Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:84033
• Symbol:OBSCN
• Description:obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

DataSource: http://genomecrispr.dkfz.de/#!/results/OBSCN

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
228211912	228211935	1	+	26472758	Jiyoye	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	1.051031571280598	[15]	[24]	7	hSpCas9	negative selection	113189
228287713	228287736	1	+	26472758	Jiyoye	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-5.7013490752722955	[68]	[0]	-9	hSpCas9	negative selection	113190
228213460	228213483	1	+	26472758	Jiyoye	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	-0.30524802839754117	[271]	[165]	-2	hSpCas9	negative selection	113191
228250164	228250187	1	+	26472758	Jiyoye	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	1.3613716918927488	[47]	[92]	7	hSpCas9	negative selection	113192
228256673	228256696	1	+	26472758	Jiyoye	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	0.6751085867525064	[48]	[58]	5	hSpCas9	negative selection	113193
228282099	228282122	1	+	26472758	Jiyoye	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	-0.8629137818618708	[204]	[84]	-6	hSpCas9	negative selection	113194
228211912	228211935	1	+	26472758	KBM7	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	0.2602959119756507	[107,67]	[26,67]	2	hSpCas9	negative selection	304307
228287713	228287736	1	+	26472758	KBM7	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-6.531428637330538	[235,162]	[0,0]	-9	hSpCas9	negative selection	304308
228213460	228213483	1	+	26472758	KBM7	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	-0.1658174015753967	[1075,721]	[473,278]	-2	hSpCas9	negative selection	304309
228250164	228250187	1	+	26472758	KBM7	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	0.7703139526612766	[284,269]	[184,256]	8	hSpCas9	negative selection	304310
228256673	228256696	1	+	26472758	KBM7	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-0.6773832863220756	[308,226]	[78,76]	-5	hSpCas9	negative selection	304311
228282099	228282122	1	+	26472758	KBM7	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	0.28665538957074677	[322,454]	[207,245]	3	hSpCas9	negative selection	304312
228211912	228211935	1	+	26472758	Raji	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	-1.3520480832636976	[43]	[3]	-7	hSpCas9	negative selection	495425
228287713	228287736	1	+	26472758	Raji	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-4.565041806597897	[101]	[0]	-9	hSpCas9	negative selection	495426
228213460	228213483	1	+	26472758	Raji	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	0.21544328123105239	[359]	[96]	2	hSpCas9	negative selection	495427
228250164	228250187	1	+	26472758	Raji	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	-0.4385848337316931	[145]	[24]	-4	hSpCas9	negative selection	495428
228256673	228256696	1	+	26472758	Raji	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-0.6259708052402279	[132]	[19]	-5	hSpCas9	negative selection	495429
228282099	228282122	1	+	26472758	Raji	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	0.4773331451239054	[324]	[104]	4	hSpCas9	negative selection	495430
228211912	228211935	1	+	26472758	K562	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	1.4971847980464137	[46]	[111]	9	hSpCas9	negative selection	686543
228287713	228287736	1	+	26472758	K562	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-6.925506273775865	[143]	[0]	-9	hSpCas9	negative selection	686544
228213460	228213483	1	+	26472758	K562	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	0.05230337069232616	[777]	[680]	0	hSpCas9	negative selection	686545
228250164	228250187	1	+	26472758	K562	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	0.6918777046376682	[230]	[314]	5	hSpCas9	negative selection	686546
228256673	228256696	1	+	26472758	K562	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-1.553678226530061	[232]	[66]	-6	hSpCas9	negative selection	686547
228282099	228282122	1	+	26472758	K562	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	-0.272093986178118	[318]	[222]	-2	hSpCas9	negative selection	686548
228212281	228212304	1	+	26627737	DLD1	viability	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	1.6828239477007592	[62]	[71,98,25]	9	hSpCas9	negative selection	769514
228214187	228214210	1	+	26627737	DLD1	viability	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	-0.2679195342521732	[242]	[79,94,21]	-3	hSpCas9	negative selection	769515
228214820	228214843	1	+	26627737	DLD1	viability	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	0.1871438867820835	[328]	[154,91,104]	2	hSpCas9	negative selection	769516
228215637	228215660	1	+	26627737	DLD1	viability	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	-0.29495817926534373	[250]	[76,106,16]	-3	hSpCas9	negative selection	769517
228216520	228216543	1	+	26627737	DLD1	viability	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-0.2514152762919688	[390]	[69,185,61]	-3	hSpCas9	negative selection	769518
228217155	228217178	1	+	26627737	DLD1	viability	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.2549248928263519	[269]	[98,77,120]	2	hSpCas9	negative selection	769519
228212281	228212304	1	+	26627737	GBM cells	viability after 5 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	-0.3113038325046604	[58]	[12,37]	-5	hSpCas9	negative selection	851829
228214187	228214210	1	+	26627737	GBM cells	viability after 5 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.0026617997235145185	[227]	[79,164]	0	hSpCas9	negative selection	851830
228214820	228214843	1	+	26627737	GBM cells	viability after 5 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-0.28551069625174186	[174]	[74,78]	-4	hSpCas9	negative selection	851831
228215637	228215660	1	+	26627737	GBM cells	viability after 5 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	1.3139513741645295	[26]	[21,49]	9	hSpCas9	negative selection	851832
228216520	228216543	1	+	26627737	GBM cells	viability after 5 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-1.198184813219396	[168]	[28,49]	-9	hSpCas9	negative selection	851833
228217155	228217178	1	+	26627737	GBM cells	viability after 5 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.32421970961835633	[139]	[103,83]	5	hSpCas9	negative selection	851834
228212281	228212304	1	+	26627737	GBM cells	viability after 13 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	-1.0354347162295796	[58]	[8,20]	-8	hSpCas9	negative selection	934144
228214187	228214210	1	+	26627737	GBM cells	viability after 13 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.017625795159399757	[227]	[170,87]	0	hSpCas9	negative selection	934145
228214820	228214843	1	+	26627737	GBM cells	viability after 13 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-0.4292557295987274	[174]	[64,74]	-5	hSpCas9	negative selection	934146
228215637	228215660	1	+	26627737	GBM cells	viability after 13 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	1.6574498094725096	[26]	[59,34]	9	hSpCas9	negative selection	934147
228216520	228216543	1	+	26627737	GBM cells	viability after 13 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-1.9032007649676594	[168]	[18,28]	-9	hSpCas9	negative selection	934148
228217155	228217178	1	+	26627737	GBM cells	viability after 13 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.42087080142099786	[139]	[104,98]	5	hSpCas9	negative selection	934149
228212281	228212304	1	+	26627737	GBM cells	viability after 21 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	-0.34642195240352036	[58]	[31,18]	-3	hSpCas9	negative selection	1016459
228214187	228214210	1	+	26627737	GBM cells	viability after 21 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.26930626935574076	[227]	[165,133]	3	hSpCas9	negative selection	1016460
228214820	228214843	1	+	26627737	GBM cells	viability after 21 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-0.25225927380519797	[174]	[83,75]	-2	hSpCas9	negative selection	1016461
228215637	228215660	1	+	26627737	GBM cells	viability after 21 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	1.210921529158264	[26]	[34,32]	9	hSpCas9	negative selection	1016462
228216520	228216543	1	+	26627737	GBM cells	viability after 21 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-2.528683455731944	[168]	[17,13]	-9	hSpCas9	negative selection	1016463
228217155	228217178	1	+	26627737	GBM cells	viability after 21 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.6494005154785577	[139]	[123,114]	6	hSpCas9	negative selection	1016464
228212281	228212304	1	+	26627737	RPE1	viability after 9 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	6.466013007956107	[1]	[43,69]	9	hSpCas9	negative selection	1098774
228214187	228214210	1	+	26627737	RPE1	viability after 9 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.3800017080682167	[500]	[135,291]	2	hSpCas9	negative selection	1098775
228214820	228214843	1	+	26627737	RPE1	viability after 9 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	0.10242109923450723	[811]	[261,286]	0	hSpCas9	negative selection	1098776
228215637	228215660	1	+	26627737	RPE1	viability after 9 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	-2.5930166497174096	[287]	[17,10]	-9	hSpCas9	negative selection	1098777
228216520	228216543	1	+	26627737	RPE1	viability after 9 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	2.2386123790620176	[195]	[117,510]	9	hSpCas9	negative selection	1098778
228217155	228217178	1	+	26627737	RPE1	viability after 9 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	1.126567794117153	[388]	[247,288]	7	hSpCas9	negative selection	1098779
228212281	228212304	1	+	26627737	RPE1	viability after 12 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	6.095503322056119	[1]	[44,27]	9	hSpCas9	negative selection	1181089
228214187	228214210	1	+	26627737	RPE1	viability after 12 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.4313839053337512	[500]	[215,144]	3	hSpCas9	negative selection	1181090
228214820	228214843	1	+	26627737	RPE1	viability after 12 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	0.05732398177887653	[811]	[260,190]	0	hSpCas9	negative selection	1181091
228215637	228215660	1	+	26627737	RPE1	viability after 12 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	-1.0086339121038237	[287]	[19,57]	-6	hSpCas9	negative selection	1181092
228216520	228216543	1	+	26627737	RPE1	viability after 12 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	2.401528335882091	[195]	[115,449]	9	hSpCas9	negative selection	1181093
228217155	228217178	1	+	26627737	RPE1	viability after 12 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.47409879853969217	[388]	[133,156]	3	hSpCas9	negative selection	1181094
228212281	228212304	1	+	26627737	RPE1	viability after 15 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	7.803813259492632	[1]	[130,121]	9	hSpCas9	negative selection	1263404
228214187	228214210	1	+	26627737	RPE1	viability after 15 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.4347257507626473	[500]	[131,248]	2	hSpCas9	negative selection	1263405
228214820	228214843	1	+	26627737	RPE1	viability after 15 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-0.003072543088718467	[811]	[329,131]	0	hSpCas9	negative selection	1263406
228215637	228215660	1	+	26627737	RPE1	viability after 15 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	-1.4903076891069085	[287]	[0,55]	-7	hSpCas9	negative selection	1263407
228216520	228216543	1	+	26627737	RPE1	viability after 15 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	2.0630349259771297	[195]	[108,349]	8	hSpCas9	negative selection	1263408
228217155	228217178	1	+	26627737	RPE1	viability after 15 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.8018434894873864	[388]	[172,209]	5	hSpCas9	negative selection	1263409
228212281	228212304	1	+	26627737	RPE1	viability after 18 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	7.522473994955267	[1]	[76,122]	9	hSpCas9	negative selection	1345719
228214187	228214210	1	+	26627737	RPE1	viability after 18 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.26935204562613246	[500]	[117,210]	1	hSpCas9	negative selection	1345720
228214820	228214843	1	+	26627737	RPE1	viability after 18 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	0.2603366380588388	[811]	[246,278]	1	hSpCas9	negative selection	1345721
228215637	228215660	1	+	26627737	RPE1	viability after 18 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	-2.1088131134002026	[287]	[3,32]	-8	hSpCas9	negative selection	1345722
228216520	228216543	1	+	26627737	RPE1	viability after 18 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	2.706559988808853	[195]	[192,507]	9	hSpCas9	negative selection	1345723
228217155	228217178	1	+	26627737	RPE1	viability after 18 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.19629033023971365	[388]	[142,95]	1	hSpCas9	negative selection	1345724
228212281	228212304	1	+	26627737	HeLa	viability after 8 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	1.4013482813697729	[44]	[113,4,49]	8	hSpCas9	negative selection	1428034
228214187	228214210	1	+	26627737	HeLa	viability after 8 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	-0.2544240457815085	[467]	[226,103,191]	-2	hSpCas9	negative selection	1428035
228214820	228214843	1	+	26627737	HeLa	viability after 8 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-0.05958976312258002	[315]	[80,58,236]	0	hSpCas9	negative selection	1428036
228215637	228215660	1	+	26627737	HeLa	viability after 8 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	-1.8072692146571616	[60]	[1,18,0]	-9	hSpCas9	negative selection	1428037
228216520	228216543	1	+	26627737	HeLa	viability after 8 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-0.4374986877859194	[330]	[171,17,140]	-4	hSpCas9	negative selection	1428038
228217155	228217178	1	+	26627737	HeLa	viability after 8 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	1.1447458519721778	[166]	[268,181,61]	8	hSpCas9	negative selection	1428039
228212281	228212304	1	+	26627737	HeLa	viability after 12 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	1.8352375772845522	[44]	[147,13,44]	9	hSpCas9	negative selection	1510349
228214187	228214210	1	+	26627737	HeLa	viability after 12 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	-1.0552432632941342	[467]	[120,64,96]	-7	hSpCas9	negative selection	1510350
228214820	228214843	1	+	26627737	HeLa	viability after 12 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-0.13390810505685385	[315]	[55,54,250]	-1	hSpCas9	negative selection	1510351
228215637	228215660	1	+	26627737	HeLa	viability after 12 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	-4.655879210361572	[60]	[0,0,0]	-9	hSpCas9	negative selection	1510352
228216520	228216543	1	+	26627737	HeLa	viability after 12 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-0.7995310074840964	[330]	[52,59,123]	-6	hSpCas9	negative selection	1510353
228217155	228217178	1	+	26627737	HeLa	viability after 12 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.5715230284518047	[166]	[107,119,77]	5	hSpCas9	negative selection	1510354
228212281	228212304	1	+	26627737	HeLa	viability after 15 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	1.342656459025226	[44]	[79,23,33]	8	hSpCas9	negative selection	1592664
228214187	228214210	1	+	26627737	HeLa	viability after 15 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	-0.6898476538155316	[467]	[121,32,205]	-6	hSpCas9	negative selection	1592665
228214820	228214843	1	+	26627737	HeLa	viability after 15 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-0.19885343550853124	[315]	[97,58,184]	-2	hSpCas9	negative selection	1592666
