Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:221391
• Symbol:OPN5
• Description:opsin 5

DataSource: http://genomecrispr.dkfz.de/#!/results/OPN5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
47791842	47791865	6	-	26472758	Jiyoye	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	1.8121592161207944	[53]	[142]	8	hSpCas9	negative selection	113906
47795542	47795565	6	+	26472758	Jiyoye	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	-0.6401303332724833	[30]	[14]	-4	hSpCas9	negative selection	113907
47795438	47795461	6	-	26472758	Jiyoye	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.16431885760970988	[70]	[59]	1	hSpCas9	negative selection	113908
47791869	47791892	6	-	26472758	Jiyoye	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	2.151336477076284	[79]	[267]	9	hSpCas9	negative selection	113909
47795280	47795303	6	-	26472758	Jiyoye	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.17124620583467765	[231]	[196]	1	hSpCas9	negative selection	113910
47795395	47795418	6	-	26472758	Jiyoye	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	1.0809471491848854	[125]	[200]	7	hSpCas9	negative selection	113911
47808268	47808291	6	-	26472758	Jiyoye	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	0.736880826984955	[73]	[92]	5	hSpCas9	negative selection	113912
47795298	47795321	6	-	26472758	Jiyoye	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	-0.1047236570255593	[76]	[53]	0	hSpCas9	negative selection	113913
47795340	47795363	6	-	26472758	Jiyoye	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	1.9779240230073287	[67]	[201]	8	hSpCas9	negative selection	113914
47795524	47795547	6	+	26472758	Jiyoye	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	-0.1777871192152829	[23]	[15]	-1	hSpCas9	negative selection	113915
47791842	47791865	6	-	26472758	KBM7	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.772441177809395	[352,274]	[198,295]	8	hSpCas9	negative selection	305024
47795542	47795565	6	+	26472758	KBM7	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	-0.41383828204238116	[100,111]	[47,28]	-4	hSpCas9	negative selection	305025
47795438	47795461	6	-	26472758	KBM7	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.2598927616366677	[298,285]	[266,73]	2	hSpCas9	negative selection	305026
47791869	47791892	6	-	26472758	KBM7	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.2493529732143157	[771,772]	[388,473]	2	hSpCas9	negative selection	305027
47795280	47795303	6	-	26472758	KBM7	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.33811449609480215	[666,696]	[516,310]	3	hSpCas9	negative selection	305028
47795395	47795418	6	-	26472758	KBM7	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.6919711894137555	[607,489]	[622,227]	7	hSpCas9	negative selection	305029
47808268	47808291	6	-	26472758	KBM7	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	-0.2193996232341182	[430,277]	[117,160]	-2	hSpCas9	negative selection	305030
47795298	47795321	6	-	26472758	KBM7	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	1.1814898800975993	[312,350]	[388,329]	9	hSpCas9	negative selection	305031
47795340	47795363	6	-	26472758	KBM7	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.7112054076815515	[916,785]	[511,779]	7	hSpCas9	negative selection	305032
47795524	47795547	6	+	26472758	KBM7	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	-0.799645552573419	[93,68]	[25,17]	-6	hSpCas9	negative selection	305033
47791842	47791865	6	-	26472758	Raji	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.6309454914306123	[127]	[45]	6	hSpCas9	negative selection	496142
47795542	47795565	6	+	26472758	Raji	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	-0.6439373517696769	[100]	[14]	-5	hSpCas9	negative selection	496143
47795438	47795461	6	-	26472758	Raji	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.9781005184286329	[69]	[31]	8	hSpCas9	negative selection	496144
47791869	47791892	6	-	26472758	Raji	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.7052850918022537	[295]	[111]	6	hSpCas9	negative selection	496145
47795280	47795303	6	-	26472758	Raji	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	1.042730577031346	[250]	[119]	8	hSpCas9	negative selection	496146
47795395	47795418	6	-	26472758	Raji	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.4000244032927167	[208]	[63]	4	hSpCas9	negative selection	496147
47808268	47808291	6	-	26472758	Raji	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	0.7150661125948391	[146]	[55]	6	hSpCas9	negative selection	496148
47795298	47795321	6	-	26472758	Raji	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.5782742693859607	[227]	[78]	5	hSpCas9	negative selection	496149
47795340	47795363	6	-	26472758	Raji	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.13881604321025653	[453]	[115]	1	hSpCas9	negative selection	496150
47795524	47795547	6	+	26472758	Raji	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	2.3138344128410253	[12]	[14]	9	hSpCas9	negative selection	496151
47791842	47791865	6	-	26472758	K562	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.9675121472510956	[208]	[344]	7	hSpCas9	negative selection	687260
47795542	47795565	6	+	26472758	K562	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	0.8405217859928036	[85]	[129]	7	hSpCas9	negative selection	687261
47795438	47795461	6	-	26472758	K562	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.19583854722138505	[301]	[291]	1	hSpCas9	negative selection	687262
47791869	47791892	6	-	26472758	K562	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	-0.33771218227154676	[508]	[339]	-2	hSpCas9	negative selection	687263
47795280	47795303	6	-	26472758	K562	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.36677635936297215	[530]	[577]	3	hSpCas9	negative selection	687264
47795395	47795418	6	-	26472758	K562	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	1.2325166386101554	[425]	[844]	9	hSpCas9	negative selection	687265
47808268	47808291	6	-	26472758	K562	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	-0.29691684065445123	[341]	[234]	-2	hSpCas9	negative selection	687266
47795298	47795321	6	-	26472758	K562	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.5328227884142736	[356]	[435]	4	hSpCas9	negative selection	687267
47795340	47795363	6	-	26472758	K562	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.9635867787370571	[782]	[1288]	7	hSpCas9	negative selection	687268
47795524	47795547	6	+	26472758	K562	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	-1.2674803108649861	[153]	[53]	-6	hSpCas9	negative selection	687269
47782086	47782109	6	-	26627737	DLD1	viability	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.13418544853078734	[320]	[222,66,47]	1	hSpCas9	negative selection	833311
47791842	47791865	6	-	26627737	DLD1	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.24284045318833059	[853]	[151,409,379]	2	hSpCas9	negative selection	833312
47795341	47795364	6	+	26627737	DLD1	viability	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.18482453193735005	[673]	[324,251,154]	2	hSpCas9	negative selection	833313
47795428	47795451	6	-	26627737	DLD1	viability	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-0.27579490995239153	[1147]	[231,344,311]	-3	hSpCas9	negative selection	833314
47808242	47808265	6	-	26627737	DLD1	viability	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	1.2809427504183593	[84]	[92,84,22]	9	hSpCas9	negative selection	833315
47808338	47808361	6	-	26627737	DLD1	viability	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	0.12897858568359366	[1063]	[375,434,293]	1	hSpCas9	negative selection	833316
47782086	47782109	6	-	26627737	GBM cells	viability after 5 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.2629370045157117	[244]	[99,118]	-4	hSpCas9	negative selection	915626
47791842	47791865	6	-	26627737	GBM cells	viability after 5 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.055571465861945835	[467]	[205,276]	-1	hSpCas9	negative selection	915627
47795341	47795364	6	+	26627737	GBM cells	viability after 5 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.3431323995764756	[207]	[140,141]	5	hSpCas9	negative selection	915628
47795428	47795451	6	-	26627737	GBM cells	viability after 5 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	0.003318587958335617	[492]	[252,276]	0	hSpCas9	negative selection	915629
47808242	47808265	6	-	26627737	GBM cells	viability after 5 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.9790842235696691	[104]	[134,86]	9	hSpCas9	negative selection	915630
47808338	47808361	6	-	26627737	GBM cells	viability after 5 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	0.4137844799484095	[484]	[350,341]	6	hSpCas9	negative selection	915631
47782086	47782109	6	-	26627737	GBM cells	viability after 13 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.63929014251009	[244]	[86,83]	-6	hSpCas9	negative selection	997941
47791842	47791865	6	-	26627737	GBM cells	viability after 13 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.034108060654506	[467]	[306,199]	0	hSpCas9	negative selection	997942
47795341	47795364	6	+	26627737	GBM cells	viability after 13 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.7519655994523797	[207]	[242,146]	8	hSpCas9	negative selection	997943
47795428	47795451	6	-	26627737	GBM cells	viability after 13 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-0.13512716753670817	[492]	[290,204]	-2	hSpCas9	negative selection	997944
47808242	47808265	6	-	26627737	GBM cells	viability after 13 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.96122184069605	[104]	[159,70]	9	hSpCas9	negative selection	997945
47808338	47808361	6	-	26627737	GBM cells	viability after 13 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	-0.17801228446013728	[484]	[193,263]	-2	hSpCas9	negative selection	997946
47782086	47782109	6	-	26627737	GBM cells	viability after 21 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.11702132364552428	[244]	[128,116]	-1	hSpCas9	negative selection	1080256
47791842	47791865	6	-	26627737	GBM cells	viability after 21 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.47466389037105805	[467]	[392,316]	5	hSpCas9	negative selection	1080257
47795341	47795364	6	+	26627737	GBM cells	viability after 21 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.8148062520841619	[207]	[203,193]	7	hSpCas9	negative selection	1080258
47795428	47795451	6	-	26627737	GBM cells	viability after 21 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-0.37265315084205264	[492]	[209,203]	-3	hSpCas9	negative selection	1080259
47808242	47808265	6	-	26627737	GBM cells	viability after 21 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.049717198110367455	[104]	[57,59]	0	hSpCas9	negative selection	1080260
47808338	47808361	6	-	26627737	GBM cells	viability after 21 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	-0.24372999370475146	[484]	[209,233]	-2	hSpCas9	negative selection	1080261
47782086	47782109	6	-	26627737	RPE1	viability after 9 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.1293190973830981	[556]	[274,81]	0	hSpCas9	negative selection	1162571
47791842	47791865	6	-	26627737	RPE1	viability after 9 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.3502472157838239	[1563]	[466,826]	2	hSpCas9	negative selection	1162572
47795341	47795364	6	+	26627737	RPE1	viability after 9 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.5832645787279664	[640]	[287,316]	4	hSpCas9	negative selection	1162573
47795428	47795451	6	-	26627737	RPE1	viability after 9 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-0.13365668154197596	[2040]	[550,622]	-1	hSpCas9	negative selection	1162574
47808242	47808265	6	-	26627737	RPE1	viability after 9 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	2.8645214870101015	[77]	[193,156]	9	hSpCas9	negative selection	1162575
47808338	47808361	6	-	26627737	RPE1	viability after 9 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	1.028552033510274	[1384]	[839,941]	6	hSpCas9	negative selection	1162576
47782086	47782109	6	-	26627737	RPE1	viability after 12 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.01325558702970936	[556]	[219,77]	0	hSpCas9	negative selection	1244886
47791842	47791865	6	-	26627737	RPE1	viability after 12 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.2391167060715751	[1563]	[391,605]	1	hSpCas9	negative selection	1244887
47795341	47795364	6	+	26627737	RPE1	viability after 12 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.5529680217191286	[640]	[342,156]	3	hSpCas9	negative selection	1244888
47795428	47795451	6	-	26627737	RPE1	viability after 12 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-0.05525771836830384	[2040]	[535,518]	0	hSpCas9	negative selection	1244889
47808242	47808265	6	-	26627737	RPE1	viability after 12 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	2.24961050064285	[77]	[138,57]	9	hSpCas9	negative selection	1244890
47808338	47808361	6	-	26627737	RPE1	viability after 12 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	0.7971070979458754	[1384]	[563,733]	5	hSpCas9	negative selection	1244891
47782086	47782109	6	-	26627737	RPE1	viability after 15 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.8592442631252573	[556]	[94,78]	-5	hSpCas9	negative selection	1327201
47791842	47791865	6	-	26627737	RPE1	viability after 15 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.3082378741297114	[1563]	[361,726]	2	hSpCas9	negative selection	1327202
47795341	47795364	6	+	26627737	RPE1	viability after 15 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.536884404515729	[640]	[258,266]	3	hSpCas9	negative selection	1327203
47795428	47795451	6	-	26627737	RPE1	viability after 15 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-0.29352045942242233	[2040]	[410,528]	-2	hSpCas9	negative selection	1327204
47808242	47808265	6	-	26627737	RPE1	viability after 15 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	1.6464313189348894	[77]	[92,45]	8	hSpCas9	negative selection	1327205
47808338	47808361	6	-	26627737	RPE1	viability after 15 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	0.44114629456351473	[1384]	[451,608]	3	hSpCas9	negative selection	1327206
47782086	47782109	6	-	26627737	RPE1	viability after 18 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.18261026608844966	[556]	[159,102]	-1	hSpCas9	negative selection	1409516
