Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4734
• Symbol:Nedd4
• Description:NEDD4 E3 ubiquitin protein ligase

DataSource: http://genomecrispr.dkfz.de/#!/results/Nedd4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
55860709	55860732	15	-	26472758	Jiyoye	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.5167998726803714	[75]	[81]	4	hSpCas9	negative selection	107549
55840485	55840508	15	+	26472758	Jiyoye	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	-0.8544921885640144	[210]	[87]	-5	hSpCas9	negative selection	107550
55850601	55850624	15	+	26472758	Jiyoye	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-0.3380696904248994	[232]	[138]	-2	hSpCas9	negative selection	107551
55850530	55850553	15	+	26472758	Jiyoye	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	0.29321919220878756	[78]	[72]	2	hSpCas9	negative selection	107552
55848544	55848567	15	-	26472758	Jiyoye	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	-0.08381097100626911	[259]	[184]	0	hSpCas9	negative selection	107553
55842061	55842084	15	-	26472758	Jiyoye	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.5384199147841261	[209]	[229]	4	hSpCas9	negative selection	107554
55860489	55860512	15	+	26472758	Jiyoye	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.20287810017811314	[231]	[151]	-1	hSpCas9	negative selection	107555
55856130	55856153	15	-	26472758	Jiyoye	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	1.4440121496862448	[57]	[118]	8	hSpCas9	negative selection	107556
55856123	55856146	15	+	26472758	Jiyoye	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	-0.6136832233917908	[208]	[102]	-4	hSpCas9	negative selection	107557
55852412	55852435	15	+	26472758	Jiyoye	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	2.281644499422014	[5]	[21]	9	hSpCas9	negative selection	107558
55860709	55860732	15	-	26472758	KBM7	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.6810347073015899	[556,328]	[377,280]	7	hSpCas9	negative selection	298667
55840485	55840508	15	+	26472758	KBM7	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	0.1922333293683882	[484,486]	[216,302]	2	hSpCas9	negative selection	298668
55850601	55850624	15	+	26472758	KBM7	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-0.09342032828933328	[771,442]	[249,271]	-1	hSpCas9	negative selection	298669
55850530	55850553	15	+	26472758	KBM7	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	-0.35910514494448287	[239,225]	[55,111]	-3	hSpCas9	negative selection	298670
55848544	55848567	15	-	26472758	KBM7	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	0.12901867390978505	[1009,752]	[699,223]	1	hSpCas9	negative selection	298671
55842061	55842084	15	-	26472758	KBM7	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.48213371964404406	[931,589]	[523,460]	5	hSpCas9	negative selection	298672
55860489	55860512	15	+	26472758	KBM7	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.34902995230888245	[1142,898]	[484,274]	-3	hSpCas9	negative selection	298673
55856130	55856153	15	-	26472758	KBM7	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.04686172191459248	[498,670]	[321,260]	0	hSpCas9	negative selection	298674
55856123	55856146	15	+	26472758	KBM7	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	-0.1591162963836647	[672,525]	[240,258]	-1	hSpCas9	negative selection	298675
55852412	55852435	15	+	26472758	KBM7	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	0.7442361326328513	[62,85]	[61,57]	7	hSpCas9	negative selection	298676
55860709	55860732	15	-	26472758	Raji	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.154689250151956	[239]	[61]	1	hSpCas9	negative selection	489785
55840485	55840508	15	+	26472758	Raji	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	0.6120582471371196	[233]	[82]	6	hSpCas9	negative selection	489786
55850601	55850624	15	+	26472758	Raji	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-1.1701504401553093	[319]	[32]	-7	hSpCas9	negative selection	489787
55850530	55850553	15	+	26472758	Raji	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	0.029381023372326287	[151]	[35]	0	hSpCas9	negative selection	489788
55848544	55848567	15	-	26472758	Raji	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	0.08123124751763067	[500]	[122]	0	hSpCas9	negative selection	489789
55842061	55842084	15	-	26472758	Raji	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.3495305747335695	[486]	[143]	3	hSpCas9	negative selection	489790
55860489	55860512	15	+	26472758	Raji	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.027042784847326695	[561]	[127]	0	hSpCas9	negative selection	489791
55856130	55856153	15	-	26472758	Raji	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.1898456955655725	[271]	[71]	1	hSpCas9	negative selection	489792
55856123	55856146	15	+	26472758	Raji	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.17633088909109096	[285]	[74]	1	hSpCas9	negative selection	489793
55852412	55852435	15	+	26472758	Raji	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	0.22868983159573297	[113]	[30]	2	hSpCas9	negative selection	489794
55860709	55860732	15	-	26472758	K562	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.13719777085255452	[362]	[336]	1	hSpCas9	negative selection	680903
55840485	55840508	15	+	26472758	K562	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	0.16445042296303158	[611]	[578]	1	hSpCas9	negative selection	680904
55850601	55850624	15	+	26472758	K562	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-1.7555812723335529	[683]	[170]	-7	hSpCas9	negative selection	680905
55850530	55850553	15	+	26472758	K562	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	-0.7835956485031497	[207]	[101]	-4	hSpCas9	negative selection	680906
55848544	55848567	15	-	26472758	K562	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	-0.19144499881519994	[720]	[532]	-1	hSpCas9	negative selection	680907
55842061	55842084	15	-	26472758	K562	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.4116655331747072	[658]	[739]	3	hSpCas9	negative selection	680908
55860489	55860512	15	+	26472758	K562	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.8274841932150053	[760]	[1139]	7	hSpCas9	negative selection	680909
55856130	55856153	15	-	26472758	K562	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.6712333947216443	[548]	[737]	5	hSpCas9	negative selection	680910
55856123	55856146	15	+	26472758	K562	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.1692939890681986	[472]	[448]	1	hSpCas9	negative selection	680911
55852412	55852435	15	+	26472758	K562	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	0.6714288686113665	[89]	[120]	5	hSpCas9	negative selection	680912
55850655	55850678	15	-	26627737	DLD1	viability	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.8423535927155135	[763]	[479,372,428]	7	hSpCas9	negative selection	791076
55852512	55852535	15	-	26627737	DLD1	viability	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.5825040967621906	[169]	[66,19,20]	-5	hSpCas9	negative selection	791077
55860489	55860512	15	+	26627737	DLD1	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.23860247431047607	[535]	[230,252,122]	2	hSpCas9	negative selection	791078
55860694	55860717	15	+	26627737	DLD1	viability	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	1.040492189749569	[100]	[31,44,109]	8	hSpCas9	negative selection	791079
55916191	55916214	15	+	26627737	DLD1	viability	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.5086709993442182	[377]	[95,256,156]	5	hSpCas9	negative selection	791080
55993537	55993560	15	-	26627737	DLD1	viability	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	0.49920154993177024	[724]	[264,281,399]	5	hSpCas9	negative selection	791081
55850655	55850678	15	-	26627737	GBM cells	viability after 5 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.6524504485461592	[276]	[289,176]	8	hSpCas9	negative selection	873391
55852512	55852535	15	-	26627737	GBM cells	viability after 5 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.19086989002198873	[106]	[60,69]	3	hSpCas9	negative selection	873392
55860489	55860512	15	+	26627737	GBM cells	viability after 5 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.21627506297671417	[416]	[170,213]	-3	hSpCas9	negative selection	873393
55860694	55860717	15	+	26627737	GBM cells	viability after 5 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	-0.6261771698580723	[58]	[24,15]	-7	hSpCas9	negative selection	873394
55916191	55916214	15	+	26627737	GBM cells	viability after 5 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.4543504233036698	[180]	[151,113]	6	hSpCas9	negative selection	873395
55993537	55993560	15	-	26627737	GBM cells	viability after 5 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-0.044317029181816764	[298]	[176,133]	0	hSpCas9	negative selection	873396
55850655	55850678	15	-	26627737	GBM cells	viability after 13 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.7100127617479592	[276]	[300,200]	8	hSpCas9	negative selection	955706
55852512	55852535	15	-	26627737	GBM cells	viability after 13 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.9464748267875245	[106]	[80,136]	9	hSpCas9	negative selection	955707
55860489	55860512	15	+	26627737	GBM cells	viability after 13 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.06021317100321888	[416]	[236,234]	0	hSpCas9	negative selection	955708
55860694	55860717	15	+	26627737	GBM cells	viability after 13 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	0.35856364203233393	[58]	[61,23]	4	hSpCas9	negative selection	955709
55916191	55916214	15	+	26627737	GBM cells	viability after 13 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-0.23302248856555619	[180]	[98,70]	-3	hSpCas9	negative selection	955710
55993537	55993560	15	-	26627737	GBM cells	viability after 13 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	0.04637203909640081	[298]	[118,206]	0	hSpCas9	negative selection	955711
55850655	55850678	15	-	26627737	GBM cells	viability after 21 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.09939793619090212	[276]	[155,165]	1	hSpCas9	negative selection	1038021
55852512	55852535	15	-	26627737	GBM cells	viability after 21 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.9484094118673858	[106]	[107,115]	8	hSpCas9	negative selection	1038022
55860489	55860512	15	+	26627737	GBM cells	viability after 21 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.6808618452523498	[416]	[405,323]	7	hSpCas9	negative selection	1038023
55860694	55860717	15	+	26627737	GBM cells	viability after 21 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	-1.1996420971842308	[58]	[14,12]	-7	hSpCas9	negative selection	1038024
55916191	55916214	15	+	26627737	GBM cells	viability after 21 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-0.005720829589677734	[180]	[110,85]	0	hSpCas9	negative selection	1038025
55993537	55993560	15	-	26627737	GBM cells	viability after 21 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-0.028971161831106457	[298]	[165,152]	0	hSpCas9	negative selection	1038026
55850655	55850678	15	-	26627737	RPE1	viability after 9 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.27800712748129847	[1077]	[544,233]	2	hSpCas9	negative selection	1120336
55852512	55852535	15	-	26627737	RPE1	viability after 9 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.7793536242493805	[482]	[152,396]	5	hSpCas9	negative selection	1120337
55860489	55860512	15	+	26627737	RPE1	viability after 9 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.4673241655008158	[988]	[338,542]	3	hSpCas9	negative selection	1120338
55860694	55860717	15	+	26627737	RPE1	viability after 9 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	0.03207783901635297	[223]	[48,100]	0	hSpCas9	negative selection	1120339
55916191	55916214	15	+	26627737	RPE1	viability after 9 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	1.7522030629496363	[157]	[108,240]	8	hSpCas9	negative selection	1120340
55993537	55993560	15	-	26627737	RPE1	viability after 9 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	0.6570685624401869	[927]	[427,496]	4	hSpCas9	negative selection	1120341
55850655	55850678	15	-	26627737	RPE1	viability after 12 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.013205456608356925	[1077]	[352,227]	0	hSpCas9	negative selection	1202651
55852512	55852535	15	-	26627737	RPE1	viability after 12 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.3522001888404419	[482]	[72,131]	-2	hSpCas9	negative selection	1202652
55860489	55860512	15	+	26627737	RPE1	viability after 12 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.8138282119897191	[988]	[452,481]	5	hSpCas9	negative selection	1202653
55860694	55860717	15	+	26627737	RPE1	viability after 12 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	0.380486328449793	[223]	[38,119]	2	hSpCas9	negative selection	1202654
55916191	55916214	15	+	26627737	RPE1	viability after 12 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	2.0207506605888357	[157]	[146,198]	8	hSpCas9	negative selection	1202655
55993537	55993560	15	-	26627737	RPE1	viability after 12 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	1.2311276719682624	[927]	[679,484]	7	hSpCas9	negative selection	1202656
55850655	55850678	15	-	26627737	RPE1	viability after 15 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.3179096051344135	[1077]	[485,277]	2	hSpCas9	negative selection	1284966
55852512	55852535	15	-	26627737	RPE1	viability after 15 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.4290056470541667	[482]	[186,180]	2	hSpCas9	negative selection	1284967
55860489	55860512	15	+	26627737	RPE1	viability after 15 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.6741387778285275	[988]	[535,359]	4	hSpCas9	negative selection	1284968
55860694	55860717	15	+	26627737	RPE1	viability after 15 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	0.5045051885410141	[223]	[95,83]	3	hSpCas9	negative selection	1284969
55916191	55916214	15	+	26627737	RPE1	viability after 15 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	2.6305078788051817	[157]	[345,209]	9	hSpCas9	negative selection	1284970
55993537	55993560	15	-	26627737	RPE1	viability after 15 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	1.861123991520407	[927]	[999,908]	8	hSpCas9	negative selection	1284971
55850655	55850678	15	-	26627737	RPE1	viability after 18 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	-0.20865918448462845	[1077]	[287,212]	-1	hSpCas9	negative selection	1367281
55852512	55852535	15	-	26627737	RPE1	viability after 18 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.6470184010950177	[482]	[119,293]	4	hSpCas9	negative selection	1367282
55860489	55860512	15	+	26627737	RPE1	viability after 18 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.7570677213335613	[988]	[394,510]	4	hSpCas9	negative selection	1367283
55860694	55860717	15	+	26627737	RPE1	viability after 18 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	-0.07285077312306898	[223]	[12,104]	0	hSpCas9	negative selection	1367284
55916191	55916214	15	+	26627737	RPE1	viability after 18 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	2.9024639609351714	[157]	[327,308]	9	hSpCas9	negative selection	1367285
55993537	55993560	15	-	26627737	RPE1	viability after 18 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	2.4631254552583224	[927]	[1524,1226]	9	hSpCas9	negative selection	1367286
55850655	55850678	15	-	26627737	HeLa	viability after 8 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.5267702191150413	[435]	[361,344,141]	5	hSpCas9	negative selection	1449596
55852512	55852535	15	-	26627737	HeLa	viability after 8 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.5908330938223891	[192]	[95,51,29]	-5	hSpCas9	negative selection	1449597
55860489	55860512	15	+	26627737	HeLa	viability after 8 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-1.5851280553534741	[417]	[14,83,71]	-9	hSpCas9	negative selection	1449598
55860694	55860717	15	+	26627737	HeLa	viability after 8 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	-3.542068575897724	[209]	[21,1,2]	-9	hSpCas9	negative selection	1449599
55916191	55916214	15	+	26627737	HeLa	viability after 8 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.5550145474533763	[170]	[121,117,91]	5	hSpCas9	negative selection	1449600
55993537	55993560	15	-	26627737	HeLa	viability after 8 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-0.8994015623734551	[668]	[143,201,121]	-7	hSpCas9	negative selection	1449601
55850655	55850678	15	-	26627737	HeLa	viability after 12 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.8136982709958879	[435]	[532,197,237]	6	hSpCas9	negative selection	1531911
55852512	55852535	15	-	26627737	HeLa	viability after 12 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.5851029004386064	[192]	[54,48,55]	-5	hSpCas9	negative selection	1531912
55860489	55860512	15	+	26627737	HeLa	viability after 12 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.4418062663282069	[417]	[56,178,137]	-4	hSpCas9	negative selection	1531913
55860694	55860717	15	+	26627737	HeLa	viability after 12 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	-0.4796935578026851	[209]	[97,40,50]	-4	hSpCas9	negative selection	1531914
55916191	55916214	15	+	26627737	HeLa	viability after 12 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.01706895800293906	[170]	[63,64,85]	0	hSpCas9	negative selection	1531915
55993537	55993560	15	-	26627737	HeLa	viability after 12 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-0.7275780505264812	[668]	[266,117,123]	-6	hSpCas9	negative selection	1531916
55850655	55850678	15	-	26627737	HeLa	viability after 15 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	-0.060573297491952505	[435]	[93,193,227]	0	hSpCas9	negative selection	1614226
55852512	55852535	15	-	26627737	HeLa	viability after 15 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-2.122021526712631	[192]	[16,8,28]	-9	hSpCas9	negative selection	1614227