228215637	228215660	1	+	26627737	HeLa	viability after 15 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	-0.6733679801689374	[60]	[0,4,42]	-5	hSpCas9	negative selection	1592667
228216520	228216543	1	+	26627737	HeLa	viability after 15 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-2.105397998269438	[330]	[4,0,92]	-9	hSpCas9	negative selection	1592668
228217155	228217178	1	+	26627737	HeLa	viability after 15 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.8311210221907559	[166]	[198,27,135]	6	hSpCas9	negative selection	1592669
228212281	228212304	1	+	26627737	HeLa	viability after 18 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	1.2198359356113782	[44]	[46,18,33]	8	hSpCas9	negative selection	1674979
228214187	228214210	1	+	26627737	HeLa	viability after 18 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	-0.6743447724896292	[467]	[86,23,205]	-5	hSpCas9	negative selection	1674980
228214820	228214843	1	+	26627737	HeLa	viability after 18 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-0.22582279497613694	[315]	[63,45,184]	-2	hSpCas9	negative selection	1674981
228215637	228215660	1	+	26627737	HeLa	viability after 18 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	-0.6630721822531651	[60]	[0,3,42]	-5	hSpCas9	negative selection	1674982
228216520	228216543	1	+	26627737	HeLa	viability after 18 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-2.063779624590757	[330]	[4,0,92]	-9	hSpCas9	negative selection	1674983
228217155	228217178	1	+	26627737	HeLa	viability after 18 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.7756754560645956	[166]	[123,23,135]	6	hSpCas9	negative selection	1674984
228212281	228212304	1	+	26627737	HCT116	viability after 6 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	-0.941586225642884	[132]	[26,1]	-5	hSpCas9	negative selection	1757294
228214187	228214210	1	+	26627737	HCT116	viability after 6 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.2562023331343307	[534]	[64,119]	1	hSpCas9	negative selection	1757295
228214820	228214843	1	+	26627737	HCT116	viability after 6 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-1.1192909763314631	[482]	[52,24]	-6	hSpCas9	negative selection	1757296
228215637	228215660	1	+	26627737	HCT116	viability after 6 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	0.9301646391865364	[120]	[23,42]	5	hSpCas9	negative selection	1757297
228216520	228216543	1	+	26627737	HCT116	viability after 6 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	0.27914850265521063	[253]	[119,8]	1	hSpCas9	negative selection	1757298
228217155	228217178	1	+	26627737	HCT116	viability after 6 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.13234593144641582	[315]	[18,73]	0	hSpCas9	negative selection	1757299
228212281	228212304	1	+	26627737	HCT116	viability after 8 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	0.655872437564448	[61]	[60,78,21]	6	hSpCas9	negative selection	1839609
228214187	228214210	1	+	26627737	HCT116	viability after 8 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	1.2665299480981438	[140]	[217,212,130]	8	hSpCas9	negative selection	1839610
228214820	228214843	1	+	26627737	HCT116	viability after 8 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	0.950659271321737	[141]	[141,116,193]	8	hSpCas9	negative selection	1839611
228215637	228215660	1	+	26627737	HCT116	viability after 8 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	0.6784768514102426	[72]	[57,68,65]	6	hSpCas9	negative selection	1839612
228216520	228216543	1	+	26627737	HCT116	viability after 8 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-0.6788292405211243	[283]	[151,24,116]	-7	hSpCas9	negative selection	1839613
228217155	228217178	1	+	26627737	HCT116	viability after 8 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.3808339371649192	[184]	[141,92,162]	4	hSpCas9	negative selection	1839614
228212281	228212304	1	+	26627737	HCT116	viability after 9 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	0.025037760316681812	[132]	[10,55]	0	hSpCas9	negative selection	1921924
228214187	228214210	1	+	26627737	HCT116	viability after 9 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	-0.40135318365824924	[534]	[139,82]	-3	hSpCas9	negative selection	1921925
228214820	228214843	1	+	26627737	HCT116	viability after 9 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	0.596840606314458	[482]	[122,251]	4	hSpCas9	negative selection	1921926
228215637	228215660	1	+	26627737	HCT116	viability after 9 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	1.1040387204158641	[120]	[26,102]	7	hSpCas9	negative selection	1921927
228216520	228216543	1	+	26627737	HCT116	viability after 9 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	1.708846295576719	[253]	[171,260]	9	hSpCas9	negative selection	1921928
228217155	228217178	1	+	26627737	HCT116	viability after 9 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.4389932390113913	[315]	[124,105]	3	hSpCas9	negative selection	1921929
228212281	228212304	1	+	26627737	HCT116	viability after 12 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	0.8753893978694518	[61]	[100,30,42]	7	hSpCas9	negative selection	2004239
228214187	228214210	1	+	26627737	HCT116	viability after 12 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.8098801668152016	[140]	[151,180,55]	7	hSpCas9	negative selection	2004240
228214820	228214843	1	+	26627737	HCT116	viability after 12 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	1.4569205621415708	[141]	[232,158,218]	9	hSpCas9	negative selection	2004241
228215637	228215660	1	+	26627737	HCT116	viability after 12 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	1.0133680731715056	[72]	[80,76,73]	8	hSpCas9	negative selection	2004242
228216520	228216543	1	+	26627737	HCT116	viability after 12 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-0.5234188733149445	[283]	[87,107,116]	-5	hSpCas9	negative selection	2004243
228217155	228217178	1	+	26627737	HCT116	viability after 12 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	-0.04218771176549996	[184]	[82,165,36]	0	hSpCas9	negative selection	2004244
228212281	228212304	1	+	26627737	HCT116	viability after 15 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	-0.4646050452168109	[61]	[37,23,16]	-5	hSpCas9	negative selection	2086554
228214187	228214210	1	+	26627737	HCT116	viability after 15 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	1.2054630348707216	[140]	[237,269,59]	8	hSpCas9	negative selection	2086555
228214820	228214843	1	+	26627737	HCT116	viability after 15 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	1.2650190385798168	[141]	[167,90,323]	8	hSpCas9	negative selection	2086556
228215637	228215660	1	+	26627737	HCT116	viability after 15 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	1.0224112020393983	[72]	[77,40,134]	8	hSpCas9	negative selection	2086557
228216520	228216543	1	+	26627737	HCT116	viability after 15 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-0.8963488906733192	[283]	[39,122,93]	-7	hSpCas9	negative selection	2086558
228217155	228217178	1	+	26627737	HCT116	viability after 15 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	-0.507270854231526	[184]	[93,91,40]	-5	hSpCas9	negative selection	2086559
228212281	228212304	1	+	26627737	HCT116	viability after 18 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	-0.2160866756094486	[61]	[73,0,2]	-2	hSpCas9	negative selection	2168869
228214187	228214210	1	+	26627737	HCT116	viability after 18 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.5437137102932205	[140]	[71,179,37]	4	hSpCas9	negative selection	2168870
228214820	228214843	1	+	26627737	HCT116	viability after 18 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	1.6292969769101542	[141]	[174,108,366]	9	hSpCas9	negative selection	2168871
228215637	228215660	1	+	26627737	HCT116	viability after 18 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	0.6420284343409026	[72]	[19,19,130]	5	hSpCas9	negative selection	2168872
228216520	228216543	1	+	26627737	HCT116	viability after 18 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-0.8715008394189814	[283]	[19,192,0]	-7	hSpCas9	negative selection	2168873
228217155	228217178	1	+	26627737	HCT116	viability after 18 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	-0.004704066890895642	[184]	[81,112,69]	0	hSpCas9	negative selection	2168874
228211780	228211803	1	-	24336569	HL60	viability	TGAACTGTGGCTGATCCATGAGG	OBSCN	ENSG00000154358	-0.5758389696192355	[840]	[1193]	-5	hSpCas9	negative selection	2282030
228211785	228211808	1	+	24336569	HL60	viability	TGGATCAGCCACAGTTCAGCGGG	OBSCN	ENSG00000154358	0.28365852892106824	[1348]	[3474]	2	hSpCas9	negative selection	2282031
228211812	228211835	1	-	24336569	HL60	viability	CTTGGGCCGGGTGAGAAAGCGGG	OBSCN	ENSG00000154358	-0.9492602416118179	[718]	[787]	-7	hSpCas9	negative selection	2282032
228211822	228211845	1	+	24336569	HL60	viability	CACCCGGCCCAAGGCCTTCGTGG	OBSCN	ENSG00000154358	0.41449339403351476	[506]	[1429]	4	hSpCas9	negative selection	2282033
228211828	228211851	1	+	24336569	HL60	viability	GCCCAAGGCCTTCGTGGTGTCGG	OBSCN	ENSG00000154358	0.3403625643125865	[900]	[2413]	3	hSpCas9	negative selection	2282034
228211836	228211859	1	-	24336569	HL60	viability	CTTGCCCACCGACACCACGAAGG	OBSCN	ENSG00000154358	0.002725986074063158	[1297]	[2751]	0	hSpCas9	negative selection	2282035
228211863	228211886	1	-	24336569	HL60	viability	CACGATCTGGCAGCTGAGGGTGG	OBSCN	ENSG00000154358	-0.09225738070289902	[804]	[1597]	-1	hSpCas9	negative selection	2282036
228211876	228211899	1	-	24336569	HL60	viability	GCGTGGGATTACCCACGATCTGG	OBSCN	ENSG00000154358	1.4903793924976367	[312]	[1860]	8	hSpCas9	negative selection	2282037
228211882	228211905	1	+	24336569	HL60	viability	CGTGGGTAATCCCACGCCACAGG	OBSCN	ENSG00000154358	2.9185358993711032	[0]	[15]	9	hSpCas9	negative selection	2282038
228211890	228211913	1	+	24336569	HL60	viability	ATCCCACGCCACAGGTGAGCTGG	OBSCN	ENSG00000154358	0.9276196190866428	[1226]	[4938]	7	hSpCas9	negative selection	2282039
228211780	228211803	1	-	24336569	KBM7	viability	TGAACTGTGGCTGATCCATGAGG	OBSCN	ENSG00000154358	0.7114610604808754	[679]	[3036]	6	hSpCas9	negative selection	2349207
228211785	228211808	1	+	24336569	KBM7	viability	TGGATCAGCCACAGTTCAGCGGG	OBSCN	ENSG00000154358	0.5520080742133178	[873]	[3494]	5	hSpCas9	negative selection	2349208
228211812	228211835	1	-	24336569	KBM7	viability	CTTGGGCCGGGTGAGAAAGCGGG	OBSCN	ENSG00000154358	0.21011780827205825	[360]	[1138]	2	hSpCas9	negative selection	2349209
228211822	228211845	1	+	24336569	KBM7	viability	CACCCGGCCCAAGGCCTTCGTGG	OBSCN	ENSG00000154358	0.4974393796812515	[467]	[1801]	4	hSpCas9	negative selection	2349210
228211828	228211851	1	+	24336569	KBM7	viability	GCCCAAGGCCTTCGTGGTGTCGG	OBSCN	ENSG00000154358	0.40223519702520694	[616]	[2223]	4	hSpCas9	negative selection	2349211
228211836	228211859	1	-	24336569	KBM7	viability	CTTGCCCACCGACACCACGAAGG	OBSCN	ENSG00000154358	-0.5511040325971042	[1176]	[2190]	-4	hSpCas9	negative selection	2349212
228211863	228211886	1	-	24336569	KBM7	viability	CACGATCTGGCAGCTGAGGGTGG	OBSCN	ENSG00000154358	-0.41027303027070205	[877]	[1801]	-3	hSpCas9	negative selection	2349213
228211876	228211899	1	-	24336569	KBM7	viability	GCGTGGGATTACCCACGATCTGG	OBSCN	ENSG00000154358	1.0097691075879256	[251]	[1383]	8	hSpCas9	negative selection	2349214
228211882	228211905	1	+	24336569	KBM7	viability	CGTGGGTAATCCCACGCCACAGG	OBSCN	ENSG00000154358	-1.1327058591954704	[40]	[50]	-7	hSpCas9	negative selection	2349215
228211890	228211913	1	+	24336569	KBM7	viability	ATCCCACGCCACAGGTGAGCTGG	OBSCN	ENSG00000154358	1.1943437050907897	[686]	[4287]	8	hSpCas9	negative selection	2349216
228211836	228211859	1	-	27260157	DLD1	viability	CTTGCCCACCGACACCACGAAGG	OBSCN	ENSG00000154358	0.744140826216562	[]	[]	8	hSpCas9	negative selection	2579241
228212029	228212052	1	-	27260157	DLD1	viability	CGCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	-1.06339832566221	[]	[]	-7	hSpCas9	negative selection	2581181
228211780	228211803	1	-	27260157	DLD1	viability	TGAACTGTGGCTGATCCATGAGG	OBSCN	ENSG00000154358	0.305330206937264	[]	[]	4	hSpCas9	negative selection	2582261
228211994	228212017	1	+	27260157	DLD1	viability	GACCTGGCGCTGGGCGACAGTGG	OBSCN	ENSG00000154358	0.253306480550709	[]	[]	4	hSpCas9	negative selection	2582502
228212027	228212050	1	+	27260157	DLD1	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-0.822291411478956	[]	[]	-6	hSpCas9	negative selection	2587704
228211972	228211995	1	-	27260157	DLD1	viability	CCAGGATAGTGAGGCGGTAGAGG	OBSCN	ENSG00000154358	0.311635701306591	[]	[]	4	hSpCas9	negative selection	2607065
228211822	228211845	1	+	27260157	DLD1	viability	CACCCGGCCCAAGGCCTTCGTGG	OBSCN	ENSG00000154358	0.51085895759148	[]	[]	8	hSpCas9	negative selection	2607896
228212162	228212185	1	+	27260157	DLD1	viability	GCCACCTTCCGCTGCCGCGTGGG	OBSCN	ENSG00000154358	-0.633957537006854	[]	[]	-5	hSpCas9	negative selection	2610546
228211828	228211851	1	+	27260157	DLD1	viability	GCCCAAGGCCTTCGTGGTGTCGG	OBSCN	ENSG00000154358	1.4008041304474	[]	[]	9	hSpCas9	negative selection	2611996
228211882	228211905	1	+	27260157	DLD1	viability	CGTGGGTAATCCCACGCCACAGG	OBSCN	ENSG00000154358	0.764858084875534	[]	[]	8	hSpCas9	negative selection	2614185
228211785	228211808	1	+	27260157	DLD1	viability	TGGATCAGCCACAGTTCAGCGGG	OBSCN	ENSG00000154358	-0.488250632128772	[]	[]	-4	hSpCas9	negative selection	2614668
228211769	228211792	1	-	27260157	DLD1	viability	TGATCCATGAGGGTGGCGGCGGG	OBSCN	ENSG00000154358	0.0380374875255465	[]	[]	0	hSpCas9	negative selection	2614966
228212131	228212154	1	+	27260157	DLD1	viability	CACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.878696303782192	[]	[]	9	hSpCas9	negative selection	2621949
228211863	228211886	1	-	27260157	DLD1	viability	CACGATCTGGCAGCTGAGGGTGG	OBSCN	ENSG00000154358	0.743796008375379	[]	[]	8	hSpCas9	negative selection	2623485
228211812	228211835	1	-	27260157	DLD1	viability	CTTGGGCCGGGTGAGAAAGCGGG	OBSCN	ENSG00000154358	-0.846038805133825	[]	[]	-6	hSpCas9	negative selection	2623988
228212129	228212152	1	-	27260157	DLD1	viability	TCGCGCACGCGGATGGACGTGGG	OBSCN	ENSG00000154358	0.218480289118904	[]	[]	3	hSpCas9	negative selection	2642458
228211890	228211913	1	+	27260157	DLD1	viability	ATCCCACGCCACAGGTGAGCTGG	OBSCN	ENSG00000154358	0.210489604774186	[]	[]	3	hSpCas9	negative selection	2643963
228212140	228212163	1	-	27260157	DLD1	viability	CCTCTGAGCCCTCGCGCACGCGG	OBSCN	ENSG00000154358	-0.373419140317873	[]	[]	-3	hSpCas9	negative selection	2644688
228211813	228211836	1	+	27260157	DLD1	viability	CCGCTTTCTCACCCGGCCCAAGG	OBSCN	ENSG00000154358	-0.137471122590803	[]	[]	-1	hSpCas9	negative selection	2645620
228211836	228211859	1	-	27260157	HT1080	viability	CTTGCCCACCGACACCACGAAGG	OBSCN	ENSG00000154358	0.913721829897717	[]	[]	7	hSpCas9	negative selection	2655371
228212029	228212052	1	-	27260157	HT1080	viability	CGCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	-0.293161870909215	[]	[]	-7	hSpCas9	negative selection	2657311
228211780	228211803	1	-	27260157	HT1080	viability	TGAACTGTGGCTGATCCATGAGG	OBSCN	ENSG00000154358	0.350302877312283	[]	[]	3	hSpCas9	negative selection	2658391
228211994	228212017	1	+	27260157	HT1080	viability	GACCTGGCGCTGGGCGACAGTGG	OBSCN	ENSG00000154358	0.0898069242976155	[]	[]	1	hSpCas9	negative selection	2658632
228212027	228212050	1	+	27260157	HT1080	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-2.51385070943029	[]	[]	-9	hSpCas9	negative selection	2663834
228211972	228211995	1	-	27260157	HT1080	viability	CCAGGATAGTGAGGCGGTAGAGG	OBSCN	ENSG00000154358	0.392635285667787	[]	[]	3	hSpCas9	negative selection	2683195
