Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4924
• Symbol:NUCB1
• Description:nucleobindin 1

DataSource: http://genomecrispr.dkfz.de/#!/results/NUCB1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
48904424	48904447	19	+	26472758	Jiyoye	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	1.0562682196467452	[87]	[137]	7	hSpCas9	negative selection	112167
48919059	48919082	19	+	26472758	Jiyoye	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	-0.18435977313876903	[109]	[72]	-1	hSpCas9	negative selection	112168
48919256	48919279	19	+	26472758	Jiyoye	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	-2.177787119215283	[23]	[3]	-8	hSpCas9	negative selection	112169
48921162	48921185	19	+	26472758	Jiyoye	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	-0.005085033102396552	[172]	[129]	0	hSpCas9	negative selection	112170
48904361	48904384	19	+	26472758	Jiyoye	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.22828459880601204	[342]	[302]	1	hSpCas9	negative selection	112171
48904373	48904396	19	-	26472758	Jiyoye	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.23069865025372538	[360]	[231]	-2	hSpCas9	negative selection	112172
48905809	48905832	19	+	26472758	Jiyoye	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	-0.6976208085057364	[156]	[72]	-5	hSpCas9	negative selection	112173
48919041	48919064	19	+	26472758	Jiyoye	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	-1.647272402516503	[53]	[12]	-8	hSpCas9	negative selection	112174
48904424	48904447	19	+	26472758	KBM7	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	0.17823380895963478	[634,468]	[288,291]	1	hSpCas9	negative selection	303285
48919059	48919082	19	+	26472758	KBM7	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	0.13288315598852501	[497,548]	[214,323]	1	hSpCas9	negative selection	303286
48919256	48919279	19	+	26472758	KBM7	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	-0.34690196545550744	[42,39]	[17,12]	-3	hSpCas9	negative selection	303287
48921162	48921185	19	+	26472758	KBM7	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	0.7038399309309815	[632,521]	[513,373]	7	hSpCas9	negative selection	303288
48904361	48904384	19	+	26472758	KBM7	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.23242377167185846	[1374,847]	[647,560]	2	hSpCas9	negative selection	303289
48904373	48904396	19	-	26472758	KBM7	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	0.43526692965137914	[885,1023]	[574,649]	5	hSpCas9	negative selection	303290
48905809	48905832	19	+	26472758	KBM7	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	1.3520503023589927	[350,373]	[322,541]	9	hSpCas9	negative selection	303291
48919041	48919064	19	+	26472758	KBM7	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	-0.21909421500606685	[102,85]	[18,54]	-2	hSpCas9	negative selection	303292
48904424	48904447	19	+	26472758	Raji	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	0.10738353537359957	[283]	[70]	1	hSpCas9	negative selection	494403
48919059	48919082	19	+	26472758	Raji	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	-0.13680480956419297	[288]	[60]	-1	hSpCas9	negative selection	494404
48919256	48919279	19	+	26472758	Raji	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	-2.1405439780699864	[18]	[0]	-8	hSpCas9	negative selection	494405
48921162	48921185	19	+	26472758	Raji	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	0.7903542398990764	[146]	[58]	7	hSpCas9	negative selection	494406
48904361	48904384	19	+	26472758	Raji	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.37309207550571877	[538]	[161]	3	hSpCas9	negative selection	494407
48904373	48904396	19	-	26472758	Raji	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	0.8170417835440703	[383]	[156]	7	hSpCas9	negative selection	494408
48905809	48905832	19	+	26472758	Raji	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	0.10018803396939557	[200]	[49]	0	hSpCas9	negative selection	494409
48919041	48919064	19	+	26472758	Raji	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	-1.593056182767493	[25]	[1]	-8	hSpCas9	negative selection	494410
48904424	48904447	19	+	26472758	K562	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	-0.06102124443234662	[434]	[351]	0	hSpCas9	negative selection	685521
48919059	48919082	19	+	26472758	K562	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	0.5774406524373941	[284]	[358]	5	hSpCas9	negative selection	685522
48919256	48919279	19	+	26472758	K562	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	2.1289415102465115	[12]	[47]	9	hSpCas9	negative selection	685523
48921162	48921185	19	+	26472758	K562	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	-0.5200931933854219	[422]	[248]	-3	hSpCas9	negative selection	685524
48904361	48904384	19	+	26472758	K562	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.3045397201040174	[798]	[832]	2	hSpCas9	negative selection	685525
48904373	48904396	19	-	26472758	K562	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.07551806940182393	[723]	[579]	0	hSpCas9	negative selection	685526
48905809	48905832	19	+	26472758	K562	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	0.8350013953739037	[426]	[642]	7	hSpCas9	negative selection	685527
48919041	48919064	19	+	26472758	K562	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	-0.052563010090684426	[42]	[34]	0	hSpCas9	negative selection	685528
48900913	48900936	19	-	26627737	DLD1	viability	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.5385360982920724	[624]	[308,273,269]	5	hSpCas9	negative selection	806014
48905857	48905880	19	+	26627737	DLD1	viability	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.09849424553903197	[249]	[127,25,92]	1	hSpCas9	negative selection	806015
48919065	48919088	19	+	26627737	DLD1	viability	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	-0.6363915204613704	[380]	[77,151,12]	-6	hSpCas9	negative selection	806016
48900913	48900936	19	-	26627737	GBM cells	viability after 5 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.27301174265954864	[276]	[189,168]	4	hSpCas9	negative selection	888329
48905857	48905880	19	+	26627737	GBM cells	viability after 5 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.19914689867372903	[133]	[65,98]	3	hSpCas9	negative selection	888330
48919065	48919088	19	+	26627737	GBM cells	viability after 5 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	0.3342509357750603	[246]	[197,135]	5	hSpCas9	negative selection	888331
48900913	48900936	19	-	26627737	GBM cells	viability after 13 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	-0.02254410148920577	[276]	[217,90]	0	hSpCas9	negative selection	970644
48905857	48905880	19	+	26627737	GBM cells	viability after 13 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.5486303069877418	[133]	[107,104]	6	hSpCas9	negative selection	970645
48919065	48919088	19	+	26627737	GBM cells	viability after 13 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	0.22422914246730286	[246]	[230,95]	3	hSpCas9	negative selection	970646
48900913	48900936	19	-	26627737	GBM cells	viability after 21 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.03930232931014127	[276]	[162,146]	0	hSpCas9	negative selection	1052959
48905857	48905880	19	+	26627737	GBM cells	viability after 21 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.7030226255112054	[133]	[129,107]	7	hSpCas9	negative selection	1052960
48919065	48919088	19	+	26627737	GBM cells	viability after 21 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	0.35149858936216477	[246]	[177,164]	3	hSpCas9	negative selection	1052961
48900913	48900936	19	-	26627737	RPE1	viability after 9 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	3.8118229280284233	[140]	[515,753]	9	hSpCas9	negative selection	1135274
48905857	48905880	19	+	26627737	RPE1	viability after 9 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.7014639163193332	[588]	[167,469]	4	hSpCas9	negative selection	1135275
48919065	48919088	19	+	26627737	RPE1	viability after 9 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	-1.1043365386982398	[445]	[67,60]	-7	hSpCas9	negative selection	1135276
48900913	48900936	19	-	26627737	RPE1	viability after 12 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	3.7505093232657627	[140]	[487,532]	9	hSpCas9	negative selection	1217589
48905857	48905880	19	+	26627737	RPE1	viability after 12 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.22403156831181645	[588]	[178,190]	1	hSpCas9	negative selection	1217590
48919065	48919088	19	+	26627737	RPE1	viability after 12 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	-0.843629486409308	[445]	[41,92]	-5	hSpCas9	negative selection	1217591
48900913	48900936	19	-	26627737	RPE1	viability after 15 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	4.420308891130547	[140]	[768,935]	9	hSpCas9	negative selection	1299904
48905857	48905880	19	+	26627737	RPE1	viability after 15 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	-0.24052269130341236	[588]	[54,223]	-1	hSpCas9	negative selection	1299905
48919065	48919088	19	+	26627737	RPE1	viability after 15 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	-1.406206501260177	[445]	[69,25]	-7	hSpCas9	negative selection	1299906
