Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:94233
• Symbol:OPN4
• Description:opsin 4

DataSource: http://genomecrispr.dkfz.de/#!/results/OPN4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
86656192	86656215	10	-	26472758	Jiyoye	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	2.7670713265922564	[14]	[76]	9	hSpCas9	negative selection	113896
86661337	86661360	10	-	26472758	Jiyoye	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	0.2154145788230888	[232]	[203]	1	hSpCas9	negative selection	113897
86654884	86654907	10	+	26472758	Jiyoye	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	0.35502409945476665	[168]	[162]	2	hSpCas9	negative selection	113898
86656229	86656252	10	+	26472758	Jiyoye	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	-0.2688612140180011	[424]	[265]	-2	hSpCas9	negative selection	113899
86658112	86658135	10	-	26472758	Jiyoye	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.4131991691336433	[238]	[239]	3	hSpCas9	negative selection	113900
86658127	86658150	10	+	26472758	Jiyoye	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.134922445642701	[156]	[129]	1	hSpCas9	negative selection	113901
86659337	86659360	10	+	26472758	Jiyoye	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	0.7026312650320448	[109]	[134]	5	hSpCas9	negative selection	113902
86659369	86659392	10	-	26472758	Jiyoye	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-0.2902618484736954	[59]	[36]	-2	hSpCas9	negative selection	113903
86659407	86659430	10	-	26472758	Jiyoye	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	0.11439363227802746	[48]	[39]	0	hSpCas9	negative selection	113904
86660003	86660026	10	-	26472758	Jiyoye	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-1.147413470171764	[187]	[63]	-7	hSpCas9	negative selection	113905
86656192	86656215	10	-	26472758	KBM7	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.34979120409530473	[335,209]	[197,126]	4	hSpCas9	negative selection	305014
86661337	86661360	10	-	26472758	KBM7	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-0.22548216294085943	[1482,1173]	[435,614]	-2	hSpCas9	negative selection	305015
86654884	86654907	10	+	26472758	KBM7	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-0.16755530217389392	[937,610]	[397,247]	-2	hSpCas9	negative selection	305016
86656229	86656252	10	+	26472758	KBM7	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	0.34308226977113576	[1473,787]	[620,688]	3	hSpCas9	negative selection	305017
86658112	86658135	10	-	26472758	KBM7	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.11242859598736099	[832,649]	[364,381]	1	hSpCas9	negative selection	305018
86658127	86658150	10	+	26472758	KBM7	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.44545180597612755	[457,326]	[356,150]	5	hSpCas9	negative selection	305019
86659337	86659360	10	+	26472758	KBM7	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	-0.517630529706063	[673,825]	[191,301]	-4	hSpCas9	negative selection	305020
86659369	86659392	10	-	26472758	KBM7	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	0.14751512867562167	[202,259]	[109,133]	1	hSpCas9	negative selection	305021
86659407	86659430	10	-	26472758	KBM7	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	-0.0696094850794744	[355,236]	[172,92]	0	hSpCas9	negative selection	305022
86660003	86660026	10	-	26472758	KBM7	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	0.33738023398148326	[306,261]	[187,150]	3	hSpCas9	negative selection	305023
86656192	86656215	10	-	26472758	Raji	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.31447976961353596	[148]	[42]	3	hSpCas9	negative selection	496132
86661337	86661360	10	-	26472758	Raji	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-0.9602071591651249	[720]	[85]	-6	hSpCas9	negative selection	496133
86654884	86654907	10	+	26472758	Raji	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	0.4705199327404133	[282]	[90]	4	hSpCas9	negative selection	496134
86656229	86656252	10	+	26472758	Raji	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	0.5224210346524434	[461]	[153]	5	hSpCas9	negative selection	496135
86658112	86658135	10	-	26472758	Raji	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	-0.8542995330752986	[482]	[61]	-6	hSpCas9	negative selection	496136
86658127	86658150	10	+	26472758	Raji	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.4246300853985976	[213]	[36]	-3	hSpCas9	negative selection	496137
86659337	86659360	10	+	26472758	Raji	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	-0.10821332445399529	[352]	[75]	-1	hSpCas9	negative selection	496138
86659369	86659392	10	-	26472758	Raji	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-1.9800793058767399	[67]	[3]	-8	hSpCas9	negative selection	496139
86659407	86659430	10	-	26472758	Raji	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	0.8479969065549501	[78]	[32]	7	hSpCas9	negative selection	496140
86660003	86660026	10	-	26472758	Raji	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.16563495903281655	[144]	[29]	-1	hSpCas9	negative selection	496141
86656192	86656215	10	-	26472758	K562	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.5456582029593215	[165]	[95]	-3	hSpCas9	negative selection	687250
86661337	86661360	10	-	26472758	K562	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-1.0091223922406651	[1029]	[431]	-5	hSpCas9	negative selection	687251
86654884	86654907	10	+	26472758	K562	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-0.4020581622674135	[550]	[351]	-3	hSpCas9	negative selection	687252
86656229	86656252	10	+	26472758	K562	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	0.057013605889567165	[902]	[792]	0	hSpCas9	negative selection	687253
86658112	86658135	10	-	26472758	K562	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.1243791096579977	[738]	[679]	0	hSpCas9	negative selection	687254
86658127	86658150	10	+	26472758	K562	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.23090392119196532	[428]	[424]	1	hSpCas9	negative selection	687255
86659337	86659360	10	+	26472758	K562	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	0.08769322397899382	[475]	[426]	0	hSpCas9	negative selection	687256
86659369	86659392	10	-	26472758	K562	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-0.35824577478816827	[286]	[188]	-2	hSpCas9	negative selection	687257
86659407	86659430	10	-	26472758	K562	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	-0.20072080340181608	[225]	[165]	-1	hSpCas9	negative selection	687258
86660003	86660026	10	-	26472758	K562	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.8322025539364656	[231]	[109]	-5	hSpCas9	negative selection	687259
86654897	86654920	10	-	26627737	DLD1	viability	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	0.0057378916368816535	[278]	[145,78,43]	0	hSpCas9	negative selection	775914
86656208	86656231	10	+	26627737	DLD1	viability	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.8683219556321526	[823]	[126,161,135]	-7	hSpCas9	negative selection	775915
86658074	86658097	10	-	26627737	DLD1	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.2769824286751579	[840]	[321,387,257]	3	hSpCas9	negative selection	775916
86658672	86658695	10	-	26627737	DLD1	viability	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	1.2493050137771746	[372]	[322,348,177]	9	hSpCas9	negative selection	775917
86659356	86659379	10	-	26627737	DLD1	viability	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.26988280758957267	[685]	[190,146,191]	-3	hSpCas9	negative selection	775918
86660050	86660073	10	-	26627737	DLD1	viability	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-0.643895457513445	[1868]	[469,463,215]	-6	hSpCas9	negative selection	775919
86654897	86654920	10	-	26627737	GBM cells	viability after 5 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	0.35659571157302294	[74]	[41,60]	5	hSpCas9	negative selection	858229
86656208	86656231	10	+	26627737	GBM cells	viability after 5 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.7449423148890392	[449]	[121,165]	-8	hSpCas9	negative selection	858230
86658074	86658097	10	-	26627737	GBM cells	viability after 5 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.5750173134467269	[349]	[143,107]	-7	hSpCas9	negative selection	858231
86658672	86658695	10	-	26627737	GBM cells	viability after 5 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.3630990234936178	[302]	[194,222]	5	hSpCas9	negative selection	858232
86659356	86659379	10	-	26627737	GBM cells	viability after 5 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.5652964663748603	[188]	[61,74]	-7	hSpCas9	negative selection	858233
86660050	86660073	10	-	26627737	GBM cells	viability after 5 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-0.8164955759140728	[774]	[226,244]	-8	hSpCas9	negative selection	858234
86654897	86654920	10	-	26627737	GBM cells	viability after 13 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-0.2930292097302567	[74]	[46,21]	-3	hSpCas9	negative selection	940544
86656208	86656231	10	+	26627737	GBM cells	viability after 13 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.893243177128601	[449]	[147,117]	-8	hSpCas9	negative selection	940545
86658074	86658097	10	-	26627737	GBM cells	viability after 13 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.4808653539782931	[349]	[145,127]	-5	hSpCas9	negative selection	940546
86658672	86658695	10	-	26627737	GBM cells	viability after 13 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.3711963441105003	[302]	[253,178]	5	hSpCas9	negative selection	940547
86659356	86659379	10	-	26627737	GBM cells	viability after 13 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.8654154795058144	[188]	[79,36]	-7	hSpCas9	negative selection	940548
86660050	86660073	10	-	26627737	GBM cells	viability after 13 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-1.0580004932679823	[774]	[196,205]	-8	hSpCas9	negative selection	940549
86654897	86654920	10	-	26627737	GBM cells	viability after 21 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-0.836218020891702	[74]	[26,18]	-6	hSpCas9	negative selection	1022859
86656208	86656231	10	+	26627737	GBM cells	viability after 21 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.6955678490826898	[449]	[151,149]	-6	hSpCas9	negative selection	1022860
86658074	86658097	10	-	26627737	GBM cells	viability after 21 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-1.102466899668511	[349]	[98,78]	-7	hSpCas9	negative selection	1022861
86658672	86658695	10	-	26627737	GBM cells	viability after 21 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.1013100762583043	[302]	[197,156]	1	hSpCas9	negative selection	1022862
86659356	86659379	10	-	26627737	GBM cells	viability after 21 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.8838433740024707	[188]	[63,47]	-6	hSpCas9	negative selection	1022863
86660050	86660073	10	-	26627737	GBM cells	viability after 21 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-0.7190094138427259	[774]	[248,261]	-6	hSpCas9	negative selection	1022864
86654897	86654920	10	-	26627737	RPE1	viability after 9 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-2.1024249640251087	[175]	[21,0]	-8	hSpCas9	negative selection	1105174
86656208	86656231	10	+	26627737	RPE1	viability after 9 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-1.5105609955222798	[1253]	[156,112]	-8	hSpCas9	negative selection	1105175
86658074	86658097	10	-	26627737	RPE1	viability after 9 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.2819509702649746	[1258]	[321,326]	-2	hSpCas9	negative selection	1105176
86658672	86658695	10	-	26627737	RPE1	viability after 9 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.19654256102273676	[965]	[315,385]	1	hSpCas9	negative selection	1105177
86659356	86659379	10	-	26627737	RPE1	viability after 9 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-1.4605182368737466	[585]	[22,122]	-8	hSpCas9	negative selection	1105178
86660050	86660073	10	-	26627737	RPE1	viability after 9 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-0.2793188689717636	[2298]	[589,596]	-2	hSpCas9	negative selection	1105179
86654897	86654920	10	-	26627737	RPE1	viability after 12 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-4.992163505768033	[175]	[0,1]	-9	hSpCas9	negative selection	1187489
86656208	86656231	10	+	26627737	RPE1	viability after 12 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.9860920590457553	[1253]	[240,94]	-6	hSpCas9	negative selection	1187490
86658074	86658097	10	-	26627737	RPE1	viability after 12 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.07320322813735392	[1258]	[401,306]	0	hSpCas9	negative selection	1187491
86658672	86658695	10	-	26627737	RPE1	viability after 12 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.33790970228205003	[965]	[379,272]	2	hSpCas9	negative selection	1187492
86659356	86659379	10	-	26627737	RPE1	viability after 12 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-1.154715649839742	[585]	[77,62]	-7	hSpCas9	negative selection	1187493
86660050	86660073	10	-	26627737	RPE1	viability after 12 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-0.374563215030699	[2298]	[490,460]	-3	hSpCas9	negative selection	1187494
86654897	86654920	10	-	26627737	RPE1	viability after 15 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-2.2219314186272374	[175]	[0,19]	-8	hSpCas9	negative selection	1269804
86656208	86656231	10	+	26627737	RPE1	viability after 15 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-1.6908162709775898	[1253]	[172,48]	-8	hSpCas9	negative selection	1269805
86658074	86658097	10	-	26627737	RPE1	viability after 15 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.7395368129437281	[1258]	[167,256]	-5	hSpCas9	negative selection	1269806
86658672	86658695	10	-	26627737	RPE1	viability after 15 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.4741609639299991	[965]	[458,302]	3	hSpCas9	negative selection	1269807
86659356	86659379	10	-	26627737	RPE1	viability after 15 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-1.3779123310213712	[585]	[75,51]	-7	hSpCas9	negative selection	1269808
86660050	86660073	10	-	26627737	RPE1	viability after 15 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-0.6307419599402897	[2298]	[390,447]	-4	hSpCas9	negative selection	1269809
86654897	86654920	10	-	26627737	RPE1	viability after 18 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-5.569763358536554	[175]	[0,0]	-9	hSpCas9	negative selection	1352119
