| 58169657 | 58169680 | 17 | + | 26627737 | DLD1 | viability | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.2053887424435581 | [181] | [59,69,22] | -2 | hSpCas9 | negative selection | 799015 | 58170445 | 58170468 | 17 | - | 26627737 | DLD1 | viability | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | -0.22927268494984304 | [693] | [124,247,184] | -2 | hSpCas9 | negative selection | 799016 | 58170548 | 58170571 | 17 | + | 26627737 | DLD1 | viability | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -0.4868561540864049 | [289] | [85,41,64] | -5 | hSpCas9 | negative selection | 799017 | 58170567 | 58170590 | 17 | - | 26627737 | DLD1 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -0.24483585709570477 | [208] | [18,74,69] | -3 | hSpCas9 | negative selection | 799018 | 58169657 | 58169680 | 17 | + | 26627737 | GBM cells | viability after 5 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.412547220950608 | [205] | [76,88] | -6 | hSpCas9 | negative selection | 881330 | 58170445 | 58170468 | 17 | - | 26627737 | GBM cells | viability after 5 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 0.44205619991221473 | [349] | [282,226] | 6 | hSpCas9 | negative selection | 881331 | 58170548 | 58170571 | 17 | + | 26627737 | GBM cells | viability after 5 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -1.1435213914347109 | [275] | [68,64] | -9 | hSpCas9 | negative selection | 881332 | 58170567 | 58170590 | 17 | - | 26627737 | GBM cells | viability after 5 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.23995079272075248 | [104] | [77,54] | 4 | hSpCas9 | negative selection | 881333 | 58169657 | 58169680 | 17 | + | 26627737 | GBM cells | viability after 13 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.09338844375349159 | [205] | [117,93] | -1 | hSpCas9 | negative selection | 963645 | 58170445 | 58170468 | 17 | - | 26627737 | GBM cells | viability after 13 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 0.2572068225855129 | [349] | [221,230] | 3 | hSpCas9 | negative selection | 963646 | 58170548 | 58170571 | 17 | + | 26627737 | GBM cells | viability after 13 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -1.8457692880719623 | [275] | [55,29] | -9 | hSpCas9 | negative selection | 963647 | 58170567 | 58170590 | 17 | - | 26627737 | GBM cells | viability after 13 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -0.0892881055278072 | [104] | [52,53] | -1 | hSpCas9 | negative selection | 963648 | 58169657 | 58169680 | 17 | + | 26627737 | GBM cells | viability after 21 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.6248112483355399 | [205] | [58,84] | -5 | hSpCas9 | negative selection | 1045960 | 58170445 | 58170468 | 17 | - | 26627737 | GBM cells | viability after 21 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 0.1681652085871151 | [349] | [209,216] | 1 | hSpCas9 | negative selection | 1045961 | 58170548 | 58170571 | 17 | + | 26627737 | GBM cells | viability after 21 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -2.019271098351922 | [275] | [48,25] | -9 | hSpCas9 | negative selection | 1045962 | 58170567 | 58170590 | 17 | - | 26627737 | GBM cells | viability after 21 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.16748980711476746 | [104] | [85,43] | 1 | hSpCas9 | negative selection | 1045963 | 58169657 | 58169680 | 17 | + | 26627737 | RPE1 | viability after 9 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | 0.9125741168020306 | [410] | [253,226] | 6 | hSpCas9 | negative selection | 1128275 | 58170445 | 58170468 | 17 | - | 26627737 | RPE1 | viability after 9 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | -0.238439755291319 | [1762] | [428,517] | -2 | hSpCas9 | negative selection | 1128276 | 58170548 | 58170571 | 17 | + | 26627737 | RPE1 | viability after 9 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | 0.00022663097952962952 | [604] | [157,229] | 0 | hSpCas9 | negative selection | 1128277 | 58170567 | 58170590 | 17 | - | 26627737 | RPE1 | viability after 9 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -0.7305458293610171 | [476] | [89,89] | -5 | hSpCas9 | negative selection | 1128278 | 58169657 | 58169680 | 17 | + | 26627737 | RPE1 | viability after 12 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | 0.03621106301447219 | [410] | [120,104] | 0 | hSpCas9 | negative selection | 1210590 | 58170445 | 58170468 | 17 | - | 26627737 | RPE1 | viability after 12 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 0.1439072498587186 | [1762] | [466,582] | 1 | hSpCas9 | negative selection | 1210591 | 58170548 | 58170571 | 17 | + | 26627737 | RPE1 | viability after 12 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | 0.14740215688107752 | [604] | [180,178] | 1 | hSpCas9 | negative selection | 1210592 | 58170567 | 58170590 | 17 | - | 26627737 | RPE1 | viability after 12 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -0.3329503409142772 | [476] | [160,38] | -2 | hSpCas9 | negative selection | 1210593 | 58169657 | 58169680 | 17 | + | 26627737 | RPE1 | viability after 15 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.14048688518499142 | [410] | [134,76] | -1 | hSpCas9 | negative selection | 1292905 | 58170445 | 58170468 | 17 | - | 26627737 | RPE1 | viability after 15 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | -0.165918134053763 | [1762] | [301,581] | -1 | hSpCas9 | negative selection | 1292906 | 58170548 | 58170571 | 17 | + | 26627737 | RPE1 | viability after 15 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -0.6081364642289909 | [604] | [152,72] | -4 | hSpCas9 | negative selection | 1292907 | 58170567 | 58170590 | 17 | - | 26627737 | RPE1 | viability after 15 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -0.9546216659106573 | [476] | [118,21] | -6 | hSpCas9 | negative selection | 1292908 | 58169657 | 58169680 | 17 | + | 26627737 | RPE1 | viability after 18 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | 0.15915961904083198 | [410] | [104,143] | 1 | hSpCas9 | negative selection | 1375220 | 58170445 | 58170468 | 17 | - | 26627737 | RPE1 | viability after 18 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | -0.1617198202448391 | [1762] | [361,492] | -1 | hSpCas9 | negative selection | 1375221 | 58170548 | 58170571 | 17 | + | 26627737 | RPE1 | viability after 18 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | 0.1552056628046998 | [604] | [190,171] | 1 | hSpCas9 | negative selection | 1375222 | 58170567 | 58170590 | 17 | - | 26627737 | RPE1 | viability after 18 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -0.5409193530034241 | [476] | [116,57] | -3 | hSpCas9 | negative selection | 1375223 | 58169657 | 58169680 | 17 | + | 26627737 | HeLa | viability after 8 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -1.6682163081163601 | [532] | [150,69,18] | -9 | hSpCas9 | negative selection | 1457535 | 58170445 | 58170468 | 17 | - | 26627737 | HeLa | viability after 8 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 1.714797929964491 | [186] | [277,277,248] | 9 | hSpCas9 | negative selection | 1457536 | 58170548 | 58170571 | 17 | + | 26627737 | HeLa | viability after 8 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -0.5757429237529457 | [315] | [120,23,134] | -5 | hSpCas9 | negative selection | 1457537 | 58170567 | 58170590 | 17 | - | 26627737 | HeLa | viability after 8 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -1.3637197229970583 | [247] | [59,45,24] | -8 | hSpCas9 | negative selection | 1457538 | 58169657 | 58169680 | 17 | + | 26627737 | HeLa | viability after 12 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -1.1949088273875594 | [532] | [226,24,47] | -8 | hSpCas9 | negative selection | 1539850 | 58170445 | 58170468 | 17 | - | 26627737 | HeLa | viability after 12 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 1.457948387095479 | [186] | [329,205,104] | 8 | hSpCas9 | negative selection | 1539851 | 58170548 | 58170571 | 17 | + | 26627737 | HeLa | viability after 12 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -0.6574159569536151 | [315] | [52,49,147] | -5 | hSpCas9 | negative selection | 1539852 | 58170567 | 58170590 | 17 | - | 26627737 | HeLa | viability after 12 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.42047572914842196 | [247] | [142,152,113] | 3 | hSpCas9 | negative selection | 1539853 | 58169657 | 58169680 | 17 | + | 26627737 | HeLa | viability after 15 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -1.2231541361390343 | [532] | [43,123,112] | -8 | hSpCas9 | negative selection | 1622165 | 58170445 | 58170468 | 17 | - | 26627737 | HeLa | viability after 15 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 1.9323935151958467 | [186] | [283,318,266] | 9 | hSpCas9 | negative selection | 1622166 | 58170548 | 58170571 | 17 | + | 26627737 | HeLa | viability after 15 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -0.12385185261308179 | [315] | [157,133,56] | -1 | hSpCas9 | negative selection | 1622167 | 58170567 | 58170590 | 17 | - | 26627737 | HeLa | viability after 15 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.33412548465142916 | [247] | [196,103,75] | 3 | hSpCas9 | negative selection | 1622168 | 58169657 | 58169680 | 17 | + | 26627737 | HeLa | viability after 18 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -1.1474722106202004 | [532] | [30,112,112] | -7 | hSpCas9 | negative selection | 1704480 | 58170445 | 58170468 | 17 | - | 26627737 | HeLa | viability after 18 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 1.9219751119584245 | [186] | [188,260,266] | 9 | hSpCas9 | negative selection | 1704481 | 58170548 | 58170571 | 17 | + | 26627737 | HeLa | viability after 18 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -0.13000414053176268 | [315] | [104,110,56] | -1 | hSpCas9 | negative selection | 1704482 | 58170567 | 58170590 | 17 | - | 26627737 | HeLa | viability after 18 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.415293135941115 | [247] | [140,92,75] | 3 | hSpCas9 | negative selection | 1704483 | 58169657 | 58169680 | 17 | + | 26627737 | HCT116 | viability after 6 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | 0.06480774520657756 | [497] | [97,72] | 0 | hSpCas9 | negative selection | 1786795 | 58170445 | 58170468 | 17 | - | 26627737 | HCT116 | viability after 6 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 1.5977247447315288 | [221] | [191,57] | 7 | hSpCas9 | negative selection | 1786796 | 58170548 | 58170571 | 17 | + | 26627737 | HCT116 | viability after 6 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -0.8153953752199345 | [623] | [125,16] | -5 | hSpCas9 | negative selection | 1786797 | 58170567 | 58170590 | 17 | - | 26627737 | HCT116 | viability after 6 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -0.3345253948141298 | [169] | [55,1] | -2 | hSpCas9 | negative selection | 1786798 | 58169657 | 58169680 | 17 | + | 26627737 | HCT116 | viability after 8 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | 0.06189280099179806 | [210] | [178,54,130] | 0 | hSpCas9 | negative selection | 1869110 | 58170445 | 58170468 | 17 | - | 26627737 | HCT116 | viability after 8 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 0.027713270120843014 | [456] | [279,272,217] | 0 | hSpCas9 | negative selection | 1869111 | 58170548 | 58170571 | 17 | + | 26627737 | HCT116 | viability after 8 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -0.9357005496408208 | [287] | [88,76,82] | -8 | hSpCas9 | negative selection | 1869112 | 58170567 | 58170590 | 17 | - | 26627737 | HCT116 | viability after 8 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.7400984298715398 | [101] | [65,109,104] | 7 | hSpCas9 | negative selection | 1869113 | 58169657 | 58169680 | 17 | + | 26627737 | HCT116 | viability after 9 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.011701512515529477 | [497] | [232,51] | 0 | hSpCas9 | negative selection | 1951425 | 58170445 | 58170468 | 17 | - | 26627737 | HCT116 | viability after 9 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 1.98836240261729 | [221] | [175,281] | 9 | hSpCas9 | negative selection | 1951426 | 58170548 | 58170571 | 17 | + | 26627737 | HCT116 | viability after 9 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -0.9133209646568305 | [623] | [21,140] | -6 | hSpCas9 | negative selection | 1951427 | 58170567 | 58170590 | 17 | - | 26627737 | HCT116 | viability after 9 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 1.346053237134865 | [169] | [82,140] | 8 | hSpCas9 | negative selection | 1951428 | 58169657 | 58169680 | 17 | + | 26627737 | HCT116 | viability after 12 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.45318622786623497 | [210] | [139,47,48] | -5 | hSpCas9 | negative selection | 2033740 | 58170445 | 58170468 | 17 | - | 26627737 | HCT116 | viability after 12 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | -0.30467940710754954 | [456] | [179,210,193] | -3 | hSpCas9 | negative selection | 2033741 | 58170548 | 58170571 | 17 | + | 26627737 | HCT116 | viability after 12 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -1.008931347016835 | [287] | [71,78,74] | -8 | hSpCas9 | negative selection | 2033742 | 58170567 | 58170590 | 17 | - | 26627737 | HCT116 | viability after 12 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.4475808556923433 | [101] | [55,80,83] | 4 | hSpCas9 | negative selection | 2033743 | 58169657 | 58169680 | 17 | + | 26627737 | HCT116 | viability after 15 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.21950451223130996 | [210] | [122,43,146] | -2 | hSpCas9 | negative selection | 2116055 | 58170445 | 58170468 | 17 | - | 26627737 | HCT116 | viability after 15 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | -0.05662856308325959 | [456] | [396,236,141] | 0 | hSpCas9 | negative selection | 2116056 | 58170548 | 58170571 | 17 | + | 26627737 | HCT116 | viability after 15 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -0.8772131451295293 | [287] | [121,59,91] | -7 | hSpCas9 | negative selection | 2116057 | 58170567 | 58170590 | 17 | - | 26627737 | HCT116 | viability after 15 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.052310996826520295 | [101] | [42,70,65] | 0 | hSpCas9 | negative selection | 2116058 | 58169657 | 58169680 | 17 | + | 26627737 | HCT116 | viability after 18 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.5019325476057398 | [210] | [99,69,44] | -4 | hSpCas9 | negative selection | 2198370 | 58170445 | 58170468 | 17 | - | 26627737 | HCT116 | viability after 18 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | -0.5637029637661155 | [456] | [221,131,92] | -5 | hSpCas9 | negative selection | 2198371 | 58170548 | 58170571 | 17 | + | 26627737 | HCT116 | viability after 18 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | -0.8253387994164141 | [287] | [79,49,108] | -6 | hSpCas9 | negative selection | 2198372 | 58170567 | 58170590 | 17 | - | 26627737 | HCT116 | viability after 18 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.8251622411288045 | [101] | [73,127,55] | 6 | hSpCas9 | negative selection | 2198373 | 58169921 | 58169944 | 17 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | AAGAAAACCATCTCTTACCAGGG | OR4D2 | ENSG00000255713 | 0.08844259240460906 | [5,4] | [3,5] | 1 | hSpCas9 | positive selection | 3008125 | 58170040 | 58170063 | 17 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | ATGACGGTGACATAGCGGAGGGG | OR4D2 | ENSG00000255713 | -0.15855850058858584 | [2,2] | [1,2] | -2 | hSpCas9 | positive selection | 3008126 | 58169659 | 58169682 | 17 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGAAACAGGGAACCTCACGTGGG | OR4D2 | ENSG00000255713 | -0.35410686437143646 | [2,3] | [3,0] | -5 | hSpCas9 | positive selection | 3008127 | 58169827 | 58169850 | 17 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TTTCGGAGCAGAAAGTACATGGG | OR4D2 | ENSG00000255713 | 0.4106042697124457 | [3,4] | [4,4] | 8 | hSpCas9 | positive selection | 3008128 | 58169921 | 58169944 | 17 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | AAGAAAACCATCTCTTACCAGGG | OR4D2 | ENSG00000255713 | -0.0793232586297628 | [5,5] | [5,1] | -1 | hSpCas9 | positive selection | 3075983 | 58170040 | 58170063 | 17 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | ATGACGGTGACATAGCGGAGGGG | OR4D2 | ENSG00000255713 | -0.027928856898235765 | [2,2] | [2,0] | 0 | hSpCas9 | positive selection | 3075984 | 58169659 | 58169682 | 17 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGAAACAGGGAACCTCACGTGGG | OR4D2 | ENSG00000255713 | -0.09660402432600076 | [2,2] | [2,1] | -1 | hSpCas9 | positive selection | 3075985 | 58169827 | 58169850 | 17 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TTTCGGAGCAGAAAGTACATGGG | OR4D2 | ENSG00000255713 | -0.7359860296881562 | [3,3] | [2,0] | -8 | hSpCas9 | positive selection | 3075986 | 58169670 | 58169693 | | - | 24336571 | A375 | resistance to PLX after 7 days | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | -0.039996919218146854 | [13,14] | [14,13] | -1 | hSpCas9 | positive selection | 3132877 | 58170056 | 58170079 | | + | 24336571 | A375 | resistance to PLX after 7 days | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.0023985511011147542 | [14,15] | [14,15] | 0 | hSpCas9 | positive selection | 3132878 | 58169670 | 58169693 | | - | 24336571 | A375 | resistance to PLX after 14 days | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.6257259482223376 | [11,11] | [7,8] | 5 | hSpCas9 | positive selection | 3190670 | 58170056 | 58170079 | | + | 24336571 | A375 | resistance to PLX after 14 days | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.6805290468231295 | [18,12] | [11,11] | 6 | hSpCas9 | positive selection | 3190671 | 58169670 | 58169693 | | - | 24336571 | A375 | viability after 7 days | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.40983614296751614 | [10] | [13,14] | 6 | hSpCas9 | negative selection | 3248463 | 58170056 | 58170079 | | + | 24336571 | A375 | viability after 7 days | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.11718058264681147 | [17] | [14,15] | -2 | hSpCas9 | negative selection | 3248464 | 58169670 | 58169693 | | - | 24336571 | A375 | viability after 14 days | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.17659840575571312 | [10] | [11,11] | 2 | hSpCas9 | negative selection | 3306256 | 58170056 | 58170079 | | + | 24336571 | A375 | viability after 14 days | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.05779969907441024 | [17] | [18,12] | 0 | hSpCas9 | negative selection | 3306257 | 58169832 | 58169855 | 17 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | 1.0285075209499543 | [74,74] | [0,0] | 5 | hSpCas9 | positive selection | 3383550 | 58170056 | 58170079 | 17 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 10.842971644743479 | [175,175] | [2112,2112] | 9 | hSpCas9 | positive selection | 3383551 | 58170305 | 58170328 | 17 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | 0.9719239925835867 | [155,155] | [1,1] | 4 | hSpCas9 | positive selection | 3383552 | 58169920 | 58169943 | 17 | + | 26780180 | HT29 | viability (Avana library 4 designs) | AAGAAAACCATCTCTTACCAGGG | OR4D2 | ENSG00000255713 | 0.732246093256619 | [] | [] | 3 | hSpCas9 | negative selection | 3446088 | 58170040 | 58170063 | 17 | - | 26780180 | HT29 | viability (Avana library 4 designs) | ATGACGGTGACATAGCGGAGGGG | OR4D2 | ENSG00000255713 | 1.78566772315425 | [] | [] | 6 | hSpCas9 | negative selection | 3446089 | 58169658 | 58169681 | 17 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GGAAACAGGGAACCTCACGTGGG | OR4D2 | ENSG00000255713 | 3.29282650519053 | [] | [] | 8 | hSpCas9 | negative selection | 3446090 | 58169827 | 58169850 | 17 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TTTCGGAGCAGAAAGTACATGGG | OR4D2 | ENSG00000255713 | 2.09646740511405 | [] | [] | 7 | hSpCas9 | negative selection | 3446091 | 58169827 | 58169850 | 17 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TTTCGGAGCAGAAAGTACATGGG | OR4D2 | ENSG00000255713 | 1.07552527036355 | [] | [] | 1 | hSpCas9 | negative selection | 3539189 | 58169658 | 58169681 | 17 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGAAACAGGGAACCTCACGTGGG | OR4D2 | ENSG00000255713 | 0.591995101334775 | [] | [] | 0 | hSpCas9 | negative selection | 3539190 | 58170040 | 58170063 | 17 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ATGACGGTGACATAGCGGAGGGG | OR4D2 | ENSG00000255713 | 4.44504542641591 | [] | [] | 7 | hSpCas9 | negative selection | 3539191 | 58169920 | 58169943 | 17 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AAGAAAACCATCTCTTACCAGGG | OR4D2 | ENSG00000255713 | -7.37225003497036 | [] | [] | -6 | hSpCas9 | negative selection | 3539192 | 58170041 | 58170064 | 17 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CATGACGGTGACATAGCGGAGGG | OR4D2 | ENSG00000255713 | 5.62459767194669 | [] | [] | 8 | hSpCas9 | negative selection | 3539193 | 58170056 | 58170079 | 17 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCAGAGCTGAGTGTTCATGACGG | OR4D2 | ENSG00000255713 | 4.10942310568693 | [] | [] | 6 | hSpCas9 | negative selection | 3539194 | 58169827 | 58169850 | 17 | - | 26780180 | A375 | viability (Avana lentiGuide) | TTTCGGAGCAGAAAGTACATGGG | OR4D2 | ENSG00000255713 | 3.05910853012385 | [] | [] | 3 | hSpCas9 | negative selection | 3647848 | 58169658 | 58169681 | 17 | + | 26780180 | A375 | viability (Avana lentiGuide) | GGAAACAGGGAACCTCACGTGGG | OR4D2 | ENSG00000255713 | -0.458196452321489 | [] | [] | 0 | hSpCas9 | negative selection | 3647849 | 58170040 | 58170063 | 17 | - | 26780180 | A375 | viability (Avana lentiGuide) | ATGACGGTGACATAGCGGAGGGG | OR4D2 | ENSG00000255713 | 1.51063146972349 | [] | [] | 1 | hSpCas9 | negative selection | 3647850 | 58169920 | 58169943 | 17 | + | 26780180 | A375 | viability (Avana lentiGuide) | AAGAAAACCATCTCTTACCAGGG | OR4D2 | ENSG00000255713 | 1.76776645358229 | [] | [] | 2 | hSpCas9 | negative selection | 3647851 | 58170041 | 58170064 | 17 | - | 26780180 | A375 | viability (Avana lentiGuide) | CATGACGGTGACATAGCGGAGGG | OR4D2 | ENSG00000255713 | 5.91697145369458 | [] | [] | 5 | hSpCas9 | negative selection | 3647852 | 58170056 | 58170079 | 17 | - | 26780180 | A375 | viability (Avana lentiGuide) | CCAGAGCTGAGTGTTCATGACGG | OR4D2 | ENSG00000255713 | -1.11000015508441 | [] | [] | -2 | hSpCas9 | negative selection | 3647853 | 58169827 | 58169850 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TTTCGGAGCAGAAAGTACATGGG | OR4D2 | ENSG00000255713 | -0.13797345836566066 | [5] | [5,4] | -2 | hSpCas9 | positive selection | 3756507 | 58169658 | 58169681 | 17 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGAAACAGGGAACCTCACGTGGG | OR4D2 | ENSG00000255713 | -0.12329040932157945 | [4] | [4,3] | -2 | hSpCas9 | positive selection | 3756508 | 58170040 | 58170063 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ATGACGGTGACATAGCGGAGGGG | OR4D2 | ENSG00000255713 | 0.3281281600347363 | [4] | [5,5] | 8 | hSpCas9 | positive selection | 3756509 | 58169920 | 58169943 | 17 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AAGAAAACCATCTCTTACCAGGG | OR4D2 | ENSG00000255713 | -0.35812614585397884 | [7] | [5,5] | -5 | hSpCas9 | positive selection | 3756510 | 58170041 | 58170064 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CATGACGGTGACATAGCGGAGGG | OR4D2 | ENSG00000255713 | 0.30415885822810507 | [4] | [6,5] | 8 | hSpCas9 | positive selection | 3756511 | 58170056 | 58170079 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCAGAGCTGAGTGTTCATGACGG | OR4D2 | ENSG00000255713 | 0.21239352854354407 | [5] | [7,6] | 6 | hSpCas9 | positive selection | 3756512 | 58169827 | 58169850 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TTTCGGAGCAGAAAGTACATGGG | OR4D2 | ENSG00000255713 | 0.04315893649226622 | [6] | [4,6] | 0 | hSpCas9 | positive selection | 3865114 | 58169658 | 58169681 | 17 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGAAACAGGGAACCTCACGTGGG | OR4D2 | ENSG00000255713 | -0.3348409559023395 | [5] | [4,2] | -4 | hSpCas9 | positive selection | 3865115 | 58170040 | 58170063 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ATGACGGTGACATAGCGGAGGGG | OR4D2 | ENSG00000255713 | -0.5512269033492297 | [4] | [1,3] | -6 | hSpCas9 | positive selection | 3865116 | 58169920 | 58169943 | 17 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AAGAAAACCATCTCTTACCAGGG | OR4D2 | ENSG00000255713 | 0.3165580060026741 | [6] | [7,7] | 8 | hSpCas9 | positive selection | 3865117 | 58170041 | 58170064 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CATGACGGTGACATAGCGGAGGG | OR4D2 | ENSG00000255713 | -0.07228088229895774 | [4] | [3,4] | -1 | hSpCas9 | positive selection | 3865118 | 58170056 | 58170079 | 17 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCAGAGCTGAGTGTTCATGACGG | OR4D2 | ENSG00000255713 | 0.22664018969122646 | [7] | [7,6] | 6 | hSpCas9 | positive selection | 3865119 | 58170398 | 58170421 | 17 | - | 26780180 | A375 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 1.20997164271845 | [] | [] | 6 | hSpCas9 | negative selection | 3976147 | 58170567 | 58170590 | 17 | - | 26780180 | A375 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.690145607996825 | [] | [] | 2 | hSpCas9 | negative selection | 3976148 | 58169670 | 58169693 | 17 | - | 26780180 | A375 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.903034461386131 | [] | [] | 4 | hSpCas9 | negative selection | 3976149 | 58170305 | 58170328 | 17 | - | 26780180 | A375 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | 1.17991510595363 | [] | [] | 6 | hSpCas9 | negative selection | 3976150 | 58170056 | 58170079 | 17 | + | 26780180 | A375 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 1.65671723386799 | [] | [] | 8 | hSpCas9 | negative selection | 3976151 | 58169832 | 58169855 | 17 | + | 26780180 | A375 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | 1.09486593012425 | [] | [] | 5 | hSpCas9 | negative selection | 3976152 | 58170398 | 58170421 | 17 | - | 26780180 | HT29 | viability (GeCKOv2 library) | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 1.24831450497291 | [] | [] | 6 | hSpCas9 | negative selection | 4084113 | 58170567 | 58170590 | 17 | - | 26780180 | HT29 | viability (GeCKOv2 library) | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.477110154117204 | [] | [] | 1 | hSpCas9 | negative selection | 4084114 | 58169670 | 58169693 | 17 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.593751440439057 | [] | [] | 2 | hSpCas9 | negative selection | 4084115 | 58170305 | 58170328 | 17 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | 1.60280075687179 | [] | [] | 8 | hSpCas9 | negative selection | 4084116 | 58170056 | 58170079 | 17 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 1.37976663796503 | [] | [] | 7 | hSpCas9 | negative selection | 4084117 | 58169832 | 58169855 | 17 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | 1.99729980140419 | [] | [] | 9 | hSpCas9 | negative selection | 4084118 | 58169670 | 58169693 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | -0.01479768768156109 | [4] | [2,3] | 0 | hSpCas9 | positive selection | 4157681 | 58170056 | 58170079 | 17 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.15466307839247262 | [4] | [2,3] | 4 | hSpCas9 | positive selection | 4157682 | 58169670 | 58169693 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | -0.14346320896956835 | [3] | [0,3,1,0] | -2 | hSpCas9 | positive selection | 4221703 | 58170056 | 58170079 | 17 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.0842279680558043 | [3] | [4,0,1,0] | 0 | hSpCas9 | positive selection | 4221704 | 58169670 | 58169693 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.10722388882577119 | [3] | [3,2] | 2 | hSpCas9 | positive selection | 4287624 | 58170567 | 58170590 