Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4987
• Symbol:OPRL1
• Description:opioid related nociceptin receptor 1

DataSource: http://genomecrispr.dkfz.de/#!/results/OPRL1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
64092737	64092760	20	-	26472758	Jiyoye	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	4.88830207124249	[2]	[66]	9	hSpCas9	negative selection	113936
64097882	64097905	CHR_HSCHR20_1_CTG3	-	26472758	Jiyoye	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000277044	-0.5053617772437874	[127]	[67]	-4	hSpCas9	negative selection	113937
64097882	64097905	20	-	26472758	Jiyoye	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	-0.5053617772437874	[127]	[67]	-4	hSpCas9	negative selection	113938
64092878	64092901	20	-	26472758	Jiyoye	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-0.09073038494605956	[208]	[147]	0	hSpCas9	negative selection	113939
64097901	64097924	CHR_HSCHR20_1_CTG3	-	26472758	Jiyoye	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000277044	0.9096757220350566	[119]	[169]	6	hSpCas9	negative selection	113940
64097901	64097924	20	-	26472758	Jiyoye	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.9096757220350566	[119]	[169]	6	hSpCas9	negative selection	113941
64092768	64092791	20	-	26472758	Jiyoye	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	-0.8932195518318474	[132]	[53]	-6	hSpCas9	negative selection	113942
64092788	64092811	20	-	26472758	Jiyoye	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	1.3356221204808394	[30]	[58]	7	hSpCas9	negative selection	113943
64097849	64097872	20	-	26472758	Jiyoye	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	-0.1713608500558499	[223]	[149]	-1	hSpCas9	negative selection	113944
64097849	64097872	CHR_HSCHR20_1_CTG3	-	26472758	Jiyoye	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000277044	-0.1713608500558499	[223]	[149]	-1	hSpCas9	negative selection	113945
64098032	64098055	CHR_HSCHR20_1_CTG3	-	26472758	Jiyoye	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000277044	1.99213788222703	[8]	[26]	8	hSpCas9	negative selection	113946
64098032	64098055	20	-	26472758	Jiyoye	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	1.99213788222703	[8]	[26]	8	hSpCas9	negative selection	113947
64098095	64098118	20	-	26472758	Jiyoye	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	1.2722458014197648	[111]	[203]	7	hSpCas9	negative selection	113948
64098095	64098118	CHR_HSCHR20_1_CTG3	-	26472758	Jiyoye	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000277044	1.2722458014197648	[111]	[203]	7	hSpCas9	negative selection	113949
64092826	64092849	20	+	26472758	Jiyoye	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	-1.4360991148066735	[182]	[50]	-7	hSpCas9	negative selection	113950
64092737	64092760	20	-	26472758	KBM7	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.3886569769464647	[177,130]	[37,69]	-4	hSpCas9	negative selection	305054
64097882	64097905	CHR_HSCHR20_1_CTG3	-	26472758	KBM7	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000277044	0.2970120450733198	[583,476]	[289,317]	3	hSpCas9	negative selection	305055
64097882	64097905	20	-	26472758	KBM7	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	0.2970120450733198	[583,476]	[289,317]	3	hSpCas9	negative selection	305056
64092878	64092901	20	-	26472758	KBM7	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	0.2241075807970405	[670,448]	[277,324]	2	hSpCas9	negative selection	305057
64097901	64097924	CHR_HSCHR20_1_CTG3	-	26472758	KBM7	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000277044	0.37996356868547704	[713,340]	[271,348]	4	hSpCas9	negative selection	305058
64097901	64097924	20	-	26472758	KBM7	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.37996356868547704	[713,340]	[271,348]	4	hSpCas9	negative selection	305059
64092768	64092791	20	-	26472758	KBM7	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	-0.614684953206355	[195,165]	[85,27]	-5	hSpCas9	negative selection	305060
64092788	64092811	20	-	26472758	KBM7	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	0.27324841069163197	[234,143]	[94,114]	3	hSpCas9	negative selection	305061
64097849	64097872	20	-	26472758	KBM7	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.45163730351910414	[748,485]	[345,429]	5	hSpCas9	negative selection	305062
64097849	64097872	CHR_HSCHR20_1_CTG3	-	26472758	KBM7	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000277044	0.45163730351910414	[748,485]	[345,429]	5	hSpCas9	negative selection	305063
64098032	64098055	CHR_HSCHR20_1_CTG3	-	26472758	KBM7	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000277044	0.42563359982677695	[201,189]	[57,182]	4	hSpCas9	negative selection	305064
64098032	64098055	20	-	26472758	KBM7	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	0.42563359982677695	[201,189]	[57,182]	4	hSpCas9	negative selection	305065
64098095	64098118	20	-	26472758	KBM7	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.4702230776391092	[926,592]	[536,440]	5	hSpCas9	negative selection	305066
64098095	64098118	CHR_HSCHR20_1_CTG3	-	26472758	KBM7	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000277044	0.4702230776391092	[926,592]	[536,440]	5	hSpCas9	negative selection	305067
64092826	64092849	20	+	26472758	KBM7	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.1864468613287999	[595,440]	[339,215]	2	hSpCas9	negative selection	305068
64092737	64092760	20	-	26472758	Raji	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	1.2004929397650808	[29]	[15]	9	hSpCas9	negative selection	496172
64097882	64097905	CHR_HSCHR20_1_CTG3	-	26472758	Raji	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000277044	0.6061893923450413	[183]	[64]	6	hSpCas9	negative selection	496173
64097882	64097905	20	-	26472758	Raji	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	0.6061893923450413	[183]	[64]	6	hSpCas9	negative selection	496174
64092878	64092901	20	-	26472758	Raji	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-0.80718098812034	[376]	[49]	-6	hSpCas9	negative selection	496175
64097901	64097924	CHR_HSCHR20_1_CTG3	-	26472758	Raji	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000277044	-0.10609783205545252	[268]	[57]	-1	hSpCas9	negative selection	496176
64097901	64097924	20	-	26472758	Raji	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	-0.10609783205545252	[268]	[57]	-1	hSpCas9	negative selection	496177
64092768	64092791	20	-	26472758	Raji	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	-1.089013677429904	[109]	[11]	-7	hSpCas9	negative selection	496178
64092788	64092811	20	-	26472758	Raji	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	1.501662474485646	[34]	[22]	9	hSpCas9	negative selection	496179
64097849	64097872	20	-	26472758	Raji	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	1.060947962383315	[220]	[106]	8	hSpCas9	negative selection	496180
64097849	64097872	CHR_HSCHR20_1_CTG3	-	26472758	Raji	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000277044	1.060947962383315	[220]	[106]	8	hSpCas9	negative selection	496181
64098032	64098055	CHR_HSCHR20_1_CTG3	-	26472758	Raji	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000277044	-0.9200972010485073	[105]	[12]	-6	hSpCas9	negative selection	496182
64098032	64098055	20	-	26472758	Raji	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	-0.9200972010485073	[105]	[12]	-6	hSpCas9	negative selection	496183
64098095	64098118	20	-	26472758	Raji	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.9539939016575869	[346]	[155]	8	hSpCas9	negative selection	496184
64098095	64098118	CHR_HSCHR20_1_CTG3	-	26472758	Raji	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000277044	0.9539939016575869	[346]	[155]	8	hSpCas9	negative selection	496185
64092826	64092849	20	+	26472758	Raji	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.4751153198740865	[216]	[69]	4	hSpCas9	negative selection	496186
64092737	64092760	20	-	26472758	K562	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.19871107864174986	[120]	[88]	-1	hSpCas9	negative selection	687290
64097882	64097905	CHR_HSCHR20_1_CTG3	-	26472758	K562	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000277044	-0.12481508199927216	[309]	[239]	-1	hSpCas9	negative selection	687291
64097882	64097905	20	-	26472758	K562	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	-0.12481508199927216	[309]	[239]	-1	hSpCas9	negative selection	687292
64092878	64092901	20	-	26472758	K562	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-1.7922397429124013	[557]	[135]	-7	hSpCas9	negative selection	687293
64097901	64097924	CHR_HSCHR20_1_CTG3	-	26472758	K562	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000277044	0.8096491632634186	[318]	[471]	6	hSpCas9	negative selection	687294
64097901	64097924	20	-	26472758	K562	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.8096491632634186	[318]	[471]	6	hSpCas9	negative selection	687295
64092768	64092791	20	-	26472758	K562	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	-1.1092182269482538	[206]	[80]	-6	hSpCas9	negative selection	687296
64092788	64092811	20	-	26472758	K562	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	-0.7978920771915174	[172]	[83]	-5	hSpCas9	negative selection	687297
64097849	64097872	20	-	26472758	K562	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.8305285008463845	[418]	[628]	7	hSpCas9	negative selection	687298
64097849	64097872	CHR_HSCHR20_1_CTG3	-	26472758	K562	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000277044	0.8305285008463845	[418]	[628]	7	hSpCas9	negative selection	687299
64098032	64098055	CHR_HSCHR20_1_CTG3	-	26472758	K562	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000277044	-1.7622450026145637	[216]	[53]	-7	hSpCas9	negative selection	687300
64098032	64098055	20	-	26472758	K562	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	-1.7622450026145637	[216]	[53]	-7	hSpCas9	negative selection	687301
64098095	64098118	20	-	26472758	K562	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.13384030965935012	[636]	[589]	1	hSpCas9	negative selection	687302
64098095	64098118	CHR_HSCHR20_1_CTG3	-	26472758	K562	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000277044	0.13384030965935012	[636]	[589]	1	hSpCas9	negative selection	687303
64092826	64092849	20	+	26472758	K562	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.2971601897384201	[375]	[389]	2	hSpCas9	negative selection	687304
64092737	64092760	20	-	26627737	DLD1	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.70312182989887	[167]	[140,27,84]	7	hSpCas9	negative selection	815709
64092742	64092765	20	-	26627737	DLD1	viability	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.5359954437728953	[1133]	[506,641,413]	5	hSpCas9	negative selection	815710
64092930	64092953	20	-	26627737	DLD1	viability	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	0.8750323139391455	[580]	[273,481,260]	8	hSpCas9	negative selection	815711
64098119	64098142	20	-	26627737	DLD1	viability	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.3304575334989705	[774]	[154,250,176]	-3	hSpCas9	negative selection	815712
64098525	64098548	20	+	26627737	DLD1	viability	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.12364741127986867	[174]	[135,18,26]	1	hSpCas9	negative selection	815713
64098603	64098626	20	-	26627737	DLD1	viability	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	0.2933859432202884	[473]	[163,155,217]	3	hSpCas9	negative selection	815714
64092737	64092760	20	-	26627737	GBM cells	viability after 5 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.32347854645076235	[90]	[24,52]	-5	hSpCas9	negative selection	898024
64092742	64092765	20	-	26627737	GBM cells	viability after 5 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.25707428693238366	[982]	[608,650]	4	hSpCas9	negative selection	898025
64092930	64092953	20	-	26627737	GBM cells	viability after 5 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.5972393588776145	[377]	[136,130]	-7	hSpCas9	negative selection	898026
64098119	64098142	20	-	26627737	GBM cells	viability after 5 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	0.9077920262321385	[242]	[245,242]	9	hSpCas9	negative selection	898027
64098525	64098548	20	+	26627737	GBM cells	viability after 5 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.058112469734939554	[119]	[68,64]	0	hSpCas9	negative selection	898028
64098603	64098626	20	-	26627737	GBM cells	viability after 5 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-0.23703362314351156	[277]	[116,135]	-4	hSpCas9	negative selection	898029
64092737	64092760	20	-	26627737	GBM cells	viability after 13 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.6197367934826272	[90]	[19,41]	-6	hSpCas9	negative selection	980339
64092742	64092765	20	-	26627737	GBM cells	viability after 13 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.15165524370654393	[982]	[715,491]	2	hSpCas9	negative selection	980340
64092930	64092953	20	-	26627737	GBM cells	viability after 13 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.9371859701000258	[377]	[121,94]	-8	hSpCas9	negative selection	980341
64098119	64098142	20	-	26627737	GBM cells	viability after 13 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	0.7217231900508413	[242]	[260,181]	8	hSpCas9	negative selection	980342
64098525	64098548	20	+	26627737	GBM cells	viability after 13 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.08035073643154356	[119]	[91,49]	1	hSpCas9	negative selection	980343
64098603	64098626	20	-	26627737	GBM cells	viability after 13 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-0.11652382546738575	[277]	[126,148]	-1	hSpCas9	negative selection	980344
64092737	64092760	20	-	26627737	GBM cells	viability after 21 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.46120295416091794	[90]	[37,33]	-4	hSpCas9	negative selection	1062654
64092742	64092765	20	-	26627737	GBM cells	viability after 21 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-0.07601611638487027	[982]	[526,487]	0	hSpCas9	negative selection	1062655
64092930	64092953	20	-	26627737	GBM cells	viability after 21 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.14837656412670003	[377]	[201,169]	-1	hSpCas9	negative selection	1062656
64098119	64098142	20	-	26627737	GBM cells	viability after 21 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	0.688925786134716	[242]	[216,208]	7	hSpCas9	negative selection	1062657
64098525	64098548	20	+	26627737	GBM cells	viability after 21 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	-0.29873684142966095	[119]	[52,52]	-3	hSpCas9	negative selection	1062658
64098603	64098626	20	-	26627737	GBM cells	viability after 21 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	0.0206693442406225	[277]	[159,146]	0	hSpCas9	negative selection	1062659
64092737	64092760	20	-	26627737	RPE1	viability after 9 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.39162678151846797	[496]	[108,130]	-3	hSpCas9	negative selection	1144969
64092742	64092765	20	-	26627737	RPE1	viability after 9 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-0.046175406399266095	[4018]	[1139,1319]	0	hSpCas9	negative selection	1144970
64092930	64092953	20	-	26627737	RPE1	viability after 9 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.5082479211131999	[1203]	[240,295]	-4	hSpCas9	negative selection	1144971
