Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5174
• Symbol:PDZK1
• Description:PDZ domain containing 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PDZK1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
145687928	145687951	1	-	26472758	Jiyoye	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.008626005015598626	[28]	[21]	0	hSpCas9	negative selection	118636
145687843	145687866	1	-	26472758	Jiyoye	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	1.6966819987008583	[35]	[87]	8	hSpCas9	negative selection	118637
145687867	145687890	1	-	26472758	Jiyoye	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	0.28759376575320084	[175]	[161]	2	hSpCas9	negative selection	118638
145687883	145687906	1	-	26472758	Jiyoye	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.7482122993409404	[104]	[132]	5	hSpCas9	negative selection	118639
145687811	145687834	1	-	26472758	Jiyoye	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	0.6453351187006378	[38]	[45]	5	hSpCas9	negative selection	118640
145686500	145686523	1	-	26472758	Jiyoye	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.8188926979739729	[392]	[167]	-5	hSpCas9	negative selection	118641
145687904	145687927	1	+	26472758	Jiyoye	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.7009065845625837	[92]	[113]	5	hSpCas9	negative selection	118642
145687981	145688004	1	+	26472758	Jiyoye	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	0.827078635956533	[295]	[395]	6	hSpCas9	negative selection	118643
145687960	145687983	1	-	26472758	Jiyoye	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	0.4446500869245362	[37]	[38]	3	hSpCas9	negative selection	118644
145687913	145687936	1	-	26472758	Jiyoye	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	0.9818695467732028	[46]	[69]	6	hSpCas9	negative selection	118645
145687928	145687951	1	-	26472758	KBM7	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.8107164926664634	[119,138]	[67,143]	8	hSpCas9	negative selection	309754
145687843	145687866	1	-	26472758	KBM7	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-0.1818990341377782	[266,354]	[104,154]	-2	hSpCas9	negative selection	309755
145687867	145687890	1	-	26472758	KBM7	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	0.5109298762278048	[451,422]	[367,226]	5	hSpCas9	negative selection	309756
145687883	145687906	1	-	26472758	KBM7	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.024379715403236746	[522,438]	[240,203]	0	hSpCas9	negative selection	309757
145687811	145687834	1	-	26472758	KBM7	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	-0.42547658150872336	[255,250]	[143,39]	-4	hSpCas9	negative selection	309758
145686500	145686523	1	-	26472758	KBM7	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.589022868609306	[1297,1266]	[480,331]	-5	hSpCas9	negative selection	309759
145687904	145687927	1	+	26472758	KBM7	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.27530052650463854	[605,437]	[338,252]	3	hSpCas9	negative selection	309760
145687981	145688004	1	+	26472758	KBM7	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	0.5976513987895355	[1379,1241]	[1171,717]	6	hSpCas9	negative selection	309761
145687960	145687983	1	-	26472758	KBM7	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	0.6990653071220557	[289,340]	[111,361]	7	hSpCas9	negative selection	309762
145687913	145687936	1	-	26472758	KBM7	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	0.0007891815497891308	[323,331]	[159,150]	0	hSpCas9	negative selection	309763
145687928	145687951	1	-	26472758	Raji	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.10738353537359968	[43]	[10]	1	hSpCas9	negative selection	500872
145687843	145687866	1	-	26472758	Raji	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-0.4706925797623168	[208]	[34]	-4	hSpCas9	negative selection	500873
145687867	145687890	1	-	26472758	Raji	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	0.4336117676945874	[200]	[62]	4	hSpCas9	negative selection	500874
145687883	145687906	1	-	26472758	Raji	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.14768958475751154	[252]	[52]	-1	hSpCas9	negative selection	500875
145687811	145687834	1	-	26472758	Raji	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	-0.36392218355198946	[121]	[21]	-3	hSpCas9	negative selection	500876
145686500	145686523	1	-	26472758	Raji	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	0.25223651485907916	[444]	[122]	2	hSpCas9	negative selection	500877
145687904	145687927	1	+	26472758	Raji	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.29745819679935565	[375]	[70]	-2	hSpCas9	negative selection	500878
145687981	145688004	1	+	26472758	Raji	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	-0.47406448117131994	[819]	[136]	-4	hSpCas9	negative selection	500879
145687960	145687983	1	-	26472758	Raji	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	-0.4351436990271601	[133]	[22]	-4	hSpCas9	negative selection	500880
145687913	145687936	1	-	26472758	Raji	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	-0.3317280988841018	[140]	[25]	-3	hSpCas9	negative selection	500881
145687928	145687951	1	-	26472758	K562	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	-0.2567754153621111	[91]	[64]	-2	hSpCas9	negative selection	691990
145687843	145687866	1	-	26472758	K562	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	1.2215787513083356	[381]	[751]	8	hSpCas9	negative selection	691991
145687867	145687890	1	-	26472758	K562	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	0.7800859321308293	[386]	[560]	6	hSpCas9	negative selection	691992
145687883	145687906	1	-	26472758	K562	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.49500069455601026	[542]	[645]	4	hSpCas9	negative selection	691993
145687811	145687834	1	-	26472758	K562	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	-1.4799468297201257	[151]	[45]	-6	hSpCas9	negative selection	691994
145686500	145686523	1	-	26472758	K562	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.7104690727049919	[912]	[470]	-4	hSpCas9	negative selection	691995
145687904	145687927	1	+	26472758	K562	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.539451595490749	[378]	[464]	4	hSpCas9	negative selection	691996
145687981	145688004	1	+	26472758	K562	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	0.23428435053273367	[999]	[992]	1	hSpCas9	negative selection	691997
145687960	145687983	1	-	26472758	K562	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	0.18205284670607336	[259]	[248]	1	hSpCas9	negative selection	691998
145687913	145687936	1	-	26472758	K562	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	0.29625765918606506	[163]	[169]	2	hSpCas9	negative selection	691999
145687937	145687960	1	-	26627737	DLD1	viability	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	1.8330997375585456	[183]	[179,207,223]	9	hSpCas9	negative selection	765639
145687927	145687950	1	-	26627737	DLD1	viability	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.5034329185145848	[795]	[101,234,189]	-5	hSpCas9	negative selection	765640
145687904	145687927	1	+	26627737	DLD1	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.07727198749070263	[290]	[90,111,86]	0	hSpCas9	negative selection	765641
145687937	145687960	1	-	26627737	GBM cells	viability after 5 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.6522739073025604	[174]	[134,159]	8	hSpCas9	negative selection	847954
145687927	145687950	1	-	26627737	GBM cells	viability after 5 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.11752727217584219	[352]	[158,189]	-2	hSpCas9	negative selection	847955
145687904	145687927	1	+	26627737	GBM cells	viability after 5 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.3623143957259286	[131]	[96,84]	5	hSpCas9	negative selection	847956
145687937	145687960	1	-	26627737	GBM cells	viability after 13 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.5117095393544457	[174]	[125,142]	6	hSpCas9	negative selection	930269
145687927	145687950	1	-	26627737	GBM cells	viability after 13 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.24058935400433867	[352]	[176,149]	-3	hSpCas9	negative selection	930270
145687904	145687927	1	+	26627737	GBM cells	viability after 13 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.18517946388120132	[131]	[46,75]	-2	hSpCas9	negative selection	930271
145687937	145687960	1	-	26627737	GBM cells	viability after 21 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.9831846481350055	[174]	[200,175]	8	hSpCas9	negative selection	1012584
145687927	145687950	1	-	26627737	GBM cells	viability after 21 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.41816075041065287	[352]	[142,143]	-4	hSpCas9	negative selection	1012585
145687904	145687927	1	+	26627737	GBM cells	viability after 21 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.14945838532114653	[131]	[60,67]	-1	hSpCas9	negative selection	1012586
145687937	145687960	1	-	26627737	RPE1	viability after 9 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.017749180174114608	[814]	[256,259]	0	hSpCas9	negative selection	1094899
145687927	145687950	1	-	26627737	RPE1	viability after 9 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-1.378381218160727	[1670]	[157,256]	-7	hSpCas9	negative selection	1094900
145687904	145687927	1	+	26627737	RPE1	viability after 9 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.1238033421057293	[614]	[91,285]	-1	hSpCas9	negative selection	1094901
145687937	145687960	1	-	26627737	RPE1	viability after 12 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	-0.3928165015080297	[814]	[141,192]	-3	hSpCas9	negative selection	1177214
145687927	145687950	1	-	26627737	RPE1	viability after 12 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-1.2870466886948526	[1670]	[199,166]	-7	hSpCas9	negative selection	1177215
