Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:375033
• Symbol:PEAR1
• Description:platelet endothelial aggregation receptor 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PEAR1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
156903933	156903956	1	-	26472758	Jiyoye	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	4.7994928042846325	[0]	[20]	9	hSpCas9	negative selection	118693
156913199	156913222	1	-	26472758	Jiyoye	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	5.8990284778355475	[0]	[44]	9	hSpCas9	negative selection	118694
156904756	156904779	1	-	26472758	Jiyoye	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-0.20875346989849597	[258]	[168]	-1	hSpCas9	negative selection	118695
156906772	156906795	1	-	26472758	Jiyoye	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	-0.4711460619058742	[124]	[67]	-3	hSpCas9	negative selection	118696
156907972	156907995	1	+	26472758	Jiyoye	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	0.2942813250999401	[278]	[257]	2	hSpCas9	negative selection	118697
156908308	156908331	1	-	26472758	Jiyoye	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	2.0592520780855663	[20]	[65]	8	hSpCas9	negative selection	118698
156908706	156908729	1	-	26472758	Jiyoye	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	-0.1855227679948881	[186]	[123]	-1	hSpCas9	negative selection	118699
156908720	156908743	1	+	26472758	Jiyoye	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	-0.7927621890028786	[84]	[36]	-5	hSpCas9	negative selection	118700
156908992	156909015	1	-	26472758	Jiyoye	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	0.039443597005386355	[159]	[123]	0	hSpCas9	negative selection	118701
156909783	156909806	1	-	26472758	Jiyoye	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	0.0032784398322299735	[85]	[64]	0	hSpCas9	negative selection	118702
156903933	156903956	1	-	26472758	KBM7	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-1.9389204111581295	[248,206]	[30,24]	-8	hSpCas9	negative selection	309811
156913199	156913222	1	-	26472758	KBM7	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	-0.4788162844093138	[159,156]	[2,98]	-4	hSpCas9	negative selection	309812
156904756	156904779	1	-	26472758	KBM7	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-1.377049537846059	[1024,690]	[124,177]	-7	hSpCas9	negative selection	309813
156906772	156906795	1	-	26472758	KBM7	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	0.2801262219352738	[260,89]	[91,98]	3	hSpCas9	negative selection	309814
156907972	156907995	1	+	26472758	KBM7	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	-0.22331541257335197	[1127,903]	[338,466]	-2	hSpCas9	negative selection	309815
156908308	156908331	1	-	26472758	KBM7	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	-0.7318790693121835	[229,231]	[79,52]	-6	hSpCas9	negative selection	309816
156908706	156908729	1	-	26472758	KBM7	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	0.6915480901591445	[528,551]	[444,384]	7	hSpCas9	negative selection	309817
156908720	156908743	1	+	26472758	KBM7	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	0.2723325572292719	[390,217]	[135,197]	3	hSpCas9	negative selection	309818
156908992	156909015	1	-	26472758	KBM7	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.020322972090235703	[942,606]	[445,269]	0	hSpCas9	negative selection	309819
156909783	156909806	1	-	26472758	KBM7	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	0.1006202928512605	[223,151]	[104,82]	1	hSpCas9	negative selection	309820
156903933	156903956	1	-	26472758	Raji	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-2.7752595139882414	[117]	[3]	-9	hSpCas9	negative selection	500929
156913199	156913222	1	-	26472758	Raji	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	-0.366547652958813	[99]	[17]	-3	hSpCas9	negative selection	500930
156904756	156904779	1	-	26472758	Raji	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-0.8486731170388035	[387]	[49]	-6	hSpCas9	negative selection	500931
156906772	156906795	1	-	26472758	Raji	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	0.7767382233851282	[82]	[32]	7	hSpCas9	negative selection	500932
156907972	156907995	1	+	26472758	Raji	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	0.4041949531918181	[393]	[120]	4	hSpCas9	negative selection	500933
156908308	156908331	1	-	26472758	Raji	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	-0.32871557943307395	[183]	[33]	-3	hSpCas9	negative selection	500934
156908706	156908729	1	-	26472758	Raji	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	-0.6815341384273282	[310]	[44]	-5	hSpCas9	negative selection	500935
156908720	156908743	1	+	26472758	Raji	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	0.4428038665890752	[148]	[46]	4	hSpCas9	negative selection	500936
156908992	156909015	1	-	26472758	Raji	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	0.32777360379889964	[308]	[89]	3	hSpCas9	negative selection	500937
