Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:56924
• Symbol:PAK6
• Description:p21 (RAC1) activated kinase 6

DataSource: http://genomecrispr.dkfz.de/#!/results/PAK6

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
40272880	40272903	15	+	26472758	Jiyoye	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.35682118161882403	[378]	[365]	2	hSpCas9	negative selection	115560
40264968	40264991	15	+	26472758	Jiyoye	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-1.1084660587113762	[385]	[134]	-6	hSpCas9	negative selection	115561
40266056	40266079	15	-	26472758	Jiyoye	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	0.3903015629414772	[85]	[84]	3	hSpCas9	negative selection	115562
40266095	40266118	15	+	26472758	Jiyoye	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	0.07404908001364718	[193]	[153]	0	hSpCas9	negative selection	115563
40266392	40266415	15	+	26472758	Jiyoye	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	1.1247756508051485	[44]	[73]	7	hSpCas9	negative selection	115564
40272643	40272666	15	+	26472758	Jiyoye	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	0.8866447533797157	[103]	[144]	6	hSpCas9	negative selection	115565
40273366	40273389	15	-	26472758	Jiyoye	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	-2.082209459233052	[72]	[12]	-8	hSpCas9	negative selection	115566
40274193	40274216	15	-	26472758	Jiyoye	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-0.9584740908108071	[133]	[51]	-6	hSpCas9	negative selection	115567
40264907	40264930	15	+	26472758	Jiyoye	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-1.2373439638957378	[271]	[86]	-7	hSpCas9	negative selection	115568
40264940	40264963	15	-	26472758	Jiyoye	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.06930574274948942	[181]	[143]	0	hSpCas9	negative selection	115569
40272880	40272903	15	+	26472758	KBM7	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.2462705298288409	[936,619]	[365,481]	2	hSpCas9	negative selection	306678
40264968	40264991	15	+	26472758	KBM7	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-0.2030025593118987	[885,886]	[280,437]	-2	hSpCas9	negative selection	306679
40266056	40266079	15	-	26472758	KBM7	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-1.089104318887055	[427,343]	[88,80]	-7	hSpCas9	negative selection	306680
40266095	40266118	15	+	26472758	KBM7	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	0.12615031488832562	[558,385]	[340,147]	1	hSpCas9	negative selection	306681
40266392	40266415	15	+	26472758	KBM7	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	-0.7324277092856011	[168,107]	[28,46]	-6	hSpCas9	negative selection	306682
40272643	40272666	15	+	26472758	KBM7	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	0.2925897384326019	[666,245]	[170,323]	3	hSpCas9	negative selection	306683
40273366	40273389	15	-	26472758	KBM7	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	0.9187421728045937	[50,91]	[51,77]	8	hSpCas9	negative selection	306684
40274193	40274216	15	-	26472758	KBM7	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-0.8351591636005876	[380,368]	[67,126]	-6	hSpCas9	negative selection	306685
40264907	40264930	15	+	26472758	KBM7	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.22110759937630842	[812,979]	[454,287]	-2	hSpCas9	negative selection	306686
40264940	40264963	15	-	26472758	KBM7	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.23172294076350686	[870,669]	[453,392]	2	hSpCas9	negative selection	306687
40272880	40272903	15	+	26472758	Raji	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.4437805854128787	[376]	[118]	4	hSpCas9	negative selection	497796
40264968	40264991	15	+	26472758	Raji	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-0.013246169811939268	[560]	[128]	0	hSpCas9	negative selection	497797
40266056	40266079	15	-	26472758	Raji	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-1.6223504895615308	[198]	[14]	-8	hSpCas9	negative selection	497798
40266095	40266118	15	+	26472758	Raji	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	-0.717044900042946	[254]	[35]	-5	hSpCas9	negative selection	497799
40266392	40266415	15	+	26472758	Raji	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	0.4553068387939063	[43]	[13]	4	hSpCas9	negative selection	497800
40272643	40272666	15	+	26472758	Raji	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	0.7288719121198696	[220]	[84]	6	hSpCas9	negative selection	497801
40273366	40273389	15	-	26472758	Raji	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	-0.16945666998522446	[62]	[12]	-1	hSpCas9	negative selection	497802
40274193	40274216	15	-	26472758	Raji	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-0.38904229074589924	[236]	[41]	-3	hSpCas9	negative selection	497803
40264907	40264930	15	+	26472758	Raji	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.15931132741746046	[381]	[98]	1	hSpCas9	negative selection	497804
40264940	40264963	15	-	26472758	Raji	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.47935231276055745	[271]	[87]	4	hSpCas9	negative selection	497805
40272880	40272903	15	+	26472758	K562	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.25739658166465673	[663]	[669]	2	hSpCas9	negative selection	688914
40264968	40264991	15	+	26472758	K562	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-0.4332789860186258	[770]	[481]	-3	hSpCas9	negative selection	688915
40266056	40266079	15	-	26472758	K562	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	0.08395405547320067	[227]	[203]	0	hSpCas9	negative selection	688916
40266095	40266118	15	+	26472758	K562	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	0.7770601932575206	[364]	[527]	6	hSpCas9	negative selection	688917
40266392	40266415	15	+	26472758	K562	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	0.4199902922499015	[84]	[95]	3	hSpCas9	negative selection	688918
40272643	40272666	15	+	26472758	K562	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	-0.204888673697143	[425]	[311]	-1	hSpCas9	negative selection	688919
40273366	40273389	15	-	26472758	K562	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	-0.25153876699596456	[54]	[38]	-2	hSpCas9	negative selection	688920
40274193	40274216	15	-	26472758	K562	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-0.08725734377247774	[296]	[235]	0	hSpCas9	negative selection	688921
40264907	40264930	15	+	26472758	K562	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.1048849861836133	[639]	[580]	0	hSpCas9	negative selection	688922
40264940	40264963	15	-	26472758	K562	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.4206852559825859	[453]	[512]	3	hSpCas9	negative selection	688923
40264947	40264970	15	+	26627737	DLD1	viability	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.17894015984881623	[685]	[96,212,249]	-2	hSpCas9	negative selection	790371
40266064	40266087	15	+	26627737	DLD1	viability	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	0.5407118747548298	[1844]	[870,965,705]	5	hSpCas9	negative selection	790372
40272574	40272597	15	-	26627737	DLD1	viability	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	-0.03765090047969388	[149]	[73,69,0]	0	hSpCas9	negative selection	790373
40272880	40272903	15	+	26627737	DLD1	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.05705849308340194	[1744]	[666,702,368]	0	hSpCas9	negative selection	790374
40274214	40274237	15	-	26627737	DLD1	viability	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.39263774803088747	[204]	[80,95,76]	4	hSpCas9	negative selection	790375
40276061	40276084	15	-	26627737	DLD1	viability	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	1.0018138410508897	[224]	[129,151,140]	8	hSpCas9	negative selection	790376
40264947	40264970	15	+	26627737	GBM cells	viability after 5 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.3383695365572433	[210]	[75,102]	-5	hSpCas9	negative selection	872686
40266064	40266087	15	+	26627737	GBM cells	viability after 5 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	0.08579200960919509	[751]	[418,436]	1	hSpCas9	negative selection	872687
40272574	40272597	15	-	26627737	GBM cells	viability after 5 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.1333791285227084	[118]	[109,29]	2	hSpCas9	negative selection	872688
40272880	40272903	15	+	26627737	GBM cells	viability after 5 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.26654201377810405	[695]	[458,438]	4	hSpCas9	negative selection	872689
40274214	40274237	15	-	26627737	GBM cells	viability after 5 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	1.0232420098878874	[49]	[59,48]	9	hSpCas9	negative selection	872690
40276061	40276084	15	-	26627737	GBM cells	viability after 5 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	0.6530036468431011	[200]	[164,173]	8	hSpCas9	negative selection	872691
40264947	40264970	15	+	26627737	GBM cells	viability after 13 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.4358586933594844	[210]	[109,63]	-5	hSpCas9	negative selection	955001
40266064	40266087	15	+	26627737	GBM cells	viability after 13 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.0020117146921294626	[751]	[482,345]	0	hSpCas9	negative selection	955002
40272574	40272597	15	-	26627737	GBM cells	viability after 13 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.5594840027082418	[118]	[130,65]	7	hSpCas9	negative selection	955003
40272880	40272903	15	+	26627737	GBM cells	viability after 13 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.31908067383679617	[695]	[560,397]	4	hSpCas9	negative selection	955004
40274214	40274237	15	-	26627737	GBM cells	viability after 13 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.13020928788485664	[49]	[32,26]	1	hSpCas9	negative selection	955005
40276061	40276084	15	-	26627737	GBM cells	viability after 13 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	0.21119101003867594	[200]	[144,110]	2	hSpCas9	negative selection	955006
40264947	40264970	15	+	26627737	GBM cells	viability after 21 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.7562346386243501	[210]	[70,64]	-6	hSpCas9	negative selection	1037316
40266064	40266087	15	+	26627737	GBM cells	viability after 21 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	0.18231204819388158	[751]	[496,432]	2	hSpCas9	negative selection	1037317
40272574	40272597	15	-	26627737	GBM cells	viability after 21 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.7258334533969403	[118]	[96,115]	7	hSpCas9	negative selection	1037318
40272880	40272903	15	+	26627737	GBM cells	viability after 21 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.5731130760875096	[695]	[584,541]	6	hSpCas9	negative selection	1037319
40274214	40274237	15	-	26627737	GBM cells	viability after 21 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.7710474560310248	[49]	[37,53]	7	hSpCas9	negative selection	1037320
40276061	40276084	15	-	26627737	GBM cells	viability after 21 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	0.3547959774012516	[200]	[147,131]	3	hSpCas9	negative selection	1037321
40264947	40264970	15	+	26627737	RPE1	viability after 9 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.10385419909365479	[632]	[169,202]	0	hSpCas9	negative selection	1119631
40266064	40266087	15	+	26627737	RPE1	viability after 9 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	0.3239355299157234	[2357]	[1168,607]	2	hSpCas9	negative selection	1119632
40272574	40272597	15	-	26627737	RPE1	viability after 9 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	-0.11002174136196463	[333]	[102,88]	-1	hSpCas9	negative selection	1119633
40272880	40272903	15	+	26627737	RPE1	viability after 9 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.46895681138136247	[4378]	[793,1243]	-3	hSpCas9	negative selection	1119634
40274214	40274237	15	-	26627737	RPE1	viability after 9 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.5707120489522939	[423]	[87,337]	4	hSpCas9	negative selection	1119635
40276061	40276084	15	-	26627737	RPE1	viability after 9 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.8355475152466789	[758]	[116,153]	-5	hSpCas9	negative selection	1119636
40264947	40264970	15	+	26627737	RPE1	viability after 12 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	0.2757496417266205	[632]	[235,173]	1	hSpCas9	negative selection	1201946
40266064	40266087	15	+	26627737	RPE1	viability after 12 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	0.23291912992345765	[2357]	[761,725]	1	hSpCas9	negative selection	1201947
40272574	40272597	15	-	26627737	RPE1	viability after 12 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	-0.7472820545050967	[333]	[51,54]	-5	hSpCas9	negative selection	1201948
40272880	40272903	15	+	26627737	RPE1	viability after 12 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.32722576419170313	[4378]	[945,928]	-2	hSpCas9	negative selection	1201949
40274214	40274237	15	-	26627737	RPE1	viability after 12 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	1.0213668202923283	[423]	[119,348]	6	hSpCas9	negative selection	1201950
40276061	40276084	15	-	26627737	RPE1	viability after 12 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.44055489920660074	[758]	[158,140]	-3	hSpCas9	negative selection	1201951
40264947	40264970	15	+	26627737	RPE1	viability after 15 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	0.7565648351056152	[632]	[413,194]	4	hSpCas9	negative selection	1284261
40266064	40266087	15	+	26627737	RPE1	viability after 15 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.4745385426849702	[2357]	[279,672]	-3	hSpCas9	negative selection	1284262
40272574	40272597	15	-	26627737	RPE1	viability after 15 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.9519061252739662	[333]	[223,142]	6	hSpCas9	negative selection	1284263
40272880	40272903	15	+	26627737	RPE1	viability after 15 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.0383033392811285	[4378]	[1359,1057]	0	hSpCas9	negative selection	1284264
40274214	40274237	15	-	26627737	RPE1	viability after 15 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	1.1001640185098363	[423]	[249,263]	6	hSpCas9	negative selection	1284265
40276061	40276084	15	-	26627737	RPE1	viability after 15 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.46428241799674064	[758]	[232,80]	-3	hSpCas9	negative selection	1284266
40264947	40264970	15	+	26627737	RPE1	viability after 18 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.11586194689138679	[632]	[190,121]	0	hSpCas9	negative selection	1366576
40266064	40266087	15	+	26627737	RPE1	viability after 18 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	0.3441593572149333	[2357]	[859,751]	2	hSpCas9	negative selection	1366577
40272574	40272597	15	-	26627737	RPE1	viability after 18 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.6323136829019371	[333]	[145,132]	4	hSpCas9	negative selection	1366578
40272880	40272903	15	+	26627737	RPE1	viability after 18 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.29564502737243004	[4378]	[839,1093]	-2	hSpCas9	negative selection	1366579
40274214	40274237	15	-	26627737	RPE1	viability after 18 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.7561873937860596	[423]	[98,293]	4	hSpCas9	negative selection	1366580
40276061	40276084	15	-	26627737	RPE1	viability after 18 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.6356559247146346	[758]	[97,167]	-4	hSpCas9	negative selection	1366581
40264947	40264970	15	+	26627737	HeLa	viability after 8 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-1.960019319880654	[328]	[64,5,44]	-9	hSpCas9	negative selection	1448891
40266064	40266087	15	+	26627737	HeLa	viability after 8 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-1.722117997025354	[2341]	[251,365,296]	-9	hSpCas9	negative selection	1448892
40272574	40272597	15	-	26627737	HeLa	viability after 8 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.5829007643019426	[155]	[142,37,130]	5	hSpCas9	negative selection	1448893
40272880	40272903	15	+	26627737	HeLa	viability after 8 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.14709199244169247	[849]	[587,270,408]	1	hSpCas9	negative selection	1448894
40274214	40274237	15	-	26627737	HeLa	viability after 8 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	1.1341618417417652	[129]	[208,114,70]	8	hSpCas9	negative selection	1448895
40276061	40276084	15	-	26627737	HeLa	viability after 8 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.2785177576717108	[468]	[154,269,82]	-3	hSpCas9	negative selection	1448896
40264947	40264970	15	+	26627737	HeLa	viability after 12 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.22975347178013245	[328]	[131,99,117]	-2	hSpCas9	negative selection	1531206
40266064	40266087	15	+	26627737	HeLa	viability after 12 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-1.2938442346688337	[2341]	[370,437,369]	-8	hSpCas9	negative selection	1531207
40272574	40272597	15	-	26627737	HeLa	viability after 12 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	-0.6453248644920171	[155]	[31,25,66]	-5	hSpCas9	negative selection	1531208
40272880	40272903	15	+	26627737	HeLa	viability after 12 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.39568849844279597	[849]	[516,527,335]	3	hSpCas9	negative selection	1531209
40274214	40274237	15	-	26627737	HeLa	viability after 12 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	1.6168804051678716	[129]	[145,209,132]	9	hSpCas9	negative selection	1531210
40276061	40276084	15	-	26627737	HeLa	viability after 12 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.19152900034763506	[468]	[181,136,193]	-2	hSpCas9	negative selection	1531211
40264947	40264970	15	+	26627737	HeLa	viability after 15 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.9240996397515068	[328]	[46,58,108]	-7	hSpCas9	negative selection	1613521
40266064	40266087	15	+	26627737	HeLa	viability after 15 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-1.5508481784976293	[2341]	[205,310,471]	-8	hSpCas9	negative selection	1613522
40272574	40272597	15	-	26627737	HeLa	viability after 15 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	-1.1316469896733055	[155]	[30,13,42]	-7	hSpCas9	negative selection	1613523
40272880	40272903	15	+	26627737	HeLa	viability after 15 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.40656396449859056	[849]	[650,318,398]	3	hSpCas9	negative selection	1613524
40274214	40274237	15	-	26627737	HeLa	viability after 15 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	-0.3714399653195004	[129]	[0,35,89]	-3	hSpCas9	negative selection	1613525
40276061	40276084	15	-	26627737	HeLa	viability after 15 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.8818049554539238	[468]	[38,128,146]	-6	hSpCas9	negative selection	1613526
40264947	40264970	15	+	26627737	HeLa	viability after 18 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.8910490694558023	[328]	[32,50,108]	-7	hSpCas9	negative selection	1695836