86656208	86656231	10	+	26627737	RPE1	viability after 18 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-1.3642804402056483	[1253]	[129,132]	-7	hSpCas9	negative selection	1352120
86658074	86658097	10	-	26627737	RPE1	viability after 18 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.14300700787232712	[1258]	[400,207]	-1	hSpCas9	negative selection	1352121
86658672	86658695	10	-	26627737	RPE1	viability after 18 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.26860559377466736	[965]	[358,265]	1	hSpCas9	negative selection	1352122
86659356	86659379	10	-	26627737	RPE1	viability after 18 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-1.0339575180628024	[585]	[83,69]	-6	hSpCas9	negative selection	1352123
86660050	86660073	10	-	26627737	RPE1	viability after 18 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-0.34407517170945323	[2298]	[394,588]	-2	hSpCas9	negative selection	1352124
86654897	86654920	10	-	26627737	HeLa	viability after 8 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	0.6893483612743395	[217]	[95,280,74]	6	hSpCas9	negative selection	1434434
86656208	86656231	10	+	26627737	HeLa	viability after 8 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.08442628324295495	[466]	[336,152,121]	-1	hSpCas9	negative selection	1434435
86658074	86658097	10	-	26627737	HeLa	viability after 8 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.6517799476263351	[965]	[186,153,431]	-6	hSpCas9	negative selection	1434436
86658672	86658695	10	-	26627737	HeLa	viability after 8 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.24454833214897634	[412]	[317,147,196]	2	hSpCas9	negative selection	1434437
86659356	86659379	10	-	26627737	HeLa	viability after 8 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.3192236043615078	[347]	[222,123,44]	-3	hSpCas9	negative selection	1434438
86660050	86660073	10	-	26627737	HeLa	viability after 8 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-0.3007432996648196	[1027]	[638,367,157]	-3	hSpCas9	negative selection	1434439
86654897	86654920	10	-	26627737	HeLa	viability after 12 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-0.8528922794411496	[217]	[26,77,40]	-7	hSpCas9	negative selection	1516749
86656208	86656231	10	+	26627737	HeLa	viability after 12 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	0.38546747940818243	[466]	[458,141,172]	3	hSpCas9	negative selection	1516750
86658074	86658097	10	-	26627737	HeLa	viability after 12 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-1.959417619687698	[965]	[87,50,173]	-9	hSpCas9	negative selection	1516751
86658672	86658695	10	-	26627737	HeLa	viability after 12 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.3260949611673417	[412]	[213,212,214]	3	hSpCas9	negative selection	1516752
86659356	86659379	10	-	26627737	HeLa	viability after 12 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.5757103029865291	[347]	[119,84,448]	5	hSpCas9	negative selection	1516753
86660050	86660073	10	-	26627737	HeLa	viability after 12 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.09628663497612533	[1027]	[700,431,238]	0	hSpCas9	negative selection	1516754
86654897	86654920	10	-	26627737	HeLa	viability after 15 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-0.37306599519309336	[217]	[81,95,23]	-3	hSpCas9	negative selection	1599064
86656208	86656231	10	+	26627737	HeLa	viability after 15 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.39545385580211123	[466]	[189,134,104]	-3	hSpCas9	negative selection	1599065
86658074	86658097	10	-	26627737	HeLa	viability after 15 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-1.0463567149938764	[965]	[180,155,237]	-7	hSpCas9	negative selection	1599066
86658672	86658695	10	-	26627737	HeLa	viability after 15 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.6449311817523096	[412]	[352,286,137]	5	hSpCas9	negative selection	1599067
86659356	86659379	10	-	26627737	HeLa	viability after 15 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.9170695583848163	[347]	[196,114,509]	7	hSpCas9	negative selection	1599068
86660050	86660073	10	-	26627737	HeLa	viability after 15 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.06639955245765283	[1027]	[668,453,167]	0	hSpCas9	negative selection	1599069
86654897	86654920	10	-	26627737	HeLa	viability after 18 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-0.5503307722379295	[217]	[47,68,23]	-5	hSpCas9	negative selection	1681379
86656208	86656231	10	+	26627737	HeLa	viability after 18 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.36052734764286865	[466]	[126,120,104]	-3	hSpCas9	negative selection	1681380
86658074	86658097	10	-	26627737	HeLa	viability after 18 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-1.068267858964266	[965]	[123,118,237]	-7	hSpCas9	negative selection	1681381
86658672	86658695	10	-	26627737	HeLa	viability after 18 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.7187132813206343	[412]	[260,240,137]	5	hSpCas9	negative selection	1681382
86659356	86659379	10	-	26627737	HeLa	viability after 18 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.9320764364760832	[347]	[132,100,509]	7	hSpCas9	negative selection	1681383
86660050	86660073	10	-	26627737	HeLa	viability after 18 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.033503338540826544	[1027]	[443,357,167]	0	hSpCas9	negative selection	1681384
86654897	86654920	10	-	26627737	HCT116	viability after 6 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-1.551532804403347	[328]	[16,17]	-7	hSpCas9	negative selection	1763694
86656208	86656231	10	+	26627737	HCT116	viability after 6 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.08675941981973445	[1162]	[137,190]	0	hSpCas9	negative selection	1763695
86658074	86658097	10	-	26627737	HCT116	viability after 6 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.021656307239601658	[869]	[172,119]	0	hSpCas9	negative selection	1763696
86658672	86658695	10	-	26627737	HCT116	viability after 6 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	1.1452250124245613	[530]	[513,2]	6	hSpCas9	negative selection	1763697
86659356	86659379	10	-	26627737	HCT116	viability after 6 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.44484134213001864	[609]	[9,196]	2	hSpCas9	negative selection	1763698
86660050	86660073	10	-	26627737	HCT116	viability after 6 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-0.1086222481070942	[2003]	[462,197]	0	hSpCas9	negative selection	1763699
86654897	86654920	10	-	26627737	HCT116	viability after 8 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	0.4083167171020097	[70]	[58,53,42]	4	hSpCas9	negative selection	1846009
86656208	86656231	10	+	26627737	HCT116	viability after 8 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	0.3848422853399993	[277]	[178,164,254]	4	hSpCas9	negative selection	1846010
86658074	86658097	10	-	26627737	HCT116	viability after 8 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.7552048836925007	[545]	[258,165,111]	-7	hSpCas9	negative selection	1846011
86658672	86658695	10	-	26627737	HCT116	viability after 8 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	-0.09749846096568787	[372]	[142,204,226]	-1	hSpCas9	negative selection	1846012
86659356	86659379	10	-	26627737	HCT116	viability after 8 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.2715611478803233	[244]	[268,76,144]	3	hSpCas9	negative selection	1846013
86660050	86660073	10	-	26627737	HCT116	viability after 8 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.2435529300140168	[436]	[309,285,259]	2	hSpCas9	negative selection	1846014
86654897	86654920	10	-	26627737	HCT116	viability after 9 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	0.01877946858462498	[328]	[26,137]	0	hSpCas9	negative selection	1928324
86656208	86656231	10	+	26627737	HCT116	viability after 9 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.6649971165551841	[1162]	[201,190]	-5	hSpCas9	negative selection	1928325
86658074	86658097	10	-	26627737	HCT116	viability after 9 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.8696930367516817	[869]	[519,348]	6	hSpCas9	negative selection	1928326
86658672	86658695	10	-	26627737	HCT116	viability after 9 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	1.0268526530955038	[530]	[575,61]	7	hSpCas9	negative selection	1928327
86659356	86659379	10	-	26627737	HCT116	viability after 9 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.6582757101826295	[609]	[105,100]	-5	hSpCas9	negative selection	1928328
86660050	86660073	10	-	26627737	HCT116	viability after 9 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.1681928343631922	[2003]	[612,591]	1	hSpCas9	negative selection	1928329
86654897	86654920	10	-	26627737	HCT116	viability after 12 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	1.3472107451029665	[70]	[148,51,77]	9	hSpCas9	negative selection	2010639
86656208	86656231	10	+	26627737	HCT116	viability after 12 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	0.832510130075149	[277]	[232,264,284]	7	hSpCas9	negative selection	2010640
86658074	86658097	10	-	26627737	HCT116	viability after 12 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.6089987232822553	[545]	[159,234,172]	-6	hSpCas9	negative selection	2010641
86658672	86658695	10	-	26627737	HCT116	viability after 12 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.10605898870876224	[372]	[184,284,166]	1	hSpCas9	negative selection	2010642
86659356	86659379	10	-	26627737	HCT116	viability after 12 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.4603376175955569	[244]	[212,164,149]	4	hSpCas9	negative selection	2010643
86660050	86660073	10	-	26627737	HCT116	viability after 12 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.5325836800273394	[436]	[246,369,387]	5	hSpCas9	negative selection	2010644
86654897	86654920	10	-	26627737	HCT116	viability after 15 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	1.4008418917705923	[70]	[127,49,146]	9	hSpCas9	negative selection	2092954
86656208	86656231	10	+	26627737	HCT116	viability after 15 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	0.561832503031199	[277]	[153,217,323]	5	hSpCas9	negative selection	2092955
86658074	86658097	10	-	26627737	HCT116	viability after 15 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.7687734381043857	[545]	[212,188,153]	-7	hSpCas9	negative selection	2092956
86658672	86658695	10	-	26627737	HCT116	viability after 15 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.2646232819524016	[372]	[351,212,218]	2	hSpCas9	negative selection	2092957
86659356	86659379	10	-	26627737	HCT116	viability after 15 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.37152337201340085	[244]	[175,240,128]	3	hSpCas9	negative selection	2092958
86660050	86660073	10	-	26627737	HCT116	viability after 15 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.5789095261090045	[436]	[381,493,250]	5	hSpCas9	negative selection	2092959
86654897	86654920	10	-	26627737	HCT116	viability after 18 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	1.72635549811847	[70]	[75,160,99]	9	hSpCas9	negative selection	2175269
86656208	86656231	10	+	26627737	HCT116	viability after 18 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	0.6024811132514395	[277]	[214,243,147]	5	hSpCas9	negative selection	2175270
86658074	86658097	10	-	26627737	HCT116	viability after 18 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.26485900841135446	[545]	[240,262,148]	-2	hSpCas9	negative selection	2175271
86658672	86658695	10	-	26627737	HCT116	viability after 18 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.3047668005112699	[372]	[189,280,191]	2	hSpCas9	negative selection	2175272
86659356	86659379	10	-	26627737	HCT116	viability after 18 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.8506687652226691	[244]	[216,218,203]	6	hSpCas9	negative selection	2175273
86660050	86660073	10	-	26627737	HCT116	viability after 18 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.7138395969393936	[436]	[346,213,493]	6	hSpCas9	negative selection	2175274
86658128	86658151	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.3494204883272036	[3,3]	[4,3]	7	hSpCas9	positive selection	3007440
86658112	86658135	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.015467148017330068	[4,4]	[4,3]	0	hSpCas9	positive selection	3007441
86659338	86659361	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	0.5750923455947756	[4,4]	[3,7]	9	hSpCas9	positive selection	3007442
86658074	86658097	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.42137343372650016	[4,4]	[4,6]	8	hSpCas9	positive selection	3007443
86658128	86658151	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.1108539709021695	[3,3]	[4,1]	2	hSpCas9	positive selection	3075298
86658112	86658135	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	-0.0700105020532989	[4,4]	[3,2]	-1	hSpCas9	positive selection	3075299
86659338	86659361	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	0.14042889697707034	[4,4]	[3,2]	2	hSpCas9	positive selection	3075300
86658074	86658097	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.15045429600998517	[4,4]	[4,2]	2	hSpCas9	positive selection	3075301
86656274	86656297		-	24336571	A375	resistance to PLX after 7 days	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.1544136896812679	[14,14]	[13,11]	-5	hSpCas9	positive selection	3132490
86656192	86656215		-	24336571	A375	resistance to PLX after 7 days	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.43247409074472964	[4,3]	[6,5]	9	hSpCas9	positive selection	3132491
86657187	86657210		+	24336571	A375	resistance to PLX after 7 days	CAAAACAGAGCTGTGCTTCGTGG	OPN4	ENSG00000122375	-0.06701614575530979	[9,7]	[7,8]	-2	hSpCas9	positive selection	3132492
86658074	86658097		-	24336571	A375	resistance to PLX after 7 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.21279009867629606	[7,8]	[7,6]	-6	hSpCas9	positive selection	3132493
86656274	86656297		-	24336571	A375	resistance to PLX after 14 days	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.6753434341628406	[14,16]	[3,4]	-7	hSpCas9	positive selection	3190283
86656192	86656215		-	24336571	A375	resistance to PLX after 14 days	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.00843133786241923	[4,3]	[1,1]	0	hSpCas9	positive selection	3190284
86657187	86657210		+	24336571	A375	resistance to PLX after 14 days	CAAAACAGAGCTGTGCTTCGTGG	OPN4	ENSG00000122375	-0.4486098087748094	[6,9]	[2,2]	-5	hSpCas9	positive selection	3190285
86658074	86658097		-	24336571	A375	resistance to PLX after 14 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.5736644625056877	[8,6]	[3,5]	5	hSpCas9	positive selection	3190286
