Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5062
• Symbol:PAK2
• Description:p21 (RAC1) activated kinase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/PAK2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
196806648	196806671	3	-	26472758	Jiyoye	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-0.400179540551731	[6]	[3]	-3	hSpCas9	negative selection	115530
196820504	196820527	3	+	26472758	Jiyoye	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	0.1365277915622044	[75]	[62]	1	hSpCas9	negative selection	115531
196820438	196820461	3	+	26472758	Jiyoye	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	0.6152835768360738	[57]	[66]	4	hSpCas9	negative selection	115532
196803012	196803035	3	+	26472758	Jiyoye	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.30168225265855936	[155]	[144]	2	hSpCas9	negative selection	115533
196803086	196803109	3	-	26472758	Jiyoye	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.17778711921528267	[200]	[133]	-1	hSpCas9	negative selection	115534
196806569	196806592	3	+	26472758	Jiyoye	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	-0.12056225052233255	[172]	[119]	-1	hSpCas9	negative selection	115535
196814478	196814501	3	+	26472758	Jiyoye	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-1.7733968641359472	[67]	[14]	-8	hSpCas9	negative selection	115536
196820405	196820428	3	+	26472758	Jiyoye	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	-0.15717683953999662	[277]	[187]	-1	hSpCas9	negative selection	115537
196782686	196782709	3	-	26472758	Jiyoye	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	1.4071753815058727	[0]	[1]	8	hSpCas9	negative selection	115538
196782761	196782784	3	-	26472758	Jiyoye	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	115539
196806648	196806671	3	-	26472758	KBM7	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-0.37771688264711356	[36,63]	[11,24]	-3	hSpCas9	negative selection	306648
196820504	196820527	3	+	26472758	KBM7	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	0.27843094342241315	[338,373]	[104,294]	3	hSpCas9	negative selection	306649
196820438	196820461	3	+	26472758	KBM7	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-0.5296658494574317	[302,330]	[118,90]	-5	hSpCas9	negative selection	306650
196803012	196803035	3	+	26472758	KBM7	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.09315579399708607	[889,840]	[435,433]	0	hSpCas9	negative selection	306651
196803086	196803109	3	-	26472758	KBM7	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-1.3523360326099656	[1013,921]	[229,131]	-7	hSpCas9	negative selection	306652
196806569	196806592	3	+	26472758	KBM7	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	0.5191969699526231	[851,704]	[614,438]	5	hSpCas9	negative selection	306653
196814478	196814501	3	+	26472758	KBM7	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-1.2866442501620399	[204,255]	[32,55]	-7	hSpCas9	negative selection	306654
196820405	196820428	3	+	26472758	KBM7	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	0.2696527942518736	[1190,1555]	[709,866]	3	hSpCas9	negative selection	306655
196782686	196782709	3	-	26472758	KBM7	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	-0.4626802268132435	[33,100]	[8,37]	-4	hSpCas9	negative selection	306656
196782761	196782784	3	-	26472758	KBM7	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	1.4407469509461444	[41,24]	[53,30]	9	hSpCas9	negative selection	306657
196806648	196806671	3	-	26472758	Raji	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-3.9587056550841733	[66]	[0]	-9	hSpCas9	negative selection	497766
196820504	196820527	3	+	26472758	Raji	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	1.1474609747489348	[141]	[72]	8	hSpCas9	negative selection	497767
196820438	196820461	3	+	26472758	Raji	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	1.438208030749358	[96]	[60]	9	hSpCas9	negative selection	497768
196803012	196803035	3	+	26472758	Raji	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.8558447683776352	[349]	[146]	7	hSpCas9	negative selection	497769
196803086	196803109	3	-	26472758	Raji	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.29820248856067233	[354]	[66]	-2	hSpCas9	negative selection	497770
196806569	196806592	3	+	26472758	Raji	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	1.1943668369682394	[353]	[187]	9	hSpCas9	negative selection	497771
196814478	196814501	3	+	26472758	Raji	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-0.9603610712622348	[217]	[25]	-6	hSpCas9	negative selection	497772
196820405	196820428	3	+	26472758	Raji	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	0.7479807350675747	[584]	[227]	7	hSpCas9	negative selection	497773
196782686	196782709	3	-	26472758	Raji	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	3.0333829539298227	[9]	[18]	9	hSpCas9	negative selection	497774
196782761	196782784	3	-	26472758	Raji	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	1.7381497257078804	[30]	[23]	9	hSpCas9	negative selection	497775
196806648	196806671	3	-	26472758	K562	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-5.8430441135838915	[67]	[0]	-9	hSpCas9	negative selection	688884
196820504	196820527	3	+	26472758	K562	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	-1.4050840252494199	[479]	[152]	-6	hSpCas9	negative selection	688885
196820438	196820461	3	+	26472758	K562	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-0.5153181741584176	[297]	[175]	-3	hSpCas9	negative selection	688886
196803012	196803035	3	+	26472758	K562	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.4834583970194266	[676]	[798]	4	hSpCas9	negative selection	688887
196803086	196803109	3	-	26472758	K562	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-1.1270295030647142	[651]	[251]	-6	hSpCas9	negative selection	688888
196806569	196806592	3	+	26472758	K562	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	0.2927249244827417	[557]	[576]	2	hSpCas9	negative selection	688889
196814478	196814501	3	+	26472758	K562	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-3.2981085067343128	[267]	[22]	-8	hSpCas9	negative selection	688890
196820405	196820428	3	+	26472758	K562	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	-0.175632090651771	[1056]	[789]	-1	hSpCas9	negative selection	688891
196782686	196782709	3	-	26472758	K562	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	0.06258040468063353	[75]	[66]	0	hSpCas9	negative selection	688892
196782761	196782784	3	-	26472758	K562	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	1.4394347100715894	[37]	[86]	9	hSpCas9	negative selection	688893
196803158	196803181	3	-	26627737	DLD1	viability	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-1.2449766943268021	[493]	[52,100,45]	-8	hSpCas9	negative selection	821119
196806661	196806684	3	-	26627737	DLD1	viability	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.7649863594645012	[334]	[203,239,103]	7	hSpCas9	negative selection	821120
196828315	196828338	3	+	26627737	DLD1	viability	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	1.1611377751577447	[689]	[472,436,527]	9	hSpCas9	negative selection	821121
196828322	196828345	3	-	26627737	DLD1	viability	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-0.10133685387585423	[342]	[113,89,95]	-1	hSpCas9	negative selection	821122
196803158	196803181	3	-	26627737	GBM cells	viability after 5 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-0.45656677971270343	[173]	[89,45]	-6	hSpCas9	negative selection	903434
196806661	196806684	3	-	26627737	GBM cells	viability after 5 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.43843340484567456	[171]	[131,117]	6	hSpCas9	negative selection	903435
196828315	196828338	3	+	26627737	GBM cells	viability after 5 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.011725193719715366	[749]	[426,383]	0	hSpCas9	negative selection	903436
196828322	196828345	3	-	26627737	GBM cells	viability after 5 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-0.1069152039165119	[247]	[99,146]	-2	hSpCas9	negative selection	903437
196803158	196803181	3	-	26627737	GBM cells	viability after 13 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-0.45662706716819257	[173]	[70,66]	-5	hSpCas9	negative selection	985749
196806661	196806684	3	-	26627737	GBM cells	viability after 13 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.5774480641101543	[171]	[173,110]	7	hSpCas9	negative selection	985750
196828315	196828338	3	+	26627737	GBM cells	viability after 13 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.013498928968342927	[749]	[407,412]	0	hSpCas9	negative selection	985751
196828322	196828345	3	-	26627737	GBM cells	viability after 13 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-0.05094989928075232	[247]	[114,141]	0	hSpCas9	negative selection	985752
196803158	196803181	3	-	26627737	GBM cells	viability after 21 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-1.047536025668776	[173]	[51,39]	-7	hSpCas9	negative selection	1068064
196806661	196806684	3	-	26627737	GBM cells	viability after 21 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.4923998489004872	[171]	[155,108]	5	hSpCas9	negative selection	1068065
196828315	196828338	3	+	26627737	GBM cells	viability after 21 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.31798185852240235	[749]	[532,484]	3	hSpCas9	negative selection	1068066
196828322	196828345	3	-	26627737	GBM cells	viability after 21 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-0.7655228488774736	[247]	[84,73]	-6	hSpCas9	negative selection	1068067
196803158	196803181	3	-	26627737	RPE1	viability after 9 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-1.0886420035548374	[909]	[143,120]	-7	hSpCas9	negative selection	1150379
196806661	196806684	3	-	26627737	RPE1	viability after 9 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.5764798569758066	[733]	[109,210]	-4	hSpCas9	negative selection	1150380
196828315	196828338	3	+	26627737	RPE1	viability after 9 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	-0.39537127398578553	[2712]	[557,758]	-3	hSpCas9	negative selection	1150381
196828322	196828345	3	-	26627737	RPE1	viability after 9 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-1.5817266542377495	[1194]	[117,133]	-8	hSpCas9	negative selection	1150382
196803158	196803181	3	-	26627737	RPE1	viability after 12 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-1.1642929529539496	[909]	[128,87]	-7	hSpCas9	negative selection	1232694
196806661	196806684	3	-	26627737	RPE1	viability after 12 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.46740563925279294	[733]	[146,137]	-3	hSpCas9	negative selection	1232695
196828315	196828338	3	+	26627737	RPE1	viability after 12 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	-0.1350813003711122	[2712]	[773,546]	-1	hSpCas9	negative selection	1232696
196828322	196828345	3	-	26627737	RPE1	viability after 12 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-1.8667835411005882	[1194]	[139,32]	-8	hSpCas9	negative selection	1232697
196803158	196803181	3	-	26627737	RPE1	viability after 15 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-1.5967408925348257	[909]	[78,90]	-7	hSpCas9	negative selection	1315009
196806661	196806684	3	-	26627737	RPE1	viability after 15 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.6312137070575209	[733]	[130,136]	-4	hSpCas9	negative selection	1315010
196828315	196828338	3	+	26627737	RPE1	viability after 15 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	-0.23248051738150433	[2712]	[780,529]	-1	hSpCas9	negative selection	1315011
196828322	196828345	3	-	26627737	RPE1	viability after 15 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-1.9175949923520172	[1194]	[146,33]	-8	hSpCas9	negative selection	1315012
196803158	196803181	3	-	26627737	RPE1	viability after 18 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-2.704051622130215	[909]	[13,62]	-9	hSpCas9	negative selection	1397324
196806661	196806684	3	-	26627737	RPE1	viability after 18 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.06836636925572281	[733]	[227,185]	0	hSpCas9	negative selection	1397325
196828315	196828338	3	+	26627737	RPE1	viability after 18 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	-0.34338797690110945	[2712]	[724,418]	-2	hSpCas9	negative selection	1397326
196828322	196828345	3	-	26627737	RPE1	viability after 18 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-1.8485852886179877	[1194]	[119,56]	-8	hSpCas9	negative selection	1397327
196803158	196803181	3	-	26627737	HeLa	viability after 8 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	1.878942001517402	[79]	[111,131,135]	9	hSpCas9	negative selection	1479639
196806661	196806684	3	-	26627737	HeLa	viability after 8 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.4149382292572804	[338]	[303,162,149]	4	hSpCas9	negative selection	1479640
196828315	196828338	3	+	26627737	HeLa	viability after 8 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	-0.07086225248792788	[1147]	[669,374,427]	0	hSpCas9	negative selection	1479641
196828322	196828345	3	-	26627737	HeLa	viability after 8 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	0.5829549022226872	[310]	[257,95,261]	5	hSpCas9	negative selection	1479642
196803158	196803181	3	-	26627737	HeLa	viability after 12 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	1.5475199933167163	[79]	[137,78,75]	9	hSpCas9	negative selection	1561954
196806661	196806684	3	-	26627737	HeLa	viability after 12 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.6073307908324717	[338]	[311,195,136]	5	hSpCas9	negative selection	1561955
196828315	196828338	3	+	26627737	HeLa	viability after 12 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	-0.05925540386323602	[1147]	[544,413,413]	0	hSpCas9	negative selection	1561956
196828322	196828345	3	-	26627737	HeLa	viability after 12 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	0.5847083355908378	[310]	[264,148,170]	5	hSpCas9	negative selection	1561957
196803158	196803181	3	-	26627737	HeLa	viability after 15 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	2.1800004361854324	[79]	[196,110,132]	9	hSpCas9	negative selection	1644269
196806661	196806684	3	-	26627737	HeLa	viability after 15 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.5727396359659604	[338]	[269,259,74]	4	hSpCas9	negative selection	1644270
196828315	196828338	3	+	26627737	HeLa	viability after 15 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	-0.3248746827759117	[1147]	[384,266,474]	-3	hSpCas9	negative selection	1644271
196828322	196828345	3	-	26627737	HeLa	viability after 15 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	0.16729150005435728	[310]	[139,138,147]	1	hSpCas9	negative selection	1644272
196803158	196803181	3	-	26627737	HeLa	viability after 18 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	2.1438226588734097	[79]	[124,91,132]	9	hSpCas9	negative selection	1726584
196806661	196806684	3	-	26627737	HeLa	viability after 18 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.5280048639906414	[338]	[169,213,74]	4	hSpCas9	negative selection	1726585