40266064	40266087	15	+	26627737	HeLa	viability after 18 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-1.5586918661178157	[2341]	[139,250,471]	-8	hSpCas9	negative selection	1695837
40272574	40272597	15	-	26627737	HeLa	viability after 18 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	-1.0733194541811995	[155]	[21,12,42]	-7	hSpCas9	negative selection	1695838
40272880	40272903	15	+	26627737	HeLa	viability after 18 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.43012088136275195	[849]	[453,260,398]	3	hSpCas9	negative selection	1695839
40274214	40274237	15	-	26627737	HeLa	viability after 18 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	-0.33418133495218183	[129]	[0,31,89]	-3	hSpCas9	negative selection	1695840
40276061	40276084	15	-	26627737	HeLa	viability after 18 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.876232268573408	[468]	[21,112,146]	-6	hSpCas9	negative selection	1695841
40264947	40264970	15	+	26627737	HCT116	viability after 6 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-2.4103318147877197	[712]	[42,8]	-8	hSpCas9	negative selection	1778151
40266064	40266087	15	+	26627737	HCT116	viability after 6 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.9767582236216446	[2298]	[454,33]	-5	hSpCas9	negative selection	1778152
40272574	40272597	15	-	26627737	HCT116	viability after 6 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	2.2821499909444016	[168]	[96,146]	9	hSpCas9	negative selection	1778153
40272880	40272903	15	+	26627737	HCT116	viability after 6 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	1.0184479618556805	[2053]	[880,528]	5	hSpCas9	negative selection	1778154
40274214	40274237	15	-	26627737	HCT116	viability after 6 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	-1.4975825618962784	[276]	[17,13]	-7	hSpCas9	negative selection	1778155
40276061	40276084	15	-	26627737	HCT116	viability after 6 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	1.390503253477063	[661]	[141,344]	7	hSpCas9	negative selection	1778156
40264947	40264970	15	+	26627737	HCT116	viability after 8 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.237688301732214	[185]	[101,68,89]	-3	hSpCas9	negative selection	1860466
40266064	40266087	15	+	26627737	HCT116	viability after 8 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.7233307244107057	[1386]	[565,394,429]	-7	hSpCas9	negative selection	1860467
40272574	40272597	15	-	26627737	HCT116	viability after 8 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	-1.8618891261189554	[276]	[9,39,74]	-9	hSpCas9	negative selection	1860468
40272880	40272903	15	+	26627737	HCT116	viability after 8 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.003159359220940239	[914]	[435,563,507]	0	hSpCas9	negative selection	1860469
40274214	40274237	15	-	26627737	HCT116	viability after 8 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.2981687340460235	[104]	[45,97,68]	3	hSpCas9	negative selection	1860470
40276061	40276084	15	-	26627737	HCT116	viability after 8 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.38600738210682084	[353]	[174,183,89]	-4	hSpCas9	negative selection	1860471
40264947	40264970	15	+	26627737	HCT116	viability after 9 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.2976506398035639	[712]	[112,187]	-2	hSpCas9	negative selection	1942781
40266064	40266087	15	+	26627737	HCT116	viability after 9 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.5034276486955549	[2298]	[217,602]	-4	hSpCas9	negative selection	1942782
40272574	40272597	15	-	26627737	HCT116	viability after 9 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.9946631603252004	[168]	[42,126]	7	hSpCas9	negative selection	1942783
40272880	40272903	15	+	26627737	HCT116	viability after 9 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.4747746800713948	[2053]	[1036,544]	3	hSpCas9	negative selection	1942784
40274214	40274237	15	-	26627737	HCT116	viability after 9 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.7173966955221984	[276]	[48,178]	5	hSpCas9	negative selection	1942785
40276061	40276084	15	-	26627737	HCT116	viability after 9 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	0.47797879781663516	[661]	[291,209]	3	hSpCas9	negative selection	1942786
40264947	40264970	15	+	26627737	HCT116	viability after 12 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	0.29505263588774283	[185]	[191,100,59]	3	hSpCas9	negative selection	2025096
40266064	40266087	15	+	26627737	HCT116	viability after 12 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.5032221339865897	[1386]	[534,432,570]	-5	hSpCas9	negative selection	2025097
40272574	40272597	15	-	26627737	HCT116	viability after 12 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	-0.7518532457561597	[276]	[108,112,35]	-7	hSpCas9	negative selection	2025098
40272880	40272903	15	+	26627737	HCT116	viability after 12 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.20496552288251735	[914]	[667,644,341]	2	hSpCas9	negative selection	2025099
40274214	40274237	15	-	26627737	HCT116	viability after 12 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.9119207750357277	[104]	[71,133,108]	7	hSpCas9	negative selection	2025100
40276061	40276084	15	-	26627737	HCT116	viability after 12 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.41721069965039936	[353]	[86,157,177]	-4	hSpCas9	negative selection	2025101
40264947	40264970	15	+	26627737	HCT116	viability after 15 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	0.06816241513719434	[185]	[199,61,84]	0	hSpCas9	negative selection	2107411
40266064	40266087	15	+	26627737	HCT116	viability after 15 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.5357722378472394	[1386]	[526,434,681]	-5	hSpCas9	negative selection	2107412
40272574	40272597	15	-	26627737	HCT116	viability after 15 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	-0.7396346969892336	[276]	[109,114,62]	-6	hSpCas9	negative selection	2107413
40272880	40272903	15	+	26627737	HCT116	viability after 15 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.1150652775908565	[914]	[539,778,386]	1	hSpCas9	negative selection	2107414
40274214	40274237	15	-	26627737	HCT116	viability after 15 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	1.0237702587687547	[104]	[50,259,48]	8	hSpCas9	negative selection	2107415
40276061	40276084	15	-	26627737	HCT116	viability after 15 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.5055242308393503	[353]	[177,124,130]	-5	hSpCas9	negative selection	2107416
40264947	40264970	15	+	26627737	HCT116	viability after 18 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	0.5063962815155431	[185]	[139,132,108]	4	hSpCas9	negative selection	2189726
40266064	40266087	15	+	26627737	HCT116	viability after 18 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.654921351480777	[1386]	[349,487,435]	-5	hSpCas9	negative selection	2189727
40272574	40272597	15	-	26627737	HCT116	viability after 18 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	-0.3539569174041216	[276]	[141,100,69]	-3	hSpCas9	negative selection	2189728
40272880	40272903	15	+	26627737	HCT116	viability after 18 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.14327894312438705	[914]	[433,524,504]	1	hSpCas9	negative selection	2189729
40274214	40274237	15	-	26627737	HCT116	viability after 18 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.2081551752514894	[104]	[22,123,22]	1	hSpCas9	negative selection	2189730
40276061	40276084	15	-	26627737	HCT116	viability after 18 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.7264921381277496	[353]	[153,50,108]	-6	hSpCas9	negative selection	2189731
40264812	40264835	15	-	24336569	HL60	viability	TCTGTGGCGCTGAGATCTCAGGG	PAK6	ENSG00000137843	0.27399988784145024	[994]	[2545]	2	hSpCas9	negative selection	2282532
40264828	40264851	15	-	24336569	HL60	viability	ACACGGTGCTGGAAGTTCTGTGG	PAK6	ENSG00000137843	0.48695209121237704	[379]	[1126]	4	hSpCas9	negative selection	2282533
40264839	40264862	15	-	24336569	HL60	viability	AGGAGGTGTGGACACGGTGCTGG	PAK6	ENSG00000137843	0.19346822542248354	[1116]	[2702]	2	hSpCas9	negative selection	2282534
40264845	40264868	15	-	24336569	HL60	viability	GGTCGAAGGAGGTGTGGACACGG	PAK6	ENSG00000137843	-0.5468751224228594	[951]	[1378]	-5	hSpCas9	negative selection	2282535
40264867	40264890	15	+	24336569	HL60	viability	CCCAAAGAAGGCAAGTTTGTGGG	PAK6	ENSG00000137843	0.10703300684983785	[848]	[1934]	1	hSpCas9	negative selection	2282536
40264896	40264919	15	-	24336569	HL60	viability	CCAGGATGTTCTGCCATTGTGGG	PAK6	ENSG00000137843	-0.3907652611008561	[1748]	[2822]	-3	hSpCas9	negative selection	2282537
40264907	40264930	15	+	24336569	HL60	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.11883454985693498	[1409]	[3239]	1	hSpCas9	negative selection	2282538
40264933	40264956	15	-	24336569	HL60	viability	GAAGGGTCCACCACGGGCTTGGG	PAK6	ENSG00000137843	0.09934921695615229	[351]	[797]	1	hSpCas9	negative selection	2282539
40264939	40264962	15	-	24336569	HL60	viability	ATTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	1.3486627347728875	[320]	[1729]	8	hSpCas9	negative selection	2282540
40264946	40264969	15	+	24336569	HL60	viability	TGGACCCTTCGCGAATCACACGG	PAK6	ENSG00000137843	1.2327637355768841	[262]	[1307]	8	hSpCas9	negative selection	2282541
40264812	40264835	15	-	24336569	KBM7	viability	TCTGTGGCGCTGAGATCTCAGGG	PAK6	ENSG00000137843	0.06772819300446109	[883]	[2526]	0	hSpCas9	negative selection	2349709
40264828	40264851	15	-	24336569	KBM7	viability	ACACGGTGCTGGAAGTTCTGTGG	PAK6	ENSG00000137843	0.9586438282550962	[235]	[1250]	8	hSpCas9	negative selection	2349710
40264839	40264862	15	-	24336569	KBM7	viability	AGGAGGTGTGGACACGGTGCTGG	PAK6	ENSG00000137843	0.38092350037491984	[831]	[2954]	3	hSpCas9	negative selection	2349711
40264845	40264868	15	-	24336569	KBM7	viability	GGTCGAAGGAGGTGTGGACACGG	PAK6	ENSG00000137843	0.8239309913522564	[692]	[3345]	7	hSpCas9	negative selection	2349712
40264867	40264890	15	+	24336569	KBM7	viability	CCCAAAGAAGGCAAGTTTGTGGG	PAK6	ENSG00000137843	0.6629959997940483	[702]	[3035]	6	hSpCas9	negative selection	2349713
40264896	40264919	15	-	24336569	KBM7	viability	CCAGGATGTTCTGCCATTGTGGG	PAK6	ENSG00000137843	0.39888954684794364	[1101]	[3962]	3	hSpCas9	negative selection	2349714
40264907	40264930	15	+	24336569	KBM7	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.22435448263573776	[1265]	[4033]	2	hSpCas9	negative selection	2349715
40264933	40264956	15	-	24336569	KBM7	viability	GAAGGGTCCACCACGGGCTTGGG	PAK6	ENSG00000137843	-0.037221218209908834	[385]	[1025]	0	hSpCas9	negative selection	2349716
40264939	40264962	15	-	24336569	KBM7	viability	ATTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.8866797002491992	[232]	[1174]	7	hSpCas9	negative selection	2349717
40264946	40264969	15	+	24336569	KBM7	viability	TGGACCCTTCGCGAATCACACGG	PAK6	ENSG00000137843	0.26013259264220945	[273]	[894]	2	hSpCas9	negative selection	2349718
40253003	40253026	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGGGCTTACGGGGAGAAGGGG	PAK6	ENSG00000137843	0.17071232534565484	[60,140]	[4,45]	0	dCas9-VP64	positive selection	2391914
40252977	40253000	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGGGCGCAGCACCGCTTCCGGG	PAK6	ENSG00000137843	-0.07517159309861099	[100,294]	[20,63]	0	dCas9-VP64	positive selection	2391915
40253012	40253035	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCTCCTTGCGGGGCTTACGGG	PAK6	ENSG00000137843	0.3807101319260019	[21,40]	[2,14]	1	dCas9-VP64	positive selection	2419302
40253054	40253077	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCGCCTCCCGACTGAACTCCTGG	PAK6	ENSG00000137843	-2.404202700674818	[667,254]	[14,21]	-9	dCas9-VP64	positive selection	2419303
40252978	40253001	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTTGGGCGCAGCACCGCTTCCGG	PAK6	ENSG00000137843	0.5251421988243765	[200,244]	[28,115]	2	dCas9-VP64	positive selection	2419304
40238976	40238999	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGAATTTACAAATCAGCTGG	PAK6	ENSG00000137843	1.3502503880763683	[127,63]	[88,14]	5	dCas9-VP64	positive selection	2419305
40238897	40238920	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGAGGAAGGGCTGCCTGCCGG	PAK6	ENSG00000137843	1.0136071592314182	[58,303]	[13,154]	4	dCas9-VP64	positive selection	2419306
40238924	40238947	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TATCTGCCTTTCTTTGCTGAAGG	PAK6	ENSG00000137843	1.650707298411671	[181,1207]	[56,950]	6	dCas9-VP64	positive selection	2419307
40221621	40221644	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCTCAGCACTTTGGGCAG	PAK6	ENSG00000259288	0.15607651136927458	[32,6]	[6,1]	0	dCas9-VP64	positive selection	2438137
40219674	40219697	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGCCACTGCACTCCACCCAGG	PAK6	ENSG00000259288	1.8834074276407538	[71,51]	[70,27]	6	dCas9-VP64	positive selection	2443947
40239597	40239620	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAATAGCAGATATGGTGGTCAGG	PAK6	ENSG00000137843	-0.4053973770956426	[240,13]	[28,11]	-2	dCas9-VP64	positive selection	2451374
40239675	40239698	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGACTGGAGTCCTCCCGGGCTGG	PAK6	ENSG00000137843	-0.010227460092052887	[16,0]	[1,1]	0	dCas9-VP64	positive selection	2451375
40239634	40239657	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCTGTCCCAACACCTCCAGAGG	PAK6	ENSG00000137843	-1.5069724994359666	[462,268]	[28,25]	-8	dCas9-VP64	positive selection	2451376
40244596	40244619	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACTAGCCTGGCCAACATAG	PAK6	ENSG00000137843	0.3601150748164519	[269,268]	[95,53]	1	dCas9-VP64	positive selection	2458896
40227965	40227988	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCCGCCTTCTAG	PAK6	ENSG00000259288	0.2792775090634416	[552,542]	[69,227]	1	dCas9-VP64	positive selection	2464312
40227966	40227989	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCGCCTTCTAGG	PAK6	ENSG00000259288	-1.1299099924366551	[152,73]	[14,5]	-6	dCas9-VP64	positive selection	2465411
40261436	40261459	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCAAGTGATTCTCCTGCCTTAG	PAK6	ENSG00000137843	0.04005304646372276	[213,38]	[51,1]	0	dCas9-VP64	positive selection	2477987
40253003	40253026	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGGGCTTACGGGGAGAAGGGG	PAK6	ENSG00000137843	-0.7030264122669024	[60,77]	[9,16]	-6	dCas9-VP64	positive selection	2487169
40252977	40253000	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGGGCGCAGCACCGCTTCCGGG	PAK6	ENSG00000137843	1.2809342643230235	[36,159]	[120,35]	7	dCas9-VP64	positive selection	2487170
40253012	40253035	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCTCCTTGCGGGGCTTACGGG	PAK6	ENSG00000137843	-0.6002585865894875	[20,124]	[16,12]	-6	dCas9-VP64	positive selection	2514557
40253054	40253077	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCGCCTCCCGACTGAACTCCTGG	PAK6	ENSG00000137843	-0.6575244415566024	[367,442]	[58,105]	-6	dCas9-VP64	positive selection	2514558
40252978	40253001	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTTGGGCGCAGCACCGCTTCCGG	PAK6	ENSG00000137843	-0.2103878454798046	[120,54]	[14,33]	-2	dCas9-VP64	positive selection	2514559
40238976	40238999	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGAATTTACAAATCAGCTGG	PAK6	ENSG00000137843	-0.7788766464129051	[538,131]	[106,24]	-7	dCas9-VP64	positive selection	2514560
40238897	40238920	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGAGGAAGGGCTGCCTGCCGG	PAK6	ENSG00000137843	0.07692390856716025	[114,34]	[36,15]	0	dCas9-VP64	positive selection	2514561
40238924	40238947	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TATCTGCCTTTCTTTGCTGAAGG	PAK6	ENSG00000137843	-0.39698394064284914	[254,340]	[66,79]	-4	dCas9-VP64	positive selection	2514562
40221621	40221644	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCTCAGCACTTTGGGCAG	PAK6	ENSG00000259288	-0.09854114350347812	[128,153]	[28,55]	-1	dCas9-VP64	positive selection	2533392
40219674	40219697	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGCCACTGCACTCCACCCAGG	PAK6	ENSG00000259288	-0.10769466573443187	[156,168]	[45,51]	-1	dCas9-VP64	positive selection	2539202
40239597	40239620	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAATAGCAGATATGGTGGTCAGG	PAK6	ENSG00000137843	-1.6879234564527814	[154,226]	[23,13]	-9	dCas9-VP64	positive selection	2546629
40239675	40239698	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGACTGGAGTCCTCCCGGGCTGG	PAK6	ENSG00000137843	-0.40137699530474147	[70,45]	[16,10]	-4	dCas9-VP64	positive selection	2546630
40239634	40239657	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCTGTCCCAACACCTCCAGAGG	PAK6	ENSG00000137843	2.2972475114785715	[199,200]	[60,567]	8	dCas9-VP64	positive selection	2546631
40244596	40244619	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACTAGCCTGGCCAACATAG	PAK6	ENSG00000137843	-0.8374586120276372	[108,300]	[27,44]	-7	dCas9-VP64	positive selection	2554151
40227965	40227988	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCCGCCTTCTAG	PAK6	ENSG00000259288	0.2904267335704165	[840,610]	[251,326]	2	dCas9-VP64	positive selection	2559567
40227966	40227989	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCGCCTTCTAGG	PAK6	ENSG00000259288	1.9293870201515944	[173,114]	[70,283]	8	dCas9-VP64	positive selection	2560666
40261436	40261459	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCAAGTGATTCTCCTGCCTTAG	PAK6	ENSG00000137843	-0.7043264998708204	[149,257]	[17,60]	-6	dCas9-VP64	positive selection	2573242
40264933	40264956	15	-	27260157	DLD1	viability	GAAGGGTCCACCACGGGCTTGGG	PAK6	ENSG00000137843	0.448766897395207	[]	[]	7	hSpCas9	negative selection	2574705
40264907	40264930	15	+	27260157	DLD1	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.537538541935404	[]	[]	8	hSpCas9	negative selection	2576564
40266005	40266028	15	-	27260157	DLD1	viability	GAGGTACATGTCTGGGTCGGTGG	PAK6	ENSG00000137843	-0.884982280487081	[]	[]	-6	hSpCas9	negative selection	2578500
40266054	40266077	15	-	27260157	DLD1	viability	AGCTGAGGTAGAGGCCGTGGGGG	PAK6	ENSG00000137843	-0.318059854803843	[]	[]	-3	hSpCas9	negative selection	2579615
40265920	40265943	15	+	27260157	DLD1	viability	ATCAGCTCCAACACCCTGCGTGG	PAK6	ENSG00000137843	0.274840064659333	[]	[]	4	hSpCas9	negative selection	2581991
40264828	40264851	15	-	27260157	DLD1	viability	ACACGGTGCTGGAAGTTCTGTGG	PAK6	ENSG00000137843	-0.402209457859207	[]	[]	-3	hSpCas9	negative selection	2584898
40264867	40264890	15	+	27260157	DLD1	viability	CCCAAAGAAGGCAAGTTTGTGGG	PAK6	ENSG00000137843	0.738558604045793	[]	[]	8	hSpCas9	negative selection	2586338
40264946	40264969	15	+	27260157	DLD1	viability	TGGACCCTTCGCGAATCACACGG	PAK6	ENSG00000137843	0.326467579471488	[]	[]	4	hSpCas9	negative selection	2606647
40266112	40266135	15	-	27260157	DLD1	viability	GGGCTCTGTGGCTCGGGCCACGG	PAK6	ENSG00000137843	-0.547591855599319	[]	[]	-4	hSpCas9	negative selection	2607307