156909783	156909806	1	-	26472758	Raji	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	0.1687840800377428	[137]	[35]	1	hSpCas9	negative selection	500938
156903933	156903956	1	-	26472758	K562	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-0.09144855817878916	[129]	[102]	0	hSpCas9	negative selection	692047
156913199	156913222	1	-	26472758	K562	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	-0.20809347703105963	[103]	[75]	-1	hSpCas9	negative selection	692048
156904756	156904779	1	-	26472758	K562	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-1.7573568972234046	[812]	[202]	-7	hSpCas9	negative selection	692049
156906772	156906795	1	-	26472758	K562	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	-0.03822023610685821	[162]	[133]	0	hSpCas9	negative selection	692050
156907972	156907995	1	+	26472758	K562	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	-0.13965242092918362	[1013]	[776]	-1	hSpCas9	negative selection	692051
156908308	156908331	1	-	26472758	K562	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	1.1564710283907442	[185]	[349]	8	hSpCas9	negative selection	692052
156908706	156908729	1	-	26472758	K562	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	-0.19269830508331537	[416]	[307]	-1	hSpCas9	negative selection	692053
156908720	156908743	1	+	26472758	K562	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	0.3493882872679893	[158]	[170]	2	hSpCas9	negative selection	692054
156908992	156909015	1	-	26472758	K562	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.22084196977304782	[681]	[493]	-1	hSpCas9	negative selection	692055
156909783	156909806	1	-	26472758	K562	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	0.19648425060274466	[152]	[147]	1	hSpCas9	negative selection	692056
156903968	156903991	1	-	26627737	DLD1	viability	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	-0.0014457226949944335	[418]	[69,203,122]	0	hSpCas9	negative selection	766637
156905373	156905396	1	+	26627737	DLD1	viability	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	-0.5562621838025273	[263]	[59,50,56]	-5	hSpCas9	negative selection	766638
156906304	156906327	1	-	26627737	DLD1	viability	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	-0.11359742415337393	[813]	[229,142,315]	-1	hSpCas9	negative selection	766639
156906789	156906812	1	-	26627737	DLD1	viability	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	-0.039914153654627804	[703]	[147,240,248]	0	hSpCas9	negative selection	766640
156907719	156907742	1	-	26627737	DLD1	viability	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	1.2089036464738914	[358]	[184,402,204]	9	hSpCas9	negative selection	766641
156907969	156907992	1	+	26627737	DLD1	viability	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.7662529234032681	[804]	[345,450,479]	7	hSpCas9	negative selection	766642
156903968	156903991	1	-	26627737	GBM cells	viability after 5 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.07846329521639839	[165]	[86,100]	1	hSpCas9	negative selection	848952
156905373	156905396	1	+	26627737	GBM cells	viability after 5 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	-0.040056691716754744	[161]	[62,105]	0	hSpCas9	negative selection	848953
156906304	156906327	1	-	26627737	GBM cells	viability after 5 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.08519878804864084	[340]	[192,194]	1	hSpCas9	negative selection	848954
156906789	156906812	1	-	26627737	GBM cells	viability after 5 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.1561601283580723	[332]	[202,194]	2	hSpCas9	negative selection	848955
156907719	156907742	1	-	26627737	GBM cells	viability after 5 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.2729106594721083	[284]	[142,109]	-4	hSpCas9	negative selection	848956
156907969	156907992	1	+	26627737	GBM cells	viability after 5 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.46250272481427457	[407]	[297,304]	7	hSpCas9	negative selection	848957
156903968	156903991	1	-	26627737	GBM cells	viability after 13 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.39491146903791496	[165]	[145,95]	5	hSpCas9	negative selection	931267
156905373	156905396	1	+	26627737	GBM cells	viability after 13 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	-0.030742217737246946	[161]	[106,68]	0	hSpCas9	negative selection	931268
156906304	156906327	1	-	26627737	GBM cells	viability after 13 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.3150717482047298	[340]	[238,222]	4	hSpCas9	negative selection	931269
156906789	156906812	1	-	26627737	GBM cells	viability after 13 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.4123531660601469	[332]	[181,287]	5	hSpCas9	negative selection	931270
156907719	156907742	1	-	26627737	GBM cells	viability after 13 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.17530248381571212	[284]	[158,118]	-2	hSpCas9	negative selection	931271
156907969	156907992	1	+	26627737	GBM cells	viability after 13 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.6343998438024121	[407]	[368,322]	7	hSpCas9	negative selection	931272