86656274	86656297		-	24336571	A375	viability after 7 days	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	0.260475220702451	[12]	[14,14]	4	hSpCas9	negative selection	3248076
86656192	86656215		-	24336571	A375	viability after 7 days	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.0732547168084885	[4]	[4,3]	-1	hSpCas9	negative selection	3248077
86657187	86657210		+	24336571	A375	viability after 7 days	CAAAACAGAGCTGTGCTTCGTGG	OPN4	ENSG00000122375	0.0465135295728738	[8]	[9,7]	0	hSpCas9	negative selection	3248078
86658074	86658097		-	24336571	A375	viability after 7 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.30887586758139607	[10]	[7,8]	-4	hSpCas9	negative selection	3248079
86656274	86656297		-	24336571	A375	viability after 14 days	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	0.3692483060882683	[12]	[14,16]	5	hSpCas9	negative selection	3305869
86656192	86656215		-	24336571	A375	viability after 14 days	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.17365662099509938	[4]	[4,3]	-2	hSpCas9	negative selection	3305870
86657187	86657210		+	24336571	A375	viability after 14 days	CAAAACAGAGCTGTGCTTCGTGG	OPN4	ENSG00000122375	0.08566020911335148	[8]	[6,9]	1	hSpCas9	negative selection	3305871
86658074	86658097		-	24336571	A375	viability after 14 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.4349826700275399	[10]	[8,6]	-5	hSpCas9	negative selection	3305872
86658629	86658652	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	2.687470603114887	[189,189]	[7,7]	8	hSpCas9	positive selection	3383053
86656192	86656215	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.31505822319585164	[570,570]	[2,2]	-2	hSpCas9	positive selection	3383054
86658127	86658150	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	3.169863370195496	[16,16]	[0,0]	8	hSpCas9	positive selection	3383055
86658127	86658150	10	+	26780180	HT29	viability (Avana library 4 designs)	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.220046511315921	[]	[]	0	hSpCas9	negative selection	3445374
86658112	86658135	10	-	26780180	HT29	viability (Avana library 4 designs)	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.55216018549652	[]	[]	2	hSpCas9	negative selection	3445375
86659337	86659360	10	+	26780180	HT29	viability (Avana library 4 designs)	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	1.3393389523414	[]	[]	5	hSpCas9	negative selection	3445376
86658074	86658097	10	-	26780180	HT29	viability (Avana library 4 designs)	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.361141013366328	[]	[]	1	hSpCas9	negative selection	3445377
86658074	86658097	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	4.27971843310195	[]	[]	7	hSpCas9	negative selection	3538073
86659337	86659360	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	-5.74821623115774	[]	[]	-6	hSpCas9	negative selection	3538074
86658112	86658135	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	-0.499183969017484	[]	[]	0	hSpCas9	negative selection	3538075
86658127	86658150	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.247449088155093	[]	[]	0	hSpCas9	negative selection	3538076
86658592	86658615	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTTGGTGTGGCGTCCAAGAGG	OPN4	ENSG00000122375	1.21136431519382	[]	[]	1	hSpCas9	negative selection	3538077
86656175	86656198	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGCCTGGGTCCCCCTCCCCACGG	OPN4	ENSG00000122375	-6.32938135795345	[]	[]	-6	hSpCas9	negative selection	3538078
86658074	86658097	10	-	26780180	A375	viability (Avana lentiGuide)	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.127389980544869	[]	[]	0	hSpCas9	negative selection	3646732
86659337	86659360	10	+	26780180	A375	viability (Avana lentiGuide)	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	4.84843152061147	[]	[]	4	hSpCas9	negative selection	3646733
86658112	86658135	10	-	26780180	A375	viability (Avana lentiGuide)	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	4.1135261409103	[]	[]	4	hSpCas9	negative selection	3646734
86658127	86658150	10	+	26780180	A375	viability (Avana lentiGuide)	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	1.66811266526639	[]	[]	2	hSpCas9	negative selection	3646735
86658592	86658615	10	+	26780180	A375	viability (Avana lentiGuide)	CCTTTGGTGTGGCGTCCAAGAGG	OPN4	ENSG00000122375	0.206203681904589	[]	[]	0	hSpCas9	negative selection	3646736
86656175	86656198	10	+	26780180	A375	viability (Avana lentiGuide)	TGCCTGGGTCCCCCTCCCCACGG	OPN4	ENSG00000122375	19.698810198175	[]	[]	8	hSpCas9	negative selection	3646737
86658074	86658097	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.10628720500843791	[5]	[6,5]	2	hSpCas9	positive selection	3755391
86659337	86659360	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	-0.6467054349899581	[5]	[4,2]	-7	hSpCas9	positive selection	3755392
86658112	86658135	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.02682060534602651	[5]	[6,4]	0	hSpCas9	positive selection	3755393
86658127	86658150	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.1189183957666914	[5]	[3,4]	-2	hSpCas9	positive selection	3755394
86658592	86658615	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTTGGTGTGGCGTCCAAGAGG	OPN4	ENSG00000122375	0.09291641870019873	[4]	[5,4]	2	hSpCas9	positive selection	3755395
86656175	86656198	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCCTGGGTCCCCCTCCCCACGG	OPN4	ENSG00000122375	-0.7335080374099605	[4]	[3,1]	-8	hSpCas9	positive selection	3755396
86658074	86658097	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.2324070511702316	[6]	[6,6]	6	hSpCas9	positive selection	3863998
86659337	86659360	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	-0.5933177638248783	[7]	[2,4]	-6	hSpCas9	positive selection	3863999
86658112	86658135	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.021179173624757408	[6]	[4,5]	0	hSpCas9	positive selection	3864000
86658127	86658150	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.3886775508859222	[5]	[5,6]	9	hSpCas9	positive selection	3864001
86658592	86658615	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTTGGTGTGGCGTCCAAGAGG	OPN4	ENSG00000122375	0.2674147025079279	[5]	[4,5]	7	hSpCas9	positive selection	3864002
86656175	86656198	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCCTGGGTCCCCCTCCCCACGG	OPN4	ENSG00000122375	-1.6605950965004959	[4]	[0,1]	-9	hSpCas9	positive selection	3864003
86656274	86656297	10	-	26780180	A375	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	1.07404701822147	[]	[]	5	hSpCas9	negative selection	3975138
86656192	86656215	10	-	26780180	A375	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	1.12758595100098	[]	[]	5	hSpCas9	negative selection	3975139
86658629	86658652	10	-	26780180	A375	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	1.19467111499934	[]	[]	6	hSpCas9	negative selection	3975140
86658566	86658589	10	-	26780180	A375	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	1.05835182137397	[]	[]	5	hSpCas9	negative selection	3975141
86658127	86658150	10	+	26780180	A375	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.538842126609295	[]	[]	1	hSpCas9	negative selection	3975142
86658074	86658097	10	-	26780180	A375	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	1.4100114413531	[]	[]	7	hSpCas9	negative selection	3975143
86656274	86656297	10	-	26780180	HT29	viability (GeCKOv2 library)	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	1.98870862945039	[]	[]	9	hSpCas9	negative selection	4083104
86656192	86656215	10	-	26780180	HT29	viability (GeCKOv2 library)	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.0343750580955334	[]	[]	0	hSpCas9	negative selection	4083105
86658629	86658652	10	-	26780180	HT29	viability (GeCKOv2 library)	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	1.46339703687913	[]	[]	7	hSpCas9	negative selection	4083106
86658566	86658589	10	-	26780180	HT29	viability (GeCKOv2 library)	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	1.24854885539051	[]	[]	6	hSpCas9	negative selection	4083107
86658127	86658150	10	+	26780180	HT29	viability (GeCKOv2 library)	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.417502933538649	[]	[]	1	hSpCas9	negative selection	4083108
86658074	86658097	10	-	26780180	HT29	viability (GeCKOv2 library)	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	1.00034835398047	[]	[]	4	hSpCas9	negative selection	4083109
86656274	86656297	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.04902077769028465	[3]	[2,1]	-1	hSpCas9	positive selection	4157283
86656192	86656215	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.6287185379210338	[2]	[1,0]	-9	hSpCas9	positive selection	4157284
86657187	86657210	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAAAACAGAGCTGTGCTTCGTGG	OPN4	ENSG00000122375	-0.2199055062119769	[3]	[2,1]	-5	hSpCas9	positive selection	4157285
86658074	86658097	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.06065826634751492	[3]	[1,2]	1	hSpCas9	positive selection	4157286
86656274	86656297	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.5135035885429344	[3]	[0,0,2,0]	-7	hSpCas9	positive selection	4221305
86656192	86656215	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.07768150278877756	[4]	[3,1,1,0]	-1	hSpCas9	positive selection	4221306
86657187	86657210	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAAAACAGAGCTGTGCTTCGTGG	OPN4	ENSG00000122375	0.1538096832652356	[2]	[1,3,0,0]	1	hSpCas9	positive selection	4221307
86658074	86658097	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.17811326677773393	[3]	[0,0,2,0]	-3	hSpCas9	positive selection	4221308
86658566	86658589	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.05864854257298302	[1]	[1,0]	1	hSpCas9	positive selection	4287090
86658074	86658097	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.24049689672848373	[2]	[2,2]	5	hSpCas9	positive selection	4287091
86656274	86656297	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.1130678234285939	[2]	[0,2]	-2	hSpCas9	positive selection	4287092
86658629	86658652	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.05909281641574081	[3]	[2,1]	-1	hSpCas9	positive selection	4351345
86656192	86656215	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.31494187723367245	[4]	[4,4]	6	hSpCas9	positive selection	4351346
86658127	86658150	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.16392981995182576	[0]	[0,0]	3	hSpCas9	positive selection	4351347
86656192	86656214	10	-	27760321	OCIAML3	viability	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.4927241606234883	[461,445]	[424,598]	6	hSpCas9	negative selection	4424660
86658567	86658589	10	+	27760321	OCIAML3	viability	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	0.09429125450005527	[623,528]	[450,516]	1	hSpCas9	negative selection	4424661
86658629	86658651	10	-	27760321	OCIAML3	viability	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.6363289888931281	[346,257]	[268,488]	7	hSpCas9	negative selection	4424662
86659295	86659317	10	+	27760321	OCIAML3	viability	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.26555854624757724	[379,301]	[223,441]	3	hSpCas9	negative selection	4424663
86659356	86659378	10	-	27760321	OCIAML3	viability	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.16794135995142173	[351,307]	[233,222]	-2	hSpCas9	negative selection	4424664
86656192	86656214	10	-	27760321	OCIAML2	viability	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.7376307567623863	[461,445]	[474,795]	8	hSpCas9	negative selection	4508123
86658567	86658589	10	+	27760321	OCIAML2	viability	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	0.0039567234885547475	[623,528]	[462,469]	0	hSpCas9	negative selection	4508124
86658629	86658651	10	-	27760321	OCIAML2	viability	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.2377998665514432	[346,257]	[219,372]	3	hSpCas9	negative selection	4508125
86659295	86659317	10	+	27760321	OCIAML2	viability	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.16461677606167346	[379,301]	[261,366]	2	hSpCas9	negative selection	4508126
86659356	86659378	10	-	27760321	OCIAML2	viability	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.3167585678479106	[351,307]	[301,370]	4	hSpCas9	negative selection	4508127
86656192	86656214	10	-	27760321	MV411	viability	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.452468649222773	[461,445]	[305,567]	3	hSpCas9	negative selection	4591586
86658567	86658589	10	+	27760321	MV411	viability	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	0.3048098046445609	[623,528]	[343,654]	2	hSpCas9	negative selection	4591587
86658629	86658651	10	-	27760321	MV411	viability	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	1.5559348136183395	[346,257]	[546,633]	9	hSpCas9	negative selection	4591588
86659295	86659317	10	+	27760321	MV411	viability	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	-1.232794259984381	[379,301]	[49,162]	-7	hSpCas9	negative selection	4591589
86659356	86659378	10	-	27760321	MV411	viability	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.709371220807234	[351,307]	[222,553]	5	hSpCas9	negative selection	4591590
86656192	86656214	10	-	27760321	HL60	viability	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.18053148151925977	[461,445]	[439,400]	2	hSpCas9	negative selection	4675049
86658567	86658589	10	+	27760321	HL60	viability	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	-0.09986983202506539	[623,528]	[384,493]	-1	hSpCas9	negative selection	4675050
86658629	86658651	10	-	27760321	HL60	viability	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.34668034816065607	[346,257]	[243,382]	4	hSpCas9	negative selection	4675051
86659295	86659317	10	+	27760321	HL60	viability	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.5831230825881957	[379,301]	[505,317]	7	hSpCas9	negative selection	4675052
86659356	86659378	10	-	27760321	HL60	viability	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.1533348328684307	[351,307]	[220,381]	1	hSpCas9	negative selection	4675053
86656192	86656214	10	-	27760321	HT1080	viability	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.5313893625656334	[445,347]	[303,145]	3	hSpCas9	negative selection	4758512
86658567	86658589	10	+	27760321	HT1080	viability	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	-0.04494008373519448	[528,412]	[210,149]	0	hSpCas9	negative selection	4758513
86658629	86658651	10	-	27760321	HT1080	viability	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.6466175311506777	[257,201]	[205,74]	3	hSpCas9	negative selection	4758514