48900913	48900936	19	-	26627737	RPE1	viability after 18 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	4.484409160405565	[140]	[829,874]	9	hSpCas9	negative selection	1382219
48905857	48905880	19	+	26627737	RPE1	viability after 18 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.5720694445703918	[588]	[186,288]	3	hSpCas9	negative selection	1382220
48919065	48919088	19	+	26627737	RPE1	viability after 18 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	-0.8573379195935716	[445]	[49,83]	-5	hSpCas9	negative selection	1382221
48900913	48900936	19	-	26627737	HeLa	viability after 8 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.894500834805907	[231]	[184,242,137]	7	hSpCas9	negative selection	1464534
48905857	48905880	19	+	26627737	HeLa	viability after 8 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	-0.9418270928250208	[296]	[146,43,30]	-7	hSpCas9	negative selection	1464535
48919065	48919088	19	+	26627737	HeLa	viability after 8 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	0.8854130054606247	[280]	[221,261,194]	7	hSpCas9	negative selection	1464536
48900913	48900936	19	-	26627737	HeLa	viability after 12 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	1.1445393669765587	[231]	[151,335,132]	7	hSpCas9	negative selection	1546849
48905857	48905880	19	+	26627737	HeLa	viability after 12 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.3360263964843722	[296]	[174,82,214]	3	hSpCas9	negative selection	1546850
48919065	48919088	19	+	26627737	HeLa	viability after 12 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	1.096069478923108	[280]	[321,199,229]	7	hSpCas9	negative selection	1546851
48900913	48900936	19	-	26627737	HeLa	viability after 15 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	1.3125699912705502	[231]	[208,285,206]	8	hSpCas9	negative selection	1629164
48905857	48905880	19	+	26627737	HeLa	viability after 15 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	-0.638200703330347	[296]	[58,63,112]	-5	hSpCas9	negative selection	1629165
48919065	48919088	19	+	26627737	HeLa	viability after 15 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	1.0970736601965092	[280]	[86,454,189]	7	hSpCas9	negative selection	1629166
48900913	48900936	19	-	26627737	HeLa	viability after 18 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	1.3693441792861776	[231]	[151,244,206]	8	hSpCas9	negative selection	1711479
48905857	48905880	19	+	26627737	HeLa	viability after 18 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	-0.6689044085658811	[296]	[37,50,112]	-5	hSpCas9	negative selection	1711480
48919065	48919088	19	+	26627737	HeLa	viability after 18 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	1.1182080769899498	[280]	[57,385,189]	7	hSpCas9	negative selection	1711481
48900913	48900936	19	-	26627737	HCT116	viability after 6 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	1.413019759502007	[596]	[305,218]	7	hSpCas9	negative selection	1793794
48905857	48905880	19	+	26627737	HCT116	viability after 6 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	1.7636942830361853	[266]	[157,133]	8	hSpCas9	negative selection	1793795
48919065	48919088	19	+	26627737	HCT116	viability after 6 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	0.642241244870429	[786]	[263,153]	3	hSpCas9	negative selection	1793796
48900913	48900936	19	-	26627737	HCT116	viability after 8 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.45259895881628515	[313]	[240,197,270]	5	hSpCas9	negative selection	1876109
48905857	48905880	19	+	26627737	HCT116	viability after 8 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	-0.7255837409658827	[236]	[73,96,65]	-7	hSpCas9	negative selection	1876110
48919065	48919088	19	+	26627737	HCT116	viability after 8 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	0.6964696223829946	[207]	[159,231,164]	6	hSpCas9	negative selection	1876111
48900913	48900936	19	-	26627737	HCT116	viability after 9 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.2525056295960808	[596]	[166,207]	2	hSpCas9	negative selection	1958424
48905857	48905880	19	+	26627737	HCT116	viability after 9 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	1.3185662055439984	[266]	[107,232]	8	hSpCas9	negative selection	1958425
48919065	48919088	19	+	26627737	HCT116	viability after 9 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	-0.47467501503229637	[786]	[253,69]	-3	hSpCas9	negative selection	1958426
48900913	48900936	19	-	26627737	HCT116	viability after 12 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.7810027982946192	[313]	[292,290,265]	7	hSpCas9	negative selection	2040739
48905857	48905880	19	+	26627737	HCT116	viability after 12 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	-1.5413431523674563	[236]	[65,28,30]	-9	hSpCas9	negative selection	2040740
48919065	48919088	19	+	26627737	HCT116	viability after 12 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	0.34888005420800816	[207]	[154,169,91]	3	hSpCas9	negative selection	2040741
48900913	48900936	19	-	26627737	HCT116	viability after 15 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.356002572813105	[313]	[235,223,232]	3	hSpCas9	negative selection	2123054
48905857	48905880	19	+	26627737	HCT116	viability after 15 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.11362013983356076	[236]	[181,198,65]	1	hSpCas9	negative selection	2123055
48919065	48919088	19	+	26627737	HCT116	viability after 15 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	0.8857555112463884	[207]	[224,160,275]	7	hSpCas9	negative selection	2123056
48900913	48900936	19	-	26627737	HCT116	viability after 18 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.621269856181702	[313]	[246,163,296]	5	hSpCas9	negative selection	2205369
48905857	48905880	19	+	26627737	HCT116	viability after 18 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.16522871947803536	[236]	[220,119,40]	1	hSpCas9	negative selection	2205370
48919065	48919088	19	+	26627737	HCT116	viability after 18 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	0.4760220238987636	[207]	[157,128,132]	4	hSpCas9	negative selection	2205371
48922089	48922112	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTCTGAGGGAGGAGGGGCTGGG	NUCB1	ENSG00000104805	0.375444922081557	[26,26]	[1,13]	1	dCas9-VP64	positive selection	2447325
48922089	48922112	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTCTGAGGGAGGAGGGGCTGGG	NUCB1	ENSG00000104805	1.9568523660448214	[60,97]	[51,146]	8	dCas9-VP64	positive selection	2542580
48904362	48904385	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.22384584776409366	[0,0]	[0,0]	5	hSpCas9	positive selection	3006803
48904373	48904396	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	0.3488820199841936	[3,3]	[3,4]	7	hSpCas9	positive selection	3006804
48904362	48904385	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.4833744715089985	[0,0]	[0,0]	8	hSpCas9	positive selection	3074661
48904373	48904396	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.31477993971633056	[3,3]	[2,1]	-5	hSpCas9	positive selection	3074662
48904435	48904458		-	24336571	A375	resistance to PLX after 7 days	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	0.32004618352365344	[22,23]	[28,28]	8	hSpCas9	positive selection	3131893
48922326	48922349		-	24336571	A375	resistance to PLX after 7 days	TCACCGGCTGGAGCTGGGACAGG	NUCB1	ENSG00000104805	0.0025359969782732805	[8,9]	[9,8]	0	hSpCas9	positive selection	3131894
48922412	48922435		-	24336571	A375	resistance to PLX after 7 days	TCCCGGAGGATCACAGATGCTGG	NUCB1	ENSG00000104805	-0.38828979956746623	[9,7]	[4,7]	-9	hSpCas9	positive selection	3131895
48904433	48904456		+	24336571	A375	resistance to PLX after 7 days	TGCCAATGCGGAGGACATCAAGG	NUCB1	ENSG00000104805	0.20071032594527916	[29,23]	[30,30]	6	hSpCas9	positive selection	3131896
48904435	48904458		-	24336571	A375	resistance to PLX after 14 days	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	0.35056476874846754	[27,23]	[15,14]	3	hSpCas9	positive selection	3189686
48922326	48922349		-	24336571	A375	resistance to PLX after 14 days	TCACCGGCTGGAGCTGGGACAGG	NUCB1	ENSG00000104805	0.3218135540651876	[4,9]	[3,4]	3	hSpCas9	positive selection	3189687
48922412	48922435		-	24336571	A375	resistance to PLX after 14 days	TCCCGGAGGATCACAGATGCTGG	NUCB1	ENSG00000104805	-0.38507263540228387	[7,8]	[2,2]	-4	hSpCas9	positive selection	3189688
48904433	48904456		+	24336571	A375	resistance to PLX after 14 days	TGCCAATGCGGAGGACATCAAGG	NUCB1	ENSG00000104805	-0.18453302699572482	[30,31]	[10,13]	-2	hSpCas9	positive selection	3189689
48904435	48904458		-	24336571	A375	viability after 7 days	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.15105127853386557	[27]	[22,23]	-2	hSpCas9	negative selection	3247479
48922326	48922349		-	24336571	A375	viability after 7 days	TCACCGGCTGGAGCTGGGACAGG	NUCB1	ENSG00000104805	0.25950050256338514	[7]	[8,9]	4	hSpCas9	negative selection	3247480
48922412	48922435		-	24336571	A375	viability after 7 days	TCCCGGAGGATCACAGATGCTGG	NUCB1	ENSG00000104805	0.15934186439222608	[7]	[9,7]	2	hSpCas9	negative selection	3247481
48904433	48904456		+	24336571	A375	viability after 7 days	TGCCAATGCGGAGGACATCAAGG	NUCB1	ENSG00000104805	0.29096999992253003	[22]	[29,23]	4	hSpCas9	negative selection	3247482
