Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5007
• Symbol:OSBP
• Description:oxysterol binding protein

DataSource: http://genomecrispr.dkfz.de/#!/results/OSBP

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
59578186	59578209	11	-	26472758	Jiyoye	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-0.7496934671109926	[164]	[73]	-5	hSpCas9	negative selection	114135
59615534	59615557	11	-	26472758	Jiyoye	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-1.7854696964365226	[31]	[6]	-8	hSpCas9	negative selection	114136
59576808	59576831	11	-	26472758	Jiyoye	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	0.4071753815058734	[78]	[78]	3	hSpCas9	negative selection	114137
59615634	59615657	11	-	26472758	Jiyoye	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-1.5668294099611821	[54]	[13]	-7	hSpCas9	negative selection	114138
59610557	59610580	11	-	26472758	Jiyoye	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.8729325376868622	[50]	[20]	-6	hSpCas9	negative selection	114139
59610522	59610545	11	-	26472758	Jiyoye	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-2.6708271304954	[151]	[17]	-9	hSpCas9	negative selection	114140
59594056	59594079	11	+	26472758	Jiyoye	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-1.2062155275418	[204]	[66]	-7	hSpCas9	negative selection	114141
59593689	59593712	11	+	26472758	Jiyoye	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-3.187771207787905	[144]	[11]	-9	hSpCas9	negative selection	114142
59615600	59615623	11	-	26472758	Jiyoye	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-1.4841183590516267	[114]	[30]	-7	hSpCas9	negative selection	114143
59615563	59615586	11	+	26472758	Jiyoye	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-2.4546273245741075	[377]	[51]	-8	hSpCas9	negative selection	114144
59578186	59578209	11	-	26472758	KBM7	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-0.9907751187055492	[615,519]	[154,114]	-6	hSpCas9	negative selection	305253
59615534	59615557	11	-	26472758	KBM7	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-3.0573380264752257	[112,65]	[5,3]	-9	hSpCas9	negative selection	305254
59576808	59576831	11	-	26472758	KBM7	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-2.318401639606441	[487,456]	[51,37]	-9	hSpCas9	negative selection	305255
59615634	59615657	11	-	26472758	KBM7	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-0.8491267406991213	[233,240]	[73,51]	-6	hSpCas9	negative selection	305256
59610557	59610580	11	-	26472758	KBM7	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.3056377499181573	[370,216]	[50,57]	-7	hSpCas9	negative selection	305257
59610522	59610545	11	-	26472758	KBM7	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-2.3834663032621455	[699,448]	[43,56]	-9	hSpCas9	negative selection	305258
59594056	59594079	11	+	26472758	KBM7	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-1.8908351517456667	[924,962]	[157,86]	-8	hSpCas9	negative selection	305259
59593689	59593712	11	+	26472758	KBM7	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-3.0289968490206496	[354,404]	[9,32]	-9	hSpCas9	negative selection	305260
59615600	59615623	11	-	26472758	KBM7	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-1.4337932523648536	[564,639]	[76,131]	-7	hSpCas9	negative selection	305261
59615563	59615586	11	+	26472758	KBM7	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-1.1598848284379706	[1365,1188]	[329,212]	-7	hSpCas9	negative selection	305262
59578186	59578209	11	-	26472758	Raji	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-0.5285301527943124	[316]	[50]	-4	hSpCas9	negative selection	496371
59615534	59615557	11	-	26472758	Raji	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-3.102069830255351	[73]	[1]	-9	hSpCas9	negative selection	496372
59576808	59576831	11	-	26472758	Raji	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-2.7703607145754026	[293]	[9]	-9	hSpCas9	negative selection	496373
59615634	59615657	11	-	26472758	Raji	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-3.0355744184684434	[211]	[5]	-9	hSpCas9	negative selection	496374
59610557	59610580	11	-	26472758	Raji	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.4846337228815072	[204]	[16]	-8	hSpCas9	negative selection	496375
59610522	59610545	11	-	26472758	Raji	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-2.3355599604751287	[260]	[11]	-9	hSpCas9	negative selection	496376
59594056	59594079	11	+	26472758	Raji	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-2.655117150899744	[379]	[13]	-9	hSpCas9	negative selection	496377
59593689	59593712	11	+	26472758	Raji	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-1.811479701900995	[120]	[7]	-8	hSpCas9	negative selection	496378
59615600	59615623	11	-	26472758	Raji	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-0.726322713630957	[220]	[30]	-5	hSpCas9	negative selection	496379
59615563	59615586	11	+	26472758	Raji	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-1.8056331630317606	[707]	[46]	-8	hSpCas9	negative selection	496380
59578186	59578209	11	-	26472758	K562	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-1.8936975355451895	[470]	[106]	-7	hSpCas9	negative selection	687489
59615534	59615557	11	-	26472758	K562	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-5.588471286498294	[56]	[0]	-9	hSpCas9	negative selection	687490
59576808	59576831	11	-	26472758	K562	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-1.6337401493987556	[260]	[70]	-7	hSpCas9	negative selection	687491
59615634	59615657	11	-	26472758	K562	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-1.9113759449409775	[253]	[56]	-7	hSpCas9	negative selection	687492
59610557	59610580	11	-	26472758	K562	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.335249473385196	[271]	[90]	-6	hSpCas9	negative selection	687493
59610522	59610545	11	-	26472758	K562	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-3.0344406453290294	[329]	[33]	-8	hSpCas9	negative selection	687494
59594056	59594079	11	+	26472758	K562	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-6.601071323277928	[804]	[6]	-9	hSpCas9	negative selection	687495
59593689	59593712	11	+	26472758	K562	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-3.225330181956364	[420]	[37]	-8	hSpCas9	negative selection	687496
59615600	59615623	11	-	26472758	K562	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	0.22037325369979593	[483]	[475]	1	hSpCas9	negative selection	687497
59615563	59615586	11	+	26472758	K562	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-2.1814212677094886	[848]	[157]	-7	hSpCas9	negative selection	687498
59600818	59600841	11	-	26627737	DLD1	viability	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.5478387515979757	[612]	[408,241,199]	5	hSpCas9	negative selection	779279
59601364	59601387	11	-	26627737	DLD1	viability	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-0.7633039100916117	[895]	[200,72,209]	-6	hSpCas9	negative selection	779280
59601727	59601750	11	-	26627737	DLD1	viability	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	-0.3573876905853004	[225]	[83,6,69]	-4	hSpCas9	negative selection	779281
59608645	59608668	11	+	26627737	DLD1	viability	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	-0.3428281645315101	[252]	[69,55,60]	-4	hSpCas9	negative selection	779282
59610525	59610548	11	+	26627737	DLD1	viability	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-4.490370718614772	[1149]	[2,31,13]	-9	hSpCas9	negative selection	779283
59615387	59615410	11	-	26627737	DLD1	viability	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-0.8428173288470986	[192]	[25,10,58]	-7	hSpCas9	negative selection	779284
59600818	59600841	11	-	26627737	GBM cells	viability after 5 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.14684138832927096	[367]	[232,203]	2	hSpCas9	negative selection	861594
59601364	59601387	11	-	26627737	GBM cells	viability after 5 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	0.18842049208067074	[224]	[119,154]	3	hSpCas9	negative selection	861595
59601727	59601750	11	-	26627737	GBM cells	viability after 5 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	0.7595108182202693	[113]	[96,109]	8	hSpCas9	negative selection	861596
59608645	59608668	11	+	26627737	GBM cells	viability after 5 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	-0.10658211286916654	[262]	[116,144]	-2	hSpCas9	negative selection	861597
59610525	59610548	11	+	26627737	GBM cells	viability after 5 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-0.7898234387843213	[352]	[106,111]	-8	hSpCas9	negative selection	861598
59615387	59615410	11	-	26627737	GBM cells	viability after 5 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-0.23858964886424916	[21]	[11,7]	-4	hSpCas9	negative selection	861599
59600818	59600841	11	-	26627737	GBM cells	viability after 13 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.2613152757986795	[367]	[251,228]	3	hSpCas9	negative selection	943909
59601364	59601387	11	-	26627737	GBM cells	viability after 13 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-0.16709914249654215	[224]	[116,101]	-2	hSpCas9	negative selection	943910
59601727	59601750	11	-	26627737	GBM cells	viability after 13 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	0.8374036414680363	[113]	[120,101]	8	hSpCas9	negative selection	943911
59608645	59608668	11	+	26627737	GBM cells	viability after 13 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	-0.09619939727662478	[262]	[154,115]	-1	hSpCas9	negative selection	943912
59610525	59610548	11	+	26627737	GBM cells	viability after 13 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-1.532373530149434	[352]	[79,54]	-9	hSpCas9	negative selection	943913
59615387	59615410	11	-	26627737	GBM cells	viability after 13 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-1.104458502096748	[21]	[4,5]	-8	hSpCas9	negative selection	943914
59600818	59600841	11	-	26627737	GBM cells	viability after 21 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	1.0302748767274224	[367]	[423,393]	8	hSpCas9	negative selection	1026224
59601364	59601387	11	-	26627737	GBM cells	viability after 21 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-0.14709673579402074	[224]	[112,107]	-1	hSpCas9	negative selection	1026225
59601727	59601750	11	-	26627737	GBM cells	viability after 21 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	-0.07436733138335949	[113]	[62,54]	0	hSpCas9	negative selection	1026226
59608645	59608668	11	+	26627737	GBM cells	viability after 21 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	0.1373637733851129	[262]	[176,138]	1	hSpCas9	negative selection	1026227
59610525	59610548	11	+	26627737	GBM cells	viability after 21 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-2.2517769299389614	[352]	[33,45]	-9	hSpCas9	negative selection	1026228
59615387	59615410	11	-	26627737	GBM cells	viability after 21 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-1.799588387446939	[21]	[4,1]	-8	hSpCas9	negative selection	1026229
59600818	59600841	11	-	26627737	RPE1	viability after 9 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	-0.05328956774180127	[1720]	[334,756]	0	hSpCas9	negative selection	1108539
59601364	59601387	11	-	26627737	RPE1	viability after 9 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-1.1679268033627197	[773]	[61,166]	-7	hSpCas9	negative selection	1108540
59601727	59601750	11	-	26627737	RPE1	viability after 9 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	0.3129322730601999	[623]	[267,209]	2	hSpCas9	negative selection	1108541
59608645	59608668	11	+	26627737	RPE1	viability after 9 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	1.1829035682102595	[382]	[197,367]	7	hSpCas9	negative selection	1108542
59610525	59610548	11	+	26627737	RPE1	viability after 9 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-4.07522498510204	[2362]	[18,75]	-9	hSpCas9	negative selection	1108543
59615387	59615410	11	-	26627737	RPE1	viability after 9 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-1.4249244390468776	[218]	[11,42]	-8	hSpCas9	negative selection	1108544
59600818	59600841	11	-	26627737	RPE1	viability after 12 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.16976488365615738	[1720]	[540,497]	1	hSpCas9	negative selection	1190854
59601364	59601387	11	-	26627737	RPE1	viability after 12 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-1.5696180977254577	[773]	[37,103]	-8	hSpCas9	negative selection	1190855
59601727	59601750	11	-	26627737	RPE1	viability after 12 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	0.030248084324674185	[623]	[58,289]	0	hSpCas9	negative selection	1190856
59608645	59608668	11	+	26627737	RPE1	viability after 12 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	0.7989568671742682	[382]	[111,249]	5	hSpCas9	negative selection	1190857
59610525	59610548	11	+	26627737	RPE1	viability after 12 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-4.492669244789278	[2362]	[0,56]	-9	hSpCas9	negative selection	1190858
59615387	59615410	11	-	26627737	RPE1	viability after 12 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-2.0595914332883245	[218]	[17,9]	-8	hSpCas9	negative selection	1190859
59600818	59600841	11	-	26627737	RPE1	viability after 15 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	-0.6480868818113552	[1720]	[160,454]	-4	hSpCas9	negative selection	1273169
59601364	59601387	11	-	26627737	RPE1	viability after 15 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-2.3415872571684426	[773]	[3,80]	-8	hSpCas9	negative selection	1273170
59601727	59601750	11	-	26627737	RPE1	viability after 15 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	0.6182427430654771	[623]	[132,403]	4	hSpCas9	negative selection	1273171
59608645	59608668	11	+	26627737	RPE1	viability after 15 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	0.8620532436788856	[382]	[172,219]	5	hSpCas9	negative selection	1273172
59610525	59610548	11	+	26627737	RPE1	viability after 15 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-4.501680095096405	[2362]	[0,56]	-9	hSpCas9	negative selection	1273173
59615387	59615410	11	-	26627737	RPE1	viability after 15 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-0.6879482349175465	[218]	[40,35]	-4	hSpCas9	negative selection	1273174
59600818	59600841	11	-	26627737	RPE1	viability after 18 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	-0.4210048306968618	[1720]	[270,427]	-3	hSpCas9	negative selection	1355484
59601364	59601387	11	-	26627737	RPE1	viability after 18 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-1.0303471532483521	[773]	[109,93]	-6	hSpCas9	negative selection	1355485
59601727	59601750	11	-	26627737	RPE1	viability after 18 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	0.2592583179925179	[623]	[100,308]	1	hSpCas9	negative selection	1355486
