Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4763
• Symbol:Nf1
• Description:neurofibromin 1

DataSource: http://genomecrispr.dkfz.de/#!/results/Nf1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
31163310	31163333	17	-	26472758	Jiyoye	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	5.833440136207971	[1]	[85]	9	hSpCas9	negative selection	108146
31156021	31156044	17	+	26472758	Jiyoye	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.9497026159066331	[45]	[66]	6	hSpCas9	negative selection	108147
31219014	31219037	17	+	26472758	Jiyoye	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	-0.9464615731088268	[68]	[26]	-6	hSpCas9	negative selection	108148
31219094	31219117	17	+	26472758	Jiyoye	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	5.407175381505873	[0]	[31]	9	hSpCas9	negative selection	108149
31095325	31095348	17	-	26472758	Jiyoye	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.35638442267204595	[218]	[128]	-3	hSpCas9	negative selection	108150
31182620	31182643	17	+	26472758	Jiyoye	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.6354443691789906	[69]	[81]	4	hSpCas9	negative selection	108151
31200446	31200469	17	+	26472758	Jiyoye	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	0.7214499038498006	[188]	[234]	5	hSpCas9	negative selection	108152
31219000	31219023	17	+	26472758	Jiyoye	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	1.0701403942283028	[35]	[56]	7	hSpCas9	negative selection	108153
31206344	31206367	17	+	26472758	Jiyoye	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	-0.7658893274670062	[114]	[50]	-5	hSpCas9	negative selection	108154
31095348	31095371	17	+	26472758	Jiyoye	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	-1.2129765476775827	[165]	[53]	-7	hSpCas9	negative selection	108155
31163310	31163333	17	-	26472758	KBM7	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	-0.49972790782289467	[179,60]	[61,16]	-4	hSpCas9	negative selection	299264
31156021	31156044	17	+	26472758	KBM7	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.24705420509422804	[273,358]	[198,63]	-2	hSpCas9	negative selection	299265
31219014	31219037	17	+	26472758	KBM7	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	0.4212552304235413	[221,52]	[89,73]	4	hSpCas9	negative selection	299266
31219094	31219117	17	+	26472758	KBM7	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	0.7167202765643177	[20,69]	[69,7]	7	hSpCas9	negative selection	299267
31095325	31095348	17	-	26472758	KBM7	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.06080630848271473	[952,643]	[512,271]	0	hSpCas9	negative selection	299268
31182620	31182643	17	+	26472758	KBM7	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.2218466049561023	[321,186]	[131,71]	-2	hSpCas9	negative selection	299269
31200446	31200469	17	+	26472758	KBM7	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	0.49280917629334897	[1027,833]	[849,399]	5	hSpCas9	negative selection	299270
31219000	31219023	17	+	26472758	KBM7	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	0.21965866634315134	[217,233]	[175,78]	2	hSpCas9	negative selection	299271
31206344	31206367	17	+	26472758	KBM7	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	-0.11598121024870522	[337,340]	[155,140]	-1	hSpCas9	negative selection	299272
31095348	31095371	17	+	26472758	KBM7	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	0.4559890416234177	[481,257]	[252,213]	5	hSpCas9	negative selection	299273
31163310	31163333	17	-	26472758	Raji	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	0.07289515898830878	[126]	[30]	0	hSpCas9	negative selection	490382
31156021	31156044	17	+	26472758	Raji	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.9860772391514658	[123]	[56]	8	hSpCas9	negative selection	490383
31219014	31219037	17	+	26472758	Raji	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	1.8343650409671834	[28]	[23]	9	hSpCas9	negative selection	490384
31219094	31219117	17	+	26472758	Raji	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	0.30002861331599506	[13]	[3]	3	hSpCas9	negative selection	490385
31095325	31095348	17	-	26472758	Raji	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.17381089711257547	[381]	[99]	1	hSpCas9	negative selection	490386
31182620	31182643	17	+	26472758	Raji	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.441120932550595	[72]	[45]	9	hSpCas9	negative selection	490387
31200446	31200469	17	+	26472758	Raji	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	0.5419172102782405	[440]	[148]	5	hSpCas9	negative selection	490388
31219000	31219023	17	+	26472758	Raji	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	1.1813841168173764	[94]	[49]	9	hSpCas9	negative selection	490389
31206344	31206367	17	+	26472758	Raji	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	0.3086417436207033	[166]	[47]	3	hSpCas9	negative selection	490390
31095348	31095371	17	+	26472758	Raji	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	0.8616271209716411	[165]	[69]	7	hSpCas9	negative selection	490391
31163310	31163333	17	-	26472758	K562	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	1.3873766815084898	[95]	[211]	9	hSpCas9	negative selection	681500
31156021	31156044	17	+	26472758	K562	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.8259706002249511	[251]	[119]	-5	hSpCas9	negative selection	681501
31219014	31219037	17	+	26472758	K562	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	-0.497783514865906	[91]	[54]	-3	hSpCas9	negative selection	681502
31219094	31219117	17	+	26472758	K562	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	-0.2449661130724783	[72]	[51]	-2	hSpCas9	negative selection	681503
31095325	31095348	17	-	26472758	K562	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.00028452717593230314	[545]	[460]	0	hSpCas9	negative selection	681504
31182620	31182643	17	+	26472758	K562	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.2749554314271325	[257]	[179]	-2	hSpCas9	negative selection	681505
31200446	31200469	17	+	26472758	K562	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	0.8103039911924561	[811]	[1201]	6	hSpCas9	negative selection	681506
31219000	31219023	17	+	26472758	K562	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	0.1549836440845026	[182]	[171]	1	hSpCas9	negative selection	681507
31206344	31206367	17	+	26472758	K562	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	0.3572601971821126	[294]	[318]	3	hSpCas9	negative selection	681508
31095348	31095371	17	+	26472758	K562	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	0.6629879179155439	[305]	[408]	5	hSpCas9	negative selection	681509
31095325	31095348	17	-	26627737	DLD1	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-1.486471038817113	[571]	[36,52,95]	-8	hSpCas9	negative selection	796897
31156021	31156044	17	+	26627737	DLD1	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-2.7434916471672053	[1013]	[57,73,15]	-9	hSpCas9	negative selection	796898
31163265	31163288	17	-	26627737	DLD1	viability	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	-1.1565310421681176	[790]	[97,133,102]	-7	hSpCas9	negative selection	796899
31182620	31182643	17	+	26627737	DLD1	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-1.3108530102179992	[776]	[57,147,90]	-8	hSpCas9	negative selection	796900
31206350	31206373	17	+	26627737	DLD1	viability	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	-0.03904614658897043	[1098]	[236,199,529]	0	hSpCas9	negative selection	796901
31232842	31232865	17	+	26627737	DLD1	viability	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	-0.2944002904338252	[2036]	[599,481,479]	-3	hSpCas9	negative selection	796902
31095325	31095348	17	-	26627737	GBM cells	viability after 5 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-1.0225527225676252	[285]	[101,48]	-9	hSpCas9	negative selection	879212
31156021	31156044	17	+	26627737	GBM cells	viability after 5 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.5410580362541191	[370]	[303,274]	7	hSpCas9	negative selection	879213
31163265	31163288	17	-	26627737	GBM cells	viability after 5 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.8311473186086673	[315]	[318,283]	9	hSpCas9	negative selection	879214
31182620	31182643	17	+	26627737	GBM cells	viability after 5 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.16008931248229852	[548]	[241,284]	-2	hSpCas9	negative selection	879215
31206350	31206373	17	+	26627737	GBM cells	viability after 5 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	0.057373689834543606	[378]	[227,194]	0	hSpCas9	negative selection	879216
31232842	31232865	17	+	26627737	GBM cells	viability after 5 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.12084924092260696	[901]	[550,500]	2	hSpCas9	negative selection	879217
31095325	31095348	17	-	26627737	GBM cells	viability after 13 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-1.3524319502706055	[285]	[89,36]	-8	hSpCas9	negative selection	961527
31156021	31156044	17	+	26627737	GBM cells	viability after 13 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.6411444113654701	[370]	[394,247]	7	hSpCas9	negative selection	961528
31163265	31163288	17	-	26627737	GBM cells	viability after 13 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.4750999593811284	[315]	[266,214]	6	hSpCas9	negative selection	961529
31182620	31182643	17	+	26627737	GBM cells	viability after 13 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.07191567227334406	[548]	[305,264]	-1	hSpCas9	negative selection	961530
31206350	31206373	17	+	26627737	GBM cells	viability after 13 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	-0.23286104273188907	[378]	[217,139]	-3	hSpCas9	negative selection	961531
31232842	31232865	17	+	26627737	GBM cells	viability after 13 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.47477561338291707	[901]	[801,580]	6	hSpCas9	negative selection	961532
31095325	31095348	17	-	26627737	GBM cells	viability after 21 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-1.786360760025507	[285]	[43,45]	-8	hSpCas9	negative selection	1043842
31156021	31156044	17	+	26627737	GBM cells	viability after 21 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.07853823197642285	[370]	[204,219]	0	hSpCas9	negative selection	1043843
31163265	31163288	17	-	26627737	GBM cells	viability after 21 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.6876461949927086	[315]	[287,265]	7	hSpCas9	negative selection	1043844
31182620	31182643	17	+	26627737	GBM cells	viability after 21 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.39836429185860567	[548]	[413,373]	4	hSpCas9	negative selection	1043845
31206350	31206373	17	+	26627737	GBM cells	viability after 21 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	-0.9752438688697556	[378]	[110,98]	-7	hSpCas9	negative selection	1043846
31232842	31232865	17	+	26627737	GBM cells	viability after 21 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.34358226248859935	[901]	[637,606]	3	hSpCas9	negative selection	1043847
31095325	31095348	17	-	26627737	RPE1	viability after 9 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.7435286141053861	[390]	[66,80]	-5	hSpCas9	negative selection	1126157
31156021	31156044	17	+	26627737	RPE1	viability after 9 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	1.4437248599070722	[1750]	[1302,1733]	7	hSpCas9	negative selection	1126158
31163265	31163288	17	-	26627737	RPE1	viability after 9 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	1.266309458403765	[1746]	[1219,1438]	7	hSpCas9	negative selection	1126159
31182620	31182643	17	+	26627737	RPE1	viability after 9 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.6981172762464327	[1814]	[796,1082]	4	hSpCas9	negative selection	1126160
31206350	31206373	17	+	26627737	RPE1	viability after 9 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	1.0835173269567182	[1034]	[804,533]	6	hSpCas9	negative selection	1126161
31232842	31232865	17	+	26627737	RPE1	viability after 9 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	1.2225042743918144	[2521]	[1600,2153]	7	hSpCas9	negative selection	1126162
31095325	31095348	17	-	26627737	RPE1	viability after 12 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.19449113710776866	[390]	[67,116]	-1	hSpCas9	negative selection	1208472
31156021	31156044	17	+	26627737	RPE1	viability after 12 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	1.785324902343631	[1750]	[1487,1762]	8	hSpCas9	negative selection	1208473
31163265	31163288	17	-	26627737	RPE1	viability after 12 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	1.3899571415859933	[1746]	[1418,1029]	7	hSpCas9	negative selection	1208474
31182620	31182643	17	+	26627737	RPE1	viability after 12 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.924023586226987	[1814]	[558,1312]	6	hSpCas9	negative selection	1208475
31206350	31206373	17	+	26627737	RPE1	viability after 12 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	1.4428297321418948	[1034]	[804,703]	7	hSpCas9	negative selection	1208476
31232842	31232865	17	+	26627737	RPE1	viability after 12 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	1.5737950918214691	[2521]	[2018,2014]	8	hSpCas9	negative selection	1208477
31095325	31095348	17	-	26627737	RPE1	viability after 15 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.6146325822017651	[390]	[64,269]	4	hSpCas9	negative selection	1290787
31156021	31156044	17	+	26627737	RPE1	viability after 15 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	2.2799676485971094	[1750]	[2652,2166]	9	hSpCas9	negative selection	1290788
31163265	31163288	17	-	26627737	RPE1	viability after 15 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	2.1008858010813602	[1746]	[2826,1437]	8	hSpCas9	negative selection	1290789
31182620	31182643	17	+	26627737	RPE1	viability after 15 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.5168936576294922	[1814]	[1171,1755]	7	hSpCas9	negative selection	1290790
31206350	31206373	17	+	26627737	RPE1	viability after 15 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	2.027002133185352	[1034]	[1460,934]	8	hSpCas9	negative selection	1290791
31232842	31232865	17	+	26627737	RPE1	viability after 15 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	1.7649715105077939	[2521]	[2442,2406]	8	hSpCas9	negative selection	1290792
31095325	31095348	17	-	26627737	RPE1	viability after 18 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.6739288511663837	[390]	[192,141]	4	hSpCas9	negative selection	1373102
31156021	31156044	17	+	26627737	RPE1	viability after 18 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	2.4325654766524454	[1750]	[2405,2705]	9	hSpCas9	negative selection	1373103
31163265	31163288	17	-	26627737	RPE1	viability after 18 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	2.5641810653572614	[1746]	[3321,2217]	9	hSpCas9	negative selection	1373104
31182620	31182643	17	+	26627737	RPE1	viability after 18 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.8848722213810523	[1814]	[1341,2307]	8	hSpCas9	negative selection	1373105