86659295	86659317	10	+	27760321	HT1080	viability	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.6730643670852883	[301,235]	[220,115]	3	hSpCas9	negative selection	4758515
86659356	86659378	10	-	27760321	HT1080	viability	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.24569265047118888	[307,240]	[128,51]	-1	hSpCas9	negative selection	4758516
86656192	86656214	10	-	27760321	HT29	viability after 7 days	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.23970750162502788	[445,347]	[759,342,245]	-3	hSpCas9	negative selection	4841975
86658567	86658589	10	+	27760321	HT29	viability after 7 days	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	0.2750724855571885	[528,412]	[489,790,876]	4	hSpCas9	negative selection	4841976
86658629	86658651	10	-	27760321	HT29	viability after 7 days	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.9188937631412866	[257,201]	[599,598,485]	9	hSpCas9	negative selection	4841977
86659295	86659317	10	+	27760321	HT29	viability after 7 days	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.6716233382336784	[301,235]	[691,487,493]	8	hSpCas9	negative selection	4841978
86659356	86659378	10	-	27760321	HT29	viability after 7 days	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.32578094356450105	[307,240]	[461,539,330]	5	hSpCas9	negative selection	4841979
86656192	86656214	10	-	27760321	HT29	viability after 25 days	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.2149481937056311	[445,347]	[506,307,344]	-2	hSpCas9	negative selection	4925438
86658567	86658589	10	+	27760321	HT29	viability after 25 days	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	-0.10848029739461656	[528,412]	[521,531,434]	-1	hSpCas9	negative selection	4925439
86658629	86658651	10	-	27760321	HT29	viability after 25 days	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.45751331849275584	[257,201]	[330,317,443]	5	hSpCas9	negative selection	4925440
86659295	86659317	10	+	27760321	HT29	viability after 25 days	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.6015890862985629	[301,235]	[437,354,623]	6	hSpCas9	negative selection	4925441
86659356	86659378	10	-	27760321	HT29	viability after 25 days	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.05710365980528159	[307,240]	[363,254,278]	0	hSpCas9	negative selection	4925442
86656192	86656214	10	-	27760321	HT29	viability after 22 days	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.04999070240759085	[445,347]	[352,564,510]	0	hSpCas9	negative selection	5008901
86658567	86658589	10	+	27760321	HT29	viability after 22 days	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	0.0331846896045635	[528,412]	[556,402,712]	0	hSpCas9	negative selection	5008902
86658629	86658651	10	-	27760321	HT29	viability after 22 days	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	1.0758740925392363	[257,201]	[751,429,493]	9	hSpCas9	negative selection	5008903
86659295	86659317	10	+	27760321	HT29	viability after 22 days	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.5065526850835023	[301,235]	[337,366,624]	5	hSpCas9	negative selection	5008904
86659356	86659378	10	-	27760321	HT29	viability after 22 days	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.32355530216349865	[307,240]	[147,331,283]	-3	hSpCas9	negative selection	5008905
86656192	86656214	10	-	27760321	HT29	viability after 19 days	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.061380874085059295	[445,347]	[618,284,529]	0	hSpCas9	negative selection	5092364
86658567	86658589	10	+	27760321	HT29	viability after 19 days	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	-0.09000007663417714	[528,412]	[497,616,405]	-1	hSpCas9	negative selection	5092365
86658629	86658651	10	-	27760321	HT29	viability after 19 days	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.5751071634784188	[257,201]	[510,41,625]	6	hSpCas9	negative selection	5092366
86659295	86659317	10	+	27760321	HT29	viability after 19 days	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.6210141620839124	[301,235]	[628,398,409]	6	hSpCas9	negative selection	5092367
86659356	86659378	10	-	27760321	HT29	viability after 19 days	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.9092466524505456	[307,240]	[229,136,141]	-6	hSpCas9	negative selection	5092368
86656192	86656214	10	-	27760321	HT29	viability after 16 days	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.13882222699740582	[445,347]	[747,467,275]	1	hSpCas9	negative selection	5175827
86658567	86658589	10	+	27760321	HT29	viability after 16 days	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	-0.24267733822697976	[528,412]	[524,467,349]	-3	hSpCas9	negative selection	5175828
86658629	86658651	10	-	27760321	HT29	viability after 16 days	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.8864564897258999	[257,201]	[345,438,630]	9	hSpCas9	negative selection	5175829
86659295	86659317	10	+	27760321	HT29	viability after 16 days	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.686121827980912	[301,235]	[593,410,459]	7	hSpCas9	negative selection	5175830
86659356	86659378	10	-	27760321	HT29	viability after 16 days	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.07750323741080689	[307,240]	[302,304,265]	-1	hSpCas9	negative selection	5175831
86656192	86656214	10	-	27760321	HT29	viability after 13 days	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.1298023667798558	[445,347]	[610,474,429]	1	hSpCas9	negative selection	5259290
86658567	86658589	10	+	27760321	HT29	viability after 13 days	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	0.18127844334019	[528,412]	[623,774,468]	2	hSpCas9	negative selection	5259291
86658629	86658651	10	-	27760321	HT29	viability after 13 days	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.15641904837752285	[257,201]	[257,164,291]	-2	hSpCas9	negative selection	5259292
86659295	86659317	10	+	27760321	HT29	viability after 13 days	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.5598147183954054	[301,235]	[452,601,332]	7	hSpCas9	negative selection	5259293
86659356	86659378	10	-	27760321	HT29	viability after 13 days	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.1270138350552632	[307,240]	[423,199,414]	1	hSpCas9	negative selection	5259294
86656192	86656214	10	-	27760321	HT29	viability after 10 days	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.06307351839068774	[445,347]	[456,515,451]	-1	hSpCas9	negative selection	5342753
86658567	86658589	10	+	27760321	HT29	viability after 10 days	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	0.08687061936431179	[528,412]	[512,781,583]	1	hSpCas9	negative selection	5342754
86658629	86658651	10	-	27760321	HT29	viability after 10 days	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.6680477265824043	[257,201]	[481,523,366]	8	hSpCas9	negative selection	5342755
86659295	86659317	10	+	27760321	HT29	viability after 10 days	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.2069020093629748	[301,235]	[456,396,310]	2	hSpCas9	negative selection	5342756
86659356	86659378	10	-	27760321	HT29	viability after 10 days	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.056444797842754635	[307,240]	[380,349,259]	0	hSpCas9	negative selection	5342757
86656192	86656214	10	-	27760321	MOLM13	viability	TGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.18325419407174387	[461,445]	[319,266]	1	hSpCas9	negative selection	5426216
86658567	86658589	10	+	27760321	MOLM13	viability	CTGGTAATCACACGCCCGCTGG	OPN4	ENSG00000122375	-0.014308347464812077	[623,528]	[294,342]	0	hSpCas9	negative selection	5426217
86658629	86658651	10	-	27760321	MOLM13	viability	ATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.06058422225005072	[346,257]	[163,186]	0	hSpCas9	negative selection	5426218
86659295	86659317	10	+	27760321	MOLM13	viability	AGGCGCCTACGTGCCCGAGGGG	OPN4	ENSG00000122375	0.24462792995964594	[379,301]	[393,83]	1	hSpCas9	negative selection	5426219
86659356	86659378	10	-	27760321	MOLM13	viability	TGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.21562476814421533	[351,307]	[139,176]	-1	hSpCas9	negative selection	5426220
86654628	86654651	10	+	27661255	K562	viability	GCTGGATCTGCGCCGGACACAGG	OPN4	ENSG00000122375	0.290883593760977	[512,527]	[563,460]	8	dCas9-KRAB	negative selection	5498471
86654588	86654611	10	-	27661255	K562	viability	GCTGGCGGTTGCTCTGTGTCTGG	OPN4	ENSG00000122375	-0.16375958896886056	[630,596]	[508,377]	-5	dCas9-KRAB	negative selection	5498472
86658566	86658589	10	-	27260156	BXPC3	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.31483317391099463	[140]	[173,229,180,139]	6	hSpCas9	negative selection	5559550
86658074	86658097	10	-	27260156	BXPC3	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.03648411437275191	[448]	[384,414,495,554]	-1	hSpCas9	negative selection	5559551
86656274	86656297	10	-	27260156	BXPC3	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.7646568011178141	[277]	[175,191,106,209]	-9	hSpCas9	negative selection	5559552
86658629	86658652	10	-	27260156	BXPC3	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.03754252240950584	[524]	[488,520,452,696]	-1	hSpCas9	negative selection	5623805
86656192	86656215	10	-	27260156	BXPC3	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.030143061883522337	[1589]	[1671,1443,1635,1772]	0	hSpCas9	negative selection	5623806
86658127	86658150	10	+	27260156	BXPC3	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.14673155482788935	[40]	[17,25,36,81]	-3	hSpCas9	negative selection	5623807
86658566	86658589	10	-	27260156	A673	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.6415703062647946	[140]	[226,288,196,342]	9	hSpCas9	negative selection	5680801
86658074	86658097	10	-	27260156	A673	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.018525018802387827	[448]	[561,573,504,486]	0	hSpCas9	negative selection	5680802
86656274	86656297	10	-	27260156	A673	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.45246167721327146	[277]	[344,217,183,240]	-8	hSpCas9	negative selection	5680803
86658629	86658652	10	-	27260156	A673	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.05976677727505006	[524]	[630,600,656,740]	1	hSpCas9	negative selection	5745056
86656192	86656215	10	-	27260156	A673	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.1377198117794194	[1589]	[1832,1701,1789,1617]	-3	hSpCas9	negative selection	5745057
86658127	86658150	10	+	27260156	A673	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.05976554893404584	[40]	[77,41,45,41]	1	hSpCas9	negative selection	5745058
86658566	86658589	10	-	27260156	A375	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.6947271477074954	[140]	[190,269,317,283]	8	hSpCas9	negative selection	5802052
86658074	86658097	10	-	27260156	A375	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.4483821060584179	[448]	[320,421,342,446]	-6	hSpCas9	negative selection	5802053
86656274	86656297	10	-	27260156	A375	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.6343256562539388	[277]	[114,288,266,178]	-7	hSpCas9	negative selection	5802054
86658629	86658652	10	-	27260156	A375	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.24030936451347326	[524]	[985,980,553,444]	3	hSpCas9	negative selection	5866307
86656192	86656215	10	-	27260156	A375	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.2909507056148559	[1589]	[1646,1609,1539,1307]	-4	hSpCas9	negative selection	5866308
86658127	86658150	10	+	27260156	A375	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.01963401854345248	[40]	[62,27,67,33]	0	hSpCas9	negative selection	5866309
86658566	86658589	10	-	27260156	COLO741	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.4877485570376434	[140]	[293,189,274]	8	hSpCas9	negative selection	5923303
86658074	86658097	10	-	27260156	COLO741	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.10794523440626033	[448]	[810,518,544]	2	hSpCas9	negative selection	5923304
86656274	86656297	10	-	27260156	COLO741	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.7098505232984831	[277]	[369,164,134]	-9	hSpCas9	negative selection	5923305
86658629	86658652	10	-	27260156	COLO741	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.00864706854644448	[524]	[748,770,520]	0	hSpCas9	negative selection	5987558
86656192	86656215	10	-	27260156	COLO741	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.20795374835890867	[1589]	[2781,2075,2221]	4	hSpCas9	negative selection	5987559
86658127	86658150	10	+	27260156	COLO741	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.20132735494003473	[40]	[82,46,52]	4	hSpCas9	negative selection	5987560
86658566	86658589	10	-	27260156	CAL120	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	-0.04198296040423277	[140]	[182,209,120]	0	hSpCas9	negative selection	6044554
86658074	86658097	10	-	27260156	CAL120	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.1369402795870677	[448]	[314,384,789]	-2	hSpCas9	negative selection	6044555
86656274	86656297	10	-	27260156	CAL120	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.9447312284508074	[277]	[123,186,218]	-8	hSpCas9	negative selection	6044556
86658629	86658652	10	-	27260156	CAL120	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.011321250282503775	[524]	[436,740,732]	0	hSpCas9	negative selection	6108809
86656192	86656215	10	-	27260156	CAL120	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.46331472503764193	[1589]	[1794,1472,1096]	-6	hSpCas9	negative selection	6108810
86658127	86658150	10	+	27260156	CAL120	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.8682996113987147	[40]	[30,8,43]	-8	hSpCas9	negative selection	6108811
86658566	86658589	10	-	27260156	CADOES1	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.571162592516057	[140]	[139,235,222,179]	8	hSpCas9	negative selection	6165805
86658074	86658097	10	-	27260156	CADOES1	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.08519499636248068	[448]	[420,268,445,439]	-1	hSpCas9	negative selection	6165806
86656274	86656297	10	-	27260156	CADOES1	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.39544835176813575	[277]	[165,218,112,291]	-6	hSpCas9	negative selection	6165807
86658629	86658652	10	-	27260156	CADOES1	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.21677994828987254	[524]	[624,441,567,636]	3	hSpCas9	negative selection	6230060
86656192	86656215	10	-	27260156	CADOES1	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.09923259512983273	[1589]	[1547,1448,1137,1386]	-2	hSpCas9	negative selection	6230061
86658127	86658150	10	+	27260156	CADOES1	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.6351511962702241	[40]	[9,8,8,71]	-8	hSpCas9	negative selection	6230062
