Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4931
• Symbol:NVL
• Description:nuclear VCP like

DataSource: http://genomecrispr.dkfz.de/#!/results/NVL

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
224236504	224236527	1	+	26472758	Jiyoye	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-2.220097924073247	[172]	[27]	-8	hSpCas9	negative selection	112820
224286036	224286059	1	+	26472758	Jiyoye	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-3.0078621177729703	[191]	[17]	-9	hSpCas9	negative selection	112821
224303818	224303841	1	-	26472758	Jiyoye	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-2.2815350440531117	[244]	[37]	-8	hSpCas9	negative selection	112822
224303770	224303793	1	+	26472758	Jiyoye	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-2.1403124137966203	[75]	[12]	-8	hSpCas9	negative selection	112823
224289509	224289532	1	-	26472758	Jiyoye	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-2.639517853942168	[156]	[18]	-9	hSpCas9	negative selection	112824
224233212	224233235	1	-	26472758	Jiyoye	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-0.704717498565024	[133]	[61]	-5	hSpCas9	negative selection	112825
224304755	224304778	1	-	26472758	Jiyoye	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-3.2481764471066805	[314]	[24]	-9	hSpCas9	negative selection	112826
224303745	224303768	1	+	26472758	Jiyoye	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-2.293264336635219	[64]	[9]	-8	hSpCas9	negative selection	112827
224300561	224300584	1	-	26472758	Jiyoye	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	5.107615099646965	[0]	[25]	9	hSpCas9	negative selection	112828
224287783	224287806	1	-	26472758	Jiyoye	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-2.592824618494127	[7]	[0]	-9	hSpCas9	negative selection	112829
224236504	224236527	1	+	26472758	KBM7	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-2.214087190350929	[518,431]	[57,38]	-8	hSpCas9	negative selection	303938
224286036	224286059	1	+	26472758	KBM7	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-1.8455649611130154	[672,400]	[72,64]	-8	hSpCas9	negative selection	303939
224303818	224303841	1	-	26472758	KBM7	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.6946526698812379	[1146,820]	[193,93]	-8	hSpCas9	negative selection	303940
224303770	224303793	1	+	26472758	KBM7	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-2.0617192079921915	[434,325]	[71,15]	-8	hSpCas9	negative selection	303941
224289509	224289532	1	-	26472758	KBM7	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-1.8615807463093867	[582,427]	[60,67]	-8	hSpCas9	negative selection	303942
224233212	224233235	1	-	26472758	KBM7	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-0.7734341513654439	[844,609]	[267,134]	-6	hSpCas9	negative selection	303943
224304755	224304778	1	-	26472758	KBM7	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-2.6026418941144516	[1021,863]	[58,84]	-9	hSpCas9	negative selection	303944
224303745	224303768	1	+	26472758	KBM7	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-1.5898798059197476	[381,383]	[85,36]	-8	hSpCas9	negative selection	303945
224300561	224300584	1	-	26472758	KBM7	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.48061100682094815	[149,134]	[66,30]	-4	hSpCas9	negative selection	303946
224287783	224287806	1	-	26472758	KBM7	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-6.35806742150191	[193,156]	[0,0]	-9	hSpCas9	negative selection	303947
224236504	224236527	1	+	26472758	Raji	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-2.677718579836877	[192]	[6]	-9	hSpCas9	negative selection	495056
224286036	224286059	1	+	26472758	Raji	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-3.389803005259116	[270]	[5]	-9	hSpCas9	negative selection	495057
224303818	224303841	1	-	26472758	Raji	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-2.6574880553624913	[434]	[15]	-9	hSpCas9	negative selection	495058
224303770	224303793	1	+	26472758	Raji	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-2.026472211361191	[157]	[8]	-8	hSpCas9	negative selection	495059
224289509	224289532	1	-	26472758	Raji	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-2.0758382886821707	[217]	[11]	-8	hSpCas9	negative selection	495060
224233212	224233235	1	-	26472758	Raji	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-1.3520480832636979	[373]	[33]	-7	hSpCas9	negative selection	495061
224304755	224304778	1	-	26472758	Raji	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-3.050468633768138	[713]	[19]	-9	hSpCas9	negative selection	495062
224303745	224303768	1	+	26472758	Raji	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-1.2314183780781591	[171]	[16]	-7	hSpCas9	negative selection	495063
224300561	224300584	1	-	26472758	Raji	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.9399221794047575	[123]	[14]	-6	hSpCas9	negative selection	495064
224287783	224287806	1	-	26472758	Raji	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-1.4004111048250965	[90]	[7]	-7	hSpCas9	negative selection	495065
224236504	224236527	1	+	26472758	K562	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-3.364390515009077	[426]	[34]	-8	hSpCas9	negative selection	686174
224286036	224286059	1	+	26472758	K562	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-3.4827658457071737	[489]	[36]	-8	hSpCas9	negative selection	686175
224303818	224303841	1	-	26472758	K562	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-2.036258638954597	[723]	[148]	-7	hSpCas9	negative selection	686176
224303770	224303793	1	+	26472758	K562	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-6.950338126755801	[292]	[1]	-9	hSpCas9	negative selection	686177
224289509	224289532	1	-	26472758	K562	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-5.219105645604733	[352]	[7]	-9	hSpCas9	negative selection	686178
224233212	224233235	1	-	26472758	K562	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-1.7798560184565688	[898]	[220]	-7	hSpCas9	negative selection	686179
224304755	224304778	1	-	26472758	K562	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-4.1448421366789745	[942]	[44]	-9	hSpCas9	negative selection	686180
224303745	224303768	1	+	26472758	K562	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-2.2983155376654123	[302]	[51]	-8	hSpCas9	negative selection	686181
224300561	224300584	1	-	26472758	K562	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.4518005241564502	[127]	[78]	-3	hSpCas9	negative selection	686182
224287783	224287806	1	-	26472758	K562	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-3.2999017885573636	[104]	[8]	-8	hSpCas9	negative selection	686183
224289483	224289506	1	-	26627737	DLD1	viability	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.1172177546767945	[874]	[115,50,196]	-7	hSpCas9	negative selection	769322
224294319	224294342	1	+	26627737	DLD1	viability	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-3.133181126038127	[1248]	[48,72,16]	-9	hSpCas9	negative selection	769325
224303803	224303826	1	-	26627737	DLD1	viability	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	0.8613681392790364	[410]	[295,264,152]	8	hSpCas9	negative selection	769326
224304800	224304823	1	-	26627737	DLD1	viability	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-0.7596741022520072	[268]	[17,50,75]	-6	hSpCas9	negative selection	769327
224308091	224308114	1	-	26627737	DLD1	viability	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-0.39322999243424717	[525]	[160,157,66]	-4	hSpCas9	negative selection	769328
224330052	224330075	1	+	26627737	DLD1	viability	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-0.28758190743838075	[365]	[23,198,66]	-3	hSpCas9	negative selection	769329
224289483	224289506	1	-	26627737	GBM cells	viability after 5 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-0.588782233194259	[508]	[214,147]	-7	hSpCas9	negative selection	851637
224294319	224294342	1	+	26627737	GBM cells	viability after 5 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-1.6053607802699097	[677]	[88,149]	-9	hSpCas9	negative selection	851640
224303803	224303826	1	-	26627737	GBM cells	viability after 5 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-0.21329562870033958	[146]	[69,65]	-3	hSpCas9	negative selection	851641
224304800	224304823	1	-	26627737	GBM cells	viability after 5 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.200621798665229	[179]	[58,24]	-9	hSpCas9	negative selection	851642
224308091	224308114	1	-	26627737	GBM cells	viability after 5 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-0.6329745101300512	[466]	[142,179]	-7	hSpCas9	negative selection	851643
224330052	224330075	1	+	26627737	GBM cells	viability after 5 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.000781219318629	[249]	[52,80]	-9	hSpCas9	negative selection	851644
224289483	224289506	1	-	26627737	GBM cells	viability after 13 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-2.010457766208643	[508]	[51,81]	-9	hSpCas9	negative selection	933952
224294319	224294342	1	+	26627737	GBM cells	viability after 13 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-2.463614345392351	[677]	[69,63]	-9	hSpCas9	negative selection	933955
224303803	224303826	1	-	26627737	GBM cells	viability after 13 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-0.5800733219797338	[146]	[70,38]	-6	hSpCas9	negative selection	933956
224304800	224304823	1	-	26627737	GBM cells	viability after 13 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.0610413723656453	[179]	[80,18]	-8	hSpCas9	negative selection	933957
224308091	224308114	1	-	26627737	GBM cells	viability after 13 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-1.8894683363394216	[466]	[90,49]	-9	hSpCas9	negative selection	933958
224330052	224330075	1	+	26627737	GBM cells	viability after 13 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.0764064972858858	[249]	[17,101]	-8	hSpCas9	negative selection	933959
224289483	224289506	1	-	26627737	GBM cells	viability after 21 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.404389677595975	[508]	[116,92]	-8	hSpCas9	negative selection	1016267
224294319	224294342	1	+	26627737	GBM cells	viability after 21 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-3.6953968278109137	[677]	[29,26]	-9	hSpCas9	negative selection	1016270
224303803	224303826	1	-	26627737	GBM cells	viability after 21 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-0.5427501412502578	[146]	[58,50]	-5	hSpCas9	negative selection	1016271
224304800	224304823	1	-	26627737	GBM cells	viability after 21 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-2.4878432560755934	[179]	[18,15]	-9	hSpCas9	negative selection	1016272
224308091	224308114	1	-	26627737	GBM cells	viability after 21 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-2.772834269088708	[466]	[45,28]	-9	hSpCas9	negative selection	1016273
224330052	224330075	1	+	26627737	GBM cells	viability after 21 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.4084186403974055	[249]	[58,43]	-8	hSpCas9	negative selection	1016274
224289483	224289506	1	-	26627737	RPE1	viability after 9 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.6686119176053202	[2598]	[320,171]	-8	hSpCas9	negative selection	1098582
224294319	224294342	1	+	26627737	RPE1	viability after 9 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-5.018724930036141	[1736]	[28,0]	-9	hSpCas9	negative selection	1098585
224303803	224303826	1	-	26627737	RPE1	viability after 9 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-0.03505491906632474	[228]	[55,87]	0	hSpCas9	negative selection	1098586
224304800	224304823	1	-	26627737	RPE1	viability after 9 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-2.0646402673654682	[251]	[10,28]	-8	hSpCas9	negative selection	1098587
224308091	224308114	1	-	26627737	RPE1	viability after 9 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-1.3902948227101775	[1744]	[224,186]	-7	hSpCas9	negative selection	1098588
224330052	224330075	1	+	26627737	RPE1	viability after 9 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.5440171751521246	[468]	[69,24]	-8	hSpCas9	negative selection	1098589
224289483	224289506	1	-	26627737	RPE1	viability after 12 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-2.8149458283619375	[2598]	[140,54]	-9	hSpCas9	negative selection	1180897
224294319	224294342	1	+	26627737	RPE1	viability after 12 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-4.856002291583428	[1736]	[19,11]	-9	hSpCas9	negative selection	1180900
224303803	224303826	1	-	26627737	RPE1	viability after 12 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-3.100831839418001	[228]	[12,0]	-9	hSpCas9	negative selection	1180901
224304800	224304823	1	-	26627737	RPE1	viability after 12 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-0.5265796601491413	[251]	[12,82]	-4	hSpCas9	negative selection	1180902
224308091	224308114	1	-	26627737	RPE1	viability after 12 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-1.566252274665249	[1744]	[83,236]	-8	hSpCas9	negative selection	1180903
224330052	224330075	1	+	26627737	RPE1	viability after 12 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.6740738173989467	[468]	[38,39]	-8	hSpCas9	negative selection	1180904
224289483	224289506	1	-	26627737	RPE1	viability after 15 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-2.4775979252418527	[2598]	[131,131]	-8	hSpCas9	negative selection	1263212
224294319	224294342	1	+	26627737	RPE1	viability after 15 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-8.940633164838498	[1736]	[0,0]	-9	hSpCas9	negative selection	1263215
224303803	224303826	1	-	26627737	RPE1	viability after 15 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-0.5644916240070819	[228]	[82,5]	-4	hSpCas9	negative selection	1263216
224304800	224304823	1	-	26627737	RPE1	viability after 15 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.1820901529188041	[251]	[7,53]	-6	hSpCas9	negative selection	1263217
224308091	224308114	1	-	26627737	RPE1	viability after 15 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-0.8384660147574119	[1744]	[244,305]	-5	hSpCas9	negative selection	1263218
224330052	224330075	1	+	26627737	RPE1	viability after 15 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.7148302622124398	[468]	[16,62]	-8	hSpCas9	negative selection	1263219
224289483	224289506	1	-	26627737	RPE1	viability after 18 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-2.3710408258953253	[2598]	[137,132]	-8	hSpCas9	negative selection	1345527
224294319	224294342	1	+	26627737	RPE1	viability after 18 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-4.126971758995234	[1736]	[50,0]	-9	hSpCas9	negative selection	1345530
224303803	224303826	1	-	26627737	RPE1	viability after 18 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-1.522158134525109	[228]	[21,20]	-7	hSpCas9	negative selection	1345531
224304800	224304823	1	-	26627737	RPE1	viability after 18 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.379565681627614	[251]	[0,52]	-7	hSpCas9	negative selection	1345532
224308091	224308114	1	-	26627737	RPE1	viability after 18 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-0.907390954306458	[1744]	[121,388]	-5	hSpCas9	negative selection	1345533
224330052	224330075	1	+	26627737	RPE1	viability after 18 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-0.9758916711337704	[468]	[59,68]	-6	hSpCas9	negative selection	1345534
224289483	224289506	1	-	26627737	HeLa	viability after 8 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-0.8181156876810776	[900]	[360,119,216]	-7	hSpCas9	negative selection	1427842
224294319	224294342	1	+	26627737	HeLa	viability after 8 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-1.1241042657122498	[897]	[195,232,116]	-8	hSpCas9	negative selection	1427845
224303803	224303826	1	-	26627737	HeLa	viability after 8 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	0.739878545737817	[289]	[197,258,174]	6	hSpCas9	negative selection	1427846
224304800	224304823	1	-	26627737	HeLa	viability after 8 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.3068939808054625	[247]	[67,50,18]	-8	hSpCas9	negative selection	1427847
224308091	224308114	1	-	26627737	HeLa	viability after 8 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	0.11464795274961359	[509]	[320,301,123]	1	hSpCas9	negative selection	1427848
224330052	224330075	1	+	26627737	HeLa	viability after 8 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-0.8627879034485332	[228]	[68,50,47]	-7	hSpCas9	negative selection	1427849