48904435	48904458		-	24336571	A375	viability after 14 days	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.002500480003474359	[27]	[27,23]	0	hSpCas9	negative selection	3305272
48922326	48922349		-	24336571	A375	viability after 14 days	TCACCGGCTGGAGCTGGGACAGG	NUCB1	ENSG00000104805	-0.005146650749617843	[7]	[4,9]	0	hSpCas9	negative selection	3305273
48922412	48922435		-	24336571	A375	viability after 14 days	TCCCGGAGGATCACAGATGCTGG	NUCB1	ENSG00000104805	0.13238951461183768	[7]	[7,8]	1	hSpCas9	negative selection	3305274
48904433	48904456		+	24336571	A375	viability after 14 days	TGCCAATGCGGAGGACATCAAGG	NUCB1	ENSG00000104805	0.5242375599898775	[22]	[30,31]	6	hSpCas9	negative selection	3305275
48904435	48904458	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.664514725628655	[484,484]	[1,1]	-4	hSpCas9	positive selection	3382598
48905788	48905811	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.30312990105895976	[123,123]	[0,0]	1	hSpCas9	positive selection	3382599
48904376	48904399	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	7.890430206658337	[667,667]	[1035,1035]	9	hSpCas9	positive selection	3382600
48904361	48904384	19	+	26780180	HT29	viability (Avana library 4 designs)	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0	[]	[]	0	hSpCas9	negative selection	3444700
48904373	48904396	19	-	26780180	HT29	viability (Avana library 4 designs)	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	1.65508717330184	[]	[]	6	hSpCas9	negative selection	3444701
48904373	48904396	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	2.21230712739488	[]	[]	3	hSpCas9	negative selection	3537056
48904361	48904384	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	-0.0782513817268516	[]	[]	0	hSpCas9	negative selection	3537057
48905809	48905832	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	1.71005831334121	[]	[]	2	hSpCas9	negative selection	3537058
48904382	48904405	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCATCGATGTACTGGAGACGG	NUCB1	ENSG00000104805	2.04291042049744	[]	[]	3	hSpCas9	negative selection	3537059
48904373	48904396	19	-	26780180	A375	viability (Avana lentiGuide)	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	1.59843296287944	[]	[]	1	hSpCas9	negative selection	3645715
48904361	48904384	19	+	26780180	A375	viability (Avana lentiGuide)	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0	[]	[]	0	hSpCas9	negative selection	3645716
48905809	48905832	19	+	26780180	A375	viability (Avana lentiGuide)	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	-2.70955508875693	[]	[]	-5	hSpCas9	negative selection	3645717
48904382	48904405	19	+	26780180	A375	viability (Avana lentiGuide)	GGTCATCGATGTACTGGAGACGG	NUCB1	ENSG00000104805	6.65979732338692	[]	[]	5	hSpCas9	negative selection	3645718
48904373	48904396	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.08582083159388965	[5]	[4,4]	-1	hSpCas9	positive selection	3754374
48904361	48904384	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	-0.07833589988046508	[0]	[0,0]	-1	hSpCas9	positive selection	3754375
48905809	48905832	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	0.014491608912467369	[4]	[4,3]	0	hSpCas9	positive selection	3754376
48904382	48904405	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCATCGATGTACTGGAGACGG	NUCB1	ENSG00000104805	-0.03411326207427615	[5]	[5,4]	0	hSpCas9	positive selection	3754377
48904373	48904396	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.28750693211215517	[5]	[2,4]	-4	hSpCas9	positive selection	3862981
48904361	48904384	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.24644513604583196	[0]	[0,0]	6	hSpCas9	positive selection	3862982
48905809	48905832	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	-0.10904082191652434	[4]	[2,4]	-1	hSpCas9	positive selection	3862983
48904382	48904405	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCATCGATGTACTGGAGACGG	NUCB1	ENSG00000104805	0.1264219695585617	[5]	[5,4]	3	hSpCas9	positive selection	3862984
48904435	48904458	19	-	26780180	A375	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	1.68526215877166	[]	[]	9	hSpCas9	negative selection	3974176
48905788	48905811	19	+	26780180	A375	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	1.59216896657015	[]	[]	8	hSpCas9	negative selection	3974177
48904376	48904399	19	-	26780180	A375	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.883062276966208	[]	[]	3	hSpCas9	negative selection	3974178
48905817	48905840	19	+	26780180	A375	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.312808043024141	[]	[]	0	hSpCas9	negative selection	3974179
48904435	48904458	19	-	26780180	HT29	viability (GeCKOv2 library)	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	0.754070478259123	[]	[]	3	hSpCas9	negative selection	4082142
48905788	48905811	19	+	26780180	HT29	viability (GeCKOv2 library)	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	1.28781349006343	[]	[]	6	hSpCas9	negative selection	4082143
48904376	48904399	19	-	26780180	HT29	viability (GeCKOv2 library)	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.664364177819036	[]	[]	2	hSpCas9	negative selection	4082144
48905817	48905840	19	+	26780180	HT29	viability (GeCKOv2 library)	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.337386945011121	[]	[]	0	hSpCas9	negative selection	4082145
48904435	48904458	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	0.2688740654801416	[4]	[3,3]	6	hSpCas9	positive selection	4156628
48922326	48922349	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCACCGGCTGGAGCTGGGACAGG	NUCB1	ENSG00000104805	-0.13176050327271366	[3]	[1,1]	-3	hSpCas9	positive selection	4156629
48922412	48922435	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCGGAGGATCACAGATGCTGG	NUCB1	ENSG00000104805	-0.22454238336079446	[3]	[2,1]	-5	hSpCas9	positive selection	4156630
48904433	48904456	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCCAATGCGGAGGACATCAAGG	NUCB1	ENSG00000104805	-0.026127418334218777	[4]	[2,3]	0	hSpCas9	positive selection	4156631
48904435	48904458	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	0.7145791466105176	[4]	[3,1,1,3]	4	hSpCas9	positive selection	4220650
48922326	48922349	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCACCGGCTGGAGCTGGGACAGG	NUCB1	ENSG00000104805	-0.2331784765857614	[2]	[0,0,0,0]	-3	hSpCas9	positive selection	4220651
48922412	48922435	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCGGAGGATCACAGATGCTGG	NUCB1	ENSG00000104805	-0.04773891398950747	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4220652
48904433	48904456	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCCAATGCGGAGGACATCAAGG	NUCB1	ENSG00000104805	0.18649664880579692	[4]	[2,2,3,0]	1	hSpCas9	positive selection	4220653
48905817	48905840	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	-0.10816135294133089	[1]	[1,0]	-2	hSpCas9	positive selection	4286566
48904435	48904458	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.026107593165236254	[4]	[3,3]	0	hSpCas9	positive selection	4350822
48905788	48905811	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.08699818911454746	[2]	[2,1]	1	hSpCas9	positive selection	4350823
48904376	48904399	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.011028046833783278	[4]	[3,3]	0	hSpCas9	positive selection	4350824
48900912	48900934	19	-	27760321	OCIAML3	viability	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.6224923933921793	[727,579]	[714,870]	7	hSpCas9	negative selection	4423872
48900912	48900934	19	-	27760321	OCIAML2	viability	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.5695396135959523	[727,579]	[653,946]	7	hSpCas9	negative selection	4507335
48900912	48900934	19	-	27760321	MV411	viability	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.6296322794788118	[727,579]	[556,823]	4	hSpCas9	negative selection	4590798
48900912	48900934	19	-	27760321	HL60	viability	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.4944621147216144	[727,579]	[668,831]	6	hSpCas9	negative selection	4674261
48900912	48900934	19	-	27760321	HT1080	viability	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.4966820789479769	[579,452]	[212,374]	2	hSpCas9	negative selection	4757724
48900912	48900934	19	-	27760321	HT29	viability after 7 days	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.18371885806707333	[579,452]	[1285,659,402]	3	hSpCas9	negative selection	4841187
48900912	48900934	19	-	27760321	HT29	viability after 25 days	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.02939108000932822	[579,452]	[684,575,532]	0	hSpCas9	negative selection	4924650
48900912	48900934	19	-	27760321	HT29	viability after 22 days	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.19361314962751364	[579,452]	[742,726,575]	2	hSpCas9	negative selection	5008113
48900912	48900934	19	-	27760321	HT29	viability after 19 days	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.3367392007162612	[579,452]	[800,766,677]	3	hSpCas9	negative selection	5091576
48900912	48900934	19	-	27760321	HT29	viability after 16 days	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.04198685270106983	[579,452]	[544,749,480]	0	hSpCas9	negative selection	5175039
