| 80247298 | 80247321 | 18 | + | 26472758 | Jiyoye | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.12964140597696439 | [239] | [197] | 1 | hSpCas9 | negative selection | 116012 | 80247298 | 80247321 | 18 | + | 26472758 | KBM7 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.6781735275861487 | [661,633] | [267,121] | -5 | hSpCas9 | negative selection | 307130 | 80247298 | 80247321 | 18 | + | 26472758 | Raji | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.08272148113933042 | [353] | [86] | 0 | hSpCas9 | negative selection | 498248 | 80247298 | 80247321 | 18 | + | 26472758 | K562 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.27053405180696666 | [542] | [379] | -2 | hSpCas9 | negative selection | 689366 | 80160190 | 80160213 | 18 | + | 26627737 | DLD1 | viability | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 0.007053485693022443 | [1029] | [242,422,310] | 0 | hSpCas9 | negative selection | 802157 | 80160448 | 80160471 | 18 | - | 26627737 | DLD1 | viability | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.26910538202331635 | [250] | [142,122,28] | 2 | hSpCas9 | negative selection | 802158 | 80183119 | 80183142 | 18 | + | 26627737 | DLD1 | viability | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 0.410019828770134 | [173] | [53,104,60] | 4 | hSpCas9 | negative selection | 802159 | 80247276 | 80247299 | 18 | - | 26627737 | DLD1 | viability | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -0.5361370502141778 | [1488] | [408,287,271] | -5 | hSpCas9 | negative selection | 802160 | 80247298 | 80247321 | 18 | + | 26627737 | DLD1 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.11730373051783222 | [339] | [20,165,154] | 1 | hSpCas9 | negative selection | 802161 | 80160190 | 80160213 | 18 | + | 26627737 | GBM cells | viability after 5 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 0.17193236929210154 | [335] | [192,212] | 2 | hSpCas9 | negative selection | 884472 | 80160448 | 80160471 | 18 | - | 26627737 | GBM cells | viability after 5 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.0034444583569922527 | [172] | [90,94] | 0 | hSpCas9 | negative selection | 884473 | 80183119 | 80183142 | 18 | + | 26627737 | GBM cells | viability after 5 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | -0.5970436197767256 | [164] | [61,54] | -7 | hSpCas9 | negative selection | 884474 | 80247276 | 80247299 | 18 | - | 26627737 | GBM cells | viability after 5 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.02826242270849444 | [628] | [316,370] | 0 | hSpCas9 | negative selection | 884475 | 80247298 | 80247321 | 18 | + | 26627737 | GBM cells | viability after 5 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.9180226978333901 | [74] | [42,108] | 9 | hSpCas9 | negative selection | 884476 | 80160190 | 80160213 | 18 | + | 26627737 | GBM cells | viability after 13 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 0.3561555416946286 | [335] | [250,218] | 4 | hSpCas9 | negative selection | 966787 | 80160448 | 80160471 | 18 | - | 26627737 | GBM cells | viability after 13 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.18877683347628793 | [172] | [99,67] | -2 | hSpCas9 | negative selection | 966788 | 80183119 | 80183142 | 18 | + | 26627737 | GBM cells | viability after 13 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | -1.1107141693472862 | [164] | [57,27] | -8 | hSpCas9 | negative selection | 966789 | 80247276 | 80247299 | 18 | - | 26627737 | GBM cells | viability after 13 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -0.20561060557479638 | [628] | [258,325] | -2 | hSpCas9 | negative selection | 966790 | 80247298 | 80247321 | 18 | + | 26627737 | GBM cells | viability after 13 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 1.6102157111906805 | [74] | [110,134] | 9 | hSpCas9 | negative selection | 966791 | 80160190 | 80160213 | 18 | + | 26627737 | GBM cells | viability after 21 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 0.06853038874908202 | [335] | [204,178] | 0 | hSpCas9 | negative selection | 1049102 | 80160448 | 80160471 | 18 | - | 26627737 | GBM cells | viability after 21 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.6403088310083439 | [172] | [64,55] | -5 | hSpCas9 | negative selection | 1049103 | 80183119 | 80183142 | 18 | + | 26627737 | GBM cells | viability after 21 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | -0.48208698407266104 | [164] | [59,67] | -4 | hSpCas9 | negative selection | 1049104 | 80247276 | 80247299 | 18 | - | 26627737 | GBM cells | viability after 21 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.18025223512360156 | [628] | [405,369] | 2 | hSpCas9 | negative selection | 1049105 | 80247298 | 80247321 | 18 | + | 26627737 | GBM cells | viability after 21 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 1.6230858860612831 | [74] | [136,114] | 9 | hSpCas9 | negative selection | 1049106 | 80160190 | 80160213 | 18 | + | 26627737 | RPE1 | viability after 9 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -1.2735823156017432 | [1678] | [116,346] | -7 | hSpCas9 | negative selection | 1131417 | 80160448 | 80160471 | 18 | - | 26627737 | RPE1 | viability after 9 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -1.4863209398141228 | [692] | [14,157] | -8 | hSpCas9 | negative selection | 1131418 | 80183119 | 80183142 | 18 | + | 26627737 | RPE1 | viability after 9 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | -0.09178562522224892 | [653] | [192,190] | 0 | hSpCas9 | negative selection | 1131419 | 80247276 | 80247299 | 18 | - | 26627737 | RPE1 | viability after 9 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.17256034511882046 | [1860] | [667,641] | 1 | hSpCas9 | negative selection | 1131420 | 80247298 | 80247321 | 18 | + | 26627737 | RPE1 | viability after 9 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 5.997882526999679 | [1] | [15,70] | 9 | hSpCas9 | negative selection | 1131421 | 80160190 | 80160213 | 18 | + | 26627737 | RPE1 | viability after 12 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -1.666657404406097 | [1678] | [127,156] | -8 | hSpCas9 | negative selection | 1213732 | 80160448 | 80160471 | 18 | - | 26627737 | RPE1 | viability after 12 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -1.2504495967036642 | [692] | [137,14] | -7 | hSpCas9 | negative selection | 1213733 | 80183119 | 80183142 | 18 | + | 26627737 | RPE1 | viability after 12 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 0.3293742518454927 | [653] | [229,210] | 2 | hSpCas9 | negative selection | 1213734 | 80247276 | 80247299 | 18 | - | 26627737 | RPE1 | viability after 12 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -0.2480745053196176 | [1860] | [369,474] | -2 | hSpCas9 | negative selection | 1213735 | 80247298 | 80247321 | 18 | + | 26627737 | RPE1 | viability after 12 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 5.981147515528937 | [1] | [48,17] | 9 | hSpCas9 | negative selection | 1213736 | 80160190 | 80160213 | 18 | + | 26627737 | RPE1 | viability after 15 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -0.5587555830879367 | [1678] | [353,291] | -4 | hSpCas9 | negative selection | 1296047 | 80160448 | 80160471 | 18 | - | 26627737 | RPE1 | viability after 15 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -1.1942879193974119 | [692] | [19,148] | -6 | hSpCas9 | negative selection | 1296048 | 80183119 | 80183142 | 18 | + | 26627737 | RPE1 | viability after 15 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 0.14347332770579016 | [653] | [212,195] | 0 | hSpCas9 | negative selection | 1296049 | 80247276 | 80247299 | 18 | - | 26627737 | RPE1 | viability after 15 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -0.24436026738540528 | [1860] | [589,303] | -1 | hSpCas9 | negative selection | 1296050 | 80247298 | 80247321 | 18 | + | 26627737 | RPE1 | viability after 15 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.8217488738718943 | [1] | [0,0] | 5 | hSpCas9 | negative selection | 1296051 | 80160190 | 80160213 | 18 | + | 26627737 | RPE1 | viability after 18 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -2.5849060448782573 | [1678] | [46,105] | -8 | hSpCas9 | negative selection | 1378362 | 80160448 | 80160471 | 18 | - | 26627737 | RPE1 | viability after 18 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -1.2983962199291474 | [692] | [47,105] | -7 | hSpCas9 | negative selection | 1378363 | 80183119 | 80183142 | 18 | + | 26627737 | RPE1 | viability after 18 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 0.11795407729973251 | [653] | [206,174] | 0 | hSpCas9 | negative selection | 1378364 | 80247276 | 80247299 | 18 | - | 26627737 | RPE1 | viability after 18 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -0.11492057730478944 | [1860] | [529,392] | 0 | hSpCas9 | negative selection | 1378365 | 80247298 | 80247321 | 18 | + | 26627737 | RPE1 | viability after 18 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 5.186073472502972 | [1] | [23,14] | 9 | hSpCas9 | negative selection | 1378366 | 80160190 | 80160213 | 18 | + | 26627737 | HeLa | viability after 8 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 1.7527761842866263 | [257] | [506,361,299] | 9 | hSpCas9 | negative selection | 1460677 | 80160448 | 80160471 | 18 | - | 26627737 | HeLa | viability after 8 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.725916615874371 | [176] | [254,127,33] | 6 | hSpCas9 | negative selection | 1460678 | 80183119 | 80183142 | 18 | + | 26627737 | HeLa | viability after 8 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 1.695606872309935 | [91] | [178,107,113] | 9 | hSpCas9 | negative selection | 1460679 | 80247276 | 80247299 | 18 | - | 26627737 | HeLa | viability after 8 