196828315	196828338	3	+	26627737	HeLa	viability after 18 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	-0.3428541777926266	[1147]	[250,218,474]	-3	hSpCas9	negative selection	1726586
196828322	196828345	3	-	26627737	HeLa	viability after 18 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	0.16409577470916722	[310]	[90,117,147]	1	hSpCas9	negative selection	1726587
196803158	196803181	3	-	26627737	HCT116	viability after 6 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	1.6844456382019921	[244]	[10,185]	8	hSpCas9	negative selection	1808899
196806661	196806684	3	-	26627737	HCT116	viability after 6 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.11224736222154752	[336]	[64,52]	0	hSpCas9	negative selection	1808900
196828315	196828338	3	+	26627737	HCT116	viability after 6 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.6319660216451165	[982]	[301,204]	3	hSpCas9	negative selection	1808901
196828322	196828345	3	-	26627737	HCT116	viability after 6 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-0.04491295595303274	[525]	[74,82]	0	hSpCas9	negative selection	1808902
196803158	196803181	3	-	26627737	HCT116	viability after 8 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	2.123596147282748	[43]	[158,59,98]	9	hSpCas9	negative selection	1891214
196806661	196806684	3	-	26627737	HCT116	viability after 8 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.09577517143302261	[339]	[162,209,152]	-1	hSpCas9	negative selection	1891215
196828315	196828338	3	+	26627737	HCT116	viability after 8 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	-0.02649705831718885	[844]	[479,447,443]	0	hSpCas9	negative selection	1891216
196828322	196828345	3	-	26627737	HCT116	viability after 8 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	0.115802771488831	[225]	[131,156,115]	1	hSpCas9	negative selection	1891217
196803158	196803181	3	-	26627737	HCT116	viability after 9 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	1.5376601241198826	[244]	[161,211]	8	hSpCas9	negative selection	1973529
196806661	196806684	3	-	26627737	HCT116	viability after 9 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	1.018106546870739	[336]	[74,266]	7	hSpCas9	negative selection	1973530
196828315	196828338	3	+	26627737	HCT116	viability after 9 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.4945857949628488	[982]	[466,292]	3	hSpCas9	negative selection	1973531
196828322	196828345	3	-	26627737	HCT116	viability after 9 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-1.5603843346473698	[525]	[55,40]	-8	hSpCas9	negative selection	1973532
196803158	196803181	3	-	26627737	HCT116	viability after 12 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	1.6405783702337555	[43]	[76,77,60]	9	hSpCas9	negative selection	2055844
196806661	196806684	3	-	26627737	HCT116	viability after 12 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.26377264322067634	[339]	[195,164,282]	2	hSpCas9	negative selection	2055845
196828315	196828338	3	+	26627737	HCT116	viability after 12 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.27883860406989136	[844]	[567,468,574]	3	hSpCas9	negative selection	2055846
196828322	196828345	3	-	26627737	HCT116	viability after 12 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	0.7194466043680818	[225]	[106,217,269]	6	hSpCas9	negative selection	2055847
196803158	196803181	3	-	26627737	HCT116	viability after 15 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	2.442662390469663	[43]	[158,55,198]	9	hSpCas9	negative selection	2138159
196806661	196806684	3	-	26627737	HCT116	viability after 15 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.17532991094604405	[339]	[219,174,129]	-2	hSpCas9	negative selection	2138160
196828315	196828338	3	+	26627737	HCT116	viability after 15 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.12929830528733288	[844]	[471,566,545]	1	hSpCas9	negative selection	2138161
196828322	196828345	3	-	26627737	HCT116	viability after 15 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	0.4650921938518388	[225]	[121,184,222]	4	hSpCas9	negative selection	2138162
196803158	196803181	3	-	26627737	HCT116	viability after 18 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	2.3664902565994548	[43]	[113,82,134]	9	hSpCas9	negative selection	2220474
196806661	196806684	3	-	26627737	HCT116	viability after 18 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.036986049998948056	[339]	[102,231,139]	0	hSpCas9	negative selection	2220475
196828315	196828338	3	+	26627737	HCT116	viability after 18 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	-0.12288706849303721	[844]	[411,406,300]	-1	hSpCas9	negative selection	2220476
196828322	196828345	3	-	26627737	HCT116	viability after 18 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	0.13222447410322707	[225]	[46,125,188]	1	hSpCas9	negative selection	2220477
196782638	196782661	3	+	24336569	HL60	viability	TTCTGAATCATGTCTGATAACGG	PAK2	ENSG00000180370	0.739445838535109	[226]	[801]	6	hSpCas9	negative selection	2282502
196782646	196782669	3	+	24336569	HL60	viability	CATGTCTGATAACGGAGAACTGG	PAK2	ENSG00000180370	0.024521667813742154	[609]	[1312]	0	hSpCas9	negative selection	2282503
196782686	196782709	3	-	24336569	HL60	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	2.233577608673226	[146]	[1462]	9	hSpCas9	negative selection	2282504
196782761	196782784	3	-	24336569	HL60	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	-0.39195730045397514	[376]	[607]	-3	hSpCas9	negative selection	2282505
196803012	196803035	3	+	24336569	HL60	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.08128799429947797	[1276]	[2858]	0	hSpCas9	negative selection	2282506
196803023	196803046	3	-	24336569	HL60	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.4936506141359128	[244]	[729]	4	hSpCas9	negative selection	2282507
196803051	196803074	3	-	24336569	HL60	viability	CTCTAGTTTGGTGATATTGGAGG	PAK2	ENSG00000180370	-0.09720274807104673	[552]	[1093]	-1	hSpCas9	negative selection	2282508
196803086	196803109	3	-	24336569	HL60	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	0.8547458871051319	[866]	[3317]	7	hSpCas9	negative selection	2282509
196803106	196803129	3	-	24336569	HL60	viability	TGTTGGAGTCGTAGAACTTTAGG	PAK2	ENSG00000180370	-0.20624055345282477	[868]	[1593]	-2	hSpCas9	negative selection	2282510
196803143	196803166	3	+	24336569	HL60	viability	TATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	-1.4493364918290599	[661]	[512]	-8	hSpCas9	negative selection	2282511
196782638	196782661	3	+	24336569	KBM7	viability	TTCTGAATCATGTCTGATAACGG	PAK2	ENSG00000180370	0.9725056374672779	[320]	[1717]	8	hSpCas9	negative selection	2349679
196782646	196782669	3	+	24336569	KBM7	viability	CATGTCTGATAACGGAGAACTGG	PAK2	ENSG00000180370	0.8441869278282275	[550]	[2697]	7	hSpCas9	negative selection	2349680
196782686	196782709	3	-	24336569	KBM7	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	-0.5368465346459701	[124]	[234]	-4	hSpCas9	negative selection	2349681
196782761	196782784	3	-	24336569	KBM7	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	-0.14230957041435144	[330]	[817]	-1	hSpCas9	negative selection	2349682
196803012	196803035	3	+	24336569	KBM7	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.09471797031290863	[1374]	[3511]	-1	hSpCas9	negative selection	2349683
196803023	196803046	3	-	24336569	KBM7	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	-0.7719299537031004	[297]	[475]	-5	hSpCas9	negative selection	2349684
196803051	196803074	3	-	24336569	KBM7	viability	CTCTAGTTTGGTGATATTGGAGG	PAK2	ENSG00000180370	0.31723618054419644	[353]	[1202]	3	hSpCas9	negative selection	2349685
196803086	196803109	3	-	24336569	KBM7	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-1.542527600604145	[941]	[881]	-7	hSpCas9	negative selection	2349686
196803106	196803129	3	-	24336569	KBM7	viability	TGTTGGAGTCGTAGAACTTTAGG	PAK2	ENSG00000180370	-0.27532538904659726	[618]	[1394]	-2	hSpCas9	negative selection	2349687
196803143	196803166	3	+	24336569	KBM7	viability	TATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	-0.0010634657968704442	[254]	[694]	0	hSpCas9	negative selection	2349688
196820921	196820944	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCTTGAACCTGGGAGGTGGCGG	PAK2	ENSG00000180370	-1.7942305092270365	[61,1]	[0,1]	-8	dCas9-VP64	positive selection	2412426
196781063	196781086	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCATCGTGCCCAG	PAK2	ENSG00000180370	-2.3680687732448105	[443,16]	[15,1]	-9	dCas9-VP64	positive selection	2440272
196826244	196826267	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCTGCCTCCCGG	PAK2	ENSG00000180370	3.3241346106645673	[178,128]	[9,695]	8	dCas9-VP64	positive selection	2462090
196761205	196761228	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGGATTTGGCAGGGTCATGGG	PAK2	ENSG00000180370	-0.790516927701566	[268,882]	[32,116]	-4	dCas9-VP64	positive selection	2462319
196811238	196811261	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGGGAGGGGAGGGAGGGAAGG	PAK2	ENSG00000180370	0.11629316738718565	[0,20]	[0,3]	0	dCas9-VP64	positive selection	2470710
196820921	196820944	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCTTGAACCTGGGAGGTGGCGG	PAK2	ENSG00000180370	1.9777309334960365	[57,27]	[33,74]	8	dCas9-VP64	positive selection	2507681
196781063	196781086	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCATCGTGCCCAG	PAK2	ENSG00000180370	0.42142368151358683	[69,54]	[32,21]	3	dCas9-VP64	positive selection	2535527
196826244	196826267	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCTGCCTCCCGG	PAK2	ENSG00000180370	-0.24751078726835885	[128,142]	[21,50]	-2	dCas9-VP64	positive selection	2557345
196761205	196761228	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGGATTTGGCAGGGTCATGGG	PAK2	ENSG00000180370	-1.1226036564357147	[772,320]	[76,86]	-9	dCas9-VP64	positive selection	2557574
196811238	196811261	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGGGAGGGGAGGGAGGGAAGG	PAK2	ENSG00000180370	0.17673792060021398	[4,31]	[0,10]	1	dCas9-VP64	positive selection	2565965
196782638	196782661	3	+	27013184	SW480	treatment with recombinant TRAIL	TTCTGAATCATGTCTGATAACGG	PAK2	ENSG00000180370	1.9724018501858054	[244,129]	[463,129]	8	hSpCas9	positive selection	2965256
196782646	196782669	3	+	27013184	SW480	treatment with recombinant TRAIL	CATGTCTGATAACGGAGAACTGG	PAK2	ENSG00000180370	-1.319864865180449	[298,692]	[78,87]	-6	hSpCas9	positive selection	2965257
196806569	196806592	3	+	27013184	SW480	treatment with recombinant TRAIL	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	2.109717942698232	[299,320]	[817,232]	8	hSpCas9	positive selection	2965258
196806570	196806593	3	+	27013184	SW480	treatment with recombinant TRAIL	TCAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	-1.9959290224661452	[159,211]	[23,13]	-7	hSpCas9	positive selection	2965259
196807771	196807794	3	+	27013184	SW480	treatment with recombinant TRAIL	TGTCTCCACAGATTTACACACGG	PAK2	ENSG00000180370	-3.41840989874052	[200,130]	[5,7]	-9	hSpCas9	positive selection	2965260
196807803	196807826	3	+	27013184	SW480	treatment with recombinant TRAIL	GACCCTGTTCCTGCACCAGTTGG	PAK2	ENSG00000180370	-1.3570081506155907	[318,565]	[49,104]	-6	hSpCas9	positive selection	2965261
196812237	196812260	3	+	27013184	SW480	treatment with recombinant TRAIL	CACTGCTACTGACGTTGCACTGG	PAK2	ENSG00000180370	2.4223299918452	[182,232]	[241,808]	8	hSpCas9	positive selection	2965268
196812238	196812261	3	+	27013184	SW480	treatment with recombinant TRAIL	ACTGCTACTGACGTTGCACTGGG	PAK2	ENSG00000180370	0.5855134106835036	[26,90]	[4,80]	3	hSpCas9	positive selection	2965272
196812243	196812266	3	+	27013184	SW480	treatment with recombinant TRAIL	TACTGACGTTGCACTGGGACAGG	PAK2	ENSG00000180370	-1.9280582674582265	[186,402]	[26,39]	-7	hSpCas9	positive selection	2965273
196812246	196812269	3	+	27013184	SW480	treatment with recombinant TRAIL	TGACGTTGCACTGGGACAGGAGG	PAK2	ENSG00000180370	0.8025818383856282	[26,47]	[3,60]	4	hSpCas9	positive selection	2965274
196812717	196812740	3	+	27013184	SW480	treatment with recombinant TRAIL	TTCAATCCTGTTTTCATTATAGG	PAK2	ENSG00000180370	-0.46877430165243306	[25,40]	[8,11]	-2	hSpCas9	positive selection	2965275
196806651	196806674	3	-	27013184	SW480	treatment with recombinant TRAIL	TCCGGTCGCGGGGCAATAACGGG	PAK2	ENSG00000180370	0.7310464119637634	[308,416]	[289,208]	3	hSpCas9	positive selection	2965276
196812783	196812806	3	+	27013184	SW480	treatment with recombinant TRAIL	ACTGATCATTAACGAGATTCTGG	PAK2	ENSG00000180370	-0.08767376783943118	[227,227]	[92,91]	0	hSpCas9	positive selection	2965277
196806652	196806675	3	-	27013184	SW480	treatment with recombinant TRAIL	ATCCGGTCGCGGGGCAATAACGG	PAK2	ENSG00000180370	-0.478390716274967	[885,804]	[392,77]	-2	hSpCas9	positive selection	2965278
196806662	196806685	3	-	27013184	SW480	treatment with recombinant TRAIL	ATTTCGTATGATCCGGTCGCGGG	PAK2	ENSG00000180370	0.3179494217671437	[762,695]	[282,551]	1	hSpCas9	positive selection	2965279
196806663	196806686	3	-	27013184	SW480	treatment with recombinant TRAIL	GATTTCGTATGATCCGGTCGCGG	PAK2	ENSG00000180370	-0.5436539788647002	[402,289]	[75,143]	-2	hSpCas9	positive selection	2965280
196806669	196806692	3	-	27013184	SW480	treatment with recombinant TRAIL	CTCACTGATTTCGTATGATCCGG	PAK2	ENSG00000180370	-0.20954094651799593	[385,372]	[133,152]	-1	hSpCas9	positive selection	2965281
196807776	196807799	3	-	27013184	SW480	treatment with recombinant TRAIL	ACAGACCGTGTGTAAATCTGTGG	PAK2	ENSG00000180370	1.82902083670281	[95,247]	[299,186]	7	hSpCas9	positive selection	2965282
196807806	196807829	3	-	27013184	SW480	treatment with recombinant TRAIL	TCACCAACTGGTGCAGGAACAGG	PAK2	ENSG00000180370	-0.15506920400846458	[173,130]	[25,107]	0	hSpCas9	positive selection	2965286
196807812	196807835	3	-	27013184	SW480	treatment with recombinant TRAIL	TGTGAATCACCAACTGGTGCAGG	PAK2	ENSG00000180370	1.8647355262309546	[8,25]	[41,3]	8	hSpCas9	positive selection	2965287
196807818	196807841	3	-	27013184	SW480	treatment with recombinant TRAIL	TCAACATGTGAATCACCAACTGG	PAK2	ENSG00000180370	0.12448968059327958	[293,259]	[45,251]	0	hSpCas9	positive selection	2965288
196828338	196828361	3	-	27013184	SW480	treatment with recombinant TRAIL	TGTCAAGCTAGATAACGGTTTGG	PAK2	ENSG00000180370	-3.465695976253968	[78,182]	[6,1]	-9	hSpCas9	positive selection	2965289
196828343	196828366	3	-	27013184	SW480	treatment with recombinant TRAIL	AGTGGTGTCAAGCTAGATAACGG	PAK2	ENSG00000180370	-3.1447788161684116	[543,650]	[37,15]	-9	hSpCas9	positive selection	2965293
196812211	196812234	3	-	27013184	SW480	treatment with recombinant TRAIL	ACTGTACCAGAAGCCCTAGAGGG	PAK2	ENSG00000180370	0.06338779585373996	[196,183]	[41,148]	0	hSpCas9	positive selection	2965294
196812212	196812235	3	-	27013184	SW480	treatment with recombinant TRAIL	AACTGTACCAGAAGCCCTAGAGG	PAK2	ENSG00000180370	-2.079269438473838	[47,73]	[8,1]	-7	hSpCas9	positive selection	2965295
196812723	196812746	3	-	27013184	SW480	treatment with recombinant TRAIL	TAGCAACCTATAATGAAAACAGG	PAK2	ENSG00000180370	-2.360359204484924	[31,13]	[1,1]	-8	hSpCas9	positive selection	2965296