145687904	145687927	1	+	26627737	RPE1	viability after 12 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.5167605991186957	[614]	[97,133]	-4	hSpCas9	negative selection	1177216
145687937	145687960	1	-	26627737	RPE1	viability after 15 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	-0.36830448463467486	[814]	[200,156]	-2	hSpCas9	negative selection	1259529
145687927	145687950	1	-	26627737	RPE1	viability after 15 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-1.493965403084982	[1670]	[205,130]	-7	hSpCas9	negative selection	1259530
145687904	145687927	1	+	26627737	RPE1	viability after 15 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.07603507596636155	[614]	[217,149]	0	hSpCas9	negative selection	1259531
145687937	145687960	1	-	26627737	RPE1	viability after 18 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	-0.2532330659367565	[814]	[170,198]	-1	hSpCas9	negative selection	1341844
145687927	145687950	1	-	26627737	RPE1	viability after 18 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-1.204352269209493	[1670]	[215,173]	-6	hSpCas9	negative selection	1341845
145687904	145687927	1	+	26627737	RPE1	viability after 18 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.08849579551177578	[614]	[187,121]	0	hSpCas9	negative selection	1341846
145687937	145687960	1	-	26627737	HeLa	viability after 8 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.6990654439219111	[196]	[164,145,113]	6	hSpCas9	negative selection	1424159
145687927	145687950	1	-	26627737	HeLa	viability after 8 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.07747636071241573	[403]	[319,82,132]	0	hSpCas9	negative selection	1424160
145687904	145687927	1	+	26627737	HeLa	viability after 8 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.7703940159050942	[248]	[81,24,85]	-6	hSpCas9	negative selection	1424161
145687937	145687960	1	-	26627737	HeLa	viability after 12 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.6423858489227101	[196]	[127,138,112]	5	hSpCas9	negative selection	1506474
145687927	145687950	1	-	26627737	HeLa	viability after 12 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	0.46736901670126796	[403]	[426,128,152]	4	hSpCas9	negative selection	1506475
145687904	145687927	1	+	26627737	HeLa	viability after 12 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.4694849232419329	[248]	[16,161,32]	-4	hSpCas9	negative selection	1506476
145687937	145687960	1	-	26627737	HeLa	viability after 15 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.8721545218380161	[196]	[117,160,162]	6	hSpCas9	negative selection	1588789
145687927	145687950	1	-	26627737	HeLa	viability after 15 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	0.6140358141121516	[403]	[321,207,221]	5	hSpCas9	negative selection	1588790
145687904	145687927	1	+	26627737	HeLa	viability after 15 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.6669325875228347	[248]	[34,91,64]	-5	hSpCas9	negative selection	1588791
145687937	145687960	1	-	26627737	HeLa	viability after 18 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.8434564135993257	[196]	[72,133,162]	6	hSpCas9	negative selection	1671104
145687927	145687950	1	-	26627737	HeLa	viability after 18 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	0.5955468917596501	[403]	[217,161,221]	5	hSpCas9	negative selection	1671105
145687904	145687927	1	+	26627737	HeLa	viability after 18 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.6305305948970126	[248]	[21,81,64]	-5	hSpCas9	negative selection	1671106
145687937	145687960	1	-	26627737	HCT116	viability after 6 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.9778223193760711	[512]	[85,198]	5	hSpCas9	negative selection	1753419
145687927	145687950	1	-	26627737	HCT116	viability after 6 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	0.5817950117800714	[710]	[136,183]	3	hSpCas9	negative selection	1753420
145687904	145687927	1	+	26627737	HCT116	viability after 6 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.380354989281943	[510]	[169,1]	-2	hSpCas9	negative selection	1753421
145687937	145687960	1	-	26627737	HCT116	viability after 8 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	1.876742746014688	[65]	[106,142,149]	9	hSpCas9	negative selection	1835734
145687927	145687950	1	-	26627737	HCT116	viability after 8 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.3326500649126489	[470]	[223,139,253]	-4	hSpCas9	negative selection	1835735
145687904	145687927	1	+	26627737	HCT116	viability after 8 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.012682704617708263	[195]	[53,140,124]	0	hSpCas9	negative selection	1835736
145687937	145687960	1	-	26627737	HCT116	viability after 9 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	-1.0887153336922641	[512]	[112,25]	-6	hSpCas9	negative selection	1918049
145687927	145687950	1	-	26627737	HCT116	viability after 9 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.541058952698439	[710]	[144,118]	-4	hSpCas9	negative selection	1918050
145687904	145687927	1	+	26627737	HCT116	viability after 9 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.19337917109971509	[510]	[193,125]	1	hSpCas9	negative selection	1918051
145687937	145687960	1	-	26627737	HCT116	viability after 12 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	1.8523812248090907	[65]	[140,151,81]	9	hSpCas9	negative selection	2000364
145687927	145687950	1	-	26627737	HCT116	viability after 12 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	0.02545598269434346	[470]	[225,207,322]	0	hSpCas9	negative selection	2000365
145687904	145687927	1	+	26627737	HCT116	viability after 12 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.3043211781271525	[195]	[106,153,122]	3	hSpCas9	negative selection	2000366
145687937	145687960	1	-	26627737	HCT116	viability after 15 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	2.0664271525093736	[65]	[187,146,144]	9	hSpCas9	negative selection	2082679
145687927	145687950	1	-	26627737	HCT116	viability after 15 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	0.051435042433229605	[470]	[306,158,376]	0	hSpCas9	negative selection	2082680
145687904	145687927	1	+	26627737	HCT116	viability after 15 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.3736810027229035	[195]	[119,85,58]	-4	hSpCas9	negative selection	2082681
145687937	145687960	1	-	26627737	HCT116	viability after 18 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	1.898504417172291	[65]	[120,99,137]	9	hSpCas9	negative selection	2164994
145687927	145687950	1	-	26627737	HCT116	viability after 18 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	1.199645587843745	[470]	[558,533,472]	8	hSpCas9	negative selection	2164995
145687904	145687927	1	+	26627737	HCT116	viability after 18 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.4519040346872848	[195]	[105,26,77]	-4	hSpCas9	negative selection	2164996
145707522	145707545	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCAGCAAACCAAAAGCTCTGG	PDZK1	ENSG00000174827	0.8023937635165079	[219,386]	[87,147]	3	dCas9-VP64	positive selection	2430726
145707543	145707566	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCCACCTGCCTGGCCCTGCGG	PDZK1	ENSG00000174827	1.2436221632840074	[0,3]	[0,0]	5	dCas9-VP64	positive selection	2430727
145707571	145707594	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGAGTGGCTGGCGAGCAGCGG	PDZK1	ENSG00000174827	0.7648599403561452	[158,34]	[53,15]	3	dCas9-VP64	positive selection	2430728
145694801	145694824	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATCGCTTGAACCCGG	PDZK1	ENSG00000174827	0.915813201608152	[93,47]	[29,27]	4	dCas9-VP64	positive selection	2442473
145707522	145707545	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCAGCAAACCAAAAGCTCTGG	PDZK1	ENSG00000174827	0.47884252415426687	[613,211]	[88,283]	4	dCas9-VP64	positive selection	2525981
145707543	145707566	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCCACCTGCCTGGCCCTGCGG	PDZK1	ENSG00000174827	0.36013076837060565	[12,28]	[7,8]	3	dCas9-VP64	positive selection	2525982
145707571	145707594	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGAGTGGCTGGCGAGCAGCGG	PDZK1	ENSG00000174827	0.4849957422360518	[34,9]	[11,7]	4	dCas9-VP64	positive selection	2525983
145694801	145694824	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATCGCTTGAACCCGG	PDZK1	ENSG00000174827	-0.3136691189391476	[37,20]	[8,5]	-3	dCas9-VP64	positive selection	2537728
145686636	145686659	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAAAGCAGTGAAAACACGGGTGG	PDZK1	ENSG00000174827	0.38506938770012555	[2,2]	[3,1]	7	hSpCas9	positive selection	3010624
145686556	145686579	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACACCTCCATTCATCACAGGG	PDZK1	ENSG00000174827	0.2360936221814315	[4,4]	[3,4]	5	hSpCas9	positive selection	3010625
145687928	145687951	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	-0.2419772935876275	[2,2]	[3,0]	-3	hSpCas9	positive selection	3010626
145686519	145686542	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	0.06949821415532006	[3,2]	[4,1]	1	hSpCas9	positive selection	3010627
145686636	145686659	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAAAGCAGTGAAAACACGGGTGG	PDZK1	ENSG00000174827	-0.10275048492557551	[2,2]	[2,1]	-1	hSpCas9	positive selection	3078482
145686556	145686579	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACACCTCCATTCATCACAGGG	PDZK1	ENSG00000174827	-0.6085692008549451	[4,4]	[3,0]	-8	hSpCas9	positive selection	3078483
145687928	145687951	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.04372436899657989	[2,2]	[1,1]	0	hSpCas9	positive selection	3078484
145686519	145686542	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	0.22088793792125727	[3,3]	[2,2]	4	hSpCas9	positive selection	3078485
145682582	145682605	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCTCATAGCCACACCTTGAGG	PDZK1	ENSG00000174827	0.009398698002249677	[151,151]	[0,0]	0	hSpCas9	positive selection	3385307