59608645	59608668	11	+	26627737	RPE1	viability after 18 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	-0.0801753097575526	[382]	[61,135]	0	hSpCas9	negative selection	1355487
59610525	59610548	11	+	26627737	RPE1	viability after 18 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-3.431429629882505	[2362]	[3,117]	-9	hSpCas9	negative selection	1355488
59615387	59615410	11	-	26627737	RPE1	viability after 18 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-0.5402970322600791	[218]	[0,82]	-3	hSpCas9	negative selection	1355489
59600818	59600841	11	-	26627737	HeLa	viability after 8 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.26790332622179075	[547]	[416,349,133]	2	hSpCas9	negative selection	1437799
59601364	59601387	11	-	26627737	HeLa	viability after 8 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-0.5203805336350578	[412]	[209,95,90]	-5	hSpCas9	negative selection	1437800
59601727	59601750	11	-	26627737	HeLa	viability after 8 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	0.21000463686976434	[133]	[45,0,144]	2	hSpCas9	negative selection	1437801
59608645	59608668	11	+	26627737	HeLa	viability after 8 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	1.2442581481184578	[156]	[309,162,52]	8	hSpCas9	negative selection	1437802
59610525	59610548	11	+	26627737	HeLa	viability after 8 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-1.4634767526012988	[1118]	[117,239,159]	-9	hSpCas9	negative selection	1437803
59615387	59615410	11	-	26627737	HeLa	viability after 8 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-2.4422023650142655	[345]	[40,1,41]	-9	hSpCas9	negative selection	1437804
59600818	59600841	11	-	26627737	HeLa	viability after 12 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.6672181381208864	[547]	[388,262,437]	5	hSpCas9	negative selection	1520114
59601364	59601387	11	-	26627737	HeLa	viability after 12 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-1.669565758007457	[412]	[49,89,16]	-9	hSpCas9	negative selection	1520115
59601727	59601750	11	-	26627737	HeLa	viability after 12 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	0.7127196500303808	[133]	[4,116,144]	6	hSpCas9	negative selection	1520116
59608645	59608668	11	+	26627737	HeLa	viability after 12 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	1.4744016540149285	[156]	[225,200,112]	8	hSpCas9	negative selection	1520117
59610525	59610548	11	+	26627737	HeLa	viability after 12 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-2.7720650918023684	[1118]	[61,0,146]	-9	hSpCas9	negative selection	1520118
59615387	59615410	11	-	26627737	HeLa	viability after 12 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-2.6178506095296026	[345]	[7,17,43]	-9	hSpCas9	negative selection	1520119
59600818	59600841	11	-	26627737	HeLa	viability after 15 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.946188844575883	[547]	[263,581,446]	7	hSpCas9	negative selection	1602429
59601364	59601387	11	-	26627737	HeLa	viability after 15 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-2.243947543916814	[412]	[100,0,0]	-9	hSpCas9	negative selection	1602430
59601727	59601750	11	-	26627737	HeLa	viability after 15 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	1.2259693550230666	[133]	[107,111,165]	8	hSpCas9	negative selection	1602431
59608645	59608668	11	+	26627737	HeLa	viability after 15 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	1.3915998187521488	[156]	[158,202,138]	8	hSpCas9	negative selection	1602432
59610525	59610548	11	+	26627737	HeLa	viability after 15 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-1.5740465557116696	[1118]	[56,216,188]	-8	hSpCas9	negative selection	1602433
59615387	59615410	11	-	26627737	HeLa	viability after 15 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-3.646032790302816	[345]	[8,22,0]	-9	hSpCas9	negative selection	1602434
59600818	59600841	11	-	26627737	HeLa	viability after 18 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.939159232666877	[547]	[172,481,446]	7	hSpCas9	negative selection	1684744
59601364	59601387	11	-	26627737	HeLa	viability after 18 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-2.3440960575871213	[412]	[62,0,0]	-9	hSpCas9	negative selection	1684745
59601727	59601750	11	-	26627737	HeLa	viability after 18 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	1.2174838809267745	[133]	[61,103,165]	8	hSpCas9	negative selection	1684746
59608645	59608668	11	+	26627737	HeLa	viability after 18 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	1.3668182812115741	[156]	[105,161,138]	8	hSpCas9	negative selection	1684747
59610525	59610548	11	+	26627737	HeLa	viability after 18 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-1.5847037945055038	[1118]	[38,175,188]	-8	hSpCas9	negative selection	1684748
59615387	59615410	11	-	26627737	HeLa	viability after 18 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-3.624726513818457	[345]	[7,16,0]	-9	hSpCas9	negative selection	1684749
59600818	59600841	11	-	26627737	HCT116	viability after 6 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	-0.039022096153361774	[885]	[190,104]	0	hSpCas9	negative selection	1767059
59601364	59601387	11	-	26627737	HCT116	viability after 6 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-1.3877868936047995	[802]	[64,38]	-7	hSpCas9	negative selection	1767060
59601727	59601750	11	-	26627737	HCT116	viability after 6 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	1.14298969770406	[342]	[169,90]	6	hSpCas9	negative selection	1767061
59608645	59608668	11	+	26627737	HCT116	viability after 6 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	0.5076009106370796	[517]	[11,172]	3	hSpCas9	negative selection	1767062
59610525	59610548	11	+	26627737	HCT116	viability after 6 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	0.03354509807293149	[1388]	[305,177]	0	hSpCas9	negative selection	1767063
59615387	59615410	11	-	26627737	HCT116	viability after 6 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-5.869898553920464	[371]	[0,0]	-9	hSpCas9	negative selection	1767064
59600818	59600841	11	-	26627737	HCT116	viability after 8 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.07141323377467323	[444]	[213,368,189]	0	hSpCas9	negative selection	1849374
59601364	59601387	11	-	26627737	HCT116	viability after 8 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-0.5107425303135084	[223]	[94,74,89]	-6	hSpCas9	negative selection	1849375
59601727	59601750	11	-	26627737	HCT116	viability after 8 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	-0.7569645562064384	[367]	[107,68,181]	-7	hSpCas9	negative selection	1849376
59608645	59608668	11	+	26627737	HCT116	viability after 8 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	0.6474511839465958	[192]	[196,194,108]	6	hSpCas9	negative selection	1849377
59610525	59610548	11	+	26627737	HCT116	viability after 8 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-0.5375452663602268	[649]	[191,193,351]	-6	hSpCas9	negative selection	1849378
59615387	59615410	11	-	26627737	HCT116	viability after 8 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-1.1093430849859942	[68]	[16,29,5]	-8	hSpCas9	negative selection	1849379
59600818	59600841	11	-	26627737	HCT116	viability after 9 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.6910175616221004	[885]	[310,437]	5	hSpCas9	negative selection	1931689
59601364	59601387	11	-	26627737	HCT116	viability after 9 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-2.220421888801536	[802]	[2,79]	-9	hSpCas9	negative selection	1931690
59601727	59601750	11	-	26627737	HCT116	viability after 9 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	-0.11550352314094137	[342]	[107,65]	-1	hSpCas9	negative selection	1931691
59608645	59608668	11	+	26627737	HCT116	viability after 9 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	-1.2608010675189316	[517]	[88,32]	-7	hSpCas9	negative selection	1931692
59610525	59610548	11	+	26627737	HCT116	viability after 9 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-0.6058626319800257	[1388]	[360,150]	-4	hSpCas9	negative selection	1931693
59615387	59615410	11	-	26627737	HCT116	viability after 9 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-0.7158429390289338	[371]	[12,97]	-5	hSpCas9	negative selection	1931694
59600818	59600841	11	-	26627737	HCT116	viability after 12 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.3634816058462317	[444]	[323,359,217]	3	hSpCas9	negative selection	2014004
59601364	59601387	11	-	26627737	HCT116	viability after 12 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	0.2725920863133562	[223]	[243,114,57]	3	hSpCas9	negative selection	2014005
59601727	59601750	11	-	26627737	HCT116	viability after 12 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	-1.7071494669967509	[367]	[46,68,62]	-9	hSpCas9	negative selection	2014006
59608645	59608668	11	+	26627737	HCT116	viability after 12 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	0.7369766595635492	[192]	[87,240,186]	6	hSpCas9	negative selection	2014007
59610525	59610548	11	+	26627737	HCT116	viability after 12 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-0.7684446987292941	[649]	[89,352,171]	-7	hSpCas9	negative selection	2014008
59615387	59615410	11	-	26627737	HCT116	viability after 12 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-3.151407604525128	[68]	[5,0,4]	-9	hSpCas9	negative selection	2014009
59600818	59600841	11	-	26627737	HCT116	viability after 15 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.19330603310611716	[444]	[210,385,269]	2	hSpCas9	negative selection	2096319
59601364	59601387	11	-	26627737	HCT116	viability after 15 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-0.4875059361474259	[223]	[133,103,42]	-5	hSpCas9	negative selection	2096320
59601727	59601750	11	-	26627737	HCT116	viability after 15 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	-0.802520302702328	[367]	[149,93,122]	-7	hSpCas9	negative selection	2096321
59608645	59608668	11	+	26627737	HCT116	viability after 15 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	0.46808103629066256	[192]	[191,146,125]	4	hSpCas9	negative selection	2096322
59610525	59610548	11	+	26627737	HCT116	viability after 15 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-0.9185145659520753	[649]	[27,275,266]	-7	hSpCas9	negative selection	2096323
59615387	59615410	11	-	26627737	HCT116	viability after 15 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-1.4634888727666673	[68]	[36,5,2]	-8	hSpCas9	negative selection	2096324
59600818	59600841	11	-	26627737	HCT116	viability after 18 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.040750253845111106	[444]	[250,173,242]	0	hSpCas9	negative selection	2178634
59601364	59601387	11	-	26627737	HCT116	viability after 18 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-0.2192859849770099	[223]	[92,144,34]	-2	hSpCas9	negative selection	2178635
59601727	59601750	11	-	26627737	HCT116	viability after 18 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	-1.4303582215848567	[367]	[30,54,114]	-8	hSpCas9	negative selection	2178636
59608645	59608668	11	+	26627737	HCT116	viability after 18 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	0.22735922684728643	[192]	[64,81,185]	2	hSpCas9	negative selection	2178637
59610525	59610548	11	+	26627737	HCT116	viability after 18 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-1.163558718693558	[649]	[18,222,174]	-8	hSpCas9	negative selection	2178638
59615387	59615410	11	-	26627737	HCT116	viability after 18 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-0.16759693995462577	[68]	[4,14,71]	-1	hSpCas9	negative selection	2178639
59597778	59597801	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCTGCCTCCAGG	OSBP	ENSG00000110048	0.3736894149735144	[619,564]	[67,277]	1	dCas9-VP64	positive selection	2444046
59579558	59579581	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGCGGATCACCTGAGGTCGGG	OSBP	ENSG00000110048	8.572613315975907	[14,15]	[366,2389]	9	dCas9-VP64	positive selection	2455577
59597778	59597801	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCTGCCTCCAGG	OSBP	ENSG00000110048	2.2699980135687987	[309,268]	[879,61]	8	dCas9-VP64	positive selection	2539301
59579558	59579581	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGCGGATCACCTGAGGTCGGG	OSBP	ENSG00000110048	1.5525228181942226	[88,74]	[56,98]	8	dCas9-VP64	positive selection	2550832
59615539	59615562	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCCTGGCCCCGCATCTCCGCGG	OSBP	ENSG00000110048	-1.013725481289706	[3,3]	[1,0]	-9	hSpCas9	positive selection	3008966
59601666	59601689	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTGTTTGCCGGCAGCACCGTGG	OSBP	ENSG00000110048	0.037862104325824854	[3,3]	[2,3]	0	hSpCas9	positive selection	3008967
59610490	59610513	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAACTTCATCATTTCCAATGGG	OSBP	ENSG00000110048	0.12902796958211432	[4,3]	[5,2]	2	hSpCas9	positive selection	3008968
59608656	59608679	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTGCTAGAGAGGGTCCGAAGGG	OSBP	ENSG00000110048	-0.05257477098860988	[4,4]	[4,1]	0	hSpCas9	positive selection	3008969
59615539	59615562	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCCTGGCCCCGCATCTCCGCGG	OSBP	ENSG00000110048	0.32483896056273165	[3,3]	[5,1]	6	hSpCas9	positive selection	3076824
59601666	59601689	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTGTTTGCCGGCAGCACCGTGG	OSBP	ENSG00000110048	0.46953705411246655	[3,3]	[4,2]	7	hSpCas9	positive selection	3076825
59610490	59610513	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAACTTCATCATTTCCAATGGG	OSBP	ENSG00000110048	-0.6390694673901216	[4,4]	[3,0]	-8	hSpCas9	positive selection	3076826
59608656	59608679	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTGCTAGAGAGGGTCCGAAGGG	OSBP	ENSG00000110048	0.5900385525369752	[4,4]	[4,4]	8	hSpCas9	positive selection	3076827
59608508	59608531		-	24336571	A375	resistance to PLX after 7 days	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	-0.2111946951116741	[33,31]	[27,28]	-6	hSpCas9	positive selection	3133319
59610557	59610580		-	24336571	A375	resistance to PLX after 7 days	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	0.08998180450535975	[2,3]	[3,3]	3	hSpCas9	positive selection	3133320
59610544	59610567		+	24336571	A375	resistance to PLX after 7 days	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.0705456629542145	[5,5]	[5,5]	-2	hSpCas9	positive selection	3133321
59608579	59608602		-	24336571	A375	resistance to PLX after 7 days	GCAGCGTTCTCTCAGTGAGCTGG	OSBP	ENSG00000110048	-0.03318910909786815	[9,8]	[8,8]	-1	hSpCas9	positive selection	3133322
59608508	59608531		-	24336571	A375	resistance to PLX after 14 days	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.8960870271313108	[35,26]	[24,28]	7	hSpCas9	positive selection	3191112