48900912	48900934	19	-	27760321	HT29	viability after 13 days	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.6437475297339421	[579,452]	[1061,1181,585]	8	hSpCas9	negative selection	5258502
48900912	48900934	19	-	27760321	HT29	viability after 10 days	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.3116173114970897	[579,452]	[827,766,804]	4	hSpCas9	negative selection	5341965
48900912	48900934	19	-	27760321	MOLM13	viability	ACGGGACTCTCAGTCGCAGGGG	NUCB1	ENSG00000104805	0.05675525149742555	[727,579]	[569,220]	0	hSpCas9	negative selection	5425428
48900340	48900363	19	+	27661255	K562	viability	GCCCTGGAAAACGCCCTCTGCGG	NUCB1	ENSG00000104805	0.09808170851381542	[726,717]	[666,575]	3	dCas9-KRAB	negative selection	5497782
48900346	48900369	19	+	27661255	K562	viability	GAAAACGCCCTCTGCGGTGAAGG	NUCB1	ENSG00000104805	0.00797216318117061	[977,1084]	[948,722]	0	dCas9-KRAB	negative selection	5497783
48900380	48900403	19	+	27661255	K562	viability	GCCAGGGTTCCCATACTCTTGGG	NUCB1	ENSG00000104805	0.027878442937787296	[952,1004]	[944,669]	0	dCas9-KRAB	negative selection	5497784
48900778	48900801	19	-	27661255	K562	viability	GCATGGCAGTGTGGTCTGTGGGG	NUCB1	ENSG00000104805	0.23363228942998338	[691,837]	[789,652]	7	dCas9-KRAB	negative selection	5497785
48905817	48905840	19	+	27260156	BXPC3	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.05101469478212417	[143]	[93,138,211,190]	1	hSpCas9	negative selection	5559026
48904435	48904458	19	-	27260156	BXPC3	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.46363248279377256	[1862]	[1374,1463,1286,1526]	-7	hSpCas9	negative selection	5623282
48905788	48905811	19	+	27260156	BXPC3	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.07064895046905442	[397]	[359,311,563,539]	1	hSpCas9	negative selection	5623283
48904376	48904399	19	-	27260156	BXPC3	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.14203307600969972	[1597]	[1530,1375,1355,1824]	-3	hSpCas9	negative selection	5623284
48905817	48905840	19	+	27260156	A673	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.29890656592144094	[143]	[182,220,267,171]	7	hSpCas9	negative selection	5680277
48904435	48904458	19	-	27260156	A673	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.21694731728452887	[1862]	[2231,1588,1924,1996]	-5	hSpCas9	negative selection	5744533
48905788	48905811	19	+	27260156	A673	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.0849628742472533	[397]	[474,514,458,577]	2	hSpCas9	negative selection	5744534
48904376	48904399	19	-	27260156	A673	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.006060355860118216	[1597]	[2181,1561,2014,1985]	0	hSpCas9	negative selection	5744535
48905817	48905840	19	+	27260156	A375	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.18742572921182155	[143]	[252,293,151,92]	2	hSpCas9	negative selection	5801528
48904435	48904458	19	-	27260156	A375	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.8256421042434325	[1862]	[1350,1225,1158,1176]	-8	hSpCas9	negative selection	5865784
48905788	48905811	19	+	27260156	A375	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.16098929558286446	[397]	[630,547,616,310]	2	hSpCas9	negative selection	5865785
48904376	48904399	19	-	27260156	A375	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.07107977074346605	[1597]	[1829,1778,1782,1715]	-1	hSpCas9	negative selection	5865786
48905817	48905840	19	+	27260156	COLO741	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.35275048815675425	[143]	[152,273,267]	7	hSpCas9	negative selection	5922779
48904435	48904458	19	-	27260156	COLO741	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.4584982638957751	[1862]	[2007,1742,1483]	-7	hSpCas9	negative selection	5987035
48905788	48905811	19	+	27260156	COLO741	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.36377348956377387	[397]	[394,412,377]	-7	hSpCas9	negative selection	5987036
48904376	48904399	19	-	27260156	COLO741	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.04268527381134746	[1597]	[2450,1955,1938]	0	hSpCas9	negative selection	5987037
48905817	48905840	19	+	27260156	CAL120	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.5992703692156456	[143]	[214,330,259]	8	hSpCas9	negative selection	6044030
48904435	48904458	19	-	27260156	CAL120	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.3215542112833867	[1862]	[2112,1781,1710]	-5	hSpCas9	negative selection	6108286
48905788	48905811	19	+	27260156	CAL120	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.19590403939272807	[397]	[682,464,570]	3	hSpCas9	negative selection	6108287
48904376	48904399	19	-	27260156	CAL120	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.04592960565635451	[1597]	[2399,1871,1939]	0	hSpCas9	negative selection	6108288
48905817	48905840	19	+	27260156	CADOES1	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.696455145683226	[143]	[184,223,145,316]	9	hSpCas9	negative selection	6165281
48904435	48904458	19	-	27260156	CADOES1	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.6513406586215191	[1862]	[979,1167,1013,1256]	-8	hSpCas9	negative selection	6229537
48905788	48905811	19	+	27260156	CADOES1	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.08155257585007056	[397]	[358,465,375,364]	1	hSpCas9	negative selection	6229538
48904376	48904399	19	-	27260156	CADOES1	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.0073086041122605305	[1597]	[1260,1413,1563,1683]	0	hSpCas9	negative selection	6229539
48905817	48905840	19	+	27260156	EWS502	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.4239820447074958	[143]	[137,386,146,140]	7	hSpCas9	negative selection	6286532
48904435	48904458	19	-	27260156	EWS502	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.6374725582404155	[1862]	[1199,1196,1115,1587]	-7	hSpCas9	negative selection	6350788
48905788	48905811	19	+	27260156	EWS502	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.08153786838566954	[397]	[363,329,515,389]	-1	hSpCas9	negative selection	6350789
48904376	48904399	19	-	27260156	EWS502	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.04536142566519241	[1597]	[1428,1560,1709,1902]	-1	hSpCas9	negative selection	6350790
48905817	48905840	19	+	27260156	EW8	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.11290823574623365	[143]	[152,105,121,126]	2	hSpCas9	negative selection	6407783
48904435	48904458	19	-	27260156	EW8	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.573684097035327	[1862]	[1099,1228,900,854]	-8	hSpCas9	negative selection	6472039
48905788	48905811	19	+	27260156	EW8	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.3606183868424053	[397]	[259,234,202,314]	-6	hSpCas9	negative selection	6472040
48904376	48904399	19	-	27260156	EW8	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.03215855874374185	[1597]	[1422,1283,1140,1252]	0	hSpCas9	negative selection	6472041
48905817	48905840	19	+	27260156	CORL105	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.30059340092159936	[143]	[277,277,150,115]	5	hSpCas9	negative selection	6529034
48904435	48904458	19	-	27260156	CORL105	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.3553390436994508	[1862]	[1627,1713,1981,1535]	-6	hSpCas9	negative selection	6593290
48905788	48905811	19	+	27260156	CORL105	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.3076067553061972	[397]	[451,569,796,517]	6	hSpCas9	negative selection	6593291
48904376	48904399	19	-	27260156	CORL105	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.021850813246547807	[1597]	[1812,1719,2186,1921]	0	hSpCas9	negative selection	6593292
48905817	48905840	19	+	27260156	HS294T	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	-0.17108793032741465	[143]	[27,53,70,45]	-2	hSpCas9	negative selection	6650285
48904435	48904458	19	-	27260156	HS294T	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.9123008732339142	[1862]	[249,425,427,447]	-8	hSpCas9	negative selection	6714541
48905788	48905811	19	+	27260156	HS294T	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.14409040581060492	[397]	[144,118,126,170]	-2	hSpCas9	negative selection	6714542
48904376	48904399	19	-	27260156	HS294T	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.04185450278207625	[1597]	[528,629,583,673]	0	hSpCas9	negative selection	6714543
48905817	48905840	19	+	27260156	HCC44	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	-0.04957206743681786	[143]	[145,167,183,132]	-1	hSpCas9	negative selection	6771536
48904435	48904458	19	-	27260156	HCC44	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	0.018885594616047774	[1862]	[2245,1708,2457,2231]	0	hSpCas9	negative selection	6835792
48905788	48905811	19	+	27260156	HCC44	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.4273728320341679	[397]	[620,443,557,802]	7	hSpCas9	negative selection	6835793
48904376	48904399	19	-	27260156	HCC44	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.20580207635804193	[1597]	[2283,1904,2173,2018]	3	hSpCas9	negative selection	6835794
48905817	48905840	19	+	27260156	G402	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	-0.03862429857994498	[143]	[76,98,173,308]	0	hSpCas9	negative selection	6892787
48904435	48904458	19	-	27260156	G402	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.4991101939020608	[1862]	[1720,2168,1311,1289]	-6	hSpCas9	negative selection	6957043