47791842	47791865	6	-	26627737	RPE1	viability after 18 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.2123620823713448	[1563]	[328,659]	1	hSpCas9	negative selection	1409517
47795341	47795364	6	+	26627737	RPE1	viability after 18 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.8841215430960028	[640]	[297,341]	5	hSpCas9	negative selection	1409518
47795428	47795451	6	-	26627737	RPE1	viability after 18 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-0.319966856263862	[2040]	[491,386]	-2	hSpCas9	negative selection	1409519
47808242	47808265	6	-	26627737	RPE1	viability after 18 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	2.3352793671051706	[77]	[141,67]	9	hSpCas9	negative selection	1409520
47808338	47808361	6	-	26627737	RPE1	viability after 18 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	0.5581557619710307	[1384]	[559,539]	3	hSpCas9	negative selection	1409521
47782086	47782109	6	-	26627737	HeLa	viability after 8 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.13008867181215977	[425]	[276,279,76]	1	hSpCas9	negative selection	1491831
47791842	47791865	6	-	26627737	HeLa	viability after 8 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.4931266466273614	[679]	[816,258,271]	4	hSpCas9	negative selection	1491832
47795341	47795364	6	+	26627737	HeLa	viability after 8 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	-0.7059690999478208	[512]	[218,122,89]	-6	hSpCas9	negative selection	1491833
47795428	47795451	6	-	26627737	HeLa	viability after 8 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-1.6643152267501993	[1067]	[144,184,111]	-9	hSpCas9	negative selection	1491834
47808242	47808265	6	-	26627737	HeLa	viability after 8 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.9759478061861789	[150]	[137,186,68]	7	hSpCas9	negative selection	1491835
47808338	47808361	6	-	26627737	HeLa	viability after 8 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	1.2799116188493367	[423]	[558,517,301]	8	hSpCas9	negative selection	1491836
47782086	47782109	6	-	26627737	HeLa	viability after 12 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.15165576901736239	[425]	[164,306,101]	1	hSpCas9	negative selection	1574146
47791842	47791865	6	-	26627737	HeLa	viability after 12 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.23811290685120923	[679]	[358,108,263]	-2	hSpCas9	negative selection	1574147
47795341	47795364	6	+	26627737	HeLa	viability after 12 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	-0.7618527343583654	[512]	[55,238,65]	-6	hSpCas9	negative selection	1574148
47795428	47795451	6	-	26627737	HeLa	viability after 12 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-1.1755367528638692	[1067]	[151,175,258]	-8	hSpCas9	negative selection	1574149
47808242	47808265	6	-	26627737	HeLa	viability after 12 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.8458618636873179	[150]	[180,144,8]	6	hSpCas9	negative selection	1574150
47808338	47808361	6	-	26627737	HeLa	viability after 12 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	1.3465411990046574	[423]	[625,445,269]	8	hSpCas9	negative selection	1574151
47782086	47782109	6	-	26627737	HeLa	viability after 15 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.6536125183617811	[425]	[306,189,324]	5	hSpCas9	negative selection	1656461
47791842	47791865	6	-	26627737	HeLa	viability after 15 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.154837868208748	[679]	[317,118,312]	-1	hSpCas9	negative selection	1656462
47795341	47795364	6	+	26627737	HeLa	viability after 15 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	-0.019492671395610284	[512]	[208,191,217]	0	hSpCas9	negative selection	1656463
47795428	47795451	6	-	26627737	HeLa	viability after 15 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-1.272289523906915	[1067]	[201,93,248]	-8	hSpCas9	negative selection	1656464
47808242	47808265	6	-	26627737	HeLa	viability after 15 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	-0.29174740655983467	[150]	[68,11,70]	-3	hSpCas9	negative selection	1656465
47808338	47808361	6	-	26627737	HeLa	viability after 15 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	1.252516546388033	[423]	[510,448,260]	8	hSpCas9	negative selection	1656466
47782086	47782109	6	-	26627737	HeLa	viability after 18 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.6889347434095086	[425]	[212,164,324]	5	hSpCas9	negative selection	1738776
47791842	47791865	6	-	26627737	HeLa	viability after 18 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.15422882029353135	[679]	[213,97,312]	-1	hSpCas9	negative selection	1738777
47795341	47795364	6	+	26627737	HeLa	viability after 18 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	-0.005938760185065395	[512]	[139,163,217]	0	hSpCas9	negative selection	1738778
47795428	47795451	6	-	26627737	HeLa	viability after 18 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-1.3209089593241727	[1067]	[126,73,248]	-8	hSpCas9	negative selection	1738779
47808242	47808265	6	-	26627737	HeLa	viability after 18 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	-0.3496963804704567	[150]	[43,7,70]	-3	hSpCas9	negative selection	1738780
47808338	47808361	6	-	26627737	HeLa	viability after 18 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	1.2527126268112112	[423]	[341,372,260]	8	hSpCas9	negative selection	1738781
47782086	47782109	6	-	26627737	HCT116	viability after 6 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.8525353266318141	[558]	[38,53]	-5	hSpCas9	negative selection	1821091
47791842	47791865	6	-	26627737	HCT116	viability after 6 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.053512776685005536	[982]	[180,148]	0	hSpCas9	negative selection	1821092
47795341	47795364	6	+	26627737	HCT116	viability after 6 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.6967829955614745	[687]	[436,30]	4	hSpCas9	negative selection	1821093
47795428	47795451	6	-	26627737	HCT116	viability after 6 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	1.2358940315574625	[784]	[610,113]	6	hSpCas9	negative selection	1821094
47808242	47808265	6	-	26627737	HCT116	viability after 6 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	-0.2802551404838358	[244]	[3,46]	-1	hSpCas9	negative selection	1821095
47808338	47808361	6	-	26627737	HCT116	viability after 6 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	0.5737771226081125	[865]	[259,170]	3	hSpCas9	negative selection	1821096
47782086	47782109	6	-	26627737	HCT116	viability after 8 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.2924211901730055	[177]	[177,112,70]	3	hSpCas9	negative selection	1903406
47791842	47791865	6	-	26627737	HCT116	viability after 8 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.030347935423259864	[534]	[224,280,357]	0	hSpCas9	negative selection	1903407
47795341	47795364	6	+	26627737	HCT116	viability after 8 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.4534259951915374	[287]	[198,352,100]	5	hSpCas9	negative selection	1903408
47795428	47795451	6	-	26627737	HCT116	viability after 8 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-0.27663932318310147	[712]	[349,344,278]	-3	hSpCas9	negative selection	1903409
47808242	47808265	6	-	26627737	HCT116	viability after 8 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.7601005479933604	[121]	[128,112,99]	7	hSpCas9	negative selection	1903410
47808338	47808361	6	-	26627737	HCT116	viability after 8 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	-0.2305859215181787	[617]	[210,426,231]	-3	hSpCas9	negative selection	1903411
47782086	47782109	6	-	26627737	HCT116	viability after 9 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.3988189136344365	[558]	[131,247]	3	hSpCas9	negative selection	1985721
47791842	47791865	6	-	26627737	HCT116	viability after 9 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.19518501160628132	[982]	[371,243]	1	hSpCas9	negative selection	1985722
47795341	47795364	6	+	26627737	HCT116	viability after 9 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.34958958397955897	[687]	[156,294]	2	hSpCas9	negative selection	1985723
47795428	47795451	6	-	26627737	HCT116	viability after 9 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	1.2733853792165974	[784]	[399,590]	8	hSpCas9	negative selection	1985724
47808242	47808265	6	-	26627737	HCT116	viability after 9 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.20097806156582454	[244]	[120,38]	1	hSpCas9	negative selection	1985725
47808338	47808361	6	-	26627737	HCT116	viability after 9 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	0.9191480502295102	[865]	[386,476]	6	hSpCas9	negative selection	1985726
47782086	47782109	6	-	26627737	HCT116	viability after 12 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.6270816726442493	[177]	[100,175,160]	6	hSpCas9	negative selection	2068036
47791842	47791865	6	-	26627737	HCT116	viability after 12 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.14285570078505194	[534]	[283,244,402]	1	hSpCas9	negative selection	2068037
47795341	47795364	6	+	26627737	HCT116	viability after 12 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.8745340549035177	[287]	[219,420,199]	7	hSpCas9	negative selection	2068038
47795428	47795451	6	-	26627737	HCT116	viability after 12 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-0.13712812383349138	[712]	[249,375,404]	-1	hSpCas9	negative selection	2068039
47808242	47808265	6	-	26627737	HCT116	viability after 12 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.11123000246853798	[121]	[19,106,85]	1	hSpCas9	negative selection	2068040
47808338	47808361	6	-	26627737	HCT116	viability after 12 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	-0.23276793533758333	[617]	[263,348,218]	-2	hSpCas9	negative selection	2068041
47782086	47782109	6	-	26627737	HCT116	viability after 15 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	1.2932770995783485	[177]	[203,378,163]	8	hSpCas9	negative selection	2150351
47791842	47791865	6	-	26627737	HCT116	viability after 15 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.03162165329913336	[534]	[425,315,214]	0	hSpCas9	negative selection	2150352
47795341	47795364	6	+	26627737	HCT116	viability after 15 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.6908309232829972	[287]	[343,337,129]	6	hSpCas9	negative selection	2150353
47795428	47795451	6	-	26627737	HCT116	viability after 15 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-0.22732947773891254	[712]	[404,213,435]	-2	hSpCas9	negative selection	2150354
47808242	47808265	6	-	26627737	HCT116	viability after 15 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.7138409532440718	[121]	[76,136,125]	6	hSpCas9	negative selection	2150355
47808338	47808361	6	-	26627737	HCT116	viability after 15 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	-0.07236147700458406	[617]	[325,492,193]	0	hSpCas9	negative selection	2150356
47782086	47782109	6	-	26627737	HCT116	viability after 18 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.4255297232294764	[177]	[102,126,115]	3	hSpCas9	negative selection	2232666
47791842	47791865	6	-	26627737	HCT116	viability after 18 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.5471035253720382	[534]	[207,693,202]	4	hSpCas9	negative selection	2232667
47795341	47795364	6	+	26627737	HCT116	viability after 18 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.40892714890614895	[287]	[175,261,107]	3	hSpCas9	negative selection	2232668
47795428	47795451	6	-	26627737	HCT116	viability after 18 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	-0.527718994897752	[712]	[246,169,307]	-5	hSpCas9	negative selection	2232669
47808242	47808265	6	-	26627737	HCT116	viability after 18 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.24650276074715083	[121]	[3,121,80]	2	hSpCas9	negative selection	2232670
47808338	47808361	6	-	26627737	HCT116	viability after 18 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	0.18377708283619598	[617]	[420,357,232]	1	hSpCas9	negative selection	2232671
47791869	47791892	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.06723525997413515	[5,5]	[6,4]	1	hSpCas9	positive selection	3007444
47791842	47791865	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.23733824084566135	[2,3]	[2,2]	5	hSpCas9	positive selection	3007445
47795280	47795303	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	-0.41286849259578795	[3,3]	[2,1]	-5	hSpCas9	positive selection	3007446
47795306	47795329	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TAGTCCCCCAGACCTACCAAGGG	OPN5	ENSG00000124818	-0.5967344874669044	[3,3]	[3,0]	-7	hSpCas9	positive selection	3007447
47791869	47791892	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.13303621490232875	[5,5]	[5,3]	2	hSpCas9	positive selection	3075302
47791842	47791865	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.6420127360326516	[2,2]	[3,2]	9	hSpCas9	positive selection	3075303
47795280	47795303	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.5443942462291805	[3,3]	[3,3]	8	hSpCas9	positive selection	3075304
47795306	47795329	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TAGTCCCCCAGACCTACCAAGGG	OPN5	ENSG00000124818	-0.07611907937953259	[3,3]	[2,2]	-1	hSpCas9	positive selection	3075305
47782143	47782166		-	24336571	A375	resistance to PLX after 7 days	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.057380711706337406	[20,15]	[20,17]	2	hSpCas9	positive selection	3132495
47782117	47782140		-	24336571	A375	resistance to PLX after 7 days	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	-0.5133064943610162	[4,4]	[2,2]	-9	hSpCas9	positive selection	3132496
47786603	47786626		+	24336571	A375	resistance to PLX after 7 days	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.08624272962959056	[18,20]	[21,19]	3	hSpCas9	positive selection	3132497
47782143	47782166		-	24336571	A375	resistance to PLX after 14 days	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	1.2447255622821585	[17,12]	[15,16]	8	hSpCas9	positive selection	3190288
47782117	47782140		-	24336571	A375	resistance to PLX after 14 days	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.32084317878453317	[4,2]	[1,1]	3	hSpCas9	positive selection	3190289
47786603	47786626		+	24336571	A375	resistance to PLX after 14 days	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.9460671873402462	[22,21]	[19,20]	7	hSpCas9	positive selection	3190290
