Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:55872
• Symbol:PBK
• Description:PDZ binding kinase

DataSource: http://genomecrispr.dkfz.de/#!/results/PBK

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
27811072	27811095	8	-	26472758	Jiyoye	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	0.2634399040444241	[231]	[209]	2	hSpCas9	negative selection	116461
27822428	27822451	8	-	26472758	Jiyoye	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	4.2145303035634765	[0]	[13]	9	hSpCas9	negative selection	116462
27833105	27833128	8	-	26472758	Jiyoye	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.6612656745960028	[517]	[246]	-5	hSpCas9	negative selection	116463
27811094	27811117	8	-	26472758	Jiyoye	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.07505151951262268	[354]	[281]	0	hSpCas9	negative selection	116464
27828143	27828166	8	+	26472758	Jiyoye	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-1.1529124505762536	[229]	[77]	-7	hSpCas9	negative selection	116465
27820564	27820587	8	+	26472758	Jiyoye	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.6426634604540046	[140]	[165]	5	hSpCas9	negative selection	116466
27828127	27828150	8	-	26472758	Jiyoye	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.451765532529944	[222]	[229]	3	hSpCas9	negative selection	116467
27822458	27822481	8	-	26472758	Jiyoye	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	-0.1318508350484237	[169]	[116]	-1	hSpCas9	negative selection	116468
27828162	27828185	8	+	26472758	Jiyoye	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-1.1359669435206556	[407]	[139]	-6	hSpCas9	negative selection	116469
27822445	27822468	8	+	26472758	Jiyoye	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	-0.671481562369125	[244]	[115]	-5	hSpCas9	negative selection	116470
27811072	27811095	8	-	26472758	KBM7	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	-0.09919464166917957	[831,753]	[356,339]	-1	hSpCas9	negative selection	307579
27822428	27822451	8	-	26472758	KBM7	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-1.9478878700095743	[30,75]	[9,3]	-8	hSpCas9	negative selection	307580
27833105	27833128	8	-	26472758	KBM7	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-1.1785335017898724	[1156,762]	[248,148]	-7	hSpCas9	negative selection	307581
27811094	27811117	8	-	26472758	KBM7	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	1.05718909761729	[999,893]	[1175,701]	9	hSpCas9	negative selection	307582
27828143	27828166	8	+	26472758	KBM7	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.5330603994850566	[406,400]	[106,153]	-5	hSpCas9	negative selection	307583
27820564	27820587	8	+	26472758	KBM7	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.25016948734111144	[547,355]	[238,256]	2	hSpCas9	negative selection	307584
27828127	27828150	8	-	26472758	KBM7	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.4601477857788898	[1158,1208]	[851,698]	5	hSpCas9	negative selection	307585
27822458	27822481	8	-	26472758	KBM7	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	1.0830483249092653	[605,695]	[576,726]	9	hSpCas9	negative selection	307586
27828162	27828185	8	+	26472758	KBM7	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.35237106434739635	[854,512]	[409,394]	4	hSpCas9	negative selection	307587
27822445	27822468	8	+	26472758	KBM7	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.4340511689992236	[597,839]	[441,488]	5	hSpCas9	negative selection	307588
27811072	27811095	8	-	26472758	Raji	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	1.0614472512067405	[350]	[169]	8	hSpCas9	negative selection	498697
27822428	27822451	8	-	26472758	Raji	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	0.06785517118696172	[36]	[8]	0	hSpCas9	negative selection	498698
27833105	27833128	8	-	26472758	Raji	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.5255471356391629	[460]	[153]	5	hSpCas9	negative selection	498699
27811094	27811117	8	-	26472758	Raji	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.46196851774231296	[462]	[147]	4	hSpCas9	negative selection	498700
27828143	27828166	8	+	26472758	Raji	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	0.9836481669513547	[145]	[66]	8	hSpCas9	negative selection	498701
27820564	27820587	8	+	26472758	Raji	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.6820777006409287	[187]	[69]	6	hSpCas9	negative selection	498702
27828127	27828150	8	-	26472758	Raji	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.07047284538136611	[672]	[163]	0	hSpCas9	negative selection	498703
27822458	27822481	8	-	26472758	Raji	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	0.9582920373484525	[274]	[123]	8	hSpCas9	negative selection	498704
27828162	27828185	8	+	26472758	Raji	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.3647871950943754	[454]	[81]	-3	hSpCas9	negative selection	498705
27822445	27822468	8	+	26472758	Raji	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.5062108074711843	[357]	[117]	5	hSpCas9	negative selection	498706
27811072	27811095	8	-	26472758	K562	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	0.7999574680477028	[742]	[1091]	6	hSpCas9	negative selection	689815
27822428	27822451	8	-	26472758	K562	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	1.474716347088241	[51]	[121]	9	hSpCas9	negative selection	689816
27833105	27833128	8	-	26472758	K562	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.32905347303863386	[810]	[859]	2	hSpCas9	negative selection	689817
27811094	27811117	8	-	26472758	K562	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.8767490760732621	[748]	[1160]	7	hSpCas9	negative selection	689818
27828143	27828166	8	+	26472758	K562	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	1.031543369598007	[276]	[477]	8	hSpCas9	negative selection	689819
27820564	27820587	8	+	26472758	K562	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.9563724338245799	[383]	[628]	7	hSpCas9	negative selection	689820
27828127	27828150	8	-	26472758	K562	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.3907847135844009	[1076]	[1191]	3	hSpCas9	negative selection	689821
27822458	27822481	8	-	26472758	K562	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	-0.2756691069504118	[336]	[234]	-2	hSpCas9	negative selection	689822
27828162	27828185	8	+	26472758	K562	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.15792214634661816	[652]	[614]	1	hSpCas9	negative selection	689823
27822445	27822468	8	+	26472758	K562	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.844656492726522	[594]	[901]	7	hSpCas9	negative selection	689824
27811143	27811166	8	+	26627737	DLD1	viability	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.1302424233648779	[288]	[44,171,40]	-1	hSpCas9	negative selection	839250
27820580	27820603	8	-	26627737	DLD1	viability	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.5436723948841149	[316]	[207,69,150]	5	hSpCas9	negative selection	839251
27811143	27811166	8	+	26627737	GBM cells	viability after 5 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	0.13429193781661405	[236]	[103,174]	2	hSpCas9	negative selection	921565
27820580	27820603	8	-	26627737	GBM cells	viability after 5 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.39934286539517416	[163]	[146,84]	6	hSpCas9	negative selection	921566
27811143	27811166	8	+	26627737	GBM cells	viability after 13 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.8603335161232251	[236]	[77,64]	-7	hSpCas9	negative selection	1003880
27820580	27820603	8	-	26627737	GBM cells	viability after 13 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.15690488072815095	[163]	[96,100]	2	hSpCas9	negative selection	1003881
27811143	27811166	8	+	26627737	GBM cells	viability after 21 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	0.2672007206745226	[236]	[155,153]	2	hSpCas9	negative selection	1086195
27820580	27820603	8	-	26627737	GBM cells	viability after 21 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.1368751225822148	[163]	[91,70]	-1	hSpCas9	negative selection	1086196
27811143	27811166	8	+	26627737	RPE1	viability after 9 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.5690826836712006	[862]	[113,269]	-4	hSpCas9	negative selection	1168510
27820580	27820603	8	-	26627737	RPE1	viability after 9 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.7340925775349727	[899]	[116,236]	-5	hSpCas9	negative selection	1168511
27811143	27811166	8	+	26627737	RPE1	viability after 12 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.38484967851093627	[862]	[94,264]	-3	hSpCas9	negative selection	1250825
27820580	27820603	8	-	26627737	RPE1	viability after 12 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.8555850830699248	[899]	[137,128]	-5	hSpCas9	negative selection	1250826
27811143	27811166	8	+	26627737	RPE1	viability after 15 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.4784859563286137	[862]	[134,213]	-3	hSpCas9	negative selection	1333140
27820580	27820603	8	-	26627737	RPE1	viability after 15 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.9539823392128481	[899]	[163,99]	-6	hSpCas9	negative selection	1333141
27811143	27811166	8	+	26627737	RPE1	viability after 18 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.910179522801077	[862]	[150,94]	-5	hSpCas9	negative selection	1415455
27820580	27820603	8	-	26627737	RPE1	viability after 18 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.4811694352675662	[899]	[173,173]	-3	hSpCas9	negative selection	1415456
27811143	27811166	8	+	26627737	HeLa	viability after 8 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	0.8734372670805235	[193]	[163,161,140]	7	hSpCas9	negative selection	1497770
27820580	27820603	8	-	26627737	HeLa	viability after 8 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.019191567388683328	[261]	[122,121,95]	0	hSpCas9	negative selection	1497771
27811143	27811166	8	+	26627737	HeLa	viability after 12 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	0.6465625608025352	[193]	[113,164,92]	5	hSpCas9	negative selection	1580085
27820580	27820603	8	-	26627737	HeLa	viability after 12 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.23811358411748657	[261]	[188,88,110]	2	hSpCas9	negative selection	1580086
27811143	27811166	8	+	26627737	HeLa	viability after 15 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.5836017948044343	[193]	[37,46,74]	-5	hSpCas9	negative selection	1662400
27820580	27820603	8	-	26627737	HeLa	viability after 15 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.5324581188737206	[261]	[128,23,66]	-5	hSpCas9	negative selection	1662401
27811143	27811166	8	+	26627737	HeLa	viability after 18 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.5953377318496749	[193]	[22,40,74]	-5	hSpCas9	negative selection	1744715
27820580	27820603	8	-	26627737	HeLa	viability after 18 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.5370207605359646	[261]	[85,19,66]	-5	hSpCas9	negative selection	1744716
27811143	27811166	8	+	26627737	HCT116	viability after 6 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-1.0339859267146934	[516]	[20,49]	-5	hSpCas9	negative selection	1827030
27820580	27820603	8	-	26627737	HCT116	viability after 6 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.8929678982151839	[362]	[143,84]	5	hSpCas9	negative selection	1827031
27811143	27811166	8	+	26627737	HCT116	viability after 8 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.3638666534102063	[311]	[151,105,142]	-4	hSpCas9	negative selection	1909345
27820580	27820603	8	-	26627737	HCT116	viability after 8 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.15854965061622944	[237]	[170,110,71]	-2	hSpCas9	negative selection	1909346
27811143	27811166	8	+	26627737	HCT116	viability after 9 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	0.2756850410839559	[516]	[165,167]	2	hSpCas9	negative selection	1991660
27820580	27820603	8	-	26627737	HCT116	viability after 9 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-1.582278572990224	[362]	[66,4]	-8	hSpCas9	negative selection	1991661
27811143	27811166	8	+	26627737	HCT116	viability after 12 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.8319934080257682	[311]	[55,112,110]	-7	hSpCas9	negative selection	2073975
27820580	27820603	8	-	26627737	HCT116	viability after 12 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.1977131027832965	[237]	[130,98,94]	-2	hSpCas9	negative selection	2073976
27811143	27811166	8	+	26627737	HCT116	viability after 15 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.16077744458685359	[311]	[81,118,268]	-2	hSpCas9	negative selection	2156290
27820580	27820603	8	-	26627737	HCT116	viability after 15 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.25848238655519945	[237]	[162,94,90]	-3	hSpCas9	negative selection	2156291
27811143	27811166	8	+	26627737	HCT116	viability after 18 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.48984717622382734	[311]	[133,29,165]	-4	hSpCas9	negative selection	2238605
27820580	27820603	8	-	26627737	HCT116	viability after 18 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.2522399285914641	[237]	[92,27,176]	-2	hSpCas9	negative selection	2238606
27823063	27823086	8	+	24336569	HL60	viability	CAACAATGTTTGGATGATGAAGG	PBK	ENSG00000168078	0.5015261577606549	[975]	[2923]	4	hSpCas9	negative selection	2282943
27823134	27823157	8	+	24336569	HL60	viability	CGATAATGATCATTACATATAGG	PBK	ENSG00000168078	0.759351824326409	[413]	[1482]	6	hSpCas9	negative selection	2282944
27823174	27823197	8	-	24336569	HL60	viability	AGGTTTGTCTCATTCTCCTTGGG	PBK	ENSG00000168078	0.7756559438012331	[288]	[1046]	6	hSpCas9	negative selection	2282945
27823179	27823202	8	+	24336569	HL60	viability	GGAGAATGAGACAAACCTCTTGG	PBK	ENSG00000168078	0.7612551071810142	[638]	[2291]	6	hSpCas9	negative selection	2282946
27828128	27828151	8	-	24336569	HL60	viability	AGAAGCTTGGCTTTGGTACTGGG	PBK	ENSG00000168078	0.5043448037779563	[1135]	[3409]	4	hSpCas9	negative selection	2282947
27828135	27828158	8	-	24336569	HL60	viability	TTTATGCAGAAGCTTGGCTTTGG	PBK	ENSG00000168078	0.13704357910515041	[849]	[1977]	1	hSpCas9	negative selection	2282948
27828141	27828164	8	-	24336569	HL60	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	1.0344716246737766	[241]	[1048]	7	hSpCas9	negative selection	2282949
27828147	27828170	8	+	24336569	HL60	viability	TTCTGCATAAACGGAGAGGCCGG	PBK	ENSG00000168078	0.5235741768569195	[784]	[2387]	4	hSpCas9	negative selection	2282950
27828162	27828185	8	+	24336569	HL60	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.06126448628323544	[921]	[1869]	0	hSpCas9	negative selection	2282951