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.9121299989845802 | [471] | [735,181,322] | 7 | hSpCas9 | negative selection | 1460680 | 80247298 | 80247321 | 18 | + | 26627737 | HeLa | viability after 8 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.7914446222672065 | [172] | [58,32,41] | -7 | hSpCas9 | negative selection | 1460681 | 80160190 | 80160213 | 18 | + | 26627737 | HeLa | viability after 12 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 1.688096835621273 | [257] | [405,206,433] | 9 | hSpCas9 | negative selection | 1542992 | 80160448 | 80160471 | 18 | - | 26627737 | HeLa | viability after 12 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.556287808989993 | [176] | [228,52,49] | 4 | hSpCas9 | negative selection | 1542993 | 80183119 | 80183142 | 18 | + | 26627737 | HeLa | viability after 12 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 1.7343628849096355 | [91] | [114,165,93] | 9 | hSpCas9 | negative selection | 1542994 | 80247276 | 80247299 | 18 | - | 26627737 | HeLa | viability after 12 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 1.215955212246489 | [471] | [682,292,406] | 8 | hSpCas9 | negative selection | 1542995 | 80247298 | 80247321 | 18 | + | 26627737 | HeLa | viability after 12 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.2920625904222014 | [172] | [123,11,45] | -3 | hSpCas9 | negative selection | 1542996 | 80160190 | 80160213 | 18 | + | 26627737 | HeLa | viability after 15 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 0.8367796333046352 | [257] | [128,180,258] | 6 | hSpCas9 | negative selection | 1625307 | 80160448 | 80160471 | 18 | - | 26627737 | HeLa | viability after 15 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 1.3665748959076214 | [176] | [189,197,167] | 8 | hSpCas9 | negative selection | 1625308 | 80183119 | 80183142 | 18 | + | 26627737 | HeLa | viability after 15 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 2.094184135801249 | [91] | [156,244,70] | 9 | hSpCas9 | negative selection | 1625309 | 80247276 | 80247299 | 18 | - | 26627737 | HeLa | viability after 15 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.9536058758101117 | [471] | [261,336,530] | 7 | hSpCas9 | negative selection | 1625310 | 80247298 | 80247321 | 18 | + | 26627737 | HeLa | viability after 15 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.31832253382107445 | [172] | [130,78,49] | 2 | hSpCas9 | negative selection | 1625311 | 80160190 | 80160213 | 18 | + | 26627737 | HeLa | viability after 18 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 0.8499525374975482 | [257] | [88,150,258] | 6 | hSpCas9 | negative selection | 1707622 | 80160448 | 80160471 | 18 | - | 26627737 | HeLa | viability after 18 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 1.4011134368328424 | [176] | [124,177,167] | 8 | hSpCas9 | negative selection | 1707623 | 80183119 | 80183142 | 18 | + | 26627737 | HeLa | viability after 18 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 2.13607615479077 | [91] | [111,205,70] | 9 | hSpCas9 | negative selection | 1707624 | 80247276 | 80247299 | 18 | - | 26627737 | HeLa | viability after 18 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.9819664446802795 | [471] | [182,287,530] | 7 | hSpCas9 | negative selection | 1707625 | 80247298 | 80247321 | 18 | + | 26627737 | HeLa | viability after 18 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.3113124651529986 | [172] | [88,62,49] | 2 | hSpCas9 | negative selection | 1707626 | 80160190 | 80160213 | 18 | + | 26627737 | HCT116 | viability after 6 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 0.4586261763873012 | [1120] | [499,99] | 2 | hSpCas9 | negative selection | 1789937 | 80160448 | 80160471 | 18 | - | 26627737 | HCT116 | viability after 6 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.563021122918063 | [391] | [237,9] | 3 | hSpCas9 | negative selection | 1789938 | 80183119 | 80183142 | 18 | + | 26627737 | HCT116 | viability after 6 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 0.16698619640982737 | [140] | [40,15] | 0 | hSpCas9 | negative selection | 1789939 | 80247276 | 80247299 | 18 | - | 26627737 | HCT116 | viability after 6 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 1.025721404482928 | [1534] | [237,630] | 5 | hSpCas9 | negative selection | 1789940 | 80247298 | 80247321 | 18 | + | 26627737 | HCT116 | viability after 6 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -3.8017015197002655 | [411] | [3,4] | -9 | hSpCas9 | negative selection | 1789941 | 80160190 | 80160213 | 18 | + | 26627737 | HCT116 | viability after 8 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -0.3251051969175114 | [621] | [370,218,232] | -4 | hSpCas9 | negative selection | 1872252 | 80160448 | 80160471 | 18 | - | 26627737 | HCT116 | viability after 8 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.25009702418885876 | [243] | [45,99,190] | -3 | hSpCas9 | negative selection | 1872253 | 80183119 | 80183142 | 18 | + | 26627737 | HCT116 | viability after 8 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 0.13031662222257812 | [160] | [59,162,67] | 1 | hSpCas9 | negative selection | 1872254 | 80247276 | 80247299 | 18 | - | 26627737 | HCT116 | viability after 8 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.6597249772913067 | [521] | [352,438,567] | 6 | hSpCas9 | negative selection | 1872255 | 80247298 | 80247321 | 18 | + | 26627737 | HCT116 | viability after 8 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -1.4130808044325633 | [298] | [32,82,68] | -9 | hSpCas9 | negative selection | 1872256 | 80160190 | 80160213 | 18 | + | 26627737 | HCT116 | viability after 9 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 0.7847142292759215 | [1120] | [804,286] | 5 | hSpCas9 | negative selection | 1954567 | 80160448 | 80160471 | 18 | - | 26627737 | HCT116 | viability after 9 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.450379676549701 | [391] | [108,50] | -3 | hSpCas9 | negative selection | 1954568 | 80183119 | 80183142 | 18 | + | 26627737 | HCT116 | viability after 9 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 1.6374685314193989 | [140] | [91,136] | 8 | hSpCas9 | negative selection | 1954569 | 80247276 | 80247299 | 18 | - | 26627737 | HCT116 | viability after 9 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.2234642116201404 | [1534] | [315,606] | 1 | hSpCas9 | negative selection | 1954570 | 80247298 | 80247321 | 18 | + | 26627737 | HCT116 | viability after 9 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -3.5703020329859774 | [411] | [1,14] | -9 | hSpCas9 | negative selection | 1954571 | 80160190 | 80160213 | 18 | + | 26627737 | HCT116 | viability after 12 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 0.07459696485080536 | [621] | [479,230,306] | 0 | hSpCas9 | negative selection | 2036882 | 80160448 | 80160471 | 18 | - | 26627737 | HCT116 | viability after 12 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.5316531049059454 | [243] | [70,19,174] | -5 | hSpCas9 | negative selection | 2036883 | 80183119 | 80183142 | 18 | + | 26627737 | HCT116 | viability after 12 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 0.03750185770056147 | [160] | [74,63,121] | 0 | hSpCas9 | negative selection | 2036884 | 80247276 | 80247299 | 18 | - | 26627737 | HCT116 | viability after 12 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.7338085940084302 | [521] | [545,466,347] | 6 | hSpCas9 | negative selection | 2036885 | 80247298 | 80247321 | 18 | + | 26627737 | HCT116 | viability after 12 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -1.7236580013223857 | [298] | [55,47,37] | -9 | hSpCas9 | negative selection | 2036886 | 80160190 | 80160213 | 18 | + | 26627737 | HCT116 | viability after 15 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -0.12681116225250688 | [621] | [483,226,289] | -1 | hSpCas9 | negative selection | 2119197 | 80160448 | 80160471 | 18 | - | 26627737 | HCT116 | viability after 15 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.2028457580537843 | [243] | [87,56,214] | -2 | hSpCas9 | negative selection | 2119198 | 80183119 | 80183142 | 18 | + | 26627737 | HCT116 | viability after 15 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | -0.38801017343348276 | [160] | [61,84,63] | -4 | hSpCas9 | negative selection | 2119199 | 80247276 | 80247299 | 18 | - | 26627737 | HCT116 | viability after 15 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.5605192923629241 | [521] | [584,337,420] | 5 | hSpCas9 | negative selection | 2119200 | 80247298 | 80247321 | 18 | + | 26627737 | HCT116 | viability after 15 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -1.6580251290151053 | [298] | [31,114,13] | -9 | hSpCas9 | negative selection | 2119201 | 80160190 | 80160213 | 18 | + | 26627737 | HCT116 | viability after 18 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 0.5354982724704413 | [621] | [964,77,280] | 4 | hSpCas9 | negative selection | 2201512 | 80160448 | 80160471 | 18 | - | 26627737 | HCT116 | viability after 18 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.4707359895896273 | [243] | [71,7,184] | -4 | hSpCas9 | negative selection | 2201513 | 80183119 | 80183142 | 18 | + | 26627737 | HCT116 | viability after 18 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 0.07631771681466604 | [160] | [79,75,90] | 0 | hSpCas9 | negative selection | 2201514 | 80247276 | 80247299 | 18 | - | 26627737 | HCT116 | viability after 18 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 1.13575067389858 | [521] | [639,412,622] | 8 | hSpCas9 | negative selection | 2201515 | 80247298 | 80247321 | 18 | + | 26627737 | HCT116 | viability after 18 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.7700127923205579 | [298] | [42,172,29] | -6 | hSpCas9 | negative selection | 2201516 | 80247276 | 80247299 | 18 | - | 24336569 | HL60 | viability | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -1.6034746957221304 | [1277] | [889] | -8 | hSpCas9 | negative selection | 2282662 | 80247291 | 80247314 | 18 | - | 24336569 | HL60 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 0.3656191255807558 | [895] | [2442] | 3 | hSpCas9 | negative selection | 2282663 | 80247298 | 80247321 | 18 | + | 24336569 | HL60 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -1.5183847178061898 | [929] | [686] | -8 | hSpCas9 | negative selection | 2282664 | 80247276 | 80247299 | 18 | - | 24336569 | KBM7 | viability | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -1.1177889838885497 | [731] | [919] | -7 | hSpCas9 | negative selection | 2349839 | 80247291 | 80247314 | 18 | - | 24336569 | KBM7 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 0.13914537467027022 | [1090] | [3276] | 1 | hSpCas9 | negative selection | 2349840 | 80247298 | 80247321 | 18 | + | 24336569 | KBM7 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.9530283271509381 | [652] | [919] | -6 | hSpCas9 | negative selection | 2349841 | 80247424 | 80247447 | 18 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCGGGGCCGGGGCCGGGGCCTGG | PARD6G | ENSG00000178184 | 0.8264823941872752 | [4,0] | [0,0] | 3 | dCas9-VP64 | positive selection | 2401685 | 80164856 | 80164879 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ACAAAGATCACATGCTTCAAAAG | PARD6G | ENSG00000178184 | 0.8342100635498071 | [134,230] | [27,119] | 3 | dCas9-VP64 | positive selection | 2428288 | 80247424 | 80247447 | 18 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCGGGGCCGGGGCCGGGGCCTGG | PARD6G | ENSG00000178184 | -1.4525966344186143 | [120,27] | [8,7] | -9 | dCas9-VP64 | positive selection | 2496940 | 80164856 | 80164879 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ACAAAGATCACATGCTTCAAAAG | PARD6G | ENSG00000178184 | 0.30130477173951054 | [255,211] | [131,58] | 2 | dCas9-VP64 | positive selection | 2523543 | 80247291 | 80247314 | 18 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 0.33287728027804403 | [2,2] | [3,2] | 7 | hSpCas9 | positive selection | 3009640 | 80160458 | 80160481 | 18 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CATCGATGATGGATGATACGGGG | PARD6G | ENSG00000178184 | 0.13398442420397025 | [3,2] | [4,1] | 3 | hSpCas9 | positive selection | 3009641 | 80247299 | 80247322 | 18 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.30599303829207725 | [3,3] | [2,1] | -4 | hSpCas9 | positive selection | 3009642 | 80247291 | 80247314 | 18 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.2380830640184991 | [2,2] | [1,0] | -4 | hSpCas9 | positive selection | 3077498 | 80160458 | 80160481 | 18 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CATCGATGATGGATGATACGGGG | PARD6G | ENSG00000178184 | -0.5023488545448704 | [3,3] | [2,0] | -7 | hSpCas9 | positive selection | 3077499 | 80247299 | 80247322 | 18 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.3938901884714555 | [3,3] | [2,0] | -6 | hSpCas9 | positive selection | 3077500 | 80160345 | 80160368 | | - | 24336571 | A375 | resistance to PLX after 7 days | AGCGTGCGCGTGACCCCGCACGG | PARD6G | ENSG00000178184 | -0.24858872609503546 | [23,23] | [21,17] | -7 | hSpCas9 | positive selection | 3133984 | 80160454 | 80160477 | | - | 24336571 | A375 | resistance to PLX after 7 days | CGTATCATCCATCATCGATGTGG | PARD6G | ENSG00000178184 | 0.34707739761044815 | [14,11] | [17,15] | 8 | hSpCas9 | positive selection | 3133985 | 80160345 | 80160368 | | - | 24336571 | A375 | resistance to PLX after 14 days | AGCGTGCGCGTGACCCCGCACGG | PARD6G | ENSG00000178184 | -0.3600077686750846 | [22,22] | [7,7] | -4 | hSpCas9 | positive selection | 3191777 | 80160454 | 80160477 | | - | 24336571 | A375 | resistance to PLX after 14 days | CGTATCATCCATCATCGATGTGG | PARD6G | ENSG00000178184 | 0.04746394518461122 | [19,8] | [4,8] | 0 | hSpCas9 | positive selection | 3191778 | 80160345 | 80160368 | | - | 24336571 | A375 | viability after 7 days | AGCGTGCGCGTGACCCCGCACGG | PARD6G | ENSG00000178184 | 0.7298286298149144 | [14] | [23,23] | 9 | hSpCas9 | negative selection | 3249570 | 80160454 | 80160477 | | - | 24336571 | A375 | viability after 7 days | CGTATCATCCATCATCGATGTGG | PARD6G | ENSG00000178184 | -0.17537236612786689 | [15] | [14,11] | -2 | hSpCas9 | negative selection | 3249571 | 80160345 | 80160368 | | - | 24336571 | A375 | viability after 14 days | AGCGTGCGCGTGACCCCGCACGG | PARD6G | ENSG00000178184 | 0.683050895620351 | [14] | [22,22] | 8 | hSpCas9 | negative selection | 3307363 | 80160454 | 80160477 | | - | 24336571 | A375 | viability after 14 days | CGTATCATCCATCATCGATGTGG | PARD6G | ENSG00000178184 | -0.03454355477739207 | [15] | [19,8] | 0 | hSpCas9 | negative selection | 3307364 | 80247291 | 80247314 | 18 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 0.25732621144583506 | [127,127] | [0,0] | 1 | hSpCas9 | positive selection | 3384645 | 80247291 | 80247314 | 18 | - | 26780180 | HT29 | viability (Avana library 4 designs) | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 1.82485257123675 | [] | [] | 7 | hSpCas9 | negative selection | 3447679 | 80160457 | 80160480 | 18 | + | 26780180 | HT29 | viability (Avana library 4 designs) | CATCGATGATGGATGATACGGGG | PARD6G | ENSG00000178184 | 2.45809533490534 | [] | [] | 8 | hSpCas9 | negative selection | 3447680 | 80247298 | 80247321 | 18 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 1.5533715736714 | [] | [] | 6 | hSpCas9 | negative selection | 3447681 | 80247298 | 80247321 | 18 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.272873905680242 | [] | [] | 0 | hSpCas9 | negative selection | 3541601 | 80247291 | 80247314 | 18 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -1.23065083025832 | [] | [] | -1 | hSpCas9 | negative selection | 3541602 | 80160457 | 80160480 | 18 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CATCGATGATGGATGATACGGGG | PARD6G | ENSG00000178184 | 3.45711334282498 | [] | [] | 5 | hSpCas9 | negative selection | 3541603 | 80247298 | 80247321 | 18 | + | 26780180 | A375 | viability (Avana lentiGuide) | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 1.75491330720869 | [] | [] | 2 | hSpCas9 | negative selection | 3650260 | 80247291 | 80247314 | 18 | - | 26780180 | A375 | viability (Avana lentiGuide) | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 1.39003364943015 | [] | [] | 1 | hSpCas9 | negative selection | 3650261 | 80160457 | 80160480 | 18 | + | 26780180 | A375 | viability (Avana lentiGuide) | CATCGATGATGGATGATACGGGG | PARD6G | ENSG00000178184 | 0.331763705723235 | [] | [] | 0 | hSpCas9 | negative selection | 3650262 | 80247298 | 80247321 | 18 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.24842930240523903 | [5] | [5,2] | -4 | hSpCas9 | positive selection | 3758919 | 80247291 | 80247314 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.06566903013640817 | [5] | [5,4] | -1 | hSpCas9 | positive selection | 3758920 | 80160457 | 80160480 | 18 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CATCGATGATGGATGATACGGGG | PARD6G | ENSG00000178184 | 0.21521751814714246 | [4] | [5,4] | 6 | hSpCas9 | positive selection | 3758921 | 80247298 | 80247321 | 18 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.1855665945734448 | [5] | [5,5] | 4 | hSpCas9 | positive selection | 3867526 | 80247291 | 80247314 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.16986140693095347 | [5] | [4,2] | -2 | hSpCas9 | positive selection | 3867527 | 80160457 | 80160480 | 18 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CATCGATGATGGATGATACGGGG | PARD6G | ENSG00000178184 | 0.15129169839582074 | [4] | [5,3] | 3 | hSpCas9 | positive selection | 3867528 | 80160431 | 80160454 | 18 | - | 26780180 | A375 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | 1.13752901038643 | [] | [] | 6 | hSpCas9 | negative selection | 3978430 | 80247291 | 80247314 | 18 | - | 26780180 | A375 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 1.362480409166 | [] | [] | 7 | hSpCas9 | negative selection | 3978431 | 80247298 | 80247321 | 18 | + | 26780180 | A375 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.94344136558008 | [] | [] | 4 | hSpCas9 | negative selection | 3978432 | 80159765 | 80159788 | 18 | + | 26780180 | A375 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 1.21499500945948 | [] | [] | 6 | hSpCas9 | negative selection | 3978433 | 80160431 | 80160454 | 18 | - | 26780180 | HT29 | viability (GeCKOv2 library) | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | 1.00202336356327 | [] | [] | 4 | hSpCas9 | negative selection | 4086396 | 80247291 | 80247314 | 18 | - | 26780180 | HT29 | viability (GeCKOv2 library) | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 1.81304722712127 | [] | [] | 8 | hSpCas9 | negative selection | 4086397 | 80247298 | 80247321 | 18 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 1.45659399998614 | [] | [] | 7 | hSpCas9 | negative selection | 4086398 | 80159765 | 80159788 | 18 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 1.58316136672867 | [] | [] | 8 | hSpCas9 | negative selection | 4086399 | 80160345 | 80160368 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | AGCGTGCGCGTGACCCCGCACGG | PARD6G | ENSG00000178184 | -0.07330750860979224 | [4] | [2,2] | -2 | hSpCas9 | positive selection | 4158846 | 80160454 | 80160477 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CGTATCATCCATCATCGATGTGG | PARD6G | ENSG00000178184 | -0.0018819681832773498 | [3] | [1,2] | 0 | hSpCas9 | positive selection | 4158848 | 80160345 | 80160368 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | AGCGTGCGCGTGACCCCGCACGG | PARD6G | ENSG00000178184 | 0.34376432298537785 | [4] | [2,3,2,1] | 2 | hSpCas9 | positive selection | 4222868 | 80160454 | 80160477 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CGTATCATCCATCATCGATGTGG | PARD6G | ENSG00000178184 | 0.5283604827735595 | [4] | [0,1,4,2] | 3 | hSpCas9 | positive selection | 4222870 | 80247298 | 80247321 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.053462011225122466 | [3] | [3,1] | 1 | hSpCas9 | positive selection | 4288839 | 80160431 | 80160454 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.40114410647428317 | [2] | [2,0] | -7 | hSpCas9 | positive selection | 4288840 | 80159765 | 80159788 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | -0.2470224839955394 | [2] | [2,0] | -5 | hSpCas9 | positive selection | 4288841 | 80247291 | 80247314 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.40768815392933366 | [2] | [3,0] | -7 | hSpCas9 | positive selection | 4353093 | 80160344 | 80160366 | 18 | - | 27760321 | OCIAML3 | viability | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -0.20142988899029085 | [615,661] | [432,442] | -2 | hSpCas9 | negative selection | 4425613 | 80160448 | 80160470 | 18 | - | 27760321 | OCIAML3 | viability | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.14103872955270957 | [458,417] | [459,270] | 1 | hSpCas9 | negative selection | 4425614 | 80160472 | 80160494 | 18 | + | 27760321 | OCIAML3 | viability | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | -0.3198243119126733 | [616,443] | [246,435] | -3 | hSpCas9 | negative selection | 4425615 | 80160528 | 80160550 | 18 | - | 27760321 | OCIAML3 | viability | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | -0.388666316424888 | [509,465] | [270,317] | -4 | hSpCas9 | negative selection | 4425616 | 80160344 | 80160366 | 18 | - | 27760321 | OCIAML2 | viability | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -0.2208703398631186 | [615,661] | [337,588] | -3 | hSpCas9 | negative selection | 4509076 | 80160448 | 80160470 | 18 | - | 27760321 | OCIAML2 | viability | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.1208861320953174 | [458,417] | [278,387] | -1 | hSpCas9 | negative selection | 4509077 | 80160472 | 80160494 | 18 | + | 27760321 | OCIAML2 | viability | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | 0.3380923819993058 | [616,443] | [410,702] | 4 | hSpCas9 | negative selection | 4509078 | 80160528 | 80160550 | 18 | - | 27760321 | OCIAML2 | viability | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | 0.3887428257020882 | [509,465] | [422,639] | 5 | hSpCas9 | negative selection | 4509079 | 80160344 | 80160366 | 18 | - | 27760321 | MV411 | viability | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -0.6788105470350683 | [615,661] | [91,524] | -5 | hSpCas9 | negative selection | 4592539 | 80160448 | 80160470 | 18 | - | 27760321 | MV411 | viability | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.4178024771751531 | [458,417] | [323,479] | 3 | hSpCas9 | negative selection | 4592540 | 80160472 | 80160494 | 18 | + | 27760321 | MV411 | viability | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | 0.9308401677227764 | [616,443] | [469,946] | 6 | hSpCas9 | negative selection | 4592541 | 80160528 | 80160550 | 18 | - | 27760321 | MV411 | viability | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | -0.5894266831767733 | [509,465] | [135,330] | -4 | hSpCas9 | negative selection | 4592542 | 80160344 | 80160366 | 18 | - | 27760321 | HL60 | viability | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -1.1293923671838342 | [615,661] | [209,271] | -8 | hSpCas9 | negative selection | 4676002 | 80160448 | 80160470 | 18 | - | 27760321 | HL60 | viability | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.19422550275050468 | [458,417] | [478,335] | 2 | hSpCas9 | negative selection | 4676003 | 80160472 | 80160494 | 18 | + | 27760321 | HL60 | viability | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | 0.3789341127220198 | [616,443] | [601,510] | 5 | hSpCas9 | negative selection | 4676004 | 80160528 | 80160550 | 18 | - | 27760321 | HL60 | viability | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | 0.6137537237863557 | [509,465] | [700,512] | 7 | hSpCas9 | negative selection | 4676005 | 80160344 | 80160366 | 18 | - | 27760321 | HT1080 | viability | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -0.1560863942289329 | [661,516] | [247,169] | 0 | hSpCas9 | negative selection | 4759465 | 80160448 | 80160470 | 18 | - | 27760321 | HT1080 | viability | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.5632052068128116 | [417,325] | [116,81] | -3 | hSpCas9 | negative selection | 4759466 | 80160472 | 80160494 | 18 | + | 27760321 | HT1080 | viability | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | -0.47335689307953777 | [443,346] | [144,78] | -2 | hSpCas9 | negative selection | 4759467 | 80160528 | 80160550 | 18 | - | 27760321 | HT1080 | viability | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | 0.09368683233348771 | [465,363] | [79,281] | 0 | hSpCas9 | negative selection | 4759468 | 80160344 | 80160366 | 18 | - | 27760321 | HT29 | viability after 7 days | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -0.17457440560545134 | [661,516] | [730,580,708] | -3 | hSpCas9 | negative selection | 4842928 | 80160448 | 80160470 | 18 | - | 27760321 | HT29 | viability after 7 days | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.4928709815430367 | [417,325] | [561,757,681] | 7 | hSpCas9 | negative selection | 4842929 | 80160472 | 80160494 | 18 | + | 27760321 | HT29 | viability after 7 days | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | 0.5066309170134002 | [443,346] | [689,913,562] | 7 | hSpCas9 | negative selection | 4842930 | 80160528 | 80160550 | 18 | - | 27760321 | HT29 | viability after 7 days | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | -0.1285484093706744 | [465,363] | [568,285,615] | -2 | hSpCas9 | negative selection | 4842931 | 80160344 | 80160366 | 18 | - | 27760321 | HT29 | viability after 25 days | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -0.2873405975933829 | [661,516] | [553,481,626] | -3 | hSpCas9 | negative selection | 4926391 | 80160448 | 80160470 | 18 | - | 27760321 | HT29 | viability after 25 days | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.45039948582366385 | [417,325] | [569,379,816] | 5 | hSpCas9 | negative selection | 4926392 | 80160472 | 80160494 | 18 | + | 27760321 | HT29 | viability after 25 days | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | 0.34042414585839886 | [443,346] | [580,566,566] | 3 | hSpCas9 | negative selection | 4926393 | 80160528 | 80160550 | 18 | - | 27760321 | HT29 | viability after 25 days | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | 0.02427185118395822 | [465,363] | [389,485,586] | 0 | hSpCas9 | negative selection | 4926394 | 80160344 | 80160366 | 18 | - | 27760321 | HT29 | viability after 22 days | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -0.5185789244699733 | [661,516] | [386,524,517] | -5 | hSpCas9 | negative selection | 5009854 | 80160448 | 80160470 | 18 | - | 27760321 | HT29 | viability after 22 days | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.2715403852352959 | [417,325] | [517,548,489] | 3 | hSpCas9 | negative selection | 5009855 | 80160472 | 80160494 | 18 | + | 27760321 | HT29 | viability after 22 days | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | -0.2310968345278802 | [443,346] | [332,472,363] | -2 | hSpCas9 | negative selection | 5009856 | 80160528 | 80160550 | 18 | - | 27760321 | HT29 | viability after 22 days | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | -0.14055665442195453 | [465,363] | [504,450,346] | -1 | hSpCas9 | negative selection | 5009857 | 80160344 | 80160366 | 18 | - | 27760321 | HT29 | viability after 19 days | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -0.2227885724784378 | [661,516] | [508,406,800] | -2 | hSpCas9 | negative selection | 5093317 | 80160448 | 80160470 | 18 | - | 27760321 | HT29 | viability after 19 days | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.8103916434968854 | [417,325] | [730,1130,387] | 8 | hSpCas9 | negative selection | 5093318 | 80160472 | 80160494 | 18 | + | 27760321 | HT29 | viability after 19 days | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | -0.13574950712234438 | [443,346] | [884,242,165] | -1 | hSpCas9 | negative selection | 5093319 | 80160528 | 80160550 | 18 | - | 27760321 | HT29 | viability after 19 days | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | -0.4426821232945666 | [465,363] | [398,232,417] | -4 | hSpCas9 | negative selection | 5093320 | 80160344 | 80160366 | 18 | - | 27760321 | HT29 | viability after 16 days | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -0.3560341055655239 | [661,516] | [538,404,606] | -4 | hSpCas9 | negative selection | 5176780 | 80160448 | 80160470 | 18 | - | 27760321 | HT29 | viability after 16 days | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.034527094301477136 | [417,325] | [499,336,450] | 0 | hSpCas9 | negative selection | 5176781 | 80160472 | 80160494 | 18 | + | 27760321 | HT29 | viability after 16 days | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | 0.5577482710450767 | [443,346] | [715,388,861] | 6 | hSpCas9 | negative selection | 5176782 | 80160528 | 80160550 | 18 | - | 27760321 | HT29 | viability after 16 days | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | -0.1420989934205681 | [465,363] | [369,399,487] | -1 | hSpCas9 | negative selection | 5176783 | 80160344 | 80160366 | 18 | - | 27760321 | HT29 | viability after 13 days | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -0.5539306577313918 | [661,516] | [396,523,475] | -6 | hSpCas9 | negative selection | 5260243 | 80160448 | 80160470 | 18 | - | 27760321 | HT29 | viability after 13 days | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.062348857228584124 | [417,325] | [367,568,416] | 0 | hSpCas9 | negative selection | 5260244 | 80160472 | 80160494 | 18 | + | 27760321 | HT29 | viability after 13 days | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | 0.1596942463748723 | [443,346] | [547,501,488] | 2 | hSpCas9 | negative selection | 5260245 | 80160528 | 80160550 | 18 | - | 27760321 | HT29 | viability after 13 days | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | -0.05977968135249112 | [465,363] | [494,315,567] | 0 | hSpCas9 | negative selection | 5260246 | 80160344 | 80160366 | 18 | - | 27760321 | HT29 | viability after 10 days | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | -0.5119089212589409 | [661,516] | [477,703,374] | -6 | hSpCas9 | negative selection | 5343706 | 80160448 | 80160470 | 18 | - | 27760321 | HT29 | viability after 10 days | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.7306423959878345 | [417,325] | [682,630,988] | 8 | hSpCas9 | negative selection | 5343707 | 80160472 | 80160494 | 18 | + | 27760321 | HT29 | viability after 10 days | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | 0.4301689617831219 | [443,346] | [691,410,880] | 6 | hSpCas9 | negative selection | 5343708 | 80160528 | 80160550 | 18 | - | 27760321 | HT29 | viability after 10 days | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | 0.11840191838897116 | [465,363] | [375,677,634] | 1 | hSpCas9 | negative selection | 5343709 | 80160344 | 80160366 | 18 | - | 27760321 | MOLM13 | viability | CGTGCGCGTGACCCCGCACGGG | PARD6G | ENSG00000178184 | 0.7262474146764942 | [615,661] | [530,658] | 5 | hSpCas9 | negative selection | 5427169 | 80160448 | 80160470 | 18 | - | 27760321 | MOLM13 | viability | TCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.10374133439316043 | [458,417] | [73,362] | 0 | hSpCas9 | negative selection | 5427170 | 80160472 | 80160494 | 18 | + | 27760321 | MOLM13 | viability | ATACGGGGCGGAAGTCGCGCGG | PARD6G | ENSG00000178184 | 1.6349585720610182 | [616,443] | [688,1116] | 9 | hSpCas9 | negative selection | 5427171 | 80160528 | 80160550 | 18 | - | 27760321 | MOLM13 | viability | TGGGCGCGCTGCGTGATGAAGG | PARD6G | ENSG00000178184 | -1.0666498559353121 | [509,465] | [152,112] | -6 | hSpCas9 | negative selection | 5427172 | 80247393 | 80247416 | 18 | + | 27661255 | K562 | viability | GGCCGCAGAAAGACTCCCGGGGG | PARD6G | ENSG00000178184 | 0.2177096551416518 | [749,830] | [726,737] | 7 | dCas9-KRAB | negative selection | 5500178 | 80247481 | 80247504 | 18 | + | 27661255 | K562 | viability | GCTGCGGGCCCGAGCTGGGCTGG | PARD6G | ENSG00000178184 | 0.22608491330868752 | [292,312] | [258,302] | 7 | dCas9-KRAB | negative selection | 5500179 | 80247506 | 80247529 | 18 | + | 27661255 | K562 | viability | GCGCGCCTCAGGGACTCCAGGGG | PARD6G | ENSG00000178184 | 0.5207026596690122 | [359,513] | [441,544] | 9 | dCas9-KRAB | negative selection | 5500180 | 80247118 | 80247141 | 18 | - | 27661255 | K562 | viability | GCTCCGCGGGACGCGCACTGGGG | PARD6G | ENSG00000178184 | 0.24089970797286697 | [192,351] | [314,202] | 7 | dCas9-KRAB | negative selection | 5500181 | 80247298 | 80247321 | 18 | + | 27260156 | BXPC3 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.12773269244641838 | [593] | [673,520,711,831] | 3 | hSpCas9 | negative selection | 5561299 | 80160431 | 80160454 | 18 | - | 27260156 | BXPC3 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.04209771242065258 | [340] | [397,212,300,489] | -1 | hSpCas9 | negative selection | 5561300 | 80159765 | 80159788 | 18 | + | 27260156 | BXPC3 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.2884939283614158 | [399] | [428,601,516,492] | 6 | hSpCas9 | negative selection | 5561301 | 80247291 | 80247314 | 18 | - | 27260156 | BXPC3 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 0.16613340300136645 | [415] | [469,512,419,552] | 3 | hSpCas9 | negative selection | 5625553 | 80247298 | 80247321 | 18 | + | 27260156 | A673 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.1959411473044991 | [593] | [713,573,553,661] | -5 | hSpCas9 | negative selection | 5682550 | 80160431 | 80160454 | 18 | - | 27260156 | A673 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.1271406918148919 | [340] | [395,374,318,413] | -3 | hSpCas9 | negative selection | 5682551 | 80159765 | 80159788 | 18 | + | 27260156 | A673 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.1634434175918339 | [399] | [578,525,524,524] | 4 | hSpCas9 | negative selection | 5682552 | 80247291 | 80247314 | 18 | - | 27260156 | A673 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.004513263008545959 | [415] | [530,461,525,474] | 0 | hSpCas9 | negative selection | 5746804 | 80247298 | 80247321 | 18 | + | 27260156 | A375 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.07511917065898277 | [593] | [671,696,773,511] | -1 | hSpCas9 | negative selection | 5803801 | 80160431 | 80160454 | 18 | - | 27260156 | A375 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | 0.1660663425033852 | [340] | [317,592,362,521] | 2 | hSpCas9 | negative selection | 5803802 | 80159765 | 80159788 | 18 | + | 27260156 | A375 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.018918198890781085 | [399] | [486,674,369,396] | 0 | hSpCas9 | negative selection | 5803803 | 80247291 | 80247314 | 18 | - | 27260156 | A375 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.0922636422842672 | [415] | [399,735,305,421] | -1 | hSpCas9 | negative selection | 5868055 | 80247298 | 80247321 | 18 | + | 27260156 | COLO741 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.028536715765305642 | [593] | [861,762,707] | 0 | hSpCas9 | negative selection | 5925052 | 80160431 | 80160454 | 18 | - | 27260156 | COLO741 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | 0.10425981151427538 | [340] | [573,387,451] | 2 | hSpCas9 | negative selection | 5925053 | 80159765 | 80159788 | 18 | + | 27260156 | COLO741 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.22595395469625842 | [399] | [606,592,592] | 5 | hSpCas9 | negative selection | 5925054 | 80247291 | 80247314 | 18 | - | 27260156 | COLO741 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 0.14054227013706927 | [415] | [700,465,597] | 3 | hSpCas9 | negative selection | 5989306 | 80247298 | 80247321 | 18 | + | 27260156 | CAL120 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.2534374837306636 | [593] | [576,627,647] | -4 | hSpCas9 | negative selection | 6046303 | 80160431 | 80160454 | 18 | - | 27260156 | CAL120 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.08061340565604264 | [340] | [246,562,370] | -1 | hSpCas9 | negative selection | 6046304 | 80159765 | 80159788 | 18 | + | 27260156 | CAL120 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | -0.20322262776542568 | [399] | [660,277,392] | -3 | hSpCas9 | negative selection | 6046305 | 80247291 | 80247314 | 18 | - | 27260156 | CAL120 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.7732427880285007 | [415] | [309,262,335] | -8 | hSpCas9 | negative selection | 6110557 | 80247298 | 80247321 | 18 | + | 27260156 | CADOES1 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.2860098670443184 | [593] | [356,551,421,482] | -5 | hSpCas9 | negative selection | 6167554 | 80160431 | 80160454 | 18 | - | 27260156 | CADOES1 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.004287448872521138 | [340] | [266,367,391,234] | 0 | hSpCas9 | negative selection | 6167555 | 80159765 | 80159788 | 18 | + | 27260156 | CADOES1 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | -0.02711388377778326 | [399] | [406,345,271,437] | 0 | hSpCas9 | negative selection | 6167556 | 80247291 | 80247314 | 18 | - | 27260156 | CADOES1 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.5984574363881638 | [415] | [189,392,224,212] | -8 | hSpCas9 | negative selection | 6231808 | 80247298 | 80247321 | 18 | + | 27260156 | EWS502 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.13571997595328017 | [593] | [645,626,853,641] | 2 | hSpCas9 | negative selection | 6288805 | 80160431 | 80160454 | 18 | - | 27260156 | EWS502 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.11207848113212343 | [340] | [332,328,208,472] | -2 | hSpCas9 | negative selection | 6288806 | 80159765 | 80159788 | 18 | + | 27260156 | EWS502 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.3323761348984734 | [399] | [348,552,653,603] | 6 | hSpCas9 | negative selection | 6288807 | 80247291 | 80247314 | 18 | - | 27260156 | EWS502 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.2180047390289711 | [415] | [229,401,536,362] | -4 | hSpCas9 | negative selection | 6353059 | 80247298 | 80247321 | 18 | + | 27260156 | EW8 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.007203829316149879 | [593] | [670,448,334,504] | 0 | hSpCas9 | negative selection | 6410056 | 80160431 | 80160454 | 18 | - | 27260156 | EW8 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.1695813838768226 | [340] | [306,227,232,222] | -3 | hSpCas9 | negative selection | 6410057 | 80159765 | 80159788 | 18 | + | 27260156 | EW8 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.1779361806756225 | [399] | [250,471,261,485] | 3 | hSpCas9 | negative selection | 6410058 | 80247291 | 80247314 | 18 | - | 27260156 | EW8 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 0.16860396478845563 | [415] | [587,396,242,332] | 3 | hSpCas9 | negative selection | 6474310 | 80247298 | 80247321 | 18 | + | 27260156 | CORL105 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.14832118216105888 | [593] | [656,540,645,670] | -3 | hSpCas9 | negative selection | 6531307 | 80160431 | 80160454 | 18 | - | 27260156 | CORL105 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.16166345010074795 | [340] | [396,354,306,361] | -3 | hSpCas9 | negative selection | 6531308 | 80159765 | 80159788 | 18 | + | 27260156 | CORL105 