64098119	64098142	20	-	26627737	RPE1	viability after 9 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	0.7260604676244191	[1096]	[671,433]	5	hSpCas9	negative selection	1144972
64098525	64098548	20	+	26627737	RPE1	viability after 9 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.46957559160760254	[352]	[135,174]	3	hSpCas9	negative selection	1144973
64098603	64098626	20	-	26627737	RPE1	viability after 9 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-1.3552334600180183	[1234]	[120,189]	-7	hSpCas9	negative selection	1144974
64092737	64092760	20	-	26627737	RPE1	viability after 12 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.18289591351284573	[496]	[104,130]	-1	hSpCas9	negative selection	1227284
64092742	64092765	20	-	26627737	RPE1	viability after 12 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-0.1229781296582999	[4018]	[822,1169]	-1	hSpCas9	negative selection	1227285
64092930	64092953	20	-	26627737	RPE1	viability after 12 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.13755554029773054	[1203]	[261,327]	-1	hSpCas9	negative selection	1227286
64098119	64098142	20	-	26627737	RPE1	viability after 12 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	0.9528105510254041	[1096]	[688,444]	6	hSpCas9	negative selection	1227287
64098525	64098548	20	+	26627737	RPE1	viability after 12 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	-0.09029076584522433	[352]	[74,103]	0	hSpCas9	negative selection	1227288
64098603	64098626	20	-	26627737	RPE1	viability after 12 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-1.0219197415405814	[1234]	[91,238]	-6	hSpCas9	negative selection	1227289
64092737	64092760	20	-	26627737	RPE1	viability after 15 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.3834305021441593	[496]	[63,149]	-2	hSpCas9	negative selection	1309599
64092742	64092765	20	-	26627737	RPE1	viability after 15 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-0.17416532421942055	[4018]	[1001,1012]	-1	hSpCas9	negative selection	1309600
64092930	64092953	20	-	26627737	RPE1	viability after 15 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.3263412658640169	[1203]	[263,278]	-2	hSpCas9	negative selection	1309601
64098119	64098142	20	-	26627737	RPE1	viability after 15 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	0.8817815731093188	[1096]	[638,506]	5	hSpCas9	negative selection	1309602
64098525	64098548	20	+	26627737	RPE1	viability after 15 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	1.0106882834996402	[352]	[161,238]	6	hSpCas9	negative selection	1309603
64098603	64098626	20	-	26627737	RPE1	viability after 15 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-2.4145753998258184	[1234]	[35,93]	-8	hSpCas9	negative selection	1309604
64092737	64092760	20	-	26627737	RPE1	viability after 18 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.36633676910848534	[496]	[119,86]	-2	hSpCas9	negative selection	1391914
64092742	64092765	20	-	26627737	RPE1	viability after 18 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-0.009712082102250275	[4018]	[1013,1144]	0	hSpCas9	negative selection	1391915
64092930	64092953	20	-	26627737	RPE1	viability after 18 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.4544294317014891	[1203]	[167,310]	-3	hSpCas9	negative selection	1391916
64098119	64098142	20	-	26627737	RPE1	viability after 18 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	1.057883760475766	[1096]	[523,714]	6	hSpCas9	negative selection	1391917
64098525	64098548	20	+	26627737	RPE1	viability after 18 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	1.1639318733169488	[352]	[182,245]	6	hSpCas9	negative selection	1391918
64098603	64098626	20	-	26627737	RPE1	viability after 18 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-1.3373211282277586	[1234]	[128,134]	-7	hSpCas9	negative selection	1391919
64092737	64092760	20	-	26627737	HeLa	viability after 8 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.2461522573206174	[115]	[154,36,11]	2	hSpCas9	negative selection	1474229
64092742	64092765	20	-	26627737	HeLa	viability after 8 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.31986493899433177	[1509]	[957,893,650]	3	hSpCas9	negative selection	1474230
64092930	64092953	20	-	26627737	HeLa	viability after 8 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.7537812077836353	[1082]	[166,386,260]	-6	hSpCas9	negative selection	1474231
64098119	64098142	20	-	26627737	HeLa	viability after 8 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.3838581634292908	[998]	[358,399,251]	-4	hSpCas9	negative selection	1474232
64098525	64098548	20	+	26627737	HeLa	viability after 8 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.11857955615163474	[224]	[139,45,137]	1	hSpCas9	negative selection	1474233
64098603	64098626	20	-	26627737	HeLa	viability after 8 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-0.3426605819430625	[509]	[250,178,115]	-3	hSpCas9	negative selection	1474234
64092737	64092760	20	-	26627737	HeLa	viability after 12 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-1.1466388468345032	[115]	[50,0,15]	-8	hSpCas9	negative selection	1556544
64092742	64092765	20	-	26627737	HeLa	viability after 12 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-0.1449322988898869	[1509]	[627,488,585]	-1	hSpCas9	negative selection	1556545
64092930	64092953	20	-	26627737	HeLa	viability after 12 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.836418565188936	[1082]	[329,271,149]	-6	hSpCas9	negative selection	1556546
64098119	64098142	20	-	26627737	HeLa	viability after 12 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-1.3074448560401082	[998]	[188,157,154]	-8	hSpCas9	negative selection	1556547
64098525	64098548	20	+	26627737	HeLa	viability after 12 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.2526890499963296	[224]	[136,92,104]	2	hSpCas9	negative selection	1556548
64098603	64098626	20	-	26627737	HeLa	viability after 12 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-0.9965697850980484	[509]	[180,30,114]	-7	hSpCas9	negative selection	1556549
64092737	64092760	20	-	26627737	HeLa	viability after 15 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	1.2392366999345847	[115]	[251,0,76]	8	hSpCas9	negative selection	1638859
64092742	64092765	20	-	26627737	HeLa	viability after 15 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-0.04735472992817291	[1509]	[677,613,482]	0	hSpCas9	negative selection	1638860
64092930	64092953	20	-	26627737	HeLa	viability after 15 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-1.6806559430987797	[1082]	[197,61,152]	-8	hSpCas9	negative selection	1638861
64098119	64098142	20	-	26627737	HeLa	viability after 15 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.9450945581488313	[998]	[194,274,159]	-7	hSpCas9	negative selection	1638862
64098525	64098548	20	+	26627737	HeLa	viability after 15 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	-0.7710968370687241	[224]	[13,51,98]	-6	hSpCas9	negative selection	1638863
64098603	64098626	20	-	26627737	HeLa	viability after 15 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-1.0433131546278442	[509]	[114,122,60]	-7	hSpCas9	negative selection	1638864
64092737	64092760	20	-	26627737	HeLa	viability after 18 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	1.3668388162595146	[115]	[188,0,76]	8	hSpCas9	negative selection	1721174
64092742	64092765	20	-	26627737	HeLa	viability after 18 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-0.05340467377675817	[1509]	[439,520,482]	0	hSpCas9	negative selection	1721175
64092930	64092953	20	-	26627737	HeLa	viability after 18 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-1.6503542536114713	[1082]	[133,56,152]	-8	hSpCas9	negative selection	1721176
64098119	64098142	20	-	26627737	HeLa	viability after 18 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.9367073151333165	[998]	[136,222,159]	-7	hSpCas9	negative selection	1721177
64098525	64098548	20	+	26627737	HeLa	viability after 18 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	-0.7280706222222224	[224]	[10,44,98]	-6	hSpCas9	negative selection	1721178
64098603	64098626	20	-	26627737	HeLa	viability after 18 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-1.0643676429420887	[509]	[74,100,60]	-7	hSpCas9	negative selection	1721179
64092737	64092760	20	-	26627737	HCT116	viability after 6 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.37041787899008227	[278]	[60,18]	-2	hSpCas9	negative selection	1803489
64092742	64092765	20	-	26627737	HCT116	viability after 6 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-0.4458567289282873	[2327]	[307,246]	-3	hSpCas9	negative selection	1803490
64092930	64092953	20	-	26627737	HCT116	viability after 6 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-1.3238637814202707	[1492]	[212,27]	-6	hSpCas9	negative selection	1803491
64098119	64098142	20	-	26627737	HCT116	viability after 6 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	2.364622229182936	[727]	[591,587]	9	hSpCas9	negative selection	1803492
64098525	64098548	20	+	26627737	HCT116	viability after 6 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	-3.3151590478288258	[504]	[16,2]	-9	hSpCas9	negative selection	1803493
64098603	64098626	20	-	26627737	HCT116	viability after 6 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-0.18179903603793934	[1100]	[198,126]	-1	hSpCas9	negative selection	1803494
64092737	64092760	20	-	26627737	HCT116	viability after 8 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	1.2176621707440796	[71]	[74,67,132]	8	hSpCas9	negative selection	1885804
64092742	64092765	20	-	26627737	HCT116	viability after 8 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.2052201969704679	[1198]	[679,712,888]	2	hSpCas9	negative selection	1885805
64092930	64092953	20	-	26627737	HCT116	viability after 8 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.059400607366665525	[567]	[173,191,529]	0	hSpCas9	negative selection	1885806
64098119	64098142	20	-	26627737	HCT116	viability after 8 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.060693384606542944	[555]	[299,257,322]	0	hSpCas9	negative selection	1885807
64098525	64098548	20	+	26627737	HCT116	viability after 8 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.5178740212965132	[108]	[47,96,111]	5	hSpCas9	negative selection	1885808
64098603	64098626	20	-	26627737	HCT116	viability after 8 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	0.06820550742850698	[252]	[139,121,175]	0	hSpCas9	negative selection	1885809
64092737	64092760	20	-	26627737	HCT116	viability after 9 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.4337600372988335	[278]	[5,93]	-3	hSpCas9	negative selection	1968119
64092742	64092765	20	-	26627737	HCT116	viability after 9 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-0.0841087755719967	[2327]	[715,483]	0	hSpCas9	negative selection	1968120
64092930	64092953	20	-	26627737	HCT116	viability after 9 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.4034471585415994	[1492]	[411,213]	-3	hSpCas9	negative selection	1968121
64098119	64098142	20	-	26627737	HCT116	viability after 9 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	0.6241497182731142	[727]	[226,356]	4	hSpCas9	negative selection	1968122
64098525	64098548	20	+	26627737	HCT116	viability after 9 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	-0.11405209659793802	[504]	[199,64]	-1	hSpCas9	negative selection	1968123
64098603	64098626	20	-	26627737	HCT116	viability after 9 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-0.9637025259169711	[1100]	[219,95]	-6	hSpCas9	negative selection	1968124
64092737	64092760	20	-	26627737	HCT116	viability after 12 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	1.0660470426954594	[71]	[63,37,135]	8	hSpCas9	negative selection	2050434
64092742	64092765	20	-	26627737	HCT116	viability after 12 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.096344321041413	[1198]	[620,735,669]	1	hSpCas9	negative selection	2050435
64092930	64092953	20	-	26627737	HCT116	viability after 12 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.179859898876653	[567]	[253,206,328]	-2	hSpCas9	negative selection	2050436
64098119	64098142	20	-	26627737	HCT116	viability after 12 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.1145267272190984	[555]	[205,298,310]	-1	hSpCas9	negative selection	2050437
64098525	64098548	20	+	26627737	HCT116	viability after 12 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.5455583220169895	[108]	[69,123,58]	5	hSpCas9	negative selection	2050438
64098603	64098626	20	-	26627737	HCT116	viability after 12 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	0.2714056914172027	[252]	[120,246,118]	2	hSpCas9	negative selection	2050439
64092737	64092760	20	-	26627737	HCT116	viability after 15 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.018307268552759215	[71]	[84,13,31]	0	hSpCas9	negative selection	2132749
64092742	64092765	20	-	26627737	HCT116	viability after 15 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.1690929756006605	[1198]	[708,774,829]	1	hSpCas9	negative selection	2132750
64092930	64092953	20	-	26627737	HCT116	viability after 15 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.1972129890381389	[567]	[461,197,215]	-2	hSpCas9	negative selection	2132751
64098119	64098142	20	-	26627737	HCT116	viability after 15 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.0668308074887688	[555]	[556,145,242]	0	hSpCas9	negative selection	2132752
64098525	64098548	20	+	26627737	HCT116	viability after 15 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	1.1474630104009595	[108]	[79,200,127]	8	hSpCas9	negative selection	2132753
64098603	64098626	20	-	26627737	HCT116	viability after 15 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-0.3384584428146126	[252]	[132,103,109]	-4	hSpCas9	negative selection	2132754
64092737	64092760	20	-	26627737	HCT116	viability after 18 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	1.1166805454684376	[71]	[42,6,185]	8	hSpCas9	negative selection	2215064
64092742	64092765	20	-	26627737	HCT116	viability after 18 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.02684162544902935	[1198]	[416,632,724]	0	hSpCas9	negative selection	2215065
64092930	64092953	20	-	26627737	HCT116	viability after 18 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	0.5577648692079848	[567]	[452,243,531]	5	hSpCas9	negative selection	2215066
64098119	64098142	20	-	26627737	HCT116	viability after 18 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.07971627959006189	[555]	[309,171,287]	0	hSpCas9	negative selection	2215067
64098525	64098548	20	+	26627737	HCT116	viability after 18 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.7951466132525153	[108]	[31,169,65]	6	hSpCas9	negative selection	2215068
64098603	64098626	20	-	26627737	HCT116	viability after 18 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	0.055714643174251594	[252]	[114,143,120]	0	hSpCas9	negative selection	2215069
64084527	64084550	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAAAATGCTGAGACCCCACTGG	OPRL1	ENSG00000125510	1.8859156216296409	[32,84]	[22,74]	6	dCas9-VP64	positive selection	2388082