40264939	40264962	15	-	27260157	DLD1	viability	ATTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.703272237912779	[]	[]	8	hSpCas9	negative selection	2607579
40264950	40264973	15	-	27260157	DLD1	viability	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	-0.568406897824604	[]	[]	-4	hSpCas9	negative selection	2618988
40264845	40264868	15	-	27260157	DLD1	viability	GGTCGAAGGAGGTGTGGACACGG	PAK6	ENSG00000137843	-1.14440651448217	[]	[]	-7	hSpCas9	negative selection	2619689
40265927	40265950	15	-	27260157	DLD1	viability	GCTGCGGCCACGCAGGGTGTTGG	PAK6	ENSG00000137843	-0.659193870268156	[]	[]	-5	hSpCas9	negative selection	2621386
40266272	40266295	15	-	27260157	DLD1	viability	AGCCTTCATTCCATGCCTATTGG	PAK6	ENSG00000137843	0.363855106714091	[]	[]	4	hSpCas9	negative selection	2622029
40264932	40264955	15	-	27260157	DLD1	viability	AAGGGTCCACCACGGGCTTGGGG	PAK6	ENSG00000137843	0.192785961563517	[]	[]	3	hSpCas9	negative selection	2622698
40264812	40264835	15	-	27260157	DLD1	viability	TCTGTGGCGCTGAGATCTCAGGG	PAK6	ENSG00000137843	0.244373862625924	[]	[]	4	hSpCas9	negative selection	2642757
40264839	40264862	15	-	27260157	DLD1	viability	AGGAGGTGTGGACACGGTGCTGG	PAK6	ENSG00000137843	-0.303010162206085	[]	[]	-2	hSpCas9	negative selection	2644642
40264896	40264919	15	-	27260157	DLD1	viability	CCAGGATGTTCTGCCATTGTGGG	PAK6	ENSG00000137843	-0.221430581495336	[]	[]	-2	hSpCas9	negative selection	2647890
40264933	40264956	15	-	27260157	HT1080	viability	GAAGGGTCCACCACGGGCTTGGG	PAK6	ENSG00000137843	0.322128713340583	[]	[]	3	hSpCas9	negative selection	2650835
40264907	40264930	15	+	27260157	HT1080	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.813039035614467	[]	[]	7	hSpCas9	negative selection	2652694
40266005	40266028	15	-	27260157	HT1080	viability	GAGGTACATGTCTGGGTCGGTGG	PAK6	ENSG00000137843	-0.663093248635199	[]	[]	-8	hSpCas9	negative selection	2654630
40266054	40266077	15	-	27260157	HT1080	viability	AGCTGAGGTAGAGGCCGTGGGGG	PAK6	ENSG00000137843	-0.2805476171235	[]	[]	-4	hSpCas9	negative selection	2655745
40265920	40265943	15	+	27260157	HT1080	viability	ATCAGCTCCAACACCCTGCGTGG	PAK6	ENSG00000137843	0.605766345943281	[]	[]	5	hSpCas9	negative selection	2658121
40264828	40264851	15	-	27260157	HT1080	viability	ACACGGTGCTGGAAGTTCTGTGG	PAK6	ENSG00000137843	0.710893480133296	[]	[]	6	hSpCas9	negative selection	2661028
40264867	40264890	15	+	27260157	HT1080	viability	CCCAAAGAAGGCAAGTTTGTGGG	PAK6	ENSG00000137843	0.690368557545631	[]	[]	6	hSpCas9	negative selection	2662468
40264946	40264969	15	+	27260157	HT1080	viability	TGGACCCTTCGCGAATCACACGG	PAK6	ENSG00000137843	0.427130337096823	[]	[]	4	hSpCas9	negative selection	2682777
40266112	40266135	15	-	27260157	HT1080	viability	GGGCTCTGTGGCTCGGGCCACGG	PAK6	ENSG00000137843	0.683606502123693	[]	[]	6	hSpCas9	negative selection	2683437
40264939	40264962	15	-	27260157	HT1080	viability	ATTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.739572274332721	[]	[]	6	hSpCas9	negative selection	2683709
40264950	40264973	15	-	27260157	HT1080	viability	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	-1.09030369601254	[]	[]	-8	hSpCas9	negative selection	2695118
40264845	40264868	15	-	27260157	HT1080	viability	GGTCGAAGGAGGTGTGGACACGG	PAK6	ENSG00000137843	-0.928603783832915	[]	[]	-8	hSpCas9	negative selection	2695819
40265927	40265950	15	-	27260157	HT1080	viability	GCTGCGGCCACGCAGGGTGTTGG	PAK6	ENSG00000137843	0.0451172471519816	[]	[]	0	hSpCas9	negative selection	2697516
40266272	40266295	15	-	27260157	HT1080	viability	AGCCTTCATTCCATGCCTATTGG	PAK6	ENSG00000137843	0.986553380994521	[]	[]	8	hSpCas9	negative selection	2698159
40264932	40264955	15	-	27260157	HT1080	viability	AAGGGTCCACCACGGGCTTGGGG	PAK6	ENSG00000137843	0.553637628591808	[]	[]	5	hSpCas9	negative selection	2698828
40264812	40264835	15	-	27260157	HT1080	viability	TCTGTGGCGCTGAGATCTCAGGG	PAK6	ENSG00000137843	-0.711454060464523	[]	[]	-8	hSpCas9	negative selection	2718887
40264839	40264862	15	-	27260157	HT1080	viability	AGGAGGTGTGGACACGGTGCTGG	PAK6	ENSG00000137843	-1.17279260459038	[]	[]	-8	hSpCas9	negative selection	2720772
40264896	40264919	15	-	27260157	HT1080	viability	CCAGGATGTTCTGCCATTGTGGG	PAK6	ENSG00000137843	0.525494220707514	[]	[]	4	hSpCas9	negative selection	2724020
40264933	40264956	15	-	27260157	MKN45	viability	GAAGGGTCCACCACGGGCTTGGG	PAK6	ENSG00000137843	0.241520404997301	[]	[]	5	hSpCas9	negative selection	2726965
40264907	40264930	15	+	27260157	MKN45	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.30160967593299	[]	[]	5	hSpCas9	negative selection	2728824
40266005	40266028	15	-	27260157	MKN45	viability	GAGGTACATGTCTGGGTCGGTGG	PAK6	ENSG00000137843	-1.22453926080543	[]	[]	-8	hSpCas9	negative selection	2730760
40266054	40266077	15	-	27260157	MKN45	viability	AGCTGAGGTAGAGGCCGTGGGGG	PAK6	ENSG00000137843	-1.03496431574334	[]	[]	-8	hSpCas9	negative selection	2731875
40265920	40265943	15	+	27260157	MKN45	viability	ATCAGCTCCAACACCCTGCGTGG	PAK6	ENSG00000137843	0.625062175355054	[]	[]	7	hSpCas9	negative selection	2734251
40264828	40264851	15	-	27260157	MKN45	viability	ACACGGTGCTGGAAGTTCTGTGG	PAK6	ENSG00000137843	0.0421983370356595	[]	[]	0	hSpCas9	negative selection	2737158
40264867	40264890	15	+	27260157	MKN45	viability	CCCAAAGAAGGCAAGTTTGTGGG	PAK6	ENSG00000137843	0.934442443637157	[]	[]	8	hSpCas9	negative selection	2738598
40264946	40264969	15	+	27260157	MKN45	viability	TGGACCCTTCGCGAATCACACGG	PAK6	ENSG00000137843	-0.0637614622833515	[]	[]	0	hSpCas9	negative selection	2758907
40266112	40266135	15	-	27260157	MKN45	viability	GGGCTCTGTGGCTCGGGCCACGG	PAK6	ENSG00000137843	0.0893522629059604	[]	[]	0	hSpCas9	negative selection	2759567
40264939	40264962	15	-	27260157	MKN45	viability	ATTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	-0.270138341423032	[]	[]	-1	hSpCas9	negative selection	2759839
40264950	40264973	15	-	27260157	MKN45	viability	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	-1.50610487717833	[]	[]	-8	hSpCas9	negative selection	2771248
40264845	40264868	15	-	27260157	MKN45	viability	GGTCGAAGGAGGTGTGGACACGG	PAK6	ENSG00000137843	-0.701769057555662	[]	[]	-7	hSpCas9	negative selection	2771949
40265927	40265950	15	-	27260157	MKN45	viability	GCTGCGGCCACGCAGGGTGTTGG	PAK6	ENSG00000137843	-1.14781859181573	[]	[]	-8	hSpCas9	negative selection	2773646
40266272	40266295	15	-	27260157	MKN45	viability	AGCCTTCATTCCATGCCTATTGG	PAK6	ENSG00000137843	0.858513743989443	[]	[]	8	hSpCas9	negative selection	2774289
40264932	40264955	15	-	27260157	MKN45	viability	AAGGGTCCACCACGGGCTTGGGG	PAK6	ENSG00000137843	0.62843353673418	[]	[]	7	hSpCas9	negative selection	2774958
40264812	40264835	15	-	27260157	MKN45	viability	TCTGTGGCGCTGAGATCTCAGGG	PAK6	ENSG00000137843	-0.771234157820998	[]	[]	-7	hSpCas9	negative selection	2795017
40264839	40264862	15	-	27260157	MKN45	viability	AGGAGGTGTGGACACGGTGCTGG	PAK6	ENSG00000137843	0.236327609505194	[]	[]	5	hSpCas9	negative selection	2796902
40264896	40264919	15	-	27260157	MKN45	viability	CCAGGATGTTCTGCCATTGTGGG	PAK6	ENSG00000137843	1.03515490432023	[]	[]	8	hSpCas9	negative selection	2800150
40264933	40264956	15	-	27260157	RKO	viability	GAAGGGTCCACCACGGGCTTGGG	PAK6	ENSG00000137843	0.345313296558708	[]	[]	1	hSpCas9	negative selection	2803095
40264907	40264930	15	+	27260157	RKO	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.463826413560866	[]	[]	2	hSpCas9	negative selection	2804954
40266005	40266028	15	-	27260157	RKO	viability	GAGGTACATGTCTGGGTCGGTGG	PAK6	ENSG00000137843	-1.01008853587684	[]	[]	-8	hSpCas9	negative selection	2806890
40266054	40266077	15	-	27260157	RKO	viability	AGCTGAGGTAGAGGCCGTGGGGG	PAK6	ENSG00000137843	-0.908584121655288	[]	[]	-8	hSpCas9	negative selection	2808005
40265920	40265943	15	+	27260157	RKO	viability	ATCAGCTCCAACACCCTGCGTGG	PAK6	ENSG00000137843	0.768188287129878	[]	[]	8	hSpCas9	negative selection	2810381
40264828	40264851	15	-	27260157	RKO	viability	ACACGGTGCTGGAAGTTCTGTGG	PAK6	ENSG00000137843	0.439650125616619	[]	[]	2	hSpCas9	negative selection	2813288
40264867	40264890	15	+	27260157	RKO	viability	CCCAAAGAAGGCAAGTTTGTGGG	PAK6	ENSG00000137843	0.439367917543473	[]	[]	2	hSpCas9	negative selection	2814728
40264946	40264969	15	+	27260157	RKO	viability	TGGACCCTTCGCGAATCACACGG	PAK6	ENSG00000137843	-0.517830579521527	[]	[]	-6	hSpCas9	negative selection	2835037
40266112	40266135	15	-	27260157	RKO	viability	GGGCTCTGTGGCTCGGGCCACGG	PAK6	ENSG00000137843	0.810760493727255	[]	[]	8	hSpCas9	negative selection	2835697
40264939	40264962	15	-	27260157	RKO	viability	ATTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.0290850921221944	[]	[]	0	hSpCas9	negative selection	2835969
40264950	40264973	15	-	27260157	RKO	viability	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	0.0409667446578991	[]	[]	0	hSpCas9	negative selection	2847378
40264845	40264868	15	-	27260157	RKO	viability	GGTCGAAGGAGGTGTGGACACGG	PAK6	ENSG00000137843	-0.0867722468683089	[]	[]	0	hSpCas9	negative selection	2848079
40265927	40265950	15	-	27260157	RKO	viability	GCTGCGGCCACGCAGGGTGTTGG	PAK6	ENSG00000137843	-1.00802882181847	[]	[]	-8	hSpCas9	negative selection	2849776
40266272	40266295	15	-	27260157	RKO	viability	AGCCTTCATTCCATGCCTATTGG	PAK6	ENSG00000137843	0.705977196274923	[]	[]	8	hSpCas9	negative selection	2850419
40264932	40264955	15	-	27260157	RKO	viability	AAGGGTCCACCACGGGCTTGGGG	PAK6	ENSG00000137843	0.520957464887131	[]	[]	2	hSpCas9	negative selection	2851088
40264812	40264835	15	-	27260157	RKO	viability	TCTGTGGCGCTGAGATCTCAGGG	PAK6	ENSG00000137843	0.339920710846186	[]	[]	1	hSpCas9	negative selection	2871147
40264839	40264862	15	-	27260157	RKO	viability	AGGAGGTGTGGACACGGTGCTGG	PAK6	ENSG00000137843	-0.330824138316647	[]	[]	-6	hSpCas9	negative selection	2873032
40264896	40264919	15	-	27260157	RKO	viability	CCAGGATGTTCTGCCATTGTGGG	PAK6	ENSG00000137843	-0.235228582170567	[]	[]	-1	hSpCas9	negative selection	2876280
40264933	40264956	15	-	27260157	SF268	viability	GAAGGGTCCACCACGGGCTTGGG	PAK6	ENSG00000137843	1.1890603472361	[]	[]	9	hSpCas9	negative selection	2879225
40264907	40264930	15	+	27260157	SF268	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.457194903971121	[]	[]	7	hSpCas9	negative selection	2881084
40266005	40266028	15	-	27260157	SF268	viability	GAGGTACATGTCTGGGTCGGTGG	PAK6	ENSG00000137843	-0.852201928971739	[]	[]	-6	hSpCas9	negative selection	2883020
40266054	40266077	15	-	27260157	SF268	viability	AGCTGAGGTAGAGGCCGTGGGGG	PAK6	ENSG00000137843	-0.481030582807767	[]	[]	-4	hSpCas9	negative selection	2884135
40265920	40265943	15	+	27260157	SF268	viability	ATCAGCTCCAACACCCTGCGTGG	PAK6	ENSG00000137843	-0.430087753069691	[]	[]	-3	hSpCas9	negative selection	2886511
40264828	40264851	15	-	27260157	SF268	viability	ACACGGTGCTGGAAGTTCTGTGG	PAK6	ENSG00000137843	-0.15935158715946	[]	[]	-1	hSpCas9	negative selection	2889418
40264867	40264890	15	+	27260157	SF268	viability	CCCAAAGAAGGCAAGTTTGTGGG	PAK6	ENSG00000137843	0.257881025155184	[]	[]	4	hSpCas9	negative selection	2890858
40264946	40264969	15	+	27260157	SF268	viability	TGGACCCTTCGCGAATCACACGG	PAK6	ENSG00000137843	-0.657172755144659	[]	[]	-5	hSpCas9	negative selection	2911167
40266112	40266135	15	-	27260157	SF268	viability	GGGCTCTGTGGCTCGGGCCACGG	PAK6	ENSG00000137843	0.506958578611971	[]	[]	7	hSpCas9	negative selection	2911827
40264939	40264962	15	-	27260157	SF268	viability	ATTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	-0.458952936543051	[]	[]	-4	hSpCas9	negative selection	2912099
40264950	40264973	15	-	27260157	SF268	viability	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	-0.518461478857709	[]	[]	-4	hSpCas9	negative selection	2923508
40264845	40264868	15	-	27260157	SF268	viability	GGTCGAAGGAGGTGTGGACACGG	PAK6	ENSG00000137843	-0.985711715934604	[]	[]	-7	hSpCas9	negative selection	2924209
40265927	40265950	15	-	27260157	SF268	viability	GCTGCGGCCACGCAGGGTGTTGG	PAK6	ENSG00000137843	-0.297352585847975	[]	[]	-2	hSpCas9	negative selection	2925906
40266272	40266295	15	-	27260157	SF268	viability	AGCCTTCATTCCATGCCTATTGG	PAK6	ENSG00000137843	1.05533608598053	[]	[]	9	hSpCas9	negative selection	2926549
40264932	40264955	15	-	27260157	SF268	viability	AAGGGTCCACCACGGGCTTGGGG	PAK6	ENSG00000137843	0.098286781922762	[]	[]	0	hSpCas9	negative selection	2927218
40264812	40264835	15	-	27260157	SF268	viability	TCTGTGGCGCTGAGATCTCAGGG	PAK6	ENSG00000137843	-0.16649998632178	[]	[]	-1	hSpCas9	negative selection	2947277
40264839	40264862	15	-	27260157	SF268	viability	AGGAGGTGTGGACACGGTGCTGG	PAK6	ENSG00000137843	0.359527841644368	[]	[]	4	hSpCas9	negative selection	2949162
40264896	40264919	15	-	27260157	SF268	viability	CCAGGATGTTCTGCCATTGTGGG	PAK6	ENSG00000137843	-0.194207650388679	[]	[]	-1	hSpCas9	negative selection	2952410
40253219	40253242	15	+	27013184	SW480	treatment with recombinant TRAIL	CTCCTCAGCGCCTAAGAGAGAGG	PAK6	ENSG00000137843	-1.6283674494491645	[135,148]	[25,10]	-6	hSpCas9	positive selection	2960526
40253245	40253268	15	+	27013184	SW480	treatment with recombinant TRAIL	AGTGCGGGTGAGGAGTCGCGAGG	PAK6	ENSG00000137843	2.0074844728316648	[22,114]	[91,141]	8	hSpCas9	positive selection	2960527
40264812	40264835	15	-	27013184	SW480	treatment with recombinant TRAIL	TCTGTGGCGCTGAGATCTCAGGG	PAK6	ENSG00000137843	-1.1036638645237937	[134,91]	[23,21]	-5	hSpCas9	positive selection	2960528
40264813	40264836	15	-	27013184	SW480	treatment with recombinant TRAIL	TTCTGTGGCGCTGAGATCTCAGG	PAK6	ENSG00000137843	-0.7275766865940065	[1246,1630]	[247,544]	-3	hSpCas9	positive selection	2960529
40264828	40264851	15	-	27013184	SW480	treatment with recombinant TRAIL	ACACGGTGCTGGAAGTTCTGTGG	PAK6	ENSG00000137843	-0.01801623376605277	[320,477]	[196,124]	0	hSpCas9	positive selection	2960530
40264839	40264862	15	-	27013184	SW480	treatment with recombinant TRAIL	AGGAGGTGTGGACACGGTGCTGG	PAK6	ENSG00000137843	0.0818079210352034	[375,417]	[106,284]	0	hSpCas9	positive selection	2960531
40264856	40264879	15	-	27013184	SW480	treatment with recombinant TRAIL	GCCTTCTTTGGGGTCGAAGGAGG	PAK6	ENSG00000137843	1.1508476122580888	[1013,1288]	[1115,1056]	5	hSpCas9	positive selection	2960532
40264866	40264889	15	-	27013184	SW480	treatment with recombinant TRAIL	CCACAAACTTGCCTTCTTTGGGG	PAK6	ENSG00000137843	-0.777113007940067	[64,94]	[25,10]	-4	hSpCas9	positive selection	2960533
40264867	40264890	15	-	27013184	SW480	treatment with recombinant TRAIL	CCCACAAACTTGCCTTCTTTGGG	PAK6	ENSG00000137843	2.243887388451387	[75,132]	[200,218]	8	hSpCas9	positive selection	2960534
40264868	40264891	15	-	27013184	SW480	treatment with recombinant TRAIL	GCCCACAAACTTGCCTTCTTTGG	PAK6	ENSG00000137843	-0.2531555285537932	[121,111]	[70,1]	-1	hSpCas9	positive selection	2960535
40264894	40264917	15	-	27013184	SW480	treatment with recombinant TRAIL	AGGATGTTCTGCCATTGTGGGGG	PAK6	ENSG00000137843	1.2897855189595004	[21,27]	[35,11]	6	hSpCas9	positive selection	2960536
40264895	40264918	15	-	27013184	SW480	treatment with recombinant TRAIL	CAGGATGTTCTGCCATTGTGGGG	PAK6	ENSG00000137843	-0.6197389987513826	[29,82]	[1,33]	-3	hSpCas9	positive selection	2960537
40264896	40264919	15	-	27013184	SW480	treatment with recombinant TRAIL	CCAGGATGTTCTGCCATTGTGGG	PAK6	ENSG00000137843	-0.587811519625254	[904,821]	[255,238]	-3	hSpCas9	positive selection	2960538
40264897	40264920	15	-	27013184	SW480	treatment with recombinant TRAIL	TCCAGGATGTTCTGCCATTGTGG	PAK6	ENSG00000137843	-0.8998679029385201	[815,1291]	[164,343]	-4	hSpCas9	positive selection	2960539
40264932	40264955	15	-	27013184	SW480	treatment with recombinant TRAIL	AAGGGTCCACCACGGGCTTGGGG	PAK6	ENSG00000137843	-0.05158414452886223	[223,322]	[116,104]	0	hSpCas9	positive selection	2960540
40264933	40264956	15	-	27013184	SW480	treatment with recombinant TRAIL	GAAGGGTCCACCACGGGCTTGGG	PAK6	ENSG00000137843	-0.20406000196627583	[424,437]	[127,208]	-1	hSpCas9	positive selection	2960541
40264934	40264957	15	-	27013184	SW480	treatment with recombinant TRAIL	CGAAGGGTCCACCACGGGCTTGG	PAK6	ENSG00000137843	-2.06431938369727	[183,106]	[9,22]	-7	hSpCas9	positive selection	2960542
40264939	40264962	15	-	27013184	SW480	treatment with recombinant TRAIL	ATTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	2.1695658734918406	[14,38]	[77,10]	8	hSpCas9	positive selection	2960543
40264940	40264963	15	-	27013184	SW480	treatment with recombinant TRAIL	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	-4.452131308089897	[64,144]	[1,1]	-9	hSpCas9	positive selection	2960544
40264950	40264973	15	-	27013184	SW480	treatment with recombinant TRAIL	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	-3.8076057587230747	[120,206]	[6,1]	-9	hSpCas9	positive selection	2960545
40264951	40264974	15	-	27013184	SW480	treatment with recombinant TRAIL	TGCACCCGTGTGATTCGCGAAGG	PAK6	ENSG00000137843	-1.2975421606205453	[590,580]	[123,72]	-5	hSpCas9	positive selection	2960546
40253215	40253238	15	-	27013184	SW480	treatment with recombinant TRAIL	TCTCTTAGGCGCTGAGGAGAGGG	PAK6	ENSG00000137843	-0.7669785262811748	[276,221]	[86,30]	-3	hSpCas9	positive selection	2960547
40253216	40253239	15	-	27013184	SW480	treatment with recombinant TRAIL	CTCTCTTAGGCGCTGAGGAGAGG	PAK6	ENSG00000137843	0.20704616504953627	[124,219]	[82,84]	1	hSpCas9	positive selection	2960548
40253242	40253265	15	-	27013184	SW480	treatment with recombinant TRAIL	CGCGACTCCTCACCCGCACTGGG	PAK6	ENSG00000137843	-0.07092473233677044	[271,564]	[114,239]	0	hSpCas9	positive selection	2960549
40253243	40253266	15	-	27013184	SW480	treatment with recombinant TRAIL	TCGCGACTCCTCACCCGCACTGG	PAK6	ENSG00000137843	0.7307762203684978	[367,911]	[348,571]	3	hSpCas9	positive selection	2960550
40264855	40264878	15	+	27013184	SW480	treatment with recombinant TRAIL	ACCTCCTTCGACCCCAAAGAAGG	PAK6	ENSG00000137843	0.5698686422961956	[405,700]	[275,445]	3	hSpCas9	positive selection	2960551
40264866	40264889	15	+	27013184	SW480	treatment with recombinant TRAIL	CCCCAAAGAAGGCAAGTTTGTGG	PAK6	ENSG00000137843	1.6296817597346143	[653,520]	[824,745]	7	hSpCas9	positive selection	2960552
40264867	40264890	15	+	27013184	SW480	treatment with recombinant TRAIL	CCCAAAGAAGGCAAGTTTGTGGG	PAK6	ENSG00000137843	-0.2266193150544613	[73,139]	[25,55]	-1	hSpCas9	positive selection	2960553
40264883	40264906	15	+	27013184	SW480	treatment with recombinant TRAIL	TTGTGGGCCTCCCCCCACAATGG	PAK6	ENSG00000137843	-0.8810286192969398	[315,332]	[34,133]	-4	hSpCas9	positive selection	2960554
40264896	40264919	15	+	27013184	SW480	treatment with recombinant TRAIL	CCCACAATGGCAGAACATCCTGG	PAK6	ENSG00000137843	0.25383997720689755	[130,76]	[36,79]	1	hSpCas9	positive selection	2960555
40217526	40217549	15	+	27013184	SW480	treatment with recombinant TRAIL	CAATCAAGCTTTGAAGATAGTGG	PAK6	ENSG00000259288	-0.10883574086860603	[91,47]	[15,46]	0	hSpCas9	positive selection	2962408
40218502	40218525	15	+	27013184	SW480	treatment with recombinant TRAIL	AGGAACACCTACAGGTCTTCTGG	PAK6	ENSG00000259288	1.2124738110114626	[1,1]	[1,1]	6	hSpCas9	positive selection	2962409