48905788	48905811	19	+	27260156	G402	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.1931728314407404	[397]	[242,437,396,585]	-2	hSpCas9	negative selection	6957044
48904376	48904399	19	-	27260156	G402	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.2210855842200179	[1597]	[2048,1494,1705,1487]	-3	hSpCas9	negative selection	6957045
48905817	48905840	19	+	27260156	L33	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.27768796505321713	[143]	[141,67,119,199]	6	hSpCas9	negative selection	7014038
48904435	48904458	19	-	27260156	L33	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.2938962979056312	[1862]	[1602,621,920,1489]	-6	hSpCas9	negative selection	7078294
48905788	48905811	19	+	27260156	L33	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.2617775869339817	[397]	[333,188,352,554]	5	hSpCas9	negative selection	7078295
48904376	48904399	19	-	27260156	L33	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.14039968975701145	[1597]	[1971,646,1083,1763]	3	hSpCas9	negative selection	7078296
48905817	48905840	19	+	27260156	K562	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	-0.6533987088394821	[143]	[173,34,31,87]	-6	hSpCas9	negative selection	7135289
48904435	48904458	19	-	27260156	K562	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.9776884744034227	[1862]	[756,1068,799,744]	-8	hSpCas9	negative selection	7199545
48905788	48905811	19	+	27260156	K562	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.18856954592894346	[397]	[279,378,274,305]	-2	hSpCas9	negative selection	7199546
48904376	48904399	19	-	27260156	K562	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.02625251272081619	[1597]	[1980,1158,1641,878]	0	hSpCas9	negative selection	7199547
48905817	48905840	19	+	27260156	HT29	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	-0.08535323575295428	[143]	[258,183,89,137]	-2	hSpCas9	negative selection	7256540
48904435	48904458	19	-	27260156	HT29	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.477855173240902	[1862]	[1791,1722,1652,1376]	-7	hSpCas9	negative selection	7320796
48905788	48905811	19	+	27260156	HT29	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.21168508933975008	[397]	[372,488,428,383]	-4	hSpCas9	negative selection	7320797
48904376	48904399	19	-	27260156	HT29	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.03162492802388761	[1597]	[2074,1820,2143,1592]	0	hSpCas9	negative selection	7320798
48905817	48905840	19	+	27260156	MHHES1	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.22789847506115857	[143]	[254,112,159,219]	4	hSpCas9	negative selection	7377791
48904435	48904458	19	-	27260156	MHHES1	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.42461146704477604	[1862]	[1971,1434,1740,1193]	-7	hSpCas9	negative selection	7442047
48905788	48905811	19	+	27260156	MHHES1	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.046470716226465175	[397]	[603,494,408,373]	0	hSpCas9	negative selection	7442048
48904376	48904399	19	-	27260156	MHHES1	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.16466305679073145	[1597]	[2547,2392,1651,1622]	3	hSpCas9	negative selection	7442049
48905817	48905840	19	+	27260156	MEWO	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.22229192539705123	[143]	[149,170,148]	5	hSpCas9	negative selection	7499042
48904435	48904458	19	-	27260156	MEWO	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.2142744033989945	[1862]	[1922,1362,1302]	-5	hSpCas9	negative selection	7563298
48905788	48905811	19	+	27260156	MEWO	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.41118098114969304	[397]	[697,418,407]	8	hSpCas9	negative selection	7563299
48904376	48904399	19	-	27260156	MEWO	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.12719436537158857	[1597]	[2042,1338,1596]	3	hSpCas9	negative selection	7563300
48905817	48905840	19	+	27260156	LNCAPCLONEFGC	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.42760203817210884	[143]	[240,163,160,132]	6	hSpCas9	negative selection	7620293
48904435	48904458	19	-	27260156	LNCAPCLONEFGC	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.4008601642251559	[1862]	[1034,1301,1755,1092]	-6	hSpCas9	negative selection	7684549
48905788	48905811	19	+	27260156	LNCAPCLONEFGC	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.09065142620991293	[397]	[373,289,445,440]	1	hSpCas9	negative selection	7684550
48904376	48904399	19	-	27260156	LNCAPCLONEFGC	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.18325906555982097	[1597]	[1255,1674,2129,1589]	3	hSpCas9	negative selection	7684551
48905817	48905840	19	+	27260156	PANC0327	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.4292761419483926	[143]	[310,189,121,74]	6	hSpCas9	negative selection	7741544
48904435	48904458	19	-	27260156	PANC0327	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.5124838916155088	[1862]	[1230,1091,1272,1058]	-6	hSpCas9	negative selection	7805800
48905788	48905811	19	+	27260156	PANC0327	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.06463331264696337	[397]	[356,413,310,389]	0	hSpCas9	negative selection	7805801
48904376	48904399	19	-	27260156	PANC0327	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.17384576595264845	[1597]	[1466,1158,1224,1211]	-3	hSpCas9	negative selection	7805802
48905817	48905840	19	+	27260156	NCIH2009	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.4497317022970313	[143]	[301,123,405]	6	hSpCas9	negative selection	7862795
48904435	48904458	19	-	27260156	NCIH2009	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.8346921666292173	[1862]	[1762,1397,1275]	-7	hSpCas9	negative selection	7927051
48905788	48905811	19	+	27260156	NCIH2009	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.08047076139175555	[397]	[638,421,714]	1	hSpCas9	negative selection	7927052
48904376	48904399	19	-	27260156	NCIH2009	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.406434449232135	[1597]	[3035,2886,2965]	5	hSpCas9	negative selection	7927053
48905817	48905840	19	+	27260156	NCIH1373	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	-0.31807380015008646	[143]	[82,160,132,33]	-3	hSpCas9	negative selection	7984046
48904435	48904458	19	-	27260156	NCIH1373	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.5275635012545008	[1862]	[2354,1221,1055,346]	-5	hSpCas9	negative selection	8048302
48905788	48905811	19	+	27260156	NCIH1373	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.26113584021430947	[397]	[791,279,283,51]	-3	hSpCas9	negative selection	8048303
48904376	48904399	19	-	27260156	NCIH1373	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.12589146912653537	[1597]	[1397,2404,2290,405]	1	hSpCas9	negative selection	8048304
48905817	48905840	19	+	27260156	PATU8902	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	-0.6618145180888859	[143]	[129,346,22,20]	-6	hSpCas9	negative selection	8105297
48904435	48904458	19	-	27260156	PATU8902	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.5735359769164559	[1862]	[1680,1500,1579,2307]	-5	hSpCas9	negative selection	8169553
48905788	48905811	19	+	27260156	PATU8902	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.29252760276789647	[397]	[512,530,395,370]	-3	hSpCas9	negative selection	8169554
48904376	48904399	19	-	27260156	PATU8902	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.17781837439901937	[1597]	[2319,3162,2540,1956]	1	hSpCas9	negative selection	8169555
48905817	48905840	19	+	27260156	PANC1	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.45519434567447936	[143]	[106,156,235,173]	7	hSpCas9	negative selection	8226548
48904435	48904458	19	-	27260156	PANC1	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	0.025438949376421993	[1862]	[1767,1954,1609,1276]	0	hSpCas9	negative selection	8290804
48905788	48905811	19	+	27260156	PANC1	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.45378907000690877	[397]	[412,708,532,290]	7	hSpCas9	negative selection	8290805
48904376	48904399	19	-	27260156	PANC1	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.01729551334824664	[1597]	[1672,1520,1064,1305]	0	hSpCas9	negative selection	8290806
48905817	48905840	19	+	27260156	PANC0813	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.12641411273777736	[143]	[140,162,133,289]	2	hSpCas9	negative selection	8347799
48904435	48904458	19	-	27260156	PANC0813	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.3395775736391067	[1862]	[1488,1857,1441,2081]	-5	hSpCas9	negative selection	8412055
48905788	48905811	19	+	27260156	PANC0813	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.3614599825136244	[397]	[622,538,644,596]	6	hSpCas9	negative selection	8412056
48904376	48904399	19	-	27260156	PANC0813	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.2919872942216304	[1597]	[2557,2484,2081,2097]	5	hSpCas9	negative selection	8412057
48905817	48905840	19	+	27260156	RDES	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.01274760517392659	[143]	[183,69,188,236]	0	hSpCas9	negative selection	8469050
48904435	48904458	19	-	27260156	RDES	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.6066601097808881	[1862]	[1119,1313,1603,1665]	-8	hSpCas9	negative selection	8533306
48905788	48905811	19	+	27260156	RDES	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.004097540702343666	[397]	[465,362,526,464]	0	hSpCas9	negative selection	8533307