59610557	59610580		-	24336571	A375	resistance to PLX after 14 days	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	0.5972506993475208	[4,1]	[1,1]	5	hSpCas9	positive selection	3191113
59610544	59610567		+	24336571	A375	resistance to PLX after 14 days	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.621364532920878	[8,6]	[1,1]	-7	hSpCas9	positive selection	3191114
59608579	59608602		-	24336571	A375	resistance to PLX after 14 days	GCAGCGTTCTCTCAGTGAGCTGG	OSBP	ENSG00000110048	0.3884575516956965	[7,10]	[6,4]	4	hSpCas9	positive selection	3191115
59608508	59608531		-	24336571	A375	viability after 7 days	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.6680409268069042	[21]	[33,31]	8	hSpCas9	negative selection	3248905
59610557	59610580		-	24336571	A375	viability after 7 days	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.823927450047154	[6]	[2,3]	-8	hSpCas9	negative selection	3248906
59610544	59610567		+	24336571	A375	viability after 7 days	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.37347212451109624	[7]	[5,5]	-5	hSpCas9	negative selection	3248907
59608579	59608602		-	24336571	A375	viability after 7 days	GCAGCGTTCTCTCAGTGAGCTGG	OSBP	ENSG00000110048	-0.6045997977307626	[14]	[9,8]	-7	hSpCas9	negative selection	3248908
59608508	59608531		-	24336571	A375	viability after 14 days	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.6016854257443399	[21]	[35,26]	7	hSpCas9	negative selection	3306698
59610557	59610580		-	24336571	A375	viability after 14 days	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.944800194818516	[6]	[4,1]	-8	hSpCas9	negative selection	3306699
59610544	59610567		+	24336571	A375	viability after 14 days	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	0.05925903150589651	[7]	[8,6]	0	hSpCas9	negative selection	3306700
59608579	59608602		-	24336571	A375	viability after 14 days	GCAGCGTTCTCTCAGTGAGCTGG	OSBP	ENSG00000110048	-0.5085245480973174	[14]	[7,10]	-6	hSpCas9	negative selection	3306701
59610557	59610580	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	1.148801754667666	[68,68]	[0,0]	5	hSpCas9	positive selection	3384159
59610544	59610567	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	1.5024387092823666	[53,53]	[0,0]	6	hSpCas9	positive selection	3384160
59601370	59601393	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.01879819382840228	[154,154]	[0,0]	0	hSpCas9	positive selection	3384161
59615538	59615561	11	+	26780180	HT29	viability (Avana library 4 designs)	AGCCTGGCCCCGCATCTCCGCGG	OSBP	ENSG00000110048	2.63458079751358	[]	[]	8	hSpCas9	negative selection	3446974
59601665	59601688	11	+	26780180	HT29	viability (Avana library 4 designs)	AGTGTTTGCCGGCAGCACCGTGG	OSBP	ENSG00000110048	1.4706330571996	[]	[]	6	hSpCas9	negative selection	3446975
59610490	59610513	11	-	26780180	HT29	viability (Avana library 4 designs)	GCAACTTCATCATTTCCAATGGG	OSBP	ENSG00000110048	-0.123360685085984	[]	[]	-2	hSpCas9	negative selection	3446976
59608655	59608678	11	+	26780180	HT29	viability (Avana library 4 designs)	TTTGCTAGAGAGGGTCCGAAGGG	OSBP	ENSG00000110048	1.04765777612567	[]	[]	4	hSpCas9	negative selection	3446977
59608655	59608678	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGCTAGAGAGGGTCCGAAGGG	OSBP	ENSG00000110048	3.26267542593225	[]	[]	5	hSpCas9	negative selection	3540558
59601665	59601688	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGTTTGCCGGCAGCACCGTGG	OSBP	ENSG00000110048	-2.44514331915207	[]	[]	-3	hSpCas9	negative selection	3540559
59615538	59615561	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCCTGGCCCCGCATCTCCGCGG	OSBP	ENSG00000110048	-3.06480260244928	[]	[]	-4	hSpCas9	negative selection	3540560
59610490	59610513	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAACTTCATCATTTCCAATGGG	OSBP	ENSG00000110048	-5.66014420974108	[]	[]	-6	hSpCas9	negative selection	3540561
59610522	59610545	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-9.71920653514197	[]	[]	-7	hSpCas9	negative selection	3540562
59615321	59615344	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGATGGTTCGTGCTGAGCAACGG	OSBP	ENSG00000110048	-9.884472274186	[]	[]	-7	hSpCas9	negative selection	3540563
59608655	59608678	11	+	26780180	A375	viability (Avana lentiGuide)	TTTGCTAGAGAGGGTCCGAAGGG	OSBP	ENSG00000110048	-1.59960597986994	[]	[]	-3	hSpCas9	negative selection	3649217
59601665	59601688	11	+	26780180	A375	viability (Avana lentiGuide)	AGTGTTTGCCGGCAGCACCGTGG	OSBP	ENSG00000110048	11.3446739057788	[]	[]	7	hSpCas9	negative selection	3649218
59615538	59615561	11	+	26780180	A375	viability (Avana lentiGuide)	AGCCTGGCCCCGCATCTCCGCGG	OSBP	ENSG00000110048	20.0297602003027	[]	[]	8	hSpCas9	negative selection	3649219
59610490	59610513	11	-	26780180	A375	viability (Avana lentiGuide)	GCAACTTCATCATTTCCAATGGG	OSBP	ENSG00000110048	-8.68273809385902	[]	[]	-9	hSpCas9	negative selection	3649220
59610522	59610545	11	-	26780180	A375	viability (Avana lentiGuide)	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	18.5916021992513	[]	[]	8	hSpCas9	negative selection	3649221
59615321	59615344	11	-	26780180	A375	viability (Avana lentiGuide)	CGATGGTTCGTGCTGAGCAACGG	OSBP	ENSG00000110048	13.8075046374178	[]	[]	7	hSpCas9	negative selection	3649222
59608655	59608678	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGCTAGAGAGGGTCCGAAGGG	OSBP	ENSG00000110048	0.07155338136325036	[5]	[5,4]	1	hSpCas9	positive selection	3757876
59601665	59601688	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGTTTGCCGGCAGCACCGTGG	OSBP	ENSG00000110048	-0.535896070387953	[5]	[4,2]	-6	hSpCas9	positive selection	3757877
59615538	59615561	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCCTGGCCCCGCATCTCCGCGG	OSBP	ENSG00000110048	-0.47990600205774137	[4]	[3,1]	-6	hSpCas9	positive selection	3757878
59610490	59610513	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAACTTCATCATTTCCAATGGG	OSBP	ENSG00000110048	-0.13559951073582166	[5]	[4,4]	-2	hSpCas9	positive selection	3757879
59610522	59610545	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-1.3175732859687201	[2]	[0,0]	-9	hSpCas9	positive selection	3757880
59615321	59615344	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGATGGTTCGTGCTGAGCAACGG	OSBP	ENSG00000110048	-1.3226899191940287	[4]	[2,0]	-9	hSpCas9	positive selection	3757881
59608655	59608678	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGCTAGAGAGGGTCCGAAGGG	OSBP	ENSG00000110048	-0.1465271607841983	[5]	[2,5]	-2	hSpCas9	positive selection	3866483
59601665	59601688	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGTTTGCCGGCAGCACCGTGG	OSBP	ENSG00000110048	-1.4452747374381942	[5]	[1,0]	-9	hSpCas9	positive selection	3866484
59615538	59615561	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCCTGGCCCCGCATCTCCGCGG	OSBP	ENSG00000110048	-0.32496740272765023	[4]	[4,1]	-4	hSpCas9	positive selection	3866485
59610490	59610513	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAACTTCATCATTTCCAATGGG	OSBP	ENSG00000110048	0.42234078845817286	[5]	[5,5]	9	hSpCas9	positive selection	3866486
59610522	59610545	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-1.7127174259576905	[2]	[0,0]	-9	hSpCas9	positive selection	3866487
59615321	59615344	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGATGGTTCGTGCTGAGCAACGG	OSBP	ENSG00000110048	-0.9989023929954228	[5]	[3,0]	-8	hSpCas9	positive selection	3866488
59601748	59601771	11	-	26780180	A375	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	1.29857510622918	[]	[]	7	hSpCas9	negative selection	3977391
59608508	59608531	11	-	26780180	A375	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.0916583556718814	[]	[]	0	hSpCas9	negative selection	3977392
59601370	59601393	11	-	26780180	A375	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	1.43207898415819	[]	[]	8	hSpCas9	negative selection	3977393
59610557	59610580	11	-	26780180	A375	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	1.59576599528405	[]	[]	8	hSpCas9	negative selection	3977394
59610544	59610567	11	+	26780180	A375	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	2.20637737327326	[]	[]	9	hSpCas9	negative selection	3977395
59601742	59601765	11	+	26780180	A375	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	1.40614024354696	[]	[]	7	hSpCas9	negative selection	3977396
59601748	59601771	11	-	26780180	HT29	viability (GeCKOv2 library)	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	1.53713068254652	[]	[]	7	hSpCas9	negative selection	4085357
59608508	59608531	11	-	26780180	HT29	viability (GeCKOv2 library)	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	-0.0985248093018094	[]	[]	-3	hSpCas9	negative selection	4085358
59601370	59601393	11	-	26780180	HT29	viability (GeCKOv2 library)	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	0.929761291500513	[]	[]	4	hSpCas9	negative selection	4085359
59610557	59610580	11	-	26780180	HT29	viability (GeCKOv2 library)	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	2.02993677757868	[]	[]	9	hSpCas9	negative selection	4085360
59610544	59610567	11	+	26780180	HT29	viability (GeCKOv2 library)	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	2.40509669513019	[]	[]	9	hSpCas9	negative selection	4085361
59601742	59601765	11	+	26780180	HT29	viability (GeCKOv2 library)	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.852973249307581	[]	[]	3	hSpCas9	negative selection	4085362
59608508	59608531	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.2211165286998289	[4]	[2,4]	5	hSpCas9	positive selection	4158136
59610557	59610580	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.67885231183532	[2]	[0,0]	-9	hSpCas9	positive selection	4158137
59610544	59610567	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.315993849607876	[2]	[0,0]	-6	hSpCas9	positive selection	4158138
59608579	59608602	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGCGTTCTCTCAGTGAGCTGG	OSBP	ENSG00000110048	-0.03573926332091905	[3]	[1,2]	-1	hSpCas9	positive selection	4158139
59608508	59608531	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	1.1343439751453852	[4]	[4,4,5,4]	8	hSpCas9	positive selection	4222158
59610557	59610580	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	0.015102172803708583	[3]	[2,2,0,0]	0	hSpCas9	positive selection	4222159
59610544	59610567	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.5673966759159739	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4222160
59608579	59608602	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGCGTTCTCTCAGTGAGCTGG	OSBP	ENSG00000110048	-0.20066683570590205	[3]	[3,0,0,0]	-3	hSpCas9	positive selection	4222161
59601748	59601771	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.9555820849376035	[2]	[0,0]	-9	hSpCas9	positive selection	4288286
59601742	59601765	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-0.8071176528111867	[2]	[1,0]	-9	hSpCas9	positive selection	4288287
59608508	59608531	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.3856471323766858	[3]	[4,3]	7	hSpCas9	positive selection	4288288
59610557	59610580	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.0947510764053251	[2]	[2,0]	-2	hSpCas9	positive selection	4352541
59610544	59610567	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.21997615666570802	[3]	[2,1]	-4	hSpCas9	positive selection	4352542
59601370	59601393	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.6696408885080102	[3]	[2,0]	-9	hSpCas9	positive selection	4352543
59601743	59601765	11	+	27760321	OCIAML3	viability	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-1.3632818773937736	[629,605]	[195,177]	-8	hSpCas9	negative selection	4424773
59608655	59608677	11	+	27760321	OCIAML3	viability	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	-0.7213645041986061	[547,541]	[227,299]	-6	hSpCas9	negative selection	4424774
59615338	59615360	11	-	27760321	OCIAML3	viability	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-2.0984461911355288	[521,386]	[83,79]	-9	hSpCas9	negative selection	4424775
59615510	59615532	11	+	27760321	OCIAML3	viability	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	-1.099337669419418	[543,420]	[140,218]	-7	hSpCas9	negative selection	4424776
59600865	59600887	11	-	27760321	OCIAML3	viability	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	-0.2579038964939587	[565,459]	[282,399]	-3	hSpCas9	negative selection	4424777
59601743	59601765	11	+	27760321	OCIAML2	viability	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-0.6078851033731674	[629,605]	[262,414]	-6	hSpCas9	negative selection	4508236
59608655	59608677	11	+	27760321	OCIAML2	viability	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	-0.053220872295549726	[547,541]	[366,503]	0	hSpCas9	negative selection	4508237
59615338	59615360	11	-	27760321	OCIAML2	viability	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-1.9244115395643144	[521,386]	[95,95]	-9	hSpCas9	negative selection	4508238
59615510	59615532	11	+	27760321	OCIAML2	viability	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	-0.7106564527292597	[543,420]	[162,333]	-6	hSpCas9	negative selection	4508239
59600865	59600887	11	-	27760321	OCIAML2	viability	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	-0.4157930560770453	[565,459]	[261,371]	-5	hSpCas9	negative selection	4508240
59601743	59601765	11	+	27760321	MV411	viability	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.19266350935818188	[629,605]	[553,335]	1	hSpCas9	negative selection	4591699
59608655	59608677	11	+	27760321	MV411	viability	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	0.23751977996949353	[547,541]	[437,405]	1	hSpCas9	negative selection	4591700
59615338	59615360	11	-	27760321	MV411	viability	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-0.06625797584242771	[521,386]	[175,445]	0	hSpCas9	negative selection	4591701
59615510	59615532	11	+	27760321	MV411	viability	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	-1.2669497334483688	[543,420]	[80,206]	-7	hSpCas9	negative selection	4591702
59600865	59600887	11	-	27760321	MV411	viability	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	0.3117738238618494	[565,459]	[188,761]	2	hSpCas9	negative selection	4591703
59601743	59601765	11	+	27760321	HL60	viability	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-1.1415170087386572	[629,605]	[252,203]	-8	hSpCas9	negative selection	4675162
59608655	59608677	11	+	27760321	HL60	viability	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	0.5073252385355347	[547,541]	[521,753]	6	hSpCas9	negative selection	4675163
59615338	59615360	11	-	27760321	HL60	viability	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-2.032976348447219	[521,386]	[86,92]	-9	hSpCas9	negative selection	4675164
59615510	59615532	11	+	27760321	HL60	viability	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	-0.7046380577891885	[543,420]	[193,288]	-6	hSpCas9	negative selection	4675165
