| 271725 | 271748 | 5 | - | 26472758 | Jiyoye | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -0.7835081801032363 | [209] | [91] | -5 | hSpCas9 | negative selection | 117817 | 271800 | 271823 | 5 | + | 26472758 | Jiyoye | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.8980395079798278 | [453] | [637] | 6 | hSpCas9 | negative selection | 117819 | 271725 | 271748 | 5 | - | 26472758 | KBM7 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -0.829695307019225 | [823,687] | [139,251] | -6 | hSpCas9 | negative selection | 308935 | 271800 | 271823 | 5 | + | 26472758 | KBM7 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.3759428226533359 | [2618,2235] | [1751,1229] | 4 | hSpCas9 | negative selection | 308937 | 271725 | 271748 | 5 | - | 26472758 | Raji | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -0.6100292613712062 | [341] | [51] | -5 | hSpCas9 | negative selection | 500053 | 271800 | 271823 | 5 | + | 26472758 | Raji | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.18912668481513584 | [891] | [235] | 1 | hSpCas9 | negative selection | 500055 | 271725 | 271748 | 5 | - | 26472758 | K562 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -0.8033344037819212 | [644] | [311] | -5 | hSpCas9 | negative selection | 691171 | 271800 | 271823 | 5 | + | 26472758 | K562 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.3555777884926936 | [1672] | [1806] | 2 | hSpCas9 | negative selection | 691173 | 271718 | 271741 | 5 | - | 24336569 | HL60 | viability | CGGTAAGAGTAGGCGGCCATGGG | PDCD6 | ENSG00000249915 | 0.3115470923199486 | [494] | [1299] | 3 | hSpCas9 | negative selection | 2283223 | 271755 | 271778 | 5 | - | 24336569 | HL60 | viability | GCCTGCAGCAGGCCCAGGGCCGG | PDCD6 | ENSG00000249915 | -0.6580492528121145 | [600] | [805] | -5 | hSpCas9 | negative selection | 2283224 | 271718 | 271741 | 5 | - | 24336569 | KBM7 | viability | CGGTAAGAGTAGGCGGCCATGGG | PDCD6 | ENSG00000249915 | -0.5446466145090474 | [729] | [1364] | -4 | hSpCas9 | negative selection | 2350400 | 271755 | 271778 | 5 | - | 24336569 | KBM7 | viability | GCCTGCAGCAGGCCCAGGGCCGG | PDCD6 | ENSG00000249915 | -0.12224047349886821 | [337] | [846] | -1 | hSpCas9 | negative selection | 2350401 | 304045 | 304068 | 5 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | AGTGGTTTTCTAGACACTCCAGG | PDCD6 | ENSG00000249915 | 1.3952183349278156 | [1101,425] | [112,791] | 5 | dCas9-VP64 | positive selection | 2452282 | 304027 | 304050 | 5 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ATGGCAGCCGACACGTCACCTGG | PDCD6 | ENSG00000249915 | 0.13112022966096193 | [532,251] | [56,133] | 0 | dCas9-VP64 | positive selection | 2452284 | 303977 | 304000 | 5 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGCAGGGTGTGAACCCACCAGG | PDCD6 | ENSG00000249915 | 6.206546620039431 | [117,75] | [88,3190] | 9 | dCas9-VP64 | positive selection | 2452285 | 290522 | 290545 | 5 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CTACCACCAACCCTCCAACATGG | PDCD6 | ENSG00000249915 | 2.2176916459102958 | [147,55] | [193,6] | 7 | dCas9-VP64 | positive selection | 2471187 | 304045 | 304068 | 5 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | AGTGGTTTTCTAGACACTCCAGG | PDCD6 | ENSG00000249915 | 0.09498543722859931 | [247,118] | [69,58] | 0 | dCas9-VP64 | positive selection | 2547537 | 304027 | 304050 | 5 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ATGGCAGCCGACACGTCACCTGG | PDCD6 | ENSG00000249915 | 1.166837590289494 | [275,243] | [80,292] | 7 | dCas9-VP64 | positive selection | 2547539 | 303977 | 304000 | 5 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGCAGGGTGTGAACCCACCAGG | PDCD6 | ENSG00000249915 | 5.615364120530151 | [50,40] | [26,1422] | 9 | dCas9-VP64 | positive selection | 2547540 | 290522 | 290545 | 5 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CTACCACCAACCCTCCAACATGG | PDCD6 | ENSG00000249915 | -1.2614224522991961 | [121,208] | [28,14] | -9 | dCas9-VP64 | positive selection | 2566442 | 271801 | 271824 | 5 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | ACCTCTGGAAAACGTTCCACAGG | PDCD6 | ENSG00000249915 | 0.18536394465660977 | [3,2] | [2,3] | 4 | hSpCas9 | positive selection | 3010304 | 271759 | 271782 | 5 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CCGCGCCTGCAGCAGGCCCAGGG | PDCD6 | ENSG00000249915 | -0.9307105648950681 | [3,3] | [1,0] | -9 | hSpCas9 | positive selection | 3010305 | 271725 | 271748 | 5 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCCGCCTACTCTTACCGCCCCGG | PDCD6 | ENSG00000249915 | 0.2725691382893123 | [3,3] | [2,4] | 6 | hSpCas9 | positive selection | 3010306 | 271725 | 271748 | 5 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | 0.15566585225277535 | [3,3] | [2,4] | 3 | hSpCas9 | positive selection | 3010307 | 271801 | 271824 | 5 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | ACCTCTGGAAAACGTTCCACAGG | PDCD6 | ENSG00000249915 | -0.6293856118996637 | [3,3] | [1,1] | -8 | hSpCas9 | positive selection | 3078162 | 271759 | 271782 | 5 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CCGCGCCTGCAGCAGGCCCAGGG | PDCD6 | ENSG00000249915 | -0.07227193025595069 | [3,3] | [3,1] | -1 | hSpCas9 | positive selection | 3078163 | 271725 | 271748 | 5 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCCGCCTACTCTTACCGCCCCGG | PDCD6 | ENSG00000249915 | 0.14597797209726454 | [3,3] | [3,1] | 2 | hSpCas9 | positive selection | 3078164 | 271725 | 271748 | 5 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -0.6595232868143481 | [3,3] | [2,0] | -8 | hSpCas9 | positive selection | 3078165 | 272746 | 272769 | 5 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.2425196756373702 | [180,180] | [0,0] | -1 | hSpCas9 | positive selection | 3385067 | 272704 | 272727 | 5 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | 1.529405756882636 | [52,52] | [0,0] | 6 | hSpCas9 | positive selection | 3385068 | 271801 | 271824 | 5 | - | 26780180 | HT29 | viability (Avana library 4 designs) | ACCTCTGGAAAACGTTCCACAGG | PDCD6 | ENSG00000249915 | 1.00168760499473 | [] | [] | 4 | hSpCas9 | negative selection | 3448355 | 271759 | 271782 | 5 | - | 26780180 | HT29 | viability (Avana library 4 designs) | CCGCGCCTGCAGCAGGCCCAGGG | PDCD6 | ENSG00000249915 | 2.9597833892222 | [] | [] | 8 | hSpCas9 | negative selection | 3448356 | 271724 | 271747 | 5 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GCCGCCTACTCTTACCGCCCCGG | PDCD6 | ENSG00000249915 | 2.86456846733868 | [] | [] | 8 | hSpCas9 | negative selection | 3448357 | 271725 | 271748 | 5 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | 2.80193185444493 | [] | [] | 8 | hSpCas9 | negative selection | 3448358 | 271725 | 271748 | 5 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -0.208087414893195 | [] | [] | 0 | hSpCas9 | negative selection | 3542599 | 271759 | 271782 | 5 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCGCGCCTGCAGCAGGCCCAGGG | PDCD6 | ENSG00000249915 | -1.06448940766745 | [] | [] | -1 | hSpCas9 | negative selection | 3542600 | 271801 | 271824 | 5 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ACCTCTGGAAAACGTTCCACAGG | PDCD6 | ENSG00000249915 | -6.54282601716816 | [] | [] | -6 | hSpCas9 | negative selection | 3542601 | 271724 | 271747 | 5 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCCGCCTACTCTTACCGCCCCGG | PDCD6 | ENSG00000249915 | -5.99792928233494 | [] | [] | -6 | hSpCas9 | negative selection | 3542602 | 271732 | 271755 | 5 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CTCTTACCGCCCCGGCCCTGGGG | PDCD6 | ENSG00000249915 | 3.17497301175137 | [] | [] | 5 | hSpCas9 | negative selection | 3542603 | 271747 | 271770 | 5 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CAGGCCCAGGGCCGGCCCCAGGG | PDCD6 | ENSG00000249915 | 8.15278044756003 | [] | [] | 9 | hSpCas9 | negative selection | 3542604 | 271725 | 271748 | 5 | - | 26780180 | A375 | viability (Avana lentiGuide) | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | 5.45377976513886 | [] | [] | 5 | hSpCas9 | negative selection | 3651258 | 271759 | 271782 | 5 | - | 26780180 | A375 | viability (Avana lentiGuide) | CCGCGCCTGCAGCAGGCCCAGGG | PDCD6 | ENSG00000249915 | 20.9168777873085 | [] | [] | 8 | hSpCas9 | negative selection | 3651259 | 271801 | 271824 | 5 | - | 26780180 | A375 | viability (Avana lentiGuide) | ACCTCTGGAAAACGTTCCACAGG | PDCD6 | ENSG00000249915 | 7.44086330711068 | [] | [] | 6 | hSpCas9 | negative selection | 3651260 | 271724 | 271747 | 5 | + | 26780180 | A375 | viability (Avana lentiGuide) | GCCGCCTACTCTTACCGCCCCGG | PDCD6 | ENSG00000249915 | 11.2947157711121 | [] | [] | 7 | hSpCas9 | negative selection | 3651261 | 271732 | 271755 | 5 | + | 26780180 | A375 | viability (Avana lentiGuide) | CTCTTACCGCCCCGGCCCTGGGG | PDCD6 | ENSG00000249915 | -0.257883582443083 | [] | [] | 0 | hSpCas9 | negative selection | 3651262 | 271747 | 271770 | 5 | - | 26780180 | A375 | viability (Avana lentiGuide) | CAGGCCCAGGGCCGGCCCCAGGG | PDCD6 | ENSG00000249915 | -3.82685073453121 | [] | [] | -6 | hSpCas9 | negative selection | 3651263 | 271725 | 271748 | 5 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -0.10535202786458536 | [5] | [5,4] | -2 | hSpCas9 | positive selection | 3759917 | 271759 | 271782 | 5 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCGCGCCTGCAGCAGGCCCAGGG | PDCD6 | ENSG00000249915 | 0.00315040629030495 | [5] | [5,4] | 0 | hSpCas9 | positive selection | 3759918 | 271801 | 271824 | 5 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ACCTCTGGAAAACGTTCCACAGG | PDCD6 | ENSG00000249915 | -0.5414036474059261 | [4] | [2,2] | -7 | hSpCas9 | positive selection | 3759919 | 271724 | 271747 | 5 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCCGCCTACTCTTACCGCCCCGG | PDCD6 | ENSG00000249915 | -0.3111139534064912 | [5] | [4,3] | -5 | hSpCas9 | positive selection | 3759920 | 271732 | 271755 | 5 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CTCTTACCGCCCCGGCCCTGGGG | PDCD6 | ENSG00000249915 | 0.263163421614935 | [5] | [7,6] | 7 | hSpCas9 | positive selection | 3759921 | 271747 | 271770 | 5 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CAGGCCCAGGGCCGGCCCCAGGG | PDCD6 | ENSG00000249915 | 0.38322423697531516 | [5] | [6,6] | 9 | hSpCas9 | positive selection | 3759922 | 271725 | 271748 | 5 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -0.35876698461211065 | [5] | [2,4] | -5 | hSpCas9 | positive selection | 3868524 | 271759 | 271782 | 5 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCGCGCCTGCAGCAGGCCCAGGG | PDCD6 | ENSG00000249915 | -1.8934376873311562 | [6] | [0,0] | -9 | hSpCas9 | positive