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.10745421345776857 | [399] | [483,470,513,549] | 2 | hSpCas9 | negative selection | 6531309 | 80247291 | 80247314 | 18 | - | 27260156 | CORL105 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.6183136342103992 | [415] | [268,269,399,341] | -8 | hSpCas9 | negative selection | 6595561 | 80247298 | 80247321 | 18 | + | 27260156 | HS294T | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.11106502767432513 | [593] | [129,217,300,207] | -1 | hSpCas9 | negative selection | 6652558 | 80160431 | 80160454 | 18 | - | 27260156 | HS294T | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.34174415248375295 | [340] | [91,54,125,153] | -5 | hSpCas9 | negative selection | 6652559 | 80159765 | 80159788 | 18 | + | 27260156 | HS294T | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | -0.10946230983186986 | [399] | [88,153,135,209] | -1 | hSpCas9 | negative selection | 6652560 | 80247291 | 80247314 | 18 | - | 27260156 | HS294T | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 0.12251382385634867 | [415] | [82,139,111,414] | 1 | hSpCas9 | negative selection | 6716812 | 80247298 | 80247321 | 18 | + | 27260156 | HCC44 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.16762483606716977 | [593] | [542,881,953,633] | 2 | hSpCas9 | negative selection | 6773809 | 80160431 | 80160454 | 18 | - | 27260156 | HCC44 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | 0.4864136632060877 | [340] | [459,538,643,524] | 7 | hSpCas9 | negative selection | 6773810 | 80159765 | 80159788 | 18 | + | 27260156 | HCC44 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.29774221547814467 | [399] | [462,691,694,371] | 5 | hSpCas9 | negative selection | 6773811 | 80247291 | 80247314 | 18 | - | 27260156 | HCC44 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 0.08060097493068166 | [415] | [526,494,567,413] | 1 | hSpCas9 | negative selection | 6838063 | 80247298 | 80247321 | 18 | + | 27260156 | G402 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.7410805560834248 | [593] | [297,599,370,452] | -7 | hSpCas9 | negative selection | 6895060 | 80160431 | 80160454 | 18 | - | 27260156 | G402 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -1.1414269215815258 | [340] | [165,171,190,218] | -8 | hSpCas9 | negative selection | 6895061 | 80159765 | 80159788 | 18 | + | 27260156 | G402 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | -0.056478100614221344 | [399] | [634,295,289,658] | 0 | hSpCas9 | negative selection | 6895062 | 80247291 | 80247314 | 18 | - | 27260156 | G402 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -1.0629063023348848 | [415] | [349,225,199,210] | -8 | hSpCas9 | negative selection | 6959314 | 80247298 | 80247321 | 18 | + | 27260156 | L33 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.09437155932098945 | [593] | [508,216,422,515] | -2 | hSpCas9 | negative selection | 7016311 | 80160431 | 80160454 | 18 | - | 27260156 | L33 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -1.0011019781530142 | [340] | [122,77,139,146] | -9 | hSpCas9 | negative selection | 7016312 | 80159765 | 80159788 | 18 | + | 27260156 | L33 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.13909255897457148 | [399] | [430,215,232,432] | 3 | hSpCas9 | negative selection | 7016313 | 80247291 | 80247314 | 18 | - | 27260156 | L33 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.2250078013695298 | [415] | [282,154,264,342] | -5 | hSpCas9 | negative selection | 7080565 | 80247298 | 80247321 | 18 | + | 27260156 | K562 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.04288566461098725 | [593] | [576,483,376,599] | 0 | hSpCas9 | negative selection | 7137562 | 80160431 | 80160454 | 18 | - | 27260156 | K562 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | 0.1636152173635721 | [340] | [75,147,572,505] | 2 | hSpCas9 | negative selection | 7137563 | 80159765 | 80159788 | 18 | + | 27260156 | K562 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.5491665682596208 | [399] | [532,520,704,338] | 7 | hSpCas9 | negative selection | 7137564 | 80247291 | 80247314 | 18 | - | 27260156 | K562 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | 0.08385017301795905 | [415] | [829,417,218,160] | 1 | hSpCas9 | negative selection | 7201816 | 80247298 | 80247321 | 18 | + | 27260156 | HT29 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.07109739681439625 | [593] | [698,635,907,518] | -1 | hSpCas9 | negative selection | 7258813 | 80160431 | 80160454 | 18 | - | 27260156 | HT29 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.1850119006963486 | [340] | [377,506,379,221] | -4 | hSpCas9 | negative selection | 7258814 | 80159765 | 80159788 | 18 | + | 27260156 | HT29 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.16133822737982917 | [399] | [506,471,619,560] | 3 | hSpCas9 | negative selection | 7258815 | 80247291 | 80247314 | 18 | - | 27260156 | HT29 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.5945873566286222 | [415] | [393,336,420,205] | -7 | hSpCas9 | negative selection | 7323067 | 80247298 | 80247321 | 18 | + | 27260156 | MHHES1 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.15561506094390204 | [593] | [1095,703,698,548] | 3 | hSpCas9 | negative selection | 7380064 | 80160431 | 80160454 | 18 | - | 27260156 | MHHES1 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.05630759547097813 | [340] | [251,346,635,247] | -1 | hSpCas9 | negative selection | 7380065 | 80159765 | 80159788 | 18 | + | 27260156 | MHHES1 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.03063754899938037 | [399] | [468,515,475,391] | 0 | hSpCas9 | negative selection | 7380066 | 80247291 | 80247314 | 18 | - | 27260156 | MHHES1 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.3336549472915939 | [415] | [434,420,543,145] | -6 | hSpCas9 | negative selection | 7444318 | 80247298 | 80247321 | 18 | + | 27260156 | MEWO | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.15854661503831233 | [593] | [637,435,446] | -3 | hSpCas9 | negative selection | 7501315 | 80160431 | 80160454 | 18 | - | 27260156 | MEWO | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.22252263460347127 | [340] | [210,298,297] | -5 | hSpCas9 | negative selection | 7501316 | 80159765 | 80159788 | 18 | + | 27260156 | MEWO | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | -0.07784959018191814 | [399] | [276,270,500] | -2 | hSpCas9 | negative selection | 7501317 | 80247291 | 80247314 | 18 | - | 27260156 | MEWO | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.5400098826094673 | [415] | [373,177,271] | -8 | hSpCas9 | negative selection | 7565569 | 80247298 | 80247321 | 18 | + | 27260156 | LNCAPCLONEFGC | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.5179401348079232 | [593] | [458,262,451,345] | -7 | hSpCas9 | negative selection | 7622566 | 80160431 | 80160454 | 18 | - | 27260156 | LNCAPCLONEFGC | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.4379390019145543 | [340] | [214,158,323,232] | -6 | hSpCas9 | negative selection | 7622567 | 80159765 | 80159788 | 18 | + | 27260156 | LNCAPCLONEFGC | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | -0.31870382315204715 | [399] | [268,258,361,284] | -5 | hSpCas9 | negative selection | 7622568 | 80247291 | 80247314 | 18 | - | 27260156 | LNCAPCLONEFGC | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.8237951052753656 | [415] | [191,206,271,189] | -8 | hSpCas9 | negative selection | 7686820 | 80247298 | 80247321 | 18 | + | 27260156 | PANC0327 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.21917464437345788 | [593] | [629,201,514,512] | -3 | hSpCas9 | negative selection | 7743817 | 80160431 | 80160454 | 18 | - | 27260156 | PANC0327 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.12244255845585911 | [340] | [190,191,345,387] | -2 | hSpCas9 | negative selection | 7743818 | 80159765 | 80159788 | 18 | + | 27260156 | PANC0327 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.7314674371934063 | [399] | [697,633,629,400] | 9 | hSpCas9 | negative selection | 7743819 | 80247291 | 80247314 | 18 | - | 27260156 | PANC0327 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.3056485575645542 | [415] | [373,207,417,213] | -4 | hSpCas9 | negative selection | 7808071 | 80247298 | 80247321 | 18 | + | 27260156 | NCIH2009 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.2098707582534069 | [593] | [1161,954,800] | 3 | hSpCas9 | negative selection | 7865068 | 80160431 | 80160454 | 18 | - | 27260156 | NCIH2009 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.5921693309005243 | [340] | [581,268,149] | -6 | hSpCas9 | negative selection | 7865069 | 80159765 | 80159788 | 18 | + | 27260156 | NCIH2009 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.020605516242690997 | [399] | [805,511,429] | 0 | hSpCas9 | negative selection | 7865070 | 80247291 | 80247314 | 18 | - | 27260156 | NCIH2009 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.16329919023115713 | [415] | [595,484,490] | -2 | hSpCas9 | negative selection | 7929322 | 80247298 | 80247321 | 18 | + | 27260156 | NCIH1373 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.10099259565528296 | [593] | [678,766,851,138] | 1 | hSpCas9 | negative selection | 7986319 | 80160431 | 80160454 | 18 | - | 27260156 | NCIH1373 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.500532843472244 | [340] | [250,202,339,75] | -5 | hSpCas9 | negative selection | 7986320 | 80159765 | 80159788 | 18 | + | 27260156 | NCIH1373 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.17520971889713338 | [399] | [810,309,583,98] | 1 | hSpCas9 | negative selection | 7986321 | 80247291 | 80247314 | 18 | - | 27260156 | NCIH1373 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.03174544152826686 | [415] | [402,487,738,40] | 0 | hSpCas9 | negative selection | 8050573 | 80247298 | 80247321 | 18 | + | 