59600865	59600887	11	-	27760321	HL60	viability	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	-0.34070229269854946	[565,459]	[434,216]	-4	hSpCas9	negative selection	4675166
59601743	59601765	11	+	27760321	HT1080	viability	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-1.2329863461915749	[605,472]	[68,115]	-5	hSpCas9	negative selection	4758625
59608655	59608677	11	+	27760321	HT1080	viability	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	-7.023552177772575	[541,422]	[0,1]	-9	hSpCas9	negative selection	4758626
59615338	59615360	11	-	27760321	HT1080	viability	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-1.379646713587004	[386,301]	[99,0]	-5	hSpCas9	negative selection	4758627
59615510	59615532	11	+	27760321	HT1080	viability	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	-0.2410254477762681	[420,328]	[92,162]	-1	hSpCas9	negative selection	4758628
59600865	59600887	11	-	27760321	HT1080	viability	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	0.48257175502786287	[459,358]	[352,90]	2	hSpCas9	negative selection	4758629
59601743	59601765	11	+	27760321	HT29	viability after 7 days	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-0.820486520333078	[605,472]	[540,331,327]	-8	hSpCas9	negative selection	4842088
59608655	59608677	11	+	27760321	HT29	viability after 7 days	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	-0.5278501949587557	[541,422]	[533,404,367]	-6	hSpCas9	negative selection	4842089
59615338	59615360	11	-	27760321	HT29	viability after 7 days	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	0.1039948837942069	[386,301]	[553,391,491]	1	hSpCas9	negative selection	4842090
59615510	59615532	11	+	27760321	HT29	viability after 7 days	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	0.17024068581729934	[420,328]	[521,495,603]	2	hSpCas9	negative selection	4842091
59600865	59600887	11	-	27760321	HT29	viability after 7 days	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	-0.222689449842686	[459,358]	[647,345,388]	-3	hSpCas9	negative selection	4842092
59601743	59601765	11	+	27760321	HT29	viability after 25 days	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-2.532992071102099	[605,472]	[80,38,211]	-8	hSpCas9	negative selection	4925551
59608655	59608677	11	+	27760321	HT29	viability after 25 days	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	0.7364074677420992	[541,422]	[965,923,854]	8	hSpCas9	negative selection	4925552
59615338	59615360	11	-	27760321	HT29	viability after 25 days	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-4.206891880344975	[386,301]	[5,27,31]	-9	hSpCas9	negative selection	4925553
59615510	59615532	11	+	27760321	HT29	viability after 25 days	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	0.9086253906895828	[420,328]	[660,934,827]	9	hSpCas9	negative selection	4925554
59600865	59600887	11	-	27760321	HT29	viability after 25 days	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	0.9275405264976384	[459,358]	[1016,779,860]	9	hSpCas9	negative selection	4925555
59601743	59601765	11	+	27760321	HT29	viability after 22 days	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-2.935695776512598	[605,472]	[160,40,39]	-8	hSpCas9	negative selection	5009014
59608655	59608677	11	+	27760321	HT29	viability after 22 days	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	0.1544441480805464	[541,422]	[577,830,452]	1	hSpCas9	negative selection	5009015
59615338	59615360	11	-	27760321	HT29	viability after 22 days	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-7.63526826191121	[386,301]	[1,2,0]	-9	hSpCas9	negative selection	5009016
59615510	59615532	11	+	27760321	HT29	viability after 22 days	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	1.176945195567348	[420,328]	[1168,1268,492]	9	hSpCas9	negative selection	5009017
59600865	59600887	11	-	27760321	HT29	viability after 22 days	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	0.21866228298381263	[459,358]	[796,501,344]	2	hSpCas9	negative selection	5009018
59601743	59601765	11	+	27760321	HT29	viability after 19 days	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-2.261318937757656	[605,472]	[157,153,78]	-8	hSpCas9	negative selection	5092477
59608655	59608677	11	+	27760321	HT29	viability after 19 days	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	0.2968206854089047	[541,422]	[730,636,670]	3	hSpCas9	negative selection	5092478
59615338	59615360	11	-	27760321	HT29	viability after 19 days	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-5.15313365475196	[386,301]	[33,0,0]	-9	hSpCas9	negative selection	5092479
59615510	59615532	11	+	27760321	HT29	viability after 19 days	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	1.1343766906560473	[420,328]	[701,1289,811]	9	hSpCas9	negative selection	5092480
59600865	59600887	11	-	27760321	HT29	viability after 19 days	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	0.15401173371119947	[459,358]	[745,252,584]	1	hSpCas9	negative selection	5092481
59601743	59601765	11	+	27760321	HT29	viability after 16 days	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-2.3982339759356246	[605,472]	[102,167,69]	-8	hSpCas9	negative selection	5175940
59608655	59608677	11	+	27760321	HT29	viability after 16 days	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	0.3423390354297229	[541,422]	[740,661,655]	4	hSpCas9	negative selection	5175941
59615338	59615360	11	-	27760321	HT29	viability after 16 days	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-5.960547023527887	[386,301]	[10,6,0]	-9	hSpCas9	negative selection	5175942
59615510	59615532	11	+	27760321	HT29	viability after 16 days	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	0.5543249951472845	[420,328]	[795,552,517]	6	hSpCas9	negative selection	5175943
59600865	59600887	11	-	27760321	HT29	viability after 16 days	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	0.49263742632249086	[459,358]	[577,700,646]	5	hSpCas9	negative selection	5175944
59601743	59601765	11	+	27760321	HT29	viability after 13 days	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-1.940587538631839	[605,472]	[235,141,113]	-8	hSpCas9	negative selection	5259403
59608655	59608677	11	+	27760321	HT29	viability after 13 days	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	-0.19275401278937215	[541,422]	[410,545,510]	-2	hSpCas9	negative selection	5259404
59615338	59615360	11	-	27760321	HT29	viability after 13 days	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-2.0437837845498508	[386,301]	[177,39,73]	-8	hSpCas9	negative selection	5259405
59615510	59615532	11	+	27760321	HT29	viability after 13 days	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	0.4200424516096038	[420,328]	[436,870,446]	5	hSpCas9	negative selection	5259406
59600865	59600887	11	-	27760321	HT29	viability after 13 days	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	0.28544953554166713	[459,358]	[735,582,426]	3	hSpCas9	negative selection	5259407
59601743	59601765	11	+	27760321	HT29	viability after 10 days	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-0.890995742184403	[605,472]	[464,344,280]	-7	hSpCas9	negative selection	5342866
59608655	59608677	11	+	27760321	HT29	viability after 10 days	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	-0.17900516165703398	[541,422]	[469,633,495]	-2	hSpCas9	negative selection	5342867
59615338	59615360	11	-	27760321	HT29	viability after 10 days	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-0.3912138476213764	[386,301]	[325,291,363]	-5	hSpCas9	negative selection	5342868
59615510	59615532	11	+	27760321	HT29	viability after 10 days	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	0.5691120524830241	[420,328]	[825,816,449]	7	hSpCas9	negative selection	5342869
59600865	59600887	11	-	27760321	HT29	viability after 10 days	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	0.11709229665095727	[459,358]	[676,510,475]	1	hSpCas9	negative selection	5342870
59601743	59601765	11	+	27760321	MOLM13	viability	TTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-1.1402087257215456	[629,605]	[232,94]	-6	hSpCas9	negative selection	5426329
59608655	59608677	11	+	27760321	MOLM13	viability	TTTGCTAGAGAGGGTCCGAAGG	OSBP	ENSG00000110048	0.2372905899619711	[547,541]	[551,202]	1	hSpCas9	negative selection	5426330
59615338	59615360	11	-	27760321	MOLM13	viability	CAAAGGCTACCAGCGGCGATGG	OSBP	ENSG00000110048	-2.976066909806124	[521,386]	[34,29]	-9	hSpCas9	negative selection	5426331
59615510	59615532	11	+	27760321	MOLM13	viability	GCGACCACCGTCCCTGACGCGG	OSBP	ENSG00000110048	-1.8889866048256934	[543,420]	[32,106]	-8	hSpCas9	negative selection	5426332
59600865	59600887	11	-	27760321	MOLM13	viability	CCCATCTGTACAGACGTACTGG	OSBP	ENSG00000110048	-0.38919106830548367	[565,459]	[120,303]	-3	hSpCas9	negative selection	5426333
59615673	59615696	11	+	27661255	K562	viability	GCCGCCTGGAGATACAAGACCGG	OSBP	ENSG00000110048	0.3856052029902337	[343,411]	[410,377]	9	dCas9-KRAB	negative selection	5499543
59615719	59615742	11	+	27661255	K562	viability	GCCGCCCGGAGCGCCCCACACGG	OSBP	ENSG00000110048	0.10077925952768996	[400,342]	[372,273]	3	dCas9-KRAB	negative selection	5499544
59615847	59615870	11	+	27661255	K562	viability	GTCACTTGAGGAAGACCCCGCGG	OSBP	ENSG00000110048	-0.18114913518749398	[853,677]	[603,488]	-5	dCas9-KRAB	negative selection	5499545
59615854	59615877	11	+	27661255	K562	viability	GAGGAAGACCCCGCGGATATTGG	OSBP	ENSG00000110048	-0.13476797571865262	[834,900]	[756,522]	-5	dCas9-KRAB	negative selection	5499546
59615387	59615410	11	-	27661255	K562	viability	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	0.10372834143869736	[1029,1236]	[1013,931]	3	dCas9-KRAB	negative selection	5499547
59615698	59615721	11	-	27661255	K562	viability	GCGACGGCGGCTCTCGTAGGCGG	OSBP	ENSG00000110048	0.07827191289816382	[358,421]	[336,320]	2	dCas9-KRAB	negative selection	5499548
59615701	59615724	11	-	27661255	K562	viability	GCGGCGACGGCGGCTCTCGTAGG	OSBP	ENSG00000110048	-0.21148869061580977	[250,223]	[154,171]	-6	dCas9-KRAB	negative selection	5499549
59615723	59615746	11	-	27661255	K562	viability	GTAGCCGTGTGGGGCGCTCCGGG	OSBP	ENSG00000110048	0.22570075394885786	[571,638]	[652,488]	7	dCas9-KRAB	negative selection	5499550
59601748	59601771	11	-	27260156	BXPC3	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.07310378271067242	[220]	[271,183,246,163]	-2	hSpCas9	negative selection	5560746
59601742	59601765	11	+	27260156	BXPC3	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.06568734309198199	[306]	[295,326,315,416]	1	hSpCas9	negative selection	5560747
59608508	59608531	11	-	27260156	BXPC3	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.264114955032685	[826]	[1179,799,925,1264]	6	hSpCas9	negative selection	5560748
59610557	59610580	11	-	27260156	BXPC3	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.6062791496055776	[247]	[131,142,210,204]	-8	hSpCas9	negative selection	5625001
59610544	59610567	11	+	27260156	BXPC3	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.8467907945931445	[463]	[334,226,255,251]	-9	hSpCas9	negative selection	5625002
59601370	59601393	11	-	27260156	BXPC3	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.7303599026777455	[746]	[426,454,439,575]	-9	hSpCas9	negative selection	5625003
59601748	59601771	11	-	27260156	A673	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.5610183628080201	[220]	[229,126,162,207]	-8	hSpCas9	negative selection	5681997
59601742	59601765	11	+	27260156	A673	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.21488562588247478	[306]	[508,338,372,505]	5	hSpCas9	negative selection	5681998
59608508	59608531	11	-	27260156	A673	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.15513813564805923	[826]	[1180,1098,1104,1040]	3	hSpCas9	negative selection	5681999
59610557	59610580	11	-	27260156	A673	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.3910559455446815	[247]	[217,204,214,271]	-7	hSpCas9	negative selection	5746252
59610544	59610567	11	+	27260156	A673	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.8203783563016981	[463]	[337,301,372,246]	-9	hSpCas9	negative selection	5746253
59601370	59601393	11	-	27260156	A673	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.5909569096326039	[746]	[693,621,618,447]	-8	hSpCas9	negative selection	5746254
59601748	59601771	11	-	27260156	A375	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.7031542437536906	[220]	[112,237,205,94]	-7	hSpCas9	negative selection	5803248
59601742	59601765	11	+	27260156	A375	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.3954087913837692	[306]	[491,571,364,469]	6	hSpCas9	negative selection	5803249
59608508	59608531	11	-	27260156	A375	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.4252752688710594	[826]	[1403,1509,1310,1021]	6	hSpCas9	negative selection	5803250
59610557	59610580	11	-	27260156	A375	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.9763290386871152	[247]	[98,194,82,209]	-8	hSpCas9	negative selection	5867503
59610544	59610567	11	+	27260156	A375	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.0350419517953287	[463]	[332,205,215,290]	-8	hSpCas9	negative selection	5867504
59601370	59601393	11	-	27260156	A375	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.5068276819928867	[746]	[661,502,856,437]	-6	hSpCas9	negative selection	5867505
59601748	59601771	11	-	27260156	COLO741	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.53293652993353	[220]	[224,201,162]	-8	hSpCas9	negative selection	5924499
59601742	59601765	11	+	27260156	COLO741	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.36275693016008376	[306]	[575,632,322]	7	hSpCas9	negative selection	5924500
59608508	59608531	11	-	27260156	COLO741	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.031084834448113496	[826]	[1245,849,1148]	0	hSpCas9	negative selection	5924501
59610557	59610580	11	-	27260156	COLO741	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.6060424489196551	[247]	[259,168,199]	-8	hSpCas9	negative selection	5988754
59610544	59610567	11	+	27260156	COLO741	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.8140572793545974	[463]	[354,426,237]	-9	hSpCas9	negative selection	5988755
59601370	59601393	11	-	27260156	COLO741	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.450905450289856	[746]	[774,743,588]	-7	hSpCas9	negative selection	5988756
59601748	59601771	11	-	27260156	CAL120	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.19062052004125163	[220]	[262,214,247]	-3	hSpCas9	negative selection	6045750
59601742	59601765	11	+	27260156	CAL120	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.2523399963082316	[306]	[505,432,433]	4	hSpCas9	negative selection	6045751
59608508	59608531	11	-	27260156	CAL120	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.39698763708832374	[826]	[1554,1029,1506]	6	hSpCas9	negative selection	6045752
59610557	59610580	11	-	27260156	CAL120	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.6149612748235905	[247]	[287,158,170]	-7	hSpCas9	negative selection	6110005
