| 39565135 | 39565158 | 1 | - | 26472758 | Jiyoye | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | -3.2366808082688516 | [49] | [3] | -9 | hSpCas9 | negative selection | 115134 | 39575833 | 39575856 | 1 | + | 26472758 | Jiyoye | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | -0.2884311828992752 | [148] | [91] | -2 | hSpCas9 | negative selection | 115135 | 39575786 | 39575809 | 1 | + | 26472758 | Jiyoye | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | -0.14921796701851187 | [49] | [33] | -1 | hSpCas9 | negative selection | 115136 | 39575939 | 39575962 | 1 | - | 26472758 | Jiyoye | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | 0.5812047812809222 | [38] | [43] | 4 | hSpCas9 | negative selection | 115137 | 39575847 | 39575870 | 1 | - | 26472758 | Jiyoye | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -1.1584217943483517 | [73] | [24] | -7 | hSpCas9 | negative selection | 115138 | 39575766 | 39575789 | 1 | + | 26472758 | Jiyoye | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | -1.5714509677015598 | [66] | [16] | -7 | hSpCas9 | negative selection | 115139 | 39565135 | 39565158 | 1 | - | 26472758 | KBM7 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | 0.4365938046863156 | [72,53] | [77,5] | 5 | hSpCas9 | negative selection | 306252 | 39575833 | 39575856 | 1 | + | 26472758 | KBM7 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | -0.01966562071636105 | [713,390] | [214,280] | 0 | hSpCas9 | negative selection | 306253 | 39575786 | 39575809 | 1 | + | 26472758 | KBM7 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | -0.6082922824932393 | [209,140] | [56,49] | -5 | hSpCas9 | negative selection | 306254 | 39575939 | 39575962 | 1 | - | 26472758 | KBM7 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.2933487342396741 | [220,210] | [90,75] | -3 | hSpCas9 | negative selection | 306255 | 39575847 | 39575870 | 1 | - | 26472758 | KBM7 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.9351671588009964 | [170,132] | [44,29] | -6 | hSpCas9 | negative selection | 306256 | 39575766 | 39575789 | 1 | + | 26472758 | KBM7 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | -0.10542500363484053 | [177,91] | [40,71] | -1 | hSpCas9 | negative selection | 306257 | 39565135 | 39565158 | 1 | - | 26472758 | Raji | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | -1.6295820587926066 | [79] | [5] | -8 | hSpCas9 | negative selection | 497370 | 39575833 | 39575856 | 1 | + | 26472758 | Raji | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | -0.11229450126581236 | [176] | [37] | -1 | hSpCas9 | negative selection | 497371 | 39575786 | 39575809 | 1 | + | 26472758 | Raji | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | 0.4713468500581741 | [114] | [36] | 4 | hSpCas9 | negative selection | 497372 | 39575939 | 39575962 | 1 | - | 26472758 | Raji | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.7670855825425416 | [131] | [17] | -5 | hSpCas9 | negative selection | 497373 | 39575847 | 39575870 | 1 | - | 26472758 | Raji | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.07252555464133503 | [144] | [31] | 0 | hSpCas9 | negative selection | 497374 | 39575766 | 39575789 | 1 | + | 26472758 | Raji | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | 0.6923460360947558 | [31] | [11] | 6 | hSpCas9 | negative selection | 497375 | 39565135 | 39565158 | 1 | - | 26472758 | K562 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | -3.258081612862737 | [67] | [5] | -8 | hSpCas9 | negative selection | 688488 | 39575833 | 39575856 | 1 | + | 26472758 | K562 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | 1.2707700546133993 | [216] | [441] | 9 | hSpCas9 | negative selection | 688489 | 39575786 | 39575809 | 1 | + | 26472758 | K562 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | -0.20696061867611748 | [133] | [97] | -1 | hSpCas9 | negative selection | 688490 | 39575939 | 39575962 | 1 | - | 26472758 | K562 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -1.1469027026385894 | [180] | [68] | -6 | hSpCas9 | negative selection | 688491 | 39575847 | 39575870 | 1 | - | 26472758 | K562 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -1.1340928955872829 | [142] | [54] | -6 | hSpCas9 | negative selection | 688492 | 39575766 | 39575789 | 1 | + | 26472758 | K562 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | 0.42813068083883477 | [80] | [91] | 3 | hSpCas9 | negative selection | 688493 | 39564436 | 39564459 | 1 | + | 26627737 | DLD1 | viability | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.005468702984448681 | [162] | [59,64,31] | 0 | hSpCas9 | negative selection | 771292 | 39564694 | 39564717 | 1 | + | 26627737 | DLD1 | viability | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | -0.4417273219712583 | [1431] | [389,266,328] | -4 | hSpCas9 | negative selection | 771293 | 39565126 | 39565149 | 1 | + | 26627737 | DLD1 | viability | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | -0.08102362183152256 | [321] | [99,140,52] | -1 | hSpCas9 | negative selection | 771294 | 39575824 | 39575847 | 1 | + | 26627737 | DLD1 | viability | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.42783021922591336 | [1331] | [264,427,249] | -4 | hSpCas9 | negative selection | 771295 | 39564436 | 39564459 | 1 | + | 26627737 | GBM cells | viability after 5 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.2766152228915567 | [136] | [65,111] | 4 | hSpCas9 | negative selection | 853607 | 39564694 | 39564717 | 1 | + | 26627737 | GBM cells | viability after 5 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.23925400688692833 | [435] | [292,258] | 4 | hSpCas9 | negative selection | 853608 | 39565126 | 39565149 | 1 | + | 26627737 | GBM cells | viability after 5 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | -0.8420815963166735 | [238] | [67,74] | -8 | hSpCas9 | negative selection | 853609 | 39575824 | 39575847 | 1 | + | 26627737 | GBM cells | viability after 5 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.10383673613034883 | [524] | [250,272] | -2 | hSpCas9 | negative selection | 853610 | 39564436 | 39564459 | 1 | + | 26627737 | GBM cells | viability after 13 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.045267475693496095 | [136] | [76,67] | 0 | hSpCas9 | negative selection | 935922 | 39564694 | 39564717 | 1 | + | 26627737 | GBM cells | viability after 13 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.37189585736549924 | [435] | [277,328] | 5 | hSpCas9 | negative selection | 935923 | 39565126 | 39565149 | 1 | + | 26627737 | GBM cells | viability after 13 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | -0.5809504277855155 | [238] | [89,83] | -6 | hSpCas9 | negative selection | 935924 | 39575824 | 39575847 | 1 | + | 26627737 | GBM cells | viability after 13 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.08233210686755499 | [524] | [380,177] | -1 | hSpCas9 | negative selection | 935925 | 39564436 | 39564459 | 1 | + | 26627737 | GBM cells | viability after 21 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.17088825465919133 | [136] | [76,89] | 1 | hSpCas9 | negative selection | 1018237 | 39564694 | 39564717 | 1 | + | 26627737 | GBM cells | viability after 21 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.5049387820887531 | [435] | [332,338] | 5 | hSpCas9 | negative selection | 1018238 | 39565126 | 39565149 | 1 | + | 