47782143	47782166		-	24336571	A375	viability after 7 days	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.49640154812071446	[13]	[20,15]	7	hSpCas9	negative selection	3248081
47782117	47782140		-	24336571	A375	viability after 7 days	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	-0.47280130005803656	[7]	[4,4]	-6	hSpCas9	negative selection	3248082
47786603	47786626		+	24336571	A375	viability after 7 days	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.6046299771819212	[13]	[18,20]	8	hSpCas9	negative selection	3248083
47782143	47782166		-	24336571	A375	viability after 14 days	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.20830355328721745	[13]	[17,12]	2	hSpCas9	negative selection	3305874
47782117	47782140		-	24336571	A375	viability after 14 days	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	-0.813109783085091	[7]	[4,2]	-7	hSpCas9	negative selection	3305875
47786603	47786626		+	24336571	A375	viability after 14 days	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.8044261715013153	[13]	[22,21]	8	hSpCas9	negative selection	3305876
47786603	47786626	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	-0.17730201619088934	[172,172]	[0,0]	-1	hSpCas9	positive selection	3383056
47782143	47782166	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.6134700216711103	[99,99]	[0,0]	3	hSpCas9	positive selection	3383057
47786546	47786569	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	-1.7113405817493734	[500,500]	[0,0]	-9	hSpCas9	positive selection	3383058
47791869	47791892	6	-	26780180	HT29	viability (Avana library 4 designs)	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.029348271299611	[]	[]	0	hSpCas9	negative selection	3445378
47791842	47791865	6	-	26780180	HT29	viability (Avana library 4 designs)	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	3.960745190059	[]	[]	9	hSpCas9	negative selection	3445379
47795280	47795303	6	-	26780180	HT29	viability (Avana library 4 designs)	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	1.66198034069821	[]	[]	6	hSpCas9	negative selection	3445380
47795306	47795329	6	-	26780180	HT29	viability (Avana library 4 designs)	TAGTCCCCCAGACCTACCAAGGG	OPN5	ENSG00000124818	0.995217220860494	[]	[]	4	hSpCas9	negative selection	3445381
47791842	47791865	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.353388183344574	[]	[]	0	hSpCas9	negative selection	3538079
47795306	47795329	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	TAGTCCCCCAGACCTACCAAGGG	OPN5	ENSG00000124818	1.2324367036778	[]	[]	1	hSpCas9	negative selection	3538080
47795280	47795303	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	6.80956539517069	[]	[]	9	hSpCas9	negative selection	3538081
47791869	47791892	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	1.3356294605114	[]	[]	2	hSpCas9	negative selection	3538082
47782086	47782109	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	3.6403794616806	[]	[]	6	hSpCas9	negative selection	3538083
47795271	47795294	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAAGGAAGCATAGGCCCAGATGG	OPN5	ENSG00000124818	5.33760340369356	[]	[]	8	hSpCas9	negative selection	3538084
47791842	47791865	6	-	26780180	A375	viability (Avana lentiGuide)	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-5.63076290577194	[]	[]	-8	hSpCas9	negative selection	3646738
47795306	47795329	6	-	26780180	A375	viability (Avana lentiGuide)	TAGTCCCCCAGACCTACCAAGGG	OPN5	ENSG00000124818	15.3219431947615	[]	[]	8	hSpCas9	negative selection	3646739
47795280	47795303	6	-	26780180	A375	viability (Avana lentiGuide)	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	-7.17427362025729	[]	[]	-9	hSpCas9	negative selection	3646740
47791869	47791892	6	-	26780180	A375	viability (Avana lentiGuide)	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	-2.51898105818966	[]	[]	-4	hSpCas9	negative selection	3646741
47782086	47782109	6	-	26780180	A375	viability (Avana lentiGuide)	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	2.4917795664434	[]	[]	2	hSpCas9	negative selection	3646742
47795271	47795294	6	-	26780180	A375	viability (Avana lentiGuide)	GAAGGAAGCATAGGCCCAGATGG	OPN5	ENSG00000124818	-0.914191784054403	[]	[]	-1	hSpCas9	negative selection	3646743
47791842	47791865	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.05818803210149025	[4]	[5,3]	-1	hSpCas9	positive selection	3755397
47795306	47795329	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAGTCCCCCAGACCTACCAAGGG	OPN5	ENSG00000124818	0.021062312589246818	[5]	[5,4]	0	hSpCas9	positive selection	3755398
47795280	47795303	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.3220854308151421	[3]	[4,4]	8	hSpCas9	positive selection	3755399
47791869	47791892	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.07186532710704296	[6]	[7,6]	1	hSpCas9	positive selection	3755400
47782086	47782109	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.3527977389810367	[3]	[4,5]	9	hSpCas9	positive selection	3755401
47795271	47795294	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAGGAAGCATAGGCCCAGATGG	OPN5	ENSG00000124818	0.24316121476453917	[4]	[5,5]	7	hSpCas9	positive selection	3755402
47791842	47791865	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.3048111580648414	[4]	[4,5]	8	hSpCas9	positive selection	3864004
47795306	47795329	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAGTCCCCCAGACCTACCAAGGG	OPN5	ENSG00000124818	-0.20991802618442687	[5]	[5,1]	-3	hSpCas9	positive selection	3864005
47795280	47795303	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.29992473797638197	[4]	[4,5]	8	hSpCas9	positive selection	3864006
47791869	47791892	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.25512931968136876	[7]	[7,7]	6	hSpCas9	positive selection	3864007
47782086	47782109	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.06510721460826657	[4]	[2,5]	-1	hSpCas9	positive selection	3864008
47795271	47795294	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAGGAAGCATAGGCCCAGATGG	OPN5	ENSG00000124818	-0.15038730788565824	[5]	[5,2]	-2	hSpCas9	positive selection	3864009
47782143	47782166	6	-	26780180	A375	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	1.0218426682661	[]	[]	5	hSpCas9	negative selection	3975144
47782117	47782140	6	-	26780180	A375	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.86237834187253	[]	[]	3	hSpCas9	negative selection	3975145
47786603	47786626	6	+	26780180	A375	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.443859104392186	[]	[]	1	hSpCas9	negative selection	3975146
47791842	47791865	6	-	26780180	A375	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.312847914323523	[]	[]	0	hSpCas9	negative selection	3975147
47786546	47786569	6	-	26780180	A375	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.14542361533917	[]	[]	0	hSpCas9	negative selection	3975148
47791853	47791876	6	+	26780180	A375	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.731845708940695	[]	[]	2	hSpCas9	negative selection	3975149
47782143	47782166	6	-	26780180	HT29	viability (GeCKOv2 library)	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	1.02391454567066	[]	[]	4	hSpCas9	negative selection	4083110
47782117	47782140	6	-	26780180	HT29	viability (GeCKOv2 library)	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.831458927769718	[]	[]	3	hSpCas9	negative selection	4083111
47786603	47786626	6	+	26780180	HT29	viability (GeCKOv2 library)	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.139169366028322	[]	[]	0	hSpCas9	negative selection	4083112
47791842	47791865	6	-	26780180	HT29	viability (GeCKOv2 library)	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.822110669290985	[]	[]	3	hSpCas9	negative selection	4083113
47786546	47786569	6	-	26780180	HT29	viability (GeCKOv2 library)	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.79733258902331	[]	[]	3	hSpCas9	negative selection	4083114
47791853	47791876	6	+	26780180	HT29	viability (GeCKOv2 library)	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.831747146983088	[]	[]	3	hSpCas9	negative selection	4083115
47782143	47782166	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.5078902463573823	[4]	[4,4]	9	hSpCas9	positive selection	4157288
47782117	47782140	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	-0.44524071177445323	[2]	[0,0]	-8	hSpCas9	positive selection	4157289
47786603	47786626	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.4305655139246334	[4]	[3,4]	8	hSpCas9	positive selection	4157290
47782143	47782166	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	1.2162946234322067	[3]	[2,0,5,3]	8	hSpCas9	positive selection	4221310
47782117	47782140	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.37169404666393724	[1]	[2,0,0,0]	3	hSpCas9	positive selection	4221311
47786603	47786626	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	1.2319702939144972	[3]	[4,3,4,3]	8	hSpCas9	positive selection	4221312
47791853	47791876	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.11851767790214968	[2]	[2,1]	2	hSpCas9	positive selection	4287093
47782117	47782140	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	-0.025894138772378977	[2]	[2,0]	0	hSpCas9	positive selection	4287094
47791842	47791865	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.17212895119204483	[3]	[3,2]	3	hSpCas9	positive selection	4287095
47786603	47786626	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.24782273555647327	[2]	[3,1]	5	hSpCas9	positive selection	4351348
47782143	47782166	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.009528628062033306	[2]	[3,0]	0	hSpCas9	positive selection	4351349
47786546	47786569	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.5159803159035579	[4]	[4,4]	9	hSpCas9	positive selection	4351350
47786583	47786605	6	-	27760321	OCIAML3	viability	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	-0.2514059088452376	[151,154]	[102,98]	-3	hSpCas9	negative selection	4424665
47791828	47791850	6	+	27760321	OCIAML3	viability	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	0.9432439088370823	[913,873]	[1361,1325]	9	hSpCas9	negative selection	4424666
47791935	47791957	6	-	27760321	OCIAML3	viability	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	0.6067149801327345	[262,256]	[269,362]	7	hSpCas9	negative selection	4424667
47795225	47795247	6	-	27760321	OCIAML3	viability	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	0.5801307399423767	[382,349]	[311,579]	7	hSpCas9	negative selection	4424668
47795298	47795320	6	-	27760321	OCIAML3	viability	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	1.1423116443693495	[472,362]	[611,851]	9	hSpCas9	negative selection	4424669
47786583	47786605	6	-	27760321	OCIAML2	viability	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	0.2684901695430464	[151,154]	[122,185]	3	hSpCas9	negative selection	4508128
47791828	47791850	6	+	27760321	OCIAML2	viability	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	0.7546554241792436	[913,873]	[1035,1466]	8	hSpCas9	negative selection	4508129
47791935	47791957	6	-	27760321	OCIAML2	viability	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	0.0868327736481328	[262,256]	[175,286]	1	hSpCas9	negative selection	4508130
47795225	47795247	6	-	27760321	OCIAML2	viability	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	0.948922561646805	[382,349]	[493,674]	9	hSpCas9	negative selection	4508131
47795298	47795320	6	-	27760321	OCIAML2	viability	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.4421003901649677	[472,362]	[442,472]	6	hSpCas9	negative selection	4508132
47786583	47786605	6	-	27760321	MV411	viability	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	0.6152612811209383	[151,154]	[156,153]	4	hSpCas9	negative selection	4591591
47791828	47791850	6	+	27760321	MV411	viability	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	1.5319057986338418	[913,873]	[1488,2037]	9	hSpCas9	negative selection	4591592
47791935	47791957	6	-	27760321	MV411	viability	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	1.181384050165568	[262,256]	[425,335]	8	hSpCas9	negative selection	4591593
47795225	47795247	6	-	27760321	MV411	viability	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	0.5362183889271241	[382,349]	[330,379]	4	hSpCas9	negative selection	4591594
47795298	47795320	6	-	27760321	MV411	viability	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.12863826235832554	[472,362]	[174,485]	0	hSpCas9	negative selection	4591595
47786583	47786605	6	-	27760321	HL60	viability	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	-1.2251997993763453	[151,154]	[48,58]	-8	hSpCas9	negative selection	4675054
47791828	47791850	6	+	27760321	HL60	viability	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	0.8484787933488938	[913,873]	[1245,1391]	8	hSpCas9	negative selection	4675055
47791935	47791957	6	-	27760321	HL60	viability	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	0.8669968917474249	[262,256]	[330,448]	8	hSpCas9	negative selection	4675056
47795225	47795247	6	-	27760321	HL60	viability	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	0.13423438752369224	[382,349]	[309,347]	1	hSpCas9	negative selection	4675057
47795298	47795320	6	-	27760321	HL60	viability	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.24216086863776767	[472,362]	[394,406]	3	hSpCas9	negative selection	4675058
47786583	47786605	6	-	27760321	HT1080	viability	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	-1.537836256953701	[154,120]	[6,31]	-5	hSpCas9	negative selection	4758517
47791828	47791850	6	+	27760321	HT1080	viability	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	1.5435461539803914	[873,681]	[923,880]	8	hSpCas9	negative selection	4758518
47791935	47791957	6	-	27760321	HT1080	viability	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	0.260846994706738	[256,200]	[94,124]	1	hSpCas9	negative selection	4758519
47795225	47795247	6	-	27760321	HT1080	viability	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	0.4180940752200837	[349,272]	[266,54]	2	hSpCas9	negative selection	4758520
47795298	47795320	6	-	27760321	HT1080	viability	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	1.8526591925988838	[362,282]	[531,390]	8	hSpCas9	negative selection	4758521
47786583	47786605	6	-	27760321	HT29	viability after 7 days	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	-1.0583635156761142	[154,120]	[41,143,63]	-8	hSpCas9	negative selection	4841980