224289483	224289506	1	-	26627737	HeLa	viability after 12 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-0.6571159745404467	[900]	[373,201,139]	-5	hSpCas9	negative selection	1510157
224294319	224294342	1	+	26627737	HeLa	viability after 12 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-2.853794397689956	[897]	[54,42,56]	-9	hSpCas9	negative selection	1510160
224303803	224303826	1	-	26627737	HeLa	viability after 12 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-0.23156794243794332	[289]	[135,37,139]	-2	hSpCas9	negative selection	1510161
224304800	224304823	1	-	26627737	HeLa	viability after 12 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-2.153129527743294	[247]	[5,28,32]	-9	hSpCas9	negative selection	1510162
224308091	224308114	1	-	26627737	HeLa	viability after 12 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-0.24606388995360598	[509]	[210,74,258]	-2	hSpCas9	negative selection	1510163
224330052	224330075	1	+	26627737	HeLa	viability after 12 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-0.10348505026940702	[228]	[60,101,98]	-1	hSpCas9	negative selection	1510164
224289483	224289506	1	-	26627737	HeLa	viability after 15 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-0.9690242821174679	[900]	[237,141,180]	-7	hSpCas9	negative selection	1592472
224294319	224294342	1	+	26627737	HeLa	viability after 15 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-2.7661080344521354	[897]	[34,29,99]	-9	hSpCas9	negative selection	1592475
224303803	224303826	1	-	26627737	HeLa	viability after 15 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	0.33358279944258024	[289]	[216,96,129]	3	hSpCas9	negative selection	1592476
224304800	224304823	1	-	26627737	HeLa	viability after 15 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-2.099704244852257	[247]	[17,25,26]	-9	hSpCas9	negative selection	1592477
224308091	224308114	1	-	26627737	HeLa	viability after 15 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-0.36049773250324296	[509]	[153,87,249]	-3	hSpCas9	negative selection	1592478
224330052	224330075	1	+	26627737	HeLa	viability after 15 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-0.8614902910432137	[228]	[86,44,18]	-6	hSpCas9	negative selection	1592479
224289483	224289506	1	-	26627737	HeLa	viability after 18 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-0.8895342016117838	[900]	[179,117,180]	-7	hSpCas9	negative selection	1674787
224294319	224294342	1	+	26627737	HeLa	viability after 18 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-2.79336600678678	[897]	[22,22,99]	-9	hSpCas9	negative selection	1674790
224303803	224303826	1	-	26627737	HeLa	viability after 18 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	0.37071670410454166	[289]	[154,77,129]	3	hSpCas9	negative selection	1674791
224304800	224304823	1	-	26627737	HeLa	viability after 18 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.9531307987519564	[247]	[14,23,26]	-9	hSpCas9	negative selection	1674792
224308091	224308114	1	-	26627737	HeLa	viability after 18 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-0.3781342201128206	[509]	[96,75,249]	-3	hSpCas9	negative selection	1674793
224330052	224330075	1	+	26627737	HeLa	viability after 18 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-0.9323412995660579	[228]	[52,37,18]	-7	hSpCas9	negative selection	1674794
224289483	224289506	1	-	26627737	HCT116	viability after 6 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	0.4367118801683394	[1593]	[489,255]	2	hSpCas9	negative selection	1757102
224294319	224294342	1	+	26627737	HCT116	viability after 6 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	0.39255617498101664	[764]	[260,100]	2	hSpCas9	negative selection	1757105
224303803	224303826	1	-	26627737	HCT116	viability after 6 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	3.899415736377387	[96]	[233,223]	9	hSpCas9	negative selection	1757106
224304800	224304823	1	-	26627737	HCT116	viability after 6 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.5091376552700426	[432]	[1,35]	-7	hSpCas9	negative selection	1757107
224308091	224308114	1	-	26627737	HCT116	viability after 6 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-1.2397244478474407	[1404]	[108,84]	-6	hSpCas9	negative selection	1757108
224330052	224330075	1	+	26627737	HCT116	viability after 6 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.6949545984143088	[737]	[98,0]	-7	hSpCas9	negative selection	1757109
224289483	224289506	1	-	26627737	HCT116	viability after 8 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.0956097341274496	[573]	[78,233,129]	-8	hSpCas9	negative selection	1839417
224294319	224294342	1	+	26627737	HCT116	viability after 8 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-1.6640192286680207	[519]	[124,66,79]	-9	hSpCas9	negative selection	1839420
224303803	224303826	1	-	26627737	HCT116	viability after 8 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	1.3200141838204726	[109]	[158,132,161]	9	hSpCas9	negative selection	1839421
224304800	224304823	1	-	26627737	HCT116	viability after 8 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.5604300107842777	[137]	[20,8,46]	-9	hSpCas9	negative selection	1839422
224308091	224308114	1	-	26627737	HCT116	viability after 8 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-0.8587422505318381	[589]	[141,202,191]	-8	hSpCas9	negative selection	1839423
224330052	224330075	1	+	26627737	HCT116	viability after 8 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-2.097316135589932	[497]	[101,21,68]	-9	hSpCas9	negative selection	1839424
224289483	224289506	1	-	26627737	HCT116	viability after 9 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-2.299193567052319	[1593]	[38,123]	-9	hSpCas9	negative selection	1921732
224294319	224294342	1	+	26627737	HCT116	viability after 9 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-1.8819022046148248	[764]	[79,35]	-8	hSpCas9	negative selection	1921735
224303803	224303826	1	-	26627737	HCT116	viability after 9 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	0.4775270032037735	[96]	[44,28]	3	hSpCas9	negative selection	1921736
224304800	224304823	1	-	26627737	HCT116	viability after 9 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.9087125880472233	[432]	[27,32]	-8	hSpCas9	negative selection	1921737
224308091	224308114	1	-	26627737	HCT116	viability after 9 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-1.904522138698803	[1404]	[102,97]	-8	hSpCas9	negative selection	1921738
224330052	224330075	1	+	26627737	HCT116	viability after 9 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.9703366519909657	[737]	[37,59]	-8	hSpCas9	negative selection	1921739
224289483	224289506	1	-	26627737	HCT116	viability after 12 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-0.728991905225236	[573]	[159,267,121]	-7	hSpCas9	negative selection	2004047
224294319	224294342	1	+	26627737	HCT116	viability after 12 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-4.723056703771487	[519]	[20,5,2]	-9	hSpCas9	negative selection	2004050
224303803	224303826	1	-	26627737	HCT116	viability after 12 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	1.0128140799192256	[109]	[87,138,125]	8	hSpCas9	negative selection	2004051
224304800	224304823	1	-	26627737	HCT116	viability after 12 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.5679516605945647	[137]	[23,6,41]	-9	hSpCas9	negative selection	2004052
224308091	224308114	1	-	26627737	HCT116	viability after 12 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-1.0920433806982868	[589]	[127,232,78]	-8	hSpCas9	negative selection	2004053
224330052	224330075	1	+	26627737	HCT116	viability after 12 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-2.1178642415527285	[497]	[96,32,46]	-9	hSpCas9	negative selection	2004054
224289483	224289506	1	-	26627737	HCT116	viability after 15 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.0985736176643124	[573]	[62,254,132]	-8	hSpCas9	negative selection	2086362
224294319	224294342	1	+	26627737	HCT116	viability after 15 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-3.5978180227779264	[519]	[56,1,18]	-9	hSpCas9	negative selection	2086365
224303803	224303826	1	-	26627737	HCT116	viability after 15 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	0.7266876366075853	[109]	[102,152,57]	6	hSpCas9	negative selection	2086366
224304800	224304823	1	-	26627737	HCT116	viability after 15 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.6453734604890422	[137]	[34,1,39]	-9	hSpCas9	negative selection	2086367
224308091	224308114	1	-	26627737	HCT116	viability after 15 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-1.2088457518727025	[589]	[123,248,64]	-8	hSpCas9	negative selection	2086368
224330052	224330075	1	+	26627737	HCT116	viability after 15 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.7842363985105612	[497]	[131,34,87]	-9	hSpCas9	negative selection	2086369
224289483	224289506	1	-	26627737	HCT116	viability after 18 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.19236735626396	[573]	[42,138,183]	-8	hSpCas9	negative selection	2168677
224294319	224294342	1	+	26627737	HCT116	viability after 18 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-2.7256978112781267	[519]	[76,4,33]	-9	hSpCas9	negative selection	2168680
224303803	224303826	1	-	26627737	HCT116	viability after 18 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	0.4915733494023923	[109]	[32,85,105]	4	hSpCas9	negative selection	2168681
224304800	224304823	1	-	26627737	HCT116	viability after 18 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-2.119789518057007	[137]	[26,10,7]	-9	hSpCas9	negative selection	2168682
224308091	224308114	1	-	26627737	HCT116	viability after 18 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-1.3242399451187996	[589]	[83,200,47]	-8	hSpCas9	negative selection	2168683
224330052	224330075	1	+	26627737	HCT116	viability after 18 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.609504220494871	[497]	[70,70,95]	-8	hSpCas9	negative selection	2168684
224303769	224303792	1	+	24336569	HL60	viability	CCATGAAGGAGAACTCCACGAGG	NVL	ENSG00000143748	-1.1325973201295036	[1320]	[1274]	-8	hSpCas9	negative selection	2281903
224303802	224303825	1	+	24336569	HL60	viability	CCCAGGTGGTGGTACACCTCCGG	NVL	ENSG00000143748	0.3487082586474978	[402]	[1085]	3	hSpCas9	negative selection	2281904
224303818	224303841	1	-	24336569	HL60	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-0.835811773023339	[500]	[593]	-6	hSpCas9	negative selection	2281905
224304755	224304778	1	-	24336569	HL60	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-1.392956742849948	[550]	[443]	-8	hSpCas9	negative selection	2281906
224304760	224304783	1	+	24336569	HL60	viability	CACATCTTCAAACTTCACGTTGG	NVL	ENSG00000143748	-1.2459998726407868	[166]	[148]	-8	hSpCas9	negative selection	2281907
224304768	224304791	1	+	24336569	HL60	viability	CAAACTTCACGTTGGAGATCTGG	NVL	ENSG00000143748	0.5042788680803982	[615]	[1848]	4	hSpCas9	negative selection	2281908
224304801	224304824	1	-	24336569	HL60	viability	TTGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	0.01343223936858784	[352]	[753]	0	hSpCas9	negative selection	2281909
224305063	224305086	1	-	24336569	HL60	viability	GAAGATCTTCAGGAAGTAGATGG	NVL	ENSG00000143748	-1.3145970207488282	[381]	[324]	-8	hSpCas9	negative selection	2281910
224305073	224305096	1	-	24336569	HL60	viability	AAGGAAGAAAGAAGATCTTCAGG	NVL	ENSG00000143748	0.8499009960450141	[225]	[861]	7	hSpCas9	negative selection	2281911
224305120	224305143	1	-	24336569	HL60	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	0.826417697382672	[96]	[363]	6	hSpCas9	negative selection	2281912
224303769	224303792	1	+	24336569	KBM7	viability	CCATGAAGGAGAACTCCACGAGG	NVL	ENSG00000143748	-4.092313917787408	[1231]	[196]	-9	hSpCas9	negative selection	2349080
224303802	224303825	1	+	24336569	KBM7	viability	CCCAGGTGGTGGTACACCTCCGG	NVL	ENSG00000143748	-0.6754241739203765	[242]	[414]	-5	hSpCas9	negative selection	2349081
224303818	224303841	1	-	24336569	KBM7	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-4.254934118606486	[405]	[57]	-9	hSpCas9	negative selection	2349082
224304755	224304778	1	-	24336569	KBM7	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-2.2011754652592095	[348]	[206]	-8	hSpCas9	negative selection	2349083
224304760	224304783	1	+	24336569	KBM7	viability	CACATCTTCAAACTTCACGTTGG	NVL	ENSG00000143748	-2.74713947840779	[159]	[64]	-9	hSpCas9	negative selection	2349084
224304768	224304791	1	+	24336569	KBM7	viability	CAAACTTCACGTTGGAGATCTGG	NVL	ENSG00000143748	0.3655158990264864	[429]	[1510]	3	hSpCas9	negative selection	2349085
224304801	224304824	1	-	24336569	KBM7	viability	TTGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-2.6224534139629285	[437]	[193]	-9	hSpCas9	negative selection	2349086
224305063	224305086	1	-	24336569	KBM7	viability	GAAGATCTTCAGGAAGTAGATGG	NVL	ENSG00000143748	-0.8083736510437391	[347]	[541]	-6	hSpCas9	negative selection	2349087
224305073	224305096	1	-	24336569	KBM7	viability	AAGGAAGAAAGAAGATCTTCAGG	NVL	ENSG00000143748	0.13585583442567992	[314]	[943]	1	hSpCas9	negative selection	2349088
224305120	224305143	1	-	24336569	KBM7	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.5024150626289826	[428]	[825]	-4	hSpCas9	negative selection	2349089
224254910	224254933	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTCGCCAGGCTGGAGTACAGTGG	NVL	ENSG00000143748	0.42704561705979716	[5,14]	[1,3]	2	dCas9-VP64	positive selection	2412491
224232608	224232631	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAAGCTGCGG	NVL	ENSG00000143748	4.479776146187553	[3,10]	[5,71]	9	dCas9-VP64	positive selection	2414979
224305649	224305672	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATTGTTTGAACCTAG	NVL	ENSG00000143748	0.964443282063522	[91,283]	[89,70]	4	dCas9-VP64	positive selection	2426637
224330257	224330280	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TACTTTTATTCTGACGGAAACGG	NVL	ENSG00000143748	-2.0343674092699873	[80,895]	[18,33]	-9	dCas9-VP64	positive selection	2430607
224330363	224330386	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTCCAGGGTCCACTGGGCAGG	NVL	ENSG00000143748	1.25936492000359	[167,154]	[13,160]	5	dCas9-VP64	positive selection	2430608
224330340	224330363	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTCTAGGGGCCTTATTTTGCAGG	NVL	ENSG00000143748	-2.1429145730046066	[286,4]	[11,0]	-9	dCas9-VP64	positive selection	2430609
224253498	224253521	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGAGGCGGGAGGATCACAAGG	NVL	ENSG00000143748	3.278703021819371	[41,15]	[74,47]	8	dCas9-VP64	positive selection	2449181
224291278	224291301	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCGCAACCTCCGCCTCCCAG	NVL	ENSG00000143748	-0.9705266312095737	[543,439]	[39,70]	-6	dCas9-VP64	positive selection	2469143
224254910	224254933	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTCGCCAGGCTGGAGTACAGTGG	NVL	ENSG00000143748	0.7866946329190116	[53,86]	[29,47]	5	dCas9-VP64	positive selection	2507746
224232608	224232631	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAAGCTGCGG	NVL	ENSG00000143748	1.4055177615841226	[19,51]	[4,54]	7	dCas9-VP64	positive selection	2510234
224305649	224305672	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATTGTTTGAACCTAG	NVL	ENSG00000143748	-0.320288383300443	[193,176]	[58,37]	-3	dCas9-VP64	positive selection	2521892
224330257	224330280	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TACTTTTATTCTGACGGAAACGG	NVL	ENSG00000143748	-0.261551751776394	[141,109]	[33,33]	-2	dCas9-VP64	positive selection	2525862
224330363	224330386	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTCCAGGGTCCACTGGGCAGG	NVL	ENSG00000143748	-0.5462606668475979	[80,164]	[44,9]	-5	dCas9-VP64	positive selection	2525863
224330340	224330363	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTCTAGGGGCCTTATTTTGCAGG	NVL	ENSG00000143748	-0.24967316152726304	[82,97]	[26,21]	-2	dCas9-VP64	positive selection	2525864
224253498	224253521	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGAGGCGGGAGGATCACAAGG	NVL	ENSG00000143748	0.5394300049106193	[35,34]	[25,7]	4	dCas9-VP64	positive selection	2544436
224291278	224291301	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCGCAACCTCCGCCTCCCAG	NVL	ENSG00000143748	0.25678800348412345	[582,649]	[296,187]	2	dCas9-VP64	positive selection	2564398
224236504	224236527	1	+	27013184	SW480	treatment with recombinant TRAIL	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-1.6063920367998312	[4,24]	[1,1]	-6	hSpCas9	positive selection	2961437