228211822	228211845	1	+	27260157	HT1080	viability	CACCCGGCCCAAGGCCTTCGTGG	OBSCN	ENSG00000154358	0.178084192434731	[]	[]	1	hSpCas9	negative selection	2684026
228212162	228212185	1	+	27260157	HT1080	viability	GCCACCTTCCGCTGCCGCGTGGG	OBSCN	ENSG00000154358	-0.194047048364077	[]	[]	0	hSpCas9	negative selection	2686676
228211828	228211851	1	+	27260157	HT1080	viability	GCCCAAGGCCTTCGTGGTGTCGG	OBSCN	ENSG00000154358	0.261889938333826	[]	[]	2	hSpCas9	negative selection	2688126
228211882	228211905	1	+	27260157	HT1080	viability	CGTGGGTAATCCCACGCCACAGG	OBSCN	ENSG00000154358	-0.874366082700731	[]	[]	-8	hSpCas9	negative selection	2690315
228211785	228211808	1	+	27260157	HT1080	viability	TGGATCAGCCACAGTTCAGCGGG	OBSCN	ENSG00000154358	0.75137187914612	[]	[]	6	hSpCas9	negative selection	2690798
228211769	228211792	1	-	27260157	HT1080	viability	TGATCCATGAGGGTGGCGGCGGG	OBSCN	ENSG00000154358	-0.0749150745860567	[]	[]	0	hSpCas9	negative selection	2691096
228212131	228212154	1	+	27260157	HT1080	viability	CACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	-0.08982416990937481	[]	[]	0	hSpCas9	negative selection	2698079
228211863	228211886	1	-	27260157	HT1080	viability	CACGATCTGGCAGCTGAGGGTGG	OBSCN	ENSG00000154358	0.334925348377774	[]	[]	3	hSpCas9	negative selection	2699615
228211812	228211835	1	-	27260157	HT1080	viability	CTTGGGCCGGGTGAGAAAGCGGG	OBSCN	ENSG00000154358	-1.66661576423974	[]	[]	-9	hSpCas9	negative selection	2700118
228212129	228212152	1	-	27260157	HT1080	viability	TCGCGCACGCGGATGGACGTGGG	OBSCN	ENSG00000154358	0.294403899402765	[]	[]	2	hSpCas9	negative selection	2718588
228211890	228211913	1	+	27260157	HT1080	viability	ATCCCACGCCACAGGTGAGCTGG	OBSCN	ENSG00000154358	0.169617339604124	[]	[]	1	hSpCas9	negative selection	2720093
228212140	228212163	1	-	27260157	HT1080	viability	CCTCTGAGCCCTCGCGCACGCGG	OBSCN	ENSG00000154358	-0.364918843394343	[]	[]	-7	hSpCas9	negative selection	2720818
228211813	228211836	1	+	27260157	HT1080	viability	CCGCTTTCTCACCCGGCCCAAGG	OBSCN	ENSG00000154358	-0.445080920340456	[]	[]	-7	hSpCas9	negative selection	2721750
228211836	228211859	1	-	27260157	MKN45	viability	CTTGCCCACCGACACCACGAAGG	OBSCN	ENSG00000154358	-0.426560870452794	[]	[]	-6	hSpCas9	negative selection	2731501
228212029	228212052	1	-	27260157	MKN45	viability	CGCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	-0.808552122640879	[]	[]	-7	hSpCas9	negative selection	2733441
228211780	228211803	1	-	27260157	MKN45	viability	TGAACTGTGGCTGATCCATGAGG	OBSCN	ENSG00000154358	0.489818930300217	[]	[]	6	hSpCas9	negative selection	2734521
228211994	228212017	1	+	27260157	MKN45	viability	GACCTGGCGCTGGGCGACAGTGG	OBSCN	ENSG00000154358	-0.310663891829653	[]	[]	-1	hSpCas9	negative selection	2734762
228212027	228212050	1	+	27260157	MKN45	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-1.51259711594118	[]	[]	-8	hSpCas9	negative selection	2739964
228211972	228211995	1	-	27260157	MKN45	viability	CCAGGATAGTGAGGCGGTAGAGG	OBSCN	ENSG00000154358	-0.131380299605033	[]	[]	0	hSpCas9	negative selection	2759325
228211822	228211845	1	+	27260157	MKN45	viability	CACCCGGCCCAAGGCCTTCGTGG	OBSCN	ENSG00000154358	0.223008455097362	[]	[]	5	hSpCas9	negative selection	2760156
228212162	228212185	1	+	27260157	MKN45	viability	GCCACCTTCCGCTGCCGCGTGGG	OBSCN	ENSG00000154358	-0.557654015914603	[]	[]	-6	hSpCas9	negative selection	2762806
228211828	228211851	1	+	27260157	MKN45	viability	GCCCAAGGCCTTCGTGGTGTCGG	OBSCN	ENSG00000154358	-0.350987972136803	[]	[]	-1	hSpCas9	negative selection	2764256
228211882	228211905	1	+	27260157	MKN45	viability	CGTGGGTAATCCCACGCCACAGG	OBSCN	ENSG00000154358	-0.50611106415526	[]	[]	-6	hSpCas9	negative selection	2766445
228211785	228211808	1	+	27260157	MKN45	viability	TGGATCAGCCACAGTTCAGCGGG	OBSCN	ENSG00000154358	0.526846216677077	[]	[]	6	hSpCas9	negative selection	2766928
228211769	228211792	1	-	27260157	MKN45	viability	TGATCCATGAGGGTGGCGGCGGG	OBSCN	ENSG00000154358	0.102657937657424	[]	[]	0	hSpCas9	negative selection	2767226
228212131	228212154	1	+	27260157	MKN45	viability	CACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.346508314282126	[]	[]	6	hSpCas9	negative selection	2774209
228211863	228211886	1	-	27260157	MKN45	viability	CACGATCTGGCAGCTGAGGGTGG	OBSCN	ENSG00000154358	0.908097291814904	[]	[]	8	hSpCas9	negative selection	2775745
228211812	228211835	1	-	27260157	MKN45	viability	CTTGGGCCGGGTGAGAAAGCGGG	OBSCN	ENSG00000154358	-0.587771767532132	[]	[]	-6	hSpCas9	negative selection	2776248
228212129	228212152	1	-	27260157	MKN45	viability	TCGCGCACGCGGATGGACGTGGG	OBSCN	ENSG00000154358	0.417947135224486	[]	[]	6	hSpCas9	negative selection	2794718
228211890	228211913	1	+	27260157	MKN45	viability	ATCCCACGCCACAGGTGAGCTGG	OBSCN	ENSG00000154358	0.314253993598797	[]	[]	5	hSpCas9	negative selection	2796223
228212140	228212163	1	-	27260157	MKN45	viability	CCTCTGAGCCCTCGCGCACGCGG	OBSCN	ENSG00000154358	-0.0257587460836723	[]	[]	0	hSpCas9	negative selection	2796948
228211813	228211836	1	+	27260157	MKN45	viability	CCGCTTTCTCACCCGGCCCAAGG	OBSCN	ENSG00000154358	-0.487073377549536	[]	[]	-6	hSpCas9	negative selection	2797880
228211836	228211859	1	-	27260157	RKO	viability	CTTGCCCACCGACACCACGAAGG	OBSCN	ENSG00000154358	0.6341796715926	[]	[]	3	hSpCas9	negative selection	2807631
228212029	228212052	1	-	27260157	RKO	viability	CGCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	-0.00445034571454454	[]	[]	0	hSpCas9	negative selection	2809571
228211780	228211803	1	-	27260157	RKO	viability	TGAACTGTGGCTGATCCATGAGG	OBSCN	ENSG00000154358	0.401146280145709	[]	[]	2	hSpCas9	negative selection	2810651
228211994	228212017	1	+	27260157	RKO	viability	GACCTGGCGCTGGGCGACAGTGG	OBSCN	ENSG00000154358	0.701035976626629	[]	[]	8	hSpCas9	negative selection	2810892
228212027	228212050	1	+	27260157	RKO	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-1.60759989854708	[]	[]	-9	hSpCas9	negative selection	2816094
228211972	228211995	1	-	27260157	RKO	viability	CCAGGATAGTGAGGCGGTAGAGG	OBSCN	ENSG00000154358	0.22163586479623	[]	[]	1	hSpCas9	negative selection	2835455
228211822	228211845	1	+	27260157	RKO	viability	CACCCGGCCCAAGGCCTTCGTGG	OBSCN	ENSG00000154358	0.276936823872028	[]	[]	1	hSpCas9	negative selection	2836286
228212162	228212185	1	+	27260157	RKO	viability	GCCACCTTCCGCTGCCGCGTGGG	OBSCN	ENSG00000154358	-0.158850768921719	[]	[]	-1	hSpCas9	negative selection	2838936
228211828	228211851	1	+	27260157	RKO	viability	GCCCAAGGCCTTCGTGGTGTCGG	OBSCN	ENSG00000154358	0.788876306634172	[]	[]	8	hSpCas9	negative selection	2840386
228211882	228211905	1	+	27260157	RKO	viability	CGTGGGTAATCCCACGCCACAGG	OBSCN	ENSG00000154358	-0.324936904523843	[]	[]	-6	hSpCas9	negative selection	2842575
228211785	228211808	1	+	27260157	RKO	viability	TGGATCAGCCACAGTTCAGCGGG	OBSCN	ENSG00000154358	-0.504388562473687	[]	[]	-6	hSpCas9	negative selection	2843058
228211769	228211792	1	-	27260157	RKO	viability	TGATCCATGAGGGTGGCGGCGGG	OBSCN	ENSG00000154358	0.428685046025938	[]	[]	2	hSpCas9	negative selection	2843356
228212131	228212154	1	+	27260157	RKO	viability	CACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.957066136052179	[]	[]	8	hSpCas9	negative selection	2850339
228211863	228211886	1	-	27260157	RKO	viability	CACGATCTGGCAGCTGAGGGTGG	OBSCN	ENSG00000154358	0.293979976068742	[]	[]	1	hSpCas9	negative selection	2851875
228211812	228211835	1	-	27260157	RKO	viability	CTTGGGCCGGGTGAGAAAGCGGG	OBSCN	ENSG00000154358	-0.819439926950137	[]	[]	-7	hSpCas9	negative selection	2852378
228212129	228212152	1	-	27260157	RKO	viability	TCGCGCACGCGGATGGACGTGGG	OBSCN	ENSG00000154358	0.469042808753195	[]	[]	2	hSpCas9	negative selection	2870848
228211890	228211913	1	+	27260157	RKO	viability	ATCCCACGCCACAGGTGAGCTGG	OBSCN	ENSG00000154358	1.39635429888507	[]	[]	9	hSpCas9	negative selection	2872353
228212140	228212163	1	-	27260157	RKO	viability	CCTCTGAGCCCTCGCGCACGCGG	OBSCN	ENSG00000154358	-0.116631203837698	[]	[]	0	hSpCas9	negative selection	2873078
228211813	228211836	1	+	27260157	RKO	viability	CCGCTTTCTCACCCGGCCCAAGG	OBSCN	ENSG00000154358	-0.895149434155253	[]	[]	-8	hSpCas9	negative selection	2874010
228211836	228211859	1	-	27260157	SF268	viability	CTTGCCCACCGACACCACGAAGG	OBSCN	ENSG00000154358	1.05777960213896	[]	[]	9	hSpCas9	negative selection	2883761
228212029	228212052	1	-	27260157	SF268	viability	CGCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	0.15002741602328	[]	[]	0	hSpCas9	negative selection	2885701
228211780	228211803	1	-	27260157	SF268	viability	TGAACTGTGGCTGATCCATGAGG	OBSCN	ENSG00000154358	0.165761754918357	[]	[]	0	hSpCas9	negative selection	2886781
228211994	228212017	1	+	27260157	SF268	viability	GACCTGGCGCTGGGCGACAGTGG	OBSCN	ENSG00000154358	-0.232377620144284	[]	[]	-2	hSpCas9	negative selection	2887022
228212027	228212050	1	+	27260157	SF268	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-1.21853128372349	[]	[]	-7	hSpCas9	negative selection	2892224
228211972	228211995	1	-	27260157	SF268	viability	CCAGGATAGTGAGGCGGTAGAGG	OBSCN	ENSG00000154358	-0.833460269737267	[]	[]	-6	hSpCas9	negative selection	2911585
228211822	228211845	1	+	27260157	SF268	viability	CACCCGGCCCAAGGCCTTCGTGG	OBSCN	ENSG00000154358	0.496245169629431	[]	[]	7	hSpCas9	negative selection	2912416
228212162	228212185	1	+	27260157	SF268	viability	GCCACCTTCCGCTGCCGCGTGGG	OBSCN	ENSG00000154358	0.296183721940963	[]	[]	4	hSpCas9	negative selection	2915066
228211828	228211851	1	+	27260157	SF268	viability	GCCCAAGGCCTTCGTGGTGTCGG	OBSCN	ENSG00000154358	0.390078294582614	[]	[]	4	hSpCas9	negative selection	2916516
228211882	228211905	1	+	27260157	SF268	viability	CGTGGGTAATCCCACGCCACAGG	OBSCN	ENSG00000154358	0.532617480333054	[]	[]	8	hSpCas9	negative selection	2918705
228211785	228211808	1	+	27260157	SF268	viability	TGGATCAGCCACAGTTCAGCGGG	OBSCN	ENSG00000154358	0.40880008550311	[]	[]	4	hSpCas9	negative selection	2919188
228211769	228211792	1	-	27260157	SF268	viability	TGATCCATGAGGGTGGCGGCGGG	OBSCN	ENSG00000154358	-0.504208481321648	[]	[]	-4	hSpCas9	negative selection	2919486
228212131	228212154	1	+	27260157	SF268	viability	CACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	1.14787466244877	[]	[]	9	hSpCas9	negative selection	2926469
228211863	228211886	1	-	27260157	SF268	viability	CACGATCTGGCAGCTGAGGGTGG	OBSCN	ENSG00000154358	0.684586995186119	[]	[]	8	hSpCas9	negative selection	2928005
228211812	228211835	1	-	27260157	SF268	viability	CTTGGGCCGGGTGAGAAAGCGGG	OBSCN	ENSG00000154358	-0.646972827923383	[]	[]	-5	hSpCas9	negative selection	2928508
228212129	228212152	1	-	27260157	SF268	viability	TCGCGCACGCGGATGGACGTGGG	OBSCN	ENSG00000154358	0.544767375133652	[]	[]	8	hSpCas9	negative selection	2946978
228211890	228211913	1	+	27260157	SF268	viability	ATCCCACGCCACAGGTGAGCTGG	OBSCN	ENSG00000154358	0.400606652442624	[]	[]	4	hSpCas9	negative selection	2948483
228212140	228212163	1	-	27260157	SF268	viability	CCTCTGAGCCCTCGCGCACGCGG	OBSCN	ENSG00000154358	0.132497890521637	[]	[]	0	hSpCas9	negative selection	2949208
228211813	228211836	1	+	27260157	SF268	viability	CCGCTTTCTCACCCGGCCCAAGG	OBSCN	ENSG00000154358	-1.01379561139029	[]	[]	-7	hSpCas9	negative selection	2950140
228246787	228246810	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGACCTGAAACATCCAGGTGG	OBSCN	ENSG00000154358	0.4642553062278036	[4,3]	[3,5]	8	hSpCas9	positive selection	3007195
228278728	228278751	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTGCCATGGAGAAGCACCGCGG	OBSCN	ENSG00000154358	-0.2478708454933348	[4,4]	[4,2]	-4	hSpCas9	positive selection	3007196
228278744	228278767	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGACACTCCAGCACACCGCGG	OBSCN	ENSG00000154358	0.033184234094537024	[5,5]	[4,4]	0	hSpCas9	positive selection	3007197
228215730	228215753	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACACGCTCACCATCCGGGAGG	OBSCN	ENSG00000154358	0.021006399277846144	[4,4]	[3,3]	0	hSpCas9	positive selection	3007198
228246787	228246810	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGACCTGAAACATCCAGGTGG	OBSCN	ENSG00000154358	-0.28734347289464157	[4,4]	[4,0]	-4	hSpCas9	positive selection	3075053
228278728	228278751	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTGCCATGGAGAAGCACCGCGG	OBSCN	ENSG00000154358	0.13749662344324498	[4,4]	[3,2]	2	hSpCas9	positive selection	3075054
228278744	228278767	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGACACTCCAGCACACCGCGG	OBSCN	ENSG00000154358	0.22970294890174336	[5,5]	[5,3]	4	hSpCas9	positive selection	3075055
228215730	228215753	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACACGCTCACCATCCGGGAGG	OBSCN	ENSG00000154358	-0.09444570609647712	[4,4]	[4,1]	-1	hSpCas9	positive selection	3075056
228214194	228214217		-	24336571	A375	resistance to PLX after 7 days	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	-0.2536728893460849	[44,43]	[35,37]	-7	hSpCas9	positive selection	3132254
228214418	228214441		-	24336571	A375	resistance to PLX after 7 days	CCTCACCCGACACGCAGAACTGG	OBSCN	ENSG00000154358	0.0491586644153027	[23,19]	[25,18]	1	hSpCas9	positive selection	3132255
228214307	228214330		-	24336571	A375	resistance to PLX after 7 days	CCTCCGCGGAGATGGCCACGCGG	OBSCN	ENSG00000154358	-0.24771911241668176	[30,32]	[28,24]	-7	hSpCas9	positive selection	3132256
228212309	228212332		-	24336571	A375	resistance to PLX after 7 days	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	-0.053827730642486804	[29,26]	[27,25]	-1	hSpCas9	positive selection	3132257
228212027	228212050		+	24336571	A375	resistance to PLX after 7 days	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.2506706885176837	[50,44]	[61,51]	7	hSpCas9	positive selection	3132258
228214194	228214217		-	24336571	A375	resistance to PLX after 14 days	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.033584365867590726	[39,45]	[19,20]	0	hSpCas9	positive selection	3190047
228214418	228214441		-	24336571	A375	resistance to PLX after 14 days	CCTCACCCGACACGCAGAACTGG	OBSCN	ENSG00000154358	0.39525017750409996	[25,14]	[11,12]	4	hSpCas9	positive selection	3190048
228214307	228214330		-	24336571	A375	resistance to PLX after 14 days	CCTCCGCGGAGATGGCCACGCGG	OBSCN	ENSG00000154358	0.33438581735874795	[30,28]	[19,14]	3	hSpCas9	positive selection	3190049
228212309	228212332		-	24336571	A375	resistance to PLX after 14 days	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	-0.7121815077407498	[33,30]	[8,8]	-8	hSpCas9	positive selection	3190050
228212027	228212050		+	24336571	A375	resistance to PLX after 14 days	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	1.7968593182393662	[37,44]	[59,74]	9	hSpCas9	positive selection	3190051
228214194	228214217		-	24336571	A375	viability after 7 days	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.507139598342413	[32]	[44,43]	7	hSpCas9	negative selection	3247840
228214418	228214441		-	24336571	A375	viability after 7 days	CCTCACCCGACACGCAGAACTGG	OBSCN	ENSG00000154358	-0.44112902138838006	[31]	[23,19]	-6	hSpCas9	negative selection	3247841
228214307	228214330		-	24336571	A375	viability after 7 days	CCTCCGCGGAGATGGCCACGCGG	OBSCN	ENSG00000154358	0.7487995951230078	[19]	[30,32]	9	hSpCas9	negative selection	3247842
228212309	228212332		-	24336571	A375	viability after 7 days	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.470716089305502	[20]	[29,26]	7	hSpCas9	negative selection	3247843
228212027	228212050		+	24336571	A375	viability after 7 days	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.6019618527641111	[32]	[50,44]	8	hSpCas9	negative selection	3247844
228214194	228214217		-	24336571	A375	viability after 14 days	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.4837531629056411	[32]	[39,45]	6	hSpCas9	negative selection	3305633
228214418	228214441		-	24336571	A375	viability after 14 days	CCTCACCCGACACGCAGAACTGG	OBSCN	ENSG00000154358	-0.5103299795547136	[31]	[25,14]	-6	hSpCas9	negative selection	3305634