27833105	27833128	8	-	24336569	HL60	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.942877859743065	[381]	[1553]	7	hSpCas9	negative selection	2282952
27823063	27823086	8	+	24336569	KBM7	viability	CAACAATGTTTGGATGATGAAGG	PBK	ENSG00000168078	0.5732693605014404	[686]	[2787]	5	hSpCas9	negative selection	2350120
27823134	27823157	8	+	24336569	KBM7	viability	CGATAATGATCATTACATATAGG	PBK	ENSG00000168078	-0.003128969449999519	[351]	[957]	0	hSpCas9	negative selection	2350121
27823174	27823197	8	-	24336569	KBM7	viability	AGGTTTGTCTCATTCTCCTTGGG	PBK	ENSG00000168078	1.5192539395159184	[274]	[2149]	9	hSpCas9	negative selection	2350122
27823179	27823202	8	+	24336569	KBM7	viability	GGAGAATGAGACAAACCTCTTGG	PBK	ENSG00000168078	0.23037871108900976	[790]	[2530]	2	hSpCas9	negative selection	2350123
27828128	27828151	8	-	24336569	KBM7	viability	AGAAGCTTGGCTTTGGTACTGGG	PBK	ENSG00000168078	0.44456481369044987	[884]	[3284]	4	hSpCas9	negative selection	2350124
27828135	27828158	8	-	24336569	KBM7	viability	TTTATGCAGAAGCTTGGCTTTGG	PBK	ENSG00000168078	0.5799015398732245	[610]	[2490]	5	hSpCas9	negative selection	2350125
27828141	27828164	8	-	24336569	KBM7	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.6010738042518879	[327]	[1356]	5	hSpCas9	negative selection	2350126
27828147	27828170	8	+	24336569	KBM7	viability	TTCTGCATAAACGGAGAGGCCGG	PBK	ENSG00000168078	0.8413841349906936	[663]	[3244]	7	hSpCas9	negative selection	2350127
27828162	27828185	8	+	24336569	KBM7	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.6538228356593305	[514]	[2209]	6	hSpCas9	negative selection	2350128
27833105	27833128	8	-	24336569	KBM7	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.09304643622959254	[419]	[1073]	-1	hSpCas9	negative selection	2350129
27811094	27811117	8	-	27260157	DLD1	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.143512161310332	[]	[]	3	hSpCas9	negative selection	2574214
27823063	27823086	8	+	27260157	DLD1	viability	CAACAATGTTTGGATGATGAAGG	PBK	ENSG00000168078	0.562670946747448	[]	[]	8	hSpCas9	negative selection	2575857
27823134	27823157	8	+	27260157	DLD1	viability	CGATAATGATCATTACATATAGG	PBK	ENSG00000168078	-0.274757351547122	[]	[]	-2	hSpCas9	negative selection	2576030
27823179	27823202	8	+	27260157	DLD1	viability	GGAGAATGAGACAAACCTCTTGG	PBK	ENSG00000168078	0.702672660627653	[]	[]	8	hSpCas9	negative selection	2580152
27822438	27822461	8	-	27260157	DLD1	viability	TGGCAGTCTGTGTCTTGCTATGG	PBK	ENSG00000168078	-0.611386601680312	[]	[]	-5	hSpCas9	negative selection	2584224
27828128	27828151	8	-	27260157	DLD1	viability	AGAAGCTTGGCTTTGGTACTGGG	PBK	ENSG00000168078	-0.161643598436632	[]	[]	-1	hSpCas9	negative selection	2586489
27811075	27811098	8	-	27260157	DLD1	viability	ATGGAAACCCAAAGAAGCTGTGG	PBK	ENSG00000168078	0.964550191559851	[]	[]	9	hSpCas9	negative selection	2605894
27828135	27828158	8	-	27260157	DLD1	viability	TTTATGCAGAAGCTTGGCTTTGG	PBK	ENSG00000168078	0.0904077955288113	[]	[]	3	hSpCas9	negative selection	2605909
27828141	27828164	8	-	27260157	DLD1	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.812325842104891	[]	[]	9	hSpCas9	negative selection	2612109
27811104	27811127	8	+	27260157	DLD1	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.787230247466219	[]	[]	8	hSpCas9	negative selection	2614288
27828143	27828166	8	+	27260157	DLD1	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.0681617723813889	[]	[]	0	hSpCas9	negative selection	2615617
27811107	27811130	8	-	27260157	DLD1	viability	GACCCTGAGGCTTGTTACATTGG	PBK	ENSG00000168078	0.0830626531873608	[]	[]	3	hSpCas9	negative selection	2617644
27823174	27823197	8	-	27260157	DLD1	viability	AGGTTTGTCTCATTCTCCTTGGG	PBK	ENSG00000168078	0.376232624992033	[]	[]	4	hSpCas9	negative selection	2618797
27823175	27823198	8	-	27260157	DLD1	viability	GAGGTTTGTCTCATTCTCCTTGG	PBK	ENSG00000168078	-0.572001582958522	[]	[]	-4	hSpCas9	negative selection	2620631
27820580	27820603	8	-	27260157	DLD1	viability	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.332752199872061	[]	[]	4	hSpCas9	negative selection	2620720
27828147	27828170	8	+	27260157	DLD1	viability	TTCTGCATAAACGGAGAGGCCGG	PBK	ENSG00000168078	1.06106376880538	[]	[]	9	hSpCas9	negative selection	2621274
27828127	27828150	8	-	27260157	DLD1	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	-0.876951645493075	[]	[]	-6	hSpCas9	negative selection	2621921
27828162	27828185	8	+	27260157	DLD1	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.263875306072229	[]	[]	4	hSpCas9	negative selection	2644098
27822445	27822468	8	+	27260157	DLD1	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.851792530372408	[]	[]	9	hSpCas9	negative selection	2645192
27833105	27833128	8	-	27260157	DLD1	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.29397413587901	[]	[]	4	hSpCas9	negative selection	2647445
27811094	27811117	8	-	27260157	HT1080	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.693110791727904	[]	[]	6	hSpCas9	negative selection	2650344
27823063	27823086	8	+	27260157	HT1080	viability	CAACAATGTTTGGATGATGAAGG	PBK	ENSG00000168078	0.186515612687904	[]	[]	1	hSpCas9	negative selection	2651987
27823134	27823157	8	+	27260157	HT1080	viability	CGATAATGATCATTACATATAGG	PBK	ENSG00000168078	-1.3248731894918	[]	[]	-9	hSpCas9	negative selection	2652160
27823179	27823202	8	+	27260157	HT1080	viability	GGAGAATGAGACAAACCTCTTGG	PBK	ENSG00000168078	0.19499794078276	[]	[]	1	hSpCas9	negative selection	2656282
27822438	27822461	8	-	27260157	HT1080	viability	TGGCAGTCTGTGTCTTGCTATGG	PBK	ENSG00000168078	-0.338444961709144	[]	[]	-7	hSpCas9	negative selection	2660354
27828128	27828151	8	-	27260157	HT1080	viability	AGAAGCTTGGCTTTGGTACTGGG	PBK	ENSG00000168078	0.367843728136494	[]	[]	3	hSpCas9	negative selection	2662619
27811075	27811098	8	-	27260157	HT1080	viability	ATGGAAACCCAAAGAAGCTGTGG	PBK	ENSG00000168078	0.518074619748064	[]	[]	4	hSpCas9	negative selection	2682024
27828135	27828158	8	-	27260157	HT1080	viability	TTTATGCAGAAGCTTGGCTTTGG	PBK	ENSG00000168078	-0.0729995482957638	[]	[]	0	hSpCas9	negative selection	2682039
27828141	27828164	8	-	27260157	HT1080	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	1.02529848874505	[]	[]	8	hSpCas9	negative selection	2688239
27811104	27811127	8	+	27260157	HT1080	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.633422845923704	[]	[]	5	hSpCas9	negative selection	2690418
27828143	27828166	8	+	27260157	HT1080	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.252959685632829	[]	[]	0	hSpCas9	negative selection	2691747
27811107	27811130	8	-	27260157	HT1080	viability	GACCCTGAGGCTTGTTACATTGG	PBK	ENSG00000168078	0.179539302036984	[]	[]	1	hSpCas9	negative selection	2693774
27823174	27823197	8	-	27260157	HT1080	viability	AGGTTTGTCTCATTCTCCTTGGG	PBK	ENSG00000168078	-1.65295287284409	[]	[]	-9	hSpCas9	negative selection	2694927
27823175	27823198	8	-	27260157	HT1080	viability	GAGGTTTGTCTCATTCTCCTTGG	PBK	ENSG00000168078	0.0121848400705564	[]	[]	0	hSpCas9	negative selection	2696761
27820580	27820603	8	-	27260157	HT1080	viability	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.560361451843599	[]	[]	-7	hSpCas9	negative selection	2696850
27828147	27828170	8	+	27260157	HT1080	viability	TTCTGCATAAACGGAGAGGCCGG	PBK	ENSG00000168078	0.300266981728399	[]	[]	3	hSpCas9	negative selection	2697404
27828127	27828150	8	-	27260157	HT1080	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	-0.496119152627619	[]	[]	-7	hSpCas9	negative selection	2698051
27828162	27828185	8	+	27260157	HT1080	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.235451324244629	[]	[]	2	hSpCas9	negative selection	2720228
27822445	27822468	8	+	27260157	HT1080	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	1.16138144075938	[]	[]	8	hSpCas9	negative selection	2721322
27833105	27833128	8	-	27260157	HT1080	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.0257620475132601	[]	[]	0	hSpCas9	negative selection	2723575
27811094	27811117	8	-	27260157	MKN45	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.371569043689119	[]	[]	6	hSpCas9	negative selection	2726474
27823063	27823086	8	+	27260157	MKN45	viability	CAACAATGTTTGGATGATGAAGG	PBK	ENSG00000168078	0.181401047326263	[]	[]	5	hSpCas9	negative selection	2728117
27823134	27823157	8	+	27260157	MKN45	viability	CGATAATGATCATTACATATAGG	PBK	ENSG00000168078	-1.94404667204098	[]	[]	-9	hSpCas9	negative selection	2728290
27823179	27823202	8	+	27260157	MKN45	viability	GGAGAATGAGACAAACCTCTTGG	PBK	ENSG00000168078	-0.0342365988809842	[]	[]	0	hSpCas9	negative selection	2732412
27822438	27822461	8	-	27260157	MKN45	viability	TGGCAGTCTGTGTCTTGCTATGG	PBK	ENSG00000168078	-0.779729125319355	[]	[]	-7	hSpCas9	negative selection	2736484
27828128	27828151	8	-	27260157	MKN45	viability	AGAAGCTTGGCTTTGGTACTGGG	PBK	ENSG00000168078	-0.401698543813371	[]	[]	-1	hSpCas9	negative selection	2738749
27811075	27811098	8	-	27260157	MKN45	viability	ATGGAAACCCAAAGAAGCTGTGG	PBK	ENSG00000168078	-0.284293064894662	[]	[]	-1	hSpCas9	negative selection	2758154
27828135	27828158	8	-	27260157	MKN45	viability	TTTATGCAGAAGCTTGGCTTTGG	PBK	ENSG00000168078	-0.513469323906048	[]	[]	-6	hSpCas9	negative selection	2758169
27828141	27828164	8	-	27260157	MKN45	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.0790784087259963	[]	[]	0	hSpCas9	negative selection	2764369
27811104	27811127	8	+	27260157	MKN45	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.506405799010262	[]	[]	6	hSpCas9	negative selection	2766548
27828143	27828166	8	+	27260157	MKN45	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.14417457552195	[]	[]	0	hSpCas9	negative selection	2767877
27811107	27811130	8	-	27260157	MKN45	viability	GACCCTGAGGCTTGTTACATTGG	PBK	ENSG00000168078	0.211366717430237	[]	[]	5	hSpCas9	negative selection	2769904
27823174	27823197	8	-	27260157	MKN45	viability	AGGTTTGTCTCATTCTCCTTGGG	PBK	ENSG00000168078	0.294288268843403	[]	[]	5	hSpCas9	negative selection	2771057
27823175	27823198	8	-	27260157	MKN45	viability	GAGGTTTGTCTCATTCTCCTTGG	PBK	ENSG00000168078	0.427249963353344	[]	[]	6	hSpCas9	negative selection	2772891
27820580	27820603	8	-	27260157	MKN45	viability	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.833206969927232	[]	[]	-7	hSpCas9	negative selection	2772980
27828147	27828170	8	+	27260157	MKN45	viability	TTCTGCATAAACGGAGAGGCCGG	PBK	ENSG00000168078	0.204915139283948	[]	[]	5	hSpCas9	negative selection	2773534
27828127	27828150	8	-	27260157	MKN45	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.0547621671244309	[]	[]	0	hSpCas9	negative selection	2774181
27828162	27828185	8	+	27260157	MKN45	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.821835148923964	[]	[]	-7	hSpCas9	negative selection	2796358
27822445	27822468	8	+	27260157	MKN45	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	-1.74781453966552	[]	[]	-9	hSpCas9	negative selection	2797452
27833105	27833128	8	-	27260157	MKN45	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.152852554497588	[]	[]	5	hSpCas9	negative selection	2799705
27811094	27811117	8	-	27260157	RKO	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.442057065791195	[]	[]	2	hSpCas9	negative selection	2802604
27823063	27823086	8	+	27260157	RKO	viability	CAACAATGTTTGGATGATGAAGG	PBK	ENSG00000168078	0.357296363538769	[]	[]	2	hSpCas9	negative selection	2804247
27823134	27823157	8	+	27260157	RKO	viability	CGATAATGATCATTACATATAGG	PBK	ENSG00000168078	-0.712079484690731	[]	[]	-7	hSpCas9	negative selection	2804420
27823179	27823202	8	+	27260157	RKO	viability	GGAGAATGAGACAAACCTCTTGG	PBK	ENSG00000168078	0.886127724086664	[]	[]	8	hSpCas9	negative selection	2808542
27822438	27822461	8	-	27260157	RKO	viability	TGGCAGTCTGTGTCTTGCTATGG	PBK	ENSG00000168078	-0.652875996187994	[]	[]	-7	hSpCas9	negative selection	2812614
27828128	27828151	8	-	27260157	RKO	viability	AGAAGCTTGGCTTTGGTACTGGG	PBK	ENSG00000168078	0.358600194833074	[]	[]	2	hSpCas9	negative selection	2814879
27811075	27811098	8	-	27260157	RKO	viability	ATGGAAACCCAAAGAAGCTGTGG	PBK	ENSG00000168078	0.80387416667499	[]	[]	8	hSpCas9	negative selection	2834284
27828135	27828158	8	-	27260157	RKO	viability	TTTATGCAGAAGCTTGGCTTTGG	PBK	ENSG00000168078	0.33617390720563	[]	[]	1	hSpCas9	negative selection	2834299
27828141	27828164	8	-	27260157	RKO	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	-0.184568073984918	[]	[]	-1	hSpCas9	negative selection	2840499
27811104	27811127	8	+	27260157	RKO	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.506451458381485	[]	[]	2	hSpCas9	negative selection	2842678
27828143	27828166	8	+	27260157	RKO	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	0.409631538971142	[]	[]	2	hSpCas9	negative selection	2844007
27811107	27811130	8	-	27260157	RKO	viability	GACCCTGAGGCTTGTTACATTGG	PBK	ENSG00000168078	-0.156859462447257	[]	[]	0	hSpCas9	negative selection	2846034
27823174	27823197	8	-	27260157	RKO	viability	AGGTTTGTCTCATTCTCCTTGGG	PBK	ENSG00000168078	0.0551795269345633	[]	[]	0	hSpCas9	negative selection	2847187
27823175	27823198	8	-	27260157	RKO	viability	GAGGTTTGTCTCATTCTCCTTGG	PBK	ENSG00000168078	0.21960482275466	[]	[]	1	hSpCas9	negative selection	2849021
27820580	27820603	8	-	27260157	RKO	viability	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.24047298476176	[]	[]	1	hSpCas9	negative selection	2849110
27828147	27828170	8	+	27260157	RKO	viability	TTCTGCATAAACGGAGAGGCCGG	PBK	ENSG00000168078	0.855300503873499	[]	[]	8	hSpCas9	negative selection	2849664
27828127	27828150	8	-	27260157	RKO	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	-0.682958406065677	[]	[]	-7	hSpCas9	negative selection	2850311
27828162	27828185	8	+	27260157	RKO	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.418396362247398	[]	[]	-6	hSpCas9	negative selection	2872488
27822445	27822468	8	+	27260157	RKO	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.396509383150256	[]	[]	2	hSpCas9	negative selection	2873582
27833105	27833128	8	-	27260157	RKO	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.457689582138618	[]	[]	-6	hSpCas9	negative selection	2875835
27811094	27811117	8	-	27260157	SF268	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	-0.0594014145022903	[]	[]	0	hSpCas9	negative selection	2878734
27823063	27823086	8	+	27260157	SF268	viability	CAACAATGTTTGGATGATGAAGG	PBK	ENSG00000168078	0.233425285270998	[]	[]	3	hSpCas9	negative selection	2880377
27823134	27823157	8	+	27260157	SF268	viability	CGATAATGATCATTACATATAGG	PBK	ENSG00000168078	-0.128249823344873	[]	[]	-1	hSpCas9	negative selection	2880550