196812772	196812795	3	-	27013184	SW480	treatment with recombinant TRAIL	TTAATGATCAGTTCCTTCTTTGG	PAK2	ENSG00000180370	-0.5429102691260956	[154,247]	[10,125]	-2	hSpCas9	positive selection	2965297
196782680	196782703	3	-	27013184	SW480	treatment with recombinant TRAIL	CTCATTCGCACAGGAGGTGCTGG	PAK2	ENSG00000180370	2.123937136409805	[1,1]	[4,1]	8	hSpCas9	positive selection	2965298
196782686	196782709	3	-	27013184	SW480	treatment with recombinant TRAIL	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	0.0447682533140471	[196,534]	[128,194]	0	hSpCas9	positive selection	2965299
196782689	196782712	3	-	27013184	SW480	treatment with recombinant TRAIL	ATGGTGCTGCTCATTCGCACAGG	PAK2	ENSG00000180370	-1.3920964460657976	[258,414]	[12,112]	-6	hSpCas9	positive selection	2965300
196801931	196801954	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAAAAAGAAAGAAAAGGAACGG	PAK2	ENSG00000180370	0.4324075284310292	[3,3]	[3,3]	8	hSpCas9	positive selection	3009468
196803158	196803181	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	0.06676487566237271	[4,4]	[4,3]	1	hSpCas9	positive selection	3009469
196807818	196807841	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAACATGTGAATCACCAACTGG	PAK2	ENSG00000180370	-0.1906767124022548	[3,3]	[3,1]	-3	hSpCas9	positive selection	3009470
196806661	196806684	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.46474232055458053	[2,2]	[3,3]	8	hSpCas9	positive selection	3009471
196801931	196801954	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAAAAAGAAAGAAAAGGAACGG	PAK2	ENSG00000180370	-0.2562440926391334	[3,3]	[3,0]	-4	hSpCas9	positive selection	3077326
196803158	196803181	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	0.014201482941399057	[4,4]	[5,1]	0	hSpCas9	positive selection	3077327
196807818	196807841	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAACATGTGAATCACCAACTGG	PAK2	ENSG00000180370	-0.13285084779522519	[3,3]	[4,0]	-2	hSpCas9	positive selection	3077328
196806661	196806684	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.6790068676218524	[2,2]	[1,0]	-8	hSpCas9	positive selection	3077329
196803086	196803109		-	24336571	A375	resistance to PLX after 7 days	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	0.2452559254810869	[11,12]	[13,15]	7	hSpCas9	positive selection	3133806
196801968	196801991		-	24336571	A375	resistance to PLX after 7 days	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.4091374688387177	[4,3]	[6,4]	8	hSpCas9	positive selection	3133807
196803012	196803035		+	24336571	A375	resistance to PLX after 7 days	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.37124062887415743	[3,3]	[4,3]	8	hSpCas9	positive selection	3133808
196803143	196803166		+	24336571	A375	resistance to PLX after 7 days	TATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	0.6310724069958855	[20,20]	[34,29]	9	hSpCas9	positive selection	3133809
196801977	196802000		+	24336571	A375	resistance to PLX after 7 days	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.19029497496782488	[7,7]	[7,9]	6	hSpCas9	positive selection	3133811
196803086	196803109		-	24336571	A375	resistance to PLX after 14 days	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	0.3830850113139578	[14,8]	[6,6]	4	hSpCas9	positive selection	3191599
196801968	196801991		-	24336571	A375	resistance to PLX after 14 days	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.4038574601270206	[4,4]	[2,2]	4	hSpCas9	positive selection	3191600
196803012	196803035		+	24336571	A375	resistance to PLX after 14 days	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	1.1740306499237576	[1,2]	[2,1]	8	hSpCas9	positive selection	3191601
196803143	196803166		+	24336571	A375	resistance to PLX after 14 days	TATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	1.9129357379712695	[15,17]	[30,29]	9	hSpCas9	positive selection	3191602
196801977	196802000		+	24336571	A375	resistance to PLX after 14 days	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.07560287302498281	[5,9]	[3,2]	0	hSpCas9	positive selection	3191604
196803086	196803109		-	24336571	A375	viability after 7 days	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.6569003394780446	[20]	[11,12]	-7	hSpCas9	negative selection	3249392
196801968	196801991		-	24336571	A375	viability after 7 days	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.7950428671060954	[8]	[4,3]	-8	hSpCas9	negative selection	3249393
196803012	196803035		+	24336571	A375	viability after 7 days	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.05017974492543664	[3]	[3,3]	0	hSpCas9	negative selection	3249394
196803143	196803166		+	24336571	A375	viability after 7 days	TATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	-0.4084194112874391	[29]	[20,20]	-5	hSpCas9	negative selection	3249395
196801977	196802000		+	24336571	A375	viability after 7 days	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.7767602765104434	[4]	[7,7]	9	hSpCas9	negative selection	3249397
196803086	196803109		-	24336571	A375	viability after 14 days	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.7084006235147833	[20]	[14,8]	-7	hSpCas9	negative selection	3307185
196801968	196801991		-	24336571	A375	viability after 14 days	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.6228435201622822	[8]	[4,4]	-6	hSpCas9	negative selection	3307186
196803012	196803035		+	24336571	A375	viability after 14 days	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.5469813162358861	[3]	[1,2]	-6	hSpCas9	negative selection	3307187
196803143	196803166		+	24336571	A375	viability after 14 days	TATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	-0.6776727496284508	[29]	[15,17]	-7	hSpCas9	negative selection	3307188
196801977	196802000		+	24336571	A375	viability after 14 days	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.7966524327733489	[4]	[5,9]	8	hSpCas9	negative selection	3307190
196801968	196801991	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.3148117061065953	[122,122]	[0,0]	1	hSpCas9	positive selection	3384515
196805366	196805389	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	1.7337642553888224	[45,45]	[0,0]	7	hSpCas9	positive selection	3384516
196805351	196805374	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	-1.470594243117364	[423,423]	[0,0]	-8	hSpCas9	positive selection	3384517
196801930	196801953	3	+	26780180	HT29	viability (Avana library 4 designs)	GTAAAAAGAAAGAAAAGGAACGG	PAK2	ENSG00000180370	4.015643872025	[]	[]	9	hSpCas9	negative selection	3447505
196803158	196803181	3	-	26780180	HT29	viability (Avana library 4 designs)	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-1.03243656495006	[]	[]	-9	hSpCas9	negative selection	3447506
196807818	196807841	3	-	26780180	HT29	viability (Avana library 4 designs)	TCAACATGTGAATCACCAACTGG	PAK2	ENSG00000180370	0.84050791062028	[]	[]	3	hSpCas9	negative selection	3447507
196806661	196806684	3	-	26780180	HT29	viability (Avana library 4 designs)	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.904543169532175	[]	[]	3	hSpCas9	negative selection	3447508
196803158	196803181	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-1.57425248289959	[]	[]	-2	hSpCas9	negative selection	3541343
196807818	196807841	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAACATGTGAATCACCAACTGG	PAK2	ENSG00000180370	-2.53795563516647	[]	[]	-3	hSpCas9	negative selection	3541344
196806661	196806684	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	3.83492822293635	[]	[]	6	hSpCas9	negative selection	3541345
196801930	196801953	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAAAAAGAAAGAAAAGGAACGG	PAK2	ENSG00000180370	-22.1258542445104	[]	[]	-9	hSpCas9	negative selection	3541346
196810586	196810609	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGGAACTATCGTGAGCATAGG	PAK2	ENSG00000180370	-0.313093631459407	[]	[]	0	hSpCas9	negative selection	3541347
196806663	196806686	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATTTCGTATGATCCGGTCGCGG	PAK2	ENSG00000180370	3.11655855576562	[]	[]	5	hSpCas9	negative selection	3541348
196803158	196803181	3	-	26780180	A375	viability (Avana lentiGuide)	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	0.688423477102841	[]	[]	0	hSpCas9	negative selection	3650002
196807818	196807841	3	-	26780180	A375	viability (Avana lentiGuide)	TCAACATGTGAATCACCAACTGG	PAK2	ENSG00000180370	0.25928316889369	[]	[]	0	hSpCas9	negative selection	3650003
196806661	196806684	3	-	26780180	A375	viability (Avana lentiGuide)	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	5.9412944019611	[]	[]	5	hSpCas9	negative selection	3650004
196801930	196801953	3	+	26780180	A375	viability (Avana lentiGuide)	GTAAAAAGAAAGAAAAGGAACGG	PAK2	ENSG00000180370	5.79219576987703	[]	[]	5	hSpCas9	negative selection	3650005
196810586	196810609	3	+	26780180	A375	viability (Avana lentiGuide)	CTAGGAACTATCGTGAGCATAGG	PAK2	ENSG00000180370	13.5876734860147	[]	[]	7	hSpCas9	negative selection	3650006
196806663	196806686	3	-	26780180	A375	viability (Avana lentiGuide)	GATTTCGTATGATCCGGTCGCGG	PAK2	ENSG00000180370	4.91622142992137	[]	[]	4	hSpCas9	negative selection	3650007
196803158	196803181	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	0.14248660350492615	[5]	[5,6]	4	hSpCas9	positive selection	3758661
196807818	196807841	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAACATGTGAATCACCAACTGG	PAK2	ENSG00000180370	-0.06421262060117863	[5]	[5,3]	-1	hSpCas9	positive selection	3758662
196806661	196806684	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.12966883906758261	[4]	[5,4]	3	hSpCas9	positive selection	3758663
196801930	196801953	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAAAAAGAAAGAAAAGGAACGG	PAK2	ENSG00000180370	-1.749684301161377	[9]	[2,1]	-9	hSpCas9	positive selection	3758664
196810586	196810609	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGGAACTATCGTGAGCATAGG	PAK2	ENSG00000180370	0.40744920968000015	[5]	[7,7]	9	hSpCas9	positive selection	3758665
196806663	196806686	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTTCGTATGATCCGGTCGCGG	PAK2	ENSG00000180370	0.3623897728142947	[5]	[7,7]	9	hSpCas9	positive selection	3758666
196803158	196803181	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	0.1998710214130286	[5]	[4,6]	5	hSpCas9	positive selection	3867268
196807818	196807841	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAACATGTGAATCACCAACTGG	PAK2	ENSG00000180370	0.15862889512771258	[5]	[6,4]	4	hSpCas9	positive selection	3867269
196806661	196806684	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.45545304967201844	[4]	[1,3]	-5	hSpCas9	positive selection	3867270
196801930	196801953	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAAAAAGAAAGAAAAGGAACGG	PAK2	ENSG00000180370	-0.25539189133975837	[4]	[1,4]	-3	hSpCas9	positive selection	3867271
196810586	196810609	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGGAACTATCGTGAGCATAGG	PAK2	ENSG00000180370	0.18276748131411857	[6]	[5,6]	4	hSpCas9	positive selection	3867272
196806663	196806686	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTTCGTATGATCCGGTCGCGG	PAK2	ENSG00000180370	0.2309222836970016	[5]	[4,6]	6	hSpCas9	positive selection	3867273
196803023	196803046	3	-	26780180	A375	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	2.61294142411489	[]	[]	9	hSpCas9	negative selection	3978165
196801968	196801991	3	-	26780180	A375	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.812877423812927	[]	[]	3	hSpCas9	negative selection	3978166
196805366	196805389	3	-	26780180	A375	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.832243595435871	[]	[]	3	hSpCas9	negative selection	3978167
196805351	196805374	3	+	26780180	A375	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.225079430685571	[]	[]	0	hSpCas9	negative selection	3978168
196803012	196803035	3	+	26780180	A375	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	1.68476994631559	[]	[]	9	hSpCas9	negative selection	3978169
196801977	196802000	3	+	26780180	A375	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	1.22462986783893	[]	[]	6	hSpCas9	negative selection	3978170
196803023	196803046	3	-	26780180	HT29	viability (GeCKOv2 library)	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	2.28726131397719	[]	[]	9	hSpCas9	negative selection	4086131
196801968	196801991	3	-	26780180	HT29	viability (GeCKOv2 library)	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.308659127252053	[]	[]	0	hSpCas9	negative selection	4086132
196805366	196805389	3	-	26780180	HT29	viability (GeCKOv2 library)	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.437819292339527	[]	[]	1	hSpCas9	negative selection	4086133
196805351	196805374	3	+	26780180	HT29	viability (GeCKOv2 library)	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	-0.639874932179801	[]	[]	-9	hSpCas9	negative selection	4086134
196803012	196803035	3	+	26780180	HT29	viability (GeCKOv2 library)	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.968787684188655	[]	[]	4	hSpCas9	negative selection	4086135
196801977	196802000	3	+	26780180	HT29	viability (GeCKOv2 library)	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.0461801724857501	[]	[]	0	hSpCas9	negative selection	4086136
196803086	196803109	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	0.03484325244525746	[3]	[2,2]	0	hSpCas9	positive selection	4158653
196801968	196801991	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.1562341170037319	[2]	[0,1]	-4	hSpCas9	positive selection	4158654
196803012	196803035	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.2144892834162918	[2]	[0,1]	-5	hSpCas9	positive selection	4158655
196803143	196803166	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	0.27657764359262504	[4]	[3,4]	7	hSpCas9	positive selection	4158656
196801977	196802000	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.09492010179704737	[3]	[2,1]	-2	hSpCas9	positive selection	4158658
196803086	196803109	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.13273274446832822	[3]	[3,2,0,0]	-2	hSpCas9	positive selection	4222675
196801968	196801991	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.9709817512414349	[3]	[3,0,0,3]	6	hSpCas9	positive selection	4222676
196803012	196803035	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.4436255301352193	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4222677
196803143	196803166	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	1.0997351908855193	[4]	[3,2,4,3]	8	hSpCas9	positive selection	4222678
196801977	196802000	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.24427367895268196	[5]	[2,1,3,0]	-4	hSpCas9	positive selection	4222680
196803023	196803046	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	-0.5536175685680677	[4]	[2,1]	-8	hSpCas9	positive selection	4288692
196803012	196803035	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.012727932950094724	[3]	[2,1]	0	hSpCas9	positive selection	4288693
196801977	196802000	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.00035692609268944686	[4]	[4,2]	0	hSpCas9	positive selection	4288694
196801968	196801991	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.37389320863598763	[2]	[1,0]	-7	hSpCas9	positive selection	4352945
196805366	196805389	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.3331252033494264	[1]	[2,1]	6	hSpCas9	positive selection	4352946
