| 48306805 | 48306828 | 11 | + | 26627737 | DLD1 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.7483451144527988 | [2219] | [434,469,346] | -6 | hSpCas9 | negative selection | 778831 | 48306977 | 48307000 | 11 | - | 26627737 | DLD1 | viability | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 0.6397348217630983 | [351] | [103,157,240] | 6 | hSpCas9 | negative selection | 778832 | 48306990 | 48307013 | 11 | + | 26627737 | DLD1 | viability | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | 0.06280052156571164 | [645] | [224,340,90] | 0 | hSpCas9 | negative selection | 778833 | 48307004 | 48307027 | 11 | - | 26627737 | DLD1 | viability | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -0.4544671622773253 | [304] | [70,133,14] | -4 | hSpCas9 | negative selection | 778834 | 48307007 | 48307030 | 11 | - | 26627737 | DLD1 | viability | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | -0.6723893449361493 | [585] | [109,177,66] | -6 | hSpCas9 | negative selection | 778835 | 48306805 | 48306828 | 11 | + | 26627737 | GBM cells | viability after 5 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.7939046155961385 | [825] | [236,273] | -8 | hSpCas9 | negative selection | 861146 | 48306977 | 48307000 | 11 | - | 26627737 | GBM cells | viability after 5 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | -0.09031969424524429 | [266] | [117,150] | -1 | hSpCas9 | negative selection | 861147 | 48306990 | 48307013 | 11 | + | 26627737 | GBM cells | viability after 5 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.2028568030485371 | [322] | [158,141] | -3 | hSpCas9 | negative selection | 861148 | 48307004 | 48307027 | 11 | - | 26627737 | GBM cells | viability after 5 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -0.11073629514803374 | [299] | [163,133] | -2 | hSpCas9 | negative selection | 861149 | 48307007 | 48307030 | 11 | - | 26627737 | GBM cells | viability after 5 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.3911192346869892 | [181] | [102,152] | 6 | hSpCas9 | negative selection | 861150 | 48306805 | 48306828 | 11 | + | 26627737 | GBM cells | viability after 13 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.8752892687088709 | [825] | [181,294] | -7 | hSpCas9 | negative selection | 943461 | 48306977 | 48307000 | 11 | - | 26627737 | GBM cells | viability after 13 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | -0.6539934809078087 | [266] | [85,96] | -6 | hSpCas9 | negative selection | 943462 | 48306990 | 48307013 | 11 | + | 26627737 | GBM cells | viability after 13 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.1972867286979144 | [322] | [132,168] | -2 | hSpCas9 | negative selection | 943463 | 48307004 | 48307027 | 11 | - | 26627737 | GBM cells | viability after 13 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -0.23243735344647665 | [299] | [137,138] | -3 | hSpCas9 | negative selection | 943464 | 48307007 | 48307030 | 11 | - | 26627737 | GBM cells | viability after 13 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.8799449281565469 | [181] | [189,174] | 8 | hSpCas9 | negative selection | 943465 | 48306805 | 48306828 | 11 | + | 26627737 | GBM cells | viability after 21 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.47031052433141096 | [825] | [325,321] | -4 | hSpCas9 | negative selection | 1025776 | 48306977 | 48307000 | 11 | - | 26627737 | GBM cells | viability after 21 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 0.036768084148773375 | [266] | [129,165] | 0 | hSpCas9 | negative selection | 1025777 | 48306990 | 48307013 | 11 | + | 26627737 | GBM cells | viability after 21 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.024704503412735113 | [322] | [195,150] | 0 | hSpCas9 | negative selection | 1025778 | 48307004 | 48307027 | 11 | - | 26627737 | GBM cells | viability after 21 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -0.19320493723285254 | [299] | [152,132] | -2 | hSpCas9 | negative selection | 1025779 | 48307007 | 48307030 | 11 | - | 26627737 | GBM cells | viability after 21 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.9253211891441964 | [181] | [192,182] | 8 | hSpCas9 | negative selection | 1025780 | 48306805 | 48306828 | 11 | + | 26627737 | RPE1 | viability after 9 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.5539751947703289 | [2493] | [478,599] | -4 | hSpCas9 | negative selection | 1108091 | 48306977 | 48307000 | 11 | - | 26627737 | RPE1 | viability after 9 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 2.127306641986582 | [192] | [256,272] | 9 | hSpCas9 | negative selection | 1108092 | 48306990 | 48307013 | 11 | + | 26627737 | RPE1 | viability after 9 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | 0.5426077594180848 | [333] | [119,193] | 3 | hSpCas9 | negative selection | 1108093 | 48307004 | 48307027 | 11 | - | 26627737 | RPE1 | viability after 9 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -1.0992793588666103 | [954] | [70,227] | -7 | hSpCas9 | negative selection | 1108094 | 48307007 | 48307030 | 11 | - | 26627737 | RPE1 | viability after 9 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 1.375246964983476 | [493] | [343,474] | 7 | hSpCas9 | negative selection | 1108095 | 48306805 | 48306828 | 11 | + | 26627737 | RPE1 | viability after 12 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.24398597164764158 | [2493] | [524,608] | -2 | hSpCas9 | negative selection | 1190406 | 48306977 | 48307000 | 11 | - | 26627737 | RPE1 | viability after 12 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 2.4629490944527936 | [192] | [264,307] | 9 | hSpCas9 | negative selection | 1190407 | 48306990 | 48307013 | 11 | + | 26627737 | RPE1 | viability after 12 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.09773110974846633 | [333] | [95,70] | 0 | hSpCas9 | negative selection | 1190408 | 48307004 | 48307027 | 11 | - | 26627737 | RPE1 | viability after 12 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -1.1790595659660916 | [954] | [55,173] | -7 | hSpCas9 | negative selection | 1190409 | 48307007 | 48307030 | 11 | - | 26627737 | RPE1 | viability after 12 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.851712077242213 | [493] | [188,292] | 5 | hSpCas9 | negative selection | 1190410 | 48306805 | 48306828 | 11 | + | 26627737 | RPE1 | viability after 15 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.4158851782436217 | [2493] | [454,599] | -3 | hSpCas9 | negative selection | 1272721 | 48306977 | 48307000 | 11 | - | 26627737 | RPE1 | viability after 15 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 2.590044596327174 | [192] | [343,313] | 9 | hSpCas9 | negative selection | 1272722 | 48306990 | 48307013 | 11 | + | 26627737 | RPE1 | viability after 15 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.39688928042259586 | [333] | [0,139] | -2 | hSpCas9 | negative selection | 1272723 | 48307004 | 48307027 | 11 | - | 26627737 | RPE1 | viability after 15 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -0.5366428765724135 | [954] | [144,225] | -3 | hSpCas9 | negative selection | 1272724 | 48307007 | 48307030 | 11 | - | 26627737 | RPE1 | viability after 15 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 1.0267330620541504 | [493] | [300,268] | 6 | hSpCas9 | negative selection | 1272725 | 48306805 | 48306828 | 11 | + | 26627737 | RPE1 | viability after 18 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.3305179900626498 | [2493] | [454,620] | -2 | hSpCas9 | negative selection | 1355036 | 48306977 | 48307000 | 11 | - | 26627737 | RPE1 | viability after 18 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 2.7015860461585763 | [192] | [318,359] | 9 | hSpCas9 | negative selection | 1355037 | 48306990 | 48307013 | 11 | + | 26627737 | RPE1 | viability after 18 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | 0.34274725123977445 | [333] | [64,166] | 2 | hSpCas9 | negative selection | 1355038 | 48307004 | 48307027 | 11 | - | 26627737 | RPE1 | viability after 18 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -0.8623993277908379 | [954] | [90,195] | -5 | hSpCas9 | negative selection | 1355039 | 48307007 | 48307030 | 11 | - | 26627737 | RPE1 | viability after 18 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.8127172751437529 | [493] | [209,259] | 5 | hSpCas9 | negative selection | 1355040 | 48306805 | 48306828 | 11 | + | 26627737 | HeLa | viability after 8 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.6650548910242846 | [985] | [309,203,303] | -6 | hSpCas9 | negative selection | 1437351 | 48306977 | 48307000 | 11 | - | 26627737 | HeLa | viability after 8 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | -0.48642558391676044 | [602] | [305,79,200] | -5 | hSpCas9 | negative selection | 1437352 | 48306990 | 48307013 | 11 | + | 26627737 | HeLa | viability after 8 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | 0.4856813424196249 | [358] | [155,157,320] | 4 | hSpCas9 | negative selection | 1437353 | 48307004 | 48307027 | 11 | - | 26627737 | HeLa | viability after 8 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -0.40890434694436967 | [327] | [209,85,52] | -4 | hSpCas9 | negative selection | 1437354 | 48307007 | 48307030 | 11 | - | 26627737 | HeLa | viability after 8 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.4331394512606357 | [366] | [179,272,187] | 4 | hSpCas9 | negative selection | 1437355 | 48306805 | 48306828 | 11 | + | 26627737 | HeLa | viability after 12 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.46519578851617893 | [985] | [333,168,396] | -4 | hSpCas9 | negative selection | 1519666 | 48306977 | 48307000 | 11 | - | 26627737 | HeLa | viability after 12 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | -0.10891099392586423 | [602] | [374,168,159] | -1 | hSpCas9 | negative selection | 1519667 | 48306990 | 48307013 | 11 | + | 26627737 | HeLa | viability after 12 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.36978000461330085 | [358] | [126,112,104] | -3 | hSpCas9 | negative selection | 1519668 | 48307004 | 48307027 | 11 | - | 26627737 | HeLa | viability after 12 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | 0.2884324691982298 | [327] | [193,103,205] | 2 | hSpCas9 | negative selection | 1519669 | 48307007 | 48307030 | 11 | - | 26627737 | HeLa | viability after 12 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | -0.3355518176240484 | [366] | [113,123,121] | -3 | hSpCas9 | negative selection | 1519670 | 48306805 | 48306828 | 11 | + | 26627737 | HeLa | viability after 15 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.21010221423071762 | [985] | [532,322,168] | -2 | hSpCas9 | negative selection | 1601981 | 48306977 | 48307000 | 11 | - | 26627737 | HeLa | viability after 15 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | -0.8989263973275281 | [602] | [89,70,242] | -7 | hSpCas9 | negative selection | 1601982 | 48306990 | 48307013 | 11 | + | 26627737 | HeLa | viability after 15 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.21776166631981023 | [358] | [127,86,164] | -2 | hSpCas9 | negative selection | 1601983 | 48307004 | 48307027 | 11 | - | 26627737 | HeLa | viability after 15 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -0.23195381685671534 | [327] | [156,27,158] | -2 | hSpCas9 | negative selection | 1601984 | 48307007 | 48307030 | 11 | - | 26627737 | HeLa | viability after 15 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | -0.604325566870245 | [366] | [77,131,83] | -5 | hSpCas9 | negative selection | 1601985 | 48306805 | 48306828 | 11 | + | 26627737 | HeLa | viability after 18 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.2007018101731488 | [985] | [363,264,168] | -2 | hSpCas9 | negative selection | 1684296 | 48306977 | 48307000 | 11 | - | 26627737 | HeLa | viability after 18 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | -0.8502848300298411 | [602] | [64,63,242] | -6 | hSpCas9 | negative selection | 1684297 | 48306990 | 48307013 | 11 | + | 26627737 | HeLa | viability after 18 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.21136926327830932 | [358] | [82,76,164] | -2 | hSpCas9 | negative selection | 1684298 | 48307004 | 48307027 | 11 | - | 26627737 | HeLa | viability after 18 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -0.23646000761510838 | [327] | [103,23,158] | -2 | hSpCas9 | negative selection | 1684299 | 48307007 | 48307030 | 11 | - | 26627737 | HeLa | viability after 18 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | -0.6408196615941919 | [366] | [50,104,83] | -5 | hSpCas9 | negative selection | 1684300 | 48306805 | 48306828 | 11 | + | 26627737 | HCT116 | viability after 6 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.12952920145606384 | [1547] | [264,198] | 0 | hSpCas9 | negative selection | 1766611 | 48306977 | 48307000 | 11 | - | 26627737 | HCT116 | viability after 6 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 3.6659058555943376 | [400] | [94,1188] | 9 | hSpCas9 | negative selection | 1766612 | 48306990 | 48307013 | 11 | + | 26627737 | HCT116 | viability after 6 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.044334944809158505 | [790] | [195,78] | 0 | hSpCas9 | negative selection | 1766613 | 48307004 | 48307027 | 11 | - | 26627737 | HCT116 | viability after 6 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | 0.2738309179703273 | [721] | [104,154] | 1 | hSpCas9 | negative selection | 1766614 | 48307007 | 48307030 | 11 | - | 26627737 | HCT116 | viability after 6 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 1.4478596457484665 | [486] | [126,253] | 7 | hSpCas9 | negative selection | 1766615 | 48306805 | 48306828 | 11 | + | 26627737 | HCT116 | viability after 8 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 0.029341278122019476 | [718] | [359,431,419] | 0 | hSpCas9 | negative selection | 1848926 | 48306977 | 48307000 | 11 | - | 26627737 | HCT116 | viability after 8 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 0.13851235794452108 | [285] | [87,265,164] | 1 | hSpCas9 | negative selection | 1848927 | 48306990 | 48307013 | 11 | + | 26627737 | HCT116 | viability after 8 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.5969327093288781 | [405] | [148,166,127] | -6 | hSpCas9 | negative selection | 1848928 | 48307004 | 48307027 | 11 | - | 26627737 | HCT116 | viability after 8 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | 0.6565981669874352 | [239] | [189,137,295] | 6 | hSpCas9 | negative selection | 1848929 | 48307007 | 48307030 | 11 | - | 26627737 | HCT116 | viability after 8 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | -0.3746825386857013 | [215] | [98,123,52] | -4 | hSpCas9 | negative selection | 1848930 | 48306805 | 48306828 | 11 | + | 26627737 | HCT116 | viability after 9 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 0.14200356552686189 | [1547] | [602,339] | 1 | hSpCas9 | negative selection | 1931241 | 48306977 | 48307000 | 11 | - | 26627737 | HCT116 | viability after 9 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 0.49688263339483213 | [400] | [111,181] | 3 | hSpCas9 | negative selection | 1931242 | 48306990 | 48307013 | 11 | + | 26627737 | HCT116 | viability after 9 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | 0.9770830879510697 | [790] | [355,462] | 6 | hSpCas9 | negative selection | 1931243 | 48307004 | 48307027 | 11 | - | 26627737 | HCT116 | viability after 9 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -1.1807099376346046 | [721] | [117,58] | -7 | hSpCas9 | negative selection | 1931244 | 48307007 | 48307030 | 11 | - | 26627737 | HCT116 | viability after 9 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.2418869019549995 | [486] | [298,38] | 1 | hSpCas9 | negative selection | 1931245 | 48306805 | 48306828 | 11 | + | 26627737 | HCT116 | viability after 12 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 0.6106108524881535 | [718] | [509,505,718] | 6 | hSpCas9 | negative selection | 2013556 | 48306977 | 48307000 | 11 | - | 26627737 | HCT116 | viability after 12 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | -0.18186271302671517 | [285] | [55,205,143] | -2 | hSpCas9 | negative selection | 2013557 | 48306990 | 48307013 | 11 | + | 26627737 | HCT116 | viability after 12 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.0388980098341582 | [405] | [252,162,201] | 0 | hSpCas9 | negative selection | 2013558 | 48307004 | 48307027 | 11 | - | 26627737 | HCT116 | viability after 12 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | 0.31041272885929916 | [239] | [85,139,248] | 3 | hSpCas9 | negative selection | 2013559 | 48307007 | 48307030 | 11 | - | 26627737 | HCT116 | viability after 12 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | -0.08340930147541575 | [215] | [68,116,138] | -1 | hSpCas9 | negative selection | 2013560 | 48306805 | 48306828 | 11 | + | 26627737 | HCT116 | viability after 15 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 0.07505399336053742 | [718] | [358,446,488] | 0 | hSpCas9 | negative selection | 2095871 | 48306977 | 48307000 | 11 | - | 26627737 | HCT116 | viability after 15 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 0.007650671111533162 | [285] | [203,205,90] | 0 | hSpCas9 | negative selection | 2095872 | 48306990 | 48307013 | 11 | + | 26627737 | HCT116 | viability after 15 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.99823229637665 | [405] | [152,118,82] | -7 | hSpCas9 | negative selection | 2095873 | 48307004 | 48307027 | 11 | - | 26627737 | HCT116 | viability after 15 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | 0.6346062165448378 | [239] | [177,197,260] | 6 | hSpCas9 | negative selection | 2095874 | 48307007 | 48307030 | 11 | - | 26627737 | HCT116 | viability after 15 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.007033083082114477 | [215] | [122,145,104] | 0 | hSpCas9 | negative selection | 2095875 | 48306805 | 48306828 | 11 | + | 26627737 | HCT116 | viability after 18 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 0.4594487758101231 | [718] | [483,345,618] | 4 | hSpCas9 | negative selection | 2178186 | 48306977 | 48307000 | 11 | - | 26627737 | HCT116 | viability after 18 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 0.20525671474828966 | [285] | [219,144,111] | 1 | hSpCas9 | negative selection | 2178187 | 48306990 | 48307013 | 11 | + | 26627737 | HCT116 | viability after 18 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.12640261033530525 | [405] | [236,65,246] | -1 | hSpCas9 | negative selection | 2178188 | 48307004 | 48307027 | 11 | - | 26627737 | HCT116 | viability after 18 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | 0.7767694844686872 | [239] | [86,264,241] | 6 | hSpCas9 | negative selection | 2178189 | 48307007 | 48307030 | 11 | - | 26627737 | HCT116 | viability after 18 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.26735653919504565 | [215] | [122,152,97] | 2 | hSpCas9 | negative selection | 2178190 | 48306601 | 48306624 | 11 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | ATGATGGCTGTGTAGTGCAGGGG | OR4S1 | ENSG00000176555 | 0.343205783456906 | [3,3] | [2,4] | 7 | hSpCas9 | positive selection | 3008242 | 48306555 | 48306578 | 11 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CATAGGCCATGGCTGTAAGGAGG | OR4S1 | ENSG00000176555 | -0.07444854576618926 | [3,3] | [5,1] | -1 | hSpCas9 | positive selection | 3008243 | 48306264 | 48306287 | 11 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCATCTCTCTGCTCTCAAAAAGG | OR4S1 | ENSG00000176555 | 0.057735348615466114 | [3,4] | [3,3] | 1 | hSpCas9 | positive selection | 3008244 | 48306312 | 48306335 | 11 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGACAGTGAGCACATGAAAGAGG | OR4S1 | ENSG00000176555 | -0.34400741436439625 | [4,4] | [3,2] | -5 | hSpCas9 | positive selection | 3008245 | 48306601 | 48306624 | 11 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | ATGATGGCTGTGTAGTGCAGGGG | OR4S1 | ENSG00000176555 | 0.0001009285579149366 | [3,3] | [3,1] | 0 | hSpCas9 | positive selection | 3076100 | 48306555 | 48306578 | 11 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CATAGGCCATGGCTGTAAGGAGG | OR4S1 | ENSG00000176555 | -0.0852133375396833 | [3,3] | [2,1] | -1 | hSpCas9 | positive selection | 3076101 | 48306264 | 48306287 | 11 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCATCTCTCTGCTCTCAAAAAGG | OR4S1 | ENSG00000176555 | 0.3716210682245462 | [3,3] | [4,3] | 6 | hSpCas9 | positive selection | 3076102 | 48306312 | 48306335 | 11 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGACAGTGAGCACATGAAAGAGG | OR4S1 | ENSG00000176555 | 0.4887035589032129 | [4,4] | [5,3] | 8 | hSpCas9 | positive selection | 3076103 | 48306805 | 48306828 | | + | 24336571 | A375 | resistance to PLX after 7 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 0.18599657329601205 | [5,6] | [7,5] | 6 | hSpCas9 | positive selection | 3132924 | 48306818 | 48306841 | | - | 24336571 | A375 | resistance to PLX after 7 days | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.533516256036242 | [8,6] | [4,5] | -9 | hSpCas9 | positive selection | 3132925 | 48306805 | 48306828 | | + | 24336571 | A375 | resistance to PLX after 14 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.04207810134817369 | [3,7] | [1,2] | 0 | hSpCas9 | positive selection | 3190717 | 48306818 | 48306841 | | - | 24336571 | A375 | resistance to PLX after 14 days | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.8832643901102477 | [10,7] | [1,1] | -9 | hSpCas9 | positive selection | 3190718 | 48306805 | 48306828 | | + | 24336571 | A375 | viability after 7 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.4185339735379965 | [8] | [5,6] | -5 | hSpCas9 | negative selection | 3248510 | 48306818 | 48306841 | | - | 24336571 | A375 | viability after 7 days | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.18248525070612936 | [9] | [8,6] | -3 | hSpCas9 | negative selection | 3248511 | 48306805 | 48306828 | | + | 24336571 | A375 | viability after 14 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.47821142000579553 | [8] | [3,7] | -5 | hSpCas9 | negative selection | 3306303 | 48306818 | 48306841 | | - | 24336571 | A375 | viability after 14 days | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | 0.03375658240721141 | [9] | [10,7] | 0 | hSpCas9 | negative selection | 3306304 | 48306642 | 48306665 | 11 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 5.257326211445835 | [3,3] | [0,0] | 9 | hSpCas9 | positive selection | 3383616 | 48306805 | 48306828 | 11 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 0.3148117061065953 | [122,122] | [0,0] | 1 | hSpCas9 | positive selection | 3383617 | 48306791 | 48306814 | 11 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.3425866307412928 | [193,193] | [0,0] | -2 | hSpCas9 | positive selection | 3383618 | 48306601 | 48306624 | 11 | - | 26780180 | HT29 | viability (Avana library 4 designs) | ATGATGGCTGTGTAGTGCAGGGG | OR4S1 | ENSG00000176555 | 3.06660294735553 | [] | [] | 8 | hSpCas9 | negative selection | 3446222 | 48306555 | 48306578 | 11 | - | 26780180 | HT29 | viability (Avana library 4 designs) | CATAGGCCATGGCTGTAAGGAGG | OR4S1 | ENSG00000176555 | 0.0761521502572556 | [] | [] | 0 | hSpCas9 | negative selection | 3446223 | 48306264 | 48306287 | 11 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GCATCTCTCTGCTCTCAAAAAGG | OR4S1 | ENSG00000176555 | -0.239874670130927 | [] | [] | -4 | hSpCas9 | negative selection | 3446224 | 48306312 | 48306335 | 11 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GGACAGTGAGCACATGAAAGAGG | OR4S1 | ENSG00000176555 | -0.183420976875745 | [] | [] | -3 | hSpCas9 | negative selection | 3446225 | 48306312 | 48306335 | 11 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGACAGTGAGCACATGAAAGAGG | OR4S1 | ENSG00000176555 | 4.07234337146515 | [] | [] | 6 | hSpCas9 | negative selection | 3539434 | 48306264 | 48306287 | 11 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCATCTCTCTGCTCTCAAAAAGG | OR4S1 | ENSG00000176555 | 0.014754074030405 | [] | [] | 0 | hSpCas9 | negative selection | 3539435 | 48306555 | 48306578 | 11 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CATAGGCCATGGCTGTAAGGAGG | OR4S1 | ENSG00000176555 | 3.92705927009159 | [] | [] | 6 | hSpCas9 | negative selection | 3539436 | 48306601 | 48306624 | 11 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ATGATGGCTGTGTAGTGCAGGGG | OR4S1 | ENSG00000176555 | -3.92051104710951 | [] | [] | -4 | hSpCas9 | negative selection | 3539437 | 48306656 | 48306679 | 11 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CAGGAAGCCAGCTAACCAGGAGG | OR4S1 | ENSG00000176555 | -1.34397993915052 | [] | [] | -2 | hSpCas9 | negative selection | 3539438 | 48306317 | 48306340 | 11 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TTCATGTGCTCACTGTCCTGGGG | OR4S1 | ENSG00000176555 | 1.01075468010391 | [] | [] | 1 | hSpCas9 | negative selection | 3539439 | 48306312 | 48306335 | 11 | - | 26780180 | A375 | viability (Avana lentiGuide) | GGACAGTGAGCACATGAAAGAGG | OR4S1 | ENSG00000176555 | 1.37086823558495 | [] | [] | 1 | hSpCas9 | negative selection | 3648093 | 48306264 | 48306287 | 11 | - | 26780180 | A375 | viability (Avana lentiGuide) | GCATCTCTCTGCTCTCAAAAAGG | OR4S1 | ENSG00000176555 | -8.77791563048538 | [] | [] | -9 | hSpCas9 | negative selection | 3648094 | 48306555 | 48306578 | 11 | - | 26780180 | A375 | viability (Avana lentiGuide) | CATAGGCCATGGCTGTAAGGAGG | OR4S1 | ENSG00000176555 | 13.4889970045552 | [] | [] | 7 | hSpCas9 | negative selection | 3648095 | 48306601 | 48306624 | 11 | - | 26780180 | A375 | viability (Avana lentiGuide) | ATGATGGCTGTGTAGTGCAGGGG | OR4S1 | ENSG00000176555 | 22.0091711573961 | [] | [] | 9 | hSpCas9 | negative selection | 3648096 | 48306656 | 48306679 | 11 | - | 26780180 | A375 | viability (Avana lentiGuide) | CAGGAAGCCAGCTAACCAGGAGG | OR4S1 | ENSG00000176555 | -0.481467476027647 | [] | [] | 0 | hSpCas9 | negative selection | 3648097 | 48306317 | 48306340 | 11 | + | 26780180 | A375 | viability (Avana lentiGuide) | TTCATGTGCTCACTGTCCTGGGG | OR4S1 | ENSG00000176555 | 4.19221451200441 | [] | [] | 4 | hSpCas9 | negative selection | 3648098 | 48306312 | 48306335 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGACAGTGAGCACATGAAAGAGG | OR4S1 | ENSG00000176555 | 0.11841468723388954 | [5] | [6,5] | 3 | hSpCas9 | positive selection | 3756752 | 48306264 | 48306287 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCATCTCTCTGCTCTCAAAAAGG | OR4S1 | ENSG00000176555 | -0.26983214383487525 | [5] | [4,3] | -4 | hSpCas9 | positive selection | 3756753 | 48306555 | 48306578 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CATAGGCCATGGCTGTAAGGAGG | OR4S1 | ENSG00000176555 | -0.011406835279878406 | [5] | [4,4] | 0 | hSpCas9 | positive selection | 3756754 | 48306601 | 48306624 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ATGATGGCTGTGTAGTGCAGGGG | OR4S1 | ENSG00000176555 | -0.2736401548771109 | [5] | [4,4] | -4 | hSpCas9 | positive selection | 3756755 | 48306656 | 48306679 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CAGGAAGCCAGCTAACCAGGAGG | OR4S1 | ENSG00000176555 | -0.28146566371172116 | [4] | [3,2] | -4 | hSpCas9 | positive selection | 3756756 | 48306317 | 48306340 | 11 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TTCATGTGCTCACTGTCCTGGGG | OR4S1 | ENSG00000176555 | 0.08035025132295953 | [5] | [5,5] | 2 | hSpCas9 | positive selection | 3756757 | 48306312 | 48306335 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGACAGTGAGCACATGAAAGAGG | OR4S1 | ENSG00000176555 | -0.270248554307196 | [6] | [2,5] | -4 | hSpCas9 | positive selection | 3865359 | 48306264 | 48306287 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCATCTCTCTGCTCTCAAAAAGG | OR4S1 | ENSG00000176555 | -0.17879637194993658 | [5] | [4,2] | -2 | hSpCas9 | positive selection | 3865360 | 48306555 | 48306578 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CATAGGCCATGGCTGTAAGGAGG | OR4S1 | ENSG00000176555 | -0.5965035669404141 | [5] | [1,3] | -6 | hSpCas9 | positive selection | 3865361 | 48306601 | 48306624 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ATGATGGCTGTGTAGTGCAGGGG | OR4S1 | ENSG00000176555 | -0.5235851894780101 | [5] | [2,2] | -6 | hSpCas9 | positive selection | 3865362 | 48306656 | 48306679 | 11 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CAGGAAGCCAGCTAACCAGGAGG | OR4S1 | ENSG00000176555 | -0.15962000896785344 | [4] | [4,2] | -2 | hSpCas9 | positive selection | 3865363 | 48306317 | 48306340 | 11 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TTCATGTGCTCACTGTCCTGGGG | OR4S1 | ENSG00000176555 | 0.028831428053583158 | [6] | [5,4] | 0 | hSpCas9 | positive selection | 3865364 | 48306617 | 48306640 | 11 | - | 26780180 | A375 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 1.09758936413108 | [] | [] | 5 | hSpCas9 | negative selection | 3976277 | 48306642 | 48306665 | 11 | - | 26780180 | A375 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.228245777464284 | [] | [] | 0 | hSpCas9 | negative selection | 3976278 | 48306791 | 48306814 | 11 | - | 26780180 | A375 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | 1.01678065341595 | [] | [] | 5 | hSpCas9 | negative selection | 3976279 | 48306805 | 48306828 | 11 | + | 26780180 | A375 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 1.80991414868542 | [] | [] | 9 | hSpCas9 | negative selection | 3976280 | 48306818 | 48306841 | 11 | - | 26780180 | A375 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | 1.13487200710786 | [] | [] | 6 | hSpCas9 | negative selection | 3976281 | 48306897 | 48306920 | 11 | - | 26780180 | A375 