27823179	27823202	8	+	27260157	SF268	viability	GGAGAATGAGACAAACCTCTTGG	PBK	ENSG00000168078	0.711238542926531	[]	[]	8	hSpCas9	negative selection	2884672
27822438	27822461	8	-	27260157	SF268	viability	TGGCAGTCTGTGTCTTGCTATGG	PBK	ENSG00000168078	0.128996870092155	[]	[]	0	hSpCas9	negative selection	2888744
27828128	27828151	8	-	27260157	SF268	viability	AGAAGCTTGGCTTTGGTACTGGG	PBK	ENSG00000168078	0.109309018964873	[]	[]	0	hSpCas9	negative selection	2891009
27811075	27811098	8	-	27260157	SF268	viability	ATGGAAACCCAAAGAAGCTGTGG	PBK	ENSG00000168078	0.846270321837194	[]	[]	9	hSpCas9	negative selection	2910414
27828135	27828158	8	-	27260157	SF268	viability	TTTATGCAGAAGCTTGGCTTTGG	PBK	ENSG00000168078	0.27108357329215	[]	[]	4	hSpCas9	negative selection	2910429
27828141	27828164	8	-	27260157	SF268	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.281452949290586	[]	[]	4	hSpCas9	negative selection	2916629
27811104	27811127	8	+	27260157	SF268	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.333070470962433	[]	[]	4	hSpCas9	negative selection	2918808
27828143	27828166	8	+	27260157	SF268	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.541377557593347	[]	[]	-4	hSpCas9	negative selection	2920137
27811107	27811130	8	-	27260157	SF268	viability	GACCCTGAGGCTTGTTACATTGG	PBK	ENSG00000168078	0.594681209896999	[]	[]	8	hSpCas9	negative selection	2922164
27823174	27823197	8	-	27260157	SF268	viability	AGGTTTGTCTCATTCTCCTTGGG	PBK	ENSG00000168078	-0.175343468946253	[]	[]	-1	hSpCas9	negative selection	2923317
27823175	27823198	8	-	27260157	SF268	viability	GAGGTTTGTCTCATTCTCCTTGG	PBK	ENSG00000168078	-0.0956462610814381	[]	[]	0	hSpCas9	negative selection	2925151
27820580	27820603	8	-	27260157	SF268	viability	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.286306224636159	[]	[]	4	hSpCas9	negative selection	2925240
27828147	27828170	8	+	27260157	SF268	viability	TTCTGCATAAACGGAGAGGCCGG	PBK	ENSG00000168078	0.452903472285566	[]	[]	7	hSpCas9	negative selection	2925794
27828127	27828150	8	-	27260157	SF268	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.10741907063823	[]	[]	0	hSpCas9	negative selection	2926441
27828162	27828185	8	+	27260157	SF268	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.703985311409343	[]	[]	-5	hSpCas9	negative selection	2948618
27822445	27822468	8	+	27260157	SF268	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.347113966317114	[]	[]	4	hSpCas9	negative selection	2949712
27833105	27833128	8	-	27260157	SF268	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.441178534241832	[]	[]	7	hSpCas9	negative selection	2951965
27828144	27828167	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.5834050459693613	[2,2]	[2,0]	-7	hSpCas9	positive selection	3009812
27833105	27833128	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.1919963462450811	[4,4]	[5,3]	4	hSpCas9	positive selection	3009813
27822428	27822451	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	0.09336674356725216	[5,5]	[5,4]	2	hSpCas9	positive selection	3009814
27823054	27823077	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAAACGTACCAACAATGTTTGG	PBK	ENSG00000168078	-0.197057604268082	[5,5]	[6,1]	-3	hSpCas9	positive selection	3009815
27828144	27828167	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.3197506199289269	[2,2]	[2,0]	-5	hSpCas9	positive selection	3077670
27833105	27833128	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.08366147534643492	[4,4]	[3,2]	1	hSpCas9	positive selection	3077671
27822428	27822451	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	0.17834117870035027	[5,5]	[5,3]	3	hSpCas9	positive selection	3077672
27823054	27823077	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAAACGTACCAACAATGTTTGG	PBK	ENSG00000168078	0.2612417816633082	[5,5]	[4,3]	4	hSpCas9	positive selection	3077673
27820564	27820587		-	24336571	A375	resistance to PLX after 7 days	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	0.2819057863943039	[7,7]	[12,6]	7	hSpCas9	positive selection	3134156
27820564	27820587		+	24336571	A375	resistance to PLX after 7 days	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.11698266806971389	[15,12]	[16,13]	4	hSpCas9	positive selection	3134157
27828162	27828185		+	24336571	A375	resistance to PLX after 7 days	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.19833481804866038	[2,2]	[2,2]	-6	hSpCas9	positive selection	3134158
27828141	27828164		-	24336571	A375	resistance to PLX after 7 days	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.3289715557692182	[9,13]	[14,14]	8	hSpCas9	positive selection	3134160
27820564	27820587		-	24336571	A375	resistance to PLX after 14 days	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	2.07512918253345	[8,7]	[15,19]	9	hSpCas9	positive selection	3191949
27820564	27820587		+	24336571	A375	resistance to PLX after 14 days	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.4147996282753887	[15,8]	[7,6]	4	hSpCas9	positive selection	3191950
27828162	27828185		+	24336571	A375	resistance to PLX after 14 days	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.8812529429791931	[2,1]	[1,1]	7	hSpCas9	positive selection	3191951
27828141	27828164		-	24336571	A375	resistance to PLX after 14 days	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.7992966540622521	[11,13]	[8,11]	6	hSpCas9	positive selection	3191953
27820564	27820587		-	24336571	A375	viability after 7 days	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.6476542575805309	[13]	[7,7]	-7	hSpCas9	negative selection	3249742
27820564	27820587		+	24336571	A375	viability after 7 days	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	-0.11493154065667158	[16]	[15,12]	-2	hSpCas9	negative selection	3249743
27828162	27828185		+	24336571	A375	viability after 7 days	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.44128213871005717	[4]	[2,2]	-6	hSpCas9	negative selection	3249744
27828141	27828164		-	24336571	A375	viability after 7 days	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.20546765870213024	[10]	[9,13]	3	hSpCas9	negative selection	3249746
27820564	27820587		-	24336571	A375	viability after 14 days	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.5433173205482934	[13]	[8,7]	-6	hSpCas9	negative selection	3307535
27820564	27820587		+	24336571	A375	viability after 14 days	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	-0.2899882899756977	[16]	[15,8]	-3	hSpCas9	negative selection	3307536
27828162	27828185		+	24336571	A375	viability after 14 days	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.7263103721131092	[4]	[2,1]	-7	hSpCas9	negative selection	3307537
27828141	27828164		-	24336571	A375	viability after 14 days	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.332758701872613	[10]	[11,13]	4	hSpCas9	negative selection	3307539
27811006	27811029	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	-0.7539010439774191	[257,257]	[0,0]	-5	hSpCas9	positive selection	3384773
27820564	27820587	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	3.087401210003523	[17,17]	[0,0]	8	hSpCas9	positive selection	3384774
27820597	27820620	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.09745487466744575	[142,142]	[0,0]	0	hSpCas9	positive selection	3384775
27828143	27828166	8	+	26780180	HT29	viability (Avana library 4 designs)	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	1.71273650369119	[]	[]	6	hSpCas9	negative selection	3447851
27833105	27833128	8	-	26780180	HT29	viability (Avana library 4 designs)	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.0111398154802992	[]	[]	0	hSpCas9	negative selection	3447852
27822428	27822451	8	-	26780180	HT29	viability (Avana library 4 designs)	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-0.453735784165518	[]	[]	-7	hSpCas9	negative selection	3447853
27823053	27823076	8	+	26780180	HT29	viability (Avana library 4 designs)	TTAAACGTACCAACAATGTTTGG	PBK	ENSG00000168078	-0.398222300373065	[]	[]	-6	hSpCas9	negative selection	3447854
27833105	27833128	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.0224130233175397	[]	[]	0	hSpCas9	negative selection	3541855
27822428	27822451	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-1.09438088387495	[]	[]	-1	hSpCas9	negative selection	3541856
27828143	27828166	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-3.13905148425573	[]	[]	-4	hSpCas9	negative selection	3541857
27823053	27823076	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTAAACGTACCAACAATGTTTGG	PBK	ENSG00000168078	-2.77975319707729	[]	[]	-3	hSpCas9	negative selection	3541858
27823179	27823202	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGAATGAGACAAACCTCTTGG	PBK	ENSG00000168078	-2.03413768980631	[]	[]	-2	hSpCas9	negative selection	3541859
27823174	27823197	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGTTTGTCTCATTCTCCTTGGG	PBK	ENSG00000168078	3.2689364949546	[]	[]	5	hSpCas9	negative selection	3541860
27833105	27833128	8	-	26780180	A375	viability (Avana lentiGuide)	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	1.16420158743387	[]	[]	1	hSpCas9	negative selection	3650514
27822428	27822451	8	-	26780180	A375	viability (Avana lentiGuide)	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-2.21202609640332	[]	[]	-4	hSpCas9	negative selection	3650515
27828143	27828166	8	+	26780180	A375	viability (Avana lentiGuide)	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	12.9890135323121	[]	[]	7	hSpCas9	negative selection	3650516
27823053	27823076	8	+	26780180	A375	viability (Avana lentiGuide)	TTAAACGTACCAACAATGTTTGG	PBK	ENSG00000168078	-5.63036920916663	[]	[]	-8	hSpCas9	negative selection	3650517
27823179	27823202	8	+	26780180	A375	viability (Avana lentiGuide)	GGAGAATGAGACAAACCTCTTGG	PBK	ENSG00000168078	-1.18611001212077	[]	[]	-2	hSpCas9	negative selection	3650518
27823174	27823197	8	-	26780180	A375	viability (Avana lentiGuide)	AGGTTTGTCTCATTCTCCTTGGG	PBK	ENSG00000168078	-3.55956246667409	[]	[]	-6	hSpCas9	negative selection	3650519
27833105	27833128	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.1270761354823018	[6]	[6,4]	-2	hSpCas9	positive selection	3759173
27822428	27822451	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-0.2586384703727915	[7]	[6,4]	-4	hSpCas9	positive selection	3759174
27828143	27828166	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.44359459042864835	[4]	[2,3]	-6	hSpCas9	positive selection	3759175
27823053	27823076	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAAACGTACCAACAATGTTTGG	PBK	ENSG00000168078	-0.11628679077603582	[7]	[7,6]	-2	hSpCas9	positive selection	3759176
27823179	27823202	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGAATGAGACAAACCTCTTGG	PBK	ENSG00000168078	-0.297197267417569	[4]	[3,2]	-4	hSpCas9	positive selection	3759177
27823174	27823197	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGTTTGTCTCATTCTCCTTGGG	PBK	ENSG00000168078	0.17506635163326395	[7]	[8,7]	5	hSpCas9	positive selection	3759178
27833105	27833128	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.00972145912408115	[6]	[4,5]	0	hSpCas9	positive selection	3867780
27822428	27822451	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	0.10831128188527195	[7]	[8,5]	2	hSpCas9	positive selection	3867781
27828143	27828166	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.782526367673551	[3]	[0,1]	-7	hSpCas9	positive selection	3867782
27823053	27823076	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAAACGTACCAACAATGTTTGG	PBK	ENSG00000168078	0.36662563251721936	[6]	[7,7]	9	hSpCas9	positive selection	3867783
27823179	27823202	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGAATGAGACAAACCTCTTGG	PBK	ENSG00000168078	0.23992616192945992	[5]	[5,4]	6	hSpCas9	positive selection	3867784
27823174	27823197	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGTTTGTCTCATTCTCCTTGGG	PBK	ENSG00000168078	0.2833032264564985	[8]	[8,8]	7	hSpCas9	positive selection	3867785
27820597	27820620	8	-	26780180	A375	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.833515909902455	[]	[]	3	hSpCas9	negative selection	3978685
27820564	27820587	8	-	26780180	A375	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	1.0634684012776	[]	[]	5	hSpCas9	negative selection	3978686
27828162	27828185	8	+	26780180	A375	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.726925772643678	[]	[]	2	hSpCas9	negative selection	3978687
27811104	27811127	8	+	26780180	A375	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	1.20423265942777	[]	[]	6	hSpCas9	negative selection	3978688
27811006	27811029	8	+	26780180	A375	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.0187955729358936	[]	[]	0	hSpCas9	negative selection	3978689
27828141	27828164	8	-	26780180	A375	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.463942965011872	[]	[]	1	hSpCas9	negative selection	3978690
27820597	27820620	8	-	26780180	HT29	viability (GeCKOv2 library)	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	1.06655373894568	[]	[]	5	hSpCas9	negative selection	4086651
27820564	27820587	8	-	26780180	HT29	viability (GeCKOv2 library)	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	1.28439016056144	[]	[]	6	hSpCas9	negative selection	4086652
27828162	27828185	8	+	26780180	HT29	viability (GeCKOv2 library)	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.81356732606034	[]	[]	3	hSpCas9	negative selection	4086653
27811104	27811127	8	+	26780180	HT29	viability (GeCKOv2 library)	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	1.42567821358213	[]	[]	7	hSpCas9	negative selection	4086654
27811006	27811029	8	+	26780180	HT29	viability (GeCKOv2 library)	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.182368033016455	[]	[]	0	hSpCas9	negative selection	4086655
27828141	27828164	8	-	26780180	HT29	viability (GeCKOv2 library)	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	-0.259789888872712	[]	[]	-6	hSpCas9	negative selection	4086656
27820564	27820587	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	0.592297356941015	[2]	[1,4]	9	hSpCas9	positive selection	4159029
27820564	27820587	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.08257919092478393	[3]	[2,2]	2	hSpCas9	positive selection	4159030
27828162	27828185	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.1042248286374724	[1]	[1,0]	2	hSpCas9	positive selection	4159031
27828141	27828164	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.29911054688233596	[3]	[2,3]	7	hSpCas9	positive selection	4159033
27820564	27820587	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	0.6633755472456724	[3]	[0,3,0,3]	4	hSpCas9	positive selection	4223051