196805351	196805374	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.3660343524900655	[3]	[4,3]	7	hSpCas9	positive selection	4352947
196818051	196818073	3	+	27760321	OCIAML3	viability	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	1.7709995682116415	[465,385]	[993,1311]	9	hSpCas9	negative selection	4425399
196803013	196803035	3	+	27760321	OCIAML3	viability	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	1.4402369743791157	[338,250]	[616,624]	9	hSpCas9	negative selection	4425400
196803144	196803166	3	+	27760321	OCIAML3	viability	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	0.5864729900089747	[572,496]	[617,637]	7	hSpCas9	negative selection	4425401
196806571	196806593	3	+	27760321	OCIAML3	viability	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	1.3763238453768665	[306,270]	[530,656]	9	hSpCas9	negative selection	4425402
196806661	196806683	3	-	27760321	OCIAML3	viability	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.2856286210785297	[1190,1019]	[539,924]	-3	hSpCas9	negative selection	4425403
196818051	196818073	3	+	27760321	OCIAML2	viability	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	0.6685540122979601	[465,385]	[474,637]	8	hSpCas9	negative selection	4508862
196803013	196803035	3	+	27760321	OCIAML2	viability	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.27539415454215166	[338,250]	[249,333]	3	hSpCas9	negative selection	4508863
196803144	196803166	3	+	27760321	OCIAML2	viability	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	-0.3751849018711893	[572,496]	[293,383]	-4	hSpCas9	negative selection	4508864
196806571	196806593	3	+	27760321	OCIAML2	viability	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	0.28655912917928433	[306,270]	[253,324]	4	hSpCas9	negative selection	4508865
196806661	196806683	3	-	27760321	OCIAML2	viability	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.8774958785869892	[1190,1019]	[442,540]	-7	hSpCas9	negative selection	4508866
196818051	196818073	3	+	27760321	MV411	viability	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	-0.32193164317030476	[465,385]	[101,406]	-2	hSpCas9	negative selection	4592325
196803013	196803035	3	+	27760321	MV411	viability	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-1.1856453794513788	[338,250]	[103,55]	-6	hSpCas9	negative selection	4592326
196803144	196803166	3	+	27760321	MV411	viability	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	0.527341441114046	[572,496]	[435,614]	4	hSpCas9	negative selection	4592327
196806571	196806593	3	+	27760321	MV411	viability	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	-0.2471388117285952	[306,270]	[151,172]	-2	hSpCas9	negative selection	4592328
196806661	196806683	3	-	27760321	MV411	viability	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.40323042324229164	[1190,1019]	[1454,220]	3	hSpCas9	negative selection	4592329
196818051	196818073	3	+	27760321	HL60	viability	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	0.10327025601064369	[465,385]	[393,348]	1	hSpCas9	negative selection	4675788
196803013	196803035	3	+	27760321	HL60	viability	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.27941317750667405	[338,250]	[155,239]	-3	hSpCas9	negative selection	4675789
196803144	196803166	3	+	27760321	HL60	viability	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	0.26250496394379913	[572,496]	[552,490]	3	hSpCas9	negative selection	4675790
196806571	196806593	3	+	27760321	HL60	viability	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	0.48496727145457397	[306,270]	[289,371]	6	hSpCas9	negative selection	4675791
196806661	196806683	3	-	27760321	HL60	viability	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.5690620761792116	[1190,1019]	[551,664]	-6	hSpCas9	negative selection	4675792
196818051	196818073	3	+	27760321	HT1080	viability	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	-5.1461357321295855	[385,300]	[0,6]	-8	hSpCas9	negative selection	4759251
196803013	196803035	3	+	27760321	HT1080	viability	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-3.8379442107811266	[250,195]	[10,0]	-8	hSpCas9	negative selection	4759252
196803144	196803166	3	+	27760321	HT1080	viability	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	-7.461741823277593	[496,387]	[0,0]	-9	hSpCas9	negative selection	4759253
196806571	196806593	3	+	27760321	HT1080	viability	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	1.166197720745406	[270,211]	[319,101]	6	hSpCas9	negative selection	4759254
196806661	196806683	3	-	27760321	HT1080	viability	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-6.093774584029095	[1019,795]	[0,9]	-9	hSpCas9	negative selection	4759255
196818051	196818073	3	+	27760321	HT29	viability after 7 days	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	-0.07868770555755579	[385,300]	[519,347,400]	-1	hSpCas9	negative selection	4842714
196803013	196803035	3	+	27760321	HT29	viability after 7 days	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.31659427068254464	[250,195]	[341,279,445]	5	hSpCas9	negative selection	4842715
196803144	196803166	3	+	27760321	HT29	viability after 7 days	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	-0.12934958120114626	[496,387]	[624,440,508]	-2	hSpCas9	negative selection	4842716
196806571	196806593	3	+	27760321	HT29	viability after 7 days	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	0.4883069115360789	[270,211]	[559,264,496]	7	hSpCas9	negative selection	4842717
196806661	196806683	3	-	27760321	HT29	viability after 7 days	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.7877509047419323	[1019,795]	[1172,486,445]	-8	hSpCas9	negative selection	4842718
196818051	196818073	3	+	27760321	HT29	viability after 25 days	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	0.32625061993575566	[385,300]	[364,623,494]	3	hSpCas9	negative selection	4926177
196803013	196803035	3	+	27760321	HT29	viability after 25 days	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.44226468882115283	[250,195]	[258,484,296]	5	hSpCas9	negative selection	4926178
196803144	196803166	3	+	27760321	HT29	viability after 25 days	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	0.05094321161181853	[496,387]	[583,545,426]	0	hSpCas9	negative selection	4926179
196806571	196806593	3	+	27760321	HT29	viability after 25 days	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	0.8225972450755878	[270,211]	[545,461,447]	8	hSpCas9	negative selection	4926180
196806661	196806683	3	-	27760321	HT29	viability after 25 days	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.5460588290901087	[1019,795]	[724,634,776]	-5	hSpCas9	negative selection	4926181
196818051	196818073	3	+	27760321	HT29	viability after 22 days	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	0.5126475507831584	[385,300]	[543,494,661]	5	hSpCas9	negative selection	5009640
196803013	196803035	3	+	27760321	HT29	viability after 22 days	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.24077615868693752	[250,195]	[138,520,259]	2	hSpCas9	negative selection	5009641
196803144	196803166	3	+	27760321	HT29	viability after 22 days	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	0.18194369908973962	[496,387]	[478,754,508]	1	hSpCas9	negative selection	5009642
196806571	196806593	3	+	27760321	HT29	viability after 22 days	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	0.8490621511552494	[270,211]	[495,520,491]	8	hSpCas9	negative selection	5009643
196806661	196806683	3	-	27760321	HT29	viability after 22 days	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.604247489017108	[1019,795]	[827,627,610]	-5	hSpCas9	negative selection	5009644
196818051	196818073	3	+	27760321	HT29	viability after 19 days	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	0.7286886386063096	[385,300]	[622,767,561]	7	hSpCas9	negative selection	5093103
196803013	196803035	3	+	27760321	HT29	viability after 19 days	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.6192102052209818	[250,195]	[500,616,82]	6	hSpCas9	negative selection	5093104
196803144	196803166	3	+	27760321	HT29	viability after 19 days	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	0.3592921651870257	[496,387]	[959,699,331]	3	hSpCas9	negative selection	5093105
196806571	196806593	3	+	27760321	HT29	viability after 19 days	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	1.1953587025301664	[270,211]	[493,465,911]	9	hSpCas9	negative selection	5093106
196806661	196806683	3	-	27760321	HT29	viability after 19 days	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.3619618769582189	[1019,795]	[750,655,1002]	-3	hSpCas9	negative selection	5093107
196818051	196818073	3	+	27760321	HT29	viability after 16 days	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	0.4702916749681681	[385,300]	[448,501,638]	5	hSpCas9	negative selection	5176566
196803013	196803035	3	+	27760321	HT29	viability after 16 days	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.1963185174707775	[250,195]	[208,292,349]	2	hSpCas9	negative selection	5176567
196803144	196803166	3	+	27760321	HT29	viability after 16 days	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	0.14560336821110453	[496,387]	[675,470,509]	1	hSpCas9	negative selection	5176568
196806571	196806593	3	+	27760321	HT29	viability after 16 days	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	0.5149781453097975	[270,211]	[403,235,523]	6	hSpCas9	negative selection	5176569
196806661	196806683	3	-	27760321	HT29	viability after 16 days	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.5321192143371801	[1019,795]	[740,474,900]	-5	hSpCas9	negative selection	5176570
196818051	196818073	3	+	27760321	HT29	viability after 13 days	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	0.26291910754228465	[385,300]	[377,483,566]	3	hSpCas9	negative selection	5260029
196803013	196803035	3	+	27760321	HT29	viability after 13 days	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.7068252161499002	[250,195]	[359,405,498]	8	hSpCas9	negative selection	5260030
196803144	196803166	3	+	27760321	HT29	viability after 13 days	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	-0.34666909406985286	[496,387]	[320,601,294]	-4	hSpCas9	negative selection	5260031
196806571	196806593	3	+	27760321	HT29	viability after 13 days	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	0.2610858411776928	[270,211]	[309,286,405]	3	hSpCas9	negative selection	5260032
196806661	196806683	3	-	27760321	HT29	viability after 13 days	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-0.5478972517097588	[1019,795]	[755,712,693]	-6	hSpCas9	negative selection	5260033
196818051	196818073	3	+	27760321	HT29	viability after 10 days	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	0.3124833321539766	[385,300]	[382,626,588]	4	hSpCas9	negative selection	5343492
196803013	196803035	3	+	27760321	HT29	viability after 10 days	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.3385817188100119	[250,195]	[199,489,371]	4	hSpCas9	negative selection	5343493
196803144	196803166	3	+	27760321	HT29	viability after 10 days	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	0.14711971396116547	[496,387]	[663,621,550]	2	hSpCas9	negative selection	5343494
196806571	196806593	3	+	27760321	HT29	viability after 10 days	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	0.5800477141437371	[270,211]	[366,560,427]	7	hSpCas9	negative selection	5343495
196806661	196806683	3	-	27760321	HT29	viability after 10 days	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	-1.070985161841881	[1019,795]	[517,753,356]	-8	hSpCas9	negative selection	5343496
196818051	196818073	3	+	27760321	MOLM13	viability	GTTCAGTGTTTACAGGCATTGG	PAK2	ENSG00000180370	1.310125839375655	[465,385]	[1146,121]	8	hSpCas9	negative selection	5426955
196803013	196803035	3	+	27760321	MOLM13	viability	TTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.012830475228853166	[338,250]	[301,50]	0	hSpCas9	negative selection	5426956
196803144	196803166	3	+	27760321	MOLM13	viability	ATCTGAGCTTTACTCCTCCTGG	PAK2	ENSG00000180370	-0.5787558872303998	[572,496]	[260,150]	-4	hSpCas9	negative selection	5426957
196806571	196806593	3	+	27760321	MOLM13	viability	CAATGCAGCTGAATGCCAAGGG	PAK2	ENSG00000180370	0.9488735097259169	[306,270]	[331,298]	6	hSpCas9	negative selection	5426958
196806661	196806683	3	-	27760321	MOLM13	viability	TTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.0509254147470144	[1190,1019]	[621,662]	0	hSpCas9	negative selection	5426959
196739915	196739938	3	-	27661255	K562	viability	GCAATGGCGACGGCCCGGGCCGG	PAK2	ENSG00000180370	-0.04095858452475232	[576,520]	[466,392]	-2	dCas9-KRAB	negative selection	5499991
196739960	196739983	3	-	27661255	K562	viability	GCGGAGTCCTGCGCACGCCAGGG	PAK2	ENSG00000180370	0.1269786803208652	[562,824]	[705,511]	4	dCas9-KRAB	negative selection	5499992
196739982	196740005	3	-	27661255	K562	viability	GCTACCGCTAGGCCCAGCGGCGG	PAK2	ENSG00000180370	-0.4619299120881537	[499,427]	[271,267]	-7	dCas9-KRAB	negative selection	5499993
196739985	196740008	3	-	27661255	K562	viability	GCTGCTACCGCTAGGCCCAGCGG	PAK2	ENSG00000180370	0.17446737494293094	[610,592]	[495,582]	6	dCas9-KRAB	negative selection	5499994
196740283	196740306	3	-	27661255	K562	viability	GGCTCCCAGCACGCAGGTGGCGG	PAK2	ENSG00000180370	0.10221296447862915	[317,323]	[333,224]	3	dCas9-KRAB	negative selection	5499995
196740455	196740478	3	-	27661255	K562	viability	GGGGAGGGAAGACCGAGAGTCGG	PAK2	ENSG00000180370	0.11259805023302139	[789,1062]	[884,719]	4	dCas9-KRAB	negative selection	5499996
196803023	196803046	3	-	27260156	BXPC3	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.3269312847276209	[1169]	[1471,1434,1516,1740]	7	hSpCas9	negative selection	5561152
196803012	196803035	3	+	27260156	BXPC3	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.25499754223920995	[466]	[533,584,495,733]	5	hSpCas9	negative selection	5561153
196801977	196802000	3	+	27260156	BXPC3	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.25022721307975604	[1338]	[1504,1449,1822,1937]	5	hSpCas9	negative selection	5561154
196801968	196801991	3	-	27260156	BXPC3	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.09997441740381874	[261]	[268,248,391,265]	2	hSpCas9	negative selection	5625405
196805366	196805389	3	-	27260156	BXPC3	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.1291987413711848	[139]	[103,126,122,190]	-3	hSpCas9	negative selection	5625406
196805351	196805374	3	+	27260156	BXPC3	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.3239178244715497	[843]	[1004,1133,970,1335]	7	hSpCas9	negative selection	5625407
196803023	196803046	3	-	27260156	A673	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.2542029034321638	[1169]	[1823,1697,1427,1772]	6	hSpCas9	negative selection	5682403
196803012	196803035	3	+	27260156	A673	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.2047702572843261	[466]	[480,480,431,554]	-5	hSpCas9	negative selection	5682404
196801977	196802000	3	+	27260156	A673	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.0136898526740592	[1338]	[1713,1558,1425,1689]	0	hSpCas9	negative selection	5682405