47791828	47791850	6	+	27760321	HT29	viability after 7 days	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	-0.007344421527451628	[873,681]	[1273,789,960]	0	hSpCas9	negative selection	4841981
47791935	47791957	6	-	27760321	HT29	viability after 7 days	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	0.2357269942111846	[256,200]	[397,301,346]	3	hSpCas9	negative selection	4841982
47795225	47795247	6	-	27760321	HT29	viability after 7 days	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	-0.005565091305616471	[349,272]	[625,310,294]	0	hSpCas9	negative selection	4841983
47795298	47795320	6	-	27760321	HT29	viability after 7 days	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.22781217708920165	[362,282]	[423,529,494]	3	hSpCas9	negative selection	4841984
47786583	47786605	6	-	27760321	HT29	viability after 25 days	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	-1.5692088290529842	[154,120]	[110,14,26]	-7	hSpCas9	negative selection	4925443
47791828	47791850	6	+	27760321	HT29	viability after 25 days	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	0.5380040453389583	[873,681]	[1548,1114,1178]	6	hSpCas9	negative selection	4925444
47791935	47791957	6	-	27760321	HT29	viability after 25 days	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	-1.1610646819316404	[256,200]	[72,57,234]	-7	hSpCas9	negative selection	4925445
47795225	47795247	6	-	27760321	HT29	viability after 25 days	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	0.3784925693821092	[349,272]	[441,353,607]	4	hSpCas9	negative selection	4925446
47795298	47795320	6	-	27760321	HT29	viability after 25 days	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.8595918697670352	[362,282]	[657,706,640]	8	hSpCas9	negative selection	4925447
47786583	47786605	6	-	27760321	HT29	viability after 22 days	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	-1.508639696568145	[154,120]	[126,12,25]	-7	hSpCas9	negative selection	5008906
47791828	47791850	6	+	27760321	HT29	viability after 22 days	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	0.6390463243997533	[873,681]	[1225,1532,1447]	7	hSpCas9	negative selection	5008907
47791935	47791957	6	-	27760321	HT29	viability after 22 days	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	-0.4235296874879435	[256,200]	[127,174,291]	-4	hSpCas9	negative selection	5008908
47795225	47795247	6	-	27760321	HT29	viability after 22 days	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	-0.22548211467718995	[349,272]	[296,346,279]	-2	hSpCas9	negative selection	5008909
47795298	47795320	6	-	27760321	HT29	viability after 22 days	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.8650923463608385	[362,282]	[583,971,484]	8	hSpCas9	negative selection	5008910
47786583	47786605	6	-	27760321	HT29	viability after 19 days	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	-1.6179349449748783	[154,120]	[88,66,3]	-7	hSpCas9	negative selection	5092369
47791828	47791850	6	+	27760321	HT29	viability after 19 days	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	0.231713321544728	[873,681]	[1189,863,1092]	2	hSpCas9	negative selection	5092370
47791935	47791957	6	-	27760321	HT29	viability after 19 days	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	-0.40692759766037767	[256,200]	[243,144,207]	-4	hSpCas9	negative selection	5092371
47795225	47795247	6	-	27760321	HT29	viability after 19 days	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	0.0924981621750178	[349,272]	[380,502,259]	0	hSpCas9	negative selection	5092372
47795298	47795320	6	-	27760321	HT29	viability after 19 days	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.7383676363232851	[362,282]	[843,595,438]	7	hSpCas9	negative selection	5092373
47786583	47786605	6	-	27760321	HT29	viability after 16 days	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	-1.6777881786026274	[154,120]	[116,19,14]	-8	hSpCas9	negative selection	5175832
47791828	47791850	6	+	27760321	HT29	viability after 16 days	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	0.29514437210549627	[873,681]	[1170,1243,793]	3	hSpCas9	negative selection	5175833
47791935	47791957	6	-	27760321	HT29	viability after 16 days	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	-0.7151863521642474	[256,200]	[288,70,122]	-6	hSpCas9	negative selection	5175834
47795225	47795247	6	-	27760321	HT29	viability after 16 days	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	-0.23263865324946395	[349,272]	[411,167,323]	-3	hSpCas9	negative selection	5175835
47795298	47795320	6	-	27760321	HT29	viability after 16 days	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.5774968336803692	[362,282]	[898,369,386]	6	hSpCas9	negative selection	5175836
47786583	47786605	6	-	27760321	HT29	viability after 13 days	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	-0.44987650006847657	[154,120]	[161,131,60]	-5	hSpCas9	negative selection	5259295
47791828	47791850	6	+	27760321	HT29	viability after 13 days	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	0.28142934058890345	[873,681]	[945,1417,936]	3	hSpCas9	negative selection	5259296
47791935	47791957	6	-	27760321	HT29	viability after 13 days	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	-0.9262651176418131	[256,200]	[125,179,114]	-7	hSpCas9	negative selection	5259297
47795225	47795247	6	-	27760321	HT29	viability after 13 days	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	0.16876341041743873	[349,272]	[657,239,324]	2	hSpCas9	negative selection	5259298
47795298	47795320	6	-	27760321	HT29	viability after 13 days	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	-0.044106637854902486	[362,282]	[334,353,398]	0	hSpCas9	negative selection	5259299
47786583	47786605	6	-	27760321	HT29	viability after 10 days	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	-0.7128663695337272	[154,120]	[51,201,64]	-7	hSpCas9	negative selection	5342758
47791828	47791850	6	+	27760321	HT29	viability after 10 days	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	-0.0797843256775177	[873,681]	[1004,676,1064]	-1	hSpCas9	negative selection	5342759
47791935	47791957	6	-	27760321	HT29	viability after 10 days	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	-1.4886564857705538	[256,200]	[133,113,58]	-8	hSpCas9	negative selection	5342760
47795225	47795247	6	-	27760321	HT29	viability after 10 days	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	0.04128576472498463	[349,272]	[414,462,325]	0	hSpCas9	negative selection	5342761
47795298	47795320	6	-	27760321	HT29	viability after 10 days	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.5028683257453949	[362,282]	[541,600,571]	7	hSpCas9	negative selection	5342762
47786583	47786605	6	-	27760321	MOLM13	viability	TGATAGTCATTATTTCAGCGGG	OPN5	ENSG00000124818	-0.6789568368786367	[151,154]	[2,97]	-4	hSpCas9	negative selection	5426221
47791828	47791850	6	+	27760321	MOLM13	viability	TCTTGCTTTTGTCACCGCTGGG	OPN5	ENSG00000124818	1.5846022674113893	[913,873]	[2180,947]	9	hSpCas9	negative selection	5426222
47791935	47791957	6	-	27760321	MOLM13	viability	GATTTTCAAATATCGATCCAGG	OPN5	ENSG00000124818	-0.7254713046020803	[262,256]	[136,47]	-4	hSpCas9	negative selection	5426223
47795225	47795247	6	-	27760321	MOLM13	viability	TTCTTTTCAGCCAAACCCCTGG	OPN5	ENSG00000124818	0.9493331414311535	[382,349]	[336,451]	6	hSpCas9	negative selection	5426224
47795298	47795320	6	-	27760321	MOLM13	viability	AGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	2.817933421003162	[472,362]	[2988,510]	9	hSpCas9	negative selection	5426225
47787065	47787088	6	+	27661255	K562	viability	GACAGTTGAAGGCAGTTGAGAGG	OPN5	ENSG00000124818	0.17712939864771038	[1007,1237]	[1003,1015]	6	dCas9-KRAB	negative selection	5498473
47787505	47787528	6	+	27661255	K562	viability	GGTTTTAGGTCATTAGAGTAGGG	OPN5	ENSG00000124818	0.07732839880611264	[2558,3132]	[2621,2191]	2	dCas9-KRAB	negative selection	5498474
47787113	47787136	6	-	27661255	K562	viability	GATTACATATATCATCAGCAGGG	OPN5	ENSG00000124818	-0.028526406971998375	[1417,1455]	[1261,1007]	-1	dCas9-KRAB	negative selection	5498475
47791853	47791876	6	+	27260156	BXPC3	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.16229233854392688	[212]	[266,220,199,313]	3	hSpCas9	negative selection	5559553
47782117	47782140	6	-	27260156	BXPC3	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.27299212369082015	[287]	[227,426,408,405]	6	hSpCas9	negative selection	5559554
47791842	47791865	6	-	27260156	BXPC3	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.3007000244759287	[555]	[760,716,741,622]	6	hSpCas9	negative selection	5559555
47786603	47786626	6	+	27260156	BXPC3	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	-0.026906787089938156	[345]	[245,300,461,435]	0	hSpCas9	negative selection	5623808
47782143	47782166	6	-	27260156	BXPC3	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.2026113849939939	[289]	[182,383,221,263]	-5	hSpCas9	negative selection	5623809
47786546	47786569	6	-	27260156	BXPC3	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.11510957112159459	[1176]	[1070,1299,1294,1735]	2	hSpCas9	negative selection	5623810
47791853	47791876	6	+	27260156	A673	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.22966931808844804	[212]	[362,271,260,311]	5	hSpCas9	negative selection	5680804
47782117	47782140	6	-	27260156	A673	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.2656747667830721	[287]	[540,441,352,335]	6	hSpCas9	negative selection	5680805
47791842	47791865	6	-	27260156	A673	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.10507664571060871	[555]	[884,618,612,779]	2	hSpCas9	negative selection	5680806
47786603	47786626	6	+	27260156	A673	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.17157427501207279	[345]	[437,345,472,621]	4	hSpCas9	negative selection	5745059
47782143	47782166	6	-	27260156	A673	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.2527352612179319	[289]	[331,244,306,289]	-6	hSpCas9	negative selection	5745060
47786546	47786569	6	-	27260156	A673	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.02766296264887047	[1176]	[1684,1334,1338,1431]	0	hSpCas9	negative selection	5745061
47791853	47791876	6	+	27260156	A375	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.4663988988479413	[212]	[251,453,363,320]	6	hSpCas9	negative selection	5802055
47782117	47782140	6	-	27260156	A375	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.27581503514424455	[287]	[209,636,422,389]	4	hSpCas9	negative selection	5802056
47791842	47791865	6	-	27260156	A375	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.584217280363182	[555]	[1099,1028,886,892]	8	hSpCas9	negative selection	5802057
47786603	47786626	6	+	27260156	A375	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.4713452362662891	[345]	[610,522,584,519]	7	hSpCas9	negative selection	5866310
47782143	47782166	6	-	27260156	A375	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.0625083511814617	[289]	[504,365,308,248]	0	hSpCas9	negative selection	5866311
47786546	47786569	6	-	27260156	A375	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.27609152917843227	[1176]	[1695,1900,1873,1262]	4	hSpCas9	negative selection	5866312
47791853	47791876	6	+	27260156	COLO741	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.29449016297059294	[212]	[170,295,195]	-6	hSpCas9	negative selection	5923306
47782117	47782140	6	-	27260156	COLO741	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.3852306384391045	[287]	[404,360,654]	7	hSpCas9	negative selection	5923307
47791842	47791865	6	-	27260156	COLO741	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.2888390177027196	[555]	[864,987,756]	6	hSpCas9	negative selection	5923308
47786603	47786626	6	+	27260156	COLO741	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.44386618046973025	[345]	[625,622,558]	8	hSpCas9	negative selection	5987561
47782143	47782166	6	-	27260156	COLO741	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.022309874013834108	[289]	[544,203,359]	0	hSpCas9	negative selection	5987562
47786546	47786569	6	-	27260156	COLO741	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.08130187505882969	[1176]	[1589,1762,1428]	1	hSpCas9	negative selection	5987563
47791853	47791876	6	+	27260156	CAL120	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.14484277811115187	[212]	[412,354,131]	2	hSpCas9	negative selection	6044557
47782117	47782140	6	-	27260156	CAL120	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.05914464846981293	[287]	[489,411,237]	0	hSpCas9	negative selection	6044558
47791842	47791865	6	-	27260156	CAL120	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.0944751673002926	[555]	[687,603,912]	1	hSpCas9	negative selection	6044559
47786603	47786626	6	+	27260156	CAL120	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.004551705665638561	[345]	[699,208,426]	0	hSpCas9	negative selection	6108812
47782143	47782166	6	-	27260156	CAL120	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.023258435738556238	[289]	[395,259,446]	0	hSpCas9	negative selection	6108813
47786546	47786569	6	-	27260156	CAL120	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.3956429179035337	[1176]	[1582,1780,2355]	6	hSpCas9	negative selection	6108814
47791853	47791876	6	+	27260156	CADOES1	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.1456267523704875	[212]	[162,317,174,220]	2	hSpCas9	negative selection	6165808
47782117	47782140	6	-	27260156	CADOES1	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.2872477077740027	[287]	[347,376,192,391]	5	hSpCas9	negative selection	6165809
47791842	47791865	6	-	27260156	CADOES1	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.12332891184159667	[555]	[559,523,451,722]	2	hSpCas9	negative selection	6165810
47786603	47786626	6	+	27260156	CADOES1	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.35918288221731914	[345]	[423,297,459,470]	6	hSpCas9	negative selection	6230063
47782143	47782166	6	-	27260156	CADOES1	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.22333104396816156	[289]	[248,400,392,212]	4	hSpCas9	negative selection	6230064
47786546	47786569	6	-	27260156	CADOES1	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.2917631154861817	[1176]	[1365,1387,1219,1387]	5	hSpCas9	negative selection	6230065
47791853	47791876	6	+	27260156	EWS502	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.02031658516296142	[212]	[252,197,197,237]	0	hSpCas9	negative selection	6287059
47782117	47782140	6	-	27260156	EWS502	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.32672687051893157	[287]	[386,480,331,318]	6	hSpCas9	negative selection	6287060
