| 20640886 | 20640909 | 14 | - | 26627737 | DLD1 | viability | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 0.5791817198361289 | [467] | [218,190,240] | 6 | hSpCas9 | negative selection | 787879 | 20641053 | 20641076 | 14 | + | 26627737 | DLD1 | viability | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 0.031239357428700876 | [198] | [30,107,54] | 0 | hSpCas9 | negative selection | 787880 | 20641386 | 20641409 | 14 | + | 26627737 | DLD1 | viability | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.009789949986803048 | [1123] | [207,383,454] | 0 | hSpCas9 | negative selection | 787881 | 20641610 | 20641633 | 14 | - | 26627737 | DLD1 | viability | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.8862372293650203 | [372] | [255,244,155] | 8 | hSpCas9 | negative selection | 787882 | 20641638 | 20641661 | 14 | - | 26627737 | DLD1 | viability | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.9810233181657033 | [1154] | [170,152,217] | -7 | hSpCas9 | negative selection | 787883 | 20640886 | 20640909 | 14 | - | 26627737 | GBM cells | viability after 5 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 0.2959848276350804 | [201] | [106,158] | 4 | hSpCas9 | negative selection | 870194 | 20641053 | 20641076 | 14 | + | 26627737 | GBM cells | viability after 5 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 0.0038834344872279436 | [158] | [89,80] | 0 | hSpCas9 | negative selection | 870195 | 20641386 | 20641409 | 14 | + | 26627737 | GBM cells | viability after 5 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.21743008635178251 | [554] | [238,272] | -3 | hSpCas9 | negative selection | 870196 | 20641610 | 20641633 | 14 | - | 26627737 | GBM cells | viability after 5 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.18385706067241114 | [402] | [235,254] | 3 | hSpCas9 | negative selection | 870197 | 20641638 | 20641661 | 14 | - | 26627737 | GBM cells | viability after 5 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.7075817873851119 | [404] | [119,145] | -8 | hSpCas9 | negative selection | 870198 | 20640886 | 20640909 | 14 | - | 26627737 | GBM cells | viability after 13 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 0.5445594792822107 | [201] | [155,162] | 6 | hSpCas9 | negative selection | 952509 | 20641053 | 20641076 | 14 | + | 26627737 | GBM cells | viability after 13 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -0.07971069519466467 | [158] | [106,60] | -1 | hSpCas9 | negative selection | 952510 | 20641386 | 20641409 | 14 | + | 26627737 | GBM cells | viability after 13 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.21219946315235472 | [554] | [281,241] | -3 | hSpCas9 | negative selection | 952511 | 20641610 | 20641633 | 14 | - | 26627737 | GBM cells | viability after 13 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.35356418127659883 | [402] | [285,273] | 4 | hSpCas9 | negative selection | 952512 | 20641638 | 20641661 | 14 | - | 26627737 | GBM cells | viability after 13 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.6686160369344586 | [404] | [140,135] | -7 | hSpCas9 | negative selection | 952513 | 20640886 | 20640909 | 14 | - | 26627737 | GBM cells | viability after 21 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 0.5284379954838798 | [201] | [174,142] | 5 | hSpCas9 | negative selection | 1034824 | 20641053 | 20641076 | 14 | + | 26627737 | GBM cells | viability after 21 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -0.16025314663121204 | [158] | [81,72] | -1 | hSpCas9 | negative selection | 1034825 | 20641386 | 20641409 | 14 | + | 26627737 | GBM cells | viability after 21 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.2987325762984767 | [554] | [396,346] | 3 | hSpCas9 | negative selection | 1034826 | 20641610 | 20641633 | 14 | - | 26627737 | GBM cells | viability after 21 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.7611318688107798 | [402] | [392,350] | 7 | hSpCas9 | negative selection | 1034827 | 20641638 | 20641661 | 14 | - | 26627737 | GBM cells | viability after 21 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.13712766937455267 | [404] | [209,190] | -1 | hSpCas9 | negative selection | 1034828 | 20640886 | 20640909 | 14 | - | 26627737 | RPE1 | viability after 9 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 1.9858744950866085 | [484] | [290,1001] | 8 | hSpCas9 | negative selection | 1117139 | 20641053 | 20641076 | 14 | + | 26627737 | RPE1 | viability after 9 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -0.09926115784293743 | [259] | [99,44] | 0 | hSpCas9 | negative selection | 1117140 | 20641386 | 20641409 | 14 | + | 26627737 | RPE1 | viability after 9 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.03531285461831479 | [1567] | [344,706] | 0 | hSpCas9 | negative selection | 1117141 | 20641610 | 20641633 | 14 | - | 26627737 | RPE1 | viability after 9 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 1.3045442572699344 | [688] | [310,818] | 7 | hSpCas9 | negative selection | 1117142 | 20641638 | 20641661 | 14 | - | 26627737 | RPE1 | viability after 9 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | 0.1352120508604654 | [1310] | [300,643] | 1 | hSpCas9 | negative selection | 1117143 | 20640886 | 20640909 | 14 | - | 26627737 | RPE1 | viability after 12 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 2.0295529100998375 | [484] | [412,657] | 8 | hSpCas9 | negative selection | 1199454 | 20641053 | 20641076 | 14 | + | 26627737 | RPE1 | viability after 12 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -0.20297136749612954 | [259] | [66,53] | -1 | hSpCas9 | negative selection | 1199455 | 20641386 | 20641409 | 14 | + | 26627737 | RPE1 | viability after 12 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.09655610018366034 | [1567] | [396,506] | 0 | hSpCas9 | negative selection | 1199456 | 20641610 | 20641633 | 14 | - | 26627737 | RPE1 | viability after 12 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 1.3316719953204088 | [688] | [360,576] | 7 | hSpCas9 | negative selection | 1199457 | 20641638 | 20641661 | 14 | - | 26627737 | RPE1 | viability after 12 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.4781618356358611 | [1310] | [230,275] | -3 | hSpCas9 | negative selection | 1199458 | 20640886 | 20640909 | 14 | - | 26627737 | RPE1 | viability after 15 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 2.4884911579610813 | [484] | [801,738] | 9 | hSpCas9 | negative selection | 1281769 | 20641053 | 20641076 | 14 | + | 26627737 | RPE1 | viability after 15 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 0.6933208384769457 | [259] | [122,114] | 4 | hSpCas9 | negative selection | 1281770 | 20641386 | 20641409 | 14 | + | 26627737 | RPE1 | viability after 15 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.4469668927478325 | [1567] | [624,584] | 3 | hSpCas9 | negative selection | 1281771 | 20641610 | 20641633 | 14 | - | 26627737 | RPE1 | viability after 15 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.9949746428550881 | [688] | [334,439] | 6 | hSpCas9 | negative selection | 1281772 | 20641638 | 20641661 | 14 | - | 26627737 | RPE1 | viability after 15 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.3454599177077686 | [1310] | [185,393] | -2 | hSpCas9 | negative selection | 1281773 | 20640886 | 20640909 | 14 | - | 26627737 | RPE1 | viability after 18 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 1.7028418662557887 | [484] | [282,578] | 8 | hSpCas9 | negative selection | 1364084 | 20641053 | 20641076 | 14 | + | 26627737 | RPE1 | viability after 18 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 0.7181908559696804 | [259] | [127,101] | 4 | hSpCas9 | negative selection | 1364085 | 20641386 | 20641409 | 14 | + | 26627737 | RPE1 | viability after 18 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.45882306494395886 | [1567] | [525,640] | 3 | hSpCas9 | negative selection | 1364086 | 20641610 | 20641633 | 14 | - | 26627737 | RPE1 | viability after 18 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.9952190214915211 | [688] | [272,474] | 6 | hSpCas9 | negative selection | 1364087 | 20641638 | 20641661 | 14 | - | 26627737 | RPE1 | viability after 18 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -1.273684656373241 | [1310] | [155,135] | -7 | hSpCas9 | negative selection | 1364088 | 20640886 | 20640909 | 14 | - | 26627737 | HeLa | viability after 8 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | -0.5748054295636341 | [563] | [262,118,135] | -5 | hSpCas9 | negative selection | 1446399 | 20641053 | 20641076 | 14 | + | 26627737 | HeLa | viability after 8 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -0.587203004965724 | [136] | [71,26,27] | -5 | hSpCas9 | negative selection | 1446400 | 20641386 | 20641409 | 14 | + | 26627737 | HeLa | viability after 8 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.6302811188921067 | [646] | [406,413,476] | 5 | hSpCas9 | negative selection | 1446401 | 20641610 | 20641633 | 14 | - | 26627737 | HeLa | viability after 8 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | -0.3605992450132141 | [471] | [210,73,202] | -4 | hSpCas9 | negative selection | 1446402 | 20641638 | 20641661 | 14 | - | 26627737 | HeLa | viability after 8 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.2948514594667313 | [324] | [102,196,47] | -3 | hSpCas9 | negative selection | 1446403 | 20640886 | 20640909 | 14 | - | 26627737 | HeLa | viability after 12 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | -0.39648826620153155 | [563] | [78,189,257] | -4 | hSpCas9 | negative selection | 1528714 | 20641053 | 20641076 | 14 | + | 26627737 | HeLa | viability after 12 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 0.4862489484495627 | [136] | [4,95,132] | 4 | hSpCas9 | negative selection | 1528715 | 20641386 | 20641409 | 14 | + | 26627737 | HeLa | viability after 12 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 1.0596409654237757 | [646] | [568,503,604] | 7 | hSpCas9 | negative selection | 1528716 | 20641610 | 20641633 | 14 | - | 26627737 | HeLa | viability after 12 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | -0.02356524352199807 | [471] | [237,163,177] | 0 | hSpCas9 | negative selection | 1528717 | 20641638 | 20641661 | 14 | - | 26627737 | HeLa | viability after 12 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | 0.6448430694471966 | [324] | [208,190,231] | 5 | hSpCas9 | negative selection | 1528718 | 20640886 | 20640909 | 14 | - | 26627737 | HeLa | viability after 15 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | -0.8081228538522378 | [563] | [134,58,204] | -6 | hSpCas9 | negative selection | 1611029 | 20641053 | 20641076 | 14 | + | 26627737 | HeLa | viability after 15 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 1.2578558875744454 | [136] | [89,88,228] | 8 | hSpCas9 | negative selection | 1611030 | 20641386 | 20641409 | 14 | + | 26627737 | HeLa | viability after 15 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.5741591524257441 | [646] | [329,457,388] | 4 | hSpCas9 | negative selection | 1611031 | 20641610 | 20641633 | 14 | - | 26627737 | HeLa | viability after 15 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | -0.44650635177196896 | [471] | [148,155,115] | -4 | hSpCas9 | negative selection | 1611032 | 20641638 | 20641661 | 14 | - | 26627737 | HeLa | viability after 15 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.29035258979105505 | [324] | [21,94,216] | -3 | hSpCas9 | negative selection | 1611033 | 20640886 | 20640909 | 14 | - | 26627737 | HeLa | viability after 18 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | -0.8638411505352395 | [563] | [83,44,204] | -6 | hSpCas9 | negative selection | 1693344 | 20641053 | 20641076 | 14 | + | 26627737 | HeLa | viability after 18 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 1.2436475632423172 | [136] | [55,75,228] | 8 | hSpCas9 | negative selection | 1693345 | 20641386 | 20641409 | 14 | + | 26627737 | HeLa | viability after 18 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.59889679558215 | [646] | [225,389,388] | 5 | hSpCas9 | negative selection | 1693346 | 20641610 | 20641633 | 14 | - | 26627737 | HeLa | viability after 18 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | -0.4313937024210056 | [471] | [98,133,115] | -4 | hSpCas9 | negative selection | 1693347 | 20641638 | 20641661 | 14 | - | 26627737 | HeLa | viability after 18 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.27461104114041046 | [324] | [15,79,216] | -2 | hSpCas9 | negative selection | 1693348 | 20640886 | 20640909 | 14 | - | 26627737 | HCT116 | viability after 6 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | -1.1542320218832647 | [633] | [18,58] | -6 | hSpCas9 | negative selection | 1775659 | 20641053 | 20641076 | 14 | + | 26627737 | HCT116 | viability after 6 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -4.751626976816284 | [414] | [4,0] | -9 | hSpCas9 | negative selection | 1775660 | 20641386 | 20641409 | 14 | + | 26627737 | HCT116 | viability after 6 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.6012043261664038 | [957] | [241,220] | 3 | hSpCas9 | negative selection | 1775661 | 20641610 | 20641633 | 14 | - | 26627737 | HCT116 | viability after 6 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | -0.30453952633937886 | [585] | [120,48] | -2 | hSpCas9 | negative selection | 1775662 | 20641638 | 20641661 | 14 | - | 26627737 | HCT116 | viability after 6 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | 0.6873975323806263 | [610] | [193,132] | 4 | hSpCas9 | negative selection | 1775663 | 20640886 | 20640909 | 14 | - | 26627737 | HCT116 | viability after 8 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 1.1531481309207174 | [140] | [110,210,194] | 8 | hSpCas9 | negative selection | 1857974 | 20641053 | 20641076 | 14 | + | 26627737 | HCT116 | viability after 8 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -0.5410345645776606 | [134] | [31,66,53] | -6 | hSpCas9 | negative selection | 1857975 | 20641386 | 20641409 | 14 | + | 26627737 | HCT116 | viability after 8 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.33543006588563284 | [782] | [312,260,449] | -4 | hSpCas9 | negative selection | 1857976 | 20641610 | 20641633 | 14 | - | 26627737 | HCT116 | viability after 8 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.07729343431536645 | [320] | [228,177,153] | 0 | hSpCas9 | negative selection | 1857977 | 20641638 | 20641661 | 14 | - | 26627737 | HCT116 | viability after 8 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.08180275866608527 | [394] | [236,130,248] | -1 | hSpCas9 | negative selection | 1857978 | 20640886 | 20640909 | 14 | - | 26627737 | HCT116 | viability after 9 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | -0.842138691498129 | [633] | [75,108] | -5 | hSpCas9 | negative selection | 1940289 | 20641053 | 20641076 | 14 | + | 26627737 | HCT116 | viability after 9 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -0.12120983723652412 | [414] | [102,100] | -1 | hSpCas9 | negative selection | 1940290 | 20641386 | 20641409 | 14 | + | 26627737 | HCT116 | viability after 9 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.67059957368004 | [957] | [395,415] | 5 | hSpCas9 | negative selection | 1940291 | 20641610 | 20641633 | 14 | - | 26627737 | HCT116 | viability after 9 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.6040673997142928 | [585] | [143,311] | 4 | hSpCas9 | negative selection | 1940292 | 20641638 | 20641661 | 14 | - | 26627737 | HCT116 | viability after 9 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.362582681553074 | [610] | [208,61] | -3 | hSpCas9 | negative selection | 1940293 | 20640886 | 20640909 | 14 | - | 26627737 | HCT116 | viability after 12 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 1.2564165866965058 | [140] | [215,108,200] | 8 | hSpCas9 | negative selection | 2022604 | 20641053 | 20641076 | 14 | + | 26627737 | HCT116 | viability after 12 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 0.5543922485318636 | [134] | [38,50,226] | 5 | hSpCas9 | negative selection | 2022605 | 20641386 | 20641409 | 14 | + | 26627737 | HCT116 | viability after 12 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.6088373907624135 | [782] | [314,207,280] | -6 | hSpCas9 | negative selection | 2022606 | 20641610 | 20641633 | 14 | - | 26627737 | HCT116 | viability after 12 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.13785325816450658 | [320] | [183,186,185] | 1 | hSpCas9 | negative selection | 2022607 | 20641638 | 20641661 | 14 | - | 26627737 | HCT116 | viability after 12 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | 0.7532640515201952 | [394] | [342,171,530] | 6 | hSpCas9 | negative selection | 2022608 | 20640886 | 20640909 | 14 | - | 26627737 | HCT116 | viability after 15 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 1.1141572275386662 | [140] | [265,186,84] | 8 | hSpCas9 | negative selection | 2104919 | 20641053 | 20641076 | 14 | + | 26627737 | HCT116 | viability after 15 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 0.5642783626451925 | [134] | [90,48,199] | 5 | hSpCas9 | negative selection | 2104920 | 20641386 | 20641409 | 14 | + | 26627737 | HCT116 | viability after 15 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.5272191095061342 | [782] | [342,297,298] | -5 | hSpCas9 | negative selection | 2104921 | 20641610 | 20641633 | 14 | - | 26627737 | HCT116 | viability after 15 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.5319590391980689 | [320] | [260,273,263] | 5 | hSpCas9 | negative selection | 2104922 | 20641638 | 20641661 | 14 | - | 26627737 | HCT116 | viability after 15 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | 0.16182312910925323 | [394] | [263,197,299] | 1 | hSpCas9 | negative selection | 2104923 | 20640886 | 20640909 | 14 | - | 26627737 | HCT116 | viability after 18 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 1.5254254545796357 | [140] | [225,189,171] | 9 | hSpCas9 | negative selection | 2187234 | 20641053 | 20641076 | 14 | + | 26627737 | HCT116 | viability after 18 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 0.6324589558182685 | [134] | [104,86,112] | 5 | hSpCas9 | negative selection | 2187235 | 20641386 | 20641409 | 14 | + | 26627737 | HCT116 | viability after 18 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | 0.19103862650165215 | [782] | [543,483,256] | 1 | hSpCas9 | negative selection | 2187236 | 20641610 | 20641633 | 14 | - | 26627737 | HCT116 | viability after 18 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.2445299672178687 | [320] | [127,202,220] | 2 | hSpCas9 | negative selection | 2187237 | 20641638 | 20641661 | 14 | - | 26627737 | HCT116 | viability after 18 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | 0.08283545278389132 | [394] | [247,69,301] | 0 | hSpCas9 | negative selection | 2187238 | 20641268 | 20641291 | 14 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | ACAGCCCCACTCATGAGCAAGGG | OR6S1 | ENSG00000181803 | -0.4465089795178513 | [2,3] | [3,0] | -6 | hSpCas9 | positive selection | 3008740 | 20641535 | 20641558 | 14 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GTTGATTGTGGGGGTGGTAAGGG | OR6S1 | ENSG00000181803 | 0.09873326761976364 | [2,2] | [2,1] | 2 | hSpCas9 | positive selection | 3008741 | 20641268 | 20641291 | 14 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | ACAGCCCCACTCATGAGCAAGGG | OR6S1 | ENSG00000181803 | 0.06681771790954169 | [2,2] | [3,1] | 1 | hSpCas9 | positive selection | 3076598 | 20641535 | 20641558 | 14 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GTTGATTGTGGGGGTGGTAAGGG | OR6S1 | ENSG00000181803 | -0.19717242985569372 | [2,2] | [2,0] | -3 | hSpCas9 | positive selection | 3076599 | 20641612 | 20641635 | | + | 24336571 | A375 | resistance to PLX after 7 days | ACTCTTGCGCTGTTGAGATTTGG | OR6S1 | ENSG00000181803 | -0.07691894734474092 | [19,19] | [18,17] | -2 | hSpCas9 | positive selection | 3133173 | 20641313 | 20641336 | | - | 24336571 | A375 | resistance to PLX after 7 days | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.021118012822609833 | [19,19] | [18,21] | 0 | hSpCas9 | positive selection | 3133174 | 20641612 | 20641635 | | + | 24336571 | A375 | resistance to PLX after 14 days | ACTCTTGCGCTGTTGAGATTTGG | OR6S1 | ENSG00000181803 | -1.3928408786179967 | [28,20] | [4,2] | -9 | hSpCas9 | positive selection | 3190966 | 20641313 | 20641336 | | - | 24336571 | A375 | resistance to PLX after 14 days | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.3066755968856956 | [21,14] | [5,6] | -3 | hSpCas9 | positive selection | 3190967 | 20641612 | 20641635 | | + | 24336571 | A375 | viability after 7 days | ACTCTTGCGCTGTTGAGATTTGG | OR6S1 | ENSG00000181803 | 0.5195789077185946 | [13] | [19,19] | 7 | hSpCas9 | negative selection | 3248759 | 20641313 | 20641336 | | - | 24336571 | A375 | viability after 7 days | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.39548340765748874 | [15] | [19,19] | 6 | hSpCas9 | negative selection | 3248760 | 20641612 | 20641635 | | + | 24336571 | A375 | viability after 14 days | ACTCTTGCGCTGTTGAGATTTGG | OR6S1 | ENSG00000181803 | 0.8560379970041188 | [13] | [28,20] | 9 | hSpCas9 | negative selection | 3306552 | 20641313 | 20641336 | | - | 24336571 | A375 | viability after 14 days | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.29309941170876735 | [15] | [21,14] | 4 | hSpCas9 | negative selection | 3306553 | 20641639 | 20641662 | 14 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | 0.06750165256581787 | [145,145] | [0,0] | 0 | hSpCas9 | positive selection | 3383986 | 20641340 | 20641363 | 14 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | 0.3746831620839938 | [117,117] | [0,0] | 2 | hSpCas9 | positive selection | 3383987 | 20641273 | 20641296 | 14 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 1.5294057568826358 | [264,264] | [4,4] | 6 | hSpCas9 | positive selection | 3383988 | 20641267 | 20641290 | 14 | + | 26780180 | HT29 | viability (Avana library 4 designs) | ACAGCCCCACTCATGAGCAAGGG | OR6S1 | ENSG00000181803 | 0.813367967578733 | [] | [] | 3 | hSpCas9 | negative selection | 3446731 | 20641652 | 20641675 | 14 | + | 26780180 | HT29 | viability (Avana library 4 designs) | ACTCTGTTGGATCACTACTGTGG | OR6S1 | ENSG00000181803 | 1.02790590560839 | [] | [] | 4 | hSpCas9 | negative selection | 3446732 | 20641564 | 20641587 | 14 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GTCTATCTCCTGAATCTGACAGG | OR6S1 | ENSG00000181803 | -0.0963217883065366 | [] | [] | -1 | hSpCas9 | negative selection | 3446733 | 20641535 | 20641558 | 14 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GTTGATTGTGGGGGTGGTAAGGG | OR6S1 | ENSG00000181803 | 0.556827305319141 | [] | [] | 2 | hSpCas9 | negative selection | 3446734 | 20641652 | 20641675 | 14 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ACTCTGTTGGATCACTACTGTGG | OR6S1 | ENSG00000181803 | 2.2747382075039 | [] | [] | 3 | hSpCas9 | negative selection | 3540199 | 20641564 | 20641587 | 14 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GTCTATCTCCTGAATCTGACAGG | OR6S1 | ENSG00000181803 | -2.89157499216821 | [] | [] | -3 | hSpCas9 | negative selection | 3540200 | 20641535 | 20641558 | 14 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GTTGATTGTGGGGGTGGTAAGGG | OR6S1 | ENSG00000181803 | 3.10652382012738 | [] | [] | 5 | hSpCas9 | negative selection | 3540201 | 20641267 | 20641290 | 14 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ACAGCCCCACTCATGAGCAAGGG | OR6S1 | ENSG00000181803 | 0.464114231624755 | [] | [] | 0 | hSpCas9 | negative selection | 3540202 | 20641652 | 20641675 | 14 | + | 26780180 | A375 | viability (Avana lentiGuide) | ACTCTGTTGGATCACTACTGTGG | OR6S1 | ENSG00000181803 | -2.83256321428885 | [] | [] | -5 | hSpCas9 | negative selection | 3648858 | 20641564 | 20641587 | 14 | - | 26780180 | A375 | viability (Avana lentiGuide) | GTCTATCTCCTGAATCTGACAGG | OR6S1 | ENSG00000181803 | -4.98982993190643 | [] | [] | -8 | hSpCas9 | negative selection | 3648859 | 20641535 | 20641558 | 14 | - | 26780180 | A375 | viability (Avana lentiGuide) | GTTGATTGTGGGGGTGGTAAGGG | OR6S1 | ENSG00000181803 | 0.996644465174835 | [] | [] | 1 | hSpCas9 | negative selection | 3648860 | 20641267 | 20641290 | 14 | + | 26780180 | A375 | viability (Avana lentiGuide) | ACAGCCCCACTCATGAGCAAGGG | OR6S1 | ENSG00000181803 | -2.66423907293516 | [] | [] | -5 | hSpCas9 | negative selection | 3648861 | 20641652 | 20641675 | 14 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ACTCTGTTGGATCACTACTGTGG | OR6S1 | ENSG00000181803 | 0.07097976357416527 | [6] | [6,6] | 1 | hSpCas9 | positive selection | 3757517 | 20641564 | 20641587 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GTCTATCTCCTGAATCTGACAGG | OR6S1 | ENSG00000181803 | -0.164520922918388 | [5] | [4,4] | -3 | hSpCas9 | positive selection | 3757518 | 20641535 | 20641558 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GTTGATTGTGGGGGTGGTAAGGG | OR6S1 | ENSG00000181803 | -0.16273224694327215 | [3] | [3,3] | -3 | hSpCas9 | positive selection | 3757519 | 20641267 | 20641290 | 14 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ACAGCCCCACTCATGAGCAAGGG | OR6S1 | ENSG00000181803 | -0.24283903372633725 | [4] | [3,3] | -4 | hSpCas9 | positive selection | 3757520 | 20641652 | 20641675 | 14 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ACTCTGTTGGATCACTACTGTGG | OR6S1 | ENSG00000181803 | 0.22396509988987245 | [5] | [5,5] | 6 | hSpCas9 | positive selection | 3866124 | 20641564 | 20641587 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GTCTATCTCCTGAATCTGACAGG | OR6S1 | ENSG00000181803 | 0.16397047224608838 | [6] | [6,4] | 4 | hSpCas9 | positive selection | 3866125 | 20641535 | 20641558 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GTTGATTGTGGGGGTGGTAAGGG | OR6S1 | ENSG00000181803 | -0.11048765203547656 | [4] | [3,2] | -1 | hSpCas9 | positive selection | 3866126 | 20641267 | 20641290 | 14 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ACAGCCCCACTCATGAGCAAGGG | OR6S1 | ENSG00000181803 | 0.4710366871392556 | [4] | [4,6] | 9 | hSpCas9 | positive selection | 3866127 | 20641313 | 20641336 | 14 | - | 26780180 | A375 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.748061372421362 | [] | [] | 2 | hSpCas9 | negative selection | 3977019 | 20641639 | 20641662 | 14 | + | 26780180 | A375 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | 1.13552188386049 | [] | [] | 6 | hSpCas9 | negative selection | 3977020 | 20641273 | 20641296 | 14 | - | 26780180 | A375 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 1.08505214906774 | [] | [] | 5 | hSpCas9 | negative selection | 3977021 | 20640789 | 20640812 | 14 | + | 26780180 | A375 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.960942835843965 | [] | [] | 4 | hSpCas9 | negative selection | 3977022 | 20641340 | 20641363 | 14 | - | 26780180 | A375 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | 1.48531750231529 | [] | [] | 8 | hSpCas9 | negative selection | 3977023 | 20641643 | 20641666 | 14 | - | 26780180 | A375 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 1.94820412363135 | [] | [] | 9 | hSpCas9 | negative selection | 3977024 | 20641313 | 20641336 | 14 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.776935554412998 | [] | [] | 3 | hSpCas9 | negative selection | 4084985 | 20641639 | 20641662 | 14 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | 2.00660935205771 | [] | [] | 9 | hSpCas9 | negative selection | 4084986 | 20641273 | 20641296 | 14 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.351367815648261 | [] | [] | 1 | hSpCas9 | negative selection | 4084987 | 20640789 | 20640812 | 14 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.62272504907572 | [] | [] | 2 | hSpCas9 | negative selection | 4084988 | 20641340 | 20641363 | 14 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | 1.6599507226069 | [] | [] | 8 | hSpCas9 | negative selection | 4084989 | 20641643 | 20641666 | 14 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 3.14632222878796 | [] | [] | 9 | hSpCas9 | negative selection | 4084990 | 20641612 | 20641635 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | ACTCTTGCGCTGTTGAGATTTGG | OR6S1 | ENSG00000181803 | -0.1644288980892192 | [4] | [2,1] | -4 | hSpCas9 | positive selection | 4157984 | 20641313 | 20641336 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.005373694078694535 | [4] | [2,2] | 0 | hSpCas9 | positive selection | 4157985 | 20641612 | 20641635 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | ACTCTTGCGCTGTTGAGATTTGG | OR6S1 | ENSG00000181803 | -0.15556402068591135 | [3] | [1,2,1,0] | -2 | hSpCas9 | positive selection | 4222006 | 20641313 | 20641336 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.20255327980469265 | [3] | [3,3,1,0] | 1 | hSpCas9 | positive selection | 4222007 | 20640789 | 20640812 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.20026682939387722 | [3] | [3,2] | 4 | hSpCas9 | positive selection | 4288091 | 20641313 | 20641336 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.45172778389358903 | [3] | [4,3] | 8 | hSpCas9 | positive selection | 4288092 | 20641643 | 20641666 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | -0.6101624698812362 | [3] | [2,0] | -8 | hSpCas9 | positive selection | 4288093 | 20641639 | 20641662 | 14 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.15864356843216482 | [3] | [3,0] | -3 | hSpCas9 | positive selection | 4352347 | 20641340 | 20641363 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.31208248833883573 | [3] | [2,0] | -6 | hSpCas9 | positive selection | 4352348 | 20641273 | 20641296 | 14 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.34368012603187104 | [3] | [4,2] | 7 | hSpCas9 | positive selection | 4352349 | 20641340 | 20641363 | 14 | - | 27661255 | K562 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | 0.08750060447365726 | [360,480] | [402,314] | 3 | dCas9-KRAB | negative selection | 5499374 | 20640789 | 20640812 | 14 | + | 27260156 | BXPC3 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.1565454507187115 | [568] | [427,645,823,795] | 3 | hSpCas9 | negative selection | 5560551 | 20641313 | 20641336 | 14 | - | 27260156 | BXPC3 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.215272974406848 | [718] | [539,553,765,758] | -5 | hSpCas9 | negative selection | 5560552 | 20641643 | 20641666 | 14 | - | 27260156 | BXPC3 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.21447087494363615 | [669] | [850,690,853,858] | 5 | hSpCas9 | negative selection | 5560553 | 20641639 | 20641662 | 14 | + | 27260156 | BXPC3 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.2804514186897093 | [479] | [345,454,335,530] | -6 | hSpCas9 | negative selection | 5624807 | 20641340 | 20641363 | 14 | - | 27260156 | BXPC3 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.46886680525419666 | [521] | [359,335,349,554] | -7 | hSpCas9 | negative selection | 5624808 | 20641273 | 20641296 | 14 | - | 27260156 | BXPC3 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.1794693933318639 | [556] | [435,583,876,784] | 4 | hSpCas9 | negative selection | 5624809 | 20640789 | 20640812 | 14 | + | 27260156 | A673 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.16229913467173318 | [568] | [817,642,757,851] | 4 | hSpCas9 | negative selection | 5681802 | 20641313 | 20641336 | 14 | - | 27260156 | A673 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.12568887581642024 | [718] | [825,762,807,769] | -3 | hSpCas9 | negative selection | 5681803 | 20641643 | 20641666 | 14 | - | 27260156 | A673 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.20603256614729226 | [669] | [978,763,1006,971] | 5 | hSpCas9 | negative selection | 5681804 | 20641639 | 20641662 | 14 | + | 27260156 | A673 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.21040658102671747 | [479] | [462,428,457,647] | -5 | hSpCas9 | negative selection | 5746058 | 20641340 | 20641363 | 14 | - | 27260156 | A673 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.3648732261476699 | [521] | [492,499,487,463] | -7 | hSpCas9 | negative selection | 5746059 | 20641273 | 20641296 | 14 | - | 27260156 | A673 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.04201161143867349 | [556] | [624,625,676,826] | 1 | hSpCas9 | negative selection | 5746060 | 20640789 | 20640812 | 14 | + | 27260156 | A375 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.31400354030848154 | [568] | [940,1011,879,530] | 4 | hSpCas9 | negative selection | 5803053 | 20641313 | 20641336 | 14 | - | 27260156 | A375 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.3277208449294431 | [718] | [1071,1386,937,881] | 5 | hSpCas9 | negative selection | 5803054 | 20641643 | 20641666 | 14 | - | 27260156 | A375 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.40531421201378803 | [669] | [948,1463,987,824] | 6 | hSpCas9 | negative selection | 5803055 | 20641639 | 20641662 | 14 | + | 27260156 | A375 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | 0.05531495102021912 | [479] | [461,790,584,524] | 0 | hSpCas9 | negative selection | 5867309 | 20641340 | 20641363 | 14 | - | 27260156 | A375 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | 0.06359250435411928 | [521] | [524,673,829,533] | 0 | hSpCas9 | negative selection | 5867310 | 20641273 | 20641296 | 14 | - | 27260156 | A375 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.22124605086460614 | [556] | [667,750,805,798] | 3 | hSpCas9 | negative selection | 5867311 | 20640789 | 20640812 | 14 | + | 27260156 | COLO741 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.3250381151685583 | [568] | [1036,923,788] | 6 | hSpCas9 | negative selection | 5924304 | 20641313 | 20641336 | 14 | - | 27260156 | COLO741 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.05118735585664991 | [718] | [1222,953,716] | 1 | hSpCas9 | negative selection | 5924305 | 20641643 | 20641666 | 14 | - | 27260156 | COLO741 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.16230341574204965 | [669] | [921,948,994] | 3 | hSpCas9 | negative selection | 5924306 | 20641639 | 20641662 | 14 | + | 27260156 | COLO741 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.261041720762905 | [479] | [671,593,297] | -5 | hSpCas9 | negative selection | 5988560 | 20641340 | 20641363 | 14 | - | 27260156 | COLO741 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.2559243702185536 | [521] | [612,675,401] | -5 | hSpCas9 | negative selection | 5988561 | 20641273 | 20641296 | 14 | - | 27260156 | COLO741 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.09543737039177519 | [556] | [834,849,611] | 2 | hSpCas9 | negative selection | 5988562 | 20640789 | 20640812 | 14 | + | 27260156 | CAL120 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.07334744809484253 | [568] | [748,661,619] | -1 | hSpCas9 | negative selection | 6045555 | 20641313 | 20641336 | 14 | - | 27260156 | CAL120 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.10038499421204794 | [718] | [1137,914,852] | 1 | hSpCas9 | negative selection | 6045556 | 20641643 | 20641666 | 14 | - | 27260156 | CAL120 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.3128819618690384 | [669] | [978,1081,1036] | 5 | hSpCas9 | negative selection | 6045557 | 20641639 | 20641662 | 14 | + | 27260156 | CAL120 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | 0.2769374609329582 | [479] | [935,723,545] | 4 | hSpCas9 | negative selection | 6109811 | 20641340 | 20641363 | 14 | - | 27260156 | CAL120 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.49653937725808883 | [521] | [421,476,475] | -6 | hSpCas9 | negative selection | 6109812 | 20641273 | 20641296 | 14 | - | 27260156 | CAL120 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.3212219017471106 | [556] | [1097,696,837] | 5 | hSpCas9 | negative selection | 6109813 | 20640789 | 20640812 | 14 | + | 27260156 | CADOES1 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.3167844614080281 | [568] | [964,555,573,535] | 5 | hSpCas9 | negative selection | 6166806 | 20641313 | 20641336 | 14 | - | 27260156 | CADOES1 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.06469398555809835 | [718] | [671,936,645,536] | 1 | hSpCas9 | negative selection | 6166807 | 20641643 | 20641666 | 14 | - | 27260156 | CADOES1 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.3515948580446363 | [669] | [703,737,777,966] | 6 | hSpCas9 | negative selection | 6166808 | 20641639 | 20641662 | 14 | + | 27260156 | CADOES1 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.16562417765497658 | [479] | [355,379,434,421] | -3 | hSpCas9 | negative selection | 6231062 | 20641340 | 20641363 | 14 | - | 27260156 | CADOES1 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.3942130591816043 | [521] | [378,299,338,462] | -6 | hSpCas9 | negative selection | 6231063 | 20641273 | 20641296 | 14 | - | 27260156 | CADOES1 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.2254347975800518 | [556] | [611,633,562,613] | 4 | hSpCas9 | negative selection | 6231064 | 20640789 | 20640812 | 14 | + | 27260156 | EWS502 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.23204515361050337 | [568] | [406,609,784,1095] | 4 | hSpCas9 | negative selection | 6288057 | 20641313 | 20641336 | 14 | - | 27260156 | EWS502 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.013535685462145564 | [718] | [642,802,843,798] | 0 | hSpCas9 | negative selection | 6288058 | 20641643 | 20641666 | 14 | - | 27260156 | EWS502 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.08404538434625608 | [669] | [688,781,643,906] | 1 | hSpCas9 | negative selection | 6288059 | 20641639 | 20641662 | 14 | + | 27260156 | EWS502 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.30890301049004637 | [479] | [433,333,414,460] | -5 | hSpCas9 | negative selection | 6352313 | 20641340 | 20641363 | 14 | - | 27260156 | EWS502 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.20822960489834297 | [521] | [461,511,441,497] | -4 | hSpCas9 | negative selection | 6352314 | 20641273 | 20641296 | 14 | - | 27260156 | EWS502 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.3403961490635502 | [556] | [353,574,513,425] | -5 | hSpCas9 | negative selection | 6352315 | 20640789 | 20640812 | 14 | + | 27260156 | EW8 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.0990652953290814 | [568] | [559,402,449,318] | -2 | hSpCas9 | negative selection | 6409308 | 20641313 | 20641336 | 14 | - | 27260156 | EW8 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.047654389288316557 | [718] | [686,509,400,695] | -1 | hSpCas9 | negative selection | 6409309 | 20641643 | 20641666 | 14 | - | 27260156 | EW8 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.32299273323228195 | [669] | [847,678,654,555] | 6 | hSpCas9 | negative selection | 6409310 | 20641639 | 20641662 | 14 | + | 27260156 | EW8 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.18745840851546183 | [479] | [475,210,350,339] | -4 | hSpCas9 | negative selection | 6473564 | 20641340 | 20641363 | 14 | - | 27260156 | EW8 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.3070994674853283 | [521] | [465,466,189,283] | -5 | hSpCas9 | negative selection | 6473565 | 20641273 | 20641296 | 14 | - | 27260156 | EW8 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.00958533963298347 | [556] | [653,335,399,456] | 0 | hSpCas9 | negative selection | 6473566 | 20640789 | 20640812 | 14 | + | 27260156 | CORL105 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.24838879271817066 | [568] | [542,671,532,487] | -4 | hSpCas9 | negative selection | 6530559 | 20641313 | 20641336 | 14 | - | 27260156 | CORL105 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.14692175910385286 | [718] | [818,715,862,661] | -3 | hSpCas9 | negative selection | 6530560 | 20641643 | 20641666 | 14 | - | 27260156 | CORL105 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.3673299057569732 | [669] | [961,1003,1117,977] | 6 | hSpCas9 | negative selection | 6530561 | 20641639 | 20641662 | 14 | + | 27260156 | CORL105 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.33098432594273935 | [479] | [358,349,634,470] | -6 | hSpCas9 | negative selection | 6594815 | 20641340 | 20641363 | 14 | - | 27260156 | CORL105 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.44704131479764997 | [521] | [425,427,595,365] | -7 | hSpCas9 | negative selection | 6594816 | 20641273 | 20641296 | 14 | - | 27260156 | CORL105 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.08834545929916451 | [556] | [611,619,650,575] | -2 | hSpCas9 | negative selection | 6594817 | 20640789 | 20640812 | 14 | + | 27260156 | HS294T | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.3576530664724682 | [568] | [359,205,206,361] | 5 | hSpCas9 | negative selection | 6651810 | 20641313 | 20641336 | 14 | - | 27260156 | HS294T | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.09225288099157924 | [718] | [196,370,249,388] | 1 | hSpCas9 | negative selection | 6651811 | 20641643 | 20641666 | 14 | - | 27260156 | HS294T | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.4163323064335067 | [669] | [259,353,393,388] | 5 | hSpCas9 | negative selection | 6651812 | 20641639 | 20641662 | 14 | + | 27260156 | HS294T | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.2650100797298994 | [479] | [107,136,209,169] | -4 | hSpCas9 | negative selection | 6716066 | 20641340 | 20641363 | 14 | - | 27260156 | HS294T | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | 0.2945311246913088 | [521] | [235,214,240,309] | 4 | hSpCas9 | negative selection | 6716067 | 20641273 | 20641296 | 14 | - | 27260156 | HS294T | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.13519492070621159 | [556] | [245,157,195,176] | -2 | hSpCas9 | negative selection | 6716068 | 20640789 | 20640812 | 14 | + | 27260156 | HCC44 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.4326210610731237 | [568] | [537,457,507,414] | -6 | hSpCas9 | negative selection | 6773061 | 20641313 | 20641336 | 14 | - | 27260156 | HCC44 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.12609729803134928 | [718] | [799,899,787,1022] | 2 | hSpCas9 | negative selection | 6773062 | 20641643 | 20641666 | 14 | - | 27260156 | HCC44 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | -0.021410192017688123 | [669] | [644,645,852,855] | 0 | hSpCas9 | negative selection | 6773063 | 20641639 | 20641662 | 14 | + | 27260156 | HCC44 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.5973371609227232 | [479] | [444,393,297,289] | -7 | hSpCas9 | negative selection | 6837317 | 20641340 | 20641363 | 14 | - | 27260156 | HCC44 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.4552158279438942 | [521] | [366,485,387,455] | -6 | hSpCas9 | negative selection | 6837318 | 20641273 | 20641296 | 14 | - | 27260156 | HCC44 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.25838914045704603 | [556] | [751,373,632,407] | -4 | hSpCas9 | negative selection | 6837319 | 20640789 | 20640812 | 14 | + | 27260156 | G402 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.20275587561188807 | [568] | [408,1224,864,668] | 2 | hSpCas9 | negative selection | 6894312 | 20641313 | 20641336 | 14 | - | 27260156 | G402 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.039317022044257355 | [718] | [871,701,840,983] | 0 | hSpCas9 | negative selection | 6894313 | 20641643 | 20641666 | 14 | - | 27260156 | G402 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.8151969113297804 | [669] | [1084,1990,1502,1163] | 8 | hSpCas9 | negative selection | 6894314 | 20641639 | 20641662 | 14 | + | 27260156 | G402 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.19282215539644615 | [479] | [520,656,380,498] | -2 | hSpCas9 | negative selection | 6958568 | 20641340 | 20641363 | 14 | - | 27260156 | G402 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.30710359604629967 | [521] | [560,567,697,252] | -4 | hSpCas9 | negative selection | 6958569 | 20641273 | 20641296 | 14 | - | 27260156 | G402 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.0696680910529163 | [556] | [388,825,762,585] | -1 | hSpCas9 | negative selection | 6958570 | 20640789 | 20640812 | 14 | + | 27260156 | L33 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.16233690985724003 | [568] | [409,262,297,509] | -4 | hSpCas9 | negative selection | 7015563 | 20641313 | 20641336 | 14 | - | 27260156 | L33 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.0913771705724622 | [718] | [658,294,515,865] | 2 | hSpCas9 | negative selection | 7015564 | 20641643 | 20641666 | 14 | - | 27260156 | L33 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.09999687702794124 | [669] | [725,341,443,605] | 2 | hSpCas9 | negative selection | 7015565 | 20641639 | 20641662 | 14 | + | 27260156 | L33 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.05902591079825242 | [479] | [540,181,275,416] | -1 | hSpCas9 | negative selection | 7079819 | 20641340 | 20641363 | 14 | - | 27260156 | L33 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | 0.00946596069716743 | [521] | [568,187,293,603] | 0 | hSpCas9 | negative selection | 7079820 | 20641273 | 20641296 | 14 | - | 27260156 | L33 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.13551734694003015 | [556] | [562,222,346,368] | -3 | hSpCas9 | negative selection | 7079821 | 20640789 | 20640812 | 14 | + | 27260156 | K562 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.09156588898770157 | [568] | [499,388,627,612] | 1 | hSpCas9 | negative selection | 7136814 | 20641313 | 20641336 | 14 | - | 27260156 | K562 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.37430367117572605 | [718] | [996,1254,628,498] | 5 | hSpCas9 | negative selection | 7136815 | 20641643 | 20641666 | 14 | - | 27260156 | K562 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.2633964516237376 | [669] | [646,966,366,860] | 3 | hSpCas9 | negative selection | 7136816 | 20641639 | 20641662 | 14 | + | 27260156 | K562 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.39307165328769317 | [479] | [299,442,257,301] | -5 | hSpCas9 | negative selection | 7201070 | 20641340 | 20641363 | 14 | - | 27260156 | K562 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -1.0232953445820168 | [521] | [230,314,136,231] | -8 | hSpCas9 | negative selection | 7201071 | 20641273 | 20641296 | 14 | - | 27260156 | K562 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.2505639609565199 | [556] | [538,361,336,427] | -3 | hSpCas9 | negative selection | 7201072 | 20640789 | 20640812 | 14 | + | 27260156 | HT29 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.17480164500246986 | [568] | [839,697,904,683] | 3 | hSpCas9 | negative selection | 7258065 | 20641313 | 20641336 | 14 | - | 27260156 | HT29 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.008665229332890156 | [718] | [995,903,823,769] | 0 | hSpCas9 | negative selection | 7258066 | 20641643 | 20641666 | 14 | - | 27260156 | HT29 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.3081891639926412 | [669] | [1065,1078,920,974] | 6 | hSpCas9 | negative selection | 7258067 | 20641639 | 20641662 | 14 | + | 27260156 | HT29 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.3658264212771781 | [479] | [487,564,401,374] | -6 | hSpCas9 | negative selection | 7322321 | 20641340 | 20641363 | 14 | - | 27260156 | HT29 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.09313157909705752 | [521] | [566,467,703,619] | -2 | hSpCas9 | negative selection | 7322322 | 20641273 | 20641296 | 14 | - | 27260156 | HT29 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.1686369994386594 | [556] | [898,724,587,825] | 3 | hSpCas9 | negative selection | 7322323 | 20640789 | 20640812 | 14 | + | 27260156 | MHHES1 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.058101240173921154 | [568] | [742,733,659,557] | 1 | hSpCas9 | negative selection | 