224236545	224236568	1	+	27013184	SW480	treatment with recombinant TRAIL	AAATTTACATCTGCATCCAGTGG	NVL	ENSG00000143748	0.6305202964956236	[35,74]	[44,22]	3	hSpCas9	positive selection	2961438
224236548	224236571	1	+	27013184	SW480	treatment with recombinant TRAIL	TTTACATCTGCATCCAGTGGTGG	NVL	ENSG00000143748	1.14857203431249	[129,170]	[114,180]	5	hSpCas9	positive selection	2961439
224236553	224236576	1	+	27013184	SW480	treatment with recombinant TRAIL	ATCTGCATCCAGTGGTGGTTTGG	NVL	ENSG00000143748	-0.15833790698982586	[284,388]	[156,87]	0	hSpCas9	positive selection	2961440
224227610	224227633	1	-	27013184	SW480	treatment with recombinant TRAIL	CCGGTGATGTCTCCAGCAGCCGG	NVL	ENSG00000143748	1.1455753085740135	[101,166]	[45,238]	5	hSpCas9	positive selection	2961441
224227643	224227666	1	-	27013184	SW480	treatment with recombinant TRAIL	AATCATGTATGAACGTTTGCAGG	NVL	ENSG00000143748	-0.4936175790811772	[213,100]	[55,40]	-2	hSpCas9	positive selection	2961442
224236561	224236584	1	-	27013184	SW480	treatment with recombinant TRAIL	GAATGGTACCAAACCACCACTGG	NVL	ENSG00000143748	-3.4204194948920277	[55,41]	[1,1]	-9	hSpCas9	positive selection	2961443
224305025	224305048	1	+	27013184	SW480	treatment with recombinant TRAIL	ACACCTTACCTTTCTTTTGCAGG	NVL	ENSG00000143748	0.8511565039938402	[620,703]	[575,422]	4	hSpCas9	positive selection	2961444
224311783	224311806	1	+	27013184	SW480	treatment with recombinant TRAIL	CTAAATGTTTGGCTTACCTGTGG	NVL	ENSG00000143748	-4.622218741100794	[130,93]	[1,1]	-9	hSpCas9	positive selection	2961445
224311847	224311870	1	+	27013184	SW480	treatment with recombinant TRAIL	TTTCAGTATACCTCAGTAAAAGG	NVL	ENSG00000143748	1.1014818085787401	[11,75]	[14,70]	5	hSpCas9	positive selection	2961446
224311850	224311873	1	+	27013184	SW480	treatment with recombinant TRAIL	CAGTATACCTCAGTAAAAGGAGG	NVL	ENSG00000143748	-1.7479893978202745	[31,15]	[3,1]	-7	hSpCas9	positive selection	2961447
224311851	224311874	1	+	27013184	SW480	treatment with recombinant TRAIL	AGTATACCTCAGTAAAAGGAGGG	NVL	ENSG00000143748	2.751845790309389	[11,3]	[1,55]	9	hSpCas9	positive selection	2961448
224326435	224326458	1	+	27013184	SW480	treatment with recombinant TRAIL	ATATTTGCCACATTTGTTACTGG	NVL	ENSG00000143748	1.5864155532037838	[383,260]	[372,498]	7	hSpCas9	positive selection	2961449
224317673	224317696	1	-	27013184	SW480	treatment with recombinant TRAIL	GAGTAAGTATACCAAATGCAGGG	NVL	ENSG00000143748	0.5413060846056064	[242,202]	[44,277]	2	hSpCas9	positive selection	2961450
224317674	224317697	1	-	27013184	SW480	treatment with recombinant TRAIL	TGAGTAAGTATACCAAATGCAGG	NVL	ENSG00000143748	-1.6228276718932144	[119,152]	[1,42]	-6	hSpCas9	positive selection	2961451
224326390	224326413	1	-	27013184	SW480	treatment with recombinant TRAIL	CTGATTTACAAAGAGTGTACAGG	NVL	ENSG00000143748	1.9228117098818083	[49,21]	[62,57]	8	hSpCas9	positive selection	2961452
224326442	224326465	1	-	27013184	SW480	treatment with recombinant TRAIL	TACCTTACCAGTAACAAATGTGG	NVL	ENSG00000143748	1.3732241093726976	[19,94]	[48,76]	6	hSpCas9	positive selection	2961453
224326440	224326463	1	+	27013184	SW480	treatment with recombinant TRAIL	TGCCACATTTGTTACTGGTAAGG	NVL	ENSG00000143748	2.3493244357638017	[534,1036]	[1756,1568]	8	hSpCas9	positive selection	2961454
224305028	224305051	1	-	27013184	SW480	treatment with recombinant TRAIL	TGTCCTGCAAAAGAAAGGTAAGG	NVL	ENSG00000143748	0.4842118425675521	[238,266]	[191,94]	2	hSpCas9	positive selection	2961455
224305033	224305056	1	-	27013184	SW480	treatment with recombinant TRAIL	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.7106688387134079	[73,69]	[30,1]	-3	hSpCas9	positive selection	2961456
224227610	224227633	1	+	27013184	SW480	treatment with recombinant TRAIL	CCGGCTGCTGGAGACATCACCGG	NVL	ENSG00000143748	-2.690020952775077	[441,876]	[22,70]	-8	hSpCas9	positive selection	2961457
224330052	224330075	1	+	27013184	SW480	treatment with recombinant TRAIL	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	1.3010405603842345	[16,1]	[16,1]	6	hSpCas9	positive selection	2961458
224311779	224311802	1	-	27013184	SW480	treatment with recombinant TRAIL	AGGTAAGCCAAACATTTAGTGGG	NVL	ENSG00000143748	-3.041249191582582	[285,282]	[23,1]	-8	hSpCas9	positive selection	2961459
224311780	224311803	1	-	27013184	SW480	treatment with recombinant TRAIL	CAGGTAAGCCAAACATTTAGTGG	NVL	ENSG00000143748	-1.4334936627031207	[421,304]	[22,109]	-6	hSpCas9	positive selection	2961460
224227616	224227639	1	+	27013184	SW480	treatment with recombinant TRAIL	GCTGGAGACATCACCGGCTGAGG	NVL	ENSG00000143748	-2.7093589494896917	[54,41]	[1,4]	-8	hSpCas9	positive selection	2961461
224330093	224330116	1	+	27013184	SW480	treatment with recombinant TRAIL	TTATTATCCACGAACCCTGCAGG	NVL	ENSG00000143748	0.9163938434504315	[1,2]	[1,1]	4	hSpCas9	positive selection	2961462
224227617	224227640	1	+	27013184	SW480	treatment with recombinant TRAIL	CTGGAGACATCACCGGCTGAGGG	NVL	ENSG00000143748	-1.9591497444996129	[430,530]	[23,93]	-7	hSpCas9	positive selection	2961463
224330098	224330121	1	+	27013184	SW480	treatment with recombinant TRAIL	ATCCACGAACCCTGCAGGTCTGG	NVL	ENSG00000143748	2.4230062236594363	[103,40]	[191,148]	8	hSpCas9	positive selection	2961464
224227656	224227679	1	+	27013184	SW480	treatment with recombinant TRAIL	ATACATGATTTGATCCTGAAAGG	NVL	ENSG00000143748	0.2516070115705382	[31,22]	[22,1]	1	hSpCas9	positive selection	2961465
224330099	224330122	1	+	27013184	SW480	treatment with recombinant TRAIL	TCCACGAACCCTGCAGGTCTGGG	NVL	ENSG00000143748	-0.9994428814518916	[144,181]	[36,31]	-4	hSpCas9	positive selection	2961466
224303771	224303794	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-0.7196942773180066	[1,1]	[0,0]	-8	hSpCas9	positive selection	3007050
224289519	224289542	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCATCTAAAGGAGTCCAGGAGG	NVL	ENSG00000143748	0.8250786338659181	[1,2]	[2,4]	9	hSpCas9	positive selection	3007051
224304799	224304822	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTTACCAGCTAAAGCCAGGGGG	NVL	ENSG00000143748	-1.2652103893628186	[2,2]	[0,0]	-9	hSpCas9	positive selection	3007052
224289618	224289641	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTCATGGCACTGTGCCGAGAGG	NVL	ENSG00000143748	0.22384584776409366	[0,0]	[0,0]	5	hSpCas9	positive selection	3007053
224303771	224303794	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-0.12213000317348977	[1,1]	[1,0]	-2	hSpCas9	positive selection	3074908
224289519	224289542	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCATCTAAAGGAGTCCAGGAGG	NVL	ENSG00000143748	-0.08272335864212077	[1,1]	[1,0]	-1	hSpCas9	positive selection	3074909
224304799	224304822	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTTACCAGCTAAAGCCAGGGGG	NVL	ENSG00000143748	0.5496743845092162	[2,2]	[4,2]	8	hSpCas9	positive selection	3074910
224289618	224289641	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTCATGGCACTGTGCCGAGAGG	NVL	ENSG00000143748	0.4833744715089985	[0,0]	[0,0]	8	hSpCas9	positive selection	3074911
224305073	224305096		-	24336571	A375	resistance to PLX after 7 days	AAGGAAGAAAGAAGATCTTCAGG	NVL	ENSG00000143748	0.010244192449762227	[13,12]	[13,12]	0	hSpCas9	positive selection	3132131
224305025	224305048		+	24336571	A375	resistance to PLX after 7 days	ACACCTTACCTTTCTTTTGCAGG	NVL	ENSG00000143748	-0.20457331434110992	[39,51]	[39,39]	-6	hSpCas9	positive selection	3132132
224303784	224303807		-	24336571	A375	resistance to PLX after 7 days	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.050769475288275245	[78,78]	[81,81]	1	hSpCas9	positive selection	3132133
224305033	224305056		-	24336571	A375	resistance to PLX after 7 days	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	0.1479775257822461	[10,13]	[14,12]	5	hSpCas9	positive selection	3132134
224305120	224305143		-	24336571	A375	resistance to PLX after 7 days	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	0.31309035119930173	[3,4]	[4,4]	8	hSpCas9	positive selection	3132135
224303821	224303844		-	24336571	A375	resistance to PLX after 7 days	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	0.14160934674175318	[31,28]	[30,35]	4	hSpCas9	positive selection	3132136
224303760	224303783		-	24336571	A375	resistance to PLX after 7 days	GTTCTCCTTCATGGACCACCAGG	NVL	ENSG00000143748	0.1901668089365509	[44,36]	[48,44]	6	hSpCas9	positive selection	3132138
224305073	224305096		-	24336571	A375	resistance to PLX after 14 days	AAGGAAGAAAGAAGATCTTCAGG	NVL	ENSG00000143748	0.1397276715870996	[8,12]	[4,4]	1	hSpCas9	positive selection	3189924
224305025	224305048		+	24336571	A375	resistance to PLX after 14 days	ACACCTTACCTTTCTTTTGCAGG	NVL	ENSG00000143748	-0.7434504537135733	[39,57]	[12,12]	-8	hSpCas9	positive selection	3189925
224303784	224303807		-	24336571	A375	resistance to PLX after 14 days	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	-0.1976363470631184	[80,93]	[34,35]	-2	hSpCas9	positive selection	3189926
224305033	224305056		-	24336571	A375	resistance to PLX after 14 days	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.08386821691002821	[9,7]	[2,3]	-1	hSpCas9	positive selection	3189927
224305120	224305143		-	24336571	A375	resistance to PLX after 14 days	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	0.49456339443089314	[1,4]	[1,1]	4	hSpCas9	positive selection	3189928
224303821	224303844		-	24336571	A375	resistance to PLX after 14 days	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.584531538082862	[20,25]	[6,6]	-7	hSpCas9	positive selection	3189929
224303760	224303783		-	24336571	A375	resistance to PLX after 14 days	GTTCTCCTTCATGGACCACCAGG	NVL	ENSG00000143748	0.2842516344814259	[39,31]	[18,21]	3	hSpCas9	positive selection	3189931
224305073	224305096		-	24336571	A375	viability after 7 days	AAGGAAGAAAGAAGATCTTCAGG	NVL	ENSG00000143748	-0.1626416028492784	[15]	[13,12]	-2	hSpCas9	negative selection	3247717
224305025	224305048		+	24336571	A375	viability after 7 days	ACACCTTACCTTTCTTTTGCAGG	NVL	ENSG00000143748	-0.3351905761673226	[60]	[39,51]	-5	hSpCas9	negative selection	3247718
224303784	224303807		-	24336571	A375	viability after 7 days	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.7652142920395721	[48]	[78,78]	9	hSpCas9	negative selection	3247719
224305033	224305056		-	24336571	A375	viability after 7 days	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.9340618511518978	[25]	[10,13]	-8	hSpCas9	negative selection	3247720
224305120	224305143		-	24336571	A375	viability after 7 days	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.16807007278404695	[4]	[3,4]	-2	hSpCas9	negative selection	3247721
224303821	224303844		-	24336571	A375	viability after 7 days	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-1.156732108234468	[71]	[31,28]	-9	hSpCas9	negative selection	3247722
224303760	224303783		-	24336571	A375	viability after 7 days	GTTCTCCTTCATGGACCACCAGG	NVL	ENSG00000143748	-0.45831749400354505	[59]	[44,36]	-6	hSpCas9	negative selection	3247724
224305073	224305096		-	24336571	A375	viability after 14 days	AAGGAAGAAAGAAGATCTTCAGG	NVL	ENSG00000143748	-0.43541103446923224	[15]	[8,12]	-5	hSpCas9	negative selection	3305510
224305025	224305048		+	24336571	A375	viability after 14 days	ACACCTTACCTTTCTTTTGCAGG	NVL	ENSG00000143748	-0.23487037357101492	[60]	[39,57]	-3	hSpCas9	negative selection	3305511
224303784	224303807		-	24336571	A375	viability after 14 days	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.9242110836995627	[48]	[80,93]	9	hSpCas9	negative selection	3305512
224305033	224305056		-	24336571	A375	viability after 14 days	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.4050642596162795	[25]	[9,7]	-9	hSpCas9	negative selection	3305513
224305120	224305143		-	24336571	A375	viability after 14 days	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.33571517366876646	[4]	[1,4]	-4	hSpCas9	negative selection	3305514
224303821	224303844		-	24336571	A375	viability after 14 days	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-1.5348753515511122	[71]	[20,25]	-9	hSpCas9	negative selection	3305515
224303760	224303783		-	24336571	A375	viability after 14 days	GTTCTCCTTCATGGACCACCAGG	NVL	ENSG00000143748	-0.6441817527984648	[59]	[39,31]	-7	hSpCas9	negative selection	3305517
224305120	224305143	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	9.714909405690763	[70,70]	[389,389]	9	hSpCas9	positive selection	3382780
224305033	224305056	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	1.672363710724679	[47,47]	[0,0]	6	hSpCas9	positive selection	3382781
224300561	224300584	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	2.0478728458168853	[36,36]	[0,0]	7	hSpCas9	positive selection	3382782
224303770	224303793	1	+	26780180	HT29	viability (Avana library 4 designs)	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	4.91931787113161	[]	[]	9	hSpCas9	negative selection	3444952
224289519	224289542	1	-	26780180	HT29	viability (Avana library 4 designs)	GCCATCTAAAGGAGTCCAGGAGG	NVL	ENSG00000143748	3.04398584667878	[]	[]	8	hSpCas9	negative selection	3444953
224304799	224304822	1	-	26780180	HT29	viability (Avana library 4 designs)	GTTTACCAGCTAAAGCCAGGGGG	NVL	ENSG00000143748	4.38453926387365	[]	[]	9	hSpCas9	negative selection	3444954
224289618	224289641	1	-	26780180	HT29	viability (Avana library 4 designs)	TCTCATGGCACTGTGCCGAGAGG	NVL	ENSG00000143748	0.297265543443517	[]	[]	1	hSpCas9	negative selection	3444955
224304799	224304822	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTTACCAGCTAAAGCCAGGGGG	NVL	ENSG00000143748	-11.8278200567451	[]	[]	-8	hSpCas9	negative selection	3537434
224289618	224289641	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCATGGCACTGTGCCGAGAGG	NVL	ENSG00000143748	-2.22850891164163	[]	[]	-3	hSpCas9	negative selection	3537435
224303770	224303793	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-12.1935685537199	[]	[]	-8	hSpCas9	negative selection	3537436
224289519	224289542	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCATCTAAAGGAGTCCAGGAGG	NVL	ENSG00000143748	-6.48304195011685	[]	[]	-6	hSpCas9	negative selection	3537437
224304760	224304783	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CACATCTTCAAACTTCACGTTGG	NVL	ENSG00000143748	-22.7321924281552	[]	[]	-9	hSpCas9	negative selection	3537438
224304801	224304824	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-4.36118847184452	[]	[]	-5	hSpCas9	negative selection	3537439
224304799	224304822	1	-	26780180	A375	viability (Avana lentiGuide)	GTTTACCAGCTAAAGCCAGGGGG	NVL	ENSG00000143748	10.7675923414082	[]	[]	7	hSpCas9	negative selection	3646093
224289618	224289641	1	-	26780180	A375	viability (Avana lentiGuide)	TCTCATGGCACTGTGCCGAGAGG	NVL	ENSG00000143748	2.49889639364301	[]	[]	2	hSpCas9	negative selection	3646094
224303770	224303793	1	+	26780180	A375	viability (Avana lentiGuide)	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	25.8271833805511	[]	[]	9	hSpCas9	negative selection	3646095
224289519	224289542	1	-	26780180	A375	viability (Avana lentiGuide)	GCCATCTAAAGGAGTCCAGGAGG	NVL	ENSG00000143748	12.9169340316758	[]	[]	7	hSpCas9	negative selection	3646096
224304760	224304783	1	+	26780180	A375	viability (Avana lentiGuide)	CACATCTTCAAACTTCACGTTGG	NVL	ENSG00000143748	22.7833795077895	[]	[]	9	hSpCas9	negative selection	3646097
224304801	224304824	1	-	26780180	A375	viability (Avana lentiGuide)	TTGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	11.2947596123834	[]	[]	7	hSpCas9	negative selection	3646098
224304799	224304822	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTTACCAGCTAAAGCCAGGGGG	NVL	ENSG00000143748	-0.9245172465595263	[4]	[3,0]	-8	hSpCas9	positive selection	3754752
224289618	224289641	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCATGGCACTGTGCCGAGAGG	NVL	ENSG00000143748	-0.6117585483310499	[0]	[0,0]	-7	hSpCas9	positive selection	3754753
224303770	224303793	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-1.5810995859330141	[3]	[0,0]	-9	hSpCas9	positive selection	3754754
224289519	224289542	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCATCTAAAGGAGTCCAGGAGG	NVL	ENSG00000143748	-1.4346180004716478	[4]	[1,0]	-9	hSpCas9	positive selection	3754755
224304760	224304783	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACATCTTCAAACTTCACGTTGG	NVL	ENSG00000143748	-1.664185321259806	[5]	[0,1]	-9	hSpCas9	positive selection	3754756
224304801	224304824	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-0.48266443902784323	[5]	[4,2]	-6	hSpCas9	positive selection	3754757
224304799	224304822	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTTACCAGCTAAAGCCAGGGGG	NVL	ENSG00000143748	-0.5848547604172782	[5]	[1,3]	-6	hSpCas9	positive selection	3863359
224289618	224289641	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCATGGCACTGTGCCGAGAGG	NVL	ENSG00000143748	-0.22679587621736363	[0]	[0,0]	-3	hSpCas9	positive selection	3863360