59610544	59610567	11	+	27260156	CAL120	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.9835799212333597	[463]	[459,195,245]	-8	hSpCas9	negative selection	6110006
59601370	59601393	11	-	27260156	CAL120	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.2505635362733854	[746]	[703,784,841]	-4	hSpCas9	negative selection	6110007
59601748	59601771	11	-	27260156	CADOES1	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.8920082652618466	[220]	[85,130,118,106]	-9	hSpCas9	negative selection	6167001
59601742	59601765	11	+	27260156	CADOES1	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.26995440517082225	[306]	[336,345,378,313]	4	hSpCas9	negative selection	6167002
59608508	59608531	11	-	27260156	CADOES1	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.4359821831641916	[826]	[1167,835,1126,1029]	7	hSpCas9	negative selection	6167003
59610557	59610580	11	-	27260156	CADOES1	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.9619301194256439	[247]	[101,106,111,153]	-9	hSpCas9	negative selection	6231256
59610544	59610567	11	+	27260156	CADOES1	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.1325369203989404	[463]	[192,157,194,242]	-9	hSpCas9	negative selection	6231257
59601370	59601393	11	-	27260156	CADOES1	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.53033698641134	[746]	[529,604,316,471]	-7	hSpCas9	negative selection	6231258
59601748	59601771	11	-	27260156	EWS502	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.7241097654624558	[220]	[175,129,181,69]	-8	hSpCas9	negative selection	6288252
59601742	59601765	11	+	27260156	EWS502	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.4184613945658925	[306]	[443,465,478,338]	7	hSpCas9	negative selection	6288253
59608508	59608531	11	-	27260156	EWS502	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.6299165160070016	[826]	[1446,1397,1212,1342]	9	hSpCas9	negative selection	6288254
59610557	59610580	11	-	27260156	EWS502	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.595367895523624	[247]	[152,181,222,136]	-7	hSpCas9	negative selection	6352507
59610544	59610567	11	+	27260156	EWS502	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.4032820352298983	[463]	[137,275,160,167]	-9	hSpCas9	negative selection	6352508
59601370	59601393	11	-	27260156	EWS502	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.9508290770163006	[746]	[322,419,460,444]	-8	hSpCas9	negative selection	6352509
59601748	59601771	11	-	27260156	EW8	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.7131340319599975	[220]	[144,139,96,60]	-8	hSpCas9	negative selection	6409503
59601742	59601765	11	+	27260156	EW8	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.40541543288539317	[306]	[399,413,267,253]	7	hSpCas9	negative selection	6409504
59608508	59608531	11	-	27260156	EW8	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.2620405966782363	[826]	[817,929,647,844]	5	hSpCas9	negative selection	6409505
59610557	59610580	11	-	27260156	EW8	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.5970700054559005	[247]	[129,230,105,68]	-8	hSpCas9	negative selection	6473758
59610544	59610567	11	+	27260156	EW8	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.7034338442859973	[463]	[140,118,99,106]	-9	hSpCas9	negative selection	6473759
59601370	59601393	11	-	27260156	EW8	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.7498851930520676	[746]	[364,255,363,452]	-8	hSpCas9	negative selection	6473760
59601748	59601771	11	-	27260156	CORL105	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.40004627896552347	[220]	[107,283,161,219]	-6	hSpCas9	negative selection	6530754
59601742	59601765	11	+	27260156	CORL105	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.10748106459566198	[306]	[331,519,377,312]	2	hSpCas9	negative selection	6530755
59608508	59608531	11	-	27260156	CORL105	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.3766689918428251	[826]	[1341,1059,1332,1310]	7	hSpCas9	negative selection	6530756
59610557	59610580	11	-	27260156	CORL105	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.8454138365539355	[247]	[160,101,172,212]	-9	hSpCas9	negative selection	6595009
59610544	59610567	11	+	27260156	CORL105	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.9753424527443594	[463]	[368,225,173,323]	-9	hSpCas9	negative selection	6595010
59601370	59601393	11	-	27260156	CORL105	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.8652470614918158	[746]	[498,439,489,493]	-9	hSpCas9	negative selection	6595011
59601748	59601771	11	-	27260156	HS294T	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-1.0256918807580968	[220]	[30,26,50,63]	-9	hSpCas9	negative selection	6652005
59601742	59601765	11	+	27260156	HS294T	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.28909812843647265	[306]	[107,152,111,222]	4	hSpCas9	negative selection	6652006
59608508	59608531	11	-	27260156	HS294T	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.3654485182035775	[826]	[481,282,426,459]	5	hSpCas9	negative selection	6652007
59610557	59610580	11	-	27260156	HS294T	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.604938576423267	[247]	[35,70,70,78]	-7	hSpCas9	negative selection	6716260
59610544	59610567	11	+	27260156	HS294T	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.4536625154385108	[463]	[40,38,89,100]	-9	hSpCas9	negative selection	6716261
59601370	59601393	11	-	27260156	HS294T	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.6522070757838727	[746]	[112,138,216,291]	-7	hSpCas9	negative selection	6716262
59601748	59601771	11	-	27260156	HCC44	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.38705416940247916	[220]	[241,64,283,209]	-6	hSpCas9	negative selection	6773256
59601742	59601765	11	+	27260156	HCC44	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.48308902269836695	[306]	[800,299,554,352]	7	hSpCas9	negative selection	6773257
59608508	59608531	11	-	27260156	HCC44	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.23888167422319617	[826]	[1302,675,1040,1442]	4	hSpCas9	negative selection	6773258
59610557	59610580	11	-	27260156	HCC44	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.0196327579700184	[247]	[130,98,270,80]	-8	hSpCas9	negative selection	6837511
59610544	59610567	11	+	27260156	HCC44	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.2767190563453905	[463]	[244,215,245,166]	-9	hSpCas9	negative selection	6837512
59601370	59601393	11	-	27260156	HCC44	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.30582557765254076	[746]	[1009,263,852,718]	-5	hSpCas9	negative selection	6837513
59601748	59601771	11	-	27260156	G402	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-1.484388616637455	[220]	[145,129,79,40]	-9	hSpCas9	negative selection	6894507
59601742	59601765	11	+	27260156	G402	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.48000838131243917	[306]	[354,836,240,642]	6	hSpCas9	negative selection	6894508
59608508	59608531	11	-	27260156	G402	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.48458016166490536	[826]	[1754,1406,1764,794]	6	hSpCas9	negative selection	6894509
59610557	59610580	11	-	27260156	G402	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.8606577956452371	[247]	[208,130,205,125]	-7	hSpCas9	negative selection	6958762
59610544	59610567	11	+	27260156	G402	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.9451641966357853	[463]	[296,159,112,44]	-9	hSpCas9	negative selection	6958763
59601370	59601393	11	-	27260156	G402	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.7997617232013758	[746]	[716,578,398,432]	-7	hSpCas9	negative selection	6958764
59601748	59601771	11	-	27260156	L33	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.11692692286489526	[220]	[157,58,202,191]	-3	hSpCas9	negative selection	7015758
59601742	59601765	11	+	27260156	L33	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.017984958748725854	[306]	[264,147,166,351]	0	hSpCas9	negative selection	7015759
59608508	59608531	11	-	27260156	L33	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.03837002730002925	[826]	[689,313,566,1040]	0	hSpCas9	negative selection	7015760
59610557	59610580	11	-	27260156	L33	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.3612218672572537	[247]	[182,65,142,200]	-7	hSpCas9	negative selection	7080013
59610544	59610567	11	+	27260156	L33	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.6165451044191248	[463]	[300,112,170,360]	-8	hSpCas9	negative selection	7080014
59601370	59601393	11	-	27260156	L33	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.2473628195873961	[746]	[639,226,420,652]	-5	hSpCas9	negative selection	7080015
59601748	59601771	11	-	27260156	K562	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-1.2715018286318847	[220]	[104,65,122,36]	-8	hSpCas9	negative selection	7137009
59601742	59601765	11	+	27260156	K562	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.3386410701022575	[306]	[529,275,433,168]	4	hSpCas9	negative selection	7137010
59608508	59608531	11	-	27260156	K562	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.22941166626919374	[826]	[812,1071,905,675]	3	hSpCas9	negative selection	7137011
59610557	59610580	11	-	27260156	K562	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.9520665219452921	[247]	[172,69,155,63]	-8	hSpCas9	negative selection	7201264
59610544	59610567	11	+	27260156	K562	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.833148431654805	[463]	[158,96,32,168]	-9	hSpCas9	negative selection	7201265
59601370	59601393	11	-	27260156	K562	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.6051159307577785	[746]	[478,422,507,344]	-6	hSpCas9	negative selection	7201266
59601748	59601771	11	-	27260156	HT29	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-1.201482823157106	[220]	[146,74,133,109]	-9	hSpCas9	negative selection	7258260
59601742	59601765	11	+	27260156	HT29	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.3131142320275401	[306]	[530,485,365,473]	6	hSpCas9	negative selection	7258261
59608508	59608531	11	-	27260156	HT29	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.24402573592351884	[826]	[1300,1284,1215,992]	5	hSpCas9	negative selection	7258262
59610557	59610580	11	-	27260156	HT29	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.5178513793746559	[247]	[184,225,280,154]	-7	hSpCas9	negative selection	7322515
59610544	59610567	11	+	27260156	HT29	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.2042610112641228	[463]	[202,392,209,187]	-9	hSpCas9	negative selection	7322516
59601370	59601393	11	-	27260156	HT29	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.6223756386735478	[746]	[779,503,672,425]	-8	hSpCas9	negative selection	7322517
59601748	59601771	11	-	27260156	MHHES1	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.247552103372211	[220]	[168,209,315,148]	-5	hSpCas9	negative selection	7379511
59601742	59601765	11	+	27260156	MHHES1	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.3401252303087614	[306]	[395,688,253,423]	6	hSpCas9	negative selection	7379512
59608508	59608531	11	-	27260156	MHHES1	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.2896335334409793	[826]	[1333,1360,919,991]	5	hSpCas9	negative selection	7379513
59610557	59610580	11	-	27260156	MHHES1	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.8205852751479027	[247]	[179,127,179,143]	-9	hSpCas9	negative selection	7443766
59610544	59610567	11	+	27260156	MHHES1	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.8707757838801248	[463]	[384,252,434,113]	-9	hSpCas9	negative selection	7443767
59601370	59601393	11	-	27260156	MHHES1	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.5199038134572305	[746]	[863,682,658,250]	-7	hSpCas9	negative selection	7443768
59601748	59601771	11	-	27260156	MEWO	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.6295324369222457	[220]	[200,124,87]	-8	hSpCas9	negative selection	7500762
59601742	59601765	11	+	27260156	MEWO	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.25015814502662487	[306]	[394,354,284]	5	hSpCas9	negative selection	7500763
59608508	59608531	11	-	27260156	MEWO	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.1468316150450688	[826]	[1008,679,910]	3	hSpCas9	negative selection	7500764
59610557	59610580	11	-	27260156	MEWO	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.5694888902864464	[247]	[166,170,132]	-8	hSpCas9	negative selection	7565017
59610544	59610567	11	+	27260156	MEWO	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.8313639142792222	[463]	[306,253,182]	-9	hSpCas9	negative selection	7565018
59601370	59601393	11	-	27260156	MEWO	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.4888865672703262	[746]	[555,519,428]	-8	hSpCas9	negative selection	7565019
59601748	59601771	11	-	27260156	LNCAPCLONEFGC	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.2706376335921017	[220]	[154,113,257,153]	-4	hSpCas9	negative selection	7622013
59601742	59601765	11	+	27260156	LNCAPCLONEFGC	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.5161152338421662	[306]	[439,327,482,355]	7	hSpCas9	negative selection	7622014
59608508	59608531	11	-	27260156	LNCAPCLONEFGC	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.6675526319711825	[826]	[1326,958,1334,1171]	9	hSpCas9	negative selection	7622015
59610557	59610580	11	-	27260156	LNCAPCLONEFGC	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.2938160935438733	[247]	[234,115,281,117]	-4	hSpCas9	negative selection	7686268
59610544	59610567	11	+	27260156	LNCAPCLONEFGC	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.8771533147849756	[463]	[206,208,262,242]	-8	hSpCas9	negative selection	7686269
59601370	59601393	11	-	27260156	LNCAPCLONEFGC	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.6473632016943559	[746]	[461,283,640,380]	-7	hSpCas9	negative selection	7686270
59601748	59601771	11	-	27260156	PANC0327	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.20570628674861036	[220]	[158,171,293,54]	-3	hSpCas9	negative selection	7743264
59601742	59601765	11	+	27260156	PANC0327	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.07016611691309638	[306]	[387,326,159,272]	1	hSpCas9	negative selection	7743265
59608508	59608531	11	-	27260156	PANC0327	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.1539331188482177	[826]	[1133,642,950,589]	2	hSpCas9	negative selection	7743266
59610557	59610580	11	-	27260156	PANC0327	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.1558402268153136	[247]	[140,42,52,168]	-9	hSpCas9	negative selection	7807519
59610544	59610567	11	+	27260156	PANC0327	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.8926061716640526	[463]	[372,138,172,225]	-8	hSpCas9	negative selection	7807520
59601370	59601393	11	-	27260156	PANC0327	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.4433043663549169	[746]	[802,461,366,348]	-6	hSpCas9	negative selection	7807521