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.29593070419093837 | [2] | [2,1] | 6 | hSpCas9 | positive selection | 4287625 | 58170398 | 58170421 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | -0.07239422405599083 | [2] | [2,0] | -1 | hSpCas9 | positive selection | 4287626 | 58169832 | 58169855 | 17 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.393643150469479 | [2] | [1,0] | -7 | hSpCas9 | positive selection | 4351880 | 58170056 | 58170079 | 17 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.5290935851360605 | [3] | [2,0] | -8 | hSpCas9 | positive selection | 4351881 | 58170305 | 58170328 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.013092458010871168 | [3] | [3,1] | 0 | hSpCas9 | positive selection | 4351882 | 58169658 | 58169681 | 17 | + | 27661255 | K562 | viability | GGAAACAGGGAACCTCACGTGGG | OR4D2 | ENSG00000255713 | 0.014432190383560972 | [834,1040] | [796,716] | 0 | dCas9-KRAB | negative selection | 5498965 | 58170081 | 58170104 | 17 | + | 27661255 | K562 | viability | GGGGCTGGTGGTAGCCACCTGGG | OR4D2 | ENSG00000255713 | 0.08058715434631417 | [656,781] | [661,557] | 3 | dCas9-KRAB | negative selection | 5498966 | 58170117 | 58170140 | 17 | - | 27661255 | K562 | viability | GAGCCAGCTGGACAATAGAGTGG | OR4D2 | ENSG00000255713 | 0.34359821418669395 | [694,836] | [809,742] | 9 | dCas9-KRAB | negative selection | 5498967 | 58169670 | 58169693 | 17 | - | 27260156 | BXPC3 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.3299472738149106 | [692] | [848,736,965,1129] | 7 | hSpCas9 | negative selection | 5560084 | 58170567 | 58170590 | 17 | - | 27260156 | BXPC3 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.5418579063946625 | [239] | [446,329,314,357] | 9 | hSpCas9 | negative selection | 5560085 | 58170398 | 58170421 | 17 | - | 27260156 | BXPC3 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.37278201489635443 | [293] | [365,399,356,478] | 7 | hSpCas9 | negative selection | 5560086 | 58169832 | 58169855 | 17 | + | 27260156 | BXPC3 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.10135576419951431 | [272] | [258,244,277,284] | -2 | hSpCas9 | negative selection | 5624340 | 58170056 | 58170079 | 17 | + | 27260156 | BXPC3 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.12258610965660643 | [482] | [503,446,710,546] | 2 | hSpCas9 | negative selection | 5624341 | 58170305 | 58170328 | 17 | - | 27260156 | BXPC3 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.48116942452531025 | [479] | [522,278,255,362] | -8 | hSpCas9 | negative selection | 5624342 | 58169670 | 58169693 | 17 | - | 27260156 | A673 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.37686427679467915 | [692] | [1235,960,1195,938] | 8 | hSpCas9 | negative selection | 5681335 | 58170567 | 58170590 | 17 | - | 27260156 | A673 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.38609121441076666 | [239] | [443,389,313,364] | 8 | hSpCas9 | negative selection | 5681336 | 58170398 | 58170421 | 17 | - | 27260156 | A673 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.24295255210347583 | [293] | [474,440,428,325] | 6 | hSpCas9 | negative selection | 5681337 | 58169832 | 58169855 | 17 | + | 27260156 | A673 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.09295796328632011 | [272] | [390,236,308,302] | -2 | hSpCas9 | negative selection | 5745591 | 58170056 | 58170079 | 17 | + | 27260156 | A673 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.004976899553814557 | [482] | [517,538,541,729] | 0 | hSpCas9 | negative selection | 5745592 | 58170305 | 58170328 | 17 | - | 27260156 | A673 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.5020480874328647 | [479] | [406,381,379,461] | -8 | hSpCas9 | negative selection | 5745593 | 58169670 | 58169693 | 17 | - | 27260156 | A375 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.20459024273970006 | [692] | [1123,990,810,823] | 3 | hSpCas9 | negative selection | 5802586 | 58170567 | 58170590 | 17 | - | 27260156 | A375 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.8423132089879232 | [239] | [492,645,448,446] | 9 | hSpCas9 | negative selection | 5802587 | 58170398 | 58170421 | 17 | - | 27260156 | A375 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.2237793259296958 | [293] | [615,462,292,257] | 3 | hSpCas9 | negative selection | 5802588 | 58169832 | 58169855 | 17 | + | 27260156 | A375 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | 0.2921964784776308 | [272] | [456,248,369,456] | 4 | hSpCas9 | negative selection | 5866842 | 58170056 | 58170079 | 17 | + | 27260156 | A375 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.11221002125615648 | [482] | [374,991,537,585] | 1 | hSpCas9 | negative selection | 5866843 | 58170305 | 58170328 | 17 | - | 27260156 | A375 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.06217776327553809 | [479] | [469,778,586,363] | -1 | hSpCas9 | negative selection | 5866844 | 58169670 | 58169693 | 17 | - | 27260156 | COLO741 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.34510608170275225 | [692] | [1216,1060,1102] | 7 | hSpCas9 | negative selection | 5923837 | 58170567 | 58170590 | 17 | - | 27260156 | COLO741 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.4267317600461824 | [239] | [399,301,523] | 8 | hSpCas9 | negative selection | 5923838 | 58170398 | 58170421 | 17 | - | 27260156 | COLO741 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.5922935050265499 | [293] | [668,592,452] | 9 | hSpCas9 | negative selection | 5923839 | 58169832 | 58169855 | 17 | + | 27260156 | COLO741 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | 0.1435325191584148 | [272] | [416,373,367] | 3 | hSpCas9 | negative selection | 5988093 | 58170056 | 58170079 | 17 | + | 27260156 | COLO741 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.13496917462110744 | [482] | [885,614,556] | 3 | hSpCas9 | negative selection | 5988094 | 58170305 | 58170328 | 17 | - | 27260156 | COLO741 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.5647668156719337 | [479] | [406,443,392] | -8 | hSpCas9 | negative selection | 5988095 | 58169670 | 58169693 | 17 | - | 27260156 | CAL120 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.6115158753501223 | [692] | [1549,1279,1159] | 8 | hSpCas9 | negative selection | 6045088 | 58170567 | 58170590 | 17 | - | 27260156 | CAL120 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 1.2374014098922816 | [239] | [867,687,582] | 9 | hSpCas9 | negative selection | 6045089 | 58170398 | 58170421 | 17 | - | 27260156 | CAL120 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.14013807899742436 | [293] | [345,465,388] | 2 | hSpCas9 | negative selection | 6045090 | 58169832 | 58169855 | 17 | + | 27260156 | CAL120 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.6772241068846859 | [272] | [157,254,215] | -7 | hSpCas9 | negative selection | 6109344 | 58170056 | 58170079 | 17 | + | 27260156 | CAL120 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.2985278090006932 | [482] | [682,793,731] | 4 | hSpCas9 | negative selection | 6109345 | 58170305 | 58170328 | 17 | - | 27260156 | CAL120 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.4360830162434511 | [479] | [464,374,486] | -6 | hSpCas9 | negative selection | 6109346 | 58169670 | 58169693 | 17 | - | 27260156 | CADOES1 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.31530355095635654 | [692] | [717,904,765,819] | 5 | hSpCas9 | negative selection | 6166339 | 58170567 | 58170590 | 17 | - | 27260156 | CADOES1 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.3736627626191297 | [239] | [277,261,321,294] | 6 | hSpCas9 | negative selection | 6166340 | 58170398 | 58170421 | 17 | - | 27260156 | CADOES1 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.3366614734276868 | [293] | [339,355,320,364] | 5 | hSpCas9 | negative selection | 6166341 | 58169832 | 58169855 | 17 | + | 27260156 | CADOES1 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.1941496565215608 | [272] | [202,147,253,284] | -3 | hSpCas9 | negative selection | 6230595 | 58170056 | 58170079 | 17 | + | 27260156 | CADOES1 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.08386796690642526 | [482] | [489,432,405,363] | -1 | hSpCas9 | negative selection | 6230596 | 58170305 | 58170328 | 17 | - | 27260156 | CADOES1 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.027638116167223104 | [479] | [426,475,383,465] | 0 | hSpCas9 | negative selection | 6230597 | 58169670 | 58169693 | 17 | - | 27260156 | EWS502 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.4586688638602473 | [692] | [924,994,1229,885] | 7 | hSpCas9 | negative selection | 6287590 | 58170567 | 58170590 | 17 | - | 27260156 | EWS502 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.41607795824386784 | [239] | [313,323,264,463] | 7 | hSpCas9 | negative selection | 6287591 | 58170398 | 58170421 | 17 | - | 27260156 | EWS502 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.30606096508327496 | [293] | [385,401,321,429] | 5 | hSpCas9 | negative selection | 6287592 | 58169832 | 58169855 | 17 | + | 27260156 | EWS502 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.03553234416577722 | [272] | [274,303,219,330] | 0 | hSpCas9 | negative selection | 6351846 | 58170056 | 58170079 | 17 | + | 27260156 | EWS502 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.31461460722839135 | [482] | [781,611,554,570] | 5 | hSpCas9 | negative selection | 6351847 | 58170305 | 58170328 | 17 | - | 27260156 | EWS502 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.3606252853409103 | [479] | [225,458,345,581] | -6 | hSpCas9 | negative selection | 6351848 | 58169670 | 58169693 | 17 | - | 27260156 | EW8 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.49423699861121506 | [692] | [761,802,735,866] | 8 | hSpCas9 | negative selection | 6408841 | 58170567 | 58170590 | 17 | - | 27260156 | EW8 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.3955460080862794 | [239] | [299,239,228,262] | 7 | hSpCas9 | negative selection | 6408842 | 58170398 | 58170421 | 17 | - | 27260156 | EW8 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.01883215554678197 | [293] | [158,267,215,316] | 0 | hSpCas9 | negative selection | 6408843 | 58169832 | 58169855 | 17 | + | 27260156 | EW8 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | 0.03254830289730193 | [272] | [357,149,230,178] | 0 | hSpCas9 | negative selection | 6473097 | 58170056 | 58170079 | 17 | + | 27260156 | EW8 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.2114047312426809 | [482] | [414,511,444,436] | 4 | hSpCas9 | negative selection | 6473098 | 58170305 | 58170328 | 17 | - | 27260156 | EW8 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.20787058332706063 | [479] | [374,379,311,287] | -4 | hSpCas9 | negative selection | 6473099 | 58169670 | 58169693 | 17 | - | 27260156 | CORL105 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.3942648113377659 | [692] | [1057,789,1443,1036] | 7 | hSpCas9 | negative selection | 6530092 | 58170567 | 58170590 | 17 | - | 27260156 | CORL105 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.02822697477114422 | [239] | [412,173,232,323] | 0 | hSpCas9 | negative selection | 6530093 | 58170398 | 58170421 | 17 | - | 27260156 | CORL105 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.11969642081957577 | [293] | [409,352,308,414] | 2 | hSpCas9 | negative selection | 6530094 | 58169832 | 58169855 | 17 | + | 27260156 | CORL105 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.1312756824281256 | [272] | [290,457,219,183] | -2 | hSpCas9 | negative selection | 6594348 | 58170056 | 58170079 | 17 | + | 27260156 | CORL105 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.027684103003230896 | [482] | [590,503,524,595] | 0 | hSpCas9 | negative selection | 6594349 | 58170305 | 58170328 | 17 | - | 27260156 | CORL105 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.22227196824177198 | [479] | [451,402,489,582] | -4 | hSpCas9 | negative selection | 6594350 | 58169670 | 58169693 | 17 | - | 27260156 | HS294T | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.7050717200460289 | [692] | [593,252,531,341] | 8 | hSpCas9 | negative selection | 6651343 | 58170567 | 58170590 | 17 | - | 27260156 | HS294T | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.5381673274514012 | [239] | [181,143,95,106] | 7 | hSpCas9 | negative selection | 6651344 | 58170398 | 58170421 | 17 | - | 27260156 | HS294T | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.2341393361527398 | [293] | [154,133,95,149] | 3 | hSpCas9 | negative selection | 6651345 | 58169832 | 58169855 | 17 | + | 27260156 | HS294T | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.190546403334525 | [272] | [57,66,155,92] | -3 | hSpCas9 | negative selection | 6715599 | 58170056 | 58170079 | 17 | + | 27260156 | HS294T | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.5054262141228407 | [482] | [192,154,423,304] | 6 | hSpCas9 | negative selection | 6715600 | 58170305 | 58170328 | 17 | - | 27260156 | HS294T | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.6549722559141031 | [479] | [96,169,97,103] | -7 | hSpCas9 | negative selection | 6715601 | 58169670 | 58169693 | 17 | - | 27260156 | HCC44 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.4399324160839325 | [692] | [1244,734,1082,1241] | 7 | hSpCas9 | negative selection | 6772594 | 58170567 | 58170590 | 17 | - | 27260156 | HCC44 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.7085118035522583 | [239] | [378,308,768,384] | 9 | hSpCas9 | negative selection | 6772595 | 58170398 | 58170421 | 17 | - | 27260156 | HCC44 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.04000665875223308 | [293] | [318,399,382,261] | 0 | hSpCas9 | negative selection | 6772596 | 58169832 | 58169855 | 17 | + | 27260156 | HCC44 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.24133199897442614 | [272] | [223,260,254,296] | -4 | hSpCas9 | negative selection | 6836850 | 58170056 | 58170079 | 17 | + | 27260156 | HCC44 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.19411902497118746 | [482] | [685,442,943,511] | 3 | hSpCas9 | negative selection | 6836851 | 58170305 | 58170328 | 17 | - | 27260156 | HCC44 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.5111841284672881 | [479] | [269,427,404,403] | -6 | hSpCas9 | negative selection | 6836852 | 58169670 | 58169693 | 17 | - | 27260156 | G402 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.8976369405481389 | [692] | [1200,1491,1598,1926] | 9 | hSpCas9 | negative selection | 6893845 | 58170567 | 58170590 | 17 | - | 27260156 | G402 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.6734017956797365 | [239] | [535,508,265,562] | 8 | hSpCas9 | negative selection | 6893846 | 58170398 | 58170421 | 17 | - | 27260156 | G402 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.19616367355711167 | [293] | [203,456,518,433] | 2 | hSpCas9 | negative selection | 6893847 | 58169832 | 58169855 | 17 | + | 27260156 | G402 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.13580908438841754 | [272] | [380,260,309,269] | -2 | hSpCas9 | negative selection | 6958101 | 58170056 | 58170079 | 17 | + | 27260156 | G402 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.3798986564892649 | [482] | [839,594,217,231] | -5 | hSpCas9 | negative selection | 6958102 | 58170305 | 58170328 | 17 | - | 27260156 | G402 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.664381046804893 | [479] | [371,311,424,364] | -7 | hSpCas9 | negative selection | 6958103 | 58169670 | 58169693 | 17 | - | 27260156 | L33 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.24530447312520842 | [692] | [886,295,484,901] | 5 | hSpCas9 | negative selection | 7015096 | 58170567 | 58170590 | 17 | - | 27260156 | L33 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.2839061149054718 | [239] | [364,91,223,221] | 6 | hSpCas9 | negative selection | 7015097 | 58170398 | 58170421 | 17 | - | 27260156 | L33 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | -0.09919633580189013 | [293] | [294,82,209,265] | -2 | hSpCas9 | negative selection | 7015098 | 58169832 | 58169855 | 17 | + | 27260156 | L33 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.2953387094232037 | [272] | [319,53,102,270] | -6 | hSpCas9 | negative selection | 7079352 | 58170056 | 58170079 | 17 | + | 27260156 | L33 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.11693905920389838 | [482] | [548,209,315,529] | 2 | hSpCas9 | negative selection | 7079353 | 58170305 | 58170328 | 17 | - | 27260156 | L33 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.44270316989952196 | [479] | [309,193,217,283] | -8 | hSpCas9 | negative selection | 7079354 | 58169670 | 58169693 | 17 | - | 27260156 | K562 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.48382590359852495 | [692] | [610,825,1227,760] | 6 | hSpCas9 | negative selection | 7136347 | 58170567 | 58170590 | 17 | - | 27260156 | K562 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.18400004790004287 | [239] | [131,92,605,131] | 2 | hSpCas9 | negative selection | 7136348 | 58170398 | 58170421 | 17 | - | 27260156 | K562 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.27228926164758566 | [293] | [431,153,366,307] | 3 | hSpCas9 | negative selection | 7136349 | 58169832 | 58169855 | 17 | + | 27260156 | K562 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.3029971622865092 | [272] | [408,104,140,147] | -4 | hSpCas9 | negative selection | 7200603 | 58170056 | 58170079 | 17 | + | 27260156 | K562 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.6473202523377624 | [482] | [624,807,478,762] | 8 | hSpCas9 | negative selection | 7200604 | 58170305 | 58170328 | 17 | - | 27260156 | K562 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | 0.48068321098770417 | [479] | [565,1005,488,360] | 6 | hSpCas9 | negative selection | 7200605 | 58169670 | 58169693 | 17 | - | 27260156 | HT29 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.09348839012181609 | [692] | [746,1046,961,840] | 1 | hSpCas9 | negative selection | 7257598 | 58170567 | 58170590 | 17 | - | 27260156 | HT29 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.5540973946747386 | [239] | [405,493,374,437] | 9 | hSpCas9 | negative selection | 7257599 | 58170398 | 58170421 | 17 | - | 27260156 | HT29 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.14817308961490994 | [293] | [392,422,367,398] | 3 | hSpCas9 | negative selection | 7257600 | 58169832 | 58169855 | 17 | + | 27260156 | HT29 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.003298047300348328 | [272] | [313,408,269,333] | 0 | hSpCas9 | negative selection | 7321854 | 58170056 | 58170079 | 17 | + | 27260156 | HT29 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.029598221583562408 | [482] | [593,548,551,597] | 0 | hSpCas9 | negative selection | 7321855 | 58170305 | 58170328 | 17 | - | 27260156 | HT29 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.47592842090794035 | [479] | [417,481,357,421] | -7 | hSpCas9 | negative selection | 7321856 | 58169670 | 58169693 | 17 | - | 27260156 | MHHES1 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.1094421736381237 | [692] | [948,1062,650,742] | 2 | hSpCas9 | negative selection | 7378849 | 58170567 | 58170590 | 17 | - | 27260156 | MHHES1 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.20400655579804094 | [239] | [337,190,309,374] | 4 | hSpCas9 | negative selection | 7378850 | 58170398 | 58170421 | 17 | - | 27260156 | MHHES1 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.35339408266556016 | [293] | [510,457,340,392] | 6 | hSpCas9 | negative selection | 7378851 | 58169832 | 58169855 | 17 | + | 27260156 | MHHES1 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.09180096530317383 | [272] | [260,284,269,319] | -2 | hSpCas9 | negative selection | 7443105 | 58170056 | 58170079 | 17 | + | 27260156 | MHHES1 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.19863110490611383 | [482] | [687,643,516,638] | 3 | hSpCas9 | negative selection | 7443106 | 58170305 | 58170328 | 17 | - | 27260156 | MHHES1 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.16968372362027614 | [479] | [593,597,366,396] | -3 | hSpCas9 | negative selection | 7443107 | 58169670 | 58169693 | 17 | - | 27260156 | MEWO | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.12418322217402178 | [692] | [714,775,629] | 2 | hSpCas9 | negative selection | 7500100 | 58170567 | 58170590 | 17 | - | 27260156 | MEWO | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.6658964597526894 | [239] | [454,307,324] | 9 | hSpCas9 | negative selection | 7500101 | 58170398 | 58170421 | 17 | - | 27260156 | MEWO | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.2391387423352781 | [293] | [374,245,362] | 5 | hSpCas9 | negative selection | 7500102 | 58169832 | 58169855 | 17 | + | 27260156 | MEWO | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.4147683052807255 | [272] | [188,238,145] | -7 | hSpCas9 | negative selection | 7564356 | 58170056 | 58170079 | 17 | + | 27260156 | MEWO | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.26432305299319825 | [482] | [357,389,376] | -5 | hSpCas9 | negative selection | 7564357 | 58170305 | 58170328 | 17 | - | 27260156 | MEWO | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.5642477023518744 | [479] | [323,301,288] | -8 | hSpCas9 | negative selection | 7564358 | 58169670 | 58169693 | 17 | - | 27260156 | LNCAPCLONEFGC | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.233349574689388 | [692] | [686,810,848,616] | 3 | hSpCas9 | negative selection | 7621351 | 58170567 | 58170590 | 17 | - | 27260156 | LNCAPCLONEFGC | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.7729362960191177 | [239] | [374,455,323,317] | 9 | hSpCas9 | negative selection | 7621352 | 58170398 | 58170421 | 17 | - | 27260156 | LNCAPCLONEFGC | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.18664872915878444 | [293] | [331,272,318,291] | 3 | hSpCas9 | negative selection | 7621353 | 58169832 | 58169855 | 17 | + | 27260156 | LNCAPCLONEFGC | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.11256079905911509 | [272] | [322,212,221,154] | -2 | hSpCas9 | negative selection | 7685607 | 58170056 | 58170079 | 17 | + | 27260156 | LNCAPCLONEFGC | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.1167321159870851 | [482] | [431,458,513,499] | 1 | hSpCas9 | negative selection | 7685608 | 58170305 | 58170328 | 17 | - | 27260156 | LNCAPCLONEFGC | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.48760017598554883 | [479] | [274,221,358,397] | -6 | hSpCas9 | negative selection | 7685609 | 58169670 | 58169693 | 17 | - | 27260156 | PANC0327 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.5220953681595196 | [692] | [1160,708,813,896] | 7 | hSpCas9 | negative selection | 7742602 | 58170567 | 58170590 | 17 | - | 27260156 | PANC0327 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.17257522392646107 | [239] | [352,173,289,161] | 2 | hSpCas9 | negative selection | 7742603 | 58170398 | 58170421 | 17 | - | 27260156 | PANC0327 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.12788960210953482 | [293] | [193,339,353,238] | 1 | hSpCas9 | negative selection | 7742604 | 58169832 | 58169855 | 17 | + | 27260156 | PANC0327 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.6899086875909745 | [272] | [64,206,171,142] | -7 | hSpCas9 | negative selection | 7806858 | 58170056 | 58170079 | 17 | + | 27260156 | PANC0327 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.21534611876306492 | [482] | [457,724,536,239] | 3 | hSpCas9 | negative selection | 7806859 | 58170305 | 58170328 | 17 | - | 27260156 | PANC0327 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.32425252676637334 | [479] | [273,377,408,290] | -5 | hSpCas9 | negative selection | 7806860 | 58169670 | 58169693 | 17 | - | 27260156 | NCIH2009 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.39433197162910205 | [692] | [1317,1412,1090] | 5 | hSpCas9 | negative selection | 7863853 | 58170567 | 58170590 | 17 | - | 27260156 | NCIH2009 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.5435316380729388 | [239] | [646,304,547] | 7 | hSpCas9 | negative selection | 7863854 | 58170398 | 58170421 | 17 | - | 27260156 | NCIH2009 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | -0.3032945265472127 | [293] | [431,314,270] | -4 | hSpCas9 | negative selection | 7863855 | 58169832 | 58169855 | 17 | + | 27260156 | NCIH2009 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | 0.06417491776623552 | [272] | [433,321,447] | 0 | hSpCas9 | negative selection | 7928109 | 58170056 | 58170079 | 17 | + | 27260156 | NCIH2009 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.18837527098391157 | [482] | [771,611,924] | 2 | hSpCas9 | negative selection | 7928110 | 58170305 | 58170328 | 17 | - | 27260156 | NCIH2009 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.29441235289925 | [479] | [482,434,710] | -4 | hSpCas9 | negative selection | 7928111 | 58169670 | 58169693 | 17 | - | 27260156 | NCIH1373 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.05756646092866646 | [692] | [1091,710,879,153] | 0 | hSpCas9 | negative selection | 7985104 | 58170567 | 58170590 | 17 | - | 27260156 | NCIH1373 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.0538463762367597 | [239] | [221,465,175,57] | 0 | hSpCas9 | negative selection | 7985105 | 58170398 | 58170421 | 17 | - | 27260156 | NCIH1373 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | -0.18889857236527063 | [293] | [179,232,483,62] | -2 | hSpCas9 | negative selection | 7985106 | 58169832 | 58169855 | 17 | + | 27260156 | NCIH1373 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.18271357626969686 | [272] | [386,300,139,69] | -2 | hSpCas9 | negative selection | 8049360 | 58170056 | 58170079 | 17 | + | 27260156 | NCIH1373 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.48883314824009766 | [482] | [422,438,271,107] | -5 | hSpCas9 | negative selection | 8049361 | 58170305 | 58170328 | 17 | - | 27260156 | NCIH1373 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.13365781348407593 | [479] | [741,198,518,150] | -1 | hSpCas9 | negative selection | 8049362 | 58169670 | 58169693 | 17 | - | 27260156 | PATU8902 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | -0.030985302077223276 | [692] | [640,1100,946,1104] | 0 | hSpCas9 | negative selection | 8106355 | 58170567 | 58170590 | 17 | - | 27260156 | PATU8902 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.6602660386796901 | [239] | [281,823,509,497] | 7 | hSpCas9 | negative selection | 8106356 | 58170398 | 58170421 | 17 | - | 27260156 | PATU8902 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.0045993152541971005 | [293] | [500,298,325,550] | 0 | hSpCas9 | negative selection | 8106357 | 58169832 | 58169855 | 17 | + | 27260156 | PATU8902 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | 0.13913400760299133 | [272] | [306,381,359,668] | 1 | hSpCas9 | negative selection | 8170611 | 58170056 | 58170079 | 17 | + | 27260156 | PATU8902 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.538387886213807 | [482] | [1251,439,1181,965] | 5 | hSpCas9 | negative selection | 8170612 | 58170305 | 58170328 | 17 | - | 27260156 | PATU8902 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.24106985903769976 | [479] | [460,737,403,716] | -2 | hSpCas9 | negative selection | 8170613 | 58169670 | 58169693 | 17 | - | 27260156 | PANC1 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.3934319692393202 | [692] | [767,967,742,688] | 6 | hSpCas9 | negative selection | 8227606 | 58170567 | 58170590 | 17 | - | 27260156 | PANC1 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.5527397412227821 | [239] | [217,278,433,275] | 8 | hSpCas9 | negative selection | 8227607 | 58170398 | 58170421 | 17 | - | 27260156 | PANC1 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.12929190672053414 | [293] | [197,350,388,193] | 2 | hSpCas9 | negative selection | 8227608 | 58169832 | 58169855 | 17 | + | 27260156 | PANC1 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.3439648390151745 | [272] | [202,168,233,134] | -5 | hSpCas9 | negative selection | 8291862 | 58170056 | 58170079 | 17 | + | 27260156 | PANC1 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.07978414485442091 | [482] | [422,514,530,314] | 1 | hSpCas9 | negative selection | 8291863 | 58170305 | 58170328 | 17 | - | 27260156 | PANC1 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.31321107937764303 | [479] | [398,367,255,307] | -5 | hSpCas9 | negative selection | 8291864 | 58169670 | 58169693 | 17 | - | 27260156 | PANC0813 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.17501461019594944 | [692] | [1259,842,837,772] | 3 | hSpCas9 | negative selection | 8348857 | 58170567 | 58170590 | 17 | - | 27260156 | PANC0813 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.6014382637216374 | [239] | [507,498,352,360] | 8 | hSpCas9 | negative selection | 8348858 | 58170398 | 58170421 | 17 | - | 27260156 | PANC0813 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.15967624892666588 | [293] | [434,383,311,413] | 2 | hSpCas9 | negative selection | 8348859 | 58169832 | 58169855 | 17 | + | 27260156 | PANC0813 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.1292742229446756 | [272] | [334,272,307,261] | -2 | hSpCas9 | negative selection | 8413113 | 58170056 | 58170079 | 17 | + | 27260156 | PANC0813 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.02924635414119732 | [482] | [564,563,626,558] | 0 | hSpCas9 | negative selection | 8413114 | 58170305 | 58170328 | 17 | - | 27260156 | PANC0813 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.42043117868650615 | [479] | [433,425,428,397] | -6 | hSpCas9 | negative selection | 8413115 | 58169670 | 58169693 | 17 | - | 27260156 | RDES | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.441280451913833 | [692] | [905,948,1269,1254] | 7 | hSpCas9 | negative selection | 8470108 | 58170567 | 58170590 | 17 | - | 27260156 | RDES | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.5597837034552727 | [239] | [375,475,346,412] | 8 | hSpCas9 | negative selection | 8470109 | 58170398 | 58170421 | 17 | - | 27260156 | RDES | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.13002833061870567 | [293] | [316,322,409,447] | 2 | hSpCas9 | negative selection | 8470110 | 58169832 | 58169855 | 17 | + | 27260156 | RDES | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.26446573751222846 | [272] | [230,241,316,256] | -4 | hSpCas9 | negative selection | 8534364 | 58170056 | 58170079 | 17 | + | 27260156 | RDES | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.03931973206574717 | [482] | [345,580,611,815] | 0 | hSpCas9 | negative selection | 8534365 | 58170305 | 58170328 | 17 | - | 27260156 | RDES | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.3866877469825866 | [479] | [279,446,500,490] | -6 | hSpCas9 | negative selection | 8534366 | 58169670 | 58169693 | 17 | - | 27260156 | PC3 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.4579747327802116 | [692] | [645,876,1755,864] | 8 | hSpCas9 | negative selection | 8591359 | 58170567 | 58170590 | 17 | - | 27260156 | PC3 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.5623595213714772 | [239] | [225,386,440,413] | 9 | hSpCas9 | negative selection | 8591360 | 58170398 | 58170421 | 17 | - | 27260156 | PC3 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.3724553050604506 | [293] | [191,333,792,415] | 7 | hSpCas9 | negative selection | 8591361 | 58169832 | 58169855 | 17 | + | 27260156 | PC3 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.5210353669886271 | [272] | [135,102,361,234] | -8 | hSpCas9 | negative selection | 8655615 | 58170056 | 58170079 | 17 | + | 27260156 | PC3 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.22289235923261147 | [482] | [392,324,424,468] | -5 | hSpCas9 | negative selection | 8655616 | 58170305 | 58170328 | 17 | - | 27260156 | PC3 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.3904034056124436 | [479] | [287,354,610,288] | -7 | hSpCas9 | negative selection | 8655617 | 58169670 | 58169693 | 17 | - | 27260156 | PATU8988T | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.4593507401886717 | [692] | [783,1020,881,1012] | 7 | hSpCas9 | negative selection | 8712610 | 58170567 | 58170590 | 17 | - | 27260156 | PATU8988T | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.9075463340764999 | [239] | [535,300,261,647] | 9 | hSpCas9 | negative selection | 8712611 | 58170398 | 58170421 | 17 | - | 27260156 | PATU8988T | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.4897431439480608 | [293] | [372,482,389,353] | 7 | hSpCas9 | negative selection | 8712612 | 58169832 | 58169855 | 17 | + | 27260156 | PATU8988T | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | 0.060338751263593116 | [272] | [288,289,198,328] | 1 | hSpCas9 | negative selection | 8776866 | 58170056 | 58170079 | 17 | + | 27260156 | PATU8988T | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.21979135025057706 | [482] | [317,548,335,415] | -4 | hSpCas9 | negative selection | 8776867 | 58170305 | 58170328 | 17 | - | 27260156 | PATU8988T | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.05944088281260475 | [479] | [454,557,406,364] | -1 | hSpCas9 | negative selection | 8776868 | 58169670 | 58169693 | 17 | - | 27260156 | T47D | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.2530394564969539 | [692] | [999,829,1048,979] | 5 | hSpCas9 | negative selection | 8833861 | 58170567 | 58170590 | 17 | - | 27260156 | T47D | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.4400376119698999 | [239] | [384,318,467,347] | 8 | hSpCas9 | negative selection | 8833862 | 58170398 | 58170421 | 17 | - | 27260156 | T47D | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.3353760710709382 | [293] | [408,422,354,546] | 7 | hSpCas9 | negative selection | 8833863 | 58169832 | 58169855 | 17 | + | 27260156 | T47D | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | 0.13514939615173993 | [272] | [248,354,412,378] | 3 | hSpCas9 | negative selection | 8898117 | 58170056 | 58170079 | 17 | + | 27260156 | T47D | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.15601999525703153 | [482] | [484,456,511,571] | -3 | hSpCas9 | negative selection | 8898118 | 58170305 | 58170328 | 17 | - | 27260156 | T47D | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.39152067387684863 | [479] | [452,416,372,464] | -7 | hSpCas9 | negative selection | 8898119 | 58169670 | 58169693 | 17 | - | 27260156 | SU8686 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.2522109142868568 | [692] | [609,667,932,1157] | 4 | hSpCas9 | negative selection | 8955112 | 58170567 | 58170590 | 17 | - | 27260156 | SU8686 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.6006274683947217 | [239] | [306,381,356,404] | 8 | hSpCas9 | negative selection | 8955113 | 58170398 | 58170421 | 17 | - | 27260156 | SU8686 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.36067995147806203 | [293] | [305,403,298,508] | 6 | hSpCas9 | negative selection | 8955114 | 58169832 | 58169855 | 17 | + | 27260156 | SU8686 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.12060006289361414 | [272] | [256,195,257,296] | -2 | hSpCas9 | negative selection | 9019368 | 58170056 | 58170079 | 17 | + | 27260156 | SU8686 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.03870324763301456 | [482] | [474,504,397,476] | 0 | hSpCas9 | negative selection | 9019369 | 58170305 | 58170328 | 17 | - | 27260156 | SU8686 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.12413403749726365 | [479] | [355,436,375,609] | -2 | hSpCas9 | negative selection | 9019370 | 58169670 | 58169693 | 17 | - | 27260156 | SKES1 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.3277823315786149 | [692] | [903,920,792,856] | 7 | hSpCas9 | negative selection | 9076363 | 58170567 | 58170590 | 17 | - | 27260156 | SKES1 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.5750722092088947 | [239] | [377,451,400,221] | 9 | hSpCas9 | negative selection | 9076364 | 58170398 | 58170421 | 17 | - | 27260156 | SKES1 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.573106398700729 | [293] | [501,459,514,291] | 9 | hSpCas9 | negative selection | 9076365 | 58169832 | 58169855 | 17 | + | 27260156 | SKES1 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.4717141894867284 | [272] | [221,224,198,149] | -8 | hSpCas9 | negative selection | 9140619 | 58170056 | 58170079 | 17 | + | 27260156 | SKES1 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.16339863041372302 | [482] | [651,419,398,291] | -4 | hSpCas9 | negative selection | 9140620 | 58170305 | 58170328 | 17 | - | 27260156 | SKES1 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.47571560359226156 | [479] | [372,275,448,277] | -8 | hSpCas9 | negative selection | 9140621 | 58169670 | 58169693 | 17 | - | 27260156 | TOV112D | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.3232889453674914 | [692] | [807,760,905,962] | 6 | hSpCas9 | negative selection | 9197614 | 58170567 | 58170590 | 17 | - | 27260156 | TOV112D | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.3254659517844656 | [239] | [290,365,282,279] | 6 | hSpCas9 | negative selection | 9197615 | 