31206350	31206373	17	+	26627737	RPE1	viability after 18 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	1.6586477158673523	[1034]	[964,792]	8	hSpCas9	negative selection	1373106
31232842	31232865	17	+	26627737	RPE1	viability after 18 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	1.9196007216418987	[2521]	[2745,2391]	8	hSpCas9	negative selection	1373107
31095325	31095348	17	-	26627737	HeLa	viability after 8 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-1.5605544951192143	[611]	[135,55,88]	-9	hSpCas9	negative selection	1455417
31156021	31156044	17	+	26627737	HeLa	viability after 8 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.024034659469669206	[712]	[472,287,198]	0	hSpCas9	negative selection	1455418
31163265	31163288	17	-	26627737	HeLa	viability after 8 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.26774998468350975	[749]	[409,505,274]	2	hSpCas9	negative selection	1455419
31182620	31182643	17	+	26627737	HeLa	viability after 8 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.04364524900087097	[1016]	[583,203,526]	0	hSpCas9	negative selection	1455420
31206350	31206373	17	+	26627737	HeLa	viability after 8 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	0.42569514781502127	[525]	[348,208,368]	4	hSpCas9	negative selection	1455421
31232842	31232865	17	+	26627737	HeLa	viability after 8 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.8937891992656675	[1072]	[893,692,1010]	7	hSpCas9	negative selection	1455422
31095325	31095348	17	-	26627737	HeLa	viability after 12 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-2.0872679694940963	[611]	[2,86,83]	-9	hSpCas9	negative selection	1537732
31156021	31156044	17	+	26627737	HeLa	viability after 12 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.2509191753219151	[712]	[220,483,328]	2	hSpCas9	negative selection	1537733
31163265	31163288	17	-	26627737	HeLa	viability after 12 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.6933369950499074	[749]	[212,521,757]	5	hSpCas9	negative selection	1537734
31182620	31182643	17	+	26627737	HeLa	viability after 12 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.30088916297854484	[1016]	[623,473,462]	2	hSpCas9	negative selection	1537735
31206350	31206373	17	+	26627737	HeLa	viability after 12 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	0.9948898472676805	[525]	[649,177,504]	7	hSpCas9	negative selection	1537736
31232842	31232865	17	+	26627737	HeLa	viability after 12 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.6935919190996449	[1072]	[587,761,792]	5	hSpCas9	negative selection	1537737
31095325	31095348	17	-	26627737	HeLa	viability after 15 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-1.5437356822781036	[611]	[130,84,35]	-8	hSpCas9	negative selection	1620047
31156021	31156044	17	+	26627737	HeLa	viability after 15 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.2902278729040486	[712]	[182,565,314]	2	hSpCas9	negative selection	1620048
31163265	31163288	17	-	26627737	HeLa	viability after 15 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.46138811045869665	[749]	[265,433,574]	4	hSpCas9	negative selection	1620049
31182620	31182643	17	+	26627737	HeLa	viability after 15 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.3559920065869684	[1016]	[558,479,551]	3	hSpCas9	negative selection	1620050
31206350	31206373	17	+	26627737	HeLa	viability after 15 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	0.5376154864772315	[525]	[337,417,164]	4	hSpCas9	negative selection	1620051
31232842	31232865	17	+	26627737	HeLa	viability after 15 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.7415851614992097	[1072]	[576,439,1212]	6	hSpCas9	negative selection	1620052
31095325	31095348	17	-	26627737	HeLa	viability after 18 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-1.5629792659513728	[611]	[85,69,35]	-8	hSpCas9	negative selection	1702362
31156021	31156044	17	+	26627737	HeLa	viability after 18 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.2970716420451507	[712]	[124,469,314]	2	hSpCas9	negative selection	1702363
31163265	31163288	17	-	26627737	HeLa	viability after 18 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.474790752347792	[749]	[183,361,574]	4	hSpCas9	negative selection	1702364
31182620	31182643	17	+	26627737	HeLa	viability after 18 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.3957054992315201	[1016]	[404,395,551]	3	hSpCas9	negative selection	1702365
31206350	31206373	17	+	26627737	HeLa	viability after 18 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	0.5563936298337158	[525]	[229,351,164]	4	hSpCas9	negative selection	1702366
31232842	31232865	17	+	26627737	HeLa	viability after 18 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.7413684843999913	[1072]	[383,367,1212]	6	hSpCas9	negative selection	1702367
31095325	31095348	17	-	26627737	HCT116	viability after 6 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.2987060935463419	[517]	[178,3]	-2	hSpCas9	negative selection	1784677
31156021	31156044	17	+	26627737	HCT116	viability after 6 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.8583746338272223	[888]	[108,332]	5	hSpCas9	negative selection	1784678
31163265	31163288	17	-	26627737	HCT116	viability after 6 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.33560443537365925	[712]	[134,144]	2	hSpCas9	negative selection	1784679
31182620	31182643	17	+	26627737	HCT116	viability after 6 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.5100459553623213	[1011]	[219,51]	-3	hSpCas9	negative selection	1784680
31206350	31206373	17	+	26627737	HCT116	viability after 6 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	0.15431558730411732	[1206]	[526,36]	0	hSpCas9	negative selection	1784681
31232842	31232865	17	+	26627737	HCT116	viability after 6 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.31127249469391094	[2608]	[865,311]	1	hSpCas9	negative selection	1784682
31095325	31095348	17	-	26627737	HCT116	viability after 8 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.8192508908581029	[295]	[82,89,103]	-7	hSpCas9	negative selection	1866992
31156021	31156044	17	+	26627737	HCT116	viability after 8 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.04813574107963292	[584]	[322,369,306]	0	hSpCas9	negative selection	1866993
31163265	31163288	17	-	26627737	HCT116	viability after 8 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	-0.2256589024760367	[477]	[284,180,210]	-3	hSpCas9	negative selection	1866994
31182620	31182643	17	+	26627737	HCT116	viability after 8 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.14402049515704307	[572]	[235,306,312]	-2	hSpCas9	negative selection	1866995
31206350	31206373	17	+	26627737	HCT116	viability after 8 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	-0.009786820265281854	[351]	[171,164,239]	0	hSpCas9	negative selection	1866996
31232842	31232865	17	+	26627737	HCT116	viability after 8 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.35778310929855484	[948]	[664,656,687]	4	hSpCas9	negative selection	1866997
31095325	31095348	17	-	26627737	HCT116	viability after 9 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-1.0070662665488688	[517]	[122,25]	-6	hSpCas9	negative selection	1949307
31156021	31156044	17	+	26627737	HCT116	viability after 9 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.436574500480247	[888]	[204,151]	-3	hSpCas9	negative selection	1949308
31163265	31163288	17	-	26627737	HCT116	viability after 9 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	1.5398236762139452	[712]	[862,308]	8	hSpCas9	negative selection	1949309
31182620	31182643	17	+	26627737	HCT116	viability after 9 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.1319009875789975	[1011]	[359,156]	-1	hSpCas9	negative selection	1949310
31206350	31206373	17	+	26627737	HCT116	viability after 9 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	0.14748729904983526	[1206]	[380,337]	1	hSpCas9	negative selection	1949311
31232842	31232865	17	+	26627737	HCT116	viability after 9 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.17483801047546432	[2608]	[772,796]	1	hSpCas9	negative selection	1949312
31095325	31095348	17	-	26627737	HCT116	viability after 12 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.10173192129375294	[295]	[132,105,195]	-1	hSpCas9	negative selection	2031622
31156021	31156044	17	+	26627737	HCT116	viability after 12 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.3499177558622212	[584]	[425,372,372]	3	hSpCas9	negative selection	2031623
31163265	31163288	17	-	26627737	HCT116	viability after 12 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	-0.07794439536310271	[477]	[243,260,208]	-1	hSpCas9	negative selection	2031624
31182620	31182643	17	+	26627737	HCT116	viability after 12 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.53614591430451	[572]	[179,231,213]	-5	hSpCas9	negative selection	2031625
31206350	31206373	17	+	26627737	HCT116	viability after 12 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	0.39559260156651993	[351]	[334,243,142]	4	hSpCas9	negative selection	2031626
31232842	31232865	17	+	26627737	HCT116	viability after 12 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.23198171835995107	[948]	[549,778,435]	2	hSpCas9	negative selection	2031627
31095325	31095348	17	-	26627737	HCT116	viability after 15 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.04834472480046344	[295]	[262,101,172]	0	hSpCas9	negative selection	2113937
31156021	31156044	17	+	26627737	HCT116	viability after 15 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.05205551952273868	[584]	[386,282,309]	0	hSpCas9	negative selection	2113938
31163265	31163288	17	-	26627737	HCT116	viability after 15 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	-0.09878162419899816	[477]	[255,339,173]	-1	hSpCas9	negative selection	2113939
31182620	31182643	17	+	26627737	HCT116	viability after 15 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.2528807679444389	[572]	[599,238,362]	2	hSpCas9	negative selection	2113940
31206350	31206373	17	+	26627737	HCT116	viability after 15 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	0.8727066179044691	[351]	[638,366,139]	7	hSpCas9	negative selection	2113941
31232842	31232865	17	+	26627737	HCT116	viability after 15 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.5315267791102516	[948]	[765,748,844]	5	hSpCas9	negative selection	2113942
31095325	31095348	17	-	26627737	HCT116	viability after 18 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.35037234812095847	[295]	[108,103,346]	3	hSpCas9	negative selection	2196252
31156021	31156044	17	+	26627737	HCT116	viability after 18 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.4763233161603865	[584]	[426,262,503]	4	hSpCas9	negative selection	2196253
31163265	31163288	17	-	26627737	HCT116	viability after 18 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	-0.11183418762500441	[477]	[265,162,215]	-1	hSpCas9	negative selection	2196254
31182620	31182643	17	+	26627737	HCT116	viability after 18 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.5529466547475257	[572]	[215,155,196]	-5	hSpCas9	negative selection	2196255
31206350	31206373	17	+	26627737	HCT116	viability after 18 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	1.2687432656432844	[351]	[709,364,145]	8	hSpCas9	negative selection	2196256
31232842	31232865	17	+	26627737	HCT116	viability after 18 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.711984096094785	[948]	[704,869,667]	6	hSpCas9	negative selection	2196257
31095302	31095325	17	+	24336569	HL60	viability	GGGAGGACATGGCCGCGCACAGG	NF1	ENSG00000196712	0.6489015047134205	[722]	[2398]	5	hSpCas9	negative selection	2279912
31095309	31095332	17	+	24336569	HL60	viability	CATGGCCGCGCACAGGCCGGTGG	NF1	ENSG00000196712	0.7397852630870885	[619]	[2190]	6	hSpCas9	negative selection	2279913
31095314	31095337	17	-	24336569	HL60	viability	CCATTCCACCGGCCTGTGCGCGG	NF1	ENSG00000196712	-0.03706998127044292	[431]	[890]	0	hSpCas9	negative selection	2279914
31095321	31095344	17	+	24336569	HL60	viability	CAGGCCGGTGGAATGGGTCCAGG	NF1	ENSG00000196712	0.05331707083656624	[433]	[952]	0	hSpCas9	negative selection	2279915
31095327	31095350	17	+	24336569	HL60	viability	GGTGGAATGGGTCCAGGCCGTGG	NF1	ENSG00000196712	1.5546027410402656	[207]	[1292]	9	hSpCas9	negative selection	2279916
31095339	31095362	17	-	24336569	HL60	viability	CGAAGCGGCTGACCACGGCCTGG	NF1	ENSG00000196712	0.3610541350720545	[194]	[529]	3	hSpCas9	negative selection	2279917
31095344	31095367	17	-	24336569	HL60	viability	CTCGTCGAAGCGGCTGACCACGG	NF1	ENSG00000196712	0.5866923356186586	[437]	[1391]	5	hSpCas9	negative selection	2279918
31095354	31095377	17	-	24336569	HL60	viability	CGGTTACCTGCTCGTCGAAGCGG	NF1	ENSG00000196712	-0.07401599404547729	[482]	[970]	0	hSpCas9	negative selection	2279919
31156017	31156040	17	-	24336569	HL60	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	2.6620714264189225	[240]	[3227]	9	hSpCas9	negative selection	2279920
31159045	31159068	17	+	24336569	HL60	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	-0.4226141754537769	[424]	[670]	-4	hSpCas9	negative selection	2279921
31095302	31095325	17	+	24336569	KBM7	viability	GGGAGGACATGGCCGCGCACAGG	NF1	ENSG00000196712	-0.3052157027428119	[457]	[1010]	-3	hSpCas9	negative selection	2347089
31095309	31095332	17	+	24336569	KBM7	viability	CATGGCCGCGCACAGGCCGGTGG	NF1	ENSG00000196712	-1.161982636062997	[570]	[695]	-7	hSpCas9	negative selection	2347090
31095314	31095337	17	-	24336569	KBM7	viability	CCATTCCACCGGCCTGTGCGCGG	NF1	ENSG00000196712	0.2502600663275024	[298]	[969]	2	hSpCas9	negative selection	2347091
31095321	31095344	17	+	24336569	KBM7	viability	CAGGCCGGTGGAATGGGTCCAGG	NF1	ENSG00000196712	-0.3644088161886689	[395]	[838]	-3	hSpCas9	negative selection	2347092
31095327	31095350	17	+	24336569	KBM7	viability	GGTGGAATGGGTCCAGGCCGTGG	NF1	ENSG00000196712	0.7774667017925123	[193]	[906]	7	hSpCas9	negative selection	2347093
31095339	31095362	17	-	24336569	KBM7	viability	CGAAGCGGCTGACCACGGCCTGG	NF1	ENSG00000196712	0.023840772627480078	[206]	[573]	0	hSpCas9	negative selection	2347094
31095344	31095367	17	-	24336569	KBM7	viability	CTCGTCGAAGCGGCTGACCACGG	NF1	ENSG00000196712	1.3720020278419809	[234]	[1658]	9	hSpCas9	negative selection	2347095
31095354	31095377	17	-	24336569	KBM7	viability	CGGTTACCTGCTCGTCGAAGCGG	NF1	ENSG00000196712	0.36634837943220777	[218]	[769]	3	hSpCas9	negative selection	2347096
31156017	31156040	17	-	24336569	KBM7	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.5258402043478005	[492]	[1935]	5	hSpCas9	negative selection	2347097
31159045	31159068	17	+	24336569	KBM7	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.6453484051782681	[247]	[1057]	6	hSpCas9	negative selection	2347098
31102384	31102407	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGCTCTGTCACTCAGGCTAG	NF1	ENSG00000196712	-0.9680761470245136	[202,921]	[9,121]	-5	dCas9-VP64	positive selection	2407045
31161881	31161904	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCCAGATGTGGTGG	NF1	ENSG00000196712	-1.3435530862005833	[526,335]	[46,25]	-7	dCas9-VP64	positive selection	2413593