40218503	40218526	15	+	27013184	SW480	treatment with recombinant TRAIL	GGAACACCTACAGGTCTTCTGGG	PAK6	ENSG00000259288	1.2124738110114626	[1,1]	[1,1]	6	hSpCas9	positive selection	2962410
40218508	40218531	15	+	27013184	SW480	treatment with recombinant TRAIL	ACCTACAGGTCTTCTGGGATGGG	PAK6	ENSG00000259288	1.2124738110114626	[1,1]	[1,1]	6	hSpCas9	positive selection	2962412
40217553	40217576	15	+	27013184	SW480	treatment with recombinant TRAIL	TTCCTACAGTGTTGACCTTAGGG	PAK6	ENSG00000259288	1.6856110517126393	[23,54]	[87,2]	7	hSpCas9	positive selection	2962419
40217562	40217585	15	+	27013184	SW480	treatment with recombinant TRAIL	TGTTGACCTTAGGGTGCAGCTGG	PAK6	ENSG00000259288	2.6561967227453938	[230,415]	[1115,489]	9	hSpCas9	positive selection	2962422
40217604	40217627	15	+	27013184	SW480	treatment with recombinant TRAIL	CTTTCGGACTGTACAGATCCTGG	PAK6	ENSG00000259288	1.7359196889915802	[71,238]	[197,233]	7	hSpCas9	positive selection	2962423
40217499	40217522	15	-	27013184	SW480	treatment with recombinant TRAIL	TGTTACAATCATAGGGATCGTGG	PAK6	ENSG00000259288	0.92559154991331	[18,86]	[28,57]	4	hSpCas9	positive selection	2962424
40217608	40217631	15	+	27013184	SW480	treatment with recombinant TRAIL	CGGACTGTACAGATCCTGGAAGG	PAK6	ENSG00000259288	0.5883511946035795	[179,207]	[122,127]	3	hSpCas9	positive selection	2962425
40217506	40217529	15	-	27013184	SW480	treatment with recombinant TRAIL	TTGTTCTTGTTACAATCATAGGG	PAK6	ENSG00000259288	-0.5896850594846524	[261,326]	[43,139]	-3	hSpCas9	positive selection	2962426
40217555	40217578	15	-	27013184	SW480	treatment with recombinant TRAIL	CACCCTAAGGTCAACACTGTAGG	PAK6	ENSG00000259288	1.6352332817851574	[55,23]	[57,51]	7	hSpCas9	positive selection	2962427
40217568	40217591	15	-	27013184	SW480	treatment with recombinant TRAIL	AAACATCCAGCTGCACCCTAAGG	PAK6	ENSG00000259288	-0.27948451567527455	[47,22]	[5,22]	-1	hSpCas9	positive selection	2962428
40217594	40217617	15	-	27013184	SW480	treatment with recombinant TRAIL	TACAGTCCGAAAGCCGCTGAGGG	PAK6	ENSG00000259288	1.8827126370387135	[281,549]	[640,645]	8	hSpCas9	positive selection	2962429
40217595	40217618	15	-	27013184	SW480	treatment with recombinant TRAIL	GTACAGTCCGAAAGCCGCTGAGG	PAK6	ENSG00000259288	-1.9679671891661918	[90,160]	[1,29]	-7	hSpCas9	positive selection	2962430
40217622	40217645	15	-	27013184	SW480	treatment with recombinant TRAIL	CCAGGATCTTTTGTCCTTCCAGG	PAK6	ENSG00000259288	1.0390072680791944	[387,505]	[205,655]	5	hSpCas9	positive selection	2962431
40217659	40217682	15	-	27013184	SW480	treatment with recombinant TRAIL	TGTTTTACACTTACCTGGTAGGG	PAK6	ENSG00000259288	-0.29803747906378975	[238,348]	[98,104]	-1	hSpCas9	positive selection	2962432
40217660	40217683	15	-	27013184	SW480	treatment with recombinant TRAIL	TTGTTTTACACTTACCTGGTAGG	PAK6	ENSG00000259288	1.3379506824422553	[168,266]	[230,235]	6	hSpCas9	positive selection	2962433
40217664	40217687	15	-	27013184	SW480	treatment with recombinant TRAIL	AGGCTTGTTTTACACTTACCTGG	PAK6	ENSG00000259288	-0.7832227586872316	[218,347]	[41,108]	-4	hSpCas9	positive selection	2962434
40217622	40217645	15	+	27013184	SW480	treatment with recombinant TRAIL	CCTGGAAGGACAAAAGATCCTGG	PAK6	ENSG00000259288	-0.8353853270467976	[274,307]	[32,122]	-4	hSpCas9	positive selection	2962435
40217646	40217669	15	+	27013184	SW480	treatment with recombinant TRAIL	TAACTGTTCTTCTCCCTACCAGG	PAK6	ENSG00000259288	0.7230245857403403	[169,127]	[33,211]	3	hSpCas9	positive selection	2962436
40266180	40266203	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGCACCCTGAAACTCGGCGGGG	PAK6	ENSG00000137843	-0.2681905621117072	[3,2]	[2,1]	-4	hSpCas9	positive selection	3009480
40266064	40266087	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCTACCTCAGCTGCAACGGGG	PAK6	ENSG00000137843	0.3683132044291112	[4,4]	[5,4]	7	hSpCas9	positive selection	3009481
40264950	40264973	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	-0.0009938905291182465	[2,2]	[2,1]	0	hSpCas9	positive selection	3009482
40264948	40264971	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	0.20342276604960874	[2,3]	[3,2]	4	hSpCas9	positive selection	3009483
40266180	40266203	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGCACCCTGAAACTCGGCGGGG	PAK6	ENSG00000137843	-0.1879361344528465	[3,3]	[3,0]	-3	hSpCas9	positive selection	3077338
40266064	40266087	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCTACCTCAGCTGCAACGGGG	PAK6	ENSG00000137843	0.42642119298547854	[4,4]	[3,4]	7	hSpCas9	positive selection	3077339
40264950	40264973	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	-0.11298027398939092	[2,2]	[3,0]	-2	hSpCas9	positive selection	3077340
40264948	40264971	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.10211696119530442	[2,2]	[3,0]	-1	hSpCas9	positive selection	3077341
40272666	40272689		+	24336571	A375	resistance to PLX after 7 days	CCGTCAAGATGATGGACCTCAGG	PAK6	ENSG00000137843	-0.22495230291151433	[14,12]	[9,13]	-7	hSpCas9	positive selection	3133820
40266257	40266280		+	24336571	A375	resistance to PLX after 7 days	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	-0.06495682079801912	[3,4]	[3,4]	-2	hSpCas9	positive selection	3133823
40272323	40272346		-	24336571	A375	resistance to PLX after 7 days	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	-0.4120069533295636	[5,5]	[3,4]	-9	hSpCas9	positive selection	3133824
40266402	40266425		-	24336571	A375	resistance to PLX after 7 days	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	-0.1722790944595468	[15,15]	[12,14]	-5	hSpCas9	positive selection	3133825
40272666	40272689		+	24336571	A375	resistance to PLX after 14 days	CCGTCAAGATGATGGACCTCAGG	PAK6	ENSG00000137843	-0.8496119066456943	[21,11]	[3,3]	-8	hSpCas9	positive selection	3191613
40266257	40266280		+	24336571	A375	resistance to PLX after 14 days	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.8063091177057147	[2,3]	[2,1]	6	hSpCas9	positive selection	3191616
40272323	40272346		-	24336571	A375	resistance to PLX after 14 days	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	-0.3932585203081107	[6,5]	[1,1]	-5	hSpCas9	positive selection	3191617
40266402	40266425		-	24336571	A375	resistance to PLX after 14 days	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	-0.255398279641314	[15,12]	[5,4]	-3	hSpCas9	positive selection	3191618
40272666	40272689		+	24336571	A375	viability after 7 days	CCGTCAAGATGATGGACCTCAGG	PAK6	ENSG00000137843	0.6026137675658954	[9]	[14,12]	8	hSpCas9	negative selection	3249406
40266257	40266280		+	24336571	A375	viability after 7 days	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.4380129717033754	[2]	[3,4]	6	hSpCas9	negative selection	3249409
40272323	40272346		-	24336571	A375	viability after 7 days	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.3439693872628202	[4]	[5,5]	5	hSpCas9	negative selection	3249410
40266402	40266425		-	24336571	A375	viability after 7 days	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.3822786738139672	[12]	[15,15]	6	hSpCas9	negative selection	3249411
40272666	40272689		+	24336571	A375	viability after 14 days	CCGTCAAGATGATGGACCTCAGG	PAK6	ENSG00000137843	0.8599154927942273	[9]	[21,11]	9	hSpCas9	negative selection	3307199
40266257	40266280		+	24336571	A375	viability after 14 days	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.003722103753102113	[2]	[2,3]	0	hSpCas9	negative selection	3307202
40272323	40272346		-	24336571	A375	viability after 14 days	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.3786903493483904	[4]	[6,5]	5	hSpCas9	negative selection	3307203
40266402	40266425		-	24336571	A375	viability after 14 days	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.27036075644430685	[12]	[15,12]	3	hSpCas9	negative selection	3307204
40266402	40266425	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	-0.28956824844180157	[186,186]	[0,0]	-2	hSpCas9	positive selection	3384524
40272408	40272431	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.13838513872232763	[138,138]	[0,0]	0	hSpCas9	positive selection	3384525
40272978	40273001	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	-0.7760967900916153	[261,261]	[0,0]	-5	hSpCas9	positive selection	3384526
40266180	40266203	15	-	26780180	HT29	viability (Avana library 4 designs)	AGGCACCCTGAAACTCGGCGGGG	PAK6	ENSG00000137843	0.764852667924759	[]	[]	3	hSpCas9	negative selection	3447517
40266063	40266086	15	+	26780180	HT29	viability (Avana library 4 designs)	CCTCTACCTCAGCTGCAACGGGG	PAK6	ENSG00000137843	-0.729543206401724	[]	[]	-8	hSpCas9	negative selection	3447518
40264950	40264973	15	-	26780180	HT29	viability (Avana library 4 designs)	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	1.29973156031904	[]	[]	5	hSpCas9	negative selection	3447519
40264947	40264970	15	+	26780180	HT29	viability (Avana library 4 designs)	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	2.52146378824981	[]	[]	8	hSpCas9	negative selection	3447520
40266180	40266203	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCACCCTGAAACTCGGCGGGG	PAK6	ENSG00000137843	0.0330420038348624	[]	[]	0	hSpCas9	negative selection	3541361
40264950	40264973	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	5.48230632717012	[]	[]	8	hSpCas9	negative selection	3541362
40264947	40264970	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-7.0240354388405	[]	[]	-6	hSpCas9	negative selection	3541363
40266063	40266086	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCTACCTCAGCTGCAACGGGG	PAK6	ENSG00000137843	-3.11796478609198	[]	[]	-4	hSpCas9	negative selection	3541364
40265826	40265849	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCTTCCCCCTACAGACAGTGG	PAK6	ENSG00000137843	-3.24612244555575	[]	[]	-4	hSpCas9	negative selection	3541365
40264907	40264930	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-5.27329979832679	[]	[]	-5	hSpCas9	negative selection	3541366
40266180	40266203	15	-	26780180	A375	viability (Avana lentiGuide)	AGGCACCCTGAAACTCGGCGGGG	PAK6	ENSG00000137843	4.94697656215249	[]	[]	4	hSpCas9	negative selection	3650020
40264950	40264973	15	-	26780180	A375	viability (Avana lentiGuide)	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	4.6099253512612	[]	[]	4	hSpCas9	negative selection	3650021
40264947	40264970	15	+	26780180	A375	viability (Avana lentiGuide)	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	8.23878874605883	[]	[]	6	hSpCas9	negative selection	3650022
40266063	40266086	15	+	26780180	A375	viability (Avana lentiGuide)	CCTCTACCTCAGCTGCAACGGGG	PAK6	ENSG00000137843	1.53785031457014	[]	[]	1	hSpCas9	negative selection	3650023
40265826	40265849	15	+	26780180	A375	viability (Avana lentiGuide)	TCTCTTCCCCCTACAGACAGTGG	PAK6	ENSG00000137843	12.6795768670725	[]	[]	7	hSpCas9	negative selection	3650024
40264907	40264930	15	+	26780180	A375	viability (Avana lentiGuide)	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.106683558783989	[]	[]	0	hSpCas9	negative selection	3650025
40266180	40266203	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCACCCTGAAACTCGGCGGGG	PAK6	ENSG00000137843	0.043466953706477005	[4]	[4,4]	1	hSpCas9	positive selection	3758679
40264950	40264973	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	0.08321448491464495	[3]	[4,3]	2	hSpCas9	positive selection	3758680
40264947	40264970	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.4280241600746432	[3]	[2,2]	-6	hSpCas9	positive selection	3758681
40266063	40266086	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCTACCTCAGCTGCAACGGGG	PAK6	ENSG00000137843	0.046009592757866695	[5]	[4,5]	1	hSpCas9	positive selection	3758682
40265826	40265849	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCTTCCCCCTACAGACAGTGG	PAK6	ENSG00000137843	-0.5405504988322873	[1]	[0,1]	-7	hSpCas9	positive selection	3758683
40264907	40264930	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.15973630707294867	[6]	[5,5]	-3	hSpCas9	positive selection	3758684
40266180	40266203	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCACCCTGAAACTCGGCGGGG	PAK6	ENSG00000137843	-0.22973213669640413	[5]	[3,3]	-3	hSpCas9	positive selection	3867286
40264950	40264973	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACCCGTGTGATTCGCGAAGGG	PAK6	ENSG00000137843	-1.1444577206777666	[4]	[0,1]	-8	hSpCas9	positive selection	3867287
40264947	40264970	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.12556247952038796	[5]	[4,3]	-2	hSpCas9	positive selection	3867288
40266063	40266086	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCTACCTCAGCTGCAACGGGG	PAK6	ENSG00000137843	0.15459883245746997	[6]	[5,6]	3	hSpCas9	positive selection	3867289
40265826	40265849	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCTTCCCCCTACAGACAGTGG	PAK6	ENSG00000137843	-0.24903062149485172	[3]	[2,2]	-3	hSpCas9	positive selection	3867290
40264907	40264930	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.1173122024908359	[7]	[6,6]	2	hSpCas9	positive selection	3867291
40272978	40273001	15	+	26780180	A375	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.68346753873053	[]	[]	2	hSpCas9	negative selection	3978183
40272408	40272431	15	+	26780180	A375	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	1.27568021263058	[]	[]	7	hSpCas9	negative selection	3978184
40266257	40266280	15	+	26780180	A375	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.406602225240271	[]	[]	1	hSpCas9	negative selection	3978185
40272883	40272906	15	+	26780180	A375	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.773878754986168	[]	[]	3	hSpCas9	negative selection	3978186
40272323	40272346	15	-	26780180	A375	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	-0.00278020886399749	[]	[]	0	hSpCas9	negative selection	3978187
40266402	40266425	15	-	26780180	A375	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	1.26709911322438	[]	[]	7	hSpCas9	negative selection	3978188
40272978	40273001	15	+	26780180	HT29	viability (GeCKOv2 library)	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	1.07001982758896	[]	[]	5	hSpCas9	negative selection	4086149
40272408	40272431	15	+	26780180	HT29	viability (GeCKOv2 library)	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	2.46563264483669	[]	[]	9	hSpCas9	negative selection	4086150
40266257	40266280	15	+	26780180	HT29	viability (GeCKOv2 library)	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	1.16230821402874	[]	[]	5	hSpCas9	negative selection	4086151
40272883	40272906	15	+	26780180	HT29	viability (GeCKOv2 library)	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.509944621172799	[]	[]	1	hSpCas9	negative selection	4086152
40272323	40272346	15	-	26780180	HT29	viability (GeCKOv2 library)	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	-0.0466818681136601	[]	[]	-1	hSpCas9	negative selection	4086153
40266402	40266425	15	-	26780180	HT29	viability (GeCKOv2 library)	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.962999190345092	[]	[]	4	hSpCas9	negative selection	4086154
40272666	40272689	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGTCAAGATGATGGACCTCAGG	PAK6	ENSG00000137843	-0.3159507822976877	[3]	[1,1]	-6	hSpCas9	positive selection	4158667
40266257	40266280	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.3064017458765688	[1]	[1,1]	7	hSpCas9	positive selection	4158670
40272323	40272346	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	-0.3539056249116348	[1]	[0,0]	-7	hSpCas9	positive selection	4158671
40266402	40266425	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.13286437518019115	[3]	[2,2]	3	hSpCas9	positive selection	4158672
40272666	40272689	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGTCAAGATGATGGACCTCAGG	PAK6	ENSG00000137843	0.1781863984675587	[4]	[4,2,2,0]	1	hSpCas9	positive selection	4222689
40266257	40266280	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.9784709049799809	[0]	[0,0,0,0]	6	hSpCas9	positive selection	4222692
40272323	40272346	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.17697214452455373	[2]	[3,0,0,0]	1	hSpCas9	positive selection	4222693
40266402	40266425	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.9599634005891639	[3]	[1,0,1,3]	6	hSpCas9	positive selection	4222694
40266257	40266280	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	-0.10270096254201945	[3]	[2,1]	-2	hSpCas9	positive selection	4288701
40272883	40272906	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.2893696984412145	[1]	[1,0]	-5	hSpCas9	positive selection	4288702
40272323	40272346	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.043518923243996366	[4]	[4,2]	0	hSpCas9	positive selection	4288703
40266402	40266425	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	-0.08188392363494577	[3]	[3,1]	-2	hSpCas9	positive selection	4352954
40272408	40272431	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	-0.5428102296742962	[2]	[1,0]	-8	hSpCas9	positive selection	4352955
40272978	40273001	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.1803173467015482	[3]	[3,2]	3	hSpCas9	positive selection	4352956
40264939	40264961	15	-	27760321	OCIAML3	viability	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.43577520632994904	[476,449]	[396,612]	5	hSpCas9	negative selection	4425414
40266185	40266207	15	-	27760321	OCIAML3	viability	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	-0.01779711822034835	[303,293]	[220,244]	0	hSpCas9	negative selection	4425415
40266263	40266285	15	-	27760321	OCIAML3	viability	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	1.1155294295717544	[1180,1001]	[1732,1986]	9	hSpCas9	negative selection	4425416
40272231	40272253	15	-	27760321	OCIAML3	viability	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	-0.3619626693426735	[347,449]	[233,261]	-4	hSpCas9	negative selection	4425417
40272290	40272312	15	+	27760321	OCIAML3	viability	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.3136867493098262	[763,661]	[669,718]	3	hSpCas9	negative selection	4425418
40264939	40264961	15	-	27760321	OCIAML2	viability	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	-0.393704871570788	[476,449]	[251,329]	-4	hSpCas9	negative selection	4508877
40266185	40266207	15	-	27760321	OCIAML2	viability	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	0.5026804906086315	[303,293]	[269,439]	7	hSpCas9	negative selection	4508878
40266263	40266285	15	-	27760321	OCIAML2	viability	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	0.4474136273487712	[1180,1001]	[1050,1395]	6	hSpCas9	negative selection	4508879
40272231	40272253	15	-	27760321	OCIAML2	viability	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	0.09759445739880136	[347,449]	[331,373]	1	hSpCas9	negative selection	4508880
40272290	40272312	15	+	27760321	OCIAML2	viability	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.6122004554563863	[763,661]	[717,1091]	8	hSpCas9	negative selection	4508881
40264939	40264961	15	-	27760321	MV411	viability	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	-0.5562040495318136	[476,449]	[208,206]	-4	hSpCas9	negative selection	4592340