224303770	224303793	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-2.079076726009326	[4]	[0,0]	-9	hSpCas9	positive selection	3863361
224289519	224289542	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCATCTAAAGGAGTCCAGGAGG	NVL	ENSG00000143748	-0.7336435902577626	[4]	[2,1]	-7	hSpCas9	positive selection	3863362
224304760	224304783	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACATCTTCAAACTTCACGTTGG	NVL	ENSG00000143748	-0.9435870973126851	[6]	[2,2]	-8	hSpCas9	positive selection	3863363
224304801	224304824	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-1.5454189695576972	[5]	[0,1]	-9	hSpCas9	positive selection	3863364
224300561	224300584	1	-	26780180	A375	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	1.72578044918569	[]	[]	9	hSpCas9	negative selection	3974558
224303784	224303807	1	-	26780180	A375	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	-0.216499682267211	[]	[]	-6	hSpCas9	negative selection	3974559
224305033	224305056	1	-	26780180	A375	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	1.06269447643894	[]	[]	5	hSpCas9	negative selection	3974560
224305120	224305143	1	-	26780180	A375	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	1.66853073885785	[]	[]	9	hSpCas9	negative selection	3974561
224300605	224300628	1	-	26780180	A375	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	2.80761427586641	[]	[]	9	hSpCas9	negative selection	3974562
224303821	224303844	1	-	26780180	A375	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	2.37018459522049	[]	[]	9	hSpCas9	negative selection	3974563
224300561	224300584	1	-	26780180	HT29	viability (GeCKOv2 library)	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	2.63788812642203	[]	[]	9	hSpCas9	negative selection	4082524
224303784	224303807	1	-	26780180	HT29	viability (GeCKOv2 library)	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	-0.0251406567107037	[]	[]	0	hSpCas9	negative selection	4082525
224305033	224305056	1	-	26780180	HT29	viability (GeCKOv2 library)	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	1.89525510399663	[]	[]	9	hSpCas9	negative selection	4082526
224305120	224305143	1	-	26780180	HT29	viability (GeCKOv2 library)	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	1.96651762813456	[]	[]	9	hSpCas9	negative selection	4082527
224300605	224300628	1	-	26780180	HT29	viability (GeCKOv2 library)	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	2.08678426121473	[]	[]	9	hSpCas9	negative selection	4082528
224303821	224303844	1	-	26780180	HT29	viability (GeCKOv2 library)	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	2.92667082516021	[]	[]	9	hSpCas9	negative selection	4082529
224305073	224305096	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGGAAGAAAGAAGATCTTCAGG	NVL	ENSG00000143748	-0.18940318703799905	[4]	[2,2]	-4	hSpCas9	positive selection	4156878
224305025	224305048	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACACCTTACCTTTCTTTTGCAGG	NVL	ENSG00000143748	0.06064327290364746	[5]	[3,3]	1	hSpCas9	positive selection	4156879
224303784	224303807	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.20847351332808406	[6]	[4,5]	5	hSpCas9	positive selection	4156880
224305033	224305056	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.3860935850941405	[4]	[2,1]	-7	hSpCas9	positive selection	4156881
224305120	224305143	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.2763637342024663	[1]	[0,0]	-6	hSpCas9	positive selection	4156882
224303821	224303844	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.17111991467305881	[5]	[3,2]	-4	hSpCas9	positive selection	4156883
224303760	224303783	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTCTCCTTCATGGACCACCAGG	NVL	ENSG00000143748	0.03470727665322171	[5]	[3,4]	0	hSpCas9	positive selection	4156885
224305073	224305096	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGGAAGAAAGAAGATCTTCAGG	NVL	ENSG00000143748	0.7378085884682949	[4]	[2,2,3,2]	5	hSpCas9	positive selection	4220900
224305025	224305048	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACACCTTACCTTTCTTTTGCAGG	NVL	ENSG00000143748	1.0763360620394755	[6]	[6,5,5,5]	7	hSpCas9	positive selection	4220901
224303784	224303807	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	1.1073766750134535	[6]	[5,6,5,5]	8	hSpCas9	positive selection	4220902
224305033	224305056	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	0.44071056580815143	[4]	[0,0,1,4]	3	hSpCas9	positive selection	4220903
224305120	224305143	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.25227932280258747	[1]	[0,0,0,0]	-4	hSpCas9	positive selection	4220904
224303821	224303844	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.6066678957271412	[5]	[0,1,3,0]	-8	hSpCas9	positive selection	4220905
224303760	224303783	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTCTCCTTCATGGACCACCAGG	NVL	ENSG00000143748	0.1382194165005643	[5]	[2,0,0,3]	1	hSpCas9	positive selection	4220907
224303821	224303844	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.9727073744965002	[3]	[0,1]	-9	hSpCas9	positive selection	4286774
224303784	224303807	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.42230106175811616	[3]	[4,3]	8	hSpCas9	positive selection	4286775
224300605	224300628	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-1.013933558474306	[4]	[1,0]	-9	hSpCas9	positive selection	4286776
224305120	224305143	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.17020525525916516	[2]	[1,1]	-3	hSpCas9	positive selection	4351032
224305033	224305056	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.035520253351910724	[1]	[1,0]	0	hSpCas9	positive selection	4351033
224300561	224300584	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.8140425038146201	[2]	[0,0]	-9	hSpCas9	positive selection	4351034
224294320	224294342	1	+	27760321	OCIAML3	viability	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-1.459672732388665	[550,449]	[138,144]	-8	hSpCas9	negative selection	4424182
224296491	224296513	1	+	27760321	OCIAML3	viability	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-2.6403718524490896	[265,230]	[34,25]	-9	hSpCas9	negative selection	4424183
224300636	224300658	1	-	27760321	OCIAML3	viability	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	0.5877075565083429	[155,149]	[180,178]	7	hSpCas9	negative selection	4424184
224303818	224303840	1	-	27760321	OCIAML3	viability	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-0.6811056628306048	[1108,917]	[456,537]	-6	hSpCas9	negative selection	4424185
224304801	224304823	1	-	27760321	OCIAML3	viability	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-0.7906524540089123	[257,256]	[88,152]	-6	hSpCas9	negative selection	4424186
224294320	224294342	1	+	27760321	OCIAML2	viability	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-1.451378280983792	[550,449]	[142,152]	-8	hSpCas9	negative selection	4507645
224296491	224296513	1	+	27760321	OCIAML2	viability	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-1.3519909803569408	[265,230]	[59,102]	-8	hSpCas9	negative selection	4507646
224300636	224300658	1	-	27760321	OCIAML2	viability	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	-0.09901390466749915	[155,149]	[88,150]	-1	hSpCas9	negative selection	4507647
224303818	224303840	1	-	27760321	OCIAML2	viability	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.8788018664188966	[1108,917]	[167,292]	-9	hSpCas9	negative selection	4507648
224304801	224304823	1	-	27760321	OCIAML2	viability	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-0.059601480816447006	[257,256]	[168,241]	-1	hSpCas9	negative selection	4507649
224294320	224294342	1	+	27760321	MV411	viability	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-0.9127073332327075	[550,449]	[130,239]	-6	hSpCas9	negative selection	4591108
224296491	224296513	1	+	27760321	MV411	viability	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-4.818754368322898	[265,230]	[0,12]	-9	hSpCas9	negative selection	4591109
224300636	224300658	1	-	27760321	MV411	viability	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	1.5043503729239145	[155,149]	[423,80]	9	hSpCas9	negative selection	4591110
224303818	224303840	1	-	27760321	MV411	viability	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-0.3510735724101942	[1108,917]	[537,497]	-2	hSpCas9	negative selection	4591111
224304801	224304823	1	-	27760321	MV411	viability	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-1.2117730831843367	[257,256]	[63,87]	-7	hSpCas9	negative selection	4591112
224294320	224294342	1	+	27760321	HL60	viability	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-0.25709416921387057	[550,449]	[303,378]	-3	hSpCas9	negative selection	4674571
224296491	224296513	1	+	27760321	HL60	viability	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-1.8407070490017126	[265,230]	[40,72]	-9	hSpCas9	negative selection	4674572
224300636	224300658	1	-	27760321	HL60	viability	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	0.17177223176550993	[155,149]	[91,192]	2	hSpCas9	negative selection	4674573
224303818	224303840	1	-	27760321	HL60	viability	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.1286898642556709	[1108,917]	[374,378]	-8	hSpCas9	negative selection	4674574
224304801	224304823	1	-	27760321	HL60	viability	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-2.5446714253034632	[257,256]	[24,47]	-9	hSpCas9	negative selection	4674575
224294320	224294342	1	+	27760321	HT1080	viability	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-7.3177883281333544	[449,350]	[0,0]	-9	hSpCas9	negative selection	4758034
224296491	224296513	1	+	27760321	HT1080	viability	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-6.355035234097407	[230,179]	[0,0]	-9	hSpCas9	negative selection	4758035
224300636	224300658	1	-	27760321	HT1080	viability	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	-4.7328258274121975	[149,116]	[1,1]	-8	hSpCas9	negative selection	4758036
224303818	224303840	1	-	27760321	HT1080	viability	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-3.6532790721299335	[917,716]	[33,16]	-8	hSpCas9	negative selection	4758037
224304801	224304823	1	-	27760321	HT1080	viability	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-6.511573917230434	[256,200]	[0,0]	-9	hSpCas9	negative selection	4758038
224294320	224294342	1	+	27760321	HT29	viability after 7 days	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-0.1843432446523805	[449,350]	[316,493,525]	-3	hSpCas9	negative selection	4841497
224296491	224296513	1	+	27760321	HT29	viability after 7 days	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-1.0944719148856772	[230,179]	[129,121,119]	-8	hSpCas9	negative selection	4841498
224300636	224300658	1	-	27760321	HT29	viability after 7 days	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	-0.09451712048863192	[149,116]	[174,82,223]	-1	hSpCas9	negative selection	4841499
224303818	224303840	1	-	27760321	HT29	viability after 7 days	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-0.8354248198978869	[917,716]	[753,641,399]	-8	hSpCas9	negative selection	4841500
224304801	224304823	1	-	27760321	HT29	viability after 7 days	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-1.1146960821296459	[256,200]	[187,85,140]	-8	hSpCas9	negative selection	4841501
224294320	224294342	1	+	27760321	HT29	viability after 25 days	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-5.0819852103899565	[449,350]	[4,22,12]	-9	hSpCas9	negative selection	4924960
224296491	224296513	1	+	27760321	HT29	viability after 25 days	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-6.729861938614908	[230,179]	[0,0,4]	-9	hSpCas9	negative selection	4924961
224300636	224300658	1	-	27760321	HT29	viability after 25 days	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	0.5909731808175692	[149,116]	[248,198,240]	6	hSpCas9	negative selection	4924962
224303818	224303840	1	-	27760321	HT29	viability after 25 days	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-4.347230066376717	[917,716]	[89,14,27]	-9	hSpCas9	negative selection	4924963
224304801	224304823	1	-	27760321	HT29	viability after 25 days	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-2.3251558947776005	[256,200]	[54,52,47]	-8	hSpCas9	negative selection	4924964
224294320	224294342	1	+	27760321	HT29	viability after 22 days	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-4.576726193308442	[449,350]	[0,6,50]	-9	hSpCas9	negative selection	5008423
224296491	224296513	1	+	27760321	HT29	viability after 22 days	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-5.217319106932457	[230,179]	[11,0,5]	-9	hSpCas9	negative selection	5008424
224300636	224300658	1	-	27760321	HT29	viability after 22 days	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	0.01501166130930387	[149,116]	[188,113,163]	0	hSpCas9	negative selection	5008425
224303818	224303840	1	-	27760321	HT29	viability after 22 days	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-4.072562414445607	[917,716]	[95,60,9]	-9	hSpCas9	negative selection	5008426
224304801	224304823	1	-	27760321	HT29	viability after 22 days	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-1.7331412869257976	[256,200]	[122,8,105]	-8	hSpCas9	negative selection	5008427
224294320	224294342	1	+	27760321	HT29	viability after 19 days	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-3.3661874403386007	[449,350]	[16,112,1]	-9	hSpCas9	negative selection	5091886
224296491	224296513	1	+	27760321	HT29	viability after 19 days	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-6.374948186874789	[230,179]	[6,0,0]	-9	hSpCas9	negative selection	5091887
224300636	224300658	1	-	27760321	HT29	viability after 19 days	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	0.7877394737048855	[149,116]	[298,492,11]	7	hSpCas9	negative selection	5091888
224303818	224303840	1	-	27760321	HT29	viability after 19 days	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-5.129523052127553	[917,716]	[82,2,0]	-9	hSpCas9	negative selection	5091889
224304801	224304823	1	-	27760321	HT29	viability after 19 days	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-2.4887696828587935	[256,200]	[51,0,85]	-8	hSpCas9	negative selection	5091890
224294320	224294342	1	+	27760321	HT29	viability after 16 days	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-4.039552228683181	[449,350]	[24,8,47]	-9	hSpCas9	negative selection	5175349
224296491	224296513	1	+	27760321	HT29	viability after 16 days	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-3.1915190557409088	[230,179]	[15,48,8]	-9	hSpCas9	negative selection	5175350
224300636	224300658	1	-	27760321	HT29	viability after 16 days	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	0.7296284509265247	[149,116]	[294,301,148]	8	hSpCas9	negative selection	5175351
224303818	224303840	1	-	27760321	HT29	viability after 16 days	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-4.122967611141255	[917,716]	[15,91,44]	-9	hSpCas9	negative selection	5175352
224304801	224304823	1	-	27760321	HT29	viability after 16 days	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-1.7541097093838252	[256,200]	[11,107,100]	-8	hSpCas9	negative selection	5175353
224294320	224294342	1	+	27760321	HT29	viability after 13 days	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-3.0663400528122464	[449,350]	[19,82,62]	-9	hSpCas9	negative selection	5258812
224296491	224296513	1	+	27760321	HT29	viability after 13 days	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-3.9005534311763177	[230,179]	[17,15,13]	-9	hSpCas9	negative selection	5258813
224300636	224300658	1	-	27760321	HT29	viability after 13 days	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	-0.1419554088306687	[149,116]	[167,95,155]	-2	hSpCas9	negative selection	5258814
224303818	224303840	1	-	27760321	HT29	viability after 13 days	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-2.7625384668858555	[917,716]	[218,92,108]	-9	hSpCas9	negative selection	5258815
224304801	224304823	1	-	27760321	HT29	viability after 13 days	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-2.1353804109577617	[256,200]	[39,21,115]	-8	hSpCas9	negative selection	5258816
224294320	224294342	1	+	27760321	HT29	viability after 10 days	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-1.5568984787101434	[449,350]	[112,198,197]	-8	hSpCas9	negative selection	5342275
224296491	224296513	1	+	27760321	HT29	viability after 10 days	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-0.6554791956557839	[230,179]	[191,237,62]	-6	hSpCas9	negative selection	5342276