47791842	47791865	6	-	27260156	EWS502	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.20433561304224263	[555]	[400,749,842,755]	3	hSpCas9	negative selection	6287061
47786603	47786626	6	+	27260156	EWS502	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.45433138794337086	[345]	[494,579,428,498]	7	hSpCas9	negative selection	6351314
47782143	47782166	6	-	27260156	EWS502	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.33152889358185744	[289]	[185,180,309,313]	-5	hSpCas9	negative selection	6351315
47786546	47786569	6	-	27260156	EWS502	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.19544206859883229	[1176]	[1445,1577,1346,1315]	3	hSpCas9	negative selection	6351316
47791853	47791876	6	+	27260156	EW8	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.10762876111942132	[212]	[170,165,181,118]	-2	hSpCas9	negative selection	6408310
47782117	47782140	6	-	27260156	EW8	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.46957471712035403	[287]	[404,269,230,409]	8	hSpCas9	negative selection	6408311
47791842	47791865	6	-	27260156	EW8	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.23578114978343595	[555]	[587,479,445,626]	4	hSpCas9	negative selection	6408312
47786603	47786626	6	+	27260156	EW8	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.15458502191882345	[345]	[330,284,296,338]	3	hSpCas9	negative selection	6472565
47782143	47782166	6	-	27260156	EW8	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.0006616542398010239	[289]	[210,331,204,193]	0	hSpCas9	negative selection	6472566
47786546	47786569	6	-	27260156	EW8	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.28864538872601964	[1176]	[1529,1056,1053,1074]	5	hSpCas9	negative selection	6472567
47791853	47791876	6	+	27260156	CORL105	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.21248298799854803	[212]	[320,210,344,289]	4	hSpCas9	negative selection	6529561
47782117	47782140	6	-	27260156	CORL105	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.23005543498727266	[287]	[472,409,317,370]	4	hSpCas9	negative selection	6529562
47791842	47791865	6	-	27260156	CORL105	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.17298146530663255	[555]	[781,730,746,678]	3	hSpCas9	negative selection	6529563
47786603	47786626	6	+	27260156	CORL105	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.46102793215926474	[345]	[559,639,526,496]	8	hSpCas9	negative selection	6593816
47782143	47782166	6	-	27260156	CORL105	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.05441972151666008	[289]	[225,412,461,222]	-1	hSpCas9	negative selection	6593817
47786546	47786569	6	-	27260156	CORL105	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	-0.01312166598226927	[1176]	[1341,1259,1565,1325]	0	hSpCas9	negative selection	6593818
47791853	47791876	6	+	27260156	HS294T	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.7867959082824366	[212]	[210,77,163,103]	8	hSpCas9	negative selection	6650812
47782117	47782140	6	-	27260156	HS294T	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	-0.05278726546706958	[287]	[72,102,111,151]	0	hSpCas9	negative selection	6650813
47791842	47791865	6	-	27260156	HS294T	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.07999049365101718	[555]	[120,173,257,281]	-1	hSpCas9	negative selection	6650814
47786603	47786626	6	+	27260156	HS294T	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.11115372928189604	[345]	[161,135,128,149]	1	hSpCas9	negative selection	6715067
47782143	47782166	6	-	27260156	HS294T	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.09574721544243336	[289]	[135,148,117,63]	1	hSpCas9	negative selection	6715068
47786546	47786569	6	-	27260156	HS294T	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	-0.11318799527306167	[1176]	[258,528,417,500]	-1	hSpCas9	negative selection	6715069
47791853	47791876	6	+	27260156	HCC44	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.21739001503473943	[212]	[257,182,227,170]	-4	hSpCas9	negative selection	6772063
47782117	47782140	6	-	27260156	HCC44	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	-0.40345559603357994	[287]	[225,287,194,256]	-6	hSpCas9	negative selection	6772064
47791842	47791865	6	-	27260156	HCC44	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.08456031206218767	[555]	[838,422,744,716]	1	hSpCas9	negative selection	6772065
47786603	47786626	6	+	27260156	HCC44	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.259715043125318	[345]	[540,343,632,406]	4	hSpCas9	negative selection	6836318
47782143	47782166	6	-	27260156	HCC44	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.07815153481154002	[289]	[386,336,440,241]	1	hSpCas9	negative selection	6836319
47786546	47786569	6	-	27260156	HCC44	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.09287664310712107	[1176]	[1283,1117,1680,1651]	1	hSpCas9	negative selection	6836320
47791853	47791876	6	+	27260156	G402	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.11861477423447475	[212]	[219,262,270,202]	-1	hSpCas9	negative selection	6893314
47782117	47782140	6	-	27260156	G402	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.44472289242823754	[287]	[695,655,374,237]	5	hSpCas9	negative selection	6893315
47791842	47791865	6	-	27260156	G402	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.2612870481673867	[555]	[692,577,464,545]	-3	hSpCas9	negative selection	6893316
47786603	47786626	6	+	27260156	G402	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.3599243413372464	[345]	[420,506,554,656]	4	hSpCas9	negative selection	6957569
47782143	47782166	6	-	27260156	G402	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.1761681607880825	[289]	[685,247,211,162]	-2	hSpCas9	negative selection	6957570
47786546	47786569	6	-	27260156	G402	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.653195042049955	[1176]	[2447,3101,2204,1389]	7	hSpCas9	negative selection	6957571
47791853	47791876	6	+	27260156	L33	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.21808246957129884	[212]	[302,66,172,247]	5	hSpCas9	negative selection	7014565
47782117	47782140	6	-	27260156	L33	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.32009255079287385	[287]	[425,176,185,282]	6	hSpCas9	negative selection	7014566
47791842	47791865	6	-	27260156	L33	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.29266732473373547	[555]	[566,329,393,726]	6	hSpCas9	negative selection	7014567
47786603	47786626	6	+	27260156	L33	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.403739278590044	[345]	[358,203,348,421]	8	hSpCas9	negative selection	7078820
47782143	47782166	6	-	27260156	L33	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.5185623440165648	[289]	[278,96,91,145]	-8	hSpCas9	negative selection	7078821
47786546	47786569	6	-	27260156	L33	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.08438127924688987	[1176]	[1323,507,769,1200]	1	hSpCas9	negative selection	7078822
47791853	47791876	6	+	27260156	K562	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.054925360145052116	[212]	[83,79,181,347]	0	hSpCas9	negative selection	7135816
47782117	47782140	6	-	27260156	K562	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.16450811806279853	[287]	[93,161,463,389]	2	hSpCas9	negative selection	7135817
47791842	47791865	6	-	27260156	K562	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.04540804358035039	[555]	[737,621,390,218]	0	hSpCas9	negative selection	7135818
47786603	47786626	6	+	27260156	K562	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.3758189401433485	[345]	[384,264,696,253]	5	hSpCas9	negative selection	7200071
47782143	47782166	6	-	27260156	K562	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.4654153345058959	[289]	[255,160,718,274]	6	hSpCas9	negative selection	7200072
47786546	47786569	6	-	27260156	K562	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.3914380830583235	[1176]	[1768,1611,798,1342]	5	hSpCas9	negative selection	7200073
47791853	47791876	6	+	27260156	HT29	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.046678076752784126	[212]	[301,192,291,275]	0	hSpCas9	negative selection	7257067
47782117	47782140	6	-	27260156	HT29	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.1502743233256163	[287]	[324,567,317,354]	3	hSpCas9	negative selection	7257068
47791842	47791865	6	-	27260156	HT29	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.1169963924311756	[555]	[830,722,733,654]	2	hSpCas9	negative selection	7257069
47786603	47786626	6	+	27260156	HT29	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.251453539509457	[345]	[718,465,408,427]	5	hSpCas9	negative selection	7321322
47782143	47782166	6	-	27260156	HT29	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.06570973295565419	[289]	[336,372,399,248]	-1	hSpCas9	negative selection	7321323
47786546	47786569	6	-	27260156	HT29	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.18839177897529757	[1176]	[1781,1955,1448,1391]	3	hSpCas9	negative selection	7321324
47791853	47791876	6	+	27260156	MHHES1	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.6177609047940444	[212]	[167,238,143,94]	-8	hSpCas9	negative selection	7378318
47782117	47782140	6	-	27260156	MHHES1	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	-0.05908888177372518	[287]	[360,455,181,268]	-1	hSpCas9	negative selection	7378319
47791842	47791865	6	-	27260156	MHHES1	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.20115893153628578	[555]	[740,539,796,759]	3	hSpCas9	negative selection	7378320
47786603	47786626	6	+	27260156	MHHES1	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.5946571727455904	[345]	[691,710,454,521]	8	hSpCas9	negative selection	7442573
47782143	47782166	6	-	27260156	MHHES1	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.2502439152002688	[289]	[339,269,188,294]	-5	hSpCas9	negative selection	7442574
47786546	47786569	6	-	27260156	MHHES1	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.18002267057299481	[1176]	[2016,1522,1339,1221]	3	hSpCas9	negative selection	7442575
47791853	47791876	6	+	27260156	MEWO	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.072757866159739	[212]	[197,195,175]	-1	hSpCas9	negative selection	7499569
47782117	47782140	6	-	27260156	MEWO	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.13760139953478423	[287]	[406,209,293]	3	hSpCas9	negative selection	7499570
47791842	47791865	6	-	27260156	MEWO	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.1986072952948334	[555]	[680,593,531]	4	hSpCas9	negative selection	7499571
47786603	47786626	6	+	27260156	MEWO	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	-0.14712923905593722	[345]	[379,267,245]	-3	hSpCas9	negative selection	7563824
47782143	47782166	6	-	27260156	MEWO	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.025027313536596152	[289]	[313,277,216]	0	hSpCas9	negative selection	7563825
47786546	47786569	6	-	27260156	MEWO	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.3041544569168193	[1176]	[1478,1278,1343]	6	hSpCas9	negative selection	7563826
47791853	47791876	6	+	27260156	LNCAPCLONEFGC	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.1786048795203805	[212]	[257,242,184,179]	2	hSpCas9	negative selection	7620820
47782117	47782140	6	-	27260156	LNCAPCLONEFGC	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.08931505342007318	[287]	[261,284,325,243]	1	hSpCas9	negative selection	7620821
47791842	47791865	6	-	27260156	LNCAPCLONEFGC	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.3158836280078927	[555]	[765,448,684,624]	5	hSpCas9	negative selection	7620822
47786603	47786626	6	+	27260156	LNCAPCLONEFGC	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.353884262371396	[345]	[394,362,470,385]	5	hSpCas9	negative selection	7685075
47782143	47782166	6	-	27260156	LNCAPCLONEFGC	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.1739890248698266	[289]	[255,204,241,230]	-3	hSpCas9	negative selection	7685076
47786546	47786569	6	-	27260156	LNCAPCLONEFGC	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.2515147589771747	[1176]	[1204,1286,1415,1189]	4	hSpCas9	negative selection	7685077
47791853	47791876	6	+	27260156	PANC0327	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.14211758852128598	[212]	[213,120,265,94]	-2	hSpCas9	negative selection	7742071
47782117	47782140	6	-	27260156	PANC0327	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	-0.29746483182626715	[287]	[234,121,259,228]	-4	hSpCas9	negative selection	7742072
47791842	47791865	6	-	27260156	PANC0327	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.06743741355896699	[555]	[594,340,501,660]	1	hSpCas9	negative selection	7742073
47786603	47786626	6	+	27260156	PANC0327	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.04351372614621324	[345]	[370,196,392,325]	0	hSpCas9	negative selection	7806326
47782143	47782166	6	-	27260156	PANC0327	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.57944269712325	[289]	[75,105,130,376]	-7	hSpCas9	negative selection	7806327
47786546	47786569	6	-	27260156	PANC0327	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.25843724807243107	[1176]	[995,1039,1571,1400]	4	hSpCas9	negative selection	7806328
47791853	47791876	6	+	27260156	NCIH2009	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.15597653270883605	[212]	[436,220,358]	2	hSpCas9	negative selection	7863322
47782117	47782140	6	-	27260156	NCIH2009	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.21951831856025628	[287]	[688,485,272]	3	hSpCas9	negative selection	7863323
47791842	47791865	6	-	27260156	NCIH2009	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.4738595881360633	[555]	[1183,887,1186]	6	hSpCas9	negative selection	7863324
47786603	47786626	6	+	27260156	NCIH2009	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.4743181154584976	[345]	[693,619,704]	6	hSpCas9	negative selection	7927577
47782143	47782166	6	-	27260156	NCIH2009	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.25092438594741184	[289]	[436,283,319]	-3	hSpCas9	negative selection	7927578
47786546	47786569	6	-	27260156	NCIH2009	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	-0.06313007318492136	[1176]	[1563,1269,1888]	-1	hSpCas9	negative selection	7927579
47791853	47791876	6	+	27260156	NCIH1373	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.2656097074873558	[212]	[259,260,256,97]	2	hSpCas9	negative selection	7984573