55860489	55860512	15	+	26627737	HeLa	viability after 15 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.28694753035950404	[417]	[131,269,222]	2	hSpCas9	negative selection	1614228
55860694	55860717	15	+	26627737	HeLa	viability after 15 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	-1.213319826459009	[209]	[48,17,43]	-8	hSpCas9	negative selection	1614229
55916191	55916214	15	+	26627737	HeLa	viability after 15 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-0.8528932327014049	[170]	[60,31,20]	-6	hSpCas9	negative selection	1614230
55993537	55993560	15	-	26627737	HeLa	viability after 15 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-1.1703712857551711	[668]	[125,199,29]	-8	hSpCas9	negative selection	1614231
55850655	55850678	15	-	26627737	HeLa	viability after 18 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	-0.0701069358038761	[435]	[62,157,227]	0	hSpCas9	negative selection	1696541
55852512	55852535	15	-	26627737	HeLa	viability after 18 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-2.1965743298936355	[192]	[9,6,28]	-9	hSpCas9	negative selection	1696542
55860489	55860512	15	+	26627737	HeLa	viability after 18 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.29754978090518763	[417]	[91,222,222]	2	hSpCas9	negative selection	1696543
55860694	55860717	15	+	26627737	HeLa	viability after 18 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	-1.1697489884635917	[209]	[34,14,43]	-8	hSpCas9	negative selection	1696544
55916191	55916214	15	+	26627737	HeLa	viability after 18 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-0.8553291938899583	[170]	[37,29,20]	-6	hSpCas9	negative selection	1696545
55993537	55993560	15	-	26627737	HeLa	viability after 18 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-1.1853180647847195	[668]	[80,166,29]	-8	hSpCas9	negative selection	1696546
55850655	55850678	15	-	26627737	HCT116	viability after 6 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	-1.1997257908891448	[908]	[116,31]	-6	hSpCas9	negative selection	1778856
55852512	55852535	15	-	26627737	HCT116	viability after 6 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.47248785382339653	[160]	[34,8]	-3	hSpCas9	negative selection	1778857
55860489	55860512	15	+	26627737	HCT116	viability after 6 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.7353799351831289	[1040]	[751,7]	4	hSpCas9	negative selection	1778858
55860694	55860717	15	+	26627737	HCT116	viability after 6 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	-2.78963581066468	[216]	[2,5]	-9	hSpCas9	negative selection	1778859
55916191	55916214	15	+	26627737	HCT116	viability after 6 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	1.4528729038097996	[416]	[85,230]	7	hSpCas9	negative selection	1778860
55993537	55993560	15	-	26627737	HCT116	viability after 6 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	0.2986891974807747	[1144]	[38,321]	1	hSpCas9	negative selection	1778861
55850655	55850678	15	-	26627737	HCT116	viability after 8 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	-0.05389488943678755	[444]	[192,288,225]	0	hSpCas9	negative selection	1861171
55852512	55852535	15	-	26627737	HCT116	viability after 8 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.6988277036950241	[75]	[80,41,80]	6	hSpCas9	negative selection	1861172
55860489	55860512	15	+	26627737	HCT116	viability after 8 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.5404645848146349	[574]	[200,297,154]	-6	hSpCas9	negative selection	1861173
55860694	55860717	15	+	26627737	HCT116	viability after 8 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	0.16764007331386344	[27]	[16,18,15]	2	hSpCas9	negative selection	1861174
55916191	55916214	15	+	26627737	HCT116	viability after 8 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-0.9992449659932221	[414]	[126,149,66]	-8	hSpCas9	negative selection	1861175
55993537	55993560	15	-	26627737	HCT116	viability after 8 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	0.06438234123028308	[384]	[327,168,170]	0	hSpCas9	negative selection	1861176
55850655	55850678	15	-	26627737	HCT116	viability after 9 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	-0.7571080253073357	[908]	[132,151]	-5	hSpCas9	negative selection	1943486
55852512	55852535	15	-	26627737	HCT116	viability after 9 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.19169758144039672	[160]	[71,30]	1	hSpCas9	negative selection	1943487
55860489	55860512	15	+	26627737	HCT116	viability after 9 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.19836283745366357	[1040]	[433,227]	1	hSpCas9	negative selection	1943488
55860694	55860717	15	+	26627737	HCT116	viability after 9 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	1.4864942159108436	[216]	[53,247]	8	hSpCas9	negative selection	1943489
55916191	55916214	15	+	26627737	HCT116	viability after 9 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-0.993184412082633	[416]	[46,62]	-6	hSpCas9	negative selection	1943490
55993537	55993560	15	-	26627737	HCT116	viability after 9 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-0.08063185606107393	[1144]	[163,387]	0	hSpCas9	negative selection	1943491
55850655	55850678	15	-	26627737	HCT116	viability after 12 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.14229697630392568	[444]	[229,349,198]	1	hSpCas9	negative selection	2025801
55852512	55852535	15	-	26627737	HCT116	viability after 12 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.7029222114328157	[75]	[32,70,93]	6	hSpCas9	negative selection	2025802
55860489	55860512	15	+	26627737	HCT116	viability after 12 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.45701793291401144	[574]	[145,264,256]	-5	hSpCas9	negative selection	2025803
55860694	55860717	15	+	26627737	HCT116	viability after 12 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	0.8955804143972195	[27]	[41,33,4]	7	hSpCas9	negative selection	2025804
55916191	55916214	15	+	26627737	HCT116	viability after 12 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-0.5736139554353104	[414]	[159,127,149]	-6	hSpCas9	negative selection	2025805
55993537	55993560	15	-	26627737	HCT116	viability after 12 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	0.1915636810923031	[384]	[233,151,304]	2	hSpCas9	negative selection	2025806
55850655	55850678	15	-	26627737	HCT116	viability after 15 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.20132519600790222	[444]	[212,392,265]	2	hSpCas9	negative selection	2108116
55852512	55852535	15	-	26627737	HCT116	viability after 15 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.19818693362614326	[75]	[12,52,44]	-2	hSpCas9	negative selection	2108117
55860489	55860512	15	+	26627737	HCT116	viability after 15 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-1.2556866356438041	[574]	[122,149,139]	-8	hSpCas9	negative selection	2108118
55860694	55860717	15	+	26627737	HCT116	viability after 15 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	1.8572747284736033	[27]	[66,62,45]	9	hSpCas9	negative selection	2108119
55916191	55916214	15	+	26627737	HCT116	viability after 15 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-1.0178229476265421	[414]	[146,118,90]	-7	hSpCas9	negative selection	2108120
55993537	55993560	15	-	26627737	HCT116	viability after 15 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-0.07743606287681604	[384]	[305,258,76]	-1	hSpCas9	negative selection	2108121
55850655	55850678	15	-	26627737	HCT116	viability after 18 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.12792685356824351	[444]	[105,255,346]	1	hSpCas9	negative selection	2190431
55852512	55852535	15	-	26627737	HCT116	viability after 18 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.19451997222569828	[75]	[18,26,82]	1	hSpCas9	negative selection	2190432
55860489	55860512	15	+	26627737	HCT116	viability after 18 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-1.120107168911896	[574]	[36,110,241]	-7	hSpCas9	negative selection	2190433
55860694	55860717	15	+	26627737	HCT116	viability after 18 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	0.796304586891043	[27]	[65,1,2]	6	hSpCas9	negative selection	2190434
55916191	55916214	15	+	26627737	HCT116	viability after 18 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-0.8350465866685489	[414]	[167,75,94]	-6	hSpCas9	negative selection	2190435
55993537	55993560	15	-	26627737	HCT116	viability after 18 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	0.267534690537588	[384]	[457,77,141]	2	hSpCas9	negative selection	2190436
55860750	55860773	15	+	24336569	HL60	viability	TGCCATTCTCAGCATCTGTTAGG	NEDD4	ENSG00000069869	-0.0031478569658694826	[483]	[1021]	0	hSpCas9	negative selection	2279677
55862945	55862968	15	+	24336569	HL60	viability	AGATTCATGGTTTACATAATAGG	NEDD4	ENSG00000069869	0.4805250636879206	[210]	[622]	4	hSpCas9	negative selection	2279678
55862956	55862979	15	+	24336569	HL60	viability	TTACATAATAGGTCCTTCCAAGG	NEDD4	ENSG00000069869	0.36483761216679833	[290]	[792]	3	hSpCas9	negative selection	2279679
55862969	55862992	15	-	24336569	HL60	viability	AGAGGCAGGATATCCTTGGAAGG	NEDD4	ENSG00000069869	1.7539547398465842	[159]	[1141]	9	hSpCas9	negative selection	2279680
55862982	55863005	15	+	24336569	HL60	viability	TCCTGCCTCTCTTCCCACCCTGG	NEDD4	ENSG00000069869	-0.3183218839036166	[851]	[1445]	-3	hSpCas9	negative selection	2279681
55862987	55863010	15	-	24336569	HL60	viability	TACCTCCAGGGTGGGAAGAGAGG	NEDD4	ENSG00000069869	0.26737272346349383	[732]	[1866]	2	hSpCas9	negative selection	2279682
55862995	55863018	15	-	24336569	HL60	viability	TTCTCCTCTACCTCCAGGGTGGG	NEDD4	ENSG00000069869	-4.147052442256473	[359]	[42]	-9	hSpCas9	negative selection	2279683
55863000	55863023	15	-	24336569	HL60	viability	GAACCTTCTCCTCTACCTCCAGG	NEDD4	ENSG00000069869	-0.752841353167526	[386]	[485]	-6	hSpCas9	negative selection	2279684
55863019	55863042	15	+	24336569	HL60	viability	GTTCTTGTTGTTGCTGCAAATGG	NEDD4	ENSG00000069869	0.2678103013997369	[647]	[1650]	2	hSpCas9	negative selection	2279685
55863033	55863056	15	+	24336569	HL60	viability	TGCAAATGGCAAGCAGCATCTGG	NEDD4	ENSG00000069869	0.2879427044253491	[806]	[2084]	2	hSpCas9	negative selection	2279686
55860750	55860773	15	+	24336569	KBM7	viability	TGCCATTCTCAGCATCTGTTAGG	NEDD4	ENSG00000069869	0.735461304683688	[437]	[1988]	6	hSpCas9	negative selection	2346854
55862945	55862968	15	+	24336569	KBM7	viability	AGATTCATGGTTTACATAATAGG	NEDD4	ENSG00000069869	0.43126836187783296	[328]	[1209]	4	hSpCas9	negative selection	2346855
55862956	55862979	15	+	24336569	KBM7	viability	TTACATAATAGGTCCTTCCAAGG	NEDD4	ENSG00000069869	0.7085400053683993	[244]	[1091]	6	hSpCas9	negative selection	2346856
55862969	55862992	15	-	24336569	KBM7	viability	AGAGGCAGGATATCCTTGGAAGG	NEDD4	ENSG00000069869	0.3296662144107748	[331]	[1137]	3	hSpCas9	negative selection	2346857
55862982	55863005	15	+	24336569	KBM7	viability	TCCTGCCTCTCTTCCCACCCTGG	NEDD4	ENSG00000069869	0.366865150295041	[376]	[1325]	3	hSpCas9	negative selection	2346858
55862987	55863010	15	-	24336569	KBM7	viability	TACCTCCAGGGTGGGAAGAGAGG	NEDD4	ENSG00000069869	-0.7876256971332354	[1261]	[1993]	-6	hSpCas9	negative selection	2346859
55862995	55863018	15	-	24336569	KBM7	viability	TTCTCCTCTACCTCCAGGGTGGG	NEDD4	ENSG00000069869	-1.5201829455057223	[162]	[154]	-7	hSpCas9	negative selection	2346860
55863000	55863023	15	-	24336569	KBM7	viability	GAACCTTCTCCTCTACCTCCAGG	NEDD4	ENSG00000069869	0.6426699237538018	[212]	[906]	6	hSpCas9	negative selection	2346861
55863019	55863042	15	+	24336569	KBM7	viability	GTTCTTGTTGTTGCTGCAAATGG	NEDD4	ENSG00000069869	0.8326692197994285	[603]	[2933]	7	hSpCas9	negative selection	2346862
55863033	55863056	15	+	24336569	KBM7	viability	TGCAAATGGCAAGCAGCATCTGG	NEDD4	ENSG00000069869	0.32445418711283636	[885]	[3025]	3	hSpCas9	negative selection	2346863
55926813	55926836	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCCCAGCACTTAAG	NEDD4	ENSG00000069869	-0.9680503266497309	[486,330]	[14,78]	-5	dCas9-VP64	positive selection	2398730
55875333	55875356	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGTCTTGCTCTGTCACCCTAG	NEDD4	ENSG00000069869	-0.3535447244958476	[9,7]	[1,0]	-2	dCas9-VP64	positive selection	2410910
55897001	55897024	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCACTCTGTTGCCCAGACCGG	NEDD4	ENSG00000069869	2.6118589352134576	[275,130]	[385,150]	8	dCas9-VP64	positive selection	2414713
55904895	55904918	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCTCCATGTTGGTCAGGCTAG	NEDD4	ENSG00000069869	-2.2958931667653815	[393,165]	[8,14]	-9	dCas9-VP64	positive selection	2417320
55881240	55881263	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTGAGGCAGGAGAATTGCCGG	NEDD4	ENSG00000069869	1.7637175755419017	[20,19]	[24,4]	6	dCas9-VP64	positive selection	2454717
55844845	55844868	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCATTCAGGCTGGAGTGCAGTGG	NEDD4	ENSG00000069869	0.7741136303930765	[29,7]	[9,2]	3	dCas9-VP64	positive selection	2455177
55954597	55954620	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCGCAACCTCCGCCTCCCAG	NEDD4	ENSG00000069869	-0.9705266312095737	[543,439]	[39,70]	-6	dCas9-VP64	positive selection	2469153
55921495	55921518	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTATTTTTAGTAGAGACGCAG	NEDD4	ENSG00000069869	4.010018042841921	[201,101]	[623,445]	9	dCas9-VP64	positive selection	2473516
55917291	55917314	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGTCGGCTGGAGAAAGTATAGG	NEDD4	ENSG00000069869	7.528658778278193	[66,121]	[33,8041]	9	dCas9-VP64	positive selection	2474670
55917317	55917340	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCACTAATATTTTTACCCATAGG	NEDD4	ENSG00000069869	-0.8038030306501738	[663,618]	[42,121]	-4	dCas9-VP64	positive selection	2474671
55917303	55917326	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TATTAGTGGGCAAAGTCGGCTGG	NEDD4	ENSG00000069869	2.7979404032753052	[251,132]	[184,412]	8	dCas9-VP64	positive selection	2474672
55926813	55926836	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCCCAGCACTTAAG	NEDD4	ENSG00000069869	0.18483027177666878	[252,653]	[84,243]	1	dCas9-VP64	positive selection	2493985
55875333	55875356	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGTCTTGCTCTGTCACCCTAG	NEDD4	ENSG00000069869	1.2662700076660216	[113,78]	[31,116]	7	dCas9-VP64	positive selection	2506165
55897001	55897024	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCACTCTGTTGCCCAGACCGG	NEDD4	ENSG00000069869	-0.18468441030242128	[164,170]	[47,47]	-2	dCas9-VP64	positive selection	2509968
55904895	55904918	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCTCCATGTTGGTCAGGCTAG	NEDD4	ENSG00000069869	0.6223741115754664	[126,133]	[38,89]	4	dCas9-VP64	positive selection	2512575
55881240	55881263	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTGAGGCAGGAGAATTGCCGG	NEDD4	ENSG00000069869	-0.8253509621016023	[144,7]	[19,7]	-7	dCas9-VP64	positive selection	2549972
55844845	55844868	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCATTCAGGCTGGAGTGCAGTGG	NEDD4	ENSG00000069869	0.6857223168869587	[164,83]	[44,84]	5	dCas9-VP64	positive selection	2550432
55954597	55954620	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCGCAACCTCCGCCTCCCAG	NEDD4	ENSG00000069869	0.25678800348412345	[582,649]	[296,187]	2	dCas9-VP64	positive selection	2564408
55921495	55921518	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTATTTTTAGTAGAGACGCAG	NEDD4	ENSG00000069869	1.087060795387326	[282,711]	[216,460]	7	dCas9-VP64	positive selection	2568771
55917291	55917314	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGTCGGCTGGAGAAAGTATAGG	NEDD4	ENSG00000069869	3.2312867830431085	[96,380]	[31,1375]	9	dCas9-VP64	positive selection	2569925
55917317	55917340	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCACTAATATTTTTACCCATAGG	NEDD4	ENSG00000069869	0.5378576338097265	[383,354]	[92,252]	4	dCas9-VP64	positive selection	2569926
55917303	55917326	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TATTAGTGGGCAAAGTCGGCTGG	NEDD4	ENSG00000069869	0.8719142926775865	[63,212]	[49,111]	6	dCas9-VP64	positive selection	2569927
55863019	55863042	15	+	27260157	DLD1	viability	GTTCTTGTTGTTGCTGCAAATGG	NEDD4	ENSG00000069869	0.233890800440534	[]	[]	4	hSpCas9	negative selection	2575599
55862982	55863005	15	+	27260157	DLD1	viability	TCCTGCCTCTCTTCCCACCCTGG	NEDD4	ENSG00000069869	-1.00119496115178	[]	[]	-7	hSpCas9	negative selection	2577397
55916886	55916909	15	-	27260157	DLD1	viability	AGCTGCTTCTAGCCTGTCTACGG	NEDD4	ENSG00000069869	0.629006243760477	[]	[]	8	hSpCas9	negative selection	2578910
55862987	55863010	15	-	27260157	DLD1	viability	TACCTCCAGGGTGGGAAGAGAGG	NEDD4	ENSG00000069869	-2.25073898403279	[]	[]	-9	hSpCas9	negative selection	2581085
55916380	55916403	15	+	27260157	DLD1	viability	AGGCTACCACTACAAATGGCTGG	NEDD4	ENSG00000069869	0.250150069432523	[]	[]	4	hSpCas9	negative selection	2582107
55862969	55862992	15	-	27260157	DLD1	viability	AGAGGCAGGATATCCTTGGAAGG	NEDD4	ENSG00000069869	-0.0874167697498968	[]	[]	0	hSpCas9	negative selection	2584914
55862995	55863018	15	-	27260157	DLD1	viability	TTCTCCTCTACCTCCAGGGTGGG	NEDD4	ENSG00000069869	-0.869999777653704	[]	[]	-6	hSpCas9	negative selection	2585016
55863033	55863056	15	+	27260157	DLD1	viability	TGCAAATGGCAAGCAGCATCTGG	NEDD4	ENSG00000069869	-0.364170550845057	[]	[]	-3	hSpCas9	negative selection	2606828
55916175	55916198	15	-	27260157	DLD1	viability	CCAATAGAAGTGTGCCAAACAGG	NEDD4	ENSG00000069869	0.738745109414872	[]	[]	8	hSpCas9	negative selection	2608183
55993537	55993560	15	-	27260157	DLD1	viability	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-2.24412779505689	[]	[]	-9	hSpCas9	negative selection	2612588
55860750	55860773	15	+	27260157	DLD1	viability	TGCCATTCTCAGCATCTGTTAGG	NEDD4	ENSG00000069869	0.333771239865205	[]	[]	4	hSpCas9	negative selection	2614279
55916750	55916773	15	-	27260157	DLD1	viability	AGAAACCTCCGGAGATGACTTGG	NEDD4	ENSG00000069869	-0.113069078334344	[]	[]	-1	hSpCas9	negative selection	2616473