64084486	64084509	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAAATATCTTTCCTACCCGATGG	OPRL1	ENSG00000125510	1.0243839315839691	[10,25]	[9,5]	4	dCas9-VP64	positive selection	2388083
64084464	64084487	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCTGATCAACTCAGTTGTAGG	OPRL1	ENSG00000125510	-0.8443201660869435	[968,859]	[89,134]	-5	dCas9-VP64	positive selection	2388084
64084855	64084878	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCAGGAGCTAAGGAGGGGCGG	OPRL1	ENSG00000125510	-1.5681762664006311	[4,70]	[2,1]	-8	dCas9-VP64	positive selection	2410816
64084904	64084927	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAGCAAGCAGGGGGTGTAGGG	OPRL1	ENSG00000125510	0.23275852788915863	[29,33]	[5,9]	1	dCas9-VP64	positive selection	2410817
64084834	64084857	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGGCGTTAGCCGCCGCTGGGG	OPRL1	ENSG00000125510	2.039946989051098	[22,15]	[20,13]	7	dCas9-VP64	positive selection	2410818
64084527	64084550	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAAAATGCTGAGACCCCACTGG	OPRL1	ENSG00000125510	-0.7431729863735097	[73,241]	[20,38]	-7	dCas9-VP64	positive selection	2483337
64084486	64084509	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAAATATCTTTCCTACCCGATGG	OPRL1	ENSG00000125510	0.10728295126154822	[65,158]	[58,19]	0	dCas9-VP64	positive selection	2483338
64084464	64084487	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCTGATCAACTCAGTTGTAGG	OPRL1	ENSG00000125510	-0.26243972968152707	[225,426]	[132,45]	-2	dCas9-VP64	positive selection	2483339
64084855	64084878	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCAGGAGCTAAGGAGGGGCGG	OPRL1	ENSG00000125510	0.09813085369875618	[24,30]	[11,6]	0	dCas9-VP64	positive selection	2506071
64084904	64084927	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAGCAAGCAGGGGGTGTAGGG	OPRL1	ENSG00000125510	-0.24776848855082845	[42,102]	[15,22]	-2	dCas9-VP64	positive selection	2506072
64084834	64084857	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGGCGTTAGCCGCCGCTGGGG	OPRL1	ENSG00000125510	0.04111067102354893	[41,11]	[6,9]	0	dCas9-VP64	positive selection	2506073
64092742	64092765	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.17488591636522077	[5,5]	[5,4]	3	hSpCas9	positive selection	3007456
64092843	64092866	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGAGGGGCAGGAAGGCGCCGTGG	OPRL1	ENSG00000125510	-0.011803999756682337	[2,2]	[2,1]	0	hSpCas9	positive selection	3007457
64092737	64092760	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.13693474763790048	[2,2]	[2,1]	-2	hSpCas9	positive selection	3007458
64092817	64092840	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATTGAGCAGCAGATGCGGGGG	OPRL1	ENSG00000125510	-0.6283111718330534	[3,3]	[2,0]	-7	hSpCas9	positive selection	3007459
64092742	64092765	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.35388810554053357	[5,5]	[4,4]	6	hSpCas9	positive selection	3075314
64092843	64092866	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGAGGGGCAGGAAGGCGCCGTGG	OPRL1	ENSG00000125510	-0.31673948237526617	[2,2]	[0,1]	-5	hSpCas9	positive selection	3075315
64092737	64092760	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.3630763348982743	[2,2]	[1,2]	6	hSpCas9	positive selection	3075316
64092817	64092840	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATTGAGCAGCAGATGCGGGGG	OPRL1	ENSG00000125510	1.0474814736701672	[3,3]	[3,6]	9	hSpCas9	positive selection	3075317
64098101	64098124		-	24336571	A375	resistance to PLX after 7 days	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.15639216418992252	[6,8]	[9,7]	5	hSpCas9	positive selection	3132506
64098785	64098808		-	24336571	A375	resistance to PLX after 7 days	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.21491473621014703	[9,8]	[9,11]	6	hSpCas9	positive selection	3132507
64098042	64098065		-	24336571	A375	resistance to PLX after 7 days	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.23484587485282327	[10,13]	[15,12]	7	hSpCas9	positive selection	3132508
64098101	64098124		-	24336571	A375	resistance to PLX after 14 days	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.769231411645146	[8,4]	[3,6]	6	hSpCas9	positive selection	3190299
64098785	64098808		-	24336571	A375	resistance to PLX after 14 days	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.9962452291683763	[9,9]	[7,9]	7	hSpCas9	positive selection	3190300
64098042	64098065		-	24336571	A375	resistance to PLX after 14 days	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.5398857583008476	[10,15]	[3,3]	-6	hSpCas9	positive selection	3190301
64098101	64098124		-	24336571	A375	viability after 7 days	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.779043389812399	[14]	[6,8]	-8	hSpCas9	negative selection	3248092
64098785	64098808		-	24336571	A375	viability after 7 days	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	-0.3843273982368035	[12]	[9,8]	-5	hSpCas9	negative selection	3248093
64098042	64098065		-	24336571	A375	viability after 7 days	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.3287893419012194	[9]	[10,13]	5	hSpCas9	negative selection	3248094
64098101	64098124		-	24336571	A375	viability after 14 days	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.8897005086995986	[14]	[8,4]	-8	hSpCas9	negative selection	3305885
64098785	64098808		-	24336571	A375	viability after 14 days	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	-0.2969788361775915	[12]	[9,9]	-4	hSpCas9	negative selection	3305886
64098042	64098065		-	24336571	A375	viability after 14 days	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.44068892769999	[9]	[10,15]	5	hSpCas9	negative selection	3305887
64092932	64092955	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	0.5708256842626168	[102,102]	[0,0]	3	hSpCas9	positive selection	3383065
64098559	64098582	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	1.4244361972810935	[56,56]	[0,0]	6	hSpCas9	positive selection	3383066
64092756	64092779	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.21293209208738176	[131,131]	[0,0]	1	hSpCas9	positive selection	3383067
64092742	64092765	20	-	26780180	HT29	viability (Avana library 4 designs)	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-0.260379031284332	[]	[]	-4	hSpCas9	negative selection	3445390
64092843	64092866	20	-	26780180	HT29	viability (Avana library 4 designs)	CGAGGGGCAGGAAGGCGCCGTGG	OPRL1	ENSG00000125510	2.53198761088681	[]	[]	8	hSpCas9	negative selection	3445391
64092737	64092760	20	-	26780180	HT29	viability (Avana library 4 designs)	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	1.13387698250675	[]	[]	4	hSpCas9	negative selection	3445392
64092817	64092840	20	-	26780180	HT29	viability (Avana library 4 designs)	GCATTGAGCAGCAGATGCGGGGG	OPRL1	ENSG00000125510	1.12006957762305	[]	[]	4	hSpCas9	negative selection	3445393
64092737	64092760	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-2.43824572278562	[]	[]	-3	hSpCas9	negative selection	3538097
64092817	64092840	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATTGAGCAGCAGATGCGGGGG	OPRL1	ENSG00000125510	1.6286281488202	[]	[]	2	hSpCas9	negative selection	3538098
64092843	64092866	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAGGGGCAGGAAGGCGCCGTGG	OPRL1	ENSG00000125510	-0.994875371269721	[]	[]	-1	hSpCas9	negative selection	3538099
64092742	64092765	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	2.99499498390371	[]	[]	4	hSpCas9	negative selection	3538100
64092859	64092882	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGGTGACCTTGAGCCCGAGGGG	OPRL1	ENSG00000125510	3.54233448006527	[]	[]	5	hSpCas9	negative selection	3538101
64092878	64092901	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	4.99558263822464	[]	[]	8	hSpCas9	negative selection	3538102
64092737	64092760	20	-	26780180	A375	viability (Avana lentiGuide)	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	3.5042348419982	[]	[]	3	hSpCas9	negative selection	3646756
64092817	64092840	20	-	26780180	A375	viability (Avana lentiGuide)	GCATTGAGCAGCAGATGCGGGGG	OPRL1	ENSG00000125510	-1.44637753398798	[]	[]	-2	hSpCas9	negative selection	3646757
64092843	64092866	20	-	26780180	A375	viability (Avana lentiGuide)	CGAGGGGCAGGAAGGCGCCGTGG	OPRL1	ENSG00000125510	2.63639815018019	[]	[]	3	hSpCas9	negative selection	3646758
64092742	64092765	20	-	26780180	A375	viability (Avana lentiGuide)	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	-2.75581166296124	[]	[]	-5	hSpCas9	negative selection	3646759
64092859	64092882	20	-	26780180	A375	viability (Avana lentiGuide)	ATGGTGACCTTGAGCCCGAGGGG	OPRL1	ENSG00000125510	9.11643350629144	[]	[]	6	hSpCas9	negative selection	3646760
64092878	64092901	20	-	26780180	A375	viability (Avana lentiGuide)	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	4.31849915794241	[]	[]	4	hSpCas9	negative selection	3646761
64092737	64092760	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.7933637093477922	[4]	[2,2]	-8	hSpCas9	positive selection	3755415
64092817	64092840	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATTGAGCAGCAGATGCGGGGG	OPRL1	ENSG00000125510	-0.09916769370649767	[4]	[3,3]	-2	hSpCas9	positive selection	3755416
64092843	64092866	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAGGGGCAGGAAGGCGCCGTGG	OPRL1	ENSG00000125510	0.12628066236391622	[2]	[2,3]	3	hSpCas9	positive selection	3755417
64092742	64092765	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.17159662255818184	[6]	[6,6]	5	hSpCas9	positive selection	3755418
64092859	64092882	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGGTGACCTTGAGCCCGAGGGG	OPRL1	ENSG00000125510	0.14318475484711118	[4]	[5,5]	4	hSpCas9	positive selection	3755419
64092878	64092901	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	0.21362998441949438	[4]	[5,4]	6	hSpCas9	positive selection	3755420
64092737	64092760	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.1678212752156235	[4]	[3,3]	-2	hSpCas9	positive selection	3864022
64092817	64092840	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATTGAGCAGCAGATGCGGGGG	OPRL1	ENSG00000125510	-0.585931286712269	[5]	[2,2]	-6	hSpCas9	positive selection	3864023
64092843	64092866	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAGGGGCAGGAAGGCGCCGTGG	OPRL1	ENSG00000125510	-0.8760508664961215	[3]	[0,1]	-8	hSpCas9	positive selection	3864024
64092742	64092765	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.28145451474766225	[6]	[6,6]	7	hSpCas9	positive selection	3864025
64092859	64092882	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGGTGACCTTGAGCCCGAGGGG	OPRL1	ENSG00000125510	-0.24903756203944777	[5]	[3,3]	-3	hSpCas9	positive selection	3864026
64092878	64092901	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	0.11757780844422738	[4]	[4,3]	2	hSpCas9	positive selection	3864027
64098101	64098124	20	-	26780180	A375	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	1.459768741309	[]	[]	8	hSpCas9	negative selection	3975162
64098785	64098808	20	-	26780180	A375	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.625421629812484	[]	[]	2	hSpCas9	negative selection	3975163
64098559	64098582	20	+	26780180	A375	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.8252652767355	[]	[]	3	hSpCas9	negative selection	3975164
64092756	64092779	20	+	26780180	A375	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	1.5783638937956	[]	[]	8	hSpCas9	negative selection	3975165
64098042	64098065	20	-	26780180	A375	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.757659303006942	[]	[]	3	hSpCas9	negative selection	3975166
64092932	64092955	20	+	26780180	A375	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	1.19261098943423	[]	[]	6	hSpCas9	negative selection	3975167
64098101	64098124	20	-	26780180	HT29	viability (GeCKOv2 library)	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	1.26264727943088	[]	[]	6	hSpCas9	negative selection	4083128
64098785	64098808	20	-	26780180	HT29	viability (GeCKOv2 library)	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	-0.0163734103618455	[]	[]	0	hSpCas9	negative selection	4083129
64098559	64098582	20	+	26780180	HT29	viability (GeCKOv2 library)	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	1.11022759725317	[]	[]	5	hSpCas9	negative selection	4083130
64092756	64092779	20	+	26780180	HT29	viability (GeCKOv2 library)	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	2.02213100494584	[]	[]	9	hSpCas9	negative selection	4083131
64098042	64098065	20	-	26780180	HT29	viability (GeCKOv2 library)	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.833714260812545	[]	[]	3	hSpCas9	negative selection	4083132
64092932	64092955	20	+	26780180	HT29	viability (GeCKOv2 library)	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	1.26190005892078	[]	[]	6	hSpCas9	negative selection	4083133
64098101	64098124	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.15718109994889373	[2]	[1,2]	4	hSpCas9	positive selection	4157299
64098785	64098808	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	-0.07381288604040817	[3]	[1,3]	-2	hSpCas9	positive selection	4157300
64098042	64098065	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.28414433357378077	[3]	[1,1]	-6	hSpCas9	positive selection	4157301
64098101	64098124	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.16997716713030597	[2]	[0,0,0,0]	-2	hSpCas9	positive selection	4221321
64098785	64098808	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	-0.5513442620543106	[3]	[0,0,0,0]	-7	hSpCas9	positive selection	4221322
64098042	64098065	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.4877934263107254	[3]	[4,1,3,0]	3	hSpCas9	positive selection	4221323
64098785	64098808	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.07207457364972558	[3]	[3,2]	1	hSpCas9	positive selection	4287102
64098101	64098124	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.05305443197173132	[2]	[3,0]	1	hSpCas9	positive selection	4287103
64098042	64098065	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.009375699685030076	[3]	[3,1]	0	hSpCas9	positive selection	4287104
64092932	64092955	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.5659532227912699	[2]	[1,0]	-8	hSpCas9	positive selection	4351357
64098559	64098582	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.12377801270027944	[1]	[1,0]	-2	hSpCas9	positive selection	4351358
64092756	64092779	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.09390576198692382	[2]	[2,1]	-2	hSpCas9	positive selection	4351359
64092818	64092840	20	-	27760321	OCIAML3	viability	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	-0.2358477324116817	[643,547]	[275,548]	-3	hSpCas9	negative selection	4424680
64092918	64092940	20	-	27760321	OCIAML3	viability	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	0.4187229733155765	[794,661]	[793,711]	5	hSpCas9	negative selection	4424681
64097981	64098003	20	-	27760321	OCIAML3	viability	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	0.7614167039341486	[411,300]	[366,599]	8	hSpCas9	negative selection	4424682
64098031	64098053	20	-	27760321	OCIAML3	viability	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	-0.9695568038410151	[462,420]	[165,189]	-7	hSpCas9	negative selection	4424683
64098101	64098123	20	-	27760321	OCIAML3	viability	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.2802856971417297	[429,336]	[174,336]	-3	hSpCas9	negative selection	4424684