31184618	31184641	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGTCTCGCTGTCGCCCAGGCTGG	NF1	ENSG00000196712	0.8346262078071658	[10,1]	[2,1]	3	dCas9-VP64	positive selection	2416343
31234437	31234460	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGAGGCGGGAGGATCACAAGG	NF1	ENSG00000196712	3.278703021819371	[41,15]	[74,47]	8	dCas9-VP64	positive selection	2449176
31341313	31341336	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGTTAGAGAACAGCCTGG	NF1	ENSG00000196712	0.09483238765426616	[27,66]	[9,11]	0	dCas9-VP64	positive selection	2456243
31173083	31173106	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCCCCATGTTGGCCAGGCTGG	NF1	ENSG00000196712	-2.3967661507972187	[409,3]	[13,1]	-9	dCas9-VP64	positive selection	2461882
31102384	31102407	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGCTCTGTCACTCAGGCTAG	NF1	ENSG00000196712	-0.6011121662635273	[131,74]	[29,13]	-6	dCas9-VP64	positive selection	2502300
31161881	31161904	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCCAGATGTGGTGG	NF1	ENSG00000196712	0.12779844081241276	[54,202]	[74,16]	1	dCas9-VP64	positive selection	2508848
31184618	31184641	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGTCTCGCTGTCGCCCAGGCTGG	NF1	ENSG00000196712	-1.711674582430177	[43,184]	[8,12]	-9	dCas9-VP64	positive selection	2511598
31234437	31234460	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGAGGCGGGAGGATCACAAGG	NF1	ENSG00000196712	0.5394300049106193	[35,34]	[25,7]	4	dCas9-VP64	positive selection	2544431
31341313	31341336	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGTTAGAGAACAGCCTGG	NF1	ENSG00000196712	-0.6333222903590552	[146,29]	[8,26]	-6	dCas9-VP64	positive selection	2551498
31173083	31173106	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCCCCATGTTGGCCAGGCTGG	NF1	ENSG00000196712	-0.19517249926292646	[17,29]	[9,2]	-2	dCas9-VP64	positive selection	2557137
31182621	31182644	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.710015230614643	[3,3]	[4,5]	9	hSpCas9	positive selection	3005376
31163310	31163333	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	0.23678330808523274	[4,4]	[4,4]	5	hSpCas9	positive selection	3005377
31095328	31095351	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGGAATGGGTCCAGGCCGTGG	NF1	ENSG00000196712	-1.9044964444839247	[3,3]	[0,0]	-9	hSpCas9	positive selection	3005378
31163356	31163379	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.09226923618721772	[5,5]	[5,3]	2	hSpCas9	positive selection	3005379
31182621	31182644	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.2789523420003186	[3,3]	[3,0]	-4	hSpCas9	positive selection	3073234
31163310	31163333	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	0.2265274073452564	[4,4]	[4,3]	4	hSpCas9	positive selection	3073235
31095328	31095351	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGGAATGGGTCCAGGCCGTGG	NF1	ENSG00000196712	-0.4611096798456825	[3,3]	[3,0]	-6	hSpCas9	positive selection	3073236
31163356	31163379	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.22214670545235338	[5,5]	[5,3]	4	hSpCas9	positive selection	3073237
31159070	31159093		+	24336571	A375	resistance to PLX after 7 days	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.308500977730372	[24,28]	[37,27]	8	hSpCas9	positive selection	3130423
31156017	31156040		-	24336571	A375	resistance to PLX after 7 days	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	3.2196834319904326	[119,52]	[814,793]	9	hSpCas9	positive selection	3130424
31159070	31159093		+	24336571	A375	resistance to PLX after 14 days	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	6.264931886092492	[26,27]	[788,1215]	9	hSpCas9	positive selection	3188216
31156017	31156040		-	24336571	A375	resistance to PLX after 14 days	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	10.92567223927658	[140,36]	[80606,82278]	10	hSpCas9	positive selection	3188217
31159070	31159093		+	24336571	A375	viability after 7 days	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.08196761958793075	[26]	[24,28]	1	hSpCas9	negative selection	3246009
31156017	31156040		-	24336571	A375	viability after 7 days	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	1.135009736560224	[40]	[119,52]	9	hSpCas9	negative selection	3246010
31159070	31159093		+	24336571	A375	viability after 14 days	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.12628903025398575	[26]	[26,27]	1	hSpCas9	negative selection	3303802
31156017	31156040		-	24336571	A375	viability after 14 days	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	1.195514520279716	[40]	[140,36]	9	hSpCas9	negative selection	3303803
31156021	31156044	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-1.4908666381436253	[429,429]	[0,0]	-8	hSpCas9	positive selection	3381547
31156017	31156040	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-1.181465641132426	[346,346]	[0,0]	-7	hSpCas9	positive selection	3381548
31159045	31159068	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	-1.05555674383852	[317,317]	[0,0]	-7	hSpCas9	positive selection	3381549
31182620	31182643	17	+	26780180	HT29	viability (Avana library 4 designs)	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.980385198625213	[]	[]	-9	hSpCas9	negative selection	3443212
31163310	31163333	17	-	26780180	HT29	viability (Avana library 4 designs)	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	-1.91198026207811	[]	[]	-9	hSpCas9	negative selection	3443213
31095327	31095350	17	+	26780180	HT29	viability (Avana library 4 designs)	GGTGGAATGGGTCCAGGCCGTGG	NF1	ENSG00000196712	-0.763025339542305	[]	[]	-8	hSpCas9	negative selection	3443214
31163355	31163378	17	+	26780180	HT29	viability (Avana library 4 designs)	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	-1.04635108109114	[]	[]	-9	hSpCas9	negative selection	3443215
31163310	31163333	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	-1.27954643927016	[]	[]	-1	hSpCas9	negative selection	3534792
31182620	31182643	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.07369421742298	[]	[]	1	hSpCas9	negative selection	3534793
31095327	31095350	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGAATGGGTCCAGGCCGTGG	NF1	ENSG00000196712	4.27729520246499	[]	[]	7	hSpCas9	negative selection	3534794
31163355	31163378	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	1.75716277296631	[]	[]	2	hSpCas9	negative selection	3534795
31156093	31156116	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATTCTTTAAAATAGTAGTGAGG	NF1	ENSG00000196712	-0.492726414873233	[]	[]	0	hSpCas9	negative selection	3534796
31163280	31163303	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCAGCATGCAGCTGAACTTCGG	NF1	ENSG00000196712	5.4101635057577	[]	[]	8	hSpCas9	negative selection	3534797
31163310	31163333	17	-	26780180	A375	viability (Avana lentiGuide)	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	-5.37550301892053	[]	[]	-8	hSpCas9	negative selection	3643451
31182620	31182643	17	+	26780180	A375	viability (Avana lentiGuide)	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.594957665019938	[]	[]	-1	hSpCas9	negative selection	3643452
31095327	31095350	17	+	26780180	A375	viability (Avana lentiGuide)	GGTGGAATGGGTCCAGGCCGTGG	NF1	ENSG00000196712	11.6208020146214	[]	[]	7	hSpCas9	negative selection	3643453
31163355	31163378	17	+	26780180	A375	viability (Avana lentiGuide)	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	1.14768322638369	[]	[]	1	hSpCas9	negative selection	3643454
31156093	31156116	17	-	26780180	A375	viability (Avana lentiGuide)	CATTCTTTAAAATAGTAGTGAGG	NF1	ENSG00000196712	-5.58053792676006	[]	[]	-8	hSpCas9	negative selection	3643455
31163280	31163303	17	+	26780180	A375	viability (Avana lentiGuide)	ACCAGCATGCAGCTGAACTTCGG	NF1	ENSG00000196712	-0.30593154512045	[]	[]	0	hSpCas9	negative selection	3643456
31163310	31163333	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	1.11998643923007	[6]	[13,14]	9	hSpCas9	positive selection	3752110
31182620	31182643	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.322926253787036	[4]	[12,13]	9	hSpCas9	positive selection	3752111
31095327	31095350	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGAATGGGTCCAGGCCGTGG	NF1	ENSG00000196712	1.349449736216926	[4]	[12,14]	9	hSpCas9	positive selection	3752112
31163355	31163378	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.8414345297208947	[6]	[9,13]	9	hSpCas9	positive selection	3752113
31156093	31156116	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTCTTTAAAATAGTAGTGAGG	NF1	ENSG00000196712	0.7101681748520476	[9]	[14,16]	9	hSpCas9	positive selection	3752114
31163280	31163303	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCAGCATGCAGCTGAACTTCGG	NF1	ENSG00000196712	1.3303869811326747	[4]	[11,13]	9	hSpCas9	positive selection	3752115
31163310	31163333	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	0.897729705067785	[5]	[8,10]	9	hSpCas9	positive selection	3860717
31182620	31182643	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.5561456177982144	[5]	[5,7]	9	hSpCas9	positive selection	3860718
31095327	31095350	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGAATGGGTCCAGGCCGTGG	NF1	ENSG00000196712	0.45470018174151355	[5]	[4,8]	9	hSpCas9	positive selection	3860719
31163355	31163378	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.995928926313949	[6]	[12,12]	9	hSpCas9	positive selection	3860720
31156093	31156116	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTCTTTAAAATAGTAGTGAGG	NF1	ENSG00000196712	1.2498090633713654	[5]	[12,11]	9	hSpCas9	positive selection	3860721
31163280	31163303	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCAGCATGCAGCTGAACTTCGG	NF1	ENSG00000196712	1.016748081589571	[5]	[11,9]	9	hSpCas9	positive selection	3860722
31159070	31159093	17	+	26780180	A375	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.439802409010235	[]	[]	1	hSpCas9	negative selection	3972048
31156021	31156044	17	+	26780180	A375	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.0448600598292774	[]	[]	0	hSpCas9	negative selection	3972049
31156017	31156040	17	-	26780180	A375	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	1.05321581874837	[]	[]	5	hSpCas9	negative selection	3972050
31159045	31159068	17	+	26780180	A375	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	1.1877773215224	[]	[]	6	hSpCas9	negative selection	3972051
31163355	31163378	17	+	26780180	A375	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	1.07219135220083	[]	[]	5	hSpCas9	negative selection	3972052
31163255	31163278	17	+	26780180	A375	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.654388604723871	[]	[]	2	hSpCas9	negative selection	3972053
31159070	31159093	17	+	26780180	HT29	viability (GeCKOv2 library)	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.390029932168381	[]	[]	1	hSpCas9	negative selection	4080014
31156021	31156044	17	+	26780180	HT29	viability (GeCKOv2 library)	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.541745757000561	[]	[]	-9	hSpCas9	negative selection	4080015
31156017	31156040	17	-	26780180	HT29	viability (GeCKOv2 library)	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.186354515252514	[]	[]	0	hSpCas9	negative selection	4080016
31159045	31159068	17	+	26780180	HT29	viability (GeCKOv2 library)	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.874009956312943	[]	[]	3	hSpCas9	negative selection	4080017
31163355	31163378	17	+	26780180	HT29	viability (GeCKOv2 library)	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.259623476299651	[]	[]	0	hSpCas9	negative selection	4080018
31163255	31163278	17	+	26780180	HT29	viability (GeCKOv2 library)	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.837792825746994	[]	[]	3	hSpCas9	negative selection	4080019
31159070	31159093	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	1.278019604966774	[4]	[5,9]	9	hSpCas9	positive selection	4155077
31156017	31156040	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	1.8592314070438576	[5]	[13,16]	9	hSpCas9	positive selection	4155078
31159070	31159093	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	2.380340709690615	[5]	[15,11,13,11]	9	hSpCas9	positive selection	4219099
31156017	31156040	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	2.265489499405531	[8]	[17,17,17,17]	9	hSpCas9	positive selection	4219100
31163355	31163378	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	1.5611261987272411	[3]	[10,10]	9	hSpCas9	positive selection	4285413
31159070	31159093	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.7936681588055118	[3]	[4,5]	9	hSpCas9	positive selection	4285414
31163255	31163278	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.5583483285499142	[3]	[3,4]	9	hSpCas9	positive selection	4285415
31156021	31156044	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	1.7760780407779504	[4]	[11,13]	9	hSpCas9	positive selection	4349671
31156017	31156040	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	1.5473912543180597	[4]	[10,10]	9	hSpCas9	positive selection	4349672
31159045	31159068	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.34061854595533214	[3]	[4,3]	7	hSpCas9	positive selection	4349673
31163281	31163303	17	-	27760321	OCIAML3	viability	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	0.15308004737652847	[934,774]	[606,913]	1	hSpCas9	negative selection	4422055
31163356	31163378	17	+	27760321	OCIAML3	viability	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	-0.07185118270997198	[390,330]	[248,291]	-1	hSpCas9	negative selection	4422056
31169977	31169999	17	+	27760321	OCIAML3	viability	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	0.3925822972595179	[76,56]	[65,70]	5	hSpCas9	negative selection	4422057
31181463	31181485	17	+	27760321	OCIAML3	viability	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	0.6515196971492956	[48,43]	[40,77]	7	hSpCas9	negative selection	4422058
31181760	31181782	17	-	27760321	OCIAML3	viability	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	0.09648243938630019	[1485,1219]	[1029,1250]	1	hSpCas9	negative selection	4422059
31163281	31163303	17	-	27760321	OCIAML2	viability	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	0.08131066298214595	[934,774]	[627,860]	1	hSpCas9	negative selection	4505518
31163356	31163378	17	+	27760321	OCIAML2	viability	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.42328663592982185	[390,330]	[356,433]	6	hSpCas9	negative selection	4505519
31169977	31169999	17	+	27760321	OCIAML2	viability	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	-0.7774847414872541	[76,56]	[23,40]	-7	hSpCas9	negative selection	4505520
31181463	31181485	17	+	27760321	OCIAML2	viability	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	0.5394180761240994	[48,43]	[48,61]	7	hSpCas9	negative selection	4505521
31181760	31181782	17	-	27760321	OCIAML2	viability	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	-0.08433906142059167	[1485,1219]	[859,1247]	-1	hSpCas9	negative selection	4505522
31163281	31163303	17	-	27760321	MV411	viability	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	0.3881027487818266	[934,774]	[886,506]	2	hSpCas9	negative selection	4588981