156903968	156903991	1	-	26627737	GBM cells	viability after 21 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.051230857081565495	[165]	[82,102]	0	hSpCas9	negative selection	1013582
156905373	156905396	1	+	26627737	GBM cells	viability after 21 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.059757455824613115	[161]	[97,85]	0	hSpCas9	negative selection	1013583
156906304	156906327	1	-	26627737	GBM cells	viability after 21 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.519294169223036	[340]	[264,265]	5	hSpCas9	negative selection	1013584
156906789	156906812	1	-	26627737	GBM cells	viability after 21 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.9724398345610075	[332]	[378,332]	8	hSpCas9	negative selection	1013585
156907719	156907742	1	-	26627737	GBM cells	viability after 21 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	0.44939840419633426	[284]	[224,198]	4	hSpCas9	negative selection	1013586
156907969	156907992	1	+	26627737	GBM cells	viability after 21 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.6937714019085173	[407]	[392,326]	7	hSpCas9	negative selection	1013587
156903968	156903991	1	-	26627737	RPE1	viability after 9 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	1.0812654995642847	[313]	[176,247]	6	hSpCas9	negative selection	1095897
156905373	156905396	1	+	26627737	RPE1	viability after 9 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.672360685150125	[322]	[175,141]	4	hSpCas9	negative selection	1095898
156906304	156906327	1	-	26627737	RPE1	viability after 9 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.5461586845479739	[1314]	[701,470]	4	hSpCas9	negative selection	1095899
156906789	156906812	1	-	26627737	RPE1	viability after 9 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	-0.2824937513738248	[1344]	[257,459]	-2	hSpCas9	negative selection	1095900
156907719	156907742	1	-	26627737	RPE1	viability after 9 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	2.1794214545070263	[238]	[303,383]	9	hSpCas9	negative selection	1095901
156907969	156907992	1	+	26627737	RPE1	viability after 9 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.1836025704887967	[1667]	[441,787]	1	hSpCas9	negative selection	1095902
156903968	156903991	1	-	26627737	RPE1	viability after 12 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.5956824440806848	[313]	[126,127]	4	hSpCas9	negative selection	1178212
156905373	156905396	1	+	26627737	RPE1	viability after 12 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.06261509573822455	[322]	[77,103]	0	hSpCas9	negative selection	1178213
156906304	156906327	1	-	26627737	RPE1	viability after 12 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.6520538400133246	[1314]	[764,332]	4	hSpCas9	negative selection	1178214
156906789	156906812	1	-	26627737	RPE1	viability after 12 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.4056558954622447	[1344]	[382,579]	2	hSpCas9	negative selection	1178215
156907719	156907742	1	-	26627737	RPE1	viability after 12 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	1.6933042909815388	[238]	[195,219]	8	hSpCas9	negative selection	1178216
156907969	156907992	1	+	26627737	RPE1	viability after 12 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.43531380052972546	[1667]	[468,750]	3	hSpCas9	negative selection	1178217
156903968	156903991	1	-	26627737	RPE1	viability after 15 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.881192974743396	[313]	[213,114]	5	hSpCas9	negative selection	1260527
156905373	156905396	1	+	26627737	RPE1	viability after 15 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.3149186528021892	[322]	[160,67]	2	hSpCas9	negative selection	1260528
156906304	156906327	1	-	26627737	RPE1	viability after 15 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.23020113845575707	[1314]	[557,318]	1	hSpCas9	negative selection	1260529
156906789	156906812	1	-	26627737	RPE1	viability after 15 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	-0.2362411236010824	[1344]	[125,512]	-1	hSpCas9	negative selection	1260530
156907719	156907742	1	-	26627737	RPE1	viability after 15 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	2.6956765775642366	[238]	[465,410]	9	hSpCas9	negative selection	1260531
156907969	156907992	1	+	26627737	RPE1	viability after 15 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.12497406861909588	[1667]	[399,624]	0	hSpCas9	negative selection	1260532
156903968	156903991	1	-	26627737	RPE1	viability after 18 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.33970601966416136	[313]	[84,130]	2	hSpCas9	negative selection	1342842
156905373	156905396	1	+	26627737	RPE1	viability after 18 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.625918182348802	[322]	[134,133]	4	hSpCas9	negative selection	1342843
156906304	156906327	1	-	26627737	RPE1	viability after 18 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.742576157068391	[1314]	[790,382]	4	hSpCas9	negative selection	1342844
