-8	hSpCas9	negative selection	12234891
27433367	27433390	2	-	28162770	OCIAML3	viability	GAGGTTGTGGAGGTCACAGGAGG	NRBP1	ENSG00000115216	-1.8097363313796002	[35]	[30]	-8	hSpCas9	negative selection	12404248
27434069	27434092	2	+	28162770	OCIAML3	viability	CATTAAAGAGAACAAGGCCAGGG	NRBP1	ENSG00000115216	-0.7606575097336145	[54]	[97]	-5	hSpCas9	negative selection	12404249
27433774	27433797	2	+	28162770	OCIAML3	viability	CAAGAACTACAAGCTGCAGGAGG	NRBP1	ENSG00000115216	0.5398481064106275	[71]	[315]	5	hSpCas9	negative selection	12404250
27437307	27437330	2	-	28162770	OCIAML3	viability	GCACTGCTGATGGCTTCCTGTGG	NRBP1	ENSG00000115216	-1.7600175917630927	[45]	[40]	-8	hSpCas9	negative selection	12404251
27439853	27439876	2	-	28162770	OCIAML3	viability	GCCGCAAGGAGTTTGAGCGAGGG	NRBP1	ENSG00000115216	-1.9830499310700624	[54]	[41]	-8	hSpCas9	negative selection	12404252
27439876	27439899	2	-	28162770	OCIAML3	viability	GTTGGTGTCCCACAATGCAGTGG	NRBP1	ENSG00000115216	-0.12007645199175088	[98]	[274]	-1	hSpCas9	negative selection	12404253
27440847	27440870	2	+	28162770	OCIAML3	viability	CCAGCAGCCACAGCAGGAGGAGG	NRBP1	ENSG00000115216	0.6881941762475882	[80]	[393]	6	hSpCas9	negative selection	12404254
27441138	27441161	2	+	28162770	OCIAML3	viability	GCAGTGCAACATTGAGTCGGTGG	NRBP1	ENSG00000115216	-0.7489823003005043	[107]	[193]	-5	hSpCas9	negative selection	12404255
27433289	27433312	2	+	28162770	OCIAML3	viability	TCCCAGACAGTACTTAGCAGTGG	NRBP1	ENSG00000115216	0.34923070981521387	[161]	[622]	3	hSpCas9	negative selection	12404256
27433708	27433731	2	+	28162770	OCIAML3	viability	ATACCTGGCCATGGATACAGAGG	NRBP1	ENSG00000115216	-0.24037068570946263	[26]	[68]	-2	hSpCas9	negative selection	12404257