64092818	64092840	20	-	27760321	OCIAML2	viability	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	0.3016145782918727	[643,547]	[489,726]	4	hSpCas9	negative selection	4508143
64092918	64092940	20	-	27760321	OCIAML2	viability	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	0.14803082368626552	[794,661]	[632,672]	2	hSpCas9	negative selection	4508144
64097981	64098003	20	-	27760321	OCIAML2	viability	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	0.12014619975091914	[411,300]	[221,426]	1	hSpCas9	negative selection	4508145
64098031	64098053	20	-	27760321	OCIAML2	viability	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	0.47777280585454657	[462,420]	[384,645]	6	hSpCas9	negative selection	4508146
64098101	64098123	20	-	27760321	OCIAML2	viability	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.14289019585132612	[429,336]	[344,333]	1	hSpCas9	negative selection	4508147
64092818	64092840	20	-	27760321	MV411	viability	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	-1.0050714735193804	[643,547]	[84,360]	-6	hSpCas9	negative selection	4591606
64092918	64092940	20	-	27760321	MV411	viability	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	-0.3992020957227734	[794,661]	[119,727]	-3	hSpCas9	negative selection	4591607
64097981	64098003	20	-	27760321	MV411	viability	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	0.40209819164312444	[411,300]	[211,451]	3	hSpCas9	negative selection	4591608
64098031	64098053	20	-	27760321	MV411	viability	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	-0.02014567974882186	[462,420]	[352,188]	0	hSpCas9	negative selection	4591609
64098101	64098123	20	-	27760321	MV411	viability	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.4170922837374317	[429,336]	[162,594]	3	hSpCas9	negative selection	4591610
64092818	64092840	20	-	27760321	HL60	viability	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	-0.01700789290364696	[643,547]	[530,424]	0	hSpCas9	negative selection	4675069
64092918	64092940	20	-	27760321	HL60	viability	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	-0.48654880640134834	[794,661]	[354,494]	-5	hSpCas9	negative selection	4675070
64097981	64098003	20	-	27760321	HL60	viability	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	0.98549958577825	[411,300]	[558,583]	9	hSpCas9	negative selection	4675071
64098031	64098053	20	-	27760321	HL60	viability	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	0.2542926834687437	[462,420]	[492,363]	3	hSpCas9	negative selection	4675072
64098101	64098123	20	-	27760321	HL60	viability	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.5186701408897021	[429,336]	[538,346]	6	hSpCas9	negative selection	4675073
64092818	64092840	20	-	27760321	HT1080	viability	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	0.1640929329581019	[547,427]	[129,313]	0	hSpCas9	negative selection	4758532
64092918	64092940	20	-	27760321	HT1080	viability	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	0.31141000701133126	[661,516]	[310,269]	1	hSpCas9	negative selection	4758533
64097981	64098003	20	-	27760321	HT1080	viability	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	0.1854957894650072	[300,234]	[87,157]	0	hSpCas9	negative selection	4758534
64098031	64098053	20	-	27760321	HT1080	viability	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	-0.2573412681146297	[420,328]	[29,228]	-1	hSpCas9	negative selection	4758535
64098101	64098123	20	-	27760321	HT1080	viability	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.5866911949740897	[336,262]	[17,146]	-3	hSpCas9	negative selection	4758536
64092818	64092840	20	-	27760321	HT29	viability after 7 days	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	0.36395726501011294	[547,427]	[810,871,740]	5	hSpCas9	negative selection	4841995
64092918	64092940	20	-	27760321	HT29	viability after 7 days	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	0.37117408853344336	[661,516]	[789,681,1425]	5	hSpCas9	negative selection	4841996
64097981	64098003	20	-	27760321	HT29	viability after 7 days	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	0.6006478971301623	[300,234]	[685,568,340]	8	hSpCas9	negative selection	4841997
64098031	64098053	20	-	27760321	HT29	viability after 7 days	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	0.3329708483183871	[420,328]	[505,510,783]	5	hSpCas9	negative selection	4841998
64098101	64098123	20	-	27760321	HT29	viability after 7 days	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.19631572595850502	[336,262]	[421,447,451]	3	hSpCas9	negative selection	4841999
64092818	64092840	20	-	27760321	HT29	viability after 25 days	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	0.3769280869940239	[547,427]	[749,850,550]	4	hSpCas9	negative selection	4925458
64092918	64092940	20	-	27760321	HT29	viability after 25 days	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	0.4298445972510603	[661,516]	[844,724,1183]	4	hSpCas9	negative selection	4925459
64097981	64098003	20	-	27760321	HT29	viability after 25 days	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	0.2871776943543419	[300,234]	[358,324,444]	3	hSpCas9	negative selection	4925460
64098031	64098053	20	-	27760321	HT29	viability after 25 days	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	0.8025436661807029	[420,328]	[497,866,908]	8	hSpCas9	negative selection	4925461
64098101	64098123	20	-	27760321	HT29	viability after 25 days	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.10199089017902255	[336,262]	[220,407,496]	1	hSpCas9	negative selection	4925462
64092818	64092840	20	-	27760321	HT29	viability after 22 days	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	0.3885206464616201	[547,427]	[797,778,635]	4	hSpCas9	negative selection	5008921
64092918	64092940	20	-	27760321	HT29	viability after 22 days	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	0.2738715836135712	[661,516]	[646,975,853]	3	hSpCas9	negative selection	5008922
64097981	64098003	20	-	27760321	HT29	viability after 22 days	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	0.7261491469677521	[300,234]	[412,534,592]	7	hSpCas9	negative selection	5008923
64098031	64098053	20	-	27760321	HT29	viability after 22 days	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	0.8404661582539669	[420,328]	[811,739,775]	8	hSpCas9	negative selection	5008924
64098101	64098123	20	-	27760321	HT29	viability after 22 days	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.6590413481049953	[336,262]	[605,308,727]	7	hSpCas9	negative selection	5008925
64092818	64092840	20	-	27760321	HT29	viability after 19 days	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	0.36258868393071153	[547,427]	[964,595,620]	3	hSpCas9	negative selection	5092384
64092918	64092940	20	-	27760321	HT29	viability after 19 days	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	0.6299922045782149	[661,516]	[836,1176,1091]	6	hSpCas9	negative selection	5092385
64097981	64098003	20	-	27760321	HT29	viability after 19 days	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	0.7142894251291968	[300,234]	[588,630,304]	7	hSpCas9	negative selection	5092386
64098031	64098053	20	-	27760321	HT29	viability after 19 days	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	0.4112741330886405	[420,328]	[863,560,325]	4	hSpCas9	negative selection	5092387
64098101	64098123	20	-	27760321	HT29	viability after 19 days	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.3439806652427123	[336,262]	[419,407,474]	3	hSpCas9	negative selection	5092388
64092818	64092840	20	-	27760321	HT29	viability after 16 days	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	0.3832178107160443	[547,427]	[577,580,967]	4	hSpCas9	negative selection	5175847
64092918	64092940	20	-	27760321	HT29	viability after 16 days	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	0.38400809158773574	[661,516]	[905,831,848]	4	hSpCas9	negative selection	5175848
64097981	64098003	20	-	27760321	HT29	viability after 16 days	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	1.0416511037552416	[300,234]	[652,465,739]	9	hSpCas9	negative selection	5175849
64098031	64098053	20	-	27760321	HT29	viability after 16 days	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	0.4012485016717881	[420,328]	[724,493,460]	4	hSpCas9	negative selection	5175850
64098101	64098123	20	-	27760321	HT29	viability after 16 days	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.6089505965985849	[336,262]	[556,200,789]	7	hSpCas9	negative selection	5175851
64092818	64092840	20	-	27760321	HT29	viability after 13 days	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	0.15994174667753702	[547,427]	[737,641,523]	2	hSpCas9	negative selection	5259310
64092918	64092940	20	-	27760321	HT29	viability after 13 days	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	0.41494150226970783	[661,516]	[862,1038,837]	5	hSpCas9	negative selection	5259311
64097981	64098003	20	-	27760321	HT29	viability after 13 days	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	0.3072302631311632	[300,234]	[343,371,434]	4	hSpCas9	negative selection	5259312
64098031	64098053	20	-	27760321	HT29	viability after 13 days	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	0.21437898003747985	[420,328]	[392,471,640]	2	hSpCas9	negative selection	5259313
64098101	64098123	20	-	27760321	HT29	viability after 13 days	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.47211786993436344	[336,262]	[225,674,543]	6	hSpCas9	negative selection	5259314
64092818	64092840	20	-	27760321	HT29	viability after 10 days	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	0.3091572734865903	[547,427]	[901,574,781]	4	hSpCas9	negative selection	5342773
64092918	64092940	20	-	27760321	HT29	viability after 10 days	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	0.0324013996647855	[661,516]	[783,714,757]	0	hSpCas9	negative selection	5342774
64097981	64098003	20	-	27760321	HT29	viability after 10 days	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	0.7596289565441067	[300,234]	[627,488,579]	9	hSpCas9	negative selection	5342775
64098031	64098053	20	-	27760321	HT29	viability after 10 days	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	0.6680208355647501	[420,328]	[912,510,799]	8	hSpCas9	negative selection	5342776
64098101	64098123	20	-	27760321	HT29	viability after 10 days	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.3439560518243191	[336,262]	[442,546,438]	4	hSpCas9	negative selection	5342777
64092818	64092840	20	-	27760321	MOLM13	viability	GCATTGAGCAGCAGATGCGGGG	OPRL1	ENSG00000125510	-0.6592843619904624	[643,547]	[316,122]	-4	hSpCas9	negative selection	5426236
64092918	64092940	20	-	27760321	MOLM13	viability	CATGACAAGGCAGTTCCCCAGG	OPRL1	ENSG00000125510	0.8243731895683338	[794,661]	[559,864]	6	hSpCas9	negative selection	5426237
64097981	64098003	20	-	27760321	MOLM13	viability	CTCATGGCAGTTAGGGTGAAGG	OPRL1	ENSG00000125510	1.0892313167767733	[411,300]	[512,347]	7	hSpCas9	negative selection	5426238
64098031	64098053	20	-	27760321	MOLM13	viability	GGACGTCGAGGGCACGGATGGG	OPRL1	ENSG00000125510	-0.4377004435748157	[462,420]	[109,246]	-3	hSpCas9	negative selection	5426239
64098101	64098123	20	-	27760321	MOLM13	viability	ACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.6975789128121069	[429,336]	[340,354]	5	hSpCas9	negative selection	5426240
64080253	64080276	20	+	27661255	K562	viability	GTGTGGGACTTCCACGACAGTGG	OPRL1	ENSG00000125510	-0.05559277133508145	[1375,1423]	[1164,998]	-2	dCas9-KRAB	negative selection	5498487
64080367	64080390	20	-	27661255	K562	viability	GGCTCACGGAGGCGAGGGGTGGG	OPRL1	ENSG00000125510	-1.1159917052946104	[140,158]	[79,33]	-8	dCas9-KRAB	negative selection	5498488
64091976	64091999	20	-	27661255	K562	viability	GACGCAGCAGCCGAGTGAGCCGG	OPRL1	ENSG00000125510	0.24050220879051076	[1311,1396]	[1353,1210]	7	dCas9-KRAB	negative selection	5498489
64092044	64092067	20	-	27661255	K562	viability	GCCGGCTGGCAGTCGAGCACAGG	OPRL1	ENSG00000125510	0.21649171443721582	[449,573]	[511,439]	7	dCas9-KRAB	negative selection	5498490
64092401	64092424	20	-	27661255	K562	viability	GGTTTAGAGACTCACACACAGGG	OPRL1	ENSG00000125510	0.09856339743535392	[2060,2314]	[2077,1687]	3	dCas9-KRAB	negative selection	5498491
64098785	64098808	20	-	27260156	BXPC3	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.4528989848944365	[651]	[854,1061,863,945]	8	hSpCas9	negative selection	5559562
64098101	64098124	20	-	27260156	BXPC3	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.3739826677621867	[269]	[257,203,190,211]	-7	hSpCas9	negative selection	5559563
64098042	64098065	20	-	27260156	BXPC3	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.06824966450740094	[550]	[549,611,418,614]	-1	hSpCas9	negative selection	5559564
64092932	64092955	20	+	27260156	BXPC3	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.46066072419521853	[316]	[208,226,288,241]	-7	hSpCas9	negative selection	5623817
64098559	64098582	20	+	27260156	BXPC3	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.0017019426194715415	[113]	[83,92,113,200]	0	hSpCas9	negative selection	5623818
64092756	64092779	20	+	27260156	BXPC3	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.16592538961207634	[429]	[347,361,416,492]	-4	hSpCas9	negative selection	5623819
64098785	64098808	20	-	27260156	A673	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.35787041389591123	[651]	[1094,964,931,1032]	8	hSpCas9	negative selection	5680813
64098101	64098124	20	-	27260156	A673	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.09644915304255253	[269]	[353,289,376,367]	2	hSpCas9	negative selection	5680814
64098042	64098065	20	-	27260156	A673	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.16881843839786242	[550]	[544,540,650,612]	-4	hSpCas9	negative selection	5680815
64092932	64092955	20	+	27260156	A673	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.31848818937491763	[316]	[375,264,337,246]	-7	hSpCas9	negative selection	5745068
64098559	64098582	20	+	27260156	A673	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.11845938830250091	[113]	[126,194,143,122]	3	hSpCas9	negative selection	5745069
64092756	64092779	20	+	27260156	A673	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.016039039514125566	[429]	[525,568,498,490]	0	hSpCas9	negative selection	5745070
64098785	64098808	20	-	27260156	A375	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.034874679691126564	[651]	[776,959,693,718]	0	hSpCas9	negative selection	5802064
64098101	64098124	20	-	27260156	A375	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.6869082324495939	[269]	[227,226,169,165]	-7	hSpCas9	negative selection	5802065
64098042	64098065	20	-	27260156	A375	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.002206958774896184	[550]	[895,656,591,456]	0	hSpCas9	negative selection	5802066
64092932	64092955	20	+	27260156	A375	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.5004177554239309	[316]	[307,264,223,250]	-6	hSpCas9	negative selection	5866319
64098559	64098582	20	+	27260156	A375	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.21488700743051847	[113]	[45,115,170,123]	-3	hSpCas9	negative selection	5866320
64092756	64092779	20	+	27260156	A375	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.4270784125251189	[429]	[786,634,719,564]	6	hSpCas9	negative selection	5866321