156906789	156906812	1	-	26627737	RPE1	viability after 18 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.29209435138576545	[1344]	[354,539]	1	hSpCas9	negative selection	1342845
156907719	156907742	1	-	26627737	RPE1	viability after 18 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	2.0710766395686138	[238]	[227,316]	8	hSpCas9	negative selection	1342846
156907969	156907992	1	+	26627737	RPE1	viability after 18 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.16392615053921422	[1667]	[352,665]	1	hSpCas9	negative selection	1342847
156903968	156903991	1	-	26627737	HeLa	viability after 8 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	-0.162689784204595	[251]	[21,139,113]	-1	hSpCas9	negative selection	1425157
156905373	156905396	1	+	26627737	HeLa	viability after 8 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	2.497526573894441	[65]	[256,96,153]	9	hSpCas9	negative selection	1425158
156906304	156906327	1	-	26627737	HeLa	viability after 8 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.12540535961866495	[604]	[285,417,165]	1	hSpCas9	negative selection	1425159
156906789	156906812	1	-	26627737	HeLa	viability after 8 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.06331537299958567	[890]	[714,318,259]	0	hSpCas9	negative selection	1425160
156907719	156907742	1	-	26627737	HeLa	viability after 8 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.46706258499701975	[401]	[227,121,56]	-4	hSpCas9	negative selection	1425161
156907969	156907992	1	+	26627737	HeLa	viability after 8 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.22883906731365322	[694]	[550,445,125]	2	hSpCas9	negative selection	1425162
156903968	156903991	1	-	26627737	HeLa	viability after 12 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.3924890911095174	[251]	[140,53,223]	3	hSpCas9	negative selection	1507472
156905373	156905396	1	+	26627737	HeLa	viability after 12 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	1.2356315319191178	[65]	[15,132,34]	8	hSpCas9	negative selection	1507473
156906304	156906327	1	-	26627737	HeLa	viability after 12 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	-0.2698993157063684	[604]	[219,173,231]	-2	hSpCas9	negative selection	1507474
156906789	156906812	1	-	26627737	HeLa	viability after 12 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	-0.6659812794473873	[890]	[199,281,207]	-5	hSpCas9	negative selection	1507475
156907719	156907742	1	-	26627737	HeLa	viability after 12 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.0771168536558875	[401]	[103,165,199]	0	hSpCas9	negative selection	1507476
156907969	156907992	1	+	26627737	HeLa	viability after 12 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.20275510881290504	[694]	[324,476,173]	1	hSpCas9	negative selection	1507477
156903968	156903991	1	-	26627737	HeLa	viability after 15 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	-0.3791414363508644	[251]	[50,82,104]	-3	hSpCas9	negative selection	1589787
156905373	156905396	1	+	26627737	HeLa	viability after 15 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	2.266878596117661	[65]	[102,98,190]	9	hSpCas9	negative selection	1589788
156906304	156906327	1	-	26627737	HeLa	viability after 15 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	-0.5357405957875743	[604]	[255,137,109]	-5	hSpCas9	negative selection	1589789
156906789	156906812	1	-	26627737	HeLa	viability after 15 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.31693638679367386	[890]	[429,350,584]	2	hSpCas9	negative selection	1589790
156907719	156907742	1	-	26627737	HeLa	viability after 15 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.6150595579176547	[401]	[89,96,135]	-5	hSpCas9	negative selection	1589791
156907969	156907992	1	+	26627737	HeLa	viability after 15 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.45648762958349776	[694]	[492,322,343]	4	hSpCas9	negative selection	1589792
156903968	156903991	1	-	26627737	HeLa	viability after 18 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	-0.33470270671214153	[251]	[33,74,104]	-3	hSpCas9	negative selection	1672102
156905373	156905396	1	+	26627737	HeLa	viability after 18 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	2.2583113064671476	[65]	[69,78,190]	9	hSpCas9	negative selection	1672103
156906304	156906327	1	-	26627737	HeLa	viability after 18 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	-0.5037143067553916	[604]	[176,116,109]	-4	hSpCas9	negative selection	1672104
156906789	156906812	1	-	26627737	HeLa	viability after 18 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.32148315299984564	[890]	[294,285,584]	2	hSpCas9	negative selection	1672105
156907719	156907742	1	-	26627737	HeLa	viability after 18 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.6307056362782851	[401]	[51,87,135]	-5	hSpCas9	negative selection	1672106
156907969	156907992	1	+	26627737	HeLa	viability after 18 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.4778227660959967	[694]	[335,274,343]	4	hSpCas9	negative selection	1672107