145680960	145680983	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTTCTTCATCTCCACAATTCGG	PDZK1	ENSG00000174827	-1.3351308258222454	[385,385]	[0,0]	-8	hSpCas9	positive selection	3385308
145681094	145681117	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGTTACAGGTGAAGAAGTCAGG	PDZK1	ENSG00000174827	0.7027373597681978	[93,93]	[0,0]	3	hSpCas9	positive selection	3385309
145686636	145686659	1	-	26780180	HT29	viability (Avana library 4 designs)	GAAAGCAGTGAAAACACGGGTGG	PDZK1	ENSG00000174827	2.46770328352197	[]	[]	8	hSpCas9	negative selection	3448681
145686555	145686578	1	+	26780180	HT29	viability (Avana library 4 designs)	GCACACCTCCATTCATCACAGGG	PDZK1	ENSG00000174827	1.51911681136994	[]	[]	6	hSpCas9	negative selection	3448682
145687928	145687951	1	-	26780180	HT29	viability (Avana library 4 designs)	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	1.2772972902522	[]	[]	5	hSpCas9	negative selection	3448683
145686518	145686541	1	+	26780180	HT29	viability (Avana library 4 designs)	TTCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	2.64422449207793	[]	[]	8	hSpCas9	negative selection	3448684
145687928	145687951	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.0613028315363744	[]	[]	0	hSpCas9	negative selection	3543080
145686518	145686541	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-5.27986507308717	[]	[]	-5	hSpCas9	negative selection	3543081
145686555	145686578	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACACCTCCATTCATCACAGGG	PDZK1	ENSG00000174827	-7.67836584178638	[]	[]	-7	hSpCas9	negative selection	3543082
145686636	145686659	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAAAGCAGTGAAAACACGGGTGG	PDZK1	ENSG00000174827	-8.14132488120078	[]	[]	-7	hSpCas9	negative selection	3543083
145687971	145687994	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAAACTGTCCAAGCAAGAAGGG	PDZK1	ENSG00000174827	-2.76910606214253	[]	[]	-3	hSpCas9	negative selection	3543084
145687982	145688005	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGACAGTTTACATTCTCGGGGG	PDZK1	ENSG00000174827	-1.61979764524697	[]	[]	-2	hSpCas9	negative selection	3543085
145687928	145687951	1	-	26780180	A375	viability (Avana lentiGuide)	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	2.78470855892928	[]	[]	3	hSpCas9	negative selection	3651739
145686518	145686541	1	+	26780180	A375	viability (Avana lentiGuide)	TTCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	14.2130454367872	[]	[]	8	hSpCas9	negative selection	3651740
145686555	145686578	1	+	26780180	A375	viability (Avana lentiGuide)	GCACACCTCCATTCATCACAGGG	PDZK1	ENSG00000174827	6.74654940145523	[]	[]	5	hSpCas9	negative selection	3651741
145686636	145686659	1	-	26780180	A375	viability (Avana lentiGuide)	GAAAGCAGTGAAAACACGGGTGG	PDZK1	ENSG00000174827	16.1486418152688	[]	[]	8	hSpCas9	negative selection	3651742
145687971	145687994	1	-	26780180	A375	viability (Avana lentiGuide)	GTAAACTGTCCAAGCAAGAAGGG	PDZK1	ENSG00000174827	-2.23153876139585	[]	[]	-4	hSpCas9	negative selection	3651743
145687982	145688005	1	+	26780180	A375	viability (Avana lentiGuide)	TGGACAGTTTACATTCTCGGGGG	PDZK1	ENSG00000174827	-1.74161631396476	[]	[]	-3	hSpCas9	negative selection	3651744
145687928	145687951	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	-0.21324356044077813	[4]	[4,2]	-3	hSpCas9	positive selection	3760398
145686518	145686541	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-0.22069604134993526	[5]	[4,3]	-3	hSpCas9	positive selection	3760399
145686555	145686578	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACACCTCCATTCATCACAGGG	PDZK1	ENSG00000174827	-0.6326711042739324	[5]	[3,2]	-7	hSpCas9	positive selection	3760400
145686636	145686659	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAAGCAGTGAAAACACGGGTGG	PDZK1	ENSG00000174827	-0.18941041550501764	[4]	[4,3]	-3	hSpCas9	positive selection	3760401
145687971	145687994	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAAACTGTCCAAGCAAGAAGGG	PDZK1	ENSG00000174827	-0.24111242483927042	[6]	[5,4]	-4	hSpCas9	positive selection	3760402
145687982	145688005	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGACAGTTTACATTCTCGGGGG	PDZK1	ENSG00000174827	-0.12084841679978589	[5]	[5,4]	-2	hSpCas9	positive selection	3760403
145687928	145687951	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.29524309930235554	[4]	[4,5]	7	hSpCas9	positive selection	3869005
145686518	145686541	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-1.00365694756261	[5]	[2,1]	-8	hSpCas9	positive selection	3869006
145686555	145686578	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACACCTCCATTCATCACAGGG	PDZK1	ENSG00000174827	0.15698528368795284	[5]	[5,5]	3	hSpCas9	positive selection	3869007
145686636	145686659	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAAGCAGTGAAAACACGGGTGG	PDZK1	ENSG00000174827	-1.4412617122307536	[3]	[0,0]	-9	hSpCas9	positive selection	3869008
145687971	145687994	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAAACTGTCCAAGCAAGAAGGG	PDZK1	ENSG00000174827	0.1842551320961345	[6]	[6,5]	4	hSpCas9	positive selection	3869009
145687982	145688005	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGACAGTTTACATTCTCGGGGG	PDZK1	ENSG00000174827	-0.04812408971398857	[5]	[4,4]	0	hSpCas9	positive selection	3869010
145686516	145686539	1	+	26780180	A375	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	1.63184577599234	[]	[]	8	hSpCas9	negative selection	3979772
145682625	145682648	1	-	26780180	A375	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	1.21311642340474	[]	[]	6	hSpCas9	negative selection	3979773
145686516	145686539	1	+	26780180	HT29	viability (GeCKOv2 library)	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	2.27719490486113	[]	[]	9	hSpCas9	negative selection	4087738
145682625	145682648	1	-	26780180	HT29	viability (GeCKOv2 library)	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	1.54392054623047	[]	[]	7	hSpCas9	negative selection	4087739
145686516	145686539	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.041809766624375036	[3]	[1,2]	-1	hSpCas9	positive selection	4289640
145682625	145682648	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.020204136989001142	[2]	[1,1]	0	hSpCas9	positive selection	4289642
145687902	145687924	1	+	27760321	OCIAML3	viability	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	1.009173414282428	[735,603]	[888,1258]	9	hSpCas9	negative selection	4426883
145687883	145687905	1	-	27760321	OCIAML3	viability	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.5096616744634973	[294,276]	[184,120]	-5	hSpCas9	negative selection	4426884
145687843	145687865	1	-	27760321	OCIAML3	viability	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	1.1484836847971236	[114,88]	[96,277]	9	hSpCas9	negative selection	4426885
145686621	145686643	1	-	27760321	OCIAML3	viability	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	0.02876814317322618	[266,205]	[218,145]	0	hSpCas9	negative selection	4426886
145686519	145686541	1	+	27760321	OCIAML3	viability	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-0.7631769236805709	[611,479]	[176,344]	-6	hSpCas9	negative selection	4426887
145673673	145673695	1	-	27760321	OCIAML3	viability	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	-0.21332130137886207	[771,702]	[478,520]	-2	hSpCas9	negative selection	4426888
145687902	145687924	1	+	27760321	OCIAML2	viability	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	0.5301540140918468	[735,603]	[724,849]	7	hSpCas9	negative selection	4510346
145687883	145687905	1	-	27760321	OCIAML2	viability	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.4070283705635025	[294,276]	[224,414]	5	hSpCas9	negative selection	4510347
145687843	145687865	1	-	27760321	OCIAML2	viability	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-0.04130063513800897	[114,88]	[73,86]	0	hSpCas9	negative selection	4510348
145686621	145686643	1	-	27760321	OCIAML2	viability	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	-0.6157961957193956	[266,205]	[132,111]	-6	hSpCas9	negative selection	4510349
145686519	145686541	1	+	27760321	OCIAML2	viability	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-0.6775579320699694	[611,479]	[247,308]	-6	hSpCas9	negative selection	4510350
145673673	145673695	1	-	27760321	OCIAML2	viability	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	0.29402453688721186	[771,702]	[595,908]	4	hSpCas9	negative selection	4510351
145687902	145687924	1	+	27760321	MV411	viability	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	0.9012483740660782	[735,603]	[579,1184]	6	hSpCas9	negative selection	4593809
145687883	145687905	1	-	27760321	MV411	viability	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.801251890035304	[294,276]	[83,144]	-5	hSpCas9	negative selection	4593810
145687843	145687865	1	-	27760321	MV411	viability	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-1.8606158259512027	[114,88]	[19,15]	-8	hSpCas9	negative selection	4593811
145686621	145686643	1	-	27760321	MV411	viability	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	-0.7714405588381357	[266,205]	[43,160]	-5	hSpCas9	negative selection	4593812
145686519	145686541	1	+	27760321	MV411	viability	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	0.4849970074254192	[611,479]	[175,988]	3	hSpCas9	negative selection	4593813
145673673	145673695	1	-	27760321	MV411	viability	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	0.18898432531718767	[771,702]	[414,763]	1	hSpCas9	negative selection	4593814
145687902	145687924	1	+	27760321	HL60	viability	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	0.5741153144863902	[735,603]	[906,708]	6	hSpCas9	negative selection	4677272
145687883	145687905	1	-	27760321	HL60	viability	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.03650841659761417	[294,276]	[215,264]	0	hSpCas9	negative selection	4677273
145687843	145687865	1	-	27760321	HL60	viability	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.43745439520141916	[114,88]	[145,75]	5	hSpCas9	negative selection	4677274