64098785	64098808	20	-	27260156	COLO741	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.13928564524525056	[651]	[858,876,1002]	3	hSpCas9	negative selection	5923315
64098101	64098124	20	-	27260156	COLO741	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.12939834341581913	[269]	[338,438,351]	2	hSpCas9	negative selection	5923316
64098042	64098065	20	-	27260156	COLO741	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.059124734426818065	[550]	[925,605,525]	-1	hSpCas9	negative selection	5923317
64092932	64092955	20	+	27260156	COLO741	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.27448967320581397	[316]	[212,337,434]	-5	hSpCas9	negative selection	5987570
64098559	64098582	20	+	27260156	COLO741	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.4624908384472275	[113]	[86,89,135]	-7	hSpCas9	negative selection	5987571
64092756	64092779	20	+	27260156	COLO741	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.02677243975430535	[429]	[687,484,461]	0	hSpCas9	negative selection	5987572
64098785	64098808	20	-	27260156	CAL120	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.37602156821815036	[651]	[1436,998,784]	5	hSpCas9	negative selection	6044566
64098101	64098124	20	-	27260156	CAL120	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.32232522427234506	[269]	[721,356,229]	5	hSpCas9	negative selection	6044567
64098042	64098065	20	-	27260156	CAL120	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.09432819134775375	[550]	[828,802,580]	1	hSpCas9	negative selection	6044568
64092932	64092955	20	+	27260156	CAL120	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.06718379829931309	[316]	[335,560,228]	-1	hSpCas9	negative selection	6108821
64098559	64098582	20	+	27260156	CAL120	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.2174105760836582	[113]	[173,143,56]	-3	hSpCas9	negative selection	6108822
64092756	64092779	20	+	27260156	CAL120	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.23160219461694978	[429]	[518,484,373]	-3	hSpCas9	negative selection	6108823
64098785	64098808	20	-	27260156	CADOES1	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.37342296331381286	[651]	[933,640,716,851]	6	hSpCas9	negative selection	6165817
64098101	64098124	20	-	27260156	CADOES1	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.04659774474995737	[269]	[166,293,284,292]	0	hSpCas9	negative selection	6165818
64098042	64098065	20	-	27260156	CADOES1	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.22946585567902092	[550]	[738,765,508,380]	4	hSpCas9	negative selection	6165819
64092932	64092955	20	+	27260156	CADOES1	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.49577449377138283	[316]	[185,250,253,142]	-7	hSpCas9	negative selection	6230072
64098559	64098582	20	+	27260156	CADOES1	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.7777914101941077	[113]	[57,44,90,52]	-8	hSpCas9	negative selection	6230073
64092756	64092779	20	+	27260156	CADOES1	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.024888215094538674	[429]	[345,436,384,404]	0	hSpCas9	negative selection	6230074
64098785	64098808	20	-	27260156	EWS502	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.417326536321051	[651]	[790,787,980,1164]	7	hSpCas9	negative selection	6287068
64098101	64098124	20	-	27260156	EWS502	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.02464938522607041	[269]	[311,215,181,420]	0	hSpCas9	negative selection	6287069
64098042	64098065	20	-	27260156	EWS502	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.0016650724950272588	[550]	[551,551,556,685]	0	hSpCas9	negative selection	6287070
64092932	64092955	20	+	27260156	EWS502	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.32503978357283625	[316]	[193,209,338,345]	-5	hSpCas9	negative selection	6351323
64098559	64098582	20	+	27260156	EWS502	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.54646745543753	[113]	[181,110,214,200]	8	hSpCas9	negative selection	6351324
64092756	64092779	20	+	27260156	EWS502	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.22403419313563985	[429]	[256,416,445,458]	-4	hSpCas9	negative selection	6351325
64098785	64098808	20	-	27260156	EW8	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.6052719191030052	[651]	[764,864,689,907]	9	hSpCas9	negative selection	6408319
64098101	64098124	20	-	27260156	EW8	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.3317754630435289	[269]	[269,291,258,281]	6	hSpCas9	negative selection	6408320
64098042	64098065	20	-	27260156	EW8	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.14226610815247018	[550]	[627,352,368,297]	-3	hSpCas9	negative selection	6408321
64092932	64092955	20	+	27260156	EW8	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.5418201105595568	[316]	[160,195,120,234]	-7	hSpCas9	negative selection	6472574
64098559	64098582	20	+	27260156	EW8	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.2243462994799268	[113]	[95,97,73,50]	-4	hSpCas9	negative selection	6472575
64092756	64092779	20	+	27260156	EW8	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.14943276038313516	[429]	[322,395,286,255]	-3	hSpCas9	negative selection	6472576
64098785	64098808	20	-	27260156	CORL105	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.16973313589698402	[651]	[667,826,1144,832]	3	hSpCas9	negative selection	6529570
64098101	64098124	20	-	27260156	CORL105	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.06209847140955116	[269]	[287,211,360,463]	1	hSpCas9	negative selection	6529571
64098042	64098065	20	-	27260156	CORL105	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.27879068177805666	[550]	[538,436,741,443]	-5	hSpCas9	negative selection	6529572
64092932	64092955	20	+	27260156	CORL105	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.3963354377951338	[316]	[148,291,303,380]	-6	hSpCas9	negative selection	6593825
64098559	64098582	20	+	27260156	CORL105	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.2651624075136487	[113]	[133,147,124,227]	5	hSpCas9	negative selection	6593826
64092756	64092779	20	+	27260156	CORL105	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.11934261002602363	[429]	[645,354,647,560]	2	hSpCas9	negative selection	6593827
64098785	64098808	20	-	27260156	HS294T	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.6128576737113824	[651]	[384,436,326,390]	7	hSpCas9	negative selection	6650821
64098101	64098124	20	-	27260156	HS294T	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.3564608987341755	[269]	[52,83,72,125]	-5	hSpCas9	negative selection	6650822
64098042	64098065	20	-	27260156	HS294T	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.0680721178640473	[550]	[128,331,218,216]	0	hSpCas9	negative selection	6650823
64092932	64092955	20	+	27260156	HS294T	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.6618194709281835	[316]	[75,58,94,80]	-7	hSpCas9	negative selection	6715076
64098559	64098582	20	+	27260156	HS294T	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.2913240530171166	[113]	[58,51,70,28]	4	hSpCas9	negative selection	6715077
64092756	64092779	20	+	27260156	HS294T	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.22089839163717792	[429]	[135,176,101,156]	-3	hSpCas9	negative selection	6715078
64098785	64098808	20	-	27260156	HCC44	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.2967916667983458	[651]	[699,926,1246,782]	5	hSpCas9	negative selection	6772072
64098101	64098124	20	-	27260156	HCC44	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.8561106763588275	[269]	[253,109,188,140]	-8	hSpCas9	negative selection	6772073
64098042	64098065	20	-	27260156	HCC44	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.10720306670234198	[550]	[498,654,508,614]	-2	hSpCas9	negative selection	6772074
64092932	64092955	20	+	27260156	HCC44	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.6225062608428262	[316]	[125,320,285,184]	-7	hSpCas9	negative selection	6836327
64098559	64098582	20	+	27260156	HCC44	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.4071122232207358	[113]	[178,53,28,126]	-6	hSpCas9	negative selection	6836328
64092756	64092779	20	+	27260156	HCC44	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.042579978429705956	[429]	[453,453,621,492]	0	hSpCas9	negative selection	6836329
64098785	64098808	20	-	27260156	G402	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.27122989485369875	[651]	[1762,996,576,633]	3	hSpCas9	negative selection	6893323
64098101	64098124	20	-	27260156	G402	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.5948250008425764	[269]	[442,175,154,131]	-6	hSpCas9	negative selection	6893324
64098042	64098065	20	-	27260156	G402	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.08370079549407641	[550]	[787,656,653,467]	-1	hSpCas9	negative selection	6893325
64092932	64092955	20	+	27260156	G402	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.1795172911651468	[316]	[499,630,25,251]	-2	hSpCas9	negative selection	6957578
64098559	64098582	20	+	27260156	G402	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.33670487365285884	[113]	[22,242,223,192]	4	hSpCas9	negative selection	6957579
64092756	64092779	20	+	27260156	G402	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.2640695716941035	[429]	[1179,633,481,316]	3	hSpCas9	negative selection	6957580
64098785	64098808	20	-	27260156	L33	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.2786055774060736	[651]	[690,376,414,892]	6	hSpCas9	negative selection	7014574
64098101	64098124	20	-	27260156	L33	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.07352155731001586	[269]	[303,132,180,219]	1	hSpCas9	negative selection	7014575
64098042	64098065	20	-	27260156	L33	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.3421967772111848	[550]	[385,192,283,430]	-7	hSpCas9	negative selection	7014576
64092932	64092955	20	+	27260156	L33	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.4234196786642668	[316]	[297,73,175,185]	-7	hSpCas9	negative selection	7078829
64098559	64098582	20	+	27260156	L33	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.15746604439933387	[113]	[92,34,64,126]	-4	hSpCas9	negative selection	7078830
64092756	64092779	20	+	27260156	L33	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.15231038886568585	[429]	[427,150,252,347]	-3	hSpCas9	negative selection	7078831
64098785	64098808	20	-	27260156	K562	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.23978151104892542	[651]	[932,492,796,534]	3	hSpCas9	negative selection	7135825
64098101	64098124	20	-	27260156	K562	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.5827085626191223	[269]	[208,691,451,114]	7	hSpCas9	negative selection	7135826
64098042	64098065	20	-	27260156	K562	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.02606499387550351	[550]	[567,586,555,310]	0	hSpCas9	negative selection	7135827
64092932	64092955	20	+	27260156	K562	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.5896956971555762	[316]	[327,178,157,102]	-6	hSpCas9	negative selection	7200080
64098559	64098582	20	+	27260156	K562	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.2625137887190405	[113]	[52,162,63,192]	3	hSpCas9	negative selection	7200081
64092756	64092779	20	+	27260156	K562	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.067509337894123	[429]	[510,475,112,371]	-1	hSpCas9	negative selection	7200082
64098785	64098808	20	-	27260156	HT29	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.2381570268048483	[651]	[856,1012,1015,856]	4	hSpCas9	negative selection	7257076
64098101	64098124	20	-	27260156	HT29	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.16797997782875196	[269]	[271,305,384,212]	-3	hSpCas9	negative selection	7257077
64098042	64098065	20	-	27260156	HT29	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.2209161055418096	[550]	[611,547,782,376]	-4	hSpCas9	negative selection	7257078
64092932	64092955	20	+	27260156	HT29	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.38188990150863444	[316]	[330,374,239,249]	-6	hSpCas9	negative selection	7321331
64098559	64098582	20	+	27260156	HT29	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.017565251947766924	[113]	[166,181,78,137]	0	hSpCas9	negative selection	7321332
64092756	64092779	20	+	27260156	HT29	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.06733050594757037	[429]	[546,570,422,464]	-1	hSpCas9	negative selection	7321333
64098785	64098808	20	-	27260156	MHHES1	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.031980854597462915	[651]	[747,924,821,554]	0	hSpCas9	negative selection	7378327
64098101	64098124	20	-	27260156	MHHES1	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.04259415415975065	[269]	[489,360,149,277]	0	hSpCas9	negative selection	7378328
64098042	64098065	20	-	27260156	MHHES1	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.03966310328169498	[550]	[505,678,649,569]	0	hSpCas9	negative selection	7378329
64092932	64092955	20	+	27260156	MHHES1	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	0.13860344853615048	[316]	[427,578,403,216]	2	hSpCas9	negative selection	7442582
64098559	64098582	20	+	27260156	MHHES1	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.02599978331467323	[113]	[118,157,208,53]	0	hSpCas9	negative selection	7442583
64092756	64092779	20	+	27260156	MHHES1	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.18575023922607434	[429]	[413,370,467,431]	-4	hSpCas9	negative selection	7442584
64098785	64098808	20	-	27260156	MEWO	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.3640822791075875	[651]	[884,672,816]	7	hSpCas9	negative selection	7499578
64098101	64098124	20	-	27260156	MEWO	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.21449995683506184	[269]	[348,302,237]	5	hSpCas9	negative selection	7499579
64098042	64098065	20	-	27260156	MEWO	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.44419549912388484	[550]	[317,332,473]	-7	hSpCas9	negative selection	7499580
64092932	64092955	20	+	27260156	MEWO	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.31722221634857606	[316]	[260,134,322]	-6	hSpCas9	negative selection	7563833
64098559	64098582	20	+	27260156	MEWO	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.16656870958100933	[113]	[160,60,75]	-4	hSpCas9	negative selection	7563834
64092756	64092779	20	+	27260156	MEWO	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.027264559246778175	[429]	[483,440,318]	0	hSpCas9	negative selection	7563835
64098785	64098808	20	-	27260156	LNCAPCLONEFGC	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.36553341643691595	[651]	[616,644,1079,758]	6	hSpCas9	negative selection	7620829
64098101	64098124	20	-	27260156	LNCAPCLONEFGC	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.3067108777298905	[269]	[284,283,366,284]	5	hSpCas9	negative selection	7620830
64098042	64098065	20	-	27260156	LNCAPCLONEFGC	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.009830037617450882	[550]	[581,564,425,392]	0	hSpCas9	negative selection	7620831
64092932	64092955	20	+	27260156	LNCAPCLONEFGC	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.8417687979181807	[316]	[195,141,191,115]	-8	hSpCas9	negative selection	7685084
64098559	64098582	20	+	27260156	LNCAPCLONEFGC	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.3317951859188275	[113]	[158,127,167,69]	5	hSpCas9	negative selection	7685085