7379316 | 20641313 | 20641336 | 14 | - | 27260156 | MHHES1 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.005283014852576318 | [718] | [791,833,820,770] | 0 | hSpCas9 | negative selection | 7379317 | 20641643 | 20641666 | 14 | - | 27260156 | MHHES1 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.12078286774958402 | [669] | [900,947,765,698] | 2 | hSpCas9 | negative selection | 7379318 | 20641639 | 20641662 | 14 | + | 27260156 | MHHES1 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | 0.2392285182353474 | [479] | [761,768,631,447] | 4 | hSpCas9 | negative selection | 7443572 | 20641340 | 20641363 | 14 | - | 27260156 | MHHES1 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | 0.08311737984842507 | [521] | [838,630,681,403] | 1 | hSpCas9 | negative selection | 7443573 | 20641273 | 20641296 | 14 | - | 27260156 | MHHES1 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.15718128662708092 | [556] | [539,662,447,586] | -3 | hSpCas9 | negative selection | 7443574 | 20640789 | 20640812 | 14 | + | 27260156 | MEWO | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.25224038006988303 | [568] | [785,514,630] | 5 | hSpCas9 | negative selection | 7500567 | 20641313 | 20641336 | 14 | - | 27260156 | MEWO | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.043114245793239414 | [718] | [676,677,607] | -1 | hSpCas9 | negative selection | 7500568 | 20641643 | 20641666 | 14 | - | 27260156 | MEWO | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.2596015902236699 | [669] | [959,678,652] | 5 | hSpCas9 | negative selection | 7500569 | 20641639 | 20641662 | 14 | + | 27260156 | MEWO | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.12463823477440227 | [479] | [484,365,398] | -3 | hSpCas9 | negative selection | 7564823 | 20641340 | 20641363 | 14 | - | 27260156 | MEWO | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | 0.10748305974387934 | [521] | [637,518,442] | 2 | hSpCas9 | negative selection | 7564824 | 20641273 | 20641296 | 14 | - | 27260156 | MEWO | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.009479503197108996 | [556] | [537,497,520] | 0 | hSpCas9 | negative selection | 7564825 | 20640789 | 20640812 | 14 | + | 27260156 | LNCAPCLONEFGC | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.12849296939963314 | [568] | [377,504,529,480] | -2 | hSpCas9 | negative selection | 7621818 | 20641313 | 20641336 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.2302542312649858 | [718] | [657,731,893,794] | 3 | hSpCas9 | negative selection | 7621819 | 20641643 | 20641666 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.30757369905662035 | [669] | [763,736,671,819] | 5 | hSpCas9 | negative selection | 7621820 | 20641639 | 20641662 | 14 | + | 27260156 | LNCAPCLONEFGC | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.030236079143264576 | [479] | [373,472,514,351] | 0 | hSpCas9 | negative selection | 7686074 | 20641340 | 20641363 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.35280605233887685 | [521] | [367,374,453,295] | -5 | hSpCas9 | negative selection | 7686075 | 20641273 | 20641296 | 14 | - | 27260156 | LNCAPCLONEFGC | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.13082543446933845 | [556] | [417,432,624,393] | -2 | hSpCas9 | negative selection | 7686076 | 20640789 | 20640812 | 14 | + | 27260156 | PANC0327 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.04579508204303384 | [568] | [509,507,574,364] | 0 | hSpCas9 | negative selection | 7743069 | 20641313 | 20641336 | 14 | - | 27260156 | PANC0327 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.023995829082640086 | [718] | [792,736,629,437] | 0 | hSpCas9 | negative selection | 7743070 | 20641643 | 20641666 | 14 | - | 27260156 | PANC0327 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.12865085311792146 | [669] | [584,643,672,695] | 1 | hSpCas9 | negative selection | 7743071 | 20641639 | 20641662 | 14 | + | 27260156 | PANC0327 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.15983872461892384 | [479] | [292,328,380,522] | -2 | hSpCas9 | negative selection | 7807325 | 20641340 | 20641363 | 14 | - | 27260156 | PANC0327 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.34926473653828743 | [521] | [270,344,522,311] | -5 | hSpCas9 | negative selection | 7807326 | 20641273 | 20641296 | 14 | - | 27260156 | PANC0327 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.15872114427024708 | [556] | [524,339,514,412] | -2 | hSpCas9 | negative selection | 7807327 | 20640789 | 20640812 | 14 | + | 27260156 | NCIH2009 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.004661566425725461 | [568] | [935,642,827] | 0 | hSpCas9 | negative selection | 7864320 | 20641313 | 20641336 | 14 | - | 27260156 | NCIH2009 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.01718169258422575 | [718] | [1324,826,892] | 0 | hSpCas9 | negative selection | 7864321 | 20641643 | 20641666 | 14 | - | 27260156 | NCIH2009 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.33755530724411886 | [669] | [1313,989,1271] | 4 | hSpCas9 | negative selection | 7864322 | 20641639 | 20641662 | 14 | + | 27260156 | NCIH2009 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | 0.11739044690955894 | [479] | [861,716,628] | 1 | hSpCas9 | negative selection | 7928576 | 20641340 | 20641363 | 14 | - | 27260156 | NCIH2009 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.06876068787174722 | [521] | [743,504,848] | -1 | hSpCas9 | negative selection | 7928577 | 20641273 | 20641296 | 14 | - | 27260156 | NCIH2009 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.1976913964051497 | [556] | [1460,912,413] | 2 | hSpCas9 | negative selection | 7928578 | 20640789 | 20640812 | 14 | + | 27260156 | NCIH1373 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.7199640914361931 | [568] | [719,328,280,70] | -6 | hSpCas9 | negative selection | 7985571 | 20641313 | 20641336 | 14 | - | 27260156 | NCIH1373 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.13017057503896146 | [718] | [1195,725,859,210] | 1 | hSpCas9 | negative selection | 7985572 | 20641643 | 20641666 | 14 | - | 27260156 | NCIH1373 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.21718294354496626 | [669] | [1239,750,782,204] | 2 | hSpCas9 | negative selection | 7985573 | 20641639 | 20641662 | 14 | + | 27260156 | NCIH1373 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.026659381683772528 | [479] | [718,569,310,141] | 0 | hSpCas9 | negative selection | 8049827 | 20641340 | 20641363 | 14 | - | 27260156 | NCIH1373 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.674295393588368 | [521] | [327,313,461,93] | -6 | hSpCas9 | negative selection | 8049828 | 20641273 | 20641296 | 14 | - | 27260156 | NCIH1373 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.20333280150813182 | [556] | [791,483,432,131] | -2 | hSpCas9 | negative selection | 8049829 | 20640789 | 20640812 | 14 | + | 27260156 | PATU8902 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.0931718573784143 | [568] | [595,641,877,825] | -1 | hSpCas9 | negative selection | 8106822 | 20641313 | 20641336 | 14 | - | 27260156 | PATU8902 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.23066354116060195 | [718] | [1351,1183,685,1649] | 2 | hSpCas9 | negative selection | 8106823 | 20641643 | 20641666 | 14 | - | 27260156 | PATU8902 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.6725746106217186 | [669] | [1691,1668,1061,1640] | 7 | hSpCas9 | negative selection | 8106824 | 20641639 | 20641662 | 14 | + | 27260156 | PATU8902 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.18030218786847366 | [479] | [653,540,513,674] | -2 | hSpCas9 | negative selection | 8171078 | 20641340 | 20641363 | 14 | - | 27260156 | PATU8902 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.891862782554319 | [521] | [614,297,352,292] | -7 | hSpCas9 | negative selection | 8171079 | 20641273 | 20641296 | 14 | - | 27260156 | PATU8902 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.31190860225533334 | [556] | [1214,880,1147,491] | 3 | hSpCas9 | negative selection | 8171080 | 20640789 | 20640812 | 14 | + | 27260156 | PANC1 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.1311506928397112 | [568] | [492,542,512,577] | 2 | hSpCas9 | negative selection | 8228073 | 20641313 | 20641336 | 14 | - | 27260156 | PANC1 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.0628394758592381 | [718] | [669,618,662,433] | -1 | hSpCas9 | negative selection | 8228074 | 20641643 | 20641666 | 14 | - | 27260156 | PANC1 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.011708441857945173 | [669] | [475,671,648,541] | 0 | hSpCas9 | negative selection | 8228075 | 20641639 | 20641662 | 14 | + | 27260156 | PANC1 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.05157407422294273 | [479] | [405,423,411,354] | -1 | hSpCas9 | negative selection | 8292329 | 20641340 | 20641363 | 14 | - | 27260156 | PANC1 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.25953805978730415 | [521] | [320,283,380,471] | -4 | hSpCas9 | negative selection | 8292330 | 20641273 | 20641296 | 14 | - | 27260156 | PANC1 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.08686986947830999 | [556] | [443,621,603,397] | 1 | hSpCas9 | negative selection | 8292331 | 20640789 | 20640812 | 14 | + | 27260156 | PANC0813 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.6170356622365953 | [568] | [492,570,354,333] | -7 | hSpCas9 | negative selection | 8349324 | 20641313 | 20641336 | 14 | - | 27260156 | PANC0813 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.02711181370654281 | [718] | [1102,715,660,856] | 0 | hSpCas9 | negative selection | 8349325 | 20641643 | 20641666 | 14 | - | 27260156 | PANC0813 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.11188414927317647 | [669] | [757,863,863,902] | 1 | hSpCas9 | negative selection | 8349326 | 20641639 | 20641662 | 14 | + | 27260156 | PANC0813 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.5547512594733968 | [479] | [648,325,295,292] | -7 | hSpCas9 | negative selection | 8413580 | 20641340 | 20641363 | 14 | - | 27260156 | PANC0813 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.9743059675175629 | [521] | [352,193,339,361] | -8 | hSpCas9 | negative selection | 8413581 | 20641273 | 20641296 | 14 | - | 27260156 | PANC0813 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.7269918255068339 | [556] | [444,427,458,260] | -8 | hSpCas9 | negative selection | 8413582 | 20640789 | 20640812 | 14 | + | 27260156 | RDES | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.13689437871164314 | [568] | [457,531,620,823] | -2 | hSpCas9 | negative selection | 8470575 | 20641313 | 20641336 | 14 | - | 27260156 | RDES | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.0793393635205607 | [718] | [698,704,755,1003] | -1 | hSpCas9 | negative selection | 8470576 | 20641643 | 20641666 | 14 | - | 27260156 | RDES | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.3271907149591041 | [669] | [752,929,1066,1172] | 5 | hSpCas9 | negative selection | 8470577 | 20641639 | 20641662 | 14 | + | 27260156 | RDES | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.293692747519862 | [479] | [371,371,550,533] | -5 | hSpCas9 | negative selection | 8534831 | 20641340 | 20641363 | 14 | - | 27260156 | RDES | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.7866281681354422 | [521] | [249,270,452,457] | -8 | hSpCas9 | negative selection | 8534832 | 20641273 | 20641296 | 14 | - | 27260156 | RDES | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.11689278366898914 | [556] | [587,681,781,738] | 2 | hSpCas9 | negative selection | 8534833 | 20640789 | 20640812 | 14 | + | 27260156 | PC3 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.1993093063682132 | [568] | [460,644,966,667] | 4 | hSpCas9 | negative selection | 8591826 | 20641313 | 20641336 | 14 | - | 27260156 | PC3 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.1745206282415923 | [718] | [439,527,1204,612] | -4 | hSpCas9 | negative selection | 8591827 | 20641643 | 20641666 | 14 | - | 27260156 | PC3 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.037486256248776106 | [669] | [408,676,1138,753] | 0 | hSpCas9 | negative selection | 8591828 | 20641639 | 20641662 | 14 | + | 27260156 | PC3 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.2512840329766593 | [479] | [259,278,663,542] | -5 | hSpCas9 | negative selection | 8656082 | 20641340 | 20641363 | 14 | - | 27260156 | PC3 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | 0.07687888518664607 | [521] | [271,509,1208,541] | 1 | hSpCas9 | negative selection | 8656083 | 20641273 | 20641296 | 14 | - | 27260156 | PC3 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.135905289343 | [556] | [380,561,1219,556] | 3 | hSpCas9 | negative selection | 8656084 | 20640789 | 20640812 | 14 | + | 27260156 | PATU8988T | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.1907316890354258 | [568] | [539,628,555,799] | 3 | hSpCas9 | negative selection | 8713077 | 20641313 | 20641336 | 14 | - | 27260156 | PATU8988T | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.2481155899087678 | [718] | [661,1104,880,664] | 4 | hSpCas9 | negative selection | 8713078 | 20641643 | 20641666 | 14 | - | 27260156 | PATU8988T | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | -0.07866231842072091 | [669] | [637,476,739,579] | -1 | hSpCas9 | negative selection | 8713079 | 20641639 | 20641662 | 14 | + | 27260156 | PATU8988T | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.24150276460040604 | [479] | [406,374,457,320] | -4 | hSpCas9 | negative selection | 8777333 | 20641340 | 20641363 | 14 | - | 27260156 | PATU8988T | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.22336420738338766 | [521] | [400,279,496,543] | -4 | hSpCas9 | negative selection | 8777334 | 20641273 | 20641296 | 14 | - | 27260156 | PATU8988T | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.31968115775680617 | [556] | [417,487,361,465] | -5 | hSpCas9 | negative selection | 8777335 | 20640789 | 20640812 | 14 | + | 27260156 | T47D | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.22372291925348253 | [568] | [749,690,751,914] | 5 | hSpCas9 | negative selection | 8834328 | 20641313 | 20641336 | 14 | - | 27260156 | T47D | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | 0.022672115696980022 | [718] | [894,732,779,1011] | 0 | hSpCas9 | negative selection | 8834329 | 20641643 | 20641666 | 14 | - | 27260156 | T47D | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.1795658476810862 | [669] | [804,756,1016,967] | 4 | hSpCas9 | negative selection | 8834330 | 20641639 | 20641662 | 14 | + | 27260156 | T47D | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.16074464876872702 | [479] | [479,502,560,453] | -4 | hSpCas9 | negative selection | 8898584 | 20641340 | 20641363 | 14 | - | 27260156 | T47D | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.0626698189513392 | [521] | [583,680,453,603] | -1 | hSpCas9 | negative selection | 8898585 | 20641273 | 20641296 | 14 | - | 27260156 | T47D | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.14539925743073107 | [556] | [804,626,640,809] | 3 | hSpCas9 | negative selection | 8898586 | 20640789 | 20640812 | 14 | + | 27260156 | SU8686 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.12441996993768153 | [568] | [606,353,442,700] | -2 | hSpCas9 | negative selection | 8955579 | 20641313 | 20641336 | 14 | - | 27260156 | SU8686 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.04690499949999827 | [718] | [571,619,686,938] | -1 | hSpCas9 | negative selection | 8955580 | 20641643 | 20641666 | 14 | - | 27260156 | SU8686 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.13273079402679178 | [669] | [597,774,729,829] | 2 | hSpCas9 | negative selection | 8955581 | 20641639 | 20641662 | 14 | + | 27260156 | SU8686 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.2947148918390604 | [479] | [331,387,386,459] | -5 | hSpCas9 | negative selection | 9019835 | 20641340 | 20641363 | 14 | - | 27260156 | SU8686 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.17067138350631225 | [521] | [344,444,379,720] | -3 | hSpCas9 | negative selection | 9019836 | 20641273 | 20641296 | 14 | - | 27260156 | SU8686 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.24265315615431973 | [556] | [377,384,520,627] | -4 | hSpCas9 | negative selection | 9019837 | 20640789 | 20640812 | 14 | + | 27260156 | SKES1 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.19475166467386879 | [568] | [543,691,753,596] | 4 | hSpCas9 | negative selection | 9076830 | 20641313 | 20641336 | 14 | - | 27260156 | SKES1 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.043037062242038515 | [718] | [797,851,683,499] | -1 | hSpCas9 | negative selection | 9076831 | 20641643 | 20641666 | 14 | - | 27260156 | SKES1 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.24650966923242523 | [669] | [975,768,716,731] | 5 | hSpCas9 | negative selection | 9076832 | 20641639 | 20641662 | 14 | + | 27260156 | SKES1 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.4108339305757673 | [479] | [393,415,379,268] | -7 | hSpCas9 | negative selection | 9141086 | 20641340 | 20641363 | 14 | - | 27260156 | SKES1 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.32189568092172116 | [521] | [438,613,321,325] | -6 | hSpCas9 | negative selection | 9141087 | 20641273 | 20641296 | 14 | - | 27260156 | SKES1 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.17814306639193417 | [556] | [598,590,415,392] | -4 | hSpCas9 | negative selection | 9141088 | 20640789 | 20640812 | 14 | + | 27260156 | TOV112D | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | -0.3042294033250697 | [568] | [420,690,381,405] | -5 | hSpCas9 | negative selection | 9198081 | 20641313 | 20641336 | 14 | - | 27260156 | TOV112D | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.09097322038581557 | [718] | [679,1080,500,544] | -2 | hSpCas9 | negative selection | 9198082 | 20641643 | 20641666 | 14 | - | 27260156 | TOV112D | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.17979878091230617 | [669] | [1048,883,546,617] | 3 | hSpCas9 | negative selection | 9198083 | 20641639 | 20641662 | 14 | + | 27260156 | TOV112D | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.5868226599620628 | [479] | [608,362,214,132] | -8 | hSpCas9 | negative selection | 9262337 | 20641340 | 20641363 | 14 | - | 27260156 | TOV112D | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.4055205946475541 | [521] | [350,440,403,389] | -7 | hSpCas9 | negative selection | 9262338 | 20641273 | 20641296 | 14 | - | 27260156 | TOV112D | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | -0.20169763491593626 | [556] | [443,547,563,397] | -4 | hSpCas9 | negative selection | 9262339 | 20640789 | 20640812 | 14 | + | 27260156 | TC71 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.16491254038806147 | [568] | [750,671,781,514] | 4 | hSpCas9 | negative selection | 9319332 | 20641313 | 20641336 | 14 | - | 27260156 | TC71 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.16705137490458682 | [718] | [654,736,678,674] | -4 | hSpCas9 | negative selection | 9319333 | 20641643 | 20641666 | 14 | - | 27260156 | TC71 