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.57844023970946 | [] | [] | 1 | hSpCas9 | negative selection | 3976282 | 48306617 | 48306640 | 11 | - | 26780180 | HT29 | viability (GeCKOv2 library) | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.806634677833494 | [] | [] | 3 | hSpCas9 | negative selection | 4084243 | 48306642 | 48306665 | 11 | - | 26780180 | HT29 | viability (GeCKOv2 library) | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.359104850548085 | [] | [] | 1 | hSpCas9 | negative selection | 4084244 | 48306791 | 48306814 | 11 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | 1.36547829702375 | [] | [] | 7 | hSpCas9 | negative selection | 4084245 | 48306805 | 48306828 | 11 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 1.56241594901084 | [] | [] | 8 | hSpCas9 | negative selection | 4084246 | 48306818 | 48306841 | 11 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | 1.11182615982524 | [] | [] | 5 | hSpCas9 | negative selection | 4084247 | 48306897 | 48306920 | 11 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 1.20065441002081 | [] | [] | 6 | hSpCas9 | negative selection | 4084248 | 48306805 | 48306828 | 11 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 0.3128768996468123 | [2] | [3,0] | 7 | hSpCas9 | positive selection | 4157728 | 48306818 | 48306841 | 11 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.26949290646783414 | [2] | [1,0] | -6 | hSpCas9 | positive selection | 4157729 | 48306805 | 48306828 | 11 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 0.011183942494942839 | [3] | [0,2,2,0] | 0 | hSpCas9 | positive selection | 4221750 | 48306818 | 48306841 | 11 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.04904212507323674 | [2] | [0,2,0,0] | 0 | hSpCas9 | positive selection | 4221751 | 48306617 | 48306640 | 11 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.010031643097027032 | [2] | [1,1] | 0 | hSpCas9 | positive selection | 4287711 | 48306818 | 48306841 | 11 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.08180049975837739 | [3] | [3,1] | -2 | hSpCas9 | positive selection | 4287712 | 48306897 | 48306920 | 11 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | -0.061911462659867605 | [3] | [3,1] | -1 | hSpCas9 | positive selection | 4287713 | 48306642 | 48306665 | 11 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.0016069466630546092 | [0] | [0,0] | 0 | hSpCas9 | positive selection | 4351967 | 48306805 | 48306828 | 11 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -1.0876007532111884 | [2] | [0,0] | -9 | hSpCas9 | positive selection | 4351968 | 48306791 | 48306814 | 11 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | 0.16069542032354622 | [3] | [2,3] | 3 | hSpCas9 | positive selection | 4351969 | 48306312 | 48306335 | 11 | - | 27661255 | K562 | viability | GGACAGTGAGCACATGAAAGAGG | OR4S1 | ENSG00000176555 | -0.029283450984127324 | [1829,1500] | [1425,1207] | -1 | dCas9-KRAB | negative selection | 5499046 | 48306617 | 48306640 | 11 | - | 27260156 | BXPC3 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.07875129064452191 | [228] | [180,201,271,381] | 1 | hSpCas9 | negative selection | 5560171 | 48306818 | 48306841 | 11 | - | 27260156 | BXPC3 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.3735731186062208 | [625] | [398,595,496,534] | -7 | hSpCas9 | negative selection | 5560172 | 48306897 | 48306920 | 11 | - | 27260156 | BXPC3 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.2729290265773924 | [893] | [1078,1066,1120,1268] | 6 | hSpCas9 | negative selection | 5560173 | 48306642 | 48306665 | 11 | - | 27260156 | BXPC3 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.6074567412049712 | [15] | [15,31,32,20] | 9 | hSpCas9 | negative selection | 5624427 | 48306805 | 48306828 | 11 | + | 27260156 | BXPC3 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.5805963068617451 | [342] | [222,230,277,226] | -8 | hSpCas9 | negative selection | 5624428 | 48306791 | 48306814 | 11 | - | 27260156 | BXPC3 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.3467952334681035 | [609] | [480,505,480,540] | -7 | hSpCas9 | negative selection | 5624429 | 48306617 | 48306640 | 11 | - | 27260156 | A673 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.06826186584182836 | [228] | [291,238,296,221] | -2 | hSpCas9 | negative selection | 5681422 | 48306818 | 48306841 | 11 | - | 27260156 | A673 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.3603993039381521 | [625] | [680,510,530,633] | -7 | hSpCas9 | negative selection | 5681423 | 48306897 | 48306920 | 11 | - | 27260156 | A673 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.17414483336017839 | [893] | [1132,1216,1176,1311] | 4 | hSpCas9 | negative selection | 5681424 | 48306642 | 48306665 | 11 | - | 27260156 | A673 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.0995359157717548 | [15] | [13,8,20,27] | -2 | hSpCas9 | negative selection | 5745678 | 48306805 | 48306828 | 11 | + | 27260156 | A673 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.9270684404585569 | [342] | [230,146,287,201] | -9 | hSpCas9 | negative selection | 5745679 | 48306791 | 48306814 | 11 | - | 27260156 | A673 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.2389376415937459 | [609] | [712,561,579,639] | -5 | hSpCas9 | negative selection | 5745680 | 48306617 | 48306640 | 11 | - | 27260156 | A375 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.02272309918658899 | [228] | [222,314,258,291] | 0 | hSpCas9 | negative selection | 5802673 | 48306818 | 48306841 | 11 | - | 27260156 | A375 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.502065619603894 | [625] | [585,428,626,420] | -6 | hSpCas9 | negative selection | 5802674 | 48306897 | 48306920 | 11 | - | 27260156 | A375 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.4224292123143928 | [893] | [1337,1361,1528,1361] | 6 | hSpCas9 | negative selection | 5802675 | 48306642 | 48306665 | 11 | - | 27260156 | A375 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.45412716988247936 | [15] | [57,6,18,16] | 6 | hSpCas9 | negative selection | 5866929 | 48306805 | 48306828 | 11 | + | 27260156 | A375 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -1.0890280621984822 | [342] | [166,245,145,199] | -8 | hSpCas9 | negative selection | 5866930 | 48306791 | 48306814 | 11 | - | 27260156 | A375 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.6346600176971231 | [609] | [475,542,555,290] | -7 | hSpCas9 | negative selection | 5866931 | 48306617 | 48306640 | 11 | - | 27260156 | COLO741 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.07683345382869533 | [228] | [417,288,232] | 1 | hSpCas9 | negative selection | 5923924 | 48306818 | 48306841 | 11 | - | 27260156 | COLO741 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.05319381850973587 | [625] | [920,737,671] | -1 | hSpCas9 | negative selection | 5923925 | 48306897 | 48306920 | 11 | - | 27260156 | COLO741 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.42565807919034915 | [893] | [1761,1485,1381] | 8 | hSpCas9 | negative selection | 5923926 | 48306642 | 48306665 | 11 | - | 27260156 | COLO741 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -2.031061946381703 | [15] | [5,2,5] | -9 | hSpCas9 | negative selection | 5988180 | 48306805 | 48306828 | 11 | + | 27260156 | COLO741 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.8261326797666663 | [342] | [200,327,210] | -9 | hSpCas9 | negative selection | 5988181 | 48306791 | 48306814 | 11 | - | 27260156 | COLO741 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.20448247171577447 | [609] | [781,599,655] | -4 | hSpCas9 | negative selection | 5988182 | 48306617 | 48306640 | 11 | - | 27260156 | CAL120 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.30430939161554016 | [228] | [469,347,256] | 4 | hSpCas9 | negative selection | 6045175 | 48306818 | 48306841 | 11 | - | 27260156 | CAL120 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.31053469032408904 | [625] | [508,493,858] | -4 | hSpCas9 | negative selection | 6045176 | 48306897 | 48306920 | 11 | - | 27260156 | CAL120 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.49037017284405515 | [893] | [1322,1780,1547] | 7 | hSpCas9 | negative selection | 6045177 | 48306642 | 48306665 | 11 | - | 27260156 | CAL120 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.9963618187749015 | [15] | [3,12,11] | -8 | hSpCas9 | negative selection | 6109431 | 48306805 | 48306828 | 11 | + | 27260156 | CAL120 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.07003689519763923 | [342] | [256,414,522] | -1 | hSpCas9 | negative selection | 6109432 | 48306791 | 48306814 | 11 | - | 27260156 | CAL120 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.22374833820045475 | [609] | [731,739,492] | -3 | hSpCas9 | negative selection | 6109433 | 48306617 | 48306640 | 11 | - | 27260156 | CADOES1 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.11996889287334267 | [228] | [191,162,280,145] | -2 | hSpCas9 | negative selection | 6166426 | 48306818 | 48306841 | 11 | - | 27260156 | CADOES1 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.1460106053931829 | [625] | [639,402,487,574] | -3 | hSpCas9 | negative selection | 6166427 | 48306897 | 48306920 | 11 | - | 27260156 | CADOES1 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.3259111492916097 | [893] | [1285,959,805,1118] | 5 | hSpCas9 | negative selection | 6166428 | 48306642 | 48306665 | 11 | - | 27260156 | CADOES1 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 1.4150278224081276 | [15] | [5,126,11,12] | 9 | hSpCas9 | negative selection | 6230682 | 48306805 | 48306828 | 11 | + | 27260156 | CADOES1 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -1.0031762343328032 | [342] | [231,81,169,151] | -9 | hSpCas9 | negative selection | 6230683 | 48306791 | 48306814 | 11 | - | 27260156 | CADOES1 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.48989990709668274 | [609] | [394,329,455,435] | -7 | hSpCas9 | negative selection | 6230684 | 48306617 | 48306640 | 11 | - | 27260156 | EWS502 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.18848364926859928 | [228] | [303,229,171,125] | -3 | hSpCas9 | negative selection | 6287677 | 48306818 | 48306841 | 11 | - | 27260156 | EWS502 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | 0.07274572427805037 | [625] | [718,398,874,813] | 1 | hSpCas9 | negative selection | 6287678 | 48306897 | 48306920 | 11 | - | 27260156 | EWS502 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.32155648018719074 | [893] | [1019,1292,1231,1200] | 5 | hSpCas9 | negative selection | 6287679 | 48306642 | 48306665 | 11 | - | 27260156 | EWS502 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 1.0348568354227088 | [15] | [2,18,118,0] | 9 | hSpCas9 | negative selection | 6351933 | 48306805 | 48306828 | 11 | + | 27260156 | EWS502 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.8042741113202757 | [342] | [248,214,190,167] | -8 | hSpCas9 | negative selection | 6351934 | 48306791 | 48306814 | 11 | - | 27260156 | EWS502 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.3671598212785308 | [609] | [435,465,682,422] | -6 | hSpCas9 | negative selection | 6351935 | 48306617 | 48306640 | 11 | - | 27260156 | EW8 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.36488919271680165 | [228] | [180,159,121,120] | -6 | hSpCas9 | negative selection | 6408928 | 48306818 | 48306841 | 11 | - | 27260156 | EW8 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.251268752205038 | [625] | [393,395,370,547] | -5 | hSpCas9 | negative selection | 6408929 | 48306897 | 48306920 | 11 | - | 27260156 | EW8 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.28532047029600827 | [893] | [942,755,786,1064] | 5 | hSpCas9 | negative selection | 6408930 | 48306642 | 48306665 | 11 | - | 27260156 | EW8 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.29601882104477717 | [15] | [5,15,18,20] | 5 | hSpCas9 | negative selection | 6473184 | 48306805 | 48306828 | 11 | + | 27260156 | EW8 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.5949026754472443 | [342] | [255,149,108,240] | -8 | hSpCas9 | negative selection | 6473185 | 48306791 | 48306814 | 11 | - | 27260156 | EW8 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.3581816289678427 | [609] | [384,525,376,255] | -6 | hSpCas9 | negative selection | 6473186 | 48306617 | 48306640 | 11 | - | 27260156 | CORL105 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.4481305721527189 | [228] | [186,228,195,172] | -7 | hSpCas9 | negative selection | 6530179 | 48306818 | 48306841 | 11 | - | 27260156 | CORL105 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.10518830080258557 | [625] | [663,449,962,695] | -2 | hSpCas9 | negative selection | 6530180 | 48306897 | 48306920 | 11 | - | 27260156 | CORL105 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.20061523339489573 | [893] | [960,1144,1645,1120] | 4 | hSpCas9 | negative selection | 6530181 | 48306642 | 48306665 | 11 | - | 27260156 | CORL105 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.614792552063764 | [15] | [24,22,61,9] | 9 | hSpCas9 | negative selection | 6594435 | 48306805 | 48306828 | 11 | + | 27260156 | CORL105 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.3802901037172799 | [342] | [394,267,296,275] | -6 | hSpCas9 | negative selection | 6594436 | 48306791 | 48306814 | 11 | - | 27260156 | CORL105 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.48316140838803673 | [609] | [459,622,587,380] | -7 | hSpCas9 | negative selection | 6594437 | 48306617 | 48306640 | 11 | - | 27260156 | HS294T | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.14481562710701978 | [228] | [43,165,91,90] | 2 | hSpCas9 | negative selection | 6651430 | 48306818 | 48306841 | 11 | - | 27260156 | HS294T | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | 0.3084824753572571 | [625] | [204,408,191,416] | 4 | hSpCas9 | negative selection | 6651431 | 48306897 | 48306920 | 11 | - | 27260156 | HS294T | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.21388939356468561 | [893] | [318,413,454,425] | 3 | hSpCas9 | negative selection | 6651432 | 48306642 | 48306665 | 11 | - | 27260156 | HS294T | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.13055587502716026 | [15] | [5,3,9,1] | -2 | hSpCas9 | negative selection | 6715686 | 48306805 | 48306828 | 11 | + | 27260156 | HS294T | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.9922631872873121 | [342] | [53,58,82,72] | -8 | hSpCas9 | negative selection | 6715687 | 48306791 | 48306814 | 11 | - | 27260156 | HS294T | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.4905477904494442 | [609] | [183,139,164,183] | -6 | hSpCas9 | negative selection | 6715688 | 48306617 | 48306640 | 11 | - | 27260156 | HCC44 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.26287037004701364 | [228] | [268,163,257,190] | -4 | hSpCas9 | negative selection | 6772681 | 48306818 | 48306841 | 11 | - | 27260156 | HCC44 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.086240559308782 | [625] | [742,637,668,624] | -1 | hSpCas9 | negative selection | 6772682 | 48306897 | 48306920 | 11 | - | 27260156 | HCC44 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.4099117891973846 | [893] | [1400,1320,1568,1125] | 6 | hSpCas9 | negative selection | 6772683 | 48306642 | 48306665 | 11 | - | 27260156 | HCC44 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -1.1538318750473024 | [15] | [8,18,0,0] | -9 | hSpCas9 | negative selection | 6836937 | 48306805 | 48306828 | 11 | + | 27260156 | HCC44 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.47658121357419736 | [342] | [223,311,379,206] | -6 | hSpCas9 | negative selection | 6836938 | 48306791 | 48306814 | 11 | - | 27260156 | HCC44 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.3087120214506555 | [609] | [728,312,766,502] | -5 | hSpCas9 | negative selection | 6836939 | 48306617 | 48306640 | 11 | - | 27260156 | G402 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.7044657352439941 | [228] | [705,210,774,163] | 8 | hSpCas9 | negative selection | 6893932 | 48306818 | 48306841 | 11 | - | 27260156 | G402 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.5593412248564809 | [625] | [630,728,180,556] | -6 | hSpCas9 | negative selection | 6893933 | 48306897 | 48306920 | 11 | - | 27260156 | G402 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.10095020835199675 | [893] | [1608,1074,1068,988] | 1 | hSpCas9 | negative selection | 6893934 | 48306642 | 48306665 | 11 | - | 27260156 | G402 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.038070057804850954 | [15] | [12,8,0,49] | 0 | hSpCas9 | negative selection | 6958188 | 48306805 | 48306828 | 11 | + | 27260156 | G402 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.6037127125880973 | [342] | [222,199,418,247] | -6 | hSpCas9 | negative selection | 6958189 | 48306791 | 48306814 | 11 | - | 27260156 | G402 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.28503743787139885 | [609] | [615,409,915,493] | -4 | hSpCas9 | negative selection | 6958190 | 48306617 | 48306640 | 11 | - | 27260156 | L33 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.2261263047152845 | [228] | [355,143,125,161] | 5 | hSpCas9 | negative selection | 7015183 | 48306818 | 48306841 | 11 | - | 27260156 | L33 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | 0.05586486457644879 | [625] | [662,233,445,658] | 1 | hSpCas9 | negative selection | 7015184 | 48306897 | 48306920 | 11 | - | 27260156 | L33 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.1627430632170076 | [893] | [906,392,760,929] | 3 | hSpCas9 | negative selection | 7015185 | 48306642 | 48306665 | 11 | - | 27260156 | L33 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -1.1700844675372544 | [15] | [16,0,2,3] | -9 | hSpCas9 | negative selection | 7079439 | 48306805 | 48306828 | 11 | + | 27260156 | L33 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.8220199754485392 | [342] | [241,73,99,192] | -9 | hSpCas9 | negative selection | 7079440 | 48306791 | 48306814 | 11 | - | 27260156 | L33 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.250298608283833 | [609] | [469,217,398,416] | -5 | hSpCas9 | negative selection | 7079441 | 48306617 | 48306640 | 11 | - | 27260156 | K562 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.4015117057530142 | [228] | [263,228,212,353] | 5 | hSpCas9 | negative selection | 7136434 | 48306818 | 48306841 | 11 | - | 27260156 | K562 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | 0.10264360702409275 | [625] | [1128,465,594,268] | 1 | hSpCas9 | negative selection | 7136435 | 48306897 | 48306920 | 11 | - | 27260156 | K562 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.422714241221371 | [893] | [1494,1038,1078,711] | 5 | hSpCas9 | negative selection | 7136436 | 48306642 | 48306665 | 11 | - | 27260156 | K562 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.4902320618316658 | [15] | [6,5,26,0] | -5 | hSpCas9 | negative selection | 7200690 | 48306805 | 48306828 | 11 | + | 27260156 | K562 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.8571579054261941 | [342] | [164,169,259,85] | -7 | hSpCas9 | negative selection | 7200691 | 48306791 | 48306814 | 11 | - | 27260156 | K562 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.45946885876391497 | [609] | [500,506,338,256] | -5 | hSpCas9 | negative selection | 7200692 | 48306617 | 48306640 | 11 | - | 27260156 | HT29 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.013988755851219725 | [228] | [335,322,206,265] | 0 | hSpCas9 | negative selection | 7257685 | 48306818 | 48306841 | 11 | - | 27260156 | HT29 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | 0.0283506849116944 | [625] | [730,866,791,719] | 0 | hSpCas9 | negative selection | 7257686 | 48306897 | 48306920 | 11 | - | 27260156 | HT29 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.4429515259455009 | [893] | [1611,1594,1629,1125] | 8 | hSpCas9 | negative selection | 7257687 | 48306642 | 48306665 | 11 | - | 27260156 | HT29 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.5483606679411723 | [15] | [2,14,34,0] | -7 | hSpCas9 | negative selection | 7321941 | 48306805 | 48306828 | 11 | + | 27260156 | HT29 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.4414583644085057 | [342] | [238,327,352,302] | -7 | hSpCas9 | negative selection | 7321942 | 48306791 | 48306814 | 11 | - | 27260156 | HT29 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.06795886997068251 | [609] | [952,681,667,556] | -1 | hSpCas9 | negative selection | 7321943 | 48306617 | 48306640 | 11 | - | 27260156 | MHHES1 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.48559431570929057 | [228] | [356,429,419,259] | 8 | hSpCas9 | negative selection | 7378936 | 48306818 | 48306841 | 11 | - | 27260156 | MHHES1 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.14845364447099074 | [625] | [919,687,600,412] | -3 | hSpCas9 | negative selection | 7378937 | 48306897 | 48306920 | 11 | - | 27260156 | MHHES1 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.37144478580614304 | [893] | [1366,1764,1119,1042] | 6 | hSpCas9 | negative selection | 7378938 | 48306642 | 48306665 | 11 | - | 27260156 | MHHES1 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.08877153179028241 | [15] | [16,58,0,5] | 1 | hSpCas9 | negative selection | 7443192 | 48306805 | 48306828 | 11 | + | 27260156 | MHHES1 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.3717550425541052 | [342] | [212,549,218,234] | -6 | hSpCas9 | negative selection | 7443193 | 48306791 | 48306814 | 11 | - | 27260156 | MHHES1 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.3015507497872631 | [609] | [661,714,492,409] | -5 | hSpCas9 | negative selection | 7443194 | 48306617 | 48306640 | 11 | - | 27260156 | MEWO | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.4248963727602474 | [228] | [358,208,308] | 8 | hSpCas9 | negative selection | 7500187 | 48306818 | 48306841 | 11 | - | 27260156 | MEWO | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.19743931784939325 | [625] | [587,533,424] | -4 | hSpCas9 | negative selection | 7500188 | 48306897 | 48306920 | 11 | - | 27260156 | MEWO | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.21314396922428192 | [893] | [1063,917,944] | 4 | hSpCas9 | negative selection | 7500189 | 48306642 | 48306665 | 11 | - | 27260156 | MEWO | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.6050422247984146 | [15] | [6,3,17] | -8 | hSpCas9 | negative selection | 7564443 | 48306805 | 48306828 | 11 | + | 27260156 | MEWO | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.4596083701673379 | [342] | [186,237,265] | -7 | hSpCas9 | negative selection | 7564444 | 48306791 | 48306814 | 11 | - | 27260156 | MEWO | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.23247683311082967 | [609] | [560,432,477] | -5 | hSpCas9 | negative selection | 7564445 | 48306617 | 48306640 | 11 | - | 27260156 | LNCAPCLONEFGC | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.10656184114451628 | [228] | [200,115,379,226] | 1 | hSpCas9 | negative selection | 7621438 | 48306818 | 48306841 | 11 | - | 27260156 | LNCAPCLONEFGC | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.6206196010240457 | [625] | [453,349,411,264] | -7 | hSpCas9 | negative selection | 7621439 | 48306897 | 48306920 | 11 | - | 27260156 | LNCAPCLONEFGC | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.41859533074473 | [893] | [1178,806,1308,1083] | 6 | hSpCas9 | negative selection | 7621440 | 48306642 | 48306665 | 11 | - | 27260156 | LNCAPCLONEFGC | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.7528148190843487 | [15] | [0,11,17,66] | 9 | hSpCas9 | negative selection | 7685694 | 48306805 | 48306828 | 11 | + | 27260156 | LNCAPCLONEFGC | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.45058709221129767 | [342] | [203,200,304,212] | -6 | hSpCas9 | negative selection | 7685695 | 48306791 | 48306814 | 11 | - | 27260156 | LNCAPCLONEFGC | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.276728804811451 | [609] | [329,505,473,515] | -4 | hSpCas9 | negative selection | 7685696 | 48306617 | 48306640 | 11 | - | 27260156 | PANC0327 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.20427387514178985 | [228] | [364,295,120,157] | 3 | hSpCas9 | negative selection | 7742689 | 48306818 | 48306841 | 11 | - | 27260156 | PANC0327 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.19486823806498044 | [625] | [531,506,385,518] | -3 | hSpCas9 | negative selection | 7742690 | 48306897 | 48306920 | 11 | - | 27260156 | PANC0327 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.5756639923659889 | [893] | [1421,1102,1203,1034] | 8 | hSpCas9 | negative selection | 7742691 | 48306642 | 48306665 | 11 | - | 27260156 | PANC0327 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.746661961643075 | [15] | [1,27,3,58] | 9 | hSpCas9 | negative selection | 7806945 | 48306805 | 48306828 | 11 | + | 27260156 | PANC0327 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.5049845912956182 | [342] | [281,163,289,134] | -6 | hSpCas9 | negative selection | 7806946 | 48306791 | 48306814 | 11 | - | 27260156 | PANC0327 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.5539633950347669 | [609] | [575,151,280,511] | -7 | hSpCas9 | negative selection | 7806947 | 48306617 | 48306640 | 11 | - | 27260156 | NCIH2009 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.38905444025638236 | [228] | [468,425,370] | 5 | hSpCas9 | negative selection | 7863940 | 48306818 | 48306841 | 11 | - | 27260156 | NCIH2009 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.5398795812151077 | [625] | [787,578,473] | -6 | hSpCas9 | negative selection | 7863941 | 48306897 | 48306920 | 11 | - | 27260156 | NCIH2009 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.4000875330632193 | [893] | [1930,1527,1540] | 5 | hSpCas9 | negative selection | 7863942 | 48306642 | 48306665 | 11 | - | 27260156 | NCIH2009 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.39217303020811034 | [15] | [21,19,9] | -5 | hSpCas9 | negative selection | 7928196 | 48306805 | 48306828 | 11 | + | 27260156 | NCIH2009 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -1.5396430119234665 | [342] | [162,212,116] | -9 | hSpCas9 | negative selection | 7928197 | 48306791 | 48306814 | 11 | - | 27260156 | NCIH2009 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.41592220586349515 | [609] | [672,588,660] | -5 | hSpCas9 | negative selection | 7928198 | 48306617 | 48306640 | 11 | - | 27260156 | NCIH1373 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.5673793605769797 | [228] | [182,59,372,20] | -5 | hSpCas9 | negative selection | 7985191 | 48306818 | 48306841 | 11 | - | 27260156 | NCIH1373 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.41257569107164666 | [625] | [557,698,558,67] | -4 | hSpCas9 | negative selection | 7985192 | 48306897 | 48306920 | 11 | - | 27260156 | NCIH1373 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.46512951877044906 | [893] | [1617,1440,966,406] | 4 | hSpCas9 | negative selection | 7985193 | 48306642 | 48306665 | 11 | - | 27260156 | NCIH1373 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.6624464266619192 | [15] | [0,11,25,0] | -6 | hSpCas9 | negative selection | 8049447 | 48306805 | 48306828 | 11 | + | 27260156 | NCIH1373 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -1.6078075570697958 | [342] | [122,58,155,45] | -9 | hSpCas9 | negative selection | 8049448 | 48306791 | 48306814 | 11 | - | 27260156 | NCIH1373 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.330686240254297 | [609] | [1088,298,302,157] | -3 | hSpCas9 | negative selection | 8049449 | 48306617 | 48306640 | 11 | - | 27260156 | PATU8902 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.1296826866838945 | [228] | [425,386,162,479] | 1 | hSpCas9 | negative selection | 8106442 | 48306818 | 48306841 | 11 | - | 27260156 | PATU8902 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -1.22060869204448 | [625] | [234,531,262,510] | -8 | hSpCas9 | negative selection | 8106443 | 48306897 | 48306920 | 11 | - | 27260156 | PATU8902 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.6590704370169199 | [893] | [1242,2186,2283,2074] | 7 | hSpCas9 | negative selection | 8106444 | 48306642 | 48306665 | 11 | - | 27260156 | PATU8902 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.7277708678165729 | [15] | [14,3,103,2] | 7 | hSpCas9 | negative selection | 8170698 | 48306805 | 48306828 | 11 | + | 27260156 | PATU8902 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.7625608597032795 | [342] | [216,337,109,534] | -6 | hSpCas9 | negative selection | 8170699 | 48306791 | 48306814 | 11 | - | 27260156 | PATU8902 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.9896176650284947 | [609] | [402,751,242,349] | -7 | hSpCas9 | negative selection | 8170700 | 48306617 | 48306640 | 11 | - | 27260156 | PANC1 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.3994636274548635 | [228] | [173,416,181,288] | 6 | hSpCas9 | negative selection | 8227693 | 48306818 | 48306841 | 11 | - | 27260156 | PANC1 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | 0.12306757945916552 | [625] | [569,662,508,602] | 2 | hSpCas9 | negative selection | 8227694 | 48306897 | 48306920 | 11 | - | 27260156 | PANC1 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.2581397209566231 | [893] | [835,1356,1082,538] | 4 | hSpCas9 | negative selection | 8227695 | 48306642 | 48306665 | 11 | - | 27260156 | PANC1 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.16387607545756833 | [15] | [18,18,12,0] | -3 | hSpCas9 | negative selection | 8291949 | 48306805 | 48306828 | 11 | + | 27260156 | PANC1 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.5372293800497507 | [342] | [251,243,193,136] | -7 | hSpCas9 | negative selection | 8291950 | 48306791 | 48306814 | 11 | - | 27260156 | PANC1 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.1940514901756644 | [609] | [529,619,396,329] | -3 | hSpCas9 | negative selection | 8291951 | 48306617 | 48306640 | 11 | - | 27260156 | PANC0813 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.08418965091560304 | [228] | [256,318,124,309] | -1 | hSpCas9 | negative selection | 8348944 | 48306818 | 48306841 | 11 | - | 27260156 | PANC0813 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.011613902968120426 | [625] | [926,870,540,601] | 0 | hSpCas9 | negative selection | 8348945 | 48306897 | 48306920 | 11 | - | 27260156 | PANC0813 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.32380168199769244 | [893] | [1517,1228,1320,1211] | 5 | hSpCas9 | negative selection | 8348946 | 48306642 | 48306665 | 11 | - | 27260156 | PANC0813 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -1.6761235115487523 | [15] | [11,2,1,6] | -9 | hSpCas9 | negative selection | 8413200 | 48306805 | 48306828 | 11 | + | 27260156 | PANC0813 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.6934663046218236 | [342] | [236,185,315,255] | -7 | hSpCas9 | negative selection | 8413201 | 48306791 | 48306814 | 11 | - | 27260156 | PANC0813 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.2300731625957827 | [609] | [917,321,581,646] | -4 | hSpCas9 | negative selection | 8413202 | 48306617 | 48306640 | 11 | - | 27260156 | RDES | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.31799966931825896 | [228] | [198,227,224,182] | -5 | hSpCas9 | negative selection | 8470195 | 48306818 | 48306841 | 11 | - | 27260156 | RDES | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | 0.08725936775969784 | [625] | [515,791,731,1098] | 1 | hSpCas9 | negative selection | 8470196 | 48306897 | 48306920 | 11 | - | 27260156 | RDES | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.48883544601615914 | [893] | [1223,1347,1562,1689] | 7 | hSpCas9 | negative selection | 8470197 | 48306642 | 48306665 | 11 | - | 27260156 | RDES | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.26898278036656187 | [15] | [9,16,21,45] | 4 | hSpCas9 | negative selection | 8534451 | 48306805 | 48306828 | 11 | + | 27260156 | RDES | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.7700390097175517 | [342] | [200,191,213,336] | -8 | hSpCas9 | negative selection | 8534452 | 48306791 | 48306814 | 11 | - | 27260156 | RDES | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.5576041516909271 | [609] | [430,357,636,495] | -7 | hSpCas9 | negative selection | 8534453 | 48306617 | 48306640 | 11 | - | 27260156 | PC3 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.15877711682151552 | [228] | [75,325,255,215] | -4 | hSpCas9 | negative selection | 8591446 | 48306818 | 48306841 | 11 | - | 27260156 | PC3 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | 0.1611952751189039 | [625] | [435,885,1144,524] | 3 | hSpCas9 | negative selection | 8591447 | 48306897 | 48306920 | 11 | - | 27260156 | PC3 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.3546285357254114 | [893] | [709,1217,1895,1098] | 7 | hSpCas9 | negative selection | 8591448 | 48306642 | 48306665 | 11 | - | 27260156 | PC3 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -1.357208090963569 | [15] | [1,0,32,0] | -9 | hSpCas9 | negative selection | 8655702 | 48306805 | 48306828 | 11 | + | 27260156 | PC3 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.7337394126434812 | [342] | [197,75,390,211] | -9 | hSpCas9 | negative selection | 8655703 | 48306791 | 48306814 | 11 | - | 27260156 | PC3 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.5448810726306317 | [609] | [243,327,851,457] | -8 | hSpCas9 | negative selection | 8655704 | 48306617 | 48306640 | 11 | - | 27260156 | PATU8988T | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.48312966320049044 | [228] | [263,378,241,363] | 7 | hSpCas9 | negative selection | 8712697 | 48306818 | 48306841 | 11 | - | 27260156 | PATU8988T | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.29001497035198254 | [625] | [364,728,314,602] | -5 | hSpCas9 | negative selection | 8712698 | 48306897 | 48306920 | 11 | - | 27260156 | PATU8988T | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.42094642388703274 | [893] | [904,1061,1200,1473] | 7 | hSpCas9 | negative selection | 8712699 | 48306642 | 48306665 | 11 | - | 27260156 | PATU8988T | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -1.1621420873836987 | [15] | [0,5,17,1] | -9 | hSpCas9 | negative selection | 8776953 | 48306805 | 48306828 | 11 | + | 27260156 | PATU8988T | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -1.0154795053896337 | [342] | [132,142,233,140] | -9 | hSpCas9 | negative selection | 8776954 | 48306791 | 48306814 | 11 | - | 27260156 | PATU8988T | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.0016691966432527128 | [609] | [651,702,569,427] | 0 | hSpCas9 | negative selection | 8776955 | 48306617 | 48306640 | 11 | - | 27260156 | T47D | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.038441929627123894 | [228] | [223,278,231,303] | -1 | hSpCas9 | negative selection | 8833948 | 48306818 | 48306841 | 11 | - | 27260156 | T47D | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.4550223578883153 | [625] | [597,472,434,631] | -7 | hSpCas9 | negative selection | 8833949 | 48306897 | 48306920 | 11 | - | 27260156 | T47D | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.32013650017783546 | [893] | [1286,1242,1238,1441] | 6 | hSpCas9 | negative selection | 8833950 | 48306642 | 48306665 | 11 | - | 27260156 | T47D | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 1.0694819784910923 | [15] | [22,59,25,45] | 9 | hSpCas9 | negative selection | 8898204 | 48306805 | 48306828 | 11 | + | 27260156 | T47D | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.9807833560637579 | [342] | [239,163,191,217] | -9 | hSpCas9 | negative selection | 8898205 | 48306791 | 48306814 | 11 | - | 27260156 | T47D | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.5696226970104156 | [609] | [374,512,496,527] | -8 | hSpCas9 | negative selection | 8898206 | 48306617 | 48306640 | 11 | - | 27260156 | SU8686 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.18668820754232685 | [228] | [167,191,243,197] | -3 | hSpCas9 | negative selection | 8955199 | 48306818 | 48306841 | 11 | - | 27260156 | SU8686 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.021212954188391697 | [625] | [476,633,682,671] | 0 | hSpCas9 | negative selection | 8955200 | 48306897 | 48306920 | 11 | - | 27260156 | SU8686 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.15788293502166717 | [893] | [888,798,1025,1325] | 2 | hSpCas9 | negative selection | 8955201 | 48306642 | 48306665 | 11 | - | 27260156 | SU8686 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.8728180718849616 | [15] | [21,5,2,0] | -8 | hSpCas9 | negative selection | 9019455 | 48306805 | 48306828 | 11 | + | 27260156 | SU8686 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.5741329862168659 | [342] | [195,254,240,218] | -7 | hSpCas9 | negative selection | 9019456 | 48306791 | 48306814 | 11 | - | 27260156 | SU8686 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.442609331706084 | [609] | [541,416,417,380] | -6 | hSpCas9 | negative selection | 9019457 | 48306617 | 48306640 | 11 | - | 27260156 | SKES1 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.021736286779467928 | [228] | [395,204,138,184] | 0 | hSpCas9 | negative selection | 9076450 | 48306818 | 48306841 | 11 | - | 27260156 | SKES1 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.006281914275408196 | [625] | [760,717,599,452] | 0 | hSpCas9 | negative selection | 9076451 | 48306897 | 48306920 | 11 | - | 27260156 | SKES1 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.35815590795008434 | [893] | [1249,942,1255,1104] | 7 | hSpCas9 | negative selection | 9076452 | 48306642 | 48306665 | 11 | - | 27260156 | SKES1 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | -0.8783208764658683 | [15] | [17,12,0,4] | -9 | hSpCas9 | negative selection | 9140706 | 48306805 | 48306828 | 11 | + | 27260156 | SKES1 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -1.1389354035906143 | [342] | [155,204,156,112] | -9 | hSpCas9 | negative selection | 9140707 | 48306791 | 48306814 | 11 | - | 27260156 | SKES1 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.35094357522923303 | [609] | [552,627,393,370] | -6 | hSpCas9 | negative selection | 9140708 | 48306617 | 48306640 | 11 | - | 27260156 | TOV112D | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | -0.017191903542207232 | [228] | [166,102,383,216] | 0 | hSpCas9 | negative selection | 9197701 | 48306818 | 48306841 | 11 | - | 27260156 | TOV112D | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.47506878202797964 | [625] | [422,796,313,354] | -7 | hSpCas9 | negative selection | 9197702 | 48306897 | 48306920 | 11 | - | 27260156 | TOV112D | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.04866229855860127 | [893] | [901,1054,828,945] | 1 | hSpCas9 | negative selection | 9197703 | 48306642 | 48306665 | 11 | - | 27260156 | TOV112D | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.37970174480396235 | [15] | [13,45,8,19] | 7 | hSpCas9 | negative selection | 9261957 | 48306805 | 48306828 | 11 | + | 27260156 | TOV112D | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.6828807849934603 | [342] | [254,253,148,210] | -8 | hSpCas9 | negative selection | 9261958 | 48306791 | 48306814 | 11 | - | 27260156 | TOV112D | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.32132458309181067 | [609] | [517,850,348,332] | -6 | hSpCas9 | negative selection | 9261959 | 48306617 | 48306640 | 11 | - | 27260156 | TC71 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.024458148751574926 | [228] | [308,260,215,209] | 0 | hSpCas9 | negative selection | 9318952 | 48306818 | 48306841 | 11 | - | 27260156 | TC71 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.14941952655996438 | [625] | [587,663,521,651] | -4 | hSpCas9 | negative selection | 9318953 | 48306897 | 48306920 | 11 | - | 27260156 | TC71 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.1446558340735572 | [893] | [988,1124,1003,1126] | 3 | hSpCas9 | negative selection | 9318954 | 48306642 | 48306665 | 11 | - | 27260156 | TC71 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.37704076947716025 | [15] | [27,6,37,14] | 8 | hSpCas9 | negative selection | 9383208 | 48306805 | 48306828 | 11 | + | 27260156 | TC71 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.5049071352111763 | [342] | [246,259,292,233] | -8 | hSpCas9 | negative selection | 9383209 | 48306791 | 48306814 | 11 | - | 27260156 | TC71 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.10250428946019896 | [609] | [659,641,562,568] | -3 | hSpCas9 | negative selection | 9383210 | 48306617 | 48306640 | 11 | - | 27260156 | TC32 | viability | ACACTTCCGGCAATCCATGATGG | OR4S1 | ENSG00000176555 | 0.041017750776360384 | [228] | [179,102,242,412] | 0 | hSpCas9 | negative selection | 9440203 | 48306818 | 48306841 | 11 | - | 27260156 | TC32 | viability | TAAAGAAATCATACCGCTGTTGG | OR4S1 | ENSG00000176555 | -0.18046906487881303 | [625] | [503,319,728,612] | -3 | hSpCas9 | negative selection | 9440204 | 48306897 | 48306920 | 11 | - | 27260156 | TC32 | viability | TACGCCGGTCCTCAGATGACTGG | OR4S1 | ENSG00000176555 | 0.4034149245843671 | [893] | [1027,732,1410,1432] | 7 | hSpCas9 | negative selection | 9440205 | 48306642 | 48306665 | 11 | - | 27260156 | TC32 | viability | ACCAGGAGGCCCCCGCTAGCAGG | OR4S1 | ENSG00000176555 | 0.43675356839699475 | [15] | [17,23,14,20] | 7 | hSpCas9 | negative selection | 9504459 | 48306805 | 48306828 | 11 | + | 27260156 | TC32 | viability | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.5491847969858149 | [342] | [246,192,298,143] | -8 | hSpCas9 | negative selection | 9504460 | 48306791 | 48306814 | 11 | - | 27260156 | TC32 | viability | CACGATGAGACCTACCATGTAGG | OR4S1 | ENSG00000176555 | -0.20006322764241 | [609] | [444,368,712,534] | -4 | hSpCas9 | negative selection | 9504461 | 48306805 | 48306828 | 11 | + | 27869803 | HPAFII | viability after 27 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.7518168482035017 | [692] | [223,209,NaN] | -5 | hSpCas9 | negative selection | 9541831 | 48306977 | 48307000 | 11 | - | 27869803 | HPAFII | viability after 27 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 1.2852646380772157 | [241] | [98,485,NaN] | 9 | hSpCas9 | negative selection | 9541832 | 48306990 | 48307013 | 11 | + | 27869803 | HPAFII | viability after 27 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | 0.6248380100240246 | [145] | [161,81,NaN] | 5 | hSpCas9 | negative selection | 9541833 | 48307004 | 48307027 | 11 | - | 27869803 | HPAFII | viability after 27 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -0.7909383855787248 | [218] | [41,86,NaN] | -5 | hSpCas9 | negative selection | 9541834 | 48307007 | 48307030 | 11 | - | 27869803 | HPAFII | viability after 27 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 1.3796394991450094 | [166] | [312,157,NaN] | 9 | hSpCas9 | negative selection | 9541835 | 48306805 | 48306828 | 11 | + | 27869803 | HPAFII | viability after 15 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.49143375343659457 | [692] | [678,436,NaN] | -5 | hSpCas9 | negative selection | 9624280 | 48306977 | 48307000 | 11 | - | 27869803 | HPAFII | viability after 15 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 0.8861225960967367 | [241] | [365,551,NaN] | 8 | hSpCas9 | negative selection | 9624281 | 48306990 | 48307013 | 11 | + | 27869803 | HPAFII | viability after 15 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | 0.8642353815321974 | [145] | [313,267,NaN] | 8 | hSpCas9 | negative selection | 9624282 | 48307004 | 48307027 | 11 | - | 27869803 | HPAFII | viability after 15 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -1.2726341037460214 | [218] | [118,83,NaN] | -8 | hSpCas9 | negative selection | 9624283 | 48307007 | 48307030 | 11 | - | 27869803 | HPAFII | viability after 15 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.7344464101328447 | [166] | [416,224,NaN] | 7 | hSpCas9 | negative selection | 9624284 | 48306805 | 48306828 | 11 | + | 27869803 | ASPC1 | viability after 36 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -0.30049030737470694 | [2125] | [1058,579,293] | -3 | hSpCas9 | negative selection | 9706729 | 48306977 | 48307000 | 11 | - | 27869803 | ASPC1 | viability after 36 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | -0.27925402487306206 | [801] | [395,288,65] | -3 | hSpCas9 | negative selection | 9706730 | 48306990 | 48307013 | 11 | + | 27869803 | ASPC1 | viability after 36 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.03889011501261347 | [564] | [211,337,59] | 0 | hSpCas9 | negative selection | 9706731 | 48307004 | 48307027 | 11 | - | 27869803 | ASPC1 | viability after 36 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | 0.21564296050485227 | [564] | [345,298,88] | 2 | hSpCas9 | negative selection | 9706732 | 48307007 | 48307030 | 11 | - | 27869803 | ASPC1 | viability after 36 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.546483635005656 | [407] | [328,280,62] | 5 | hSpCas9 | negative selection | 9706733 | 48306805 | 48306828 | 11 | + | 27869803 | PATU8988S | viability after 35 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 0.3656937962383464 | [1579] | [1008,629,NaN] | 4 | hSpCas9 | negative selection | 9789178 | 48306977 | 48307000 | 11 | - | 27869803 | PATU8988S | viability after 35 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 0.378541595798911 | [555] | [340,240,NaN] | 4 | hSpCas9 | negative selection | 9789179 | 48306990 | 48307013 | 11 | + | 27869803 | PATU8988S | viability after 35 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | 0.38996132527062566 | [582] | [384,229,NaN] | 4 | hSpCas9 | negative selection | 9789180 | 48307004 | 48307027 | 11 | - | 27869803 | PATU8988S | viability after 35 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | 0.8130304429529315 | [535] | [496,260,NaN] | 8 | hSpCas9 | negative selection | 9789181 | 48307007 | 48307030 | 11 | - | 27869803 | PATU8988S | viability after 35 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | -0.16379514004425083 | [402] | [95,193,NaN] | -2 | hSpCas9 | negative selection | 9789182 | 48306805 | 48306828 | 11 | + | 27869803 | PATU8988S | viability after 31 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | 0.36382827939459395 | [1579] | [837,775,NaN] | 4 | hSpCas9 | negative selection | 9871627 | 48306977 | 48307000 | 11 | - | 27869803 | PATU8988S | viability after 31 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 0.7137201122856153 | [555] | [345,385,NaN] | 8 | hSpCas9 | negative selection | 9871628 | 48306990 | 48307013 | 11 | + | 27869803 | PATU8988S | viability after 31 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | -0.051705546039964426 | [582] | [240,202,NaN] | 0 | hSpCas9 | negative selection | 9871629 | 48307004 | 48307027 | 11 | - | 27869803 | PATU8988S | viability after 31 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | 0.7769445938305013 | [535] | [462,242,NaN] | 8 | hSpCas9 | negative selection | 9871630 | 48307007 | 48307030 | 11 | - | 27869803 | PATU8988S | viability after 31 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 0.42661264303578705 | [402] | [138,313,NaN] | 5 | hSpCas9 | negative selection | 9871631 | 48306805 | 48306828 | 11 | + | 27869803 | HPAFII | viability after 35 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -1.5933031026315527 | [692] | [64,173,NaN] | -7 | hSpCas9 | negative selection | 9954076 | 48306977 | 48307000 | 11 | - | 27869803 | HPAFII | viability after 35 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 1.1613406422947066 | [241] | [67,505,NaN] | 7 | hSpCas9 | negative selection | 9954077 | 48306990 | 48307013 | 11 | + | 27869803 | HPAFII | viability after 35 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | 0.7611015063105969 | [145] | [184,57,NaN] | 5 | hSpCas9 | negative selection | 9954078 | 48307004 | 48307027 | 11 | - | 27869803 | HPAFII | viability after 35 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -1.1781050417125927 | [218] | [40,57,NaN] | -6 | hSpCas9 | negative selection | 9954079 | 48307007 | 48307030 | 11 | - | 27869803 | HPAFII | viability after 35 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 1.5089766316806084 | [166] | [297,175,NaN] | 8 | hSpCas9 | negative selection | 9954080 | 48306805 | 48306828 | 11 | + | 27869803 | HPAFII | viability after 31 days | CTCATCGTGGTGGCCAACAGCGG | OR4S1 | ENSG00000176555 | -1.0338101907720596 | [692] | [121,263,NaN] | -6 | hSpCas9 | negative selection | 10036525 | 48306977 | 48307000 | 11 | - | 27869803 | HPAFII | viability after 31 days | GGGACGAATGTACATGAACATGG | OR4S1 | ENSG00000176555 | 1.1649417429493252 | [241] | [92,534,NaN] | 8 | hSpCas9 | negative selection | 10036526 | 48306990 | 48307013 | 11 | + | 27869803 | HPAFII | viability after 31 days | CATTCGTCCCTCCACCACCCTGG | OR4S1 | ENSG00000176555 | 1.11190885422165 | [145] | [167,186,NaN] | 7 | hSpCas9 | negative selection | 10036527 | 48307004 | 48307027 | 11 | - | 27869803 | HPAFII | viability after 31 days | AAGTTTGTCAGCAGCCAGGGTGG | OR4S1 | ENSG00000176555 | -0.6597176098270858 | [218] | [50,106,NaN] | -4 | hSpCas9 | negative selection | 10036528 | 48307007 | 48307030 | 11 | - | 27869803 | HPAFII | viability after 31 days | GATAAGTTTGTCAGCAGCCAGGG | OR4S1 | ENSG00000176555 | 1.5022737709091665 | [166] | [287,240,NaN] | 9 | hSpCas9 | negative selection | 10036529 |