86658566	86658589	10	-	27260156	EWS502	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.46500872268239624	[140]	[212,190,191,228]	7	hSpCas9	negative selection	6287056
86658074	86658097	10	-	27260156	EWS502	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.02070719128466545	[448]	[456,388,616,472]	0	hSpCas9	negative selection	6287057
86656274	86656297	10	-	27260156	EWS502	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	0.06834091539044429	[277]	[261,235,407,339]	1	hSpCas9	negative selection	6287058
86658629	86658652	10	-	27260156	EWS502	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.03866586524095854	[524]	[367,470,649,711]	0	hSpCas9	negative selection	6351311
86656192	86656215	10	-	27260156	EWS502	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.04851974255620961	[1589]	[1619,1558,1594,1744]	-1	hSpCas9	negative selection	6351312
86658127	86658150	10	+	27260156	EWS502	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.47858958229982784	[40]	[10,44,31,38]	-7	hSpCas9	negative selection	6351313
86658566	86658589	10	-	27260156	EW8	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.6183528007029888	[140]	[113,202,153,226]	9	hSpCas9	negative selection	6408307
86658074	86658097	10	-	27260156	EW8	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.235588810922482	[448]	[322,478,481,407]	4	hSpCas9	negative selection	6408308
86656274	86656297	10	-	27260156	EW8	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.44035287463690165	[277]	[223,183,149,114]	-7	hSpCas9	negative selection	6408309
86658629	86658652	10	-	27260156	EW8	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.07665301290259233	[524]	[442,553,242,404]	-1	hSpCas9	negative selection	6472562
86656192	86656215	10	-	27260156	EW8	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.11355597190165634	[1589]	[1400,1363,960,1097]	-2	hSpCas9	negative selection	6472563
86658127	86658150	10	+	27260156	EW8	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.4822647297091618	[40]	[74,3,9,13]	-7	hSpCas9	negative selection	6472564
86658566	86658589	10	-	27260156	CORL105	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.6784678080062869	[140]	[270,220,391,193]	9	hSpCas9	negative selection	6529558
86658074	86658097	10	-	27260156	CORL105	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.15095394076683033	[448]	[553,367,496,482]	-3	hSpCas9	negative selection	6529559
86656274	86656297	10	-	27260156	CORL105	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.43667128625778306	[277]	[239,149,245,327]	-7	hSpCas9	negative selection	6529560
86658629	86658652	10	-	27260156	CORL105	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.01667182627332664	[524]	[508,664,711,555]	0	hSpCas9	negative selection	6593813
86656192	86656215	10	-	27260156	CORL105	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.154889704926352	[1589]	[1413,1622,2122,1589]	-3	hSpCas9	negative selection	6593814
86658127	86658150	10	+	27260156	CORL105	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.04237036256612736	[40]	[25,72,63,24]	-1	hSpCas9	negative selection	6593815
86658566	86658589	10	-	27260156	HS294T	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.8024589104385746	[140]	[74,88,98,123]	8	hSpCas9	negative selection	6650809
86658074	86658097	10	-	27260156	HS294T	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.7237565544092954	[448]	[300,291,300,242]	8	hSpCas9	negative selection	6650810
86656274	86656297	10	-	27260156	HS294T	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.49906008968346005	[277]	[80,55,66,104]	-6	hSpCas9	negative selection	6650811
86658629	86658652	10	-	27260156	HS294T	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.20694817685377906	[524]	[147,232,258,318]	3	hSpCas9	negative selection	6715064
86656192	86656215	10	-	27260156	HS294T	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.2643916212905184	[1589]	[496,513,463,583]	-4	hSpCas9	negative selection	6715065
86658127	86658150	10	+	27260156	HS294T	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-1.2503194874979813	[40]	[2,7,3,12]	-9	hSpCas9	negative selection	6715066
86658566	86658589	10	-	27260156	HCC44	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.5307378103435105	[140]	[160,121,351,311]	8	hSpCas9	negative selection	6772060
86658074	86658097	10	-	27260156	HCC44	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.027805773729607394	[448]	[443,384,563,687]	0	hSpCas9	negative selection	6772061
86656274	86656297	10	-	27260156	HCC44	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.6425582955987452	[277]	[194,154,305,172]	-7	hSpCas9	negative selection	6772062
86658629	86658652	10	-	27260156	HCC44	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.30788443088155304	[524]	[882,603,950,570]	5	hSpCas9	negative selection	6836315
86656192	86656215	10	-	27260156	HCC44	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.0747287439263975	[1589]	[1997,1836,2159,1636]	1	hSpCas9	negative selection	6836316
86658127	86658150	10	+	27260156	HCC44	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.5014616695739473	[40]	[9,112,53,70]	8	hSpCas9	negative selection	6836317
86658566	86658589	10	-	27260156	G402	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.7178871766552635	[140]	[487,322,73,277]	8	hSpCas9	negative selection	6893311
86658074	86658097	10	-	27260156	G402	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.7897976796100142	[448]	[424,228,244,374]	-7	hSpCas9	negative selection	6893312
86656274	86656297	10	-	27260156	G402	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.4785234006413228	[277]	[185,275,165,333]	-5	hSpCas9	negative selection	6893313
86658629	86658652	10	-	27260156	G402	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.10626047567343519	[524]	[905,596,811,476]	1	hSpCas9	negative selection	6957566
86656192	86656215	10	-	27260156	G402	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.19535823454774826	[1589]	[1748,1630,1567,1820]	-2	hSpCas9	negative selection	6957567
86658127	86658150	10	+	27260156	G402	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.027062364040745912	[40]	[2,24,1,152]	0	hSpCas9	negative selection	6957568
86658566	86658589	10	-	27260156	L33	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.547994243034591	[140]	[175,89,139,206]	9	hSpCas9	negative selection	7014562
86658074	86658097	10	-	27260156	L33	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.2894597712550104	[448]	[524,205,406,520]	6	hSpCas9	negative selection	7014563
86656274	86656297	10	-	27260156	L33	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.5928880769276406	[277]	[148,85,160,123]	-8	hSpCas9	negative selection	7014564
86658629	86658652	10	-	27260156	L33	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.004546732459174446	[524]	[578,207,313,518]	0	hSpCas9	negative selection	7078817
86656192	86656215	10	-	27260156	L33	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.12737723759342434	[1589]	[1337,632,890,1523]	-3	hSpCas9	negative selection	7078818
86658127	86658150	10	+	27260156	L33	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.7086201148358948	[40]	[20,9,23,16]	-9	hSpCas9	negative selection	7078819
86658566	86658589	10	-	27260156	K562	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.8606869751285297	[140]	[334,264,263,72]	9	hSpCas9	negative selection	7135813
86658074	86658097	10	-	27260156	K562	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.1352561983976992	[448]	[441,314,478,232]	-2	hSpCas9	negative selection	7135814
86656274	86656297	10	-	27260156	K562	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	0.21740880450659517	[277]	[319,452,186,206]	2	hSpCas9	negative selection	7135815
86658629	86658652	10	-	27260156	K562	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.09576244635222561	[524]	[926,425,379,309]	1	hSpCas9	negative selection	7200068
86656192	86656215	10	-	27260156	K562	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.17782759590683317	[1589]	[892,1539,954,1546]	-2	hSpCas9	negative selection	7200069
86658127	86658150	10	+	27260156	K562	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-1.1891118346637657	[40]	[16,7,8,27]	-8	hSpCas9	negative selection	7200070
86658566	86658589	10	-	27260156	HT29	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.5400967938950567	[140]	[291,313,229,176]	9	hSpCas9	negative selection	7257064
86658074	86658097	10	-	27260156	HT29	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.11939053591250548	[448]	[486,595,579,366]	-2	hSpCas9	negative selection	7257065
86656274	86656297	10	-	27260156	HT29	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.36427071481745577	[277]	[232,315,305,202]	-6	hSpCas9	negative selection	7257066
86658629	86658652	10	-	27260156	HT29	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.12494313046193237	[524]	[694,728,908,475]	2	hSpCas9	negative selection	7321319
86656192	86656215	10	-	27260156	HT29	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.0925287968544728	[1589]	[2040,1717,1960,1558]	-2	hSpCas9	negative selection	7321320
86658127	86658150	10	+	27260156	HT29	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.06376306340645899	[40]	[53,82,27,30]	-1	hSpCas9	negative selection	7321321
86658566	86658589	10	-	27260156	MHHES1	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	1.1477526746923816	[140]	[423,364,410,236]	9	hSpCas9	negative selection	7378315
86658074	86658097	10	-	27260156	MHHES1	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.08361715611126738	[448]	[579,443,519,384]	-1	hSpCas9	negative selection	7378316
86656274	86656297	10	-	27260156	MHHES1	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.4504012235949182	[277]	[295,313,168,163]	-7	hSpCas9	negative selection	7378317
86658629	86658652	10	-	27260156	MHHES1	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.14474387128754626	[524]	[522,684,554,407]	-3	hSpCas9	negative selection	7442570
86656192	86656215	10	-	27260156	MHHES1	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.07576660866651075	[1589]	[1657,1961,1953,1300]	-1	hSpCas9	negative selection	7442571
86658127	86658150	10	+	27260156	MHHES1	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.4439454550348523	[40]	[27,60,54,0]	-7	hSpCas9	negative selection	7442572
86658566	86658589	10	-	27260156	MEWO	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.49392708635642224	[140]	[198,151,208]	8	hSpCas9	negative selection	7499566
86658074	86658097	10	-	27260156	MEWO	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.015774164819020442	[448]	[445,274,531]	0	hSpCas9	negative selection	7499567
86656274	86656297	10	-	27260156	MEWO	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.7383343432563749	[277]	[167,159,141]	-9	hSpCas9	negative selection	7499568
86658629	86658652	10	-	27260156	MEWO	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.18140129017215967	[524]	[477,433,395]	-4	hSpCas9	negative selection	7563821
86656192	86656215	10	-	27260156	MEWO	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.007080575357192975	[1589]	[1703,1438,1340]	0	hSpCas9	negative selection	7563822
86658127	86658150	10	+	27260156	MEWO	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.09436201076512107	[40]	[41,26,39]	-2	hSpCas9	negative selection	7563823
86658566	86658589	10	-	27260156	LNCAPCLONEFGC	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.9172297153070011	[140]	[267,200,255,243]	9	hSpCas9	negative selection	7620817
86658074	86658097	10	-	27260156	LNCAPCLONEFGC	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.39814734607008917	[448]	[407,547,661,545]	6	hSpCas9	negative selection	7620818
86656274	86656297	10	-	27260156	LNCAPCLONEFGC	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.2558311411636822	[277]	[123,226,317,190]	-4	hSpCas9	negative selection	7620819
86658629	86658652	10	-	27260156	LNCAPCLONEFGC	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.33950392126431017	[524]	[538,605,651,617]	5	hSpCas9	negative selection	7685072
86656192	86656215	10	-	27260156	LNCAPCLONEFGC	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.3015213017299472	[1589]	[1631,1565,2045,1911]	5	hSpCas9	negative selection	7685073
86658127	86658150	10	+	27260156	LNCAPCLONEFGC	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.453204799196687	[40]	[34,22,22,26]	-6	hSpCas9	negative selection	7685074
86658566	86658589	10	-	27260156	PANC0327	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	-0.22453432936816609	[140]	[87,123,97,114]	-3	hSpCas9	negative selection	7742068
86658074	86658097	10	-	27260156	PANC0327	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.3640699843887736	[448]	[560,177,243,293]	-5	hSpCas9	negative selection	7742069
86656274	86656297	10	-	27260156	PANC0327	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.6159547589401622	[277]	[294,147,62,150]	-7	hSpCas9	negative selection	7742070
86658629	86658652	10	-	27260156	PANC0327	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.4186431596297172	[524]	[679,507,714,609]	6	hSpCas9	negative selection	7806323
86656192	86656215	10	-	27260156	PANC0327	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.27548539808248873	[1589]	[1267,1151,1383,873]	-4	hSpCas9	negative selection	7806324
86658127	86658150	10	+	27260156	PANC0327	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.5633110951123479	[40]	[13,52,24,119]	8	hSpCas9	negative selection	7806325
86658566	86658589	10	-	27260156	NCIH2009	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.30310193593040813	[140]	[289,244,202]	4	hSpCas9	negative selection	7863319
86658074	86658097	10	-	27260156	NCIH2009	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.3469599180337257	[448]	[717,824,832]	5	hSpCas9	negative selection	7863320
86656274	86656297	10	-	27260156	NCIH2009	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.7022216874168019	[277]	[272,323,123]	-7	hSpCas9	negative selection	7863321
86658629	86658652	10	-	27260156	NCIH2009	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.08094990537033564	[524]	[922,791,639]	1	hSpCas9	negative selection	7927574
86656192	86656215	10	-	27260156	NCIH2009	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.12551429783462265	[1589]	[1921,1819,2344]	-2	hSpCas9	negative selection	7927575
86658127	86658150	10	+	27260156	NCIH2009	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.08254094344480967	[40]	[39,76,41]	-1	hSpCas9	negative selection	7927576