47782117	47782140	6	-	27260156	NCIH1373	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	-0.3224383779393256	[287]	[249,270,297,53]	-3	hSpCas9	negative selection	7984574
47791842	47791865	6	-	27260156	NCIH1373	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.5563747378912256	[555]	[214,383,459,161]	-5	hSpCas9	negative selection	7984575
47786603	47786626	6	+	27260156	NCIH1373	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.6715107498687947	[345]	[732,645,366,196]	6	hSpCas9	negative selection	8048828
47782143	47782166	6	-	27260156	NCIH1373	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.3305905731334635	[289]	[99,278,109,140]	-3	hSpCas9	negative selection	8048829
47786546	47786569	6	-	27260156	NCIH1373	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.013995700695192737	[1176]	[1155,1335,1392,370]	0	hSpCas9	negative selection	8048830
47791853	47791876	6	+	27260156	PATU8902	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.27621539631794434	[212]	[243,340,295,61]	-3	hSpCas9	negative selection	8105824
47782117	47782140	6	-	27260156	PATU8902	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.011540212207334699	[287]	[320,246,605,385]	0	hSpCas9	negative selection	8105825
47791842	47791865	6	-	27260156	PATU8902	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.23508078201039403	[555]	[412,353,1053,710]	-2	hSpCas9	negative selection	8105826
47786603	47786626	6	+	27260156	PATU8902	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.15338672320884905	[345]	[841,625,402,266]	1	hSpCas9	negative selection	8170079
47782143	47782166	6	-	27260156	PATU8902	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.48695410751757007	[289]	[257,374,160,403]	-5	hSpCas9	negative selection	8170080
47786546	47786569	6	-	27260156	PATU8902	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.3177511079342976	[1176]	[1884,2005,2043,2246]	3	hSpCas9	negative selection	8170081
47791853	47791876	6	+	27260156	PANC1	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.1690851151801206	[212]	[193,153,358,117]	2	hSpCas9	negative selection	8227075
47782117	47782140	6	-	27260156	PANC1	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.015902253344020734	[287]	[267,327,236,188]	0	hSpCas9	negative selection	8227076
47791842	47791865	6	-	27260156	PANC1	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.1110922673159091	[555]	[485,572,338,395]	-2	hSpCas9	negative selection	8227077
47786603	47786626	6	+	27260156	PANC1	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.4860395615247724	[345]	[438,574,385,307]	7	hSpCas9	negative selection	8291330
47782143	47782166	6	-	27260156	PANC1	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.3444595933658212	[289]	[163,201,283,142]	-5	hSpCas9	negative selection	8291331
47786546	47786569	6	-	27260156	PANC1	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.1455416549985371	[1176]	[888,1824,1089,845]	2	hSpCas9	negative selection	8291332
47791853	47791876	6	+	27260156	PANC0813	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.20790081274351324	[212]	[316,301,286,253]	3	hSpCas9	negative selection	8348326
47782117	47782140	6	-	27260156	PANC0813	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.043864499843602744	[287]	[371,325,408,292]	0	hSpCas9	negative selection	8348327
47791842	47791865	6	-	27260156	PANC0813	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.5651204345973048	[555]	[1075,1053,936,814]	8	hSpCas9	negative selection	8348328
47786603	47786626	6	+	27260156	PANC0813	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.3805368727495488	[345]	[543,581,503,488]	6	hSpCas9	negative selection	8412581
47782143	47782166	6	-	27260156	PANC0813	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.7308360539357761	[289]	[217,240,163,198]	-8	hSpCas9	negative selection	8412582
47786546	47786569	6	-	27260156	PANC0813	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.0045664135669458705	[1176]	[1585,1405,1443,1141]	0	hSpCas9	negative selection	8412583
47791853	47791876	6	+	27260156	RDES	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.030317354644628036	[212]	[126,195,364,309]	0	hSpCas9	negative selection	8469577
47782117	47782140	6	-	27260156	RDES	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.2791847720764156	[287]	[289,386,382,589]	4	hSpCas9	negative selection	8469578
47791842	47791865	6	-	27260156	RDES	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.029620771276695268	[555]	[519,675,513,946]	0	hSpCas9	negative selection	8469579
47786603	47786626	6	+	27260156	RDES	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.3528690337480524	[345]	[423,529,507,581]	5	hSpCas9	negative selection	8533832
47782143	47782166	6	-	27260156	RDES	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.1710413272805008	[289]	[255,230,237,493]	-3	hSpCas9	negative selection	8533833
47786546	47786569	6	-	27260156	RDES	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.366151504208988	[1176]	[1490,1681,1764,2101]	6	hSpCas9	negative selection	8533834
47791853	47791876	6	+	27260156	PC3	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.08232984709681723	[212]	[180,181,400,196]	1	hSpCas9	negative selection	8590828
47782117	47782140	6	-	27260156	PC3	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.13071538565976648	[287]	[171,161,631,466]	3	hSpCas9	negative selection	8590829
47791842	47791865	6	-	27260156	PC3	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.15783010726570543	[555]	[339,508,677,547]	-4	hSpCas9	negative selection	8590830
47786603	47786626	6	+	27260156	PC3	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.05205594983520806	[345]	[238,368,380,468]	1	hSpCas9	negative selection	8655083
47782143	47782166	6	-	27260156	PC3	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.7019318869517448	[289]	[138,182,198,193]	-9	hSpCas9	negative selection	8655084
47786546	47786569	6	-	27260156	PC3	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	-0.022116740955078873	[1176]	[772,1349,1649,1071]	0	hSpCas9	negative selection	8655085
47791853	47791876	6	+	27260156	PATU8988T	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.37208812705853234	[212]	[163,116,266,75]	-6	hSpCas9	negative selection	8712079
47782117	47782140	6	-	27260156	PATU8988T	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.3812865359941074	[287]	[385,570,223,283]	6	hSpCas9	negative selection	8712080
47791842	47791865	6	-	27260156	PATU8988T	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.017233108278687487	[555]	[442,602,541,542]	0	hSpCas9	negative selection	8712081
47786603	47786626	6	+	27260156	PATU8988T	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.10894500196578366	[345]	[416,383,346,290]	2	hSpCas9	negative selection	8776334
47782143	47782166	6	-	27260156	PATU8988T	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	0.04048943780914227	[289]	[360,333,200,259]	0	hSpCas9	negative selection	8776335
47786546	47786569	6	-	27260156	PATU8988T	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.27108118472310094	[1176]	[1672,1336,900,1599]	4	hSpCas9	negative selection	8776336
47791853	47791876	6	+	27260156	T47D	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.11871660332237166	[212]	[202,209,270,230]	-3	hSpCas9	negative selection	8833330
47782117	47782140	6	-	27260156	T47D	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.07952104525571402	[287]	[369,305,364,381]	1	hSpCas9	negative selection	8833331
47791842	47791865	6	-	27260156	T47D	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.06202611969775529	[555]	[656,608,600,615]	-1	hSpCas9	negative selection	8833332
47786603	47786626	6	+	27260156	T47D	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.435031558326732	[345]	[592,572,458,553]	8	hSpCas9	negative selection	8897585
47782143	47782166	6	-	27260156	T47D	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.3647876383782116	[289]	[342,308,207,183]	-7	hSpCas9	negative selection	8897586
47786546	47786569	6	-	27260156	T47D	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.20762804941904456	[1176]	[1477,1407,1740,1722]	4	hSpCas9	negative selection	8897587
47791853	47791876	6	+	27260156	SU8686	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.05225551651771787	[212]	[251,186,138,308]	0	hSpCas9	negative selection	8954581
47782117	47782140	6	-	27260156	SU8686	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	-0.03758126505774373	[287]	[212,169,350,423]	0	hSpCas9	negative selection	8954582
47791842	47791865	6	-	27260156	SU8686	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.1980293415329396	[555]	[578,520,714,751]	3	hSpCas9	negative selection	8954583
47786603	47786626	6	+	27260156	SU8686	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.4672045521289457	[345]	[464,384,398,689]	7	hSpCas9	negative selection	9018836
47782143	47782166	6	-	27260156	SU8686	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.25484450377231627	[289]	[204,249,286,220]	-4	hSpCas9	negative selection	9018837
47786546	47786569	6	-	27260156	SU8686	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.03818130803035502	[1176]	[1138,1039,1272,1392]	0	hSpCas9	negative selection	9018838
47791853	47791876	6	+	27260156	SKES1	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.006383014936464537	[212]	[175,242,157,266]	0	hSpCas9	negative selection	9075832
47782117	47782140	6	-	27260156	SKES1	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.2940614612461112	[287]	[406,509,296,232]	6	hSpCas9	negative selection	9075833
47791842	47791865	6	-	27260156	SKES1	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.11673113182144768	[555]	[682,529,722,478]	2	hSpCas9	negative selection	9075834
47786603	47786626	6	+	27260156	SKES1	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.03830661209377556	[345]	[532,358,252,301]	0	hSpCas9	negative selection	9140087
47782143	47782166	6	-	27260156	SKES1	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.2265071570754963	[289]	[285,221,265,217]	-5	hSpCas9	negative selection	9140088
47786546	47786569	6	-	27260156	SKES1	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.01773693541568444	[1176]	[1271,1527,1077,946]	0	hSpCas9	negative selection	9140089
47791853	47791876	6	+	27260156	TOV112D	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	-0.02975193120613473	[212]	[178,339,90,253]	0	hSpCas9	negative selection	9197083
47782117	47782140	6	-	27260156	TOV112D	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.28371520978854575	[287]	[240,384,352,421]	5	hSpCas9	negative selection	9197084
47791842	47791865	6	-	27260156	TOV112D	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.23572368416000627	[555]	[657,636,328,326]	-4	hSpCas9	negative selection	9197085
47786603	47786626	6	+	27260156	TOV112D	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.0021753922457850017	[345]	[318,290,359,399]	0	hSpCas9	negative selection	9261338
47782143	47782166	6	-	27260156	TOV112D	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.4254916722539399	[289]	[231,219,236,178]	-7	hSpCas9	negative selection	9261339
47786546	47786569	6	-	27260156	TOV112D	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.07127290605661774	[1176]	[1370,1489,994,1170]	1	hSpCas9	negative selection	9261340
47791853	47791876	6	+	27260156	TC71	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.027768996578484195	[212]	[261,195,220,252]	0	hSpCas9	negative selection	9318334
47782117	47782140	6	-	27260156	TC71	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.3430891156736752	[287]	[430,333,357,446]	7	hSpCas9	negative selection	9318335
47791842	47791865	6	-	27260156	TC71	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.14489764574021774	[555]	[736,615,565,721]	3	hSpCas9	negative selection	9318336
47786603	47786626	6	+	27260156	TC71	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.2813022942421919	[345]	[377,422,482,523]	6	hSpCas9	negative selection	9382589
47782143	47782166	6	-	27260156	TC71	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.2549370055482584	[289]	[235,288,243,274]	-6	hSpCas9	negative selection	9382590
47786546	47786569	6	-	27260156	TC71	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.2620500994196875	[1176]	[1480,1228,1584,1770]	6	hSpCas9	negative selection	9382591
47791853	47791876	6	+	27260156	TC32	viability	TTGGCTGGATCGGCTGCCGCTGG	OPN5	ENSG00000124818	0.05414456512260468	[212]	[240,64,205,366]	1	hSpCas9	negative selection	9439585
47782117	47782140	6	-	27260156	TC32	viability	CAAAAGGATCCCCATCTCGAAGG	OPN5	ENSG00000124818	0.4641081871034873	[287]	[305,247,604,411]	7	hSpCas9	negative selection	9439586
47791842	47791865	6	-	27260156	TC32	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.16567095318087205	[555]	[601,335,735,765]	3	hSpCas9	negative selection	9439587
47786603	47786626	6	+	27260156	TC32	viability	CAATTTAGCAGTCTGTGATCTGG	OPN5	ENSG00000124818	0.7310916995763406	[345]	[486,407,605,702]	9	hSpCas9	negative selection	9503840
47782143	47782166	6	-	27260156	TC32	viability	ATCCGCTTCCCAAGAAAGTTTGG	OPN5	ENSG00000124818	-0.2039457277948179	[289]	[247,173,302,240]	-4	hSpCas9	negative selection	9503841
47786546	47786569	6	-	27260156	TC32	viability	TTCGTCTAGAAGACATGTAAAGG	OPN5	ENSG00000124818	0.34428505316517377	[1176]	[1378,1025,1855,1501]	6	hSpCas9	negative selection	9503842
47782086	47782109	6	-	27869803	HPAFII	viability after 27 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.8714074017841938	[210]	[34,81,NaN]	-6	hSpCas9	negative selection	9596415
47791842	47791865	6	-	27869803	HPAFII	viability after 27 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.5720490376146325	[463]	[174,154,NaN]	-4	hSpCas9	negative selection	9596416
47795341	47795364	6	+	27869803	HPAFII	viability after 27 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.061828553560671295	[274]	[127,169,NaN]	0	hSpCas9	negative selection	9596417
47795428	47795451	6	-	27869803	HPAFII	viability after 27 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	0.701928756104792	[328]	[378,199,NaN]	6	hSpCas9	negative selection	9596418
47808242	47808265	6	-	27869803	HPAFII	viability after 27 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	1.9204521086255972	[82]	[354,6,NaN]	9	hSpCas9	negative selection	9596419
47808338	47808361	6	-	27869803	HPAFII	viability after 27 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	1.2983169805040153	[241]	[445,201,NaN]	9	hSpCas9	negative selection	9596420
