| 154193545 | 154193568 | X | - | 26472758 | Jiyoye | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 0.2046825176071303 | [83] | [72] | 1 | hSpCas9 | negative selection | 113814 | 154191786 | 154191809 | X | - | 26472758 | Jiyoye | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | -0.04920291315386979 | [117] | [85] | 0 | hSpCas9 | negative selection | 113818 | 154187999 | 154188022 | X | + | 26472758 | Jiyoye | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | -0.7887448284693835 | [125] | [54] | -5 | hSpCas9 | negative selection | 113821 | 154193461 | 154193484 | X | + | 26472758 | Jiyoye | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | -0.35162419811543666 | [576] | [340] | -3 | hSpCas9 | negative selection | 113824 | 154193555 | 154193578 | X | - | 26472758 | Jiyoye | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | -0.9723634365515839 | [280] | [107] | -6 | hSpCas9 | negative selection | 113826 | 154187974 | 154187997 | X | - | 26472758 | Jiyoye | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.32815538230473495 | [393] | [372] | 2 | hSpCas9 | negative selection | 113830 | 154191798 | 154191821 | X | - | 26472758 | Jiyoye | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 0.8000171346705212 | [130] | [171] | 5 | hSpCas9 | negative selection | 113832 | 154190085 | 154190108 | X | + | 26472758 | Jiyoye | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.2581936400360605 | [264] | [238] | 2 | hSpCas9 | negative selection | 113834 | 154190165 | 154190188 | X | - | 26472758 | Jiyoye | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 1.471305718925589 | [76] | [160] | 8 | hSpCas9 | negative selection | 113841 | 154193578 | 154193601 | X | - | 26472758 | Jiyoye | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 0.2551722880608238 | [29] | [26] | 2 | hSpCas9 | negative selection | 113843 | 154193578 | 154193601 | X | - | 26472758 | Jiyoye | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 0.2551722880608238 | [29] | [26] | 2 | hSpCas9 | negative selection | 113848 | 154193545 | 154193568 | X | - | 26472758 | Jiyoye | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 0.2046825176071303 | [83] | [72] | 1 | hSpCas9 | negative selection | 113851 | 154187999 | 154188022 | X | + | 26472758 | Jiyoye | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | -0.7887448284693835 | [125] | [54] | -5 | hSpCas9 | negative selection | 113854 | 154193461 | 154193484 | X | + | 26472758 | Jiyoye | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | -0.35162419811543666 | [576] | [340] | -3 | hSpCas9 | negative selection | 113856 | 154193555 | 154193578 | X | - | 26472758 | Jiyoye | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | -0.9723634365515839 | [280] | [107] | -6 | hSpCas9 | negative selection | 113860 | 154187974 | 154187997 | X | - | 26472758 | Jiyoye | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.32815538230473495 | [393] | [372] | 2 | hSpCas9 | negative selection | 113862 | 154191798 | 154191821 | X | - | 26472758 | Jiyoye | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 0.8000171346705212 | [130] | [171] | 5 | hSpCas9 | negative selection | 113865 | 154190085 | 154190108 | X | + | 26472758 | Jiyoye | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.2581936400360605 | [264] | [238] | 2 | hSpCas9 | negative selection | 113868 | 154190165 | 154190188 | X | - | 26472758 | Jiyoye | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 1.471305718925589 | [76] | [160] | 8 | hSpCas9 | negative selection | 113874 | 154193545 | 154193568 | X | - | 26472758 | KBM7 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 2.0700326526560824 | [243,165] | [505,302] | 9 | hSpCas9 | negative selection | 304932 | 154191786 | 154191809 | X | - | 26472758 | KBM7 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | 0.08428772335872114 | [299,176] | [128,104] | 0 | hSpCas9 | negative selection | 304936 | 154187999 | 154188022 | X | + | 26472758 | KBM7 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | -0.06636852396522824 | [475,361] | [177,193] | 0 | hSpCas9 | negative selection | 304939 | 154193461 | 154193484 | X | + | 26472758 | KBM7 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.13053059480384022 | [2020,1969] | [1006,1051] | 1 | hSpCas9 | negative selection | 304942 | 154193555 | 154193578 | X | - | 26472758 | KBM7 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | -0.16132576215315197 | [488,369] | [227,134] | -1 | hSpCas9 | negative selection | 304944 | 154187974 | 154187997 | X | - | 26472758 | KBM7 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.31622650667061913 | [1931,2037] | [1295,1058] | 3 | hSpCas9 | negative selection | 304948 | 154191798 | 154191821 | X | - | 26472758 | KBM7 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | -0.13477578281448266 | [841,691] | [396,263] | -1 | hSpCas9 | negative selection | 304950 | 154190085 | 154190108 | X | + | 26472758 | KBM7 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | -0.06731123851224541 | [1454,1088] | [419,694] | 0 | hSpCas9 | negative selection | 304952 | 154190165 | 154190188 | X | - | 26472758 | KBM7 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.34932191161536874 | [528,510] | [237,378] | 4 | hSpCas9 | negative selection | 304959 | 154193578 | 154193601 | X | - | 26472758 | KBM7 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 0.7624899690960416 | [180,70] | [86,104] | 8 | hSpCas9 | negative selection | 304961 | 154193578 | 154193601 | X | - | 26472758 | KBM7 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 0.7624899690960416 | [180,70] | [86,104] | 8 | hSpCas9 | negative selection | 304966 | 154193545 | 154193568 | X | - | 26472758 | KBM7 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 2.0700326526560824 | [243,165] | [505,302] | 9 | hSpCas9 | negative selection | 304969 | 154187999 | 154188022 | X | + | 26472758 | KBM7 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | -0.06636852396522824 | [475,361] | [177,193] | 0 | hSpCas9 | negative selection | 304972 | 154193461 | 154193484 | X | + | 26472758 | KBM7 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.13053059480384022 | [2020,1969] | [1006,1051] | 1 | hSpCas9 | negative selection | 304974 | 154193555 | 154193578 | X | - | 26472758 | KBM7 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | -0.16132576215315197 | [488,369] | [227,134] | -1 | hSpCas9 | negative selection | 304978 | 154187974 | 154187997 | X | - | 26472758 | KBM7 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.31622650667061913 | [1931,2037] | [1295,1058] | 3 | hSpCas9 | negative selection | 304980 | 154191798 | 154191821 | X | - | 26472758 | KBM7 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | -0.13477578281448266 | [841,691] | [396,263] | -1 | hSpCas9 | negative selection | 304983 | 154190085 | 154190108 | X | + | 26472758 | KBM7 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | -0.06731123851224541 | [1454,1088] | [419,694] | 0 | hSpCas9 | negative selection | 304986 | 154190165 | 154190188 | X | - | 26472758 | KBM7 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.34932191161536874 | [528,510] | [237,378] | 4 | hSpCas9 | negative selection | 304992 | 154193545 | 154193568 | X | - | 26472758 | Raji | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 0.8405969946786982 | [76] | [31] | 7 | hSpCas9 | negative selection | 496050 | 154191786 | 154191809 | X | - | 26472758 | Raji | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | 0.21047702833770288 | [107] | [28] | 2 | hSpCas9 | negative selection | 496054 | 154187999 | 154188022 | X | + | 26472758 | Raji | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | -0.33513470032735126 | [211] | [38] | -3 | hSpCas9 | negative selection | 496057 | 154193461 | 154193484 | X | + | 26472758 | Raji | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.20512934988579956 | [698] | [186] | 2 | hSpCas9 | negative selection | 496060 | 154193555 | 154193578 | X | - | 26472758 | Raji | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | -0.67397617815106 | [274] | [39] | -5 | hSpCas9 | negative selection | 496062 | 154187974 | 154187997 | X | - | 26472758 | Raji | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.22564641699341914 | [596] | [161] | 2 | hSpCas9 | negative selection | 496066 | 154191798 | 154191821 | X | - | 26472758 | Raji | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | -0.02726599132118246 | [403] | [91] | 0 | hSpCas9 | negative selection | 496068 | 154190085 | 154190108 | X | + | 26472758 | Raji | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | -0.8380313268607977 | [777] | [100] | -6 | hSpCas9 | negative selection | 496070 | 154190165 | 154190188 | X | - | 26472758 | Raji | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.09499981091776691 | [233] | [57] | 0 | hSpCas9 | negative selection | 496077 | 154193578 | 154193601 | X | - | 26472758 | Raji | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 0.33479403147667197 | [40] | [11] | 3 | hSpCas9 | negative selection | 496079 | 154193578 | 154193601 | X | - | 26472758 | Raji | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 0.33479403147667197 | [40] | [11] | 3 | hSpCas9 | negative selection | 496084 | 154193545 | 154193568 | X | - | 26472758 | Raji | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 0.8405969946786982 | [76] | [31] | 7 | hSpCas9 | negative selection | 496087 | 154187999 | 154188022 | X | + | 26472758 | Raji | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | -0.33513470032735126 | [211] | [38] | -3 | hSpCas9 | negative selection | 496090 | 154193461 | 154193484 | X | + | 26472758 | Raji | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.20512934988579956 | [698] | [186] | 2 | hSpCas9 | negative selection | 496092 | 154193555 | 154193578 | X | - | 26472758 | Raji | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | -0.67397617815106 | [274] | [39] | -5 | hSpCas9 | negative selection | 496096 | 154187974 | 154187997 | X | - | 26472758 | Raji | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.22564641699341914 | [596] | [161] | 2 | hSpCas9 | negative selection | 496098 | 154191798 | 154191821 | X | - | 26472758 | Raji | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | -0.02726599132118246 | [403] | [91] | 0 | hSpCas9 | negative selection | 496101 | 154190085 | 154190108 | X | + | 26472758 | Raji | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | -0.8380313268607977 | [777] | [100] | -6 | hSpCas9 | negative selection | 496104 | 154190165 | 154190188 | X | - | 26472758 | Raji | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.09499981091776691 | [233] | [57] | 0 | hSpCas9 | negative selection | 496110 | 154193545 | 154193568 | X | - | 26472758 | K562 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 1.469978428081578 | [129] | [303] | 9 | hSpCas9 | negative selection | 687168 | 154191786 | 154191809 | X | - | 26472758 | K562 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | -1.747543953268135 | [178] | [44] | -7 | hSpCas9 | negative selection | 687172 | 154187999 | 154188022 | X | + | 26472758 | K562 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 0.38002021417200715 | [344] | [378] | 3 | hSpCas9 | negative selection | 687175 | 154193461 | 154193484 | X | + | 26472758 | K562 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.7488742709897396 | [1387] | [1968] | 6 | hSpCas9 | negative selection | 687178 | 154193555 | 154193578 | X | - | 26472758 | K562 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | 1.2533795952380686 | [320] | [645] | 9 | hSpCas9 | negative selection | 687180 | 154187974 | 154187997 | X | - | 26472758 | K562 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.35597865710954446 | [1616] | [1746] | 2 | hSpCas9 | negative selection | 687184 | 154191798 | 154191821 | X | - | 26472758 | K562 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 1.1552521927444208 | [608] | [1144] | 8 | hSpCas9 | negative selection | 687186 | 154190085 | 154190108 | X | + | 26472758 | K562 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.5738754224629252 | [1184] | [1488] | 4 | hSpCas9 | negative selection | 687188 | 154190165 | 154190188 | X | - | 26472758 | K562 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | -0.12921501821562087 | [560] | [432] | -1 | hSpCas9 | negative selection | 687195 | 154193578 | 154193601 | X | - | 26472758 | K562 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 0.5251551352336995 | [134] | [163] | 4 | hSpCas9 | negative selection | 687197 | 154193578 | 154193601 | X | - | 26472758 | K562 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 0.5251551352336995 | [134] | [163] | 4 | hSpCas9 | negative selection | 687202 | 154193545 | 154193568 | X | - | 26472758 | K562 