26627737 | GBM cells | viability after 21 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | -0.18395191503797434 | [238] | [118,109] | -2 | hSpCas9 | negative selection | 1018239 | 39575824 | 39575847 | 1 | + | 26627737 | GBM cells | viability after 21 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.3303807955026319 | [524] | [253,201] | -3 | hSpCas9 | negative selection | 1018240 | 39564436 | 39564459 | 1 | + | 26627737 | RPE1 | viability after 9 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.366883141563878 | [358] | [132,27] | -3 | hSpCas9 | negative selection | 1100552 | 39564694 | 39564717 | 1 | + | 26627737 | RPE1 | viability after 9 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 1.4201232164000814 | [830] | [831,520] | 7 | hSpCas9 | negative selection | 1100553 | 39565126 | 39565149 | 1 | + | 26627737 | RPE1 | viability after 9 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 2.5185932244355933 | [158] | [124,491] | 9 | hSpCas9 | negative selection | 1100554 | 39575824 | 39575847 | 1 | + | 26627737 | RPE1 | viability after 9 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.4995747253333892 | [1381] | [319,287] | -4 | hSpCas9 | negative selection | 1100555 | 39564436 | 39564459 | 1 | + | 26627737 | RPE1 | viability after 12 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.6348899992335377 | [358] | [226,67] | 4 | hSpCas9 | negative selection | 1182867 | 39564694 | 39564717 | 1 | + | 26627737 | RPE1 | viability after 12 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 1.2962659966045313 | [830] | [694,392] | 7 | hSpCas9 | negative selection | 1182868 | 39565126 | 39565149 | 1 | + | 26627737 | RPE1 | viability after 12 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 2.8083325817177256 | [158] | [136,470] | 9 | hSpCas9 | negative selection | 1182869 | 39575824 | 39575847 | 1 | + | 26627737 | RPE1 | viability after 12 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.12401185987985086 | [1381] | [432,242] | -1 | hSpCas9 | negative selection | 1182870 | 39564436 | 39564459 | 1 | + | 26627737 | RPE1 | viability after 15 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.3093742808031147 | [358] | [190,62] | 2 | hSpCas9 | negative selection | 1265182 | 39564694 | 39564717 | 1 | + | 26627737 | RPE1 | viability after 15 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 1.286301123296753 | [830] | [778,374] | 7 | hSpCas9 | negative selection | 1265183 | 39565126 | 39565149 | 1 | + | 26627737 | RPE1 | viability after 15 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 2.562048530742695 | [158] | [202,325] | 9 | hSpCas9 | negative selection | 1265184 | 39575824 | 39575847 | 1 | + | 26627737 | RPE1 | viability after 15 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.09535183562918303 | [1381] | [453,280] | 0 | hSpCas9 | negative selection | 1265185 | 39564436 | 39564459 | 1 | + | 26627737 | RPE1 | viability after 18 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.8372861907704767 | [358] | [277,60] | 5 | hSpCas9 | negative selection | 1347497 | 39564694 | 39564717 | 1 | + | 26627737 | RPE1 | viability after 18 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 1.318682924940451 | [830] | [803,297] | 7 | hSpCas9 | negative selection | 1347498 | 39565126 | 39565149 | 1 | + | 26627737 | RPE1 | viability after 18 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 2.7367522666389483 | [158] | [67,518] | 9 | hSpCas9 | negative selection | 1347499 | 39575824 | 39575847 | 1 | + | 26627737 | RPE1 | viability after 18 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | 0.12038935408918006 | [1381] | [504,298] | 0 | hSpCas9 | negative selection | 1347500 | 39564436 | 39564459 | 1 | + | 26627737 | HeLa | viability after 8 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.12307444958542711 | [386] | [131,180,222] | 1 | hSpCas9 | negative selection | 1429812 | 39564694 | 39564717 | 1 | + | 26627737 | HeLa | viability after 8 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | -0.34293031056597956 | [1107] | [471,343,346] | -3 | hSpCas9 | negative selection | 1429813 | 39565126 | 39565149 | 1 | + | 26627737 | HeLa | viability after 8 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 0.5919897970212703 | [273] | [134,224,169] | 5 | hSpCas9 | negative selection | 1429814 | 39575824 | 39575847 | 1 | + | 26627737 | HeLa | viability after 8 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | 0.0026933485020315118 | [923] | [364,311,514] | 0 | hSpCas9 | negative selection | 1429815 | 39564436 | 39564459 | 1 | + | 26627737 | HeLa | viability after 12 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -1.5946345499579873 | [386] | [26,53,76] | -9 | hSpCas9 | negative selection | 1512127 | 39564694 | 39564717 | 1 | + | 26627737 | HeLa | viability after 12 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.010241252524239242 | [1107] | [574,411,404] | 0 | hSpCas9 | negative selection | 1512128 | 39565126 | 39565149 | 1 | + | 26627737 | HeLa | viability after 12 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 1.4186201061765606 | [273] | [265,274,368] | 8 | hSpCas9 | negative selection | 1512129 | 39575824 | 39575847 | 1 | + | 26627737 | HeLa | viability after 12 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.3533704201233294 | [923] | [114,339,431] | -3 | hSpCas9 | negative selection | 1512130 | 39564436 | 39564459 | 1 | + | 26627737 | HeLa | viability after 15 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.3053883938048498 | [386] | [120,7,263] | -3 | hSpCas9 | negative selection | 1594442 | 39564694 | 39564717 | 1 | + | 26627737 | HeLa | viability after 15 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | -0.3535663683103454 | [1107] | [282,447,326] | -3 | hSpCas9 | negative selection | 1594443 | 39565126 | 39565149 | 1 | + | 26627737 | HeLa | viability after 15 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 0.3766364217317889 | [273] | [72,173,191] | 3 | hSpCas9 | negative selection | 1594444 | 39575824 | 39575847 | 1 | + | 26627737 | HeLa | viability after 15 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | 0.029440636553629718 | [923] | [204,420,539] | 0 | hSpCas9 | negative selection | 1594445 | 39564436 | 39564459 | 1 | + | 26627737 | HeLa | viability after 18 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.27594292872284804 | [386] | [85,6,263] | -2 | hSpCas9 | negative selection | 1676757 | 39564694 | 39564717 | 1 | + | 26627737 | HeLa | viability after 18 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | -0.34570557799770785 | [1107] | [195,367,326] | -3 | hSpCas9 | negative selection | 1676758 | 39565126 | 39565149 | 1 | + | 26627737 | HeLa | viability after 18 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 0.3835756035593384 | [273] | [51,141,191] | 3 | hSpCas9 | negative selection | 1676759 | 39575824 | 39575847 | 1 | + | 26627737 | HeLa | viability after 18 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | 0.0313184289378281 | [923] | [126,362,539] | 0 | hSpCas9 | negative selection | 1676760 | 39564436 | 39564459 | 1 | + | 26627737 | HCT116 | viability after 6 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.33163846310883793 | [494] | [124,82] | 1 | hSpCas9 | negative selection | 1759072 | 39564694 | 39564717 | 1 | + | 26627737 | HCT116 | viability after 6 