47782086	47782109	6	-	27869803	HPAFII	viability after 15 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.7830951351543366	[210]	[87,158,NaN]	-7	hSpCas9	negative selection	9678864
47791842	47791865	6	-	27869803	HPAFII	viability after 15 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.45587027545768294	[463]	[386,348,NaN]	-5	hSpCas9	negative selection	9678865
47795341	47795364	6	+	27869803	HPAFII	viability after 15 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	-0.13768660350459608	[274]	[251,278,NaN]	-2	hSpCas9	negative selection	9678866
47795428	47795451	6	-	27869803	HPAFII	viability after 15 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	0.6407859053609937	[328]	[591,525,NaN]	7	hSpCas9	negative selection	9678867
47808242	47808265	6	-	27869803	HPAFII	viability after 15 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	1.295028259005421	[82]	[430,86,NaN]	9	hSpCas9	negative selection	9678868
47808338	47808361	6	-	27869803	HPAFII	viability after 15 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	1.246070189556301	[241]	[857,466,NaN]	9	hSpCas9	negative selection	9678869
47782086	47782109	6	-	27869803	ASPC1	viability after 36 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	0.363809619451957	[689]	[278,317,321]	3	hSpCas9	negative selection	9761313
47791842	47791865	6	-	27869803	ASPC1	viability after 36 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.3690807329528888	[1060]	[542,767,197]	3	hSpCas9	negative selection	9761314
47795341	47795364	6	+	27869803	ASPC1	viability after 36 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	-0.0769067402075726	[738]	[257,204,263]	-1	hSpCas9	negative selection	9761315
47795428	47795451	6	-	27869803	ASPC1	viability after 36 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	0.4230421500088647	[1094]	[1081,196,357]	4	hSpCas9	negative selection	9761316
47808242	47808265	6	-	27869803	ASPC1	viability after 36 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	-0.5464445513156457	[246]	[14,3,132]	-5	hSpCas9	negative selection	9761317
47808338	47808361	6	-	27869803	ASPC1	viability after 36 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	1.295365538561839	[796]	[477,1001,565]	9	hSpCas9	negative selection	9761318
47782086	47782109	6	-	27869803	PATU8988S	viability after 35 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.146078661883857	[612]	[271,173,NaN]	-1	hSpCas9	negative selection	9843762
47791842	47791865	6	-	27869803	PATU8988S	viability after 35 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.2400293979649265	[836]	[451,343,NaN]	2	hSpCas9	negative selection	9843763
47795341	47795364	6	+	27869803	PATU8988S	viability after 35 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.6681021068170676	[619]	[298,494,NaN]	7	hSpCas9	negative selection	9843764
47795428	47795451	6	-	27869803	PATU8988S	viability after 35 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	1.1539647084278097	[954]	[1025,684,NaN]	9	hSpCas9	negative selection	9843765
47808242	47808265	6	-	27869803	PATU8988S	viability after 35 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.7633730720112433	[195]	[131,135,NaN]	7	hSpCas9	negative selection	9843766
47808338	47808361	6	-	27869803	PATU8988S	viability after 35 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	0.6024583657103655	[827]	[426,585,NaN]	6	hSpCas9	negative selection	9843767
47782086	47782109	6	-	27869803	PATU8988S	viability after 31 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.14281489978912276	[612]	[183,268,NaN]	-2	hSpCas9	negative selection	9926211
47791842	47791865	6	-	27869803	PATU8988S	viability after 31 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.1859987593090635	[836]	[347,419,NaN]	2	hSpCas9	negative selection	9926212
47795341	47795364	6	+	27869803	PATU8988S	viability after 31 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.7383987798610262	[619]	[239,631,NaN]	8	hSpCas9	negative selection	9926213
47795428	47795451	6	-	27869803	PATU8988S	viability after 31 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	0.9612521079646499	[954]	[630,881,NaN]	9	hSpCas9	negative selection	9926214
47808242	47808265	6	-	27869803	PATU8988S	viability after 31 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	0.3241285703496646	[195]	[103,89,NaN]	4	hSpCas9	negative selection	9926215
47808338	47808361	6	-	27869803	PATU8988S	viability after 31 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	0.880008903808136	[827]	[516,722,NaN]	8	hSpCas9	negative selection	9926216
47782086	47782109	6	-	27869803	HPAFII	viability after 35 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-1.4757089568884774	[210]	[28,48,NaN]	-7	hSpCas9	negative selection	10008660
47791842	47791865	6	-	27869803	HPAFII	viability after 35 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.11129616361804895	[463]	[192,244,NaN]	0	hSpCas9	negative selection	10008661
47795341	47795364	6	+	27869803	HPAFII	viability after 35 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.15911305345816779	[274]	[114,200,NaN]	1	hSpCas9	negative selection	10008662
47795428	47795451	6	-	27869803	HPAFII	viability after 35 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	1.425589167212094	[328]	[437,457,NaN]	8	hSpCas9	negative selection	10008663
47808242	47808265	6	-	27869803	HPAFII	viability after 35 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	2.038377420948927	[82]	[324,0,NaN]	9	hSpCas9	negative selection	10008664
47808338	47808361	6	-	27869803	HPAFII	viability after 35 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	1.5166504987822664	[241]	[485,197,NaN]	8	hSpCas9	negative selection	10008665
47782086	47782109	6	-	27869803	HPAFII	viability after 31 days	CAGGCGCTCGTCCTGAGGCAGGG	OPN5	ENSG00000124818	-0.814734102933505	[210]	[40,95,NaN]	-5	hSpCas9	negative selection	10091109
47791842	47791865	6	-	27869803	HPAFII	viability after 31 days	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.27258762698323524	[463]	[205,225,NaN]	-2	hSpCas9	negative selection	10091110
47795341	47795364	6	+	27869803	HPAFII	viability after 31 days	CTTCGGAACCTCGTGCACCCTGG	OPN5	ENSG00000124818	0.37687351063361796	[274]	[175,226,NaN]	2	hSpCas9	negative selection	10091111
47795428	47795451	6	-	27869803	HPAFII	viability after 31 days	TCACAGCCGTTGGGAGCAAGAGG	OPN5	ENSG00000124818	1.0474798038608704	[328]	[406,353,NaN]	7	hSpCas9	negative selection	10091112
47808242	47808265	6	-	27869803	HPAFII	viability after 31 days	CACAGAGAGCTGTATGGGAATGG	OPN5	ENSG00000124818	1.96974558895346	[82]	[348,0,NaN]	9	hSpCas9	negative selection	10091113
47808338	47808361	6	-	27869803	HPAFII	viability after 31 days	CAAACCACCAGTTTGGCAACAGG	OPN5	ENSG00000124818	1.4340318951814663	[241]	[477,245,NaN]	9	hSpCas9	negative selection	10091114
47791842	47791865	6	-	28162770	P31FUJ	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.31368614849214194	[151]	[221]	3	hSpCas9	negative selection	10204897
47795542	47795565	6	+	28162770	P31FUJ	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	0.8898170822495771	[61]	[134]	8	hSpCas9	negative selection	10204898
47795438	47795461	6	-	28162770	P31FUJ	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	-0.5431423250265288	[92]	[74]	-4	hSpCas9	negative selection	10204899
47791869	47791892	6	-	28162770	P31FUJ	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.08588023096932973	[266]	[332]	0	hSpCas9	negative selection	10204900
47795280	47795303	6	-	28162770	P31FUJ	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.15951521836438157	[223]	[293]	1	hSpCas9	negative selection	10204901
47795395	47795418	6	-	28162770	P31FUJ	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.4828292480729512	[217]	[357]	5	hSpCas9	negative selection	10204902
47808268	47808291	6	-	28162770	P31FUJ	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	0.18044867539045087	[201]	[268]	2	hSpCas9	negative selection	10204903
47795298	47795321	6	-	28162770	P31FUJ	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.4333420525621308	[166]	[264]	5	hSpCas9	negative selection	10204904
47795340	47795363	6	-	28162770	P31FUJ	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.8277839484466605	[442]	[923]	8	hSpCas9	negative selection	10204905
47795524	47795547	6	+	28162770	P31FUJ	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	-2.5304827530550638	[58]	[11]	-8	hSpCas9	negative selection	10204906
47791842	47791865	6	-	28162770	TF1	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	NaN	[NaN]	[261]	1	hSpCas9	negative selection	10374263
47795542	47795565	6	+	28162770	TF1	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10374264
47795438	47795461	6	-	28162770	TF1	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10374265
47791869	47791892	6	-	28162770	TF1	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	NaN	[NaN]	[125]	1	hSpCas9	negative selection	10374266
47795280	47795303	6	-	28162770	TF1	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10374267
47795395	47795418	6	-	28162770	TF1	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	NaN	[NaN]	[283]	1	hSpCas9	negative selection	10374268
47808268	47808291	6	-	28162770	TF1	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10374269
47795298	47795321	6	-	28162770	TF1	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10374270
47795340	47795363	6	-	28162770	TF1	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	NaN	[NaN]	[463]	1	hSpCas9	negative selection	10374271
47795524	47795547	6	+	28162770	TF1	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	NaN	[NaN]	[83]	1	hSpCas9	negative selection	10374272
47791842	47791865	6	-	28162770	SKM1	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.499926396865357	[47]	[119]	5	hSpCas9	negative selection	10543629
47795542	47795565	6	+	28162770	SKM1	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	0.551456697505439	[21]	[56]	5	hSpCas9	negative selection	10543630
47795438	47795461	6	-	28162770	SKM1	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	-0.7288922936305239	[29]	[31]	-5	hSpCas9	negative selection	10543631
47791869	47791892	6	-	28162770	SKM1	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	-0.4518900696246779	[105]	[136]	-4	hSpCas9	negative selection	10543632
47795280	47795303	6	-	28162770	SKM1	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.35083489884021024	[54]	[123]	3	hSpCas9	negative selection	10543633
47795395	47795418	6	-	28162770	SKM1	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.023275707179352373	[58]	[105]	0	hSpCas9	negative selection	10543634
47808268	47808291	6	-	28162770	SKM1	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	-0.014646775964401282	[47]	[83]	0	hSpCas9	negative selection	10543635
47795298	47795321	6	-	28162770	SKM1	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	-0.5589672921882116	[39]	[47]	-4	hSpCas9	negative selection	10543636
47795340	47795363	6	-	28162770	SKM1	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.0828410689376542	[93]	[175]	0	hSpCas9	negative selection	10543637
47795524	47795547	6	+	28162770	SKM1	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	0.384449179445421	[12]	[29]	4	hSpCas9	negative selection	10543638
47791842	47791865	6	-	28162770	SKM1	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.499926396865357	[47]	[119]	5	hSpCas9	negative selection	10712995
47795542	47795565	6	+	28162770	SKM1	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	0.551456697505439	[21]	[56]	5	hSpCas9	negative selection	10712996
47795438	47795461	6	-	28162770	SKM1	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	-0.7288922936305239	[29]	[31]	-5	hSpCas9	negative selection	10712997
47791869	47791892	6	-	28162770	SKM1	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	-0.4518900696246779	[105]	[136]	-4	hSpCas9	negative selection	10712998
47795280	47795303	6	-	28162770	SKM1	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.35083489884021024	[54]	[123]	3	hSpCas9	negative selection	10712999
47795395	47795418	6	-	28162770	SKM1	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.023275707179352373	[58]	[105]	0	hSpCas9	negative selection	10713000
47808268	47808291	6	-	28162770	SKM1	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	-0.014646775964401282	[47]	[83]	0	hSpCas9	negative selection	10713001
47795298	47795321	6	-	28162770	SKM1	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	-0.5589672921882116	[39]	[47]	-4	hSpCas9	negative selection	10713002
47795340	47795363	6	-	28162770	SKM1	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.0828410689376542	[93]	[175]	0	hSpCas9	negative selection	10713003
47795524	47795547	6	+	28162770	SKM1	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	0.384449179445421	[12]	[29]	4	hSpCas9	negative selection	10713004
47791842	47791865	6	-	28162770	PL21	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.20736421210411624	[190]	[71]	-1	hSpCas9	negative selection	10882361
47795542	47795565	6	+	28162770	PL21	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	0.38722516708981547	[64]	[36]	3	hSpCas9	negative selection	10882362
47795438	47795461	6	-	28162770	PL21	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.9245051718758928	[91]	[75]	7	hSpCas9	negative selection	10882363
47791869	47791892	6	-	28162770	PL21	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	-0.19388010352044072	[317]	[120]	-1	hSpCas9	negative selection	10882364
47795280	47795303	6	-	28162770	PL21	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.07085659754435353	[244]	[111]	0	hSpCas9	negative selection	10882365
47795395	47795418	6	-	28162770	PL21	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	-0.22110303431623174	[232]	[86]	-1	hSpCas9	negative selection	10882366
47808268	47808291	6	-	28162770	PL21	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	-1.526484035455427	[138]	[20]	-7	hSpCas9	negative selection	10882367
47795298	47795321	6	-	28162770	PL21	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.9473735441093536	[111]	[93]	7	hSpCas9	negative selection	10882368
47795340	47795363	6	-	28162770	PL21	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.49160242864963166	[334]	[204]	4	hSpCas9	negative selection	10882369
47795524	47795547	6	+	28162770	PL21	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	0.9522121010457345	[37]	[31]	7	hSpCas9	negative selection	10882370
47791842	47791865	6	-	28162770	P31FUJ	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.31368614849214194	[151]	[221]	3	hSpCas9	negative selection	11051727