64092756	64092779	20	+	27260156	LNCAPCLONEFGC	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.12225779006323631	[429]	[372,246,382,438]	-2	hSpCas9	negative selection	7685086
64098785	64098808	20	-	27260156	PANC0327	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	-0.12444430296790021	[651]	[495,509,570,547]	-2	hSpCas9	negative selection	7742080
64098101	64098124	20	-	27260156	PANC0327	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.8455305068369352	[269]	[107,123,146,153]	-8	hSpCas9	negative selection	7742081
64098042	64098065	20	-	27260156	PANC0327	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.030713064469025636	[550]	[522,321,689,489]	0	hSpCas9	negative selection	7742082
64092932	64092955	20	+	27260156	PANC0327	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.6757565302634758	[316]	[182,150,234,139]	-7	hSpCas9	negative selection	7806335
64098559	64098582	20	+	27260156	PANC0327	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.11493258832523257	[113]	[171,29,109,141]	1	hSpCas9	negative selection	7806336
64092756	64092779	20	+	27260156	PANC0327	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.27085512279054713	[429]	[304,185,288,501]	-4	hSpCas9	negative selection	7806337
64098785	64098808	20	-	27260156	NCIH2009	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.44173133049454816	[651]	[1365,1301,1065]	6	hSpCas9	negative selection	7863331
64098101	64098124	20	-	27260156	NCIH2009	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.0727218665048287	[269]	[504,447,256]	1	hSpCas9	negative selection	7863332
64098042	64098065	20	-	27260156	NCIH2009	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.2472794114979651	[550]	[1246,561,1002]	3	hSpCas9	negative selection	7863333
64092932	64092955	20	+	27260156	NCIH2009	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.39662034140833113	[316]	[320,319,364]	-5	hSpCas9	negative selection	7927586
64098559	64098582	20	+	27260156	NCIH2009	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.19515115000612537	[113]	[141,177,96]	-3	hSpCas9	negative selection	7927587
64092756	64092779	20	+	27260156	NCIH2009	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.1743083976577639	[429]	[553,685,767]	2	hSpCas9	negative selection	7927588
64098785	64098808	20	-	27260156	NCIH1373	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.3812726135447103	[651]	[1519,698,846,222]	4	hSpCas9	negative selection	7984582
64098101	64098124	20	-	27260156	NCIH1373	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.19753694401504496	[269]	[443,280,193,131]	2	hSpCas9	negative selection	7984583
64098042	64098065	20	-	27260156	NCIH1373	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.3592832423981256	[550]	[1322,500,606,224]	3	hSpCas9	negative selection	7984584
64092932	64092955	20	+	27260156	NCIH1373	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.2627109845237333	[316]	[140,270,473,70]	-3	hSpCas9	negative selection	8048837
64098559	64098582	20	+	27260156	NCIH1373	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.3004598556736049	[113]	[165,162,84,57]	3	hSpCas9	negative selection	8048838
64092756	64092779	20	+	27260156	NCIH1373	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.21715869726693748	[429]	[810,538,366,148]	2	hSpCas9	negative selection	8048839
64098785	64098808	20	-	27260156	PATU8902	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.8378394404316181	[651]	[1494,1149,2297,1324]	8	hSpCas9	negative selection	8105833
64098101	64098124	20	-	27260156	PATU8902	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.4228857561338075	[269]	[322,413,206,182]	-4	hSpCas9	negative selection	8105834
64098042	64098065	20	-	27260156	PATU8902	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.5132224319940498	[550]	[1764,1204,464,1091]	5	hSpCas9	negative selection	8105835
64092932	64092955	20	+	27260156	PATU8902	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.507288228068373	[316]	[391,463,131,295]	-5	hSpCas9	negative selection	8170088
64098559	64098582	20	+	27260156	PATU8902	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-1.1237351078465307	[113]	[21,140,103,8]	-7	hSpCas9	negative selection	8170089
64092756	64092779	20	+	27260156	PATU8902	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.1315043200557919	[429]	[742,724,520,664]	1	hSpCas9	negative selection	8170090
64098785	64098808	20	-	27260156	PANC1	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.2610813440102916	[651]	[662,966,727,418]	4	hSpCas9	negative selection	8227084
64098101	64098124	20	-	27260156	PANC1	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.07722952150568396	[269]	[219,305,201,172]	-1	hSpCas9	negative selection	8227085
64098042	64098065	20	-	27260156	PANC1	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.08714239503858104	[550]	[527,782,505,279]	1	hSpCas9	negative selection	8227086
64092932	64092955	20	+	27260156	PANC1	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.07273790074229947	[316]	[367,228,166,257]	-1	hSpCas9	negative selection	8291339
64098559	64098582	20	+	27260156	PANC1	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.062294127870194727	[113]	[58,82,135,122]	0	hSpCas9	negative selection	8291340
64092756	64092779	20	+	27260156	PANC1	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.0013354846248075647	[429]	[349,523,402,245]	0	hSpCas9	negative selection	8291341
64098785	64098808	20	-	27260156	PANC0813	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.540129624883174	[651]	[1144,1153,1140,1020]	8	hSpCas9	negative selection	8348335
64098101	64098124	20	-	27260156	PANC0813	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.40480070551567193	[269]	[571,257,389,469]	6	hSpCas9	negative selection	8348336
64098042	64098065	20	-	27260156	PANC0813	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.19435380808949312	[550]	[647,593,550,480]	-3	hSpCas9	negative selection	8348337
64092932	64092955	20	+	27260156	PANC0813	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.2952656386036102	[316]	[232,343,328,300]	-5	hSpCas9	negative selection	8412590
64098559	64098582	20	+	27260156	PANC0813	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.055743780375989704	[113]	[92,194,156,108]	0	hSpCas9	negative selection	8412591
64092756	64092779	20	+	27260156	PANC0813	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.3484372987747214	[429]	[295,420,476,383]	-5	hSpCas9	negative selection	8412592
64098785	64098808	20	-	27260156	RDES	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.22501900254259177	[651]	[758,771,1009,995]	3	hSpCas9	negative selection	8469586
64098101	64098124	20	-	27260156	RDES	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.09373913202154849	[269]	[242,271,274,391]	-1	hSpCas9	negative selection	8469587
64098042	64098065	20	-	27260156	RDES	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.16749769052823163	[550]	[572,652,793,867]	2	hSpCas9	negative selection	8469588
64092932	64092955	20	+	27260156	RDES	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.6069006408030699	[316]	[165,205,258,357]	-8	hSpCas9	negative selection	8533841
64098559	64098582	20	+	27260156	RDES	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.09790012369398027	[113]	[135,136,157,124]	1	hSpCas9	negative selection	8533842
64092756	64092779	20	+	27260156	RDES	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.3023257064215631	[429]	[345,383,496,377]	-5	hSpCas9	negative selection	8533843
64098785	64098808	20	-	27260156	PC3	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.1351478051698538	[651]	[539,609,936,860]	3	hSpCas9	negative selection	8590837
64098101	64098124	20	-	27260156	PC3	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.20996485642847806	[269]	[209,167,505,464]	4	hSpCas9	negative selection	8590838
64098042	64098065	20	-	27260156	PC3	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.10321954243668435	[550]	[299,479,996,504]	-2	hSpCas9	negative selection	8590839
64092932	64092955	20	+	27260156	PC3	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.6474694182300933	[316]	[140,154,358,221]	-9	hSpCas9	negative selection	8655092
64098559	64098582	20	+	27260156	PC3	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.23147067202617677	[113]	[61,209,129,146]	5	hSpCas9	negative selection	8655093
64092756	64092779	20	+	27260156	PC3	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.19558737315342675	[429]	[196,419,618,400]	-4	hSpCas9	negative selection	8655094
64098785	64098808	20	-	27260156	PATU8988T	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.5282185954360075	[651]	[629,1212,1063,739]	8	hSpCas9	negative selection	8712088
64098101	64098124	20	-	27260156	PATU8988T	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.05143928832413103	[269]	[341,280,175,285]	0	hSpCas9	negative selection	8712089
64098042	64098065	20	-	27260156	PATU8988T	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.04843515140587726	[550]	[536,443,647,562]	0	hSpCas9	negative selection	8712090
64092932	64092955	20	+	27260156	PATU8988T	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-1.1345216700943699	[316]	[130,95,150,178]	-9	hSpCas9	negative selection	8776343
64098559	64098582	20	+	27260156	PATU8988T	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.3294910227814718	[113]	[212,121,78,138]	5	hSpCas9	negative selection	8776344
64092756	64092779	20	+	27260156	PATU8988T	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.08753949694964977	[429]	[291,489,486,505]	1	hSpCas9	negative selection	8776345
64098785	64098808	20	-	27260156	T47D	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.1317278593375626	[651]	[779,732,875,950]	2	hSpCas9	negative selection	8833339
64098101	64098124	20	-	27260156	T47D	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.39825936450830035	[269]	[224,243,224,260]	-7	hSpCas9	negative selection	8833340
64098042	64098065	20	-	27260156	T47D	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.10735432012751171	[550]	[594,589,555,644]	-2	hSpCas9	negative selection	8833341
64092932	64092955	20	+	27260156	T47D	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.29188575072926826	[316]	[359,272,288,286]	-6	hSpCas9	negative selection	8897594
64098559	64098582	20	+	27260156	T47D	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.30061143917545197	[113]	[91,124,99,112]	-6	hSpCas9	negative selection	8897595
64092756	64092779	20	+	27260156	T47D	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.16610532076147597	[429]	[497,307,471,521]	-4	hSpCas9	negative selection	8897596
64098785	64098808	20	-	27260156	SU8686	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.48565136218511973	[651]	[926,871,871,950]	7	hSpCas9	negative selection	8954590
64098101	64098124	20	-	27260156	SU8686	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.06066539272597615	[269]	[240,233,215,352]	-1	hSpCas9	negative selection	8954591
64098042	64098065	20	-	27260156	SU8686	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.18728373554665648	[550]	[397,357,519,701]	-3	hSpCas9	negative selection	8954592
64092932	64092955	20	+	27260156	SU8686	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.5937589923770463	[316]	[152,120,294,296]	-7	hSpCas9	negative selection	9018845
64098559	64098582	20	+	27260156	SU8686	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.08908939931788362	[113]	[116,136,113,107]	1	hSpCas9	negative selection	9018846
64092756	64092779	20	+	27260156	SU8686	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	0.09933543912438964	[429]	[464,386,489,496]	1	hSpCas9	negative selection	9018847
64098785	64098808	20	-	27260156	SKES1	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.36825309343098245	[651]	[1096,936,747,639]	7	hSpCas9	negative selection	9075841
64098101	64098124	20	-	27260156	SKES1	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.04870135279334664	[269]	[265,369,280,148]	-1	hSpCas9	negative selection	9075842
64098042	64098065	20	-	27260156	SKES1	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.061738524659488564	[550]	[623,716,369,438]	-1	hSpCas9	negative selection	9075843
64092932	64092955	20	+	27260156	SKES1	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.30471673756258033	[316]	[170,371,277,207]	-6	hSpCas9	negative selection	9140096
64098559	64098582	20	+	27260156	SKES1	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.06674997295875729	[113]	[186,100,96,99]	1	hSpCas9	negative selection	9140097
64092756	64092779	20	+	27260156	SKES1	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.16736931243714945	[429]	[353,372,321,460]	-4	hSpCas9	negative selection	9140098
64098785	64098808	20	-	27260156	TOV112D	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.30698140553197095	[651]	[963,1031,625,679]	6	hSpCas9	negative selection	9197092
64098101	64098124	20	-	27260156	TOV112D	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.28098191257332505	[269]	[177,244,294,174]	-5	hSpCas9	negative selection	9197093
64098042	64098065	20	-	27260156	TOV112D	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.43422284624184926	[550]	[603,351,321,358]	-7	hSpCas9	negative selection	9197094
64092932	64092955	20	+	27260156	TOV112D	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.39695850998024207	[316]	[188,418,245,151]	-7	hSpCas9	negative selection	9261347
64098559	64098582	20	+	27260156	TOV112D	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.22451632590663384	[113]	[136,129,173,92]	4	hSpCas9	negative selection	9261348
64092756	64092779	20	+	27260156	TOV112D	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.1417076974975611	[429]	[420,608,296,292]	-3	hSpCas9	negative selection	9261349
64098785	64098808	20	-	27260156	TC71	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.3587145702042214	[651]	[954,692,863,1083]	8	hSpCas9	negative selection	9318343
64098101	64098124	20	-	27260156	TC71	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	0.03925652323894002	[269]	[258,311,327,289]	1	hSpCas9	negative selection	9318344
64098042	64098065	20	-	27260156	TC71	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	-0.2739494796702684	[550]	[496,320,628,502]	-6	hSpCas9	negative selection	9318345
64092932	64092955	20	+	27260156	TC71	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.21958508971978408	[316]	[240,279,277,374]	-5	hSpCas9	negative selection	9382598
64098559	64098582	20	+	27260156	TC71	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	0.23969974356068557	[113]	[152,113,107,206]	6	hSpCas9	negative selection	9382599
64092756	64092779	20	+	27260156	TC71	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.014522381950452523	[429]	[460,390,496,475]	0	hSpCas9	negative selection	9382600
64098785	64098808	20	-	27260156	TC32	viability	ACGCCTAGTCATGCGGGCCGCGG	OPRL1	ENSG00000125510	0.3163838994645717	[651]	[641,607,1103,786]	5	hSpCas9	negative selection	9439594
64098101	64098124	20	-	27260156	TC32	viability	AACGGGAACACCGACAACAGAGG	OPRL1	ENSG00000125510	-0.10439865107699753	[269]	[140,244,357,213]	-2	hSpCas9	negative selection	9439595
64098042	64098065	20	-	27260156	TC32	viability	TGCTGGACGTGCGGACGTCGAGG	OPRL1	ENSG00000125510	0.13236222271260198	[550]	[389,473,714,751]	2	hSpCas9	negative selection	9439596
64092932	64092955	20	+	27260156	TC32	viability	TTGTCATGTACGTCATCCTCAGG	OPRL1	ENSG00000125510	-0.24356402652731424	[316]	[160,261,279,302]	-4	hSpCas9	negative selection	9503849