196801968	196801991	3	-	27260156	A673	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.23276398696099698	[261]	[281,292,194,303]	-5	hSpCas9	negative selection	5746656
196805366	196805389	3	-	27260156	A673	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.05119786537982618	[139]	[174,129,220,170]	1	hSpCas9	negative selection	5746657
196805351	196805374	3	+	27260156	A673	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.19694129343155908	[843]	[1146,1150,987,1369]	5	hSpCas9	negative selection	5746658
196803023	196803046	3	-	27260156	A375	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.5588947370353794	[1169]	[2051,2028,2099,1881]	7	hSpCas9	negative selection	5803654
196803012	196803035	3	+	27260156	A375	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.52539641365661	[466]	[447,329,368,362]	-6	hSpCas9	negative selection	5803655
196801977	196802000	3	+	27260156	A375	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.33724277354308185	[1338]	[1334,1241,1149,1222]	-5	hSpCas9	negative selection	5803656
196801968	196801991	3	-	27260156	A375	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.23765953827249087	[261]	[304,235,351,153]	-3	hSpCas9	negative selection	5867907
196805366	196805389	3	-	27260156	A375	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.054543830326702514	[139]	[247,150,120,157]	0	hSpCas9	negative selection	5867908
196805351	196805374	3	+	27260156	A375	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.24325246808346002	[843]	[1089,1389,1108,1110]	3	hSpCas9	negative selection	5867909
196803023	196803046	3	-	27260156	COLO741	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.12446858226643198	[1169]	[1816,1541,1547]	2	hSpCas9	negative selection	5924905
196803012	196803035	3	+	27260156	COLO741	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.8453712028960754	[466]	[326,389,281]	-9	hSpCas9	negative selection	5924906
196801977	196802000	3	+	27260156	COLO741	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.00623594731702104	[1338]	[1548,1843,1700]	0	hSpCas9	negative selection	5924907
196801968	196801991	3	-	27260156	COLO741	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.2357706088346061	[261]	[295,311,247]	-5	hSpCas9	negative selection	5989158
196805366	196805389	3	-	27260156	COLO741	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.06478260004972669	[139]	[250,106,161]	-1	hSpCas9	negative selection	5989159
196805351	196805374	3	+	27260156	COLO741	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.4137486278949378	[843]	[1666,1172,1481]	8	hSpCas9	negative selection	5989160
196803023	196803046	3	-	27260156	CAL120	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.4539755785523172	[1169]	[2070,1941,1980]	6	hSpCas9	negative selection	6046156
196803012	196803035	3	+	27260156	CAL120	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.36826566368950064	[466]	[419,313,608]	-5	hSpCas9	negative selection	6046157
196801977	196802000	3	+	27260156	CAL120	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.18277193262275504	[1338]	[2445,1613,1699]	2	hSpCas9	negative selection	6046158
196801968	196801991	3	-	27260156	CAL120	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.3163691320681521	[261]	[412,237,158]	-4	hSpCas9	negative selection	6110409
196805366	196805389	3	-	27260156	CAL120	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.02968321205988822	[139]	[107,139,252]	0	hSpCas9	negative selection	6110410
196805351	196805374	3	+	27260156	CAL120	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.5716186867405595	[843]	[1702,1416,1582]	8	hSpCas9	negative selection	6110411
196803023	196803046	3	-	27260156	CADOES1	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.22201338017025551	[1169]	[1214,1102,1247,1519]	4	hSpCas9	negative selection	6167407
196803012	196803035	3	+	27260156	CADOES1	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.3732161055044502	[466]	[392,301,313,331]	-6	hSpCas9	negative selection	6167408
196801977	196802000	3	+	27260156	CADOES1	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.1970164136028112	[1338]	[1152,917,1008,1271]	-3	hSpCas9	negative selection	6167409
196801968	196801991	3	-	27260156	CADOES1	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.08254929272320888	[261]	[254,238,207,217]	-1	hSpCas9	negative selection	6231660
196805366	196805389	3	-	27260156	CADOES1	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.07266537409260865	[139]	[107,130,191,115]	1	hSpCas9	negative selection	6231661
196805351	196805374	3	+	27260156	CADOES1	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.4227670141687987	[843]	[1035,1010,1107,1053]	7	hSpCas9	negative selection	6231662
196803023	196803046	3	-	27260156	EWS502	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.20371716382055594	[1169]	[1388,1537,1286,1491]	3	hSpCas9	negative selection	6288658
196803012	196803035	3	+	27260156	EWS502	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.3861675487020961	[466]	[280,279,434,544]	-6	hSpCas9	negative selection	6288659
196801977	196802000	3	+	27260156	EWS502	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.05979857346248152	[1338]	[954,1581,1560,1383]	-1	hSpCas9	negative selection	6288660
196801968	196801991	3	-	27260156	EWS502	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.23497041966619636	[261]	[116,232,319,291]	-4	hSpCas9	negative selection	6352911
196805366	196805389	3	-	27260156	EWS502	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.0442685224171786	[139]	[74,120,233,195]	0	hSpCas9	negative selection	6352912
196805351	196805374	3	+	27260156	EWS502	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.2663990017810003	[843]	[1147,803,1270,1078]	5	hSpCas9	negative selection	6352913
196803023	196803046	3	-	27260156	EW8	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.2516365395955078	[1169]	[1151,1072,992,1318]	4	hSpCas9	negative selection	6409909
196803012	196803035	3	+	27260156	EW8	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.05088383732222569	[466]	[545,393,244,315]	-1	hSpCas9	negative selection	6409910
196801977	196802000	3	+	27260156	EW8	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.14217124795973302	[1338]	[1209,1247,1043,1311]	2	hSpCas9	negative selection	6409911
196801968	196801991	3	-	27260156	EW8	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.23858288583026444	[261]	[196,289,181,337]	4	hSpCas9	negative selection	6474162
196805366	196805389	3	-	27260156	EW8	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.1587522042352436	[139]	[145,54,58,157]	-3	hSpCas9	negative selection	6474163
196805351	196805374	3	+	27260156	EW8	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.313700539119532	[843]	[966,905,631,942]	6	hSpCas9	negative selection	6474164
196803023	196803046	3	-	27260156	CORL105	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.3612299128679026	[1169]	[1639,1883,1843,1675]	6	hSpCas9	negative selection	6531160
196803012	196803035	3	+	27260156	CORL105	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.13859869739222433	[466]	[550,512,507,417]	-3	hSpCas9	negative selection	6531161
196801977	196802000	3	+	27260156	CORL105	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.14231842230858116	[1338]	[1517,1373,1506,1299]	-3	hSpCas9	negative selection	6531162
196801968	196801991	3	-	27260156	CORL105	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.13743192125151793	[261]	[227,260,374,264]	-3	hSpCas9	negative selection	6595413
196805366	196805389	3	-	27260156	CORL105	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.30597932295235264	[139]	[257,224,213,116]	6	hSpCas9	negative selection	6595414
196805351	196805374	3	+	27260156	CORL105	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.10177865684803544	[843]	[1105,876,1376,935]	2	hSpCas9	negative selection	6595415
196803023	196803046	3	-	27260156	HS294T	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.5528979027831606	[1169]	[637,845,553,599]	7	hSpCas9	negative selection	6652411
196803012	196803035	3	+	27260156	HS294T	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.5633313798731765	[466]	[100,133,117,139]	-7	hSpCas9	negative selection	6652412
196801977	196802000	3	+	27260156	HS294T	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.05227936477717754	[1338]	[424,466,491,643]	0	hSpCas9	negative selection	6652413
196801968	196801991	3	-	27260156	HS294T	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.017752795533699794	[261]	[56,60,143,163]	0	hSpCas9	negative selection	6716664
196805366	196805389	3	-	27260156	HS294T	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.8287540234603128	[139]	[28,16,32,45]	-8	hSpCas9	negative selection	6716665
196805351	196805374	3	+	27260156	HS294T	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.14118365900380592	[843]	[571,252,247,345]	2	hSpCas9	negative selection	6716666
196803023	196803046	3	-	27260156	HCC44	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	-0.028037197372753786	[1169]	[1513,1199,1431,1097]	0	hSpCas9	negative selection	6773662
196803012	196803035	3	+	27260156	HCC44	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-1.6599722132087524	[466]	[113,147,147,248]	-9	hSpCas9	negative selection	6773663
196801977	196802000	3	+	27260156	HCC44	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.7526691471473065	[1338]	[808,1216,830,672]	-8	hSpCas9	negative selection	6773664
196801968	196801991	3	-	27260156	HCC44	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-1.1517141821832177	[261]	[145,91,196,115]	-9	hSpCas9	negative selection	6837915
196805366	196805389	3	-	27260156	HCC44	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-1.1546459694155624	[139]	[52,42,192,19]	-9	hSpCas9	negative selection	6837916
196805351	196805374	3	+	27260156	HCC44	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	-0.010198551401631062	[843]	[1034,729,1166,928]	0	hSpCas9	negative selection	6837917
196803023	196803046	3	-	27260156	G402	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.4854110385797288	[1169]	[1975,2118,2010,1889]	6	hSpCas9	negative selection	6894913
196803012	196803035	3	+	27260156	G402	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-1.156313082211324	[466]	[148,306,101,441]	-8	hSpCas9	negative selection	6894914
196801977	196802000	3	+	27260156	G402	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.44443581680464117	[1338]	[1694,1198,1064,923]	-5	hSpCas9	negative selection	6894915
196801968	196801991	3	-	27260156	G402	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.4952606308250654	[261]	[293,242,373,835]	6	hSpCas9	negative selection	6959166
196805366	196805389	3	-	27260156	G402	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.8677613605106437	[139]	[206,459,361,214]	9	hSpCas9	negative selection	6959167
196805351	196805374	3	+	27260156	G402	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.27426636466421606	[843]	[1139,1649,1111,1090]	3	hSpCas9	negative selection	6959168
196803023	196803046	3	-	27260156	L33	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.27392374737887093	[1169]	[1380,699,835,1240]	6	hSpCas9	negative selection	7016164
196803012	196803035	3	+	27260156	L33	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.1903899842989202	[466]	[426,219,366,585]	4	hSpCas9	negative selection	7016165
196801977	196802000	3	+	27260156	L33	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.49769688025113257	[1338]	[1811,842,1121,1908]	8	hSpCas9	negative selection	7016166
196801968	196801991	3	-	27260156	L33	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.015349279428808593	[261]	[304,130,125,232]	0	hSpCas9	negative selection	7080417
196805366	196805389	3	-	27260156	L33	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.2616850661785175	[139]	[142,104,71,157]	5	hSpCas9	negative selection	7080418
196805351	196805374	3	+	27260156	L33	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.005823858285645689	[843]	[888,348,557,760]	0	hSpCas9	negative selection	7080419
196803023	196803046	3	-	27260156	K562	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.7260111053649441	[1169]	[1636,1810,1953,1485]	8	hSpCas9	negative selection	7137415
196803012	196803035	3	+	27260156	K562	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.7158557552383535	[466]	[252,201,282,265]	-7	hSpCas9	negative selection	7137416
196801977	196802000	3	+	27260156	K562	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.7775653379319468	[1338]	[892,846,415,643]	-7	hSpCas9	negative selection	7137417
196801968	196801991	3	-	27260156	K562	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.6723641668979692	[261]	[112,222,108,139]	-7	hSpCas9	negative selection	7201668
196805366	196805389	3	-	27260156	K562	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.3940260202371466	[139]	[74,250,181,143]	5	hSpCas9	negative selection	7201669
196805351	196805374	3	+	27260156	K562	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.9714151708979619	[843]	[2037,1524,1360,1043]	9	hSpCas9	negative selection	7201670
196803023	196803046	3	-	27260156	HT29	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.2785863543702003	[1169]	[2090,1626,1859,1373]	5	hSpCas9	negative selection	7258666
196803012	196803035	3	+	27260156	HT29	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.17092357882882916	[466]	[585,394,665,378]	-3	hSpCas9	negative selection	7258667
196801977	196802000	3	+	27260156	HT29	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.014549682005809972	[1338]	[1642,1726,1526,1555]	0	hSpCas9	negative selection	7258668
196801968	196801991	3	-	27260156	HT29	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.20128250621613186	[261]	[294,328,202,283]	-4	hSpCas9	negative selection	7322919
196805366	196805389	3	-	27260156	HT29	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.2846460486156299	[139]	[233,204,249,147]	5	hSpCas9	negative selection	7322920
196805351	196805374	3	+	27260156	HT29	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.41689348541204607	[843]	[1698,1135,1294,1346]	7	hSpCas9	negative selection	7322921
196803023	196803046	3	-	27260156	MHHES1	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.2753194229111293	[1169]	[1562,1924,1339,1551]	5	hSpCas9	negative selection	7379917
196803012	196803035	3	+	27260156	MHHES1	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.30011617351126246	[466]	[569,477,325,361]	-5	hSpCas9	negative selection	7379918
196801977	196802000	3	+	27260156	MHHES1	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.12546193609772316	[1338]	[1832,2000,1440,1385]	2	hSpCas9	negative selection	7379919
196801968	196801991	3	-	27260156	MHHES1	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.23506988982614674	[261]	[375,222,296,139]	-4	hSpCas9	negative selection	7444170
196805366	196805389	3	-	27260156	MHHES1	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.8578543571264552	[139]	[109,54,110,72]	-9	hSpCas9	negative selection	7444171
196805351	196805374	3	+	27260156	MHHES1	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	-0.06767498901809732	[843]	[1168,754,1067,684]	-1	hSpCas9	negative selection	7444172