27820564	27820587	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	1.108088630609612	[3]	[2,1,0,4]	8	hSpCas9	positive selection	4223052
27828162	27828185	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.2660257191170905	[1]	[1,0,0,0]	2	hSpCas9	positive selection	4223053
27828141	27828164	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.007314583239631078	[2]	[0,2,0,0]	0	hSpCas9	positive selection	4223055
27828162	27828185	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.530906179644938	[2]	[3,1]	9	hSpCas9	positive selection	4288980
27828141	27828164	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.3083196845453586	[4]	[4,3]	6	hSpCas9	positive selection	4288981
27811104	27811127	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.01845357409296831	[3]	[2,1]	0	hSpCas9	positive selection	4288982
27811006	27811029	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.1917084965594325	[2]	[3,2]	4	hSpCas9	positive selection	4353232
27820564	27820587	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.08510252437197396	[1]	[2,0]	-2	hSpCas9	positive selection	4353233
27820597	27820620	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.5417749402449861	[2]	[2,4]	9	hSpCas9	positive selection	4353234
27811094	27811116	8	-	27760321	OCIAML3	viability	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.5598392941287099	[465,420]	[443,597]	6	hSpCas9	negative selection	4425832
27822318	27822340	8	-	27760321	OCIAML3	viability	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	-0.7507095091319069	[41,27]	[22,6]	-6	hSpCas9	negative selection	4425833
27822446	27822468	8	+	27760321	OCIAML3	viability	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.8004608225294676	[459,338]	[467,631]	8	hSpCas9	negative selection	4425834
27823108	27823130	8	-	27760321	OCIAML3	viability	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	-1.8331112220604444	[3,4]	[0,0]	-9	hSpCas9	negative selection	4425835
27828141	27828163	8	-	27760321	OCIAML3	viability	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.07041828913042272	[530,382]	[407,323]	0	hSpCas9	negative selection	4425836
27811094	27811116	8	-	27760321	OCIAML2	viability	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	-0.35083380025512223	[465,420]	[227,350]	-4	hSpCas9	negative selection	4509295
27822318	27822340	8	-	27760321	OCIAML2	viability	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	0.8781292870897204	[41,27]	[40,64]	9	hSpCas9	negative selection	4509296
27822446	27822468	8	+	27760321	OCIAML2	viability	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.13802162934024526	[459,338]	[297,423]	1	hSpCas9	negative selection	4509297
27823108	27823130	8	-	27760321	OCIAML2	viability	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	-0.44601776932437787	[3,4]	[3,0]	-5	hSpCas9	negative selection	4509298
27828141	27828163	8	-	27760321	OCIAML2	viability	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.17062706575899667	[530,382]	[398,428]	2	hSpCas9	negative selection	4509299
27811094	27811116	8	-	27760321	MV411	viability	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.39540018345175726	[465,420]	[392,371]	3	hSpCas9	negative selection	4592758
27822318	27822340	8	-	27760321	MV411	viability	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	-4.510531491237764	[41,27]	[0,0]	-9	hSpCas9	negative selection	4592759
27822446	27822468	8	+	27760321	MV411	viability	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.46500838202632766	[459,338]	[320,419]	3	hSpCas9	negative selection	4592760
27823108	27823130	8	-	27760321	MV411	viability	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	-1.5880326531457625	[3,4]	[0,0]	-7	hSpCas9	negative selection	4592761
27828141	27828163	8	-	27760321	MV411	viability	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.9391145313945974	[530,382]	[858,141]	7	hSpCas9	negative selection	4592762
27811094	27811116	8	-	27760321	HL60	viability	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.0719543289802497	[465,420]	[329,433]	0	hSpCas9	negative selection	4676221
27822318	27822340	8	-	27760321	HL60	viability	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	0.09911399402850618	[41,27]	[20,39]	1	hSpCas9	negative selection	4676222
27822446	27822468	8	+	27760321	HL60	viability	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	1.436408446639251	[459,338]	[581,1185]	9	hSpCas9	negative selection	4676223
27823108	27823130	8	-	27760321	HL60	viability	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	1.3893446166209946	[3,4]	[17,0]	9	hSpCas9	negative selection	4676224
27828141	27828163	8	-	27760321	HL60	viability	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.5429652502217348	[530,382]	[503,574]	6	hSpCas9	negative selection	4676225
27811094	27811116	8	-	27760321	HT1080	viability	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.39507174743296375	[420,328]	[142,254]	2	hSpCas9	negative selection	4759684
27822318	27822340	8	-	27760321	HT1080	viability	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	-0.5664124814645493	[27,21]	[0,12]	-3	hSpCas9	negative selection	4759685
27822446	27822468	8	+	27760321	HT1080	viability	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.04086919564563424	[338,264]	[97,151]	0	hSpCas9	negative selection	4759686
27823108	27823130	8	-	27760321	HT1080	viability	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	-0.8443172389209588	[4,3]	[0,0]	-4	hSpCas9	negative selection	4759687
27828141	27828163	8	-	27760321	HT1080	viability	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.35012871140482976	[382,298]	[165,180]	1	hSpCas9	negative selection	4759688
27811094	27811116	8	-	27760321	HT29	viability after 7 days	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	-0.4881881842839709	[420,328]	[360,352,319]	-6	hSpCas9	negative selection	4843147
27822318	27822340	8	-	27760321	HT29	viability after 7 days	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	-1.2376981689248727	[27,21]	[9,4,24]	-9	hSpCas9	negative selection	4843148
27822446	27822468	8	+	27760321	HT29	viability after 7 days	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.45165475980630465	[338,264]	[602,318,675]	7	hSpCas9	negative selection	4843149
27823108	27823130	8	-	27760321	HT29	viability after 7 days	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	-1.775192247223476	[4,3]	[0,2,0]	-9	hSpCas9	negative selection	4843150
27828141	27828163	8	-	27760321	HT29	viability after 7 days	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.45513262812092564	[382,298]	[822,538,475]	7	hSpCas9	negative selection	4843151
27811094	27811116	8	-	27760321	HT29	viability after 25 days	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.5147849387913611	[420,328]	[570,506,777]	5	hSpCas9	negative selection	4926610
27822318	27822340	8	-	27760321	HT29	viability after 25 days	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	0.4226599730175544	[27,21]	[60,17,33]	4	hSpCas9	negative selection	4926611
27822446	27822468	8	+	27760321	HT29	viability after 25 days	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	-0.0783975525192721	[338,264]	[307,444,216]	-1	hSpCas9	negative selection	4926612
27823108	27823130	8	-	27760321	HT29	viability after 25 days	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	1.1984784269457727	[4,3]	[0,32,0]	9	hSpCas9	negative selection	4926613
27828141	27828163	8	-	27760321	HT29	viability after 25 days	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.718748277444086	[382,298]	[538,667,731]	7	hSpCas9	negative selection	4926614
27811094	27811116	8	-	27760321	HT29	viability after 22 days	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	-0.0839609706608107	[420,328]	[300,522,405]	-1	hSpCas9	negative selection	5010073
27822318	27822340	8	-	27760321	HT29	viability after 22 days	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	-0.4808959562928332	[27,21]	[24,19,16]	-4	hSpCas9	negative selection	5010074
27822446	27822468	8	+	27760321	HT29	viability after 22 days	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.5076796555566732	[338,264]	[559,486,439]	5	hSpCas9	negative selection	5010075
27823108	27823130	8	-	27760321	HT29	viability after 22 days	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	1.0704660700030777	[4,3]	[0,30,0]	9	hSpCas9	negative selection	5010076
27828141	27828163	8	-	27760321	HT29	viability after 22 days	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.9266173912636946	[382,298]	[977,702,558]	9	hSpCas9	negative selection	5010077
27811094	27811116	8	-	27760321	HT29	viability after 19 days	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.6476359461763658	[420,328]	[617,432,947]	6	hSpCas9	negative selection	5093536
27822318	27822340	8	-	27760321	HT29	viability after 19 days	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	-2.3304866795963624	[27,21]	[5,2,7]	-8	hSpCas9	negative selection	5093537
27822446	27822468	8	+	27760321	HT29	viability after 19 days	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.07815243100300931	[338,264]	[383,514,202]	0	hSpCas9	negative selection	5093538
27823108	27823130	8	-	27760321	HT29	viability after 19 days	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	-2.365478083203529	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	5093539
27828141	27828163	8	-	27760321	HT29	viability after 19 days	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.9666440186863146	[382,298]	[720,1047,521]	8	hSpCas9	negative selection	5093540
27811094	27811116	8	-	27760321	HT29	viability after 16 days	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.11581156293872122	[420,328]	[586,354,436]	1	hSpCas9	negative selection	5176999
27822318	27822340	8	-	27760321	HT29	viability after 16 days	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	0.9137647417895058	[27,21]	[144,8,13]	9	hSpCas9	negative selection	5177000
27822446	27822468	8	+	27760321	HT29	viability after 16 days	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.31516345875250995	[338,264]	[393,637,220]	3	hSpCas9	negative selection	5177001
27823108	27823130	8	-	27760321	HT29	viability after 16 days	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	-2.334013630782607	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	5177002
27828141	27828163	8	-	27760321	HT29	viability after 16 days	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.6951903656237355	[382,298]	[695,404,764]	7	hSpCas9	negative selection	5177003
27811094	27811116	8	-	27760321	HT29	viability after 13 days	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	-0.27646185202753765	[420,328]	[298,475,305]	-3	hSpCas9	negative selection	5260462
27822318	27822340	8	-	27760321	HT29	viability after 13 days	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	0.9441377677495244	[27,21]	[88,32,45]	9	hSpCas9	negative selection	5260463
27822446	27822468	8	+	27760321	HT29	viability after 13 days	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.43483073617510476	[338,264]	[255,651,510]	5	hSpCas9	negative selection	5260464
27823108	27823130	8	-	27760321	HT29	viability after 13 days	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	-2.386301030226745	[4,3]	[0,0,0]	-9	hSpCas9	negative selection	5260465
27828141	27828163	8	-	27760321	HT29	viability after 13 days	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.7472106531183047	[382,298]	[634,640,712]	8	hSpCas9	negative selection	5260466
27811094	27811116	8	-	27760321	HT29	viability after 10 days	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.28652296975001434	[420,328]	[675,518,517]	4	hSpCas9	negative selection	5343925
27822318	27822340	8	-	27760321	HT29	viability after 10 days	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	-0.6685103090142257	[27,21]	[14,22,20]	-7	hSpCas9	negative selection	5343926
27822446	27822468	8	+	27760321	HT29	viability after 10 days	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.4049835368663227	[338,264]	[489,706,310]	5	hSpCas9	negative selection	5343927
27823108	27823130	8	-	27760321	HT29	viability after 10 days	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	-2.492312337387089	[4,3]	[0,0,0]	-9	hSpCas9	negative selection	5343928
27828141	27828163	8	-	27760321	HT29	viability after 10 days	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.4110845948049085	[382,298]	[420,644,632]	5	hSpCas9	negative selection	5343929
27811094	27811116	8	-	27760321	MOLM13	viability	TTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.6882264073376603	[465,420]	[384,417]	5	hSpCas9	negative selection	5427388
27822318	27822340	8	-	27760321	MOLM13	viability	AATATGGCAAGAGGGTTAAAGG	PBK	ENSG00000168078	1.6956075321875717	[41,27]	[121,12]	9	hSpCas9	negative selection	5427389
27822446	27822468	8	+	27760321	MOLM13	viability	AGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	-0.7281760310429888	[459,338]	[69,189]	-4	hSpCas9	negative selection	5427390
27823108	27823130	8	-	27760321	MOLM13	viability	GTGTATCAAAAGAGACTAATGG	PBK	ENSG00000168078	-1.3619758403181672	[3,4]	[0,0]	-7	hSpCas9	negative selection	5427391
27828141	27828163	8	-	27760321	MOLM13	viability	CTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	1.271255467950385	[530,382]	[896,376]	8	hSpCas9	negative selection	5427392
27837310	27837333	8	+	27661255	K562	viability	GACAAAGCTACGACGCGGACGGG	PBK	ENSG00000168078	-0.04211327716793145	[1013,836]	[767,679]	-2	dCas9-KRAB	negative selection	5500332
27837393	27837416	8	+	27661255	K562	viability	GTAGATGTAGAAACTCCAAGGGG	PBK	ENSG00000168078	0.05622411226782753	[2004,2186]	[1959,1548]	2	dCas9-KRAB	negative selection	5500333
27837735	27837758	8	-	27661255	K562	viability	GCAGCTGCAGGGTCTCGCTGGGG	PBK	ENSG00000168078	-0.7025650703440731	[191,162]	[88,85]	-8	dCas9-KRAB	negative selection	5500334
27837757	27837780	8	-	27661255	K562	viability	GGCGTATGTGTTGGTGCTAGAGG	PBK	ENSG00000168078	0.19240662250149757	[692,523]	[656,473]	6	dCas9-KRAB	negative selection	5500335
27828162	27828185	8	+	27260156	BXPC3	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.22682877694313053	[203]	[231,339,200,214]	5	hSpCas9	negative selection	5561440
27828141	27828164	8	-	27260156	BXPC3	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.15489265628964044	[1159]	[1192,1238,1446,1564]	3	hSpCas9	negative selection	5561441
27811104	27811127	8	+	27260156	BXPC3	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.2830965248258365	[485]	[560,591,692,633]	6	hSpCas9	negative selection	5561442
27811006	27811029	8	+	27260156	BXPC3	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.5593397246687284	[447]	[575,709,811,668]	9	hSpCas9	negative selection	5625692