228214307	228214330		-	24336571	A375	viability after 14 days	CCTCCGCGGAGATGGCCACGCGG	OBSCN	ENSG00000154358	0.6458470868218957	[19]	[30,28]	7	hSpCas9	negative selection	3305635
228212309	228212332		-	24336571	A375	viability after 14 days	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.6726909777539904	[20]	[33,30]	8	hSpCas9	negative selection	3305636
228212027	228212050		+	24336571	A375	viability after 14 days	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.4032641779457353	[32]	[37,44]	5	hSpCas9	negative selection	3305637
228215707	228215730	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.009460329249066228	[153,153]	[0,0]	0	hSpCas9	positive selection	3382871
228214387	228214410	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	1.3265888738829488	[60,60]	[0,0]	6	hSpCas9	positive selection	3382872
228215798	228215821	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	1.399345216318263	[57,57]	[0,0]	6	hSpCas9	positive selection	3382873
228246787	228246810	1	-	26780180	HT29	viability (Avana library 4 designs)	ACTGACCTGAAACATCCAGGTGG	OBSCN	ENSG00000154358	0.619670688119601	[]	[]	2	hSpCas9	negative selection	3445115
228278727	228278750	1	+	26780180	HT29	viability (Avana library 4 designs)	ATTGCCATGGAGAAGCACCGCGG	OBSCN	ENSG00000154358	0.415396953233126	[]	[]	1	hSpCas9	negative selection	3445116
228278744	228278767	1	-	26780180	HT29	viability (Avana library 4 designs)	CCTGACACTCCAGCACACCGCGG	OBSCN	ENSG00000154358	-0.437899879318449	[]	[]	-6	hSpCas9	negative selection	3445117
228215729	228215752	1	+	26780180	HT29	viability (Avana library 4 designs)	GCACACGCTCACCATCCGGGAGG	OBSCN	ENSG00000154358	0.510329841178731	[]	[]	2	hSpCas9	negative selection	3445118
228246787	228246810	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGACCTGAAACATCCAGGTGG	OBSCN	ENSG00000154358	0.00167000648447707	[]	[]	0	hSpCas9	negative selection	3537689
228278727	228278750	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTGCCATGGAGAAGCACCGCGG	OBSCN	ENSG00000154358	-2.1387327469359	[]	[]	-3	hSpCas9	negative selection	3537690
228278744	228278767	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGACACTCCAGCACACCGCGG	OBSCN	ENSG00000154358	-1.89578739709875	[]	[]	-2	hSpCas9	negative selection	3537691
228215729	228215752	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACACGCTCACCATCCGGGAGG	OBSCN	ENSG00000154358	1.49154791702278	[]	[]	2	hSpCas9	negative selection	3537692
228211786	228211809	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATCAGCCACAGTTCAGCGGGG	OBSCN	ENSG00000154358	-0.546613533977568	[]	[]	0	hSpCas9	negative selection	3537693
228216650	228216673	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	5.10579637855286	[]	[]	8	hSpCas9	negative selection	3537694
228246787	228246810	1	-	26780180	A375	viability (Avana lentiGuide)	ACTGACCTGAAACATCCAGGTGG	OBSCN	ENSG00000154358	2.47785904126938	[]	[]	2	hSpCas9	negative selection	3646348
228278727	228278750	1	+	26780180	A375	viability (Avana lentiGuide)	ATTGCCATGGAGAAGCACCGCGG	OBSCN	ENSG00000154358	2.87827559238918	[]	[]	3	hSpCas9	negative selection	3646349
228278744	228278767	1	-	26780180	A375	viability (Avana lentiGuide)	CCTGACACTCCAGCACACCGCGG	OBSCN	ENSG00000154358	-0.846631977106632	[]	[]	-1	hSpCas9	negative selection	3646350
228215729	228215752	1	+	26780180	A375	viability (Avana lentiGuide)	GCACACGCTCACCATCCGGGAGG	OBSCN	ENSG00000154358	9.03511154032947	[]	[]	6	hSpCas9	negative selection	3646351
228211786	228211809	1	+	26780180	A375	viability (Avana lentiGuide)	GGATCAGCCACAGTTCAGCGGGG	OBSCN	ENSG00000154358	13.9628794431655	[]	[]	7	hSpCas9	negative selection	3646352
228216650	228216673	1	+	26780180	A375	viability (Avana lentiGuide)	CTACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	5.56006366952332	[]	[]	5	hSpCas9	negative selection	3646353
228246787	228246810	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGACCTGAAACATCCAGGTGG	OBSCN	ENSG00000154358	-0.5126029440488555	[4]	[3,2]	-6	hSpCas9	positive selection	3755007
228278727	228278750	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTGCCATGGAGAAGCACCGCGG	OBSCN	ENSG00000154358	-0.17823028139418337	[5]	[5,4]	-3	hSpCas9	positive selection	3755008
228278744	228278767	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGACACTCCAGCACACCGCGG	OBSCN	ENSG00000154358	-0.3498811577250663	[5]	[5,3]	-5	hSpCas9	positive selection	3755009
228215729	228215752	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACACGCTCACCATCCGGGAGG	OBSCN	ENSG00000154358	0.22210052746076847	[5]	[6,5]	6	hSpCas9	positive selection	3755010
228211786	228211809	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATCAGCCACAGTTCAGCGGGG	OBSCN	ENSG00000154358	0.09469728853634829	[4]	[4,4]	2	hSpCas9	positive selection	3755011
228216650	228216673	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	0.3425528062542671	[5]	[6,6]	8	hSpCas9	positive selection	3755012
228246787	228246810	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGACCTGAAACATCCAGGTGG	OBSCN	ENSG00000154358	-0.06249103557425177	[5]	[3,5]	-1	hSpCas9	positive selection	3863614
228278727	228278750	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTGCCATGGAGAAGCACCGCGG	OBSCN	ENSG00000154358	-0.2849326295220344	[6]	[3,4]	-4	hSpCas9	positive selection	3863615
228278744	228278767	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGACACTCCAGCACACCGCGG	OBSCN	ENSG00000154358	0.19474440627427253	[6]	[7,6]	5	hSpCas9	positive selection	3863616
228215729	228215752	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACACGCTCACCATCCGGGAGG	OBSCN	ENSG00000154358	-0.06978993692692133	[6]	[4,5]	-1	hSpCas9	positive selection	3863617
228211786	228211809	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATCAGCCACAGTTCAGCGGGG	OBSCN	ENSG00000154358	-0.03598461822857255	[5]	[5,3]	0	hSpCas9	positive selection	3863618
228216650	228216673	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	-0.16990098205082532	[5]	[4,3]	-2	hSpCas9	positive selection	3863619
228214194	228214217	1	-	26780180	A375	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.711319118637619	[]	[]	2	hSpCas9	negative selection	3974756
228215707	228215730	1	+	26780180	A375	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	1.86537227165846	[]	[]	9	hSpCas9	negative selection	3974757
228215798	228215821	1	+	26780180	A375	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.7950423401458	[]	[]	3	hSpCas9	negative selection	3974758
228214387	228214410	1	-	26780180	A375	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.420023564428733	[]	[]	1	hSpCas9	negative selection	3974759
228212309	228212332	1	-	26780180	A375	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.594257249889645	[]	[]	1	hSpCas9	negative selection	3974760
228212027	228212050	1	+	26780180	A375	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.877085701587653	[]	[]	3	hSpCas9	negative selection	3974761
228214194	228214217	1	-	26780180	HT29	viability (GeCKOv2 library)	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.963670623609468	[]	[]	4	hSpCas9	negative selection	4082722
228215707	228215730	1	+	26780180	HT29	viability (GeCKOv2 library)	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	1.58818639974434	[]	[]	8	hSpCas9	negative selection	4082723
228215798	228215821	1	+	26780180	HT29	viability (GeCKOv2 library)	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	1.01425059518888	[]	[]	4	hSpCas9	negative selection	4082724
228214387	228214410	1	-	26780180	HT29	viability (GeCKOv2 library)	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.270052950794987	[]	[]	0	hSpCas9	negative selection	4082725
228212309	228212332	1	-	26780180	HT29	viability (GeCKOv2 library)	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.966036599103584	[]	[]	4	hSpCas9	negative selection	4082726
228212027	228212050	1	+	26780180	HT29	viability (GeCKOv2 library)	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.783027716059843	[]	[]	3	hSpCas9	negative selection	4082727
228214194	228214217	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.05458299454724219	[5]	[3,4]	1	hSpCas9	positive selection	4157018
228214418	228214441	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTCACCCGACACGCAGAACTGG	OBSCN	ENSG00000154358	0.1700019582356215	[4]	[2,3]	4	hSpCas9	positive selection	4157019
228214307	228214330	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTCCGCGGAGATGGCCACGCGG	OBSCN	ENSG00000154358	0.08686975233140637	[4]	[2,4]	2	hSpCas9	positive selection	4157020
228212309	228212332	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.27784444056884217	[4]	[3,3]	7	hSpCas9	positive selection	4157021
228212027	228212050	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.44847331486429376	[5]	[4,6]	8	hSpCas9	positive selection	4157022
228214194	228214217	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	-0.06240173178013281	[5]	[1,4,3,0]	-1	hSpCas9	positive selection	4221040
228214418	228214441	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTCACCCGACACGCAGAACTGG	OBSCN	ENSG00000154358	1.0525177127080325	[4]	[0,4,2,5]	7	hSpCas9	positive selection	4221041
228214307	228214330	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTCCGCGGAGATGGCCACGCGG	OBSCN	ENSG00000154358	1.205133937571903	[5]	[5,5,5,4]	8	hSpCas9	positive selection	4221042
228212309	228212332	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.8681352615030583	[4]	[2,0,5,3]	6	hSpCas9	positive selection	4221043
228212027	228212050	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.15159985766570971	[4]	[2,2,4,0]	1	hSpCas9	positive selection	4221044
228212027	228212050	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.10759127165322209	[3]	[3,2]	2	hSpCas9	positive selection	4286884
228212309	228212332	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.3287518555987363	[2]	[2,1]	6	hSpCas9	positive selection	4286885
228214194	228214217	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.4605315610993575	[2]	[3,2]	8	hSpCas9	positive selection	4286886
228215707	228215730	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.6625460493257346	[3]	[1,1]	-9	hSpCas9	positive selection	4351142
228214387	228214410	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.8138886440730109	[2]	[2,4]	9	hSpCas9	positive selection	4351143
228215798	228215821	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.11539520177350815	[2]	[1,0]	-2	hSpCas9	positive selection	4351144
228212029	228212051	1	-	27760321	OCIAML3	viability	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	-0.6140900975841042	[799,722]	[350,437]	-6	hSpCas9	negative selection	4424349
228212132	228212154	1	+	27760321	OCIAML3	viability	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.5293733507478287	[390,390]	[401,495]	6	hSpCas9	negative selection	4424350
228276453	228276475	1	+	27760321	OCIAML3	viability	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	1.2328307109745116	[50,587]	[617,644]	9	hSpCas9	negative selection	4424351
228277227	228277249	1	-	27760321	OCIAML3	viability	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	0.8022824105523376	[305,198]	[388,274]	8	hSpCas9	negative selection	4424352
228216651	228216673	1	+	27760321	OCIAML3	viability	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	0.2440907248302916	[824,679]	[586,832]	3	hSpCas9	negative selection	4424353
228212029	228212051	1	-	27760321	OCIAML2	viability	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	-0.25198031733416015	[799,722]	[433,625]	-3	hSpCas9	negative selection	4507812
228212132	228212154	1	+	27760321	OCIAML2	viability	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.4061115854331413	[390,390]	[407,436]	5	hSpCas9	negative selection	4507813
228276453	228276475	1	+	27760321	OCIAML2	viability	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	0.17979476861290689	[50,587]	[303,326]	2	hSpCas9	negative selection	4507814
228277227	228277249	1	-	27760321	OCIAML2	viability	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	1.3263540671299725	[305,198]	[400,641]	9	hSpCas9	negative selection	4507815
228216651	228216673	1	+	27760321	OCIAML2	viability	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	-0.373178257497873	[824,679]	[409,543]	-4	hSpCas9	negative selection	4507816
228212029	228212051	1	-	27760321	MV411	viability	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	0.6230667672982603	[799,722]	[863,636]	4	hSpCas9	negative selection	4591275
228212132	228212154	1	+	27760321	MV411	viability	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.5415064712898474	[390,390]	[353,410]	4	hSpCas9	negative selection	4591276
228276453	228276475	1	+	27760321	MV411	viability	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	1.516197395098348	[50,587]	[473,905]	9	hSpCas9	negative selection	4591277
228277227	228277249	1	-	27760321	MV411	viability	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	1.0059110624095549	[305,198]	[446,153]	7	hSpCas9	negative selection	4591278
228216651	228216673	1	+	27760321	MV411	viability	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	0.17955433746857874	[824,679]	[303,943]	1	hSpCas9	negative selection	4591279
228212029	228212051	1	-	27760321	HL60	viability	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	0.08262312494296131	[799,722]	[778,529]	1	hSpCas9	negative selection	4674738
228212132	228212154	1	+	27760321	HL60	viability	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	-0.08198823162564853	[390,390]	[343,258]	-1	hSpCas9	negative selection	4674739
228276453	228276475	1	+	27760321	HL60	viability	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	0.8842299299615792	[50,587]	[600,426]	8	hSpCas9	negative selection	4674740
228277227	228277249	1	-	27760321	HL60	viability	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	0.46132192200246364	[305,198]	[245,315]	5	hSpCas9	negative selection	4674741
228216651	228216673	1	+	27760321	HL60	viability	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	-0.33650591696114496	[824,679]	[552,411]	-4	hSpCas9	negative selection	4674742
228212029	228212051	1	-	27760321	HT1080	viability	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	0.46954122659426434	[722,563]	[374,332]	2	hSpCas9	negative selection	4758201
228212132	228212154	1	+	27760321	HT1080	viability	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	1.313784248639733	[390,304]	[441,237]	7	hSpCas9	negative selection	4758202
228276453	228276475	1	+	27760321	HT1080	viability	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	0.5282212053386253	[587,458]	[242,363]	2	hSpCas9	negative selection	4758203
228277227	228277249	1	-	27760321	HT1080	viability	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	2.3542257298651084	[198,154]	[528,175]	9	hSpCas9	negative selection	4758204
228216651	228216673	1	+	27760321	HT1080	viability	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	-0.7281817467941779	[679,530]	[126,165]	-3	hSpCas9	negative selection	4758205
228212029	228212051	1	-	27760321	HT29	viability after 7 days	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	0.08517817364204994	[722,563]	[798,1119,706]	1	hSpCas9	negative selection	4841664
228212132	228212154	1	+	27760321	HT29	viability after 7 days	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.06643748829014015	[390,304]	[579,571,274]	1	hSpCas9	negative selection	4841665
228276453	228276475	1	+	27760321	HT29	viability after 7 days	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	0.04146660392951862	[587,458]	[782,582,722]	0	hSpCas9	negative selection	4841666
228277227	228277249	1	-	27760321	HT29	viability after 7 days	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	0.014342601878926775	[198,154]	[372,216,122]	0	hSpCas9	negative selection	4841667
