| 20060451 | 20060474 | 14 | + | 26627737 | DLD1 | viability | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.4178480130221821 | [877] | [376,323,392] | 4 | hSpCas9 | negative selection | 787812 | 20060588 | 20060611 | 14 | - | 26627737 | DLD1 | viability | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.29835960266239603 | [1025] | [292,529,369] | 3 | hSpCas9 | negative selection | 787813 | 20060589 | 20060612 | 14 | - | 26627737 | DLD1 | viability | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | -0.16497097998929466 | [1096] | [319,465,160] | -2 | hSpCas9 | negative selection | 787814 | 20060590 | 20060613 | 14 | - | 26627737 | DLD1 | viability | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.7476260286719554 | [1249] | [469,682,794] | 7 | hSpCas9 | negative selection | 787815 | 20060451 | 20060474 | 14 | + | 26627737 | GBM cells | viability after 5 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | -0.2896339779038404 | [652] | [307,264] | -4 | hSpCas9 | negative selection | 870127 | 20060588 | 20060611 | 14 | - | 26627737 | GBM cells | viability after 5 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.15410041889679427 | [552] | [385,273] | 2 | hSpCas9 | negative selection | 870128 | 20060589 | 20060612 | 14 | - | 26627737 | GBM cells | viability after 5 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.5871174815081887 | [336] | [243,298] | 8 | hSpCas9 | negative selection | 870129 | 20060590 | 20060613 | 14 | - | 26627737 | GBM cells | viability after 5 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.05283928046176434 | [674] | [344,405] | 0 | hSpCas9 | negative selection | 870130 | 20060451 | 20060474 | 14 | + | 26627737 | GBM cells | viability after 13 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | -0.31994829714045436 | [652] | [290,277] | -4 | hSpCas9 | negative selection | 952442 | 20060588 | 20060611 | 14 | - | 26627737 | GBM cells | viability after 13 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.07081518062437886 | [552] | [393,250] | 0 | hSpCas9 | negative selection | 952443 | 20060589 | 20060612 | 14 | - | 26627737 | GBM cells | viability after 13 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.8254793029394428 | [336] | [312,332] | 8 | hSpCas9 | negative selection | 952444 | 20060590 | 20060613 | 14 | - | 26627737 | GBM cells | viability after 13 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.0005077299573046368 | [674] | [340,386] | 0 | hSpCas9 | negative selection | 952445 | 20060451 | 20060474 | 14 | + | 26627737 | GBM cells | viability after 21 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | -0.2484208079689707 | [652] | [306,290] | -2 | hSpCas9 | negative selection | 1034757 | 20060588 | 20060611 | 14 | - | 26627737 | GBM cells | viability after 21 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.21158042107730912 | [552] | [373,323] | 2 | hSpCas9 | negative selection | 1034758 | 20060589 | 20060612 | 14 | - | 26627737 | GBM cells | viability after 21 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.662099724668762 | [336] | [319,261] | 6 | hSpCas9 | negative selection | 1034759 | 20060590 | 20060613 | 14 | - | 26627737 | GBM cells | viability after 21 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | -0.4885177134902774 | [674] | [275,247] | -4 | hSpCas9 | negative selection | 1034760 | 20060451 | 20060474 | 14 | + | 26627737 | RPE1 | viability after 9 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.754646430220241 | [1348] | [619,831] | 5 | hSpCas9 | negative selection | 1117072 | 20060588 | 20060611 | 14 | - | 26627737 | RPE1 | viability after 9 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 1.787846664139718 | [537] | [471,722] | 8 | hSpCas9 | negative selection | 1117073 | 20060589 | 20060612 | 14 | - | 26627737 | RPE1 | viability after 9 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.3322972113384841 | [1905] | [604,939] | 2 | hSpCas9 | negative selection | 1117074 | 20060590 | 20060613 | 14 | - | 26627737 | RPE1 | viability after 9 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.8521249170792298 | [2257] | [1410,1101] | 5 | hSpCas9 | negative selection | 1117075 | 20060451 | 20060474 | 14 | + | 26627737 | RPE1 | viability after 12 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.9377037099411244 | [1348] | [786,595] | 6 | hSpCas9 | negative selection | 1199387 | 20060588 | 20060611 | 14 | - | 26627737 | RPE1 | viability after 12 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 1.6615109455171488 | [537] | [414,501] | 8 | hSpCas9 | negative selection | 1199388 | 20060589 | 20060612 | 14 | - | 26627737 | RPE1 | viability after 12 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.5913280681879074 | [1905] | [703,842] | 4 | hSpCas9 | negative selection | 1199389 | 20060590 | 20060613 | 14 | - | 26627737 | RPE1 | viability after 12 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 1.0271781458750544 | [2257] | [1435,1024] | 6 | hSpCas9 | negative selection | 1199390 | 20060451 | 20060474 | 14 | + | 26627737 | RPE1 | viability after 15 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.7795648610534741 | [1348] | [763,549] | 5 | hSpCas9 | negative selection | 1281702 | 20060588 | 20060611 | 14 | - | 26627737 | RPE1 | viability after 15 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 1.7217650435631713 | [537] | [446,554] | 8 | hSpCas9 | negative selection | 1281703 | 20060589 | 20060612 | 14 | - | 26627737 | RPE1 | viability after 15 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.4625865464405938 | [1905] | [659,822] | 3 | hSpCas9 | negative selection | 1281704 | 20060590 | 20060613 | 14 | - | 26627737 | RPE1 | viability after 15 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 1.101107982182962 | [2257] | [1807,947] | 6 | hSpCas9 | negative selection | 1281705 | 20060451 | 20060474 | 14 | + | 26627737 | RPE1 | viability after 18 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.39814331233992284 | [1348] | [355,611] | 2 | hSpCas9 | negative selection | 1364017 | 20060588 | 20060611 | 14 | - | 26627737 | RPE1 | viability after 18 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 1.6084269833796077 | [537] | [375,513] | 8 | hSpCas9 | negative selection | 1364018 | 20060589 | 20060612 | 14 | - | 26627737 | RPE1 | viability after 18 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.5851727871421921 | [1905] | [761,781] | 3 | hSpCas9 | negative selection | 1364019 | 20060590 | 20060613 | 14 | - | 26627737 | RPE1 | viability after 18 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 1.2537186500781696 | [2257] | [1789,1092] | 7 | hSpCas9 | negative selection | 1364020 | 20060451 | 20060474 | 14 | + | 26627737 | HeLa | viability after 8 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.39349507081030777 | [943] | [536,657,430] | 3 | hSpCas9 | negative selection | 1446332 | 20060588 | 20060611 | 14 | - | 26627737 | HeLa | viability after 8 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | -0.15227985045515435 | [896] | [675,258,200] | -1 | hSpCas9 | negative selection | 1446333 | 20060589 | 20060612 | 14 | - | 26627737 | HeLa | viability after 8 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.7857293830839946 | [532] | [386,636,187] | 6 | hSpCas9 | negative selection | 1446334 | 20060590 | 20060613 | 14 | - | 26627737 | HeLa | viability after 8 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.1486994588748496 | [1324] | [947,480,561] | 1 | hSpCas9 | negative selection | 1446335 | 20060451 | 20060474 | 14 | + | 26627737 | HeLa | viability after 12 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.38050488302309793 | [943] | [737,349,458] | 3 | hSpCas9 | negative selection | 1528647 | 20060588 | 20060611 | 14 | - | 26627737 | HeLa | viability after 12 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.18046606913517516 | [896] | [398,416,443] | 1 | hSpCas9 | negative selection | 1528648 | 20060589 | 20060612 | 14 | - | 26627737 | HeLa | viability after 12 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.4554490954958897 | [532] | [254,393,245] | 4 | hSpCas9 | negative selection | 1528649 | 20060590 | 20060613 | 14 | - | 26627737 | HeLa | viability after 12 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | -0.22320924918482588 | [1324] | [473,604,313] | -2 | hSpCas9 | negative selection | 1528650 | 20060451 | 20060474 | 14 | + | 26627737 | HeLa | viability after 15 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.08488955420685174 | [943] | [375,441,404] | 0 | hSpCas9 | negative selection | 1610962 | 20060588 | 20060611 | 14 | - | 26627737 | HeLa | viability after 15 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.4197320650360923 | [896] | [414,615,430] | 3 | hSpCas9 | negative selection | 1610963 | 20060589 | 20060612 | 14 | - | 26627737 | HeLa | viability after 15 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.592803947202633 | [532] | [343,340,293] | 5 | hSpCas9 | negative selection | 1610964 | 20060590 | 20060613 | 14 | - | 26627737 | HeLa | viability after 15 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | -0.4705254727945838 | [1324] | [543,194,429] | -4 | hSpCas9 | negative selection | 1610965 | 20060451 | 20060474 | 14 | + | 26627737 | HeLa | viability after 18 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.08184080943943184 | [943] | [248,367,404] | 0 | hSpCas9 | negative selection | 1693277 | 20060588 | 20060611 | 14 | - | 26627737 | HeLa | viability after 18 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.39445525259522474 | [896] | [253,519,430] | 3 | hSpCas9 | negative selection | 1693278 | 20060589 | 20060612 | 14 | - | 26627737 | HeLa | viability after 18 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.6002676960638436 | [532] | [231,284,293] | 5 | hSpCas9 | negative selection | 1693279 | 20060590 | 20060613 | 14 | - | 26627737 | HeLa | viability after 18 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | -0.5169483274883264 | [1324] | [346,153,429] | -4 | hSpCas9 | negative selection | 1693280 | 20060451 | 20060474 | 14 | + | 26627737 | HCT116 | viability after 6 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.7466693577579135 | [1331] | [351,350] | 4 | hSpCas9 | negative selection | 1775592 | 20060588 | 20060611 | 14 | - | 26627737 | HCT116 | viability after 6 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | -0.37129003308273845 | [881] | [277,12] | -2 | hSpCas9 | negative selection | 1775593 | 20060589 | 20060612 | 14 | - | 26627737 | HCT116 | viability after 6 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.7230669018769085 | [720] | [257,147] | 4 | hSpCas9 | negative selection | 1775594 | 20060590 | 20060613 | 14 | - | 26627737 | HCT116 | viability after 6 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | -0.15864526366657639 | [1082] | [332,52] | -1 | hSpCas9 | negative selection | 1775595 | 20060451 | 20060474 | 14 | + | 26627737 | HCT116 | viability after 8 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.3414965737238149 | [790] | [546,498,609] | 3 | hSpCas9 | negative selection | 1857907 | 20060588 | 20060611 | 14 | - | 26627737 | HCT116 | viability after 8 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.2681350442647328 | [495] | [391,306,289] | 3 | hSpCas9 | negative selection | 1857908 | 20060589 | 20060612 | 14 | - | 26627737 | HCT116 | viability after 8 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | -0.35601267254058044 | [703] | [312,255,339] | -4 | hSpCas9 | negative selection | 1857909 | 20060590 | 20060613 | 14 | - | 26627737 | HCT116 | viability after 8 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | -0.27030632363630436 | [891] | [182,495,537] | -3 | hSpCas9 | negative selection | 1857910 | 20060451 | 20060474 | 14 | + | 26627737 | HCT116 | viability after 9 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.24168161213233486 | [1331] | [424,416] | 1 | hSpCas9 | negative selection | 1940222 | 20060588 | 20060611 | 14 | - | 26627737 | HCT116 | viability after 9 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.4031720825956031 | [881] | [435,212] | 3 | hSpCas9 | negative selection | 1940223 | 20060589 | 20060612 | 14 | - | 26627737 | HCT116 | viability after 9 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.6241400314016332 | [720] | [222,354] | 4 | hSpCas9 | negative selection | 1940224 | 20060590 | 20060613 | 14 | - | 26627737 | HCT116 | viability after 9 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.06481322663365874 | [1082] | [235,354] | 0 | hSpCas9 | negative selection | 1940225 | 20060451 | 20060474 | 14 | + | 26627737 | HCT116 | viability after 12 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.2027040163281577 | [790] | [319,679,453] | 2 | hSpCas9 | negative selection | 2022537 | 20060588 | 20060611 | 14 | - | 26627737 | HCT116 | viability after 12 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.6900644272835189 | [495] | [428,466,365] | 6 | hSpCas9 | negative selection | 2022538 | 20060589 | 20060612 | 14 | - | 26627737 | HCT116 | viability after 12 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | -0.5341805973062312 | [703] | [125,303,348] | -5 | hSpCas9 | negative selection | 2022539 | 20060590 | 20060613 | 14 | - | 26627737 | HCT116 | viability after 12 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | -0.2923383836491251 | [891] | [439,368,333] | -3 | hSpCas9 | negative selection | 2022540 | 20060451 | 20060474 | 14 | + | 26627737 | HCT116 | viability after 15 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.5331144437799515 | [790] | [763,727,494] | 5 | hSpCas9 | negative selection | 2104852 | 20060588 | 20060611 | 14 | - | 26627737 | HCT116 | viability after 15 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.23761129700120542 | [495] | [397,354,262] | 2 | hSpCas9 | negative selection | 2104853 | 20060589 | 20060612 | 14 | - | 26627737 | HCT116 | viability after 15 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | -0.10124828562431576 | [703] | [226,220,660] | -1 | hSpCas9 | negative selection | 2104854 | 20060590 | 20060613 | 14 | - | 26627737 | HCT116 | viability after 15 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | -0.2934122596734321 | [891] | [390,299,557] | -3 | hSpCas9 | negative selection | 2104855 | 20060451 | 20060474 | 14 | + | 26627737 | HCT116 | viability after 18 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.36431430419039557 | [790] | [302,670,490] | 3 | hSpCas9 | negative selection | 2187167 | 20060588 | 20060611 | 14 | - | 26627737 | HCT116 | viability after 18 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.34254790046606753 | [495] | [349,337,217] | 3 | hSpCas9 | negative selection | 2187168 | 20060589 | 20060612 | 14 | - | 26627737 | HCT116 | viability after 18 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | -0.29246360738847 | [703] | [191,164,493] | -3 | hSpCas9 | negative selection | 2187169 | 20060590 | 20060613 | 14 | - | 26627737 | HCT116 | viability after 18 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.1390600059354652 | [891] | [515,411,501] | 1 | hSpCas9 | negative selection | 2187170 | 20060451 | 20060474 | 14 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | ATGAGCCACAAGCTGCTAAAGGG | OR4L1 | ENSG00000176246 | -0.6310638841761831 | [2,2] | [2,0] | -7 | hSpCas9 | positive selection | 3008208 | 20060429 | 20060452 | 14 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | ATGATTGTCCTATAGTGCAGGGG | OR4L1 | ENSG00000176246 | -0.34636421622658264 | [3,3] | [4,0] | -5 | hSpCas9 | positive selection | 3008209 | 20060430 | 20060453 | 14 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CATGATTGTCCTATAGTGCAGGG | OR4L1 | ENSG00000176246 | 0.2688872350040631 | [3,3] | [4,3] | 6 | hSpCas9 | positive selection | 3008210 | 20060216 | 20060239 | 14 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TTTCCAAGGAGAAAGTACAAGGG | OR4L1 | ENSG00000176246 | 0.13995577585811342 | [4,4] | [4,3] | 3 | hSpCas9 | positive selection | 3008211 | 20060451 | 20060474 | 14 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | ATGAGCCACAAGCTGCTAAAGGG | OR4L1 | ENSG00000176246 | -0.28760182668295986 | [2,2] | [2,0] | -4 | hSpCas9 | positive selection | 3076066 | 20060429 | 20060452 | 14 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | ATGATTGTCCTATAGTGCAGGGG | OR4L1 | ENSG00000176246 | 0.5262195122093135 | [3,3] | [2,3] | 8 | hSpCas9 | positive selection | 3076067 | 20060430 | 20060453 | 14 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CATGATTGTCCTATAGTGCAGGG | OR4L1 | ENSG00000176246 | -0.06486416123967324 | [3,3] | [3,1] | -1 | hSpCas9 | positive selection | 3076068 | 20060216 | 20060239 | 14 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TTTCCAAGGAGAAAGTACAAGGG | OR4L1 | ENSG00000176246 | 0.5373060260344525 | [4,4] | [4,4] | 8 | hSpCas9 | positive selection | 3076069 | 20060449 | 20060472 | | + | 24336571 | A375 | resistance to PLX after 7 days | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.050664061176291186 | [12,11] | [9,13] | -1 | hSpCas9 | positive selection | 3132910 | 20060477 | 20060500 | | + | 24336571 | A375 | resistance to PLX after 7 days | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | -0.24352110609228414 | [17,17] | [12,15] | -7 | hSpCas9 | positive selection | 3132911 | 20060449 | 20060472 | | + | 24336571 | A375 | resistance to PLX after 14 days | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.07975246871231528 | [15,9] | [4,5] | -1 | hSpCas9 | positive selection | 3190703 | 20060477 | 20060500 | | + | 24336571 | A375 | resistance to PLX after 14 days | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | -0.8401434129297166 | [21,16] | [4,3] | -8 | hSpCas9 | positive selection | 3190704 | 20060449 | 20060472 | | + | 24336571 | A375 | viability after 7 days | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.019519052333386355 | [12] | [12,11] | 0 | hSpCas9 | negative selection | 3248496 | 20060477 | 20060500 | | + | 24336571 | A375 | viability after 7 days | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.5533283015466409 | [12] | [17,17] | 8 | hSpCas9 | negative selection | 3248497 | 20060449 | 20060472 | | + | 24336571 | A375 | viability after 14 days | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.054866661220672734 | [12] | [15,9] | 0 | hSpCas9 | negative selection | 3306289 | 20060477 | 20060500 | | + | 24336571 | A375 | viability after 14 days | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.7247273038334919 | [12] | [21,16] | 8 | hSpCas9 | negative selection | 3306290 | 20060883 | 20060906 | 14 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 1.3504356158373165 | [59,59] | [0,0] | 6 | hSpCas9 | positive selection | 3383589 | 20060449 | 20060472 | 14 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.13838513872232763 | [138,138] | [0,0] | 0 | hSpCas9 | positive selection | 3383590 | 20060455 | 20060478 | 14 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 1.9302548132825132 | [280,280] | [6,6] | 7 | hSpCas9 | positive selection | 3383591 | 20060450 | 20060473 | 14 | + | 26780180 | HT29 | viability (Avana library 4 designs) | ATGAGCCACAAGCTGCTAAAGGG | OR4L1 | ENSG00000176246 | 0.831882874522412 | [] | [] | 3 | hSpCas9 | negative selection | 3446186 | 20060429 | 20060452 | 14 | - | 26780180 | HT29 | viability (Avana library 4 designs) | ATGATTGTCCTATAGTGCAGGGG | OR4L1 | ENSG00000176246 | 0.594708763579858 | [] | [] | 2 | hSpCas9 | negative selection | 3446187 | 20060430 | 20060453 | 14 | - | 26780180 | HT29 | viability (Avana library 4 designs) | CATGATTGTCCTATAGTGCAGGG | OR4L1 | ENSG00000176246 | 0.367367354237656 | [] | [] | 1 | hSpCas9 | negative selection | 3446188 | 20060216 | 20060239 | 14 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TTTCCAAGGAGAAAGTACAAGGG | OR4L1 | ENSG00000176246 | -0.392605188350945 | [] | [] | -6 | hSpCas9 | negative selection | 3446189 | 20060429 | 20060452 | 14 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ATGATTGTCCTATAGTGCAGGGG | OR4L1 | ENSG00000176246 | 1.48038621183614 | [] | [] | 2 | hSpCas9 | negative selection | 3539382 | 20060216 | 20060239 | 14 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TTTCCAAGGAGAAAGTACAAGGG | OR4L1 | ENSG00000176246 | -6.43601429427376 | [] | [] | -6 | hSpCas9 | negative selection | 3539383 | 20060430 | 20060453 | 14 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CATGATTGTCCTATAGTGCAGGG | OR4L1 | ENSG00000176246 | 4.06055100059432 | [] | [] | 6 | hSpCas9 | negative selection | 3539384 | 20060450 | 20060473 | 14 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ATGAGCCACAAGCTGCTAAAGGG | OR4L1 | ENSG00000176246 | -4.63557780809979 | [] | [] | -5 | hSpCas9 | negative selection | 3539385 | 20060213 | 20060236 | 14 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TCTCCCTTGTACTTTCTCCTTGG | OR4L1 | ENSG00000176246 | -6.89671002168536 | [] | [] | -6 | hSpCas9 | negative selection | 3539386 | 20060205 | 20060228 | 14 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AAAGTACAAGGGAGAATGAAGGG | OR4L1 | ENSG00000176246 | -1.33044780663166 | [] | [] | -2 | hSpCas9 | negative selection | 3539387 | 20060429 | 20060452 | 14 | - | 26780180 | A375 | viability (Avana lentiGuide) | ATGATTGTCCTATAGTGCAGGGG | OR4L1 | ENSG00000176246 | -0.318960304193708 | [] | [] | 0 | hSpCas9 | negative selection | 3648041 | 20060216 | 20060239 | 14 | - | 26780180 | A375 | viability (Avana lentiGuide) | TTTCCAAGGAGAAAGTACAAGGG | OR4L1 | ENSG00000176246 | -4.97766893126235 | [] | [] | -8 | hSpCas9 | negative selection | 3648042 | 20060430 | 20060453 | 14 | - | 26780180 | A375 | viability (Avana lentiGuide) | CATGATTGTCCTATAGTGCAGGG | OR4L1 | ENSG00000176246 | -3.88176346887905 | [] | [] | -6 | hSpCas9 | negative selection | 3648043 | 20060450 | 20060473 | 14 | + | 26780180 | A375 | viability (Avana lentiGuide) | ATGAGCCACAAGCTGCTAAAGGG | OR4L1 | ENSG00000176246 | -7.19218274823507 | [] | [] | -9 | hSpCas9 | negative selection | 3648044 | 20060213 | 20060236 | 14 | + | 26780180 | A375 | viability (Avana lentiGuide) | TCTCCCTTGTACTTTCTCCTTGG | OR4L1 | ENSG00000176246 | -5.8861469587278 | [] | [] | -8 | hSpCas9 | negative selection | 3648045 | 20060205 | 20060228 | 14 | - | 26780180 | A375 | viability (Avana lentiGuide) | AAAGTACAAGGGAGAATGAAGGG | OR4L1 | ENSG00000176246 | -8.73100061217558 | [] | [] | -9 | hSpCas9 | negative selection | 3648046 | 20060429 | 20060452 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ATGATTGTCCTATAGTGCAGGGG | OR4L1 | ENSG00000176246 | -0.19186146101841353 | [6] | [4,4] | -3 | hSpCas9 | positive selection | 3756700 | 20060216 | 20060239 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TTTCCAAGGAGAAAGTACAAGGG | OR4L1 | ENSG00000176246 | -0.2858842551193018 | [7] | [6,5] | -4 | hSpCas9 | positive selection | 3756701 | 20060430 | 20060453 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CATGATTGTCCTATAGTGCAGGG | OR4L1 | ENSG00000176246 | 0.13303445971326505 | [5] | [6,5] | 3 | hSpCas9 | positive selection | 3756702 | 20060450 | 20060473 | 14 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ATGAGCCACAAGCTGCTAAAGGG | OR4L1 | ENSG00000176246 | 0.0628092787919227 | [4] | [5,4] | 1 | hSpCas9 | positive selection | 3756703 | 20060213 | 20060236 | 14 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TCTCCCTTGTACTTTCTCCTTGG | OR4L1 | ENSG00000176246 | 0.06309344575898157 | [0] | [0,0] | 1 | hSpCas9 | positive selection | 3756704 | 20060205 | 20060228 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AAAGTACAAGGGAGAATGAAGGG | OR4L1 | ENSG00000176246 | -0.2498783303694111 | [6] | [5,4] | -4 | hSpCas9 | positive selection | 3756705 | 20060429 | 20060452 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ATGATTGTCCTATAGTGCAGGGG | OR4L1 | ENSG00000176246 | 0.04721422522107054 | [5] | [4,5] | 1 | hSpCas9 | positive selection | 3865307 | 20060216 | 20060239 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TTTCCAAGGAGAAAGTACAAGGG | OR4L1 | ENSG00000176246 | 0.11353229512515714 | [6] | [5,5] | 2 | hSpCas9 | positive selection | 3865308 | 20060430 | 20060453 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CATGATTGTCCTATAGTGCAGGG | OR4L1 | ENSG00000176246 | 0.11502729155936015 | [6] | [5,5] | 2 | hSpCas9 | positive selection | 3865309 | 20060450 | 20060473 | 14 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ATGAGCCACAAGCTGCTAAAGGG | OR4L1 | ENSG00000176246 | 0.34432753137945327 | [4] | [5,4] | 8 | hSpCas9 | positive selection | 3865310 | 20060213 | 20060236 | 14 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TCTCCCTTGTACTTTCTCCTTGG | OR4L1 | ENSG00000176246 | -0.2356556194752089 | [3] | [2,2] | -3 | hSpCas9 | positive selection | 3865311 | 20060205 | 20060228 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AAAGTACAAGGGAGAATGAAGGG | OR4L1 | ENSG00000176246 | 0.24970003420351555 | [4] | [5,3] | 6 | hSpCas9 | positive selection | 3865312 | 20060883 | 20060906 | 14 | - | 26780180 | A375 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 1.63522385395006 | [] | [] | 8 | hSpCas9 | negative selection | 3976234 | 20060455 | 20060478 | 14 | - | 26780180 | A375 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.451653983752787 | [] | [] | 1 | hSpCas9 | negative selection | 3976235 | 20060449 | 20060472 | 14 | + | 26780180 | A375 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 1.04166935456827 | [] | [] | 5 | hSpCas9 | negative selection | 3976236 | 20060477 | 20060500 | 14 | + | 26780180 | A375 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.991049475060168 | [] | [] | 4 | hSpCas9 | negative selection | 3976237 | 20060140 | 20060163 | 14 | - | 26780180 | A375 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 1.40624292473721 | [] | [] | 7 | hSpCas9 | negative selection | 3976238 | 20060608 | 20060631 | 14 | + | 26780180 | A375 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.867190477806055 | [] | [] | 3 | hSpCas9 | negative selection | 3976239 | 20060883 | 20060906 | 14 | - | 26780180 | HT29 | viability (GeCKOv2 library) | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 1.7034056176011 | [] | [] | 8 | hSpCas9 | negative selection | 4084200 | 20060455 | 20060478 | 14 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | -0.162411775477937 | [] | [] | -5 | hSpCas9 | negative selection | 4084201 | 20060449 | 20060472 | 14 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.8572742791516 | [] | [] | 3 | hSpCas9 | negative selection | 4084202 | 20060477 | 20060500 | 14 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.278020033803903 | [] | [] | 0 | hSpCas9 | negative selection | 4084203 | 20060140 | 20060163 | 14 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 2.61791496258744 | [] | [] | 9 | hSpCas9 | negative selection | 4084204 | 20060608 | 20060631 | 14 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 1.6117891983309 | [] | [] | 8 | hSpCas9 | negative selection | 4084205 | 20060449 | 20060472 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.48102063114188975 | [3] | [4,2] | 9 | hSpCas9 | positive selection | 4157716 | 20060477 | 20060500 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | -0.04578312249411193 | [3] | [2,2] | -1 | hSpCas9 | positive selection | 4157717 | 20060449 | 20060472 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.0754021452157664 | [3] | [3,2,0,0] | 0 | hSpCas9 | positive selection | 4221738 | 20060477 | 20060500 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 1.1158582839210238 | [3] | [2,0,4,3] | 8 | hSpCas9 | positive selection | 4221739 | 20060140 | 20060163 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | -0.25701234179386667 | [4] | [2,1] | -5 | hSpCas9 | positive selection | 4287687 | 20060477 | 20060500 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.33968834353800137 | [3] | [3,2] | 7 | hSpCas9 | positive selection | 4287688 | 20060608 | 20060631 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | -0.020464290367110893 | [3] | [2,2] | 0 | hSpCas9 | positive selection | 4287689 | 20060883 | 20060906 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.6485483798672436 | [2] | [1,0] | -9 | hSpCas9 | positive selection | 4351943 | 20060449 | 20060472 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.09279815381918692 | [2] | [2,1] | -2 | hSpCas9 | positive selection | 4351944 | 20060455 | 20060478 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.13551215822291318 | [3] | [3,2] | 2 | hSpCas9 | positive selection | 4351945 | 20060477 | 20060500 | 14 | + | 27661255 | K562 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.09082960554041286 | [1273,1197] | [1104,1007] | 3 | dCas9-KRAB | negative selection | 5499017 | 20060140 | 20060163 | 14 | - | 27260156 | BXPC3 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.14001815696107967 | [1027] | [1247,1311,895,1262] | 3 | hSpCas9 | negative selection | 5560147 | 20060477 | 20060500 | 14 | + | 27260156 | BXPC3 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.4626766852522624 | [628] | [1043,781,841,946] | 8 | hSpCas9 | negative selection | 5560148 | 20060608 | 20060631 | 14 | + | 27260156 | BXPC3 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.10646134297205034 | [930] | [1100,924,948,1231] | 2 | hSpCas9 | negative selection | 5560149 | 20060883 | 20060906 | 14 | - | 27260156 | BXPC3 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.31364376394170124 | [274] | [167,286,187,290] | -6 | hSpCas9 | negative selection | 5624403 | 20060449 | 20060472 | 14 | + | 27260156 | BXPC3 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.21814640285198886 | [453] | [485,292,352,506] | -5 | hSpCas9 | negative selection | 5624404 | 20060455 | 20060478 | 14 | - | 27260156 | BXPC3 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.05962612117195465 | [581] | [577,568,636,775] | 1 | hSpCas9 | negative selection | 5624405 | 20060140 | 20060163 | 14 | - | 27260156 | A673 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.12116077315212137 | [1027] | [1383,1291,1241,1462] | 3 | hSpCas9 | negative selection | 5681398 | 20060477 | 20060500 | 14 | + | 27260156 | A673 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.43775615100683934 | [628] | [1115,910,1057,1017] | 8 | hSpCas9 | negative selection | 5681399 | 20060608 | 20060631 | 14 | + | 27260156 | A673 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | -0.008120330153241206 | [930] | [1285,953,1107,1120] | 0 | hSpCas9 | negative selection | 5681400 | 20060883 | 20060906 | 14 | - | 27260156 | A673 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.5603300423644454 | [274] | [308,216,153,225] | -8 | hSpCas9 | negative selection | 5745654 | 20060449 | 20060472 | 14 | + | 27260156 | A673 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.2782076912740773 | [453] | [546,320,455,489] | -6 | hSpCas9 | negative selection | 5745655 | 20060455 | 20060478 | 14 | - | 27260156 | A673 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.3161381688656015 | [581] | [960,768,866,895] | 7 | hSpCas9 | negative selection | 5745656 | 20060140 | 20060163 | 14 | - | 27260156 | A375 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.31825535967668683 | [1027] | [1623,1825,1395,1216] | 4 | hSpCas9 | negative selection | 5802649 | 20060477 | 20060500 | 14 | + | 27260156 | A375 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.6579165263047257 | [628] | [1147,1620,802,1127] | 8 | hSpCas9 | negative selection | 5802650 | 20060608 | 20060631 | 14 | + | 27260156 | A375 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.24858323260150772 | [930] | [1402,1678,1091,1069] | 3 | hSpCas9 | negative selection | 5802651 | 20060883 | 20060906 | 14 | - | 27260156 | A375 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.06937500275642239 | [274] | [367,337,112,397] | -1 | hSpCas9 | negative selection | 5866905 | 20060449 | 20060472 | 14 | + | 27260156 | A375 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.11598998435924282 | [453] | [601,698,503,515] | 1 | hSpCas9 | negative selection | 5866906 | 20060455 | 20060478 | 14 | - | 27260156 | A375 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.14603928126062798 | [581] | [745,791,699,770] | 2 | hSpCas9 | negative selection | 5866907 | 20060140 | 20060163 | 14 | - | 27260156 | COLO741 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.2024347271745761 | [1027] | [1740,1399,1415] | 4 | hSpCas9 | negative selection | 5923900 | 20060477 | 20060500 | 14 | + | 27260156 | COLO741 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.26747013056729846 | [628] | [954,1227,733] | 5 | hSpCas9 | negative selection | 5923901 | 20060608 | 20060631 | 14 | + | 27260156 | COLO741 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.12919016389955795 | [930] | [1350,1249,1302] | 2 | hSpCas9 | negative selection | 5923902 | 20060883 | 20060906 | 14 | - | 27260156 | COLO741 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.6398163334734118 | [274] | [288,176,215] | -8 | hSpCas9 | negative selection | 5988156 | 20060449 | 20060472 | 14 | + | 27260156 | COLO741 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.05310050004354463 | [453] | [613,442,618] | -1 | hSpCas9 | negative selection | 5988157 | 20060455 | 20060478 | 14 | - | 27260156 | COLO741 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.418832212962954 | [581] | [1092,952,945] | 8 | hSpCas9 | negative selection | 5988158 | 20060140 | 20060163 | 14 | - | 27260156 | CAL120 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.22829034735858977 | [1027] | [1144,1695,1598] | 3 | hSpCas9 | negative selection | 6045151 | 20060477 | 20060500 | 14 | + | 27260156 | CAL120 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.5155991110660907 | [628] | [1259,1073,1044] | 7 | hSpCas9 | negative selection | 6045152 | 20060608 | 20060631 | 14 | + | 27260156 | CAL120 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.11473238185442247 | [930] | [1039,1576,1115] | 1 | hSpCas9 | negative selection | 6045153 | 20060883 | 20060906 | 14 | - | 27260156 | CAL120 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 0.4224302710077619 | [274] | [263,713,369] | 6 | hSpCas9 | negative selection | 6109407 | 20060449 | 20060472 | 14 | + | 27260156 | CAL120 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.07918858909894505 | [453] | [350,455,939] | 1 | hSpCas9 | negative selection | 6109408 | 20060455 | 20060478 | 14 | - | 27260156 | CAL120 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.3915040148473275 | [581] | [1085,882,901] | 6 | hSpCas9 | negative selection | 6109409 | 20060140 | 20060163 | 14 | - | 27260156 | CADOES1 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.15982824604915513 | [1027] | [1201,994,954,1121] | 2 | hSpCas9 | negative selection | 6166402 | 20060477 | 20060500 | 14 | + | 27260156 | CADOES1 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.7948115623107022 | [628] | [884,1008,714,1467] | 9 | hSpCas9 | negative selection | 6166403 | 20060608 | 20060631 | 14 | + | 27260156 | CADOES1 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.08257596197163142 | [930] | [891,1103,730,941] | 1 | hSpCas9 | negative selection | 6166404 | 20060883 | 20060906 | 14 | - | 27260156 | CADOES1 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 0.3116418949721925 | [274] | [302,313,303,349] | 5 | hSpCas9 | negative selection | 6230658 | 20060449 | 20060472 | 14 | + | 27260156 | CADOES1 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.0719219827467992 | [453] | [284,400,445,477] | -1 | hSpCas9 | negative selection | 6230659 | 20060455 | 20060478 | 14 | - | 27260156 | CADOES1 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.03160130331895111 | [581] | [518,799,513,373] | 0 | hSpCas9 | negative selection | 6230660 | 20060140 | 20060163 | 14 | - | 27260156 | EWS502 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.25338902431429244 | [1027] | [960,1629,1168,1463] | 4 | hSpCas9 | negative selection | 6287653 | 20060477 | 20060500 | 14 | + | 27260156 | EWS502 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.4490582942540777 | [628] | [855,1003,922,849] | 7 | hSpCas9 | negative selection | 6287654 | 20060608 | 20060631 | 14 | + | 27260156 | EWS502 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.07058137340412152 | [930] | [965,988,1001,1202] | 1 | hSpCas9 | negative selection | 6287655 | 20060883 | 20060906 | 14 | - | 27260156 | EWS502 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.8631253808146832 | [274] | [179,162,133,159] | -8 | hSpCas9 | negative selection | 6351909 | 20060449 | 20060472 | 14 | + | 27260156 | EWS502 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.1624116618035332 | [453] | [324,591,348,457] | -3 | hSpCas9 | negative selection | 6351910 | 20060455 | 20060478 | 14 | - | 27260156 | EWS502 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.17470939605315894 | [581] | [573,706,699,822] | 