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.8545315463851121 | [970] | [460,173] | 5 | hSpCas9 | negative selection | 1759073 | 39565126 | 39565149 | 1 | + | 26627737 | HCT116 | viability after 6 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | -0.5237119324656474 | [438] | [18,63] | -3 | hSpCas9 | negative selection | 1759074 | 39575824 | 39575847 | 1 | + | 26627737 | HCT116 | viability after 6 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.26007580761514404 | [1328] | [187,166] | -1 | hSpCas9 | negative selection | 1759075 | 39564436 | 39564459 | 1 | + | 26627737 | HCT116 | viability after 8 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.515255194242487 | [258] | [84,89,123] | -6 | hSpCas9 | negative selection | 1841387 | 39564694 | 39564717 | 1 | + | 26627737 | HCT116 | viability after 8 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | -0.18227918351277717 | [611] | [282,281,325] | -2 | hSpCas9 | negative selection | 1841388 | 39565126 | 39565149 | 1 | + | 26627737 | HCT116 | viability after 8 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 0.012645663018033326 | [269] | [176,144,128] | 0 | hSpCas9 | negative selection | 1841389 | 39575824 | 39575847 | 1 | + | 26627737 | HCT116 | viability after 8 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.3778422583171497 | [458] | [325,124,135] | -4 | hSpCas9 | negative selection | 1841390 | 39564436 | 39564459 | 1 | + | 26627737 | HCT116 | viability after 9 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.8391266478782609 | [494] | [74,72] | -5 | hSpCas9 | negative selection | 1923702 | 39564694 | 39564717 | 1 | + | 26627737 | HCT116 | viability after 9 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 1.6336997902165904 | [970] | [846,770] | 8 | hSpCas9 | negative selection | 1923703 | 39565126 | 39565149 | 1 | + | 26627737 | HCT116 | viability after 9 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 1.9972496292268975 | [438] | [138,727] | 9 | hSpCas9 | negative selection | 1923704 | 39575824 | 39575847 | 1 | + | 26627737 | HCT116 | viability after 9 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -1.1970250554265618 | [1328] | [256,73] | -7 | hSpCas9 | negative selection | 1923705 | 39564436 | 39564459 | 1 | + | 26627737 | HCT116 | viability after 12 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.9309928441804993 | [258] | [48,106,60] | -7 | hSpCas9 | negative selection | 2006017 | 39564694 | 39564717 | 1 | + | 26627737 | HCT116 | viability after 12 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | -0.2877558997133034 | [611] | [189,310,296] | -3 | hSpCas9 | negative selection | 2006018 | 39565126 | 39565149 | 1 | + | 26627737 | HCT116 | viability after 12 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 0.06954041521056376 | [269] | [77,151,222] | 0 | hSpCas9 | negative selection | 2006019 | 39575824 | 39575847 | 1 | + | 26627737 | HCT116 | viability after 12 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | 0.007886084856512765 | [458] | [341,164,209] | 0 | hSpCas9 | negative selection | 2006020 | 39564436 | 39564459 | 1 | + | 26627737 | HCT116 | viability after 15 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.020802016232938036 | [258] | [51,98,287] | 0 | hSpCas9 | negative selection | 2088332 | 39564694 | 39564717 | 1 | + | 26627737 | HCT116 | viability after 15 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.14585092933597443 | [611] | [175,436,525] | 1 | hSpCas9 | negative selection | 2088333 | 39565126 | 39565149 | 1 | + | 26627737 | HCT116 | viability after 15 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | -0.2065043488589783 | [269] | [136,176,89] | -2 | hSpCas9 | negative selection | 2088334 | 39575824 | 39575847 | 1 | + | 26627737 | HCT116 | viability after 15 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | 0.24787632633992074 | [458] | [390,199,356] | 2 | hSpCas9 | negative selection | 2088335 | 39564436 | 39564459 | 1 | + | 26627737 | HCT116 | viability after 18 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.27200222368328353 | [258] | [79,79,154] | -2 | hSpCas9 | negative selection | 2170647 | 39564694 | 39564717 | 1 | + | 26627737 | HCT116 | viability after 18 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.5084123018773943 | [611] | [205,385,684] | 4 | hSpCas9 | negative selection | 2170648 | 39565126 | 39565149 | 1 | + | 26627737 | HCT116 | viability after 18 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | -0.029874093047533634 | [269] | [55,127,202] | 0 | hSpCas9 | negative selection | 2170649 | 39575824 | 39575847 | 1 | + | 26627737 | HCT116 | viability after 18 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | 0.7424095741083925 | [458] | [625,92,414] | 6 | hSpCas9 | negative selection | 2170650 | 39575765 | 39575788 | 1 | - | 24336569 | HL60 | viability | CTACGTCAACTTCCAGCAGCCGG | PABPC4 | ENSG00000090621 | 0.6255819805576498 | [418] | [1367] | 5 | hSpCas9 | negative selection | 2282412 | 39575777 | 39575800 | 1 | + | 24336569 | HL60 | viability | AGTTGACGTAGGCATAGCCCAGG | PABPC4 | ENSG00000090621 | 0.2689450187229542 | [641] | [1636] | 2 | hSpCas9 | negative selection | 2282413 | 39575783 | 39575806 | 1 | + | 24336569 | HL60 | viability | CGTAGGCATAGCCCAGGGAGCGG | PABPC4 | ENSG00000090621 | -0.5160354868889622 | [693] | [1026] | -5 | hSpCas9 | negative selection | 2282414 | 39575794 | 39575817 | 1 | - | 24336569 | HL60 | viability | ATGATCACCCGCCGCTCCCTGGG | PABPC4 | ENSG00000090621 | 3.240463994258466 | [0] | [19] | 9 | hSpCas9 | negative selection | 2282415 | 39575801 | 39575824 | 1 | + | 24336569 | HL60 | viability | AGCGGCGGGTGATCATATCGCGG | PABPC4 | ENSG00000090621 | -1.433826870978047 | [502] | [393] | -8 | hSpCas9 | negative selection | 2282416 | 39575810 | 39575833 | 1 | + | 24336569 | HL60 | viability | TGATCATATCGCGGCAGACCCGG | PABPC4 | ENSG00000090621 | 1.1555750966719531 | [412] | [1946] | 8 | hSpCas9 | negative selection | 2282417 | 39575824 | 39575847 | 1 | + | 24336569 | HL60 | viability | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.8436745743339455 | [931] | [1098] | -6 | hSpCas9 | negative selection | 2282418 | 39575879 | 39575902 | 1 | + | 24336569 | HL60 | viability | CCTCGGTGACGTCCGAATGCAGG | PABPC4 | ENSG00000090621 | 0.5498783353745569 | [703] | [2180] | 5 | hSpCas9 | negative selection | 2282419 | 39575891 | 39575914 | 1 | - | 24336569 | HL60 | viability | GTACGTGGGCGACCTGCATTCGG | PABPC4 | ENSG00000090621 | -0.10960458099339743 | [672] | [1319] | -1 | hSpCas9 | negative selection | 2282420 | 39575904 | 39575927 | 1 | + | 24336569 | HL60 | viability | GCCCACGTACAGGGAGGCCATGG | PABPC4 | ENSG00000090621 | 0.023819369532336987 | [1168] | [2514] | 0 | hSpCas9 | negative selection | 2282421 | 39575765 | 39575788 | 1 | - | 24336569 | KBM7 | viability | CTACGTCAACTTCCAGCAGCCGG | PABPC4 | ENSG00000090621 | -0.7189949761396569 | [655] | [1086] | -5 | hSpCas9 | negative selection | 2349589 | 39575777 | 39575800 | 1 | + | 24336569 | KBM7 | viability | AGTTGACGTAGGCATAGCCCAGG | PABPC4 | ENSG00000090621 | -0.3272427793823617 | [683] | [1486] | -3 | hSpCas9 | negative selection | 2349590 | 39575783 | 39575806 | 1 | + | 24336569 | KBM7 | viability | CGTAGGCATAGCCCAGGGAGCGG | PABPC4 | ENSG00000090621 | -0.3224705131279789 | [711] | [1552] | -3 | hSpCas9 | negative selection | 2349591 | 39575794 | 