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 1.469978428081578 | [129] | [303] | 9 | hSpCas9 | negative selection | 687205 | 154187999 | 154188022 | X | + | 26472758 | K562 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 0.38002021417200715 | [344] | [378] | 3 | hSpCas9 | negative selection | 687208 | 154193461 | 154193484 | X | + | 26472758 | K562 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.7488742709897396 | [1387] | [1968] | 6 | hSpCas9 | negative selection | 687210 | 154193555 | 154193578 | X | - | 26472758 | K562 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | 1.2533795952380686 | [320] | [645] | 9 | hSpCas9 | negative selection | 687214 | 154187974 | 154187997 | X | - | 26472758 | K562 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.35597865710954446 | [1616] | [1746] | 2 | hSpCas9 | negative selection | 687216 | 154191798 | 154191821 | X | - | 26472758 | K562 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 1.1552521927444208 | [608] | [1144] | 8 | hSpCas9 | negative selection | 687219 | 154190085 | 154190108 | X | + | 26472758 | K562 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.5738754224629252 | [1184] | [1488] | 4 | hSpCas9 | negative selection | 687222 | 154190165 | 154190188 | X | - | 26472758 | K562 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | -0.12921501821562087 | [560] | [432] | -1 | hSpCas9 | negative selection | 687228 | 154187887 | 154187910 | X | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CAGCTTCTTGAACTTCATGGTGG | OPN1MW | ENSG00000268221 | 0.03835630561493952 | [5,6] | [5,4] | 0 | hSpCas9 | positive selection | 3007430 | 154187771 | 154187794 | X | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGTAATTCGGGCCTTCGAAGGGG | OPN1MW | ENSG00000268221 | -0.18533298311233243 | [5,5] | [4,2] | -3 | hSpCas9 | positive selection | 3007431 | 154190116 | 154190139 | X | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TCAAATCTCACATTGCCAAAGGG | OPN1MW | ENSG00000268221 | 0.32234983569130116 | [5,5] | [5,6] | 6 | hSpCas9 | positive selection | 3007432 | 154187772 | 154187795 | X | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TGGTAATTCGGGCCTTCGAAGGG | OPN1MW | ENSG00000268221 | 0.14506852219492417 | [4,4] | [4,3] | 3 | hSpCas9 | positive selection | 3007433 | 154187887 | 154187910 | X | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CAGCTTCTTGAACTTCATGGTGG | OPN1MW | ENSG00000268221 | 0.16107494541707768 | [5,5] | [5,3] | 3 | hSpCas9 | positive selection | 3075288 | 154187771 | 154187794 | X | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGTAATTCGGGCCTTCGAAGGGG | OPN1MW | ENSG00000268221 | -0.03963106436483538 | [5,5] | [5,2] | 0 | hSpCas9 | positive selection | 3075289 | 154190116 | 154190139 | X | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TCAAATCTCACATTGCCAAAGGG | OPN1MW | ENSG00000268221 | 0.10236134900207039 | [5,5] | [4,3] | 1 | hSpCas9 | positive selection | 3075290 | 154187772 | 154187795 | X | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TGGTAATTCGGGCCTTCGAAGGG | OPN1MW | ENSG00000268221 | -0.021450393430048786 | [4,4] | [4,1] | 0 | hSpCas9 | positive selection | 3075291 | 154187887 | 154187910 | X | - | 26780180 | HT29 | viability (Avana library 4 designs) | CAGCTTCTTGAACTTCATGGTGG | OPN1MW | ENSG00000268221 | 0.87981005697699 | [] | [] | 3 | hSpCas9 | negative selection | 3445354 | 154187771 | 154187794 | X | - | 26780180 | HT29 | viability (Avana library 4 designs) | GGTAATTCGGGCCTTCGAAGGGG | OPN1MW | ENSG00000268221 | 0.390171859872629 | [] | [] | 1 | hSpCas9 | negative selection | 3445355 | 154190116 | 154190139 | X | - | 26780180 | HT29 | viability (Avana library 4 designs) | TCAAATCTCACATTGCCAAAGGG | OPN1MW | ENSG00000268221 | -0.916200331706338 | [] | [] | -9 | hSpCas9 | negative selection | 3445356 | 154187772 | 154187795 | X | - | 26780180 | HT29 | viability (Avana library 4 designs) | TGGTAATTCGGGCCTTCGAAGGG | OPN1MW | ENSG00000268221 | 0.509127364667365 | [] | [] | 2 | hSpCas9 | negative selection | 3445357 | 154190116 | 154190139 | X | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TCAAATCTCACATTGCCAAAGGG | OPN1MW | ENSG00000268221 | -1.70437704368354 | [] | [] | -2 | hSpCas9 | negative selection | 3538045 | 154187772 | 154187795 | X | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TGGTAATTCGGGCCTTCGAAGGG | OPN1MW | ENSG00000268221 | 4.64502341714734 | [] | [] | 7 | hSpCas9 | negative selection | 3538046 | 154187771 | 154187794 | X | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGTAATTCGGGCCTTCGAAGGGG | OPN1MW | ENSG00000268221 | 1.76420392799825 | [] | [] | 2 | hSpCas9 | negative selection | 3538047 | 154187887 | 154187910 | X | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CAGCTTCTTGAACTTCATGGTGG | OPN1MW | ENSG00000268221 | -2.40842644675824 | [] | [] | -3 | hSpCas9 | negative selection | 3538048 | 154187788 | 154187811 | X | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ATTACCACATCGCTCCCAGATGG | OPN1MW | ENSG00000268221 | -2.49241921238701 | [] | [] | -3 | hSpCas9 | negative selection | 3538049 | 154182716 | 154182739 | X | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCATCCGCAGGACAGCTATGAGG | OPN1MW | ENSG00000268221 | 6.55425293576277 | [] | [] | 9 | hSpCas9 | negative selection | 3538050 | 154190116 | 154190139 | X | - | 26780180 | A375 | viability (Avana lentiGuide) | TCAAATCTCACATTGCCAAAGGG | OPN1MW | ENSG00000268221 | -8.72671219092 | [] | [] | -9 | hSpCas9 | negative selection | 3646704 | 154187772 | 154187795 | X | - | 26780180 | A375 | viability (Avana lentiGuide) | TGGTAATTCGGGCCTTCGAAGGG | OPN1MW | ENSG00000268221 | -1.60387665252114 | [] | [] | -3 | hSpCas9 | negative selection | 3646705 | 154187771 | 154187794 | X | - | 26780180 | A375 | viability (Avana lentiGuide) | GGTAATTCGGGCCTTCGAAGGGG | OPN1MW | ENSG00000268221 | 1.2257912539628 | [] | [] | 1 | hSpCas9 | negative selection | 3646706 | 154187887 | 154187910 | X | - | 26780180 | A375 | viability (Avana lentiGuide) | CAGCTTCTTGAACTTCATGGTGG | OPN1MW | ENSG00000268221 | -0.673199173992031 | [] | [] | -1 | hSpCas9 | negative selection | 3646707 | 154187788 | 154187811 | X | + | 26780180 | A375 | viability (Avana lentiGuide) | ATTACCACATCGCTCCCAGATGG | OPN1MW | ENSG00000268221 | -1.43220525072422 | [] | [] | -2 | hSpCas9 | negative selection | 3646708 | 154182716 | 154182739 | X | + | 26780180 | A375 | viability (Avana