196803023	196803046	3	-	27260156	MEWO	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.24693317612565768	[1169]	[1454,1256,1214]	5	hSpCas9	negative selection	7501168
196803012	196803035	3	+	27260156	MEWO	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.5505867305598791	[466]	[334,283,282]	-8	hSpCas9	negative selection	7501169
196801977	196802000	3	+	27260156	MEWO	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.11755743350853409	[1338]	[1462,1366,1266]	2	hSpCas9	negative selection	7501170
196801968	196801991	3	-	27260156	MEWO	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.10806944468821267	[261]	[369,196,142]	-2	hSpCas9	negative selection	7565421
196805366	196805389	3	-	27260156	MEWO	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.8484763040322965	[139]	[75,39,102]	-9	hSpCas9	negative selection	7565422
196805351	196805374	3	+	27260156	MEWO	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.10611024732140861	[843]	[922,770,869]	2	hSpCas9	negative selection	7565423
196803023	196803046	3	-	27260156	LNCAPCLONEFGC	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.32215883325346684	[1169]	[1252,1290,1689,1122]	5	hSpCas9	negative selection	7622419
196803012	196803035	3	+	27260156	LNCAPCLONEFGC	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-1.0309600453861973	[466]	[208,203,158,248]	-9	hSpCas9	negative selection	7622420
196801977	196802000	3	+	27260156	LNCAPCLONEFGC	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.594076446299139	[1338]	[764,780,925,761]	-7	hSpCas9	negative selection	7622421
196801968	196801991	3	-	27260156	LNCAPCLONEFGC	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.6229391207428123	[261]	[110,104,285,137]	-7	hSpCas9	negative selection	7686672
196805366	196805389	3	-	27260156	LNCAPCLONEFGC	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.6633161626133499	[139]	[47,59,199,31]	-7	hSpCas9	negative selection	7686673
196805351	196805374	3	+	27260156	LNCAPCLONEFGC	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.3979222186581066	[843]	[973,988,1184,908]	6	hSpCas9	negative selection	7686674
196803023	196803046	3	-	27260156	PANC0327	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.38722127410693896	[1169]	[1436,1651,1090,1224]	6	hSpCas9	negative selection	7743670
196803012	196803035	3	+	27260156	PANC0327	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-1.0677153315984385	[466]	[155,214,230,183]	-8	hSpCas9	negative selection	7743671
196801977	196802000	3	+	27260156	PANC0327	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.4434832245303777	[1338]	[560,896,1033,977]	-6	hSpCas9	negative selection	7743672
196801968	196801991	3	-	27260156	PANC0327	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.26580949977478296	[261]	[490,73,252,344]	4	hSpCas9	negative selection	7807923
196805366	196805389	3	-	27260156	PANC0327	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-1.1110148548304082	[139]	[74,39,64,53]	-8	hSpCas9	negative selection	7807924
196805351	196805374	3	+	27260156	PANC0327	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	-0.07935389155101502	[843]	[697,517,773,871]	-1	hSpCas9	negative selection	7807925
196803023	196803046	3	-	27260156	NCIH2009	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.476787443529181	[1169]	[2858,1901,2181]	6	hSpCas9	negative selection	7864921
196803012	196803035	3	+	27260156	NCIH2009	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.7553270351964111	[466]	[574,286,335]	-7	hSpCas9	negative selection	7864922
196801977	196802000	3	+	27260156	NCIH2009	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.16588128243597366	[1338]	[2075,1759,1242]	-2	hSpCas9	negative selection	7864923
196801968	196801991	3	-	27260156	NCIH2009	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.2759555079879952	[261]	[343,340,228]	-4	hSpCas9	negative selection	7929174
196805366	196805389	3	-	27260156	NCIH2009	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.6106569112923692	[139]	[100,167,108]	-6	hSpCas9	negative selection	7929175
196805351	196805374	3	+	27260156	NCIH2009	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	-0.028068738206561528	[843]	[1334,922,1248]	0	hSpCas9	negative selection	7929176
196803023	196803046	3	-	27260156	NCIH1373	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.7424116990739811	[1169]	[2317,2153,2054,595]	7	hSpCas9	negative selection	7986172
196803012	196803035	3	+	27260156	NCIH1373	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-1.6574515391803448	[466]	[108,149,199,51]	-9	hSpCas9	negative selection	7986173
196801977	196802000	3	+	27260156	NCIH1373	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.06690012670051049	[1338]	[1705,1184,1711,306]	0	hSpCas9	negative selection	7986174
196801968	196801991	3	-	27260156	NCIH1373	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.3519535329617157	[261]	[369,267,231,172]	3	hSpCas9	negative selection	8050425
196805366	196805389	3	-	27260156	NCIH1373	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.9010722099318283	[139]	[308,244,193,115]	8	hSpCas9	negative selection	8050426
196805351	196805374	3	+	27260156	NCIH1373	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.1762599087299308	[843]	[1283,1000,720,348]	1	hSpCas9	negative selection	8050427
196803023	196803046	3	-	27260156	PATU8902	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.4886661365130467	[1169]	[3174,2742,1782,1445]	5	hSpCas9	negative selection	8107423
196803012	196803035	3	+	27260156	PATU8902	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-2.1190031976800694	[466]	[252,170,40,160]	-9	hSpCas9	negative selection	8107424
196801977	196802000	3	+	27260156	PATU8902	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-1.1563097702280722	[1338]	[844,617,668,1306]	-7	hSpCas9	negative selection	8107425
196801968	196801991	3	-	27260156	PATU8902	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.8799658278646585	[261]	[192,124,46,501]	-7	hSpCas9	negative selection	8171676
196805366	196805389	3	-	27260156	PATU8902	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.6282689135119388	[139]	[82,88,141,193]	-6	hSpCas9	negative selection	8171677
196805351	196805374	3	+	27260156	PATU8902	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.04718149002705918	[843]	[755,1393,1393,1270]	0	hSpCas9	negative selection	8171678
196803023	196803046	3	-	27260156	PANC1	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.17597709272909334	[1169]	[1014,1417,1021,1127]	2	hSpCas9	negative selection	8228674
196803012	196803035	3	+	27260156	PANC1	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-1.2580214553872393	[466]	[150,289,124,132]	-9	hSpCas9	negative selection	8228675
196801977	196802000	3	+	27260156	PANC1	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.6393478979355185	[1338]	[707,1123,583,622]	-7	hSpCas9	negative selection	8228676
196801968	196801991	3	-	27260156	PANC1	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.7262534885512897	[261]	[143,172,122,112]	-8	hSpCas9	negative selection	8292927
196805366	196805389	3	-	27260156	PANC1	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-1.7932177393016322	[139]	[60,31,29,16]	-9	hSpCas9	negative selection	8292928
196805351	196805374	3	+	27260156	PANC1	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.2668753449667087	[843]	[896,1066,959,630]	4	hSpCas9	negative selection	8292929
196803023	196803046	3	-	27260156	PANC0813	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.4581132635868641	[1169]	[2178,1953,1672,1774]	7	hSpCas9	negative selection	8349925
196803012	196803035	3	+	27260156	PANC0813	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.328864930963997	[466]	[482,496,367,403]	-5	hSpCas9	negative selection	8349926
196801977	196802000	3	+	27260156	PANC0813	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.2681058874525186	[1338]	[1340,1290,1314,1279]	-4	hSpCas9	negative selection	8349927
196801968	196801991	3	-	27260156	PANC0813	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.30272383499332145	[261]	[274,190,298,235]	-5	hSpCas9	negative selection	8414178
196805366	196805389	3	-	27260156	PANC0813	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.0033227916506373134	[139]	[156,218,164,116]	0	hSpCas9	negative selection	8414179
196805351	196805374	3	+	27260156	PANC0813	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.02501827067994078	[843]	[1128,1173,937,813]	0	hSpCas9	negative selection	8414180
196803023	196803046	3	-	27260156	RDES	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.3133310876327291	[1169]	[1339,1528,1748,2186]	5	hSpCas9	negative selection	8471176
196803012	196803035	3	+	27260156	RDES	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.4266545222592574	[466]	[248,382,446,570]	-6	hSpCas9	negative selection	8471177
196801977	196802000	3	+	27260156	RDES	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.15542354752666498	[1338]	[1047,1450,1487,1605]	-3	hSpCas9	negative selection	8471178
196801968	196801991	3	-	27260156	RDES	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.09732424632482906	[261]	[215,212,282,453]	-2	hSpCas9	negative selection	8535429
196805366	196805389	3	-	27260156	RDES	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.1386339636587386	[139]	[128,191,131,121]	-2	hSpCas9	negative selection	8535430
196805351	196805374	3	+	27260156	RDES	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.4067868878859533	[843]	[1133,1298,1197,1541]	6	hSpCas9	negative selection	8535431
196803023	196803046	3	-	27260156	PC3	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.32926048905913285	[1169]	[931,1363,2362,1654]	7	hSpCas9	negative selection	8592427
196803012	196803035	3	+	27260156	PC3	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.7038463438208757	[466]	[200,391,296,254]	-9	hSpCas9	negative selection	8592428
196801977	196802000	3	+	27260156	PC3	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.11680464575401106	[1338]	[763,1232,2164,1209]	-3	hSpCas9	negative selection	8592429
196801968	196801991	3	-	27260156	PC3	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.05471516141073074	[261]	[181,216,418,257]	-1	hSpCas9	negative selection	8656680
196805366	196805389	3	-	27260156	PC3	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.14850336445358026	[139]	[126,69,278,68]	-3	hSpCas9	negative selection	8656681
196805351	196805374	3	+	27260156	PC3	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.3903696710376998	[843]	[758,1263,1601,997]	7	hSpCas9	negative selection	8656682
196803023	196803046	3	-	27260156	PATU8988T	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	-0.013173688262860583	[1169]	[1234,1152,889,1216]	0	hSpCas9	negative selection	8713678
196803012	196803035	3	+	27260156	PATU8988T	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.6610490147534471	[466]	[295,388,246,213]	-7	hSpCas9	negative selection	8713679
196801977	196802000	3	+	27260156	PATU8988T	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.7025050097522957	[1338]	[1104,693,596,775]	-8	hSpCas9	negative selection	8713680
196801968	196801991	3	-	27260156	PATU8988T	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.5094678291144883	[261]	[164,97,219,223]	-7	hSpCas9	negative selection	8777931
196805366	196805389	3	-	27260156	PATU8988T	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.7556283195678222	[139]	[48,98,74,100]	-8	hSpCas9	negative selection	8777932
196805351	196805374	3	+	27260156	PATU8988T	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	-0.017662170512064423	[843]	[781,800,818,820]	0	hSpCas9	negative selection	8777933
196803023	196803046	3	-	27260156	T47D	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.184165016914432	[1169]	[1590,1380,1575,1663]	4	hSpCas9	negative selection	8834929
196803012	196803035	3	+	27260156	T47D	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.5401063917337187	[466]	[373,447,300,367]	-8	hSpCas9	negative selection	8834930
196801977	196802000	3	+	27260156	T47D	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.2918791406210022	[1338]	[1246,1283,1251,1313]	-6	hSpCas9	negative selection	8834931
196801968	196801991	3	-	27260156	T47D	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.06832448018166559	[261]	[248,293,314,305]	-1	hSpCas9	negative selection	8899182
196805366	196805389	3	-	27260156	T47D	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.3701760234030296	[139]	[142,146,98,113]	-7	hSpCas9	negative selection	8899183
196805351	196805374	3	+	27260156	T47D	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.2127578511874033	[843]	[1253,888,1262,1172]	4	hSpCas9	negative selection	8899184
196803023	196803046	3	-	27260156	SU8686	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.2336793479914283	[1169]	[1050,1259,1639,1587]	4	hSpCas9	negative selection	8956180
196803012	196803035	3	+	27260156	SU8686	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.8829874490334889	[466]	[296,211,259,229]	-8	hSpCas9	negative selection	8956181
196801977	196802000	3	+	27260156	SU8686	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.5076796563127666	[1338]	[958,862,994,915]	-7	hSpCas9	negative selection	8956182
196801968	196801991	3	-	27260156	SU8686	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.6307396303930575	[261]	[135,155,174,215]	-7	hSpCas9	negative selection	9020433
196805366	196805389	3	-	27260156	SU8686	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.7115515996780779	[139]	[56,68,65,163]	-8	hSpCas9	negative selection	9020434
196805351	196805374	3	+	27260156	SU8686	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	-0.011988194075477132	[843]	[859,700,829,955]	0	hSpCas9	negative selection	9020435
196803023	196803046	3	-	27260156	SKES1	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.2531820380857912	[1169]	[1481,1490,1448,1176]	5	hSpCas9	negative selection	9077431
196803012	196803035	3	+	27260156	SKES1	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.0643530950383132	[466]	[749,381,426,273]	-1	hSpCas9	negative selection	9077432
196801977	196802000	3	+	27260156	SKES1	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.18461239092325354	[1338]	[1605,1548,1582,1352]	4	hSpCas9	negative selection	9077433
196801968	196801991	3	-	27260156	SKES1	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.043251685469495094	[261]	[299,448,211,153]	1	hSpCas9	negative selection	9141684
196805366	196805389	3	-	27260156	SKES1	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.19924764710371456	[139]	[155,111,128,94]	-4	hSpCas9	negative selection	9141685
196805351	196805374	3	+	27260156	SKES1	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.47385058330492535	[843]	[1544,1178,1073,947]	8	hSpCas9	negative selection	9141686
196803023	196803046	3	-	27260156	TOV112D	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.22960491113429038	[1169]	[1264,1771,1157,1386]	4	hSpCas9	negative selection	9198682
196803012	196803035	3	+	27260156	TOV112D	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.510192160555585	[466]	[610,721,687,651]	8	hSpCas9	negative selection	9198683