59601748	59601771	11	-	27260156	NCIH2009	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-2.0692516934019163	[220]	[82,43,95]	-9	hSpCas9	negative selection	7864515
59601742	59601765	11	+	27260156	NCIH2009	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.31684750694655245	[306]	[692,439,501]	4	hSpCas9	negative selection	7864516
59608508	59608531	11	-	27260156	NCIH2009	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.2988849558371979	[826]	[1713,1128,1481]	4	hSpCas9	negative selection	7864517
59610557	59610580	11	-	27260156	NCIH2009	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.4444498485821216	[247]	[248,114,41]	-9	hSpCas9	negative selection	7928770
59610544	59610567	11	+	27260156	NCIH2009	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-2.2909021497727338	[463]	[218,93,101]	-9	hSpCas9	negative selection	7928771
59601370	59601393	11	-	27260156	NCIH2009	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-1.0429940344228419	[746]	[642,432,470]	-8	hSpCas9	negative selection	7928772
59601748	59601771	11	-	27260156	NCIH1373	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-1.314572116923089	[220]	[179,50,106,19]	-8	hSpCas9	negative selection	7985766
59601742	59601765	11	+	27260156	NCIH1373	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.6453572780530638	[306]	[821,417,173,214]	6	hSpCas9	negative selection	7985767
59608508	59608531	11	-	27260156	NCIH1373	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.8239945181574527	[826]	[1741,1333,1658,494]	7	hSpCas9	negative selection	7985768
59610557	59610580	11	-	27260156	NCIH1373	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.0992968962129073	[247]	[250,70,36,49]	-8	hSpCas9	negative selection	8050021
59610544	59610567	11	+	27260156	NCIH1373	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.6270634213240076	[463]	[256,115,88,61]	-9	hSpCas9	negative selection	8050022
59601370	59601393	11	-	27260156	NCIH1373	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.47587419481611304	[746]	[541,429,562,235]	-5	hSpCas9	negative selection	8050023
59601748	59601771	11	-	27260156	PATU8902	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.4303220172878186	[220]	[87,174,111,614]	-4	hSpCas9	negative selection	8107017
59601742	59601765	11	+	27260156	PATU8902	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.5061740325355751	[306]	[818,493,285,945]	5	hSpCas9	negative selection	8107018
59608508	59608531	11	-	27260156	PATU8902	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.5178697238725601	[826]	[2004,1498,1086,2198]	5	hSpCas9	negative selection	8107019
59610557	59610580	11	-	27260156	PATU8902	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.12584484156532272	[247]	[213,306,508,166]	-1	hSpCas9	negative selection	8171272
59610544	59610567	11	+	27260156	PATU8902	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.6202306710410707	[463]	[403,390,320,610]	-5	hSpCas9	negative selection	8171273
59601370	59601393	11	-	27260156	PATU8902	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.6710250138294305	[746]	[718,718,351,928]	-6	hSpCas9	negative selection	8171274
59601748	59601771	11	-	27260156	PANC1	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.9695866726621647	[220]	[112,179,70,46]	-8	hSpCas9	negative selection	8228268
59601742	59601765	11	+	27260156	PANC1	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	-0.09406752513250327	[306]	[209,384,285,148]	-1	hSpCas9	negative selection	8228269
59608508	59608531	11	-	27260156	PANC1	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.22567837019187198	[826]	[799,865,857,797]	3	hSpCas9	negative selection	8228270
59610557	59610580	11	-	27260156	PANC1	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.39004899826232864	[247]	[162,329,79,115]	-6	hSpCas9	negative selection	8292523
59610544	59610567	11	+	27260156	PANC1	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.877454811543843	[463]	[55,193,87,111]	-9	hSpCas9	negative selection	8292524
59601370	59601393	11	-	27260156	PANC1	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.37422619332636914	[746]	[448,355,556,569]	-5	hSpCas9	negative selection	8292525
59601748	59601771	11	-	27260156	PANC0813	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.5988537125343667	[220]	[168,135,151,224]	-7	hSpCas9	negative selection	8349519
59601742	59601765	11	+	27260156	PANC0813	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.570353781982458	[306]	[519,493,832,306]	8	hSpCas9	negative selection	8349520
59608508	59608531	11	-	27260156	PANC0813	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.4528972770791123	[826]	[1286,1229,1581,1220]	7	hSpCas9	negative selection	8349521
59610557	59610580	11	-	27260156	PANC0813	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.6461894848156265	[247]	[239,172,148,186]	-7	hSpCas9	negative selection	8413774
59610544	59610567	11	+	27260156	PANC0813	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.6754439247826967	[463]	[545,198,308,329]	-7	hSpCas9	negative selection	8413775
59601370	59601393	11	-	27260156	PANC0813	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.744226763055335	[746]	[667,598,474,373]	-8	hSpCas9	negative selection	8413776
59601748	59601771	11	-	27260156	RDES	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.9396925639182783	[220]	[115,179,115,107]	-9	hSpCas9	negative selection	8470770
59601742	59601765	11	+	27260156	RDES	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.4561628345220377	[306]	[440,301,555,683]	7	hSpCas9	negative selection	8470771
59608508	59608531	11	-	27260156	RDES	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.4127824863920265	[826]	[1082,1416,1192,1367]	6	hSpCas9	negative selection	8470772
59610557	59610580	11	-	27260156	RDES	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.6464573858957429	[247]	[151,149,218,218]	-8	hSpCas9	negative selection	8535025
59610544	59610567	11	+	27260156	RDES	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.0786444173109808	[463]	[163,255,253,365]	-9	hSpCas9	negative selection	8535026
59601370	59601393	11	-	27260156	RDES	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.5806136108079132	[746]	[412,574,724,614]	-7	hSpCas9	negative selection	8535027
59601748	59601771	11	-	27260156	PC3	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	0.22737554274555138	[220]	[162,299,277,313]	5	hSpCas9	negative selection	8592021
59601742	59601765	11	+	27260156	PC3	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.2630920748175605	[306]	[265,244,667,420]	6	hSpCas9	negative selection	8592022
59608508	59608531	11	-	27260156	PC3	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.13028717916172006	[826]	[575,892,1524,911]	3	hSpCas9	negative selection	8592023
59610557	59610580	11	-	27260156	PC3	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.3605174866992563	[247]	[143,127,451,148]	-7	hSpCas9	negative selection	8656276
59610544	59610567	11	+	27260156	PC3	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.6767046787240281	[463]	[231,228,498,271]	-9	hSpCas9	negative selection	8656277
59601370	59601393	11	-	27260156	PC3	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.41964688813819245	[746]	[402,396,966,638]	-7	hSpCas9	negative selection	8656278
59601748	59601771	11	-	27260156	PATU8988T	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-1.118739882269887	[220]	[124,58,131,70]	-9	hSpCas9	negative selection	8713272
59601742	59601765	11	+	27260156	PATU8988T	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.4009216283027654	[306]	[246,484,309,546]	6	hSpCas9	negative selection	8713273
59608508	59608531	11	-	27260156	PATU8988T	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.5796811873186002	[826]	[1255,1276,1143,1100]	8	hSpCas9	negative selection	8713274
59610557	59610580	11	-	27260156	PATU8988T	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.7284020867169373	[247]	[193,122,94,166]	-8	hSpCas9	negative selection	8777527
59610544	59610567	11	+	27260156	PATU8988T	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.5583823046598472	[463]	[350,307,282,273]	-7	hSpCas9	negative selection	8777528
59601370	59601393	11	-	27260156	PATU8988T	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.05950772622600342	[746]	[569,633,734,836]	-1	hSpCas9	negative selection	8777529
59601748	59601771	11	-	27260156	T47D	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.24009874761451333	[220]	[201,204,236,228]	-5	hSpCas9	negative selection	8834523
59601742	59601765	11	+	27260156	T47D	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.2348826372213932	[306]	[380,441,439,417]	5	hSpCas9	negative selection	8834524
59608508	59608531	11	-	27260156	T47D	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.2381513480115368	[826]	[1171,1047,1255,1072]	5	hSpCas9	negative selection	8834525
59610557	59610580	11	-	27260156	T47D	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.256874592125074	[247]	[268,205,235,259]	-5	hSpCas9	negative selection	8898778
59610544	59610567	11	+	27260156	T47D	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.6689311338199289	[463]	[325,258,384,397]	-8	hSpCas9	negative selection	8898779
59601370	59601393	11	-	27260156	T47D	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.42379057106977425	[746]	[734,537,645,686]	-7	hSpCas9	negative selection	8898780
59601748	59601771	11	-	27260156	SU8686	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.9880455165565087	[220]	[77,93,118,164]	-8	hSpCas9	negative selection	8955774
59601742	59601765	11	+	27260156	SU8686	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.07534415108407844	[306]	[281,334,274,402]	1	hSpCas9	negative selection	8955775
59608508	59608531	11	-	27260156	SU8686	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.4807613111401047	[826]	[1056,1210,1024,1297]	7	hSpCas9	negative selection	8955776
59610557	59610580	11	-	27260156	SU8686	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.07024853416428711	[247]	[211,198,260,277]	-1	hSpCas9	negative selection	9020029
59610544	59610567	11	+	27260156	SU8686	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.0325879633368698	[463]	[207,210,242,242]	-8	hSpCas9	negative selection	9020030
59601370	59601393	11	-	27260156	SU8686	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.6699100436750871	[746]	[383,439,500,562]	-7	hSpCas9	negative selection	9020031
59601748	59601771	11	-	27260156	SKES1	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.18082100351298136	[220]	[185,181,241,165]	-4	hSpCas9	negative selection	9077025
59601742	59601765	11	+	27260156	SKES1	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.30999601408194116	[306]	[327,465,497,240]	6	hSpCas9	negative selection	9077026
59608508	59608531	11	-	27260156	SKES1	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.21207504607200323	[826]	[1142,879,846,959]	4	hSpCas9	negative selection	9077027
59610557	59610580	11	-	27260156	SKES1	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.9398908910566496	[247]	[107,147,140,117]	-9	hSpCas9	negative selection	9141280
59610544	59610567	11	+	27260156	SKES1	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.9875043919332803	[463]	[255,266,222,196]	-9	hSpCas9	negative selection	9141281
59601370	59601393	11	-	27260156	SKES1	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.6479638123132586	[746]	[432,484,570,409]	-8	hSpCas9	negative selection	9141282
59601748	59601771	11	-	27260156	TOV112D	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.457301553975757	[220]	[172,295,129,81]	-7	hSpCas9	negative selection	9198276
59601742	59601765	11	+	27260156	TOV112D	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.3089734446449919	[306]	[211,426,241,631]	6	hSpCas9	negative selection	9198277
59608508	59608531	11	-	27260156	TOV112D	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.17372685460690007	[826]	[841,1146,1141,656]	3	hSpCas9	negative selection	9198278
59610557	59610580	11	-	27260156	TOV112D	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.02635092077466	[247]	[125,261,70,64]	-9	hSpCas9	negative selection	9262531
59610544	59610567	11	+	27260156	TOV112D	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-1.1746556091560256	[463]	[233,336,161,126]	-9	hSpCas9	negative selection	9262532
59601370	59601393	11	-	27260156	TOV112D	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.7653681462856132	[746]	[411,644,350,400]	-9	hSpCas9	negative selection	9262533
59601748	59601771	11	-	27260156	TC71	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	-0.21068762546592756	[220]	[159,291,145,224]	-5	hSpCas9	negative selection	9319527
59601742	59601765	11	+	27260156	TC71	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.014622635200435274	[306]	[349,304,321,353]	0	hSpCas9	negative selection	9319528
59608508	59608531	11	-	27260156	TC71	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.32357937287335214	[826]	[972,1018,1283,1161]	7	hSpCas9	negative selection	9319529
59610557	59610580	11	-	27260156	TC71	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.38532990412289003	[247]	[200,203,275,125]	-8	hSpCas9	negative selection	9383782
59610544	59610567	11	+	27260156	TC71	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.6403592083800808	[463]	[367,346,250,310]	-9	hSpCas9	negative selection	9383783
59601370	59601393	11	-	27260156	TC71	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.4032649161365984	[746]	[576,630,542,677]	-8	hSpCas9	negative selection	9383784
59601748	59601771	11	-	27260156	TC32	viability	AAGAGACCAGCGTATCCGACTGG	OSBP	ENSG00000110048	0.05600738540004602	[220]	[119,193,359,222]	1	hSpCas9	negative selection	9440778
59601742	59601765	11	+	27260156	TC32	viability	TTTCTTCCAGTCGGATACGCTGG	OSBP	ENSG00000110048	0.5011507157959679	[306]	[365,287,617,425]	8	hSpCas9	negative selection	9440779
59608508	59608531	11	-	27260156	TC32	viability	ACGAACGAGCCACACTCTTTAGG	OSBP	ENSG00000110048	0.18870937281019085	[826]	[931,586,988,1120]	3	hSpCas9	negative selection	9440780
59610557	59610580	11	-	27260156	TC32	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.6002454624421883	[247]	[178,72,240,155]	-8	hSpCas9	negative selection	9505033
59610544	59610567	11	+	27260156	TC32	viability	GAGGTTGATGGTACCACGGCAGG	OSBP	ENSG00000110048	-0.7715679759633497	[463]	[281,205,286,250]	-9	hSpCas9	negative selection	9505034
59601370	59601393	11	-	27260156	TC32	viability	CTTGTAGATCAGTGCTGCTCTGG	OSBP	ENSG00000110048	-0.41715463155618815	[746]	[415,461,641,613]	-7	hSpCas9	negative selection	9505035
59600818	59600841	11	-	27869803	HPAFII	viability after 27 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.15264701001047673	[272]	[194,129,NaN]	1	hSpCas9	negative selection	9542279
59601364	59601387	11	-	27869803	HPAFII	viability after 27 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-1.1543770779392335	[213]	[73,30,NaN]	-7	hSpCas9	negative selection	9542280