156903968	156903991	1	-	26627737	HCT116	viability after 6 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	1.0311361823832514	[392]	[298,30]	5	hSpCas9	negative selection	1754417
156905373	156905396	1	+	26627737	HCT116	viability after 6 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	-0.8360097217363307	[298]	[35,20]	-5	hSpCas9	negative selection	1754418
156906304	156906327	1	-	26627737	HCT116	viability after 6 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	1.1020930400689029	[479]	[248,113]	6	hSpCas9	negative selection	1754419
156906789	156906812	1	-	26627737	HCT116	viability after 6 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.037286958953365756	[1070]	[175,170]	0	hSpCas9	negative selection	1754420
156907719	156907742	1	-	26627737	HCT116	viability after 6 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-2.022946206889322	[895]	[82,7]	-8	hSpCas9	negative selection	1754421
156907969	156907992	1	+	26627737	HCT116	viability after 6 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	1.1328713648338156	[750]	[566,88]	6	hSpCas9	negative selection	1754422
156903968	156903991	1	-	26627737	HCT116	viability after 8 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	-0.4995519308327959	[275]	[122,92,106]	-5	hSpCas9	negative selection	1836732
156905373	156905396	1	+	26627737	HCT116	viability after 8 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	1.1102029477321795	[82]	[85,113,95]	8	hSpCas9	negative selection	1836733
156906304	156906327	1	-	26627737	HCT116	viability after 8 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	-0.0291882308189928	[357]	[197,185,195]	0	hSpCas9	negative selection	1836734
156906789	156906812	1	-	26627737	HCT116	viability after 8 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	-0.18780032118755963	[722]	[389,308,350]	-2	hSpCas9	negative selection	1836735
156907719	156907742	1	-	26627737	HCT116	viability after 8 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.25475984766122933	[310]	[120,125,182]	-3	hSpCas9	negative selection	1836736
156907969	156907992	1	+	26627737	HCT116	viability after 8 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	-0.04018306458915788	[806]	[445,531,320]	0	hSpCas9	negative selection	1836737
156903968	156903991	1	-	26627737	HCT116	viability after 9 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.7514903578242674	[392]	[155,192]	5	hSpCas9	negative selection	1919047
156905373	156905396	1	+	26627737	HCT116	viability after 9 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	-0.646586520873141	[298]	[112,1]	-4	hSpCas9	negative selection	1919048
156906304	156906327	1	-	26627737	HCT116	viability after 9 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.4055009660627652	[479]	[295,69]	3	hSpCas9	negative selection	1919049
156906789	156906812	1	-	26627737	HCT116	viability after 9 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.44447468155680103	[1070]	[544,265]	3	hSpCas9	negative selection	1919050
156907719	156907742	1	-	26627737	HCT116	viability after 9 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.3958564860779411	[895]	[211,157]	-3	hSpCas9	negative selection	1919051
156907969	156907992	1	+	26627737	HCT116	viability after 9 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.8556450932792281	[750]	[344,376]	6	hSpCas9	negative selection	1919052
156903968	156903991	1	-	26627737	HCT116	viability after 12 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	-0.31023925633624777	[275]	[120,133,95]	-3	hSpCas9	negative selection	2001362
156905373	156905396	1	+	26627737	HCT116	viability after 12 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.6556809848597316	[82]	[70,70,63]	6	hSpCas9	negative selection	2001363
156906304	156906327	1	-	26627737	HCT116	viability after 12 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	-0.029951984085272443	[357]	[130,204,221]	0	hSpCas9	negative selection	2001364
156906789	156906812	1	-	26627737	HCT116	viability after 12 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	-0.3868559582896104	[722]	[411,203,242]	-4	hSpCas9	negative selection	2001365
156907719	156907742	1	-	26627737	HCT116	viability after 12 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.09253619255385791	[310]	[168,174,114]	-1	hSpCas9	negative selection	2001366
156907969	156907992	1	+	26627737	HCT116	viability after 12 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.03837892926341846	[806]	[360,346,602]	0	hSpCas9	negative selection	2001367
156903968	156903991	1	-	26627737	HCT116	viability after 15 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.2411338964173732	[275]	[223,114,226]	2	hSpCas9	negative selection	2083677
156905373	156905396	1	+	26627737	HCT116	viability after 15 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	-0.006675460243317444	[82]	[37,39,62]	0	hSpCas9	negative selection	2083678
156906304	156906327	1	-	26627737	HCT116	viability after 15 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	-0.15798567469500702	[357]	[111,162,267]	-2	hSpCas9	negative selection	2083679