55916191	55916214	15	+	27260157	DLD1	viability	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.0283673845788363	[]	[]	0	hSpCas9	negative selection	2616635
55966489	55966512	15	-	27260157	DLD1	viability	CGGAATAGGCCTTGCCAAGAAGG	NEDD4	ENSG00000069869	1.11824060342371	[]	[]	9	hSpCas9	negative selection	2617009
55993552	55993575	15	-	27260157	DLD1	viability	TTGCTGGAAGCGTTCGGAAATGG	NEDD4	ENSG00000069869	-0.0530523310411306	[]	[]	0	hSpCas9	negative selection	2620634
55917100	55917123	15	-	27260157	DLD1	viability	GAGCTCAGCTTAAAGGTCGCTGG	NEDD4	ENSG00000069869	-0.422232062773107	[]	[]	-3	hSpCas9	negative selection	2621178
55862945	55862968	15	+	27260157	DLD1	viability	AGATTCATGGTTTACATAATAGG	NEDD4	ENSG00000069869	-0.847676461360231	[]	[]	-6	hSpCas9	negative selection	2621181
55916652	55916675	15	+	27260157	DLD1	viability	CGGAGCTAGTGCAGTCTGTCTGG	NEDD4	ENSG00000069869	0.489467033457881	[]	[]	8	hSpCas9	negative selection	2623656
55862956	55862979	15	+	27260157	DLD1	viability	TTACATAATAGGTCCTTCCAAGG	NEDD4	ENSG00000069869	0.394444073636025	[]	[]	4	hSpCas9	negative selection	2644016
55863000	55863023	15	-	27260157	DLD1	viability	GAACCTTCTCCTCTACCTCCAGG	NEDD4	ENSG00000069869	-0.0503582410859498	[]	[]	0	hSpCas9	negative selection	2645671
55863019	55863042	15	+	27260157	HT1080	viability	GTTCTTGTTGTTGCTGCAAATGG	NEDD4	ENSG00000069869	0.667855538010994	[]	[]	6	hSpCas9	negative selection	2651729
55862982	55863005	15	+	27260157	HT1080	viability	TCCTGCCTCTCTTCCCACCCTGG	NEDD4	ENSG00000069869	-2.16009692217827	[]	[]	-9	hSpCas9	negative selection	2653527
55916886	55916909	15	-	27260157	HT1080	viability	AGCTGCTTCTAGCCTGTCTACGG	NEDD4	ENSG00000069869	0.994381074572401	[]	[]	8	hSpCas9	negative selection	2655040
55862987	55863010	15	-	27260157	HT1080	viability	TACCTCCAGGGTGGGAAGAGAGG	NEDD4	ENSG00000069869	-2.48240928470933	[]	[]	-9	hSpCas9	negative selection	2657215
55916380	55916403	15	+	27260157	HT1080	viability	AGGCTACCACTACAAATGGCTGG	NEDD4	ENSG00000069869	0.528498165942661	[]	[]	4	hSpCas9	negative selection	2658237
55862969	55862992	15	-	27260157	HT1080	viability	AGAGGCAGGATATCCTTGGAAGG	NEDD4	ENSG00000069869	0.136105452480465	[]	[]	1	hSpCas9	negative selection	2661044
55862995	55863018	15	-	27260157	HT1080	viability	TTCTCCTCTACCTCCAGGGTGGG	NEDD4	ENSG00000069869	-0.399186209390275	[]	[]	-7	hSpCas9	negative selection	2661146
55863033	55863056	15	+	27260157	HT1080	viability	TGCAAATGGCAAGCAGCATCTGG	NEDD4	ENSG00000069869	0.00550877739406369	[]	[]	0	hSpCas9	negative selection	2682958
55916175	55916198	15	-	27260157	HT1080	viability	CCAATAGAAGTGTGCCAAACAGG	NEDD4	ENSG00000069869	0.663421691521194	[]	[]	6	hSpCas9	negative selection	2684313
55993537	55993560	15	-	27260157	HT1080	viability	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-2.19962242734425	[]	[]	-9	hSpCas9	negative selection	2688718
55860750	55860773	15	+	27260157	HT1080	viability	TGCCATTCTCAGCATCTGTTAGG	NEDD4	ENSG00000069869	-0.172762605078905	[]	[]	0	hSpCas9	negative selection	2690409
55916750	55916773	15	-	27260157	HT1080	viability	AGAAACCTCCGGAGATGACTTGG	NEDD4	ENSG00000069869	-0.542097181534654	[]	[]	-7	hSpCas9	negative selection	2692603
55916191	55916214	15	+	27260157	HT1080	viability	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-0.0780132308573268	[]	[]	0	hSpCas9	negative selection	2692765
55966489	55966512	15	-	27260157	HT1080	viability	CGGAATAGGCCTTGCCAAGAAGG	NEDD4	ENSG00000069869	1.1177380582718	[]	[]	8	hSpCas9	negative selection	2693139
55993552	55993575	15	-	27260157	HT1080	viability	TTGCTGGAAGCGTTCGGAAATGG	NEDD4	ENSG00000069869	-0.129986339395524	[]	[]	0	hSpCas9	negative selection	2696764
55917100	55917123	15	-	27260157	HT1080	viability	GAGCTCAGCTTAAAGGTCGCTGG	NEDD4	ENSG00000069869	0.740075090234061	[]	[]	6	hSpCas9	negative selection	2697308
55862945	55862968	15	+	27260157	HT1080	viability	AGATTCATGGTTTACATAATAGG	NEDD4	ENSG00000069869	-0.896959389257905	[]	[]	-8	hSpCas9	negative selection	2697311
55916652	55916675	15	+	27260157	HT1080	viability	CGGAGCTAGTGCAGTCTGTCTGG	NEDD4	ENSG00000069869	-0.0749316264746088	[]	[]	0	hSpCas9	negative selection	2699786
55862956	55862979	15	+	27260157	HT1080	viability	TTACATAATAGGTCCTTCCAAGG	NEDD4	ENSG00000069869	0.405019880379136	[]	[]	3	hSpCas9	negative selection	2720146
55863000	55863023	15	-	27260157	HT1080	viability	GAACCTTCTCCTCTACCTCCAGG	NEDD4	ENSG00000069869	-0.629339293979104	[]	[]	-8	hSpCas9	negative selection	2721801
55863019	55863042	15	+	27260157	MKN45	viability	GTTCTTGTTGTTGCTGCAAATGG	NEDD4	ENSG00000069869	-0.0594707632781574	[]	[]	0	hSpCas9	negative selection	2727859
55862982	55863005	15	+	27260157	MKN45	viability	TCCTGCCTCTCTTCCCACCCTGG	NEDD4	ENSG00000069869	-2.03190734575812	[]	[]	-9	hSpCas9	negative selection	2729657
55916886	55916909	15	-	27260157	MKN45	viability	AGCTGCTTCTAGCCTGTCTACGG	NEDD4	ENSG00000069869	1.54665999163532	[]	[]	9	hSpCas9	negative selection	2731170
55862987	55863010	15	-	27260157	MKN45	viability	TACCTCCAGGGTGGGAAGAGAGG	NEDD4	ENSG00000069869	-1.98652300815771	[]	[]	-9	hSpCas9	negative selection	2733345
55916380	55916403	15	+	27260157	MKN45	viability	AGGCTACCACTACAAATGGCTGG	NEDD4	ENSG00000069869	-0.554578882332726	[]	[]	-6	hSpCas9	negative selection	2734367
55862969	55862992	15	-	27260157	MKN45	viability	AGAGGCAGGATATCCTTGGAAGG	NEDD4	ENSG00000069869	-0.634195986152808	[]	[]	-6	hSpCas9	negative selection	2737174
55862995	55863018	15	-	27260157	MKN45	viability	TTCTCCTCTACCTCCAGGGTGGG	NEDD4	ENSG00000069869	0.408972970584367	[]	[]	6	hSpCas9	negative selection	2737276
55863033	55863056	15	+	27260157	MKN45	viability	TGCAAATGGCAAGCAGCATCTGG	NEDD4	ENSG00000069869	0.540237537477903	[]	[]	7	hSpCas9	negative selection	2759088
55916175	55916198	15	-	27260157	MKN45	viability	CCAATAGAAGTGTGCCAAACAGG	NEDD4	ENSG00000069869	1.60976152504299	[]	[]	9	hSpCas9	negative selection	2760443
55993537	55993560	15	-	27260157	MKN45	viability	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-2.45098679168126	[]	[]	-9	hSpCas9	negative selection	2764848
55860750	55860773	15	+	27260157	MKN45	viability	TGCCATTCTCAGCATCTGTTAGG	NEDD4	ENSG00000069869	0.668925907659596	[]	[]	7	hSpCas9	negative selection	2766539
55916750	55916773	15	-	27260157	MKN45	viability	AGAAACCTCCGGAGATGACTTGG	NEDD4	ENSG00000069869	0.730729220172793	[]	[]	7	hSpCas9	negative selection	2768733
55916191	55916214	15	+	27260157	MKN45	viability	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.391239528036358	[]	[]	6	hSpCas9	negative selection	2768895
55966489	55966512	15	-	27260157	MKN45	viability	CGGAATAGGCCTTGCCAAGAAGG	NEDD4	ENSG00000069869	0.6192640177815	[]	[]	7	hSpCas9	negative selection	2769269
55993552	55993575	15	-	27260157	MKN45	viability	TTGCTGGAAGCGTTCGGAAATGG	NEDD4	ENSG00000069869	-0.350190162965251	[]	[]	-1	hSpCas9	negative selection	2772894
55917100	55917123	15	-	27260157	MKN45	viability	GAGCTCAGCTTAAAGGTCGCTGG	NEDD4	ENSG00000069869	-0.69314039822395	[]	[]	-7	hSpCas9	negative selection	2773438
55862945	55862968	15	+	27260157	MKN45	viability	AGATTCATGGTTTACATAATAGG	NEDD4	ENSG00000069869	-0.629705021880527	[]	[]	-6	hSpCas9	negative selection	2773441
55916652	55916675	15	+	27260157	MKN45	viability	CGGAGCTAGTGCAGTCTGTCTGG	NEDD4	ENSG00000069869	-0.248143139519141	[]	[]	-1	hSpCas9	negative selection	2775916
55862956	55862979	15	+	27260157	MKN45	viability	TTACATAATAGGTCCTTCCAAGG	NEDD4	ENSG00000069869	0.666611206068042	[]	[]	7	hSpCas9	negative selection	2796276
55863000	55863023	15	-	27260157	MKN45	viability	GAACCTTCTCCTCTACCTCCAGG	NEDD4	ENSG00000069869	-0.694477834125643	[]	[]	-7	hSpCas9	negative selection	2797931
55863019	55863042	15	+	27260157	RKO	viability	GTTCTTGTTGTTGCTGCAAATGG	NEDD4	ENSG00000069869	0.0653216310232489	[]	[]	0	hSpCas9	negative selection	2803989
55862982	55863005	15	+	27260157	RKO	viability	TCCTGCCTCTCTTCCCACCCTGG	NEDD4	ENSG00000069869	-2.23122643756473	[]	[]	-9	hSpCas9	negative selection	2805787
55916886	55916909	15	-	27260157	RKO	viability	AGCTGCTTCTAGCCTGTCTACGG	NEDD4	ENSG00000069869	1.32669587896762	[]	[]	9	hSpCas9	negative selection	2807300
55862987	55863010	15	-	27260157	RKO	viability	TACCTCCAGGGTGGGAAGAGAGG	NEDD4	ENSG00000069869	-2.60992548503722	[]	[]	-9	hSpCas9	negative selection	2809475
55916380	55916403	15	+	27260157	RKO	viability	AGGCTACCACTACAAATGGCTGG	NEDD4	ENSG00000069869	0.667407712573633	[]	[]	7	hSpCas9	negative selection	2810497
55862969	55862992	15	-	27260157	RKO	viability	AGAGGCAGGATATCCTTGGAAGG	NEDD4	ENSG00000069869	-0.0440785332349306	[]	[]	0	hSpCas9	negative selection	2813304
55862995	55863018	15	-	27260157	RKO	viability	TTCTCCTCTACCTCCAGGGTGGG	NEDD4	ENSG00000069869	-1.23191318845934	[]	[]	-8	hSpCas9	negative selection	2813406
55863033	55863056	15	+	27260157	RKO	viability	TGCAAATGGCAAGCAGCATCTGG	NEDD4	ENSG00000069869	-0.426768205830283	[]	[]	-6	hSpCas9	negative selection	2835218
55916175	55916198	15	-	27260157	RKO	viability	CCAATAGAAGTGTGCCAAACAGG	NEDD4	ENSG00000069869	0.587963967884535	[]	[]	3	hSpCas9	negative selection	2836573
55993537	55993560	15	-	27260157	RKO	viability	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-1.88698157362734	[]	[]	-9	hSpCas9	negative selection	2840978
55860750	55860773	15	+	27260157	RKO	viability	TGCCATTCTCAGCATCTGTTAGG	NEDD4	ENSG00000069869	0.166136927841735	[]	[]	0	hSpCas9	negative selection	2842669
55916750	55916773	15	-	27260157	RKO	viability	AGAAACCTCCGGAGATGACTTGG	NEDD4	ENSG00000069869	0.408597371758802	[]	[]	2	hSpCas9	negative selection	2844863
55916191	55916214	15	+	27260157	RKO	viability	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-0.355788279932944	[]	[]	-6	hSpCas9	negative selection	2845025
55966489	55966512	15	-	27260157	RKO	viability	CGGAATAGGCCTTGCCAAGAAGG	NEDD4	ENSG00000069869	0.196494584155401	[]	[]	1	hSpCas9	negative selection	2845399
55993552	55993575	15	-	27260157	RKO	viability	TTGCTGGAAGCGTTCGGAAATGG	NEDD4	ENSG00000069869	-0.0261066253812351	[]	[]	0	hSpCas9	negative selection	2849024
55917100	55917123	15	-	27260157	RKO	viability	GAGCTCAGCTTAAAGGTCGCTGG	NEDD4	ENSG00000069869	0.520919298464989	[]	[]	2	hSpCas9	negative selection	2849568
55862945	55862968	15	+	27260157	RKO	viability	AGATTCATGGTTTACATAATAGG	NEDD4	ENSG00000069869	-0.383899585565995	[]	[]	-6	hSpCas9	negative selection	2849571
55916652	55916675	15	+	27260157	RKO	viability	CGGAGCTAGTGCAGTCTGTCTGG	NEDD4	ENSG00000069869	0.759908074690407	[]	[]	8	hSpCas9	negative selection	2852046
55862956	55862979	15	+	27260157	RKO	viability	TTACATAATAGGTCCTTCCAAGG	NEDD4	ENSG00000069869	0.915550279319427	[]	[]	8	hSpCas9	negative selection	2872406
55863000	55863023	15	-	27260157	RKO	viability	GAACCTTCTCCTCTACCTCCAGG	NEDD4	ENSG00000069869	-0.639219841801595	[]	[]	-7	hSpCas9	negative selection	2874061
55863019	55863042	15	+	27260157	SF268	viability	GTTCTTGTTGTTGCTGCAAATGG	NEDD4	ENSG00000069869	0.357567099789733	[]	[]	4	hSpCas9	negative selection	2880119
55862982	55863005	15	+	27260157	SF268	viability	TCCTGCCTCTCTTCCCACCCTGG	NEDD4	ENSG00000069869	-2.81165478302954	[]	[]	-9	hSpCas9	negative selection	2881917
55916886	55916909	15	-	27260157	SF268	viability	AGCTGCTTCTAGCCTGTCTACGG	NEDD4	ENSG00000069869	1.32891033855831	[]	[]	9	hSpCas9	negative selection	2883430
55862987	55863010	15	-	27260157	SF268	viability	TACCTCCAGGGTGGGAAGAGAGG	NEDD4	ENSG00000069869	-2.16021128655265	[]	[]	-9	hSpCas9	negative selection	2885605
55916380	55916403	15	+	27260157	SF268	viability	AGGCTACCACTACAAATGGCTGG	NEDD4	ENSG00000069869	-0.555749340319174	[]	[]	-4	hSpCas9	negative selection	2886627
55862969	55862992	15	-	27260157	SF268	viability	AGAGGCAGGATATCCTTGGAAGG	NEDD4	ENSG00000069869	-0.33852029244517	[]	[]	-3	hSpCas9	negative selection	2889434
55862995	55863018	15	-	27260157	SF268	viability	TTCTCCTCTACCTCCAGGGTGGG	NEDD4	ENSG00000069869	-0.73050474150966	[]	[]	-5	hSpCas9	negative selection	2889536
55863033	55863056	15	+	27260157	SF268	viability	TGCAAATGGCAAGCAGCATCTGG	NEDD4	ENSG00000069869	-1.58000110652961	[]	[]	-8	hSpCas9	negative selection	2911348
55916175	55916198	15	-	27260157	SF268	viability	CCAATAGAAGTGTGCCAAACAGG	NEDD4	ENSG00000069869	0.540265215674287	[]	[]	8	hSpCas9	negative selection	2912703
55993537	55993560	15	-	27260157	SF268	viability	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-1.89833696816017	[]	[]	-8	hSpCas9	negative selection	2917108
55860750	55860773	15	+	27260157	SF268	viability	TGCCATTCTCAGCATCTGTTAGG	NEDD4	ENSG00000069869	0.371238963755951	[]	[]	4	hSpCas9	negative selection	2918799
55916750	55916773	15	-	27260157	SF268	viability	AGAAACCTCCGGAGATGACTTGG	NEDD4	ENSG00000069869	0.577583142985285	[]	[]	8	hSpCas9	negative selection	2920993
55916191	55916214	15	+	27260157	SF268	viability	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.134465256711002	[]	[]	0	hSpCas9	negative selection	2921155
55966489	55966512	15	-	27260157	SF268	viability	CGGAATAGGCCTTGCCAAGAAGG	NEDD4	ENSG00000069869	0.230985828425504	[]	[]	3	hSpCas9	negative selection	2921529
55993552	55993575	15	-	27260157	SF268	viability	TTGCTGGAAGCGTTCGGAAATGG	NEDD4	ENSG00000069869	0.150403038640346	[]	[]	0	hSpCas9	negative selection	2925154
55917100	55917123	15	-	27260157	SF268	viability	GAGCTCAGCTTAAAGGTCGCTGG	NEDD4	ENSG00000069869	0.282147798223912	[]	[]	4	hSpCas9	negative selection	2925698
55862945	55862968	15	+	27260157	SF268	viability	AGATTCATGGTTTACATAATAGG	NEDD4	ENSG00000069869	-0.959034566564412	[]	[]	-6	hSpCas9	negative selection	2925701
55916652	55916675	15	+	27260157	SF268	viability	CGGAGCTAGTGCAGTCTGTCTGG	NEDD4	ENSG00000069869	0.0264805729027026	[]	[]	0	hSpCas9	negative selection	2928176
55862956	55862979	15	+	27260157	SF268	viability	TTACATAATAGGTCCTTCCAAGG	NEDD4	ENSG00000069869	0.646260615240255	[]	[]	8	hSpCas9	negative selection	2948536
55863000	55863023	15	-	27260157	SF268	viability	GAACCTTCTCCTCTACCTCCAGG	NEDD4	ENSG00000069869	0.261444513531286	[]	[]	4	hSpCas9	negative selection	2950191
55852512	55852535	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.011477439317715943	[4,4]	[4,3]	0	hSpCas9	positive selection	3005193
55924645	55924668	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTGTTTGACGAAAACCGATTGG	NEDD4	ENSG00000069869	-0.2490356693209067	[1,2]	[2,0]	-4	hSpCas9	positive selection	3005194
55862930	55862953	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGAATCTAGAAGAACACAGTGG	NEDD4	ENSG00000069869	-0.014658841548953541	[3,2]	[2,2]	0	hSpCas9	positive selection	3005195
55924631	55924654	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACAATATAACTTACCAATCGG	NEDD4	ENSG00000069869	-0.3881011494653118	[5,5]	[4,2]	-5	hSpCas9	positive selection	3005196
55852512	55852535	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.26944383440359665	[4,4]	[4,0]	-4	hSpCas9	positive selection	3073051
55924645	55924668	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTGTTTGACGAAAACCGATTGG	NEDD4	ENSG00000069869	1.213463436845386	[1,1]	[1,5]	9	hSpCas9	positive selection	3073052
55862930	55862953	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGAATCTAGAAGAACACAGTGG	NEDD4	ENSG00000069869	-0.6461873777528383	[3,3]	[0,1]	-8	hSpCas9	positive selection	3073053
55924631	55924654	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACAATATAACTTACCAATCGG	NEDD4	ENSG00000069869	0.2520733840408771	[5,5]	[6,3]	4	hSpCas9	positive selection	3073054
55951383	55951406		+	24336571	A375	resistance to PLX after 7 days	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	-0.06890880360883586	[10,10]	[10,10]	-2	hSpCas9	positive selection	3130242
55848382	55848405		+	24336571	A375	resistance to PLX after 7 days	ATTGCTACATTCTCCAACCGAGG	NEDD4	ENSG00000069869	0.30334534221178827	[10,7]	[13,9]	8	hSpCas9	positive selection	3130243
55846968	55846991		-	24336571	A375	resistance to PLX after 7 days	CCGAAGAAAGTTGAAGAAGCAGG	NEDD4	ENSG00000069869	0.01622238153055955	[4,6]	[5,5]	0	hSpCas9	positive selection	3130244
55993501	55993524		+	24336571	A375	resistance to PLX after 7 days	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.08362112283726847	[12,11]	[11,14]	3	hSpCas9	positive selection	3130245
55847017	55847040		-	24336571	A375	resistance to PLX after 7 days	TAAAGGCAGTGCCCTACTCCAGG	NEDD4	ENSG00000069869	0.12337047605800022	[25,20]	[24,25]	4	hSpCas9	positive selection	3130246
55993540	55993563		-	24336571	A375	resistance to PLX after 7 days	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	-0.011110732824849201	[5,5]	[5,5]	0	hSpCas9	positive selection	3130247
55951397	55951420		-	24336571	A375	resistance to PLX after 7 days	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	-0.09681235691149848	[3,3]	[3,2]	-3	hSpCas9	positive selection	3130249
55951383	55951406		+	24336571	A375	resistance to PLX after 14 days	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.2005250634271999	[5,8]	[2,3]	2	hSpCas9	positive selection	3188035
55848382	55848405		+	24336571	A375	resistance to PLX after 14 days	ATTGCTACATTCTCCAACCGAGG	NEDD4	ENSG00000069869	-0.2763292689926792	[10,9]	[2,3]	-3	hSpCas9	positive selection	3188036
55846968	55846991		-	24336571	A375	resistance to PLX after 14 days	CCGAAGAAAGTTGAAGAAGCAGG	NEDD4	ENSG00000069869	-0.53821723870819	[7,7]	[1,1]	-6	hSpCas9	positive selection	3188037
55993501	55993524		+	24336571	A375	resistance to PLX after 14 days	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.8338571738842706	[12,12]	[11,9]	7	hSpCas9	positive selection	3188038
55847017	55847040		-	24336571	A375	resistance to PLX after 14 days	TAAAGGCAGTGCCCTACTCCAGG	NEDD4	ENSG00000069869	-0.3052676497276372	[22,29]	[8,10]	-3	hSpCas9	positive selection	3188039
55993540	55993563		-	24336571	A375	resistance to PLX after 14 days	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	-0.09205172863252653	[3,9]	[1,2]	-1	hSpCas9	positive selection	3188040
55951397	55951420		-	24336571	A375	resistance to PLX after 14 days	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.5958456508949519	[2,1]	[1,1]	5	hSpCas9	positive selection	3188042
55951383	55951406		+	24336571	A375	viability after 7 days	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.015112074437502232	[11]	[10,10]	0	hSpCas9	negative selection	3245828