selection | 3868525 | 271801 | 271824 | 5 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ACCTCTGGAAAACGTTCCACAGG | PDCD6 | ENSG00000249915 | -0.5982962247381449 | [4] | [3,0] | -6 | hSpCas9 | positive selection | 3868526 | 271724 | 271747 | 5 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCCGCCTACTCTTACCGCCCCGG | PDCD6 | ENSG00000249915 | -0.2771434906598577 | [6] | [4,3] | -4 | hSpCas9 | positive selection | 3868527 | 271732 | 271755 | 5 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CTCTTACCGCCCCGGCCCTGGGG | PDCD6 | ENSG00000249915 | 0.2776916777730196 | [6] | [7,6] | 7 | hSpCas9 | positive selection | 3868528 | 271747 | 271770 | 5 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CAGGCCCAGGGCCGGCCCCAGGG | PDCD6 | ENSG00000249915 | 0.28169393598204495 | [5] | [6,5] | 7 | hSpCas9 | positive selection | 3868529 | 272746 | 272769 | 5 | - | 26780180 | A375 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | 1.55370263586665 | [] | [] | 8 | hSpCas9 | negative selection | 3979300 | 272704 | 272727 | 5 | + | 26780180 | A375 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | 1.45706582865322 | [] | [] | 8 | hSpCas9 | negative selection | 3979301 | 272746 | 272769 | 5 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | 2.14439302015461 | [] | [] | 9 | hSpCas9 | negative selection | 4087266 | 272704 | 272727 | 5 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | 1.17554459009697 | [] | [] | 5 | hSpCas9 | negative selection | 4087267 | 272746 | 272769 | 5 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.6098463163692969 | [3] | [2,0] | -8 | hSpCas9 | positive selection | 4353641 | 272704 | 272727 | 5 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.280359324231672 | [1] | [0,1] | -5 | hSpCas9 | positive selection | 4353642 | 271801 | 271823 | 5 | + | 27760321 | OCIAML3 | viability | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -0.4199045477978138 | [412,286] | [170,242] | -4 | hSpCas9 | negative selection | 4426448 | 271816 | 271838 | 5 | - | 27760321 | OCIAML3 | viability | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -0.7711747012230925 | [741,759] | [296,408] | -6 | hSpCas9 | negative selection | 4426449 | 272705 | 272727 | 5 | + | 27760321 | OCIAML3 | viability | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -3.4710052556090902 | [18,9] | [0,0] | -9 | hSpCas9 | negative selection | 4426450 | 272746 | 272768 | 5 | - | 27760321 | OCIAML3 | viability | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.245852048789979 | [465,406] | [150,133] | -8 | hSpCas9 | negative selection | 4426451 | 271801 | 271823 | 5 | + | 27760321 | OCIAML2 | viability | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -0.433720487082254 | [412,286] | [217,192] | -5 | hSpCas9 | negative selection | 4509911 | 271816 | 271838 | 5 | - | 27760321 | OCIAML2 | viability | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -0.2656413241694382 | [741,759] | [431,606] | -3 | hSpCas9 | negative selection | 4509912 | 272705 | 272727 | 5 | + | 27760321 | OCIAML2 | viability | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -1.0478562070107484 | [18,9] | [8,0] | -7 | hSpCas9 | negative selection | 4509913 | 272746 | 272768 | 5 | - | 27760321 | OCIAML2 | viability | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.0887066839026787 | [465,406] | [153,180] | -7 | hSpCas9 | negative selection | 4509914 | 271801 | 271823 | 5 | + | 27760321 | MV411 | viability | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -1.4846184330310817 | [412,286] | [63,107] | -7 | hSpCas9 | negative selection | 4593374 | 271816 | 271838 | 5 | - | 27760321 | MV411 | viability | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -0.013001683588398372 | [741,759] | [535,428] | 0 | hSpCas9 | negative selection | 4593375 | 272705 | 272727 | 5 | + | 27760321 | MV411 | viability | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -3.2259266866944083 | [18,9] | [0,0] | -9 | hSpCas9 | negative selection | 4593376 | 272746 | 272768 | 5 | - | 27760321 | MV411 | viability | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.0156439076088712 | [465,406] | [78,236] | -6 | hSpCas9 | negative selection | 4593377 | 271801 | 271823 | 5 | + | 27760321 | HL60 | viability | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -0.3957708329833584 | [412,286] | [158,273] | -4 | hSpCas9 | negative selection | 4676837 | 271816 | 271838 | 5 | - | 27760321 | HL60 | viability | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -0.06427628315519318 | [741,759] | [613,562] | 0 | hSpCas9 | negative selection | 4676838 | 272705 | 272727 | 5 | + | 27760321 | HL60 | viability | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | 0.4244828389566644 | [18,9] | [16,13] | 5 | hSpCas9 | negative selection | 4676839 | 272746 | 272768 | 5 | - | 27760321 | HL60 | viability | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.4758450231547581 | [465,406] | [265,244] | -5 | hSpCas9 | negative selection | 4676840 | 271801 | 271823 | 5 | + | 27760321 | HT1080 | viability | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -1.1673824213479644 | [286,223] | [51,37] | -4 | hSpCas9 | negative selection | 4760300 | 271816 | 271838 | 5 | - | 27760321 | HT1080 | viability | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -1.7749779151564788 | [759,592] | [104,49] | -6 | hSpCas9 | negative selection | 4760301 | 272705 | 272727 | 5 | + | 27760321 | HT1080 | viability | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -1.8443172389209588 | [9,7] | [0,0] | -6 | hSpCas9 | negative selection | 4760302 | 272746 | 272768 | 5 | - | 27760321 | HT1080 | viability | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.9822987157343566 | [406,317] | [5,69] | -6 | hSpCas9 | negative selection | 4760303 | 271801 | 271823 | 5 | + | 27760321 | HT29 | viability after 7 days | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.8284843123980444 | [286,223] | [590,565,592] | 9 | hSpCas9 | negative selection | 4843763 | 271816 | 271838 | 5 | - | 27760321 | HT29 | viability after 7 days | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -0.22088314904884032 | [759,592] | [1080,631,577] | -3 | hSpCas9 | negative selection | 4843764 | 272705 | 272727 | 5 | + | 27760321 | HT29 | viability after 7 days | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | 0.7100097042031939 | [9,7] | [17,28,9] | 9 | hSpCas9 | negative selection | 4843765 | 272746 | 272768 | 5 | - | 27760321 | HT29 | viability after 7 days | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.821298400187095 | [406,317] | [415,206,191] | -8 | hSpCas9 | negative selection | 4843766 | 271801 | 271823 | 5 | + | 27760321 | HT29 | viability after 25 days | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.44699535954156844 | [286,223] | [347,309,554] | 5 | hSpCas9 | negative selection | 4927226 | 271816 | 271838 | 5 | - | 27760321 | HT29 | viability after 25 days | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | 0.006130708263853535 | [759,592] | [956,562,798] | 0 | hSpCas9 | negative selection | 4927227 | 272705 | 272727 | 5 | + | 27760321 | HT29 | viability after 25 days | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.1009911094690974 | [9,7] | [17,2,6] | -1 | hSpCas9 | negative selection | 4927228 | 272746 | 272768 | 5 | - | 27760321 | HT29 | viability after 25 days | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.2878822402482974 | [406,317] | [225,145,128] | -7 | hSpCas9 | negative selection | 4927229 | 271801 | 271823 | 5 | + | 27760321 | HT29 | viability after 22 days | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.575249129448778 | [286,223] | [336,338,648] | 6 | hSpCas9 | negative selection | 5010689 | 271816 | 271838 | 5 | - | 27760321 | HT29 | viability after 22 days | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -0.29707455448565123 | [759,592] | [703,430,773] | -3 | hSpCas9 | negative selection | 5010690 | 272705 | 272727 | 5 | + | 27760321 | HT29 | viability after 22 days | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | 1.1070577777576869 | [9,7] | [8,4,53] | 9 | hSpCas9 | negative selection | 5010691 | 272746 | 272768 | 5 | - | 27760321 | HT29 | viability after 22 days | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.4397708762048333 | [406,317] | [178,212,69] | -7 | hSpCas9 | negative selection | 5010692 | 271801 | 271823 | 5 | + | 27760321 | HT29 | viability after 19 days | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.412513900713055 | [286,223] | [338,317,499] | 4 | hSpCas9 | negative selection | 5094152 | 271816 | 271838 | 5 | - | 27760321 | HT29 | viability after 19 days | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -0.10334914822779973 | [759,592] | [800,658,708] | -1 | hSpCas9 | negative selection | 5094153 | 272705 | 272727 | 5 | + | 27760321 | HT29 | viability after 19 days | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | 2.814664528397878 | [9,7] | [14,136,59] | 9 | hSpCas9 | negative selection | 5094154 | 272746 | 272768 | 5 | - | 27760321 | HT29 | viability after 19 days | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.9167944224974802 | [406,317] | [220,90,31] | -8 | hSpCas9 | negative selection | 5094155 | 271801 | 271823 | 5 | + | 27760321 | HT29 | viability after 16 days | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -0.1366677063845641 | [286,223] | [241,271,263] | -1 | hSpCas9 | negative selection | 5177615 | 271816 | 271838 | 5 | - | 27760321 | HT29 | viability after 16 days | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -0.10471019567204087 | [759,592] | [966,487,686] | -1 | hSpCas9 | negative selection | 5177616 | 272705 | 272727 | 5 | + | 27760321 | HT29 | viability after 16 days | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | 1.1682752746672467 | [9,7] | [33,24,9] | 9 | hSpCas9 | negative selection | 5177617 | 272746 | 272768 | 5 | - | 27760321 | HT29 | viability after 16 days | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.6240178349082635 | [406,317] | [260,91,54] | -8 | hSpCas9 | negative selection | 5177618 | 271801 | 271823 | 5 | + | 27760321 | HT29 | viability after 13 days | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.6830852840563939 | [286,223] | [324,405,683] | 8 | hSpCas9 | negative selection | 5261078 | 271816 | 271838 | 5 | - | 27760321 | HT29 | viability after 13 days | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -0.0009720600547844516 | [759,592] | [986,679,690] | 0 | hSpCas9 | negative