64098559	64098582	20	+	27260156	TC32	viability	GCCGAGCAGCGAGACTGCCGTGG	OPRL1	ENSG00000125510	-0.6153172402852052	[113]	[33,59,108,88]	-8	hSpCas9	negative selection	9503850
64092756	64092779	20	+	27260156	TC32	viability	TATCTACGGCAGCCACCTTCAGG	OPRL1	ENSG00000125510	-0.24698644037774417	[429]	[286,212,514,417]	-4	hSpCas9	negative selection	9503851
64092737	64092760	20	-	27869803	HPAFII	viability after 27 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.06236588096037332	[103]	[77,30,NaN]	0	hSpCas9	negative selection	9578769
64092742	64092765	20	-	27869803	HPAFII	viability after 27 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.2961309883639909	[1120]	[703,739,NaN]	2	hSpCas9	negative selection	9578770
64092930	64092953	20	-	27869803	HPAFII	viability after 27 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.9871626605237647	[447]	[132,106,NaN]	-6	hSpCas9	negative selection	9578771
64098119	64098142	20	-	27869803	HPAFII	viability after 27 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.4392437970289652	[493]	[208,176,NaN]	-3	hSpCas9	negative selection	9578772
64098525	64098548	20	+	27869803	HPAFII	viability after 27 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	1.095714717883301	[113]	[102,148,NaN]	8	hSpCas9	negative selection	9578773
64098603	64098626	20	-	27869803	HPAFII	viability after 27 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-0.4766144988161142	[236]	[46,124,NaN]	-4	hSpCas9	negative selection	9578774
64092737	64092760	20	-	27869803	HPAFII	viability after 15 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.4468802062897551	[103]	[205,118,NaN]	5	hSpCas9	negative selection	9661218
64092742	64092765	20	-	27869803	HPAFII	viability after 15 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.06186472702284229	[1120]	[1518,1094,NaN]	0	hSpCas9	negative selection	9661219
64092930	64092953	20	-	27869803	HPAFII	viability after 15 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.7611513453482112	[447]	[473,165,NaN]	-7	hSpCas9	negative selection	9661220
64098119	64098142	20	-	27869803	HPAFII	viability after 15 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.42532330960008613	[493]	[485,338,NaN]	-5	hSpCas9	negative selection	9661221
64098525	64098548	20	+	27869803	HPAFII	viability after 15 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.8522257360313146	[113]	[206,229,NaN]	8	hSpCas9	negative selection	9661222
64098603	64098626	20	-	27869803	HPAFII	viability after 15 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-0.04807013391970394	[236]	[217,263,NaN]	0	hSpCas9	negative selection	9661223
64092737	64092760	20	-	27869803	ASPC1	viability after 36 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	1.288462187744478	[246]	[199,91,309]	9	hSpCas9	negative selection	9743667
64092742	64092765	20	-	27869803	ASPC1	viability after 36 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.22437024822864626	[2338]	[630,1238,943]	2	hSpCas9	negative selection	9743668
64092930	64092953	20	-	27869803	ASPC1	viability after 36 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	0.44916795213514005	[992]	[366,768,307]	4	hSpCas9	negative selection	9743669
64098119	64098142	20	-	27869803	ASPC1	viability after 36 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	1.0470717176527709	[1017]	[963,890,440]	8	hSpCas9	negative selection	9743670
64098525	64098548	20	+	27869803	ASPC1	viability after 36 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	-0.18771050008879586	[321]	[201,45,66]	-2	hSpCas9	negative selection	9743671
64098603	64098626	20	-	27869803	ASPC1	viability after 36 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	0.06227170110214324	[672]	[128,387,210]	0	hSpCas9	negative selection	9743672
64092737	64092760	20	-	27869803	PATU8988S	viability after 35 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.8895970332009087	[220]	[66,28,NaN]	-7	hSpCas9	negative selection	9826116
64092742	64092765	20	-	27869803	PATU8988S	viability after 35 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.43681871615650003	[1806]	[1037,931,NaN]	5	hSpCas9	negative selection	9826117
64092930	64092953	20	-	27869803	PATU8988S	viability after 35 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.13704961598696708	[839]	[373,240,NaN]	-1	hSpCas9	negative selection	9826118
64098119	64098142	20	-	27869803	PATU8988S	viability after 35 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	0.35424375355509097	[836]	[615,244,NaN]	4	hSpCas9	negative selection	9826119
64098525	64098548	20	+	27869803	PATU8988S	viability after 35 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.39278812864660384	[361]	[155,226,NaN]	4	hSpCas9	negative selection	9826120
64098603	64098626	20	-	27869803	PATU8988S	viability after 35 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	0.08162053453648213	[496]	[131,291,NaN]	0	hSpCas9	negative selection	9826121
64092737	64092760	20	-	27869803	PATU8988S	viability after 31 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.1445018239725575	[220]	[125,60,NaN]	1	hSpCas9	negative selection	9908565
64092742	64092765	20	-	27869803	PATU8988S	viability after 31 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.34417435947636	[1806]	[999,805,NaN]	4	hSpCas9	negative selection	9908566
64092930	64092953	20	-	27869803	PATU8988S	viability after 31 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.29144264628806477	[839]	[263,285,NaN]	-3	hSpCas9	negative selection	9908567
64098119	64098142	20	-	27869803	PATU8988S	viability after 31 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	0.35820816852150117	[836]	[473,368,NaN]	4	hSpCas9	negative selection	9908568
64098525	64098548	20	+	27869803	PATU8988S	viability after 31 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.29804768527889947	[361]	[125,242,NaN]	3	hSpCas9	negative selection	9908569
64098603	64098626	20	-	27869803	PATU8988S	viability after 31 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-0.1602595728675475	[496]	[80,299,NaN]	-2	hSpCas9	negative selection	9908570
64092737	64092760	20	-	27869803	HPAFII	viability after 35 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.6870762283074062	[103]	[88,79,NaN]	4	hSpCas9	negative selection	9991014
64092742	64092765	20	-	27869803	HPAFII	viability after 35 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.31391114207617576	[1120]	[656,759,NaN]	2	hSpCas9	negative selection	9991015
64092930	64092953	20	-	27869803	HPAFII	viability after 35 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.6976135161774182	[447]	[176,97,NaN]	-4	hSpCas9	negative selection	9991016
64098119	64098142	20	-	27869803	HPAFII	viability after 35 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.33853574705377065	[493]	[106,299,NaN]	-2	hSpCas9	negative selection	9991017
64098525	64098548	20	+	27869803	HPAFII	viability after 35 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	0.710143018875363	[113]	[100,86,NaN]	5	hSpCas9	negative selection	9991018
64098603	64098626	20	-	27869803	HPAFII	viability after 35 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	-0.7561849240724559	[236]	[23,123,NaN]	-4	hSpCas9	negative selection	9991019
64092737	64092760	20	-	27869803	HPAFII	viability after 31 days	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.13566614430258528	[103]	[77,48,NaN]	1	hSpCas9	negative selection	10073463
64092742	64092765	20	-	27869803	HPAFII	viability after 31 days	CCGTAGATAACCTCCCAGAACGG	OPRL1	ENSG00000125510	0.16736097306716102	[1120]	[728,681,NaN]	1	hSpCas9	negative selection	10073464
64092930	64092953	20	-	27869803	HPAFII	viability after 31 days	TGAGGATGACGTACATGACAAGG	OPRL1	ENSG00000125510	-0.9072794412988043	[447]	[179,83,NaN]	-5	hSpCas9	negative selection	10073465
64098119	64098142	20	-	27869803	HPAFII	viability after 31 days	TGCCGAGCCCATGATGGCAACGG	OPRL1	ENSG00000125510	-0.13029276508428134	[493]	[192,318,NaN]	-1	hSpCas9	negative selection	10073466
64098525	64098548	20	+	27869803	HPAFII	viability after 31 days	AGGTCTTCGTGCTGGCCCAAGGG	OPRL1	ENSG00000125510	1.3545731109709196	[113]	[165,160,NaN]	8	hSpCas9	negative selection	10073467
64098603	64098626	20	-	27869803	HPAFII	viability after 31 days	GCAGCTGTTGACGTAGCCCAGGG	OPRL1	ENSG00000125510	0.35583626490966547	[236]	[40,310,NaN]	2	hSpCas9	negative selection	10073468
64092737	64092760	20	-	28162770	P31FUJ	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.979116885692561	[78]	[182]	9	hSpCas9	negative selection	10204927
64097882	64097905	20	-	28162770	P31FUJ	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	0.3521602963067776	[187]	[281]	4	hSpCas9	negative selection	10204928
64092878	64092901	20	-	28162770	P31FUJ	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-0.9958868595444668	[352]	[207]	-6	hSpCas9	negative selection	10204929
64097901	64097924	20	-	28162770	P31FUJ	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	-0.0540963174298566	[272]	[308]	0	hSpCas9	negative selection	10204930
64092768	64092791	20	-	28162770	P31FUJ	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	-0.6313515809046533	[57]	[43]	-5	hSpCas9	negative selection	10204931
64092788	64092811	20	-	28162770	P31FUJ	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	-0.21043439138592412	[63]	[64]	-2	hSpCas9	negative selection	10204932
64097849	64097872	20	-	28162770	P31FUJ	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.47072643018399885	[322]	[525]	5	hSpCas9	negative selection	10204933
64098032	64098055	20	-	28162770	P31FUJ	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	-0.7821407954048136	[119]	[81]	-6	hSpCas9	negative selection	10204934
64098095	64098118	20	-	28162770	P31FUJ	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.35686729898430514	[407]	[613]	4	hSpCas9	negative selection	10204935
64092826	64092849	20	+	28162770	P31FUJ	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.45049821550006997	[240]	[386]	5	hSpCas9	negative selection	10204936
64092737	64092760	20	-	28162770	TF1	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10374293
64097882	64097905	20	-	28162770	TF1	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	NaN	[NaN]	[348]	1	hSpCas9	negative selection	10374294
64092878	64092901	20	-	28162770	TF1	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	NaN	[NaN]	[141]	1	hSpCas9	negative selection	10374295
64097901	64097924	20	-	28162770	TF1	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10374296
64092768	64092791	20	-	28162770	TF1	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10374297
64092788	64092811	20	-	28162770	TF1	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	NaN	[NaN]	[185]	1	hSpCas9	negative selection	10374298
64097849	64097872	20	-	28162770	TF1	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	NaN	[NaN]	[406]	1	hSpCas9	negative selection	10374299
64098032	64098055	20	-	28162770	TF1	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10374300
64098095	64098118	20	-	28162770	TF1	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	NaN	[NaN]	[716]	1	hSpCas9	negative selection	10374301
64092826	64092849	20	+	28162770	TF1	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10374302
64092737	64092760	20	-	28162770	SKM1	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.5589672921882116	[19]	[23]	-4	hSpCas9	negative selection	10543659
64097882	64097905	20	-	28162770	SKM1	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	0.6613205408233129	[48]	[136]	6	hSpCas9	negative selection	10543660
64092878	64092901	20	-	28162770	SKM1	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-1.9000042100232786	[94]	[44]	-8	hSpCas9	negative selection	10543661
64097901	64097924	20	-	28162770	SKM1	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.6634251291482363	[59]	[167]	6	hSpCas9	negative selection	10543662
64092768	64092791	20	-	28162770	SKM1	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	0.4999263968653569	[21]	[54]	5	hSpCas9	negative selection	10543663
64092788	64092811	20	-	28162770	SKM1	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	-0.2537179384474797	[28]	[42]	-2	hSpCas9	negative selection	10543664
64097849	64097872	20	-	28162770	SKM1	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.39244197019895155	[77]	[180]	4	hSpCas9	negative selection	10543665
64098032	64098055	20	-	28162770	SKM1	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	0.5851736834838679	[22]	[60]	5	hSpCas9	negative selection	10543666
64098095	64098118	20	-	28162770	SKM1	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.6904483029147828	[67]	[193]	6	hSpCas9	negative selection	10543667
64092826	64092849	20	+	28162770	SKM1	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.6727629937275726	[54]	[154]	6	hSpCas9	negative selection	10543668
64092737	64092760	20	-	28162770	SKM1	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.5589672921882116	[19]	[23]	-4	hSpCas9	negative selection	10713025
64097882	64097905	20	-	28162770	SKM1	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	0.6613205408233129	[48]	[136]	6	hSpCas9	negative selection	10713026
64092878	64092901	20	-	28162770	SKM1	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-1.9000042100232786	[94]	[44]	-8	hSpCas9	negative selection	10713027
64097901	64097924	20	-	28162770	SKM1	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.6634251291482363	[59]	[167]	6	hSpCas9	negative selection	10713028
64092768	64092791	20	-	28162770	SKM1	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	0.4999263968653569	[21]	[54]	5	hSpCas9	negative selection	10713029
64092788	64092811	20	-	28162770	SKM1	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	-0.2537179384474797	[28]	[42]	-2	hSpCas9	negative selection	10713030
64097849	64097872	20	-	28162770	SKM1	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.39244197019895155	[77]	[180]	4	hSpCas9	negative selection	10713031
64098032	64098055	20	-	28162770	SKM1	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	0.5851736834838679	[22]	[60]	5	hSpCas9	negative selection	10713032
64098095	64098118	20	-	28162770	SKM1	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.6904483029147828	[67]	[193]	6	hSpCas9	negative selection	10713033
64092826	64092849	20	+	28162770	SKM1	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.6727629937275726	[54]	[154]	6	hSpCas9	negative selection	10713034
64092737	64092760	20	-	28162770	PL21	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.4923203659826303	[48]	[29]	4	hSpCas9	negative selection	10882391
64097882	64097905	20	-	28162770	PL21	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	-0.16374379683942064	[156]	[60]	-1	hSpCas9	negative selection	10882392
64092878	64092901	20	-	28162770	PL21	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-0.5644304410714875	[298]	[87]	-4	hSpCas9	negative selection	10882393
64097901	64097924	20	-	28162770	PL21	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.29250363263797985	[241]	[128]	2	hSpCas9	negative selection	10882394
64092768	64092791	20	-	28162770	PL21	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	-2.3359132857508897	[57]	[4]	-8	hSpCas9	negative selection	10882395
64092788	64092811	20	-	28162770	PL21	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	-0.24346703698629457	[67]	[24]	-2	hSpCas9	negative selection	10882396