228216651	228216673	1	+	27760321	HT29	viability after 7 days	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	-0.3407525345132582	[679,530]	[815,439,615]	-5	hSpCas9	negative selection	4841668
228212029	228212051	1	-	27760321	HT29	viability after 25 days	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	0.4649079458412738	[722,563]	[935,1083,1029]	5	hSpCas9	negative selection	4925127
228212132	228212154	1	+	27760321	HT29	viability after 25 days	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.28970095122861794	[390,304]	[365,502,608]	3	hSpCas9	negative selection	4925128
228276453	228276475	1	+	27760321	HT29	viability after 25 days	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	0.831952361934577	[587,458]	[959,1165,1074]	8	hSpCas9	negative selection	4925129
228277227	228277249	1	-	27760321	HT29	viability after 25 days	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	0.7326422008292617	[198,154]	[304,365,338]	8	hSpCas9	negative selection	4925130
228216651	228216673	1	+	27760321	HT29	viability after 25 days	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	0.47411460950441675	[679,530]	[962,872,1055]	5	hSpCas9	negative selection	4925131
228212029	228212051	1	-	27760321	HT29	viability after 22 days	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	0.2408457052475096	[722,563]	[705,825,1111]	2	hSpCas9	negative selection	5008590
228212132	228212154	1	+	27760321	HT29	viability after 22 days	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.47739915634694985	[390,304]	[527,602,549]	5	hSpCas9	negative selection	5008591
228276453	228276475	1	+	27760321	HT29	viability after 22 days	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	0.8426524472760606	[587,458]	[1195,966,1089]	8	hSpCas9	negative selection	5008592
228277227	228277249	1	-	27760321	HT29	viability after 22 days	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	0.07515145401320145	[198,154]	[214,279,150]	0	hSpCas9	negative selection	5008593
228216651	228216673	1	+	27760321	HT29	viability after 22 days	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	0.5732832043130377	[679,530]	[997,1063,1063]	6	hSpCas9	negative selection	5008594
228212029	228212051	1	-	27760321	HT29	viability after 19 days	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	0.2606104051683841	[722,563]	[622,730,1248]	2	hSpCas9	negative selection	5092053
228212132	228212154	1	+	27760321	HT29	viability after 19 days	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	-0.0643987770112963	[390,304]	[349,370,415]	0	hSpCas9	negative selection	5092054
228276453	228276475	1	+	27760321	HT29	viability after 19 days	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	0.5673610437546266	[587,458]	[972,676,1014]	6	hSpCas9	negative selection	5092055
228277227	228277249	1	-	27760321	HT29	viability after 19 days	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	0.7185261451904578	[198,154]	[396,177,426]	7	hSpCas9	negative selection	5092056
228216651	228216673	1	+	27760321	HT29	viability after 19 days	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	0.3682632813441534	[679,530]	[769,705,1180]	3	hSpCas9	negative selection	5092057
228212029	228212051	1	-	27760321	HT29	viability after 16 days	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	0.015797692024812404	[722,563]	[923,458,825]	0	hSpCas9	negative selection	5175516
228212132	228212154	1	+	27760321	HT29	viability after 16 days	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.40808254259519605	[390,304]	[645,553,360]	4	hSpCas9	negative selection	5175517
228276453	228276475	1	+	27760321	HT29	viability after 16 days	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	0.7442452750351622	[587,458]	[845,1072,1008]	8	hSpCas9	negative selection	5175518
228277227	228277249	1	-	27760321	HT29	viability after 16 days	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	1.3280748571989611	[198,154]	[493,381,617]	9	hSpCas9	negative selection	5175519
228216651	228216673	1	+	27760321	HT29	viability after 16 days	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	0.3041266137351525	[679,530]	[955,509,1062]	3	hSpCas9	negative selection	5175520
228212029	228212051	1	-	27760321	HT29	viability after 13 days	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	0.07458294390993814	[722,563]	[620,668,1051]	0	hSpCas9	negative selection	5258979
228212132	228212154	1	+	27760321	HT29	viability after 13 days	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.10827027871097286	[390,304]	[485,344,471]	1	hSpCas9	negative selection	5258980
228276453	228276475	1	+	27760321	HT29	viability after 13 days	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	0.6326232173009545	[587,458]	[960,878,981]	7	hSpCas9	negative selection	5258981
228277227	228277249	1	-	27760321	HT29	viability after 13 days	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	0.6472382657236142	[198,154]	[246,399,317]	8	hSpCas9	negative selection	5258982
228216651	228216673	1	+	27760321	HT29	viability after 13 days	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	0.12324690028552232	[679,530]	[925,725,649]	1	hSpCas9	negative selection	5258983
228212029	228212051	1	-	27760321	HT29	viability after 10 days	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	-0.4937563577064915	[722,563]	[522,759,436]	-6	hSpCas9	negative selection	5342442
228212132	228212154	1	+	27760321	HT29	viability after 10 days	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	-0.21725492031973184	[390,304]	[311,377,429]	-3	hSpCas9	negative selection	5342443
228276453	228276475	1	+	27760321	HT29	viability after 10 days	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	0.5332552742895089	[587,458]	[846,997,992]	7	hSpCas9	negative selection	5342444
228277227	228277249	1	-	27760321	HT29	viability after 10 days	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	0.28696806930186214	[198,154]	[239,287,280]	4	hSpCas9	negative selection	5342445
228216651	228216673	1	+	27760321	HT29	viability after 10 days	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	0.29037143792410636	[679,530]	[637,699,1417]	4	hSpCas9	negative selection	5342446
228212029	228212051	1	-	27760321	MOLM13	viability	GCCTATGGCATTGCGCGCGCGG	OBSCN	ENSG00000154358	0.18095041850790583	[799,722]	[605,384]	1	hSpCas9	negative selection	5425905
228212132	228212154	1	+	27760321	MOLM13	viability	ACGTCCATCCGCGTGCGCGAGG	OBSCN	ENSG00000154358	0.5981534521097146	[390,390]	[347,323]	4	hSpCas9	negative selection	5425906
228276453	228276475	1	+	27760321	MOLM13	viability	GCCAGGTACGGCTCGTACGGGG	OBSCN	ENSG00000154358	0.8944398704425688	[50,587]	[361,356]	6	hSpCas9	negative selection	5425907
228277227	228277249	1	-	27760321	MOLM13	viability	GCGAACTCGCACCGGTAAATGG	OBSCN	ENSG00000154358	-0.8003272797130263	[305,198]	[118,47]	-5	hSpCas9	negative selection	5425908
228216651	228216673	1	+	27760321	MOLM13	viability	TACGAGTGCGTCAGCCGCGGGG	OBSCN	ENSG00000154358	0.14654016677058346	[824,679]	[490,447]	1	hSpCas9	negative selection	5425909
228208431	228208454	1	-	27661255	K562	viability	GGGTCAACTCCGGGGTAGAGGGG	OBSCN	ENSG00000154358	0.23963816393119144	[571,687]	[575,605]	7	dCas9-KRAB	negative selection	5498168
228212027	228212050	1	+	27260156	BXPC3	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.02827454259700085	[569]	[514,580,570,793]	0	hSpCas9	negative selection	5559344
228212309	228212332	1	-	27260156	BXPC3	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.25073423448076315	[260]	[327,305,292,375]	5	hSpCas9	negative selection	5559345
228214194	228214217	1	-	27260156	BXPC3	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.45538762553049267	[365]	[476,509,461,668]	8	hSpCas9	negative selection	5559346
228215707	228215730	1	+	27260156	BXPC3	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.2491068583342235	[611]	[482,445,558,692]	-5	hSpCas9	negative selection	5623602
228214387	228214410	1	-	27260156	BXPC3	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.28207953695368426	[240]	[377,203,268,378]	6	hSpCas9	negative selection	5623603
228215798	228215821	1	+	27260156	BXPC3	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.44786325348801936	[208]	[120,156,140,233]	-7	hSpCas9	negative selection	5623604
228212027	228212050	1	+	27260156	A673	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.07149587144478836	[569]	[821,563,677,833]	1	hSpCas9	negative selection	5680595
228212309	228212332	1	-	27260156	A673	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.2781342322330562	[260]	[373,366,438,335]	6	hSpCas9	negative selection	5680596
228214194	228214217	1	-	27260156	A673	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.3398553491706456	[365]	[587,484,640,511]	7	hSpCas9	negative selection	5680597
228215707	228215730	1	+	27260156	A673	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.2837175139897522	[611]	[628,643,653,480]	-6	hSpCas9	negative selection	5744853
228214387	228214410	1	-	27260156	A673	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.30694224090221556	[240]	[410,305,299,425]	7	hSpCas9	negative selection	5744854
228215798	228215821	1	+	27260156	A673	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.10408833459772704	[208]	[293,237,307,239]	2	hSpCas9	negative selection	5744855
228212027	228212050	1	+	27260156	A375	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-0.036507221988699906	[569]	[941,725,568,399]	0	hSpCas9	negative selection	5801846
228212309	228212332	1	-	27260156	A375	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.6024223285376374	[260]	[454,650,263,500]	8	hSpCas9	negative selection	5801847
228214194	228214217	1	-	27260156	A375	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.36910513893371644	[365]	[526,536,522,609]	5	hSpCas9	negative selection	5801848
228215707	228215730	1	+	27260156	A375	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.442260202644712	[611]	[461,611,598,449]	-6	hSpCas9	negative selection	5866104
228214387	228214410	1	-	27260156	A375	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.7026306350438687	[240]	[605,365,444,407]	9	hSpCas9	negative selection	5866105
228215798	228215821	1	+	27260156	A375	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.2965382676265449	[208]	[211,212,67,291]	-4	hSpCas9	negative selection	5866106
228212027	228212050	1	+	27260156	COLO741	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.25013015429525814	[569]	[1121,730,771]	5	hSpCas9	negative selection	5923097
228212309	228212332	1	-	27260156	COLO741	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.04380520584086067	[260]	[385,331,317]	0	hSpCas9	negative selection	5923098
228214194	228214217	1	-	27260156	COLO741	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.5377862312695416	[365]	[563,898,570]	9	hSpCas9	negative selection	5923099
228215707	228215730	1	+	27260156	COLO741	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.22204399852075724	[611]	[838,699,497]	-5	hSpCas9	negative selection	5987355
228214387	228214410	1	-	27260156	COLO741	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.43037671883596873	[240]	[472,238,527]	8	hSpCas9	negative selection	5987356
228215798	228215821	1	+	27260156	COLO741	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.18927425634215345	[208]	[204,250,242]	-4	hSpCas9	negative selection	5987357
228212027	228212050	1	+	27260156	CAL120	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.38293233390121056	[569]	[869,852,1040]	6	hSpCas9	negative selection	6044348
228212309	228212332	1	-	27260156	CAL120	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.3992503004538439	[260]	[554,438,311]	6	hSpCas9	negative selection	6044349
228214194	228214217	1	-	27260156	CAL120	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.5352427510472513	[365]	[903,423,687]	7	hSpCas9	negative selection	6044350
228215707	228215730	1	+	27260156	CAL120	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-1.0934191062872802	[611]	[286,468,304]	-8	hSpCas9	negative selection	6108606
228214387	228214410	1	-	27260156	CAL120	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.5161092863837222	[240]	[568,334,403]	7	hSpCas9	negative selection	6108607
228215798	228215821	1	+	27260156	CAL120	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.013095070020255006	[208]	[436,197,179]	0	hSpCas9	negative selection	6108608
228212027	228212050	1	+	27260156	CADOES1	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-0.321742947920457	[569]	[479,382,368,465]	-5	hSpCas9	negative selection	6165599
228212309	228212332	1	-	27260156	CADOES1	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.3659945302298832	[260]	[276,425,304,240]	6	hSpCas9	negative selection	6165600
228214194	228214217	1	-	27260156	CADOES1	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.4134096258119758	[365]	[573,356,553,322]	7	hSpCas9	negative selection	6165601
228215707	228215730	1	+	27260156	CADOES1	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.5656990950500739	[611]	[478,401,299,355]	-7	hSpCas9	negative selection	6229857
228214387	228214410	1	-	27260156	CADOES1	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.645615512970554	[240]	[373,374,343,307]	9	hSpCas9	negative selection	6229858
228215798	228215821	1	+	27260156	CADOES1	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.014888885311473699	[208]	[141,164,259,202]	0	hSpCas9	negative selection	6229859
228212027	228212050	1	+	27260156	EWS502	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.0050374764152739115	[569]	[648,611,687,456]	0	hSpCas9	negative selection	6286850
228212309	228212332	1	-	27260156	EWS502	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.6618518255780543	[260]	[365,414,584,389]	9	hSpCas9	negative selection	6286851
228214194	228214217	1	-	27260156	EWS502	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.5353799002448539	[365]	[645,578,584,413]	8	hSpCas9	negative selection	6286852
228215707	228215730	1	+	27260156	EWS502	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.2501136326347996	[611]	[592,452,561,569]	-4	hSpCas9	negative selection	6351108
228214387	228214410	1	-	27260156	EWS502	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.4468491241658411	[240]	[425,221,352,387]	7	hSpCas9	negative selection	6351109
228215798	228215821	1	+	27260156	EWS502	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.029501177036484805	[208]	[353,163,220,144]	0	hSpCas9	negative selection	6351110
228212027	228212050	1	+	27260156	EW8	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.2977587271079977	[569]	[684,586,561,449]	5	hSpCas9	negative selection	6408101
228212309	228212332	1	-	27260156	EW8	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.10121787622573786	[260]	[201,238,281,171]	1	hSpCas9	negative selection	6408102
228214194	228214217	1	-	27260156	EW8	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.4802704309419055	[365]	[494,345,326,508]	8	hSpCas9	negative selection	6408103
228215707	228215730	1	+	27260156	EW8	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.31666238567783156	[611]	[353,423,367,445]	-5	hSpCas9	negative selection	6472359
228214387	228214410	1	-	27260156	EW8	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.3217067131010267	[240]	[289,301,161,240]	6	hSpCas9	negative selection	6472360
228215798	228215821	1	+	27260156	EW8	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.30825561316972383	[208]	[211,188,235,196]	5	hSpCas9	negative selection	6472361
228212027	228212050	1	+	27260156	CORL105	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-0.13024211606311237	[569]	[719,517,695,523]	-2	hSpCas9	negative selection	6529352
228212309	228212332	1	-	27260156	CORL105	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.6645648627589329	[260]	[510,450,448,521]	9	hSpCas9	negative selection	6529353