40266185	40266207	15	-	27760321	MV411	viability	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	2.470565532492217	[303,293]	[1703,181]	9	hSpCas9	negative selection	4592341
40266263	40266285	15	-	27760321	MV411	viability	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	0.6024630376891211	[1180,1001]	[895,1380]	4	hSpCas9	negative selection	4592342
40272231	40272253	15	-	27760321	MV411	viability	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	0.04565053222091796	[347,449]	[165,439]	0	hSpCas9	negative selection	4592343
40272290	40272312	15	+	27760321	MV411	viability	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.9257854147573868	[763,661]	[797,1031]	6	hSpCas9	negative selection	4592344
40264939	40264961	15	-	27760321	HL60	viability	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.187346655664964	[476,449]	[464,395]	2	hSpCas9	negative selection	4675803
40266185	40266207	15	-	27760321	HL60	viability	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	1.1904815904503927	[303,293]	[508,610]	9	hSpCas9	negative selection	4675804
40266263	40266285	15	-	27760321	HL60	viability	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	0.5157053681971546	[1180,1001]	[1049,1503]	6	hSpCas9	negative selection	4675805
40272231	40272253	15	-	27760321	HL60	viability	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	0.20689649895189172	[347,449]	[426,332]	2	hSpCas9	negative selection	4675806
40272290	40272312	15	+	27760321	HL60	viability	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.4546932144910959	[763,661]	[734,860]	5	hSpCas9	negative selection	4675807
40264939	40264961	15	-	27760321	HT1080	viability	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.4660141747012172	[449,350]	[164,280]	2	hSpCas9	negative selection	4759266
40266185	40266207	15	-	27760321	HT1080	viability	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	0.8997848100102956	[293,229]	[231,153]	5	hSpCas9	negative selection	4759267
40266263	40266285	15	-	27760321	HT1080	viability	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	0.9668485420161366	[1001,781]	[684,704]	5	hSpCas9	negative selection	4759268
40272231	40272253	15	-	27760321	HT1080	viability	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	1.4603460532499306	[449,350]	[470,403]	7	hSpCas9	negative selection	4759269
40272290	40272312	15	+	27760321	HT1080	viability	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	-0.37710411258885057	[661,516]	[113,253]	-2	hSpCas9	negative selection	4759270
40264939	40264961	15	-	27760321	HT29	viability after 7 days	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.19362202528458586	[449,350]	[580,574,607]	3	hSpCas9	negative selection	4842729
40266185	40266207	15	-	27760321	HT29	viability after 7 days	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	0.23336997584949856	[293,229]	[437,340,413]	3	hSpCas9	negative selection	4842730
40266263	40266285	15	-	27760321	HT29	viability after 7 days	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	0.692661507624476	[1001,781]	[2202,2028,1390]	9	hSpCas9	negative selection	4842731
40272231	40272253	15	-	27760321	HT29	viability after 7 days	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	-0.318262458033541	[449,350]	[499,377,373]	-4	hSpCas9	negative selection	4842732
40272290	40272312	15	+	27760321	HT29	viability after 7 days	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.4085978675244568	[661,516]	[895,902,1195]	6	hSpCas9	negative selection	4842733
40264939	40264961	15	-	27760321	HT29	viability after 25 days	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.5254089419830762	[449,350]	[439,709,859]	6	hSpCas9	negative selection	4926192
40266185	40266207	15	-	27760321	HT29	viability after 25 days	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	0.7785323455979243	[293,229]	[440,571,533]	8	hSpCas9	negative selection	4926193
40266263	40266285	15	-	27760321	HT29	viability after 25 days	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	0.9092198116075618	[1001,781]	[1921,1825,2000]	9	hSpCas9	negative selection	4926194
40272231	40272253	15	-	27760321	HT29	viability after 25 days	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	0.05632846676128575	[449,350]	[652,276,486]	0	hSpCas9	negative selection	4926195
40272290	40272312	15	+	27760321	HT29	viability after 25 days	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.6907308552231608	[661,516]	[1127,1181,931]	7	hSpCas9	negative selection	4926196
40264939	40264961	15	-	27760321	HT29	viability after 22 days	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.31658503615240075	[449,350]	[573,558,596]	3	hSpCas9	negative selection	5009655
40266185	40266207	15	-	27760321	HT29	viability after 22 days	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	0.4335268797550635	[293,229]	[428,366,430]	5	hSpCas9	negative selection	5009656
40266263	40266285	15	-	27760321	HT29	viability after 22 days	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	0.9738487152616164	[1001,781]	[2035,2395,1639]	9	hSpCas9	negative selection	5009657
40272231	40272253	15	-	27760321	HT29	viability after 22 days	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	0.13956133012825403	[449,350]	[491,369,669]	1	hSpCas9	negative selection	5009658
40272290	40272312	15	+	27760321	HT29	viability after 22 days	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.5756859520679278	[661,516]	[899,952,1198]	6	hSpCas9	negative selection	5009659
40264939	40264961	15	-	27760321	HT29	viability after 19 days	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.14006901006886827	[449,350]	[658,339,529]	1	hSpCas9	negative selection	5093118
40266185	40266207	15	-	27760321	HT29	viability after 19 days	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	0.7527306145891344	[293,229]	[375,698,428]	7	hSpCas9	negative selection	5093119
40266263	40266285	15	-	27760321	HT29	viability after 19 days	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	1.0843295232980936	[1001,781]	[1849,2196,2398]	9	hSpCas9	negative selection	5093120
40272231	40272253	15	-	27760321	HT29	viability after 19 days	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	0.22415951713183516	[449,350]	[592,515,502]	2	hSpCas9	negative selection	5093121
40272290	40272312	15	+	27760321	HT29	viability after 19 days	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.4749177247298628	[661,516]	[1098,509,1207]	5	hSpCas9	negative selection	5093122
40264939	40264961	15	-	27760321	HT29	viability after 16 days	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.3688125093086193	[449,350]	[559,497,677]	4	hSpCas9	negative selection	5176581
40266185	40266207	15	-	27760321	HT29	viability after 16 days	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	0.3789833406901962	[293,229]	[451,394,302]	4	hSpCas9	negative selection	5176582
40266263	40266285	15	-	27760321	HT29	viability after 16 days	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	0.6740343235158404	[1001,781]	[1939,1571,1297]	7	hSpCas9	negative selection	5176583
40272231	40272253	15	-	27760321	HT29	viability after 16 days	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	0.15927344724055306	[449,350]	[438,546,507]	1	hSpCas9	negative selection	5176584
40272290	40272312	15	+	27760321	HT29	viability after 16 days	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.8092366493108603	[661,516]	[1147,1128,1189]	8	hSpCas9	negative selection	5176585
40264939	40264961	15	-	27760321	HT29	viability after 13 days	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	0.11321241868695744	[449,350]	[616,502,393]	1	hSpCas9	negative selection	5260044
40266185	40266207	15	-	27760321	HT29	viability after 13 days	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	0.1008708017148654	[293,229]	[336,298,340]	1	hSpCas9	negative selection	5260045
40266263	40266285	15	-	27760321	HT29	viability after 13 days	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	0.6539237760492929	[1001,781]	[1621,1593,1665]	8	hSpCas9	negative selection	5260046
40272231	40272253	15	-	27760321	HT29	viability after 13 days	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	-0.017795502511616074	[449,350]	[513,445,418]	0	hSpCas9	negative selection	5260047
40272290	40272312	15	+	27760321	HT29	viability after 13 days	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.3943267326387221	[661,516]	[988,854,854]	5	hSpCas9	negative selection	5260048
40264939	40264961	15	-	27760321	HT29	viability after 10 days	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	-0.1756748756763185	[449,350]	[431,506,391]	-2	hSpCas9	negative selection	5343507
40266185	40266207	15	-	27760321	HT29	viability after 10 days	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	0.7955542764432986	[293,229]	[533,591,577]	9	hSpCas9	negative selection	5343508
40266263	40266285	15	-	27760321	HT29	viability after 10 days	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	0.670923742326492	[1001,781]	[1763,1574,1969]	8	hSpCas9	negative selection	5343509
40272231	40272253	15	-	27760321	HT29	viability after 10 days	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	-0.14223757479461063	[449,350]	[391,476,489]	-2	hSpCas9	negative selection	5343510
40272290	40272312	15	+	27760321	HT29	viability after 10 days	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.48966648116148614	[661,516]	[1233,1016,852]	6	hSpCas9	negative selection	5343511
40264939	40264961	15	-	27760321	MOLM13	viability	TTCGCGAAGGGTCCACCACGGG	PAK6	ENSG00000137843	-1.4361027705377327	[476,449]	[133,64]	-7	hSpCas9	negative selection	5426970
40266185	40266207	15	-	27760321	MOLM13	viability	TGCGAGGCACCCTGAAACTCGG	PAK6	ENSG00000137843	0.4525702783778492	[303,293]	[381,102]	3	hSpCas9	negative selection	5426971
40266263	40266285	15	-	27760321	MOLM13	viability	CCATGCCTATTGGTGCCCGTGG	PAK6	ENSG00000137843	0.7850869626324972	[1180,1001]	[794,1280]	5	hSpCas9	negative selection	5426972
40272231	40272253	15	-	27760321	MOLM13	viability	TTCTGCGGCGGTCGGAAAGAGG	PAK6	ENSG00000137843	-0.8827886477625303	[347,449]	[173,80]	-5	hSpCas9	negative selection	5426973
40272290	40272312	15	+	27760321	MOLM13	viability	TTGCCCTCGGACCAGCCGGTGG	PAK6	ENSG00000137843	0.7827132661986916	[763,661]	[484,864]	5	hSpCas9	negative selection	5426974
40239079	40239102	15	+	27661255	K562	viability	GCTCGGCGCCCCAAACGAGCAGG	PAK6	ENSG00000137843	0.21091470198662643	[84,140]	[102,103]	7	dCas9-KRAB	negative selection	5500007
40239101	40239124	15	+	27661255	K562	viability	GTCGATGCCTGAGGATTTAATGG	PAK6	ENSG00000137843	0.14980138846276933	[849,936]	[804,777]	5	dCas9-KRAB	negative selection	5500008
40239267	40239290	15	+	27661255	K562	viability	GAGACAGCCACGGTCCAGGCAGG	PAK6	ENSG00000137843	0.15227004183441298	[931,776]	[807,720]	5	dCas9-KRAB	negative selection	5500009
40239307	40239330	15	-	27661255	K562	viability	GGCTCCTGGCACATCAGGACGGG	PAK6	ENSG00000137843	-0.0859515332910672	[282,223]	[203,180]	-3	dCas9-KRAB	negative selection	5500012
40239568	40239591	15	-	27661255	K562	viability	GCCTGCTGCCACAGCCCCCCGGG	PAK6	ENSG00000137843	-0.07940804566354531	[488,450]	[384,330]	-3	dCas9-KRAB	negative selection	5500013
40266257	40266280	15	+	27260156	BXPC3	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.30089687982873764	[499]	[591,667,591,733]	6	hSpCas9	negative selection	5561161
40272883	40272906	15	+	27260156	BXPC3	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.5376345122878723	[91]	[140,162,123,125]	9	hSpCas9	negative selection	5561162
40272323	40272346	15	-	27260156	BXPC3	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.02477454523442657	[1004]	[1029,964,924,1396]	0	hSpCas9	negative selection	5561163
40266402	40266425	15	-	27260156	BXPC3	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.2745471820790211	[501]	[644,527,726,642]	6	hSpCas9	negative selection	5625414
40272408	40272431	15	+	27260156	BXPC3	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.27259694886568203	[430]	[453,536,574,628]	6	hSpCas9	negative selection	5625415
40272978	40273001	15	+	27260156	BXPC3	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.12310059564171283	[747]	[892,854,878,757]	2	hSpCas9	negative selection	5625416
40266257	40266280	15	+	27260156	A673	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.31889372101015045	[499]	[785,615,701,906]	7	hSpCas9	negative selection	5682412
40272883	40272906	15	+	27260156	A673	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.4031222619767445	[91]	[166,132,108,179]	8	hSpCas9	negative selection	5682413
40272323	40272346	15	-	27260156	A673	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	-0.023079782894315892	[1004]	[1305,1235,1086,1128]	0	hSpCas9	negative selection	5682414
40266402	40266425	15	-	27260156	A673	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.11947981156781123	[501]	[820,556,637,621]	3	hSpCas9	negative selection	5746665
40272408	40272431	15	+	27260156	A673	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.13348142963578635	[430]	[677,472,504,632]	3	hSpCas9	negative selection	5746666
40272978	40273001	15	+	27260156	A673	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.12384446828258444	[747]	[954,913,1016,1027]	3	hSpCas9	negative selection	5746667
40266257	40266280	15	+	27260156	A375	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.7138757498700882	[499]	[974,1234,1008,680]	9	hSpCas9	negative selection	5803663
40272883	40272906	15	+	27260156	A375	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.7546815807122131	[91]	[78,44,54,71]	-7	hSpCas9	negative selection	5803664
40272323	40272346	15	-	27260156	A375	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.07486341976224864	[1004]	[1337,1385,1203,1055]	1	hSpCas9	negative selection	5803665
40266402	40266425	15	-	27260156	A375	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.26202134579677683	[501]	[755,686,644,717]	4	hSpCas9	negative selection	5867916
40272408	40272431	15	+	27260156	A375	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.07328545036958324	[430]	[505,356,622,597]	1	hSpCas9	negative selection	5867917
40272978	40273001	15	+	27260156	A375	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.16234141431480142	[747]	[742,985,1019,1137]	2	hSpCas9	negative selection	5867918
40266257	40266280	15	+	27260156	COLO741	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.45550605636747044	[499]	[1070,802,775]	8	hSpCas9	negative selection	5924914
40272883	40272906	15	+	27260156	COLO741	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.3584181135529092	[91]	[123,194,131]	7	hSpCas9	negative selection	5924915
40272323	40272346	15	-	27260156	COLO741	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.35438174721474414	[1004]	[1798,1364,1760]	7	hSpCas9	negative selection	5924916
40266402	40266425	15	-	27260156	COLO741	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.1912117034741726	[501]	[933,573,705]	4	hSpCas9	negative selection	5989167
40272408	40272431	15	+	27260156	COLO741	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	-0.027034334630613874	[430]	[476,653,487]	0	hSpCas9	negative selection	5989168
40272978	40273001	15	+	27260156	COLO741	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.1095997300440712	[747]	[1181,811,1103]	2	hSpCas9	negative selection	5989169
40266257	40266280	15	+	27260156	CAL120	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.6172808829451779	[499]	[1144,759,985]	8	hSpCas9	negative selection	6046165
40272883	40272906	15	+	27260156	CAL120	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.0740277350157208	[91]	[71,100,146]	-1	hSpCas9	negative selection	6046166
40272323	40272346	15	-	27260156	CAL120	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.2992001998395972	[1004]	[1244,1975,1353]	4	hSpCas9	negative selection	6046167
40266402	40266425	15	-	27260156	CAL120	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.5289686448310408	[501]	[1451,682,655]	7	hSpCas9	negative selection	6110418
40272408	40272431	15	+	27260156	CAL120	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.16300797854035087	[430]	[868,393,578]	2	hSpCas9	negative selection	6110419
40272978	40273001	15	+	27260156	CAL120	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.13965969449988214	[747]	[1090,1042,952]	2	hSpCas9	negative selection	6110420
40266257	40266280	15	+	27260156	CADOES1	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.5104358579096338	[499]	[647,637,692,670]	8	hSpCas9	negative selection	6167416
40272883	40272906	15	+	27260156	CADOES1	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.21778477246849892	[91]	[44,129,154,66]	3	hSpCas9	negative selection	6167417
40272323	40272346	15	-	27260156	CADOES1	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.28315940171453047	[1004]	[1194,1252,1110,984]	5	hSpCas9	negative selection	6167418
40266402	40266425	15	-	27260156	CADOES1	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.30238286008781506	[501]	[585,486,699,527]	5	hSpCas9	negative selection	6231669
40272408	40272431	15	+	27260156	CADOES1	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.2979768163864424	[430]	[443,412,702,407]	5	hSpCas9	negative selection	6231670
40272978	40273001	15	+	27260156	CADOES1	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.22007302547299534	[747]	[709,975,819,732]	4	hSpCas9	negative selection	6231671
40266257	40266280	15	+	27260156	EWS502	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.5311403715694877	[499]	[557,870,849,803]	8	hSpCas9	negative selection	6288667
40272883	40272906	15	+	27260156	EWS502	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.30219896740533425	[91]	[135,149,74,114]	5	hSpCas9	negative selection	6288668
40272323	40272346	15	-	27260156	EWS502	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.15833018785648623	[1004]	[1107,1244,1340,1052]	2	hSpCas9	negative selection	6288669
40266402	40266425	15	-	27260156	EWS502	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.39719966557016123	[501]	[642,708,809,639]	7	hSpCas9	negative selection	6352920
40272408	40272431	15	+	27260156	EWS502	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.2647511266673293	[430]	[360,543,677,639]	4	hSpCas9	negative selection	6352921
40272978	40273001	15	+	27260156	EWS502	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.1474640182157262	[747]	[845,838,1080,738]	2	hSpCas9	negative selection	6352922
40266257	40266280	15	+	27260156	EW8	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.5536039844400454	[499]	[670,469,665,565]	8	hSpCas9	negative selection	6409918
40272883	40272906	15	+	27260156	EW8	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.3092204119034032	[91]	[95,90,40,19]	-5	hSpCas9	negative selection	6409919
40272323	40272346	15	-	27260156	EW8	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	-0.059196922094289395	[1004]	[753,746,500,1165]	-1	hSpCas9	negative selection	6409920
40266402	40266425	15	-	27260156	EW8	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.08412649573089687	[501]	[403,465,352,510]	1	hSpCas9	negative selection	6474171