156906789	156906812	1	-	26627737	HCT116	viability after 15 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.08421250288042725	[722]	[725,412,218]	0	hSpCas9	negative selection	2083680
156907719	156907742	1	-	26627737	HCT116	viability after 15 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.43170164610355144	[310]	[158,68,171]	-4	hSpCas9	negative selection	2083681
156907969	156907992	1	+	26627737	HCT116	viability after 15 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	-0.06028577509218169	[806]	[480,419,436]	0	hSpCas9	negative selection	2083682
156903968	156903991	1	-	26627737	HCT116	viability after 18 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.05110881541408162	[275]	[146,80,192]	0	hSpCas9	negative selection	2165992
156905373	156905396	1	+	26627737	HCT116	viability after 18 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.28883894490656803	[82]	[71,22,53]	2	hSpCas9	negative selection	2165993
156906304	156906327	1	-	26627737	HCT116	viability after 18 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	-0.031104034980788953	[357]	[99,104,313]	0	hSpCas9	negative selection	2165994
156906789	156906812	1	-	26627737	HCT116	viability after 18 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	-0.134989690568043	[722]	[221,305,432]	-1	hSpCas9	negative selection	2165995
156907719	156907742	1	-	26627737	HCT116	viability after 18 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.5013505891647524	[310]	[207,69,39]	-4	hSpCas9	negative selection	2165996
156907969	156907992	1	+	26627737	HCT116	viability after 18 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.030399819240652937	[806]	[429,302,471]	0	hSpCas9	negative selection	2165997
156895820	156895843	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCAAAATGCTGGGATTACCGG	PEAR1	ENSG00000187800	0.20161513672590614	[46,60]	[10,15]	1	dCas9-VP64	positive selection	2475401
156895820	156895843	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCAAAATGCTGGGATTACCGG	PEAR1	ENSG00000187800	-0.42275240861415275	[53,301]	[32,50]	-4	dCas9-VP64	positive selection	2570656
156908117	156908140	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTAGGTGCCCAGGTGCCGGGAGG	PEAR1	ENSG00000187800	0.07777338105648399	[3,3]	[1,4]	1	hSpCas9	positive selection	3010643
156906825	156906848	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCAGTCTGGGGATCGCAGGG	PEAR1	ENSG00000187800	-0.17719915432753972	[2,3]	[2,1]	-3	hSpCas9	positive selection	3010644
156905345	156905368	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCCGTCTTCACCACCTGACGG	PEAR1	ENSG00000187800	-0.09022129470931206	[3,3]	[3,1]	-1	hSpCas9	positive selection	3010645
156907681	156907704	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGTCTTCCAAACCCCACAGGG	PEAR1	ENSG00000187800	0.3160659437382651	[4,4]	[5,4]	6	hSpCas9	positive selection	3010646
156908117	156908140	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTAGGTGCCCAGGTGCCGGGAGG	PEAR1	ENSG00000187800	0.49504795786528377	[3,3]	[4,3]	8	hSpCas9	positive selection	3078501
156906825	156906848	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCAGTCTGGGGATCGCAGGG	PEAR1	ENSG00000187800	0.2117297760349464	[2,2]	[3,1]	4	hSpCas9	positive selection	3078502
156905345	156905368	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCCGTCTTCACCACCTGACGG	PEAR1	ENSG00000187800	-0.2077196837141295	[3,3]	[3,0]	-3	hSpCas9	positive selection	3078503
156907681	156907704	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGTCTTCCAAACCCCACAGGG	PEAR1	ENSG00000187800	0.17649227656402733	[4,4]	[4,2]	3	hSpCas9	positive selection	3078504
156906696	156906719		+	24336571	A375	resistance to PLX after 7 days	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.08472383922849946	[4,5]	[4,5]	-3	hSpCas9	positive selection	3134891
156906809	156906832		-	24336571	A375	resistance to PLX after 7 days	CGCAGGGTGCCCCATGGCACTGG	PEAR1	ENSG00000187800	-0.3205467010190986	[11,12]	[8,9]	-8	hSpCas9	positive selection	3134892
156905338	156905361		-	24336571	A375	resistance to PLX after 7 days	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	-0.22103368435777504	[24,20]	[21,16]	-6	hSpCas9	positive selection	3134893
156906852	156906875		+	24336571	A375	resistance to PLX after 7 days	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.5545478531608826	[14,17]	[9,11]	-9	hSpCas9	positive selection	3134895
156906696	156906719		+	24336571	A375	resistance to PLX after 14 days	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.021016705692235016	[5,4]	[1,1]	0	hSpCas9	positive selection	3192684
156906809	156906832		-	24336571	A375	resistance to PLX after 14 days	CGCAGGGTGCCCCATGGCACTGG	PEAR1	ENSG00000187800	-0.36179776130778346	[8,10]	[4,1]	-4	hSpCas9	positive selection	3192685
156905338	156905361		-	24336571	A375	resistance to PLX after 14 days	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	-0.6425293513393061	[24,27]	[6,7]	-7	hSpCas9	positive selection	3192686