228214194	228214217	1	-	27260156	CORL105	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.6843127477547907	[365]	[664,549,912,662]	9	hSpCas9	negative selection	6529354
228215707	228215730	1	+	27260156	CORL105	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.48190253410690936	[611]	[621,372,617,461]	-7	hSpCas9	negative selection	6593610
228214387	228214410	1	-	27260156	CORL105	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.6042539947195205	[240]	[599,301,478,350]	9	hSpCas9	negative selection	6593611
228215798	228215821	1	+	27260156	CORL105	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.023785726192868673	[208]	[159,236,225,364]	0	hSpCas9	negative selection	6593612
228212027	228212050	1	+	27260156	HS294T	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.5641801165577307	[569]	[265,292,320,449]	7	hSpCas9	negative selection	6650603
228212309	228212332	1	-	27260156	HS294T	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.5528303159882755	[260]	[162,172,146,97]	7	hSpCas9	negative selection	6650604
228214194	228214217	1	-	27260156	HS294T	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.5666036072136702	[365]	[192,136,180,354]	7	hSpCas9	negative selection	6650605
228215707	228215730	1	+	27260156	HS294T	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.6224066469249002	[611]	[106,233,126,146]	-7	hSpCas9	negative selection	6714861
228214387	228214410	1	-	27260156	HS294T	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.582988074684589	[240]	[155,124,154,116]	7	hSpCas9	negative selection	6714862
228215798	228215821	1	+	27260156	HS294T	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.7905084132871429	[208]	[41,62,37,42]	-8	hSpCas9	negative selection	6714863
228212027	228212050	1	+	27260156	HCC44	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.31222139053855874	[569]	[990,403,1049,864]	5	hSpCas9	negative selection	6771854
228212309	228212332	1	-	27260156	HCC44	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.5277850074636878	[260]	[525,319,559,342]	8	hSpCas9	negative selection	6771855
228214194	228214217	1	-	27260156	HCC44	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.5581253549511673	[365]	[482,791,496,603]	8	hSpCas9	negative selection	6771856
228215707	228215730	1	+	27260156	HCC44	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.49712516514671473	[611]	[707,408,396,459]	-6	hSpCas9	negative selection	6836112
228214387	228214410	1	-	27260156	HCC44	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.46014276536487875	[240]	[426,317,348,409]	7	hSpCas9	negative selection	6836113
228215798	228215821	1	+	27260156	HCC44	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.1855504055171031	[208]	[172,231,207,209]	-3	hSpCas9	negative selection	6836114
228212027	228212050	1	+	27260156	G402	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-0.2005259788085877	[569]	[952,561,570,390]	-3	hSpCas9	negative selection	6893105
228212309	228212332	1	-	27260156	G402	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.38125381904608596	[260]	[392,205,409,622]	5	hSpCas9	negative selection	6893106
228214194	228214217	1	-	27260156	G402	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.23978721579589646	[365]	[702,396,367,650]	3	hSpCas9	negative selection	6893107
228215707	228215730	1	+	27260156	G402	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.4106304492032602	[611]	[419,622,579,602]	-5	hSpCas9	negative selection	6957363
228214387	228214410	1	-	27260156	G402	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.996921484397537	[240]	[426,807,639,465]	9	hSpCas9	negative selection	6957364
228215798	228215821	1	+	27260156	G402	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.07505710010007838	[208]	[195,167,229,453]	0	hSpCas9	negative selection	6957365
228212027	228212050	1	+	27260156	L33	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.2560274460735236	[569]	[662,270,433,707]	5	hSpCas9	negative selection	7014356
228212309	228212332	1	-	27260156	L33	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.34308198618815566	[260]	[360,108,181,405]	7	hSpCas9	negative selection	7014357
228214194	228214217	1	-	27260156	L33	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.4381944989013689	[365]	[486,245,302,414]	8	hSpCas9	negative selection	7014358
228215707	228215730	1	+	27260156	L33	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.5089963198247518	[611]	[405,192,303,360]	-8	hSpCas9	negative selection	7078614
228214387	228214410	1	-	27260156	L33	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.03002500695318111	[240]	[295,84,177,196]	0	hSpCas9	negative selection	7078615
228215798	228215821	1	+	27260156	L33	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.2603840301115705	[208]	[147,100,131,94]	-6	hSpCas9	negative selection	7078616
228212027	228212050	1	+	27260156	K562	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.4434148537999775	[569]	[637,606,711,772]	5	hSpCas9	negative selection	7135607
228212309	228212332	1	-	27260156	K562	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.5090647861304534	[260]	[242,284,641,157]	6	hSpCas9	negative selection	7135608
228214194	228214217	1	-	27260156	K562	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.5339448882451371	[365]	[351,293,553,639]	6	hSpCas9	negative selection	7135609
228215707	228215730	1	+	27260156	K562	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.28986361899705304	[611]	[468,663,91,550]	-4	hSpCas9	negative selection	7199865
228214387	228214410	1	-	27260156	K562	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.4513059883423166	[240]	[169,335,317,331]	6	hSpCas9	negative selection	7199866
228215798	228215821	1	+	27260156	K562	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.9862748027152148	[208]	[98,167,41,71]	-8	hSpCas9	negative selection	7199867
228212027	228212050	1	+	27260156	HT29	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.12105826700231298	[569]	[827,774,791,635]	2	hSpCas9	negative selection	7256858
228212309	228212332	1	-	27260156	HT29	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.15398544198169528	[260]	[458,385,361,228]	3	hSpCas9	negative selection	7256859
228214194	228214217	1	-	27260156	HT29	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.4304014237472123	[365]	[766,654,492,507]	8	hSpCas9	negative selection	7256860
228215707	228215730	1	+	27260156	HT29	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.33775473953406726	[611]	[601,727,593,455]	-6	hSpCas9	negative selection	7321116
228214387	228214410	1	-	27260156	HT29	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.3587224329121861	[240]	[350,302,490,349]	7	hSpCas9	negative selection	7321117
228215798	228215821	1	+	27260156	HT29	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.21168931674338176	[208]	[168,301,258,156]	-4	hSpCas9	negative selection	7321118
228212027	228212050	1	+	27260156	MHHES1	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-0.27742863953951996	[569]	[479,749,591,344]	-5	hSpCas9	negative selection	7378109
228212309	228212332	1	-	27260156	MHHES1	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.4921719406347418	[260]	[268,526,411,426]	8	hSpCas9	negative selection	7378110
228214194	228214217	1	-	27260156	MHHES1	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.5476321587416767	[365]	[865,479,604,490]	8	hSpCas9	negative selection	7378111
228215707	228215730	1	+	27260156	MHHES1	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.2447693265879759	[611]	[588,769,522,475]	-4	hSpCas9	negative selection	7442367
228214387	228214410	1	-	27260156	MHHES1	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.4883582022902785	[240]	[497,431,375,256]	8	hSpCas9	negative selection	7442368
228215798	228215821	1	+	27260156	MHHES1	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.1850741203773143	[208]	[162,316,142,205]	-3	hSpCas9	negative selection	7442369
228212027	228212050	1	+	27260156	MEWO	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.07164457570852945	[569]	[570,598,512]	1	hSpCas9	negative selection	7499360
228212309	228212332	1	-	27260156	MEWO	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.40101307550251336	[260]	[380,435,160]	8	hSpCas9	negative selection	7499361
228214194	228214217	1	-	27260156	MEWO	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.4555897261076436	[365]	[777,337,352]	8	hSpCas9	negative selection	7499362
228215707	228215730	1	+	27260156	MEWO	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.2793561366198014	[611]	[606,348,485]	-6	hSpCas9	negative selection	7563618
228214387	228214410	1	-	27260156	MEWO	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.12140502064610814	[240]	[331,151,268]	2	hSpCas9	negative selection	7563619
228215798	228215821	1	+	27260156	MEWO	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.1320459600520174	[208]	[209,202,228]	3	hSpCas9	negative selection	7563620
228212027	228212050	1	+	27260156	LNCAPCLONEFGC	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.11340343277002318	[569]	[516,538,733,471]	1	hSpCas9	negative selection	7620611
228212309	228212332	1	-	27260156	LNCAPCLONEFGC	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.45821742905431356	[260]	[319,209,420,369]	7	hSpCas9	negative selection	7620612
228214194	228214217	1	-	27260156	LNCAPCLONEFGC	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.5519002302992757	[365]	[475,435,550,493]	8	hSpCas9	negative selection	7620613
228215707	228215730	1	+	27260156	LNCAPCLONEFGC	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.19567757910777261	[611]	[543,505,427,446]	-3	hSpCas9	negative selection	7684869
228214387	228214410	1	-	27260156	LNCAPCLONEFGC	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.48247631119837536	[240]	[335,264,352,274]	7	hSpCas9	negative selection	7684870
228215798	228215821	1	+	27260156	LNCAPCLONEFGC	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.11185049244212375	[208]	[150,210,115,211]	-2	hSpCas9	negative selection	7684871
228212027	228212050	1	+	27260156	PANC0327	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.11205454643596996	[569]	[660,649,561,311]	1	hSpCas9	negative selection	7741862
228212309	228212332	1	-	27260156	PANC0327	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.6530160943939314	[260]	[365,249,366,489]	8	hSpCas9	negative selection	7741863
228214194	228214217	1	-	27260156	PANC0327	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.7320369624577315	[365]	[525,393,751,505]	9	hSpCas9	negative selection	7741864
228215707	228215730	1	+	27260156	PANC0327	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.2344602342373894	[611]	[556,408,498,397]	-3	hSpCas9	negative selection	7806120
228214387	228214410	1	-	27260156	PANC0327	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.5969445499256845	[240]	[433,340,321,204]	8	hSpCas9	negative selection	7806121
228215798	228215821	1	+	27260156	PANC0327	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.21878273223116884	[208]	[163,208,115,142]	-3	hSpCas9	negative selection	7806122
228212027	228212050	1	+	27260156	NCIH2009	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.009249206136274224	[569]	[1053,583,818]	0	hSpCas9	negative selection	7863113
228212309	228212332	1	-	27260156	NCIH2009	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.4116862222603198	[260]	[666,450,372]	5	hSpCas9	negative selection	7863114
228214194	228214217	1	-	27260156	NCIH2009	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	1.0583188792929814	[365]	[1368,1010,873]	9	hSpCas9	negative selection	7863115
228215707	228215730	1	+	27260156	NCIH2009	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.2002880564422915	[611]	[732,919,572]	-3	hSpCas9	negative selection	7927371
228214387	228214410	1	-	27260156	NCIH2009	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.25486310225700237	[240]	[484,406,328]	3	hSpCas9	negative selection	7927372
228215798	228215821	1	+	27260156	NCIH2009	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.7036870340755355	[208]	[120,181,222]	-7	hSpCas9	negative selection	7927373
228212027	228212050	1	+	27260156	NCIH1373	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.4873248155477446	[569]	[1166,564,753,312]	5	hSpCas9	negative selection	7984364
228212309	228212332	1	-	27260156	NCIH1373	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	1.0735662042995404	[260]	[691,526,595,175]	9	hSpCas9	negative selection	7984365
228214194	228214217	1	-	27260156	NCIH1373	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.39126209110672067	[365]	[498,419,577,174]	4	hSpCas9	negative selection	7984366
228215707	228215730	1	+	27260156	NCIH1373	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.32000168474932655	[611]	[1233,281,440,95]	-3	hSpCas9	negative selection	8048622
228214387	228214410	1	-	27260156	NCIH1373	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.996304562565118	[240]	[512,577,502,144]	8	hSpCas9	negative selection	8048623
228215798	228215821	1	+	27260156	NCIH1373	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-1.5060317629653823	[208]	[43,95,104,19]	-9	hSpCas9	negative selection	8048624
228212027	228212050	1	+	27260156	PATU8902	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-0.6422202073885497	[569]	[568,585,321,613]	-6	hSpCas9	negative selection	8105615
228212309	228212332	1	-	27260156	PATU8902	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.8753006531502925	[260]	[741,461,881,497]	8	hSpCas9	negative selection	8105616
228214194	228214217	1	-	27260156	PATU8902	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.724638393680464	[365]	[1021,965,431,1074]	7	hSpCas9	negative selection	8105617
228215707	228215730	1	+	27260156	PATU8902	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.26031741440112904	[611]	[1063,602,370,909]	-3	hSpCas9	negative selection	8169873
228214387	228214410	1	-	27260156	PATU8902	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.7409445035828879	[240]	[495,1254,181,386]	7	hSpCas9	negative selection	8169874
228215798	228215821	1	+	27260156	PATU8902	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.5033256376814266	[208]	[253,165,22,452]	-5	hSpCas9	negative selection	8169875
228212027	228212050	1	+	27260156	PANC1	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-0.08732065047556453	[569]	[576,488,399,384]	-1	hSpCas9	negative selection	8226866
228212309	228212332	1	-	27260156	PANC1	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.6198974548193357	[260]	[280,623,373,179]	8	hSpCas9	negative selection	8226867
228214194	228214217	1	-	27260156	PANC1	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.7055756342058619	[365]	[474,558,602,429]	9	hSpCas9	negative selection	8226868
228215707	228215730	1	+	27260156	PANC1	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.29348847897612595	[611]	[364,596,440,353]	-5	hSpCas9	negative selection	8291124
228214387	228214410	1	-	27260156	PANC1	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.5624508075739765	[240]	[354,313,330,230]	8	hSpCas9	negative selection	8291125
228215798	228215821	1	+	27260156	PANC1	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.3097285106707035	[208]	[113,172,181,118]	-5	hSpCas9	negative selection	8291126
228212027	228212050	1	+	27260156	PANC0813	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.09080316196230082	[569]	[627,725,734,751]	1	hSpCas9	negative selection	8348117
228212309	228212332	1	-	27260156	PANC0813	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.27867358522786057	[260]	[527,409,249,315]	4	hSpCas9	negative selection	8348118