55848382	55848405		+	24336571	A375	viability after 7 days	ATTGCTACATTCTCCAACCGAGG	NEDD4	ENSG00000069869	-0.10797658412100214	[10]	[10,7]	-1	hSpCas9	negative selection	3245829
55846968	55846991		-	24336571	A375	viability after 7 days	CCGAAGAAAGTTGAAGAAGCAGG	NEDD4	ENSG00000069869	-0.34496875955745787	[7]	[4,6]	-5	hSpCas9	negative selection	3245830
55993501	55993524		+	24336571	A375	viability after 7 days	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.18285478626525434	[11]	[12,11]	2	hSpCas9	negative selection	3245831
55847017	55847040		-	24336571	A375	viability after 7 days	TAAAGGCAGTGCCCTACTCCAGG	NEDD4	ENSG00000069869	-0.2325104523669418	[28]	[25,20]	-3	hSpCas9	negative selection	3245832
55993540	55993563		-	24336571	A375	viability after 7 days	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.01756294875644593	[5]	[5,5]	0	hSpCas9	negative selection	3245833
55951397	55951420		-	24336571	A375	viability after 7 days	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	-0.23881386978640817	[4]	[3,3]	-3	hSpCas9	negative selection	3245835
55951383	55951406		+	24336571	A375	viability after 14 days	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	-0.49023770142425005	[11]	[5,8]	-5	hSpCas9	negative selection	3303621
55848382	55848405		+	24336571	A375	viability after 14 days	ATTGCTACATTCTCCAACCGAGG	NEDD4	ENSG00000069869	0.01657248024562069	[10]	[10,9]	0	hSpCas9	negative selection	3303622
55846968	55846991		-	24336571	A375	viability after 14 days	CCGAAGAAAGTTGAAGAAGCAGG	NEDD4	ENSG00000069869	0.038134626868692734	[7]	[7,7]	0	hSpCas9	negative selection	3303623
55993501	55993524		+	24336571	A375	viability after 14 days	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.23807239332012065	[11]	[12,12]	3	hSpCas9	negative selection	3303624
55847017	55847040		-	24336571	A375	viability after 14 days	TAAAGGCAGTGCCCTACTCCAGG	NEDD4	ENSG00000069869	-0.036365898972479105	[28]	[22,29]	0	hSpCas9	negative selection	3303625
55993540	55993563		-	24336571	A375	viability after 14 days	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.2055671304176987	[5]	[3,9]	2	hSpCas9	negative selection	3303626
55951397	55951420		-	24336571	A375	viability after 14 days	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	-0.7505600621630129	[4]	[2,1]	-7	hSpCas9	negative selection	3303628
55951397	55951420	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	-0.3201026165899134	[190,190]	[0,0]	-2	hSpCas9	positive selection	3381401
55993501	55993524	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.009398698002249677	[151,151]	[0,0]	0	hSpCas9	positive selection	3381402
55951383	55951406	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.8310614567437372	[85,85]	[0,0]	4	hSpCas9	positive selection	3381403
55852512	55852535	15	-	26780180	HT29	viability (Avana library 4 designs)	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.106404125721803	[]	[]	0	hSpCas9	negative selection	3443025
55924645	55924668	15	-	26780180	HT29	viability (Avana library 4 designs)	AGTGTTTGACGAAAACCGATTGG	NEDD4	ENSG00000069869	1.00408713064646	[]	[]	4	hSpCas9	negative selection	3443026
55862930	55862953	15	-	26780180	HT29	viability (Avana library 4 designs)	ATGAATCTAGAAGAACACAGTGG	NEDD4	ENSG00000069869	1.62964887394384	[]	[]	6	hSpCas9	negative selection	3443027
55924630	55924653	15	+	26780180	HT29	viability (Avana library 4 designs)	GCACAATATAACTTACCAATCGG	NEDD4	ENSG00000069869	-0.565132603079616	[]	[]	-7	hSpCas9	negative selection	3443028
55862930	55862953	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGAATCTAGAAGAACACAGTGG	NEDD4	ENSG00000069869	-6.79041529704891	[]	[]	-6	hSpCas9	negative selection	3534515
55852512	55852535	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.195798897448258	[]	[]	0	hSpCas9	negative selection	3534516
55924645	55924668	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGTTTGACGAAAACCGATTGG	NEDD4	ENSG00000069869	-5.80775829100468	[]	[]	-6	hSpCas9	negative selection	3534517
55924630	55924653	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACAATATAACTTACCAATCGG	NEDD4	ENSG00000069869	-13.436864880401	[]	[]	-8	hSpCas9	negative selection	3534518
55860660	55860683	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGACAACCGAGAGTCTTCCGAGG	NEDD4	ENSG00000069869	2.44200920098167	[]	[]	3	hSpCas9	negative selection	3534519
55860709	55860732	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.700766113826198	[]	[]	1	hSpCas9	negative selection	3534520
55862930	55862953	15	-	26780180	A375	viability (Avana lentiGuide)	ATGAATCTAGAAGAACACAGTGG	NEDD4	ENSG00000069869	-3.72121783620929	[]	[]	-6	hSpCas9	negative selection	3643174
55852512	55852535	15	-	26780180	A375	viability (Avana lentiGuide)	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-1.44148071295802	[]	[]	-2	hSpCas9	negative selection	3643175
55924645	55924668	15	-	26780180	A375	viability (Avana lentiGuide)	AGTGTTTGACGAAAACCGATTGG	NEDD4	ENSG00000069869	3.27505608702333	[]	[]	3	hSpCas9	negative selection	3643176
55924630	55924653	15	+	26780180	A375	viability (Avana lentiGuide)	GCACAATATAACTTACCAATCGG	NEDD4	ENSG00000069869	-3.76947363940355	[]	[]	-6	hSpCas9	negative selection	3643177
55860660	55860683	15	-	26780180	A375	viability (Avana lentiGuide)	TGACAACCGAGAGTCTTCCGAGG	NEDD4	ENSG00000069869	0.408160728752827	[]	[]	0	hSpCas9	negative selection	3643178
55860709	55860732	15	-	26780180	A375	viability (Avana lentiGuide)	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	1.33858118218887	[]	[]	1	hSpCas9	negative selection	3643179
55862930	55862953	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGAATCTAGAAGAACACAGTGG	NEDD4	ENSG00000069869	-0.6690262860343581	[6]	[4,2]	-7	hSpCas9	positive selection	3751833
55852512	55852535	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.3279184910147446	[5]	[4,3]	-5	hSpCas9	positive selection	3751834
55924645	55924668	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGTTTGACGAAAACCGATTGG	NEDD4	ENSG00000069869	-0.4239839522891209	[4]	[3,1]	-6	hSpCas9	positive selection	3751835
55924630	55924653	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACAATATAACTTACCAATCGG	NEDD4	ENSG00000069869	-0.503753239017976	[8]	[5,4]	-6	hSpCas9	positive selection	3751836
55860660	55860683	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGACAACCGAGAGTCTTCCGAGG	NEDD4	ENSG00000069869	-0.14346983024097426	[4]	[4,3]	-2	hSpCas9	positive selection	3751837
55860709	55860732	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	-0.06576465952104067	[5]	[4,4]	-1	hSpCas9	positive selection	3751838
55862930	55862953	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGAATCTAGAAGAACACAGTGG	NEDD4	ENSG00000069869	0.1934434638055199	[4]	[5,3]	5	hSpCas9	positive selection	3860440
55852512	55852535	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.017835016609819787	[6]	[4,5]	0	hSpCas9	positive selection	3860441
55924645	55924668	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGTTTGACGAAAACCGATTGG	NEDD4	ENSG00000069869	-0.06800472064671403	[3]	[1,4]	-1	hSpCas9	positive selection	3860442
55924630	55924653	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACAATATAACTTACCAATCGG	NEDD4	ENSG00000069869	0.36257361550386275	[6]	[7,7]	9	hSpCas9	positive selection	3860443
55860660	55860683	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGACAACCGAGAGTCTTCCGAGG	NEDD4	ENSG00000069869	0.148901400254253	[4]	[4,4]	3	hSpCas9	positive selection	3860444
55860709	55860732	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	-0.022782665468404704	[5]	[3,4]	0	hSpCas9	positive selection	3860445
55951383	55951406	15	+	26780180	A375	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.613290691616611	[]	[]	2	hSpCas9	negative selection	3971756
55873953	55873976	15	+	26780180	A375	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	1.01092401584007	[]	[]	5	hSpCas9	negative selection	3971757
55993501	55993524	15	+	26780180	A375	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	1.45363757442876	[]	[]	8	hSpCas9	negative selection	3971758
55873957	55873980	15	-	26780180	A375	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.554969466869265	[]	[]	1	hSpCas9	negative selection	3971759
55993540	55993563	15	-	26780180	A375	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.924251487554322	[]	[]	4	hSpCas9	negative selection	3971760
55951397	55951420	15	-	26780180	A375	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.293861513487571	[]	[]	0	hSpCas9	negative selection	3971761
55951383	55951406	15	+	26780180	HT29	viability (GeCKOv2 library)	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.41421220828588	[]	[]	1	hSpCas9	negative selection	4079722
55873953	55873976	15	+	26780180	HT29	viability (GeCKOv2 library)	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	1.41816412098917	[]	[]	7	hSpCas9	negative selection	4079723
55993501	55993524	15	+	26780180	HT29	viability (GeCKOv2 library)	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	1.81788652398378	[]	[]	8	hSpCas9	negative selection	4079724
55873957	55873980	15	-	26780180	HT29	viability (GeCKOv2 library)	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.583307580228565	[]	[]	2	hSpCas9	negative selection	4079725
55993540	55993563	15	-	26780180	HT29	viability (GeCKOv2 library)	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	-0.108632342999367	[]	[]	-3	hSpCas9	negative selection	4079726
55951397	55951420	15	-	26780180	HT29	viability (GeCKOv2 library)	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	1.13422881447468	[]	[]	5	hSpCas9	negative selection	4079727
55951383	55951406	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.006115897709520146	[3]	[1,1]	0	hSpCas9	positive selection	4154879
55848382	55848405	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTGCTACATTCTCCAACCGAGG	NEDD4	ENSG00000069869	-0.13666993828974094	[3]	[1,1]	-3	hSpCas9	positive selection	4154880
55846968	55846991	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGAAGAAAGTTGAAGAAGCAGG	NEDD4	ENSG00000069869	-0.4156057494170005	[2]	[0,0]	-8	hSpCas9	positive selection	4154881
55993501	55993524	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.14300954462144727	[3]	[1,3]	3	hSpCas9	positive selection	4154882
55847017	55847040	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAAAGGCAGTGCCCTACTCCAGG	NEDD4	ENSG00000069869	0.05026771137602726	[4]	[3,3]	1	hSpCas9	positive selection	4154883
55993540	55993563	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	-0.1750775348084712	[2]	[1,1]	-4	hSpCas9	positive selection	4154884
55951397	55951420	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	-0.3309116689231838	[1]	[0,0]	-7	hSpCas9	positive selection	4154886
55951383	55951406	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.8015774480089775	[2]	[4,2,1,0]	5	hSpCas9	positive selection	4218901
55848382	55848405	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTGCTACATTCTCCAACCGAGG	NEDD4	ENSG00000069869	-0.39957503401565364	[4]	[0,1,1,0]	-6	hSpCas9	positive selection	4218902
55846968	55846991	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGAAGAAAGTTGAAGAAGCAGG	NEDD4	ENSG00000069869	0.10773378580539728	[1]	[0,1,0,0]	0	hSpCas9	positive selection	4218903
55993501	55993524	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.7605952095803109	[2]	[5,1,3,0]	5	hSpCas9	positive selection	4218904
55847017	55847040	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAAAGGCAGTGCCCTACTCCAGG	NEDD4	ENSG00000069869	0.5071974684090269	[4]	[4,3,3,0]	3	hSpCas9	positive selection	4218905
55993540	55993563	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	1.581246895722518	[1]	[0,0,0,3]	9	hSpCas9	positive selection	4218906
55951397	55951420	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.3789456315533408	[1]	[0,2,1,0]	3	hSpCas9	positive selection	4218908
55993540	55993563	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.6084300237591935	[3]	[3,5]	9	hSpCas9	positive selection	4285257
55873953	55873976	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	-0.7211034249723784	[2]	[1,0]	-9	hSpCas9	positive selection	4285258
55873957	55873980	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	-0.04516335013231677	[3]	[3,1]	-1	hSpCas9	positive selection	4285259
55951397	55951420	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	-0.07159896578421264	[2]	[2,1]	-1	hSpCas9	positive selection	4349516
55993501	55993524	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.18364038584706371	[3]	[2,2]	3	hSpCas9	positive selection	4349517
55951383	55951406	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.47323600344231637	[1]	[0,2]	8	hSpCas9	positive selection	4349518
55850584	55850606	15	-	27760321	OCIAML3	viability	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	0.068951353752632	[401,305]	[344,213]	0	hSpCas9	negative selection	4421825
55860429	55860451	15	+	27760321	OCIAML3	viability	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	1.2260401983515925	[135,93]	[134,302]	9	hSpCas9	negative selection	4421826
55860493	55860515	15	+	27760321	OCIAML3	viability	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	-0.15675614701092364	[452,398]	[207,415]	-2	hSpCas9	negative selection	4421827
55860526	55860548	15	-	27760321	OCIAML3	viability	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	0.3419444712340548	[617,494]	[445,681]	4	hSpCas9	negative selection	4421828
55860712	55860734	15	-	27760321	OCIAML3	viability	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	0.48800072002322836	[332,235]	[240,396]	6	hSpCas9	negative selection	4421829
55850584	55850606	15	-	27760321	OCIAML2	viability	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	-0.01698290538833397	[401,305]	[288,269]	0	hSpCas9	negative selection	4505288
55860429	55860451	15	+	27760321	OCIAML2	viability	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	0.15820396385446744	[135,93]	[77,134]	2	hSpCas9	negative selection	4505289
55860493	55860515	15	+	27760321	OCIAML2	viability	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	-0.04359925056711406	[452,398]	[249,443]	0	hSpCas9	negative selection	4505290
55860526	55860548	15	-	27760321	OCIAML2	viability	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	0.581042737298074	[617,494]	[609,747]	7	hSpCas9	negative selection	4505291
55860712	55860734	15	-	27760321	OCIAML2	viability	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	0.3381765004721676	[332,235]	[270,309]	4	hSpCas9	negative selection	4505292
55850584	55850606	15	-	27760321	MV411	viability	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	-0.750588720884495	[401,305]	[84,216]	-5	hSpCas9	negative selection	4588751
55860429	55860451	15	+	27760321	MV411	viability	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	0.20069202599551472	[135,93]	[78,96]	1	hSpCas9	negative selection	4588752
55860493	55860515	15	+	27760321	MV411	viability	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	-0.6777444790142132	[452,398]	[176,172]	-5	hSpCas9	negative selection	4588753
55860526	55860548	15	-	27760321	MV411	viability	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	0.596564484974635	[617,494]	[655,395]	4	hSpCas9	negative selection	4588754
55860712	55860734	15	-	27760321	MV411	viability	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	1.5343902619654175	[332,235]	[778,175]	9	hSpCas9	negative selection	4588755
55850584	55850606	15	-	27760321	HL60	viability	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	-0.023062839598272822	[401,305]	[260,304]	0	hSpCas9	negative selection	4672214
55860429	55860451	15	+	27760321	HL60	viability	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	-0.3697905270645572	[135,93]	[99,41]	-4	hSpCas9	negative selection	4672215
55860493	55860515	15	+	27760321	HL60	viability	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	0.13502104659433936	[452,398]	[377,384]	1	hSpCas9	negative selection	4672216
55860526	55860548	15	-	27760321	HL60	viability	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	0.7637747359284265	[617,494]	[647,893]	8	hSpCas9	negative selection	4672217
55860712	55860734	15	-	27760321	HL60	viability	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	0.010903605142005168	[332,235]	[269,190]	0	hSpCas9	negative selection	4672218
55850584	55850606	15	-	27760321	HT1080	viability	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	0.8564967313644531	[305,238]	[218,171]	4	hSpCas9	negative selection	4755677
55860429	55860451	15	+	27760321	HT1080	viability	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	1.1523101416395458	[93,73]	[19,133]	6	hSpCas9	negative selection	4755678
55860493	55860515	15	+	27760321	HT1080	viability	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	0.39066525630509624	[398,311]	[157,215]	2	hSpCas9	negative selection	4755679
55860526	55860548	15	-	27760321	HT1080	viability	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	1.3897183229082462	[494,385]	[644,256]	7	hSpCas9	negative selection	4755680
55860712	55860734	15	-	27760321	HT1080	viability	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	1.8217745266284087	[235,183]	[310,278]	8	hSpCas9	negative selection	4755681
55850584	55850606	15	-	27760321	HT29	viability after 7 days	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	0.6469983340917638	[305,238]	[649,536,474]	8	hSpCas9	negative selection	4839140
55860429	55860451	15	+	27760321	HT29	viability after 7 days	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	0.19584347792058687	[93,73]	[202,73,105]	3	hSpCas9	negative selection	4839141
55860493	55860515	15	+	27760321	HT29	viability after 7 days	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	0.23022355902650343	[398,311]	[733,617,291]	3	hSpCas9	negative selection	4839142
55860526	55860548	15	-	27760321	HT29	viability after 7 days	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	0.2996266143665275	[494,385]	[647,669,762]	4	hSpCas9	negative selection	4839143
55860712	55860734	15	-	27760321	HT29	viability after 7 days	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	0.24808282928815895	[235,183]	[242,469,239]	4	hSpCas9	negative selection	4839144