196801977	196802000	3	+	27260156	TOV112D	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.6122591055227484	[1338]	[2238,2007,2038,1919]	9	hSpCas9	negative selection	9198684
196801968	196801991	3	-	27260156	TOV112D	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	0.3189458438511187	[261]	[380,282,296,340]	6	hSpCas9	negative selection	9262935
196805366	196805389	3	-	27260156	TOV112D	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.15571419357134175	[139]	[203,147,134,139]	3	hSpCas9	negative selection	9262936
196805351	196805374	3	+	27260156	TOV112D	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.46181396084817505	[843]	[1339,1166,1200,967]	8	hSpCas9	negative selection	9262937
196803023	196803046	3	-	27260156	TC71	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.16793276536540414	[1169]	[1263,1612,1283,1486]	4	hSpCas9	negative selection	9319933
196803012	196803035	3	+	27260156	TC71	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.2021135255553486	[466]	[335,494,499,407]	-5	hSpCas9	negative selection	9319934
196801977	196802000	3	+	27260156	TC71	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	0.16481582974334774	[1338]	[1761,1521,1479,1676]	4	hSpCas9	negative selection	9319935
196801968	196801991	3	-	27260156	TC71	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.052088862066966946	[261]	[273,275,279,251]	-1	hSpCas9	negative selection	9384186
196805366	196805389	3	-	27260156	TC71	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	-0.08619111735348084	[139]	[141,112,143,167]	-2	hSpCas9	negative selection	9384187
196805351	196805374	3	+	27260156	TC71	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.2231124594135323	[843]	[963,1080,1081,1100]	5	hSpCas9	negative selection	9384188
196803023	196803046	3	-	27260156	TC32	viability	AGTAATCGAGCCCACTGTTCTGG	PAK2	ENSG00000180370	0.3241336969295918	[1169]	[1335,1003,1791,1517]	6	hSpCas9	negative selection	9441184
196803012	196803035	3	+	27260156	TC32	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.23331504838633144	[466]	[350,205,564,454]	-4	hSpCas9	negative selection	9441185
196801977	196802000	3	+	27260156	TC32	viability	TTTGAGCACACCATCCATGTTGG	PAK2	ENSG00000180370	-0.0021112054877283626	[1338]	[1079,1321,1453,1109]	0	hSpCas9	negative selection	9441186
196801968	196801991	3	-	27260156	TC32	viability	ATGGTGTGCTCAAAATCAGATGG	PAK2	ENSG00000180370	-0.03503394192535403	[261]	[237,150,294,310]	0	hSpCas9	negative selection	9505437
196805366	196805389	3	-	27260156	TC32	viability	CTTACTGCTGGTGTTCCAGAAGG	PAK2	ENSG00000180370	0.362809759904239	[139]	[166,131,182,202]	6	hSpCas9	negative selection	9505438
196805351	196805374	3	+	27260156	TC32	viability	GAGAAAGATGGCTTTCCTTCTGG	PAK2	ENSG00000180370	0.1304121154266289	[843]	[605,646,1286,1085]	2	hSpCas9	negative selection	9505439
196803158	196803181	3	-	27869803	HPAFII	viability after 27 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-2.2521971368583156	[186]	[0,36,NaN]	-8	hSpCas9	negative selection	9584190
196806661	196806684	3	-	27869803	HPAFII	viability after 27 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.6748972681292116	[201]	[216,129,NaN]	5	hSpCas9	negative selection	9584191
196828315	196828338	3	+	27869803	HPAFII	viability after 27 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	1.197930871290719	[452]	[667,444,NaN]	8	hSpCas9	negative selection	9584192
196828322	196828345	3	-	27869803	HPAFII	viability after 27 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-1.3619261628192816	[191]	[35,41,NaN]	-7	hSpCas9	negative selection	9584193
196803158	196803181	3	-	27869803	HPAFII	viability after 15 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-0.9671921255118716	[186]	[87,111,NaN]	-7	hSpCas9	negative selection	9666639
196806661	196806684	3	-	27869803	HPAFII	viability after 15 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.3833098678769591	[201]	[432,189,NaN]	4	hSpCas9	negative selection	9666640
196828315	196828338	3	+	27869803	HPAFII	viability after 15 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.8353457086963093	[452]	[1221,648,NaN]	8	hSpCas9	negative selection	9666641
196828322	196828345	3	-	27869803	HPAFII	viability after 15 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-0.5132880570470466	[191]	[204,106,NaN]	-5	hSpCas9	negative selection	9666642
196803158	196803181	3	-	27869803	ASPC1	viability after 36 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-0.6721050700091077	[322]	[36,19,133]	-6	hSpCas9	negative selection	9749088
196806661	196806684	3	-	27869803	ASPC1	viability after 36 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.14568119908333227	[608]	[102,435,165]	1	hSpCas9	negative selection	9749089
196828315	196828338	3	+	27869803	ASPC1	viability after 36 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.2816690283870664	[1366]	[570,941,292]	3	hSpCas9	negative selection	9749090
196828322	196828345	3	-	27869803	ASPC1	viability after 36 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	0.41229442717084513	[512]	[199,378,150]	4	hSpCas9	negative selection	9749091
196803158	196803181	3	-	27869803	PATU8988S	viability after 35 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-1.2493550096998265	[400]	[38,96,NaN]	-8	hSpCas9	negative selection	9831537
196806661	196806684	3	-	27869803	PATU8988S	viability after 35 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.28906405361288934	[379]	[185,187,NaN]	3	hSpCas9	negative selection	9831538
196828315	196828338	3	+	27869803	PATU8988S	viability after 35 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.1296092806316842	[1344]	[643,540,NaN]	1	hSpCas9	negative selection	9831539
196828322	196828345	3	-	27869803	PATU8988S	viability after 35 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-0.5423233169424835	[549]	[197,105,NaN]	-5	hSpCas9	negative selection	9831540
196803158	196803181	3	-	27869803	PATU8988S	viability after 31 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-0.3008648248526892	[400]	[120,140,NaN]	-3	hSpCas9	negative selection	9913986
196806661	196806684	3	-	27869803	PATU8988S	viability after 31 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.525576035011683	[379]	[207,230,NaN]	6	hSpCas9	negative selection	9913987
196828315	196828338	3	+	27869803	PATU8988S	viability after 31 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.2510942793042312	[1344]	[577,714,NaN]	3	hSpCas9	negative selection	9913988
196828322	196828345	3	-	27869803	PATU8988S	viability after 31 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-0.47270862404772773	[549]	[139,180,NaN]	-5	hSpCas9	negative selection	9913989
196803158	196803181	3	-	27869803	HPAFII	viability after 35 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-1.6501430703341273	[186]	[0,62,NaN]	-7	hSpCas9	negative selection	9996435
196806661	196806684	3	-	27869803	HPAFII	viability after 35 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.7269480534180174	[201]	[212,119,NaN]	5	hSpCas9	negative selection	9996436
196828315	196828338	3	+	27869803	HPAFII	viability after 35 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	0.990785750531343	[452]	[522,379,NaN]	6	hSpCas9	negative selection	9996437
196828322	196828345	3	-	27869803	HPAFII	viability after 35 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-1.7684840945215587	[191]	[28,27,NaN]	-7	hSpCas9	negative selection	9996438
196803158	196803181	3	-	27869803	HPAFII	viability after 31 days	TATGCCACTCTCTTACCAGGAGG	PAK2	ENSG00000180370	-1.8438633257142607	[186]	[0,59,NaN]	-8	hSpCas9	negative selection	10078884
196806661	196806684	3	-	27869803	HPAFII	viability after 31 days	TTTCGTATGATCCGGTCGCGGGG	PAK2	ENSG00000180370	0.905217353946016	[201]	[263,155,NaN]	6	hSpCas9	negative selection	10078885
196828315	196828338	3	+	27869803	HPAFII	viability after 31 days	GCAGCATCCTTTCCTGAAACTGG	PAK2	ENSG00000180370	1.2079577872390876	[452]	[593,579,NaN]	8	hSpCas9	negative selection	10078886
196828322	196828345	3	-	27869803	HPAFII	viability after 31 days	GGTTTGGCCAGTTTCAGGAAAGG	PAK2	ENSG00000180370	-0.6514546297604487	[191]	[81,53,NaN]	-4	hSpCas9	negative selection	10078887
196806648	196806671	3	-	28162770	P31FUJ	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-1.8608334270274205	[33]	[10]	-8	hSpCas9	negative selection	10206442
196820504	196820527	3	+	28162770	P31FUJ	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	2.4480353773733174	[227]	[1461]	9	hSpCas9	negative selection	10206443
196820438	196820461	3	+	28162770	P31FUJ	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-1.462284050537146	[135]	[57]	-7	hSpCas9	negative selection	10206444
196803012	196803035	3	+	28162770	P31FUJ	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.46800862499329726	[298]	[485]	5	hSpCas9	negative selection	10206445
196803086	196803109	3	-	28162770	P31FUJ	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.20563200324890846	[262]	[267]	-2	hSpCas9	negative selection	10206446
196806569	196806592	3	+	28162770	P31FUJ	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	0.38741114348982963	[282]	[434]	4	hSpCas9	negative selection	10206447
196814478	196814501	3	+	28162770	P31FUJ	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-1.5688514075463937	[153]	[60]	-7	hSpCas9	negative selection	10206448
196820405	196820428	3	+	28162770	P31FUJ	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	0.5405559012478158	[594]	[1016]	6	hSpCas9	negative selection	10206449
196782686	196782709	3	-	28162770	P31FUJ	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	-5.232802204414378	[31]	[0]	-9	hSpCas9	negative selection	10206450
196782761	196782784	3	-	28162770	P31FUJ	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	1.9766511612145714	[15]	[73]	9	hSpCas9	negative selection	10206451
196806648	196806671	3	-	28162770	TF1	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10375808
196820504	196820527	3	+	28162770	TF1	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10375809
196820438	196820461	3	+	28162770	TF1	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10375810
196803012	196803035	3	+	28162770	TF1	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10375811
196803086	196803109	3	-	28162770	TF1	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10375812
196806569	196806592	3	+	28162770	TF1	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	NaN	[NaN]	[193]	1	hSpCas9	negative selection	10375813
196814478	196814501	3	+	28162770	TF1	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10375814
196820405	196820428	3	+	28162770	TF1	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	NaN	[NaN]	[373]	1	hSpCas9	negative selection	10375815
196782686	196782709	3	-	28162770	TF1	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	NaN	[NaN]	[25]	1	hSpCas9	negative selection	10375816
196782761	196782784	3	-	28162770	TF1	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10375817
196806648	196806671	3	-	28162770	SKM1	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-0.9919266994643179	[8]	[7]	-6	hSpCas9	negative selection	10545174
196820504	196820527	3	+	28162770	SKM1	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	-2.9374789154419414	[51]	[11]	-9	hSpCas9	negative selection	10545175
196820438	196820461	3	+	28162770	SKM1	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-1.5996092766855576	[23]	[13]	-8	hSpCas9	negative selection	10545176
196803012	196803035	3	+	28162770	SKM1	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-1.6699986045769555	[80]	[44]	-8	hSpCas9	negative selection	10545177
196803086	196803109	3	-	28162770	SKM1	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.6313181364128957	[91]	[104]	-5	hSpCas9	negative selection	10545178
196806569	196806592	3	+	28162770	SKM1	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	-0.6096980943091413	[81]	[94]	-5	hSpCas9	negative selection	10545179
196814478	196814501	3	+	28162770	SKM1	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-1.9215373715729203	[29]	[13]	-8	hSpCas9	negative selection	10545180
196820405	196820428	3	+	28162770	SKM1	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	-1.8123515279882862	[148]	[74]	-8	hSpCas9	negative selection	10545181
196782686	196782709	3	-	28162770	SKM1	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	-0.2370391973008492	[3]	[5]	-2	hSpCas9	negative selection	10545182
196782761	196782784	3	-	28162770	SKM1	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	0.17799830197799427	[2]	[5]	1	hSpCas9	negative selection	10545183
196806648	196806671	3	-	28162770	SKM1	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-0.9919266994643179	[8]	[7]	-6	hSpCas9	negative selection	10714540
196820504	196820527	3	+	28162770	SKM1	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	-2.9374789154419414	[51]	[11]	-9	hSpCas9	negative selection	10714541
196820438	196820461	3	+	28162770	SKM1	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-1.5996092766855576	[23]	[13]	-8	hSpCas9	negative selection	10714542
196803012	196803035	3	+	28162770	SKM1	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-1.6699986045769555	[80]	[44]	-8	hSpCas9	negative selection	10714543
196803086	196803109	3	-	28162770	SKM1	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.6313181364128957	[91]	[104]	-5	hSpCas9	negative selection	10714544
196806569	196806592	3	+	28162770	SKM1	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	-0.6096980943091413	[81]	[94]	-5	hSpCas9	negative selection	10714545
196814478	196814501	3	+	28162770	SKM1	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-1.9215373715729203	[29]	[13]	-8	hSpCas9	negative selection	10714546
196820405	196820428	3	+	28162770	SKM1	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	-1.8123515279882862	[148]	[74]	-8	hSpCas9	negative selection	10714547
196782686	196782709	3	-	28162770	SKM1	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	-0.2370391973008492	[3]	[5]	-2	hSpCas9	negative selection	10714548
196782761	196782784	3	-	28162770	SKM1	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	0.17799830197799427	[2]	[5]	1	hSpCas9	negative selection	10714549
196806648	196806671	3	-	28162770	PL21	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-0.38482288623183614	[20]	[6]	-3	hSpCas9	negative selection	10883906
196820504	196820527	3	+	28162770	PL21	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	-1.9804326311525005	[135]	[14]	-8	hSpCas9	negative selection	10883907
196820438	196820461	3	+	28162770	PL21	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-0.7357300480909641	[87]	[22]	-5	hSpCas9	negative selection	10883908
196803012	196803035	3	+	28162770	PL21	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.6668582539956855	[320]	[87]	-5	hSpCas9	negative selection	10883909
196803086	196803109	3	-	28162770	PL21	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.2990930122059521	[293]	[103]	-2	hSpCas9	negative selection	10883910
196806569	196806592	3	+	28162770	PL21	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	1.3063983018798775	[313]	[337]	9	hSpCas9	negative selection	10883911
196814478	196814501	3	+	28162770	PL21	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-0.8354842952414014	[163]	[39]	-5	hSpCas9	negative selection	10883912