156906852	156906875		+	24336571	A375	resistance to PLX after 14 days	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.18519202113116076	[6,18]	[4,4]	-2	hSpCas9	positive selection	3192688
156906696	156906719		+	24336571	A375	viability after 7 days	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.21939409524574172	[6]	[4,5]	-3	hSpCas9	negative selection	3250477
156906809	156906832		-	24336571	A375	viability after 7 days	CGCAGGGTGCCCCATGGCACTGG	PEAR1	ENSG00000187800	-0.08606416594873484	[13]	[11,12]	-1	hSpCas9	negative selection	3250478
156905338	156905361		-	24336571	A375	viability after 7 days	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.6132343363746136	[15]	[24,20]	8	hSpCas9	negative selection	3250479
156906852	156906875		+	24336571	A375	viability after 7 days	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.5589649514546586	[10]	[14,17]	8	hSpCas9	negative selection	3250481
156906696	156906719		+	24336571	A375	viability after 14 days	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.24428192859845466	[6]	[5,4]	-3	hSpCas9	negative selection	3308270
156906809	156906832		-	24336571	A375	viability after 14 days	CGCAGGGTGCCCCATGGCACTGG	PEAR1	ENSG00000187800	-0.34390853867608817	[13]	[8,10]	-4	hSpCas9	negative selection	3308271
156905338	156905361		-	24336571	A375	viability after 14 days	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.8167817056217912	[15]	[24,27]	8	hSpCas9	negative selection	3308272
156906852	156906875		+	24336571	A375	viability after 14 days	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.24552946451095517	[10]	[6,18]	3	hSpCas9	negative selection	3308274
156906852	156906875	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.6851882938934047	[245,245]	[0,0]	-5	hSpCas9	positive selection	3385325
156907679	156907702	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	1.0874012100035229	[71,71]	[0,0]	5	hSpCas9	positive selection	3385326
156907656	156907679	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	-0.44311350669525723	[207,207]	[0,0]	-3	hSpCas9	positive selection	3385327
156908116	156908139	1	+	26780180	HT29	viability (Avana library 4 designs)	CTAGGTGCCCAGGTGCCGGGAGG	PEAR1	ENSG00000187800	1.9758388543537	[]	[]	7	hSpCas9	negative selection	3448702
156906825	156906848	1	-	26780180	HT29	viability (Avana library 4 designs)	GCTCCAGTCTGGGGATCGCAGGG	PEAR1	ENSG00000187800	1.86041360413371	[]	[]	7	hSpCas9	negative selection	3448703
156905345	156905368	1	-	26780180	HT29	viability (Avana library 4 designs)	GGTCCGTCTTCACCACCTGACGG	PEAR1	ENSG00000187800	1.42075630009935	[]	[]	5	hSpCas9	negative selection	3448704
156907680	156907703	1	+	26780180	HT29	viability (Avana library 4 designs)	GGTGTCTTCCAAACCCCACAGGG	PEAR1	ENSG00000187800	0.544606720167076	[]	[]	2	hSpCas9	negative selection	3448705
156907680	156907703	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGTCTTCCAAACCCCACAGGG	PEAR1	ENSG00000187800	-1.21945803895723	[]	[]	-1	hSpCas9	negative selection	3543109
156906825	156906848	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCAGTCTGGGGATCGCAGGG	PEAR1	ENSG00000187800	5.88003222165503	[]	[]	9	hSpCas9	negative selection	3543110
156905345	156905368	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCCGTCTTCACCACCTGACGG	PEAR1	ENSG00000187800	-6.25709650330309	[]	[]	-6	hSpCas9	negative selection	3543111
156908116	156908139	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGGTGCCCAGGTGCCGGGAGG	PEAR1	ENSG00000187800	3.26517326015638	[]	[]	5	hSpCas9	negative selection	3543112
156906800	156906823	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCCGCTGCCAGTGCCATGGGG	PEAR1	ENSG00000187800	2.36753235940577	[]	[]	3	hSpCas9	negative selection	3543113
156905391	156905414	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATGGCTTCTATGAGAGCAGGGG	PEAR1	ENSG00000187800	-0.373568430939409	[]	[]	0	hSpCas9	negative selection	3543114
156907680	156907703	1	+	26780180	A375	viability (Avana lentiGuide)	GGTGTCTTCCAAACCCCACAGGG	PEAR1	ENSG00000187800	0.757634761293015	[]	[]	0	hSpCas9	negative selection	3651768
156906825	156906848	1	-	26780180	A375	viability (Avana lentiGuide)	GCTCCAGTCTGGGGATCGCAGGG	PEAR1	ENSG00000187800	1.83408342138038	[]	[]	2	hSpCas9	negative selection	3651769
156905345	156905368	1	-	26780180	A375	viability (Avana lentiGuide)	GGTCCGTCTTCACCACCTGACGG	PEAR1	ENSG00000187800	19.0841737863921	[]	[]	8	hSpCas9	negative selection	3651770
156908116	156908139	1	+	26780180	A375	viability (Avana lentiGuide)	CTAGGTGCCCAGGTGCCGGGAGG	PEAR1	ENSG00000187800	-0.998490373173802	[]	[]	-1	hSpCas9	negative selection	3651771
156906800	156906823	1	+	26780180	A375	viability (Avana lentiGuide)	GTTCCGCTGCCAGTGCCATGGGG	PEAR1	ENSG00000187800	1.55165731496384	[]	[]	1	hSpCas9	negative selection	3651772
156905391	156905414	1	+	26780180	A375	viability (Avana lentiGuide)	CATGGCTTCTATGAGAGCAGGGG	PEAR1	ENSG00000187800	7.0276252374677	[]	[]	5	hSpCas9	negative selection	3651773
156907680	156907703	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGTCTTCCAAACCCCACAGGG	PEAR1	ENSG00000187800	-0.19965728303955063	[5]	[6,3]	-3	hSpCas9	positive selection	3760427