224300636	224300658	1	-	27760321	HT29	viability after 10 days	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	0.8494499164618633	[149,116]	[286,247,362]	9	hSpCas9	negative selection	5342277
224303818	224303840	1	-	27760321	HT29	viability after 10 days	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.806002877869152	[917,716]	[452,225,196]	-9	hSpCas9	negative selection	5342278
224304801	224304823	1	-	27760321	HT29	viability after 10 days	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-1.9820800939818675	[256,200]	[75,47,91]	-9	hSpCas9	negative selection	5342279
224294320	224294342	1	+	27760321	MOLM13	viability	TCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-1.7326965659960658	[550,449]	[83,84]	-7	hSpCas9	negative selection	5425738
224296491	224296513	1	+	27760321	MOLM13	viability	TTAAACTAACCATCCATGCAGG	NVL	ENSG00000143748	-7.127760103858017	[265,230]	[0,0]	-9	hSpCas9	negative selection	5425739
224300636	224300658	1	-	27760321	MOLM13	viability	GACCTGCCAATTTTGAAAGTGG	NVL	ENSG00000143748	0.7406790504066716	[155,149]	[137,149]	5	hSpCas9	negative selection	5425740
224303818	224303840	1	-	27760321	MOLM13	viability	ATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.1664890870128726	[1108,917]	[83,397]	-6	hSpCas9	negative selection	5425741
224304801	224304823	1	-	27760321	MOLM13	viability	TGTTTACCAGCTAAAGCCAGGG	NVL	ENSG00000143748	-0.7879955355164577	[257,256]	[78,88]	-5	hSpCas9	negative selection	5425742
224329907	224329930	1	+	27661255	K562	viability	GGCCCCGGCAGCACCAACTAAGG	NVL	ENSG00000143748	-0.9655025529658234	[1149,1352]	[544,480]	-8	dCas9-KRAB	negative selection	5498001
224329940	224329963	1	+	27661255	K562	viability	GCACGCCCAGACCCAGACTGGGG	NVL	ENSG00000143748	-1.1858275543639318	[269,260]	[102,84]	-8	dCas9-KRAB	negative selection	5498002
224330145	224330168	1	-	27661255	K562	viability	GGAGCTGGCGGTCCGAGCTGTGG	NVL	ENSG00000143748	-5.301076506500207	[784,886]	[24,9]	-9	dCas9-KRAB	negative selection	5498003
224330160	224330183	1	-	27661255	K562	viability	GCCCCCGGTTGACTAGGAGCTGG	NVL	ENSG00000143748	-3.0347578024090476	[530,840]	[88,46]	-9	dCas9-KRAB	negative selection	5498004
224303821	224303844	1	-	27260156	BXPC3	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.5515418519923472	[867]	[479,639,772,592]	-8	hSpCas9	negative selection	5559234
224303784	224303807	1	-	27260156	BXPC3	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.5096136220671816	[788]	[1114,1019,1228,1365]	9	hSpCas9	negative selection	5559235
224300605	224300628	1	-	27260156	BXPC3	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.9977351656037211	[1086]	[465,628,568,622]	-9	hSpCas9	negative selection	5559236
224305120	224305143	1	-	27260156	BXPC3	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.8815143340863725	[285]	[166,116,163,207]	-9	hSpCas9	negative selection	5623492
224305033	224305056	1	-	27260156	BXPC3	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.8210910072850672	[172]	[98,70,103,141]	-9	hSpCas9	negative selection	5623493
224300561	224300584	1	-	27260156	BXPC3	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.8813783382116642	[282]	[90,49,72,110]	-9	hSpCas9	negative selection	5623494
224303821	224303844	1	-	27260156	A673	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.43142032277546855	[867]	[724,648,939,771]	-8	hSpCas9	negative selection	5680485
224303784	224303807	1	-	27260156	A673	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.4164153310911898	[788]	[1552,1182,1134,1217]	8	hSpCas9	negative selection	5680486
224300605	224300628	1	-	27260156	A673	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.6111808965392868	[1086]	[1029,847,776,777]	-9	hSpCas9	negative selection	5680487
224305120	224305143	1	-	27260156	A673	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.6455969678778837	[285]	[196,189,200,291]	-9	hSpCas9	negative selection	5744743
224305033	224305056	1	-	27260156	A673	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.7234101865012561	[172]	[131,138,99,132]	-9	hSpCas9	negative selection	5744744
224300561	224300584	1	-	27260156	A673	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.8947863616797423	[282]	[188,197,163,179]	-9	hSpCas9	negative selection	5744745
224303821	224303844	1	-	27260156	A375	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.7856028686171784	[867]	[548,513,608,658]	-7	hSpCas9	negative selection	5801736
224303784	224303807	1	-	27260156	A375	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.729963360606698	[788]	[1550,1823,1465,1331]	9	hSpCas9	negative selection	5801737
224300605	224300628	1	-	27260156	A375	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-2.218290184347822	[1086]	[248,149,437,239]	-9	hSpCas9	negative selection	5801738
224305120	224305143	1	-	27260156	A375	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.60955258299442	[285]	[256,264,116,239]	-7	hSpCas9	negative selection	5865994
224305033	224305056	1	-	27260156	A375	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.8549225492416954	[172]	[155,97,61,126]	-8	hSpCas9	negative selection	5865995
224300561	224300584	1	-	27260156	A375	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-2.784786384416575	[282]	[14,76,4,92]	-9	hSpCas9	negative selection	5865996
224303821	224303844	1	-	27260156	COLO741	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.236342099264918	[867]	[912,854,1043]	-5	hSpCas9	negative selection	5922987
224303784	224303807	1	-	27260156	COLO741	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.2913158904119253	[788]	[1613,1066,1061]	6	hSpCas9	negative selection	5922988
224300605	224300628	1	-	27260156	COLO741	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.9242457678498679	[1086]	[787,711,700]	-9	hSpCas9	negative selection	5922989
224305120	224305143	1	-	27260156	COLO741	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-1.0552987587373333	[285]	[217,169,144]	-9	hSpCas9	negative selection	5987245
224305033	224305056	1	-	27260156	COLO741	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.5443870118741134	[172]	[116,175,157]	-8	hSpCas9	negative selection	5987246
224300561	224300584	1	-	27260156	COLO741	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.9225047705946773	[282]	[285,161,135]	-9	hSpCas9	negative selection	5987247
224303821	224303844	1	-	27260156	CAL120	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.8486447387293896	[867]	[744,531,544]	-8	hSpCas9	negative selection	6044238
224303784	224303807	1	-	27260156	CAL120	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.44364018952092277	[788]	[1678,1205,1174]	6	hSpCas9	negative selection	6044239
224300605	224300628	1	-	27260156	CAL120	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-1.8403118388605257	[1086]	[461,375,308]	-9	hSpCas9	negative selection	6044240
224305120	224305143	1	-	27260156	CAL120	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-1.544369239712394	[285]	[118,93,151]	-9	hSpCas9	negative selection	6108496
224305033	224305056	1	-	27260156	CAL120	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-2.737247193907544	[172]	[59,7,32]	-9	hSpCas9	negative selection	6108497
224300561	224300584	1	-	27260156	CAL120	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-2.7372785902555257	[282]	[120,12,34]	-9	hSpCas9	negative selection	6108498
224303821	224303844	1	-	27260156	CADOES1	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.6552636440264025	[867]	[350,606,426,671]	-8	hSpCas9	negative selection	6165489
224303784	224303807	1	-	27260156	CADOES1	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.5838398626157304	[788]	[1219,973,1127,1075]	8	hSpCas9	negative selection	6165490
224300605	224300628	1	-	27260156	CADOES1	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.2275062724137603	[1086]	[855,646,970,983]	-4	hSpCas9	negative selection	6165491
224305120	224305143	1	-	27260156	CADOES1	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.5020333358517057	[285]	[181,165,170,233]	-7	hSpCas9	negative selection	6229747
224305033	224305056	1	-	27260156	CADOES1	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.7538879660556854	[172]	[58,91,153,75]	-8	hSpCas9	negative selection	6229748
224300561	224300584	1	-	27260156	CADOES1	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.2780865980627936	[282]	[139,119,92,79]	-9	hSpCas9	negative selection	6229749
224303821	224303844	1	-	27260156	EWS502	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.8088576268230983	[867]	[316,631,560,614]	-8	hSpCas9	negative selection	6286740
224303784	224303807	1	-	27260156	EWS502	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.41324846448564756	[788]	[959,1222,988,1300]	7	hSpCas9	negative selection	6286741
224300605	224300628	1	-	27260156	EWS502	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.130742146268104	[1086]	[885,1135,1213,979]	-2	hSpCas9	negative selection	6286742
224305120	224305143	1	-	27260156	EWS502	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.8889210450038312	[285]	[157,149,170,176]	-8	hSpCas9	negative selection	6350998
224305033	224305056	1	-	27260156	EWS502	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.1926944175898138	[172]	[67,145,45,56]	-9	hSpCas9	negative selection	6350999
224300561	224300584	1	-	27260156	EWS502	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-2.330800518484848	[282]	[36,54,96,51]	-9	hSpCas9	negative selection	6351000
224303821	224303844	1	-	27260156	EW8	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.3571904804376024	[867]	[640,555,407,623]	-6	hSpCas9	negative selection	6407991
224303784	224303807	1	-	27260156	EW8	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.6101746649835573	[788]	[926,1179,917,881]	9	hSpCas9	negative selection	6407992
224300605	224300628	1	-	27260156	EW8	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.4897784383986534	[1086]	[748,545,594,635]	-7	hSpCas9	negative selection	6407993
224305120	224305143	1	-	27260156	EW8	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.8504143680720833	[285]	[109,172,98,134]	-9	hSpCas9	negative selection	6472249
224305033	224305056	1	-	27260156	EW8	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.6051653762032876	[172]	[55,154,78,76]	-8	hSpCas9	negative selection	6472250
224300561	224300584	1	-	27260156	EW8	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.352092858964069	[282]	[50,86,135,72]	-9	hSpCas9	negative selection	6472251
224303821	224303844	1	-	27260156	CORL105	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.6741372621824604	[867]	[668,488,832,590]	-8	hSpCas9	negative selection	6529242
224303784	224303807	1	-	27260156	CORL105	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.6264095204447051	[788]	[1517,1116,2054,1121]	9	hSpCas9	negative selection	6529243
224300605	224300628	1	-	27260156	CORL105	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-1.289204583548051	[1086]	[477,446,613,557]	-9	hSpCas9	negative selection	6529244
224305120	224305143	1	-	27260156	CORL105	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.5111898032776381	[285]	[314,276,190,151]	-7	hSpCas9	negative selection	6593500
224305033	224305056	1	-	27260156	CORL105	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.1079231356599806	[172]	[43,51,227,71]	-9	hSpCas9	negative selection	6593501
224300561	224300584	1	-	27260156	CORL105	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.8929934662150291	[282]	[54,117,304,251]	-9	hSpCas9	negative selection	6593502
224303821	224303844	1	-	27260156	HS294T	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.9874503698488298	[867]	[131,128,198,231]	-8	hSpCas9	negative selection	6650493
224303784	224303807	1	-	27260156	HS294T	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.2634895607732788	[788]	[319,366,284,521]	3	hSpCas9	negative selection	6650494
224300605	224300628	1	-	27260156	HS294T	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-1.4307042232493774	[1086]	[72,127,195,250]	-9	hSpCas9	negative selection	6650495
224305120	224305143	1	-	27260156	HS294T	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.40643059711064145	[285]	[49,43,60,202]	-5	hSpCas9	negative selection	6714751
224305033	224305056	1	-	27260156	HS294T	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.750760210982473	[172]	[21,2,38,14]	-9	hSpCas9	negative selection	6714752
224300561	224300584	1	-	27260156	HS294T	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.9847124669891287	[282]	[18,14,33,46]	-9	hSpCas9	negative selection	6714753
224303821	224303844	1	-	27260156	HCC44	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.7644590914127958	[867]	[595,554,589,572]	-8	hSpCas9	negative selection	6771744
224303784	224303807	1	-	27260156	HCC44	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.42869298564627134	[788]	[1136,1324,1180,1126]	7	hSpCas9	negative selection	6771745
224300605	224300628	1	-	27260156	HCC44	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-2.4901619640303387	[1086]	[257,123,377,159]	-9	hSpCas9	negative selection	6771746
224305120	224305143	1	-	27260156	HCC44	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-1.0187720932287974	[285]	[128,127,159,219]	-8	hSpCas9	negative selection	6836002
224305033	224305056	1	-	27260156	HCC44	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.8697624847160101	[172]	[20,36,95,65]	-9	hSpCas9	negative selection	6836003
224300561	224300584	1	-	27260156	HCC44	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-3.488555153012562	[282]	[57,38,6,7]	-9	hSpCas9	negative selection	6836004
224303821	224303844	1	-	27260156	G402	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.6316296299870526	[867]	[1007,704,427,640]	-7	hSpCas9	negative selection	6892995
224303784	224303807	1	-	27260156	G402	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.7711985364574994	[788]	[1483,1989,1505,1585]	8	hSpCas9	negative selection	6892996
224300605	224300628	1	-	27260156	G402	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.3290717077082431	[1086]	[1489,1026,1124,657]	-4	hSpCas9	negative selection	6892997
224305120	224305143	1	-	27260156	G402	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-1.4203937919641518	[285]	[215,40,157,113]	-9	hSpCas9	negative selection	6957253
224305033	224305056	1	-	27260156	G402	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.9228852529438183	[172]	[64,30,104,22]	-9	hSpCas9	negative selection	6957254
224300561	224300584	1	-	27260156	G402	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-3.2853015726683252	[282]	[43,37,26,33]	-9	hSpCas9	negative selection	6957255
224303821	224303844	1	-	27260156	L33	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.4274259342548941	[867]	[563,285,448,607]	-7	hSpCas9	negative selection	7014246
224303784	224303807	1	-	27260156	L33	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	-0.021854001217170516	[788]	[730,311,489,836]	0	hSpCas9	negative selection	7014247
224300605	224300628	1	-	27260156	L33	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.33736461885325897	[1086]	[679,357,499,1093]	-7	hSpCas9	negative selection	7014248
224305120	224305143	1	-	27260156	L33	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.6123200551983103	[285]	[212,94,99,143]	-8	hSpCas9	negative selection	7078504
224305033	224305056	1	-	27260156	L33	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.3887904177515178	[172]	[187,42,88,92]	-7	hSpCas9	negative selection	7078505
224300561	224300584	1	-	27260156	L33	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.392790709058462	[282]	[127,38,64,103]	-9	hSpCas9	negative selection	7078506
224303821	224303844	1	-	27260156	K562	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-1.0793465804163251	[867]	[497,279,385,305]	-8	hSpCas9	negative selection	7135497
224303784	224303807	1	-	27260156	K562	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.7252692239490679	[788]	[1293,1343,1112,922]	8	hSpCas9	negative selection	7135498
224300605	224300628	1	-	27260156	K562	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	0.0853890484973221	[1086]	[1309,984,1170,684]	1	hSpCas9	negative selection	7135499
224305120	224305143	1	-	27260156	K562	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	0.19810361469400262	[285]	[392,184,153,418]	2	hSpCas9	negative selection	7199755
224305033	224305056	1	-	27260156	K562	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.5304611439498577	[172]	[127,23,49,18]	-9	hSpCas9	negative selection	7199756
224300561	224300584	1	-	27260156	K562	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-2.762144117640394	[282]	[28,71,28,20]	-9	hSpCas9	negative selection	7199757