64097849	64097872	20	-	28162770	PL21	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.464902834239865	[277]	[166]	4	hSpCas9	negative selection	10882397
64098032	64098055	20	-	28162770	PL21	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	-1.6218620835326854	[98]	[13]	-8	hSpCas9	negative selection	10882398
64098095	64098118	20	-	28162770	PL21	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.7634070441111573	[267]	[197]	6	hSpCas9	negative selection	10882399
64092826	64092849	20	+	28162770	PL21	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.8229819988815656	[212]	[163]	7	hSpCas9	negative selection	10882400
64092737	64092760	20	-	28162770	P31FUJ	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.979116885692561	[78]	[182]	9	hSpCas9	negative selection	11051757
64097882	64097905	20	-	28162770	P31FUJ	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	0.3521602963067776	[187]	[281]	4	hSpCas9	negative selection	11051758
64092878	64092901	20	-	28162770	P31FUJ	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-0.9958868595444668	[352]	[207]	-6	hSpCas9	negative selection	11051759
64097901	64097924	20	-	28162770	P31FUJ	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	-0.0540963174298566	[272]	[308]	0	hSpCas9	negative selection	11051760
64092768	64092791	20	-	28162770	P31FUJ	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	-0.6313515809046533	[57]	[43]	-5	hSpCas9	negative selection	11051761
64092788	64092811	20	-	28162770	P31FUJ	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	-0.21043439138592412	[63]	[64]	-2	hSpCas9	negative selection	11051762
64097849	64097872	20	-	28162770	P31FUJ	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.47072643018399885	[322]	[525]	5	hSpCas9	negative selection	11051763
64098032	64098055	20	-	28162770	P31FUJ	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	-0.7821407954048136	[119]	[81]	-6	hSpCas9	negative selection	11051764
64098095	64098118	20	-	28162770	P31FUJ	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.35686729898430514	[407]	[613]	4	hSpCas9	negative selection	11051765
64092826	64092849	20	+	28162770	P31FUJ	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.45049821550006997	[240]	[386]	5	hSpCas9	negative selection	11051766
64092737	64092760	20	-	28162770	OCIAML5	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.3585004150756612	[34]	[80]	3	hSpCas9	negative selection	11221123
64097882	64097905	20	-	28162770	OCIAML5	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	0.8126231223278934	[87]	[278]	7	hSpCas9	negative selection	11221124
64092878	64092901	20	-	28162770	OCIAML5	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-0.2898241466429243	[127]	[188]	-2	hSpCas9	negative selection	11221125
64097901	64097924	20	-	28162770	OCIAML5	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.5132838043144938	[143]	[370]	4	hSpCas9	negative selection	11221126
64092768	64092791	20	-	28162770	OCIAML5	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	-1.460875813539521	[60]	[39]	-7	hSpCas9	negative selection	11221127
64092788	64092811	20	-	28162770	OCIAML5	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	0.281199959999467	[61]	[135]	2	hSpCas9	negative selection	11221128
64097849	64097872	20	-	28162770	OCIAML5	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	-0.4328412746217196	[257]	[344]	-3	hSpCas9	negative selection	11221129
64098032	64098055	20	-	28162770	OCIAML5	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	0.7177890374669509	[31]	[94]	6	hSpCas9	negative selection	11221130
64098095	64098118	20	-	28162770	OCIAML5	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.14047762421695564	[290]	[578]	1	hSpCas9	negative selection	11221131
64092826	64092849	20	+	28162770	OCIAML5	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	-0.769604410672024	[169]	[179]	-5	hSpCas9	negative selection	11221132
64092737	64092760	20	-	28162770	EOL1	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-0.8156929546285325	[146]	[43]	-5	hSpCas9	negative selection	11390489
64097882	64097905	20	-	28162770	EOL1	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	-1.5648370691683906	[218]	[38]	-7	hSpCas9	negative selection	11390490
64092878	64092901	20	-	28162770	EOL1	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	0.3472738046810804	[654]	[438]	3	hSpCas9	negative selection	11390491
64097901	64097924	20	-	28162770	EOL1	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.4897470174702607	[391]	[289]	4	hSpCas9	negative selection	11390492
64092768	64092791	20	-	28162770	EOL1	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	-1.3183087523256287	[141]	[29]	-7	hSpCas9	negative selection	11390493
64092788	64092811	20	-	28162770	EOL1	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	-1.134345917483034	[124]	[29]	-6	hSpCas9	negative selection	11390494
64097849	64097872	20	-	28162770	EOL1	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.19723234743804766	[297]	[179]	1	hSpCas9	negative selection	11390495
64098032	64098055	20	-	28162770	EOL1	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	1.0419047222086935	[58]	[63]	8	hSpCas9	negative selection	11390496
64098095	64098118	20	-	28162770	EOL1	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	1.0985771713455834	[389]	[439]	8	hSpCas9	negative selection	11390497
64092826	64092849	20	+	28162770	EOL1	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	-0.15724631959311267	[253]	[119]	-1	hSpCas9	negative selection	11390498
64092737	64092760	20	-	28162770	MOLM13	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.13202209569934276	[129]	[102]	0	hSpCas9	negative selection	11559855
64097882	64097905	20	-	28162770	MOLM13	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	0.47428715274272953	[224]	[225]	3	hSpCas9	negative selection	11559856
64092878	64092901	20	-	28162770	MOLM13	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	0.14677890925823867	[440]	[352]	1	hSpCas9	negative selection	11559857
64097901	64097924	20	-	28162770	MOLM13	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.8972383568488596	[325]	[438]	6	hSpCas9	negative selection	11559858
64092768	64092791	20	-	28162770	MOLM13	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	0.16936589099216004	[106]	[86]	1	hSpCas9	negative selection	11559859
64092788	64092811	20	-	28162770	MOLM13	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	0.742328550650622	[104]	[126]	5	hSpCas9	negative selection	11559860
64097849	64097872	20	-	28162770	MOLM13	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.4586708515152001	[313]	[311]	3	hSpCas9	negative selection	11559861
64098032	64098055	20	-	28162770	MOLM13	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	-0.9689744801874434	[110]	[40]	-5	hSpCas9	negative selection	11559862
64098095	64098118	20	-	28162770	MOLM13	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.8470958888324005	[478]	[622]	6	hSpCas9	negative selection	11559863
64092826	64092849	20	+	28162770	MOLM13	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.1623868345703278	[261]	[211]	1	hSpCas9	negative selection	11559864
64092737	64092760	20	-	28162770	HEL	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.1848882491825402	[113]	[82]	1	hSpCas9	negative selection	11729221
64097882	64097905	20	-	28162770	HEL	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	0.5891577917955129	[191]	[184]	5	hSpCas9	negative selection	11729222
64092878	64092901	20	-	28162770	HEL	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	0.015071880324962428	[359]	[232]	0	hSpCas9	negative selection	11729223
64097901	64097924	20	-	28162770	HEL	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.21305455675711182	[329]	[244]	1	hSpCas9	negative selection	11729224
64092768	64092791	20	-	28162770	HEL	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	-0.5137656536796338	[106]	[47]	-3	hSpCas9	negative selection	11729225
64092788	64092811	20	-	28162770	HEL	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	-0.7606168622308513	[81]	[30]	-5	hSpCas9	negative selection	11729226
64097849	64097872	20	-	28162770	HEL	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.7100940998021215	[271]	[284]	6	hSpCas9	negative selection	11729227
64098032	64098055	20	-	28162770	HEL	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	-0.6791892628870053	[109]	[43]	-4	hSpCas9	negative selection	11729228
64098095	64098118	20	-	28162770	HEL	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.6350444402103566	[375]	[373]	5	hSpCas9	negative selection	11729229
64092826	64092849	20	+	28162770	HEL	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.28016875261564855	[278]	[216]	2	hSpCas9	negative selection	11729230
64092737	64092760	20	-	28162770	MV411	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-1.0983372860589546	[60]	[23]	-6	hSpCas9	negative selection	11898587
64097882	64097905	20	-	28162770	MV411	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	-0.4791860991619718	[138]	[83]	-4	hSpCas9	negative selection	11898588
64092878	64092901	20	-	28162770	MV411	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-0.798955354701676	[315]	[152]	-5	hSpCas9	negative selection	11898589
64097901	64097924	20	-	28162770	MV411	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.3512733617673153	[267]	[287]	3	hSpCas9	negative selection	11898590
64092768	64092791	20	-	28162770	MV411	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	-1.2688121998543664	[122]	[42]	-7	hSpCas9	negative selection	11898591
64092788	64092811	20	-	28162770	MV411	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	0.3497992684124531	[67]	[72]	3	hSpCas9	negative selection	11898592
64097849	64097872	20	-	28162770	MV411	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	1.0240593453007718	[243]	[417]	8	hSpCas9	negative selection	11898593
64098032	64098055	20	-	28162770	MV411	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	1.2025833149985148	[48]	[94]	9	hSpCas9	negative selection	11898594
64098095	64098118	20	-	28162770	MV411	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.39807896876960025	[317]	[352]	3	hSpCas9	negative selection	11898595
64092826	64092849	20	+	28162770	MV411	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	-0.8052427658934022	[250]	[120]	-5	hSpCas9	negative selection	11898596
64092737	64092760	20	-	28162770	MONOMAC1	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	2.0871715818786503	[30]	[150]	9	hSpCas9	negative selection	12067953
64097882	64097905	20	-	28162770	MONOMAC1	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	0.04112289013521087	[116]	[137]	0	hSpCas9	negative selection	12067954
64092878	64092901	20	-	28162770	MONOMAC1	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-0.1171835393703391	[245]	[259]	-1	hSpCas9	negative selection	12067955
64097901	64097924	20	-	28162770	MONOMAC1	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.11723767528437345	[188]	[234]	1	hSpCas9	negative selection	12067956
64092768	64092791	20	-	28162770	MONOMAC1	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	0.4096207247609216	[43]	[66]	4	hSpCas9	negative selection	12067957
64092788	64092811	20	-	28162770	MONOMAC1	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	-0.15521667136492678	[33]	[34]	-1	hSpCas9	negative selection	12067958
64097849	64097872	20	-	28162770	MONOMAC1	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.6659822501130492	[137]	[250]	6	hSpCas9	negative selection	12067959
64098032	64098055	20	-	28162770	MONOMAC1	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	-1.1356363023954106	[45]	[23]	-7	hSpCas9	negative selection	12067960
64098095	64098118	20	-	28162770	MONOMAC1	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.6766467031590457	[166]	[305]	6	hSpCas9	negative selection	12067961
64092826	64092849	20	+	28162770	MONOMAC1	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.7769679444075018	[111]	[219]	7	hSpCas9	negative selection	12067962
64092737	64092760	20	-	28162770	OCIAML2	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	-1.3775204208506797	[14]	[31]	-7	hSpCas9	negative selection	12237319
64097882	64097905	20	-	28162770	OCIAML2	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	-0.09211820198843135	[19]	[103]	-1	hSpCas9	negative selection	12237320
64092878	64092901	20	-	28162770	OCIAML2	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	-0.5744656362267011	[53]	[200]	-4	hSpCas9	negative selection	12237321
64097901	64097924	20	-	28162770	OCIAML2	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	0.5971147813936729	[38]	[326]	6	hSpCas9	negative selection	12237322
64092768	64092791	20	-	28162770	OCIAML2	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	0.09230636914899604	[10]	[64]	0	hSpCas9	negative selection	12237323
64092788	64092811	20	-	28162770	OCIAML2	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	-0.39262731324088795	[8]	[37]	-3	hSpCas9	negative selection	12237324
64097849	64097872	20	-	28162770	OCIAML2	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.3914909002463348	[47]	[348]	4	hSpCas9	negative selection	12237325
64098032	64098055	20	-	28162770	OCIAML2	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	0.6233463229668523	[12]	[110]	6	hSpCas9	negative selection	12237326
64098095	64098118	20	-	28162770	OCIAML2	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	0.05132287795319446	[77]	[447]	0	hSpCas9	negative selection	12237327
64092826	64092849	20	+	28162770	OCIAML2	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.02963551090371376	[37]	[214]	0	hSpCas9	negative selection	12237328
64092737	64092760	20	-	28162770	OCIAML3	viability	GATAACCTCCCAGAACGGCGCGG	OPRL1	ENSG00000125510	0.4059923596758367	[24]	[99]	4	hSpCas9	negative selection	12406685
64097882	64097905	20	-	28162770	OCIAML3	viability	GAGGATGTCCGTGCCCTGGAAGG	OPRL1	ENSG00000125510	0.023744795514662576	[28]	[88]	0	hSpCas9	negative selection	12406686
64092878	64092901	20	-	28162770	OCIAML3	viability	GGCCAGGTAGAGCCCCACGATGG	OPRL1	ENSG00000125510	0.11521296335913889	[62]	[205]	1	hSpCas9	negative selection	12406687
64097901	64097924	20	-	28162770	OCIAML3	viability	CAAACGGCCAGAAGCCCAGGAGG	OPRL1	ENSG00000125510	-0.17316451936411345	[61]	[165]	-1	hSpCas9	negative selection	12406688
64092768	64092791	20	-	28162770	OCIAML3	viability	GGGACAGGTTGCCCTGAAGGTGG	OPRL1	ENSG00000125510	0.8119847193516736	[19]	[105]	7	hSpCas9	negative selection	12406689
64092788	64092811	20	-	28162770	OCIAML3	viability	ACTGTGGTTGGGGCTCAGGAGGG	OPRL1	ENSG00000125510	1.0174270717581844	[8]	[54]	8	hSpCas9	negative selection	12406690
64097849	64097872	20	-	28162770	OCIAML3	viability	CAGGACCAGAGTGTCGGCCAGGG	OPRL1	ENSG00000125510	0.8714645804704336	[64]	[358]	7	hSpCas9	negative selection	12406691
64098032	64098055	20	-	28162770	OCIAML3	viability	GCGGACGTCGAGGGCACGGATGG	OPRL1	ENSG00000125510	-0.9350445581592302	[18]	[29]	-6	hSpCas9	negative selection	12406692
64098095	64098118	20	-	28162770	OCIAML3	viability	AACACCGACAACAGAGGCCAGGG	OPRL1	ENSG00000125510	-0.14554713950786913	[95]	[261]	-1	hSpCas9	negative selection	12406693
64092826	64092849	20	+	28162770	OCIAML3	viability	CTGCTGCTCAATGCCAGCCACGG	OPRL1	ENSG00000125510	0.9120994396857534	[46]	[266]	7	hSpCas9	negative selection	12406694