31163356	31163378	17	+	27760321	MV411	viability	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	1.01533333545464	[390,330]	[281,776]	7	hSpCas9	negative selection	4588982
31169977	31169999	17	+	27760321	MV411	viability	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	-1.3659516791890627	[76,56]	[16,16]	-7	hSpCas9	negative selection	4588983
31181463	31181485	17	+	27760321	MV411	viability	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	-3.012732454122373	[48,43]	[0,7]	-9	hSpCas9	negative selection	4588984
31181760	31181782	17	-	27760321	MV411	viability	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	0.6480445264172356	[1485,1219]	[1431,1332]	5	hSpCas9	negative selection	4588985
31163281	31163303	17	-	27760321	HL60	viability	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	0.0019872680710583124	[934,774]	[623,772]	0	hSpCas9	negative selection	4672444
31163356	31163378	17	+	27760321	HL60	viability	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.4162994343746517	[390,330]	[313,474]	5	hSpCas9	negative selection	4672445
31169977	31169999	17	+	27760321	HL60	viability	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	0.633832627298704	[76,56]	[72,95]	7	hSpCas9	negative selection	4672446
31181463	31181485	17	+	27760321	HL60	viability	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	-0.1809831784714988	[48,43]	[48,16]	-2	hSpCas9	negative selection	4672447
31181760	31181782	17	-	27760321	HL60	viability	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	0.3476182843994231	[1485,1219]	[1254,1552]	4	hSpCas9	negative selection	4672448
31163281	31163303	17	-	27760321	HT1080	viability	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	2.571566756273598	[774,604]	[2245,963]	9	hSpCas9	negative selection	4755907
31163356	31163378	17	+	27760321	HT1080	viability	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	1.4020788921991558	[330,257]	[257,366]	7	hSpCas9	negative selection	4755908
31169977	31169999	17	+	27760321	HT1080	viability	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	-0.6104284831868663	[56,44]	[19,5]	-3	hSpCas9	negative selection	4755909
31181463	31181485	17	+	27760321	HT1080	viability	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	-0.6234256910396105	[43,34]	[14,4]	-3	hSpCas9	negative selection	4755910
31181760	31181782	17	-	27760321	HT1080	viability	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	0.9816166897701586	[1219,951]	[986,708]	5	hSpCas9	negative selection	4755911
31163281	31163303	17	-	27760321	HT29	viability after 7 days	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	-0.057342304698010604	[774,604]	[1172,601,827]	-1	hSpCas9	negative selection	4839370
31163356	31163378	17	+	27760321	HT29	viability after 7 days	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.2949414464861372	[330,257]	[451,568,372]	4	hSpCas9	negative selection	4839371
31169977	31169999	17	+	27760321	HT29	viability after 7 days	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	0.4710951300037429	[56,44]	[29,77,153]	7	hSpCas9	negative selection	4839372
31181463	31181485	17	+	27760321	HT29	viability after 7 days	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	0.23472155146911966	[43,34]	[47,78,50]	3	hSpCas9	negative selection	4839373
31181760	31181782	17	-	27760321	HT29	viability after 7 days	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	-0.11189243278852223	[1219,951]	[1371,1261,1252]	-2	hSpCas9	negative selection	4839374
31163281	31163303	17	-	27760321	HT29	viability after 25 days	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	1.7673954009944826	[774,604]	[2384,2580,3150]	9	hSpCas9	negative selection	4922833
31163356	31163378	17	+	27760321	HT29	viability after 25 days	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.9410383661404005	[330,257]	[659,806,448]	9	hSpCas9	negative selection	4922834
31169977	31169999	17	+	27760321	HT29	viability after 25 days	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	1.6846836658372815	[56,44]	[154,223,184]	9	hSpCas9	negative selection	4922835
31181463	31181485	17	+	27760321	HT29	viability after 25 days	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	0.5201290387231694	[43,34]	[4,111,82]	6	hSpCas9	negative selection	4922836
31181760	31181782	17	-	27760321	HT29	viability after 25 days	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	1.286411118049152	[1219,951]	[2861,2893,3366]	9	hSpCas9	negative selection	4922837
31163281	31163303	17	-	27760321	HT29	viability after 22 days	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	1.6233312381195475	[774,604]	[2099,2325,2960]	9	hSpCas9	negative selection	5006296
31163356	31163378	17	+	27760321	HT29	viability after 22 days	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.6428026705649628	[330,257]	[444,506,645]	7	hSpCas9	negative selection	5006297
31169977	31169999	17	+	27760321	HT29	viability after 22 days	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	1.7963926339663772	[56,44]	[214,145,253]	9	hSpCas9	negative selection	5006298
31181463	31181485	17	+	27760321	HT29	viability after 22 days	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	-0.5582829290780222	[43,34]	[0,56,35]	-5	hSpCas9	negative selection	5006299
31181760	31181782	17	-	27760321	HT29	viability after 22 days	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	1.0545795752876663	[1219,951]	[2233,2590,3011]	9	hSpCas9	negative selection	5006300
31163281	31163303	17	-	27760321	HT29	viability after 19 days	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	1.189712307429247	[774,604]	[2063,1891,1482]	9	hSpCas9	negative selection	5089759
31163356	31163378	17	+	27760321	HT29	viability after 19 days	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	-0.10049367388726882	[330,257]	[284,336,316]	-1	hSpCas9	negative selection	5089760
31169977	31169999	17	+	27760321	HT29	viability after 19 days	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	1.6905030553596991	[56,44]	[120,301,136]	9	hSpCas9	negative selection	5089761
31181463	31181485	17	+	27760321	HT29	viability after 19 days	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	-0.5245988260105734	[43,34]	[20,61,10]	-4	hSpCas9	negative selection	5089762
31181760	31181782	17	-	27760321	HT29	viability after 19 days	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	0.7866604174276839	[1219,951]	[2285,2540,1633]	7	hSpCas9	negative selection	5089763
31163281	31163303	17	-	27760321	HT29	viability after 16 days	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	0.8853544630437441	[774,604]	[1539,1219,1533]	9	hSpCas9	negative selection	5173222
31163356	31163378	17	+	27760321	HT29	viability after 16 days	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.2001589442491603	[330,257]	[508,253,387]	2	hSpCas9	negative selection	5173223
31169977	31169999	17	+	27760321	HT29	viability after 16 days	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	1.0829151906260037	[56,44]	[154,84,126]	9	hSpCas9	negative selection	5173224
31181463	31181485	17	+	27760321	HT29	viability after 16 days	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	-0.09225156532615264	[43,34]	[42,27,53]	-1	hSpCas9	negative selection	5173225
31181760	31181782	17	-	27760321	HT29	viability after 16 days	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	0.6396647958083301	[1219,951]	[1965,1985,1730]	7	hSpCas9	negative selection	5173226
31163281	31163303	17	-	27760321	HT29	viability after 13 days	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	0.5466168211518404	[774,604]	[1082,1294,1131]	7	hSpCas9	negative selection	5256685
31163356	31163378	17	+	27760321	HT29	viability after 13 days	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	-0.3146433614919762	[330,257]	[187,306,325]	-4	hSpCas9	negative selection	5256686
31169977	31169999	17	+	27760321	HT29	viability after 13 days	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	1.3142136333067795	[56,44]	[190,161,91]	9	hSpCas9	negative selection	5256687
31181463	31181485	17	+	27760321	HT29	viability after 13 days	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	-1.2300644857416385	[43,34]	[0,25,30]	-8	hSpCas9	negative selection	5256688
31181760	31181782	17	-	27760321	HT29	viability after 13 days	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	0.6882634197104536	[1219,951]	[2204,2102,1795]	8	hSpCas9	negative selection	5256689
31163281	31163303	17	-	27760321	HT29	viability after 10 days	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	0.3617249466579996	[774,604]	[756,1065,1487]	5	hSpCas9	negative selection	5340148
31163356	31163378	17	+	27760321	HT29	viability after 10 days	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	-0.42541179704564974	[330,257]	[246,259,312]	-5	hSpCas9	negative selection	5340149
31169977	31169999	17	+	27760321	HT29	viability after 10 days	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	0.02385415790945178	[56,44]	[28,93,71]	0	hSpCas9	negative selection	5340150
31181463	31181485	17	+	27760321	HT29	viability after 10 days	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	-1.3765394225096959	[43,34]	[7,22,25]	-8	hSpCas9	negative selection	5340151
31181760	31181782	17	-	27760321	HT29	viability after 10 days	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	0.5168309065135555	[1219,951]	[1684,2437,1715]	7	hSpCas9	negative selection	5340152
31163281	31163303	17	-	27760321	MOLM13	viability	CCGAAGTTCAGCTGCATGCTGG	NF1	ENSG00000196712	-0.15003383588667896	[934,774]	[535,344]	-1	hSpCas9	negative selection	5423611
31163356	31163378	17	+	27760321	MOLM13	viability	CTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	-0.22407938096912539	[390,330]	[250,107]	-1	hSpCas9	negative selection	5423612
31169977	31169999	17	+	27760321	MOLM13	viability	AATTAAAACGACTCCTGAAGGG	NF1	ENSG00000196712	-2.3239476807382506	[76,56]	[0,12]	-8	hSpCas9	negative selection	5423613
31181463	31181485	17	+	27760321	MOLM13	viability	TTAGCAGTTATAAATAGCCTGG	NF1	ENSG00000196712	-0.08062358306929474	[48,43]	[20,27]	0	hSpCas9	negative selection	5423614
31181760	31181782	17	-	27760321	MOLM13	viability	CATATCAGTCTGTGGGATCTGG	NF1	ENSG00000196712	0.061685430299712074	[1485,1219]	[827,762]	0	hSpCas9	negative selection	5423615
31094996	31095019	17	+	27661255	K562	viability	GGCGGCGTCTCGGACTGTGATGG	NF1	ENSG00000196712	0.11751531769521245	[711,875]	[725,650]	4	dCas9-KRAB	negative selection	5496337
31095412	31095435	17	+	27661255	K562	viability	GTGGGGACAGAGTAGGTGAGGGG	NF1	ENSG00000196712	-0.18950470733077462	[636,860]	[530,513]	-6	dCas9-KRAB	negative selection	5496338
31094954	31094977	17	-	27661255	K562	viability	GGGATCCTTTCCACGGCCCGGGG	NF1	ENSG00000196712	-0.427652770883053	[1770,2050]	[1139,1124]	-7	dCas9-KRAB	negative selection	5496339
31163355	31163378	17	+	27260156	BXPC3	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.21787481950627896	[958]	[1111,1217,1113,1220]	5	hSpCas9	negative selection	5557873
31159070	31159093	17	+	27260156	BXPC3	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.25943465047078745	[649]	[668,919,826,845]	5	hSpCas9	negative selection	5557874
31163255	31163278	17	+	27260156	BXPC3	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.2231179979736554	[601]	[551,716,704,1014]	5	hSpCas9	negative selection	5557875
31156021	31156044	17	+	27260156	BXPC3	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.06440571193294775	[1066]	[919,940,1187,1260]	-1	hSpCas9	negative selection	5622131
31156017	31156040	17	-	27260156	BXPC3	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.21898209775688782	[995]	[955,811,874,931]	-5	hSpCas9	negative selection	5622132
31159045	31159068	17	+	27260156	BXPC3	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.1044272060872593	[768]	[859,873,902,807]	2	hSpCas9	negative selection	5622133
31163355	31163378	17	+	27260156	A673	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.4763260664782327	[958]	[1939,1529,1500,1467]	9	hSpCas9	negative selection	5679124
31159070	31159093	17	+	27260156	A673	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.2704582367090364	[649]	[1127,870,802,988]	6	hSpCas9	negative selection	5679125
31163255	31163278	17	+	27260156	A673	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.48371011246314455	[601]	[980,1073,989,989]	9	hSpCas9	negative selection	5679126
31156021	31156044	17	+	27260156	A673	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.008281632318812182	[1066]	[1256,1193,1239,1469]	0	hSpCas9	negative selection	5743382
31156017	31156040	17	-	27260156	A673	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.09306016425536257	[995]	[1201,1068,1093,1128]	-2	hSpCas9	negative selection	5743383
31159045	31159068	17	+	27260156	A673	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	-0.09134117911077244	[768]	[979,851,814,829]	-2	hSpCas9	negative selection	5743384
31163355	31163378	17	+	27260156	A375	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.6088672846558596	[958]	[1822,1872,1713,1468]	8	hSpCas9	negative selection	5800375
31159070	31159093	17	+	27260156	A375	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.37690814025943903	[649]	[1198,968,980,810]	5	hSpCas9	negative selection	5800376
31163255	31163278	17	+	27260156	A375	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.440542177099542	[601]	[867,1170,759,1033]	6	hSpCas9	negative selection	5800377
31156021	31156044	17	+	27260156	A375	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.022547147611699403	[1066]	[780,1548,1198,1394]	0	hSpCas9	negative selection	5864633
31156017	31156040	17	-	27260156	A375	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.18226311949847174	[995]	[1064,1345,835,908]	-3	hSpCas9	negative selection	5864634
31159045	31159068	17	+	27260156	A375	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.3817405780244094	[768]	[1373,1387,847,1105]	5	hSpCas9	negative selection	5864635
31163355	31163378	17	+	27260156	COLO741	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.24633619978256482	[958]	[1647,1421,1313]	5	hSpCas9	negative selection	5921626
31159070	31159093	17	+	27260156	COLO741	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.15767118983093525	[649]	[934,917,924]	3	hSpCas9	negative selection	5921627
31163255	31163278	17	+	27260156	COLO741	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.33243608759401133	[601]	[1072,1037,812]	7	hSpCas9	negative selection	5921628
31156021	31156044	17	+	27260156	COLO741	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.025136570755053933	[1066]	[1486,1557,1140]	0	hSpCas9	negative selection	5985884
31156017	31156040	17	-	27260156	COLO741	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.2309489846440479	[995]	[1252,1030,987]	-5	hSpCas9	negative selection	5985885
31159045	31159068	17	+	27260156	COLO741	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	-0.06939352622582773	[768]	[1015,906,893]	-1	hSpCas9	negative selection	5985886
31163355	31163378	17	+	27260156	CAL120	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.5827333693180317	[958]	[2287,1782,1372]	8	hSpCas9	negative selection	6042877