3 | hSpCas9 | negative selection | 6351911 | 20060140 | 20060163 | 14 | - | 27260156 | EW8 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.22035787932976936 | [1027] | [1067,869,848,1122] | 4 | hSpCas9 | negative selection | 6408904 | 20060477 | 20060500 | 14 | + | 27260156 | EW8 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 1.0119127194871538 | [628] | [830,759,1594,803] | 9 | hSpCas9 | negative selection | 6408905 | 20060608 | 20060631 | 14 | + | 27260156 | EW8 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | -0.11291131932038445 | [930] | [712,792,644,648] | -2 | hSpCas9 | negative selection | 6408906 | 20060883 | 20060906 | 14 | - | 27260156 | EW8 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.38664336326765303 | [274] | [197,182,89,226] | -6 | hSpCas9 | negative selection | 6473160 | 20060449 | 20060472 | 14 | + | 27260156 | EW8 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.15314296200648192 | [453] | [411,222,329,365] | -3 | hSpCas9 | negative selection | 6473161 | 20060455 | 20060478 | 14 | - | 27260156 | EW8 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | -0.11472545307810098 | [581] | [461,512,325,461] | -2 | hSpCas9 | negative selection | 6473162 | 20060140 | 20060163 | 14 | - | 27260156 | CORL105 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.07871756588856416 | [1027] | [1398,1086,1388,1234] | 1 | hSpCas9 | negative selection | 6530155 | 20060477 | 20060500 | 14 | + | 27260156 | CORL105 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.6303211620598872 | [628] | [1030,1135,1428,1004] | 9 | hSpCas9 | negative selection | 6530156 | 20060608 | 20060631 | 14 | + | 27260156 | CORL105 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.3049256424631669 | [930] | [1728,1136,1232,1285] | 5 | hSpCas9 | negative selection | 6530157 | 20060883 | 20060906 | 14 | - | 27260156 | CORL105 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 0.09373351897270266 | [274] | [364,387,335,283] | 1 | hSpCas9 | negative selection | 6594411 | 20060449 | 20060472 | 14 | + | 27260156 | CORL105 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.3351501408282339 | [453] | [451,523,316,374] | -6 | hSpCas9 | negative selection | 6594412 | 20060455 | 20060478 | 14 | - | 27260156 | CORL105 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.2765774869347302 | [581] | [685,899,909,811] | 5 | hSpCas9 | negative selection | 6594413 | 20060140 | 20060163 | 14 | - | 27260156 | HS294T | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.3675060188534509 | [1027] | [549,435,421,665] | 5 | hSpCas9 | negative selection | 6651406 | 20060477 | 20060500 | 14 | + | 27260156 | HS294T | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.5948213881939124 | [628] | [268,459,414,322] | 7 | hSpCas9 | negative selection | 6651407 | 20060608 | 20060631 | 14 | + | 27260156 | HS294T | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.6057877002604465 | [930] | [541,474,429,784] | 7 | hSpCas9 | negative selection | 6651408 | 20060883 | 20060906 | 14 | - | 27260156 | HS294T | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.2378068690648082 | [274] | [54,78,60,184] | -3 | hSpCas9 | negative selection | 6715662 | 20060449 | 20060472 | 14 | + | 27260156 | HS294T | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.3421714982245276 | [453] | [115,163,119,157] | -5 | hSpCas9 | negative selection | 6715663 | 20060455 | 20060478 | 14 | - | 27260156 | HS294T | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | -0.08060102952201278 | [581] | [182,210,188,281] | -1 | hSpCas9 | negative selection | 6715664 | 20060140 | 20060163 | 14 | - | 27260156 | HCC44 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.20713298384211698 | [1027] | [1166,1073,2068,1199] | 3 | hSpCas9 | negative selection | 6772657 | 20060477 | 20060500 | 14 | + | 27260156 | HCC44 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.5978467868920267 | [628] | [1172,1117,1029,974] | 8 | hSpCas9 | negative selection | 6772658 | 20060608 | 20060631 | 14 | + | 27260156 | HCC44 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.08700467306723925 | [930] | [1134,947,1455,1012] | 1 | hSpCas9 | negative selection | 6772659 | 20060883 | 20060906 | 14 | - | 27260156 | HCC44 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 0.15910362828815028 | [274] | [264,205,816,196] | 2 | hSpCas9 | negative selection | 6836913 | 20060449 | 20060472 | 14 | + | 27260156 | HCC44 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.031838245250029984 | [453] | [533,390,490,687] | 0 | hSpCas9 | negative selection | 6836914 | 20060455 | 20060478 | 14 | - | 27260156 | HCC44 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.164601349349912 | [581] | [767,702,769,717] | 2 | hSpCas9 | negative selection | 6836915 | 20060140 | 20060163 | 14 | - | 27260156 | G402 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.22904357454250412 | [1027] | [1511,1477,1409,1480] | 3 | hSpCas9 | negative selection | 6893908 | 20060477 | 20060500 | 14 | + | 27260156 | G402 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.6194132878783536 | [628] | [1587,1289,820,1082] | 7 | hSpCas9 | negative selection | 6893909 | 20060608 | 20060631 | 14 | + | 27260156 | G402 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.2501820310819981 | [930] | [854,2221,1051,1253] | 3 | hSpCas9 | negative selection | 6893910 | 20060883 | 20060906 | 14 | - | 27260156 | G402 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 0.10426941202689421 | [274] | [304,482,217,430] | 1 | hSpCas9 | negative selection | 6958164 | 20060449 | 20060472 | 14 | + | 27260156 | G402 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.3618751436739507 | [453] | [584,955,720,584] | 4 | hSpCas9 | negative selection | 6958165 | 20060455 | 20060478 | 14 | - | 27260156 | G402 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.3705150559621047 | [581] | [1110,967,583,1030] | 4 | hSpCas9 | negative selection | 6958166 | 20060140 | 20060163 | 14 | - | 27260156 | L33 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | -0.0016026249810920934 | [1027] | [1023,375,680,1081] | 0 | hSpCas9 | negative selection | 7015159 | 20060477 | 20060500 | 14 | + | 27260156 | L33 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.6128080222220538 | [628] | [1121,433,592,720] | 9 | hSpCas9 | negative selection | 7015160 | 20060608 | 20060631 | 14 | + | 27260156 | L33 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.19200313198206376 | [930] | [1099,492,605,985] | 4 | hSpCas9 | negative selection | 7015161 | 20060883 | 20060906 | 14 | - | 27260156 | L33 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.1882844515197224 | [274] | [251,125,122,209] | -4 | hSpCas9 | negative selection | 7079415 | 20060449 | 20060472 | 14 | + | 27260156 | L33 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.3183219786888968 | [453] | [372,168,205,342] | -6 | hSpCas9 | negative selection | 7079416 | 20060455 | 20060478 | 14 | - | 27260156 | L33 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.024249668057471807 | [581] | [584,271,400,481] | 0 | hSpCas9 | negative selection | 7079417 | 20060140 | 20060163 | 14 | - | 27260156 | K562 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | -0.008395584869334005 | [1027] | [1213,677,1213,570] | 0 | hSpCas9 | negative selection | 7136410 | 20060477 | 20060500 | 14 | + | 27260156 | K562 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.4362181966019231 | [628] | [697,992,648,692] | 5 | hSpCas9 | negative selection | 7136411 | 20060608 | 20060631 | 14 | + | 27260156 | K562 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.5671386891822555 | [930] | [1157,1554,1125,1080] | 7 | hSpCas9 | negative selection | 7136412 | 20060883 | 20060906 | 14 | - | 27260156 | K562 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.1320860279571111 | [274] | [184,130,211,339] | -2 | hSpCas9 | negative selection | 7200666 | 20060449 | 20060472 | 14 | + | 27260156 | K562 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.09820506080436162 | [453] | [483,779,164,328] | 1 | hSpCas9 | negative selection | 7200667 | 20060455 | 20060478 | 14 | - | 27260156 | K562 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | -0.24314848997924232 | [581] | [325,495,396,509] | -3 | hSpCas9 | negative selection | 7200668 | 20060140 | 20060163 | 14 | - | 27260156 | HT29 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | -0.0026937471850891903 | [1027] | [1471,1143,1209,1171] | 0 | hSpCas9 | negative selection | 7257661 | 20060477 | 20060500 | 14 | + | 27260156 | HT29 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.4576526352240959 | [628] | [1277,1198,1064,721] | 8 | hSpCas9 | negative selection | 7257662 | 20060608 | 20060631 | 14 | + | 27260156 | HT29 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.15046177089240131 | [930] | [1504,1163,1427,965] | 3 | hSpCas9 | negative selection | 7257663 | 20060883 | 20060906 | 14 | - | 27260156 | HT29 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.03643487048202443 | [274] | [299,288,324,375] | 0 | hSpCas9 | negative selection | 7321917 | 20060449 | 20060472 | 14 | + | 27260156 | HT29 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.1092677347997856 | [453] | [581,385,562,506] | -2 | hSpCas9 | negative selection | 7321918 | 20060455 | 20060478 | 14 | - | 27260156 | HT29 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.22557765400588853 | [581] | [918,896,870,650] | 4 | hSpCas9 | negative selection | 7321919 | 20060140 | 20060163 | 14 | - | 27260156 | MHHES1 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.23534144347964414 | [1027] | [1465,1462,1517,1066] | 4 | hSpCas9 | negative selection | 7378912 | 20060477 | 20060500 | 14 | + | 27260156 | MHHES1 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.7222106752501638 | [628] | [1375,1452,997,929] | 9 | hSpCas9 | negative selection | 7378913 | 20060608 | 20060631 | 14 | + | 27260156 | MHHES1 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.13016509341844007 | [930] | [1547,1257,985,890] | 2 | hSpCas9 | negative selection | 7378914 | 20060883 | 20060906 | 14 | - | 27260156 | MHHES1 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.30627600419387313 | [274] | [291,168,331,209] | -5 | hSpCas9 | negative selection | 7443168 | 20060449 | 20060472 | 14 | + | 27260156 | MHHES1 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.42773491035599337 | [453] | [397,489,305,339] | -7 | hSpCas9 | negative selection | 7443169 | 20060455 | 20060478 | 14 | - | 27260156 | MHHES1 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | -0.17676674236104736 | [581] | [774,526,631,426] | -3 | hSpCas9 | negative selection | 7443170 | 20060140 | 20060163 | 14 | - | 27260156 | MEWO | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.0419963692372427 | [1027] | [1053,916,1011] | 0 | hSpCas9 | negative selection | 7500163 | 20060477 | 20060500 | 14 | + | 27260156 | MEWO | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.39278272750619775 | [628] | [1016,570,777] | 7 | hSpCas9 | negative selection | 7500164 | 20060608 | 20060631 | 14 | + | 27260156 | MEWO | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.2733438760410031 | [930] | [1451,896,886] | 6 | hSpCas9 | negative selection | 7500165 | 20060883 | 20060906 | 14 | - | 27260156 | MEWO | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.15405905415997212 | [274] | [238,255,199] | -3 | hSpCas9 | negative selection | 7564419 | 20060449 | 20060472 | 14 | + | 27260156 | MEWO | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.3272937734083152 | [453] | [371,340,308] | -6 | hSpCas9 | negative selection | 7564420 | 20060455 | 20060478 | 14 | - | 27260156 | MEWO | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.2733306889927782 | [581] | [780,636,579] | 6 | hSpCas9 | negative selection | 7564421 | 20060140 | 20060163 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.2513363442193859 | [1027] | [1070,1180,1236,958] | 4 | hSpCas9 | negative selection | 7621414 | 20060477 | 20060500 | 14 | + | 27260156 | LNCAPCLONEFGC | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.44129933817705963 | [628] | [632,820,707,921] | 7 | hSpCas9 | negative selection | 7621415 | 20060608 | 20060631 | 14 | + | 27260156 | LNCAPCLONEFGC | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.23847930133491502 | [930] | [1031,894,1048,1016] | 4 | hSpCas9 | negative selection | 7621416 | 20060883 | 20060906 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.784445420748313 | [274] | [256,94,120,102] | -8 | hSpCas9 | negative selection | 7685670 | 20060449 | 20060472 | 14 | + | 27260156 | LNCAPCLONEFGC | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.14706727422440344 | [453] | [384,460,547,441] | 2 | hSpCas9 | negative selection | 7685671 | 20060455 | 20060478 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.32605370646908843 | [581] | [498,555,901,731] | 5 | hSpCas9 | negative selection | 7685672 | 20060140 | 20060163 | 14 | - | 27260156 | PANC0327 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.12483565140617969 | [1027] | [899,1000,1002,1069] | 1 | hSpCas9 | negative selection | 7742665 | 20060477 | 20060500 | 14 | + | 27260156 | PANC0327 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.33003881969872045 | [628] | [970,457,777,655] | 5 | hSpCas9 | negative selection | 7742666 | 20060608 | 20060631 | 14 | + | 27260156 | PANC0327 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.19426009634336594 | [930] | [686,1140,871,1037] | 3 | hSpCas9 | negative selection | 7742667 | 20060883 | 20060906 | 14 | - | 27260156 | PANC0327 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.07405862557621357 | [274] | [222,139,129,445] | -1 | hSpCas9 | negative selection | 7806921 | 20060449 | 20060472 | 14 | + | 27260156 | PANC0327 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.056565654895674077 | [453] | [676,152,366,407] | -1 | hSpCas9 | negative selection | 7806922 | 20060455 | 20060478 | 14 | - | 27260156 | PANC0327 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.2601401738994242 | [581] | [673,400,641,791] | 4 | hSpCas9 | negative selection | 7806923 | 20060140 | 20060163 | 14 | - | 27260156 | NCIH2009 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.3977446943867058 | [1027] | [2206,2093,1430] | 5 | hSpCas9 | negative selection | 7863916 | 20060477 | 20060500 | 14 | + | 27260156 | NCIH2009 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.8449930489348028 | [628] | [1715,1368,1678] | 9 | hSpCas9 | negative selection | 7863917 | 20060608 | 20060631 | 14 | + | 27260156 | NCIH2009 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.266688336578632 | [930] | [1938,1392,1436] | 3 | hSpCas9 | negative selection | 7863918 | 20060883 | 20060906 | 14 | - | 27260156 | NCIH2009 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 0.027911641580841806 | [274] | [327,496,334] | 0 | hSpCas9 | negative selection | 7928172 | 20060449 | 20060472 | 14 | + | 27260156 | NCIH2009 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.22545694429690064 | [453] | [658,526,463] | -3 | hSpCas9 | negative selection | 7928173 | 20060455 | 20060478 | 14 | - | 27260156 | NCIH2009 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.12965709346865817 | [581] | [1269,751,722] | 1 | hSpCas9 | negative selection | 7928174 | 20060140 | 20060163 | 14 | - | 27260156 | NCIH1373 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.6007883044998541 | [1027] | [1553,1689,1722,526] | 6 | hSpCas9 | negative selection | 7985167 | 20060477 | 20060500 | 14 | + | 27260156 | NCIH1373 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.9545387744094589 | [628] | [1833,809,1716,318] | 8 | hSpCas9 | negative selection | 7985168 | 20060608 | 20060631 | 14 | + | 27260156 | NCIH1373 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.1860865021859529 | [930] | [1353,1060,1298,277] | 1 | hSpCas9 | negative selection | 7985169 | 20060883 | 20060906 | 14 | - | 27260156 | NCIH1373 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.2630818316571283 | [274] | [191,426,153,58] | -3 | hSpCas9 | negative selection | 8049423 | 20060449 | 20060472 | 14 | + | 27260156 | NCIH1373 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | 0.07809621205556821 | [453] | [392,486,473,207] | 0 | hSpCas9 | negative selection | 8049424 | 20060455 | 20060478 | 14 | - | 27260156 | NCIH1373 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.04941094366383725 | [581] | [678,450,947,166] | 0 | hSpCas9 | negative selection | 8049425 | 20060140 | 20060163 | 14 | - | 27260156 | PATU8902 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.405958498381334 | [1027] | [1405,2428,1720,2093] | 4 | hSpCas9 | negative selection | 8106418 | 20060477 | 20060500 | 14 | + | 27260156 | PATU8902 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.7327740803684313 | [628] | [1037,893,1708,2196] | 7 | hSpCas9 | negative selection | 8106419 | 20060608 | 20060631 | 14 | + | 27260156 | PATU8902 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.3054546191392521 | [930] | [1428,1366,1838,1714] | 3 | hSpCas9 | negative selection | 8106420 | 20060883 | 20060906 | 14 | - | 27260156 | PATU8902 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.0811224005924942 | [274] | [78,481,219,751] | -1 | hSpCas9 | negative selection | 8170674 | 20060449 | 20060472 | 14 | + | 27260156 | PATU8902 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.12783995203043907 | [453] | [733,598,395,632] | -1 | hSpCas9 | negative selection | 8170675 | 20060455 | 20060478 | 14 | - | 27260156 | PATU8902 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.38671041707433923 | [581] | [728,1164,1240,1051] | 4 | hSpCas9 | negative selection | 8170676 | 20060140 | 20060163 | 14 | - | 27260156 | PANC1 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.11141243894649988 | [1027] | [884,920,1016,968] | 1 | hSpCas9 | negative selection | 8227669 | 20060477 | 20060500 | 14 | + | 27260156 | PANC1 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.6528339437690487 | [628] | [648,1106,857,829] | 9 | hSpCas9 | negative selection | 8227670 | 20060608 | 20060631 | 14 | + | 27260156 | PANC1 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | -0.022848500683655404 | [930] | [619,943,930,692] | 0 | hSpCas9 | negative selection | 8227671 | 20060883 | 20060906 | 14 | - | 27260156 | PANC1 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.5289237864062525 | [274] | [187,231,167,89] | -7 | hSpCas9 | negative selection | 8291925 | 20060449 | 20060472 | 14 | + | 27260156 | PANC1 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.04682261263369047 | [453] | [364,517,311,342] | -1 | hSpCas9 | negative selection | 8291926 | 20060455 | 20060478 | 14 | - | 27260156 | PANC1 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | -0.1495512334084464 | [581] | [473,453,363,494] | -2 | hSpCas9 | negative selection | 8291927 | 20060140 | 20060163 | 14 | - | 27260156 | PANC0813 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.3201332744873222 | [1027] | [1764,1326,1566,1398] | 5 | hSpCas9 | negative selection | 8348920 | 20060477 | 20060500 | 14 | + | 27260156 | PANC0813 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.7140081271684748 | [628] | [1512,1176,1080,1107] | 9 | hSpCas9 | negative selection | 8348921 | 20060608 | 20060631 | 14 | + | 27260156 | PANC0813 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.4857716834827216 | [930] | [1782,1412,1455,1495] | 7 | hSpCas9 | negative selection | 8348922 | 20060883 | 20060906 | 14 | - | 27260156 | PANC0813 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 0.27195541793575684 | [274] | [378,380,312,479] | 4 | hSpCas9 | negative selection | 8413176 | 20060449 | 20060472 | 14 | + | 27260156 | PANC0813 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.2499930984240563 | [453] | [588,476,526,225] | -4 | hSpCas9 | negative selection | 8413177 | 20060455 | 20060478 | 14 | - | 27260156 | PANC0813 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.14466379256459544 | [581] | [641,613,837,908] | 2 | hSpCas9 | negative selection | 8413178 | 20060140 | 20060163 | 14 | - | 27260156 | RDES | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.26907554632332586 | [1027] | [1206,1453,1514,1542] | 4 | hSpCas9 | negative selection | 8470171 | 20060477 | 20060500 | 14 | + | 27260156 | RDES | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.6747733269361749 | [628] | [739,1323,1321,1302] | 9 | hSpCas9 | negative selection | 8470172 | 20060608 | 20060631 | 14 | + | 27260156 | RDES | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | -0.08151550743854086 | [930] | [862,899,1065,1271] | -1 | hSpCas9 | negative selection | 8470173 | 20060883 | 20060906 | 14 | - | 27260156 | RDES | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.7837488710192381 | [274] | [220,140,211,144] | -8 | hSpCas9 | negative selection | 8534427 | 20060449 | 20060472 | 14 | + | 27260156 | RDES | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.10077250795965767 | [453] | [308,519,418,760] | -2 | hSpCas9 | negative selection | 8534428 | 20060455 | 20060478 | 14 | - | 27260156 | RDES | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.1070360263043107 | [581] | [631,611,828,839] | 1 | hSpCas9 | negative selection | 8534429 | 20060140 | 20060163 | 14 | - | 27260156 | PC3 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.24548913296151076 | [1027] | [820,1155,1902,1299] | 5 | hSpCas9 | negative selection | 8591422 | 20060477 | 20060500 | 14 | + | 27260156 | PC3 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.44368279799153126 | [628] | [510,800,1357,1017] | 8 | hSpCas9 | negative selection | 8591423 | 20060608 | 20060631 | 14 | + | 27260156 | PC3 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | -0.2838425198021075 | [930] | [441,681,1457,816] | -6 | hSpCas9 | negative selection | 8591424 | 20060883 | 20060906 | 14 | - | 27260156 | PC3 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.305065177862908 | [274] | [170,234,287,213] | -6 | hSpCas9 | negative selection | 8655678 | 20060449 | 20060472 | 14 | + | 27260156 | PC3 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.30855936884403773 | [453] | [170,264,728,508] | -6 | hSpCas9 | negative selection | 8655679 | 20060455 | 20060478 | 14 | - | 27260156 | PC3 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.48571599000122895 | [581] | [558,679,1494,814] | 8 | hSpCas9 | negative selection | 8655680 | 20060140 | 20060163 | 14 | - | 27260156 | PATU8988T | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.13969035207585967 | [1027] | [1200,1370,770,1061] | 2 | hSpCas9 | negative selection | 8712673 | 20060477 | 20060500 | 14 | + | 27260156 | PATU8988T | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.6582106014946965 | [628] | [973,1284,714,890] | 9 | hSpCas9 | negative selection | 8712674 | 20060608 | 20060631 | 14 | + | 27260156 | PATU8988T | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | -0.037726996649947386 | [930] | [818,1479,692,545] | 0 | hSpCas9 | negative selection | 8712675 | 20060883 | 20060906 | 14 | - | 27260156 | PATU8988T | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.05857892943927523 | [274] | [295,227,231,262] | -1 | hSpCas9 | negative selection | 8776929 | 20060449 | 20060472 | 14 | + | 27260156 | PATU8988T | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.03459719062398254 | [453] | [772,313,324,279] | 0 | hSpCas9 | negative selection | 8776930 | 20060455 | 20060478 | 14 | - | 27260156 | PATU8988T | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.4566573972796601 | [581] | [842,913,545,802] | 7 | hSpCas9 | negative selection | 8776931 | 20060140 | 20060163 | 14 | - | 27260156 | T47D | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.20402481806435668 | [1027] | [1421,1280,1430,1391] | 4 | hSpCas9 | negative selection | 8833924 | 20060477 | 20060500 | 14 | + | 27260156 | T47D | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.31364799280951056 | [628] | [1090,772,897,892] | 6 | hSpCas9 | negative selection | 8833925 | 20060608 | 20060631 | 14 | + | 27260156 | T47D | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.20552692416907614 | [930] | [1314,1057,1251,1398] | 4 | hSpCas9 | negative selection | 8833926 | 20060883 | 20060906 | 14 | - | 27260156 | T47D | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 0.07258626959288039 | [274] | [347,367,282,346] | 1 | hSpCas9 | negative selection | 8898180 | 20060449 | 20060472 | 14 | + | 27260156 | T47D | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.13628770430558138 | [453] | [486,460,522,453] | -3 | hSpCas9 | negative selection | 8898181 | 20060455 | 20060478 | 14 | - | 27260156 | T47D | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.3442581914049136 | [581] | [843,829,818,955] | 7 | hSpCas9 | negative selection | 8898182 | 20060140 | 20060163 | 14 | - | 27260156 | SU8686 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.2811225833422262 | [1027] | [1020,1195,1421,1360] | 5 | hSpCas9 | negative selection | 8955175 | 20060477 | 20060500 | 14 | + | 27260156 | SU8686 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.6055484028600067 | [628] | [740,956,953,1199] | 8 | hSpCas9 | negative selection | 8955176 | 20060608 | 20060631 | 14 | + | 27260156 | SU8686 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.30039332455493517 | [930] | [978,859,1307,1510] | 5 | hSpCas9 | negative selection | 8955177 | 20060883 | 20060906 | 14 | - | 27260156 | SU8686 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.1348830195365458 | [274] | [273,245,187,284] | -2 | hSpCas9 | negative selection | 9019431 | 20060449 | 20060472 | 14 | + | 27260156 | SU8686 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.008575747023915753 | [453] | [298,480,528,500] | 0 | hSpCas9 | negative selection | 9019432 | 20060455 | 20060478 | 14 | - | 27260156 | SU8686 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.055050164882220365 | [581] | [523,480,722,710] | 0 | hSpCas9 | negative selection | 9019433 | 20060140 | 20060163 | 14 | - | 27260156 | SKES1 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.13737182759175237 | [1027] | [1173,1180,1002,1152] | 3 | hSpCas9 | negative selection | 9076426 | 20060477 | 20060500 | 14 | + | 27260156 | SKES1 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.3505769275546365 | [628] | [979,828,856,579] | 7 | hSpCas9 | negative selection | 9076427 | 20060608 | 20060631 | 14 | + | 27260156 | SKES1 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.1711971457346898 | [930] | [1271,934,1081,915] | 3 | hSpCas9 | negative selection | 9076428 | 20060883 | 20060906 | 14 | - | 27260156 | SKES1 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.2806170294269562 | [274] | [172,231,243,242] | -6 | hSpCas9 | negative selection | 9140682 | 20060449 | 20060472 | 14 | + | 27260156 | SKES1 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.314915840881248 | [453] | [501,361,349,268] | -6 | hSpCas9 | negative selection | 9140683 | 20060455 | 20060478 | 14 | - | 27260156 | SKES1 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.2532550690354049 | [581] | [773,788,699,538] | 5 | hSpCas9 | negative selection | 9140684 | 20060140 | 20060163 | 14 | - | 27260156 | TOV112D | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.2150262945582535 | [1027] | [1212,1598,1044,1026] | 4 | hSpCas9 | negative selection | 9197677 | 20060477 | 20060500 | 14 | + | 27260156 | TOV112D | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.4192417145628167 | [628] | [1110,1224,594,561] | 7 | hSpCas9 | negative selection | 9197678 | 20060608 | 20060631 | 14 | + | 27260156 | TOV112D | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.042513106461111394 | [930] | [1126,1315,744,758] | 0 | hSpCas9 | negative selection | 9197679 | 20060883 | 20060906 | 14 | - | 27260156 | TOV112D | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.28316523763760715 | [274] | [160,276,212,259] | -5 | hSpCas9 | negative selection | 9261933 | 20060449 | 20060472 | 14 | + | 27260156 | TOV112D | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.2994142413399977 | [453] | [379,330,433,324] | -5 | hSpCas9 | negative selection | 9261934 | 20060455 | 20060478 | 14 | - | 27260156 | TOV112D | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.30366446550321485 | [581] | [756,1057,713,441] | 6 | hSpCas9 | negative selection | 9261935 | 20060140 | 20060163 | 14 | - | 27260156 | TC71 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | -0.03908934519104856 | [1027] | [1176,1169,904,1038] | -1 | hSpCas9 | negative selection | 9318928 | 20060477 | 20060500 | 14 | + | 27260156 | TC71 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.385399571332323 | [628] | [839,767,888,1035] | 8 | hSpCas9 | negative selection | 9318929 | 20060608 | 20060631 | 14 | + | 27260156 | TC71 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.1701261763817038 | [930] | [1196,974,1077,1248] | 4 | hSpCas9 | negative selection | 9318930 | 20060883 | 20060906 | 14 | - | 27260156 | TC71 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | -0.5443922981889159 | [274] | [161,175,209,264] | -9 | hSpCas9 | negative selection | 9383184 | 20060449 | 20060472 | 14 | + | 27260156 | TC71 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.2367187217770461 | [453] | [385,496,302,473] | -6 | hSpCas9 | negative selection | 9383185 | 20060455 | 20060478 | 14 | - | 27260156 | TC71 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.015041590228396351 | [581] | [628,713,552,627] | 0 | hSpCas9 | negative selection | 9383186 | 20060140 | 20060163 | 14 | - | 27260156 | TC32 | viability | TCACAGTAGCACCGTAGATCAGG | OR4L1 | ENSG00000176246 | 0.2119317746879097 | [1027] | [1313,765,1291,1176] | 4 | hSpCas9 | negative selection | 9440179 | 20060477 | 20060500 | 14 | + | 27260156 | TC32 | viability | GCGATACTTTCATGGATAATTGG | OR4L1 | ENSG00000176246 | 0.5097800199679952 | [628] | [801,513,1091,1097] | 8 | hSpCas9 | negative selection | 9440180 | 20060608 | 20060631 | 14 | + | 27260156 | TC32 | viability | TTGCATTGAAACATACACCCTGG | OR4L1 | ENSG00000176246 | 0.26905223741697937 | [930] | [1112,844,1215,1077] | 5 | hSpCas9 | negative selection | 9440181 | 20060883 | 20060906 | 14 | - | 27260156 | TC32 | viability | ATAAATACTCGGATTCAGTAAGG | OR4L1 | ENSG00000176246 | 0.4988331983492158 | [274] | [455,343,332,288] | 8 | hSpCas9 | negative selection | 9504435 | 20060449 | 20060472 | 14 | + | 27260156 | TC32 | viability | CATGAGCCACAAGCTGCTAAAGG | OR4L1 | ENSG00000176246 | -0.16220082869887942 | [453] | [385,283,553,341] | -3 | hSpCas9 | negative selection | 9504436 | 20060455 | 20060478 | 14 | - | 27260156 | TC32 | viability | CAAACCCCTTTAGCAGCTTGTGG | OR4L1 | ENSG00000176246 | 0.36973107328995575 | [581] | [621,620,826,780] | 6 | hSpCas9 | negative selection | 9504437 | 20060451 | 20060474 | 14 | + | 27869803 | HPAFII | viability after 27 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.4726439944271834 | [720] | [597,465,NaN] | 4 | hSpCas9 | negative selection | 9550818 | 20060588 | 20060611 | 14 | - | 27869803 | HPAFII | viability after 27 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.2687390797459426 | [396] | [293,215,NaN] | 2 | hSpCas9 | negative selection | 9550819 | 20060589 | 20060612 | 14 | - | 27869803 | HPAFII | viability after 27 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.6888369508626053 | [362] | [479,163,NaN] | 5 | hSpCas9 | negative selection | 9550820 | 20060590 | 20060613 | 14 | - | 27869803 | HPAFII | viability after 27 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.9011709566158128 | [425] | [366,460,NaN] | 7 | hSpCas9 | negative selection | 9550821 | 20060451 | 20060474 | 14 | + | 27869803 | HPAFII | viability after 15 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | -0.01130155154310275 | [720] | [1123,547,NaN] | 0 | hSpCas9 | negative selection | 9633267 | 20060588 | 20060611 | 14 | - | 27869803 | HPAFII | viability after 15 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.26107767257744097 | [396] | [588,462,NaN] | 3 | hSpCas9 | negative selection | 9633268 | 20060589 | 20060612 | 14 | - | 27869803 | HPAFII | viability after 15 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.654373697184345 | [362] | [1139,286,NaN] | 7 | hSpCas9 | negative selection | 9633269 | 20060590 | 20060613 | 14 | - | 27869803 | HPAFII | viability after 15 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.8876786975852387 | [425] | [1036,728,NaN] | 8 | hSpCas9 | negative selection | 9633270 | 20060451 | 20060474 | 14 | + | 27869803 | ASPC1 | viability after 36 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | -0.07279498570378751 | [1653] | [628,320,667] | 0 | hSpCas9 | negative selection | 9715716 | 20060588 | 20060611 | 14 | - | 27869803 | ASPC1 | viability after 36 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.3662909412021499 | [900] | [665,488,151] | 3 | hSpCas9 | negative selection | 9715717 | 20060589 | 20060612 | 14 | - | 27869803 | ASPC1 | viability after 36 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | -0.031059937530361015 | [878] | [382,370,182] | 0 | hSpCas9 | negative selection | 9715718 | 20060590 | 20060613 | 14 | - | 27869803 | ASPC1 | viability after 36 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.7078601289353577 | [1347] | [621,1025,658] | 7 | hSpCas9 | negative selection | 9715719 | 20060451 | 20060474 | 14 | + | 27869803 | PATU8988S | viability after 35 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.060165092017819166 | [1389] | [435,731,NaN] | 0 | hSpCas9 | negative selection | 9798165 | 20060588 | 20060611 | 14 | - | 27869803 | PATU8988S | viability after 35 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.07834132052327958 | [793] | [393,280,NaN] | 0 | hSpCas9 | negative selection | 9798166 | 20060589 | 20060612 | 14 | - | 27869803 | PATU8988S | viability after 35 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.4231677527636173 | [702] | [442,315,NaN] | 5 | hSpCas9 | negative selection | 9798167 | 20060590 | 20060613 | 14 | - | 27869803 | PATU8988S | viability after 35 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.5693532981276228 | [1293] | [915,629,NaN] | 6 | hSpCas9 | negative selection | 9798168 | 20060451 | 20060474 | 14 | + | 27869803 | PATU8988S | viability after 31 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | -0.2118525333533834 | [1389] | [467,491,NaN] | -2 | hSpCas9 | negative selection | 9880614 | 20060588 | 20060611 | 14 | - | 27869803 | PATU8988S | viability after 31 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.2748433973106148 | [793] | [408,349,NaN] | 3 | hSpCas9 | negative selection | 9880615 | 20060589 | 20060612 | 14 | - | 27869803 | PATU8988S | viability after 31 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.3915988998115447 | [702] | [427,290,NaN] | 5 | hSpCas9 | negative selection | 9880616 | 20060590 | 20060613 | 14 | - | 27869803 | PATU8988S | viability after 31 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.608428981281691 | [1293] | [849,705,NaN] | 7 | hSpCas9 | negative selection | 9880617 | 20060451 | 20060474 | 14 | + | 27869803 | HPAFII | viability after 35 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.10024927374670156 | [720] | [458,314,NaN] | 0 | hSpCas9 | negative selection | 9963063 | 20060588 | 20060611 | 14 | - | 27869803 | HPAFII | viability after 35 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | 0.12260398225640734 | [396] | [302,123,NaN] | 0 | hSpCas9 | negative selection | 9963064 | 20060589 | 20060612 | 14 | - | 27869803 | HPAFII | viability after 35 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.47775040333121943 | [362] | [309,194,NaN] | 3 | hSpCas9 | negative selection | 9963065 | 20060590 | 20060613 | 14 | - | 27869803 | HPAFII | viability after 35 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.6713543005219094 | [425] | [310,379,NaN] | 4 | hSpCas9 | negative selection | 9963066 | 20060451 | 20060474 | 14 | + | 27869803 | HPAFII | viability after 31 days | TGAGCCACAAGCTGCTAAAGGGG | OR4L1 | ENSG00000176246 | 0.33891181752633903 | [720] | [640,370,NaN] | 2 | hSpCas9 | negative selection | 10045512 | 20060588 | 20060611 | 14 | - | 27869803 | HPAFII | viability after 31 days | CAAGCAAGCTTGATCACAAGGGG | OR4L1 | ENSG00000176246 | -0.2766782306471712 | [396] | [237,124,NaN] | -2 | hSpCas9 | negative selection | 10045513 | 20060589 | 20060612 | 14 | - | 27869803 | HPAFII | viability after 31 days | GCAAGCAAGCTTGATCACAAGGG | OR4L1 | ENSG00000176246 | 0.5171096283370129 | [362] | [325,253,NaN] | 4 | hSpCas9 | negative selection | 10045514 | 20060590 | 20060613 | 14 | - | 27869803 | HPAFII | viability after 31 days | TGCAAGCAAGCTTGATCACAAGG | OR4L1 | ENSG00000176246 | 0.9304438367137724 | [425] | [391,524,NaN] | 7 | hSpCas9 | negative selection | 10045515 |