48904376	48904399	19	-	27260156	RDES	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.14480710997933355	[1597]	[1201,1800,1772,1959]	-2	hSpCas9	negative selection	8533308
48905817	48905840	19	+	27260156	PC3	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	-0.11784711658393587	[143]	[105,151,244,60]	-3	hSpCas9	negative selection	8590301
48904435	48904458	19	-	27260156	PC3	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.3732179774697475	[1862]	[924,1559,2479,1239]	-7	hSpCas9	negative selection	8654557
48905788	48905811	19	+	27260156	PC3	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.19359903670786785	[397]	[313,454,547,550]	4	hSpCas9	negative selection	8654558
48904376	48904399	19	-	27260156	PC3	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.10768061795259443	[1597]	[996,1619,3083,1868]	2	hSpCas9	negative selection	8654559
48905817	48905840	19	+	27260156	PATU8988T	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.3070408013690855	[143]	[176,154,258,87]	5	hSpCas9	negative selection	8711552
48904435	48904458	19	-	27260156	PATU8988T	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.4415094361831524	[1862]	[1611,1655,768,1301]	-6	hSpCas9	negative selection	8775808
48905788	48905811	19	+	27260156	PATU8988T	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.05457018491413984	[397]	[450,573,209,379]	0	hSpCas9	negative selection	8775809
48904376	48904399	19	-	27260156	PATU8988T	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.15280842417151086	[1597]	[1082,1516,1594,1367]	-3	hSpCas9	negative selection	8775810
48905817	48905840	19	+	27260156	T47D	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.23070861793703745	[143]	[182,183,202,218]	5	hSpCas9	negative selection	8832803
48904435	48904458	19	-	27260156	T47D	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.47812732583634765	[1862]	[1683,1386,1545,1632]	-7	hSpCas9	negative selection	8897059
48905788	48905811	19	+	27260156	T47D	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.07776841347106986	[397]	[368,481,437,464]	-2	hSpCas9	negative selection	8897060
48904376	48904399	19	-	27260156	T47D	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	-0.08670935703384064	[1597]	[1735,1697,1749,1834]	-2	hSpCas9	negative selection	8897061
48905817	48905840	19	+	27260156	SU8686	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.3092984867465729	[143]	[204,163,196,131]	5	hSpCas9	negative selection	8954054
48904435	48904458	19	-	27260156	SU8686	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.6494746042025386	[1862]	[1004,1077,1272,1419]	-7	hSpCas9	negative selection	9018310
48905788	48905811	19	+	27260156	SU8686	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.04050351375108299	[397]	[317,393,366,472]	0	hSpCas9	negative selection	9018311
48904376	48904399	19	-	27260156	SU8686	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.08375662647994653	[1597]	[1566,1544,1640,2037]	1	hSpCas9	negative selection	9018312
48905817	48905840	19	+	27260156	SKES1	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.2063427225146346	[143]	[189,146,103,215]	4	hSpCas9	negative selection	9075305
48904435	48904458	19	-	27260156	SKES1	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.41056389956542416	[1862]	[1451,1642,1361,1183]	-7	hSpCas9	negative selection	9139561
48905788	48905811	19	+	27260156	SKES1	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.2742536341127802	[397]	[561,437,605,331]	6	hSpCas9	negative selection	9139562
48904376	48904399	19	-	27260156	SKES1	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.13079338395784212	[1597]	[1690,2281,1643,1440]	3	hSpCas9	negative selection	9139563
48905817	48905840	19	+	27260156	TOV112D	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.07030214732024187	[143]	[112,247,77,185]	1	hSpCas9	negative selection	9196556
48904435	48904458	19	-	27260156	TOV112D	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.44243933757694687	[1862]	[1087,1672,1337,1438]	-7	hSpCas9	negative selection	9260812
48905788	48905811	19	+	27260156	TOV112D	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.11793306126924688	[397]	[405,507,312,281]	-2	hSpCas9	negative selection	9260813
48904376	48904399	19	-	27260156	TOV112D	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.05310459550013924	[1597]	[2018,1876,1431,1401]	1	hSpCas9	negative selection	9260814
48905817	48905840	19	+	27260156	TC71	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.43999965918993866	[143]	[243,203,207,178]	8	hSpCas9	negative selection	9317807
48904435	48904458	19	-	27260156	TC71	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.2658152453030662	[1862]	[1463,1653,1728,1807]	-6	hSpCas9	negative selection	9382063
48905788	48905811	19	+	27260156	TC71	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	0.10635393387160216	[397]	[560,451,373,449]	2	hSpCas9	negative selection	9382064
48904376	48904399	19	-	27260156	TC71	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.04679521768371786	[1597]	[1834,1721,1528,2012]	1	hSpCas9	negative selection	9382065
48905817	48905840	19	+	27260156	TC32	viability	TCAAGCGACAGGAGGTGTCACGG	NUCB1	ENSG00000104805	0.25434644462819644	[143]	[157,86,239,195]	4	hSpCas9	negative selection	9439058
48904435	48904458	19	-	27260156	TC32	viability	CACCTTGATGTCCTCCGCATTGG	NUCB1	ENSG00000104805	-0.6162519722597435	[1862]	[946,748,1575,1501]	-8	hSpCas9	negative selection	9503314
48905788	48905811	19	+	27260156	TC32	viability	CCACCACGTCCGCACCAAGCTGG	NUCB1	ENSG00000104805	-0.2909487778303447	[397]	[231,264,374,372]	-5	hSpCas9	negative selection	9503315
48904376	48904399	19	-	27260156	TC32	viability	CCAGTACATCGATGACCTCCTGG	NUCB1	ENSG00000104805	0.04679450866452983	[1597]	[1223,1436,2082,1540]	0	hSpCas9	negative selection	9503316
48900913	48900936	19	-	27869803	HPAFII	viability after 27 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.9662583618843226	[270]	[357,211,NaN]	7	hSpCas9	negative selection	9569049
48905857	48905880	19	+	27869803	HPAFII	viability after 27 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.6720757226213298	[204]	[258,98,NaN]	5	hSpCas9	negative selection	9569050
48919065	48919088	19	+	27869803	HPAFII	viability after 27 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	1.1245411945373494	[219]	[189,303,NaN]	8	hSpCas9	negative selection	9569051
48900913	48900936	19	-	27869803	HPAFII	viability after 15 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.5647759646386484	[270]	[682,273,NaN]	6	hSpCas9	negative selection	9651498
48905857	48905880	19	+	27869803	HPAFII	viability after 15 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.2596550436453801	[204]	[420,165,NaN]	3	hSpCas9	negative selection	9651499
48919065	48919088	19	+	27869803	HPAFII	viability after 15 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	-0.5709128849450419	[219]	[189,139,NaN]	-6	hSpCas9	negative selection	9651500
48900913	48900936	19	-	27869803	ASPC1	viability after 36 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.8643847731645765	[629]	[618,321,304]	8	hSpCas9	negative selection	9733947
48905857	48905880	19	+	27869803	ASPC1	viability after 36 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	-0.8279978890777417	[458]	[229,77,0]	-7	hSpCas9	negative selection	9733948
48919065	48919088	19	+	27869803	ASPC1	viability after 36 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	0.5926473313990039	[590]	[591,170,221]	6	hSpCas9	negative selection	9733949
48900913	48900936	19	-	27869803	PATU8988S	viability after 35 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.5734069729258516	[608]	[354,374,NaN]	6	hSpCas9	negative selection	9816396
48905857	48905880	19	+	27869803	PATU8988S	viability after 35 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	-0.8971415760119084	[283]	[24,97,NaN]	-7	hSpCas9	negative selection	9816397
48919065	48919088	19	+	27869803	PATU8988S	viability after 35 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	-1.4149650134353393	[525]	[55,102,NaN]	-8	hSpCas9	negative selection	9816398
48900913	48900936	19	-	27869803	PATU8988S	viability after 31 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.21242173945009168	[608]	[261,305,NaN]	2	hSpCas9	negative selection	9898845
48905857	48905880	19	+	27869803	PATU8988S	viability after 31 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	-0.531391418695865	[283]	[36,130,NaN]	-5	hSpCas9	negative selection	9898846
48919065	48919088	19	+	27869803	PATU8988S	viability after 31 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	-1.5758035570924354	[525]	[61,80,NaN]	-8	hSpCas9	negative selection	9898847
48900913	48900936	19	-	27869803	HPAFII	viability after 35 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.6656367239588024	[270]	[290,134,NaN]	4	hSpCas9	negative selection	9981294
48905857	48905880	19	+	27869803	HPAFII	viability after 35 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	1.301271345322154	[204]	[251,259,NaN]	8	hSpCas9	negative selection	9981295
48919065	48919088	19	+	27869803	HPAFII	viability after 35 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	1.5010949659980062	[219]	[112,542,NaN]	8	hSpCas9	negative selection	9981296