39575817 | 1 | - | 24336569 | KBM7 | viability | ATGATCACCCGCCGCTCCCTGGG | PABPC4 | ENSG00000090621 | 4.280341258014317 | [0] | [52] | 9 | hSpCas9 | negative selection | 2349592 | 39575801 | 39575824 | 1 | + | 24336569 | KBM7 | viability | AGCGGCGGGTGATCATATCGCGG | PABPC4 | ENSG00000090621 | -0.49545004616800586 | [382] | [740] | -4 | hSpCas9 | negative selection | 2349593 | 39575810 | 39575833 | 1 | + | 24336569 | KBM7 | viability | TGATCATATCGCGGCAGACCCGG | PABPC4 | ENSG00000090621 | -0.4751474565576872 | [633] | [1243] | -4 | hSpCas9 | negative selection | 2349594 | 39575824 | 39575847 | 1 | + | 24336569 | KBM7 | viability | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.691674848401441 | [892] | [1507] | -5 | hSpCas9 | negative selection | 2349595 | 39575879 | 39575902 | 1 | + | 24336569 | KBM7 | viability | CCTCGGTGACGTCCGAATGCAGG | PABPC4 | ENSG00000090621 | 0.5159645908674759 | [530] | [2070] | 5 | hSpCas9 | negative selection | 2349596 | 39575891 | 39575914 | 1 | - | 24336569 | KBM7 | viability | GTACGTGGGCGACCTGCATTCGG | PABPC4 | ENSG00000090621 | 1.0649241121655786 | [278] | [1591] | 8 | hSpCas9 | negative selection | 2349597 | 39575904 | 39575927 | 1 | + | 24336569 | KBM7 | viability | GCCCACGTACAGGGAGGCCATGG | PABPC4 | ENSG00000090621 | -0.24086839744470412 | [1109] | [2561] | -2 | hSpCas9 | negative selection | 2349598 | 39573774 | 39573797 | 1 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCGCCATTGCACTCCAGCCTGGG | PABPC4 | ENSG00000090621 | -0.7836007518198642 | [44,14] | [5,0] | -4 | dCas9-VP64 | positive selection | 2394656 | 39573774 | 39573797 | 1 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCGCCATTGCACTCCAGCCTGGG | PABPC4 | ENSG00000090621 | -1.3426926137865989 | [87,148] | [18,10] | -9 | dCas9-VP64 | positive selection | 2489911 | 39575879 | 39575902 | 1 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CCTGCATTCGGACGTCACCGAGG | PABPC4 | ENSG00000090621 | 0.5907302074475417 | [3,3] | [4,5] | 9 | hSpCas9 | positive selection | 3009338 | 39575849 | 39575872 | 1 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GTACGAAAAGTTCAGCCCCGCGG | PABPC4 | ENSG00000090621 | 0.1269908129846107 | [4,4] | [4,3] | 2 | hSpCas9 | positive selection | 3009339 | 39575879 | 39575902 | 1 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CCTGCATTCGGACGTCACCGAGG | PABPC4 | ENSG00000090621 | 0.23836366501462863 | [3,3] | [4,2] | 4 | hSpCas9 | positive selection | 3077196 | 39575849 | 39575872 | 1 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GTACGAAAAGTTCAGCCCCGCGG | PABPC4 | ENSG00000090621 | 0.23051137353420487 | [4,4] | [3,3] | 4 | hSpCas9 | positive selection | 3077197 | 39563608 | 39563631 | | + | 24336571 | A375 | resistance to PLX after 7 days | CCTCACCTGCAGAGGCTGTATGG | PABPC4 | ENSG00000090621 | 0.22505625222821357 | [20,17] | [22,21] | 6 | hSpCas9 | positive selection | 3133692 | 39563608 | 39563631 | | + | 24336571 | A375 | resistance to PLX after 14 days | CCTCACCTGCAGAGGCTGTATGG | PABPC4 | ENSG00000090621 | -0.04839474141828787 | [17,16] | [7,6] | 0 | hSpCas9 | positive selection | 3191485 | 39563608 | 39563631 | | + | 24336571 | A375 | viability after 7 days | CCTCACCTGCAGAGGCTGTATGG | PABPC4 | ENSG00000090621 | 0.3446791949474804 | [15] | [20,17] | 5 | hSpCas9 | negative selection | 3249278 | 39563608 | 39563631 | | + | 24336571 | A375 | viability after 14 days | CCTCACCTGCAGAGGCTGTATGG | PABPC4 | ENSG00000090621 | 0.22884238579388333 | [15] | [17,16] | 3 | hSpCas9 | negative selection | 3307071 | 39563661 | 39563684 | 1 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | -1.2818325996621964 | [371,371] | [0,0] | -8 | hSpCas9 | positive selection | 3384423 | 39575879 | 39575902 | 1 | - | 26780180 | HT29 | viability (Avana library 4 designs) | CCTGCATTCGGACGTCACCGAGG | PABPC4 | ENSG00000090621 | 0.428778036447085 | [] | [] | 1 | hSpCas9 | negative selection | 3447359 | 39575849 | 39575872 | 1 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GTACGAAAAGTTCAGCCCCGCGG | PABPC4 | ENSG00000090621 | 0.795623736158127 | [] | [] | 3 | hSpCas9 | negative selection | 3447360 | 39575849 | 39575872 | 1 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GTACGAAAAGTTCAGCCCCGCGG | PABPC4 | ENSG00000090621 | 1.72340412041882 | [] | [] | 2 | hSpCas9 | negative selection | 3541126 | 39575879 | 39575902 | 1 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCTGCATTCGGACGTCACCGAGG | PABPC4 | ENSG00000090621 | 4.08500290553527 | [] | [] | 6 | hSpCas9 | negative selection | 3541127 | 39575778 | 39575801 | 1 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GTTGACGTAGGCATAGCCCAGGG | PABPC4 | ENSG00000090621 | -0.0500704299976945 | [] | [] | 0 | hSpCas9 | negative selection | 3541128 | 39575847 | 39575870 | 1 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | 2.21864896281746 | [] | [] | 3 | hSpCas9 | negative selection | 3541129 | 39575849 | 39575872 | 1 | - | 26780180 | A375 | viability (Avana lentiGuide) | GTACGAAAAGTTCAGCCCCGCGG | PABPC4 | ENSG00000090621 | 3.38423831679027 | [] | [] | 3 | hSpCas9 | negative selection | 3649785 | 39575879 | 39575902 | 1 | - | 26780180 | A375 | viability (Avana lentiGuide) | CCTGCATTCGGACGTCACCGAGG | PABPC4 | ENSG00000090621 | -4.20088450828482 | [] | [] | -7 | hSpCas9 | negative selection | 3649786 | 39575778 | 39575801 | 1 | + | 26780180 | A375 | viability (Avana lentiGuide) | GTTGACGTAGGCATAGCCCAGGG | PABPC4 | ENSG00000090621 | 4.2874143491467 | [] | [] | 4 | hSpCas9 | negative selection | 3649787 | 39575847 | 39575870 | 1 | - | 26780180 | A375 | viability (Avana lentiGuide) | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | 4.86873018214199 | [] | [] | 4 | hSpCas9 | negative selection | 3649788 | 39575849 | 39575872 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GTACGAAAAGTTCAGCCCCGCGG | PABPC4 | ENSG00000090621 | 0.10953028907802134 | [5] | [6,5] | 3 | hSpCas9 | positive selection | 3758444 | 39575879 | 39575902 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCTGCATTCGGACGTCACCGAGG | PABPC4 | ENSG00000090621 | 0.2903558924039228 | [4] | [6,4] | 8 | hSpCas9 | positive selection | 3758445 | 39575778 | 39575801 | 1 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GTTGACGTAGGCATAGCCCAGGG | PABPC4 | ENSG00000090621 | 0.11249004315249617 | [6] | [6,6] | 3 | hSpCas9 | positive selection | 3758446 | 39575847 | 39575870 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.05562888535076288 | [3] | [2,4] | -1 | hSpCas9 | positive selection | 3758447 | 39575849 | 39575872 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GTACGAAAAGTTCAGCCCCGCGG | PABPC4 | ENSG00000090621 | -0.06494200805790233 | [6] | [4,5] | -1 | hSpCas9 | positive selection | 3867051 | 39575879 | 39575902 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCTGCATTCGGACGTCACCGAGG | PABPC4 | ENSG00000090621 | -0.13219260715846423 | [5] | [4,3] | -2 | hSpCas9 | positive selection | 3867052 | 39575778 | 39575801 | 1 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GTTGACGTAGGCATAGCCCAGGG | PABPC4 | ENSG00000090621 | -0.04965960762402449 | [6] | [4,5] | 0 | hSpCas9 | positive selection | 3867053 | 39575847 | 39575870 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.5738930765723875 | [5] | [2,2] | -6 | hSpCas9 | positive selection | 3867054 | 39563661 | 39563684 | 1 | + | 26780180 | A375 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.910677808193313 | [] | [] | 4 | hSpCas9 | negative selection | 3977978 | 39563661 | 39563684 | 1 | + | 26780180 | HT29 | viability (GeCKOv2 library) | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.87845196075176 | [] | [] | 4 | hSpCas9 | negative selection | 4085944 | 39563608 | 39563631 | 1 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CCTCACCTGCAGAGGCTGTATGG | PABPC4 | ENSG00000090621 | 0.07509664284397333 | [4] | [2,2] | 2 | hSpCas9 | positive selection | 4158530 | 39563608 | 39563631 | 1 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CCTCACCTGCAGAGGCTGTATGG | PABPC4 | ENSG00000090621 | 1.1373863803803188 | [3] | [1,3,3,4] | 8 | hSpCas9 | positive selection | 4222552 | 39563661 | 39563684 | 1 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.5755123238058666 | [3] | [3,4] | 9 | hSpCas9 | positive selection | 4352840 | 39576557 | 39576580 | 1 | + | 27661255 | K562 | viability | GACCGACGGACGGAGACCGACGG | PABPC4 | ENSG00000090621 | -0.018136136227119515 | [939,947] | [777,715] | 0 | dCas9-KRAB | negative selection | 5499856 | 39576740 | 39576763 | 1 | + | 27661255 | K562 | viability | GCTGCGAAGCCCGAAAGCGGCGG | PABPC4 | ENSG00000090621 | 0.2347139044491624 | [243,412] | [313,298] | 7 | dCas9-KRAB | negative selection | 5499857 | 39576762 | 39576785 | 1 | + | 27661255 | K562 | viability | GAGGCGGCAGCGACCCGGGGCGG | PABPC4 | ENSG00000090621 | -1.5394865221272762 | [734,947] | [247,214] | -9 | dCas9-KRAB | negative selection | 5499858 | 39563661 | 39563684 | 1 | + | 27260156 | BXPC3 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.22264076776808917 | [755] | [768,903,985,1059] | 5 | hSpCas9 | negative selection | 5625300 | 39563661 | 39563684 | 1 | + | 27260156 | A673 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.10408865018884783 | [755] | [1084,885,789,1166] | 2 | hSpCas9 | negative selection | 5746551 | 39563661 | 39563684 | 1 | + | 27260156 | A375 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.07815738696110253 | [755] | [660,1351,878,893] | 1 | hSpCas9 | negative selection | 5867802 | 39563661 | 39563684 | 1 | + | 27260156 | COLO741 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.16983537099124224 | [755] | [1232,1248,808] | 3 | hSpCas9 | negative selection | 5989053 | 39563661 | 39563684 | 1 | + | 27260156 | CAL120 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.07007071445657564 | [755] | [781,1195,953] | 1 | hSpCas9 | negative selection | 6110304 | 39563661 | 39563684 | 1 | + | 27260156 | CADOES1 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.41186132535778075 | [755] | [878,1121,991,741] | 6 | hSpCas9 | negative selection | 6231555 | 39563661 | 39563684 | 1 | + | 27260156 | EWS502 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.4291072794871358 | [755] | [910,1008,1271,1146] | 7 | hSpCas9 | negative selection | 6352806 | 39563661 | 39563684 | 1 | + | 27260156 | EW8 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.08228346822653054 | [755] | [720,659,599,627] | 1 | hSpCas9 | negative selection | 6474057 | 39563661 | 39563684 | 1 | + | 27260156 | CORL105 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.39180097440215733 | [755] | [1088,1118,1040,1373] | 7 | hSpCas9 | negative selection | 6595308 | 39563661 | 39563684 | 1 | + | 27260156 | HS294T | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.2902724566588961 | [755] | [330,447,316,326] | 4 | hSpCas9 | negative selection | 6716559 | 39563661 | 39563684 | 1 | + | 27260156 | HCC44 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.28817804333384356 | [755] | [926,947,1565,826] | 5 | hSpCas9 | negative selection | 6837810 | 39563661 | 39563684 | 1 | + | 27260156 | G402 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.5304743069877913 | [755] | [1034,1909,1140,1233] | 6 | hSpCas9 | negative selection | 6959061 | 39563661 | 39563684 | 1 | + | 27260156 | L33 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | -0.02226211739056927 | [755] | [800,251,495,770] | 0 | hSpCas9 | negative selection | 7080312 | 39563661 | 39563684 | 1 | + | 27260156 | K562 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.5688208228688605 | [755] | [1569,1198,702,607] | 7 | hSpCas9 | negative selection | 7201563 | 39563661 | 39563684 | 1 | + | 27260156 | HT29 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.24524704748324377 | [755] | [1227,1321,813,1023] | 5 | hSpCas9 | negative selection | 7322814 | 39563661 | 39563684 | 1 | + | 27260156 | MHHES1 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.03443168369162375 | [755] | [1026,1145,731,658] | 0 | hSpCas9 | negative selection | 7444065 | 39563661 | 39563684 | 1 | + | 27260156 | MEWO | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.10088134519579228 | [755] | [752,819,700] | 2 | hSpCas9 | negative selection | 7565316 | 39563661 | 39563684 | 1 | + | 27260156 | LNCAPCLONEFGC | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.22186303821786524 | [755] | [745,774,631,1018] | 3 | hSpCas9 | negative selection | 7686567 | 39563661 | 39563684 | 1 | + | 27260156 | PANC0327 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.15807142052175494 | [755] | [731,628,714,934] | 2 | hSpCas9 | negative selection | 7807818 | 39563661 | 39563684 | 1 | + | 27260156 | NCIH2009 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.18912719441731618 | [755] | [1353,1323,959] | 2 | hSpCas9 | negative selection | 7929069 | 39563661 | 39563684 | 1 | + | 27260156 | NCIH1373 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | -0.003809294890972703 | [755] | [1448,376,860,218] | 0 | hSpCas9 | negative selection | 8050320 | 39563661 | 39563684 | 1 | + | 27260156 | PATU8902 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.9311039000891868 | [755] | [2174,2061,1917,1862] | 8 | hSpCas9 | negative selection | 8171571 | 39563661 | 39563684 | 1 | + | 27260156 | PANC1 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.13986101818131969 | [755] | [870,667,723,593] | 2 | hSpCas9 | negative selection | 8292822 | 39563661 | 39563684 | 1 | + | 27260156 | PANC0813 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.0646486826480982 | [755] | [932,906,758,1103] | 1 | hSpCas9 | negative selection | 8414073 | 39563661 | 39563684 | 1 | + | 27260156 | RDES | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.21257363227766368 | [755] | [885,933,1135,1092] | 3 | hSpCas9 | negative selection | 8535324 | 39563661 | 39563684 | 1 | + | 27260156 | PC3 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.22317364305522525 | [755] | [712,866,1310,754] | 5 | hSpCas9 | negative selection | 8656575 | 39563661 | 39563684 | 1 | + | 27260156 | PATU8988T | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.19482604418125926 | [755] | [813,827,769,940] | 3 | hSpCas9 | negative selection | 8777826 | 39563661 | 39563684 | 1 | + | 27260156 | T47D | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.1904210988763444 | [755] | [1012,908,988,1120] | 4 | hSpCas9 | negative selection | 8899077 | 39563661 | 39563684 | 1 | + | 27260156 | SU8686 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.29580355678488046 | [755] | [922,861,841,1076] | 5 | hSpCas9 | negative selection | 9020328 | 39563661 | 39563684 | 1 | + | 27260156 | SKES1 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.1370879028570915 | [755] | [853,919,770,783] | 3 | hSpCas9 | negative selection | 9141579 | 39563661 | 