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.18179608053403262 | [669] | [901,802,719,835] | 4 | hSpCas9 | negative selection | 9319334 | 20641639 | 20641662 | 14 | + | 27260156 | TC71 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.27091646523615515 | [479] | [550,456,292,404] | -6 | hSpCas9 | negative selection | 9383588 | 20641340 | 20641363 | 14 | - | 27260156 | TC71 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.0032347839464955674 | [521] | [485,610,529,611] | 0 | hSpCas9 | negative selection | 9383589 | 20641273 | 20641296 | 14 | - | 27260156 | TC71 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.0067646289911937885 | [556] | [572,630,597,597] | 0 | hSpCas9 | negative selection | 9383590 | 20640789 | 20640812 | 14 | + | 27260156 | TC32 | viability | CTTGACTTGCTCATTACGTAAGG | OR6S1 | ENSG00000181803 | 0.35253880864050435 | [568] | [509,710,861,643] | 6 | hSpCas9 | negative selection | 9440583 | 20641313 | 20641336 | 14 | - | 27260156 | TC32 | viability | CATGTCTGCGGATCGCTACCTGG | OR6S1 | ENSG00000181803 | -0.15297424145429644 | [718] | [489,377,853,832] | -3 | hSpCas9 | negative selection | 9440584 | 20641643 | 20641666 | 14 | - | 27260156 | TC32 | viability | TGATCCAACAGAGTTCGTCCTGG | OR6S1 | ENSG00000181803 | 0.3153271910857941 | [669] | [809,570,1014,808] | 5 | hSpCas9 | negative selection | 9440585 | 20641639 | 20641662 | 14 | + | 27260156 | TC32 | viability | CCTGCCAGGACGAACTCTGTTGG | OR6S1 | ENSG00000181803 | -0.2107280410505809 | [479] | [316,360,424,461] | -4 | hSpCas9 | negative selection | 9504839 | 20641340 | 20641363 | 14 | - | 27260156 | TC32 | viability | GGCCTCCGAGTTCTTACTGTTGG | OR6S1 | ENSG00000181803 | -0.10847539909319534 | [521] | [415,335,751,386] | -2 | hSpCas9 | negative selection | 9504840 | 20641273 | 20641296 | 14 | - | 27260156 | TC32 | viability | CGCTACCCCTTGCTCATGAGTGG | OR6S1 | ENSG00000181803 | 0.06967520476264166 | [556] | [550,352,703,664] | 1 | hSpCas9 | negative selection | 9504841 | 20640886 | 20640909 | 14 | - | 27869803 | HPAFII | viability after 27 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 0.09743366744485699 | [202] | [45,170,NaN] | 0 | hSpCas9 | negative selection | 9550885 | 20641053 | 20641076 | 14 | + | 27869803 | HPAFII | viability after 27 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -1.5451072609638605 | [163] | [34,24,NaN] | -7 | hSpCas9 | negative selection | 9550886 | 20641386 | 20641409 | 14 | + | 27869803 | HPAFII | viability after 27 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.2893835855833655 | [626] | [206,321,NaN] | -2 | hSpCas9 | negative selection | 9550887 | 20641610 | 20641633 | 14 | - | 27869803 | HPAFII | viability after 27 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.06605039216706064 | [258] | [123,157,NaN] | 0 | hSpCas9 | negative selection | 9550888 | 20641638 | 20641661 | 14 | - | 27869803 | HPAFII | viability after 27 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.45126606926430735 | [234] | [139,48,NaN] | -3 | hSpCas9 | negative selection | 9550889 | 20640886 | 20640909 | 14 | - | 27869803 | HPAFII | viability after 15 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | -0.06867442449246874 | [202] | [154,240,NaN] | 0 | hSpCas9 | negative selection | 9633334 | 20641053 | 20641076 | 14 | + | 27869803 | HPAFII | viability after 15 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -0.48647334016048993 | [163] | [184,88,NaN] | -5 | hSpCas9 | negative selection | 9633335 | 20641386 | 20641409 | 14 | + | 27869803 | HPAFII | viability after 15 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.30639397445116323 | [626] | [584,519,NaN] | -3 | hSpCas9 | negative selection | 9633336 | 20641610 | 20641633 | 14 | - | 27869803 | HPAFII | viability after 15 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | -0.0712995754094692 | [258] | [259,267,NaN] | 0 | hSpCas9 | negative selection | 9633337 | 20641638 | 20641661 | 14 | - | 27869803 | HPAFII | viability after 15 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -0.5101521307704304 | [234] | [201,161,NaN] | -5 | hSpCas9 | negative selection | 9633338 | 20640886 | 20640909 | 14 | - | 27869803 | ASPC1 | viability after 36 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 0.7740718125878473 | [674] | [624,456,199] | 7 | hSpCas9 | negative selection | 9715783 | 20641053 | 20641076 | 14 | + | 27869803 | ASPC1 | viability after 36 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -0.9960278941521876 | [318] | [79,30,57] | -7 | hSpCas9 | negative selection | 9715784 | 20641386 | 20641409 | 14 | + | 27869803 | ASPC1 | viability after 36 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.3892278929548073 | [1519] | [591,230,407] | -4 | hSpCas9 | negative selection | 9715785 | 20641610 | 20641633 | 14 | - | 27869803 | ASPC1 | viability after 36 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | -0.790539913045823 | [737] | [210,217,48] | -7 | hSpCas9 | negative selection | 9715786 | 20641638 | 20641661 | 14 | - | 27869803 | ASPC1 | viability after 36 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | 0.46049492956571164 | [758] | [217,67,698] | 4 | hSpCas9 | negative selection | 9715787 | 20640886 | 20640909 | 14 | - | 27869803 | PATU8988S | viability after 35 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 0.4053755753606717 | [512] | [335,210,NaN] | 4 | hSpCas9 | negative selection | 9798232 | 20641053 | 20641076 | 14 | + | 27869803 | PATU8988S | viability after 35 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 0.47219607896888843 | [339] | [171,207,NaN] | 5 | hSpCas9 | negative selection | 9798233 | 20641386 | 20641409 | 14 | + | 27869803 | PATU8988S | viability after 35 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.13973812895694915 | [1112] | [353,459,NaN] | -1 | hSpCas9 | negative selection | 9798234 | 20641610 | 20641633 | 14 | - | 27869803 | PATU8988S | viability after 35 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.257371584952318 | [618] | [293,301,NaN] | 3 | hSpCas9 | negative selection | 9798235 | 20641638 | 20641661 | 14 | - | 27869803 | PATU8988S | viability after 35 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | 0.5873540734131044 | [638] | [463,308,NaN] | 6 | hSpCas9 | negative selection | 9798236 | 20640886 | 20640909 | 14 | - | 27869803 | PATU8988S | viability after 31 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | 0.26661875745465785 | [512] | [231,263,NaN] | 3 | hSpCas9 | negative selection | 9880681 | 20641053 | 20641076 | 14 | + | 27869803 | PATU8988S | viability after 31 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | 0.4402647947654731 | [339] | [146,230,NaN] | 5 | hSpCas9 | negative selection | 9880682 | 20641386 | 20641409 | 14 | + | 27869803 | PATU8988S | viability after 31 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.22071608148847066 | [1112] | [397,358,NaN] | -3 | hSpCas9 | negative selection | 9880683 | 20641610 | 20641633 | 14 | - | 27869803 | PATU8988S | viability after 31 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | 0.019358505654075542 | [618] | [232,271,NaN] | 0 | hSpCas9 | negative selection | 9880684 | 20641638 | 20641661 | 14 | - | 27869803 | PATU8988S | viability after 31 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | 0.39636422344989924 | [638] | [337,331,NaN] | 5 | hSpCas9 | negative selection | 9880685 | 20640886 | 20640909 | 14 | - | 27869803 | HPAFII | viability after 35 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | -0.02865378555507797 | [202] | [64,140,NaN] | 0 | hSpCas9 | negative selection | 9963130 | 20641053 | 20641076 | 14 | + | 27869803 | HPAFII | viability after 35 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -0.8876710705514173 | [163] | [26,64,NaN] | -5 | hSpCas9 | negative selection | 9963131 | 20641386 | 20641409 | 14 | + | 27869803 | HPAFII | viability after 35 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.6157547496225415 | [626] | [137,284,NaN] | -4 | hSpCas9 | negative selection | 9963132 | 20641610 | 20641633 | 14 | - | 27869803 | HPAFII | viability after 35 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | -0.34916067951547003 | [258] | [85,121,NaN] | -2 | hSpCas9 | negative selection | 9963133 | 20641638 | 20641661 | 14 | - | 27869803 | HPAFII | viability after 35 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | 0.07899956745809027 | [234] | [159,86,NaN] | 0 | hSpCas9 | negative selection | 9963134 | 20640886 | 20640909 | 14 | - | 27869803 | HPAFII | viability after 31 days | TATGTGCGGCCATCGCAGAGTGG | OR6S1 | ENSG00000181803 | -0.13539454583047789 | [202] | [63,146,NaN] | -1 | hSpCas9 | negative selection | 10045579 | 20641053 | 20641076 | 14 | + | 27869803 | HPAFII | viability after 31 days | GGAAGATACAATGACGAGGGAGG | OR6S1 | ENSG00000181803 | -1.3332273766461435 | [163] | [25,47,NaN] | -7 | hSpCas9 | negative selection | 10045580 | 20641386 | 20641409 | 14 | + | 27869803 | HPAFII | viability after 31 days | TTGGGTGATACATGCAGCAAAGG | OR6S1 | ENSG00000181803 | -0.7532193189439434 | [626] | [169,250,NaN] | -5 | hSpCas9 | negative selection | 10045581 | 20641610 | 20641633 | 14 | - | 27869803 | HPAFII | viability after 31 days | AAATCTCAACAGCGCAAGAGTGG | OR6S1 | ENSG00000181803 | -0.032891917371141235 | [258] | [154,127,NaN] | 0 | hSpCas9 | negative selection | 10045582 | 20641638 | 20641661 | 14 | - | 27869803 | HPAFII | viability after 31 days | CAACAGAGTTCGTCCTGGCAGGG | OR6S1 | ENSG00000181803 | -1.40486499754791 | [234] | [78,17,NaN] | -7 | hSpCas9 | negative selection | 10045583 |