48900913	48900936	19	-	27869803	HPAFII	viability after 31 days	TCACGGGACTCTCAGTCGCAGGG	NUCB1	ENSG00000104805	0.4963442177859077	[270]	[248,176,NaN]	3	hSpCas9	negative selection	10063743
48905857	48905880	19	+	27869803	HPAFII	viability after 31 days	GGCCAAGATGGACGCCGAGCAGG	NUCB1	ENSG00000104805	0.9341261975214602	[204]	[215,223,NaN]	7	hSpCas9	negative selection	10063744
48919065	48919088	19	+	27869803	HPAFII	viability after 31 days	CGACATGCGGGAGATGGAGGAGG	NUCB1	ENSG00000104805	1.2750823114735201	[219]	[193,412,NaN]	8	hSpCas9	negative selection	10063745
48904424	48904447	19	+	28162770	P31FUJ	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	-0.16867186699466308	[175]	[183]	-2	hSpCas9	negative selection	10203261
48919059	48919082	19	+	28162770	P31FUJ	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	0.5053906931358298	[234]	[391]	6	hSpCas9	negative selection	10203262
48919256	48919279	19	+	28162770	P31FUJ	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	-1.0952986806644436	[19]	[10]	-6	hSpCas9	negative selection	10203263
48921162	48921185	19	+	28162770	P31FUJ	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	-0.45846233958473737	[220]	[188]	-4	hSpCas9	negative selection	10203264
48904361	48904384	19	+	28162770	P31FUJ	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.06621149852498165	[329]	[405]	0	hSpCas9	negative selection	10203265
48904373	48904396	19	-	28162770	P31FUJ	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.257719836618708	[291]	[286]	-2	hSpCas9	negative selection	10203266
48905809	48905832	19	+	28162770	P31FUJ	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	0.3893132947242435	[229]	[353]	4	hSpCas9	negative selection	10203267
48919041	48919064	19	+	28162770	P31FUJ	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	0.7374504521915695	[48]	[95]	8	hSpCas9	negative selection	10203268
48904424	48904447	19	+	28162770	TF1	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	NaN	[NaN]	[128]	1	hSpCas9	negative selection	10372627
48919059	48919082	19	+	28162770	TF1	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10372628
48919256	48919279	19	+	28162770	TF1	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10372629
48921162	48921185	19	+	28162770	TF1	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	NaN	[NaN]	[245]	1	hSpCas9	negative selection	10372630
48904361	48904384	19	+	28162770	TF1	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	NaN	[NaN]	[373]	1	hSpCas9	negative selection	10372631
48904373	48904396	19	-	28162770	TF1	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	NaN	[NaN]	[315]	1	hSpCas9	negative selection	10372632
48905809	48905832	19	+	28162770	TF1	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10372633
48919041	48919064	19	+	28162770	TF1	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10372634
48904424	48904447	19	+	28162770	SKM1	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	-0.26946067499322685	[59]	[87]	-2	hSpCas9	negative selection	10541993
48919059	48919082	19	+	28162770	SKM1	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	-0.15005589570620942	[58]	[93]	-1	hSpCas9	negative selection	10541994
48919256	48919279	19	+	28162770	SKM1	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	0.40039072331444236	[5]	[13]	4	hSpCas9	negative selection	10541995
48921162	48921185	19	+	28162770	SKM1	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	0.054615886472712386	[60]	[111]	0	hSpCas9	negative selection	10541996
48904361	48904384	19	+	28162770	SKM1	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.5683133718456069	[102]	[269]	5	hSpCas9	negative selection	10541997
48904373	48904396	19	-	28162770	SKM1	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	0.16445177014004664	[106]	[211]	1	hSpCas9	negative selection	10541998
48905809	48905832	19	+	28162770	SKM1	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	1.0119883505390654	[45]	[163]	8	hSpCas9	negative selection	10541999
48919041	48919064	19	+	28162770	SKM1	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	-0.8220016980220053	[7]	[7]	-6	hSpCas9	negative selection	10542000
48904424	48904447	19	+	28162770	SKM1	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	-0.26946067499322685	[59]	[87]	-2	hSpCas9	negative selection	10711359
48919059	48919082	19	+	28162770	SKM1	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	-0.15005589570620942	[58]	[93]	-1	hSpCas9	negative selection	10711360
48919256	48919279	19	+	28162770	SKM1	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	0.40039072331444236	[5]	[13]	4	hSpCas9	negative selection	10711361
48921162	48921185	19	+	28162770	SKM1	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	0.054615886472712386	[60]	[111]	0	hSpCas9	negative selection	10711362
48904361	48904384	19	+	28162770	SKM1	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.5683133718456069	[102]	[269]	5	hSpCas9	negative selection	10711363
48904373	48904396	19	-	28162770	SKM1	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	0.16445177014004664	[106]	[211]	1	hSpCas9	negative selection	10711364
48905809	48905832	19	+	28162770	SKM1	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	1.0119883505390654	[45]	[163]	8	hSpCas9	negative selection	10711365
48919041	48919064	19	+	28162770	SKM1	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	-0.8220016980220053	[7]	[7]	-6	hSpCas9	negative selection	10711366
48904424	48904447	19	+	28162770	PL21	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	-0.5428247202983292	[240]	[71]	-4	hSpCas9	negative selection	10880725
48919059	48919082	19	+	28162770	PL21	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	0.17655279417170422	[184]	[90]	1	hSpCas9	negative selection	10880726
48919256	48919279	19	+	28162770	PL21	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	-1.4628253982331096	[18]	[2]	-7	hSpCas9	negative selection	10880727
48921162	48921185	19	+	28162770	PL21	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	0.16330284630894876	[237]	[115]	1	hSpCas9	negative selection	10880728
48904361	48904384	19	+	28162770	PL21	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	-0.2578500299740707	[499]	[181]	-2	hSpCas9	negative selection	10880729
48904373	48904396	19	-	28162770	PL21	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	0.22573943772561655	[390]	[198]	2	hSpCas9	negative selection	10880730
48905809	48905832	19	+	28162770	PL21	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	-1.113751161332624	[178]	[35]	-6	hSpCas9	negative selection	10880731
48919041	48919064	19	+	28162770	PL21	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	-0.3303751022094601	[25]	[8]	-2	hSpCas9	negative selection	10880732
48904424	48904447	19	+	28162770	P31FUJ	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	-0.16867186699466308	[175]	[183]	-2	hSpCas9	negative selection	11050091
48919059	48919082	19	+	28162770	P31FUJ	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	0.5053906931358298	[234]	[391]	6	hSpCas9	negative selection	11050092
48919256	48919279	19	+	28162770	P31FUJ	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	-1.0952986806644436	[19]	[10]	-6	hSpCas9	negative selection	11050093
48921162	48921185	19	+	28162770	P31FUJ	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	-0.45846233958473737	[220]	[188]	-4	hSpCas9	negative selection	11050094
48904361	48904384	19	+	28162770	P31FUJ	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.06621149852498165	[329]	[405]	0	hSpCas9	negative selection	11050095
48904373	48904396	19	-	28162770	P31FUJ	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.257719836618708	[291]	[286]	-2	hSpCas9	negative selection	11050096
48905809	48905832	19	+	28162770	P31FUJ	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	0.3893132947242435	[229]	[353]	4	hSpCas9	negative selection	11050097
48919041	48919064	19	+	28162770	P31FUJ	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	0.7374504521915695	[48]	[95]	8	hSpCas9	negative selection	11050098
48904424	48904447	19	+	28162770	OCIAML5	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	-0.6594214929216009	[104]	[119]	-4	hSpCas9	negative selection	11219457
48919059	48919082	19	+	28162770	OCIAML5	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	-0.2765643993919073	[152]	[227]	-2	hSpCas9	negative selection	11219458
48919256	48919279	19	+	28162770	OCIAML5	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	-4.852066570863997	[15]	[0]	-9	hSpCas9	negative selection	11219459
48921162	48921185	19	+	28162770	OCIAML5	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	0.9769472323233803	[84]	[301]	8	hSpCas9	negative selection	11219460
48904361	48904384	19	+	28162770	OCIAML5	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	-0.021991572306309326	[251]	[447]	0	hSpCas9	negative selection	11219461
48904373	48904396	19	-	28162770	OCIAML5	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.42043885291383143	[280]	[378]	-3	hSpCas9	negative selection	11219462
48905809	48905832	19	+	28162770	OCIAML5	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	-0.8694486490922335	[166]	[164]	-5	hSpCas9	negative selection	11219463