selection | 5261079 | 272705 | 272727 | 5 | + | 27760321 | HT29 | viability after 13 days | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.9458776775543516 | [9,7] | [4,0,9] | -7 | hSpCas9 | negative selection | 5261080 | 272746 | 272768 | 5 | - | 27760321 | HT29 | viability after 13 days | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.127187968927104 | [406,317] | [133,255,187] | -7 | hSpCas9 | negative selection | 5261081 | 271801 | 271823 | 5 | + | 27760321 | HT29 | viability after 10 days | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.8675307014154491 | [286,223] | [431,768,550] | 9 | hSpCas9 | negative selection | 5344541 | 271816 | 271838 | 5 | - | 27760321 | HT29 | viability after 10 days | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -0.3297431497545523 | [759,592] | [800,532,677] | -4 | hSpCas9 | negative selection | 5344542 | 272705 | 272727 | 5 | + | 27760321 | HT29 | viability after 10 days | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | 1.8950314196685745 | [9,7] | [62,0,59] | 9 | hSpCas9 | negative selection | 5344543 | 272746 | 272768 | 5 | - | 27760321 | HT29 | viability after 10 days | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.3977739423856296 | [406,317] | [381,393,257] | -5 | hSpCas9 | negative selection | 5344544 | 271801 | 271823 | 5 | + | 27760321 | MOLM13 | viability | CCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -0.805305076672882 | [412,286] | [108,113] | -5 | hSpCas9 | negative selection | 5428004 | 271816 | 271838 | 5 | - | 27760321 | MOLM13 | viability | CGGTGCCAGGCCGCACCTCTGG | PDCD6 | ENSG00000249915 | -0.0076395441993718505 | [741,759] | [385,454] | 0 | hSpCas9 | negative selection | 5428005 | 272705 | 272727 | 5 | + | 27760321 | MOLM13 | viability | TTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -2.999869873866813 | [18,9] | [0,0] | -9 | hSpCas9 | negative selection | 5428006 | 272746 | 272768 | 5 | - | 27760321 | MOLM13 | viability | GAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.1171204445433245 | [465,406] | [122,104] | -6 | hSpCas9 | negative selection | 5428007 | 271652 | 271675 | 5 | + | 27661255 | K562 | viability | GGAAGCGGAGTCGGCCTGAGAGG | PDCD6 | ENSG00000249915 | 0.14162615613530538 | [1026,1155] | [989,933] | 5 | dCas9-KRAB | negative selection | 5500817 | 271666 | 271689 | 5 | - | 27661255 | K562 | viability | GCAGCGACGAGAGACCTCTCAGG | PDCD6 | ENSG00000249915 | 0.12655011895790702 | [132,200] | [136,150] | 4 | dCas9-KRAB | negative selection | 5500818 | 271901 | 271924 | 5 | - | 27661255 | K562 | viability | GCAGTAGAACCGGCAGGGAACGG | PDCD6 | ENSG00000249915 | -0.019900889709017378 | [257,265] | [235,180] | -1 | dCas9-KRAB | negative selection | 5500819 | 271911 | 271934 | 5 | - | 27661255 | K562 | viability | GGAGGAGGCCGCAGTAGAACCGG | PDCD6 | ENSG00000249915 | 0.06565458598503275 | [766,824] | [764,578] | 2 | dCas9-KRAB | negative selection | 5500820 | 271926 | 271949 | 5 | - | 27661255 | K562 | viability | GACCCGACAGGGGACGGAGGAGG | PDCD6 | ENSG00000249915 | -0.7653926223415897 | [294,219] | [112,128] | -8 | dCas9-KRAB | negative selection | 5500821 | 271936 | 271959 | 5 | - | 27661255 | K562 | viability | GGCCGCGGGGGACCCGACAGGGG | PDCD6 | ENSG00000249915 | 0.09406072551040823 | [570,463] | [518,377] | 3 | dCas9-KRAB | negative selection | 5500822 | 272746 | 272769 | 5 | - | 27260156 | BXPC3 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.656488993113979 | [501] | [298,304,408,321] | -8 | hSpCas9 | negative selection | 5626101 | 272704 | 272727 | 5 | + | 27260156 | BXPC3 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.9592557168021898 | [189] | [100,106,86,113] | -9 | hSpCas9 | negative selection | 5626102 | 272746 | 272769 | 5 | - | 27260156 | A673 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.32893584798861997 | [501] | [595,373,552,406] | -7 | hSpCas9 | negative selection | 5747352 | 272704 | 272727 | 5 | + | 27260156 | A673 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.40127525385491647 | [189] | [221,102,110,267] | -7 | hSpCas9 | negative selection | 5747353 | 272746 | 272769 | 5 | - | 27260156 | A375 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.8454292284755082 | [501] | [425,167,364,323] | -8 | hSpCas9 | negative selection | 5868603 | 272704 | 272727 | 5 | + | 27260156 | A375 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.7643299716339182 | [189] | [111,85,170,144] | -7 | hSpCas9 | negative selection | 5868604 | 272746 | 272769 | 5 | - | 27260156 | COLO741 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.7898790961285842 | [501] | [384,422,309] | -9 | hSpCas9 | negative selection | 5989854 | 272704 | 272727 | 5 | + | 27260156 | COLO741 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.9782023488778351 | [189] | [77,168,118] | -9 | hSpCas9 | negative selection | 5989855 | 272746 | 272769 | 5 | - | 27260156 | CAL120 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.31078099769321677 | [501] | [566,326,623] | -4 | hSpCas9 | negative selection | 6111105 | 272704 | 272727 | 5 | + | 27260156 | CAL120 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.13288398984497607 | [189] | [249,243,158] | -2 | hSpCas9 | negative selection | 6111106 | 272746 | 272769 | 5 | - | 