58170398 | 58170421 | 17 | - | 27260156 | TOV112D | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.5971816939286887 | [293] | [641,419,344,385] | 9 | hSpCas9 | negative selection | 9197616 | 58169832 | 58169855 | 17 | + | 27260156 | TOV112D | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.35573580734708254 | [272] | [210,288,207,165] | -6 | hSpCas9 | negative selection | 9261870 | 58170056 | 58170079 | 17 | + | 27260156 | TOV112D | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.288031968456825 | [482] | [622,651,570,534] | 5 | hSpCas9 | negative selection | 9261871 | 58170305 | 58170328 | 17 | - | 27260156 | TOV112D | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.8391748843623533 | [479] | [245,365,307,178] | -9 | hSpCas9 | negative selection | 9261872 | 58169670 | 58169693 | 17 | - | 27260156 | TC71 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.3081382191372929 | [692] | [1106,924,807,832] | 7 | hSpCas9 | negative selection | 9318865 | 58170567 | 58170590 | 17 | - | 27260156 | TC71 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.5683273044846417 | [239] | [306,298,509,408] | 9 | hSpCas9 | negative selection | 9318866 | 58170398 | 58170421 | 17 | - | 27260156 | TC71 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.32472637583007197 | [293] | [406,355,366,452] | 7 | hSpCas9 | negative selection | 9318867 | 58169832 | 58169855 | 17 | + | 27260156 | TC71 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | -0.24005670783745126 | [272] | [142,255,266,331] | -6 | hSpCas9 | negative selection | 9383121 | 58170056 | 58170079 | 17 | + | 27260156 | TC71 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | -0.12499562592013101 | [482] | [609,491,343,452] | -3 | hSpCas9 | negative selection | 9383122 | 58170305 | 58170328 | 17 | - | 27260156 | TC71 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.38588365700494165 | [479] | [345,358,389,486] | -8 | hSpCas9 | negative selection | 9383123 | 58169670 | 58169693 | 17 | - | 27260156 | TC32 | viability | CAAAGTCTGATACCCACGTGAGG | OR4D2 | ENSG00000255713 | 0.26872524823540456 | [692] | [759,699,865,812] | 5 | hSpCas9 | negative selection | 9440116 | 58170567 | 58170590 | 17 | - | 27260156 | TC32 | viability | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.7299231592906601 | [239] | [184,315,665,406] | 9 | hSpCas9 | negative selection | 9440117 | 58170398 | 58170421 | 17 | - | 27260156 | TC32 | viability | AATGCTTGGAACGAAGATCATGG | OR4D2 | ENSG00000255713 | 0.5420360119483905 | [293] | [350,441,419,360] | 8 | hSpCas9 | negative selection | 9440118 | 58169832 | 58169855 | 17 | + | 27260156 | TC32 | viability | GTACTTTCTGCTCCGAAACCTGG | OR4D2 | ENSG00000255713 | 0.04005007475485367 | [272] | [261,194,333,287] | 0 | hSpCas9 | negative selection | 9504372 | 58170056 | 58170079 | 17 | + | 27260156 | TC32 | viability | CCGTCATGAACACTCAGCTCTGG | OR4D2 | ENSG00000255713 | 0.20438925933076085 | [482] | [490,380,733,550] | 3 | hSpCas9 | negative selection | 9504373 | 58170305 | 58170328 | 17 | - | 27260156 | TC32 | viability | CATCACCAGGATGAATAAGTAGG | OR4D2 | ENSG00000255713 | -0.6535826937758061 | [479] | [179,229,425,357] | -8 | hSpCas9 | negative selection | 9504374 | 58169657 | 58169680 | 17 | + | 27869803 | HPAFII | viability after 27 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.1168136649827502 | [191] | [163,33,NaN] | -1 | hSpCas9 | negative selection | 9562033 | 58170445 | 58170468 | 17 | - | 27869803 | HPAFII | viability after 27 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 0.5461513477396795 | [269] | [197,214,NaN] | 4 | hSpCas9 | negative selection | 9562034 | 58170548 | 58170571 | 17 | + | 27869803 | HPAFII | viability after 27 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | 0.3909167883967739 | [246] | [310,52,NaN] | 3 | hSpCas9 | negative selection | 9562035 | 58170567 | 58170590 | 17 | - | 27869803 | HPAFII | viability after 27 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -0.5203859777681392 | [93] | [40,28,NaN] | -4 | hSpCas9 | negative selection | 9562036 | 58169657 | 58169680 | 17 | + | 27869803 | HPAFII | viability after 15 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.2458175109789968 | [191] | [395,35,NaN] | -3 | hSpCas9 | negative selection | 9644482 | 58170445 | 58170468 | 17 | - | 27869803 | HPAFII | viability after 15 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 0.5631227201317052 | [269] | [527,366,NaN] | 6 | hSpCas9 | negative selection | 9644483 | 58170548 | 58170571 | 17 | + | 27869803 | HPAFII | viability after 15 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | 0.08728214535190768 | [246] | [429,189,NaN] | 1 | hSpCas9 | negative selection | 9644484 | 58170567 | 58170590 | 17 | - | 27869803 | HPAFII | viability after 15 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -1.287583131758889 | [93] | [41,40,NaN] | -8 | hSpCas9 | negative selection | 9644485 | 58169657 | 58169680 | 17 | + | 27869803 | ASPC1 | viability after 36 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | 0.04591555084300958 | [467] | [140,299,81] | 0 | hSpCas9 | negative selection | 9726931 | 58170445 | 58170468 | 17 | - | 27869803 | ASPC1 | viability after 36 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 0.45376050290096986 | [665] | [422,380,191] | 4 | hSpCas9 | negative selection | 9726932 | 58170548 | 58170571 | 17 | + | 27869803 | ASPC1 | viability after 36 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | 0.49327842743728845 | [538] | [351,459,45] | 5 | hSpCas9 | negative selection | 9726933 | 58170567 | 58170590 | 17 | - | 27869803 | ASPC1 | viability after 36 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.28437106562861136 | [262] | [189,74,84] | 3 | hSpCas9 | negative selection | 9726934 | 58169657 | 58169680 | 17 | + | 27869803 | PATU8988S | viability after 35 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | 0.14757501202829348 | [454] | [197,207,NaN] | 1 | hSpCas9 | negative selection | 9809380 | 58170445 | 58170468 | 17 | - | 27869803 | PATU8988S | viability after 35 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | -0.05335171057964516 | [684] | [207,323,NaN] | 0 | hSpCas9 | negative selection | 9809381 | 58170548 | 58170571 | 17 | + | 27869803 | PATU8988S | viability after 35 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | 0.1922113833423893 | [416] | [139,243,NaN] | 2 | hSpCas9 | negative selection | 9809382 | 58170567 | 58170590 | 17 | - | 27869803 | PATU8988S | viability after 35 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.4751508380376135 | [255] | [64,221,NaN] | 5 | hSpCas9 | negative selection | 9809383 | 58169657 | 58169680 | 17 | + | 27869803 | PATU8988S | viability after 31 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | -0.04480940422133578 | [454] | [174,176,NaN] | 0 | hSpCas9 | negative selection | 9891829 | 58170445 | 58170468 | 17 | - | 27869803 | PATU8988S | viability after 31 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | -0.2877600799326093 | [684] | [166,295,NaN] | -3 | hSpCas9 | negative selection | 9891830 | 58170548 | 58170571 | 17 | + | 27869803 | PATU8988S | viability after 31 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | 0.048695227486459935 | [416] | [94,269,NaN] | 0 | hSpCas9 | negative selection | 9891831 | 58170567 | 58170590 | 17 | - | 27869803 | PATU8988S | viability after 31 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | 0.28337833285260583 | [255] | [92,163,NaN] | 3 | hSpCas9 | negative selection | 9891832 | 58169657 | 58169680 | 17 | + | 27869803 | HPAFII | viability after 35 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | 0.2709470300842185 | [191] | [208,13,NaN] | 1 | hSpCas9 | negative selection | 9974278 | 58170445 | 58170468 | 17 | - | 27869803 | HPAFII | viability after 35 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 0.44127055214388017 | [269] | [194,174,NaN] | 3 | hSpCas9 | negative selection | 9974279 | 58170548 | 58170571 | 17 | + | 27869803 | HPAFII | viability after 35 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | 0.8332397215067763 | [246] | [266,172,NaN] | 5 | hSpCas9 | negative selection | 9974280 | 58170567 | 58170590 | 17 | - | 27869803 | HPAFII | viability after 35 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -1.2299073281647026 | [93] | [8,32,NaN] | -6 | hSpCas9 | negative selection | 9974281 | 58169657 | 58169680 | 17 | + | 27869803 | HPAFII | viability after 31 days | TGGAAACAGGGAACCTCACGTGG | OR4D2 | ENSG00000255713 | 0.29965648935361733 | [191] | [235,19,NaN] | 2 | hSpCas9 | negative selection | 10056727 | 58170445 | 58170468 | 17 | - | 27869803 | HPAFII | viability after 31 days | ACAAGCTTGTCCATAGGGAATGG | OR4D2 | ENSG00000255713 | 0.5121108645965718 | [269] | [128,310,NaN] | 4 | hSpCas9 | negative selection | 10056728 | 58170548 | 58170571 | 17 | + | 27869803 | HPAFII | viability after 31 days | TGAGAAGATTAGGGAGACACCGG | OR4D2 | ENSG00000255713 | 0.7431182109168651 | [246] | [332,121,NaN] | 5 | hSpCas9 | negative selection | 10056729 | 58170567 | 58170590 | 17 | - | 27869803 | HPAFII | viability after 31 days | ATTGTCACTCTCAAACCAGCCGG | OR4D2 | ENSG00000255713 | -1.513436330262605 | [93] | [17,18,NaN] | -7 | hSpCas9 | negative selection | 10056730 |