27820564	27820587	8	-	27260156	BXPC3	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.6665834132413482	[129]	[78,90,105,63]	-8	hSpCas9	negative selection	5625693
27820597	27820620	8	-	27260156	BXPC3	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.07200693023466223	[453]	[385,411,405,629]	-2	hSpCas9	negative selection	5625694
27828162	27828185	8	+	27260156	A673	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.02409814676148514	[203]	[287,161,238,283]	0	hSpCas9	negative selection	5682691
27828141	27828164	8	-	27260156	A673	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.13637395968184673	[1159]	[1770,1399,1501,1475]	3	hSpCas9	negative selection	5682692
27811104	27811127	8	+	27260156	A673	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.1301167683106253	[485]	[800,613,544,611]	3	hSpCas9	negative selection	5682693
27811006	27811029	8	+	27260156	A673	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.6365183261228942	[447]	[844,765,979,748]	9	hSpCas9	negative selection	5746943
27820564	27820587	8	-	27260156	A673	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.6916083780697069	[129]	[135,109,77,64]	-9	hSpCas9	negative selection	5746944
27820597	27820620	8	-	27260156	A673	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.28652867354213685	[453]	[599,358,360,489]	-6	hSpCas9	negative selection	5746945
27828162	27828185	8	+	27260156	A375	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.10494066823697157	[203]	[320,319,206,192]	1	hSpCas9	negative selection	5803942
27828141	27828164	8	-	27260156	A375	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.28001581154442867	[1159]	[1636,1764,1676,1525]	4	hSpCas9	negative selection	5803943
27811104	27811127	8	+	27260156	A375	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.3371351393982763	[485]	[702,769,915,508]	5	hSpCas9	negative selection	5803944
27811006	27811029	8	+	27260156	A375	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.5850514242053303	[447]	[703,832,785,815]	8	hSpCas9	negative selection	5868194
27820564	27820587	8	-	27260156	A375	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.3644913846744988	[129]	[143,69,152,99]	-5	hSpCas9	negative selection	5868195
27820597	27820620	8	-	27260156	A375	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.1217002184107798	[453]	[550,608,354,453]	-2	hSpCas9	negative selection	5868196
27828162	27828185	8	+	27260156	COLO741	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.02447642829752139	[203]	[141,299,336]	0	hSpCas9	negative selection	5925193
27828141	27828164	8	-	27260156	COLO741	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.21277462836675975	[1159]	[1858,1641,1663]	4	hSpCas9	negative selection	5925194
27811104	27811127	8	+	27260156	COLO741	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	-0.012717851162354223	[485]	[862,447,558]	0	hSpCas9	negative selection	5925195
27811006	27811029	8	+	27260156	COLO741	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.34527653560192606	[447]	[797,565,814]	7	hSpCas9	negative selection	5989445
27820564	27820587	8	-	27260156	COLO741	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.649428849414688	[129]	[81,120,111]	-8	hSpCas9	negative selection	5989446
27820597	27820620	8	-	27260156	COLO741	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.17623329952210753	[453]	[539,554,450]	-4	hSpCas9	negative selection	5989447
27828162	27828185	8	+	27260156	CAL120	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.13684007112819985	[203]	[375,207,267]	2	hSpCas9	negative selection	6046444
27828141	27828164	8	-	27260156	CAL120	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.2276702269139934	[1159]	[1860,1168,2058]	3	hSpCas9	negative selection	6046445
27811104	27811127	8	+	27260156	CAL120	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.7499973804100586	[485]	[1333,939,827]	9	hSpCas9	negative selection	6046446
27811006	27811029	8	+	27260156	CAL120	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.44348859030023796	[447]	[777,850,649]	6	hSpCas9	negative selection	6110696
27820564	27820587	8	-	27260156	CAL120	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.0817054184503927	[129]	[119,259,74]	-1	hSpCas9	negative selection	6110697
27820597	27820620	8	-	27260156	CAL120	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.2161271949711547	[453]	[495,404,557]	-3	hSpCas9	negative selection	6110698
27828162	27828185	8	+	27260156	CADOES1	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.1324657914136087	[203]	[123,169,304,233]	2	hSpCas9	negative selection	6167695
27828141	27828164	8	-	27260156	CADOES1	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.28551874400074895	[1159]	[1245,1028,1424,1568]	5	hSpCas9	negative selection	6167696
27811104	27811127	8	+	27260156	CADOES1	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.22547713978377787	[485]	[493,599,494,524]	4	hSpCas9	negative selection	6167697
27811006	27811029	8	+	27260156	CADOES1	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.7898331218946953	[447]	[637,747,665,833]	9	hSpCas9	negative selection	6231947
27820564	27820587	8	-	27260156	CADOES1	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.5534844571793955	[129]	[69,40,96,122]	-7	hSpCas9	negative selection	6231948
27820597	27820620	8	-	27260156	CADOES1	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.14659361386489086	[453]	[310,380,425,408]	-3	hSpCas9	negative selection	6231949
27828162	27828185	8	+	27260156	EWS502	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.0726474523504903	[203]	[115,249,280,277]	1	hSpCas9	negative selection	6288946
27828141	27828164	8	-	27260156	EWS502	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.267301605164586	[1159]	[1395,1314,1234,2014]	5	hSpCas9	negative selection	6288947
27811104	27811127	8	+	27260156	EWS502	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.2611929139560862	[485]	[544,647,653,626]	4	hSpCas9	negative selection	6288948
27811006	27811029	8	+	27260156	EWS502	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.5653260756434729	[447]	[621,592,790,823]	8	hSpCas9	negative selection	6353198
27820564	27820587	8	-	27260156	EWS502	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	0.04467507115643654	[129]	[60,68,96,368]	0	hSpCas9	negative selection	6353199
27820597	27820620	8	-	27260156	EWS502	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.3311063659425721	[453]	[448,360,383,321]	-5	hSpCas9	negative selection	6353200
27828162	27828185	8	+	27260156	EW8	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.41880675590762817	[203]	[282,277,147,193]	7	hSpCas9	negative selection	6410197
27828141	27828164	8	-	27260156	EW8	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.17892315295086147	[1159]	[1147,1035,979,1112]	3	hSpCas9	negative selection	6410198
27811104	27811127	8	+	27260156	EW8	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.32902119697174737	[485]	[672,431,417,486]	6	hSpCas9	negative selection	6410199
27811006	27811029	8	+	27260156	EW8	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.6861066379743701	[447]	[751,665,328,649]	9	hSpCas9	negative selection	6474449
27820564	27820587	8	-	27260156	EW8	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	1.4536505110141829	[129]	[123,38,809,72]	9	hSpCas9	negative selection	6474450
27820597	27820620	8	-	27260156	EW8	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.06757602882984126	[453]	[420,404,276,320]	-1	hSpCas9	negative selection	6474451
27828162	27828185	8	+	27260156	CORL105	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.1427098513031657	[203]	[262,344,180,250]	2	hSpCas9	negative selection	6531448
27828141	27828164	8	-	27260156	CORL105	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.303954267968914	[1159]	[1841,1529,1726,1622]	5	hSpCas9	negative selection	6531449
27811104	27811127	8	+	27260156	CORL105	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.3181995477400399	[485]	[674,795,774,598]	6	hSpCas9	negative selection	6531450
27811006	27811029	8	+	27260156	CORL105	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.5538443023834823	[447]	[838,637,1056,595]	8	hSpCas9	negative selection	6595700
27820564	27820587	8	-	27260156	CORL105	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.3055040797104669	[129]	[107,115,128,139]	-5	hSpCas9	negative selection	6595701
27820597	27820620	8	-	27260156	CORL105	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.3301314675934013	[453]	[279,424,569,433]	-6	hSpCas9	negative selection	6595702
27828162	27828185	8	+	27260156	HS294T	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.09603710195684156	[203]	[83,77,56,74]	-1	hSpCas9	negative selection	6652699
27828141	27828164	8	-	27260156	HS294T	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.1386450447143046	[1159]	[528,458,429,564]	2	hSpCas9	negative selection	6652700
27811104	27811127	8	+	27260156	HS294T	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.3748811593519038	[485]	[202,196,297,288]	5	hSpCas9	negative selection	6652701
27811006	27811029	8	+	27260156	HS294T	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.6342358099416918	[447]	[157,201,211,564]	8	hSpCas9	negative selection	6716951
27820564	27820587	8	-	27260156	HS294T	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.3186794967873905	[129]	[39,65,29,20]	-4	hSpCas9	negative selection	6716952
27820597	27820620	8	-	27260156	HS294T	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.46748371680653206	[453]	[115,125,146,117]	-6	hSpCas9	negative selection	6716953
27828162	27828185	8	+	27260156	HCC44	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.20350463510457772	[203]	[453,206,262,164]	3	hSpCas9	negative selection	6773950
27828141	27828164	8	-	27260156	HCC44	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.159675315352229	[1159]	[1751,1091,1869,1290]	2	hSpCas9	negative selection	6773951
27811104	27811127	8	+	27260156	HCC44	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.14758772810846163	[485]	[740,443,648,637]	2	hSpCas9	negative selection	6773952
27811006	27811029	8	+	27260156	HCC44	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.32171967828661074	[447]	[689,717,678,447]	5	hSpCas9	negative selection	6838202
27820564	27820587	8	-	27260156	HCC44	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.9738004800341102	[129]	[44,46,93,115]	-8	hSpCas9	negative selection	6838203
27820597	27820620	8	-	27260156	HCC44	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.042634738799489015	[453]	[605,424,714,307]	0	hSpCas9	negative selection	6838204
27828162	27828185	8	+	27260156	G402	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.3179343892101252	[203]	[304,200,101,204]	-4	hSpCas9	negative selection	6895201
27828141	27828164	8	-	27260156	G402	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.22443920984627774	[1159]	[2352,1680,1491,1206]	3	hSpCas9	negative selection	6895202
27811104	27811127	8	+	27260156	G402	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.4643064405442915	[485]	[1340,956,426,636]	6	hSpCas9	negative selection	6895203
27811006	27811029	8	+	27260156	G402	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.9213731879128105	[447]	[988,689,1555,882]	9	hSpCas9	negative selection	6959453
27820564	27820587	8	-	27260156	G402	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.8125674180789944	[129]	[70,84,72,126]	-7	hSpCas9	negative selection	6959454
27820597	27820620	8	-	27260156	G402	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.25818397630150625	[453]	[372,817,786,637]	3	hSpCas9	negative selection	6959455
27828162	27828185	8	+	27260156	L33	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.27573399116201613	[203]	[209,114,153,252]	6	hSpCas9	negative selection	7016452
27828141	27828164	8	-	27260156	L33	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.1352833944758829	[1159]	[1156,545,813,1313]	3	hSpCas9	negative selection	7016453
27811104	27811127	8	+	27260156	L33	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.2372045058623452	[485]	[625,196,470,435]	5	hSpCas9	negative selection	7016454
27811006	27811029	8	+	27260156	L33	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.18880654092764	[447]	[512,184,279,630]	4	hSpCas9	negative selection	7080704
27820564	27820587	8	-	27260156	L33	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	0.1581841805997759	[129]	[98,70,41,240]	3	hSpCas9	negative selection	7080705
27820597	27820620	8	-	27260156	L33	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.3391713517041862	[453]	[370,135,270,301]	-7	hSpCas9	negative selection	7080706
27828162	27828185	8	+	27260156	K562	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.34952053351528956	[203]	[335,329,250,40]	4	hSpCas9	negative selection	7137703
27828141	27828164	8	-	27260156	K562	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.4964651388386063	[1159]	[1735,1578,1209,1322]	6	hSpCas9	negative selection	7137704
27811104	27811127	8	+	27260156	K562	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.09483032233733676	[485]	[821,516,337,223]	1	hSpCas9	negative selection	7137705
27811006	27811029	8	+	27260156	K562	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.3357857833032659	[447]	[556,807,389,294]	4	hSpCas9	negative selection	7201955
27820564	27820587	8	-	27260156	K562	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	0.10581287335704626	[129]	[113,8,296,74]	1	hSpCas9	negative selection	7201956
27820597	27820620	8	-	27260156	K562	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.22822296866181221	[453]	[223,452,318,370]	-3	hSpCas9	negative selection	7201957
27828162	27828185	8	+	27260156	HT29	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.3386979593165922	[203]	[232,407,334,281]	6	hSpCas9	negative selection	7258954
27828141	27828164	8	-	27260156	HT29	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.3137509135342196	[1159]	[1851,1752,1642,1756]	6	hSpCas9	negative selection	7258955
27811104	27811127	8	+	27260156	HT29	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.42321452498201406	[485]	[680,787,927,760]	7	hSpCas9	negative selection	7258956
27811006	27811029	8	+	27260156	HT29	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.5293431206894925	[447]	[921,775,763,696]	8	hSpCas9	negative selection	7323206
27820564	27820587	8	-	27260156	HT29	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.3346087484057174	[129]	[147,181,60,116]	-6	hSpCas9	negative selection	7323207