228214194	228214217	1	-	27260156	PANC0813	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.6835814264999895	[365]	[867,669,760,489]	9	hSpCas9	negative selection	8348119
228215707	228215730	1	+	27260156	PANC0813	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.42827235795373025	[611]	[650,402,677,421]	-6	hSpCas9	negative selection	8412375
228214387	228214410	1	-	27260156	PANC0813	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.3965735655244619	[240]	[399,422,345,325]	6	hSpCas9	negative selection	8412376
228215798	228215821	1	+	27260156	PANC0813	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-1.0204919357439592	[208]	[130,120,115,116]	-8	hSpCas9	negative selection	8412377
228212027	228212050	1	+	27260156	RDES	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.09344230681864168	[569]	[538,722,747,818]	1	hSpCas9	negative selection	8469368
228212309	228212332	1	-	27260156	RDES	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.5725190892686745	[260]	[272,412,485,679]	8	hSpCas9	negative selection	8469369
228214194	228214217	1	-	27260156	RDES	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.4296189255850397	[365]	[500,429,619,757]	7	hSpCas9	negative selection	8469370
228215707	228215730	1	+	27260156	RDES	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.30473751735802135	[611]	[475,474,648,716]	-5	hSpCas9	negative selection	8533626
228214387	228214410	1	-	27260156	RDES	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.42546118784563436	[240]	[234,387,351,559]	6	hSpCas9	negative selection	8533627
228215798	228215821	1	+	27260156	RDES	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.005351316507031356	[208]	[183,194,276,325]	0	hSpCas9	negative selection	8533628
228212027	228212050	1	+	27260156	PC3	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.3322583571060674	[569]	[407,638,1595,633]	7	hSpCas9	negative selection	8590619
228212309	228212332	1	-	27260156	PC3	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.0006338881455192347	[260]	[166,301,400,236]	0	hSpCas9	negative selection	8590620
228214194	228214217	1	-	27260156	PC3	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.5120169301017357	[365]	[341,455,1006,493]	9	hSpCas9	negative selection	8590621
228215707	228215730	1	+	27260156	PC3	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.8520209701699902	[611]	[249,304,567,319]	-9	hSpCas9	negative selection	8654877
228214387	228214410	1	-	27260156	PC3	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.18804984609742648	[240]	[161,212,534,315]	4	hSpCas9	negative selection	8654878
228215798	228215821	1	+	27260156	PC3	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.19376084523503712	[208]	[202,224,345,204]	4	hSpCas9	negative selection	8654879
228212027	228212050	1	+	27260156	PATU8988T	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.2016289074086356	[569]	[669,465,641,748]	3	hSpCas9	negative selection	8711870
228212309	228212332	1	-	27260156	PATU8988T	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.2819652572888872	[260]	[189,286,329,426]	5	hSpCas9	negative selection	8711871
228214194	228214217	1	-	27260156	PATU8988T	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.6241311741540367	[365]	[338,616,547,694]	8	hSpCas9	negative selection	8711872
228215707	228215730	1	+	27260156	PATU8988T	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.16584512396319998	[611]	[473,645,310,705]	-3	hSpCas9	negative selection	8776128
228214387	228214410	1	-	27260156	PATU8988T	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.45661532774900604	[240]	[289,331,270,392]	7	hSpCas9	negative selection	8776129
228215798	228215821	1	+	27260156	PATU8988T	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.06437475515188673	[208]	[116,126,331,187]	-1	hSpCas9	negative selection	8776130
228212027	228212050	1	+	27260156	T47D	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-0.02886848541028375	[569]	[676,575,686,669]	0	hSpCas9	negative selection	8833121
228212309	228212332	1	-	27260156	T47D	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.07209903525423245	[260]	[278,301,355,342]	1	hSpCas9	negative selection	8833122
228214194	228214217	1	-	27260156	T47D	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.342918043832736	[365]	[592,441,573,562]	7	hSpCas9	negative selection	8833123
228215707	228215730	1	+	27260156	T47D	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.5841443293774998	[611]	[574,416,465,448]	-8	hSpCas9	negative selection	8897379
228214387	228214410	1	-	27260156	T47D	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.5862518804486623	[240]	[497,306,417,474]	9	hSpCas9	negative selection	8897380
228215798	228215821	1	+	27260156	T47D	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.2523930859137322	[208]	[278,166,163,211]	-5	hSpCas9	negative selection	8897381
228212027	228212050	1	+	27260156	SU8686	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.036068138109498105	[569]	[683,563,580,453]	0	hSpCas9	negative selection	8954372
228212309	228212332	1	-	27260156	SU8686	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.2524450315876867	[260]	[192,303,443,306]	4	hSpCas9	negative selection	8954373
228214194	228214217	1	-	27260156	SU8686	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.5806536509346374	[365]	[513,620,460,564]	8	hSpCas9	negative selection	8954374
228215707	228215730	1	+	27260156	SU8686	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.2664764439844259	[611]	[408,552,452,620]	-4	hSpCas9	negative selection	9018630
228214387	228214410	1	-	27260156	SU8686	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.5318798978683684	[240]	[344,295,302,458]	8	hSpCas9	negative selection	9018631
228215798	228215821	1	+	27260156	SU8686	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.5893580234616989	[208]	[145,187,95,105]	-7	hSpCas9	negative selection	9018632
228212027	228212050	1	+	27260156	SKES1	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.11798956675429251	[569]	[819,608,630,448]	2	hSpCas9	negative selection	9075623
228212309	228212332	1	-	27260156	SKES1	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.4627799564569812	[260]	[625,275,306,261]	8	hSpCas9	negative selection	9075624
228214194	228214217	1	-	27260156	SKES1	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.4399884587636911	[365]	[490,613,546,353]	8	hSpCas9	negative selection	9075625
228215707	228215730	1	+	27260156	SKES1	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.46708035225666916	[611]	[357,555,455,398]	-8	hSpCas9	negative selection	9139881
228214387	228214410	1	-	27260156	SKES1	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.43693219817587137	[240]	[486,310,241,284]	8	hSpCas9	negative selection	9139882
228215798	228215821	1	+	27260156	SKES1	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.11768116832522768	[208]	[301,239,223,156]	2	hSpCas9	negative selection	9139883
228212027	228212050	1	+	27260156	TOV112D	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	0.41427642096578715	[569]	[982,568,904,561]	7	hSpCas9	negative selection	9196874
228212309	228212332	1	-	27260156	TOV112D	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.18701664209960045	[260]	[361,333,165,340]	3	hSpCas9	negative selection	9196875
228214194	228214217	1	-	27260156	TOV112D	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.3742653928645222	[365]	[371,725,313,538]	7	hSpCas9	negative selection	9196876
228215707	228215730	1	+	27260156	TOV112D	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	0.04683521849965622	[611]	[462,715,373,974]	0	hSpCas9	negative selection	9261132
228214387	228214410	1	-	27260156	TOV112D	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.4143647798509049	[240]	[302,401,444,158]	7	hSpCas9	negative selection	9261133
228215798	228215821	1	+	27260156	TOV112D	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.2114719848729678	[208]	[239,162,218,324]	4	hSpCas9	negative selection	9261134
228212027	228212050	1	+	27260156	TC71	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-0.03736069263491992	[569]	[555,598,612,614]	-1	hSpCas9	negative selection	9318125
228212309	228212332	1	-	27260156	TC71	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	-0.09427187116141922	[260]	[262,280,221,284]	-2	hSpCas9	negative selection	9318126
228214194	228214217	1	-	27260156	TC71	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.46461876143937947	[365]	[607,516,572,459]	9	hSpCas9	negative selection	9318127
228215707	228215730	1	+	27260156	TC71	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.4476323074922112	[611]	[449,510,449,516]	-8	hSpCas9	negative selection	9382383
228214387	228214410	1	-	27260156	TC71	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.30427513199704614	[240]	[262,357,312,344]	7	hSpCas9	negative selection	9382384
228215798	228215821	1	+	27260156	TC71	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	0.28111083809416926	[208]	[244,361,226,255]	6	hSpCas9	negative selection	9382385
228212027	228212050	1	+	27260156	TC32	viability	TGCCGCGCGCGCAATGCCATAGG	OBSCN	ENSG00000154358	-0.3397987392002282	[569]	[467,188,560,566]	-6	hSpCas9	negative selection	9439376
228212309	228212332	1	-	27260156	TC32	viability	TCGTAAGTGCCGCCGTCGCGCGG	OBSCN	ENSG00000154358	0.4969035680730283	[260]	[268,302,473,366]	8	hSpCas9	negative selection	9439377
228214194	228214217	1	-	27260156	TC32	viability	ACGCGCACCGCCGTCTTCCGAGG	OBSCN	ENSG00000154358	0.12600141252856556	[365]	[295,243,572,466]	2	hSpCas9	negative selection	9439378
228215707	228215730	1	+	27260156	TC32	viability	AGATCCACTGTGATCGCACCCGG	OBSCN	ENSG00000154358	-0.4038737529604676	[611]	[450,422,417,415]	-6	hSpCas9	negative selection	9503634
228214387	228214410	1	-	27260156	TC32	viability	CTGGCAGTCGCCAGCCATAAAGG	OBSCN	ENSG00000154358	0.5282221359756776	[240]	[350,195,447,361]	8	hSpCas9	negative selection	9503635
228215798	228215821	1	+	27260156	TC32	viability	CATTGAGAGCAGCATCCGGATGG	OBSCN	ENSG00000154358	-0.2218641439093505	[208]	[186,113,221,167]	-4	hSpCas9	negative selection	9503636
228212281	228212304	1	+	27869803	HPAFII	viability after 27 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	0.8100265199700134	[78]	[44,95,NaN]	6	hSpCas9	negative selection	9532502
228214187	228214210	1	+	27869803	HPAFII	viability after 27 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	-0.7118861933487473	[178]	[75,41,NaN]	-5	hSpCas9	negative selection	9532503
228214820	228214843	1	+	27869803	HPAFII	viability after 27 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	0.39492285567747343	[244]	[176,162,NaN]	3	hSpCas9	negative selection	9532504
228215637	228215660	1	+	27869803	HPAFII	viability after 27 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	-0.12268067201474642	[76]	[40,33,NaN]	-1	hSpCas9	negative selection	9532505
228216520	228216543	1	+	27869803	HPAFII	viability after 27 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	0.8166351421086437	[182]	[25,288,NaN]	6	hSpCas9	negative selection	9532506
228217155	228217178	1	+	27869803	HPAFII	viability after 27 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	-0.5181204483994855	[182]	[130,13,NaN]	-4	hSpCas9	negative selection	9532507
228212281	228212304	1	+	27869803	HPAFII	viability after 15 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	0.6718899346102343	[78]	[117,145,NaN]	7	hSpCas9	negative selection	9614951
228214187	228214210	1	+	27869803	HPAFII	viability after 15 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.6280216006708909	[178]	[374,248,NaN]	7	hSpCas9	negative selection	9614952
228214820	228214843	1	+	27869803	HPAFII	viability after 15 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	0.28561873581803743	[244]	[381,282,NaN]	3	hSpCas9	negative selection	9614953
228215637	228215660	1	+	27869803	HPAFII	viability after 15 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	0.3874035223060268	[76]	[61,136,NaN]	4	hSpCas9	negative selection	9614954
228216520	228216543	1	+	27869803	HPAFII	viability after 15 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	-0.11137538573158079	[182]	[149,201,NaN]	-1	hSpCas9	negative selection	9614955
228217155	228217178	1	+	27869803	HPAFII	viability after 15 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	-0.3204661036509321	[182]	[331,48,NaN]	-4	hSpCas9	negative selection	9614956
228212281	228212304	1	+	27869803	ASPC1	viability after 36 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	-1.7243732831396987	[101]	[3,4,19]	-9	hSpCas9	negative selection	9697400
228214187	228214210	1	+	27869803	ASPC1	viability after 36 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	-0.1708457566289341	[472]	[295,63,105]	-2	hSpCas9	negative selection	9697401
228214820	228214843	1	+	27869803	ASPC1	viability after 36 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	1.410504216381161	[488]	[129,1016,228]	9	hSpCas9	negative selection	9697402
228215637	228215660	1	+	27869803	ASPC1	viability after 36 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	0.6716157807517957	[110]	[61,53,66]	6	hSpCas9	negative selection	9697403
228216520	228216543	1	+	27869803	ASPC1	viability after 36 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	0.38267600408732283	[444]	[71,107,366]	4	hSpCas9	negative selection	9697404
228217155	228217178	1	+	27869803	ASPC1	viability after 36 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	1.4394102532578754	[335]	[473,242,264]	9	hSpCas9	negative selection	9697405
228212281	228212304	1	+	27869803	PATU8988S	viability after 35 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	-0.509075079959366	[121]	[45,22,NaN]	-5	hSpCas9	negative selection	9779849
228214187	228214210	1	+	27869803	PATU8988S	viability after 35 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	0.03976205190638227	[392]	[251,72,NaN]	0	hSpCas9	negative selection	9779850
228214820	228214843	1	+	27869803	PATU8988S	viability after 35 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-0.1576135695585001	[500]	[134,226,NaN]	-2	hSpCas9	negative selection	9779851
228215637	228215660	1	+	27869803	PATU8988S	viability after 35 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	1.1815067773640064	[86]	[67,90,NaN]	9	hSpCas9	negative selection	9779852
228216520	228216543	1	+	27869803	PATU8988S	viability after 35 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	0.4792667266288085	[327]	[251,115,NaN]	5	hSpCas9	negative selection	9779853
228217155	228217178	1	+	27869803	PATU8988S	viability after 35 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.44506127138972884	[363]	[233,164,NaN]	5	hSpCas9	negative selection	9779854
228212281	228212304	1	+	27869803	PATU8988S	viability after 31 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	-1.4438269965625867	[121]	[27,4,NaN]	-8	hSpCas9	negative selection	9862298
228214187	228214210	1	+	27869803	PATU8988S	viability after 31 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	-0.42300828763369025	[392]	[126,103,NaN]	-5	hSpCas9	negative selection	9862299
228214820	228214843	1	+	27869803	PATU8988S	viability after 31 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-1.1000187763424782	[500]	[68,123,NaN]	-8	hSpCas9	negative selection	9862300
228215637	228215660	1	+	27869803	PATU8988S	viability after 31 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	1.7339834209083158	[86]	[99,134,NaN]	9	hSpCas9	negative selection	9862301
228216520	228216543	1	+	27869803	PATU8988S	viability after 31 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	0.5089882979525912	[327]	[175,198,NaN]	6	hSpCas9	negative selection	9862302
228217155	228217178	1	+	27869803	PATU8988S	viability after 31 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.39873665824127963	[363]	[138,257,NaN]	5	hSpCas9	negative selection	9862303