55850584	55850606	15	-	27760321	HT29	viability after 25 days	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	0.7222203667812244	[305,238]	[467,530,547]	7	hSpCas9	negative selection	4922603
55860429	55860451	15	+	27760321	HT29	viability after 25 days	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	0.5108279644420854	[93,73]	[65,175,176]	5	hSpCas9	negative selection	4922604
55860493	55860515	15	+	27760321	HT29	viability after 25 days	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	0.3571647610174041	[398,311]	[552,506,495]	4	hSpCas9	negative selection	4922605
55860526	55860548	15	-	27760321	HT29	viability after 25 days	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	0.8814810819992484	[494,385]	[1129,623,1023]	8	hSpCas9	negative selection	4922606
55860712	55860734	15	-	27760321	HT29	viability after 25 days	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	0.2342202362846746	[235,183]	[323,226,293]	2	hSpCas9	negative selection	4922607
55850584	55850606	15	-	27760321	HT29	viability after 22 days	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	0.7861130452276694	[305,238]	[579,584,462]	8	hSpCas9	negative selection	5006066
55860429	55860451	15	+	27760321	HT29	viability after 22 days	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	0.7922727335210715	[93,73]	[65,329,110]	8	hSpCas9	negative selection	5006067
55860493	55860515	15	+	27760321	HT29	viability after 22 days	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	0.5085714084387917	[398,311]	[694,493,561]	5	hSpCas9	negative selection	5006068
55860526	55860548	15	-	27760321	HT29	viability after 22 days	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	0.8442402683235984	[494,385]	[1033,615,1090]	8	hSpCas9	negative selection	5006069
55860712	55860734	15	-	27760321	HT29	viability after 22 days	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	0.8376106630626894	[235,183]	[623,375,294]	8	hSpCas9	negative selection	5006070
55850584	55850606	15	-	27760321	HT29	viability after 19 days	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	0.6587201812995744	[305,238]	[654,404,434]	6	hSpCas9	negative selection	5089529
55860429	55860451	15	+	27760321	HT29	viability after 19 days	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	0.8042105608595411	[93,73]	[91,329,76]	8	hSpCas9	negative selection	5089530
55860493	55860515	15	+	27760321	HT29	viability after 19 days	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	-0.7897393106524057	[398,311]	[402,190,132]	-6	hSpCas9	negative selection	5089531
55860526	55860548	15	-	27760321	HT29	viability after 19 days	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	1.242156577855292	[494,385]	[973,1160,1407]	9	hSpCas9	negative selection	5089532
55860712	55860734	15	-	27760321	HT29	viability after 19 days	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	1.049898512432922	[235,183]	[398,449,626]	9	hSpCas9	negative selection	5089533
55850584	55850606	15	-	27760321	HT29	viability after 16 days	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	0.6550937108182815	[305,238]	[684,273,505]	7	hSpCas9	negative selection	5172992
55860429	55860451	15	+	27760321	HT29	viability after 16 days	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	0.9332826409004136	[93,73]	[190,245,100]	9	hSpCas9	negative selection	5172993
55860493	55860515	15	+	27760321	HT29	viability after 16 days	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	0.16725466619488363	[398,311]	[604,251,502]	1	hSpCas9	negative selection	5172994
55860526	55860548	15	-	27760321	HT29	viability after 16 days	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	0.4774255138164034	[494,385]	[627,637,787]	5	hSpCas9	negative selection	5172995
55860712	55860734	15	-	27760321	HT29	viability after 16 days	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	0.46740713986599686	[235,183]	[480,254,254]	5	hSpCas9	negative selection	5172996
55850584	55850606	15	-	27760321	HT29	viability after 13 days	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	0.9330256775259504	[305,238]	[682,446,675]	9	hSpCas9	negative selection	5256455
55860429	55860451	15	+	27760321	HT29	viability after 13 days	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	0.580853543353044	[93,73]	[131,167,137]	7	hSpCas9	negative selection	5256456
55860493	55860515	15	+	27760321	HT29	viability after 13 days	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	0.2423595482443708	[398,311]	[490,626,353]	3	hSpCas9	negative selection	5256457
55860526	55860548	15	-	27760321	HT29	viability after 13 days	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	0.7718820552752815	[494,385]	[829,871,912]	8	hSpCas9	negative selection	5256458
55860712	55860734	15	-	27760321	HT29	viability after 13 days	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	0.022023896354114947	[235,183]	[259,285,198]	0	hSpCas9	negative selection	5256459
55850584	55850606	15	-	27760321	HT29	viability after 10 days	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	0.7045101305104199	[305,238]	[738,505,419]	8	hSpCas9	negative selection	5339918
55860429	55860451	15	+	27760321	HT29	viability after 10 days	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	1.3664376668765317	[93,73]	[126,662,37]	9	hSpCas9	negative selection	5339919
55860493	55860515	15	+	27760321	HT29	viability after 10 days	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	-0.0006291827332590601	[398,311]	[503,414,411]	0	hSpCas9	negative selection	5339920
55860526	55860548	15	-	27760321	HT29	viability after 10 days	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	0.5112642576048072	[494,385]	[743,852,756]	7	hSpCas9	negative selection	5339921
55860712	55860734	15	-	27760321	HT29	viability after 10 days	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	-0.11539191599929488	[235,183]	[295,176,250]	-1	hSpCas9	negative selection	5339922
55850584	55850606	15	-	27760321	MOLM13	viability	AGTCCGGCATGCACCAAATGGG	NEDD4	ENSG00000069869	0.2880943040690411	[401,305]	[255,229]	2	hSpCas9	negative selection	5423381
55860429	55860451	15	+	27760321	MOLM13	viability	ACGGCTGAATTTCCAAAAATGG	NEDD4	ENSG00000069869	0.17985649813090898	[135,93]	[16,119]	1	hSpCas9	negative selection	5423382
55860493	55860515	15	+	27760321	MOLM13	viability	CCAAGTTACTTGACGGTGGAGG	NEDD4	ENSG00000069869	0.82442007268056	[452,398]	[440,410]	6	hSpCas9	negative selection	5423383
55860526	55860548	15	-	27760321	MOLM13	viability	GCCACCATGTATAGCAACCAGG	NEDD4	ENSG00000069869	0.31169967601126036	[617,494]	[589,214]	2	hSpCas9	negative selection	5423384
55860712	55860734	15	-	27760321	MOLM13	viability	ACAACGTGCATTTACCACCAGG	NEDD4	ENSG00000069869	-0.8214816373368954	[332,235]	[37,133]	-5	hSpCas9	negative selection	5423385
55993150	55993173	15	+	27661255	K562	viability	GAGCTCCGCACACCCGGCGGGGG	NEDD4	ENSG00000069869	0.05422911140144393	[41,94]	[75,38]	1	dCas9-KRAB	negative selection	5496143
55993247	55993270	15	+	27661255	K562	viability	GAAACTGACAAGTAAGGCGGCGG	NEDD4	ENSG00000069869	0.2884343450576943	[399,424]	[462,349]	8	dCas9-KRAB	negative selection	5496144
55993145	55993168	15	-	27661255	K562	viability	GCCGGGTGTGCGGAGCTCCCAGG	NEDD4	ENSG00000069869	-1.2105145049837585	[284,376]	[90,132]	-8	dCas9-KRAB	negative selection	5496145
55993419	55993442	15	-	27661255	K562	viability	GCGGCGGCGGCCACGACCGGAGG	NEDD4	ENSG00000069869	0.22231955023618805	[651,730]	[702,591]	7	dCas9-KRAB	negative selection	5496146
55993422	55993445	15	-	27661255	K562	viability	GTAGCGGCGGCGGCCACGACCGG	NEDD4	ENSG00000069869	0.13999863388443842	[799,751]	[787,594]	5	dCas9-KRAB	negative selection	5496147
55993540	55993563	15	-	27260156	BXPC3	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.18335846250771148	[930]	[990,1182,1002,1261]	4	hSpCas9	negative selection	5557717
55873953	55873976	15	+	27260156	BXPC3	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.6470362421685292	[235]	[328,338,466,422]	9	hSpCas9	negative selection	5557718
55873957	55873980	15	-	27260156	BXPC3	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.14011194494047757	[578]	[647,636,695,689]	3	hSpCas9	negative selection	5557719
55951397	55951420	15	-	27260156	BXPC3	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.46835479174336697	[395]	[534,569,468,735]	8	hSpCas9	negative selection	5621976
55993501	55993524	15	+	27260156	BXPC3	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.1752486049108789	[494]	[713,514,598,482]	4	hSpCas9	negative selection	5621977
55951383	55951406	15	+	27260156	BXPC3	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.4900153960531731	[175]	[179,312,226,324]	9	hSpCas9	negative selection	5621978
55993540	55993563	15	-	27260156	A673	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.1016248845284774	[930]	[1218,1124,1140,1321]	2	hSpCas9	negative selection	5678968
55873953	55873976	15	+	27260156	A673	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.4686207900944632	[235]	[432,312,422,405]	9	hSpCas9	negative selection	5678969
55873957	55873980	15	-	27260156	A673	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.3026116831723281	[578]	[890,753,844,949]	7	hSpCas9	negative selection	5678970
55951397	55951420	15	-	27260156	A673	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.5221374198239375	[395]	[801,721,639,572]	9	hSpCas9	negative selection	5743227
55993501	55993524	15	+	27260156	A673	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.08547138205746223	[494]	[614,630,647,624]	2	hSpCas9	negative selection	5743228
55951383	55951406	15	+	27260156	A673	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.4148200086778564	[175]	[283,286,237,319]	8	hSpCas9	negative selection	5743229
55993540	55993563	15	-	27260156	A375	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	-0.15269335390862537	[930]	[1122,1196,776,857]	-2	hSpCas9	negative selection	5800219
55873953	55873976	15	+	27260156	A375	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	-0.060074316568097474	[235]	[284,267,209,290]	-1	hSpCas9	negative selection	5800220
55873957	55873980	15	-	27260156	A375	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.3762418681885972	[578]	[868,824,1221,615]	5	hSpCas9	negative selection	5800221
55951397	55951420	15	-	27260156	A375	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.5866190560044695	[395]	[671,768,725,626]	8	hSpCas9	negative selection	5864478
55993501	55993524	15	+	27260156	A375	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.04336868187605821	[494]	[621,609,555,471]	0	hSpCas9	negative selection	5864479
55951383	55951406	15	+	27260156	A375	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.48967220545608003	[175]	[176,356,402,231]	7	hSpCas9	negative selection	5864480
55993540	55993563	15	-	27260156	COLO741	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	-0.04980064013534491	[930]	[1183,1074,1185]	-1	hSpCas9	negative selection	5921470
55873953	55873976	15	+	27260156	COLO741	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	-0.1303445197606501	[235]	[199,265,347]	-3	hSpCas9	negative selection	5921471
55873957	55873980	15	-	27260156	COLO741	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.1479294989377865	[578]	[656,942,841]	3	hSpCas9	negative selection	5921472
55951397	55951420	15	-	27260156	COLO741	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.4608952040101021	[395]	[508,891,672]	8	hSpCas9	negative selection	5985729
55993501	55993524	15	+	27260156	COLO741	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.14830130641646133	[494]	[738,672,692]	3	hSpCas9	negative selection	5985730
55951383	55951406	15	+	27260156	COLO741	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.3219179856050427	[175]	[257,360,225]	6	hSpCas9	negative selection	5985731
55993540	55993563	15	-	27260156	CAL120	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.29726002997615997	[930]	[2220,1125,1049]	4	hSpCas9	negative selection	6042721
55873953	55873976	15	+	27260156	CAL120	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.271917278826717	[235]	[356,185,517]	4	hSpCas9	negative selection	6042722
55873957	55873980	15	-	27260156	CAL120	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.315807555026542	[578]	[811,671,1187]	5	hSpCas9	negative selection	6042723
55951397	55951420	15	-	27260156	CAL120	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.4618178123386243	[395]	[1055,717,324]	7	hSpCas9	negative selection	6106980
55993501	55993524	15	+	27260156	CAL120	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.17243542025568026	[494]	[593,657,812]	2	hSpCas9	negative selection	6106981
55951383	55951406	15	+	27260156	CAL120	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.5601040246983086	[175]	[591,201,216]	8	hSpCas9	negative selection	6106982
55993540	55993563	15	-	27260156	CADOES1	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.14090916606334425	[930]	[1054,716,915,1136]	2	hSpCas9	negative selection	6163972
55873953	55873976	15	+	27260156	CADOES1	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.25648619121798855	[235]	[248,248,257,293]	4	hSpCas9	negative selection	6163973
55873957	55873980	15	-	27260156	CADOES1	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.5752459844026465	[578]	[929,1013,552,708]	8	hSpCas9	negative selection	6163974
55951397	55951420	15	-	27260156	CADOES1	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.5925866001294187	[395]	[361,809,483,566]	8	hSpCas9	negative selection	6228231
55993501	55993524	15	+	27260156	CADOES1	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.37874696510626327	[494]	[624,576,599,591]	6	hSpCas9	negative selection	6228232
55951383	55951406	15	+	27260156	CADOES1	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.8398163578327946	[175]	[206,252,291,424]	9	hSpCas9	negative selection	6228233
55993540	55993563	15	-	27260156	EWS502	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.10262015183618567	[930]	[879,1250,1100,1009]	1	hSpCas9	negative selection	6285223
55873953	55873976	15	+	27260156	EWS502	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.5845076286961728	[235]	[240,533,459,265]	8	hSpCas9	negative selection	6285224
55873957	55873980	15	-	27260156	EWS502	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.3153874202990531	[578]	[668,893,601,897]	5	hSpCas9	negative selection	6285225
55951397	55951420	15	-	27260156	EWS502	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.6010519207921585	[395]	[618,562,629,742]	9	hSpCas9	negative selection	6349482
55993501	55993524	15	+	27260156	EWS502	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.11757279448607152	[494]	[417,444,518,564]	-2	hSpCas9	negative selection	6349483
55951383	55951406	15	+	27260156	EWS502	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.5550612482822735	[175]	[282,346,203,253]	8	hSpCas9	negative selection	6349484
55993540	55993563	15	-	27260156	EW8	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	-0.03281344959136334	[930]	[894,694,565,837]	0	hSpCas9	negative selection	6406474
55873953	55873976	15	+	27260156	EW8	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.2831873579053362	[235]	[181,318,221,203]	5	hSpCas9	negative selection	6406475
55873957	55873980	15	-	27260156	EW8	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.38408508423980847	[578]	[596,528,655,655]	7	hSpCas9	negative selection	6406476
55951397	55951420	15	-	27260156	EW8	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.6043537821694068	[395]	[610,695,323,361]	9	hSpCas9	negative selection	6470733
55993501	55993524	15	+	27260156	EW8	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.2550586524113578	[494]	[505,340,727,298]	5	hSpCas9	negative selection	6470734
55951383	55951406	15	+	27260156	EW8	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.577226758131507	[175]	[263,210,166,221]	8	hSpCas9	negative selection	6470735
55993540	55993563	15	-	27260156	CORL105	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.25285865406920893	[930]	[1216,1071,1881,1116]	5	hSpCas9	negative selection	6527725
55873953	55873976	15	+	27260156	CORL105	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.42320103152275756	[235]	[430,226,449,390]	7	hSpCas9	negative selection	6527726
55873957	55873980	15	-	27260156	CORL105	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.18170353834611552	[578]	[731,677,987,711]	3	hSpCas9	negative selection	6527727
55951397	55951420	15	-	27260156	CORL105	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.6205806518955116	[395]	[665,702,817,678]	9	hSpCas9	negative selection	6591984
55993501	55993524	15	+	27260156	CORL105	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.16239884265391366	[494]	[609,414,491,554]	-3	hSpCas9	negative selection	6591985
55951383	55951406	15	+	27260156	CORL105	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.6234032043175785	[175]	[423,230,373,254]	9	hSpCas9	negative selection	6591986
55993540	55993563	15	-	27260156	HS294T	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.5898604482462516	[930]	[555,507,434,690]	7	hSpCas9	negative selection	6648976
55873953	55873976	15	+	27260156	HS294T	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.7866472795350552	[235]	[219,87,141,178]	8	hSpCas9	negative selection	6648977
55873957	55873980	15	-	27260156	HS294T	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.45044549280193313	[578]	[410,224,288,286]	6	hSpCas9	negative selection	6648978
55951397	55951420	15	-	27260156	HS294T	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.3254826426940764	[395]	[191,292,117,153]	4	hSpCas9	negative selection	6713235
55993501	55993524	15	+	27260156	HS294T	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.3320065150962166	[494]	[153,136,119,205]	-5	hSpCas9	negative selection	6713236
55951383	55951406	15	+	27260156	HS294T	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.042046888410807615	[175]	[50,70,83,76]	0	hSpCas9	negative selection	6713237