145686621	145686643	1	-	27760321	HL60	viability	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	0.39286321907740906	[266,205]	[145,363]	5	hSpCas9	negative selection	4677275
145686519	145686541	1	+	27760321	HL60	viability	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-1.0940664129967215	[611,479]	[208,205]	-8	hSpCas9	negative selection	4677276
145673673	145673695	1	-	27760321	HL60	viability	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	-0.2414182181074067	[771,702]	[420,602]	-3	hSpCas9	negative selection	4677277
145687902	145687924	1	+	27760321	HT1080	viability	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	0.753501834113086	[603,471]	[157,583]	4	hSpCas9	negative selection	4760735
145687883	145687905	1	-	27760321	HT1080	viability	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-2.6996415212393474	[276,215]	[6,23]	-7	hSpCas9	negative selection	4760736
145687843	145687865	1	-	27760321	HT1080	viability	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-0.09622816122490407	[88,69]	[0,60]	0	hSpCas9	negative selection	4760737
145686621	145686643	1	-	27760321	HT1080	viability	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	1.084245453740159	[205,160]	[112,200]	6	hSpCas9	negative selection	4760738
145686519	145686541	1	+	27760321	HT1080	viability	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-0.4878410240044044	[479,374]	[14,237]	-2	hSpCas9	negative selection	4760739
145673673	145673695	1	-	27760321	HT1080	viability	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	0.3037631006378525	[702,548]	[335,276]	1	hSpCas9	negative selection	4760740
145687902	145687924	1	+	27760321	HT29	viability after 7 days	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	0.3243142865931222	[603,471]	[1159,737,744]	5	hSpCas9	negative selection	4844198
145687883	145687905	1	-	27760321	HT29	viability after 7 days	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.219973008793669	[276,215]	[351,384,95]	-3	hSpCas9	negative selection	4844199
145687843	145687865	1	-	27760321	HT29	viability after 7 days	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.29603192742154194	[88,69]	[218,114,57]	4	hSpCas9	negative selection	4844200
145686621	145686643	1	-	27760321	HT29	viability after 7 days	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	-0.010006950664285919	[205,160]	[330,201,184]	0	hSpCas9	negative selection	4844201
145686519	145686541	1	+	27760321	HT29	viability after 7 days	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-0.31217269743324655	[479,374]	[422,308,587]	-4	hSpCas9	negative selection	4844202
145673673	145673695	1	-	27760321	HT29	viability after 7 days	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	0.29506989909421644	[702,548]	[842,899,1190]	4	hSpCas9	negative selection	4844203
145687902	145687924	1	+	27760321	HT29	viability after 25 days	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	0.5900584565636883	[603,471]	[924,893,959]	6	hSpCas9	negative selection	4927661
145687883	145687905	1	-	27760321	HT29	viability after 25 days	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.893856271164336	[276,215]	[97,181,180]	-6	hSpCas9	negative selection	4927662
145687843	145687865	1	-	27760321	HT29	viability after 25 days	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-0.11449650578621018	[88,69]	[104,47,98]	-1	hSpCas9	negative selection	4927663
145686621	145686643	1	-	27760321	HT29	viability after 25 days	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	-0.1843156127361989	[205,160]	[192,96,271]	-2	hSpCas9	negative selection	4927664
145686519	145686541	1	+	27760321	HT29	viability after 25 days	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-0.21872922566382408	[479,374]	[336,430,504]	-2	hSpCas9	negative selection	4927665
145673673	145673695	1	-	27760321	HT29	viability after 25 days	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	-0.11646289683496303	[702,548]	[583,658,749]	-1	hSpCas9	negative selection	4927666
145687902	145687924	1	+	27760321	HT29	viability after 22 days	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	0.5899008853925644	[603,471]	[850,1010,948]	6	hSpCas9	negative selection	5011124
145687883	145687905	1	-	27760321	HT29	viability after 22 days	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.7790725602013654	[276,215]	[195,170,129]	-6	hSpCas9	negative selection	5011125
145687843	145687865	1	-	27760321	HT29	viability after 22 days	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.0647174777944679	[88,69]	[137,91,56]	0	hSpCas9	negative selection	5011126
145686621	145686643	1	-	27760321	HT29	viability after 22 days	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	-0.4036824996058854	[205,160]	[123,102,255]	-4	hSpCas9	negative selection	5011127
145686519	145686541	1	+	27760321	HT29	viability after 22 days	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-0.07158202485562776	[479,374]	[263,630,521]	0	hSpCas9	negative selection	5011128
145673673	145673695	1	-	27760321	HT29	viability after 22 days	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	0.1821532820649603	[702,548]	[745,722,997]	1	hSpCas9	negative selection	5011129
145687902	145687924	1	+	27760321	HT29	viability after 19 days	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	0.4618376221615502	[603,471]	[1043,629,886]	4	hSpCas9	negative selection	5094587
145687883	145687905	1	-	27760321	HT29	viability after 19 days	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.33757813657438973	[276,215]	[354,106,220]	-3	hSpCas9	negative selection	5094588
145687843	145687865	1	-	27760321	HT29	viability after 19 days	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.2980829347588738	[88,69]	[155,96,87]	3	hSpCas9	negative selection	5094589
145686621	145686643	1	-	27760321	HT29	viability after 19 days	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	0.03469787460872453	[205,160]	[218,150,272]	0	hSpCas9	negative selection	5094590
145686519	145686541	1	+	27760321	HT29	viability after 19 days	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-0.4037214216386321	[479,374]	[280,199,608]	-4	hSpCas9	negative selection	5094591
145673673	145673695	1	-	27760321	HT29	viability after 19 days	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	0.46577010551297016	[702,548]	[964,708,1277]	4	hSpCas9	negative selection	5094592
145687902	145687924	1	+	27760321	HT29	viability after 16 days	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	0.5187821595515615	[603,471]	[1200,717,703]	6	hSpCas9	negative selection	5178050
145687883	145687905	1	-	27760321	HT29	viability after 16 days	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-1.1264950425559852	[276,215]	[143,71,165]	-7	hSpCas9	negative selection	5178051
145687843	145687865	1	-	27760321	HT29	viability after 16 days	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-0.9419406591335688	[88,69]	[114,24,5]	-7	hSpCas9	negative selection	5178052
145686621	145686643	1	-	27760321	HT29	viability after 16 days	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	-0.44520258499126486	[205,160]	[238,24,199]	-4	hSpCas9	negative selection	5178053
145686519	145686541	1	+	27760321	HT29	viability after 16 days	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-0.47376003093430064	[479,374]	[573,149,335]	-5	hSpCas9	negative selection	5178054
145673673	145673695	1	-	27760321	HT29	viability after 16 days	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	-0.21717001419620985	[702,548]	[815,434,580]	-2	hSpCas9	negative selection	5178055
145687902	145687924	1	+	27760321	HT29	viability after 13 days	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	0.3205749195083246	[603,471]	[808,778,751]	4	hSpCas9	negative selection	5261513
145687883	145687905	1	-	27760321	HT29	viability after 13 days	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.38167529614060913	[276,215]	[211,287,161]	-4	hSpCas9	negative selection	5261514
145687843	145687865	1	-	27760321	HT29	viability after 13 days	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.23854066177483602	[88,69]	[102,189,37]	3	hSpCas9	negative selection	5261515
145686621	145686643	1	-	27760321	HT29	viability after 13 days	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	-0.5329481696534573	[205,160]	[239,67,133]	-5	hSpCas9	negative selection	5261516
145686519	145686541	1	+	27760321	HT29	viability after 13 days	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	0.16931976030204265	[479,374]	[631,364,668]	2	hSpCas9	negative selection	5261517
145673673	145673695	1	-	27760321	HT29	viability after 13 days	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	-0.02570352015874844	[702,548]	[557,740,833]	0	hSpCas9	negative selection	5261518
145687902	145687924	1	+	27760321	HT29	viability after 10 days	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	0.27164456565994477	[603,471]	[755,900,778]	3	hSpCas9	negative selection	5344976
145687883	145687905	1	-	27760321	HT29	viability after 10 days	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.5156041025771226	[276,215]	[298,101,240]	-6	hSpCas9	negative selection	5344977
145687843	145687865	1	-	27760321	HT29	viability after 10 days	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.438692626089739	[88,69]	[80,122,197]	6	hSpCas9	negative selection	5344978
145686621	145686643	1	-	27760321	HT29	viability after 10 days	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	-0.37656787981877726	[205,160]	[311,126,90]	-5	hSpCas9	negative selection	5344979
145686519	145686541	1	+	27760321	HT29	viability after 10 days	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-0.021435207078091018	[479,374]	[416,440,712]	0	hSpCas9	negative selection	5344980
145673673	145673695	1	-	27760321	HT29	viability after 10 days	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	-0.003782315123545432	[702,548]	[608,963,770]	0	hSpCas9	negative selection	5344981