228212281	228212304	1	+	27869803	HPAFII	viability after 35 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	1.37989850016517	[78]	[33,182,NaN]	8	hSpCas9	negative selection	9944747
228214187	228214210	1	+	27869803	HPAFII	viability after 35 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	-0.899406120760434	[178]	[33,64,NaN]	-5	hSpCas9	negative selection	9944748
228214820	228214843	1	+	27869803	HPAFII	viability after 35 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	-0.26473091867139964	[244]	[106,98,NaN]	-2	hSpCas9	negative selection	9944749
228215637	228215660	1	+	27869803	HPAFII	viability after 35 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	0.013948737673513012	[76]	[52,23,NaN]	0	hSpCas9	negative selection	9944750
228216520	228216543	1	+	27869803	HPAFII	viability after 35 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	0.6985868395305992	[182]	[28,286,NaN]	4	hSpCas9	negative selection	9944751
228217155	228217178	1	+	27869803	HPAFII	viability after 35 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	-0.06211277431166118	[182]	[155,12,NaN]	0	hSpCas9	negative selection	9944752
228212281	228212304	1	+	27869803	HPAFII	viability after 31 days	AAGTGCGCTGCGCATTCGGGCGG	OBSCN	ENSG00000154358	1.0233887292063106	[78]	[36,147,NaN]	7	hSpCas9	negative selection	10027196
228214187	228214210	1	+	27869803	HPAFII	viability after 31 days	AAAGCTCCCTCGGAAGACGGCGG	OBSCN	ENSG00000154358	-0.36980635328428657	[178]	[71,83,NaN]	-2	hSpCas9	negative selection	10027197
228214820	228214843	1	+	27869803	HPAFII	viability after 31 days	TGGATCCTGTGGTAAAGGCCAGG	OBSCN	ENSG00000154358	0.5976187978139793	[244]	[175,242,NaN]	4	hSpCas9	negative selection	10027198
228215637	228215660	1	+	27869803	HPAFII	viability after 31 days	GACCTCACGGTGGCCTCAGCGGG	OBSCN	ENSG00000154358	0.6388129865355354	[76]	[28,108,NaN]	4	hSpCas9	negative selection	10027199
228216520	228216543	1	+	27869803	HPAFII	viability after 31 days	ATCAGGCTGCGGCTGTGACGTGG	OBSCN	ENSG00000154358	0.826258473480691	[182]	[27,349,NaN]	6	hSpCas9	negative selection	10027200
228217155	228217178	1	+	27869803	HPAFII	viability after 31 days	CGGTGAGCGCTTCTTGCAGGAGG	OBSCN	ENSG00000154358	0.33662657625789283	[182]	[200,51,NaN]	2	hSpCas9	negative selection	10027201
228211912	228211935	1	+	28162770	P31FUJ	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	1.2856648845198708	[36]	[105]	9	hSpCas9	negative selection	10204253
228287713	228287736	1	+	28162770	P31FUJ	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-6.974269190815526	[106]	[0]	-9	hSpCas9	negative selection	10204254
228213460	228213483	1	+	28162770	P31FUJ	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	0.21744998744852306	[343]	[469]	2	hSpCas9	negative selection	10204255
228250164	228250187	1	+	28162770	P31FUJ	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	-0.46818026734530693	[185]	[157]	-4	hSpCas9	negative selection	10204256
228256673	228256696	1	+	28162770	P31FUJ	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-0.25746425864864786	[117]	[115]	-2	hSpCas9	negative selection	10204257
228282099	228282122	1	+	28162770	P31FUJ	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	0.5922943000304924	[253]	[449]	6	hSpCas9	negative selection	10204258
228211912	228211935	1	+	28162770	TF1	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10373619
228287713	228287736	1	+	28162770	TF1	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10373620
228213460	228213483	1	+	28162770	TF1	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	NaN	[NaN]	[174]	1	hSpCas9	negative selection	10373621
228250164	228250187	1	+	28162770	TF1	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10373622
228256673	228256696	1	+	28162770	TF1	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10373623
228282099	228282122	1	+	28162770	TF1	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	NaN	[NaN]	[218]	1	hSpCas9	negative selection	10373624
228211912	228211935	1	+	28162770	SKM1	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	-0.4069641987431618	[17]	[23]	-3	hSpCas9	negative selection	10542985
228287713	228287736	1	+	28162770	SKM1	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-5.069929211465591	[18]	[0]	-9	hSpCas9	negative selection	10542986
228213460	228213483	1	+	28162770	SKM1	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	-0.012432354898959441	[92]	[162]	0	hSpCas9	negative selection	10542987
228250164	228250187	1	+	28162770	SKM1	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	-0.2914869813232256	[35]	[51]	-2	hSpCas9	negative selection	10542988
228256673	228256696	1	+	28162770	SKM1	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-1.6844981742720708	[39]	[21]	-8	hSpCas9	negative selection	10542989
228282099	228282122	1	+	28162770	SKM1	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	-0.30742852519224734	[62]	[89]	-3	hSpCas9	negative selection	10542990
228211912	228211935	1	+	28162770	SKM1	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	-0.4069641987431618	[17]	[23]	-3	hSpCas9	negative selection	10712351
228287713	228287736	1	+	28162770	SKM1	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-5.069929211465591	[18]	[0]	-9	hSpCas9	negative selection	10712352
228213460	228213483	1	+	28162770	SKM1	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	-0.012432354898959441	[92]	[162]	0	hSpCas9	negative selection	10712353
228250164	228250187	1	+	28162770	SKM1	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	-0.2914869813232256	[35]	[51]	-2	hSpCas9	negative selection	10712354
228256673	228256696	1	+	28162770	SKM1	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-1.6844981742720708	[39]	[21]	-8	hSpCas9	negative selection	10712355
228282099	228282122	1	+	28162770	SKM1	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	-0.30742852519224734	[62]	[89]	-3	hSpCas9	negative selection	10712356
228211912	228211935	1	+	28162770	PL21	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	-3.929143402455647	[34]	[0]	-9	hSpCas9	negative selection	10881717
228287713	228287736	1	+	28162770	PL21	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-0.9083848422888487	[68]	[15]	-6	hSpCas9	negative selection	10881718
228213460	228213483	1	+	28162770	PL21	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	-0.6442095150504855	[315]	[87]	-4	hSpCas9	negative selection	10881719
228250164	228250187	1	+	28162770	PL21	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	0.5524413584202011	[140]	[89]	5	hSpCas9	negative selection	10881720
228256673	228256696	1	+	28162770	PL21	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-0.6238300214191804	[130]	[36]	-4	hSpCas9	negative selection	10881721
228282099	228282122	1	+	28162770	PL21	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	0.07615089721386664	[254]	[116]	0	hSpCas9	negative selection	10881722
228211912	228211935	1	+	28162770	P31FUJ	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	1.2856648845198708	[36]	[105]	9	hSpCas9	negative selection	11051083
228287713	228287736	1	+	28162770	P31FUJ	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-6.974269190815526	[106]	[0]	-9	hSpCas9	negative selection	11051084
228213460	228213483	1	+	28162770	P31FUJ	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	0.21744998744852306	[343]	[469]	2	hSpCas9	negative selection	11051085
228250164	228250187	1	+	28162770	P31FUJ	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	-0.46818026734530693	[185]	[157]	-4	hSpCas9	negative selection	11051086
228256673	228256696	1	+	28162770	P31FUJ	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-0.25746425864864786	[117]	[115]	-2	hSpCas9	negative selection	11051087
228282099	228282122	1	+	28162770	P31FUJ	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	0.5922943000304924	[253]	[449]	6	hSpCas9	negative selection	11051088
228211912	228211935	1	+	28162770	OCIAML5	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	-1.7589571664725154	[29]	[15]	-7	hSpCas9	negative selection	11220449
228287713	228287736	1	+	28162770	OCIAML5	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-3.053700432033647	[45]	[9]	-8	hSpCas9	negative selection	11220450
228213460	228213483	1	+	28162770	OCIAML5	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	-0.07445899220044494	[167]	[287]	0	hSpCas9	negative selection	11220451
228250164	228250187	1	+	28162770	OCIAML5	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	-0.4150027652551542	[64]	[87]	-3	hSpCas9	negative selection	11220452
228256673	228256696	1	+	28162770	OCIAML5	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-6.008571056543988	[106]	[2]	-9	hSpCas9	negative selection	11220453
228282099	228282122	1	+	28162770	OCIAML5	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	-0.5694793676088026	[170]	[207]	-4	hSpCas9	negative selection	11220454
228211912	228211935	1	+	28162770	EOL1	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	0.12808116565566685	[65]	[37]	1	hSpCas9	negative selection	11389815
228287713	228287736	1	+	28162770	EOL1	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-5.323379741873051	[75]	[0]	-9	hSpCas9	negative selection	11389816
228213460	228213483	1	+	28162770	EOL1	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	0.26759915802365075	[677]	[429]	2	hSpCas9	negative selection	11389817
228250164	228250187	1	+	28162770	EOL1	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	-0.39159797072282165	[248]	[99]	-3	hSpCas9	negative selection	11389818
228256673	228256696	1	+	28162770	EOL1	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-0.6059669451282452	[207]	[71]	-4	hSpCas9	negative selection	11389819
228282099	228282122	1	+	28162770	EOL1	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	0.660567025892452	[304]	[253]	6	hSpCas9	negative selection	11389820
228211912	228211935	1	+	28162770	MOLM13	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	-1.7372250483600336	[82]	[17]	-7	hSpCas9	negative selection	11559181
228287713	228287736	1	+	28162770	MOLM13	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-1.3960490688793927	[90]	[24]	-6	hSpCas9	negative selection	11559182
228213460	228213483	1	+	28162770	MOLM13	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	-0.08379696430227879	[449]	[306]	0	hSpCas9	negative selection	11559183
228250164	228250187	1	+	28162770	MOLM13	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	0.7511370082678812	[188]	[229]	5	hSpCas9	negative selection	11559184
228256673	228256696	1	+	28162770	MOLM13	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-3.6777880736510564	[176]	[9]	-9	hSpCas9	negative selection	11559185
228282099	228282122	1	+	28162770	MOLM13	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	-0.29110251895162614	[329]	[194]	-2	hSpCas9	negative selection	11559186
228211912	228211935	1	+	28162770	HEL	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	-5.1646160900572475	[55]	[0]	-9	hSpCas9	negative selection	11728547
228287713	228287736	1	+	28162770	HEL	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-3.311457478386518	[61]	[3]	-9	hSpCas9	negative selection	11728548
228213460	228213483	1	+	28162770	HEL	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	1.0221524215484794	[368]	[479]	8	hSpCas9	negative selection	11728549
228250164	228250187	1	+	28162770	HEL	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	0.8099747459150293	[178]	[200]	7	hSpCas9	negative selection	11728550
228256673	228256696	1	+	28162770	HEL	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-1.852025859749221	[123]	[21]	-7	hSpCas9	negative selection	11728551
228282099	228282122	1	+	28162770	HEL	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	0.07589112583880528	[276]	[186]	0	hSpCas9	negative selection	11728552
228211912	228211935	1	+	28162770	MV411	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	-0.716036573192111	[38]	[19]	-5	hSpCas9	negative selection	11897913
228287713	228287736	1	+	28162770	MV411	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-3.840025290467564	[67]	[3]	-9	hSpCas9	negative selection	11897914
228213460	228213483	1	+	28162770	MV411	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	-0.2651488945709009	[310]	[217]	-2	hSpCas9	negative selection	11897915
228250164	228250187	1	+	28162770	MV411	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	0.5045953902798999	[122]	[146]	4	hSpCas9	negative selection	11897916
228256673	228256696	1	+	28162770	MV411	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-1.7525624492172247	[155]	[38]	-8	hSpCas9	negative selection	11897917
228282099	228282122	1	+	28162770	MV411	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	0.12625120426271783	[210]	[193]	1	hSpCas9	negative selection	11897918
228211912	228211935	1	+	28162770	MONOMAC1	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	-0.7819993477807099	[17]	[11]	-6	hSpCas9	negative selection	12067279
228287713	228287736	1	+	28162770	MONOMAC1	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-2.0450337536145033	[53]	[14]	-9	hSpCas9	negative selection	12067280
228213460	228213483	1	+	28162770	MONOMAC1	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	2.0668643025917723	[207]	[998]	9	hSpCas9	negative selection	12067281
228250164	228250187	1	+	28162770	MONOMAC1	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	0.28838998011068817	[94]	[132]	3	hSpCas9	negative selection	12067282
228256673	228256696	1	+	28162770	MONOMAC1	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-1.0645865510359043	[103]	[56]	-7	hSpCas9	negative selection	12067283
228282099	228282122	1	+	28162770	MONOMAC1	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	-0.3306200014381455	[146]	[133]	-3	hSpCas9	negative selection	12067284
228211912	228211935	1	+	28162770	OCIAML2	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	0.455369593314062	[4]	[37]	4	hSpCas9	negative selection	12236645
228287713	228287736	1	+	28162770	OCIAML2	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-5.792557920129523	[9]	[0]	-9	hSpCas9	negative selection	12236646
228213460	228213483	1	+	28162770	OCIAML2	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	0.2115348345043595	[54]	[352]	2	hSpCas9	negative selection	12236647
228250164	228250187	1	+	28162770	OCIAML2	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	0.15230052567801533	[24]	[153]	1	hSpCas9	negative selection	12236648
228256673	228256696	1	+	28162770	OCIAML2	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-2.1266754240248	[25]	[32]	-8	hSpCas9	negative selection	12236649
228282099	228282122	1	+	28162770	OCIAML2	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	-0.221015935170689	[44]	[213]	-2	hSpCas9	negative selection	12236650
228211912	228211935	1	+	28162770	OCIAML3	viability	GGAGAAGGACCAGCAGCCGGTGG	OBSCN	ENSG00000154358	1.0963078605432215	[10]	[70]	8	hSpCas9	negative selection	12406011
228287713	228287736	1	+	28162770	OCIAML3	viability	GGAGGCCCTGAAGGACCTGGAGG	OBSCN	ENSG00000154358	-3.763932641766476	[17]	[3]	-9	hSpCas9	negative selection	12406012
228213460	228213483	1	+	28162770	OCIAML3	viability	AAAGCGGCTGCAAGATCTGGAGG	OBSCN	ENSG00000154358	-0.22203886293720537	[84]	[219]	-2	hSpCas9	negative selection	12406013
228250164	228250187	1	+	28162770	OCIAML3	viability	GGCATGCCAGGCGGACACCGGGG	OBSCN	ENSG00000154358	-0.8757786087395427	[30]	[50]	-6	hSpCas9	negative selection	12406014
228256673	228256696	1	+	28162770	OCIAML3	viability	GGAGCAGCCAGTGCACAGGGAGG	OBSCN	ENSG00000154358	-1.786652718266559	[47]	[41]	-8	hSpCas9	negative selection	12406015
228282099	228282122	1	+	28162770	OCIAML3	viability	GGGCCGAAAATACATCCTGGTGG	OBSCN	ENSG00000154358	0.3457318348583625	[54]	[210]	3	hSpCas9	negative selection	12406016