224303821	224303844	1	-	27260156	HT29	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.9419592122652964	[867]	[662,411,476,627]	-8	hSpCas9	negative selection	7256748
224303784	224303807	1	-	27260156	HT29	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.3379809459040717	[788]	[1115,1550,1098,1108]	6	hSpCas9	negative selection	7256749
224300605	224300628	1	-	27260156	HT29	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.9906940018119873	[1086]	[712,746,650,566]	-8	hSpCas9	negative selection	7256750
224305120	224305143	1	-	27260156	HT29	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-1.1323746533957348	[285]	[156,314,127,58]	-9	hSpCas9	negative selection	7321006
224305033	224305056	1	-	27260156	HT29	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.4378968999559314	[172]	[110,105,20,76]	-9	hSpCas9	negative selection	7321007
224300561	224300584	1	-	27260156	HT29	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.6133798020400087	[282]	[94,159,158,45]	-9	hSpCas9	negative selection	7321008
224303821	224303844	1	-	27260156	MHHES1	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.4387548441520642	[867]	[928,723,673,595]	-7	hSpCas9	negative selection	7377999
224303784	224303807	1	-	27260156	MHHES1	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.4010235660664647	[788]	[1244,1386,1265,870]	7	hSpCas9	negative selection	7378000
224300605	224300628	1	-	27260156	MHHES1	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.7732444532144718	[1086]	[1090,1047,390,456]	-8	hSpCas9	negative selection	7378001
224305120	224305143	1	-	27260156	MHHES1	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.7278178341064001	[285]	[273,215,177,131]	-8	hSpCas9	negative selection	7442257
224305033	224305056	1	-	27260156	MHHES1	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.11561708010478822	[172]	[298,141,163,131]	-2	hSpCas9	negative selection	7442258
224300561	224300584	1	-	27260156	MHHES1	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.549451948047618	[282]	[82,97,123,120]	-9	hSpCas9	negative selection	7442259
224303821	224303844	1	-	27260156	MEWO	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.3926268578599949	[867]	[808,517,565]	-7	hSpCas9	negative selection	7499250
224303784	224303807	1	-	27260156	MEWO	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.25348062124679793	[788]	[1042,720,907]	5	hSpCas9	negative selection	7499251
224300605	224300628	1	-	27260156	MEWO	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.4625845111674647	[1086]	[946,798,507]	-7	hSpCas9	negative selection	7499252
224305120	224305143	1	-	27260156	MEWO	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.6455107264062903	[285]	[108,188,202]	-8	hSpCas9	negative selection	7563508
224305033	224305056	1	-	27260156	MEWO	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.706284004302701	[172]	[112,149,36]	-8	hSpCas9	negative selection	7563509
224300561	224300584	1	-	27260156	MEWO	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.5030938987897007	[282]	[112,92,77]	-9	hSpCas9	negative selection	7563510
224303821	224303844	1	-	27260156	LNCAPCLONEFGC	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.4329714114707967	[867]	[735,498,596,501]	-6	hSpCas9	negative selection	7620501
224303784	224303807	1	-	27260156	LNCAPCLONEFGC	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.5795394558999838	[788]	[962,958,1190,1185]	8	hSpCas9	negative selection	7620502
224300605	224300628	1	-	27260156	LNCAPCLONEFGC	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.9140006599978283	[1086]	[574,490,562,467]	-8	hSpCas9	negative selection	7620503
224305120	224305143	1	-	27260156	LNCAPCLONEFGC	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-1.7021257972977475	[285]	[57,88,104,69]	-9	hSpCas9	negative selection	7684759
224305033	224305056	1	-	27260156	LNCAPCLONEFGC	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.7698244555366331	[172]	[30,53,48,49]	-9	hSpCas9	negative selection	7684760
224300561	224300584	1	-	27260156	LNCAPCLONEFGC	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.9519366594288075	[282]	[44,78,21,111]	-9	hSpCas9	negative selection	7684761
224303821	224303844	1	-	27260156	PANC0327	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-1.0558766486463234	[867]	[619,399,265,213]	-8	hSpCas9	negative selection	7741752
224303784	224303807	1	-	27260156	PANC0327	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.6127769251824644	[788]	[1178,847,1339,957]	8	hSpCas9	negative selection	7741753
224300605	224300628	1	-	27260156	PANC0327	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-1.6932151057514755	[1086]	[318,265,228,385]	-9	hSpCas9	negative selection	7741754
224305120	224305143	1	-	27260156	PANC0327	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.30313039446720125	[285]	[183,152,391,99]	-4	hSpCas9	negative selection	7806010
224305033	224305056	1	-	27260156	PANC0327	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.8960837722810155	[172]	[26,17,61,59]	-9	hSpCas9	negative selection	7806011
224300561	224300584	1	-	27260156	PANC0327	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.8193545941703096	[282]	[155,188,162,56]	-8	hSpCas9	negative selection	7806012
224303821	224303844	1	-	27260156	NCIH2009	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-1.0399920358274166	[867]	[745,602,449]	-8	hSpCas9	negative selection	7863003
224303784	224303807	1	-	27260156	NCIH2009	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.2781932635943778	[788]	[1184,1453,1336]	4	hSpCas9	negative selection	7863004
224300605	224300628	1	-	27260156	NCIH2009	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-2.480042091588431	[1086]	[338,347,140]	-9	hSpCas9	negative selection	7863005
224305120	224305143	1	-	27260156	NCIH2009	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-1.600148363609756	[285]	[269,103,48]	-9	hSpCas9	negative selection	7927261
224305033	224305056	1	-	27260156	NCIH2009	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-2.0483593044041717	[172]	[96,48,36]	-9	hSpCas9	negative selection	7927262
224300561	224300584	1	-	27260156	NCIH2009	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-3.184687123634252	[282]	[75,32,27]	-9	hSpCas9	negative selection	7927263
224303821	224303844	1	-	27260156	NCIH1373	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-1.2066595674811118	[867]	[545,469,346,86]	-8	hSpCas9	negative selection	7984254
224303784	224303807	1	-	27260156	NCIH1373	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.534365719682379	[788]	[1759,931,1118,375]	5	hSpCas9	negative selection	7984255
224300605	224300628	1	-	27260156	NCIH1373	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-2.0456675669165256	[1086]	[428,154,168,124]	-9	hSpCas9	negative selection	7984256
224305120	224305143	1	-	27260156	NCIH1373	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.8996671667979312	[285]	[162,189,284,8]	-7	hSpCas9	negative selection	8048512
224305033	224305056	1	-	27260156	NCIH1373	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.0683607958347632	[172]	[103,120,41,26]	-8	hSpCas9	negative selection	8048513
224300561	224300584	1	-	27260156	NCIH1373	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-3.134228035008742	[282]	[14,38,9,20]	-9	hSpCas9	negative selection	8048514
224303821	224303844	1	-	27260156	PATU8902	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.7500036226286264	[867]	[920,656,665,624]	-6	hSpCas9	negative selection	8105505
224303784	224303807	1	-	27260156	PATU8902	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	1.1830661474273276	[788]	[2415,2492,2641,2354]	9	hSpCas9	negative selection	8105506
224300605	224300628	1	-	27260156	PATU8902	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-2.809711918123076	[1086]	[143,233,199,298]	-9	hSpCas9	negative selection	8105507
224305120	224305143	1	-	27260156	PATU8902	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-1.136165058362497	[285]	[314,351,49,19]	-7	hSpCas9	negative selection	8169763
224305033	224305056	1	-	27260156	PATU8902	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.0050141680164488	[172]	[9,196,220,13]	-7	hSpCas9	negative selection	8169764
224300561	224300584	1	-	27260156	PATU8902	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-2.112686850604275	[282]	[282,7,6,83]	-9	hSpCas9	negative selection	8169765
224303821	224303844	1	-	27260156	PANC1	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-1.2045134691738941	[867]	[306,397,421,198]	-9	hSpCas9	negative selection	8226756
224303784	224303807	1	-	27260156	PANC1	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.7285781078648734	[788]	[965,1550,1315,788]	9	hSpCas9	negative selection	8226757
224300605	224300628	1	-	27260156	PANC1	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-1.0769595850937477	[1086]	[317,620,492,380]	-8	hSpCas9	negative selection	8226758
224305120	224305143	1	-	27260156	PANC1	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.882625007868393	[285]	[123,243,117,76]	-8	hSpCas9	negative selection	8291014
224305033	224305056	1	-	27260156	PANC1	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-2.05857782918242	[172]	[45,33,55,9]	-9	hSpCas9	negative selection	8291015
224300561	224300584	1	-	27260156	PANC1	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-2.538593271627342	[282]	[85,40,21,19]	-9	hSpCas9	negative selection	8291016
224303821	224303844	1	-	27260156	PANC0813	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.7658831244121032	[867]	[716,598,512,579]	-8	hSpCas9	negative selection	8348007
224303784	224303807	1	-	27260156	PANC0813	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.27282564792338126	[788]	[1373,1112,1090,932]	4	hSpCas9	negative selection	8348008
224300605	224300628	1	-	27260156	PANC0813	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-1.7422864345690767	[1086]	[519,351,382,288]	-9	hSpCas9	negative selection	8348009
224305120	224305143	1	-	27260156	PANC0813	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-1.0319968393825034	[285]	[177,219,184,79]	-8	hSpCas9	negative selection	8412265
224305033	224305056	1	-	27260156	PANC0813	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.828842802921748	[172]	[55,53,84,34]	-9	hSpCas9	negative selection	8412266
224300561	224300584	1	-	27260156	PANC0813	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.9232786916088722	[282]	[114,39,142,56]	-9	hSpCas9	negative selection	8412267
224303821	224303844	1	-	27260156	RDES	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.5208510170013056	[867]	[497,777,824,701]	-7	hSpCas9	negative selection	8469258
224303784	224303807	1	-	27260156	RDES	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.7397286233004106	[788]	[1151,1368,1628,2044]	9	hSpCas9	negative selection	8469259
224300605	224300628	1	-	27260156	RDES	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.2425244826509142	[1086]	[841,1068,986,1389]	-4	hSpCas9	negative selection	8469260
224305120	224305143	1	-	27260156	RDES	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.9165027333266675	[285]	[124,165,196,223]	-9	hSpCas9	negative selection	8533516
224305033	224305056	1	-	27260156	RDES	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.7939092997036674	[172]	[57,83,208,125]	-8	hSpCas9	negative selection	8533517
224300561	224300584	1	-	27260156	RDES	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.5574851895612403	[282]	[78,88,116,172]	-9	hSpCas9	negative selection	8533518
224303821	224303844	1	-	27260156	PC3	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.09258067405045356	[867]	[516,808,1426,779]	-2	hSpCas9	negative selection	8590509
224303784	224303807	1	-	27260156	PC3	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.16010863697438005	[788]	[631,818,1589,760]	3	hSpCas9	negative selection	8590510
224300605	224300628	1	-	27260156	PC3	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.532523492354577	[1086]	[411,740,1331,824]	-8	hSpCas9	negative selection	8590511
224305120	224305143	1	-	27260156	PC3	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.8677274522381038	[285]	[87,61,432,172]	-9	hSpCas9	negative selection	8654767
224305033	224305056	1	-	27260156	PC3	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.5671020557333972	[172]	[47,25,107,69]	-9	hSpCas9	negative selection	8654768
224300561	224300584	1	-	27260156	PC3	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.0891355245246133	[282]	[89,102,188,178]	-9	hSpCas9	negative selection	8654769
224303821	224303844	1	-	27260156	PATU8988T	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.50641461639339	[867]	[437,618,652,658]	-7	hSpCas9	negative selection	8711760
224303784	224303807	1	-	27260156	PATU8988T	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.5988374595795547	[788]	[802,1467,1248,1123]	8	hSpCas9	negative selection	8711761
224300605	224300628	1	-	27260156	PATU8988T	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-1.9097058168463876	[1086]	[282,179,175,487]	-9	hSpCas9	negative selection	8711762
224305120	224305143	1	-	27260156	PATU8988T	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-1.0458772306304291	[285]	[156,164,141,68]	-9	hSpCas9	negative selection	8776018
224305033	224305056	1	-	27260156	PATU8988T	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.8042965868552598	[172]	[172,62,33,111]	-8	hSpCas9	negative selection	8776019
224300561	224300584	1	-	27260156	PATU8988T	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.3129261079285648	[282]	[97,48,250,27]	-9	hSpCas9	negative selection	8776020
224303821	224303844	1	-	27260156	T47D	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.6137679277590157	[867]	[642,614,663,726]	-8	hSpCas9	negative selection	8833011
224303784	224303807	1	-	27260156	T47D	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.3449579734823387	[788]	[1204,1001,1221,1256]	7	hSpCas9	negative selection	8833012
224300605	224300628	1	-	27260156	T47D	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.42196789055531714	[1086]	[973,949,986,865]	-7	hSpCas9	negative selection	8833013
224305120	224305143	1	-	27260156	T47D	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.6450061372638543	[285]	[271,137,207,241]	-8	hSpCas9	negative selection	8897269
224305033	224305056	1	-	27260156	T47D	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.5816387383647226	[172]	[90,18,58,105]	-9	hSpCas9	negative selection	8897270
224300561	224300584	1	-	27260156	T47D	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.579538398123161	[282]	[102,74,145,119]	-9	hSpCas9	negative selection	8897271
224303821	224303844	1	-	27260156	SU8686	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-1.2980576259102787	[867]	[311,290,305,527]	-9	hSpCas9	negative selection	8954262
224303784	224303807	1	-	27260156	SU8686	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.2829742829164925	[788]	[821,843,970,1238]	5	hSpCas9	negative selection	8954263
224300605	224300628	1	-	27260156	SU8686	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-2.293852491777181	[1086]	[166,260,201,252]	-9	hSpCas9	negative selection	8954264
224305120	224305143	1	-	27260156	SU8686	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-1.1346770882553001	[285]	[175,86,101,153]	-8	hSpCas9	negative selection	9018520
224305033	224305056	1	-	27260156	SU8686	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.4880020063733297	[172]	[33,44,83,91]	-9	hSpCas9	negative selection	9018521
224300561	224300584	1	-	27260156	SU8686	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-2.770989261300525	[282]	[32,20,76,36]	-9	hSpCas9	negative selection	9018522
224303821	224303844	1	-	27260156	SKES1	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.2654218861671298	[867]	[708,949,663,592]	-5	hSpCas9	negative selection	9075513
224303784	224303807	1	-	27260156	SKES1	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.41673684004356826	[788]	[1211,1143,1007,881]	8	hSpCas9	negative selection	9075514
224300605	224300628	1	-	27260156	SKES1	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.03371455176314231	[1086]	[1151,1040,1042,1006]	0	hSpCas9	negative selection	9075515
224305120	224305143	1	-	27260156	SKES1	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.1326268692371828	[285]	[357,324,227,160]	-3	hSpCas9	negative selection	9139771
224305033	224305056	1	-	27260156	SKES1	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.4277559726318374	[172]	[111,116,130,145]	-7	hSpCas9	negative selection	9139772
224300561	224300584	1	-	27260156	SKES1	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.2184166324272212	[282]	[167,181,120,36]	-9	hSpCas9	negative selection	9139773