86658566	86658589	10	-	27260156	NCIH1373	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	1.1991473113943476	[140]	[261,378,217,154]	9	hSpCas9	negative selection	7984570
86658074	86658097	10	-	27260156	NCIH1373	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.07370189287005957	[448]	[541,365,295,252]	0	hSpCas9	negative selection	7984571
86656274	86656297	10	-	27260156	NCIH1373	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.30363413683353246	[277]	[121,287,198,100]	-3	hSpCas9	negative selection	7984572
86658629	86658652	10	-	27260156	NCIH1373	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.2202008398285926	[524]	[542,528,794,229]	2	hSpCas9	negative selection	8048825
86656192	86656215	10	-	27260156	NCIH1373	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.7614354592440702	[1589]	[1456,868,800,306]	-6	hSpCas9	negative selection	8048826
86658127	86658150	10	+	27260156	NCIH1373	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.04068267203908427	[40]	[52,93,20,3]	0	hSpCas9	negative selection	8048827
86658566	86658589	10	-	27260156	PATU8902	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.623877668043819	[140]	[471,102,108,607]	6	hSpCas9	negative selection	8105821
86658074	86658097	10	-	27260156	PATU8902	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.10413475803592126	[448]	[428,609,530,792]	-1	hSpCas9	negative selection	8105822
86656274	86656297	10	-	27260156	PATU8902	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.6655064515462008	[277]	[275,58,252,401]	-6	hSpCas9	negative selection	8105823
86658629	86658652	10	-	27260156	PATU8902	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.014390635202574109	[524]	[407,909,706,962]	0	hSpCas9	negative selection	8170076
86656192	86656215	10	-	27260156	PATU8902	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.9797558557846694	[1589]	[1159,1343,902,1133]	-7	hSpCas9	negative selection	8170077
86658127	86658150	10	+	27260156	PATU8902	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-1.354792753922403	[40]	[59,16,10,0]	-8	hSpCas9	negative selection	8170078
86658566	86658589	10	-	27260156	PANC1	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.21046387691866175	[140]	[160,211,79,121]	3	hSpCas9	negative selection	8227072
86658074	86658097	10	-	27260156	PANC1	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.3910600313981887	[448]	[281,290,243,344]	-6	hSpCas9	negative selection	8227073
86656274	86656297	10	-	27260156	PANC1	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.5918796495523522	[277]	[146,235,205,72]	-7	hSpCas9	negative selection	8227074
86658629	86658652	10	-	27260156	PANC1	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.0960301192807532	[524]	[409,829,433,341]	1	hSpCas9	negative selection	8291327
86656192	86656215	10	-	27260156	PANC1	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.03184189009937133	[1589]	[1184,1503,1652,1064]	0	hSpCas9	negative selection	8291328
86658127	86658150	10	+	27260156	PANC1	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.632563519052725	[40]	[8,73,7,11]	-7	hSpCas9	negative selection	8291329
86658566	86658589	10	-	27260156	PANC0813	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.8624451751236359	[140]	[374,346,302,191]	9	hSpCas9	negative selection	8348323
86658074	86658097	10	-	27260156	PANC0813	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.2650498652944089	[448]	[876,640,378,656]	4	hSpCas9	negative selection	8348324
86656274	86656297	10	-	27260156	PANC0813	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.38314832607251836	[277]	[253,197,200,342]	-5	hSpCas9	negative selection	8348325
86658629	86658652	10	-	27260156	PANC0813	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.08790612223230926	[524]	[607,871,543,594]	1	hSpCas9	negative selection	8412578
86656192	86656215	10	-	27260156	PANC0813	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.06586188343686294	[1589]	[2497,1758,2042,1587]	1	hSpCas9	negative selection	8412579
86658127	86658150	10	+	27260156	PANC0813	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.11844447848719541	[40]	[23,76,22,50]	-2	hSpCas9	negative selection	8412580
86658566	86658589	10	-	27260156	RDES	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.8548480959877011	[140]	[264,205,391,323]	9	hSpCas9	negative selection	8469574
86658074	86658097	10	-	27260156	RDES	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.15485583987833354	[448]	[358,433,577,506]	-3	hSpCas9	negative selection	8469575
86656274	86656297	10	-	27260156	RDES	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.80371487297177	[277]	[166,138,218,215]	-8	hSpCas9	negative selection	8469576
86658629	86658652	10	-	27260156	RDES	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.11637297242744213	[524]	[615,572,744,686]	2	hSpCas9	negative selection	8533829
86656192	86656215	10	-	27260156	RDES	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.13076860830485315	[1589]	[1293,1520,1937,2040]	-2	hSpCas9	negative selection	8533830
86658127	86658150	10	+	27260156	RDES	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.1459063306549746	[40]	[57,30,35,40]	-2	hSpCas9	negative selection	8533831
86658566	86658589	10	-	27260156	PC3	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	-0.08429341921973199	[140]	[93,161,148,131]	-2	hSpCas9	negative selection	8590825
86658074	86658097	10	-	27260156	PC3	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.14219842403918337	[448]	[390,415,778,490]	3	hSpCas9	negative selection	8590826
86656274	86656297	10	-	27260156	PC3	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.5430711192208526	[277]	[50,239,361,224]	-8	hSpCas9	negative selection	8590827
86658629	86658652	10	-	27260156	PC3	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.015365084891276914	[524]	[294,601,697,594]	0	hSpCas9	negative selection	8655080
86656192	86656215	10	-	27260156	PC3	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.15925743325104347	[1589]	[1011,1195,2395,1493]	-4	hSpCas9	negative selection	8655081
86658127	86658150	10	+	27260156	PC3	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.053519976406898095	[40]	[4,84,43,48]	1	hSpCas9	negative selection	8655082
86658566	86658589	10	-	27260156	PATU8988T	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.611930018701164	[140]	[143,241,158,298]	8	hSpCas9	negative selection	8712076
86658074	86658097	10	-	27260156	PATU8988T	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.14876102796212792	[448]	[337,468,382,381]	-3	hSpCas9	negative selection	8712077
86656274	86656297	10	-	27260156	PATU8988T	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	0.06957244348087332	[277]	[217,153,391,355]	1	hSpCas9	negative selection	8712078
86658629	86658652	10	-	27260156	PATU8988T	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.013627370008900241	[524]	[515,535,515,479]	0	hSpCas9	negative selection	8776331
86656192	86656215	10	-	27260156	PATU8988T	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.3087919928238636	[1589]	[1296,1278,1121,1270]	-5	hSpCas9	negative selection	8776332
86658127	86658150	10	+	27260156	PATU8988T	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.20955971325103517	[40]	[31,32,18,102]	3	hSpCas9	negative selection	8776333
86658566	86658589	10	-	27260156	T47D	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.606367784634894	[140]	[234,241,181,345]	9	hSpCas9	negative selection	8833327
86658074	86658097	10	-	27260156	T47D	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.23957562859499168	[448]	[509,323,437,512]	-5	hSpCas9	negative selection	8833328
86656274	86656297	10	-	27260156	T47D	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.49785317634081117	[277]	[235,173,227,285]	-8	hSpCas9	negative selection	8833329
86658629	86658652	10	-	27260156	T47D	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.08598854019847241	[524]	[749,586,633,630]	1	hSpCas9	negative selection	8897582
86656192	86656215	10	-	27260156	T47D	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.35526649823881495	[1589]	[1493,1278,1508,1525]	-6	hSpCas9	negative selection	8897583
86658127	86658150	10	+	27260156	T47D	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.53597729856136	[40]	[26,50,26,24]	-8	hSpCas9	negative selection	8897584
86658566	86658589	10	-	27260156	SU8686	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.6439749554833638	[140]	[213,192,231,240]	9	hSpCas9	negative selection	8954578
86658074	86658097	10	-	27260156	SU8686	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.3386300623529984	[448]	[401,549,583,764]	6	hSpCas9	negative selection	8954579
86656274	86656297	10	-	27260156	SU8686	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.13718931576713733	[277]	[217,252,232,308]	-2	hSpCas9	negative selection	8954580
86658629	86658652	10	-	27260156	SU8686	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.06390237817113409	[524]	[393,512,636,672]	1	hSpCas9	negative selection	9018833
86656192	86656215	10	-	27260156	SU8686	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.15146483435949065	[1589]	[1544,1496,1854,2230]	2	hSpCas9	negative selection	9018834
86658127	86658150	10	+	27260156	SU8686	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.04356106631529055	[40]	[12,40,36,74]	-1	hSpCas9	negative selection	9018835
86658566	86658589	10	-	27260156	SKES1	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.38551533934348825	[140]	[186,212,180,158]	7	hSpCas9	negative selection	9075829
86658074	86658097	10	-	27260156	SKES1	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.15773950443235818	[448]	[716,485,423,406]	3	hSpCas9	negative selection	9075830
86656274	86656297	10	-	27260156	SKES1	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.4441531292101091	[277]	[243,271,178,139]	-7	hSpCas9	negative selection	9075831
86658629	86658652	10	-	27260156	SKES1	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.0719070822754671	[524]	[661,530,380,627]	1	hSpCas9	negative selection	9140084
86656192	86656215	10	-	27260156	SKES1	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.11560295948423582	[1589]	[2384,1657,1449,1479]	2	hSpCas9	negative selection	9140085
86658127	86658150	10	+	27260156	SKES1	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.18313245497178254	[40]	[23,66,18,35]	-4	hSpCas9	negative selection	9140086
86658566	86658589	10	-	27260156	TOV112D	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.4772354490904964	[140]	[165,404,112,151]	8	hSpCas9	negative selection	9197080
86658074	86658097	10	-	27260156	TOV112D	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.32673883963095773	[448]	[276,490,246,441]	-6	hSpCas9	negative selection	9197081
86656274	86656297	10	-	27260156	TOV112D	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.31414700202894363	[277]	[333,334,146,118]	-6	hSpCas9	negative selection	9197082
86658629	86658652	10	-	27260156	TOV112D	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.10118615662745903	[524]	[395,421,544,569]	-2	hSpCas9	negative selection	9261335
86656192	86656215	10	-	27260156	TOV112D	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.020486016737107038	[1589]	[1494,1716,1783,1480]	0	hSpCas9	negative selection	9261336
86658127	86658150	10	+	27260156	TOV112D	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-1.716588597639324	[40]	[4,10,21,10]	-9	hSpCas9	negative selection	9261337
86658566	86658589	10	-	27260156	TC71	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.11971726151103534	[140]	[132,183,137,205]	3	hSpCas9	negative selection	9318331
86658074	86658097	10	-	27260156	TC71	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.18294031707204855	[448]	[562,521,511,591]	4	hSpCas9	negative selection	9318332
86656274	86656297	10	-	27260156	TC71	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.5035264365223808	[277]	[139,201,255,244]	-8	hSpCas9	negative selection	9318333
86658629	86658652	10	-	27260156	TC71	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	-0.2427057018604501	[524]	[467,480,413,545]	-6	hSpCas9	negative selection	9382586
86656192	86656215	10	-	27260156	TC71	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.1549766685973475	[1589]	[1417,1670,1320,1734]	-4	hSpCas9	negative selection	9382587
86658127	86658150	10	+	27260156	TC71	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.19240017035335688	[40]	[49,20,47,33]	-5	hSpCas9	negative selection	9382588
86658566	86658589	10	-	27260156	TC32	viability	CCAGCGGGCGTGTGATTACCAGG	OPN4	ENSG00000122375	0.8069871720554991	[140]	[263,129,353,220]	9	hSpCas9	negative selection	9439582
86658074	86658097	10	-	27260156	TC32	viability	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.13075936466856944	[448]	[310,236,560,514]	-2	hSpCas9	negative selection	9439583
86656274	86656297	10	-	27260156	TC32	viability	AGAAGGTATAGATGACCGTCAGG	OPN4	ENSG00000122375	-0.4501681731245626	[277]	[148,175,258,191]	-7	hSpCas9	negative selection	9439584
86658629	86658652	10	-	27260156	TC32	viability	CATAGAGCCAAACGCCCAGCAGG	OPN4	ENSG00000122375	0.21308563351748597	[524]	[485,509,603,698]	4	hSpCas9	negative selection	9503837
86656192	86656215	10	-	27260156	TC32	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.021349286802745393	[1589]	[1455,1019,1758,1808]	0	hSpCas9	negative selection	9503838
86658127	86658150	10	+	27260156	TC32	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.37700006827355326	[40]	[38,9,51,25]	-6	hSpCas9	negative selection	9503839
86654897	86654920	10	-	27869803	HPAFII	viability after 27 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-0.33333748823006004	[160]	[82,53,NaN]	-3	hSpCas9	negative selection	9538908
86656208	86656231	10	+	27869803	HPAFII	viability after 27 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.6868258242379348	[296]	[126,71,NaN]	-5	hSpCas9	negative selection	9538909
86658074	86658097	10	-	27869803	HPAFII	viability after 27 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.0112706023785909	[343]	[118,234,NaN]	0	hSpCas9	negative selection	9538910
86658672	86658695	10	-	27869803	HPAFII	viability after 27 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.2958286779678039	[291]	[110,252,NaN]	2	hSpCas9	negative selection	9538911
86659356	86659379	10	-	27869803	HPAFII	viability after 27 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.4430162251629315	[151]	[208,24,NaN]	3	hSpCas9	negative selection	9538912
86660050	86660073	10	-	27869803	HPAFII	viability after 27 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.6588591806325672	[512]	[673,218,NaN]	5	hSpCas9	negative selection	9538913