27820597	27820620	8	-	27260156	HT29	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.18114707018522352	[453]	[771,750,637,388]	3	hSpCas9	negative selection	7323208
27828162	27828185	8	+	27260156	MHHES1	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.42271011262921276	[203]	[267,462,403,140]	7	hSpCas9	negative selection	7380205
27828141	27828164	8	-	27260156	MHHES1	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.1378285993375361	[1159]	[1503,1547,1309,1384]	2	hSpCas9	negative selection	7380206
27811104	27811127	8	+	27260156	MHHES1	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.29029124179244875	[485]	[1051,475,695,503]	5	hSpCas9	negative selection	7380207
27811006	27811029	8	+	27260156	MHHES1	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.32810455206846006	[447]	[654,625,643,602]	6	hSpCas9	negative selection	7444457
27820564	27820587	8	-	27260156	MHHES1	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.2181533997719478	[129]	[236,53,51,155]	-4	hSpCas9	negative selection	7444458
27820597	27820620	8	-	27260156	MHHES1	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.109746944016503	[453]	[559,484,551,332]	-2	hSpCas9	negative selection	7444459
27828162	27828185	8	+	27260156	MEWO	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.18352739146479013	[203]	[235,199,217]	4	hSpCas9	negative selection	7501456
27828141	27828164	8	-	27260156	MEWO	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	-0.0016274654550965106	[1159]	[1209,929,1136]	0	hSpCas9	negative selection	7501457
27811104	27811127	8	+	27260156	MEWO	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.4102250942471859	[485]	[579,572,654]	8	hSpCas9	negative selection	7501458
27811006	27811029	8	+	27260156	MEWO	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.4063227768850213	[447]	[587,474,609]	8	hSpCas9	negative selection	7565708
27820564	27820587	8	-	27260156	MEWO	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.3134141841647671	[129]	[115,120,59]	-6	hSpCas9	negative selection	7565709
27820597	27820620	8	-	27260156	MEWO	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.15862423494632452	[453]	[465,387,303]	-3	hSpCas9	negative selection	7565710
27828162	27828185	8	+	27260156	LNCAPCLONEFGC	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.1285394451152455	[203]	[164,155,222,140]	-2	hSpCas9	negative selection	7622707
27828141	27828164	8	-	27260156	LNCAPCLONEFGC	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.23906544706381494	[1159]	[1161,1084,1491,1269]	4	hSpCas9	negative selection	7622708
27811104	27811127	8	+	27260156	LNCAPCLONEFGC	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.6444805236379325	[485]	[812,536,749,668]	8	hSpCas9	negative selection	7622709
27811006	27811029	8	+	27260156	LNCAPCLONEFGC	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.7447320865730366	[447]	[654,675,818,590]	9	hSpCas9	negative selection	7686959
27820564	27820587	8	-	27260156	LNCAPCLONEFGC	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.44733058472585907	[129]	[50,143,70,73]	-6	hSpCas9	negative selection	7686960
27820597	27820620	8	-	27260156	LNCAPCLONEFGC	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.3630484059284852	[453]	[285,319,383,298]	-5	hSpCas9	negative selection	7686961
27828162	27828185	8	+	27260156	PANC0327	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.20955084389527934	[203]	[134,241,298,151]	3	hSpCas9	negative selection	7743958
27828141	27828164	8	-	27260156	PANC0327	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.3134387967994283	[1159]	[1530,980,1405,1262]	4	hSpCas9	negative selection	7743959
27811104	27811127	8	+	27260156	PANC0327	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.3204956890035743	[485]	[394,587,494,659]	5	hSpCas9	negative selection	7743960
27811006	27811029	8	+	27260156	PANC0327	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.6710979007719582	[447]	[479,678,645,710]	8	hSpCas9	negative selection	7808210
27820564	27820587	8	-	27260156	PANC0327	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-1.2941644134981065	[129]	[56,55,38,35]	-9	hSpCas9	negative selection	7808211
27820597	27820620	8	-	27260156	PANC0327	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.29529851765609266	[453]	[504,431,351,698]	4	hSpCas9	negative selection	7808212
27828162	27828185	8	+	27260156	NCIH2009	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.1853803527725464	[203]	[351,448,173]	2	hSpCas9	negative selection	7865209
27828141	27828164	8	-	27260156	NCIH2009	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.24534973324862253	[1159]	[1804,2263,1661]	3	hSpCas9	negative selection	7865210
27811104	27811127	8	+	27260156	NCIH2009	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	-0.06074045683991672	[485]	[812,649,520]	-1	hSpCas9	negative selection	7865211
27811006	27811029	8	+	27260156	NCIH2009	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.2999195804641223	[447]	[594,862,815]	4	hSpCas9	negative selection	7929461
27820564	27820587	8	-	27260156	NCIH2009	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	0.04972572723008417	[129]	[330,184,75]	0	hSpCas9	negative selection	7929462
27820597	27820620	8	-	27260156	NCIH2009	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.19611888749572837	[453]	[526,544,582]	-3	hSpCas9	negative selection	7929463
27828162	27828185	8	+	27260156	NCIH1373	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.3397185573710081	[203]	[459,101,234,108]	3	hSpCas9	negative selection	7986460
27828141	27828164	8	-	27260156	NCIH1373	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.7781671198845643	[1159]	[1948,1950,2405,684]	7	hSpCas9	negative selection	7986461
27811104	27811127	8	+	27260156	NCIH1373	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.7720488872428704	[485]	[702,864,985,300]	7	hSpCas9	negative selection	7986462
27811006	27811029	8	+	27260156	NCIH1373	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.9820685384363362	[447]	[1281,1531,641,122]	8	hSpCas9	negative selection	8050712
27820564	27820587	8	-	27260156	NCIH1373	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.1418955713730079	[129]	[161,156,102,27]	-1	hSpCas9	negative selection	8050713
27820597	27820620	8	-	27260156	NCIH1373	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.07670613448659032	[453]	[250,577,857,102]	0	hSpCas9	negative selection	8050714
27828162	27828185	8	+	27260156	PATU8902	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.33930685687221207	[203]	[575,496,216,154]	3	hSpCas9	negative selection	8107711
27828141	27828164	8	-	27260156	PATU8902	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.683460878756776	[1159]	[2353,2627,1678,4119]	7	hSpCas9	negative selection	8107712
27811104	27811127	8	+	27260156	PATU8902	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.9040850708160446	[485]	[1990,842,1390,722]	8	hSpCas9	negative selection	8107713
27811006	27811029	8	+	27260156	PATU8902	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	1.034523587325233	[447]	[1002,1309,1365,1420]	9	hSpCas9	negative selection	8171963
27820564	27820587	8	-	27260156	PATU8902	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.20460988326670093	[129]	[77,161,180,206]	-2	hSpCas9	negative selection	8171964
27820597	27820620	8	-	27260156	PATU8902	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.33772784350681	[453]	[938,692,313,1444]	3	hSpCas9	negative selection	8171965
27828162	27828185	8	+	27260156	PANC1	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.3878995252848294	[203]	[188,285,315,148]	6	hSpCas9	negative selection	8228962
27828141	27828164	8	-	27260156	PANC1	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.38034857632776786	[1159]	[1372,1660,1244,1007]	6	hSpCas9	negative selection	8228963
27811104	27811127	8	+	27260156	PANC1	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.9842468950422725	[485]	[888,973,854,632]	9	hSpCas9	negative selection	8228964
27811006	27811029	8	+	27260156	PANC1	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.4197460036760628	[447]	[562,693,369,465]	6	hSpCas9	negative selection	8293214
27820564	27820587	8	-	27260156	PANC1	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.6064668339842532	[129]	[143,48,70,28]	-7	hSpCas9	negative selection	8293215
27820597	27820620	8	-	27260156	PANC1	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.09654713845073049	[453]	[259,349,696,355]	1	hSpCas9	negative selection	8293216
27828162	27828185	8	+	27260156	PANC0813	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.5812496905531961	[203]	[292,381,349,399]	8	hSpCas9	negative selection	8350213
27828141	27828164	8	-	27260156	PANC0813	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.2958606658036278	[1159]	[1810,1627,1630,1632]	5	hSpCas9	negative selection	8350214
27811104	27811127	8	+	27260156	PANC0813	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.36322957701104147	[485]	[611,895,846,578]	6	hSpCas9	negative selection	8350215
27811006	27811029	8	+	27260156	PANC0813	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.5160024097463692	[447]	[581,771,823,811]	8	hSpCas9	negative selection	8414465
27820564	27820587	8	-	27260156	PANC0813	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	0.05736245420357089	[129]	[113,166,202,147]	0	hSpCas9	negative selection	8414466
27820597	27820620	8	-	27260156	PANC0813	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.16587134601004533	[453]	[537,428,507,433]	-3	hSpCas9	negative selection	8414467
27828162	27828185	8	+	27260156	RDES	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.14057911583271965	[203]	[230,241,218,354]	2	hSpCas9	negative selection	8471464
27828141	27828164	8	-	27260156	RDES	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.02156808460576376	[1159]	[1127,1388,1518,1395]	0	hSpCas9	negative selection	8471465
27811104	27811127	8	+	27260156	RDES	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.19229248556648953	[485]	[514,764,629,637]	3	hSpCas9	negative selection	8471466
27811006	27811029	8	+	27260156	RDES	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.505138051051784	[447]	[632,729,631,958]	7	hSpCas9	negative selection	8535716
27820564	27820587	8	-	27260156	RDES	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.60736532071179	[129]	[117,115,74,67]	-8	hSpCas9	negative selection	8535717
27820597	27820620	8	-	27260156	RDES	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.5417303327783677	[453]	[313,245,487,408]	-7	hSpCas9	negative selection	8535718
27828162	27828185	8	+	27260156	PC3	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.33823140082054126	[203]	[209,248,297,276]	7	hSpCas9	negative selection	8592715
27828141	27828164	8	-	27260156	PC3	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.20729042032339096	[1159]	[854,1343,2234,1332]	4	hSpCas9	negative selection	8592716
27811104	27811127	8	+	27260156	PC3	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.14892286449842848	[485]	[355,400,1125,527]	3	hSpCas9	negative selection	8592717
27811006	27811029	8	+	27260156	PC3	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.255091516296754	[447]	[249,539,893,677]	5	hSpCas9	negative selection	8656967
27820564	27820587	8	-	27260156	PC3	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-1.0698065903220908	[129]	[66,36,139,20]	-9	hSpCas9	negative selection	8656968
27820597	27820620	8	-	27260156	PC3	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.02209690983401621	[453]	[275,401,848,505]	0	hSpCas9	negative selection	8656969
27828162	27828185	8	+	27260156	PATU8988T	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.16881107380396543	[203]	[102,340,293,152]	3	hSpCas9	negative selection	8713966
27828141	27828164	8	-	27260156	PATU8988T	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	-0.1450341705437339	[1159]	[947,817,1037,1250]	-2	hSpCas9	negative selection	8713967
27811104	27811127	8	+	27260156	PATU8988T	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.48076364220852075	[485]	[559,542,859,643]	7	hSpCas9	negative selection	8713968
27811006	27811029	8	+	27260156	PATU8988T	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.838370577898389	[447]	[729,722,823,816]	9	hSpCas9	negative selection	8778218
27820564	27820587	8	-	27260156	PATU8988T	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-1.450024395321727	[129]	[50,6,44,79]	-9	hSpCas9	negative selection	8778219
27820597	27820620	8	-	27260156	PATU8988T	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.31576684619850637	[453]	[265,790,241,135]	-5	hSpCas9	negative selection	8778220
27828162	27828185	8	+	27260156	T47D	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.6132330168590248	[203]	[275,468,313,386]	9	hSpCas9	negative selection	8835217
27828141	27828164	8	-	27260156	T47D	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.2230791847731255	[1159]	[1628,1609,1483,1584]	5	hSpCas9	negative selection	8835218
27811104	27811127	8	+	27260156	T47D	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.3210911283222976	[485]	[717,607,705,808]	6	hSpCas9	negative selection	8835219
27811006	27811029	8	+	27260156	T47D	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.6619535431246331	[447]	[826,690,853,945]	9	hSpCas9	negative selection	8899469
27820564	27820587	8	-	27260156	T47D	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.4756308447506983	[129]	[90,128,101,111]	-7	hSpCas9	negative selection	8899470
27820597	27820620	8	-	27260156	T47D	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.021376511129290943	[453]	[455,542,547,600]	0	hSpCas9	negative selection	8899471
27828162	27828185	8	+	27260156	SU8686	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.23206372256162489	[203]	[196,253,185,326]	4	hSpCas9	negative selection	8956468
27828141	27828164	8	-	27260156	SU8686	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.3989648320923729	[1159]	[1215,1307,1742,1920]	6	hSpCas9	negative selection	8956469
27811104	27811127	8	+	27260156	SU8686	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.2782748861549024	[485]	[580,603,517,633]	5	hSpCas9	negative selection	8956470
27811006	27811029	8	+	27260156	SU8686	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.5912863015896352	[447]	[613,598,640,863]	8	hSpCas9	negative selection	9020720
27820564	27820587	8	-	27260156	SU8686	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.6006160082722245	[129]	[64,51,74,166]	-7	hSpCas9	negative selection	9020721
27820597	27820620	8	-	27260156	SU8686	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.27794123962050565	[453]	[374,376,335,395]	-5	hSpCas9	negative selection	9020722