145687902	145687924	1	+	27760321	MOLM13	viability	CTTCTCAACCACCCGGACCAGG	PDZK1	ENSG00000174827	1.0331103180494259	[735,603]	[912,647]	7	hSpCas9	negative selection	5428439
145687883	145687905	1	-	27760321	MOLM13	viability	AAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.6423056236983029	[294,276]	[217,280]	4	hSpCas9	negative selection	5428440
145687843	145687865	1	-	27760321	MOLM13	viability	ACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-2.650048379729221	[114,88]	[0,15]	-8	hSpCas9	negative selection	5428441
145686621	145686643	1	-	27760321	MOLM13	viability	CGGGTGGACTTGAAAGAGTTGG	PDZK1	ENSG00000174827	-1.3310643204432249	[266,205]	[90,19]	-6	hSpCas9	negative selection	5428442
145686519	145686541	1	+	27760321	MOLM13	viability	TCACGAGATAGCAGAGCCGGGG	PDZK1	ENSG00000174827	-0.7999408521338387	[611,479]	[104,235]	-5	hSpCas9	negative selection	5428443
145673673	145673695	1	-	27760321	MOLM13	viability	ATGCGATTCGGGGTCTGCCAGG	PDZK1	ENSG00000174827	-0.9018573790783945	[771,702]	[261,188]	-5	hSpCas9	negative selection	5428444
145706938	145706961	1	-	27661255	K562	viability	GGACCTTCCTACTGATACAGGGG	PDZK1	ENSG00000174827	0.05186815488513763	[1888,1846]	[1602,1499]	1	dCas9-KRAB	negative selection	5501140
145707298	145707321	1	+	27661255	K562	viability	GGACACGAGCAGTTCTTACCTGG	PDZK1	ENSG00000174827	0.06275473114510619	[690,898]	[718,609]	2	dCas9-KRAB	negative selection	5501141
145707277	145707300	1	+	27661255	K562	viability	GGTGGCCAGCACCCTCAAGGAGG	PDZK1	ENSG00000174827	0.22911072119199227	[199,352]	[231,276]	7	dCas9-KRAB	negative selection	5501142
145686516	145686539	1	+	27260156	BXPC3	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.11458593997212284	[543]	[421,496,580,623]	-3	hSpCas9	negative selection	5562100
145682625	145682648	1	-	27260156	BXPC3	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.4939262364317505	[199]	[338,234,303,296]	9	hSpCas9	negative selection	5562102
145686516	145686539	1	+	27260156	A673	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.018841930735015944	[543]	[842,524,548,689]	0	hSpCas9	negative selection	5683351
145682625	145682648	1	-	27260156	A673	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.44733200936929907	[199]	[338,329,335,303]	8	hSpCas9	negative selection	5683353
145686516	145686539	1	+	27260156	A375	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.25837834936263837	[543]	[682,489,569,391]	-4	hSpCas9	negative selection	5804602
145682625	145682648	1	-	27260156	A375	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.08494024418364554	[199]	[226,221,188,239]	-1	hSpCas9	negative selection	5804604
145686516	145686539	1	+	27260156	COLO741	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	0.21510789535016803	[543]	[620,775,991]	4	hSpCas9	negative selection	5925853
145682625	145682648	1	-	27260156	COLO741	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.4272783537072893	[199]	[312,362,350]	8	hSpCas9	negative selection	5925855
145686516	145686539	1	+	27260156	CAL120	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.5400343317723324	[543]	[359,630,390]	-6	hSpCas9	negative selection	6047104
145682625	145682648	1	-	27260156	CAL120	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.9273429904936044	[199]	[433,516,462]	9	hSpCas9	negative selection	6047106
145686516	145686539	1	+	27260156	CADOES1	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.25189972211668626	[543]	[441,411,356,490]	-4	hSpCas9	negative selection	6168355
145682625	145682648	1	-	27260156	CADOES1	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.3528052862416772	[199]	[166,269,260,252]	6	hSpCas9	negative selection	6168357
145686516	145686539	1	+	27260156	EWS502	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.01300364839975604	[543]	[464,588,531,717]	0	hSpCas9	negative selection	6289606
145682625	145682648	1	-	27260156	EWS502	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.4319440350975796	[199]	[370,297,264,189]	7	hSpCas9	negative selection	6289608
145686516	145686539	1	+	27260156	EW8	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	0.16348479751638492	[543]	[601,325,544,502]	3	hSpCas9	negative selection	6410857
145682625	145682648	1	-	27260156	EW8	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.19636450023743257	[199]	[273,132,142,208]	3	hSpCas9	negative selection	6410859
145686516	145686539	1	+	27260156	CORL105	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	0.13737844909937083	[543]	[691,718,743,652]	2	hSpCas9	negative selection	6532108
145682625	145682648	1	-	27260156	CORL105	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.22120443805814682	[199]	[297,340,306,150]	4	hSpCas9	negative selection	6532110
145686516	145686539	1	+	27260156	HS294T	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	0.1773122734779041	[543]	[163,357,186,245]	2	hSpCas9	negative selection	6653359
145682625	145682648	1	-	27260156	HS294T	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.052358348034743374	[199]	[43,69,101,113]	0	hSpCas9	negative selection	6653361
145686516	145686539	1	+	27260156	HCC44	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.39054270781266487	[543]	[486,303,738,416]	-6	hSpCas9	negative selection	6774610
145682625	145682648	1	-	27260156	HCC44	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.34701820240602554	[199]	[142,176,243,154]	-5	hSpCas9	negative selection	6774612
145686516	145686539	1	+	27260156	G402	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	0.3284051044729951	[543]	[535,1177,384,1190]	4	hSpCas9	negative selection	6895861
145682625	145682648	1	-	27260156	G402	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.7676727844800619	[199]	[159,72,170,165]	-7	hSpCas9	negative selection	6895863
145686516	145686539	1	+	27260156	L33	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	0.09799896535108085	[543]	[550,248,410,517]	2	hSpCas9	negative selection	7017112
145682625	145682648	1	-	27260156	L33	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.7152583667619458	[199]	[333,134,228,285]	9	hSpCas9	negative selection	7017114
145686516	145686539	1	+	27260156	K562	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.6394164610652487	[543]	[517,415,290,64]	-6	hSpCas9	negative selection	7138363
145682625	145682648	1	-	27260156	K562	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.3830246107333828	[199]	[47,215,217,66]	-5	hSpCas9	negative selection	7138365
145686516	145686539	1	+	27260156	HT29	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.18224940763291908	[543]	[761,513,557,509]	-4	hSpCas9	negative selection	7259614
145682625	145682648	1	-	27260156	HT29	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.18995885348975117	[199]	[348,315,324,142]	3	hSpCas9	negative selection	7259616
145686516	145686539	1	+	27260156	MHHES1	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.20052620571175162	[543]	[546,720,501,401]	-4	hSpCas9	negative selection	7380865
145682625	145682648	1	-	27260156	MHHES1	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.13592693189333938	[199]	[185,273,176,186]	-3	hSpCas9	negative selection	7380867
145686516	145686539	1	+	27260156	MEWO	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	0.10782154516931977	[543]	[499,714,419]	2	hSpCas9	negative selection	7502116
145682625	145682648	1	-	27260156	MEWO	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.5060145143908259	[199]	[342,281,186]	8	hSpCas9	negative selection	7502118
145686516	145686539	1	+	27260156	LNCAPCLONEFGC	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.10782758584056887	[543]	[427,469,432,493]	-2	hSpCas9	negative selection	7623367
145682625	145682648	1	-	27260156	LNCAPCLONEFGC	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.23672842719732468	[199]	[247,132,331,162]	3	hSpCas9	negative selection	7623369
145686516	145686539	1	+	27260156	PANC0327	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.32273179839266164	[543]	[451,304,278,524]	-5	hSpCas9	negative selection	7744618
145682625	145682648	1	-	27260156	PANC0327	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.5006391923095632	[199]	[199,296,134,362]	7	hSpCas9	negative selection	7744620
145686516	145686539	1	+	27260156	NCIH2009	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.20389261965017605	[543]	[898,482,646]	-3	hSpCas9	negative selection	7865869
145682625	145682648	1	-	27260156	NCIH2009	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.22855821219966455	[199]	[399,326,268]	3	hSpCas9	negative selection	7865871
145686516	145686539	1	+	27260156	NCIH1373	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.17850865998852242	[543]	[396,432,405,244]	-2	hSpCas9	negative selection	7987120
145682625	145682648	1	-	27260156	NCIH1373	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.22903486826824504	[199]	[182,344,93,31]	-2	hSpCas9	negative selection	7987122
145686516	145686539	1	+	27260156	PATU8902	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.006528659531942815	[543]	[678,1251,557,550]	0	hSpCas9	negative selection	8108371
145682625	145682648	1	-	27260156	PATU8902	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.8826992816568753	[199]	[93,266,111,139]	-7	hSpCas9	negative selection	8108373
145686516	145686539	1	+	27260156	PANC1	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.1157249216205122	[543]	[477,472,411,371]	-2	hSpCas9	negative selection	8229622
145682625	145682648	1	-	27260156	PANC1	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.45477660853106694	[199]	[158,309,184,290]	7	hSpCas9	negative selection	8229624
145686516	145686539	1	+	27260156	PANC0813	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.32492645121425673	[543]	[508,498,406,617]	-5	hSpCas9	negative selection	8350873
145682625	145682648	1	-	27260156	PANC0813	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.1587821177612425	[199]	[232,212,162,232]	-3	hSpCas9	negative selection	8350875