224303821	224303844	1	-	27260156	TOV112D	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.23659894375040047	[867]	[768,637,774,745]	-4	hSpCas9	negative selection	9196764
224303784	224303807	1	-	27260156	TOV112D	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.6253373068412496	[788]	[1689,1643,749,941]	9	hSpCas9	negative selection	9196765
224300605	224300628	1	-	27260156	TOV112D	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.17963551012161738	[1086]	[929,1040,698,1183]	-4	hSpCas9	negative selection	9196766
224305120	224305143	1	-	27260156	TOV112D	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.6430038330624344	[285]	[215,216,184,127]	-8	hSpCas9	negative selection	9261022
224305033	224305056	1	-	27260156	TOV112D	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.8919681900796541	[172]	[89,61,71,139]	-9	hSpCas9	negative selection	9261023
224300561	224300584	1	-	27260156	TOV112D	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.6461352882971126	[282]	[186,115,237,167]	-8	hSpCas9	negative selection	9261024
224303821	224303844	1	-	27260156	TC71	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.3286156335917726	[867]	[762,714,733,751]	-7	hSpCas9	negative selection	9318015
224303784	224303807	1	-	27260156	TC71	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.2569014415862816	[788]	[1122,1082,836,1001]	6	hSpCas9	negative selection	9318016
224300605	224300628	1	-	27260156	TC71	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.043805967220132525	[1086]	[1194,1158,1076,1087]	-1	hSpCas9	negative selection	9318017
224305120	224305143	1	-	27260156	TC71	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.558057715962555	[285]	[129,244,222,237]	-9	hSpCas9	negative selection	9382273
224305033	224305056	1	-	27260156	TC71	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-1.1668740952830698	[172]	[69,113,76,68]	-9	hSpCas9	negative selection	9382274
224300561	224300584	1	-	27260156	TC71	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.5459043615614273	[282]	[241,248,131,209]	-9	hSpCas9	negative selection	9382275
224303821	224303844	1	-	27260156	TC32	viability	GCTCATACACATGCGTCACCCGG	NVL	ENSG00000143748	-0.45265929818376865	[867]	[594,451,826,566]	-7	hSpCas9	negative selection	9439266
224303784	224303807	1	-	27260156	TC32	viability	CTGGGCGTCGTGCCCCCTCGTGG	NVL	ENSG00000143748	0.48888860033145987	[788]	[991,573,1585,1241]	8	hSpCas9	negative selection	9439267
224300605	224300628	1	-	27260156	TC32	viability	GAGATTGTGTCTGGAGTATCCGG	NVL	ENSG00000143748	-0.5420990392120059	[1086]	[708,530,878,740]	-8	hSpCas9	negative selection	9439268
224305120	224305143	1	-	27260156	TC32	viability	GAGAGTGATATGAAACGGAAAGG	NVL	ENSG00000143748	-0.26423855130570195	[285]	[171,248,233,223]	-5	hSpCas9	negative selection	9503524
224305033	224305056	1	-	27260156	TC32	viability	GAAGCTGTCCTGCAAAAGAAAGG	NVL	ENSG00000143748	-0.8385683960138177	[172]	[87,59,131,97]	-9	hSpCas9	negative selection	9503525
224300561	224300584	1	-	27260156	TC32	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.7307354387195876	[282]	[118,120,92,315]	-9	hSpCas9	negative selection	9503526
224289483	224289506	1	-	27869803	HPAFII	viability after 27 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-2.468978686487364	[448]	[58,28,NaN]	-8	hSpCas9	negative selection	9532310
224294319	224294342	1	+	27869803	HPAFII	viability after 27 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-7.2688167584278	[559]	[2,0,NaN]	-9	hSpCas9	negative selection	9532313
224303803	224303826	1	-	27869803	HPAFII	viability after 27 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-0.42900275666984355	[202]	[21,126,NaN]	-3	hSpCas9	negative selection	9532314
224304800	224304823	1	-	27869803	HPAFII	viability after 27 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-6.490272060510194	[170]	[0,0,NaN]	-9	hSpCas9	negative selection	9532315
224308091	224308114	1	-	27869803	HPAFII	viability after 27 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-2.746098496689201	[470]	[25,45,NaN]	-9	hSpCas9	negative selection	9532316
224330052	224330075	1	+	27869803	HPAFII	viability after 27 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-0.23894725109439804	[240]	[114,100,NaN]	-2	hSpCas9	negative selection	9532317
224289483	224289506	1	-	27869803	HPAFII	viability after 15 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.8239004264045209	[448]	[139,133,NaN]	-9	hSpCas9	negative selection	9614759
224294319	224294342	1	+	27869803	HPAFII	viability after 15 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-6.510636803821355	[559]	[13,1,NaN]	-9	hSpCas9	negative selection	9614762
224303803	224303826	1	-	27869803	HPAFII	viability after 15 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	0.03049198375065859	[202]	[191,241,NaN]	0	hSpCas9	negative selection	9614763
224304800	224304823	1	-	27869803	HPAFII	viability after 15 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-3.4964035060913403	[170]	[27,8,NaN]	-9	hSpCas9	negative selection	9614764
224308091	224308114	1	-	27869803	HPAFII	viability after 15 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-1.7171848395509857	[470]	[214,115,NaN]	-9	hSpCas9	negative selection	9614765
224330052	224330075	1	+	27869803	HPAFII	viability after 15 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.0183379739126373	[240]	[154,110,NaN]	-7	hSpCas9	negative selection	9614766
224289483	224289506	1	-	27869803	ASPC1	viability after 36 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.1488493088086102	[1385]	[320,261,108]	-8	hSpCas9	negative selection	9697208
224294319	224294342	1	+	27869803	ASPC1	viability after 36 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-1.6615035746090725	[1222]	[144,224,54]	-9	hSpCas9	negative selection	9697211
224303803	224303826	1	-	27869803	ASPC1	viability after 36 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-0.6206518314830884	[356]	[168,58,35]	-6	hSpCas9	negative selection	9697212
224304800	224304823	1	-	27869803	ASPC1	viability after 36 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.4368417346580773	[442]	[134,27,24]	-8	hSpCas9	negative selection	9697213
224308091	224308114	1	-	27869803	ASPC1	viability after 36 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-0.6902228802722721	[1068]	[411,253,83]	-6	hSpCas9	negative selection	9697214
224330052	224330075	1	+	27869803	ASPC1	viability after 36 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-1.3076444796787263	[508]	[72,105,42]	-8	hSpCas9	negative selection	9697215
224289483	224289506	1	-	27869803	PATU8988S	viability after 35 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.1169794778566817	[1245]	[174,287,NaN]	-8	hSpCas9	negative selection	9779657
224294319	224294342	1	+	27869803	PATU8988S	viability after 35 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-8.315978874272307	[1185]	[0,1,NaN]	-9	hSpCas9	negative selection	9779660
224303803	224303826	1	-	27869803	PATU8988S	viability after 35 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-2.967695741435401	[290]	[6,22,NaN]	-9	hSpCas9	negative selection	9779661
224304800	224304823	1	-	27869803	PATU8988S	viability after 35 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-1.8787542698469886	[310]	[59,7,NaN]	-9	hSpCas9	negative selection	9779662
224308091	224308114	1	-	27869803	PATU8988S	viability after 35 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-1.712525862536206	[910]	[90,132,NaN]	-8	hSpCas9	negative selection	9779663
224330052	224330075	1	+	27869803	PATU8988S	viability after 35 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-0.3201966382458094	[444]	[165,120,NaN]	-3	hSpCas9	negative selection	9779664
224289483	224289506	1	-	27869803	PATU8988S	viability after 31 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.5361118721919644	[1245]	[147,200,NaN]	-8	hSpCas9	negative selection	9862106
224294319	224294342	1	+	27869803	PATU8988S	viability after 31 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-5.286351656179468	[1185]	[1,24,NaN]	-9	hSpCas9	negative selection	9862109
224303803	224303826	1	-	27869803	PATU8988S	viability after 31 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-1.2285559472163003	[290]	[34,67,NaN]	-8	hSpCas9	negative selection	9862110
224304800	224304823	1	-	27869803	PATU8988S	viability after 31 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-2.310578251533828	[310]	[13,38,NaN]	-9	hSpCas9	negative selection	9862111
224308091	224308114	1	-	27869803	PATU8988S	viability after 31 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-1.3706349481266544	[910]	[132,149,NaN]	-8	hSpCas9	negative selection	9862112
224330052	224330075	1	+	27869803	PATU8988S	viability after 31 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-0.7497385897679281	[444]	[134,67,NaN]	-7	hSpCas9	negative selection	9862113
224289483	224289506	1	-	27869803	HPAFII	viability after 35 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.503066517294708	[448]	[114,40,NaN]	-7	hSpCas9	negative selection	9944555
224294319	224294342	1	+	27869803	HPAFII	viability after 35 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-6.402267584079403	[559]	[0,5,NaN]	-9	hSpCas9	negative selection	9944558
224303803	224303826	1	-	27869803	HPAFII	viability after 35 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-0.1705732547130409	[202]	[0,192,NaN]	-1	hSpCas9	negative selection	9944559
224304800	224304823	1	-	27869803	HPAFII	viability after 35 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-6.435763961889223	[170]	[0,0,NaN]	-9	hSpCas9	negative selection	9944560
224308091	224308114	1	-	27869803	HPAFII	viability after 35 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-4.250221146283649	[470]	[12,11,NaN]	-9	hSpCas9	negative selection	9944561
224330052	224330075	1	+	27869803	HPAFII	viability after 35 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-0.30611728416168155	[240]	[45,157,NaN]	-2	hSpCas9	negative selection	9944562
224289483	224289506	1	-	27869803	HPAFII	viability after 31 days	TGAGCCCACTTCTGAAACACAGG	NVL	ENSG00000143748	-1.3812237171736217	[448]	[101,90,NaN]	-7	hSpCas9	negative selection	10027004
224294319	224294342	1	+	27869803	HPAFII	viability after 31 days	TTCCCGCACGTCTCAAAGCAGGG	NVL	ENSG00000143748	-5.443627552311661	[559]	[0,13,NaN]	-9	hSpCas9	negative selection	10027007
224303803	224303826	1	-	27869803	HPAFII	viability after 31 days	CCCGGAGGTGTACCACCACCTGG	NVL	ENSG00000143748	-0.18296522445923408	[202]	[18,188,NaN]	-1	hSpCas9	negative selection	10027008
224304800	224304823	1	-	27869803	HPAFII	viability after 31 days	TGTTTACCAGCTAAAGCCAGGGG	NVL	ENSG00000143748	-6.58448131521064	[170]	[0,0,NaN]	-9	hSpCas9	negative selection	10027009
224308091	224308114	1	-	27869803	HPAFII	viability after 31 days	CCTGCCAAAGATTCTGAAGGAGG	NVL	ENSG00000143748	-3.034665296109491	[470]	[37,25,NaN]	-9	hSpCas9	negative selection	10027010
224330052	224330075	1	+	27869803	HPAFII	viability after 31 days	AGCGGTGCAGAATACACACCTGG	NVL	ENSG00000143748	-0.4972417193517868	[240]	[35,160,NaN]	-3	hSpCas9	negative selection	10027011
224236504	224236527	1	+	28162770	P31FUJ	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-1.424100856649258	[152]	[66]	-7	hSpCas9	negative selection	10203915
224286036	224286059	1	+	28162770	P31FUJ	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-2.2141865262470315	[307]	[77]	-8	hSpCas9	negative selection	10203916
224303818	224303841	1	-	28162770	P31FUJ	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.009451500053067	[429]	[250]	-6	hSpCas9	negative selection	10203917
224303770	224303793	1	+	28162770	P31FUJ	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-4.266225205951828	[130]	[7]	-9	hSpCas9	negative selection	10203918
224289509	224289532	1	-	28162770	P31FUJ	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-1.9848746909707933	[127]	[37]	-8	hSpCas9	negative selection	10203919
224233212	224233235	1	-	28162770	P31FUJ	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-2.7946810920224934	[247]	[41]	-9	hSpCas9	negative selection	10203920
224304755	224304778	1	-	28162770	P31FUJ	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-2.95526822888547	[461]	[69]	-9	hSpCas9	negative selection	10203921
224303745	224303768	1	+	28162770	P31FUJ	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-1.2328022044143785	[213]	[106]	-7	hSpCas9	negative selection	10203922
224300561	224300584	1	-	28162770	P31FUJ	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.7005811657651957	[64]	[46]	-5	hSpCas9	negative selection	10203923
224287783	224287806	1	-	28162770	P31FUJ	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-4.095298680664444	[159]	[10]	-9	hSpCas9	negative selection	10203924
224236504	224236527	1	+	28162770	TF1	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10373281
224286036	224286059	1	+	28162770	TF1	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10373282
224303818	224303841	1	-	28162770	TF1	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10373283
224303770	224303793	1	+	28162770	TF1	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10373284
224289509	224289532	1	-	28162770	TF1	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10373285
224233212	224233235	1	-	28162770	TF1	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10373286
224304755	224304778	1	-	28162770	TF1	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10373287
224303745	224303768	1	+	28162770	TF1	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10373288
224300561	224300584	1	-	28162770	TF1	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10373289
224287783	224287806	1	-	28162770	TF1	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10373290
224236504	224236527	1	+	28162770	SKM1	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-0.7017074643042935	[45]	[49]	-5	hSpCas9	negative selection	10542647
224286036	224286059	1	+	28162770	SKM1	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-1.7264240380397746	[72]	[38]	-8	hSpCas9	negative selection	10542648
224303818	224303841	1	-	28162770	SKM1	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.9824663702152516	[113]	[50]	-8	hSpCas9	negative selection	10542649
224303770	224303793	1	+	28162770	SKM1	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-2.289127708449304	[46]	[16]	-8	hSpCas9	negative selection	10542650
224289509	224289532	1	-	28162770	SKM1	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-1.4069641987431614	[47]	[31]	-7	hSpCas9	negative selection	10542651
224233212	224233235	1	-	28162770	SKM1	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-0.922930606872786	[73]	[68]	-6	hSpCas9	negative selection	10542652
224304755	224304778	1	-	28162770	SKM1	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-3.991926699464318	[116]	[12]	-9	hSpCas9	negative selection	10542653
224303745	224303768	1	+	28162770	SKM1	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-2.2005133212757353	[51]	[19]	-8	hSpCas9	negative selection	10542654
224300561	224300584	1	-	28162770	SKM1	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.6520766965796931	[23]	[26]	-5	hSpCas9	negative selection	10542655
224287783	224287806	1	-	28162770	SKM1	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-3.991926699464318	[35]	[3]	-9	hSpCas9	negative selection	10542656
224236504	224236527	1	+	28162770	SKM1	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-0.7017074643042935	[45]	[49]	-5	hSpCas9	negative selection	10712013
224286036	224286059	1	+	28162770	SKM1	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-1.7264240380397746	[72]	[38]	-8	hSpCas9	negative selection	10712014
224303818	224303841	1	-	28162770	SKM1	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.9824663702152516	[113]	[50]	-8	hSpCas9	negative selection	10712015
224303770	224303793	1	+	28162770	SKM1	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-2.289127708449304	[46]	[16]	-8	hSpCas9	negative selection	10712016
224289509	224289532	1	-	28162770	SKM1	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-1.4069641987431614	[47]	[31]	-7	hSpCas9	negative selection	10712017
224233212	224233235	1	-	28162770	SKM1	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-0.922930606872786	[73]	[68]	-6	hSpCas9	negative selection	10712018
224304755	224304778	1	-	28162770	SKM1	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-3.991926699464318	[116]	[12]	-9	hSpCas9	negative selection	10712019
224303745	224303768	1	+	28162770	SKM1	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-2.2005133212757353	[51]	[19]	-8	hSpCas9	negative selection	10712020