59601727	59601750	11	-	27869803	HPAFII	viability after 27 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	-0.5529127797894233	[137]	[49,48,NaN]	-4	hSpCas9	negative selection	9542281
59608645	59608668	11	+	27869803	HPAFII	viability after 27 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	1.0926397006461999	[143]	[239,95,NaN]	8	hSpCas9	negative selection	9542282
59610525	59610548	11	+	27869803	HPAFII	viability after 27 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-6.000620647478227	[619]	[9,0,NaN]	-9	hSpCas9	negative selection	9542283
59615387	59615410	11	-	27869803	HPAFII	viability after 27 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-3.80131183925482	[134]	[9,0,NaN]	-9	hSpCas9	negative selection	9542284
59600818	59600841	11	-	27869803	HPAFII	viability after 15 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.9254609118529626	[272]	[777,419,NaN]	8	hSpCas9	negative selection	9624728
59601364	59601387	11	-	27869803	HPAFII	viability after 15 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-0.027135747387489223	[213]	[295,181,NaN]	0	hSpCas9	negative selection	9624729
59601727	59601750	11	-	27869803	HPAFII	viability after 15 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	0.2776398893101547	[137]	[209,160,NaN]	3	hSpCas9	negative selection	9624730
59608645	59608668	11	+	27869803	HPAFII	viability after 15 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	1.063312838603316	[143]	[582,161,NaN]	9	hSpCas9	negative selection	9624731
59610525	59610548	11	+	27869803	HPAFII	viability after 15 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-4.888132311316639	[619]	[40,10,NaN]	-9	hSpCas9	negative selection	9624732
59615387	59615410	11	-	27869803	HPAFII	viability after 15 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-3.8373569461034056	[134]	[11,8,NaN]	-9	hSpCas9	negative selection	9624733
59600818	59600841	11	-	27869803	ASPC1	viability after 36 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	-0.005172018420703528	[870]	[532,213,208]	0	hSpCas9	negative selection	9707177
59601364	59601387	11	-	27869803	ASPC1	viability after 36 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-0.5031394257249094	[686]	[207,205,110]	-5	hSpCas9	negative selection	9707178
59601727	59601750	11	-	27869803	ASPC1	viability after 36 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	-0.15186487294138284	[398]	[85,197,93]	-1	hSpCas9	negative selection	9707179
59608645	59608668	11	+	27869803	ASPC1	viability after 36 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	0.782922030467357	[496]	[303,375,229]	7	hSpCas9	negative selection	9707180
59610525	59610548	11	+	27869803	ASPC1	viability after 36 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-1.1842103625766338	[1628]	[114,139,429]	-8	hSpCas9	negative selection	9707181
59615387	59615410	11	-	27869803	ASPC1	viability after 36 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-1.418360452667174	[205]	[8,74,0]	-8	hSpCas9	negative selection	9707182
59600818	59600841	11	-	27869803	PATU8988S	viability after 35 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	-0.26547689660623025	[653]	[274,162,NaN]	-3	hSpCas9	negative selection	9789626
59601364	59601387	11	-	27869803	PATU8988S	viability after 35 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-1.7397570313594999	[546]	[49,81,NaN]	-8	hSpCas9	negative selection	9789627
59601727	59601750	11	-	27869803	PATU8988S	viability after 35 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	0.303827579932356	[342]	[181,158,NaN]	3	hSpCas9	negative selection	9789628
59608645	59608668	11	+	27869803	PATU8988S	viability after 35 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	0.3922315254917961	[501]	[197,332,NaN]	4	hSpCas9	negative selection	9789629
59610525	59610548	11	+	27869803	PATU8988S	viability after 35 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-3.9345126229540917	[1500]	[55,22,NaN]	-9	hSpCas9	negative selection	9789630
59615387	59615410	11	-	27869803	PATU8988S	viability after 35 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-1.5365138526108792	[349]	[88,7,NaN]	-8	hSpCas9	negative selection	9789631
59600818	59600841	11	-	27869803	PATU8988S	viability after 31 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	-0.06063365973519422	[653]	[275,216,NaN]	0	hSpCas9	negative selection	9872075
59601364	59601387	11	-	27869803	PATU8988S	viability after 31 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-1.6621606802350506	[546]	[49,92,NaN]	-8	hSpCas9	negative selection	9872076
59601727	59601750	11	-	27869803	PATU8988S	viability after 31 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	0.9021515709166699	[342]	[259,249,NaN]	8	hSpCas9	negative selection	9872077
59608645	59608668	11	+	27869803	PATU8988S	viability after 31 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	0.27798493773666044	[501]	[170,333,NaN]	3	hSpCas9	negative selection	9872078
59610525	59610548	11	+	27869803	PATU8988S	viability after 31 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-4.230669555306591	[1500]	[30,32,NaN]	-9	hSpCas9	negative selection	9872079
59615387	59615410	11	-	27869803	PATU8988S	viability after 31 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-1.402141593294959	[349]	[76,21,NaN]	-8	hSpCas9	negative selection	9872080
59600818	59600841	11	-	27869803	HPAFII	viability after 35 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	0.1560809240371793	[272]	[145,162,NaN]	1	hSpCas9	negative selection	9954524
59601364	59601387	11	-	27869803	HPAFII	viability after 35 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-0.021379657992074474	[213]	[181,21,NaN]	0	hSpCas9	negative selection	9954525
59601727	59601750	11	-	27869803	HPAFII	viability after 35 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	-0.380871180689089	[137]	[63,41,NaN]	-2	hSpCas9	negative selection	9954526
59608645	59608668	11	+	27869803	HPAFII	viability after 35 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	1.487046636949712	[143]	[312,81,NaN]	8	hSpCas9	negative selection	9954527
59610525	59610548	11	+	27869803	HPAFII	viability after 35 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-4.971537634861189	[619]	[17,0,NaN]	-9	hSpCas9	negative selection	9954528
59615387	59615410	11	-	27869803	HPAFII	viability after 35 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-6.0947270440541566	[134]	[0,0,NaN]	-9	hSpCas9	negative selection	9954529
59600818	59600841	11	-	27869803	HPAFII	viability after 31 days	TGACATCAGCCTTGATGAACAGG	OSBP	ENSG00000110048	-0.07359017352499841	[272]	[102,191,NaN]	0	hSpCas9	negative selection	10036973
59601364	59601387	11	-	27869803	HPAFII	viability after 31 days	GATCAGTGCTGCTCTGGCAAAGG	OSBP	ENSG00000110048	-0.4669301038450642	[213]	[117,52,NaN]	-3	hSpCas9	negative selection	10036974
59601727	59601750	11	-	27869803	HPAFII	viability after 31 days	GGAAGAAACCCTCGAGCAGCTGG	OSBP	ENSG00000110048	-0.02844658481797624	[137]	[107,40,NaN]	0	hSpCas9	negative selection	10036975
59608645	59608668	11	+	27869803	HPAFII	viability after 31 days	AGTCCTCTACTTTGCTAGAGAGG	OSBP	ENSG00000110048	1.6157714433863064	[143]	[340,145,NaN]	9	hSpCas9	negative selection	10036976
59610525	59610548	11	+	27869803	HPAFII	viability after 31 days	CGGTGATGTTGGCTGTGGCGAGG	OSBP	ENSG00000110048	-4.0333622694612785	[619]	[37,2,NaN]	-9	hSpCas9	negative selection	10036977
59615387	59615410	11	-	27869803	HPAFII	viability after 31 days	GGTTCGGGCTCGGCTCGAGAGGG	OSBP	ENSG00000110048	-3.971847978038355	[134]	[0,8,NaN]	-9	hSpCas9	negative selection	10036978
59578186	59578209	11	-	28162770	P31FUJ	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-1.3528019805250087	[212]	[97]	-7	hSpCas9	negative selection	10205117
59615534	59615557	11	-	28162770	P31FUJ	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-6.518204423276627	[77]	[0]	-9	hSpCas9	negative selection	10205118
59576808	59576831	11	-	28162770	P31FUJ	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-1.3719649520860038	[173]	[78]	-7	hSpCas9	negative selection	10205119
59615634	59615657	11	-	28162770	P31FUJ	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-3.4027272058566913	[125]	[13]	-9	hSpCas9	negative selection	10205120
59610557	59610580	11	-	28162770	P31FUJ	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.1547996924131054	[107]	[56]	-7	hSpCas9	negative selection	10205121
59610522	59610545	11	-	28162770	P31FUJ	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-6.268426114145099	[327]	[4]	-9	hSpCas9	negative selection	10205122
59594056	59594079	11	+	28162770	P31FUJ	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-2.8903815084430793	[712]	[112]	-9	hSpCas9	negative selection	10205123
59593689	59593712	11	+	28162770	P31FUJ	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-1.517255593883078	[189]	[77]	-7	hSpCas9	negative selection	10205124
59615600	59615623	11	-	28162770	P31FUJ	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-1.28265075386494	[264]	[127]	-7	hSpCas9	negative selection	10205125
59615563	59615586	11	+	28162770	P31FUJ	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-1.9033404368416087	[954]	[299]	-8	hSpCas9	negative selection	10205126
59578186	59578209	11	-	28162770	TF1	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10374483
59615534	59615557	11	-	28162770	TF1	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10374484
59576808	59576831	11	-	28162770	TF1	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	NaN	[NaN]	[99]	1	hSpCas9	negative selection	10374485
59615634	59615657	11	-	28162770	TF1	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10374486
59610557	59610580	11	-	28162770	TF1	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10374487
59610522	59610545	11	-	28162770	TF1	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10374488
59594056	59594079	11	+	28162770	TF1	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	NaN	[NaN]	[58]	1	hSpCas9	negative selection	10374489
59593689	59593712	11	+	28162770	TF1	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10374490
59615600	59615623	11	-	28162770	TF1	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	NaN	[NaN]	[83]	1	hSpCas9	negative selection	10374491
59615563	59615586	11	+	28162770	TF1	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	NaN	[NaN]	[254]	1	hSpCas9	negative selection	10374492
59578186	59578209	11	-	28162770	SKM1	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-0.03058831983342307	[51]	[89]	0	hSpCas9	negative selection	10543849
59615534	59615557	11	-	28162770	SKM1	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-3.8220016980220053	[7]	[0]	-9	hSpCas9	negative selection	10543850
59576808	59576831	11	-	28162770	SKM1	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-1.4069641987431614	[47]	[31]	-7	hSpCas9	negative selection	10543851
59615634	59615657	11	-	28162770	SKM1	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	0.10399772053421752	[19]	[37]	1	hSpCas9	negative selection	10543852
59610557	59610580	11	-	28162770	SKM1	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.8604758458366413	[37]	[36]	-6	hSpCas9	negative selection	10543853
59610522	59610545	11	-	28162770	SKM1	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-1.2869644226325316	[97]	[70]	-7	hSpCas9	negative selection	10543854
59594056	59594079	11	+	28162770	SKM1	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-3.1912355076877246	[123]	[23]	-9	hSpCas9	negative selection	10543855
59593689	59593712	11	+	28162770	SKM1	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-0.886132035441721	[45]	[43]	-6	hSpCas9	negative selection	10543856
59615600	59615623	11	-	28162770	SKM1	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-0.9192988993769202	[45]	[42]	-6	hSpCas9	negative selection	10543857
59615563	59615586	11	+	28162770	SKM1	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-1.4918530963296748	[209]	[131]	-7	hSpCas9	negative selection	10543858
59578186	59578209	11	-	28162770	SKM1	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-0.03058831983342307	[51]	[89]	0	hSpCas9	negative selection	10713215
59615534	59615557	11	-	28162770	SKM1	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-3.8220016980220053	[7]	[0]	-9	hSpCas9	negative selection	10713216
59576808	59576831	11	-	28162770	SKM1	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-1.4069641987431614	[47]	[31]	-7	hSpCas9	negative selection	10713217
59615634	59615657	11	-	28162770	SKM1	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	0.10399772053421752	[19]	[37]	1	hSpCas9	negative selection	10713218
59610557	59610580	11	-	28162770	SKM1	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.8604758458366413	[37]	[36]	-6	hSpCas9	negative selection	10713219
59610522	59610545	11	-	28162770	SKM1	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-1.2869644226325316	[97]	[70]	-7	hSpCas9	negative selection	10713220
59594056	59594079	11	+	28162770	SKM1	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-3.1912355076877246	[123]	[23]	-9	hSpCas9	negative selection	10713221
59593689	59593712	11	+	28162770	SKM1	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-0.886132035441721	[45]	[43]	-6	hSpCas9	negative selection	10713222
59615600	59615623	11	-	28162770	SKM1	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-0.9192988993769202	[45]	[42]	-6	hSpCas9	negative selection	10713223
59615563	59615586	11	+	28162770	SKM1	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-1.4918530963296748	[209]	[131]	-7	hSpCas9	negative selection	10713224
59578186	59578209	11	-	28162770	PL21	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	0.15433592487619543	[191]	[92]	1	hSpCas9	negative selection	10882581
59615534	59615557	11	-	28162770	PL21	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	0.27814212649059344	[35]	[18]	2	hSpCas9	negative selection	10882582
59576808	59576831	11	-	28162770	PL21	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-0.15184571425422208	[193]	[75]	-1	hSpCas9	negative selection	10882583
59615634	59615657	11	-	28162770	PL21	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-3.00931375113963	[73]	[3]	-9	hSpCas9	negative selection	10882584
59610557	59610580	11	-	28162770	PL21	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.5524228347279043	[154]	[45]	-4	hSpCas9	negative selection	10882585
59610522	59610545	11	-	28162770	PL21	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-2.957074335203438	[338]	[18]	-9	hSpCas9	negative selection	10882586
59594056	59594079	11	+	28162770	PL21	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-0.25754222219801726	[411]	[149]	-2	hSpCas9	negative selection	10882587
59593689	59593712	11	+	28162770	PL21	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-3.788545072282846	[126]	[3]	-9	hSpCas9	negative selection	10882588