55993540	55993563	15	-	27260156	HCC44	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	-0.11263079797430797	[930]	[963,965,1242,767]	-2	hSpCas9	negative selection	6770227
55873953	55873976	15	+	27260156	HCC44	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.295860564665528	[235]	[355,117,494,397]	5	hSpCas9	negative selection	6770228
55873957	55873980	15	-	27260156	HCC44	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.039241822461341724	[578]	[1003,434,981,391]	0	hSpCas9	negative selection	6770229
55951397	55951420	15	-	27260156	HCC44	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.58076506430484	[395]	[763,502,844,625]	8	hSpCas9	negative selection	6834486
55993501	55993524	15	+	27260156	HCC44	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.09809614168058416	[494]	[711,623,738,355]	1	hSpCas9	negative selection	6834487
55951383	55951406	15	+	27260156	HCC44	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.26376482370870646	[175]	[285,176,347,176]	4	hSpCas9	negative selection	6834488
55993540	55993563	15	-	27260156	G402	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	-0.19508301157608254	[930]	[1626,928,707,798]	-2	hSpCas9	negative selection	6891478
55873953	55873976	15	+	27260156	G402	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	-0.27439997945051675	[235]	[396,204,270,105]	-3	hSpCas9	negative selection	6891479
55873957	55873980	15	-	27260156	G402	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.4364088188525621	[578]	[960,916,858,1075]	5	hSpCas9	negative selection	6891480
55951397	55951420	15	-	27260156	G402	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.6260022488373009	[395]	[864,850,619,670]	7	hSpCas9	negative selection	6955737
55993501	55993524	15	+	27260156	G402	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.0859425099071925	[494]	[837,682,606,472]	1	hSpCas9	negative selection	6955738
55951383	55951406	15	+	27260156	G402	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.15629166422853547	[175]	[220,228,260,241]	2	hSpCas9	negative selection	6955739
55993540	55993563	15	-	27260156	L33	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.11797316284916903	[930]	[803,443,592,1212]	2	hSpCas9	negative selection	7012729
55873953	55873976	15	+	27260156	L33	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.4625990725744724	[235]	[319,182,208,202]	8	hSpCas9	negative selection	7012730
55873957	55873980	15	-	27260156	L33	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.15386410382948973	[578]	[623,251,422,664]	3	hSpCas9	negative selection	7012731
55951397	55951420	15	-	27260156	L33	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.14981660477541375	[395]	[486,169,265,430]	3	hSpCas9	negative selection	7076988
55993501	55993524	15	+	27260156	L33	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.22047764606605497	[494]	[367,178,334,363]	-5	hSpCas9	negative selection	7076989
55951383	55951406	15	+	27260156	L33	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.33065655057638654	[175]	[186,72,198,204]	7	hSpCas9	negative selection	7076990
55993540	55993563	15	-	27260156	K562	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.02936319828245859	[930]	[802,914,764,881]	0	hSpCas9	negative selection	7133980
55873953	55873976	15	+	27260156	K562	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.3508580170976706	[235]	[369,122,259,309]	4	hSpCas9	negative selection	7133981
55873957	55873980	15	-	27260156	K562	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.5350856114202439	[578]	[556,506,542,1276]	6	hSpCas9	negative selection	7133982
55951397	55951420	15	-	27260156	K562	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.7971762506024205	[395]	[746,643,762,331]	8	hSpCas9	negative selection	7198239
55993501	55993524	15	+	27260156	K562	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.41219983926504095	[494]	[822,513,575,453]	5	hSpCas9	negative selection	7198240
55951383	55951406	15	+	27260156	K562	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.4954251010377637	[175]	[268,251,205,164]	6	hSpCas9	negative selection	7198241
55993540	55993563	15	-	27260156	HT29	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.17163662561080695	[930]	[1399,1524,1013,1191]	3	hSpCas9	negative selection	7255231
55873953	55873976	15	+	27260156	HT29	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.41060025134964695	[235]	[367,350,463,340]	7	hSpCas9	negative selection	7255232
55873957	55873980	15	-	27260156	HT29	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.4579910952823111	[578]	[1089,1057,892,850]	8	hSpCas9	negative selection	7255233
55951397	55951420	15	-	27260156	HT29	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.6453891735052604	[395]	[716,841,804,658]	9	hSpCas9	negative selection	7319490
55993501	55993524	15	+	27260156	HT29	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.11857187618565763	[494]	[708,709,567,632]	2	hSpCas9	negative selection	7319491
55951383	55951406	15	+	27260156	HT29	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.688930429009575	[175]	[383,347,371,283]	9	hSpCas9	negative selection	7319492
55993540	55993563	15	-	27260156	MHHES1	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.06495966033048484	[930]	[1438,1025,1301,719]	1	hSpCas9	negative selection	7376482
55873953	55873976	15	+	27260156	MHHES1	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.2384351528561124	[235]	[364,376,284,247]	4	hSpCas9	negative selection	7376483
55873957	55873980	15	-	27260156	MHHES1	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.3110736217694817	[578]	[928,905,802,642]	5	hSpCas9	negative selection	7376484
55951397	55951420	15	-	27260156	MHHES1	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.553526091557395	[395]	[547,727,946,429]	8	hSpCas9	negative selection	7440741
55993501	55993524	15	+	27260156	MHHES1	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.02784167493776682	[494]	[547,618,665,456]	0	hSpCas9	negative selection	7440742
55951383	55951406	15	+	27260156	MHHES1	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.4274377659859113	[175]	[382,353,220,151]	7	hSpCas9	negative selection	7440743
55993540	55993563	15	-	27260156	MEWO	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.12432358526886456	[930]	[1000,943,912]	2	hSpCas9	negative selection	7497733
55873953	55873976	15	+	27260156	MEWO	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.27783924435923724	[235]	[354,248,215]	6	hSpCas9	negative selection	7497734
55873957	55873980	15	-	27260156	MEWO	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.0364662709157324	[578]	[570,460,637]	0	hSpCas9	negative selection	7497735
55951397	55951420	15	-	27260156	MEWO	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.5097066283307241	[395]	[581,502,507]	9	hSpCas9	negative selection	7561992
55993501	55993524	15	+	27260156	MEWO	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.01715817177128961	[494]	[745,385,296]	0	hSpCas9	negative selection	7561993
55951383	55951406	15	+	27260156	MEWO	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.2900690795816474	[175]	[221,189,195]	6	hSpCas9	negative selection	7561994
55993540	55993563	15	-	27260156	LNCAPCLONEFGC	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.1667523142057622	[930]	[776,906,959,1149]	2	hSpCas9	negative selection	7618984
55873953	55873976	15	+	27260156	LNCAPCLONEFGC	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.2101897267473375	[235]	[284,239,234,226]	3	hSpCas9	negative selection	7618985
55873957	55873980	15	-	27260156	LNCAPCLONEFGC	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.5713818171268755	[578]	[578,726,891,942]	8	hSpCas9	negative selection	7618986
55951397	55951420	15	-	27260156	LNCAPCLONEFGC	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.5551431767660833	[395]	[445,464,677,546]	8	hSpCas9	negative selection	7683243
55993501	55993524	15	+	27260156	LNCAPCLONEFGC	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.08947781274471521	[494]	[247,563,465,407]	-1	hSpCas9	negative selection	7683244
55951383	55951406	15	+	27260156	LNCAPCLONEFGC	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.8036001447053412	[175]	[341,214,386,187]	9	hSpCas9	negative selection	7683245
55993540	55993563	15	-	27260156	PANC0327	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.513841815141577	[930]	[1347,909,1342,1170]	7	hSpCas9	negative selection	7740235
55873953	55873976	15	+	27260156	PANC0327	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.3808074582170915	[235]	[267,327,140,346]	5	hSpCas9	negative selection	7740236
55873957	55873980	15	-	27260156	PANC0327	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.37772067833810774	[578]	[619,484,928,658]	5	hSpCas9	negative selection	7740237
55951397	55951420	15	-	27260156	PANC0327	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	1.1384883060511926	[395]	[1007,452,772,923]	9	hSpCas9	negative selection	7804494
55993501	55993524	15	+	27260156	PANC0327	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.020144532516952106	[494]	[417,425,425,463]	0	hSpCas9	negative selection	7804495
55951383	55951406	15	+	27260156	PANC0327	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.14342952189063962	[175]	[280,85,274,68]	2	hSpCas9	negative selection	7804496
55993540	55993563	15	-	27260156	NCIH2009	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	-0.08248234117339559	[930]	[1411,1371,932]	-1	hSpCas9	negative selection	7861486
55873953	55873976	15	+	27260156	NCIH2009	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.2435556374767116	[235]	[403,452,314]	3	hSpCas9	negative selection	7861487
55873957	55873980	15	-	27260156	NCIH2009	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.2746295501993562	[578]	[1050,1054,840]	4	hSpCas9	negative selection	7861488
55951397	55951420	15	-	27260156	NCIH2009	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.6000766952782404	[395]	[957,679,902]	8	hSpCas9	negative selection	7925745
55993501	55993524	15	+	27260156	NCIH2009	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.1876234709884375	[494]	[773,534,545]	-3	hSpCas9	negative selection	7925746
55951383	55951406	15	+	27260156	NCIH2009	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.25377207717326744	[175]	[356,275,258]	3	hSpCas9	negative selection	7925747
55993540	55993563	15	-	27260156	NCIH1373	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.6499372058696552	[930]	[1751,834,1128,794]	6	hSpCas9	negative selection	7982737
55873953	55873976	15	+	27260156	NCIH1373	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	-0.261088965764787	[235]	[198,130,348,53]	-3	hSpCas9	negative selection	7982738
55873957	55873980	15	-	27260156	NCIH1373	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.7706903232799053	[578]	[1019,769,1353,343]	7	hSpCas9	negative selection	7982739
55951397	55951420	15	-	27260156	NCIH1373	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	1.2052930097867596	[395]	[1232,1251,669,247]	9	hSpCas9	negative selection	8046996
55993501	55993524	15	+	27260156	NCIH1373	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.3875819158079414	[494]	[492,210,359,178]	-4	hSpCas9	negative selection	8046997
55951383	55951406	15	+	27260156	NCIH1373	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.9033729222662114	[175]	[311,553,261,82]	8	hSpCas9	negative selection	8046998
55993540	55993563	15	-	27260156	PATU8902	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.3348188798996442	[930]	[1495,1580,1524,1999]	3	hSpCas9	negative selection	8103988
55873953	55873976	15	+	27260156	PATU8902	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.25835778425818	[235]	[243,247,665,334]	2	hSpCas9	negative selection	8103989
55873957	55873980	15	-	27260156	PATU8902	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.6831472554041069	[578]	[1472,1174,517,2324]	7	hSpCas9	negative selection	8103990
55951397	55951420	15	-	27260156	PATU8902	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	1.2481550696173247	[395]	[1746,1183,729,1767]	9	hSpCas9	negative selection	8168247
55993501	55993524	15	+	27260156	PATU8902	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.46936659821447196	[494]	[780,1349,457,1407]	5	hSpCas9	negative selection	8168248
55951383	55951406	15	+	27260156	PATU8902	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.25088853879035655	[175]	[542,256,218,142]	2	hSpCas9	negative selection	8168249
55993540	55993563	15	-	27260156	PANC1	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.3347142911120943	[930]	[981,1081,1282,733]	5	hSpCas9	negative selection	8225239
55873953	55873976	15	+	27260156	PANC1	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.4319076502682119	[235]	[338,274,249,230]	7	hSpCas9	negative selection	8225240
55873957	55873980	15	-	27260156	PANC1	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.3198554851740627	[578]	[653,788,547,529]	5	hSpCas9	negative selection	8225241
55951397	55951420	15	-	27260156	PANC1	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.6723702055423108	[395]	[402,794,568,460]	9	hSpCas9	negative selection	8289498
55993501	55993524	15	+	27260156	PANC1	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.23222264050275454	[494]	[391,886,386,417]	3	hSpCas9	negative selection	8289499
55951383	55951406	15	+	27260156	PANC1	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	1.042377288847403	[175]	[272,387,227,358]	9	hSpCas9	negative selection	8289500
55993540	55993563	15	-	27260156	PANC0813	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.12904390602083804	[930]	[1297,1128,1081,1276]	2	hSpCas9	negative selection	8346490
55873953	55873976	15	+	27260156	PANC0813	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.5743001962935235	[235]	[509,342,559,255]	8	hSpCas9	negative selection	8346491
55873957	55873980	15	-	27260156	PANC0813	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.13106749255826378	[578]	[721,774,754,724]	2	hSpCas9	negative selection	8346492
55951397	55951420	15	-	27260156	PANC0813	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.3949689177580883	[395]	[660,500,856,441]	6	hSpCas9	negative selection	8410749
55993501	55993524	15	+	27260156	PANC0813	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.3845838518673996	[494]	[591,289,302,599]	-5	hSpCas9	negative selection	8410750
55951383	55951406	15	+	27260156	PANC0813	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.0547446506060314	[175]	[239,117,282,219]	0	hSpCas9	negative selection	8410751
55993540	55993563	15	-	27260156	RDES	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.17358237403270882	[930]	[1031,1284,1141,1387]	3	hSpCas9	negative selection	8467741
55873953	55873976	15	+	27260156	RDES	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.3303152853651449	[235]	[311,315,311,435]	5	hSpCas9	negative selection	8467742
55873957	55873980	15	-	27260156	RDES	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.36296566448916723	[578]	[646,759,966,1126]	6	hSpCas9	negative selection	8467743
55951397	55951420	15	-	27260156	RDES	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.5344678302642264	[395]	[460,654,809,757]	8	hSpCas9	negative selection	8532000
55993501	55993524	15	+	27260156	RDES	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.08148002046698936	[494]	[418,634,597,807]	1	hSpCas9	negative selection	8532001
55951383	55951406	15	+	27260156	RDES	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.8103513813881887	[175]	[323,255,423,435]	9	hSpCas9	negative selection	8532002
55993540	55993563	15	-	27260156	PC3	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.08522967496594502	[930]	[682,981,1378,1077]	2	hSpCas9	negative selection	8588992
55873953	55873976	15	+	27260156	PC3	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	-0.02414507053360504	[235]	[190,151,453,207]	0	hSpCas9	negative selection	8588993
55873957	55873980	15	-	27260156	PC3	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.2618601534539454	[578]	[447,628,1116,784]	6	hSpCas9	negative selection	8588994
55951397	55951420	15	-	27260156	PC3	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.2451841972823425	[395]	[303,455,796,467]	5	hSpCas9	negative selection	8653251
55993501	55993524	15	+	27260156	PC3	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.11644518245138208	[494]	[212,525,927,402]	-3	hSpCas9	negative selection	8653252
55951383	55951406	15	+	27260156	PC3	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.4797543811730881	[175]	[192,255,246,276]	8	hSpCas9	negative selection	8653253
55993540	55993563	15	-	27260156	PATU8988T	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.15373199283469152	[930]	[1321,907,683,1091]	2	hSpCas9	negative selection	8710243
55873953	55873976	15	+	27260156	PATU8988T	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.22548625488927343	[235]	[230,178,327,323]	4	hSpCas9	negative selection	8710244
55873957	55873980	15	-	27260156	PATU8988T	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.29220359405850915	[578]	[654,910,373,837]	5	hSpCas9	negative selection	8710245
55951397	55951420	15	-	27260156	PATU8988T	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.4464199678725364	[395]	[736,419,426,490]	7	hSpCas9	negative selection	8774502
55993501	55993524	15	+	27260156	PATU8988T	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.0675554914928018	[494]	[463,439,414,509]	-1	hSpCas9	negative selection	8774503
55951383	55951406	15	+	27260156	PATU8988T	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.3645422868517121	[175]	[65,180,419,200]	6	hSpCas9	negative selection	8774504
55993540	55993563	15	-	27260156	T47D	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.21551755632806435	[930]	[1293,978,1349,1442]	4	hSpCas9	negative selection	8831494
55873953	55873976	15	+	27260156	T47D	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.16179712891751674	[235]	[287,317,295,327]	3	hSpCas9	negative selection	8831495