39563684 | 1 | + | 27260156 | TOV112D | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.38969226036098004 | [755] | [745,1482,1156,688] | 7 | hSpCas9 | negative selection | 9262830 | 39563661 | 39563684 | 1 | + | 27260156 | TC71 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.011577302035010839 | [755] | [961,725,762,814] | 0 | hSpCas9 | negative selection | 9384081 | 39563661 | 39563684 | 1 | + | 27260156 | TC32 | viability | ATTTGTAGGGGGCAACAGCCCGG | PABPC4 | ENSG00000090621 | 0.24046175649998647 | [755] | [624,716,1183,918] | 4 | hSpCas9 | negative selection | 9505332 | 39564436 | 39564459 | 1 | + | 27869803 | HPAFII | viability after 27 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.47574865159656693 | [141] | [165,51,NaN] | 4 | hSpCas9 | negative selection | 9534280 | 39564694 | 39564717 | 1 | + | 27869803 | HPAFII | viability after 27 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 1.0959244199985356 | [414] | [569,379,NaN] | 8 | hSpCas9 | negative selection | 9534281 | 39565126 | 39565149 | 1 | + | 27869803 | HPAFII | viability after 27 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 0.8630810214275582 | [209] | [148,243,NaN] | 7 | hSpCas9 | negative selection | 9534282 | 39575824 | 39575847 | 1 | + | 27869803 | HPAFII | viability after 27 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.0029913736917603906 | [519] | [250,290,NaN] | 0 | hSpCas9 | negative selection | 9534283 | 39564436 | 39564459 | 1 | + | 27869803 | HPAFII | viability after 15 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.8168594610603228 | [141] | [467,144,NaN] | 8 | hSpCas9 | negative selection | 9616729 | 39564694 | 39564717 | 1 | + | 27869803 | HPAFII | viability after 15 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.5482671207712567 | [414] | [1007,430,NaN] | 6 | hSpCas9 | negative selection | 9616730 | 39565126 | 39565149 | 1 | + | 27869803 | HPAFII | viability after 15 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | -0.23076362863971717 | [209] | [179,199,NaN] | -3 | hSpCas9 | negative selection | 9616731 | 39575824 | 39575847 | 1 | + | 27869803 | HPAFII | viability after 15 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.138746636172022 | [519] | [855,290,NaN] | -2 | hSpCas9 | negative selection | 9616732 | 39564436 | 39564459 | 1 | + | 27869803 | ASPC1 | viability after 36 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.0809575799945978 | [490] | [149,288,67] | -1 | hSpCas9 | negative selection | 9699178 | 39564694 | 39564717 | 1 | + | 27869803 | ASPC1 | viability after 36 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.3831151861486547 | [1139] | [583,470,505] | 4 | hSpCas9 | negative selection | 9699179 | 39565126 | 39565149 | 1 | + | 27869803 | ASPC1 | viability after 36 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | -0.5667692791983775 | [560] | [50,170,156] | -5 | hSpCas9 | negative selection | 9699180 | 39575824 | 39575847 | 1 | + | 27869803 | ASPC1 | viability after 36 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.4720608634872092 | [1305] | [401,442,182] | -5 | hSpCas9 | negative selection | 9699181 | 39564436 | 39564459 | 1 | + | 27869803 | PATU8988S | viability after 35 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.11498953195785316 | [480] | [126,230,NaN] | -1 | hSpCas9 | negative selection | 9781627 | 39564694 | 39564717 | 1 | + | 27869803 | PATU8988S | viability after 35 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.9276832749496606 | [989] | [958,556,NaN] | 8 | hSpCas9 | negative selection | 9781628 | 39565126 | 39565149 | 1 | + | 27869803 | PATU8988S | viability after 35 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 0.637372681018963 | [527] | [452,207,NaN] | 7 | hSpCas9 | negative selection | 9781629 | 39575824 | 39575847 | 1 | + | 27869803 | PATU8988S | viability after 35 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | 0.03982250682084143 | [875] | [442,281,NaN] | 0 | hSpCas9 | negative selection | 9781630 | 39564436 | 39564459 | 1 | + | 27869803 | PATU8988S | viability after 31 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.47236712906327183 | [480] | [150,121,NaN] | -5 | hSpCas9 | negative selection | 9864076 | 39564694 | 39564717 | 1 | + | 27869803 | PATU8988S | viability after 31 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.45531414234895484 | [989] | [553,524,NaN] | 5 | hSpCas9 | negative selection | 9864077 | 39565126 | 39565149 | 1 | + | 27869803 | PATU8988S | viability after 31 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 0.5597268455270584 | [527] | [352,255,NaN] | 6 | hSpCas9 | negative selection | 9864078 | 39575824 | 39575847 | 1 | + | 27869803 | PATU8988S | viability after 31 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | -0.01345528579206634 | [875] | [426,242,NaN] | 0 | hSpCas9 | negative selection | 9864079 | 39564436 | 39564459 | 1 | + | 27869803 | HPAFII | viability after 35 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | 0.23797062599404217 | [141] | [112,52,NaN] | 1 | hSpCas9 | negative selection | 9946525 | 39564694 | 39564717 | 1 | + | 27869803 | HPAFII | viability after 35 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 1.1211589039723173 | [414] | [448,465,NaN] | 7 | hSpCas9 | negative selection | 9946526 | 39565126 | 39565149 | 1 | + | 27869803 | HPAFII | viability after 35 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 0.9477681278157226 | [209] | [94,328,NaN] | 6 | hSpCas9 | negative selection | 9946527 | 39575824 | 39575847 | 1 | + | 27869803 | HPAFII | viability after 35 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | 0.5276242235640014 | [519] | [291,477,NaN] | 3 | hSpCas9 | negative selection | 9946528 | 39564436 | 39564459 | 1 | + | 27869803 | HPAFII | viability after 31 days | GGTAGTAGGGAGGCCACGAGAGG | PABPC4 | ENSG00000090621 | -0.9988340959940828 | [141] | [25,54,NaN] | -6 | hSpCas9 | negative selection | 10028974 | 39564694 | 39564717 | 1 | + | 27869803 | HPAFII | viability after 31 days | CTCCCACCTTGCTGCCAGCGTGG | PABPC4 | ENSG00000090621 | 0.9248656699392207 | [414] | [445,437,NaN] | 7 | hSpCas9 | negative selection | 10028975 | 39565126 | 39565149 | 1 | + | 27869803 | HPAFII | viability after 31 days | AGTAGCCACCCGCTGCAGGCTGG | PABPC4 | ENSG00000090621 | 0.8238198274529716 | [209] | [65,363,NaN] | 6 | hSpCas9 | negative selection | 10028976 | 39575824 | 39575847 | 1 | + | 27869803 | HPAFII | viability after 31 days | CAGACCCGGATGGACAGCACAGG | PABPC4 | ENSG00000090621 | 0.3265905979710404 | [519] | [342,390,NaN] | 2 | hSpCas9 | negative selection | 10028977 | 39565135 | 39565158 | 1 | - | 28162770 | P31FUJ | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | 0.7057972509214778 | [47] | [91] | 7 | hSpCas9 | negative selection | 10206083 | 39575833 | 39575856 | 1 | + | 28162770 | P31FUJ | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | 0.056704412780606374 | [215] | [263] | 0 | hSpCas9 | negative selection | 10206084 | 39575786 | 39575809 | 1 | + | 28162770 | P31FUJ | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | 0.5985981916098766 | [67] | [120] | 6 | hSpCas9 | negative selection | 10206085 | 39575939 | 39575962 | 1 | - | 28162770 | P31FUJ | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.21290264697667383 | [143] | [145] | -2 | hSpCas9 | negative selection | 10206086 | 39575847 | 39575870 | 1 | - | 28162770 | P31FUJ | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.5000860832495304 | [135] | [112] | -4 | hSpCas9 | negative selection | 10206087 | 39575766 | 39575789 | 1 | + | 28162770 | P31FUJ | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | 2.525896911699109 | [55] | [378] | 9 | hSpCas9 | negative selection | 10206088 | 39565135 | 39565158 | 1 | - | 28162770 | TF1 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | NaN | [NaN] | [31] | 1 | hSpCas9 | negative selection | 10375449 | 39575833 | 39575856 | 1 | + | 28162770 | TF1 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | NaN | [NaN] | [119] | 1 | hSpCas9 | negative selection | 10375450 | 39575786 | 39575809 | 1 | + | 28162770 | TF1 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | NaN | [NaN] | [44] | 1 | hSpCas9 | negative selection | 10375451 | 39575939 | 39575962 | 1 | - | 28162770 | TF1 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | NaN | [NaN] | [54] | 1 | hSpCas9 | negative selection | 10375452 | 39575847 | 39575870 | 1 | - | 28162770 | TF1 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | NaN | [NaN] | [90] | 1 | hSpCas9 | negative selection | 10375453 | 39575766 | 39575789 | 1 | + | 28162770 | TF1 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | NaN | [NaN] | [60] | 1 | hSpCas9 | negative selection | 10375454 | 39565135 | 39565158 | 1 | - | 28162770 | SKM1 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | -1.8220016980220053 | [15] | [7] | -8 | hSpCas9 | negative selection | 10544815 | 39575833 | 39575856 | 1 | + | 28162770 | SKM1 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | -0.3997686973389578 | [49] | [66] | -3 | hSpCas9 | negative selection | 10544816 | 39575786 | 39575809 | 1 | + | 28162770 | SKM1 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | -0.9422959317397175 | [24] | [22] | -6 | hSpCas9 | negative selection | 10544817 | 39575939 | 39575962 | 1 | - | 28162770 | SKM1 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -3.880895387075574 | [24] | [2] | -9 | hSpCas9 | negative selection | 10544818 | 39575847 | 39575870 | 1 | - | 28162770 | SKM1 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.06300979752580038 | [25] | [43] | 0 | hSpCas9 | negative selection | 10544819 | 39575766 | 39575789 | 1 | + | 28162770 | SKM1 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | -1.92153737157292 | [14] | [6] | -8 | hSpCas9 | negative selection | 10544820 | 39565135 | 39565158 | 1 | - | 28162770 | SKM1 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | -1.8220016980220053 | [15] | [7] | -8 | hSpCas9 | negative selection | 10714181 | 39575833 | 39575856 | 1 | + | 28162770 | SKM1 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | -0.3997686973389578 | [49] | [66] | -3 | hSpCas9 | negative selection | 10714182 | 39575786 | 39575809 | 1 | + | 28162770 | SKM1 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | -0.9422959317397175 | [24] | [22] | -6 | hSpCas9 | negative selection | 10714183 | 39575939 | 39575962 | 1 | - | 28162770 | SKM1 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -3.880895387075574 | [24] | [2] | -9 | hSpCas9 | negative selection | 10714184 | 39575847 | 39575870 | 1 | - | 28162770 | SKM1 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.06300979752580038 | [25] | [43] | 0 | hSpCas9 | negative selection | 10714185 | 39575766 | 39575789 | 1 | + | 28162770 | SKM1 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | -1.92153737157292 | [14] | [6] | -8 | hSpCas9 | negative selection | 10714186 | 39565135 | 39565158 | 1 | - | 28162770 | PL21 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | -0.2737915738430923 | [24] | [8] | -2 | hSpCas9 | negative selection | 10883547 | 39575833 | 39575856 | 1 | + | 28162770 | PL21 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | -0.7718460093410833 | [203] | [51] | -5 | hSpCas9 | negative selection | 10883548 | 39575786 | 39575809 | 1 | + | 28162770 | PL21 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | -1.4569726719876714 | [81] | [12] | -7 | hSpCas9 | negative selection | 10883549 | 39575939 | 39575962 | 1 | - | 28162770 | PL21 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.9291434024556464 | [69] | [15] | -6 | hSpCas9 | negative selection | 10883550 | 39575847 | 39575870 | 1 | - | 28162770 | PL21 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -1.4879163791959398 | [115] | [17] | -7 | hSpCas9 | negative selection | 10883551 | 39575766 | 39575789 | 1 | + | 28162770 | PL21 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | -1.64785729206563 | [35] | [4] | -8 | hSpCas9 | negative selection | 10883552 | 39565135 | 39565158 | 1 | - | 28162770 | P31FUJ | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | 0.7057972509214778 | [47] | [91] | 7 | hSpCas9 | negative selection | 11052913 | 39575833 | 39575856 | 1 | + | 28162770 | P31FUJ | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | 0.056704412780606374 | [215] | [263] | 0 | hSpCas9 | negative selection | 11052914 | 39575786 | 39575809 | 1 | + | 28162770 | P31FUJ | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | 0.5985981916098766 | [67] | [120] | 6 | hSpCas9 | negative selection | 11052915 | 39575939 | 39575962 | 1 | - | 28162770 | P31FUJ | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.21290264697667383 | [143] | [145] | -2 | hSpCas9 | negative selection | 11052916 | 39575847 | 39575870 | 1 | - | 28162770 | P31FUJ | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.5000860832495304 | [135] | [112] | -4 | hSpCas9 | negative selection | 11052917 | 39575766 | 39575789 | 1 | + | 28162770 | P31FUJ | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | 2.525896911699109 | [55] | [378] | 9 | hSpCas9 | negative selection | 11052918 | 39565135 | 39565158 | 1 | - | 28162770 | OCIAML5 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | 0.34057850707839865 | [20] | [47] | 3 | hSpCas9 | negative selection | 11222279 | 39575833 | 39575856 | 1 | + | 28162770 | OCIAML5 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | 0.1123095194052815 | [81] | [159] | 0 | hSpCas9 | negative selection | 11222280 | 39575786 | 39575809 | 1 | + | 28162770 | OCIAML5 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | 0.5040772393612785 | [24] | [63] | 4 | hSpCas9 | negative selection | 11222281 | 39575939 | 39575962 | 1 | - | 28162770 | OCIAML5 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.23988260140781636 | [69] | [106] | -2 | hSpCas9 | negative selection | 11222282 | 39575847 | 39575870 | 1 | - | 28162770 | OCIAML5 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -1.6225847247412297 | [57] | [33] | -7 | hSpCas9 | negative selection | 11222283 | 39575766 | 39575789 | 1 | + | 28162770 | OCIAML5 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | -1.4936125999515206 | [38] | [24] | -7 | hSpCas9 | negative selection | 11222284 | 39565135 | 39565158 | 1 | - | 28162770 | EOL1 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | -0.2770860895991163 | [45] | [19] | -2 | hSpCas9 | negative selection | 11391645 | 39575833 | 39575856 | 1 | + | 28162770 | EOL1 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | -0.276320937080046 | [376] | [163] | -2 | hSpCas9 | negative selection | 11391646 | 39575786 | 39575809 | 1 | + | 28162770 | EOL1 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | -1.2061559200740595 | [126] | [28] | -7 | hSpCas9 | negative selection | 11391647 | 39575939 | 39575962 | 1 | - | 28162770 | EOL1 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.8777715605897711 | [142] | [40] | -6 | hSpCas9 | negative selection | 11391648 | 39575847 | 39575870 | 1 | - | 28162770 | EOL1 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.4309328830278544 | [173] | [67] | -3 | hSpCas9 | negative selection | 11391649 | 39575766 | 39575789 | 1 | + | 28162770 | EOL1 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | -0.5900254012592239 | [59] | [20] | -4 | hSpCas9 | negative selection | 11391650 | 39565135 | 39565158 | 1 | - | 28162770 | MOLM13 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | -0.1798088745245403 | [46] | [29] | -1 | hSpCas9 | negative selection | 11561011 | 39575833 | 39575856 | 1 | + | 28162770 | MOLM13 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | 0.22591659123861446 | [271] | [229] | 1 | hSpCas9 | negative selection | 11561012 | 39575786 | 39575809 | 1 | + | 28162770 | MOLM13 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | -1.2651717581657114 | [122] | [36] | -6 | hSpCas9 | negative selection | 11561013 | 39575939 | 39575962 | 1 | - | 28162770 | MOLM13 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.5691048259376229 | [157] | [76] | -3 | hSpCas9 | negative selection | 11561014 | 39575847 | 39575870 | 1 | - | 28162770 | MOLM13 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.2658305531179733 | [147] | [88] | -2 | hSpCas9 | negative selection | 11561015 | 39575766 | 39575789 | 1 | + | 28162770 | MOLM13 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | -1.7020356198977338 | [80] | [17] | -7 | hSpCas9 | negative selection | 11561016 | 39565135 | 39565158 | 1 | - | 28162770 | HEL | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | -3.6051886814432286 | [56] | [2] | -9 | hSpCas9 | negative selection | 11730377 | 39575833 | 39575856 | 1 | + | 28162770 | HEL | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | 0.18705934822416712 | [191] | [139] | 1 | hSpCas9 | negative selection | 11730378 | 39575786 | 39575809 | 1 | + | 28162770 | HEL | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | 0.23938313776914866 | [81] | [61] | 2 | hSpCas9 | negative selection | 11730379 | 39575939 | 39575962 | 1 | - | 28162770 | HEL | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.3378958431327118 | [147] | [74] | -2 | hSpCas9 | negative selection | 11730380 | 39575847 | 39575870 | 1 | - | 28162770 | HEL | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.22686453074396795 | [147] | [80] | -2 | hSpCas9 | negative selection | 11730381 | 39575766 | 39575789 | 1 | + | 28162770 | HEL | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | -3.12279591436262 | [67] | [4] | -9 | hSpCas9 | negative selection | 11730382 | 39565135 | 39565158 | 1 | - | 28162770 | MV411 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | 0.614219881454398 | [37] | [48] | 5 | hSpCas9 | negative selection | 11899743 | 39575833 | 39575856 | 1 | + | 28162770 | MV411 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | -0.21041303203504144 | [227] | [165] | -2 | hSpCas9 | negative selection | 11899744 | 39575786 | 39575809 | 1 | + | 28162770 | MV411 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | -0.9838879953236808 | [53] | [22] | -6 | hSpCas9 | negative selection | 11899745 | 39575939 | 39575962 | 1 | - | 28162770 | MV411 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | 0.016112004676319347 | [107] | [91] | 0 | hSpCas9 | negative selection | 11899746 | 39575847 | 39575870 | 1 | - | 28162770 | MV411 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | 0.3271647432535093 | [87] | [92] | 3 | hSpCas9 | negative selection | 11899747 | 39575766 | 39575789 | 1 | + | 28162770 | MV411 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | 0.14434405781867166 | [57] | [53] | 1 | hSpCas9 | negative selection | 11899748 | 39565135 | 39565158 | 1 | - | 28162770 | MONOMAC1 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | 1.626085390856367 | [25] | [91] | 9 | hSpCas9 | negative selection | 12069109 | 39575833 | 39575856 | 1 | + | 28162770 | MONOMAC1 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | -0.23045984859700389 | [130] | [127] | -2 | hSpCas9 | negative selection | 12069110 | 39575786 | 39575809 | 1 | + | 28162770 | MONOMAC1 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | 0.18998627604969376 | [38] | [50] | 2 | hSpCas9 | negative selection | 12069111 | 39575939 | 39575962 | 1 | - | 28162770 | MONOMAC1 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.2194046600880083 | [64] | [63] | -2 | hSpCas9 | negative selection | 12069112 | 39575847 | 39575870 | 1 | - | 28162770 | MONOMAC1 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -1.0568591890112933 | [48] | [26] | -7 | hSpCas9 | negative selection | 12069113 | 39575766 | 39575789 | 1 | + | 28162770 | MONOMAC1 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | 0.3879256536616025 | [25] | [38] | 4 | hSpCas9 | negative selection | 12069114 | 39565135 | 39565158 | 1 | - | 28162770 | OCIAML2 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | 1.5472920827551013 | [4] | [80] | 9 | hSpCas9 | negative selection | 12238475 | 39575833 | 39575856 | 1 | + | 28162770 | OCIAML2 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | 0.09663067374553591 | [40] | [242] | 0 | hSpCas9 | negative selection | 12238476 | 39575786 | 39575809 | 1 | + | 28162770 | OCIAML2 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | 0.6869114517443186 | [12] | [115] | 6 | hSpCas9 | negative selection | 12238477 | 39575939 | 39575962 | 1 | - | 28162770 | OCIAML2 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.22777330134599771 | [14] | [70] | -2 | hSpCas9 | negative selection | 12238478 | 39575847 | 39575870 | 1 | - | 28162770 | OCIAML2 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | -0.5591664998438185 | [20] | [78] | -4 | hSpCas9 | negative selection | 12238479 | 39575766 | 39575789 | 1 | + | 28162770 | OCIAML2 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | 0.8512982696452012 | [2] | [29] | 8 | hSpCas9 | negative selection | 12238480 | 39565135 | 39565158 | 1 | - | 28162770 | OCIAML3 | viability | AAATCAGTTCCAGCCTGCAGCGG | PABPC4 | ENSG00000090621 | -1.5940076403241632 | [14] | [14] | -8 | hSpCas9 | negative selection | 12407841 | 39575833 | 39575856 | 1 | + | 28162770 | OCIAML3 | viability | ATGGACAGCACAGGCCCCGCGGG | PABPC4 | ENSG00000090621 | -0.6706289219270757 | [57] | [109] | -5 | hSpCas9 | negative selection | 12407842 | 39575786 | 39575809 | 1 | + | 28162770 | OCIAML3 | viability | AGGCATAGCCCAGGGAGCGGCGG | PABPC4 | ENSG00000090621 | -2.468476758240304 | [21] | [11] | -9 | hSpCas9 | negative selection | 12407843 | 39575939 | 39575962 | 1 | - | 28162770 | OCIAML3 | viability | GGGCGGGGAGATGAACGCTGCGG | PABPC4 | ENSG00000090621 | -0.2341116952377802 | [29] | [76] | -2 | hSpCas9 | negative selection | 12407844 | 39575847 | 39575870 | 1 | - | 28162770 | OCIAML3 | viability | ACGAAAAGTTCAGCCCCGCGGGG | PABPC4 | ENSG00000090621 | 0.28793659815412465 | [34] | [128] | 2 | hSpCas9 | negative selection | 12407845 | 39575766 | 39575789 | 1 | + | 28162770 | OCIAML3 | viability | CGGCTGCTGGAAGTTGACGTAGG | PABPC4 | ENSG00000090621 | -3.079434467494405 | [13] | [4] | -9 | hSpCas9 | negative selection | 12407846 |