145686516	145686539	1	+	27260156	RDES	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.41461950615962	[543]	[401,400,526,571]	-6	hSpCas9	negative selection	8472124
145682625	145682648	1	-	27260156	RDES	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.4497253060646367	[199]	[155,162,153,202]	-6	hSpCas9	negative selection	8472126
145686516	145686539	1	+	27260156	PC3	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.07070471266824846	[543]	[433,297,804,629]	-1	hSpCas9	negative selection	8593375
145682625	145682648	1	-	27260156	PC3	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.31209339615359	[199]	[170,197,463,251]	6	hSpCas9	negative selection	8593377
145686516	145686539	1	+	27260156	PATU8988T	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	0.041030331143636106	[543]	[330,337,428,1091]	0	hSpCas9	negative selection	8714626
145682625	145682648	1	-	27260156	PATU8988T	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.3708153574255013	[199]	[242,226,169,367]	6	hSpCas9	negative selection	8714628
145686516	145686539	1	+	27260156	T47D	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.16221148138129357	[543]	[568,548,571,576]	-4	hSpCas9	negative selection	8835877
145682625	145682648	1	-	27260156	T47D	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.22289544517414628	[199]	[220,258,345,260]	5	hSpCas9	negative selection	8835879
145686516	145686539	1	+	27260156	SU8686	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	0.26132333984422296	[543]	[500,556,853,713]	4	hSpCas9	negative selection	8957128
145682625	145682648	1	-	27260156	SU8686	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.6800305267220873	[199]	[327,271,301,380]	9	hSpCas9	negative selection	8957130
145686516	145686539	1	+	27260156	SKES1	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.03029164479901364	[543]	[578,610,513,442]	0	hSpCas9	negative selection	9078379
145682625	145682648	1	-	27260156	SKES1	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.5412800344151725	[199]	[308,306,305,245]	9	hSpCas9	negative selection	9078381
145686516	145686539	1	+	27260156	TOV112D	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.004078262777744868	[543]	[593,744,516,374]	0	hSpCas9	negative selection	9199630
145682625	145682648	1	-	27260156	TOV112D	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.07028760939200929	[199]	[208,103,202,225]	-1	hSpCas9	negative selection	9199632
145686516	145686539	1	+	27260156	TC71	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.036331171047211536	[543]	[514,585,569,606]	-1	hSpCas9	negative selection	9320881
145682625	145682648	1	-	27260156	TC71	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	0.24970968574795482	[199]	[219,232,295,270]	6	hSpCas9	negative selection	9320883
145686516	145686539	1	+	27260156	TC32	viability	CCTTCACGAGATAGCAGAGCCGG	PDZK1	ENSG00000174827	-0.4421299196086931	[543]	[414,234,462,436]	-7	hSpCas9	negative selection	9442132
145682625	145682648	1	-	27260156	TC32	viability	CTCTCTTCCAGGTAAAAAGGGGG	PDZK1	ENSG00000174827	-0.17993339194110192	[199]	[166,108,242,169]	-3	hSpCas9	negative selection	9442134
145687937	145687960	1	-	27869803	HPAFII	viability after 27 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.575855405044885	[178]	[172,112,NaN]	5	hSpCas9	negative selection	9528616
145687927	145687950	1	-	27869803	HPAFII	viability after 27 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	0.22664759145425373	[398]	[137,334,NaN]	1	hSpCas9	negative selection	9528617
145687904	145687927	1	+	27869803	HPAFII	viability after 27 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.8564194254544646	[135]	[177,88,NaN]	7	hSpCas9	negative selection	9528618
145687937	145687960	1	-	27869803	HPAFII	viability after 15 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	-0.053146902869021795	[178]	[206,171,NaN]	0	hSpCas9	negative selection	9611065
145687927	145687950	1	-	27869803	HPAFII	viability after 15 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.4810786125864215	[398]	[194,376,NaN]	-5	hSpCas9	negative selection	9611066
145687904	145687927	1	+	27869803	HPAFII	viability after 15 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.7873491179736439	[135]	[390,165,NaN]	8	hSpCas9	negative selection	9611067
145687937	145687960	1	-	27869803	ASPC1	viability after 36 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	1.2382057658476975	[336]	[277,103,411]	9	hSpCas9	negative selection	9693514
145687927	145687950	1	-	27869803	ASPC1	viability after 36 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.366551156541318	[938]	[64,202,424]	-4	hSpCas9	negative selection	9693515
145687904	145687927	1	+	27869803	ASPC1	viability after 36 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.08947606858965562	[398]	[210,192,66]	0	hSpCas9	negative selection	9693516
145687937	145687960	1	-	27869803	PATU8988S	viability after 35 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.1881711843758217	[340]	[143,168,NaN]	2	hSpCas9	negative selection	9775963
145687927	145687950	1	-	27869803	PATU8988S	viability after 35 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.48928874167503816	[642]	[176,191,NaN]	-5	hSpCas9	negative selection	9775964
145687904	145687927	1	+	27869803	PATU8988S	viability after 35 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.06924016019269796	[338]	[188,70,NaN]	0	hSpCas9	negative selection	9775965
145687937	145687960	1	-	27869803	PATU8988S	viability after 31 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.0061595044803508525	[340]	[103,177,NaN]	0	hSpCas9	negative selection	9858412
145687927	145687950	1	-	27869803	PATU8988S	viability after 31 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.39331805075678317	[642]	[247,127,NaN]	-4	hSpCas9	negative selection	9858413
145687904	145687927	1	+	27869803	PATU8988S	viability after 31 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.6291278693124708	[338]	[82,92,NaN]	-6	hSpCas9	negative selection	9858414
145687937	145687960	1	-	27869803	HPAFII	viability after 35 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.9967948579574394	[178]	[201,156,NaN]	6	hSpCas9	negative selection	9940861
145687927	145687950	1	-	27869803	HPAFII	viability after 35 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	0.1745085205377267	[398]	[155,308,NaN]	1	hSpCas9	negative selection	9940862
145687904	145687927	1	+	27869803	HPAFII	viability after 35 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	1.3264164556545741	[135]	[198,142,NaN]	8	hSpCas9	negative selection	9940863
145687937	145687960	1	-	27869803	HPAFII	viability after 31 days	CTTCTTCCTGCGAATTGAGAAGG	PDZK1	ENSG00000174827	0.6772042964150744	[178]	[185,132,NaN]	5	hSpCas9	negative selection	10023310
145687927	145687950	1	-	27869803	HPAFII	viability after 31 days	CGAATTGAGAAGGACACCGAGGG	PDZK1	ENSG00000174827	-0.36298296880556885	[398]	[64,292,NaN]	-2	hSpCas9	negative selection	10023311
145687904	145687927	1	+	27869803	HPAFII	viability after 31 days	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.9111025029078236	[135]	[132,154,NaN]	6	hSpCas9	negative selection	10023312
145687928	145687951	1	-	28162770	P31FUJ	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.9276624677788676	[33]	[75]	9	hSpCas9	negative selection	10209372
145687843	145687866	1	-	28162770	P31FUJ	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.08652409528470362	[221]	[276]	0	hSpCas9	negative selection	10209373
145687867	145687890	1	-	28162770	P31FUJ	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	0.17229249161688664	[181]	[240]	1	hSpCas9	negative selection	10209374
145687883	145687906	1	-	28162770	P31FUJ	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.22546022907321048	[195]	[196]	-2	hSpCas9	negative selection	10209375
145687811	145687834	1	-	28162770	P31FUJ	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	0.3856350008578655	[70]	[108]	4	hSpCas9	negative selection	10209376
145686500	145686523	1	-	28162770	P31FUJ	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.5191063895710196	[349]	[286]	-4	hSpCas9	negative selection	10209377
145687904	145687927	1	+	28162770	P31FUJ	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.018120624741548352	[267]	[310]	0	hSpCas9	negative selection	10209378
145687981	145688004	1	+	28162770	P31FUJ	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	0.056175468671697315	[743]	[908]	0	hSpCas9	negative selection	10209379
145687960	145687983	1	-	28162770	P31FUJ	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	0.7309342515988497	[140]	[274]	8	hSpCas9	negative selection	10209380
145687913	145687936	1	-	28162770	P31FUJ	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	0.15020146722475186	[147]	[192]	1	hSpCas9	negative selection	10209381
145687928	145687951	1	-	28162770	TF1	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10378738
145687843	145687866	1	-	28162770	TF1	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10378739
145687867	145687890	1	-	28162770	TF1	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	NaN	[NaN]	[187]	1	hSpCas9	negative selection	10378740
145687883	145687906	1	-	28162770	TF1	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	NaN	[NaN]	[184]	1	hSpCas9	negative selection	10378741
145687811	145687834	1	-	28162770	TF1	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10378742
145686500	145686523	1	-	28162770	TF1	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	NaN	[NaN]	[190]	1	hSpCas9	negative selection	10378743
145687904	145687927	1	+	28162770	TF1	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10378744
145687981	145688004	1	+	28162770	TF1	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	NaN	[NaN]	[365]	1	hSpCas9	negative selection	10378745
145687960	145687983	1	-	28162770	TF1	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	NaN	[NaN]	[256]	1	hSpCas9	negative selection	10378746