47795542	47795565	6	+	28162770	P31FUJ	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	0.8898170822495771	[61]	[134]	8	hSpCas9	negative selection	11051728
47795438	47795461	6	-	28162770	P31FUJ	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	-0.5431423250265288	[92]	[74]	-4	hSpCas9	negative selection	11051729
47791869	47791892	6	-	28162770	P31FUJ	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.08588023096932973	[266]	[332]	0	hSpCas9	negative selection	11051730
47795280	47795303	6	-	28162770	P31FUJ	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.15951521836438157	[223]	[293]	1	hSpCas9	negative selection	11051731
47795395	47795418	6	-	28162770	P31FUJ	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.4828292480729512	[217]	[357]	5	hSpCas9	negative selection	11051732
47808268	47808291	6	-	28162770	P31FUJ	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	0.18044867539045087	[201]	[268]	2	hSpCas9	negative selection	11051733
47795298	47795321	6	-	28162770	P31FUJ	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.4333420525621308	[166]	[264]	5	hSpCas9	negative selection	11051734
47795340	47795363	6	-	28162770	P31FUJ	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.8277839484466605	[442]	[923]	8	hSpCas9	negative selection	11051735
47795524	47795547	6	+	28162770	P31FUJ	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	-2.5304827530550638	[58]	[11]	-8	hSpCas9	negative selection	11051736
47791842	47791865	6	-	28162770	OCIAML5	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-0.10455105735688092	[108]	[182]	-1	hSpCas9	negative selection	11221093
47795542	47795565	6	+	28162770	OCIAML5	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	-0.17783673204575345	[46]	[74]	-1	hSpCas9	negative selection	11221094
47795438	47795461	6	-	28162770	OCIAML5	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.8886906024645834	[37]	[126]	7	hSpCas9	negative selection	11221095
47791869	47791892	6	-	28162770	OCIAML5	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	-0.3849405604366991	[169]	[234]	-3	hSpCas9	negative selection	11221096
47795280	47795303	6	-	28162770	OCIAML5	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.27833006639167795	[110]	[242]	2	hSpCas9	negative selection	11221097
47795395	47795418	6	-	28162770	OCIAML5	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.3838216929566741	[75]	[178]	3	hSpCas9	negative selection	11221098
47808268	47808291	6	-	28162770	OCIAML5	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	0.28057119771412187	[134]	[295]	2	hSpCas9	negative selection	11221099
47795298	47795321	6	-	28162770	OCIAML5	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.8071897122044731	[81]	[258]	7	hSpCas9	negative selection	11221100
47795340	47795363	6	-	28162770	OCIAML5	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.44810697138284405	[293]	[723]	4	hSpCas9	negative selection	11221101
47795524	47795547	6	+	28162770	OCIAML5	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	0.08380309171628753	[22]	[43]	0	hSpCas9	negative selection	11221102
47791842	47791865	6	-	28162770	EOL1	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.7759720903216557	[326]	[294]	6	hSpCas9	negative selection	11390459
47795542	47795565	6	+	28162770	EOL1	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	0.4856635303373231	[60]	[44]	4	hSpCas9	negative selection	11390460
47795438	47795461	6	-	28162770	EOL1	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.7157337567346276	[140]	[121]	6	hSpCas9	negative selection	11390461
47791869	47791892	6	-	28162770	EOL1	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	-0.41439630033242913	[596]	[235]	-3	hSpCas9	negative selection	11390462
47795280	47795303	6	-	28162770	EOL1	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.4701168339916037	[395]	[288]	4	hSpCas9	negative selection	11390463
47795395	47795418	6	-	28162770	EOL1	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.9404453984507433	[360]	[364]	7	hSpCas9	negative selection	11390464
47808268	47808291	6	-	28162770	EOL1	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	-1.1410405700570423	[179]	[42]	-6	hSpCas9	negative selection	11390465
47795298	47795321	6	-	28162770	EOL1	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.9584951034938722	[167]	[171]	8	hSpCas9	negative selection	11390466
47795340	47795363	6	-	28162770	EOL1	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	-0.08467075845884431	[470]	[233]	0	hSpCas9	negative selection	11390467
47795524	47795547	6	+	28162770	EOL1	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	0.4453799348719749	[45]	[32]	4	hSpCas9	negative selection	11390468
47791842	47791865	6	-	28162770	MOLM13	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.19007692033950563	[313]	[258]	1	hSpCas9	negative selection	11559825
47795542	47795565	6	+	28162770	MOLM13	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	-0.6734664677009624	[149]	[67]	-4	hSpCas9	negative selection	11559826
47795438	47795461	6	-	28162770	MOLM13	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.8699878251159247	[139]	[184]	6	hSpCas9	negative selection	11559827
47791869	47791892	6	-	28162770	MOLM13	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.5028077977478069	[448]	[459]	4	hSpCas9	negative selection	11559828
47795280	47795303	6	-	28162770	MOLM13	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.4981568212133751	[282]	[288]	3	hSpCas9	negative selection	11559829
47795395	47795418	6	-	28162770	MOLM13	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	1.0580885306318824	[274]	[413]	7	hSpCas9	negative selection	11559830
47808268	47808291	6	-	28162770	MOLM13	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	0.33038585779464413	[175]	[159]	2	hSpCas9	negative selection	11559831
47795298	47795321	6	-	28162770	MOLM13	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.08223568904682921	[161]	[123]	0	hSpCas9	negative selection	11559832
47795340	47795363	6	-	28162770	MOLM13	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.4390921172371438	[505]	[495]	3	hSpCas9	negative selection	11559833
47795524	47795547	6	+	28162770	MOLM13	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	0.11739213446044561	[50]	[39]	0	hSpCas9	negative selection	11559834
47791842	47791865	6	-	28162770	HEL	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.5817708147089299	[289]	[277]	5	hSpCas9	negative selection	11729191
47795542	47795565	6	+	28162770	HEL	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	-1.1743971108498326	[73]	[20]	-6	hSpCas9	negative selection	11729192
47795438	47795461	6	-	28162770	HEL	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.47027163599559113	[141]	[125]	4	hSpCas9	negative selection	11729193
47791869	47791892	6	-	28162770	HEL	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.4903339296010626	[398]	[358]	4	hSpCas9	negative selection	11729194
47795280	47795303	6	-	28162770	HEL	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.5195397672026849	[280]	[257]	4	hSpCas9	negative selection	11729195
47795395	47795418	6	-	28162770	HEL	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.6898728075914519	[270]	[279]	6	hSpCas9	negative selection	11729196
47808268	47808291	6	-	28162770	HEL	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	-0.15822776209469958	[168]	[96]	-1	hSpCas9	negative selection	11729197
47795298	47795321	6	-	28162770	HEL	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	-0.3250807622504932	[132]	[67]	-2	hSpCas9	negative selection	11729198
47795340	47795363	6	-	28162770	HEL	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.5981158405797294	[393]	[381]	5	hSpCas9	negative selection	11729199
47795524	47795547	6	+	28162770	HEL	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	0.5018762961605074	[42]	[38]	4	hSpCas9	negative selection	11729200
47791842	47791865	6	-	28162770	MV411	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	1.4523690020530011	[189]	[437]	9	hSpCas9	negative selection	11898557
47795542	47795565	6	+	28162770	MV411	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	-0.230609746021869	[77]	[55]	-2	hSpCas9	negative selection	11898558
47795438	47795461	6	-	28162770	MV411	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.5337417359394163	[81]	[99]	5	hSpCas9	negative selection	11898559
47791869	47791892	6	-	28162770	MV411	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	1.1197690256335222	[306]	[561]	8	hSpCas9	negative selection	11898560
47795280	47795303	6	-	28162770	MV411	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.6010745053974758	[215]	[275]	5	hSpCas9	negative selection	11898561
47795395	47795418	6	-	28162770	MV411	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.7156764452022487	[192]	[266]	6	hSpCas9	negative selection	11898562
47808268	47808291	6	-	28162770	MV411	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	0.08844802702161858	[114]	[102]	0	hSpCas9	negative selection	11898563
47795298	47795321	6	-	28162770	MV411	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	0.6373840690987886	[115]	[151]	6	hSpCas9	negative selection	11898564
47795340	47795363	6	-	28162770	MV411	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.6524493318763531	[360]	[477]	6	hSpCas9	negative selection	11898565
47795524	47795547	6	+	28162770	MV411	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	2.083938818499896	[20]	[74]	9	hSpCas9	negative selection	11898566
47791842	47791865	6	-	28162770	MONOMAC1	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.1952805757192064	[127]	[167]	2	hSpCas9	negative selection	12067923
47795542	47795565	6	+	28162770	MONOMAC1	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	-0.14973113228119717	[29]	[30]	-1	hSpCas9	negative selection	12067924
47795438	47795461	6	-	28162770	MONOMAC1	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.19415391026492257	[60]	[79]	2	hSpCas9	negative selection	12067925
47791869	47791892	6	-	28162770	MONOMAC1	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	-0.2778488926476509	[256]	[242]	-2	hSpCas9	negative selection	12067926
47795280	47795303	6	-	28162770	MONOMAC1	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.25613578110606106	[167]	[229]	2	hSpCas9	negative selection	12067927
47795395	47795418	6	-	28162770	MONOMAC1	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.3737117944419017	[135]	[201]	4	hSpCas9	negative selection	12067928
47808268	47808291	6	-	28162770	MONOMAC1	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	-0.5267422925386354	[92]	[73]	-4	hSpCas9	negative selection	12067929
47795298	47795321	6	-	28162770	MONOMAC1	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	-0.3080681594482976	[80]	[74]	-3	hSpCas9	negative selection	12067930
47795340	47795363	6	-	28162770	MONOMAC1	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	1.3331678459911245	[178]	[516]	9	hSpCas9	negative selection	12067931
47795524	47795547	6	+	28162770	MONOMAC1	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	2.2477479956133424	[17]	[97]	9	hSpCas9	negative selection	12067932
47791842	47791865	6	-	28162770	OCIAML2	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	0.5807984135648416	[30]	[256]	5	hSpCas9	negative selection	12237289
47795542	47795565	6	+	28162770	OCIAML2	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	0.35534077498278993	[10]	[77]	3	hSpCas9	negative selection	12237290
47795438	47795461	6	-	28162770	OCIAML2	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.9216875975365991	[11]	[125]	8	hSpCas9	negative selection	12237291
47791869	47791892	6	-	28162770	OCIAML2	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.39396904864991866	[59]	[436]	4	hSpCas9	negative selection	12237292
47795280	47795303	6	-	28162770	OCIAML2	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	-0.11832808131127992	[46]	[239]	-1	hSpCas9	negative selection	12237293
47795395	47795418	6	-	28162770	OCIAML2	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	0.8759603238794701	[28]	[294]	8	hSpCas9	negative selection	12237294
47808268	47808291	6	-	28162770	OCIAML2	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	0.05293213081485171	[19]	[114]	0	hSpCas9	negative selection	12237295
47795298	47795321	6	-	28162770	OCIAML2	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	1.0403320940352183	[19]	[227]	8	hSpCas9	negative selection	12237296
47795340	47795363	6	-	28162770	OCIAML2	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.3944405946717303	[62]	[458]	4	hSpCas9	negative selection	12237297
47795524	47795547	6	+	28162770	OCIAML2	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	0.79615671545274	[7]	[76]	7	hSpCas9	negative selection	12237298
47791842	47791865	6	-	28162770	OCIAML3	viability	CGATCCAGCCAAACACCCAGCGG	OPN5	ENSG00000124818	-1.134576021686866	[47]	[65]	-7	hSpCas9	negative selection	12406655
47795542	47795565	6	+	28162770	OCIAML3	viability	GCTGGAAATGAAACTGACAAAGG	OPN5	ENSG00000124818	-0.2500532391068018	[12]	[32]	-2	hSpCas9	negative selection	12406656
47795438	47795461	6	-	28162770	OCIAML3	viability	GAGAACACGATCACAGCCGTTGG	OPN5	ENSG00000124818	0.14295795384204313	[8]	[29]	1	hSpCas9	negative selection	12406657
47791869	47791892	6	-	28162770	OCIAML3	viability	ATCCAGCCCATCCATACCAGCGG	OPN5	ENSG00000124818	0.21073606827690305	[78]	[275]	2	hSpCas9	negative selection	12406658
47795280	47795303	6	-	28162770	OCIAML3	viability	GGTGGTCCAGAAGGAAGCATAGG	OPN5	ENSG00000124818	0.05089740085327511	[54]	[171]	0	hSpCas9	negative selection	12406659
47795395	47795418	6	-	28162770	OCIAML3	viability	GGATGTTCAGGATGAAAACCTGG	OPN5	ENSG00000124818	1.070181551547568	[61]	[392]	8	hSpCas9	negative selection	12406660
47808268	47808291	6	-	28162770	OCIAML3	viability	GCAGATTTTGCAAGTAGGGTTGG	OPN5	ENSG00000124818	0.18092580404106345	[44]	[153]	1	hSpCas9	negative selection	12406661
47795298	47795321	6	-	28162770	OCIAML3	viability	CAGACCTACCAAGGGCATGGTGG	OPN5	ENSG00000124818	-0.4615573443005136	[51]	[113]	-4	hSpCas9	negative selection	12406662
47795340	47795363	6	-	28162770	OCIAML3	viability	CAGGGTGCACGAGGTTCCGAAGG	OPN5	ENSG00000124818	0.4354695607526706	[108]	[444]	4	hSpCas9	negative selection	12406663
47795524	47795547	6	+	28162770	OCIAML3	viability	GATCCATAGCAGCCATGTGCTGG	OPN5	ENSG00000124818	-1.774579885965984	[16]	[14]	-8	hSpCas9	negative selection	12406664