196820405	196820428	3	+	28162770	PL21	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	-1.232819792786786	[512]	[94]	-7	hSpCas9	negative selection	10883913
196782686	196782709	3	-	28162770	PL21	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	-2.9697853869529927	[17]	[0]	-9	hSpCas9	negative selection	10883914
196782761	196782784	3	-	28162770	PL21	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	-0.5368259796768866	[9]	[2]	-4	hSpCas9	negative selection	10883915
196806648	196806671	3	-	28162770	P31FUJ	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-1.8608334270274205	[33]	[10]	-8	hSpCas9	negative selection	11053272
196820504	196820527	3	+	28162770	P31FUJ	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	2.4480353773733174	[227]	[1461]	9	hSpCas9	negative selection	11053273
196820438	196820461	3	+	28162770	P31FUJ	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-1.462284050537146	[135]	[57]	-7	hSpCas9	negative selection	11053274
196803012	196803035	3	+	28162770	P31FUJ	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.46800862499329726	[298]	[485]	5	hSpCas9	negative selection	11053275
196803086	196803109	3	-	28162770	P31FUJ	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.20563200324890846	[262]	[267]	-2	hSpCas9	negative selection	11053276
196806569	196806592	3	+	28162770	P31FUJ	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	0.38741114348982963	[282]	[434]	4	hSpCas9	negative selection	11053277
196814478	196814501	3	+	28162770	P31FUJ	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-1.5688514075463937	[153]	[60]	-7	hSpCas9	negative selection	11053278
196820405	196820428	3	+	28162770	P31FUJ	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	0.5405559012478158	[594]	[1016]	6	hSpCas9	negative selection	11053279
196782686	196782709	3	-	28162770	P31FUJ	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	-5.232802204414378	[31]	[0]	-9	hSpCas9	negative selection	11053280
196782761	196782784	3	-	28162770	P31FUJ	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	1.9766511612145714	[15]	[73]	9	hSpCas9	negative selection	11053281
196806648	196806671	3	-	28162770	OCIAML5	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-1.4370290715851537	[2]	[1]	-7	hSpCas9	negative selection	11222638
196820504	196820527	3	+	28162770	OCIAML5	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	-1.1667630965202835	[198]	[159]	-6	hSpCas9	negative selection	11222639
196820438	196820461	3	+	28162770	OCIAML5	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-2.769604410672024	[101]	[26]	-8	hSpCas9	negative selection	11222640
196803012	196803035	3	+	28162770	OCIAML5	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.7446491112828367	[162]	[492]	6	hSpCas9	negative selection	11222641
196803086	196803109	3	-	28162770	OCIAML5	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-1.2271060022109217	[165]	[127]	-6	hSpCas9	negative selection	11222642
196806569	196806592	3	+	28162770	OCIAML5	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	0.9419915285801493	[108]	[377]	7	hSpCas9	negative selection	11222643
196814478	196814501	3	+	28162770	OCIAML5	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-2.0696580059366236	[99]	[42]	-8	hSpCas9	negative selection	11222644
196820405	196820428	3	+	28162770	OCIAML5	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	-0.5706536357153487	[454]	[552]	-4	hSpCas9	negative selection	11222645
196782686	196782709	3	-	28162770	OCIAML5	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	0.1271748689692056	[34]	[68]	1	hSpCas9	negative selection	11222646
196782761	196782784	3	-	28162770	OCIAML5	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11222647
196806648	196806671	3	-	28162770	EOL1	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-1.5348838470667627	[43]	[7]	-7	hSpCas9	negative selection	11392004
196820504	196820527	3	+	28162770	EOL1	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	0.5657543829313099	[217]	[169]	5	hSpCas9	negative selection	11392005
196820438	196820461	3	+	28162770	EOL1	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-0.6124802520869197	[147]	[50]	-4	hSpCas9	negative selection	11392006
196803012	196803035	3	+	28162770	EOL1	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.13884730971797465	[534]	[255]	-1	hSpCas9	negative selection	11392007
196803086	196803109	3	-	28162770	EOL1	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.29696736482499253	[547]	[234]	-2	hSpCas9	negative selection	11392008
196806569	196806592	3	+	28162770	EOL1	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	0.1426220363132935	[477]	[277]	1	hSpCas9	negative selection	11392009
196814478	196814501	3	+	28162770	EOL1	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-2.3099174820664885	[159]	[16]	-8	hSpCas9	negative selection	11392010
196820405	196820428	3	+	28162770	EOL1	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	0.4027035457646724	[681]	[474]	3	hSpCas9	negative selection	11392011
196782686	196782709	3	-	28162770	EOL1	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	-0.7859456112344807	[35]	[10]	-5	hSpCas9	negative selection	11392012
196782761	196782784	3	-	28162770	EOL1	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	-1.323379741873051	[18]	[3]	-7	hSpCas9	negative selection	11392013
196806648	196806671	3	-	28162770	MOLM13	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	0.39750005365318053	[41]	[39]	3	hSpCas9	negative selection	11561370
196820504	196820527	3	+	28162770	MOLM13	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	0.6510116853684681	[265]	[301]	5	hSpCas9	negative selection	11561371
196820438	196820461	3	+	28162770	MOLM13	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-0.43481341710050647	[128]	[68]	-3	hSpCas9	negative selection	11561372
196803012	196803035	3	+	28162770	MOLM13	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.8923200157807328	[420]	[564]	6	hSpCas9	negative selection	11561373
196803086	196803109	3	-	28162770	MOLM13	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.012872299957101374	[493]	[353]	0	hSpCas9	negative selection	11561374
196806569	196806592	3	+	28162770	MOLM13	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	1.1664469141076945	[471]	[765]	8	hSpCas9	negative selection	11561375
196814478	196814501	3	+	28162770	MOLM13	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-0.6974483504020816	[156]	[69]	-4	hSpCas9	negative selection	11561376
196820405	196820428	3	+	28162770	MOLM13	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	0.20647507137894672	[711]	[593]	1	hSpCas9	negative selection	11561377
196782686	196782709	3	-	28162770	MOLM13	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	1.4436418352979015	[29]	[58]	9	hSpCas9	negative selection	11561378
196782761	196782784	3	-	28162770	MOLM13	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	-4.532110618455421	[31]	[0]	-9	hSpCas9	negative selection	11561379
196806648	196806671	3	-	28162770	HEL	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-0.35726116799964336	[23]	[11]	-3	hSpCas9	negative selection	11730736
196820504	196820527	3	+	28162770	HEL	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	0.32738339103648084	[218]	[175]	2	hSpCas9	negative selection	11730737
196820438	196820461	3	+	28162770	HEL	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-0.7435396742970627	[148]	[56]	-5	hSpCas9	negative selection	11730738
196803012	196803035	3	+	28162770	HEL	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.20688286121395882	[348]	[257]	1	hSpCas9	negative selection	11730739
196803086	196803109	3	-	28162770	HEL	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.3148259016792464	[401]	[206]	-2	hSpCas9	negative selection	11730740
196806569	196806592	3	+	28162770	HEL	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	0.8378933818589887	[358]	[410]	7	hSpCas9	negative selection	11730741
196814478	196814501	3	+	28162770	HEL	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	0.21102259157488268	[115]	[85]	1	hSpCas9	negative selection	11730742
196820405	196820428	3	+	28162770	HEL	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	0.06020715753396266	[592]	[395]	0	hSpCas9	negative selection	11730743
196782686	196782709	3	-	28162770	HEL	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	-3.3114574783865183	[30]	[1]	-9	hSpCas9	negative selection	11730744
196782761	196782784	3	-	28162770	HEL	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	0.2707700546133993	[21]	[16]	2	hSpCas9	negative selection	11730745
196806648	196806671	3	-	28162770	MV411	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-1.0004899626608101	[18]	[7]	-6	hSpCas9	negative selection	11900102
196820504	196820527	3	+	28162770	MV411	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	-0.0529573825549457	[132]	[107]	0	hSpCas9	negative selection	11900103
196820438	196820461	3	+	28162770	MV411	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-0.04895545199744955	[69]	[56]	0	hSpCas9	negative selection	11900104
196803012	196803035	3	+	28162770	MV411	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.680669530735439	[273]	[143]	-5	hSpCas9	negative selection	11900105
196803086	196803109	3	-	28162770	MV411	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.35682550589731726	[300]	[197]	-3	hSpCas9	negative selection	11900106
196806569	196806592	3	+	28162770	MV411	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	-0.24732714096680253	[309]	[219]	-2	hSpCas9	negative selection	11900107
196814478	196814501	3	+	28162770	MV411	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-0.806001708178685	[109]	[52]	-5	hSpCas9	negative selection	11900108
196820405	196820428	3	+	28162770	MV411	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	-0.19478477782229886	[499]	[367]	-1	hSpCas9	negative selection	11900109
196782686	196782709	3	-	28162770	MV411	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	2.083938818499896	[13]	[49]	9	hSpCas9	negative selection	11900110
196782761	196782784	3	-	28162770	MV411	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	-0.07449054410458711	[24]	[19]	0	hSpCas9	negative selection	11900111
196806648	196806671	3	-	28162770	MONOMAC1	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-0.38968192500194965	[15]	[13]	-3	hSpCas9	negative selection	12069468
196820504	196820527	3	+	28162770	MONOMAC1	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	-0.02555637911519998	[102]	[115]	0	hSpCas9	negative selection	12069469
196820438	196820461	3	+	28162770	MONOMAC1	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-0.5125386727874828	[55]	[44]	-4	hSpCas9	negative selection	12069470
196803012	196803035	3	+	28162770	MONOMAC1	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	0.4113846264855915	[182]	[278]	4	hSpCas9	negative selection	12069471
196803086	196803109	3	-	28162770	MONOMAC1	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-0.1806424088088852	[174]	[176]	-1	hSpCas9	negative selection	12069472
196806569	196806592	3	+	28162770	MONOMAC1	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	0.5208829914161058	[182]	[300]	5	hSpCas9	negative selection	12069473
196814478	196814501	3	+	28162770	MONOMAC1	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-0.3513649934508476	[68]	[61]	-3	hSpCas9	negative selection	12069474
196820405	196820428	3	+	28162770	MONOMAC1	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	0.10925683188583957	[333]	[412]	1	hSpCas9	negative selection	12069475
196782686	196782709	3	-	28162770	MONOMAC1	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	0.7155003116901066	[16]	[31]	6	hSpCas9	negative selection	12069476
196782761	196782784	3	-	28162770	MONOMAC1	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	0.6609441480680185	[15]	[28]	6	hSpCas9	negative selection	12069477
196806648	196806671	3	-	28162770	OCIAML2	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	-2.148701730354799	[11]	[14]	-8	hSpCas9	negative selection	12238834
196820504	196820527	3	+	28162770	OCIAML2	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	-0.7996941014111522	[37]	[120]	-5	hSpCas9	negative selection	12238835
196820438	196820461	3	+	28162770	OCIAML2	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	-0.6310944974354072	[18]	[67]	-5	hSpCas9	negative selection	12238836
196803012	196803035	3	+	28162770	OCIAML2	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	-0.9644444379051221	[68]	[195]	-6	hSpCas9	negative selection	12238837
196803086	196803109	3	-	28162770	OCIAML2	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	-1.4035156293836244	[62]	[131]	-7	hSpCas9	negative selection	12238838
196806569	196806592	3	+	28162770	OCIAML2	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	0.038781642471818256	[48]	[278]	0	hSpCas9	negative selection	12238839
196814478	196814501	3	+	28162770	OCIAML2	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-3.9035892325182675	[26]	[9]	-9	hSpCas9	negative selection	12238840
196820405	196820428	3	+	28162770	OCIAML2	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	0.2551952113188447	[90]	[601]	2	hSpCas9	negative selection	12238841
196782686	196782709	3	-	28162770	OCIAML2	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	-1.1487017303547988	[5]	[14]	-6	hSpCas9	negative selection	12238842
196782761	196782784	3	-	28162770	OCIAML2	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	1.616833016008178	[0]	[16]	9	hSpCas9	negative selection	12238843
196806648	196806671	3	-	28162770	OCIAML3	viability	GGTCGCGGGGCAATAACGGGAGG	PAK2	ENSG00000180370	0.5214695770957727	[2]	[12]	5	hSpCas9	negative selection	12408200
196820504	196820527	3	+	28162770	OCIAML3	viability	GGGTATCATGGCTATTGAGATGG	PAK2	ENSG00000180370	-0.053439258961460415	[54]	[159]	0	hSpCas9	negative selection	12408201
196820438	196820461	3	+	28162770	OCIAML3	viability	ATACTGGATGGCACCAGAGGTGG	PAK2	ENSG00000180370	0.8552997610394266	[25]	[141]	7	hSpCas9	negative selection	12408202
196803012	196803035	3	+	28162770	OCIAML3	viability	GTTAGGGCATGCCAGAACAGTGG	PAK2	ENSG00000180370	1.1237100692487645	[82]	[545]	8	hSpCas9	negative selection	12408203
196803086	196803109	3	-	28162770	OCIAML3	viability	AGGACATCCAGCACAGCCTGAGG	PAK2	ENSG00000180370	0.26848883592590184	[43]	[159]	2	hSpCas9	negative selection	12408204
196806569	196806592	3	+	28162770	OCIAML3	viability	ATCAATGCAGCTGAATGCCAAGG	PAK2	ENSG00000180370	-0.19088346258881989	[75]	[200]	-1	hSpCas9	negative selection	12408205
196814478	196814501	3	+	28162770	OCIAML3	viability	GGTCATGGAATACCTTGCTGGGG	PAK2	ENSG00000180370	-0.34346417867356616	[28]	[68]	-3	hSpCas9	negative selection	12408206
196820405	196820428	3	+	28162770	OCIAML3	viability	GCAGAGCAAACGCAGTACCATGG	PAK2	ENSG00000180370	0.22215317910878185	[139]	[492]	2	hSpCas9	negative selection	12408207
196782686	196782709	3	-	28162770	OCIAML3	viability	GTGCTGCTCATTCGCACAGGAGG	PAK2	ENSG00000180370	-1.442004546879113	[8]	[9]	-7	hSpCas9	negative selection	12408208
196782761	196782784	3	-	28162770	OCIAML3	viability	TCTTCTGGAACAGAGGGCAAAGG	PAK2	ENSG00000180370	-0.594007640324163	[1]	[3]	-4	hSpCas9	negative selection	12408209