86654897	86654920	10	-	27869803	HPAFII	viability after 15 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-0.5844005832544175	[160]	[107,119,NaN]	-6	hSpCas9	negative selection	9621357
86656208	86656231	10	+	27869803	HPAFII	viability after 15 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.6628859455807332	[296]	[282,150,NaN]	-6	hSpCas9	negative selection	9621358
86658074	86658097	10	-	27869803	HPAFII	viability after 15 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.2093090185035854	[343]	[403,441,NaN]	2	hSpCas9	negative selection	9621359
86658672	86658695	10	-	27869803	HPAFII	viability after 15 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	-0.3075447113535807	[291]	[313,215,NaN]	-3	hSpCas9	negative selection	9621360
86659356	86659379	10	-	27869803	HPAFII	viability after 15 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.5244307468174362	[151]	[443,104,NaN]	6	hSpCas9	negative selection	9621361
86660050	86660073	10	-	27869803	HPAFII	viability after 15 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.6786458388496026	[512]	[1294,625,NaN]	7	hSpCas9	negative selection	9621362
86654897	86654920	10	-	27869803	ASPC1	viability after 36 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-0.6352321593938024	[282]	[88,30,70]	-6	hSpCas9	negative selection	9703806
86656208	86656231	10	+	27869803	ASPC1	viability after 36 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	1.3929280812773128	[806]	[2099,125,264]	9	hSpCas9	negative selection	9703807
86658074	86658097	10	-	27869803	ASPC1	viability after 36 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.5893512753874388	[847]	[884,286,257]	6	hSpCas9	negative selection	9703808
86658672	86658695	10	-	27869803	ASPC1	viability after 36 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	-0.15063917354396308	[824]	[298,276,214]	-1	hSpCas9	negative selection	9703809
86659356	86659379	10	-	27869803	ASPC1	viability after 36 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.5803314179520652	[700]	[200,561,321]	6	hSpCas9	negative selection	9703810
86660050	86660073	10	-	27869803	ASPC1	viability after 36 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.7239189867584754	[1572]	[896,992,835]	7	hSpCas9	negative selection	9703811
86654897	86654920	10	-	27869803	PATU8988S	viability after 35 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	0.7001167709515712	[314]	[254,156,NaN]	7	hSpCas9	negative selection	9786255
86656208	86656231	10	+	27869803	PATU8988S	viability after 35 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.0388707984374671	[764]	[261,337,NaN]	0	hSpCas9	negative selection	9786256
86658074	86658097	10	-	27869803	PATU8988S	viability after 35 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.48933921583635204	[651]	[424,311,NaN]	5	hSpCas9	negative selection	9786257
86658672	86658695	10	-	27869803	PATU8988S	viability after 35 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.422291635542402	[641]	[342,349,NaN]	5	hSpCas9	negative selection	9786258
86659356	86659379	10	-	27869803	PATU8988S	viability after 35 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.23110998175639821	[458]	[156,157,NaN]	-2	hSpCas9	negative selection	9786259
86660050	86660073	10	-	27869803	PATU8988S	viability after 35 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-0.055281960966848676	[1351]	[544,502,NaN]	0	hSpCas9	negative selection	9786260
86654897	86654920	10	-	27869803	PATU8988S	viability after 31 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-0.4040565169989103	[314]	[108,76,NaN]	-4	hSpCas9	negative selection	9868704
86656208	86656231	10	+	27869803	PATU8988S	viability after 31 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.04112044545100263	[764]	[233,375,NaN]	0	hSpCas9	negative selection	9868705
86658074	86658097	10	-	27869803	PATU8988S	viability after 31 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	0.5794382484398104	[651]	[391,383,NaN]	7	hSpCas9	negative selection	9868706
86658672	86658695	10	-	27869803	PATU8988S	viability after 31 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.4254843727924599	[641]	[367,312,NaN]	5	hSpCas9	negative selection	9868707
86659356	86659379	10	-	27869803	PATU8988S	viability after 31 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	0.11515776015170665	[458]	[155,251,NaN]	1	hSpCas9	negative selection	9868708
86660050	86660073	10	-	27869803	PATU8988S	viability after 31 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	-0.09432449255675479	[1351]	[416,616,NaN]	-1	hSpCas9	negative selection	9868709
86654897	86654920	10	-	27869803	HPAFII	viability after 35 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-0.028112489190032397	[160]	[62,98,NaN]	0	hSpCas9	negative selection	9951153
86656208	86656231	10	+	27869803	HPAFII	viability after 35 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.7242479502278709	[296]	[114,63,NaN]	-4	hSpCas9	negative selection	9951154
86658074	86658097	10	-	27869803	HPAFII	viability after 35 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.20297963533165697	[343]	[28,288,NaN]	-1	hSpCas9	negative selection	9951155
86658672	86658695	10	-	27869803	HPAFII	viability after 35 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.791729299549704	[291]	[182,337,NaN]	5	hSpCas9	negative selection	9951156
86659356	86659379	10	-	27869803	HPAFII	viability after 35 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.08361146692027677	[151]	[129,7,NaN]	0	hSpCas9	negative selection	9951157
86660050	86660073	10	-	27869803	HPAFII	viability after 35 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.782166604462291	[512]	[622,247,NaN]	5	hSpCas9	negative selection	9951158
86654897	86654920	10	-	27869803	HPAFII	viability after 31 days	TGATGGATGGAAGCCGGCCCAGG	OPN4	ENSG00000122375	-0.5025458004177248	[160]	[69,56,NaN]	-3	hSpCas9	negative selection	10033602
86656208	86656231	10	+	27869803	HPAFII	viability after 31 days	AGACCATGCCCACTATACCCTGG	OPN4	ENSG00000122375	-0.3388977422353538	[296]	[126,136,NaN]	-2	hSpCas9	negative selection	10033603
86658074	86658097	10	-	27869803	HPAFII	viability after 31 days	TGAGGAAGTCGCTGACCGCGAGG	OPN4	ENSG00000122375	-0.17148990013430815	[343]	[57,294,NaN]	-1	hSpCas9	negative selection	10033604
86658672	86658695	10	-	27869803	HPAFII	viability after 31 days	CACTTACTCCAGCCGAAGAAGGG	OPN4	ENSG00000122375	0.3220210274395413	[291]	[156,256,NaN]	2	hSpCas9	negative selection	10033605
86659356	86659379	10	-	27869803	HPAFII	viability after 31 days	ATGGTGTAGGCACGCACGGCCGG	OPN4	ENSG00000122375	-0.0005657922634910717	[151]	[135,29,NaN]	0	hSpCas9	negative selection	10033606
86660050	86660073	10	-	27869803	HPAFII	viability after 31 days	AGCCACTGCTTACCCAGCAAAGG	OPN4	ENSG00000122375	0.5656044253590606	[512]	[539,301,NaN]	4	hSpCas9	negative selection	10033607
86656192	86656215	10	-	28162770	P31FUJ	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.4695172469449363	[117]	[191]	5	hSpCas9	negative selection	10204887
86661337	86661360	10	-	28162770	P31FUJ	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-0.8044867101475185	[702]	[472]	-6	hSpCas9	negative selection	10204888
86654884	86654907	10	+	28162770	P31FUJ	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-0.5357887356482808	[226]	[183]	-4	hSpCas9	negative selection	10204889
86656229	86656252	10	+	28162770	P31FUJ	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	-0.013792422472582722	[365]	[425]	0	hSpCas9	negative selection	10204890
86658112	86658135	10	-	28162770	P31FUJ	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.20306879828163082	[274]	[371]	2	hSpCas9	negative selection	10204891
86658127	86658150	10	+	28162770	P31FUJ	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	1.013358382855019	[128]	[305]	9	hSpCas9	negative selection	10204892
86659337	86659360	10	+	28162770	P31FUJ	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	0.16038457364280556	[315]	[414]	1	hSpCas9	negative selection	10204893
86659369	86659392	10	-	28162770	P31FUJ	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-0.6062605999418229	[113]	[87]	-5	hSpCas9	negative selection	10204894
86659407	86659430	10	-	28162770	P31FUJ	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	-0.5007354096610119	[176]	[146]	-4	hSpCas9	negative selection	10204895
86660003	86660026	10	-	28162770	P31FUJ	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.3041868376511442	[144]	[137]	-3	hSpCas9	negative selection	10204896
86656192	86656215	10	-	28162770	TF1	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10374253
86661337	86661360	10	-	28162770	TF1	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	NaN	[NaN]	[149]	1	hSpCas9	negative selection	10374254
86654884	86654907	10	+	28162770	TF1	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	NaN	[NaN]	[168]	1	hSpCas9	negative selection	10374255
86656229	86656252	10	+	28162770	TF1	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	NaN	[NaN]	[249]	1	hSpCas9	negative selection	10374256
86658112	86658135	10	-	28162770	TF1	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10374257
86658127	86658150	10	+	28162770	TF1	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10374258
86659337	86659360	10	+	28162770	TF1	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	NaN	[NaN]	[202]	1	hSpCas9	negative selection	10374259
86659369	86659392	10	-	28162770	TF1	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10374260
86659407	86659430	10	-	28162770	TF1	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10374261
86660003	86660026	10	-	28162770	TF1	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	NaN	[NaN]	[9]	1	hSpCas9	negative selection	10374262
86656192	86656215	10	-	28162770	SKM1	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.25168597326525066	[32]	[48]	-2	hSpCas9	negative selection	10543619
86661337	86661360	10	-	28162770	SKM1	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-0.7065244806020694	[167]	[181]	-5	hSpCas9	negative selection	10543620
86654884	86654907	10	+	28162770	SKM1	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	0.37354911109580113	[61]	[141]	3	hSpCas9	negative selection	10543621
86656229	86656252	10	+	28162770	SKM1	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	0.10535300014622861	[111]	[212]	1	hSpCas9	negative selection	10543622
86658112	86658135	10	-	28162770	SKM1	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.05412664381582599	[78]	[144]	0	hSpCas9	negative selection	10543623
86658127	86658150	10	+	28162770	SKM1	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	1.2966427984766136	[34]	[151]	9	hSpCas9	negative selection	10543624
86659337	86659360	10	+	28162770	SKM1	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	-0.5145731728297582	[79]	[98]	-4	hSpCas9	negative selection	10543625
86659369	86659392	10	-	28162770	SKM1	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-1.0850361038557992	[29]	[24]	-7	hSpCas9	negative selection	10543626
86659407	86659430	10	-	28162770	SKM1	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	1.2876227931524926	[18]	[81]	9	hSpCas9	negative selection	10543627
86660003	86660026	10	-	28162770	SKM1	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.23703919730084955	[35]	[53]	-2	hSpCas9	negative selection	10543628
86656192	86656215	10	-	28162770	SKM1	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.25168597326525066	[32]	[48]	-2	hSpCas9	negative selection	10712985
86661337	86661360	10	-	28162770	SKM1	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-0.7065244806020694	[167]	[181]	-5	hSpCas9	negative selection	10712986
86654884	86654907	10	+	28162770	SKM1	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	0.37354911109580113	[61]	[141]	3	hSpCas9	negative selection	10712987
86656229	86656252	10	+	28162770	SKM1	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	0.10535300014622861	[111]	[212]	1	hSpCas9	negative selection	10712988
86658112	86658135	10	-	28162770	SKM1	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.05412664381582599	[78]	[144]	0	hSpCas9	negative selection	10712989
86658127	86658150	10	+	28162770	SKM1	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	1.2966427984766136	[34]	[151]	9	hSpCas9	negative selection	10712990
86659337	86659360	10	+	28162770	SKM1	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	-0.5145731728297582	[79]	[98]	-4	hSpCas9	negative selection	10712991
86659369	86659392	10	-	28162770	SKM1	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-1.0850361038557992	[29]	[24]	-7	hSpCas9	negative selection	10712992
86659407	86659430	10	-	28162770	SKM1	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	1.2876227931524926	[18]	[81]	9	hSpCas9	negative selection	10712993
86660003	86660026	10	-	28162770	SKM1	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.23703919730084955	[35]	[53]	-2	hSpCas9	negative selection	10712994
86656192	86656215	10	-	28162770	PL21	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.43350315364677117	[130]	[76]	4	hSpCas9	negative selection	10882351
86661337	86661360	10	-	28162770	PL21	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	0.1151644854667282	[506]	[238]	1	hSpCas9	negative selection	10882352
86654884	86654907	10	+	28162770	PL21	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-1.0799683047034152	[339]	[69]	-6	hSpCas9	negative selection	10882353
86656229	86656252	10	+	28162770	PL21	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	1.0485172295940155	[420]	[378]	8	hSpCas9	negative selection	10882354
86658112	86658135	10	-	28162770	PL21	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.4015549020594481	[286]	[164]	3	hSpCas9	negative selection	10882355
86658127	86658150	10	+	28162770	PL21	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.2781421264905933	[179]	[94]	2	hSpCas9	negative selection	10882356
86659337	86659360	10	+	28162770	PL21	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	0.7283877242161547	[293]	[211]	6	hSpCas9	negative selection	10882357
86659369	86659392	10	-	28162770	PL21	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	0.21828696119957947	[78]	[39]	2	hSpCas9	negative selection	10882358
86659407	86659430	10	-	28162770	PL21	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	0.9151626557748495	[105]	[86]	7	hSpCas9	negative selection	10882359
86660003	86660026	10	-	28162770	PL21	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.7833722627221108	[173]	[43]	-5	hSpCas9	negative selection	10882360
86656192	86656215	10	-	28162770	P31FUJ	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.4695172469449363	[117]	[191]	5	hSpCas9	negative selection	11051717