40272408	40272431	15	+	27260156	EW8	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.24633674671710942	[430]	[531,294,362,486]	4	hSpCas9	negative selection	6474172
40272978	40273001	15	+	27260156	EW8	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	-0.0034798419178642126	[747]	[542,629,594,643]	0	hSpCas9	negative selection	6474173
40266257	40266280	15	+	27260156	CORL105	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.30681510433619985	[499]	[827,724,636,695]	6	hSpCas9	negative selection	6531169
40272883	40272906	15	+	27260156	CORL105	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.04213641995953221	[91]	[131,112,83,86]	-1	hSpCas9	negative selection	6531170
40272323	40272346	15	-	27260156	CORL105	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.2730137696379371	[1004]	[1476,1214,1762,1290]	5	hSpCas9	negative selection	6531171
40266402	40266425	15	-	27260156	CORL105	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.2496754590636573	[501]	[664,776,672,672]	4	hSpCas9	negative selection	6595422
40272408	40272431	15	+	27260156	CORL105	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.39427535669124475	[430]	[703,483,683,787]	7	hSpCas9	negative selection	6595423
40272978	40273001	15	+	27260156	CORL105	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.016143475926782225	[747]	[870,844,1048,802]	0	hSpCas9	negative selection	6595424
40266257	40266280	15	+	27260156	HS294T	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.641155520508562	[499]	[318,302,310,263]	8	hSpCas9	negative selection	6652420
40272883	40272906	15	+	27260156	HS294T	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.061005338296879597	[91]	[36,40,23,47]	0	hSpCas9	negative selection	6652421
40272323	40272346	15	-	27260156	HS294T	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.5212690041470796	[1004]	[470,526,344,962]	7	hSpCas9	negative selection	6652422
40266402	40266425	15	-	27260156	HS294T	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.2405515908324934	[501]	[175,247,172,342]	3	hSpCas9	negative selection	6716673
40272408	40272431	15	+	27260156	HS294T	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.7528442848877601	[430]	[241,400,217,256]	8	hSpCas9	negative selection	6716674
40272978	40273001	15	+	27260156	HS294T	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.07453411258152343	[747]	[237,267,283,460]	1	hSpCas9	negative selection	6716675
40266257	40266280	15	+	27260156	HCC44	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.5181002952766292	[499]	[836,848,819,727]	8	hSpCas9	negative selection	6773671
40272883	40272906	15	+	27260156	HCC44	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.37988835923424835	[91]	[71,30,132,97]	-5	hSpCas9	negative selection	6773672
40272323	40272346	15	-	27260156	HCC44	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.11175254772020682	[1004]	[1049,1322,1446,1094]	1	hSpCas9	negative selection	6773673
40266402	40266425	15	-	27260156	HCC44	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.1484727310823608	[501]	[676,542,613,689]	2	hSpCas9	negative selection	6837924
40272408	40272431	15	+	27260156	HCC44	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.10689181745686473	[430]	[446,399,808,499]	1	hSpCas9	negative selection	6837925
40272978	40273001	15	+	27260156	HCC44	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	-0.006390732042837577	[747]	[1067,792,943,609]	0	hSpCas9	negative selection	6837926
40266257	40266280	15	+	27260156	G402	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.7926828876633605	[499]	[1583,1313,1112,338]	8	hSpCas9	negative selection	6894922
40272883	40272906	15	+	27260156	G402	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.8377619334767878	[91]	[46,47,71,79]	-7	hSpCas9	negative selection	6894923
40272323	40272346	15	-	27260156	G402	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	-0.3406391803604817	[1004]	[1467,784,914,772]	-4	hSpCas9	negative selection	6894924
40266402	40266425	15	-	27260156	G402	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.3150351593223042	[501]	[856,910,907,408]	4	hSpCas9	negative selection	6959175
40272408	40272431	15	+	27260156	G402	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.6085977171670122	[430]	[741,758,989,706]	7	hSpCas9	negative selection	6959176
40272978	40273001	15	+	27260156	G402	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.11989251678613466	[747]	[1109,704,1013,1127]	1	hSpCas9	negative selection	6959177
40266257	40266280	15	+	27260156	L33	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.14120245015163957	[499]	[586,204,334,583]	3	hSpCas9	negative selection	7016173
40272883	40272906	15	+	27260156	L33	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.3708483900720809	[91]	[99,55,64,135]	7	hSpCas9	negative selection	7016174
40272323	40272346	15	-	27260156	L33	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.23106849876253288	[1004]	[1222,497,769,1054]	5	hSpCas9	negative selection	7016175
40266402	40266425	15	-	27260156	L33	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	-0.048269818195409236	[501]	[574,224,249,417]	-1	hSpCas9	negative selection	7080426
40272408	40272431	15	+	27260156	L33	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	-0.07001332441149714	[430]	[361,176,290,386]	-1	hSpCas9	negative selection	7080427
40272978	40273001	15	+	27260156	L33	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	-0.060035772448673974	[747]	[789,285,452,659]	-1	hSpCas9	negative selection	7080428
40266257	40266280	15	+	27260156	K562	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.9440760738171684	[499]	[819,840,914,833]	9	hSpCas9	negative selection	7137424
40272883	40272906	15	+	27260156	K562	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.5429865857197342	[91]	[231,40,102,105]	7	hSpCas9	negative selection	7137425
40272323	40272346	15	-	27260156	K562	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.3449921823064568	[1004]	[1080,1404,1177,899]	4	hSpCas9	negative selection	7137426
40266402	40266425	15	-	27260156	K562	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.4857439367382974	[501]	[979,753,381,434]	6	hSpCas9	negative selection	7201677
40272408	40272431	15	+	27260156	K562	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.36368814349886014	[430]	[468,821,444,271]	4	hSpCas9	negative selection	7201678
40272978	40273001	15	+	27260156	K562	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.36186966105265084	[747]	[1262,962,492,741]	4	hSpCas9	negative selection	7201679
40266257	40266280	15	+	27260156	HT29	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.39298578839997395	[499]	[748,879,727,828]	7	hSpCas9	negative selection	7258675
40272883	40272906	15	+	27260156	HT29	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.6045122501934947	[91]	[83,318,164,122]	9	hSpCas9	negative selection	7258676
40272323	40272346	15	-	27260156	HT29	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.22704534091667816	[1004]	[1594,1737,1215,1224]	4	hSpCas9	negative selection	7258677
40266402	40266425	15	-	27260156	HT29	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.00017610697329280278	[501]	[684,556,612,585]	0	hSpCas9	negative selection	7322928
40272408	40272431	15	+	27260156	HT29	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.34118249278863866	[430]	[772,689,590,612]	6	hSpCas9	negative selection	7322929
40272978	40273001	15	+	27260156	HT29	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	-0.013219152508325838	[747]	[1144,940,869,689]	0	hSpCas9	negative selection	7322930
40266257	40266280	15	+	27260156	MHHES1	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.5418380317219273	[499]	[1108,923,757,572]	8	hSpCas9	negative selection	7379926
40272883	40272906	15	+	27260156	MHHES1	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.10889991954666778	[91]	[189,153,105,27]	2	hSpCas9	negative selection	7379927
40272323	40272346	15	-	27260156	MHHES1	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.4426395017460696	[1004]	[1569,1535,1877,1215]	7	hSpCas9	negative selection	7379928
40266402	40266425	15	-	27260156	MHHES1	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.2606111046945617	[501]	[974,819,712,320]	5	hSpCas9	negative selection	7444179
40272408	40272431	15	+	27260156	MHHES1	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.2480526707754574	[430]	[781,534,650,389]	4	hSpCas9	negative selection	7444180
40272978	40273001	15	+	27260156	MHHES1	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.3924374556128676	[747]	[1677,1025,1012,810]	7	hSpCas9	negative selection	7444181
40266257	40266280	15	+	27260156	MEWO	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.3832454464786432	[499]	[735,526,591]	7	hSpCas9	negative selection	7501177
40272883	40272906	15	+	27260156	MEWO	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.24530193585341165	[91]	[74,63,161]	5	hSpCas9	negative selection	7501178
40272323	40272346	15	-	27260156	MEWO	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.07047458849117305	[1004]	[1136,927,925]	1	hSpCas9	negative selection	7501179
40266402	40266425	15	-	27260156	MEWO	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.15798188994466228	[501]	[571,562,445]	3	hSpCas9	negative selection	7565430
40272408	40272431	15	+	27260156	MEWO	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	-0.22617142427646525	[430]	[430,302,316]	-5	hSpCas9	negative selection	7565431
40272978	40273001	15	+	27260156	MEWO	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	-0.09874944070151825	[747]	[793,567,625]	-2	hSpCas9	negative selection	7565432
40266257	40266280	15	+	27260156	LNCAPCLONEFGC	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	1.0061567061602177	[499]	[900,697,1101,979]	9	hSpCas9	negative selection	7622428
40272883	40272906	15	+	27260156	LNCAPCLONEFGC	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.02769107270987492	[91]	[68,64,142,72]	0	hSpCas9	negative selection	7622429
40272323	40272346	15	-	27260156	LNCAPCLONEFGC	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.475172527857707	[1004]	[952,992,1950,1289]	7	hSpCas9	negative selection	7622430
40266402	40266425	15	-	27260156	LNCAPCLONEFGC	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.2444896966522092	[501]	[608,366,622,577]	4	hSpCas9	negative selection	7686681
40272408	40272431	15	+	27260156	LNCAPCLONEFGC	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.4750175284036213	[430]	[568,501,579,526]	7	hSpCas9	negative selection	7686682
40272978	40273001	15	+	27260156	LNCAPCLONEFGC	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.24123640964761017	[747]	[649,833,754,957]	4	hSpCas9	negative selection	7686683
40266257	40266280	15	+	27260156	PANC0327	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.6191968905769534	[499]	[781,631,512,815]	8	hSpCas9	negative selection	7743679
40272883	40272906	15	+	27260156	PANC0327	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.47459895015552256	[91]	[78,19,105,36]	-6	hSpCas9	negative selection	7743680
40272323	40272346	15	-	27260156	PANC0327	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	-0.013756380640038035	[1004]	[712,1033,1104,651]	0	hSpCas9	negative selection	7743681
40266402	40266425	15	-	27260156	PANC0327	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.3772184693310422	[501]	[614,338,844,551]	5	hSpCas9	negative selection	7807932
40272408	40272431	15	+	27260156	PANC0327	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.3539246365883531	[430]	[625,358,445,553]	5	hSpCas9	negative selection	7807933
40272978	40273001	15	+	27260156	PANC0327	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	-0.1581091733840324	[747]	[825,613,417,539]	-2	hSpCas9	negative selection	7807934
40266257	40266280	15	+	27260156	NCIH2009	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.8791959003484451	[499]	[1363,1297,1205]	9	hSpCas9	negative selection	7864930
40272883	40272906	15	+	27260156	NCIH2009	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.2730531115047192	[91]	[68,191,48]	-4	hSpCas9	negative selection	7864931
40272323	40272346	15	-	27260156	NCIH2009	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.14776012964692598	[1004]	[1623,1368,1687]	2	hSpCas9	negative selection	7864932
40266402	40266425	15	-	27260156	NCIH2009	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.06372375116269954	[501]	[876,586,764]	0	hSpCas9	negative selection	7929183
40272408	40272431	15	+	27260156	NCIH2009	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.5549379023940516	[430]	[1328,790,621]	7	hSpCas9	negative selection	7929184
40272978	40273001	15	+	27260156	NCIH2009	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.3993823044167861	[747]	[1601,1214,1362]	5	hSpCas9	negative selection	7929185
40266257	40266280	15	+	27260156	NCIH1373	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.907006536094756	[499]	[1819,647,973,239]	8	hSpCas9	negative selection	7986181
40272883	40272906	15	+	27260156	NCIH1373	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.8179799625337099	[91]	[51,44,89,11]	-7	hSpCas9	negative selection	7986182
40272323	40272346	15	-	27260156	NCIH1373	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.17740578173879706	[1004]	[1555,1278,1254,269]	1	hSpCas9	negative selection	7986183
40266402	40266425	15	-	27260156	NCIH1373	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.5068383991093465	[501]	[978,669,577,269]	5	hSpCas9	negative selection	8050434
40272408	40272431	15	+	27260156	NCIH1373	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.6979115344037278	[430]	[872,731,757,206]	7	hSpCas9	negative selection	8050435
40272978	40273001	15	+	27260156	NCIH1373	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.31459005407153107	[747]	[1207,563,1031,384]	3	hSpCas9	negative selection	8050436
40266257	40266280	15	+	27260156	PATU8902	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	1.0900745108017655	[499]	[1477,1268,1507,1678]	9	hSpCas9	negative selection	8107432
40272883	40272906	15	+	27260156	PATU8902	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-1.8229535563189017	[91]	[11,14,12,120]	-8	hSpCas9	negative selection	8107433
40272323	40272346	15	-	27260156	PATU8902	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.14570977234000515	[1004]	[1667,1156,1316,2170]	1	hSpCas9	negative selection	8107434
40266402	40266425	15	-	27260156	PATU8902	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.6066110436047217	[501]	[1375,666,1182,976]	6	hSpCas9	negative selection	8171685
40272408	40272431	15	+	27260156	PATU8902	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.6679806883036077	[430]	[688,1089,1187,759]	7	hSpCas9	negative selection	8171686
40272978	40273001	15	+	27260156	PATU8902	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.40988969347045123	[747]	[957,1334,1226,2141]	4	hSpCas9	negative selection	8171687
40266257	40266280	15	+	27260156	PANC1	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.39511062831752997	[499]	[456,996,513,399]	6	hSpCas9	negative selection	8228683
40272883	40272906	15	+	27260156	PANC1	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.4801733335955851	[91]	[146,83,119,85]	7	hSpCas9	negative selection	8228684
40272323	40272346	15	-	27260156	PANC1	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.15753321213334592	[1004]	[870,1139,886,972]	2	hSpCas9	negative selection	8228685
40266402	40266425	15	-	27260156	PANC1	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.40582927544378755	[501]	[575,562,599,539]	6	hSpCas9	negative selection	8292936
40272408	40272431	15	+	27260156	PANC1	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.1531169859572798	[430]	[380,551,307,424]	2	hSpCas9	negative selection	8292937
40272978	40273001	15	+	27260156	PANC1	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.3153960436034561	[747]	[1002,872,638,695]	5	hSpCas9	negative selection	8292938
40266257	40266280	15	+	27260156	PANC0813	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.4823558826480083	[499]	[927,853,688,818]	7	hSpCas9	negative selection	8349934
40272883	40272906	15	+	27260156	PANC0813	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.7431708712530307	[91]	[92,50,56,59]	-8	hSpCas9	negative selection	8349935
40272323	40272346	15	-	27260156	PANC0813	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.29794663149448253	[1004]	[1659,1299,1512,1354]	5	hSpCas9	negative selection	8349936
40266402	40266425	15	-	27260156	PANC0813	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	-0.011000671217662891	[501]	[407,553,650,703]	0	hSpCas9	negative selection	8414187
40272408	40272431	15	+	27260156	PANC0813	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.349715930985656	[430]	[681,575,694,630]	5	hSpCas9	negative selection	8414188
40272978	40273001	15	+	27260156	PANC0813	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.00944968287532355	[747]	[965,1030,737,811]	0	hSpCas9	negative selection	8414189
40266257	40266280	15	+	27260156	RDES	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.638549030650261	[499]	[761,880,876,1091]	8	hSpCas9	negative selection	8471185
40272883	40272906	15	+	27260156	RDES	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.021665949990203437	[91]	[100,103,71,156]	0	hSpCas9	negative selection	8471186
40272323	40272346	15	-	27260156	RDES	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.030032768346566874	[1004]	[1009,972,1253,1565]	0	hSpCas9	negative selection	8471187
40266402	40266425	15	-	27260156	RDES	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.5600035682359351	[501]	[686,763,994,1005]	8	hSpCas9	negative selection	8535438
40272408	40272431	15	+	27260156	RDES	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.363132777613827	[430]	[473,633,611,883]	6	hSpCas9	negative selection	8535439
40272978	40273001	15	+	27260156	RDES	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.13950926130243801	[747]	[696,985,1176,963]	2	hSpCas9	negative selection	8535440
40266257	40266280	15	+	27260156	PC3	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.1679908192801277	[499]	[366,445,1118,560]	4	hSpCas9	negative selection	8592436
40272883	40272906	15	+	27260156	PC3	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.01755612214607849	[91]	[27,113,154,121]	0	hSpCas9	negative selection	8592437
40272323	40272346	15	-	27260156	PC3	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.10428542812555253	[1004]	[493,1097,1890,1326]	2	hSpCas9	negative selection	8592438
40266402	40266425	15	-	27260156	PC3	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	-0.02418123054367506	[501]	[282,552,718,546]	0	hSpCas9	negative selection	8656689
40272408	40272431	15	+	27260156	PC3	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.14182299628255618	[430]	[281,445,833,517]	3	hSpCas9	negative selection	8656690