27260156 | PATU8902 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.26253977093078334 | [593] | [844,942,695,1632] | 2 | hSpCas9 | negative selection | 8107570 | 80160431 | 80160454 | 18 | - | 27260156 | PATU8902 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.12666666695127987 | [340] | [635,578,273,266] | -1 | hSpCas9 | negative selection | 8107571 | 80159765 | 80159788 | 18 | + | 27260156 | PATU8902 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.1679290684757806 | [399] | [236,487,399,1546] | 1 | hSpCas9 | negative selection | 8107572 | 80247291 | 80247314 | 18 | - | 27260156 | PATU8902 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.21402870202768598 | [415] | [444,360,598,571] | -2 | hSpCas9 | negative selection | 8171824 | 80247298 | 80247321 | 18 | + | 27260156 | PANC1 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.8847065730903578 | [593] | [244,377,276,229] | -8 | hSpCas9 | negative selection | 8228821 | 80160431 | 80160454 | 18 | - | 27260156 | PANC1 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.6154963726755927 | [340] | [185,303,115,179] | -7 | hSpCas9 | negative selection | 8228822 | 80159765 | 80159788 | 18 | + | 27260156 | PANC1 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | -0.3553045146359566 | [399] | [333,389,225,160] | -5 | hSpCas9 | negative selection | 8228823 | 80247291 | 80247314 | 18 | - | 27260156 | PANC1 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.6469796005955275 | [415] | [170,237,284,219] | -7 | hSpCas9 | negative selection | 8293075 | 80247298 | 80247321 | 18 | + | 27260156 | PANC0813 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.17702871968555828 | [593] | [842,971,763,590] | 3 | hSpCas9 | negative selection | 8350072 | 80160431 | 80160454 | 18 | - | 27260156 | PANC0813 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.5230399030516777 | [340] | [372,147,245,351] | -7 | hSpCas9 | negative selection | 8350073 | 80159765 | 80159788 | 18 | + | 27260156 | PANC0813 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.15302856724841932 | [399] | [682,418,640,369] | 2 | hSpCas9 | negative selection | 8350074 | 80247291 | 80247314 | 18 | - | 27260156 | PANC0813 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.26237327142129224 | [415] | [509,292,469,367] | -4 | hSpCas9 | negative selection | 8414326 | 80247298 | 80247321 | 18 | + | 27260156 | RDES | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.07475836017579696 | [593] | [630,601,635,1066] | 1 | hSpCas9 | negative selection | 8471323 | 80160431 | 80160454 | 18 | - | 27260156 | RDES | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.2501556356325469 | [340] | [271,312,300,454] | -4 | hSpCas9 | negative selection | 8471324 | 80159765 | 80159788 | 18 | + | 27260156 | RDES | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | -0.056218468659093995 | [399] | [338,413,536,504] | -1 | hSpCas9 | negative selection | 8471325 | 80247291 | 80247314 | 18 | - | 27260156 | RDES | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.02690078580562691 | [415] | [465,414,447,550] | 0 | hSpCas9 | negative selection | 8535577 | 80247298 | 80247321 | 18 | + | 27260156 | PC3 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.23262527131921773 | [593] | [331,413,632,725] | -5 | hSpCas9 | negative selection | 8592574 | 80160431 | 80160454 | 18 | - | 27260156 | PC3 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.20382286609208827 | [340] | [186,267,530,306] | -4 | hSpCas9 | negative selection | 8592575 | 80159765 | 80159788 | 18 | + | 27260156 | PC3 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.15015837359452694 | [399] | [202,571,772,412] | 3 | hSpCas9 | negative selection | 8592576 | 80247291 | 80247314 | 18 | - | 27260156 | PC3 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.6281451497859198 | [415] | [203,216,533,219] | -8 | hSpCas9 | negative selection | 8656828 | 80247298 | 80247321 | 18 | + | 27260156 | PATU8988T | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.12513663578515233 | [593] | [449,542,437,689] | -2 | hSpCas9 | negative selection | 8713825 | 80160431 | 80160454 | 18 | - | 27260156 | PATU8988T | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | 0.019735164104341063 | [340] | [358,416,315,244] | 0 | hSpCas9 | negative selection | 8713826 | 80159765 | 80159788 | 18 | + | 27260156 | PATU8988T | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.4256063376920858 | [399] | [361,612,377,752] | 7 | hSpCas9 | negative selection | 8713827 | 80247291 | 80247314 | 18 | - | 27260156 | PATU8988T | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.11020366724823227 | [415] | [415,232,506,313] | -2 | hSpCas9 | negative selection | 8778079 | 80247298 | 80247321 | 18 | + | 27260156 | T47D | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.014336888911535173 | [593] | [738,596,714,754] | 0 | hSpCas9 | negative selection | 8835076 | 80160431 | 80160454 | 18 | - | 27260156 | T47D | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.3510234358859286 | [340] | [335,225,342,348] | -6 | hSpCas9 | negative selection | 8835077 | 80159765 | 80159788 | 18 | + | 27260156 | T47D | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.24619667388749655 | [399] | [647,458,540,571] | 5 | hSpCas9 | negative selection | 8835078 | 80247291 | 80247314 | 18 | - | 27260156 | T47D | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.3073622662105617 | [415] | [379,328,461,399] | -6 | hSpCas9 | negative selection | 8899330 | 80247298 | 80247321 | 18 | + | 27260156 | SU8686 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.36928748893886315 | [593] | [697,633,841,913] | 6 | hSpCas9 | negative selection | 8956327 | 80160431 | 80160454 | 18 | - | 27260156 | SU8686 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.07333677095226471 | [340] | [244,304,391,359] | -1 | hSpCas9 | negative selection | 8956328 | 80159765 | 80159788 | 18 | + | 27260156 | SU8686 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.3629563444157611 | [399] | [501,451,549,547] | 6 | hSpCas9 | negative selection | 8956329 | 80247291 | 80247314 | 18 | - | 27260156 | SU8686 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.1818212644366048 | [415] | [249,423,391,396] | -3 | hSpCas9 | negative selection | 9020581 | 80247298 | 80247321 | 18 | + | 27260156 | SKES1 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.06942593075818188 | [593] | [584,561,527,578] | -1 | hSpCas9 | negative selection | 9077578 | 80160431 | 80160454 | 18 | - | 27260156 | SKES1 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.18110112577146925 | [340] | [390,322,275,230] | -4 | hSpCas9 | negative selection | 9077579 | 80159765 | 80159788 | 18 | + | 27260156 | SKES1 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.04096531459779815 | [399] | [411,415,486,331] | 0 | hSpCas9 | negative selection | 9077580 | 80247291 | 80247314 | 18 | - | 27260156 | SKES1 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.38044307099739544 | [415] | [238,331,334,351] | -7 | hSpCas9 | negative selection | 9141832 | 80247298 | 80247321 | 18 | + | 27260156 | TOV112D | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.18411696478039224 | [593] | [522,1049,761,452] | 3 | hSpCas9 | negative selection | 9198829 | 80160431 | 80160454 | 18 | - | 27260156 | TOV112D | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.2511495788478216 | [340] | [412,272,197,270] | -5 | hSpCas9 | negative selection | 9198830 | 80159765 | 80159788 | 18 | + | 27260156 | TOV112D | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | -0.018866733517775652 | [399] | [356,483,414,344] | 0 | hSpCas9 | negative selection | 9198831 | 80247291 | 80247314 | 18 | - | 27260156 | TOV112D | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.12268620955984205 | [415] | [401,563,396,217] | -2 | hSpCas9 | negative selection | 9263083 | 80247298 | 80247321 | 18 | + | 27260156 | TC71 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.0016339611246936614 | [593] | [562,721,594,668] | 0 | hSpCas9 | negative selection | 9320080 | 80160431 | 80160454 | 18 | - | 27260156 | TC71 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.15305564258895282 | [340] | [354,243,339,377] | -4 | hSpCas9 | negative selection | 9320081 | 80159765 | 80159788 | 18 | + | 27260156 | TC71 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | 0.017565383742852242 | [399] | [298,508,485,443] | 0 | hSpCas9 | negative selection | 9320082 | 80247291 | 80247314 | 18 | - | 27260156 | TC71 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.36247444789429245 | [415] | [314,341,411,314] | -7 | hSpCas9 | negative selection | 9384334 | 80247298 | 80247321 | 18 | + | 27260156 | TC32 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.3245675214171802 | [593] | [339,433,596,426] | -5 | hSpCas9 | negative selection | 9441331 | 80160431 | 80160454 | 18 | - | 27260156 | TC32 | viability | ACCTGGTCCCCGAGACGCACCGG | PARD6G | ENSG00000178184 | -0.3386522087181269 | [340] | [224,155,436,253] | -6 | hSpCas9 | negative selection | 9441332 | 80159765 | 80159788 | 18 | + | 27260156 | TC32 | viability | GGGAGTCTAGAGCGTGACCGCGG | PARD6G | ENSG00000178184 | -0.26105992583347837 | [399] | [305,201,453,343] | -5 | hSpCas9 | negative selection | 9441333 | 80247291 | 80247314 | 18 | - | 27260156 | TC32 | viability | ATTCTACGATTGCAGCGCAGTGG | PARD6G | ENSG00000178184 | -0.44306690698588996 | [415] | [337,97,441,352] | -7 | hSpCas9 | negative selection | 9505585 | 80160190 | 80160213 | 18 | + | 27869803 | HPAFII | viability after 27 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -0.5381609933052816 | [400] | [82,196,NaN] | -4 | hSpCas9 | negative selection | 9565193 | 80160448 | 80160471 | 18 | - | 27869803 | HPAFII | viability after 27 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.34506735159586555 | [106] | [95,50,NaN] | 2 | hSpCas9 | negative selection | 9565194 | 80183119 | 80183142 | 18 | + | 27869803 | HPAFII | viability after 27 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 1.8743384330987238 | [68] | [228,52,NaN] | 9 | hSpCas9 | negative selection | 9565195 | 80247276 | 80247299 | 18 | - | 27869803 | HPAFII | viability after 27 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -0.8498883435613801 | [809] | [196,268,NaN] | -5 | hSpCas9 | negative selection | 9565196 | 80247298 | 80247321 | 18 | + | 27869803 | HPAFII | viability after 27 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -1.9691186109239034 | [108] | [6,20,NaN] | -8 | hSpCas9 | negative selection | 9565197 | 80160190 | 80160213 | 18 | + | 27869803 | HPAFII | viability after 15 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -0.6632391105664064 | [400] | [318,242,NaN] | -6 | hSpCas9 | negative selection | 9647642 | 80160448 | 80160471 | 18 | - | 27869803 | HPAFII | viability after 15 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.09655506669996927 | [106] | [183,84,NaN] | 1 | hSpCas9 | negative selection | 9647643 | 80183119 | 80183142 | 18 | + | 27869803 | HPAFII | viability after 15 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 1.0030213965933164 | [68] | [221,102,NaN] | 9 | hSpCas9 | negative selection | 9647644 | 80247276 | 80247299 | 18 | - | 27869803 | HPAFII | viability after 15 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -0.2835572959234425 | [809] | [848,631,NaN] | -3 | hSpCas9 | negative selection | 9647645 | 80247298 | 80247321 | 18 | + | 27869803 | HPAFII | viability after 15 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.6293379855205978 | [108] | [55,87,NaN] | -6 | hSpCas9 | negative selection | 9647646 | 80160190 | 80160213 | 18 | + | 27869803 | ASPC1 | viability after 36 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -0.4596901086677243 | [960] | [376,219,166] | -5 | hSpCas9 | negative selection | 9730091 | 80160448 | 80160471 | 18 | - | 27869803 | ASPC1 | viability after 36 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -1.120389113771206 | [372] | [82,98,11] | -8 | hSpCas9 | negative selection | 9730092 | 80183119 | 80183142 | 18 | + | 27869803 | ASPC1 | viability after 36 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | -1.0881305363282956 | [317] | [42,35,70] | -8 | hSpCas9 | negative selection | 9730093 | 80247276 | 80247299 | 18 | - | 27869803 | ASPC1 | viability after 36 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -0.34367906377662183 | [1741] | [599,519,356] | -4 | hSpCas9 | negative selection | 9730094 | 80247298 | 80247321 | 18 | + | 27869803 | ASPC1 | viability after 36 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.715049038217439 | [321] | [378,161,63] | 7 | hSpCas9 | negative selection | 9730095 | 80160190 | 80160213 | 18 | + | 27869803 | PATU8988S | viability after 35 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -0.08009759284579254 | [927] | [382,323,NaN] | -1 | hSpCas9 | negative selection | 9812540 | 80160448 | 80160471 | 18 | - | 27869803 | PATU8988S | viability after 35 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.27480919000954973 | [408] | [203,67,NaN] | -3 | hSpCas9 | negative selection | 9812541 | 80183119 | 80183142 | 18 | + | 27869803 | PATU8988S | viability after 35 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 0.5125840121786387 | [294] | [167,170,NaN] | 6 | hSpCas9 | negative selection | 9812542 | 80247276 | 80247299 | 18 | - | 27869803 | PATU8988S | viability after 35 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.6258584933874818 | [1473] | [952,878,NaN] | 7 | hSpCas9 | negative selection | 9812543 | 80247298 | 80247321 | 18 | + | 27869803 | PATU8988S | viability after 35 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.6130825601418486 | [173] | [188,24,NaN] | 6 | hSpCas9 | negative selection | 9812544 | 80160190 | 80160213 | 18 | + | 27869803 | PATU8988S | viability after 31 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | 0.13146735081636596 | [927] | [297,541,NaN] | 1 | hSpCas9 | negative selection | 9894989 | 80160448 | 80160471 | 18 | - | 27869803 | PATU8988S | viability after 31 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | 0.1615725125408624 | [408] | [243,103,NaN] | 2 | hSpCas9 | negative selection | 9894990 | 80183119 | 80183142 | 18 | + | 27869803 | PATU8988S | viability after 31 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 0.6807939440191779 | [294] | [199,173,NaN] | 7 | hSpCas9 | negative selection | 9894991 | 80247276 | 80247299 | 18 | - | 27869803 | PATU8988S | viability after 31 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | 0.4565480892611209 | [1473] | [707,931,NaN] | 5 | hSpCas9 | negative selection | 9894992 | 80247298 | 80247321 | 18 | + | 27869803 | PATU8988S | viability after 31 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.8447469652156397 | [173] | [150,90,NaN] | 8 | hSpCas9 | negative selection | 9894993 | 80160190 | 80160213 | 18 | + | 27869803 | HPAFII | viability after 35 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -1.0243105454327952 | [400] | [64,138,NaN] | -5 | hSpCas9 | negative selection | 9977438 | 80160448 | 80160471 | 18 | - | 27869803 | HPAFII | viability after 35 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.05259237872150746 | [106] | [39,65,NaN] | 0 | hSpCas9 | negative selection | 9977439 | 80183119 | 80183142 | 18 | + | 27869803 | HPAFII | viability after 35 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 2.1824606618627556 | [68] | [222,85,NaN] | 9 | hSpCas9 | negative selection | 9977440 | 80247276 | 80247299 | 18 | - | 27869803 | HPAFII | viability after 35 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -1.0398591247541265 | [809] | [142,262,NaN] | -5 | hSpCas9 | negative selection | 9977441 | 80247298 | 80247321 | 18 | + | 27869803 | HPAFII | viability after 35 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -3.6842809586701994 | [108] | [0,7,NaN] | -9 | hSpCas9 | negative selection | 9977442 | 80160190 | 80160213 | 18 | + | 27869803 | HPAFII | viability after 31 days | CGATCATCATGTCCGTGACCTGG | PARD6G | ENSG00000178184 | -1.209825239967552 | [400] | [47,150,NaN] | -6 | hSpCas9 | negative selection | 10059887 | 80160448 | 80160471 | 18 | - | 27869803 | HPAFII | viability after 31 days | ATCCATCATCGATGTGGACCTGG | PARD6G | ENSG00000178184 | -0.3834141604218426 | [106] | [57,32,NaN] | -3 | hSpCas9 | negative selection | 10059888 | 80183119 | 80183142 | 18 | + | 27869803 | HPAFII | viability after 31 days | GAGTCAGGTTCCTGGTCGCAGGG | PARD6G | ENSG00000178184 | 2.42612844797164 | [68] | [288,119,NaN] | 9 | hSpCas9 | negative selection | 10059889 | 80247276 | 80247299 | 18 | - | 27869803 | HPAFII | viability after 31 days | CGCAGTGGAAGTCAAGAGCAAGG | PARD6G | ENSG00000178184 | -1.2140651353818819 | [809] | [138,257,NaN] | -6 | hSpCas9 | negative selection | 10059890 | 80247298 | 80247321 | 18 | + | 27869803 | HPAFII | viability after 31 days | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -2.5220315997631926 | [108] | [13,6,NaN] | -8 | hSpCas9 | negative selection | 10059891 | 80247298 | 80247321 | 18 | + | 28162770 | P31FUJ | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.5427038516038858 | [228] | [391] | 6 | hSpCas9 | negative selection | 10206875 | 80247298 | 80247321 | 18 | + | 28162770 | TF1 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | NaN | [NaN] | [290] | 1 | hSpCas9 | negative selection | 10376241 | 80247298 | 80247321 | 18 | + | 28162770 | SKM1 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.02367015558670066 | [68] | [123] | 0 | hSpCas9 | negative selection | 10545607 | 80247298 | 80247321 | 18 | + | 28162770 | SKM1 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.02367015558670066 | [68] | [123] | 0 | hSpCas9 | negative selection | 10714973 | 80247298 | 80247321 | 18 | + | 28162770 | PL21 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.3076550257093761 | [272] | [95] | -2 | hSpCas9 | negative selection | 10884339 | 80247298 | 80247321 | 18 | + | 28162770 | P31FUJ | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.5427038516038858 | [228] | [391] | 6 | hSpCas9 | negative selection | 11053705 | 80247298 | 80247321 | 18 | + | 28162770 | OCIAML5 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.7595544320744587 | [150] | [160] | -5 | hSpCas9 | negative selection | 11223071 | 80247298 | 80247321 | 18 | + | 28162770 | EOL1 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.6106124674367029 | [449] | [361] | 5 | hSpCas9 | negative selection | 11392437 | 80247298 | 80247321 | 18 | + | 28162770 | MOLM13 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.6666692456590766 | [351] | [403] | 5 | hSpCas9 | negative selection | 11561803 | 80247298 | 80247321 | 18 | + | 28162770 | HEL | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.5284554045044656 | [301] | [278] | 4 | hSpCas9 | negative selection | 11731169 | 80247298 | 80247321 | 18 | + | 28162770 | MV411 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.23336236557105244 | [205] | [203] | 2 | hSpCas9 | negative selection | 11900535 | 80247298 | 80247321 | 18 | + | 28162770 | MONOMAC1 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.4743404054790756 | [161] | [257] | 5 | hSpCas9 | negative selection | 12069901 | 80247298 | 80247321 | 18 | + | 28162770 | OCIAML2 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | 0.17071514537651372 | [45] | [286] | 1 | hSpCas9 | negative selection | 12239267 | 80247298 | 80247321 | 18 | + | 28162770 | OCIAML3 | viability | GCTGCAATCGTAGAATCGCAAGG | PARD6G | ENSG00000178184 | -0.08038392132326933 | [75] | [216] | 0 | hSpCas9 | negative selection | 12408633 |