48919041	48919064	19	+	28162770	OCIAML5	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	0.46986152402336523	[33]	[84]	4	hSpCas9	negative selection	11219464
48904424	48904447	19	+	28162770	EOL1	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	0.9320618252278412	[382]	[384]	7	hSpCas9	negative selection	11388823
48919059	48919082	19	+	28162770	EOL1	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	-0.4527570803532012	[238]	[91]	-3	hSpCas9	negative selection	11388824
48919256	48919279	19	+	28162770	EOL1	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	0.9663679472651614	[33]	[34]	8	hSpCas9	negative selection	11388825
48921162	48921185	19	+	28162770	EOL1	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	1.167404295466698	[359]	[425]	8	hSpCas9	negative selection	11388826
48904361	48904384	19	+	28162770	EOL1	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	-0.6125484178853631	[829]	[285]	-4	hSpCas9	negative selection	11388827
48904373	48904396	19	-	28162770	EOL1	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.9595028476798728	[704]	[190]	-6	hSpCas9	negative selection	11388828
48905809	48905832	19	+	28162770	EOL1	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	0.5304330456555113	[250]	[190]	5	hSpCas9	negative selection	11388829
48919041	48919064	19	+	28162770	EOL1	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	-2.3608544472917137	[38]	[3]	-8	hSpCas9	negative selection	11388830
48904424	48904447	19	+	28162770	MOLM13	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	1.5753023239655581	[206]	[445]	9	hSpCas9	negative selection	11558189
48919059	48919082	19	+	28162770	MOLM13	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	-0.17562530153169037	[263]	[168]	-1	hSpCas9	negative selection	11558190
48919256	48919279	19	+	28162770	MOLM13	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	-4.0556725745124345	[22]	[0]	-9	hSpCas9	negative selection	11558191
48921162	48921185	19	+	28162770	MOLM13	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	0.016015114085363547	[356]	[260]	0	hSpCas9	negative selection	11558192
48904361	48904384	19	+	28162770	MOLM13	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.17549679611198643	[555]	[453]	1	hSpCas9	negative selection	11558193
48904373	48904396	19	-	28162770	MOLM13	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.33287286320259646	[654]	[375]	-2	hSpCas9	negative selection	11558194
48905809	48905832	19	+	28162770	MOLM13	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	-0.6384195206017619	[182]	[84]	-4	hSpCas9	negative selection	11558195
48919041	48919064	19	+	28162770	MOLM13	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	0.38300048395806563	[34]	[32]	3	hSpCas9	negative selection	11558196
48904424	48904447	19	+	28162770	HEL	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	-0.376120195250959	[230]	[113]	-3	hSpCas9	negative selection	11727555
48919059	48919082	19	+	28162770	HEL	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	0.7044018518841617	[228]	[238]	6	hSpCas9	negative selection	11727556
48919256	48919279	19	+	28162770	HEL	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	-0.3572611679996429	[33]	[16]	-2	hSpCas9	negative selection	11727557
48921162	48921185	19	+	28162770	HEL	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	0.7609779442296795	[280]	[304]	6	hSpCas9	negative selection	11727558
48904361	48904384	19	+	28162770	HEL	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.6644747616516518	[526]	[534]	6	hSpCas9	negative selection	11727559
48904373	48904396	19	-	28162770	HEL	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.10638282447178693	[436]	[259]	-1	hSpCas9	negative selection	11727560
48905809	48905832	19	+	28162770	HEL	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	0.8400402723739743	[231]	[265]	7	hSpCas9	negative selection	11727561
48919041	48919064	19	+	28162770	HEL	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	0.08085994439224198	[30]	[20]	0	hSpCas9	negative selection	11727562
48904424	48904447	19	+	28162770	MV411	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	-1.1890796759065199	[202]	[74]	-7	hSpCas9	negative selection	11896921
48919059	48919082	19	+	28162770	MV411	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	-0.6163580656189134	[201]	[110]	-4	hSpCas9	negative selection	11896922
48919256	48919279	19	+	28162770	MV411	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	0.9255094558954129	[14]	[23]	8	hSpCas9	negative selection	11896923
48921162	48921185	19	+	28162770	MV411	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	-0.05438933804807754	[195]	[158]	0	hSpCas9	negative selection	11896924
48904361	48904384	19	+	28162770	MV411	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.04812874255936861	[371]	[323]	0	hSpCas9	negative selection	11896925
48904373	48904396	19	-	28162770	MV411	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.8658620133317908	[330]	[152]	-5	hSpCas9	negative selection	11896926
48905809	48905832	19	+	28162770	MV411	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	0.2980636238527434	[167]	[173]	2	hSpCas9	negative selection	11896927
48919041	48919064	19	+	28162770	MV411	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	-1.4687694832166334	[45]	[13]	-7	hSpCas9	negative selection	11896928
48904424	48904447	19	+	28162770	MONOMAC1	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	0.1758751765466136	[138]	[179]	1	hSpCas9	negative selection	12066287
48919059	48919082	19	+	28162770	MONOMAC1	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	-0.592965523390693	[124]	[94]	-5	hSpCas9	negative selection	12066288
48919256	48919279	19	+	28162770	MONOMAC1	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	0.2180006522192901	[5]	[7]	2	hSpCas9	negative selection	12066289
48921162	48921185	19	+	28162770	MONOMAC1	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	0.28132658758811946	[116]	[162]	3	hSpCas9	negative selection	12066290
48904361	48904384	19	+	28162770	MONOMAC1	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.12696557606566716	[277]	[347]	1	hSpCas9	negative selection	12066291
48904373	48904396	19	-	28162770	MONOMAC1	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	0.2859536805603251	[253]	[354]	3	hSpCas9	negative selection	12066292
48905809	48905832	19	+	28162770	MONOMAC1	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	-0.0851439669886563	[123]	[133]	0	hSpCas9	negative selection	12066293
48919041	48919064	19	+	28162770	MONOMAC1	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	2.510782401447136	[14]	[97]	9	hSpCas9	negative selection	12066294
48904424	48904447	19	+	28162770	OCIAML2	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	0.08470750636971663	[40]	[240]	0	hSpCas9	negative selection	12235653
48919059	48919082	19	+	28162770	OCIAML2	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	0.42014110500308044	[35]	[266]	4	hSpCas9	negative selection	12235654
48919256	48919279	19	+	28162770	OCIAML2	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	-1.956056652412403	[6]	[9]	-8	hSpCas9	negative selection	12235655
48921162	48921185	19	+	28162770	OCIAML2	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	-0.34134680829719477	[63]	[279]	-3	hSpCas9	negative selection	12235656
48904361	48904384	19	+	28162770	OCIAML2	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	0.03616106132188279	[78]	[448]	0	hSpCas9	negative selection	12235657
48904373	48904396	19	-	28162770	OCIAML2	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.5738990958538643	[75]	[282]	-4	hSpCas9	negative selection	12235658
48905809	48905832	19	+	28162770	OCIAML2	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	-0.2955431186840699	[30]	[139]	-2	hSpCas9	negative selection	12235659
48919041	48919064	19	+	28162770	OCIAML2	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	0.7310040359274894	[4]	[45]	7	hSpCas9	negative selection	12235660
48904424	48904447	19	+	28162770	OCIAML3	viability	GCTGCAGGCTGCCAATGCGGAGG	NUCB1	ENSG00000104805	1.4212591163291473	[46]	[379]	9	hSpCas9	negative selection	12405019
48919059	48919082	19	+	28162770	OCIAML3	viability	GGAGGACGACATGCGGGAGATGG	NUCB1	ENSG00000104805	0.009333389711847651	[51]	[157]	0	hSpCas9	negative selection	12405020
48919256	48919279	19	+	28162770	OCIAML3	viability	GGAGTTTGGGGACACCGGGGAGG	NUCB1	ENSG00000104805	-0.9419309437444698	[6]	[10]	-6	hSpCas9	negative selection	12405021
48921162	48921185	19	+	28162770	OCIAML3	viability	GATGCACCCTGCCTACACCGAGG	NUCB1	ENSG00000104805	0.5352753766208033	[47]	[209]	5	hSpCas9	negative selection	12405022
48904361	48904384	19	+	28162770	OCIAML3	viability	CTACCACCGGTACCTCCAGGAGG	NUCB1	ENSG00000104805	-0.6916184369505856	[106]	[199]	-5	hSpCas9	negative selection	12405023
48904373	48904396	19	-	28162770	OCIAML3	viability	GTACATCGATGACCTCCTGGAGG	NUCB1	ENSG00000104805	-0.4618130279592936	[98]	[216]	-4	hSpCas9	negative selection	12405024
48905809	48905832	19	+	28162770	OCIAML3	viability	GGATGAGCTCAAGCGACAGGAGG	NUCB1	ENSG00000104805	0.30546548372187227	[51]	[193]	3	hSpCas9	negative selection	12405025
48919041	48919064	19	+	28162770	OCIAML3	viability	GTACGACCCAAAGAATGAGGAGG	NUCB1	ENSG00000104805	-2.763932641766476	[17]	[7]	-9	hSpCas9	negative selection	12405026