lentiGuide) | CCATCCGCAGGACAGCTATGAGG | OPN1MW | ENSG00000268221 | -2.88294863097259 | [] | [] | -5 | hSpCas9 | negative selection | 3646709 | 154190116 | 154190139 | X | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TCAAATCTCACATTGCCAAAGGG | OPN1MW | ENSG00000268221 | -0.19943649980273917 | [7] | [6,5] | -3 | hSpCas9 | positive selection | 3755363 | 154187772 | 154187795 | X | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TGGTAATTCGGGCCTTCGAAGGG | OPN1MW | ENSG00000268221 | 0.15344550275262592 | [6] | [7,6] | 4 | hSpCas9 | positive selection | 3755364 | 154187771 | 154187794 | X | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGTAATTCGGGCCTTCGAAGGGG | OPN1MW | ENSG00000268221 | 0.06157378058282914 | [6] | [7,6] | 1 | hSpCas9 | positive selection | 3755365 | 154187887 | 154187910 | X | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CAGCTTCTTGAACTTCATGGTGG | OPN1MW | ENSG00000268221 | -0.23804225639484528 | [6] | [6,4] | -4 | hSpCas9 | positive selection | 3755366 | 154187788 | 154187811 | X | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ATTACCACATCGCTCCCAGATGG | OPN1MW | ENSG00000268221 | -0.03105511140720607 | [7] | [7,6] | 0 | hSpCas9 | positive selection | 3755367 | 154182716 | 154182739 | X | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCATCCGCAGGACAGCTATGAGG | OPN1MW | ENSG00000268221 | 0.40051808089056196 | [5] | [7,7] | 9 | hSpCas9 | positive selection | 3755368 | 154190116 | 154190139 | X | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TCAAATCTCACATTGCCAAAGGG | OPN1MW | ENSG00000268221 | 0.3938678044434573 | [7] | [8,7] | 9 | hSpCas9 | positive selection | 3863970 | 154187772 | 154187795 | X | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TGGTAATTCGGGCCTTCGAAGGG | OPN1MW | ENSG00000268221 | 0.12441240889999439 | [6] | [7,4] | 3 | hSpCas9 | positive selection | 3863971 | 154187771 | 154187794 | X | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGTAATTCGGGCCTTCGAAGGGG | OPN1MW | ENSG00000268221 | 0.21467100551069435 | [7] | [6,7] | 5 | hSpCas9 | positive selection | 3863972 | 154187887 | 154187910 | X | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CAGCTTCTTGAACTTCATGGTGG | OPN1MW | ENSG00000268221 | 0.17393016404230333 | [7] | [7,7] | 4 | hSpCas9 | positive selection | 3863973 | 154187788 | 154187811 | X | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ATTACCACATCGCTCCCAGATGG | OPN1MW | ENSG00000268221 | 0.20421861794490637 | [7] | [7,7] | 5 | hSpCas9 | positive selection | 3863974 | 154182716 | 154182739 | X | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCATCCGCAGGACAGCTATGAGG | OPN1MW | ENSG00000268221 | 0.33838721100404817 | [6] | [7,6] | 8 | hSpCas9 | positive selection | 3863975 | 154182790 | 154182813 | X | + | 27661255 | K562 | viability | GTGAGCCAGCAGGCCCGTGGAGG | OPN1MW | ENSG00000268221 | -0.028735753204746972 | [909,852] | [838,564] | -1 | dCas9-KRAB | negative selection | 5498410 | 154183059 | 154183082 | X | - | 27661255 | K562 | viability | GCAGTGAACACACTCATCTACGG | OPN1MW | ENSG00000268221 | 0.1540738554150014 | [4897,5659] | [5113,4309] | 5 | dCas9-KRAB | negative selection | 5498416 | 154183092 | 154183115 | X | - | 27661255 | K562 | viability | GAGGGACTCCGTGGAATGAGAGG | OPN1MW | ENSG00000268221 | 0.13678883766119587 | [1800,2302] | [1973,1640] | 5 | dCas9-KRAB | negative selection | 5498419 | 154182621 | 154182644 | X | + | 27661255 | K562 | viability | GACCCTCAGGTGACGCACCAGGG | OPN1MW | ENSG00000268221 | 0.149134884852121 | [1637,1677] | [1528,1415] | 5 | dCas9-KRAB | negative selection | 5498423 | 154182617 | 154182640 | X | - | 27661255 | K562 | viability | GGTGCGTCACCTGAGGGTCACGG | OPN1MW | ENSG00000268221 | 0.24400777930593043 | [1345,1521] | [1460,1261] | 7 | dCas9-KRAB | negative selection | 5498424 | 154182623 | 154182646 | X | - | 27661255 | K562 | viability | GGCCCTGGTGCGTCACCTGAGGG | OPN1MW | ENSG00000268221 | 0.11524914909954198 | [1920,1919] | [1726,1605] | 4 | dCas9-KRAB | negative selection | 5498427 | 154182676 | 154182699 | X | - | 27661255 | K562 | viability | GAGGCTCCACTGCTGGGCCATGG | OPN1MW | ENSG00000268221 | -0.06260709532866904 | [933,1035] | [866,653] | -2 | dCas9-KRAB | negative selection | 5498430 | 154183059 | 154183082 | X | - | 27661255 | K562 | viability | GCAGTGAACACACTCATCTACGG | OPN1MW | ENSG00000268221 | 0.1540738554150014 | [4897,5659] | [5113,4309] | 5 | dCas9-KRAB | negative selection | 5498437 | 154183092 | 154183115 | X | - | 27661255 | K562 | viability | GAGGGACTCCGTGGAATGAGAGG | OPN1MW | ENSG00000268221 | 0.13678883766119587 | [1800,2302] | [1973,1640] | 5 | dCas9-KRAB | negative selection | 5498438 | 154182621 | 154182644 | X | + | 27661255 | K562 | viability | GACCCTCAGGTGACGCACCAGGG | OPN1MW | ENSG00000268221 | 0.149134884852121 | [1637,1677] | [1528,1415] | 5 | dCas9-KRAB | negative selection | 5498442 | 154182617 | 154182640 | X | - | 27661255 | K562 | viability | GGTGCGTCACCTGAGGGTCACGG | OPN1MW | ENSG00000268221 | 0.24400777930593043 | [1345,1521] | [1460,1261] | 7 | dCas9-KRAB | negative selection | 5498446 | 154182623 | 154182646 | X | - | 27661255 | K562 | viability | GGCCCTGGTGCGTCACCTGAGGG | OPN1MW | ENSG00000268221 | 0.11524914909954198 | [1920,1919] | [1726,1605] | 4 | dCas9-KRAB | negative selection | 5498450 | 154182676 | 154182699 | X | - | 27661255 | K562 | viability | GAGGCTCCACTGCTGGGCCATGG | OPN1MW | ENSG00000268221 | -0.06260709532866904 | [933,1035] | [866,653] | -2 | dCas9-KRAB | negative selection | 5498452 | 154183059 | 154183082 | X | - | 27661255 | K562 | viability | GCAGTGAACACACTCATCTACGG | OPN1MW | ENSG00000268221 | 0.1540738554150014 | [4897,5659] | [5113,4309] | 5 | dCas9-KRAB | negative selection | 5498455 | 154183092 | 154183115 | X | - | 27661255 | K562 | viability | GAGGGACTCCGTGGAATGAGAGG | OPN1MW | ENSG00000268221 | 0.13678883766119587 | [1800,2302] | [1973,1640] | 5 | dCas9-KRAB | negative selection | 5498460 | 154193545 | 154193568 | X | - | 28162770 | P31FUJ | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | -0.7759445294409077 | [101] | [69] | -6 | hSpCas9 | negative selection | 10204837 | 154191786 | 154191809 | X | - | 28162770 | P31FUJ | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | 0.2055221474003811 | [168] | [228] | 2 | hSpCas9 | negative selection | 10204838 | 154187999 | 154188022 | X | + | 28162770 | P31FUJ | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 0.8763195179657339 | [139] | [301] | 8 | hSpCas9 | negative selection | 10204839 | 154193461 | 154193484 | X | + | 28162770 | P31FUJ | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | -0.1284069924763822 | [572] | [615] | -1 | hSpCas9 | negative selection | 10204840 | 154193555 | 154193578 | X | - | 28162770 | P31FUJ | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | 0.8046725010042841 | [132] | [272] | 8 | hSpCas9 | negative selection | 10204841 | 154187974 | 154187997 | X | - | 28162770 | P31FUJ | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.6749392877336331 | [451] | [847] | 7 | hSpCas9 | negative selection | 10204842 | 154191798 | 154191821 | X | - | 28162770 | P31FUJ | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 0.5433444171208934 | [246] | [422] | 6 | hSpCas9 | negative selection | 10204843 | 154190085 | 154190108 | X | + | 28162770 | P31FUJ | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.46267008154866107 | [648] | [1050] | 5 | hSpCas9 | negative selection | 10204844 | 154190165 | 154190188 | X | - | 28162770 | P31FUJ | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.31821296438344004 | [257] | [377] | 3 | hSpCas9 | negative selection | 10204845 | 154193578 | 154193601 | X | - | 28162770 | P31FUJ | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 1.3274982420725085 | [58] | [173] | 9 | hSpCas9 | negative selection | 10204846 | 154193545 | 154193568 | X | - | 28162770 | TF1 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | NaN | [NaN] | [64] | 1 | hSpCas9 | negative selection | 10374203 | 154191786 | 154191809 | X | - | 28162770 | TF1 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | NaN | [NaN] | [123] | 1 | hSpCas9 | negative selection | 10374204 | 154187999 | 154188022 | X | + | 28162770 | TF1 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | NaN | [NaN] | [264] | 1 | hSpCas9 | negative selection | 10374205 | 154193461 | 154193484 | X | + | 28162770 | TF1 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | NaN | [NaN] | [571] | 1 | hSpCas9 | negative selection | 10374206 | 154193555 | 154193578 | X | - | 28162770 | TF1 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | NaN | [NaN] | [183] | 1 | hSpCas9 | negative selection | 10374207 | 154187974 | 154187997 | X | - | 28162770 | TF1 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | NaN | [NaN] | [281] | 1 | hSpCas9 | negative selection | 10374208 | 154191798 | 154191821 | X | - | 28162770 | TF1 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | NaN | [NaN] | [376] | 1 | hSpCas9 | negative selection | 10374209 | 154190085 | 154190108 | X | + | 28162770 | TF1 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | NaN | [NaN] | [574] | 1 | hSpCas9 | negative selection | 10374210 | 154190165 | 154190188 | X | - | 28162770 | TF1 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | NaN | [NaN] | [328] | 1 | hSpCas9 | negative selection | 10374211 | 154193578 | 154193601 | X | - | 28162770 | TF1 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | NaN | [NaN] | [67] | 1 | hSpCas9 | negative selection | 10374212 | 154193545 | 154193568 | X | - | 28162770 | SKM1 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 1.4999263968653567 | [17] | [89] | 9 | hSpCas9 | negative selection | 10543569 | 154191786 | 154191809 | X | - | 28162770 | SKM1 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | -0.6051903089488572 | [36] | [42] | -5 | hSpCas9 | negative selection | 10543570 | 154187999 | 154188022 | X | + | 28162770 | SKM1 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 0.6827904540151674 | [36] | [104] | 6 | hSpCas9 | negative selection | 10543571 | 154193461 | 154193484 | X | + | 28162770 | SKM1 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.09383785431399594 | [149] | [282] | 0 | hSpCas9 | negative selection | 10543572 | 154193555 | 154193578 | X | - | 28162770 | SKM1 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | 0.6953975188865161 | [50] | [145] | 6 | hSpCas9 | negative selection | 10543573 | 154187974 | 154187997 | X | - | 28162770 | SKM1 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.2974335329666138 | [167] | [364] | 3 | hSpCas9 | negative selection | 10543574 | 154191798 | 154191821 | X | - | 28162770 | SKM1 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 1.0113484325685433 | [54] | [195] | 8 | hSpCas9 | negative selection | 10543575 | 154190085 | 154190108 | X | + | 28162770 | SKM1 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.2994618144636616 | [147] | [321] | 3 | hSpCas9 | negative selection | 10543576 | 154190165 | 154190188 | X | - | 28162770 | SKM1 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.1534759828439256 | [88] | [174] | 1 | hSpCas9 | negative selection | 10543577 | 154193578 | 154193601 | X | - | 28162770 | SKM1 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 1.0175336297847482 | [18] | [67] | 8 | hSpCas9 | negative selection | 10543578 | 154193545 | 154193568 | X | - | 28162770 | SKM1 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 1.4999263968653567 | [17] | [89] | 9 | hSpCas9 | negative selection | 10712935 | 154191786 | 154191809 | X | - | 28162770 | SKM1 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | -0.6051903089488572 | [36] | [42] | -5 | hSpCas9 | negative selection | 10712936 | 154187999 | 154188022 | X | + | 28162770 | SKM1 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 0.6827904540151674 | [36] | [104] | 6 | hSpCas9 | negative selection | 10712937 | 154193461 | 154193484 | X | + | 28162770 | SKM1 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.09383785431399594 | [149] | [282] | 0 | hSpCas9 | negative selection | 10712938 | 154193555 | 154193578 | X | - | 28162770 | SKM1 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | 0.6953975188865161 | [50] | [145] | 6 | hSpCas9 | negative selection | 10712939 | 154187974 | 154187997 | X | - | 28162770 | SKM1 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.2974335329666138 | [167] | [364] | 3 | hSpCas9 | negative selection | 10712940 | 154191798 | 154191821 | X | - | 28162770 | SKM1 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 1.0113484325685433 | [54] | [195] | 8 | hSpCas9 | negative selection | 10712941 | 154190085 | 154190108 | X | + | 28162770 | SKM1 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.2994618144636616 | [147] | [321] | 3 | hSpCas9 | negative selection | 10712942 | 154190165 | 154190188 | X | - | 28162770 | SKM1 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.1534759828439256 | [88] | [174] | 1 | hSpCas9 | negative selection | 10712943 | 154193578 | 154193601 | X | - | 28162770 | SKM1 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 1.0175336297847482 | [18] | [67] | 8 | hSpCas9 | negative selection | 10712944 | 154193545 | 154193568 | X | - | 28162770 | PL21 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | -1.8273411219327866 | [105] | [12] | -8 | hSpCas9 | negative selection | 10882301 | 154191786 | 154191809 | X | - | 28162770 | PL21 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | -0.43457592142893553 | [117] | [37] | -3 | hSpCas9 | negative selection | 10882302 | 154187999 | 154188022 | X | + | 28162770 | PL21 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | -0.536825979676886 | [149] | [44] | -4 | hSpCas9 | negative selection | 10882303 | 154193461 | 154193484 | X | + | 28162770 | PL21 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | -0.9291434024556465 | [559] | [127] | -6 | hSpCas9 | negative selection | 10882304 | 154193555 | 154193578 | X | - | 28162770 | PL21 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | 1.5287623619506907 | [128] | [161] | 9 | hSpCas9 | negative selection | 10882305 | 154187974 | 154187997 | X | - | 28162770 | PL21 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | -0.34593387283824106 | [548] | [187] | -2 | hSpCas9 | negative selection | 10882306 | 154191798 | 154191821 | X | - | 28162770 | PL21 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 0.14569183046694367 | [242] | [116] | 1 | hSpCas9 | negative selection | 10882307 | 154190085 | 154190108 | X | + | 28162770 | PL21 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | -0.26872582130896494 | [536] | [193] | -2 | hSpCas9 | negative selection | 10882308 | 154190165 | 154190188 | X | - | 28162770 | PL21 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | -0.33661379318921625 | [205] | [70] | -2 | hSpCas9 | negative selection | 10882309 | 154193578 | 154193601 | X | - | 28162770 | PL21 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 1.0652100344032116 | [55] | [50] | 8 | hSpCas9 | negative selection | 10882310 | 154193545 | 154193568 | X | - | 28162770 | P31FUJ | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | -0.7759445294409077 | [101] | [69] | -6 | hSpCas9 | negative selection | 11051667 | 154191786 | 154191809 | X | - | 28162770 | P31FUJ | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | 0.2055221474003811 | [168] | [228] | 2 | hSpCas9 | negative selection | 11051668 | 154187999 | 154188022 | X | + | 28162770 | P31FUJ | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 0.8763195179657339 | [139] | [301] | 8 | hSpCas9 | negative selection | 11051669 | 154193461 | 154193484 | X | + | 28162770 | P31FUJ | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | -0.1284069924763822 | [572] | [615] | -1 | hSpCas9 | negative selection | 11051670 | 154193555 | 154193578 | X | - | 28162770 | P31FUJ | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | 0.8046725010042841 | [132] | [272] | 8 | hSpCas9 | negative selection | 11051671 | 154187974 | 154187997 | X | - | 28162770 | P31FUJ | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.6749392877336331 | [451] | [847] | 7 | hSpCas9 | negative selection | 11051672 | 154191798 | 154191821 | X | - | 28162770 | P31FUJ | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 0.5433444171208934 | [246] | [422] | 6 | hSpCas9 | negative selection | 11051673 | 154190085 | 154190108 | X | + | 28162770 | P31FUJ | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.46267008154866107 | [648] | [1050] | 5 | hSpCas9 | negative selection | 11051674 | 154190165 | 154190188 | X | - | 28162770 | P31FUJ | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.31821296438344004 | [257] | [377] | 3 | hSpCas9 | negative selection | 11051675 | 154193578 | 154193601 | X | - | 28162770 | P31FUJ | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 1.3274982420725085 | [58] | [173] | 9 | hSpCas9 | negative selection | 11051676 | 154193545 | 154193568 | X | - | 28162770 | OCIAML5 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 1.215678035771837 | [51] | [217] | 9 | hSpCas9 | negative selection | 11221033 | 154191786 | 154191809 | X | - | 28162770 | OCIAML5 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | -0.3864029985151852 | [83] | [115] | -3 | hSpCas9 | negative selection | 11221034 | 154187999 | 154188022 | X | + | 28162770 | OCIAML5 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 0.6401387889373067 | [90] | [255] | 5 | hSpCas9 | negative selection | 11221035 | 154193461 | 154193484 | X | + | 28162770 | OCIAML5 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.8296935212787548 | [292] | [939] | 7 | hSpCas9 | negative selection | 11221036 | 154193555 | 154193578 | X | - | 28162770 | OCIAML5 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | 1.2522700889507385 | [49] | [214] | 9 | hSpCas9 | negative selection | 11221037 | 154187974 | 154187997 | X | - | 28162770 | OCIAML5 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.14793342913600305 | [373] | [747] | 1 | hSpCas9 | negative selection | 11221038 | 154191798 | 154191821 | X | - | 28162770 | OCIAML5 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 1.268721651915514 | [145] | [634] | 9 | hSpCas9 | negative selection | 11221039 | 154190085 | 154190108 | X | + | 28162770 | OCIAML5 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.4326337285900541 | [368] | [898] | 4 | hSpCas9 | negative selection | 11221040 | 154190165 | 154190188 | X | - | 28162770 | OCIAML5 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.30816937440988157 | [165] | [370] | 2 | hSpCas9 | negative selection | 11221041 | 154193578 | 154193601 | X | - | 28162770 | OCIAML5 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 2.0451738547108023 | [19] | [148] | 9 | hSpCas9 | negative selection | 11221042 | 154193545 | 154193568 | X | - | 28162770 | EOL1 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 1.3582009490167253 | [153] | [207] | 9 | hSpCas9 | negative selection | 11390399 | 154191786 | 154191809 | X | - | 28162770 | EOL1 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | -0.74171483125247 | [145] | [45] | -5 | hSpCas9 | negative selection | 11390400 | 154187999 | 154188022 | X | + | 28162770 | EOL1 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 1.0691874766020981 | [274] | [303] | 8 | hSpCas9 | negative selection | 11390401 | 154193461 | 154193484 | X | + | 28162770 | EOL1 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.048217625977878376 | [904] | [492] | 0 | hSpCas9 | negative selection | 11390402 | 154193555 | 154193578 | X | - | 28162770 | EOL1 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | -0.21435033425115346 | [206] | [93] | -2 | hSpCas9 | negative selection | 11390403 | 154187974 | 154187997 | X | - | 28162770 | EOL1 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.2949162215156498 | [983] | [635] | 2 | hSpCas9 | negative selection | 11390404 | 154191798 | 154191821 | X | - | 28162770 | EOL1 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 0.3959477134684909 | [250] | [173] | 3 | hSpCas9 | negative selection | 11390405 | 154190085 | 154190108 | X | + | 28162770 | EOL1 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.06868874724261409 | [551] | [304] | 0 | hSpCas9 | negative selection | 11390406 | 154190165 | 154190188 | X | - | 28162770 | EOL1 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.5485321611208747 | [230] | [177] | 5 | hSpCas9 | negative selection | 11390407 | 154193578 | 154193601 | X | - | 28162770 | EOL1 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 1.1783043638163173 | [77] | [92] | 8 | hSpCas9 | negative selection | 11390408 | 154193545 | 154193568 | X | - | 28162770 | MOLM13 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 1.421719200111653 | [126] | [245] | 9 | hSpCas9 | negative selection | 11559765 | 154191786 | 154191809 | X | - | 28162770 | MOLM13 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | 1.636395105901557 | [112] | [253] | 9 | hSpCas9 | negative selection | 11559766 | 154187999 | 154188022 | X | + | 28162770 | MOLM13 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 0.48674840879589465 | [227] | [230] | 3 | hSpCas9 | negative selection | 11559767 | 154193461 | 154193484 | X | + | 28162770 | MOLM13 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 1.207032629016155 | [661] | [1104] | 8 | hSpCas9 | negative selection | 11559768 | 154193555 | 154193578 | X | - | 28162770 | MOLM13 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | 0.5736840455671756 | [183] | [197] | 4 | hSpCas9 | negative selection | 11559769 | 154187974 | 154187997 | X | - | 28162770 | MOLM13 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.7786481687138298 | [777] | [964] | 6 | hSpCas9 | negative selection | 11559770 | 154191798 | 154191821 | X | - | 28162770 | MOLM13 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 0.6592223220241838 | [274] | [313] | 5 | hSpCas9 | negative selection | 11559771 | 154190085 | 154190108 | X | + | 28162770 | MOLM13 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.07302976420336549 | [709] | [539] | 0 | hSpCas9 | negative selection | 11559772 | 154190165 | 154190188 | X | - | 28162770 | MOLM13 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.14064748676074867 | [339] | [270] | 1 | hSpCas9 | negative selection | 11559773 | 154193578 | 154193601 | X | - | 28162770 | MOLM13 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | -1.1983732212784253 | [72] | [22] | -6 | hSpCas9 | negative selection | 11559774 | 154193545 | 154193568 | X | - | 28162770 | HEL | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 1.8788061902338815 | [89] | [211] | 9 | hSpCas9 | negative selection | 11729131 | 154191786 | 154191809 | X | - | 28162770 | HEL | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | 1.0577763312792008 | [125] | [167] | 8 | hSpCas9 | negative selection | 11729132 | 154187999 | 154188022 | X | + | 28162770 | HEL | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 1.6049367992879726 | [173] | [338] | 9 | hSpCas9 | negative selection | 11729133 | 154193461 | 154193484 | X | + | 28162770 | HEL | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.7655512376045497 | [663] | [722] | 6 | hSpCas9 | negative selection | 11729134 | 154193555 | 154193578 | X | - | 28162770 | HEL | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | -0.07242239184750071 | [196] | [119] | 0 | hSpCas9 | negative selection | 11729135 | 154187974 | 154187997 | X | - | 28162770 | HEL | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 1.098049229932836 | [732] | [1004] | 8 | hSpCas9 | negative selection | 11729136 | 154191798 | 154191821 | X | - | 28162770 | HEL | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 0.21327426208623332 | [267] | [198] | 1 | hSpCas9 | negative selection | 11729137 | 154190085 | 154190108 | X | + | 28162770 | HEL | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.32473288282063084 | [550] | [441] | 2 | hSpCas9 | negative selection | 11729138 | 154190165 | 154190188 | X | - | 28162770 | HEL | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | -0.611017760245426 | [309] | [129] | -4 | hSpCas9 | negative selection | 11729139 | 154193578 | 154193601 | X | - | 28162770 | HEL | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 0.7193601136032697 | [54] | [57] | 6 | hSpCas9 | negative selection | 11729140 | 154193545 | 154193568 | X | - | 28162770 | MV411 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 0.036870564843116904 | [80] | [69] | 0 | hSpCas9 | negative selection | 11898497 | 154191786 | 154191809 | X | - | 28162770 | MV411 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | 0.7056429092179927 | [106] | [146] | 6 | hSpCas9 | negative selection | 11898498 | 154187999 | 154188022 | X | + | 28162770 | MV411 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 1.421767731345089 | [108] | [245] | 9 | hSpCas9 | negative selection | 11898499 | 154193461 | 154193484 | X | + | 28162770 | MV411 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.8814719714090915 | [394] | [612] | 7 | hSpCas9 | negative selection | 11898500 | 154193555 | 154193578 | X | - | 28162770 | MV411 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | 1.1994575218809536 | [106] | [206] | 9 | hSpCas9 | negative selection | 11898501 | 154187974 | 154187997 | X | - | 28162770 | MV411 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.9529128588211659 | [527] | [860] | 8 | hSpCas9 | negative selection | 11898502 | 154191798 | 154191821 | X | - | 28162770 | MV411 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 0.3976801863633878 | [163] | [181] | 3 | hSpCas9 | negative selection | 11898503 | 154190085 | 154190108 | X | + | 28162770 | MV411 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.21935500881473535 | [414] | [406] | 2 | hSpCas9 | negative selection | 11898504 | 154190165 | 154190188 | X | - | 28162770 | MV411 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.3137107702019412 | [233] | [244] | 2 | hSpCas9 | negative selection | 11898505 | 154193578 | 154193601 | X | - | 28162770 | MV411 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 0.16726720209879176 | [36] | [34] | 1 | hSpCas9 | negative selection | 11898506 | 154193545 | 154193568 | X | - | 28162770 | MONOMAC1 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | -0.021187011660135813 | [53] | [60] | 0 | hSpCas9 | negative selection | 12067863 | 154191786 | 154191809 | X | - | 28162770 | MONOMAC1 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | -0.230203710994753 | [43] | [42] | -2 | hSpCas9 | negative selection | 12067864 | 154187999 | 154188022 | X | + | 28162770 | MONOMAC1 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | -0.25014818351911594 | [82] | [79] | -2 | hSpCas9 | negative selection | 12067865 | 154193461 | 154193484 | X | + | 28162770 | MONOMAC1 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.1269075934263133 | [428] | [536] | 1 | hSpCas9 | negative selection | 12067866 | 154193555 | 154193578 | X | - | 28162770 | MONOMAC1 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | -1.4753380095466582 | [113] | [46] | -8 | hSpCas9 | negative selection | 12067867 | 154187974 | 154187997 | X | - | 28162770 | MONOMAC1 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.5288865763150674 | [340] | [563] | 5 | hSpCas9 | negative selection | 12067868 | 154191798 | 154191821 | X | - | 28162770 | MONOMAC1 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | -0.053779796079321485 | [181] | [200] | 0 | hSpCas9 | negative selection | 12067869 | 154190085 | 154190108 | X | + | 28162770 | MONOMAC1 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.4550398495201393 | [335] | [527] | 4 | hSpCas9 | negative selection | 12067870 | 154190165 | 154190188 | X | - | 28162770 | MONOMAC1 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | -0.5399245605825621 | [155] | [122] | -4 | hSpCas9 | negative selection | 12067871 | 154193578 | 154193601 | X | - | 28162770 | MONOMAC1 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | -1.1970368470595538 | [37] | [18] | -7 | hSpCas9 | negative selection | 12067872 | 154193545 | 154193568 | X | - | 28162770 | OCIAML2 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 0.8416480996114821 | [14] | [148] | 7 | hSpCas9 | negative selection | 12237229 | 154191786 | 154191809 | X | - | 28162770 | OCIAML2 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | 1.278308410590121 | [8] | [120] | 9 | hSpCas9 | negative selection | 12237230 | 154187999 | 154188022 | X | + | 28162770 | OCIAML2 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 0.8892661198442218 | [14] | [153] | 8 | hSpCas9 | negative selection | 12237231 | 154193461 | 154193484 | X | + | 28162770 | OCIAML2 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.8151537059101066 | [96] | [945] | 7 | hSpCas9 | negative selection | 12237232 | 154193555 | 154193578 | X | - | 28162770 | OCIAML2 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | 0.630908201219901 | [23] | [205] | 6 | hSpCas9 | negative selection | 12237233 | 154187974 | 154187997 | X | - | 28162770 | OCIAML2 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.7343016260280644 | [94] | [875] | 7 | hSpCas9 | negative selection | 12237234 | 154191798 | 154191821 | X | - | 28162770 | OCIAML2 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | 0.4589808468664408 | [41] | [319] | 4 | hSpCas9 | negative selection | 12237235 | 154190085 | 154190108 | X | + | 28162770 | OCIAML2 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.023820382573552568 | [73] | [416] | 0 | hSpCas9 | negative selection | 12237236 | 154190165 | 154190188 | X | - | 28162770 | OCIAML2 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | 0.22980989289893097 | [35] | [233] | 2 | hSpCas9 | negative selection | 12237237 | 154193578 | 154193601 | X | - | 28162770 | OCIAML2 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 1.7772976882014242 | [4] | [94] | 9 | hSpCas9 | negative selection | 12237238 | 154193545 | 154193568 | X | - | 28162770 | OCIAML3 | viability | AAGGGTGGAAGGGGTAGCCAGGG | OPN1MW | ENSG00000268221 | 0.6283847810122847 | [20] | [97] | 6 | hSpCas9 | negative selection | 12406595 | 154191786 | 154191809 | X | - | 28162770 | OCIAML3 | viability | GCTGAGTGGGGTGATGCAGCAGG | OPN1MW | ENSG00000268221 | -0.9226303877855339 | [26] | [42] | -6 | hSpCas9 | negative selection | 12406596 | 154187999 | 154188022 | X | + | 28162770 | OCIAML3 | viability | GGTCTATGGCTACTTCGTGCTGG | OPN1MW | ENSG00000268221 | 0.29261056025809423 | [42] | [158] | 2 | hSpCas9 | negative selection | 12406597 | 154193461 | 154193484 | X | + | 28162770 | OCIAML3 | viability | GACGCGCATGGTGGTGGTGATGG | OPN1MW | ENSG00000268221 | 0.7602564366828894 | [149] | [766] | 6 | hSpCas9 | negative selection | 12406598 | 154193555 | 154193578 | X | - | 28162770 | OCIAML3 | viability | GCAGCCATCAAAGGGTGGAAGGG | OPN1MW | ENSG00000268221 | -0.663270302761277 | [31] | [60] | -5 | hSpCas9 | negative selection | 12406599 | 154187974 | 154187997 | X | - | 28162770 | OCIAML3 | viability | GTTCACAACGCTGATAGTGCTGG | OPN1MW | ENSG00000268221 | 0.8606293742295819 | [136] | [750] | 7 | hSpCas9 | negative selection | 12406600 | 154191798 | 154191821 | X | - | 28162770 | OCIAML3 | viability | GAGCACGATGATGCTGAGTGGGG | OPN1MW | ENSG00000268221 | -0.5028597522659678 | [68] | [146] | -4 | hSpCas9 | negative selection | 12406601 | 154190085 | 154190108 | X | + | 28162770 | OCIAML3 | viability | TTCCTGGGAGAGATGGATGGTGG | OPN1MW | ENSG00000268221 | 0.19148784776970174 | [151] | [523] | 1 | hSpCas9 | negative selection | 12406602 | 154190165 | 154190188 | X | - | 28162770 | OCIAML3 | viability | AGCAGCCCAGATCCAGGAGAAGG | OPN1MW | ENSG00000268221 | -0.2633623283356917 | [65] | [165] | -2 | hSpCas9 | negative selection | 12406603 | 154193578 | 154193601 | X | - | 28162770 | OCIAML3 | viability | TTTTGGCAAAGAAGGCCGGCAGG | OPN1MW | ENSG00000268221 | 0.33199177823206005 | [14] | [56] | 3 | hSpCas9 | negative selection | 12406604 |