31159070	31159093	17	+	27260156	CAL120	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.3860677503372069	[649]	[1109,1032,1035]	6	hSpCas9	negative selection	6042878
31163255	31163278	17	+	27260156	CAL120	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.6776698798713179	[601]	[1048,1557,968]	8	hSpCas9	negative selection	6042879
31156021	31156044	17	+	27260156	CAL120	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	1.0304739689403488	[1066]	[3618,2055,2598]	9	hSpCas9	negative selection	6107135
31156017	31156040	17	-	27260156	CAL120	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.2593149149056797	[995]	[1594,1524,1348]	4	hSpCas9	negative selection	6107136
31159045	31159068	17	+	27260156	CAL120	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.2651937302368206	[768]	[1710,1005,822]	4	hSpCas9	negative selection	6107137
31163355	31163378	17	+	27260156	CADOES1	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.5324100651576751	[958]	[1198,1330,1605,1013]	8	hSpCas9	negative selection	6164128
31159070	31159093	17	+	27260156	CADOES1	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.4435752837099984	[649]	[716,960,818,790]	7	hSpCas9	negative selection	6164129
31163255	31163278	17	+	27260156	CADOES1	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.8337970780921118	[601]	[861,1003,1053,1074]	9	hSpCas9	negative selection	6164130
31156021	31156044	17	+	27260156	CADOES1	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.023120564187669723	[1066]	[1137,942,896,1056]	0	hSpCas9	negative selection	6228386
31156017	31156040	17	-	27260156	CADOES1	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.3735545874389876	[995]	[720,835,698,599]	-6	hSpCas9	negative selection	6228387
31159045	31159068	17	+	27260156	CADOES1	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.4349694348674171	[768]	[908,832,1065,1062]	7	hSpCas9	negative selection	6228388
31163355	31163378	17	+	27260156	EWS502	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.539313650869393	[958]	[1409,1192,1372,1976]	8	hSpCas9	negative selection	6285379
31159070	31159093	17	+	27260156	EWS502	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.4077830562621589	[649]	[808,1071,849,924]	7	hSpCas9	negative selection	6285380
31163255	31163278	17	+	27260156	EWS502	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.7222449381938882	[601]	[903,978,1081,1275]	9	hSpCas9	negative selection	6285381
31156021	31156044	17	+	27260156	EWS502	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.7816149710683788	[1066]	[1622,2166,1754,2268]	9	hSpCas9	negative selection	6349637
31156017	31156040	17	-	27260156	EWS502	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.27681727572833803	[995]	[1014,998,1269,1911]	5	hSpCas9	negative selection	6349638
31159045	31159068	17	+	27260156	EWS502	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.3178883318603478	[768]	[867,726,1118,1401]	5	hSpCas9	negative selection	6349639
31163355	31163378	17	+	27260156	EW8	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.378062379862252	[958]	[766,1410,894,958]	7	hSpCas9	negative selection	6406630
31159070	31159093	17	+	27260156	EW8	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.07907507157261501	[649]	[746,544,493,469]	1	hSpCas9	negative selection	6406631
31163255	31163278	17	+	27260156	EW8	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.4397303473683689	[601]	[782,475,638,762]	7	hSpCas9	negative selection	6406632
31156021	31156044	17	+	27260156	EW8	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.18502521007586803	[1066]	[1265,823,862,1026]	3	hSpCas9	negative selection	6470888
31156017	31156040	17	-	27260156	EW8	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.2602825044786483	[995]	[696,737,570,707]	-5	hSpCas9	negative selection	6470889
31159045	31159068	17	+	27260156	EW8	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.17408331814279943	[768]	[731,776,560,767]	3	hSpCas9	negative selection	6470890
31163355	31163378	17	+	27260156	CORL105	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.7321403201940897	[958]	[1678,1815,1892,2068]	9	hSpCas9	negative selection	6527881
31159070	31159093	17	+	27260156	CORL105	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.6805280636470943	[649]	[1013,1173,1508,1219]	9	hSpCas9	negative selection	6527882
31163255	31163278	17	+	27260156	CORL105	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.6299128174346247	[601]	[1077,1203,1304,806]	9	hSpCas9	negative selection	6527883
31156021	31156044	17	+	27260156	CORL105	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.7181484437618981	[1066]	[2180,1973,2017,2045]	9	hSpCas9	negative selection	6592139
31156017	31156040	17	-	27260156	CORL105	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.15922597262326765	[995]	[1534,1396,1387,908]	3	hSpCas9	negative selection	6592140
31159045	31159068	17	+	27260156	CORL105	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.4545209458764381	[768]	[1292,1188,1232,1221]	8	hSpCas9	negative selection	6592141
31163355	31163378	17	+	27260156	HS294T	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.4456746604775792	[958]	[408,447,670,500]	6	hSpCas9	negative selection	6649132
31159070	31159093	17	+	27260156	HS294T	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.4121964782096999	[649]	[274,479,239,343]	5	hSpCas9	negative selection	6649133
31163255	31163278	17	+	27260156	HS294T	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.9143018023640439	[601]	[307,468,478,522]	9	hSpCas9	negative selection	6649134
31156021	31156044	17	+	27260156	HS294T	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.479623233082076	[1066]	[835,341,526,576]	6	hSpCas9	negative selection	6713390
31156017	31156040	17	-	27260156	HS294T	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.47607396715088524	[995]	[166,269,285,417]	-6	hSpCas9	negative selection	6713391
31159045	31159068	17	+	27260156	HS294T	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.43765928910587015	[768]	[444,433,343,376]	6	hSpCas9	negative selection	6713392
31163355	31163378	17	+	27260156	HCC44	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.614441500525237	[958]	[1953,1419,2228,1199]	8	hSpCas9	negative selection	6770383
31159070	31159093	17	+	27260156	HCC44	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.2729741769432151	[649]	[782,741,1305,800]	4	hSpCas9	negative selection	6770384
31163255	31163278	17	+	27260156	HCC44	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.3995412542904264	[601]	[732,828,1185,881]	6	hSpCas9	negative selection	6770385
31156021	31156044	17	+	27260156	HCC44	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.11854027053948579	[1066]	[1360,1036,1866,1110]	1	hSpCas9	negative selection	6834641
31156017	31156040	17	-	27260156	HCC44	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.3608096871380281	[995]	[1349,657,700,837]	-5	hSpCas9	negative selection	6834642
31159045	31159068	17	+	27260156	HCC44	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	-0.01875730913695639	[768]	[894,909,832,782]	0	hSpCas9	negative selection	6834643
31163355	31163378	17	+	27260156	G402	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.8069723955684915	[958]	[2434,2038,2274,1513]	8	hSpCas9	negative selection	6891634
31159070	31159093	17	+	27260156	G402	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.7200813796622827	[649]	[1070,2021,1241,912]	8	hSpCas9	negative selection	6891635
31163255	31163278	17	+	27260156	G402	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.4119890095329418	[601]	[815,1360,758,968]	5	hSpCas9	negative selection	6891636
31156021	31156044	17	+	27260156	G402	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.6636219505013998	[1066]	[2301,2688,2011,1344]	7	hSpCas9	negative selection	6955892
31156017	31156040	17	-	27260156	G402	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.4529800006447928	[995]	[1805,1411,1413,2004]	5	hSpCas9	negative selection	6955893
31159045	31159068	17	+	27260156	G402	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.8102399384168981	[768]	[2441,1891,1244,1149]	8	hSpCas9	negative selection	6955894
31163355	31163378	17	+	27260156	L33	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.17385203174987174	[958]	[1037,473,749,941]	4	hSpCas9	negative selection	7012885
31159070	31159093	17	+	27260156	L33	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.37044046430999916	[649]	[851,357,584,705]	7	hSpCas9	negative selection	7012886
31163255	31163278	17	+	27260156	L33	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.6658541999155909	[601]	[1019,385,700,743]	9	hSpCas9	negative selection	7012887
31156021	31156044	17	+	27260156	L33	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.21399444155223235	[1066]	[896,408,538,926]	-5	hSpCas9	negative selection	7077143
31156017	31156040	17	-	27260156	L33	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.4350671605158557	[995]	[784,299,464,688]	-8	hSpCas9	negative selection	7077144
31159045	31159068	17	+	27260156	L33	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.18617611095525777	[768]	[966,341,514,875]	4	hSpCas9	negative selection	7077145
31163355	31163378	17	+	27260156	K562	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.5404943168662304	[958]	[1432,1389,937,1211]	7	hSpCas9	negative selection	7134136
31159070	31159093	17	+	27260156	K562	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.6185713380748004	[649]	[852,948,979,770]	7	hSpCas9	negative selection	7134137
31163255	31163278	17	+	27260156	K562	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.7792559063425377	[601]	[760,1115,1062,741]	8	hSpCas9	negative selection	7134138
31156021	31156044	17	+	27260156	K562	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.07912641311690494	[1066]	[1267,844,759,1122]	1	hSpCas9	negative selection	7198394
31156017	31156040	17	-	27260156	K562	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.4565534131494654	[995]	[502,617,882,565]	-5	hSpCas9	negative selection	7198395
31159045	31159068	17	+	27260156	K562	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.31455254055180526	[768]	[976,755,1137,559]	4	hSpCas9	negative selection	7198396
31163355	31163378	17	+	27260156	HT29	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.4449317466089493	[958]	[1895,1815,1309,1382]	8	hSpCas9	negative selection	7255387
31159070	31159093	17	+	27260156	HT29	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.22648784799181715	[649]	[914,1043,730,1000]	4	hSpCas9	negative selection	7255388
31163255	31163278	17	+	27260156	HT29	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.509971180199279	[601]	[1076,1261,923,932]	8	hSpCas9	negative selection	7255389
31156021	31156044	17	+	27260156	HT29	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.07229405189615101	[1066]	[1232,1473,1361,1373]	1	hSpCas9	negative selection	7319645
31156017	31156040	17	-	27260156	HT29	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.026763026613065843	[995]	[1472,1398,982,958]	0	hSpCas9	negative selection	7319646
31159045	31159068	17	+	27260156	HT29	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.3124928424584952	[768]	[1372,1089,1260,947]	6	hSpCas9	negative selection	7319647
31163355	31163378	17	+	27260156	MHHES1	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.6011503010652754	[958]	[1491,2315,1450,1369]	9	hSpCas9	negative selection	7376638
31159070	31159093	17	+	27260156	MHHES1	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.8859072537488362	[649]	[1378,1677,1309,1106]	9	hSpCas9	negative selection	7376639
31163255	31163278	17	+	27260156	MHHES1	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.765302229777657	[601]	[1121,1316,1226,972]	9	hSpCas9	negative selection	7376640
31156021	31156044	17	+	27260156	MHHES1	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.45976280818347326	[1066]	[2212,1554,1680,1271]	7	hSpCas9	negative selection	7440896
31156017	31156040	17	-	27260156	MHHES1	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.275663075106914	[995]	[1015,1754,1737,981]	5	hSpCas9	negative selection	7440897
31159045	31159068	17	+	27260156	MHHES1	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.722952937626731	[768]	[1697,1439,1409,1219]	9	hSpCas9	negative selection	7440898
31163355	31163378	17	+	27260156	MEWO	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.24645233884848783	[958]	[1129,1167,906]	5	hSpCas9	negative selection	7497889
31159070	31159093	17	+	27260156	MEWO	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.46697466346238686	[649]	[810,781,922]	8	hSpCas9	negative selection	7497890
31163255	31163278	17	+	27260156	MEWO	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.09612270996644323	[601]	[591,593,617]	2	hSpCas9	negative selection	7497891
31156021	31156044	17	+	27260156	MEWO	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.06020034547546804	[1066]	[1346,924,909]	1	hSpCas9	negative selection	7562147
31156017	31156040	17	-	27260156	MEWO	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.0592909199047309	[995]	[1215,694,834]	-1	hSpCas9	negative selection	7562148
31159045	31159068	17	+	27260156	MEWO	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	-0.19436983952264975	[768]	[689,631,575]	-4	hSpCas9	negative selection	7562149
31163355	31163378	17	+	27260156	LNCAPCLONEFGC	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.4440006791976663	[958]	[975,1188,1337,1249]	7	hSpCas9	negative selection	7619140
31159070	31159093	17	+	27260156	LNCAPCLONEFGC	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.31090883688980914	[649]	[695,750,868,624]	5	hSpCas9	negative selection	7619141
31163255	31163278	17	+	27260156	LNCAPCLONEFGC	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.49974793723008604	[601]	[711,874,844,656]	7	hSpCas9	negative selection	7619142
31156021	31156044	17	+	27260156	LNCAPCLONEFGC	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.34135316348965006	[1066]	[1239,1065,1233,1368]	5	hSpCas9	negative selection	7683398
31156017	31156040	17	-	27260156	LNCAPCLONEFGC	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.12723566718918722	[995]	[643,992,918,753]	-2	hSpCas9	negative selection	7683399
31159045	31159068	17	+	27260156	LNCAPCLONEFGC	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.2186767334270936	[768]	[813,692,1129,659]	3	hSpCas9	negative selection	7683400
31163355	31163378	17	+	27260156	PANC0327	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.6170739323812535	[958]	[1223,914,1556,1573]	8	hSpCas9	negative selection	7740391
31159070	31159093	17	+	27260156	PANC0327	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.6585107678179256	[649]	[1292,782,774,841]	8	hSpCas9	negative selection	7740392
31163255	31163278	17	+	27260156	PANC0327	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.6657815878694462	[601]	[1017,671,918,820]	8	hSpCas9	negative selection	7740393
31156021	31156044	17	+	27260156	PANC0327	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.2651821549668145	[1066]	[970,815,774,603]	-4	hSpCas9	negative selection	7804649