55873957	55873980	15	-	27260156	T47D	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.4902168867508474	[578]	[925,913,973,978]	8	hSpCas9	negative selection	8831496
55951397	55951420	15	-	27260156	T47D	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.46896594402368164	[395]	[664,695,660,522]	8	hSpCas9	negative selection	8895753
55993501	55993524	15	+	27260156	T47D	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.04504939564226876	[494]	[689,514,609,570]	0	hSpCas9	negative selection	8895754
55951383	55951406	15	+	27260156	T47D	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.4009804601491702	[175]	[286,219,343,233]	8	hSpCas9	negative selection	8895755
55993540	55993563	15	-	27260156	SU8686	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.4506514960582567	[930]	[1149,1186,1263,1495]	7	hSpCas9	negative selection	8952745
55873953	55873976	15	+	27260156	SU8686	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.15776204563878926	[235]	[199,232,252,386]	2	hSpCas9	negative selection	8952746
55873957	55873980	15	-	27260156	SU8686	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.33639576013822325	[578]	[580,683,795,881]	6	hSpCas9	negative selection	8952747
55951397	55951420	15	-	27260156	SU8686	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.5560583475851619	[395]	[516,636,475,688]	8	hSpCas9	negative selection	9017004
55993501	55993524	15	+	27260156	SU8686	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.18425038747732397	[494]	[316,483,447,491]	-3	hSpCas9	negative selection	9017005
55951383	55951406	15	+	27260156	SU8686	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.5484985785096049	[175]	[194,270,291,268]	8	hSpCas9	negative selection	9017006
55993540	55993563	15	-	27260156	SKES1	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.066670403526773	[930]	[1111,1186,922,732]	1	hSpCas9	negative selection	9073996
55873953	55873976	15	+	27260156	SKES1	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.2675070980080031	[235]	[303,346,196,292]	5	hSpCas9	negative selection	9073997
55873957	55873980	15	-	27260156	SKES1	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.20073598339181453	[578]	[964,543,456,706]	4	hSpCas9	negative selection	9073998
55951397	55951420	15	-	27260156	SKES1	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.5492814904870348	[395]	[625,628,662,418]	9	hSpCas9	negative selection	9138255
55993501	55993524	15	+	27260156	SKES1	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.03575420420879511	[494]	[615,510,422,403]	-1	hSpCas9	negative selection	9138256
55951383	55951406	15	+	27260156	SKES1	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.5457419990372405	[175]	[246,261,216,291]	9	hSpCas9	negative selection	9138257
55993540	55993563	15	-	27260156	TOV112D	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.07375000485562955	[930]	[1196,826,936,943]	1	hSpCas9	negative selection	9195247
55873953	55873976	15	+	27260156	TOV112D	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	-0.4077757510541642	[235]	[241,198,107,173]	-7	hSpCas9	negative selection	9195248
55873957	55873980	15	-	27260156	TOV112D	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.43271574635018073	[578]	[886,854,660,753]	7	hSpCas9	negative selection	9195249
55951397	55951420	15	-	27260156	TOV112D	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.2688109764077653	[395]	[641,521,391,381]	5	hSpCas9	negative selection	9259506
55993501	55993524	15	+	27260156	TOV112D	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.007451036050986931	[494]	[441,513,601,416]	0	hSpCas9	negative selection	9259507
55951383	55951406	15	+	27260156	TOV112D	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	-0.2956547884650471	[175]	[146,125,147,148]	-5	hSpCas9	negative selection	9259508
55993540	55993563	15	-	27260156	TC71	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	0.1173293249830859	[930]	[960,1040,1018,1328]	3	hSpCas9	negative selection	9316498
55873953	55873976	15	+	27260156	TC71	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.36162489608616843	[235]	[338,250,421,281]	8	hSpCas9	negative selection	9316499
55873957	55873980	15	-	27260156	TC71	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.20342897016295947	[578]	[633,853,590,789]	5	hSpCas9	negative selection	9316500
55951397	55951420	15	-	27260156	TC71	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.5140791886900886	[395]	[784,467,534,636]	9	hSpCas9	negative selection	9380757
55993501	55993524	15	+	27260156	TC71	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	0.1106036747229112	[494]	[470,629,501,700]	3	hSpCas9	negative selection	9380758
55951383	55951406	15	+	27260156	TC71	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.5367229555762586	[175]	[275,259,237,324]	9	hSpCas9	negative selection	9380759
55993540	55993563	15	-	27260156	TC32	viability	TTCGGAAATGGCAACTTGCGCGG	NEDD4	ENSG00000069869	-0.030668390719756244	[930]	[705,646,1106,1069]	0	hSpCas9	negative selection	9437749
55873953	55873976	15	+	27260156	TC32	viability	CCAACCGGTAATGGATAAAGTGG	NEDD4	ENSG00000069869	0.2328291465448722	[235]	[229,224,230,357]	4	hSpCas9	negative selection	9437750
55873957	55873980	15	-	27260156	TC32	viability	TGTTCCACTTTATCCATTACCGG	NEDD4	ENSG00000069869	0.623020792306015	[578]	[692,760,1012,914]	9	hSpCas9	negative selection	9437751
55951397	55951420	15	-	27260156	TC32	viability	TTTAGAGTTTGAATCCAAAGTGG	NEDD4	ENSG00000069869	0.6777444160922528	[395]	[577,411,804,662]	9	hSpCas9	negative selection	9502008
55993501	55993524	15	+	27260156	TC32	viability	GTCCCCGCACCTCGTCCTCCAGG	NEDD4	ENSG00000069869	-0.13909994352973953	[494]	[424,323,445,514]	-2	hSpCas9	negative selection	9502009
55951383	55951406	15	+	27260156	TC32	viability	AATATTTCTTCATTCCACTTTGG	NEDD4	ENSG00000069869	0.7006220301524133	[175]	[229,229,299,326]	9	hSpCas9	negative selection	9502010
55850655	55850678	15	-	27869803	HPAFII	viability after 27 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.995743297097292	[232]	[96,366,NaN]	7	hSpCas9	negative selection	9554082
55852512	55852535	15	-	27869803	HPAFII	viability after 27 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-1.82463291348944	[97]	[19,9,NaN]	-8	hSpCas9	negative selection	9554083
55860489	55860512	15	+	27869803	HPAFII	viability after 27 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.5930655907495275	[336]	[117,116,NaN]	-4	hSpCas9	negative selection	9554084
55860694	55860717	15	+	27869803	HPAFII	viability after 27 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	0.9257827033133096	[72]	[121,31,NaN]	7	hSpCas9	negative selection	9554085
55916191	55916214	15	+	27869803	HPAFII	viability after 27 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.9849886155401095	[158]	[243,99,NaN]	7	hSpCas9	negative selection	9554086
55993537	55993560	15	-	27869803	HPAFII	viability after 27 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-0.0416073207935764	[298]	[179,129,NaN]	0	hSpCas9	negative selection	9554087
55850655	55850678	15	-	27869803	HPAFII	viability after 15 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.8966655420421796	[232]	[361,530,NaN]	8	hSpCas9	negative selection	9636531
55852512	55852535	15	-	27869803	HPAFII	viability after 15 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.75698390832927	[97]	[131,18,NaN]	-7	hSpCas9	negative selection	9636532
55860489	55860512	15	+	27869803	HPAFII	viability after 15 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.10448869984484027	[336]	[474,250,NaN]	-1	hSpCas9	negative selection	9636533
55860694	55860717	15	+	27869803	HPAFII	viability after 15 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	-0.476103276830794	[72]	[85,37,NaN]	-5	hSpCas9	negative selection	9636534
55916191	55916214	15	+	27869803	HPAFII	viability after 15 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.16175882221283905	[158]	[266,143,NaN]	1	hSpCas9	negative selection	9636535
55993537	55993560	15	-	27869803	HPAFII	viability after 15 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-0.2338283124624494	[298]	[411,186,NaN]	-3	hSpCas9	negative selection	9636536
55850655	55850678	15	-	27869803	ASPC1	viability after 36 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.09313539726566712	[648]	[321,326,114]	0	hSpCas9	negative selection	9718980
55852512	55852535	15	-	27869803	ASPC1	viability after 36 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	1.2353578316528238	[215]	[281,148,124]	9	hSpCas9	negative selection	9718981
55860489	55860512	15	+	27869803	ASPC1	viability after 36 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.17081089681835315	[803]	[433,360,193]	1	hSpCas9	negative selection	9718982
55860694	55860717	15	+	27869803	ASPC1	viability after 36 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	1.326644426318225	[79]	[74,26,99]	9	hSpCas9	negative selection	9718983
55916191	55916214	15	+	27869803	ASPC1	viability after 36 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.770297815218494	[362]	[441,135,118]	7	hSpCas9	negative selection	9718984
55993537	55993560	15	-	27869803	ASPC1	viability after 36 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	0.41795063100649044	[963]	[211,579,507]	4	hSpCas9	negative selection	9718985
55850655	55850678	15	-	27869803	PATU8988S	viability after 35 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.22378619366556862	[570]	[293,242,NaN]	2	hSpCas9	negative selection	9801429
55852512	55852535	15	-	27869803	PATU8988S	viability after 35 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	0.09305173283442825	[183]	[97,59,NaN]	1	hSpCas9	negative selection	9801430
55860489	55860512	15	+	27869803	PATU8988S	viability after 35 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.678428145071303	[726]	[162,202,NaN]	-6	hSpCas9	negative selection	9801431
55860694	55860717	15	+	27869803	PATU8988S	viability after 35 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	-1.4793225511734747	[120]	[7,26,NaN]	-8	hSpCas9	negative selection	9801432
55916191	55916214	15	+	27869803	PATU8988S	viability after 35 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.08686605397072494	[381]	[118,207,NaN]	1	hSpCas9	negative selection	9801433
55993537	55993560	15	-	27869803	PATU8988S	viability after 35 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	0.13688184616030702	[746]	[241,419,NaN]	1	hSpCas9	negative selection	9801434
55850655	55850678	15	-	27869803	PATU8988S	viability after 31 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	0.8182093901728633	[570]	[272,564,NaN]	8	hSpCas9	negative selection	9883878
55852512	55852535	15	-	27869803	PATU8988S	viability after 31 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.08100428679913985	[183]	[82,51,NaN]	-1	hSpCas9	negative selection	9883879
55860489	55860512	15	+	27869803	PATU8988S	viability after 31 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.8925168454704866	[726]	[127,191,NaN]	-7	hSpCas9	negative selection	9883880
55860694	55860717	15	+	27869803	PATU8988S	viability after 31 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	-0.7204942995435095	[120]	[34,21,NaN]	-6	hSpCas9	negative selection	9883881
55916191	55916214	15	+	27869803	PATU8988S	viability after 31 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	-0.10243605603730077	[381]	[140,142,NaN]	-1	hSpCas9	negative selection	9883882
55993537	55993560	15	-	27869803	PATU8988S	viability after 31 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	0.16167665651639335	[746]	[253,433,NaN]	2	hSpCas9	negative selection	9883883
55850655	55850678	15	-	27869803	HPAFII	viability after 35 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	1.478719137477562	[232]	[46,645,NaN]	8	hSpCas9	negative selection	9966327
55852512	55852535	15	-	27869803	HPAFII	viability after 35 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.25490492646344376	[97]	[18,66,NaN]	-2	hSpCas9	negative selection	9966328
55860489	55860512	15	+	27869803	HPAFII	viability after 35 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.26087908925698433	[336]	[84,206,NaN]	-2	hSpCas9	negative selection	9966329
55860694	55860717	15	+	27869803	HPAFII	viability after 35 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	0.520614750686146	[72]	[84,16,NaN]	3	hSpCas9	negative selection	9966330
55916191	55916214	15	+	27869803	HPAFII	viability after 35 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.9341024601463421	[158]	[221,76,NaN]	6	hSpCas9	negative selection	9966331
55993537	55993560	15	-	27869803	HPAFII	viability after 35 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-0.2220477392229433	[298]	[149,106,NaN]	-1	hSpCas9	negative selection	9966332
55850655	55850678	15	-	27869803	HPAFII	viability after 31 days	CACCAGTGATTCAGGCCAGCAGG	NEDD4	ENSG00000069869	1.532517539770591	[232]	[138,638,NaN]	9	hSpCas9	negative selection	10048776
55852512	55852535	15	-	27869803	HPAFII	viability after 31 days	ACTTCATCTGGATTACCACCAGG	NEDD4	ENSG00000069869	-0.5336823397650723	[97]	[48,25,NaN]	-4	hSpCas9	negative selection	10048777
55860489	55860512	15	+	27869803	HPAFII	viability after 31 days	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.9241254801473192	[336]	[69,131,NaN]	-5	hSpCas9	negative selection	10048778
55860694	55860717	15	+	27869803	HPAFII	viability after 31 days	TTCCTCGGATATCTGCCGCCTGG	NEDD4	ENSG00000069869	0.08838405886002265	[72]	[55,29,NaN]	0	hSpCas9	negative selection	10048779
55916191	55916214	15	+	27869803	HPAFII	viability after 31 days	CTATTGGAGGTGCTGTCAGAAGG	NEDD4	ENSG00000069869	0.7690935567855923	[158]	[175,125,NaN]	5	hSpCas9	negative selection	10048780
55993537	55993560	15	-	27869803	HPAFII	viability after 31 days	GGAAATGGCAACTTGCGCGGTGG	NEDD4	ENSG00000069869	-0.10628556244364137	[298]	[130,182,NaN]	0	hSpCas9	negative selection	10048781
55860709	55860732	15	-	28162770	P31FUJ	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.22287727936181104	[209]	[287]	2	hSpCas9	negative selection	10199159
55840485	55840508	15	+	28162770	P31FUJ	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	0.8954584704250526	[241]	[528]	8	hSpCas9	negative selection	10199160
55850601	55850624	15	+	28162770	P31FUJ	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-0.3614443558534834	[210]	[192]	-3	hSpCas9	negative selection	10199161
55850530	55850553	15	+	28162770	P31FUJ	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	0.22137368877142327	[99]	[136]	2	hSpCas9	negative selection	10199162
55848544	55848567	15	-	28162770	P31FUJ	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	-0.09927853157698907	[329]	[361]	-1	hSpCas9	negative selection	10199163
55842061	55842084	15	-	28162770	P31FUJ	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	-0.33052202493653315	[396]	[370]	-3	hSpCas9	negative selection	10199164
55860489	55860512	15	+	28162770	P31FUJ	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.2904566962816022	[413]	[594]	3	hSpCas9	negative selection	10199165
55856130	55856153	15	-	28162770	P31FUJ	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.1529814898893509	[273]	[357]	1	hSpCas9	negative selection	10199166
55856123	55856146	15	+	28162770	P31FUJ	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.024912803617305856	[316]	[378]	0	hSpCas9	negative selection	10199167
55852412	55852435	15	+	28162770	P31FUJ	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	0.3666598660018925	[65]	[99]	4	hSpCas9	negative selection	10199168
55860709	55860732	15	-	28162770	TF1	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10368525
55840485	55840508	15	+	28162770	TF1	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10368526
55850601	55850624	15	+	28162770	TF1	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10368527
55850530	55850553	15	+	28162770	TF1	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10368528
55848544	55848567	15	-	28162770	TF1	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10368529
55842061	55842084	15	-	28162770	TF1	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	NaN	[NaN]	[217]	1	hSpCas9	negative selection	10368530
55860489	55860512	15	+	28162770	TF1	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	NaN	[NaN]	[428]	1	hSpCas9	negative selection	10368531
55856130	55856153	15	-	28162770	TF1	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	NaN	[NaN]	[260]	1	hSpCas9	negative selection	10368532
55856123	55856146	15	+	28162770	TF1	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	NaN	[NaN]	[306]	1	hSpCas9	negative selection	10368533
55852412	55852435	15	+	28162770	TF1	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10368534
55860709	55860732	15	-	28162770	SKM1	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.971547424510568	[44]	[155]	8	hSpCas9	negative selection	10537891
55840485	55840508	15	+	28162770	SKM1	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	1.0834526654709942	[66]	[250]	8	hSpCas9	negative selection	10537892
55850601	55850624	15	+	28162770	SKM1	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-0.12156197988091315	[63]	[103]	-1	hSpCas9	negative selection	10537893
55850530	55850553	15	+	28162770	SKM1	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	-0.2914869813232259	[26]	[38]	-2	hSpCas9	negative selection	10537894
55848544	55848567	15	-	28162770	SKM1	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	-0.6652761943345523	[121]	[135]	-5	hSpCas9	negative selection	10537895
55842061	55842084	15	-	28162770	SKM1	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	-0.057218159716037054	[112]	[191]	0	hSpCas9	negative selection	10537896
55860489	55860512	15	+	28162770	SKM1	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.061042155632145434	[121]	[224]	0	hSpCas9	negative selection	10537897
55856130	55856153	15	-	28162770	SKM1	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.8089732004559866	[71]	[222]	7	hSpCas9	negative selection	10537898
55856123	55856146	15	+	28162770	SKM1	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.020118642196275238	[81]	[146]	0	hSpCas9	negative selection	10537899