145687913	145687936	1	-	28162770	TF1	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	NaN	[NaN]	[229]	1	hSpCas9	negative selection	10378747
145687928	145687951	1	-	28162770	SKM1	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.3384629741712406	[16]	[37]	3	hSpCas9	negative selection	10548104
145687843	145687866	1	-	28162770	SKM1	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.7629608026991506	[42]	[128]	7	hSpCas9	negative selection	10548105
145687867	145687890	1	-	28162770	SKM1	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	-0.27451390271951237	[51]	[75]	-2	hSpCas9	negative selection	10548106
145687883	145687906	1	-	28162770	SKM1	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.06696698958925071	[53]	[99]	0	hSpCas9	negative selection	10548107
145687811	145687834	1	-	28162770	SKM1	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	-0.05148354414477274	[16]	[28]	0	hSpCas9	negative selection	10548108
145686500	145686523	1	-	28162770	SKM1	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.4186460037907971	[92]	[122]	-3	hSpCas9	negative selection	10548109
145687904	145687927	1	+	28162770	SKM1	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.021272798290541406	[67]	[121]	0	hSpCas9	negative selection	10548110
145687981	145688004	1	+	28162770	SKM1	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	-0.5504052786847878	[139]	[168]	-4	hSpCas9	negative selection	10548111
145687960	145687983	1	-	28162770	SKM1	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	0.24212863939771023	[32]	[68]	2	hSpCas9	negative selection	10548112
145687913	145687936	1	-	28162770	SKM1	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	-0.05417514015103875	[36]	[62]	0	hSpCas9	negative selection	10548113
145687928	145687951	1	-	28162770	SKM1	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.3384629741712406	[16]	[37]	3	hSpCas9	negative selection	10717470
145687843	145687866	1	-	28162770	SKM1	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.7629608026991506	[42]	[128]	7	hSpCas9	negative selection	10717471
145687867	145687890	1	-	28162770	SKM1	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	-0.27451390271951237	[51]	[75]	-2	hSpCas9	negative selection	10717472
145687883	145687906	1	-	28162770	SKM1	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.06696698958925071	[53]	[99]	0	hSpCas9	negative selection	10717473
145687811	145687834	1	-	28162770	SKM1	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	-0.05148354414477274	[16]	[28]	0	hSpCas9	negative selection	10717474
145686500	145686523	1	-	28162770	SKM1	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.4186460037907971	[92]	[122]	-3	hSpCas9	negative selection	10717475
145687904	145687927	1	+	28162770	SKM1	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.021272798290541406	[67]	[121]	0	hSpCas9	negative selection	10717476
145687981	145688004	1	+	28162770	SKM1	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	-0.5504052786847878	[139]	[168]	-4	hSpCas9	negative selection	10717477
145687960	145687983	1	-	28162770	SKM1	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	0.24212863939771023	[32]	[68]	2	hSpCas9	negative selection	10717478
145687913	145687936	1	-	28162770	SKM1	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	-0.05417514015103875	[36]	[62]	0	hSpCas9	negative selection	10717479
145687928	145687951	1	-	28162770	PL21	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	-3.777140309010597	[62]	[1]	-9	hSpCas9	negative selection	10886836
145687843	145687866	1	-	28162770	PL21	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-0.3002893760201685	[115]	[40]	-2	hSpCas9	negative selection	10886837
145687867	145687890	1	-	28162770	PL21	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	-1.2066773779845552	[174]	[32]	-7	hSpCas9	negative selection	10886838
145687883	145687906	1	-	28162770	PL21	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.304670197960627	[172]	[92]	2	hSpCas9	negative selection	10886839
145687811	145687834	1	-	28162770	PL21	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	-0.18318902506218526	[59]	[22]	-1	hSpCas9	negative selection	10886840
145686500	145686523	1	-	28162770	PL21	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	0.40688103571785106	[330]	[190]	3	hSpCas9	negative selection	10886841
145687904	145687927	1	+	28162770	PL21	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.08466239706938417	[233]	[107]	0	hSpCas9	negative selection	10886842
145687981	145688004	1	+	28162770	PL21	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	0.3612449150416226	[473]	[264]	3	hSpCas9	negative selection	10886843
145687960	145687983	1	-	28162770	PL21	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	0.28760245573965953	[127]	[67]	2	hSpCas9	negative selection	10886844
145687913	145687936	1	-	28162770	PL21	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	-0.12178848039804224	[109]	[43]	-1	hSpCas9	negative selection	10886845
145687928	145687951	1	-	28162770	P31FUJ	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.9276624677788676	[33]	[75]	9	hSpCas9	negative selection	11056202
145687843	145687866	1	-	28162770	P31FUJ	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.08652409528470362	[221]	[276]	0	hSpCas9	negative selection	11056203
145687867	145687890	1	-	28162770	P31FUJ	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	0.17229249161688664	[181]	[240]	1	hSpCas9	negative selection	11056204
145687883	145687906	1	-	28162770	P31FUJ	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.22546022907321048	[195]	[196]	-2	hSpCas9	negative selection	11056205
145687811	145687834	1	-	28162770	P31FUJ	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	0.3856350008578655	[70]	[108]	4	hSpCas9	negative selection	11056206
145686500	145686523	1	-	28162770	P31FUJ	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.5191063895710196	[349]	[286]	-4	hSpCas9	negative selection	11056207
145687904	145687927	1	+	28162770	P31FUJ	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.018120624741548352	[267]	[310]	0	hSpCas9	negative selection	11056208
145687981	145688004	1	+	28162770	P31FUJ	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	0.056175468671697315	[743]	[908]	0	hSpCas9	negative selection	11056209
145687960	145687983	1	-	28162770	P31FUJ	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	0.7309342515988497	[140]	[274]	8	hSpCas9	negative selection	11056210
145687913	145687936	1	-	28162770	P31FUJ	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	0.15020146722475186	[147]	[192]	1	hSpCas9	negative selection	11056211
145687928	145687951	1	-	28162770	OCIAML5	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.11991905296640626	[25]	[50]	1	hSpCas9	negative selection	11225568
145687843	145687866	1	-	28162770	OCIAML5	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.5225113211430633	[112]	[292]	4	hSpCas9	negative selection	11225569
145687867	145687890	1	-	28162770	OCIAML5	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	-0.2727728202295329	[84]	[126]	-2	hSpCas9	negative selection	11225570
145687883	145687906	1	-	28162770	OCIAML5	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.16042437331919993	[114]	[231]	1	hSpCas9	negative selection	11225571
145687811	145687834	1	-	28162770	OCIAML5	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	-1.4561378945328576	[37]	[24]	-7	hSpCas9	negative selection	11225572
145686500	145686523	1	-	28162770	OCIAML5	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.8940897857597034	[208]	[202]	-5	hSpCas9	negative selection	11225573
145687904	145687927	1	+	28162770	OCIAML5	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.10249045837483606	[128]	[249]	0	hSpCas9	negative selection	11225574
145687981	145688004	1	+	28162770	OCIAML5	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	-0.5480317024490426	[502]	[620]	-4	hSpCas9	negative selection	11225575
145687960	145687983	1	-	28162770	OCIAML5	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	-0.7493069964387962	[148]	[159]	-5	hSpCas9	negative selection	11225576
145687913	145687936	1	-	28162770	OCIAML5	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	0.24656146186371883	[105]	[226]	2	hSpCas9	negative selection	11225577
145687928	145687951	1	-	28162770	EOL1	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	-2.176990254891528	[102]	[11]	-8	hSpCas9	negative selection	11394934
145687843	145687866	1	-	28162770	EOL1	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-0.029158576155530525	[183]	[94]	0	hSpCas9	negative selection	11394935
145687867	145687890	1	-	28162770	EOL1	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	0.06596752615775736	[300]	[165]	0	hSpCas9	negative selection	11394936
145687883	145687906	1	-	28162770	EOL1	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-0.32241826563560566	[374]	[157]	-2	hSpCas9	negative selection	11394937
145687811	145687834	1	-	28162770	EOL1	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	-0.9103929821589694	[131]	[36]	-6	hSpCas9	negative selection	11394938
145686500	145686523	1	-	28162770	EOL1	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.5878378420214597	[658]	[230]	-4	hSpCas9	negative selection	11394939
145687904	145687927	1	+	28162770	EOL1	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.574963333780307	[315]	[247]	5	hSpCas9	negative selection	11394940
145687981	145688004	1	+	28162770	EOL1	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	-0.47855011439678397	[721]	[272]	-4	hSpCas9	negative selection	11394941
145687960	145687983	1	-	28162770	EOL1	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	1.337146225397961	[147]	[196]	9	hSpCas9	negative selection	11394942
145687913	145687936	1	-	28162770	EOL1	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	-1.0754522284294656	[195]	[48]	-6	hSpCas9	negative selection	11394943