59615600	59615623	11	-	28162770	PL21	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-1.4403179988235395	[211]	[33]	-7	hSpCas9	negative selection	10882589
59615563	59615586	11	+	28162770	PL21	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-1.0137046291589082	[616]	[132]	-6	hSpCas9	negative selection	10882590
59578186	59578209	11	-	28162770	P31FUJ	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-1.3528019805250087	[212]	[97]	-7	hSpCas9	negative selection	11051947
59615534	59615557	11	-	28162770	P31FUJ	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-6.518204423276627	[77]	[0]	-9	hSpCas9	negative selection	11051948
59576808	59576831	11	-	28162770	P31FUJ	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-1.3719649520860038	[173]	[78]	-7	hSpCas9	negative selection	11051949
59615634	59615657	11	-	28162770	P31FUJ	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-3.4027272058566913	[125]	[13]	-9	hSpCas9	negative selection	11051950
59610557	59610580	11	-	28162770	P31FUJ	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.1547996924131054	[107]	[56]	-7	hSpCas9	negative selection	11051951
59610522	59610545	11	-	28162770	P31FUJ	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-6.268426114145099	[327]	[4]	-9	hSpCas9	negative selection	11051952
59594056	59594079	11	+	28162770	P31FUJ	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-2.8903815084430793	[712]	[112]	-9	hSpCas9	negative selection	11051953
59593689	59593712	11	+	28162770	P31FUJ	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-1.517255593883078	[189]	[77]	-7	hSpCas9	negative selection	11051954
59615600	59615623	11	-	28162770	P31FUJ	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-1.28265075386494	[264]	[127]	-7	hSpCas9	negative selection	11051955
59615563	59615586	11	+	28162770	P31FUJ	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-1.9033404368416087	[954]	[299]	-8	hSpCas9	negative selection	11051956
59578186	59578209	11	-	28162770	OCIAML5	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-1.1451135457642305	[135]	[110]	-6	hSpCas9	negative selection	11221313
59615534	59615557	11	-	28162770	OCIAML5	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-5.244383993642757	[20]	[0]	-9	hSpCas9	negative selection	11221314
59576808	59576831	11	-	28162770	OCIAML5	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-1.9934224201095383	[74]	[33]	-8	hSpCas9	negative selection	11221315
59615634	59615657	11	-	28162770	OCIAML5	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-3.217716043180677	[66]	[12]	-9	hSpCas9	negative selection	11221316
59610557	59610580	11	-	28162770	OCIAML5	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-2.1558473190411	[78]	[31]	-8	hSpCas9	negative selection	11221317
59610522	59610545	11	-	28162770	OCIAML5	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-2.6594214929216013	[139]	[39]	-8	hSpCas9	negative selection	11221318
59594056	59594079	11	+	28162770	OCIAML5	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-3.521562581796821	[368]	[57]	-9	hSpCas9	negative selection	11221319
59593689	59593712	11	+	28162770	OCIAML5	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-4.758957166472515	[89]	[5]	-9	hSpCas9	negative selection	11221320
59615600	59615623	11	-	28162770	OCIAML5	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-1.661544664814571	[169]	[96]	-7	hSpCas9	negative selection	11221321
59615563	59615586	11	+	28162770	OCIAML5	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-2.5665887053540692	[488]	[148]	-8	hSpCas9	negative selection	11221322
59578186	59578209	11	-	28162770	EOL1	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-2.355088601600389	[436]	[44]	-8	hSpCas9	negative selection	11390679
59615534	59615557	11	-	28162770	EOL1	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-1.5017169831315638	[42]	[7]	-7	hSpCas9	negative selection	11390680
59576808	59576831	11	-	28162770	EOL1	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-2.9775258077402085	[298]	[19]	-9	hSpCas9	negative selection	11390681
59615634	59615657	11	-	28162770	EOL1	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-1.59146737543313	[142]	[24]	-7	hSpCas9	negative selection	11390682
59610557	59610580	11	-	28162770	EOL1	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.1458415563208633	[272]	[64]	-6	hSpCas9	negative selection	11390683
59610522	59610545	11	-	28162770	EOL1	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-2.1992287690678882	[522]	[59]	-8	hSpCas9	negative selection	11390684
59594056	59594079	11	+	28162770	EOL1	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-1.7496820672477091	[599]	[93]	-8	hSpCas9	negative selection	11390685
59593689	59593712	11	+	28162770	EOL1	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-1.339952043267758	[196]	[40]	-7	hSpCas9	negative selection	11390686
59615600	59615623	11	-	28162770	EOL1	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-1.8971149871709532	[303]	[42]	-8	hSpCas9	negative selection	11390687
59615563	59615586	11	+	28162770	EOL1	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-0.17826303401324095	[944]	[439]	-1	hSpCas9	negative selection	11390688
59578186	59578209	11	-	28162770	MOLM13	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-0.9181690507624992	[344]	[131]	-5	hSpCas9	negative selection	11560045
59615534	59615557	11	-	28162770	MOLM13	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-2.24831765245483	[45]	[6]	-7	hSpCas9	negative selection	11560046
59576808	59576831	11	-	28162770	MOLM13	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	0.1643398159720711	[194]	[157]	1	hSpCas9	negative selection	11560047
59615634	59615657	11	-	28162770	MOLM13	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-1.7884503717152067	[128]	[26]	-7	hSpCas9	negative selection	11560048
59610557	59610580	11	-	28162770	MOLM13	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-1.1446853503844374	[210]	[68]	-6	hSpCas9	negative selection	11560049
59610522	59610545	11	-	28162770	MOLM13	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-3.9320412253440566	[379]	[17]	-9	hSpCas9	negative selection	11560050
59594056	59594079	11	+	28162770	MOLM13	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-3.2056670424455658	[637]	[49]	-8	hSpCas9	negative selection	11560051
59593689	59593712	11	+	28162770	MOLM13	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-4.999716168538419	[176]	[3]	-9	hSpCas9	negative selection	11560052
59615600	59615623	11	-	28162770	MOLM13	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-2.9310611335666286	[326]	[30]	-8	hSpCas9	negative selection	11560053
59615563	59615586	11	+	28162770	MOLM13	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-2.2255488370807064	[924]	[142]	-7	hSpCas9	negative selection	11560054
59578186	59578209	11	-	28162770	HEL	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-2.256734292045679	[290]	[38]	-8	hSpCas9	negative selection	11729411
59615534	59615557	11	-	28162770	HEL	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-5.112148670163112	[53]	[0]	-9	hSpCas9	negative selection	11729412
59576808	59576831	11	-	28162770	HEL	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-1.7593596115709886	[221]	[41]	-7	hSpCas9	negative selection	11729413
59615634	59615657	11	-	28162770	HEL	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-4.001117357774367	[99]	[3]	-9	hSpCas9	negative selection	11729414
59610557	59610580	11	-	28162770	HEL	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-2.325552308272305	[179]	[22]	-8	hSpCas9	negative selection	11729415
59610522	59610545	11	-	28162770	HEL	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-2.7935562878390057	[432]	[39]	-8	hSpCas9	negative selection	11729416
59594056	59594079	11	+	28162770	HEL	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-2.9118500196772805	[516]	[43]	-8	hSpCas9	negative selection	11729417
59593689	59593712	11	+	28162770	HEL	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-4.066919416170114	[156]	[5]	-9	hSpCas9	negative selection	11729418
59615600	59615623	11	-	28162770	HEL	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-2.579653589336091	[251]	[26]	-8	hSpCas9	negative selection	11729419
59615563	59615586	11	+	28162770	HEL	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-2.273581176528092	[920]	[121]	-8	hSpCas9	negative selection	11729420
59578186	59578209	11	-	28162770	MV411	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-0.3119898578312432	[167]	[113]	-2	hSpCas9	negative selection	11898777
59615534	59615557	11	-	28162770	MV411	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-5.585452463381966	[56]	[0]	-9	hSpCas9	negative selection	11898778
59576808	59576831	11	-	28162770	MV411	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-0.8026031317168203	[175]	[84]	-5	hSpCas9	negative selection	11898779
59615634	59615657	11	-	28162770	MV411	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-4.12760188056415	[82]	[3]	-9	hSpCas9	negative selection	11898780
59610557	59610580	11	-	28162770	MV411	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	0.6562430963501046	[115]	[153]	6	hSpCas9	negative selection	11898781
59610522	59610545	11	-	28162770	MV411	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-4.545796263030176	[304]	[10]	-9	hSpCas9	negative selection	11898782
59594056	59594079	11	+	28162770	MV411	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-1.4579627282600507	[436]	[133]	-7	hSpCas9	negative selection	11898783
59593689	59593712	11	+	28162770	MV411	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-1.6701002890252514	[135]	[35]	-7	hSpCas9	negative selection	11898784
59615600	59615623	11	-	28162770	MV411	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-0.8735778501785907	[173]	[79]	-5	hSpCas9	negative selection	11898785
59615563	59615586	11	+	28162770	MV411	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-1.988050528165356	[663]	[140]	-8	hSpCas9	negative selection	11898786
59578186	59578209	11	-	28162770	MONOMAC1	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-0.2739988288744378	[153]	[145]	-2	hSpCas9	negative selection	12068143
59615534	59615557	11	-	28162770	MONOMAC1	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-0.7205988031165664	[22]	[15]	-5	hSpCas9	negative selection	12068144
59576808	59576831	11	-	28162770	MONOMAC1	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-0.8523886756721076	[125]	[79]	-6	hSpCas9	negative selection	12068145
59615634	59615657	11	-	28162770	MONOMAC1	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-2.3792401782803028	[58]	[12]	-9	hSpCas9	negative selection	12068146
59610557	59610580	11	-	28162770	MONOMAC1	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	0.234120317582567	[88]	[119]	2	hSpCas9	negative selection	12068147
59610522	59610545	11	-	28162770	MONOMAC1	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-2.928840736109981	[185]	[27]	-9	hSpCas9	negative selection	12068148
59594056	59594079	11	+	28162770	MONOMAC1	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-0.9532270084906583	[276]	[163]	-6	hSpCas9	negative selection	12068149
59593689	59593712	11	+	28162770	MONOMAC1	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-2.47005534146597	[115]	[23]	-9	hSpCas9	negative selection	12068150
59615600	59615623	11	-	28162770	MONOMAC1	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-1.6185006154978303	[149]	[55]	-8	hSpCas9	negative selection	12068151
59615563	59615586	11	+	28162770	MONOMAC1	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-1.9072355316629743	[444]	[135]	-8	hSpCas9	negative selection	12068152
59578186	59578209	11	-	28162770	OCIAML2	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-1.3710941516912465	[41]	[89]	-7	hSpCas9	negative selection	12237509
59615534	59615557	11	-	28162770	OCIAML2	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-3.470629825242161	[9]	[4]	-9	hSpCas9	negative selection	12237510
59576808	59576831	11	-	28162770	OCIAML2	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-1.4045406347843887	[31]	[66]	-7	hSpCas9	negative selection	12237511
59615634	59615657	11	-	28162770	OCIAML2	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-3.190521906049426	[27]	[16]	-9	hSpCas9	negative selection	12237512
59610557	59610580	11	-	28162770	OCIAML2	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-2.367536332278058	[26]	[28]	-8	hSpCas9	negative selection	12237513
59610522	59610545	11	-	28162770	OCIAML2	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-3.775484406770582	[41]	[16]	-9	hSpCas9	negative selection	12237514
59594056	59594079	11	+	28162770	OCIAML2	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	-1.4706298252421615	[64]	[129]	-7	hSpCas9	negative selection	12237515
59593689	59593712	11	+	28162770	OCIAML2	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-0.7336642310759549	[26]	[89]	-5	hSpCas9	negative selection	12237516
59615600	59615623	11	-	28162770	OCIAML2	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-0.3953416979379243	[27]	[117]	-3	hSpCas9	negative selection	12237517
59615563	59615586	11	+	28162770	OCIAML2	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-2.470629825242161	[136]	[136]	-8	hSpCas9	negative selection	12237518
59578186	59578209	11	-	28162770	OCIAML3	viability	ACAGAGAGGCCATGAAGCAGAGG	OSBP	ENSG00000110048	-1.049687124100353	[71]	[104]	-6	hSpCas9	negative selection	12406875
59615534	59615557	11	-	28162770	OCIAML3	viability	GGAGATGCGGGGCCAGGCTCCGG	OSBP	ENSG00000110048	-1.746010733769213	[9]	[8]	-8	hSpCas9	negative selection	12406876
59576808	59576831	11	-	28162770	OCIAML3	viability	GGAAGCTATGAAAGCCACAGAGG	OSBP	ENSG00000110048	-0.48079702987617223	[48]	[105]	-4	hSpCas9	negative selection	12406877
59615634	59615657	11	-	28162770	OCIAML3	viability	GACGGAGCTGAGAGGAGTGGTGG	OSBP	ENSG00000110048	-0.503809831352585	[30]	[65]	-4	hSpCas9	negative selection	12406878
59610557	59610580	11	-	28162770	OCIAML3	viability	GAAATGAGACATACCTGCCGTGG	OSBP	ENSG00000110048	-0.16870180559149206	[34]	[93]	-1	hSpCas9	negative selection	12406879
59610522	59610545	11	-	28162770	OCIAML3	viability	CGCCACAGCCAACATCACCGTGG	OSBP	ENSG00000110048	-3.193920482511291	[96]	[31]	-9	hSpCas9	negative selection	12406880
59594056	59594079	11	+	28162770	OCIAML3	viability	TCAAAGGTCTCCCCAAGCAGTGG	OSBP	ENSG00000110048	0.01661974379034037	[129]	[396]	0	hSpCas9	negative selection	12406881
59593689	59593712	11	+	28162770	OCIAML3	viability	AGCATGGTGCGCAGCAGCAGGGG	OSBP	ENSG00000110048	-1.437888438406881	[34]	[38]	-7	hSpCas9	negative selection	12406882
59615600	59615623	11	-	28162770	OCIAML3	viability	GCAGCCATTGCAGCACTTGGCGG	OSBP	ENSG00000110048	-0.616033946654162	[65]	[129]	-5	hSpCas9	negative selection	12406883
59615563	59615586	11	+	28162770	OCIAML3	viability	GCCGCCTCCTCCCACCACTGGGG	OSBP	ENSG00000110048	-1.1639307415811782	[166]	[224]	-7	hSpCas9	negative selection	12406884