31156017	31156040	17	-	27260156	PANC0327	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.03718736945708123	[995]	[703,1322,652,695]	0	hSpCas9	negative selection	7804650
31159045	31159068	17	+	27260156	PANC0327	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	-0.017997736007471787	[768]	[710,449,593,974]	0	hSpCas9	negative selection	7804651
31163355	31163378	17	+	27260156	NCIH2009	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.5586511936204466	[958]	[2254,1904,1813]	7	hSpCas9	negative selection	7861642
31159070	31159093	17	+	27260156	NCIH2009	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.4210176418425002	[649]	[1709,1121,912]	6	hSpCas9	negative selection	7861643
31163255	31163278	17	+	27260156	NCIH2009	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.9774026444591379	[601]	[2284,1303,1506]	9	hSpCas9	negative selection	7861644
31156021	31156044	17	+	27260156	NCIH2009	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.46314066433721734	[1066]	[2313,1940,1959]	6	hSpCas9	negative selection	7925900
31156017	31156040	17	-	27260156	NCIH2009	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.20833608753885646	[995]	[1717,1790,1329]	3	hSpCas9	negative selection	7925901
31159045	31159068	17	+	27260156	NCIH2009	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.5585701835959493	[768]	[1619,1414,1719]	7	hSpCas9	negative selection	7925902
31163355	31163378	17	+	27260156	NCIH1373	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.6174350681463843	[958]	[2213,1106,1535,497]	6	hSpCas9	negative selection	7982893
31159070	31159093	17	+	27260156	NCIH1373	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.8108909806878986	[649]	[1510,1312,1491,206]	7	hSpCas9	negative selection	7982894
31163255	31163278	17	+	27260156	NCIH1373	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	1.4158652031309786	[601]	[2505,1168,1158,682]	9	hSpCas9	negative selection	7982895
31156021	31156044	17	+	27260156	NCIH1373	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.04641258205916343	[1066]	[1288,786,929,451]	0	hSpCas9	negative selection	8047151
31156017	31156040	17	-	27260156	NCIH1373	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.43426497417667	[995]	[615,1052,577,265]	-4	hSpCas9	negative selection	8047152
31159045	31159068	17	+	27260156	NCIH1373	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.6795498436535352	[768]	[1736,1204,690,527]	6	hSpCas9	negative selection	8047153
31163355	31163378	17	+	27260156	PATU8902	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.3173331655000353	[958]	[1593,1136,1380,2731]	3	hSpCas9	negative selection	8104144
31159070	31159093	17	+	27260156	PATU8902	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.6883154659165829	[649]	[1784,1364,868,2019]	7	hSpCas9	negative selection	8104145
31163255	31163278	17	+	27260156	PATU8902	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	1.0531534942592287	[601]	[1974,2230,1450,1309]	9	hSpCas9	negative selection	8104146
31156021	31156044	17	+	27260156	PATU8902	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.2937573853687514	[1066]	[2736,1683,1479,1395]	3	hSpCas9	negative selection	8168402
31156017	31156040	17	-	27260156	PATU8902	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.32231813920061536	[995]	[800,1436,718,1641]	-3	hSpCas9	negative selection	8168403
31159045	31159068	17	+	27260156	PATU8902	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	-0.09739076787566292	[768]	[1187,1015,877,935]	-1	hSpCas9	negative selection	8168404
31163355	31163378	17	+	27260156	PANC1	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.9469027162916996	[958]	[1475,1710,1535,1622]	9	hSpCas9	negative selection	8225395
31159070	31159093	17	+	27260156	PANC1	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.8302096016353557	[649]	[983,1025,1073,893]	9	hSpCas9	negative selection	8225396
31163255	31163278	17	+	27260156	PANC1	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.580573631477418	[601]	[895,1075,501,678]	8	hSpCas9	negative selection	8225397
31156021	31156044	17	+	27260156	PANC1	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	1.2033933525837248	[1066]	[1831,2247,2352,2023]	9	hSpCas9	negative selection	8289653
31156017	31156040	17	-	27260156	PANC1	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.5876883244855129	[995]	[1327,1409,1608,870]	8	hSpCas9	negative selection	8289654
31159045	31159068	17	+	27260156	PANC1	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.3321354366190916	[768]	[629,1156,805,795]	5	hSpCas9	negative selection	8289655
31163355	31163378	17	+	27260156	PANC0813	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.22753615555433138	[958]	[1417,1182,1260,1414]	3	hSpCas9	negative selection	8346646
31159070	31159093	17	+	27260156	PANC0813	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.40715471914342666	[649]	[973,1050,1133,892]	6	hSpCas9	negative selection	8346647
31163255	31163278	17	+	27260156	PANC0813	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.46588394325312765	[601]	[1041,1029,921,919]	7	hSpCas9	negative selection	8346648
31156021	31156044	17	+	27260156	PANC0813	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.3802610247788065	[1066]	[1014,885,1039,916]	-5	hSpCas9	negative selection	8410904
31156017	31156040	17	-	27260156	PANC0813	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.6275304652758842	[995]	[562,812,834,796]	-7	hSpCas9	negative selection	8410905
31159045	31159068	17	+	27260156	PANC0813	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.03204414307269754	[768]	[936,873,920,959]	0	hSpCas9	negative selection	8410906
31163355	31163378	17	+	27260156	RDES	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.5001742500672117	[958]	[1156,1326,1846,2061]	7	hSpCas9	negative selection	8467897
31159070	31159093	17	+	27260156	RDES	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.5233874567303161	[649]	[864,1049,1151,1279]	8	hSpCas9	negative selection	8467898
31163255	31163278	17	+	27260156	RDES	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.6011874953803636	[601]	[781,899,1058,1584]	8	hSpCas9	negative selection	8467899
31156021	31156044	17	+	27260156	RDES	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.7177972961761145	[1066]	[1666,1695,2349,2490]	9	hSpCas9	negative selection	8532155
31156017	31156040	17	-	27260156	RDES	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.34748688414839224	[995]	[1474,1361,1236,1745]	5	hSpCas9	negative selection	8532156
31159045	31159068	17	+	27260156	RDES	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.4469209762810047	[768]	[917,1007,1550,1440]	7	hSpCas9	negative selection	8532157
31163355	31163378	17	+	27260156	PC3	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.42852563461175275	[958]	[700,1124,2369,1539]	8	hSpCas9	negative selection	8589148
31159070	31159093	17	+	27260156	PC3	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.07900077006022382	[649]	[380,632,1254,770]	1	hSpCas9	negative selection	8589149
31163255	31163278	17	+	27260156	PC3	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.3158723068461995	[601]	[486,748,1248,735]	6	hSpCas9	negative selection	8589150
31156021	31156044	17	+	27260156	PC3	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.6459555387248141	[1066]	[1008,1469,3134,1762]	9	hSpCas9	negative selection	8653406
31156017	31156040	17	-	27260156	PC3	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.10831785213257339	[995]	[795,1241,1627,806]	2	hSpCas9	negative selection	8653407
31159045	31159068	17	+	27260156	PC3	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	-0.15501389170586266	[768]	[339,644,1280,825]	-3	hSpCas9	negative selection	8653408
31163355	31163378	17	+	27260156	PATU8988T	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.26175255893489857	[958]	[1302,991,1085,1046]	4	hSpCas9	negative selection	8710399
31159070	31159093	17	+	27260156	PATU8988T	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.24259744761150898	[649]	[780,795,691,705]	4	hSpCas9	negative selection	8710400
31163255	31163278	17	+	27260156	PATU8988T	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.3921013573110794	[601]	[1129,640,671,585]	6	hSpCas9	negative selection	8710401
31156021	31156044	17	+	27260156	PATU8988T	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.11137963800256911	[1066]	[988,1140,829,869]	-2	hSpCas9	negative selection	8774657
31156017	31156040	17	-	27260156	PATU8988T	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.5547113625086435	[995]	[708,437,878,563]	-7	hSpCas9	negative selection	8774658
31159045	31159068	17	+	27260156	PATU8988T	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.25888843248173055	[768]	[748,975,926,913]	4	hSpCas9	negative selection	8774659
31163355	31163378	17	+	27260156	T47D	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.3706342066303401	[958]	[1355,1546,1389,1476]	7	hSpCas9	negative selection	8831650
31159070	31159093	17	+	27260156	T47D	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.1560419232579417	[649]	[873,736,841,933]	3	hSpCas9	negative selection	8831651
31163255	31163278	17	+	27260156	T47D	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.5022873125217239	[601]	[979,876,1011,1117]	9	hSpCas9	negative selection	8831652
31156021	31156044	17	+	27260156	T47D	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.006484130006588318	[1066]	[1386,1117,1152,1305]	0	hSpCas9	negative selection	8895908
31156017	31156040	17	-	27260156	T47D	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.4151350334807138	[995]	[860,772,923,931]	-7	hSpCas9	negative selection	8895909
31159045	31159068	17	+	27260156	T47D	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.15586201493560792	[768]	[910,924,986,1180]	3	hSpCas9	negative selection	8895910
31163355	31163378	17	+	27260156	SU8686	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.39369760238349394	[958]	[1110,865,1223,1967]	6	hSpCas9	negative selection	8952901
31159070	31159093	17	+	27260156	SU8686	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.4590473258000716	[649]	[651,788,989,1198]	7	hSpCas9	negative selection	8952902
31163255	31163278	17	+	27260156	SU8686	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.9244273268241121	[601]	[966,1076,1127,1423]	9	hSpCas9	negative selection	8952903
31156021	31156044	17	+	27260156	SU8686	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.12707127475326296	[1066]	[825,887,1051,1161]	-2	hSpCas9	negative selection	9017159
31156017	31156040	17	-	27260156	SU8686	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.5226434581016329	[995]	[635,645,772,705]	-7	hSpCas9	negative selection	9017160
31159045	31159068	17	+	27260156	SU8686	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.40246870143953983	[768]	[977,803,1156,1139]	6	hSpCas9	negative selection	9017161
31163355	31163378	17	+	27260156	SKES1	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.4686239781672814	[958]	[1799,1246,1121,1187]	8	hSpCas9	negative selection	9074152
31159070	31159093	17	+	27260156	SKES1	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.32365217438567867	[649]	[914,1034,672,673]	6	hSpCas9	negative selection	9074153
31163255	31163278	17	+	27260156	SKES1	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.43892887704027583	[601]	[1273,734,656,656]	8	hSpCas9	negative selection	9074154
31156021	31156044	17	+	27260156	SKES1	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.5068478253148725	[1066]	[1786,1689,1468,1186]	8	hSpCas9	negative selection	9138410
31156017	31156040	17	-	27260156	SKES1	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.1514163381719016	[995]	[1516,1258,896,839]	3	hSpCas9	negative selection	9138411
31159045	31159068	17	+	27260156	SKES1	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.22740783340340975	[768]	[1073,926,754,860]	5	hSpCas9	negative selection	9138412
31163355	31163378	17	+	27260156	TOV112D	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.5090440851360543	[958]	[1151,1870,1463,1091]	8	hSpCas9	negative selection	9195403
31159070	31159093	17	+	27260156	TOV112D	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.20443348235462372	[649]	[842,901,606,693]	4	hSpCas9	negative selection	9195404
31163255	31163278	17	+	27260156	TOV112D	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.38114471912220926	[601]	[940,1085,638,566]	7	hSpCas9	negative selection	9195405
31156021	31156044	17	+	27260156	TOV112D	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.5058056565427784	[1066]	[1299,1597,1304,1855]	8	hSpCas9	negative selection	9259661
31156017	31156040	17	-	27260156	TOV112D	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	0.05154912676521617	[995]	[862,1086,1100,1079]	1	hSpCas9	negative selection	9259662
31159045	31159068	17	+	27260156	TOV112D	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	-0.12256096476791045	[768]	[745,918,511,706]	-2	hSpCas9	negative selection	9259663
31163355	31163378	17	+	27260156	TC71	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.2963739642051202	[958]	[1282,1262,1189,1318]	7	hSpCas9	negative selection	9316654
31159070	31159093	17	+	27260156	TC71	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.08352584424146564	[649]	[647,787,796,718]	2	hSpCas9	negative selection	9316655
31163255	31163278	17	+	27260156	TC71	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.2812385100717666	[601]	[722,669,979,756]	6	hSpCas9	negative selection	9316656
31156021	31156044	17	+	27260156	TC71	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.10156505925049619	[1066]	[1042,1004,1055,1166]	-3	hSpCas9	negative selection	9380912
31156017	31156040	17	-	27260156	TC71	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	-0.3422704468652491	[995]	[780,818,966,795]	-7	hSpCas9	negative selection	9380913
31159045	31159068	17	+	27260156	TC71	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.2654243794381109	[768]	[865,1075,938,1092]	6	hSpCas9	negative selection	9380914
31163355	31163378	17	+	27260156	TC32	viability	TCTTTAGTCGCATTTCTACCAGG	NF1	ENSG00000196712	0.9659667609796887	[958]	[1610,1377,2271,1936]	9	hSpCas9	negative selection	9437905
31159070	31159093	17	+	27260156	TC32	viability	ACACTGGAAAAATGTCTTGCTGG	NF1	ENSG00000196712	0.7654706206835615	[649]	[1103,619,1270,1303]	9	hSpCas9	negative selection	9437906
31163255	31163278	17	+	27260156	TC32	viability	TTTCTTCACACCTGTCGTGAAGG	NF1	ENSG00000196712	0.6809331197652426	[601]	[748,751,1067,1122]	9	hSpCas9	negative selection	9437907
31156021	31156044	17	+	27260156	TC32	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	1.4248172332343374	[1066]	[2787,2482,2784,2613]	9	hSpCas9	negative selection	9502163
31156017	31156040	17	-	27260156	TC32	viability	GTTGTGCTCAGTACTGACTTTGG	NF1	ENSG00000196712	1.0105184299368144	[995]	[1932,1634,2159,1826]	9	hSpCas9	negative selection	9502164
31159045	31159068	17	+	27260156	TC32	viability	TCTCTCTCAGTTGATTATATTGG	NF1	ENSG00000196712	0.6132054252965209	[768]	[922,990,1201,1332]	8	hSpCas9	negative selection	9502165