40272978	40273001	15	+	27260156	PC3	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.0032284249329962433	[747]	[530,791,1023,759]	0	hSpCas9	negative selection	8656691
40266257	40266280	15	+	27260156	PATU8988T	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.8769585791519932	[499]	[887,1040,693,947]	9	hSpCas9	negative selection	8713687
40272883	40272906	15	+	27260156	PATU8988T	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.3182571601626685	[91]	[57,34,49,144]	-5	hSpCas9	negative selection	8713688
40272323	40272346	15	-	27260156	PATU8988T	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	-0.1017069256217229	[1004]	[1108,931,665,919]	-2	hSpCas9	negative selection	8713689
40266402	40266425	15	-	27260156	PATU8988T	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.4679077708074961	[501]	[747,602,639,687]	7	hSpCas9	negative selection	8777940
40272408	40272431	15	+	27260156	PATU8988T	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.257154954285665	[430]	[434,365,530,658]	4	hSpCas9	negative selection	8777941
40272978	40273001	15	+	27260156	PATU8988T	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.12264119479316515	[747]	[698,1240,657,576]	2	hSpCas9	negative selection	8777942
40266257	40266280	15	+	27260156	T47D	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.4039505192834564	[499]	[781,814,725,755]	8	hSpCas9	negative selection	8834938
40272883	40272906	15	+	27260156	T47D	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.39114760394307213	[91]	[172,98,147,145]	8	hSpCas9	negative selection	8834939
40272323	40272346	15	-	27260156	T47D	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.1290541430280534	[1004]	[1245,1237,1223,1421]	2	hSpCas9	negative selection	8834940
40266402	40266425	15	-	27260156	T47D	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.22790671740318702	[501]	[655,615,779,691]	5	hSpCas9	negative selection	8899191
40272408	40272431	15	+	27260156	T47D	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.1564246833905452	[430]	[561,507,549,624]	3	hSpCas9	negative selection	8899192
40272978	40273001	15	+	27260156	T47D	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.06767163666896314	[747]	[940,877,897,939]	1	hSpCas9	negative selection	8899193
40266257	40266280	15	+	27260156	SU8686	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.5323735816604597	[499]	[838,610,648,769]	8	hSpCas9	negative selection	8956189
40272883	40272906	15	+	27260156	SU8686	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.430818322102009	[91]	[134,110,140,100]	7	hSpCas9	negative selection	8956190
40272323	40272346	15	-	27260156	SU8686	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.1334025853561398	[1004]	[944,1166,1066,1209]	2	hSpCas9	negative selection	8956191
40266402	40266425	15	-	27260156	SU8686	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.24889532948812848	[501]	[479,513,698,713]	4	hSpCas9	negative selection	9020442
40272408	40272431	15	+	27260156	SU8686	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.2374089455959249	[430]	[466,495,517,541]	4	hSpCas9	negative selection	9020443
40272978	40273001	15	+	27260156	SU8686	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.028897154135018366	[747]	[619,800,701,934]	0	hSpCas9	negative selection	9020444
40266257	40266280	15	+	27260156	SKES1	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.5829452629519937	[499]	[897,850,583,689]	9	hSpCas9	negative selection	9077440
40272883	40272906	15	+	27260156	SKES1	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.19342882039043463	[91]	[82,66,58,106]	-4	hSpCas9	negative selection	9077441
40272323	40272346	15	-	27260156	SKES1	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.052366182984113774	[1004]	[996,1222,1277,702]	1	hSpCas9	negative selection	9077442
40266402	40266425	15	-	27260156	SKES1	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.23754174676388173	[501]	[601,661,568,538]	5	hSpCas9	negative selection	9141693
40272408	40272431	15	+	27260156	SKES1	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.33448502666376756	[430]	[840,541,566,284]	7	hSpCas9	negative selection	9141694
40272978	40273001	15	+	27260156	SKES1	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	-0.16505734113982695	[747]	[637,747,685,596]	-4	hSpCas9	negative selection	9141695
40266257	40266280	15	+	27260156	TOV112D	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.5007921558396082	[499]	[732,709,734,658]	8	hSpCas9	negative selection	9198691
40272883	40272906	15	+	27260156	TOV112D	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.25579113690108146	[91]	[50,59,72,116]	-5	hSpCas9	negative selection	9198692
40272323	40272346	15	-	27260156	TOV112D	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	-0.1457744450006807	[1004]	[874,1024,1063,704]	-3	hSpCas9	negative selection	9198693
40266402	40266425	15	-	27260156	TOV112D	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.35650838616059	[501]	[715,865,495,558]	6	hSpCas9	negative selection	9262944
40272408	40272431	15	+	27260156	TOV112D	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.48336218643330725	[430]	[907,765,471,339]	8	hSpCas9	negative selection	9262945
40272978	40273001	15	+	27260156	TOV112D	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	-0.20252296452183094	[747]	[866,797,542,454]	-4	hSpCas9	negative selection	9262946
40266257	40266280	15	+	27260156	TC71	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.26444624386763466	[499]	[631,743,599,597]	6	hSpCas9	negative selection	9319942
40272883	40272906	15	+	27260156	TC71	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	0.6127234729674895	[91]	[124,160,168,147]	9	hSpCas9	negative selection	9319943
40272323	40272346	15	-	27260156	TC71	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.14711289187346321	[1004]	[1322,1212,1080,1152]	3	hSpCas9	negative selection	9319944
40266402	40266425	15	-	27260156	TC71	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	-0.08802543801190808	[501]	[450,563,477,535]	-2	hSpCas9	negative selection	9384195
40272408	40272431	15	+	27260156	TC71	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	-0.024968040274747208	[430]	[521,466,387,438]	0	hSpCas9	negative selection	9384196
40272978	40273001	15	+	27260156	TC71	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	-0.027695696856137153	[747]	[719,734,751,951]	0	hSpCas9	negative selection	9384197
40266257	40266280	15	+	27260156	TC32	viability	CGCCCCCCACGGGCACCAATAGG	PAK6	ENSG00000137843	0.5447917512014777	[499]	[694,527,822,738]	8	hSpCas9	negative selection	9441193
40272883	40272906	15	+	27260156	TC32	viability	CTACCAGCACTTCAACGTGGTGG	PAK6	ENSG00000137843	-0.8929671484405528	[91]	[27,14,92,71]	-9	hSpCas9	negative selection	9441194
40272323	40272346	15	-	27260156	TC32	viability	CTGGTATCCGAAGTGGTCAGAGG	PAK6	ENSG00000137843	0.15796712025017934	[1004]	[839,1048,1302,1025]	3	hSpCas9	negative selection	9441195
40266402	40266425	15	-	27260156	TC32	viability	TTCGGAATAGCCTGCGCTTCAGG	PAK6	ENSG00000137843	0.2374681006127794	[501]	[465,374,825,658]	4	hSpCas9	negative selection	9505446
40272408	40272431	15	+	27260156	TC32	viability	CAGCGGGATCCCCCCGCACCTGG	PAK6	ENSG00000137843	0.5156529901261772	[430]	[439,471,608,838]	8	hSpCas9	negative selection	9505447
40272978	40273001	15	+	27260156	TC32	viability	CAGACATCGTCTCCCAAGTCAGG	PAK6	ENSG00000137843	0.04504567475083343	[747]	[705,521,913,833]	0	hSpCas9	negative selection	9505448
40264947	40264970	15	+	27869803	HPAFII	viability after 27 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	1.1774394714617638	[149]	[155,196,NaN]	8	hSpCas9	negative selection	9553377
40266064	40266087	15	+	27869803	HPAFII	viability after 27 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.3525070104868875	[915]	[536,243,NaN]	-3	hSpCas9	negative selection	9553378
40272574	40272597	15	-	27869803	HPAFII	viability after 27 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.9524620425979397	[161]	[160,167,NaN]	7	hSpCas9	negative selection	9553379
40272880	40272903	15	+	27869803	HPAFII	viability after 27 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.3418094464979138	[727]	[343,266,NaN]	-3	hSpCas9	negative selection	9553380
40274214	40274237	15	-	27869803	HPAFII	viability after 27 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.22179317105124263	[85]	[43,59,NaN]	1	hSpCas9	negative selection	9553381
40276061	40276084	15	-	27869803	HPAFII	viability after 27 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.36902510152200757	[248]	[90,109,NaN]	-3	hSpCas9	negative selection	9553382
40264947	40264970	15	+	27869803	HPAFII	viability after 15 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	0.5954141074886559	[149]	[303,205,NaN]	6	hSpCas9	negative selection	9635826
40266064	40266087	15	+	27869803	HPAFII	viability after 15 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.3915818928366872	[915]	[1186,478,NaN]	-4	hSpCas9	negative selection	9635827
40272574	40272597	15	-	27869803	HPAFII	viability after 15 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.36395160280424627	[161]	[384,123,NaN]	4	hSpCas9	negative selection	9635828
40272880	40272903	15	+	27869803	HPAFII	viability after 15 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.5327082390629323	[727]	[620,490,NaN]	-5	hSpCas9	negative selection	9635829
40274214	40274237	15	-	27869803	HPAFII	viability after 15 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	1.4282675649202201	[85]	[339,191,NaN]	9	hSpCas9	negative selection	9635830
40276061	40276084	15	-	27869803	HPAFII	viability after 15 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	-0.16782034890083541	[248]	[281,210,NaN]	-2	hSpCas9	negative selection	9635831
40264947	40264970	15	+	27869803	ASPC1	viability after 36 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	0.12007059762095944	[537]	[117,99,344]	1	hSpCas9	negative selection	9718275
40266064	40266087	15	+	27869803	ASPC1	viability after 36 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	0.21632028223557276	[2118]	[841,801,907]	2	hSpCas9	negative selection	9718276
40272574	40272597	15	-	27869803	ASPC1	viability after 36 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	1.3740018361656725	[290]	[370,494,0]	9	hSpCas9	negative selection	9718277
40272880	40272903	15	+	27869803	ASPC1	viability after 36 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.37254095423716227	[1814]	[485,600,397]	-4	hSpCas9	negative selection	9718278
40274214	40274237	15	-	27869803	ASPC1	viability after 36 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.3355562135603948	[259]	[251,0,106]	3	hSpCas9	negative selection	9718279
40276061	40276084	15	-	27869803	ASPC1	viability after 36 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	1.6439701046891633	[442]	[936,428,202]	9	hSpCas9	negative selection	9718280
40264947	40264970	15	+	27869803	PATU8988S	viability after 35 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.038437412875720334	[471]	[228,140,NaN]	0	hSpCas9	negative selection	9800724
40266064	40266087	15	+	27869803	PATU8988S	viability after 35 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	0.04570521220291446	[1811]	[653,852,NaN]	0	hSpCas9	negative selection	9800725
40272574	40272597	15	-	27869803	PATU8988S	viability after 35 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.33661505163930366	[339]	[137,207,NaN]	4	hSpCas9	negative selection	9800726
40272880	40272903	15	+	27869803	PATU8988S	viability after 35 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.43266200733322524	[1296]	[726,682,NaN]	5	hSpCas9	negative selection	9800727
40274214	40274237	15	-	27869803	PATU8988S	viability after 35 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.7164792717110107	[228]	[172,129,NaN]	7	hSpCas9	negative selection	9800728
40276061	40276084	15	-	27869803	PATU8988S	viability after 35 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	0.40292045148153566	[524]	[308,249,NaN]	4	hSpCas9	negative selection	9800729
40264947	40264970	15	+	27869803	PATU8988S	viability after 31 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	-0.17388268675423832	[471]	[150,186,NaN]	-2	hSpCas9	negative selection	9883173
40266064	40266087	15	+	27869803	PATU8988S	viability after 31 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.04741447254265818	[1811]	[520,925,NaN]	0	hSpCas9	negative selection	9883174
40272574	40272597	15	-	27869803	PATU8988S	viability after 31 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.5028052907950695	[339]	[104,302,NaN]	6	hSpCas9	negative selection	9883175
40272880	40272903	15	+	27869803	PATU8988S	viability after 31 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.3966550819631971	[1296]	[631,742,NaN]	5	hSpCas9	negative selection	9883176
40274214	40274237	15	-	27869803	PATU8988S	viability after 31 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.4395589294848853	[228]	[107,143,NaN]	5	hSpCas9	negative selection	9883177
40276061	40276084	15	-	27869803	PATU8988S	viability after 31 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	0.29273230055633087	[524]	[222,298,NaN]	3	hSpCas9	negative selection	9883178
40264947	40264970	15	+	27869803	HPAFII	viability after 35 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	0.9468390491232308	[149]	[80,219,NaN]	6	hSpCas9	negative selection	9965622
40266064	40266087	15	+	27869803	HPAFII	viability after 35 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.8622028524202745	[915]	[216,297,NaN]	-5	hSpCas9	negative selection	9965623
40272574	40272597	15	-	27869803	HPAFII	viability after 35 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	1.0676078903585555	[161]	[193,146,NaN]	7	hSpCas9	negative selection	9965624
40272880	40272903	15	+	27869803	HPAFII	viability after 35 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.2515696768378408	[727]	[278,343,NaN]	-1	hSpCas9	negative selection	9965625
40274214	40274237	15	-	27869803	HPAFII	viability after 35 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.10640330499006967	[85]	[20,75,NaN]	0	hSpCas9	negative selection	9965626
40276061	40276084	15	-	27869803	HPAFII	viability after 35 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	0.14839320040013618	[248]	[150,126,NaN]	0	hSpCas9	negative selection	9965627
40264947	40264970	15	+	27869803	HPAFII	viability after 31 days	GGACCCTTCGCGAATCACACGGG	PAK6	ENSG00000137843	0.7451997180994432	[149]	[109,174,NaN]	5	hSpCas9	negative selection	10048071
40266064	40266087	15	+	27869803	HPAFII	viability after 31 days	CTCTACCTCAGCTGCAACGGGGG	PAK6	ENSG00000137843	-0.688129268270046	[915]	[353,280,NaN]	-4	hSpCas9	negative selection	10048072
40272574	40272597	15	-	27869803	HPAFII	viability after 31 days	CGTAGCTGTCCAGCAGCAGCCGG	PAK6	ENSG00000137843	0.5390078531500984	[161]	[111,153,NaN]	4	hSpCas9	negative selection	10048073
40272880	40272903	15	+	27869803	HPAFII	viability after 31 days	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.2914906840006528	[727]	[340,325,NaN]	-2	hSpCas9	negative selection	10048074
40274214	40274237	15	-	27869803	HPAFII	viability after 31 days	AGCCTCTTCATGGCTTGCACTGG	PAK6	ENSG00000137843	0.772054009242758	[85]	[35,132,NaN]	5	hSpCas9	negative selection	10048075
40276061	40276084	15	-	27869803	HPAFII	viability after 31 days	AGGTCTGCTTTCGGTAGAGCTGG	PAK6	ENSG00000137843	0.03331266527521359	[248]	[131,154,NaN]	0	hSpCas9	negative selection	10048076
40272880	40272903	15	+	28162770	P31FUJ	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.050369846990491324	[248]	[302]	0	hSpCas9	negative selection	10206472
40264968	40264991	15	+	28162770	P31FUJ	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-0.11695387572785898	[597]	[647]	-1	hSpCas9	negative selection	10206473
40266056	40266079	15	-	28162770	P31FUJ	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-1.146645560664664	[129]	[68]	-7	hSpCas9	negative selection	10206474
40266095	40266118	15	+	28162770	P31FUJ	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	0.07914180190036169	[173]	[215]	0	hSpCas9	negative selection	10206475
40266392	40266415	15	+	28162770	P31FUJ	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	-3.298891394872151	[66]	[7]	-9	hSpCas9	negative selection	10206476
40272643	40272666	15	+	28162770	P31FUJ	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	-0.5223088216093636	[175]	[143]	-4	hSpCas9	negative selection	10206477
40273366	40273389	15	-	28162770	P31FUJ	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	-0.37030572816431384	[54]	[49]	-3	hSpCas9	negative selection	10206478
40274193	40274216	15	-	28162770	P31FUJ	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-0.003320358291611397	[231]	[271]	0	hSpCas9	negative selection	10206479
40264907	40264930	15	+	28162770	P31FUJ	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.05703980625901761	[390]	[477]	0	hSpCas9	negative selection	10206480
40264940	40264963	15	-	28162770	P31FUJ	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	-0.16037373124938203	[504]	[530]	-1	hSpCas9	negative selection	10206481
40272880	40272903	15	+	28162770	TF1	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	NaN	[NaN]	[414]	1	hSpCas9	negative selection	10375838
40264968	40264991	15	+	28162770	TF1	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	NaN	[NaN]	[555]	1	hSpCas9	negative selection	10375839
40266056	40266079	15	-	28162770	TF1	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10375840
40266095	40266118	15	+	28162770	TF1	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	NaN	[NaN]	[239]	1	hSpCas9	negative selection	10375841
40266392	40266415	15	+	28162770	TF1	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10375842
40272643	40272666	15	+	28162770	TF1	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	NaN	[NaN]	[217]	1	hSpCas9	negative selection	10375843
40273366	40273389	15	-	28162770	TF1	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10375844
40274193	40274216	15	-	28162770	TF1	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10375845
40264907	40264930	15	+	28162770	TF1	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	NaN	[NaN]	[407]	1	hSpCas9	negative selection	10375846
40264940	40264963	15	-	28162770	TF1	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	NaN	[NaN]	[471]	1	hSpCas9	negative selection	10375847
40272880	40272903	15	+	28162770	SKM1	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.145937092745696	[90]	[177]	1	hSpCas9	negative selection	10545204
40264968	40264991	15	+	28162770	SKM1	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-0.356778441574945	[112]	[155]	-3	hSpCas9	negative selection	10545205
40266056	40266079	15	-	28162770	SKM1	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	0.06552357271958198	[39]	[73]	0	hSpCas9	negative selection	10545206
40266095	40266118	15	+	28162770	SKM1	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	-0.15215029971433625	[43]	[69]	-1	hSpCas9	negative selection	10545207