86661337	86661360	10	-	28162770	P31FUJ	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-0.8044867101475185	[702]	[472]	-6	hSpCas9	negative selection	11051718
86654884	86654907	10	+	28162770	P31FUJ	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-0.5357887356482808	[226]	[183]	-4	hSpCas9	negative selection	11051719
86656229	86656252	10	+	28162770	P31FUJ	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	-0.013792422472582722	[365]	[425]	0	hSpCas9	negative selection	11051720
86658112	86658135	10	-	28162770	P31FUJ	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.20306879828163082	[274]	[371]	2	hSpCas9	negative selection	11051721
86658127	86658150	10	+	28162770	P31FUJ	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	1.013358382855019	[128]	[305]	9	hSpCas9	negative selection	11051722
86659337	86659360	10	+	28162770	P31FUJ	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	0.16038457364280556	[315]	[414]	1	hSpCas9	negative selection	11051723
86659369	86659392	10	-	28162770	P31FUJ	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-0.6062605999418229	[113]	[87]	-5	hSpCas9	negative selection	11051724
86659407	86659430	10	-	28162770	P31FUJ	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	-0.5007354096610119	[176]	[146]	-4	hSpCas9	negative selection	11051725
86660003	86660026	10	-	28162770	P31FUJ	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.3041868376511442	[144]	[137]	-3	hSpCas9	negative selection	11051726
86656192	86656215	10	-	28162770	OCIAML5	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.5741981838381008	[47]	[128]	5	hSpCas9	negative selection	11221083
86661337	86661360	10	-	28162770	OCIAML5	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-0.3831360635899512	[288]	[399]	-3	hSpCas9	negative selection	11221084
86654884	86654907	10	+	28162770	OCIAML5	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-0.1516268527229048	[143]	[233]	-1	hSpCas9	negative selection	11221085
86656229	86656252	10	+	28162770	OCIAML5	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	0.8144612820132366	[148]	[472]	7	hSpCas9	negative selection	11221086
86658112	86658135	10	-	28162770	OCIAML5	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	-0.12508506527041308	[173]	[287]	-1	hSpCas9	negative selection	11221087
86658127	86658150	10	+	28162770	OCIAML5	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	1.7973634637353195	[61]	[388]	9	hSpCas9	negative selection	11221088
86659337	86659360	10	+	28162770	OCIAML5	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	0.351375556731091	[207]	[478]	3	hSpCas9	negative selection	11221089
86659369	86659392	10	-	28162770	OCIAML5	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-0.7347096202258383	[58]	[63]	-5	hSpCas9	negative selection	11221090
86659407	86659430	10	-	28162770	OCIAML5	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	0.11690653351537858	[93]	[183]	1	hSpCas9	negative selection	11221091
86660003	86660026	10	-	28162770	OCIAML5	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	0.5264450523897329	[49]	[129]	4	hSpCas9	negative selection	11221092
86656192	86656215	10	-	28162770	EOL1	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	-0.044291296943004876	[228]	[116]	0	hSpCas9	negative selection	11390449
86661337	86661360	10	-	28162770	EOL1	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	0.4190386811690132	[679]	[478]	4	hSpCas9	negative selection	11390450
86654884	86654907	10	+	28162770	EOL1	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-0.6966901155421714	[442]	[143]	-5	hSpCas9	negative selection	11390451
86656229	86656252	10	+	28162770	EOL1	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	0.6082283232415833	[705]	[566]	5	hSpCas9	negative selection	11390452
86658112	86658135	10	-	28162770	EOL1	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	-0.5697164188588844	[523]	[185]	-4	hSpCas9	negative selection	11390453
86658127	86658150	10	+	28162770	EOL1	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.009564292773008368	[320]	[167]	0	hSpCas9	negative selection	11390454
86659337	86659360	10	+	28162770	EOL1	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	0.6615133657367408	[353]	[294]	6	hSpCas9	negative selection	11390455
86659369	86659392	10	-	28162770	EOL1	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-0.8512370714861999	[112]	[32]	-5	hSpCas9	negative selection	11390456
86659407	86659430	10	-	28162770	EOL1	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	-0.06357812814117358	[120]	[60]	0	hSpCas9	negative selection	11390457
86660003	86660026	10	-	28162770	EOL1	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.409189625606461	[183]	[72]	-3	hSpCas9	negative selection	11390458
86656192	86656215	10	-	28162770	MOLM13	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.03993599438044937	[186]	[138]	0	hSpCas9	negative selection	11559815
86661337	86661360	10	-	28162770	MOLM13	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	0.27244385942122795	[662]	[578]	2	hSpCas9	negative selection	11559816
86654884	86654907	10	+	28162770	MOLM13	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-0.03734592670584319	[351]	[247]	0	hSpCas9	negative selection	11559817
86656229	86656252	10	+	28162770	MOLM13	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	1.1568496027999524	[494]	[797]	8	hSpCas9	negative selection	11559818
86658112	86658135	10	-	28162770	MOLM13	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.15293084147205815	[412]	[331]	1	hSpCas9	negative selection	11559819
86658127	86658150	10	+	28162770	MOLM13	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.7850004601341654	[239]	[298]	6	hSpCas9	negative selection	11559820
86659337	86659360	10	+	28162770	MOLM13	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	-0.2313028699897024	[577]	[355]	-1	hSpCas9	negative selection	11559821
86659369	86659392	10	-	28162770	MOLM13	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-1.2651717581657114	[122]	[36]	-6	hSpCas9	negative selection	11559822
86659407	86659430	10	-	28162770	MOLM13	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	-0.7185237426863025	[131]	[57]	-4	hSpCas9	negative selection	11559823
86660003	86660026	10	-	28162770	MOLM13	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-1.3328018102320147	[215]	[61]	-6	hSpCas9	negative selection	11559824
86656192	86656215	10	-	28162770	HEL	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.2721759618621181	[180]	[139]	2	hSpCas9	negative selection	11729181
86661337	86661360	10	-	28162770	HEL	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-1.060729850177762	[595]	[182]	-6	hSpCas9	negative selection	11729182
86654884	86654907	10	+	28162770	HEL	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-0.11983740584488689	[340]	[200]	-1	hSpCas9	negative selection	11729183
86656229	86656252	10	+	28162770	HEL	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	1.0686412188707228	[462]	[621]	8	hSpCas9	negative selection	11729184
86658112	86658135	10	-	28162770	HEL	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	-0.01234975511144143	[410]	[260]	0	hSpCas9	negative selection	11729185
86658127	86658150	10	+	28162770	HEL	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.31103815123899736	[214]	[110]	-2	hSpCas9	negative selection	11729186
86659337	86659360	10	+	28162770	HEL	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	-0.30176605540793944	[407]	[211]	-2	hSpCas9	negative selection	11729187
86659369	86659392	10	-	28162770	HEL	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-3.2853682495178576	[136]	[8]	-9	hSpCas9	negative selection	11729188
86659407	86659430	10	-	28162770	HEL	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	0.12672368499669207	[142]	[99]	1	hSpCas9	negative selection	11729189
86660003	86660026	10	-	28162770	HEL	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.37895623909896214	[133]	[65]	-3	hSpCas9	negative selection	11729190
86656192	86656215	10	-	28162770	MV411	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.40721799481954457	[110]	[123]	3	hSpCas9	negative selection	11898547
86661337	86661360	10	-	28162770	MV411	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-0.3512868511828655	[473]	[312]	-3	hSpCas9	negative selection	11898548
86654884	86654907	10	+	28162770	MV411	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-0.21003521481646514	[183]	[133]	-2	hSpCas9	negative selection	11898549
86656229	86656252	10	+	28162770	MV411	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	0.5855423898267551	[336]	[425]	5	hSpCas9	negative selection	11898550
86658112	86658135	10	-	28162770	MV411	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.12630111328114046	[297]	[273]	1	hSpCas9	negative selection	11898551
86658127	86658150	10	+	28162770	MV411	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.24769353970931526	[178]	[126]	-2	hSpCas9	negative selection	11898552
86659337	86659360	10	+	28162770	MV411	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	0.2723551829871047	[286]	[291]	2	hSpCas9	negative selection	11898553
86659369	86659392	10	-	28162770	MV411	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-0.10722733051658673	[77]	[60]	-1	hSpCas9	negative selection	11898554
86659407	86659430	10	-	28162770	MV411	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	-0.7865097811405625	[128]	[62]	-5	hSpCas9	negative selection	11898555
86660003	86660026	10	-	28162770	MV411	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.03918367536863454	[110]	[90]	0	hSpCas9	negative selection	11898556
86656192	86656215	10	-	28162770	MONOMAC1	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.41301663462443283	[75]	[115]	4	hSpCas9	negative selection	12067913
86661337	86661360	10	-	28162770	MONOMAC1	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-1.338764956671214	[341]	[154]	-7	hSpCas9	negative selection	12067914
86654884	86654907	10	+	28162770	MONOMAC1	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-0.736063063613851	[169]	[116]	-6	hSpCas9	negative selection	12067915
86656229	86656252	10	+	28162770	MONOMAC1	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	0.18590702250943658	[249]	[325]	2	hSpCas9	negative selection	12067916
86658112	86658135	10	-	28162770	MONOMAC1	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	0.0242530178297361	[186]	[217]	0	hSpCas9	negative selection	12067917
86658127	86658150	10	+	28162770	MONOMAC1	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	-0.11686649837557028	[104]	[110]	-1	hSpCas9	negative selection	12067918
86659337	86659360	10	+	28162770	MONOMAC1	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	-0.39426919449760145	[179]	[156]	-3	hSpCas9	negative selection	12067919
86659369	86659392	10	-	28162770	MONOMAC1	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-1.4358237066466704	[58]	[24]	-8	hSpCas9	negative selection	12067920
86659407	86659430	10	-	28162770	MONOMAC1	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	0.9828722429553807	[63]	[144]	8	hSpCas9	negative selection	12067921
86660003	86660026	10	-	28162770	MONOMAC1	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.32536094403509325	[93]	[85]	-3	hSpCas9	negative selection	12067922
86656192	86656215	10	-	28162770	OCIAML2	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.8280284903223538	[24]	[245]	7	hSpCas9	negative selection	12237279
86661337	86661360	10	-	28162770	OCIAML2	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-0.6283112309297266	[98]	[354]	-5	hSpCas9	negative selection	12237280
86654884	86654907	10	+	28162770	OCIAML2	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	0.19722568382733982	[30]	[196]	2	hSpCas9	negative selection	12237281
86656229	86656252	10	+	28162770	OCIAML2	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	0.4714025764866143	[72]	[560]	4	hSpCas9	negative selection	12237282
86658112	86658135	10	-	28162770	OCIAML2	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	-0.2257427661186267	[49]	[236]	-2	hSpCas9	negative selection	12237283
86658127	86658150	10	+	28162770	OCIAML2	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.5443205162238103	[23]	[193]	5	hSpCas9	negative selection	12237284
86659337	86659360	10	+	28162770	OCIAML2	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	-0.06521674485171741	[46]	[248]	0	hSpCas9	negative selection	12237285
86659369	86659392	10	-	28162770	OCIAML2	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-0.8135175387651699	[12]	[40]	-5	hSpCas9	negative selection	12237286
86659407	86659430	10	-	28162770	OCIAML2	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	0.699295176200151	[13]	[125]	6	hSpCas9	negative selection	12237287
86660003	86660026	10	-	28162770	OCIAML2	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-0.07831240246340099	[19]	[104]	0	hSpCas9	negative selection	12237288
86656192	86656215	10	-	28162770	OCIAML3	viability	ATGGTCTGGAACATCAACCGTGG	OPN4	ENSG00000122375	0.7624776765995677	[32]	[168]	6	hSpCas9	negative selection	12406645
86661337	86661360	10	-	28162770	OCIAML3	viability	GATGGGGTTGTGGATTGCAGAGG	OPN4	ENSG00000122375	-0.20077451136366786	[149]	[393]	-1	hSpCas9	negative selection	12406646
86654884	86654907	10	+	28162770	OCIAML3	viability	GCAGCATCTCCAGCCTGGGCCGG	OPN4	ENSG00000122375	-0.4519886354517354	[86]	[191]	-3	hSpCas9	negative selection	12406647
86656229	86656252	10	+	28162770	OCIAML3	viability	GGGCACAGTGATCTTGCTGGTGG	OPN4	ENSG00000122375	0.6825964640537089	[96]	[469]	6	hSpCas9	negative selection	12406648
86658112	86658135	10	-	28162770	OCIAML3	viability	GCTACTGGTGAAGAAGACAGGGG	OPN4	ENSG00000122375	-1.2720795454368008	[103]	[129]	-7	hSpCas9	negative selection	12406649
86658127	86658150	10	+	28162770	OCIAML3	viability	CCAGTAGCCTCTATAAGCAGTGG	OPN4	ENSG00000122375	0.8389517669519431	[49]	[269]	7	hSpCas9	negative selection	12406650
86659337	86659360	10	+	28162770	OCIAML3	viability	GGACTACATGAGCTTCACGCCGG	OPN4	ENSG00000122375	0.21588947629589395	[80]	[283]	2	hSpCas9	negative selection	12406651
86659369	86659392	10	-	28162770	OCIAML3	viability	GCAGCAGAGAAGCATGGTGTAGG	OPN4	ENSG00000122375	-1.9476445949388639	[22]	[17]	-8	hSpCas9	negative selection	12406652
86659407	86659430	10	-	28162770	OCIAML3	viability	CAGTAGATGATGATAAGCAGAGG	OPN4	ENSG00000122375	0.11381160818252667	[29]	[97]	1	hSpCas9	negative selection	12406653
86660003	86660026	10	-	28162770	OCIAML3	viability	GAGCCCAGGAGAGCACGAAGAGG	OPN4	ENSG00000122375	-1.7866527182665592	[31]	[27]	-8	hSpCas9	negative selection	12406654