55852412	55852435	15	+	28162770	SKM1	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	-0.8220016980220057	[6]	[6]	-6	hSpCas9	negative selection	10537900
55860709	55860732	15	-	28162770	SKM1	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.971547424510568	[44]	[155]	8	hSpCas9	negative selection	10707257
55840485	55840508	15	+	28162770	SKM1	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	1.0834526654709942	[66]	[250]	8	hSpCas9	negative selection	10707258
55850601	55850624	15	+	28162770	SKM1	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-0.12156197988091315	[63]	[103]	-1	hSpCas9	negative selection	10707259
55850530	55850553	15	+	28162770	SKM1	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	-0.2914869813232259	[26]	[38]	-2	hSpCas9	negative selection	10707260
55848544	55848567	15	-	28162770	SKM1	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	-0.6652761943345523	[121]	[135]	-5	hSpCas9	negative selection	10707261
55842061	55842084	15	-	28162770	SKM1	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	-0.057218159716037054	[112]	[191]	0	hSpCas9	negative selection	10707262
55860489	55860512	15	+	28162770	SKM1	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.061042155632145434	[121]	[224]	0	hSpCas9	negative selection	10707263
55856130	55856153	15	-	28162770	SKM1	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.8089732004559866	[71]	[222]	7	hSpCas9	negative selection	10707264
55856123	55856146	15	+	28162770	SKM1	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.020118642196275238	[81]	[146]	0	hSpCas9	negative selection	10707265
55852412	55852435	15	+	28162770	SKM1	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	-0.8220016980220057	[6]	[6]	-6	hSpCas9	negative selection	10707266
55860709	55860732	15	-	28162770	PL21	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	-0.7344073240220637	[236]	[61]	-5	hSpCas9	negative selection	10876623
55840485	55840508	15	+	28162770	PL21	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	-0.07587264534268356	[200]	[82]	0	hSpCas9	negative selection	10876624
55850601	55850624	15	+	28162770	PL21	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	0.6865617470049293	[206]	[144]	6	hSpCas9	negative selection	10876625
55850530	55850553	15	+	28162770	PL21	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	-0.8807803808942474	[109]	[25]	-6	hSpCas9	negative selection	10876626
55848544	55848567	15	-	28162770	PL21	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	-0.13499401919730958	[438]	[173]	-1	hSpCas9	negative selection	10876627
55842061	55842084	15	-	28162770	PL21	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.216478351304068	[438]	[221]	2	hSpCas9	negative selection	10876628
55860489	55860512	15	+	28162770	PL21	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.5096589226856019	[396]	[245]	4	hSpCas9	negative selection	10876629
55856130	55856153	15	-	28162770	PL21	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.5150129518427319	[245]	[152]	4	hSpCas9	negative selection	10876630
55856123	55856146	15	+	28162770	PL21	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.7359292732287741	[188]	[136]	6	hSpCas9	negative selection	10876631
55852412	55852435	15	+	28162770	PL21	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	-0.7666935215754802	[42]	[10]	-5	hSpCas9	negative selection	10876632
55860709	55860732	15	-	28162770	P31FUJ	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.22287727936181104	[209]	[287]	2	hSpCas9	negative selection	11045989
55840485	55840508	15	+	28162770	P31FUJ	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	0.8954584704250526	[241]	[528]	8	hSpCas9	negative selection	11045990
55850601	55850624	15	+	28162770	P31FUJ	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-0.3614443558534834	[210]	[192]	-3	hSpCas9	negative selection	11045991
55850530	55850553	15	+	28162770	P31FUJ	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	0.22137368877142327	[99]	[136]	2	hSpCas9	negative selection	11045992
55848544	55848567	15	-	28162770	P31FUJ	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	-0.09927853157698907	[329]	[361]	-1	hSpCas9	negative selection	11045993
55842061	55842084	15	-	28162770	P31FUJ	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	-0.33052202493653315	[396]	[370]	-3	hSpCas9	negative selection	11045994
55860489	55860512	15	+	28162770	P31FUJ	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.2904566962816022	[413]	[594]	3	hSpCas9	negative selection	11045995
55856130	55856153	15	-	28162770	P31FUJ	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.1529814898893509	[273]	[357]	1	hSpCas9	negative selection	11045996
55856123	55856146	15	+	28162770	P31FUJ	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.024912803617305856	[316]	[378]	0	hSpCas9	negative selection	11045997
55852412	55852435	15	+	28162770	P31FUJ	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	0.3666598660018925	[65]	[99]	4	hSpCas9	negative selection	11045998
55860709	55860732	15	-	28162770	OCIAML5	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.2936108843316381	[79]	[176]	2	hSpCas9	negative selection	11215355
55840485	55840508	15	+	28162770	OCIAML5	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	0.016495906085422174	[177]	[324]	0	hSpCas9	negative selection	11215356
55850601	55850624	15	+	28162770	OCIAML5	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	0.1582017645898302	[139]	[281]	1	hSpCas9	negative selection	11215357
55850530	55850553	15	+	28162770	OCIAML5	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	0.9178136457749443	[38]	[132]	7	hSpCas9	negative selection	11215358
55848544	55848567	15	-	28162770	OCIAML5	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	0.5375856099949332	[128]	[337]	5	hSpCas9	negative selection	11215359
55842061	55842084	15	-	28162770	OCIAML5	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.4727440325564868	[199]	[500]	4	hSpCas9	negative selection	11215360
55860489	55860512	15	+	28162770	OCIAML5	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.2604872513491727	[227]	[492]	2	hSpCas9	negative selection	11215361
55856130	55856153	15	-	28162770	OCIAML5	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.32882954839931844	[261]	[593]	2	hSpCas9	negative selection	11215362
55856123	55856146	15	+	28162770	OCIAML5	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	-0.368918883252892	[180]	[252]	-3	hSpCas9	negative selection	11215363
55852412	55852435	15	+	28162770	OCIAML5	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	2.1835573388667244	[9]	[81]	9	hSpCas9	negative selection	11215364
55860709	55860732	15	-	28162770	EOL1	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.14970027609222303	[372]	[217]	1	hSpCas9	negative selection	11384721
55840485	55840508	15	+	28162770	EOL1	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	-0.25232999051354477	[259]	[114]	-2	hSpCas9	negative selection	11384722
55850601	55850624	15	+	28162770	EOL1	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	0.6491045790456607	[396]	[327]	6	hSpCas9	negative selection	11384723
55850530	55850553	15	+	28162770	EOL1	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	-0.0843303797759184	[162]	[80]	0	hSpCas9	negative selection	11384724
55848544	55848567	15	-	28162770	EOL1	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	0.08790115147397648	[708]	[396]	0	hSpCas9	negative selection	11384725
55842061	55842084	15	-	28162770	EOL1	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.4276918562721448	[658]	[466]	4	hSpCas9	negative selection	11384726
55860489	55860512	15	+	28162770	EOL1	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	-0.16291506967980474	[509]	[239]	-1	hSpCas9	negative selection	11384727
55856130	55856153	15	-	28162770	EOL1	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	-0.7630297956335084	[334]	[103]	-5	hSpCas9	negative selection	11384728
55856123	55856146	15	+	28162770	EOL1	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.7188340913807172	[300]	[260]	6	hSpCas9	negative selection	11384729
55852412	55852435	15	+	28162770	EOL1	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	1.1627075087652992	[38]	[45]	8	hSpCas9	negative selection	11384730
55860709	55860732	15	-	28162770	MOLM13	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.7977371397281792	[217]	[273]	6	hSpCas9	negative selection	11554087
55840485	55840508	15	+	28162770	MOLM13	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	-0.12886954664042444	[306]	[202]	-1	hSpCas9	negative selection	11554088
55850601	55850624	15	+	28162770	MOLM13	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-0.037505861858259035	[290]	[204]	0	hSpCas9	negative selection	11554089
55850530	55850553	15	+	28162770	MOLM13	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	0.5800988851306039	[135]	[146]	4	hSpCas9	negative selection	11554090
55848544	55848567	15	-	28162770	MOLM13	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	0.6497939607034908	[572]	[649]	5	hSpCas9	negative selection	11554091
55842061	55842084	15	-	28162770	MOLM13	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.6514189805435725	[515]	[585]	5	hSpCas9	negative selection	11554092
55860489	55860512	15	+	28162770	MOLM13	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.5754178458490239	[503]	[542]	4	hSpCas9	negative selection	11554093
55856130	55856153	15	-	28162770	MOLM13	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	-1.222426119322806	[496]	[153]	-6	hSpCas9	negative selection	11554094
55856123	55856146	15	+	28162770	MOLM13	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.20754908488004814	[320]	[267]	1	hSpCas9	negative selection	11554095
55852412	55852435	15	+	28162770	MOLM13	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	0.8304594609292872	[48]	[62]	6	hSpCas9	negative selection	11554096
55860709	55860732	15	-	28162770	HEL	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	-1.0304508517325346	[235]	[73]	-6	hSpCas9	negative selection	11723453
55840485	55840508	15	+	28162770	HEL	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	-0.6215344704667954	[232]	[96]	-4	hSpCas9	negative selection	11723454
55850601	55850624	15	+	28162770	HEL	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-0.3114574783865181	[247]	[127]	-2	hSpCas9	negative selection	11723455
55850530	55850553	15	+	28162770	HEL	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	1.0235606159412878	[95]	[124]	8	hSpCas9	negative selection	11723456
55848544	55848567	15	-	28162770	HEL	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	-0.20007783544891278	[555]	[309]	-1	hSpCas9	negative selection	11723457
55842061	55842084	15	-	28162770	HEL	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.3699338645744077	[562]	[465]	3	hSpCas9	negative selection	11723458
55860489	55860512	15	+	28162770	HEL	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.21042334128967755	[447]	[331]	1	hSpCas9	negative selection	11723459
55856130	55856153	15	-	28162770	HEL	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	-1.3119802886987766	[344]	[88]	-6	hSpCas9	negative selection	11723460
55856123	55856146	15	+	28162770	HEL	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.6495279976629962	[211]	[212]	5	hSpCas9	negative selection	11723461
55852412	55852435	15	+	28162770	HEL	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	0.5800030766523943	[46]	[44]	5	hSpCas9	negative selection	11723462
55860709	55860732	15	-	28162770	MV411	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.5255932436412322	[173]	[210]	5	hSpCas9	negative selection	11892819
55840485	55840508	15	+	28162770	MV411	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	-0.34613808024308906	[251]	[166]	-3	hSpCas9	negative selection	11892820
55850601	55850624	15	+	28162770	MV411	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-1.473408378020154	[266]	[80]	-7	hSpCas9	negative selection	11892821
55850530	55850553	15	+	28162770	MV411	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	1.6958980515990696	[95]	[261]	9	hSpCas9	negative selection	11892822
55848544	55848567	15	-	28162770	MV411	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	-0.4473130954764926	[347]	[214]	-3	hSpCas9	negative selection	11892823
55842061	55842084	15	-	28162770	MV411	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.4777890433179979	[438]	[514]	4	hSpCas9	negative selection	11892824
55860489	55860512	15	+	28162770	MV411	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.018736876978104	[381]	[325]	0	hSpCas9	negative selection	11892825
55856130	55856153	15	-	28162770	MV411	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.3450483474091976	[199]	[213]	3	hSpCas9	negative selection	11892826
55856123	55856146	15	+	28162770	MV411	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.466272152706034	[231]	[269]	4	hSpCas9	negative selection	11892827
55852412	55852435	15	+	28162770	MV411	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	0.5605954360424059	[32]	[40]	5	hSpCas9	negative selection	11892828
55860709	55860732	15	-	28162770	MONOMAC1	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	0.08589711621194496	[119]	[145]	0	hSpCas9	negative selection	12062185
55840485	55840508	15	+	28162770	MONOMAC1	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	0.17493193032740412	[118]	[153]	1	hSpCas9	negative selection	12062186
55850601	55850624	15	+	28162770	MONOMAC1	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	0.6757279646443386	[153]	[281]	6	hSpCas9	negative selection	12062187
55850530	55850553	15	+	28162770	MONOMAC1	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	-0.07674261334184196	[68]	[74]	0	hSpCas9	negative selection	12062188
55848544	55848567	15	-	28162770	MONOMAC1	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	-0.5794081574180753	[261]	[200]	-5	hSpCas9	negative selection	12062189
55842061	55842084	15	-	28162770	MONOMAC1	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.06097948400761566	[239]	[286]	0	hSpCas9	negative selection	12062190
55860489	55860512	15	+	28162770	MONOMAC1	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.5276504173282158	[235]	[389]	5	hSpCas9	negative selection	12062191
55856130	55856153	15	-	28162770	MONOMAC1	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.7718406354446659	[163]	[320]	7	hSpCas9	negative selection	12062192
55856123	55856146	15	+	28162770	MONOMAC1	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.7253422558179725	[104]	[198]	7	hSpCas9	negative selection	12062193
55852412	55852435	15	+	28162770	MONOMAC1	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	-1.2514846310819303	[26]	[12]	-7	hSpCas9	negative selection	12062194
55860709	55860732	15	-	28162770	OCIAML2	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	-0.156314914464674	[37]	[188]	-1	hSpCas9	negative selection	12231551
55840485	55840508	15	+	28162770	OCIAML2	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	0.94573307150325	[33]	[362]	8	hSpCas9	negative selection	12231552
55850601	55850624	15	+	28162770	OCIAML2	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-0.47062982524216135	[42]	[171]	-4	hSpCas9	negative selection	12231553
55850530	55850553	15	+	28162770	OCIAML2	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	0.01969580134091964	[20]	[117]	0	hSpCas9	negative selection	12231554
55848544	55848567	15	-	28162770	OCIAML2	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	0.02579600087733791	[83]	[473]	0	hSpCas9	negative selection	12231555
55842061	55842084	15	-	28162770	OCIAML2	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	0.086181635164846	[68]	[405]	0	hSpCas9	negative selection	12231556
55860489	55860512	15	+	28162770	OCIAML2	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.3723490065461643	[79]	[573]	3	hSpCas9	negative selection	12231557
55856130	55856153	15	-	28162770	OCIAML2	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.12630531714507104	[39]	[241]	1	hSpCas9	negative selection	12231558
55856123	55856146	15	+	28162770	OCIAML2	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.5293701747578389	[32]	[263]	5	hSpCas9	negative selection	12231559
55852412	55852435	15	+	28162770	OCIAML2	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	0.27187395246547474	[12]	[86]	2	hSpCas9	negative selection	12231560
55860709	55860732	15	-	28162770	OCIAML3	viability	AACGTGCATTTACCACCAGGCGG	NEDD4	ENSG00000069869	-0.38964914181797694	[45]	[105]	-3	hSpCas9	negative selection	12400917
55840485	55840508	15	+	28162770	OCIAML3	viability	GCATCATCTTGTAAAATGGGCGG	NEDD4	ENSG00000069869	-0.28084975506453297	[65]	[163]	-2	hSpCas9	negative selection	12400918
55850601	55850624	15	+	28162770	OCIAML3	viability	GGACTTCCCAGCCTTTAGGAAGG	NEDD4	ENSG00000069869	-0.5080344172143103	[56]	[120]	-4	hSpCas9	negative selection	12400919
55850530	55850553	15	+	28162770	OCIAML3	viability	TATCAAAGTTACCCAGGTGGTGG	NEDD4	ENSG00000069869	-0.4988504072838231	[21]	[46]	-4	hSpCas9	negative selection	12400920
55848544	55848567	15	-	28162770	OCIAML3	viability	GAAGAGAGAACTCACACAGATGG	NEDD4	ENSG00000069869	-0.15065974502194213	[81]	[222]	-1	hSpCas9	negative selection	12400921
55842061	55842084	15	-	28162770	OCIAML3	viability	CAAGAGAGCAGACTTCCTGAAGG	NEDD4	ENSG00000069869	1.2944457070276791	[83]	[621]	9	hSpCas9	negative selection	12400922
55860489	55860512	15	+	28162770	OCIAML3	viability	ACATCCAAGTTACTTGACGGTGG	NEDD4	ENSG00000069869	0.4517960492889619	[123]	[511]	4	hSpCas9	negative selection	12400923
55856130	55856153	15	-	28162770	OCIAML3	viability	GGAACAACCTACACTTCCTGTGG	NEDD4	ENSG00000069869	0.4251859249091477	[55]	[226]	4	hSpCas9	negative selection	12400924
55856123	55856146	15	+	28162770	OCIAML3	viability	AAACTCACCACAGGAAGTGTAGG	NEDD4	ENSG00000069869	0.9198717623355105	[51]	[296]	7	hSpCas9	negative selection	12400925
55852412	55852435	15	+	28162770	OCIAML3	viability	ATTACAGGATACCTGTACAGTGG	NEDD4	ENSG00000069869	-0.47853042290422687	[11]	[25]	-4	hSpCas9	negative selection	12400926