31095325	31095348	17	-	27869803	HPAFII	viability after 27 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-1.6670519021421084	[312]	[95,14,NaN]	-8	hSpCas9	negative selection	9559915
31156021	31156044	17	+	27869803	HPAFII	viability after 27 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.20992306937423136	[241]	[103,114,NaN]	-1	hSpCas9	negative selection	9559916
31163265	31163288	17	-	27869803	HPAFII	viability after 27 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.05550585159994531	[300]	[260,83,NaN]	0	hSpCas9	negative selection	9559917
31182620	31182643	17	+	27869803	HPAFII	viability after 27 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-1.4487437260199598	[682]	[106,151,NaN]	-7	hSpCas9	negative selection	9559918
31206350	31206373	17	+	27869803	HPAFII	viability after 27 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	-0.1237664256245169	[402]	[80,288,NaN]	-1	hSpCas9	negative selection	9559919
31232842	31232865	17	+	27869803	HPAFII	viability after 27 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.023276106918799444	[797]	[475,384,NaN]	0	hSpCas9	negative selection	9559920
31095325	31095348	17	-	27869803	HPAFII	viability after 15 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.5719882143209372	[312]	[430,98,NaN]	-6	hSpCas9	negative selection	9642364
31156021	31156044	17	+	27869803	HPAFII	viability after 15 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.3133417606927671	[241]	[427,257,NaN]	3	hSpCas9	negative selection	9642365
31163265	31163288	17	-	27869803	HPAFII	viability after 15 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.7314358660279254	[300]	[644,469,NaN]	7	hSpCas9	negative selection	9642366
31182620	31182643	17	+	27869803	HPAFII	viability after 15 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.5542784636751984	[682]	[637,413,NaN]	-5	hSpCas9	negative selection	9642367
31206350	31206373	17	+	27869803	HPAFII	viability after 15 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	-0.23409974541757517	[402]	[284,419,NaN]	-3	hSpCas9	negative selection	9642368
31232842	31232865	17	+	27869803	HPAFII	viability after 15 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.1085556497129967	[797]	[1174,768,NaN]	1	hSpCas9	negative selection	9642369
31095325	31095348	17	-	27869803	ASPC1	viability after 36 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.1155510878582435	[698]	[709,165,26]	1	hSpCas9	negative selection	9724813
31156021	31156044	17	+	27869803	ASPC1	viability after 36 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.7636493078088102	[860]	[755,520,323]	7	hSpCas9	negative selection	9724814
31163265	31163288	17	-	27869803	ASPC1	viability after 36 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.7614935810361941	[998]	[897,290,607]	7	hSpCas9	negative selection	9724815
31182620	31182643	17	+	27869803	ASPC1	viability after 36 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.47902906845455506	[1488]	[1825,231,334]	5	hSpCas9	negative selection	9724816
31206350	31206373	17	+	27869803	ASPC1	viability after 36 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	-0.7190407521168523	[884]	[90,176,261]	-6	hSpCas9	negative selection	9724817
31232842	31232865	17	+	27869803	ASPC1	viability after 36 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.8025996411929328	[2008]	[1811,885,1064]	7	hSpCas9	negative selection	9724818
31095325	31095348	17	-	27869803	PATU8988S	viability after 35 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.420711467199676	[490]	[135,393,NaN]	5	hSpCas9	negative selection	9807262
31156021	31156044	17	+	27869803	PATU8988S	viability after 35 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	1.0926426761856174	[626]	[557,518,NaN]	9	hSpCas9	negative selection	9807263
31163265	31163288	17	-	27869803	PATU8988S	viability after 35 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	-0.5748379520896512	[1018]	[287,262,NaN]	-5	hSpCas9	negative selection	9807264
31182620	31182643	17	+	27869803	PATU8988S	viability after 35 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.7717222196571996	[1274]	[199,401,NaN]	-6	hSpCas9	negative selection	9807265
31206350	31206373	17	+	27869803	PATU8988S	viability after 35 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	-0.9775554906030891	[760]	[220,89,NaN]	-7	hSpCas9	negative selection	9807266
31232842	31232865	17	+	27869803	PATU8988S	viability after 35 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.5887129299132619	[1408]	[821,884,NaN]	6	hSpCas9	negative selection	9807267
31095325	31095348	17	-	27869803	PATU8988S	viability after 31 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.10226489472684278	[490]	[111,271,NaN]	-1	hSpCas9	negative selection	9889711
31156021	31156044	17	+	27869803	PATU8988S	viability after 31 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	1.039018886525199	[626]	[573,436,NaN]	9	hSpCas9	negative selection	9889712
31163265	31163288	17	-	27869803	PATU8988S	viability after 31 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	-0.8058697565275759	[1018]	[143,344,NaN]	-7	hSpCas9	negative selection	9889713
31182620	31182643	17	+	27869803	PATU8988S	viability after 31 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.7518754740137987	[1274]	[216,409,NaN]	-7	hSpCas9	negative selection	9889714
31206350	31206373	17	+	27869803	PATU8988S	viability after 31 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	-0.5368466867432587	[760]	[191,230,NaN]	-5	hSpCas9	negative selection	9889715
31232842	31232865	17	+	27869803	PATU8988S	viability after 31 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	0.5676969166062567	[1408]	[632,1086,NaN]	6	hSpCas9	negative selection	9889716
31095325	31095348	17	-	27869803	HPAFII	viability after 35 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-2.8791480930537263	[312]	[37,2,NaN]	-8	hSpCas9	negative selection	9972160
31156021	31156044	17	+	27869803	HPAFII	viability after 35 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.7365981379300972	[241]	[65,81,NaN]	-4	hSpCas9	negative selection	9972161
31163265	31163288	17	-	27869803	HPAFII	viability after 35 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.6264167672394418	[300]	[349,105,NaN]	4	hSpCas9	negative selection	9972162
31182620	31182643	17	+	27869803	HPAFII	viability after 35 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-1.108165545343704	[682]	[126,197,NaN]	-6	hSpCas9	negative selection	9972163
31206350	31206373	17	+	27869803	HPAFII	viability after 35 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	0.22195878114368328	[402]	[14,488,NaN]	1	hSpCas9	negative selection	9972164
31232842	31232865	17	+	27869803	HPAFII	viability after 35 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	-0.25330090708508135	[797]	[321,357,NaN]	-1	hSpCas9	negative selection	9972165
31095325	31095348	17	-	27869803	HPAFII	viability after 31 days	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-3.028945706607864	[312]	[21,20,NaN]	-8	hSpCas9	negative selection	10054609
31156021	31156044	17	+	27869803	HPAFII	viability after 31 days	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.48568543607214065	[241]	[107,84,NaN]	-3	hSpCas9	negative selection	10054610
31163265	31163288	17	-	27869803	HPAFII	viability after 31 days	ATGCTGGTTTCCTTCACGACAGG	NF1	ENSG00000196712	0.3398695657486839	[300]	[320,96,NaN]	2	hSpCas9	negative selection	10054611
31182620	31182643	17	+	27869803	HPAFII	viability after 31 days	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-1.5664378717548895	[682]	[149,106,NaN]	-7	hSpCas9	negative selection	10054612
31206350	31206373	17	+	27869803	HPAFII	viability after 31 days	CCCAGCAATACGAATGGCACCGG	NF1	ENSG00000196712	0.3079445793246248	[402]	[100,474,NaN]	2	hSpCas9	negative selection	10054613
31232842	31232865	17	+	27869803	HPAFII	viability after 31 days	CTCAATGCCAACGTAGACAGTGG	NF1	ENSG00000196712	-0.6076571253831335	[797]	[302,283,NaN]	-4	hSpCas9	negative selection	10054614
31163310	31163333	17	-	28162770	P31FUJ	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	1.160540223765146	[66]	[175]	9	hSpCas9	negative selection	10199636
31156021	31156044	17	+	28162770	P31FUJ	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.5298032109099268	[144]	[245]	6	hSpCas9	negative selection	10199637
31219014	31219037	17	+	28162770	P31FUJ	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	0.9639985030193287	[64]	[148]	9	hSpCas9	negative selection	10199638
31219094	31219117	17	+	28162770	P31FUJ	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	1.279096834117054	[26]	[76]	9	hSpCas9	negative selection	10199639
31095325	31095348	17	-	28162770	P31FUJ	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.16786900569426266	[327]	[432]	1	hSpCas9	negative selection	10199640
31182620	31182643	17	+	28162770	P31FUJ	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.720200316048452	[77]	[150]	8	hSpCas9	negative selection	10199641
31200446	31200469	17	+	28162770	P31FUJ	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	0.7059709963351751	[360]	[691]	7	hSpCas9	negative selection	10199642
31219000	31219023	17	+	28162770	P31FUJ	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	0.6278987581740724	[200]	[364]	7	hSpCas9	negative selection	10199643
31206344	31206367	17	+	28162770	P31FUJ	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	0.6926508422205675	[138]	[263]	7	hSpCas9	negative selection	10199644
31095348	31095371	17	+	28162770	P31FUJ	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	0.6709824803263184	[247]	[463]	7	hSpCas9	negative selection	10199645
31163310	31163333	17	-	28162770	TF1	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10369002
31156021	31156044	17	+	28162770	TF1	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	NaN	[NaN]	[328]	1	hSpCas9	negative selection	10369003
31219014	31219037	17	+	28162770	TF1	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10369004
31219094	31219117	17	+	28162770	TF1	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10369005
31095325	31095348	17	-	28162770	TF1	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	NaN	[NaN]	[198]	1	hSpCas9	negative selection	10369006
31182620	31182643	17	+	28162770	TF1	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10369007
31200446	31200469	17	+	28162770	TF1	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	NaN	[NaN]	[657]	1	hSpCas9	negative selection	10369008
31219000	31219023	17	+	28162770	TF1	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	NaN	[NaN]	[311]	1	hSpCas9	negative selection	10369009
31206344	31206367	17	+	28162770	TF1	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10369010
31095348	31095371	17	+	28162770	TF1	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	NaN	[NaN]	[746]	1	hSpCas9	negative selection	10369011
31163310	31163333	17	-	28162770	SKM1	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	2.0024267373945404	[23]	[169]	9	hSpCas9	negative selection	10538368
31156021	31156044	17	+	28162770	SKM1	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	2.003557819413189	[44]	[318]	9	hSpCas9	negative selection	10538369
31219014	31219037	17	+	28162770	SKM1	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	0.4093238480844501	[22]	[53]	4	hSpCas9	negative selection	10538370
31219094	31219117	17	+	28162770	SKM1	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	1.499926396865357	[6]	[34]	9	hSpCas9	negative selection	10538371
31095325	31095348	17	-	28162770	SKM1	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	2.734048110783912	[83]	[987]	9	hSpCas9	negative selection	10538372
31182620	31182643	17	+	28162770	SKM1	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.85042364394949	[39]	[254]	9	hSpCas9	negative selection	10538373
31200446	31200469	17	+	28162770	SKM1	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	1.9000356546168158	[101]	[672]	9	hSpCas9	negative selection	10538374
31219000	31219023	17	+	28162770	SKM1	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	1.916766138778186	[39]	[266]	9	hSpCas9	negative selection	10538375
31206344	31206367	17	+	28162770	SKM1	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	0.6068416007818688	[38]	[104]	6	hSpCas9	negative selection	10538376
31095348	31095371	17	+	28162770	SKM1	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	0.5418817133067353	[60]	[156]	5	hSpCas9	negative selection	10538377
31163310	31163333	17	-	28162770	SKM1	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	2.0024267373945404	[23]	[169]	9	hSpCas9	negative selection	10707734
31156021	31156044	17	+	28162770	SKM1	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	2.003557819413189	[44]	[318]	9	hSpCas9	negative selection	10707735
31219014	31219037	17	+	28162770	SKM1	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	0.4093238480844501	[22]	[53]	4	hSpCas9	negative selection	10707736
31219094	31219117	17	+	28162770	SKM1	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	1.499926396865357	[6]	[34]	9	hSpCas9	negative selection	10707737
31095325	31095348	17	-	28162770	SKM1	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	2.734048110783912	[83]	[987]	9	hSpCas9	negative selection	10707738
31182620	31182643	17	+	28162770	SKM1	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.85042364394949	[39]	[254]	9	hSpCas9	negative selection	10707739
31200446	31200469	17	+	28162770	SKM1	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	1.9000356546168158	[101]	[672]	9	hSpCas9	negative selection	10707740
31219000	31219023	17	+	28162770	SKM1	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	1.916766138778186	[39]	[266]	9	hSpCas9	negative selection	10707741
31206344	31206367	17	+	28162770	SKM1	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	0.6068416007818688	[38]	[104]	6	hSpCas9	negative selection	10707742
31095348	31095371	17	+	28162770	SKM1	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	0.5418817133067353	[60]	[156]	5	hSpCas9	negative selection	10707743
31163310	31163333	17	-	28162770	PL21	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	1.6750485697455626	[58]	[81]	9	hSpCas9	negative selection	10877100
31156021	31156044	17	+	28162770	PL21	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.7980411709179743	[110]	[83]	6	hSpCas9	negative selection	10877101
31219014	31219037	17	+	28162770	PL21	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	-0.3382803002948058	[60]	[20]	-2	hSpCas9	negative selection	10877102
31219094	31219117	17	+	28162770	PL21	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	-0.001494246680330491	[22]	[9]	0	hSpCas9	negative selection	10877103
31095325	31095348	17	-	28162770	PL21	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.11106207380498356	[334]	[134]	-1	hSpCas9	negative selection	10877104
31182620	31182643	17	+	28162770	PL21	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-1.7998603855106798	[103]	[12]	-8	hSpCas9	negative selection	10877105
31200446	31200469	17	+	28162770	PL21	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	0.6807654553957408	[343]	[239]	6	hSpCas9	negative selection	10877106