27828162	27828185	8	+	27260156	SKES1	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.046501781902191786	[203]	[174,175,239,234]	1	hSpCas9	negative selection	9077719
27828141	27828164	8	-	27260156	SKES1	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	-0.003649175723462461	[1159]	[1184,1214,1017,1194]	0	hSpCas9	negative selection	9077720
27811104	27811127	8	+	27260156	SKES1	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	-0.06340196438687125	[485]	[375,525,511,434]	-1	hSpCas9	negative selection	9077721
27811006	27811029	8	+	27260156	SKES1	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.4492793076884866	[447]	[738,597,691,440]	8	hSpCas9	negative selection	9141971
27820564	27820587	8	-	27260156	SKES1	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.6398183308191985	[129]	[66,88,128,48]	-8	hSpCas9	negative selection	9141972
27820597	27820620	8	-	27260156	SKES1	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.20932511892729153	[453]	[514,376,385,309]	-4	hSpCas9	negative selection	9141973
27828162	27828185	8	+	27260156	TOV112D	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.15042918240531478	[203]	[175,245,324,161]	3	hSpCas9	negative selection	9198970
27828141	27828164	8	-	27260156	TOV112D	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.19647151958915599	[1159]	[1354,1852,1045,1202]	4	hSpCas9	negative selection	9198971
27811104	27811127	8	+	27260156	TOV112D	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.46513799475754436	[485]	[660,741,556,740]	8	hSpCas9	negative selection	9198972
27811006	27811029	8	+	27260156	TOV112D	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.5906664700077344	[447]	[601,608,897,572]	9	hSpCas9	negative selection	9263222
27820564	27820587	8	-	27260156	TOV112D	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.8506654468419022	[129]	[85,184,24,22]	-9	hSpCas9	negative selection	9263223
27820597	27820620	8	-	27260156	TOV112D	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	0.1615364931460342	[453]	[485,554,638,366]	3	hSpCas9	negative selection	9263224
27828162	27828185	8	+	27260156	TC71	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.2280972488665457	[203]	[214,227,325,253]	5	hSpCas9	negative selection	9320221
27828141	27828164	8	-	27260156	TC71	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	0.24969639862001314	[1159]	[1508,1512,1363,1533]	6	hSpCas9	negative selection	9320222
27811104	27811127	8	+	27260156	TC71	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.08803221715327839	[485]	[570,613,537,487]	2	hSpCas9	negative selection	9320223
27811006	27811029	8	+	27260156	TC71	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.6746364039032997	[447]	[760,883,645,779]	9	hSpCas9	negative selection	9384473
27820564	27820587	8	-	27260156	TC71	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.5945314272135007	[129]	[64,49,65,195]	-9	hSpCas9	negative selection	9384474
27820597	27820620	8	-	27260156	TC71	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.11681126574034403	[453]	[460,471,394,469]	-3	hSpCas9	negative selection	9384475
27828162	27828185	8	+	27260156	TC32	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.04523557553878921	[203]	[169,131,325,148]	-1	hSpCas9	negative selection	9441472
27828141	27828164	8	-	27260156	TC32	viability	TCTCCGTTTATGCAGAAGCTTGG	PBK	ENSG00000168078	-0.017686894598214264	[1159]	[801,1078,1212,1209]	0	hSpCas9	negative selection	9441473
27811104	27811127	8	+	27260156	TC32	viability	GTGCCAATGTAACAAGCCTCAGG	PBK	ENSG00000168078	0.014844011211060368	[485]	[402,282,683,569]	0	hSpCas9	negative selection	9441474
27811006	27811029	8	+	27260156	TC32	viability	TCATCATTTCCCACAAAGTAAGG	PBK	ENSG00000168078	0.613689720579281	[447]	[533,492,909,723]	8	hSpCas9	negative selection	9505724
27820564	27820587	8	-	27260156	TC32	viability	CCACTGGATGAAAATATGACTGG	PBK	ENSG00000168078	-0.9266889722611673	[129]	[72,10,82,111]	-9	hSpCas9	negative selection	9505725
27820597	27820620	8	-	27260156	TC32	viability	ACAATTAAAATCTGTGATGTAGG	PBK	ENSG00000168078	-0.43427803237925244	[453]	[348,186,360,404]	-7	hSpCas9	negative selection	9505726
27811143	27811166	8	+	27869803	HPAFII	viability after 27 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	0.43181662305218127	[190]	[165,109,NaN]	3	hSpCas9	negative selection	9602354
27820580	27820603	8	-	27869803	HPAFII	viability after 27 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.37772351591813647	[178]	[118,124,NaN]	3	hSpCas9	negative selection	9602355
27811143	27811166	8	+	27869803	HPAFII	viability after 15 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	0.49722215216694593	[190]	[380,232,NaN]	6	hSpCas9	negative selection	9684803
27820580	27820603	8	-	27869803	HPAFII	viability after 15 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.4451950805590317	[178]	[301,236,NaN]	5	hSpCas9	negative selection	9684804
27811143	27811166	8	+	27869803	ASPC1	viability after 36 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.6141871527964542	[478]	[40,117,148]	-6	hSpCas9	negative selection	9767252
27820580	27820603	8	-	27869803	ASPC1	viability after 36 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.8665668527414927	[518]	[317,204,434]	8	hSpCas9	negative selection	9767253
27811143	27811166	8	+	27869803	PATU8988S	viability after 35 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.6703970404000488	[584]	[165,129,NaN]	-6	hSpCas9	negative selection	9849701
27820580	27820603	8	-	27869803	PATU8988S	viability after 35 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.6660226953817105	[407]	[130,75,NaN]	-6	hSpCas9	negative selection	9849702
27811143	27811166	8	+	27869803	PATU8988S	viability after 31 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	-0.7590802068913542	[584]	[88,199,NaN]	-7	hSpCas9	negative selection	9932150
27820580	27820603	8	-	27869803	PATU8988S	viability after 31 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	-0.20230595912171428	[407]	[147,132,NaN]	-2	hSpCas9	negative selection	9932151
27811143	27811166	8	+	27869803	HPAFII	viability after 35 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	0.6404563978193794	[190]	[193,101,NaN]	4	hSpCas9	negative selection	10014599
27820580	27820603	8	-	27869803	HPAFII	viability after 35 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.79354714937059	[178]	[181,128,NaN]	5	hSpCas9	negative selection	10014600
27811143	27811166	8	+	27869803	HPAFII	viability after 31 days	AGCAAGATGGTTATGAAGGCAGG	PBK	ENSG00000168078	0.6928918154206456	[190]	[212,129,NaN]	5	hSpCas9	negative selection	10097048
27820580	27820603	8	-	27869803	HPAFII	viability after 31 days	TGTAGGAGTCTCTCTACCACTGG	PBK	ENSG00000168078	0.2439401390277485	[178]	[106,131,NaN]	1	hSpCas9	negative selection	10097049
27811072	27811095	8	-	28162770	P31FUJ	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	0.6740883911941398	[239]	[449]	7	hSpCas9	negative selection	10207313
27822428	27822451	8	-	28162770	P31FUJ	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	0.34143388971371924	[44]	[66]	4	hSpCas9	negative selection	10207314
27833105	27833128	8	-	28162770	P31FUJ	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.2893857327807461	[259]	[249]	-3	hSpCas9	negative selection	10207315
27811094	27811117	8	-	28162770	P31FUJ	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.9590954276736907	[361]	[826]	9	hSpCas9	negative selection	10207316
27828143	27828166	8	+	28162770	P31FUJ	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	0.05319334986272636	[186]	[227]	0	hSpCas9	negative selection	10207317
27820564	27820587	8	+	28162770	P31FUJ	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.730298212774092	[197]	[385]	8	hSpCas9	negative selection	10207318
27828127	27828150	8	-	28162770	P31FUJ	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.40702223134129567	[601]	[937]	4	hSpCas9	negative selection	10207319
27822458	27822481	8	-	28162770	P31FUJ	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	0.5499374183889771	[303]	[522]	6	hSpCas9	negative selection	10207320
27828162	27828185	8	+	28162770	P31FUJ	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.831328133005337	[241]	[505]	8	hSpCas9	negative selection	10207321
27822445	27822468	8	+	28162770	P31FUJ	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.5775804103407938	[271]	[476]	6	hSpCas9	negative selection	10207322
27811072	27811095	8	-	28162770	TF1	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	NaN	[NaN]	[337]	1	hSpCas9	negative selection	10376679
27822428	27822451	8	-	28162770	TF1	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10376680
27833105	27833128	8	-	28162770	TF1	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	NaN	[NaN]	[341]	1	hSpCas9	negative selection	10376681
27811094	27811117	8	-	28162770	TF1	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	NaN	[NaN]	[382]	1	hSpCas9	negative selection	10376682
27828143	27828166	8	+	28162770	TF1	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	NaN	[NaN]	[106]	1	hSpCas9	negative selection	10376683
27820564	27820587	8	+	28162770	TF1	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	NaN	[NaN]	[226]	1	hSpCas9	negative selection	10376684
27828127	27828150	8	-	28162770	TF1	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	NaN	[NaN]	[431]	1	hSpCas9	negative selection	10376685
27822458	27822481	8	-	28162770	TF1	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	NaN	[NaN]	[330]	1	hSpCas9	negative selection	10376686
27828162	27828185	8	+	28162770	TF1	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	NaN	[NaN]	[367]	1	hSpCas9	negative selection	10376687
27822445	27822468	8	+	28162770	TF1	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	NaN	[NaN]	[472]	1	hSpCas9	negative selection	10376688
27811072	27811095	8	-	28162770	SKM1	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	0.5607180809841099	[78]	[205]	5	hSpCas9	negative selection	10546045
27822428	27822451	8	-	28162770	SKM1	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-0.8220016980220053	[7]	[7]	-6	hSpCas9	negative selection	10546046
27833105	27833128	8	-	28162770	SKM1	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.5027250302180303	[102]	[257]	5	hSpCas9	negative selection	10546047
27811094	27811117	8	-	28162770	SKM1	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.5161670378725678	[105]	[267]	5	hSpCas9	negative selection	10546048
27828143	27828166	8	+	28162770	SKM1	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	0.5488359973463031	[57]	[149]	5	hSpCas9	negative selection	10546049
27820564	27820587	8	+	28162770	SKM1	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.44282598963483916	[66]	[160]	4	hSpCas9	negative selection	10546050
27828127	27828150	8	-	28162770	SKM1	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.2469456556954861	[142]	[299]	2	hSpCas9	negative selection	10546051
27822458	27822481	8	-	28162770	SKM1	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	0.7564474957404761	[73]	[220]	7	hSpCas9	negative selection	10546052
27828162	27828185	8	+	28162770	SKM1	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.9129014296873081	[69]	[232]	8	hSpCas9	negative selection	10546053
27822445	27822468	8	+	28162770	SKM1	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.8478497002856635	[65]	[209]	7	hSpCas9	negative selection	10546054
27811072	27811095	8	-	28162770	SKM1	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	0.5607180809841099	[78]	[205]	5	hSpCas9	negative selection	10715411
27822428	27822451	8	-	28162770	SKM1	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-0.8220016980220053	[7]	[7]	-6	hSpCas9	negative selection	10715412
27833105	27833128	8	-	28162770	SKM1	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.5027250302180303	[102]	[257]	5	hSpCas9	negative selection	10715413
27811094	27811117	8	-	28162770	SKM1	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.5161670378725678	[105]	[267]	5	hSpCas9	negative selection	10715414
27828143	27828166	8	+	28162770	SKM1	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	0.5488359973463031	[57]	[149]	5	hSpCas9	negative selection	10715415
27820564	27820587	8	+	28162770	SKM1	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.44282598963483916	[66]	[160]	4	hSpCas9	negative selection	10715416
27828127	27828150	8	-	28162770	SKM1	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.2469456556954861	[142]	[299]	2	hSpCas9	negative selection	10715417
27822458	27822481	8	-	28162770	SKM1	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	0.7564474957404761	[73]	[220]	7	hSpCas9	negative selection	10715418
27828162	27828185	8	+	28162770	SKM1	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.9129014296873081	[69]	[232]	8	hSpCas9	negative selection	10715419
27822445	27822468	8	+	28162770	SKM1	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.8478497002856635	[65]	[209]	7	hSpCas9	negative selection	10715420
27811072	27811095	8	-	28162770	PL21	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	-0.2678467647384827	[295]	[106]	-2	hSpCas9	negative selection	10884777
27822428	27822451	8	-	28162770	PL21	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-1.3848228862318366	[23]	[3]	-7	hSpCas9	negative selection	10884778
27833105	27833128	8	-	28162770	PL21	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.40025336333556616	[288]	[165]	3	hSpCas9	negative selection	10884779
27811094	27811117	8	-	28162770	PL21	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.9226056389604111	[399]	[329]	7	hSpCas9	negative selection	10884780
27828143	27828166	8	+	28162770	PL21	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	0.37378770197434985	[171]	[96]	3	hSpCas9	negative selection	10884781
27820564	27820587	8	+	28162770	PL21	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.4406793825360276	[236]	[139]	4	hSpCas9	negative selection	10884782
27828127	27828150	8	-	28162770	PL21	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.4395227522584686	[409]	[241]	4	hSpCas9	negative selection	10884783
27822458	27822481	8	-	28162770	PL21	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	0.31912765070640703	[220]	[119]	3	hSpCas9	negative selection	10884784
27828162	27828185	8	+	28162770	PL21	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.7665661637730488	[234]	[173]	6	hSpCas9	negative selection	10884785
27822445	27822468	8	+	28162770	PL21	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.8119437274291175	[283]	[216]	7	hSpCas9	negative selection	10884786