145687928	145687951	1	-	28162770	MOLM13	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	1.0172279725350135	[81]	[119]	7	hSpCas9	negative selection	11564300
145687843	145687866	1	-	28162770	MOLM13	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	1.5758047207114665	[205]	[443]	9	hSpCas9	negative selection	11564301
145687867	145687890	1	-	28162770	MOLM13	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	0.6029393417084314	[213]	[234]	4	hSpCas9	negative selection	11564302
145687883	145687906	1	-	28162770	MOLM13	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	1.0646290500420887	[243]	[368]	7	hSpCas9	negative selection	11564303
145687811	145687834	1	-	28162770	MOLM13	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	0.7168026791337199	[153]	[182]	5	hSpCas9	negative selection	11564304
145686500	145686523	1	-	28162770	MOLM13	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	0.31522917351705093	[487]	[438]	2	hSpCas9	negative selection	11564305
145687904	145687927	1	+	28162770	MOLM13	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.21263232630250417	[406]	[340]	1	hSpCas9	negative selection	11564306
145687981	145688004	1	+	28162770	MOLM13	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	0.6228337503017511	[881]	[981]	5	hSpCas9	negative selection	11564307
145687960	145687983	1	-	28162770	MOLM13	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	-0.44817179995552553	[216]	[114]	-3	hSpCas9	negative selection	11564308
145687913	145687936	1	-	28162770	MOLM13	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	0.21413278929879598	[154]	[129]	1	hSpCas9	negative selection	11564309
145687928	145687951	1	-	28162770	HEL	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	1.5723495041089588	[62]	[119]	9	hSpCas9	negative selection	11733666
145687843	145687866	1	-	28162770	HEL	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	1.0220263063299988	[142]	[185]	8	hSpCas9	negative selection	11733667
145687867	145687890	1	-	28162770	HEL	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	0.5296450531547205	[251]	[232]	4	hSpCas9	negative selection	11733668
145687883	145687906	1	-	28162770	HEL	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	-1.0169914371227715	[296]	[93]	-6	hSpCas9	negative selection	11733669
145687811	145687834	1	-	28162770	HEL	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	1.577362823148333	[78]	[150]	9	hSpCas9	negative selection	11733670
145686500	145686523	1	-	28162770	HEL	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.07110420413410257	[391]	[238]	0	hSpCas9	negative selection	11733671
145687904	145687927	1	+	28162770	HEL	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.14023849147117357	[322]	[227]	1	hSpCas9	negative selection	11733672
145687981	145688004	1	+	28162770	HEL	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	0.06809362226471416	[626]	[420]	0	hSpCas9	negative selection	11733673
145687960	145687983	1	-	28162770	HEL	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	0.20811060436363243	[172]	[127]	1	hSpCas9	negative selection	11733674
145687913	145687936	1	-	28162770	HEL	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	0.34017606197992567	[110]	[89]	3	hSpCas9	negative selection	11733675
145687928	145687951	1	-	28162770	MV411	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.5230719933962027	[37]	[45]	5	hSpCas9	negative selection	11903032
145687843	145687866	1	-	28162770	MV411	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-0.6038607188624256	[174]	[96]	-4	hSpCas9	negative selection	11903033
145687867	145687890	1	-	28162770	MV411	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	1.2241050469521515	[186]	[367]	9	hSpCas9	negative selection	11903034
145687883	145687906	1	-	28162770	MV411	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.311567888202491	[153]	[160]	2	hSpCas9	negative selection	11903035
145687811	145687834	1	-	28162770	MV411	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	0.030206834562106155	[92]	[79]	0	hSpCas9	negative selection	11903036
145686500	145686523	1	-	28162770	MV411	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.21307757901389224	[332]	[241]	-2	hSpCas9	negative selection	11903037
145687904	145687927	1	+	28162770	MV411	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.24189936724134542	[260]	[259]	2	hSpCas9	negative selection	11903038
145687981	145688004	1	+	28162770	MV411	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	0.4547625240302815	[439]	[507]	4	hSpCas9	negative selection	11903039
145687960	145687983	1	-	28162770	MV411	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	0.8284850015005483	[122]	[183]	7	hSpCas9	negative selection	11903040
145687913	145687936	1	-	28162770	MV411	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	0.048891871400695064	[139]	[121]	0	hSpCas9	negative selection	11903041
145687928	145687951	1	-	28162770	MONOMAC1	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	0.0924697701354309	[26]	[32]	0	hSpCas9	negative selection	12072398
145687843	145687866	1	-	28162770	MONOMAC1	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-0.8944740770391224	[119]	[73]	-6	hSpCas9	negative selection	12072399
145687867	145687890	1	-	28162770	MONOMAC1	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	-0.3204192625648357	[121]	[111]	-3	hSpCas9	negative selection	12072400
145687883	145687906	1	-	28162770	MONOMAC1	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.10252343479935411	[116]	[143]	1	hSpCas9	negative selection	12072401
145687811	145687834	1	-	28162770	MONOMAC1	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	0.38792565366160225	[41]	[62]	4	hSpCas9	negative selection	12072402
145686500	145686523	1	-	28162770	MONOMAC1	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.17066143163525616	[270]	[275]	-1	hSpCas9	negative selection	12072403
145687904	145687927	1	+	28162770	MONOMAC1	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.0242530178297361	[186]	[217]	0	hSpCas9	negative selection	12072404
145687981	145688004	1	+	28162770	MONOMAC1	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	-0.6636046469784795	[379]	[274]	-5	hSpCas9	negative selection	12072405
145687960	145687983	1	-	28162770	MONOMAC1	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	0.34839728947496496	[73]	[107]	3	hSpCas9	negative selection	12072406
145687913	145687936	1	-	28162770	MONOMAC1	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	-0.17466903403109935	[63]	[64]	-1	hSpCas9	negative selection	12072407
145687928	145687951	1	-	28162770	OCIAML2	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	-0.9263093090183512	[11]	[34]	-6	hSpCas9	negative selection	12241764
145687843	145687866	1	-	28162770	OCIAML2	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	0.6527525902631209	[20]	[182]	6	hSpCas9	negative selection	12241765
145687867	145687890	1	-	28162770	OCIAML2	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	1.0645015195269885	[26]	[312]	8	hSpCas9	negative selection	12241766
145687883	145687906	1	-	28162770	OCIAML2	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.011021958236698964	[40]	[228]	0	hSpCas9	negative selection	12241767
145687811	145687834	1	-	28162770	OCIAML2	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	2.34699343226927	[9]	[281]	9	hSpCas9	negative selection	12241768
145686500	145686523	1	-	28162770	OCIAML2	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.8221021957435389	[73]	[231]	-5	hSpCas9	negative selection	12241769
145687904	145687927	1	+	28162770	OCIAML2	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	0.8919402541425471	[41]	[431]	8	hSpCas9	negative selection	12241770
145687981	145688004	1	+	28162770	OCIAML2	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	0.27353127032824887	[99]	[669]	2	hSpCas9	negative selection	12241771
145687960	145687983	1	-	28162770	OCIAML2	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	-0.23057873740920665	[28]	[136]	-2	hSpCas9	negative selection	12241772
145687913	145687936	1	-	28162770	OCIAML2	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	-0.9012641795720234	[30]	[91]	-6	hSpCas9	negative selection	12241773
145687928	145687951	1	-	28162770	OCIAML3	viability	GCGAATTGAGAAGGACACCGAGG	PDZK1	ENSG00000174827	1.9909548603969927	[9]	[119]	9	hSpCas9	negative selection	12411130
145687843	145687866	1	-	28162770	OCIAML3	viability	GACAGAGTTCTTAGGATCAATGG	PDZK1	ENSG00000174827	-0.7036321314986616	[40]	[75]	-5	hSpCas9	negative selection	12411131
145687867	145687890	1	-	28162770	OCIAML3	viability	GAGAAGGCTGGCCTTCAAGATGG	PDZK1	ENSG00000174827	-0.0355173509641981	[54]	[161]	0	hSpCas9	negative selection	12411132
145687883	145687906	1	-	28162770	OCIAML3	viability	GAAGTGTAGCCCAGCAGAGAAGG	PDZK1	ENSG00000174827	0.6118966582237158	[43]	[202]	5	hSpCas9	negative selection	12411133
145687811	145687834	1	-	28162770	OCIAML3	viability	GGACAAAGAAGAACATATGCAGG	PDZK1	ENSG00000174827	1.3349092616143543	[12]	[98]	9	hSpCas9	negative selection	12411134
145686500	145686523	1	-	28162770	OCIAML3	viability	GTGAAGGAAGGAGGCAGCTATGG	PDZK1	ENSG00000174827	-0.7178792984863316	[78]	[144]	-5	hSpCas9	negative selection	12411135
145687904	145687927	1	+	28162770	OCIAML3	viability	TCTCAACCACCCGGACCAGGTGG	PDZK1	ENSG00000174827	-0.2720795454368007	[77]	[194]	-2	hSpCas9	negative selection	12411136
145687981	145688004	1	+	28162770	OCIAML3	viability	TTGGACAGTTTACATTCTCGGGG	PDZK1	ENSG00000174827	-0.21860360048174932	[142]	[370]	-2	hSpCas9	negative selection	12411137
145687960	145687983	1	-	28162770	OCIAML3	viability	AAGCAAGAAGGGCAAAACTATGG	PDZK1	ENSG00000174827	1.0315968448943391	[34]	[215]	8	hSpCas9	negative selection	12411138
145687913	145687936	1	-	28162770	OCIAML3	viability	CACCGAGGGCCACCTGGTCCGGG	PDZK1	ENSG00000174827	1.0156169146312621	[28]	[176]	8	hSpCas9	negative selection	12411139