31219000	31219023	17	+	28162770	PL21	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	2.321445910711454	[113]	[247]	9	hSpCas9	negative selection	10877107
31206344	31206367	17	+	28162770	PL21	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	0.6921995339920091	[154]	[108]	6	hSpCas9	negative selection	10877108
31095348	31095371	17	+	28162770	PL21	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	1.2692639751441404	[162]	[170]	9	hSpCas9	negative selection	10877109
31163310	31163333	17	-	28162770	P31FUJ	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	1.160540223765146	[66]	[175]	9	hSpCas9	negative selection	11046466
31156021	31156044	17	+	28162770	P31FUJ	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.5298032109099268	[144]	[245]	6	hSpCas9	negative selection	11046467
31219014	31219037	17	+	28162770	P31FUJ	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	0.9639985030193287	[64]	[148]	9	hSpCas9	negative selection	11046468
31219094	31219117	17	+	28162770	P31FUJ	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	1.279096834117054	[26]	[76]	9	hSpCas9	negative selection	11046469
31095325	31095348	17	-	28162770	P31FUJ	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.16786900569426266	[327]	[432]	1	hSpCas9	negative selection	11046470
31182620	31182643	17	+	28162770	P31FUJ	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.720200316048452	[77]	[150]	8	hSpCas9	negative selection	11046471
31200446	31200469	17	+	28162770	P31FUJ	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	0.7059709963351751	[360]	[691]	7	hSpCas9	negative selection	11046472
31219000	31219023	17	+	28162770	P31FUJ	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	0.6278987581740724	[200]	[364]	7	hSpCas9	negative selection	11046473
31206344	31206367	17	+	28162770	P31FUJ	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	0.6926508422205675	[138]	[263]	7	hSpCas9	negative selection	11046474
31095348	31095371	17	+	28162770	P31FUJ	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	0.6709824803263184	[247]	[463]	7	hSpCas9	negative selection	11046475
31163310	31163333	17	-	28162770	OCIAML5	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	1.2032158646371927	[31]	[132]	8	hSpCas9	negative selection	11215832
31156021	31156044	17	+	28162770	OCIAML5	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	1.3040526310532852	[69]	[311]	9	hSpCas9	negative selection	11215833
31219014	31219037	17	+	28162770	OCIAML5	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	1.0820454934795456	[27]	[106]	8	hSpCas9	negative selection	11215834
31219094	31219117	17	+	28162770	OCIAML5	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	1.7527954872948641	[11]	[72]	9	hSpCas9	negative selection	11215835
31095325	31095348	17	-	28162770	OCIAML5	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.13426838743574854	[196]	[323]	-1	hSpCas9	negative selection	11215836
31182620	31182643	17	+	28162770	OCIAML5	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.7260095442719193	[69]	[208]	6	hSpCas9	negative selection	11215837
31200446	31200469	17	+	28162770	OCIAML5	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	1.40515583463555	[227]	[1089]	9	hSpCas9	negative selection	11215838
31219000	31219023	17	+	28162770	OCIAML5	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	1.0385609004201668	[112]	[418]	8	hSpCas9	negative selection	11215839
31206344	31206367	17	+	28162770	OCIAML5	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	-0.2884777209354079	[135]	[200]	-2	hSpCas9	negative selection	11215840
31095348	31095371	17	+	28162770	OCIAML5	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	1.2872917142824656	[105]	[466]	9	hSpCas9	negative selection	11215841
31163310	31163333	17	-	28162770	EOL1	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	2.3244783784591703	[107]	[284]	9	hSpCas9	negative selection	11385198
31156021	31156044	17	+	28162770	EOL1	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.15739384196564166	[162]	[76]	-1	hSpCas9	negative selection	11385199
31219014	31219037	17	+	28162770	EOL1	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	0.14164589323746957	[116]	[67]	1	hSpCas9	negative selection	11385200
31219094	31219117	17	+	28162770	EOL1	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	1.1958497933879286	[28]	[34]	8	hSpCas9	negative selection	11385201
31095325	31095348	17	-	28162770	EOL1	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.12607830149943355	[608]	[293]	-1	hSpCas9	negative selection	11385202
31182620	31182643	17	+	28162770	EOL1	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	0.09227521730860089	[145]	[81]	0	hSpCas9	negative selection	11385203
31200446	31200469	17	+	28162770	EOL1	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	0.35423204681377984	[489]	[329]	3	hSpCas9	negative selection	11385204
31219000	31219023	17	+	28162770	EOL1	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	-0.21711337765305627	[138]	[62]	-2	hSpCas9	negative selection	11385205
31206344	31206367	17	+	28162770	EOL1	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	0.01531323549371677	[153]	[81]	0	hSpCas9	negative selection	11385206
31095348	31095371	17	+	28162770	EOL1	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	0.7120031361904338	[218]	[188]	6	hSpCas9	negative selection	11385207
31163310	31163333	17	-	28162770	MOLM13	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	0.49891627716520337	[91]	[93]	4	hSpCas9	negative selection	11554564
31156021	31156044	17	+	28162770	MOLM13	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-1.2540740492823808	[286]	[86]	-6	hSpCas9	negative selection	11554565
31219014	31219037	17	+	28162770	MOLM13	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	-1.3565390538719668	[84]	[23]	-6	hSpCas9	negative selection	11554566
31219094	31219117	17	+	28162770	MOLM13	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	0.6658287591564878	[33]	[38]	5	hSpCas9	negative selection	11554567
31095325	31095348	17	-	28162770	MOLM13	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.7442638552870308	[467]	[201]	-4	hSpCas9	negative selection	11554568
31182620	31182643	17	+	28162770	MOLM13	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	-0.7234092706903007	[152]	[66]	-4	hSpCas9	negative selection	11554569
31200446	31200469	17	+	28162770	MOLM13	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	-0.4386660543363574	[537]	[286]	-3	hSpCas9	negative selection	11554570
31219000	31219023	17	+	28162770	MOLM13	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	-1.3734128724363632	[257]	[71]	-6	hSpCas9	negative selection	11554571
31206344	31206367	17	+	28162770	MOLM13	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	-1.0866994701330586	[281]	[95]	-5	hSpCas9	negative selection	11554572
31095348	31095371	17	+	28162770	MOLM13	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	-0.29933042832422035	[256]	[150]	-2	hSpCas9	negative selection	11554573
31163310	31163333	17	-	28162770	HEL	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	2.021250455254087	[89]	[233]	9	hSpCas9	negative selection	11723930
31156021	31156044	17	+	28162770	HEL	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	-0.1663183852882477	[211]	[120]	-1	hSpCas9	negative selection	11723931
31219014	31219037	17	+	28162770	HEL	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	0.6274720753470464	[94]	[93]	5	hSpCas9	negative selection	11723932
31219094	31219117	17	+	28162770	HEL	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	0.592112758930389	[28]	[27]	5	hSpCas9	negative selection	11723933
31095325	31095348	17	-	28162770	HEL	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.13612473036937334	[438]	[308]	1	hSpCas9	negative selection	11723934
31182620	31182643	17	+	28162770	HEL	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.4621665863585362	[101]	[179]	9	hSpCas9	negative selection	11723935
31200446	31200469	17	+	28162770	HEL	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	1.2707700546133993	[373]	[577]	9	hSpCas9	negative selection	11723936
31219000	31219023	17	+	28162770	HEL	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	-0.4999495851681531	[222]	[100]	-3	hSpCas9	negative selection	11723937
31206344	31206367	17	+	28162770	HEL	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	-0.510884357112855	[197]	[88]	-3	hSpCas9	negative selection	11723938
31095348	31095371	17	+	28162770	HEL	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	1.5021405018275564	[209]	[380]	9	hSpCas9	negative selection	11723939
31163310	31163333	17	-	28162770	MV411	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	0.5546190603009513	[58]	[72]	5	hSpCas9	negative selection	11893296
31156021	31156044	17	+	28162770	MV411	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.45653314950576546	[108]	[125]	4	hSpCas9	negative selection	11893297
31219014	31219037	17	+	28162770	MV411	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	-0.8374513468037379	[69]	[32]	-5	hSpCas9	negative selection	11893298
31219094	31219117	17	+	28162770	MV411	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	0.5312305167833666	[22]	[27]	5	hSpCas9	negative selection	11893299
31095325	31095348	17	-	28162770	MV411	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.1336176512256133	[289]	[267]	1	hSpCas9	negative selection	11893300
31182620	31182643	17	+	28162770	MV411	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.2415609844461062	[122]	[244]	9	hSpCas9	negative selection	11893301
31200446	31200469	17	+	28162770	MV411	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	0.5994577108265735	[426]	[544]	5	hSpCas9	negative selection	11893302
31219000	31219023	17	+	28162770	MV411	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	0.9270369256420067	[117]	[188]	8	hSpCas9	negative selection	11893303
31206344	31206367	17	+	28162770	MV411	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	0.35684876750335737	[164]	[177]	3	hSpCas9	negative selection	11893304
31095348	31095371	17	+	28162770	MV411	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	-0.04880390044093752	[166]	[135]	0	hSpCas9	negative selection	11893305
31163310	31163333	17	-	28162770	MONOMAC1	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	0.22565422476272534	[46]	[62]	2	hSpCas9	negative selection	12062662
31156021	31156044	17	+	28162770	MONOMAC1	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.20205910835026855	[90]	[119]	2	hSpCas9	negative selection	12062663
31219014	31219037	17	+	28162770	MONOMAC1	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	2.7571594633273215	[31]	[247]	9	hSpCas9	negative selection	12062664
31219094	31219117	17	+	28162770	MONOMAC1	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	-0.4194292683960019	[13]	[11]	-4	hSpCas9	negative selection	12062665
31095325	31095348	17	-	28162770	MONOMAC1	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	1.5693097704789791	[208]	[710]	9	hSpCas9	negative selection	12062666
31182620	31182643	17	+	28162770	MONOMAC1	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.9184403703603823	[56]	[246]	9	hSpCas9	negative selection	12062667
31200446	31200469	17	+	28162770	MONOMAC1	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	1.8315919835190284	[236]	[966]	9	hSpCas9	negative selection	12062668
31219000	31219023	17	+	28162770	MONOMAC1	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	1.4458065697421023	[56]	[177]	9	hSpCas9	negative selection	12062669
31206344	31206367	17	+	28162770	MONOMAC1	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	0.9743315712524273	[110]	[249]	8	hSpCas9	negative selection	12062670
31095348	31095371	17	+	28162770	MONOMAC1	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	1.1966270014267233	[101]	[267]	9	hSpCas9	negative selection	12062671
31163310	31163333	17	-	28162770	OCIAML2	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	-0.06463746556632444	[9]	[52]	0	hSpCas9	negative selection	12232028
31156021	31156044	17	+	28162770	OCIAML2	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.7540010682902863	[22]	[214]	7	hSpCas9	negative selection	12232029
31219014	31219037	17	+	28162770	OCIAML2	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	0.40383929267398	[8]	[65]	4	hSpCas9	negative selection	12232030
31219094	31219117	17	+	28162770	OCIAML2	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	1.8512982696452012	[1]	[39]	9	hSpCas9	negative selection	12232031
31095325	31095348	17	-	28162770	OCIAML2	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	-0.30351983940690286	[56]	[255]	-2	hSpCas9	negative selection	12232032
31182620	31182643	17	+	28162770	OCIAML2	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.4679696300936955	[8]	[137]	9	hSpCas9	negative selection	12232033
31200446	31200469	17	+	28162770	OCIAML2	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	-0.24156133904989174	[76]	[360]	-2	hSpCas9	negative selection	12232034
31219000	31219023	17	+	28162770	OCIAML2	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	0.6168330160081783	[19]	[169]	6	hSpCas9	negative selection	12232035
31206344	31206367	17	+	28162770	OCIAML2	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	-0.4467830832877935	[29]	[121]	-4	hSpCas9	negative selection	12232036
31095348	31095371	17	+	28162770	OCIAML2	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	0.6992951762001512	[31]	[287]	6	hSpCas9	negative selection	12232037
31163310	31163333	17	-	28162770	OCIAML3	viability	GAGAGAAAATAAAACCCCAGAGG	NF1	ENSG00000196712	1.4165616013860243	[16]	[136]	9	hSpCas9	negative selection	12401394
31156021	31156044	17	+	28162770	OCIAML3	viability	AGTCAGTACTGAGCACAACAAGG	NF1	ENSG00000196712	0.9126264997120334	[40]	[232]	7	hSpCas9	negative selection	12401395
31219014	31219037	17	+	28162770	OCIAML3	viability	AAACAGGGGCCCGAAACCCAAGG	NF1	ENSG00000196712	0.9605812113534743	[15]	[93]	8	hSpCas9	negative selection	12401396
31219094	31219117	17	+	28162770	OCIAML3	viability	AGAGATTGCTCAGGAAGCAATGG	NF1	ENSG00000196712	1.293517630417424	[4]	[36]	9	hSpCas9	negative selection	12401397
31095325	31095348	17	-	28162770	OCIAML3	viability	ACGGCCTGGACCCATTCCACCGG	NF1	ENSG00000196712	0.7914855833406651	[110]	[579]	7	hSpCas9	negative selection	12401398
31182620	31182643	17	+	28162770	OCIAML3	viability	CCAGGATATATCCAAAGACGTGG	NF1	ENSG00000196712	1.360188670062712	[27]	[216]	9	hSpCas9	negative selection	12401399
31200446	31200469	17	+	28162770	OCIAML3	viability	AAAGCTCTTGCTGGCCATGGAGG	NF1	ENSG00000196712	0.9320611713434245	[99]	[575]	7	hSpCas9	negative selection	12401400
31219000	31219023	17	+	28162770	OCIAML3	viability	TGCAGAATCCAAGAAAACAGGGG	NF1	ENSG00000196712	0.5703791775767193	[28]	[129]	5	hSpCas9	negative selection	12401401
31206344	31206367	17	+	28162770	OCIAML3	viability	AGCACACCCAGCAATACGAATGG	NF1	ENSG00000196712	-0.7296627396817295	[38]	[70]	-5	hSpCas9	negative selection	12401402
31095348	31095371	17	+	28162770	OCIAML3	viability	GGTCAGCCGCTTCGACGAGCAGG	NF1	ENSG00000196712	-0.29855175679799184	[65]	[161]	-2	hSpCas9	negative selection	12401403