27811072	27811095	8	-	28162770	P31FUJ	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	0.6740883911941398	[239]	[449]	7	hSpCas9	negative selection	11054143
27822428	27822451	8	-	28162770	P31FUJ	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	0.34143388971371924	[44]	[66]	4	hSpCas9	negative selection	11054144
27833105	27833128	8	-	28162770	P31FUJ	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.2893857327807461	[259]	[249]	-3	hSpCas9	negative selection	11054145
27811094	27811117	8	-	28162770	P31FUJ	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.9590954276736907	[361]	[826]	9	hSpCas9	negative selection	11054146
27828143	27828166	8	+	28162770	P31FUJ	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	0.05319334986272636	[186]	[227]	0	hSpCas9	negative selection	11054147
27820564	27820587	8	+	28162770	P31FUJ	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.730298212774092	[197]	[385]	8	hSpCas9	negative selection	11054148
27828127	27828150	8	-	28162770	P31FUJ	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.40702223134129567	[601]	[937]	4	hSpCas9	negative selection	11054149
27822458	27822481	8	-	28162770	P31FUJ	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	0.5499374183889771	[303]	[522]	6	hSpCas9	negative selection	11054150
27828162	27828185	8	+	28162770	P31FUJ	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.831328133005337	[241]	[505]	8	hSpCas9	negative selection	11054151
27822445	27822468	8	+	28162770	P31FUJ	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.5775804103407938	[271]	[476]	6	hSpCas9	negative selection	11054152
27811072	27811095	8	-	28162770	OCIAML5	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	0.5525543124695085	[138]	[367]	5	hSpCas9	negative selection	11223509
27822428	27822451	8	-	28162770	OCIAML5	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-0.93452873105597	[35]	[33]	-5	hSpCas9	negative selection	11223510
27833105	27833128	8	-	28162770	OCIAML5	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.2245121934183728	[177]	[274]	-2	hSpCas9	negative selection	11223511
27811094	27811117	8	-	28162770	OCIAML5	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.6411797607655438	[183]	[517]	5	hSpCas9	negative selection	11223512
27828143	27828166	8	+	28162770	OCIAML5	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	0.08081923327746612	[131]	[251]	0	hSpCas9	negative selection	11223513
27820564	27820587	8	+	28162770	OCIAML5	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.30676072169498475	[115]	[258]	2	hSpCas9	negative selection	11223514
27828127	27828150	8	-	28162770	OCIAML5	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.8515404263557784	[244]	[797]	7	hSpCas9	negative selection	11223515
27822458	27822481	8	-	28162770	OCIAML5	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	0.4938247673740809	[202]	[515]	4	hSpCas9	negative selection	11223516
27828162	27828185	8	+	28162770	OCIAML5	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.6997766552752946	[234]	[688]	6	hSpCas9	negative selection	11223517
27822445	27822468	8	+	28162770	OCIAML5	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.9749996778213521	[134]	[478]	8	hSpCas9	negative selection	11223518
27811072	27811095	8	-	28162770	EOL1	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	0.2391453697283501	[512]	[318]	2	hSpCas9	negative selection	11392875
27822428	27822451	8	-	28162770	EOL1	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-2.1909294458494015	[51]	[5]	-8	hSpCas9	negative selection	11392876
27833105	27833128	8	-	28162770	EOL1	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.4137862126907955	[539]	[378]	4	hSpCas9	negative selection	11392877
27811094	27811117	8	-	28162770	EOL1	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.27142847690326977	[790]	[502]	2	hSpCas9	negative selection	11392878
27828143	27828166	8	+	28162770	EOL1	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.998830946826553	[329]	[86]	-6	hSpCas9	negative selection	11392879
27820564	27820587	8	+	28162770	EOL1	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.08949717772213894	[354]	[198]	0	hSpCas9	negative selection	11392880
27828127	27828150	8	-	28162770	EOL1	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.06412222057840256	[442]	[243]	0	hSpCas9	negative selection	11392881
27822458	27822481	8	-	28162770	EOL1	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	-0.062031712667143926	[320]	[161]	0	hSpCas9	negative selection	11392882
27828162	27828185	8	+	28162770	EOL1	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.06913339345310146	[350]	[193]	0	hSpCas9	negative selection	11392883
27822445	27822468	8	+	28162770	EOL1	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.6598445453761222	[345]	[287]	6	hSpCas9	negative selection	11392884
27811072	27811095	8	-	28162770	MOLM13	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	0.36862775017150207	[375]	[350]	2	hSpCas9	negative selection	11562241
27822428	27822451	8	-	28162770	MOLM13	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-1.0060418067878332	[24]	[8]	-5	hSpCas9	negative selection	11562242
27833105	27833128	8	-	28162770	MOLM13	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.8062244701697048	[548]	[226]	-4	hSpCas9	negative selection	11562243
27811094	27811117	8	-	28162770	MOLM13	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.5388111674751962	[515]	[541]	4	hSpCas9	negative selection	11562244
27828143	27828166	8	+	28162770	MOLM13	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.6587440569864385	[237]	[108]	-4	hSpCas9	negative selection	11562245
27820564	27820587	8	+	28162770	MOLM13	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.9485937984724174	[305]	[426]	7	hSpCas9	negative selection	11562246
27828127	27828150	8	-	28162770	MOLM13	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	-0.6355402081108268	[635]	[295]	-4	hSpCas9	negative selection	11562247
27822458	27822481	8	-	28162770	MOLM13	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	-0.9069182729457321	[388]	[149]	-5	hSpCas9	negative selection	11562248
27828162	27828185	8	+	28162770	MOLM13	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.05022162622106302	[365]	[273]	0	hSpCas9	negative selection	11562249
27822445	27822468	8	+	28162770	MOLM13	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	1.0419085045791534	[396]	[590]	7	hSpCas9	negative selection	11562250
27811072	27811095	8	-	28162770	HEL	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	0.6511756691489967	[340]	[342]	5	hSpCas9	negative selection	11731607
27822428	27822451	8	-	28162770	HEL	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	0.9322454491953418	[26]	[32]	7	hSpCas9	negative selection	11731608
27833105	27833128	8	-	28162770	HEL	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	0.6625020868217869	[434]	[440]	5	hSpCas9	negative selection	11731609
27811094	27811117	8	-	28162770	HEL	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.8466839423751725	[460]	[530]	7	hSpCas9	negative selection	11731610
27828143	27828166	8	+	28162770	HEL	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	0.029761955109604138	[259]	[169]	0	hSpCas9	negative selection	11731611
27820564	27820587	8	+	28162770	HEL	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.3521068676025331	[284]	[232]	3	hSpCas9	negative selection	11731612
27828127	27828150	8	-	28162770	HEL	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.27484711234745385	[581]	[450]	2	hSpCas9	negative selection	11731613
27822458	27822481	8	-	28162770	HEL	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	0.4347975669614496	[297]	[257]	3	hSpCas9	negative selection	11731614
27828162	27828185	8	+	28162770	HEL	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.7802423557502922	[309]	[340]	6	hSpCas9	negative selection	11731615
27822445	27822468	8	+	28162770	HEL	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.5525410230287788	[263]	[247]	5	hSpCas9	negative selection	11731616
27811072	27811095	8	-	28162770	MV411	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	-0.4169594174327858	[251]	[158]	-3	hSpCas9	negative selection	11900973
27822428	27822451	8	-	28162770	MV411	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	0.8754687733958177	[10]	[16]	7	hSpCas9	negative selection	11900974
27833105	27833128	8	-	28162770	MV411	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.12614552132435092	[262]	[202]	-1	hSpCas9	negative selection	11900975
27811094	27811117	8	-	28162770	MV411	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.15930664050411014	[404]	[380]	1	hSpCas9	negative selection	11900976
27828143	27828166	8	+	28162770	MV411	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.5688504960448367	[161]	[91]	-4	hSpCas9	negative selection	11900977
27820564	27820587	8	+	28162770	MV411	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.36773178450048716	[206]	[224]	3	hSpCas9	negative selection	11900978
27828127	27828150	8	-	28162770	MV411	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	-0.281490915024053	[403]	[279]	-2	hSpCas9	negative selection	11900979
27822458	27822481	8	-	28162770	MV411	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	-0.388508878657186	[215]	[138]	-3	hSpCas9	negative selection	11900980
27828162	27828185	8	+	28162770	MV411	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.2795497359365282	[310]	[317]	2	hSpCas9	negative selection	11900981
27822445	27822468	8	+	28162770	MV411	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.3369891357610677	[202]	[215]	3	hSpCas9	negative selection	11900982
27811072	27811095	8	-	28162770	MONOMAC1	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	0.28628539178576473	[195]	[273]	3	hSpCas9	negative selection	12070339
27822428	27822451	8	-	28162770	MONOMAC1	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-1.1145746868675808	[16]	[8]	-7	hSpCas9	negative selection	12070340
27833105	27833128	8	-	28162770	MONOMAC1	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.2650136408755607	[238]	[227]	-2	hSpCas9	negative selection	12070341
27811094	27811117	8	-	28162770	MONOMAC1	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.7965368837810135	[224]	[447]	7	hSpCas9	negative selection	12070342
27828143	27828166	8	+	28162770	MONOMAC1	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.2112507062792544	[101]	[100]	-2	hSpCas9	negative selection	12070343
27820564	27820587	8	+	28162770	MONOMAC1	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.38401060365821943	[122]	[183]	4	hSpCas9	negative selection	12070344
27828127	27828150	8	-	28162770	MONOMAC1	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	0.634321117381607	[280]	[499]	6	hSpCas9	negative selection	12070345
27822458	27822481	8	-	28162770	MONOMAC1	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	0.1287333141222028	[149]	[187]	1	hSpCas9	negative selection	12070346
27828162	27828185	8	+	28162770	MONOMAC1	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.35996064512562387	[190]	[280]	3	hSpCas9	negative selection	12070347
27822445	27822468	8	+	28162770	MONOMAC1	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	0.7165484011229729	[128]	[242]	6	hSpCas9	negative selection	12070348
27811072	27811095	8	-	28162770	OCIAML2	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	-0.1136952805268856	[56]	[291]	-1	hSpCas9	negative selection	12239705
27822428	27822451	8	-	28162770	OCIAML2	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	-0.5637392296336428	[3]	[14]	-4	hSpCas9	negative selection	12239706
27833105	27833128	8	-	28162770	OCIAML2	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.046340012725121116	[67]	[364]	0	hSpCas9	negative selection	12239707
27811094	27811117	8	-	28162770	OCIAML2	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.5764940868718645	[63]	[528]	5	hSpCas9	negative selection	12239708
27828143	27828166	8	+	28162770	OCIAML2	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	0.5056541057840314	[22]	[180]	5	hSpCas9	negative selection	12239709
27820564	27820587	8	+	28162770	OCIAML2	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.5187229305583302	[33]	[269]	5	hSpCas9	negative selection	12239710
27828127	27828150	8	-	28162770	OCIAML2	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	-0.042295503349859764	[80]	[435]	0	hSpCas9	negative selection	12239711
27822458	27822481	8	-	28162770	OCIAML2	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	0.07443994835548218	[54]	[320]	0	hSpCas9	negative selection	12239712
27828162	27828185	8	+	28162770	OCIAML2	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	0.1635761944988443	[47]	[297]	1	hSpCas9	negative selection	12239713
27822445	27822468	8	+	28162770	OCIAML2	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	-0.3413468082971949	[47]	[209]	-3	hSpCas9	negative selection	12239714
27811072	27811095	8	-	28162770	OCIAML3	viability	GAAACCCAAAGAAGCTGTGGAGG	PBK	ENSG00000168078	-0.1345760216868659	[83]	[230]	-1	hSpCas9	negative selection	12409071
27822428	27822451	8	-	28162770	OCIAML3	viability	TGTCTTGCTATGGAATATGGAGG	PBK	ENSG00000168078	0.9084927002050196	[2]	[16]	7	hSpCas9	negative selection	12409072
27833105	27833128	8	-	28162770	OCIAML3	viability	GAGTGGCTTTCACAATGGAAGGG	PBK	ENSG00000168078	-0.897684030655303	[107]	[174]	-6	hSpCas9	negative selection	12409073
27811094	27811117	8	-	28162770	OCIAML3	viability	GTTACATTGGCACAGAGCCATGG	PBK	ENSG00000168078	0.6790108540822526	[101]	[492]	6	hSpCas9	negative selection	12409074
27828143	27828166	8	+	28162770	OCIAML3	viability	AAGCTTCTGCATAAACGGAGAGG	PBK	ENSG00000168078	-0.43003190521303725	[53]	[120]	-3	hSpCas9	negative selection	12409075
27820564	27820587	8	+	28162770	OCIAML3	viability	CCAGTCATATTTTCATCCAGTGG	PBK	ENSG00000168078	0.6602336470516246	[47]	[228]	6	hSpCas9	negative selection	12409076
27828127	27828150	8	-	28162770	OCIAML3	viability	GAAGCTTGGCTTTGGTACTGGGG	PBK	ENSG00000168078	-0.1471614028146433	[156]	[427]	-1	hSpCas9	negative selection	12409077
27822458	27822481	8	-	28162770	OCIAML3	viability	GCTTTTACTGAAGCCAATGATGG	PBK	ENSG00000168078	0.0203386671780873	[80]	[247]	0	hSpCas9	negative selection	12409078
27828162	27828185	8	+	28162770	OCIAML3	viability	GAGGCCGGGATATTTATAGTTGG	PBK	ENSG00000168078	-0.7527053863432214	[71]	[128]	-5	hSpCas9	negative selection	12409079
27822445	27822468	8	+	28162770	OCIAML3	viability	AAGACACAGACTGCCATCATTGG	PBK	ENSG00000168078	-0.20406112200814985	[57]	[151]	-2	hSpCas9	negative selection	12409080