224300561	224300584	1	-	28162770	SKM1	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.6520766965796931	[23]	[26]	-5	hSpCas9	negative selection	10712021
224287783	224287806	1	-	28162770	SKM1	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-3.991926699464318	[35]	[3]	-9	hSpCas9	negative selection	10712022
224236504	224236527	1	+	28162770	PL21	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	0.3764623871297834	[199]	[112]	3	hSpCas9	negative selection	10881379
224286036	224286059	1	+	28162770	PL21	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-1.0237900419855257	[312]	[66]	-6	hSpCas9	negative selection	10881380
224303818	224303841	1	-	28162770	PL21	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-0.4975908163937858	[398]	[122]	-4	hSpCas9	negative selection	10881381
224303770	224303793	1	+	28162770	PL21	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-1.4810382014911392	[185]	[28]	-7	hSpCas9	negative selection	10881382
224289509	224289532	1	-	28162770	PL21	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-2.259292004147977	[153]	[13]	-8	hSpCas9	negative selection	10881383
224233212	224233235	1	-	28162770	PL21	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-0.2841288866123629	[248]	[88]	-2	hSpCas9	negative selection	10881384
224304755	224304778	1	-	28162770	PL21	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-0.46938718149030867	[403]	[126]	-3	hSpCas9	negative selection	10881385
224303745	224303768	1	+	28162770	PL21	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-2.274639968481413	[188]	[16]	-8	hSpCas9	negative selection	10881386
224300561	224300584	1	-	28162770	PL21	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.3213975060902021	[88]	[30]	-2	hSpCas9	negative selection	10881387
224287783	224287806	1	-	28162770	PL21	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-2.9496075050153623	[70]	[3]	-9	hSpCas9	negative selection	10881388
224236504	224236527	1	+	28162770	P31FUJ	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-1.424100856649258	[152]	[66]	-7	hSpCas9	negative selection	11050745
224286036	224286059	1	+	28162770	P31FUJ	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-2.2141865262470315	[307]	[77]	-8	hSpCas9	negative selection	11050746
224303818	224303841	1	-	28162770	P31FUJ	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.009451500053067	[429]	[250]	-6	hSpCas9	negative selection	11050747
224303770	224303793	1	+	28162770	P31FUJ	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-4.266225205951828	[130]	[7]	-9	hSpCas9	negative selection	11050748
224289509	224289532	1	-	28162770	P31FUJ	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-1.9848746909707933	[127]	[37]	-8	hSpCas9	negative selection	11050749
224233212	224233235	1	-	28162770	P31FUJ	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-2.7946810920224934	[247]	[41]	-9	hSpCas9	negative selection	11050750
224304755	224304778	1	-	28162770	P31FUJ	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-2.95526822888547	[461]	[69]	-9	hSpCas9	negative selection	11050751
224303745	224303768	1	+	28162770	P31FUJ	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-1.2328022044143785	[213]	[106]	-7	hSpCas9	negative selection	11050752
224300561	224300584	1	-	28162770	P31FUJ	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.7005811657651957	[64]	[46]	-5	hSpCas9	negative selection	11050753
224287783	224287806	1	-	28162770	P31FUJ	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-4.095298680664444	[159]	[10]	-9	hSpCas9	negative selection	11050754
224236504	224236527	1	+	28162770	OCIAML5	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-1.4121544029461237	[114]	[77]	-7	hSpCas9	negative selection	11220111
224286036	224286059	1	+	28162770	OCIAML5	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-1.327404580410655	[113]	[81]	-6	hSpCas9	negative selection	11220112
224303818	224303841	1	-	28162770	OCIAML5	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.5102780536157918	[201]	[127]	-7	hSpCas9	negative selection	11220113
224303770	224303793	1	+	28162770	OCIAML5	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-2.261457507001699	[84]	[31]	-8	hSpCas9	negative selection	11220114
224289509	224289532	1	-	28162770	OCIAML5	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-1.903905502383615	[84]	[40]	-7	hSpCas9	negative selection	11220115
224233212	224233235	1	-	28162770	OCIAML5	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-1.3331932606006132	[133]	[95]	-6	hSpCas9	negative selection	11220116
224304755	224304778	1	-	28162770	OCIAML5	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-2.214636650248705	[233]	[90]	-8	hSpCas9	negative selection	11220117
224303745	224303768	1	+	28162770	OCIAML5	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-1.2905086744777845	[144]	[106]	-6	hSpCas9	negative selection	11220118
224300561	224300584	1	-	28162770	OCIAML5	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-1.1864856099345562	[57]	[45]	-6	hSpCas9	negative selection	11220119
224287783	224287806	1	-	28162770	OCIAML5	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-7.278331325566095	[85]	[0]	-9	hSpCas9	negative selection	11220120
224236504	224236527	1	+	28162770	EOL1	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-0.6090678491504014	[413]	[142]	-4	hSpCas9	negative selection	11389477
224286036	224286059	1	+	28162770	EOL1	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-1.1927182805992143	[268]	[61]	-7	hSpCas9	negative selection	11389478
224303818	224303841	1	-	28162770	EOL1	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-2.599014184486478	[781]	[67]	-9	hSpCas9	negative selection	11389479
224303770	224303793	1	+	28162770	EOL1	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-1.1837051190814887	[331]	[76]	-7	hSpCas9	negative selection	11389480
224289509	224289532	1	-	28162770	EOL1	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-2.752746609922697	[370]	[28]	-9	hSpCas9	negative selection	11389481
224233212	224233235	1	-	28162770	EOL1	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-0.6504306405779994	[431]	[144]	-5	hSpCas9	negative selection	11389482
224304755	224304778	1	-	28162770	EOL1	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-3.4315960386547406	[511]	[24]	-9	hSpCas9	negative selection	11389483
224303745	224303768	1	+	28162770	EOL1	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-1.7329833551012668	[264]	[41]	-8	hSpCas9	negative selection	11389484
224300561	224300584	1	-	28162770	EOL1	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-5.323379741873051	[75]	[0]	-9	hSpCas9	negative selection	11389485
224287783	224287806	1	-	28162770	EOL1	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-2.245377229871778	[116]	[12]	-8	hSpCas9	negative selection	11389486
224236504	224236527	1	+	28162770	MOLM13	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-2.7471235094262716	[324]	[34]	-8	hSpCas9	negative selection	11558843
224286036	224286059	1	+	28162770	MOLM13	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-4.527595137332928	[318]	[9]	-9	hSpCas9	negative selection	11558844
224303818	224303841	1	-	28162770	MOLM13	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-3.4443346583669805	[541]	[35]	-8	hSpCas9	negative selection	11558845
224303770	224303793	1	+	28162770	MOLM13	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-4.41203416646367	[264]	[8]	-9	hSpCas9	negative selection	11558846
224289509	224289532	1	-	28162770	MOLM13	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-3.3956086185505594	[261]	[17]	-8	hSpCas9	negative selection	11558847
224233212	224233235	1	-	28162770	MOLM13	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-0.27040527309414697	[361]	[216]	-2	hSpCas9	negative selection	11558848
224304755	224304778	1	-	28162770	MOLM13	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-4.425580698301618	[534]	[17]	-9	hSpCas9	negative selection	11558849
224303745	224303768	1	+	28162770	MOLM13	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-2.4421004527228263	[232]	[30]	-8	hSpCas9	negative selection	11558850
224300561	224300584	1	-	28162770	MOLM13	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-4.935832804506431	[126]	[2]	-9	hSpCas9	negative selection	11558851
224287783	224287806	1	-	28162770	MOLM13	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-6.826731367347048	[156]	[0]	-9	hSpCas9	negative selection	11558852
224236504	224236527	1	+	28162770	HEL	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-1.4685445015333878	[228]	[52]	-7	hSpCas9	negative selection	11728209
224286036	224286059	1	+	28162770	HEL	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-3.468106936687933	[310]	[17]	-9	hSpCas9	negative selection	11728210
224303818	224303841	1	-	28162770	HEL	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-2.409349679148097	[563]	[67]	-8	hSpCas9	negative selection	11728211
224303770	224303793	1	+	28162770	HEL	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-4.861881560403195	[226]	[4]	-9	hSpCas9	negative selection	11728212
224289509	224289532	1	-	28162770	HEL	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-2.2913732323431857	[213]	[27]	-8	hSpCas9	negative selection	11728213
224233212	224233235	1	-	28162770	HEL	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-0.272598770930259	[363]	[192]	-2	hSpCas9	negative selection	11728214
224304755	224304778	1	-	28162770	HEL	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-2.097828998846045	[400]	[59]	-8	hSpCas9	negative selection	11728215
224303745	224303768	1	+	28162770	HEL	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-2.7722986672784873	[159]	[14]	-8	hSpCas9	negative selection	11728216
224300561	224300584	1	-	28162770	HEL	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	0.5018762961605073	[85]	[77]	4	hSpCas9	negative selection	11728217
224287783	224287806	1	-	28162770	HEL	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-2.9201973623908	[129]	[10]	-8	hSpCas9	negative selection	11728218
224236504	224236527	1	+	28162770	MV411	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-1.0051694836006804	[192]	[80]	-6	hSpCas9	negative selection	11897575
224286036	224286059	1	+	28162770	MV411	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-1.3511998868354576	[211]	[69]	-7	hSpCas9	negative selection	11897576
224303818	224303841	1	-	28162770	MV411	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.9108728217568216	[432]	[96]	-8	hSpCas9	negative selection	11897577
224303770	224303793	1	+	28162770	MV411	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-1.7800431856393317	[158]	[38]	-8	hSpCas9	negative selection	11897578
224289509	224289532	1	-	28162770	MV411	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-1.8579154493634533	[141]	[32]	-8	hSpCas9	negative selection	11897579
224233212	224233235	1	-	28162770	MV411	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-1.6739526145208583	[249]	[65]	-7	hSpCas9	negative selection	11897580
224304755	224304778	1	-	28162770	MV411	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-2.051872241442568	[442]	[89]	-8	hSpCas9	negative selection	11897581
224303745	224303768	1	+	28162770	MV411	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-1.3946688570419896	[102]	[32]	-7	hSpCas9	negative selection	11897582
224300561	224300584	1	-	28162770	MV411	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.05212273107613252	[63]	[51]	0	hSpCas9	negative selection	11897583
224287783	224287806	1	-	28162770	MV411	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-3.811456138270793	[99]	[5]	-9	hSpCas9	negative selection	11897584
224236504	224236527	1	+	28162770	MONOMAC1	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-2.096509971105589	[96]	[25]	-9	hSpCas9	negative selection	12066941
224286036	224286059	1	+	28162770	MONOMAC1	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-0.5335623181598741	[148]	[117]	-4	hSpCas9	negative selection	12066942
224303818	224303841	1	-	28162770	MONOMAC1	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.5924455395894648	[291]	[110]	-8	hSpCas9	negative selection	12066943
224303770	224303793	1	+	28162770	MONOMAC1	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-2.5682926543104845	[118]	[22]	-9	hSpCas9	negative selection	12066944
224289509	224289532	1	-	28162770	MONOMAC1	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-1.6683425659851427	[121]	[43]	-8	hSpCas9	negative selection	12066945
224233212	224233235	1	-	28162770	MONOMAC1	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-1.9123073701264408	[219]	[66]	-8	hSpCas9	negative selection	12066946
224304755	224304778	1	-	28162770	MONOMAC1	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-1.9675550009367864	[231]	[67]	-8	hSpCas9	negative selection	12066947
224303745	224303768	1	+	28162770	MONOMAC1	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-1.7550323001804407	[105]	[35]	-8	hSpCas9	negative selection	12066948
224300561	224300584	1	-	28162770	MONOMAC1	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-0.07504632268094324	[33]	[36]	0	hSpCas9	negative selection	12066949
224287783	224287806	1	-	28162770	MONOMAC1	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-2.641821689732449	[48]	[8]	-9	hSpCas9	negative selection	12066950
224236504	224236527	1	+	28162770	OCIAML2	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	-1.622632918687211	[34]	[62]	-7	hSpCas9	negative selection	12236307
224286036	224286059	1	+	28162770	OCIAML2	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-2.1811232080471763	[44]	[54]	-8	hSpCas9	negative selection	12236308
224303818	224303841	1	-	28162770	OCIAML2	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-2.3881676650501884	[67]	[71]	-8	hSpCas9	negative selection	12236309
224303770	224303793	1	+	28162770	OCIAML2	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-2.674163219327293	[37]	[32]	-9	hSpCas9	negative selection	12236310
224289509	224289532	1	-	28162770	OCIAML2	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-2.8185531286624683	[27]	[21]	-9	hSpCas9	negative selection	12236311
224233212	224233235	1	-	28162770	OCIAML2	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-2.0345307104354875	[67]	[91]	-8	hSpCas9	negative selection	12236312
224304755	224304778	1	-	28162770	OCIAML2	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-2.6632749031845573	[63]	[55]	-9	hSpCas9	negative selection	12236313
224303745	224303768	1	+	28162770	OCIAML2	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-1.3503355915244497	[22]	[49]	-7	hSpCas9	negative selection	12236314
224300561	224300584	1	-	28162770	OCIAML2	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	-3.3007048237998493	[15]	[8]	-9	hSpCas9	negative selection	12236315
224287783	224287806	1	-	28162770	OCIAML2	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-3.7925579201295236	[14]	[5]	-9	hSpCas9	negative selection	12236316
224236504	224236527	1	+	28162770	OCIAML3	viability	ACGTATAGCAATCACAGCGAAGG	NVL	ENSG00000143748	0.4520047574326731	[53]	[222]	4	hSpCas9	negative selection	12405673
224286036	224286059	1	+	28162770	OCIAML3	viability	AGAGTCTTCCCACAGCCAGGAGG	NVL	ENSG00000143748	-1.639095529852701	[64]	[62]	-8	hSpCas9	negative selection	12405674
224303818	224303841	1	-	28162770	OCIAML3	viability	CATACACATGCGTCACCCGGAGG	NVL	ENSG00000143748	-1.2650591177590285	[81]	[102]	-7	hSpCas9	negative selection	12405675
224303770	224303793	1	+	28162770	OCIAML3	viability	CATGAAGGAGAACTCCACGAGGG	NVL	ENSG00000143748	-2.4967104389692483	[42]	[22]	-9	hSpCas9	negative selection	12405676
224289509	224289532	1	-	28162770	OCIAML3	viability	GGAGTCCAGGAGGAAAGGCTGGG	NVL	ENSG00000143748	-2.617854382278531	[60]	[29]	-9	hSpCas9	negative selection	12405677
224233212	224233235	1	-	28162770	OCIAML3	viability	GAAATGGCAAGACAGAAGAGTGG	NVL	ENSG00000143748	-0.5645638624316811	[96]	[197]	-4	hSpCas9	negative selection	12405678
224304755	224304778	1	-	28162770	OCIAML3	viability	GTGAAGTTTGAAGATGTGGGAGG	NVL	ENSG00000143748	-2.6692957676284004	[117]	[55]	-9	hSpCas9	negative selection	12405679
224303745	224303768	1	+	28162770	OCIAML3	viability	AATGTCTTCCCACAGCCTGGTGG	NVL	ENSG00000143748	-1.871541615853072	[39]	[32]	-8	hSpCas9	negative selection	12405680
224300561	224300584	1	-	28162770	OCIAML3	viability	AGAACTATTTGAGCAAGCTGTGG	NVL	ENSG00000143748	1.9758479680067849	[7]	[94]	9	hSpCas9	negative selection	12405681
224287783	224287806	1	-	28162770	OCIAML3	viability	CATTAGAGAGGAGCTCACCATGG	NVL	ENSG00000143748	-6.594007640324163	[31]	[0]	-9	hSpCas9	negative selection	12405682