27260156 | CADOES1 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.38495286968989073 | [501] | [360,422,347,295] | -6 | hSpCas9 | negative selection | 6232356 | 272704 | 272727 | 5 | + | 27260156 | CADOES1 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.5090789454735909 | [189] | [156,118,85,134] | -7 | hSpCas9 | negative selection | 6232357 | 272746 | 272769 | 5 | - | 27260156 | EWS502 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.6092149256055838 | [501] | [337,260,325,481] | -7 | hSpCas9 | negative selection | 6353607 | 272704 | 272727 | 5 | + | 27260156 | EWS502 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.6150996934806117 | [189] | [57,132,244,96] | -7 | hSpCas9 | negative selection | 6353608 | 272746 | 272769 | 5 | - | 27260156 | EW8 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.47798513188494895 | [501] | [391,336,136,338] | -7 | hSpCas9 | negative selection | 6474858 | 272704 | 272727 | 5 | + | 27260156 | EW8 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.5967595148590135 | [189] | [142,111,75,84] | -8 | hSpCas9 | negative selection | 6474859 | 272746 | 272769 | 5 | - | 27260156 | CORL105 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.61369354816289 | [501] | [354,439,276,444] | -8 | hSpCas9 | negative selection | 6596109 | 272704 | 272727 | 5 | + | 27260156 | CORL105 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.26781606935266256 | [189] | [171,255,188,120] | -5 | hSpCas9 | negative selection | 6596110 | 272746 | 272769 | 5 | - | 27260156 | HS294T | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.31373275226257036 | [501] | [262,83,108,160] | -4 | hSpCas9 | negative selection | 6717360 | 272704 | 272727 | 5 | + | 27260156 | HS294T | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.6862276760599064 | [189] | [50,40,34,56] | -7 | hSpCas9 | negative selection | 6717361 | 272746 | 272769 | 5 | - | 27260156 | HCC44 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.9798507985410715 | [501] | [228,237,546,184] | -8 | hSpCas9 | negative selection | 6838611 | 272704 | 272727 | 5 | + | 27260156 | HCC44 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.6767839884337545 | [189] | [66,243,144,62] | -7 | hSpCas9 | negative selection | 6838612 | 272746 | 272769 | 5 | - | 27260156 | G402 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.7885857677785921 | [501] | [338,272,293,496] | -7 | hSpCas9 | negative selection | 6959862 | 272704 | 272727 | 5 | + | 27260156 | G402 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.09428739109423234 | [189] | [111,352,187,207] | -1 | hSpCas9 | negative selection | 6959863 | 272746 | 272769 | 5 | - | 27260156 | L33 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.7632531131410366 | [501] | [316,124,211,223] | -9 | hSpCas9 | negative selection | 7081113 | 272704 | 272727 | 5 | + | 27260156 | L33 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.719368608773205 | [189] | [103,34,100,111] | -9 | hSpCas9 | negative selection | 7081114 | 272746 | 272769 | 5 | - | 27260156 | K562 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.085815284670952 | [501] | [211,201,191,229] | -8 | hSpCas9 | negative selection | 7202364 | 272704 | 272727 | 5 | + | 27260156 | K562 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.20291636915993982 | [189] | [391,108,45,65] | -3 | hSpCas9 | negative selection | 7202365 | 272746 | 272769 | 5 | - | 27260156 | HT29 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.7057404676583343 | [501] | [505,279,452,269] | -8 | hSpCas9 | negative selection | 7323615 | 272704 | 272727 | 5 | + | 27260156 | HT29 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.24829981602747342 | [189] | [244,207,201,133] | -5 | hSpCas9 | negative selection | 7323616 | 272746 | 272769 | 5 | - | 27260156 | MHHES1 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.4309837251628427 | [501] | [570,535,269,338] | -7 | hSpCas9 | negative selection | 7444866 | 272704 | 272727 | 5 | + | 27260156 | MHHES1 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.2883563663926503 | [189] | [215,255,136,114] | -5 | hSpCas9 | negative selection | 7444867 | 272746 | 272769 | 5 | - | 27260156 | MEWO | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.26969108347407905 | [501] | [376,430,357] | -5 | hSpCas9 | negative selection | 7566117 | 272704 | 272727 | 5 | + | 27260156 | MEWO | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.5041014450245171 | [189] | [191,103,92] | -8 | hSpCas9 | negative selection | 7566118 | 272746 | 272769 | 5 | - | 27260156 | LNCAPCLONEFGC | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.8471510970648652 | [501] | [152,324,251,277] | -8 | hSpCas9 | negative selection | 7687368 | 272704 | 272727 | 5 | + | 27260156 | LNCAPCLONEFGC | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.6926772780307728 | [189] | [51,151,106,112] | -8 | hSpCas9 | negative selection | 7687369 | 272746 | 272769 | 5 | - | 27260156 | PANC0327 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.9451537483689524 | [501] | [321,212,144,255] | -8 | hSpCas9 | negative selection | 7808619 | 272704 | 272727 | 5 | + | 27260156 | PANC0327 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.15386770985048437 | [189] | [319,46,103,162] | -2 | hSpCas9 | negative selection | 7808620 | 272746 | 272769 | 5 | - | 27260156 | NCIH2009 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.1808137480506808 | [501] | [352,321,260] | -8 | hSpCas9 | negative selection | 7929870 | 272704 | 272727 | 5 | + | 27260156 | NCIH2009 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.9753987895289757 | [189] | [128,58,216] | -8 | hSpCas9 | negative selection | 7929871 | 272746 | 272769 | 5 | - | 27260156 | NCIH1373 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.6978783333275235 | [501] | [223,473,469,44] | -6 | hSpCas9 | negative selection | 8051121 | 272704 | 272727 | 5 | + | 27260156 | NCIH1373 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.8830843586893788 | [189] | [133,88,90,40] | -7 | hSpCas9 | negative selection | 8051122 | 272746 | 272769 | 5 | - | 27260156 | PATU8902 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.9380503425939632 | [501] | [411,348,397,277] | -7 | hSpCas9 | negative selection | 8172372 | 272704 | 272727 | 5 | + | 27260156 | PATU8902 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.25324528903042287 | [189] | [290,113,237,239] | -3 | hSpCas9 | negative selection | 8172373 | 272746 | 272769 | 5 | - | 27260156 | PANC1 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.9004338249966127 | [501] | [249,302,157,223] | -8 | hSpCas9 | negative selection | 8293623 | 272704 | 272727 | 5 | + | 27260156 | PANC1 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.785871013166088 | [189] | [79,109,118,74] | -8 | hSpCas9 | negative selection | 8293624 | 272746 | 272769 | 5 | - | 27260156 | PANC0813 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.9405804237746178 | [501] | [325,285,324,293] | -8 | hSpCas9 | negative selection | 8414874 | 272704 | 272727 | 5 | + | 27260156 | PANC0813 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.5164931489453384 | [189] | [116,131,240,131] | -7 | hSpCas9 | negative selection | 8414875 | 272746 | 272769 | 5 | - | 27260156 | RDES | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.19589392254631113 | [501] | [375,423,589,676] | -3 | hSpCas9 | negative selection | 8536125 | 272704 | 272727 | 5 | + | 27260156 | RDES | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.3162902164820516 | [189] | [182,198,153,150] | -5 | hSpCas9 | negative selection | 8536126 | 272746 | 272769 | 5 | - | 27260156 | PC3 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.7653350755242585 | [501] | [139,280,596,324] | -9 | hSpCas9 | negative selection | 8657376 | 272704 | 272727 | 5 | + | 27260156 | PC3 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.3268920018792023 | [189] | [176,139,215,54] | -6 | hSpCas9 | negative selection | 8657377 | 272746 | 272769 | 5 | - | 27260156 | PATU8988T | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.6653463359268466 | [501] | [187,267,218,566] | -8 | hSpCas9 | negative selection | 8778627 | 272704 | 272727 | 5 | + | 27260156 | PATU8988T | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.7427205886052053 | [189] | [51,198,91,103] | -8 | hSpCas9 | negative selection | 8778628 | 272746 | 272769 | 5 | - | 27260156 | T47D | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.818090854241448 | [501] | [313,355,315,338] | -9 | hSpCas9 | negative selection | 8899878 | 272704 | 272727 | 5 | + | 27260156 | T47D | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.7121869249410047 | [189] | [144,173,100,116] | -8 | hSpCas9 | negative selection | 8899879 | 272746 | 272769 | 5 | - | 27260156 | SU8686 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.42020644304221966 | [501] | [308,327,381,499] | -6 | hSpCas9 | negative selection | 9021129 | 272704 | 272727 | 5 | + | 27260156 | SU8686 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.26637934524001494 | [189] | [190,98,167,173] | -4 | hSpCas9 | negative selection | 9021130 | 272746 | 272769 | 5 | - | 27260156 | SKES1 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.7977645228240307 | [501] | [266,309,294,277] | -9 | hSpCas9 | negative selection | 9142380 | 272704 | 272727 | 5 | + | 27260156 | SKES1 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -1.2741513874726405 | [189] | [58,122,79,55] | -9 | hSpCas9 | negative selection | 9142381 | 272746 | 272769 | 5 | - | 27260156 | TOV112D | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.38224963762734393 | [501] | [368,573,501,148] | -6 | hSpCas9 | negative selection | 9263631 | 272704 | 272727 | 5 | + | 27260156 | TOV112D | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.6532379302773665 | [189] | [101,112,135,128] | -8 | hSpCas9 | negative selection | 9263632 | 272746 | 272769 | 5 | - | 27260156 | TC71 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -0.33407091826950747 | [501] | [342,407,458,502] | -7 | hSpCas9 | negative selection | 9384882 | 272704 | 272727 | 5 | + | 27260156 | TC71 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.2144742593368012 | [189] | [148,142,141,275] | -5 | hSpCas9 | negative selection | 9384883 | 272746 | 272769 | 5 | - | 27260156 | TC32 | viability | GGAGAGAGCTTGCTGAAGCTCGG | PDCD6 | ENSG00000249915 | -1.0378475483043856 | [501] | [230,168,284,253] | -9 | hSpCas9 | negative selection | 9506133 | 272704 | 272727 | 5 | + | 27260156 | TC32 | viability | GTTATAGGGTCGATAAAGACAGG | PDCD6 | ENSG00000249915 | -0.8225257413119338 | [189] | [138,85,100,69] | -9 | hSpCas9 | negative selection | 9506134 | 271725 | 271748 | 5 | - | 28162770 | P31FUJ | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -1.6227487227303918 | [227] | [86] | -7 | hSpCas9 | negative selection | 10208574 | 271800 | 271823 | 5 | + | 28162770 | P31FUJ | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.23140813684616757 | [821] | [1133] | 2 | hSpCas9 | negative selection | 10208575 | 271725 | 271748 | 5 | - | 28162770 | TF1 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | NaN | [NaN] | [17] | 1 | hSpCas9 | negative selection | 10377940 | 271800 | 271823 | 5 | + | 28162770 | TF1 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | NaN | [NaN] | [526] | 1 | hSpCas9 | negative selection | 10377941 | 271725 | 271748 | 5 | - | 28162770 | SKM1 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -1.7813597135246597 | [69] | [35] | -8 | hSpCas9 | negative selection | 10547306 | 271800 | 271823 | 5 | + | 28162770 | SKM1 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -0.8105969347497559 | [251] | [253] | -6 | hSpCas9 | negative selection | 10547307 | 271725 | 271748 | 5 | - | 28162770 | SKM1 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -1.7813597135246597 | [69] | [35] | -8 | hSpCas9 | negative selection | 10716672 | 271800 | 271823 | 5 | + | 28162770 | SKM1 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -0.8105969347497559 | [251] | [253] | -6 | hSpCas9 | negative selection | 10716673 | 271725 | 271748 | 5 | - | 28162770 | PL21 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -1.3786443113027118 | [232] | [38] | -7 | hSpCas9 | negative selection | 10886038 | 271800 | 271823 | 5 | + | 28162770 | PL21 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -0.19748535250271737 | [850] | [322] | -1 | hSpCas9 | negative selection | 10886039 | 271725 | 271748 | 5 | - | 28162770 | P31FUJ | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -1.6227487227303918 | [227] | [86] | -7 | hSpCas9 | negative selection | 11055404 | 271800 | 271823 | 5 | + | 28162770 | P31FUJ | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.23140813684616757 | [821] | [1133] | 2 | hSpCas9 | negative selection | 11055405 | 271725 | 271748 | 5 | - | 28162770 | OCIAML5 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -1.890105931883171 | [268] | [130] | -7 | hSpCas9 | negative selection | 11224770 | 271800 | 271823 | 5 | + | 28162770 | OCIAML5 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.21851410858161602 | [358] | [753] | 1 | hSpCas9 | negative selection | 11224771 | 271725 | 271748 | 5 | - | 28162770 | EOL1 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -1.33986786466162 | [417] | [86] | -7 | hSpCas9 | negative selection | 11394136 | 271800 | 271823 | 5 | + | 28162770 | EOL1 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.13764244832489236 | [1400] | [811] | 1 | hSpCas9 | negative selection | 11394137 | 271725 | 271748 | 5 | - | 28162770 | MOLM13 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -2.2272560369270002 | [271] | [41] | -7 | hSpCas9 | negative selection | 11563502 | 271800 | 271823 | 5 | + | 28162770 | MOLM13 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.3993022962871664 | [1119] | [1067] | 3 | hSpCas9 | negative selection | 11563503 | 271725 | 271748 | 5 | - | 28162770 | HEL | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -0.8541989209235751 | [301] | [106] | -5 | hSpCas9 | negative selection | 11732868 | 271800 | 271823 | 5 | + | 28162770 | HEL | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.7340068895676706 | [979] | [1043] | 6 | hSpCas9 | negative selection | 11732869 | 271725 | 271748 | 5 | - | 28162770 | MV411 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -1.8006567374182696 | [243] | [58] | -8 | hSpCas9 | negative selection | 11902234 | 271800 | 271823 | 5 | + | 28162770 | MV411 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -0.12462866320577204 | [870] | [672] | -1 | hSpCas9 | negative selection | 11902235 | 271725 | 271748 | 5 | - | 28162770 | MONOMAC1 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -3.686421687798479 | [145] | [12] | -9 | hSpCas9 | negative selection | 12071600 | 271800 | 271823 | 5 | + | 28162770 | MONOMAC1 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.08463855648705376 | [486] | [591] | 0 | hSpCas9 | negative selection | 12071601 | 271725 | 271748 | 5 | - | 28162770 | OCIAML2 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -1.7103002380104448 | [48] | [82] | -7 | hSpCas9 | negative selection | 12240966 | 271800 | 271823 | 5 | + | 28162770 | OCIAML2 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | 0.6053880416026161 | [133] | [1129] | 6 | hSpCas9 | negative selection | 12240967 | 271725 | 271748 | 5 | - | 28162770 | OCIAML3 | viability | GCCGGGGCGGTAAGAGTAGGCGG | PDCD6 | ENSG00000249915 | -1.4273577709147118 | [48] | [54] | -7 | hSpCas9 | negative selection | 12410332 | 271800 | 271823 | 5 | + | 28162770 | OCIAML3 | viability | TCCTGTGGAACGTTTTCCAGAGG | PDCD6 | ENSG00000249915 | -1.0425976993140338 | [231] | [339] | -6 | hSpCas9 | negative selection | 12410333 |