40266392	40266415	15	+	28162770	SKM1	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	-0.4069641987431616	[14]	[19]	-3	hSpCas9	negative selection	10545208
40272643	40272666	15	+	28162770	SKM1	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	0.6942480526151364	[42]	[122]	6	hSpCas9	negative selection	10545209
40273366	40273389	15	-	28162770	SKM1	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	1.4190064014817896	[10]	[51]	9	hSpCas9	negative selection	10545210
40274193	40274216	15	-	28162770	SKM1	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	0.7529071380352278	[47]	[142]	7	hSpCas9	negative selection	10545211
40264907	40264930	15	+	28162770	SKM1	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.31103977874462607	[79]	[113]	-3	hSpCas9	negative selection	10545212
40264940	40264963	15	-	28162770	SKM1	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.23364633152790892	[88]	[184]	2	hSpCas9	negative selection	10545213
40272880	40272903	15	+	28162770	SKM1	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.145937092745696	[90]	[177]	1	hSpCas9	negative selection	10714570
40264968	40264991	15	+	28162770	SKM1	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-0.356778441574945	[112]	[155]	-3	hSpCas9	negative selection	10714571
40266056	40266079	15	-	28162770	SKM1	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	0.06552357271958198	[39]	[73]	0	hSpCas9	negative selection	10714572
40266095	40266118	15	+	28162770	SKM1	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	-0.15215029971433625	[43]	[69]	-1	hSpCas9	negative selection	10714573
40266392	40266415	15	+	28162770	SKM1	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	-0.4069641987431616	[14]	[19]	-3	hSpCas9	negative selection	10714574
40272643	40272666	15	+	28162770	SKM1	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	0.6942480526151364	[42]	[122]	6	hSpCas9	negative selection	10714575
40273366	40273389	15	-	28162770	SKM1	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	1.4190064014817896	[10]	[51]	9	hSpCas9	negative selection	10714576
40274193	40274216	15	-	28162770	SKM1	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	0.7529071380352278	[47]	[142]	7	hSpCas9	negative selection	10714577
40264907	40264930	15	+	28162770	SKM1	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.31103977874462607	[79]	[113]	-3	hSpCas9	negative selection	10714578
40264940	40264963	15	-	28162770	SKM1	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.23364633152790892	[88]	[184]	2	hSpCas9	negative selection	10714579
40272880	40272903	15	+	28162770	PL21	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.38120517353683303	[343]	[194]	3	hSpCas9	negative selection	10883936
40264968	40264991	15	+	28162770	PL21	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	0.37175099255951916	[379]	[213]	3	hSpCas9	negative selection	10883937
40266056	40266079	15	-	28162770	PL21	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	0.40572374813921397	[110]	[63]	3	hSpCas9	negative selection	10883938
40266095	40266118	15	+	28162770	PL21	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	-1.0754948281241072	[183]	[37]	-6	hSpCas9	negative selection	10883939
40266392	40266415	15	+	28162770	PL21	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	-1.1408973033457466	[75]	[14]	-6	hSpCas9	negative selection	10883940
40272643	40272666	15	+	28162770	PL21	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	-1.1702288354557953	[211]	[40]	-7	hSpCas9	negative selection	10883941
40273366	40273389	15	-	28162770	PL21	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	0.4017734756589708	[39]	[22]	3	hSpCas9	negative selection	10883942
40274193	40274216	15	-	28162770	PL21	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	0.8848344617956929	[162]	[130]	7	hSpCas9	negative selection	10883943
40264907	40264930	15	+	28162770	PL21	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.37243916177600367	[347]	[116]	-3	hSpCas9	negative selection	10883944
40264940	40264963	15	-	28162770	PL21	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.48854367523714703	[356]	[217]	4	hSpCas9	negative selection	10883945
40272880	40272903	15	+	28162770	P31FUJ	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.050369846990491324	[248]	[302]	0	hSpCas9	negative selection	11053302
40264968	40264991	15	+	28162770	P31FUJ	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-0.11695387572785898	[597]	[647]	-1	hSpCas9	negative selection	11053303
40266056	40266079	15	-	28162770	P31FUJ	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-1.146645560664664	[129]	[68]	-7	hSpCas9	negative selection	11053304
40266095	40266118	15	+	28162770	P31FUJ	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	0.07914180190036169	[173]	[215]	0	hSpCas9	negative selection	11053305
40266392	40266415	15	+	28162770	P31FUJ	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	-3.298891394872151	[66]	[7]	-9	hSpCas9	negative selection	11053306
40272643	40272666	15	+	28162770	P31FUJ	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	-0.5223088216093636	[175]	[143]	-4	hSpCas9	negative selection	11053307
40273366	40273389	15	-	28162770	P31FUJ	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	-0.37030572816431384	[54]	[49]	-3	hSpCas9	negative selection	11053308
40274193	40274216	15	-	28162770	P31FUJ	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-0.003320358291611397	[231]	[271]	0	hSpCas9	negative selection	11053309
40264907	40264930	15	+	28162770	P31FUJ	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.05703980625901761	[390]	[477]	0	hSpCas9	negative selection	11053310
40264940	40264963	15	-	28162770	P31FUJ	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	-0.16037373124938203	[504]	[530]	-1	hSpCas9	negative selection	11053311
40272880	40272903	15	+	28162770	OCIAML5	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.559359674862468	[149]	[398]	5	hSpCas9	negative selection	11222668
40264968	40264991	15	+	28162770	OCIAML5	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-0.09580963808903076	[311]	[526]	0	hSpCas9	negative selection	11222669
40266056	40266079	15	-	28162770	OCIAML5	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-0.6334262843886567	[54]	[63]	-4	hSpCas9	negative selection	11222670
40266095	40266118	15	+	28162770	OCIAML5	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	-0.43400137888758505	[118]	[158]	-3	hSpCas9	negative selection	11222671
40266392	40266415	15	+	28162770	OCIAML5	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	2.406667697536171	[13]	[133]	9	hSpCas9	negative selection	11222672
40272643	40272666	15	+	28162770	OCIAML5	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	-0.01669727263679635	[101]	[181]	0	hSpCas9	negative selection	11222673
40273366	40273389	15	-	28162770	OCIAML5	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	-1.2506159473542717	[28]	[21]	-6	hSpCas9	negative selection	11222674
40274193	40274216	15	-	28162770	OCIAML5	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	0.06849896164159813	[83]	[158]	0	hSpCas9	negative selection	11222675
40264907	40264930	15	+	28162770	OCIAML5	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.37881731136609065	[241]	[567]	3	hSpCas9	negative selection	11222676
40264940	40264963	15	-	28162770	OCIAML5	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.7882389637009343	[178]	[557]	7	hSpCas9	negative selection	11222677
40272880	40272903	15	+	28162770	EOL1	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.5248001433162861	[656]	[497]	5	hSpCas9	negative selection	11392034
40264968	40264991	15	+	28162770	EOL1	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	0.9833371027781398	[552]	[575]	8	hSpCas9	negative selection	11392035
40266056	40266079	15	-	28162770	EOL1	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-0.06464547347288263	[265]	[133]	0	hSpCas9	negative selection	11392036
40266095	40266118	15	+	28162770	EOL1	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	-0.16488731201140985	[365]	[171]	-1	hSpCas9	negative selection	11392037
40266392	40266415	15	+	28162770	EOL1	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	0.624987489711627	[95]	[77]	5	hSpCas9	negative selection	11392038
40272643	40272666	15	+	28162770	EOL1	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	-0.18236743234597746	[447]	[207]	-1	hSpCas9	negative selection	11392039
40273366	40273389	15	-	28162770	EOL1	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	-1.5779525689586489	[50]	[8]	-7	hSpCas9	negative selection	11392040
40274193	40274216	15	-	28162770	EOL1	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	0.7681026841671392	[252]	[226]	6	hSpCas9	negative selection	11392041
40264907	40264930	15	+	28162770	EOL1	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.03855264561793631	[385]	[197]	0	hSpCas9	negative selection	11392042
40264940	40264963	15	-	28162770	EOL1	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.9301943347116766	[509]	[511]	7	hSpCas9	negative selection	11392043
40272880	40272903	15	+	28162770	MOLM13	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.4742871527427295	[449]	[451]	3	hSpCas9	negative selection	11561400
40264968	40264991	15	+	28162770	MOLM13	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-0.051318673692862804	[578]	[403]	0	hSpCas9	negative selection	11561401
40266056	40266079	15	-	28162770	MOLM13	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-0.6549673662409545	[195]	[89]	-4	hSpCas9	negative selection	11561402
40266095	40266118	15	+	28162770	MOLM13	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	0.09443098601713437	[227]	[175]	0	hSpCas9	negative selection	11561403
40266392	40266415	15	+	28162770	MOLM13	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	1.5060245104313499	[55]	[114]	9	hSpCas9	negative selection	11561404
40272643	40272666	15	+	28162770	MOLM13	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	0.5669975265575034	[224]	[240]	4	hSpCas9	negative selection	11561405
40273366	40273389	15	-	28162770	MOLM13	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	-2.5470609599213923	[96]	[11]	-8	hSpCas9	negative selection	11561406
40274193	40274216	15	-	28162770	MOLM13	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-0.11465451837393384	[297]	[198]	0	hSpCas9	negative selection	11561407
40264907	40264930	15	+	28162770	MOLM13	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	0.08139128847966126	[633]	[484]	0	hSpCas9	negative selection	11561408
40264940	40264963	15	-	28162770	MOLM13	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.7505666603494472	[461]	[561]	5	hSpCas9	negative selection	11561409
40272880	40272903	15	+	28162770	HEL	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	1.242274133808786	[393]	[596]	9	hSpCas9	negative selection	11730766
40264968	40264991	15	+	28162770	HEL	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	0.36791712955877554	[466]	[385]	3	hSpCas9	negative selection	11730767
40266056	40266079	15	-	28162770	HEL	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-0.03168529609713644	[157]	[98]	0	hSpCas9	negative selection	11730768
40266095	40266118	15	+	28162770	HEL	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	0.015397729008648942	[189]	[122]	0	hSpCas9	negative selection	11730769
40266392	40266415	15	+	28162770	HEL	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	-0.8682230872770225	[56]	[19]	-5	hSpCas9	negative selection	11730770
40272643	40272666	15	+	28162770	HEL	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	-0.5478398406602977	[298]	[130]	-4	hSpCas9	negative selection	11730771
40273366	40273389	15	-	28162770	HEL	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	-0.4045668827779998	[61]	[29]	-3	hSpCas9	negative selection	11730772
40274193	40274216	15	-	28162770	HEL	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-0.3283484760844044	[246]	[125]	-2	hSpCas9	negative selection	11730773
40264907	40264930	15	+	28162770	HEL	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.32059245795224633	[504]	[258]	-2	hSpCas9	negative selection	11730774
40264940	40264963	15	-	28162770	HEL	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.20483722436977625	[423]	[312]	1	hSpCas9	negative selection	11730775
40272880	40272903	15	+	28162770	MV411	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.28491225620143834	[341]	[350]	2	hSpCas9	negative selection	11900132
40264968	40264991	15	+	28162770	MV411	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-0.012264994353270442	[345]	[288]	0	hSpCas9	negative selection	11900133
40266056	40266079	15	-	28162770	MV411	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-0.6948469513609373	[97]	[50]	-5	hSpCas9	negative selection	11900134
40266095	40266118	15	+	28162770	MV411	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	0.170475568967891	[153]	[145]	1	hSpCas9	negative selection	11900135
40266392	40266415	15	+	28162770	MV411	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	-0.1675999484960684	[63]	[47]	-1	hSpCas9	negative selection	11900136
40272643	40272666	15	+	28162770	MV411	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	-0.1981218932729645	[206]	[151]	-1	hSpCas9	negative selection	11900137
40273366	40273389	15	-	28162770	MV411	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	0.632727706667567	[48]	[63]	6	hSpCas9	negative selection	11900138
40274193	40274216	15	-	28162770	MV411	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-1.5745641472392302	[197]	[55]	-7	hSpCas9	negative selection	11900139
40264907	40264930	15	+	28162770	MV411	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.10713530723217418	[256]	[200]	-1	hSpCas9	negative selection	11900140
40264940	40264963	15	-	28162770	MV411	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.28043582634023223	[388]	[397]	2	hSpCas9	negative selection	11900141
40272880	40272903	15	+	28162770	MONOMAC1	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.2725270466438172	[254]	[241]	-2	hSpCas9	negative selection	12069498
40264968	40264991	15	+	28162770	MONOMAC1	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	-0.5618011398571738	[281]	[218]	-5	hSpCas9	negative selection	12069499
40266056	40266079	15	-	28162770	MONOMAC1	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-0.6356098607991865	[102]	[75]	-5	hSpCas9	negative selection	12069500
40266095	40266118	15	+	28162770	MONOMAC1	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	2.4883275506194398	[110]	[713]	9	hSpCas9	negative selection	12069501
40266392	40266415	15	+	28162770	MONOMAC1	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	1.3693099754942555	[25]	[76]	9	hSpCas9	negative selection	12069502
40272643	40272666	15	+	28162770	MONOMAC1	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	-0.7310154190619049	[138]	[95]	-5	hSpCas9	negative selection	12069503
40273366	40273389	15	-	28162770	MONOMAC1	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	-3.0043917691171576	[34]	[4]	-9	hSpCas9	negative selection	12069504
40274193	40274216	15	-	28162770	MONOMAC1	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-0.9963394968224246	[133]	[76]	-7	hSpCas9	negative selection	12069505
40264907	40264930	15	+	28162770	MONOMAC1	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.27035352470247453	[221]	[210]	-2	hSpCas9	negative selection	12069506
40264940	40264963	15	-	28162770	MONOMAC1	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.4701740654213169	[249]	[396]	4	hSpCas9	negative selection	12069507
40272880	40272903	15	+	28162770	OCIAML2	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	0.8643544224706475	[65]	[665]	8	hSpCas9	negative selection	12238864
40264968	40264991	15	+	28162770	OCIAML2	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	0.6491094190319343	[51]	[451]	6	hSpCas9	negative selection	12238865
40266056	40266079	15	-	28162770	OCIAML2	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-1.262521629911961	[28]	[66]	-7	hSpCas9	negative selection	12238866
40266095	40266118	15	+	28162770	OCIAML2	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	-0.16684907706505828	[31]	[157]	-1	hSpCas9	negative selection	12238867
40266392	40266415	15	+	28162770	OCIAML2	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	0.8830071293725394	[8]	[91]	8	hSpCas9	negative selection	12238868
40272643	40272666	15	+	28162770	OCIAML2	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	0.15685729212555202	[38]	[240]	1	hSpCas9	negative selection	12238869
40273366	40273389	15	-	28162770	OCIAML2	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	0.014797001928080533	[9]	[55]	0	hSpCas9	negative selection	12238870
40274193	40274216	15	-	28162770	OCIAML2	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-0.5124500009367884	[34]	[135]	-4	hSpCas9	negative selection	12238871
40264907	40264930	15	+	28162770	OCIAML2	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.008628846992730699	[50]	[280]	0	hSpCas9	negative selection	12238872
40264940	40264963	15	-	28162770	OCIAML2	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	0.030621969089763112	[67]	[384]	0	hSpCas9	negative selection	12238873
40272880	40272903	15	+	28162770	OCIAML3	viability	GGACTACCAGCACTTCAACGTGG	PAK6	ENSG00000137843	-0.4823622844952541	[86]	[187]	-4	hSpCas9	negative selection	12408230
40264968	40264991	15	+	28162770	OCIAML3	viability	GGTGCAGCTCCAGCCCATGAAGG	PAK6	ENSG00000137843	0.5318041129843516	[106]	[466]	5	hSpCas9	negative selection	12408231
40266056	40266079	15	-	28162770	OCIAML3	viability	GCAGCTGAGGTAGAGGCCGTGGG	PAK6	ENSG00000137843	-0.4593581136293814	[45]	[100]	-4	hSpCas9	negative selection	12408232
40266095	40266118	15	+	28162770	OCIAML3	viability	CAGGCCACAAGCAGATGCCGTGG	PAK6	ENSG00000137843	-0.31602289302439807	[39]	[96]	-2	hSpCas9	negative selection	12408233
40266392	40266415	15	+	28162770	OCIAML3	viability	GGGAGAGCAGCCTGAAGCGCAGG	PAK6	ENSG00000137843	-1.206984517214916	[12]	[16]	-7	hSpCas9	negative selection	12408234
40272643	40272666	15	+	28162770	OCIAML3	viability	GAAGCACTCGGGCCGCCAGGTGG	PAK6	ENSG00000137843	-0.6071830290718964	[54]	[108]	-4	hSpCas9	negative selection	12408235
40273366	40273389	15	-	28162770	OCIAML3	viability	CAGCACAGCCTCACACACAGTGG	PAK6	ENSG00000137843	1.9420452599160463	[4]	[57]	9	hSpCas9	negative selection	12408236
40274193	40274216	15	-	28162770	OCIAML3	viability	GGGGAGTCACTGAAGTACGGTGG	PAK6	ENSG00000137843	-0.39347465295145456	[56]	[130]	-3	hSpCas9	negative selection	12408237
40264907	40264930	15	+	28162770	OCIAML3	viability	AGAACATCCTGGACACACTGCGG	PAK6	ENSG00000137843	-0.22973325472720607	[93]	[241]	-2	hSpCas9	negative selection	12408238
40264940	40264963	15	-	28162770	OCIAML3	viability	GATTCGCGAAGGGTCCACCACGG	PAK6	ENSG00000137843	-0.1272265659513211	[88]	[245]	-1	hSpCas9	negative selection	12408239