156906825	156906848	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCAGTCTGGGGATCGCAGGG	PEAR1	ENSG00000187800	0.23556769305790035	[4]	[5,4]	6	hSpCas9	positive selection	3760428
156905345	156905368	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCCGTCTTCACCACCTGACGG	PEAR1	ENSG00000187800	-0.3344783076794354	[4]	[2,4]	-5	hSpCas9	positive selection	3760429
156908116	156908139	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGGTGCCCAGGTGCCGGGAGG	PEAR1	ENSG00000187800	0.26021392131234083	[5]	[6,6]	7	hSpCas9	positive selection	3760430
156906800	156906823	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCCGCTGCCAGTGCCATGGGG	PEAR1	ENSG00000187800	0.25342971950836723	[5]	[7,6]	7	hSpCas9	positive selection	3760431
156905391	156905414	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGGCTTCTATGAGAGCAGGGG	PEAR1	ENSG00000187800	-0.33275562035287864	[4]	[3,3]	-5	hSpCas9	positive selection	3760432
156907680	156907703	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGTCTTCCAAACCCCACAGGG	PEAR1	ENSG00000187800	-0.136040220241039	[6]	[3,4]	-2	hSpCas9	positive selection	3869034
156906825	156906848	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCAGTCTGGGGATCGCAGGG	PEAR1	ENSG00000187800	-0.8716157790682246	[4]	[2,0]	-8	hSpCas9	positive selection	3869035
156905345	156905368	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCCGTCTTCACCACCTGACGG	PEAR1	ENSG00000187800	-0.01947691964593577	[5]	[4,3]	0	hSpCas9	positive selection	3869036
156908116	156908139	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGGTGCCCAGGTGCCGGGAGG	PEAR1	ENSG00000187800	0.3193288083181328	[5]	[5,6]	8	hSpCas9	positive selection	3869037
156906800	156906823	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCCGCTGCCAGTGCCATGGGG	PEAR1	ENSG00000187800	0.2682271309037185	[6]	[6,6]	7	hSpCas9	positive selection	3869038
156905391	156905414	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGGCTTCTATGAGAGCAGGGG	PEAR1	ENSG00000187800	-0.8621914336519019	[4]	[1,1]	-8	hSpCas9	positive selection	3869039
156907656	156907679	1	+	26780180	A375	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.732187437805916	[]	[]	2	hSpCas9	negative selection	3979804
156906696	156906719	1	+	26780180	A375	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	1.31096150945694	[]	[]	7	hSpCas9	negative selection	3979805
156907679	156907702	1	+	26780180	A375	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	1.15380982668628	[]	[]	6	hSpCas9	negative selection	3979806
156905338	156905361	1	-	26780180	A375	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	1.1724620776208	[]	[]	6	hSpCas9	negative selection	3979807
156905314	156905337	1	+	26780180	A375	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.986742584510526	[]	[]	4	hSpCas9	negative selection	3979808
156906852	156906875	1	+	26780180	A375	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	1.37428953323585	[]	[]	7	hSpCas9	negative selection	3979809
156907656	156907679	1	+	26780180	HT29	viability (GeCKOv2 library)	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.6126737033795	[]	[]	2	hSpCas9	negative selection	4087770
156906696	156906719	1	+	26780180	HT29	viability (GeCKOv2 library)	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	1.11332271117491	[]	[]	5	hSpCas9	negative selection	4087771
156907679	156907702	1	+	26780180	HT29	viability (GeCKOv2 library)	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	1.28695144536549	[]	[]	6	hSpCas9	negative selection	4087772
156905338	156905361	1	-	26780180	HT29	viability (GeCKOv2 library)	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	-0.0716102297231416	[]	[]	-2	hSpCas9	negative selection	4087773
156905314	156905337	1	+	26780180	HT29	viability (GeCKOv2 library)	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	1.56348263506041	[]	[]	8	hSpCas9	negative selection	4087774
156906852	156906875	1	+	26780180	HT29	viability (GeCKOv2 library)	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	2.04597099028458	[]	[]	9	hSpCas9	negative selection	4087775
156906696	156906719	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.22560675565413327	[3]	[2,0]	-5	hSpCas9	positive selection	4159797
156906809	156906832	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCAGGGTGCCCCATGGCACTGG	PEAR1	ENSG00000187800	-0.5565282817835174	[3]	[1,1]	-9	hSpCas9	positive selection	4159798
156905338	156905361	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	-0.07248586374964672	[4]	[2,2]	-2	hSpCas9	positive selection	4159799
156906852	156906875	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.20175661033332956	[3]	[1,2]	-5	hSpCas9	positive selection	4159801
156906696	156906719	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.03790458367044394	[2]	[2,0,0,0]	0	hSpCas9	positive selection	4223819
156906809	156906832	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCAGGGTGCCCCATGGCACTGG	PEAR1	ENSG00000187800	-0.3892316165395058	[3]	[1,0,1,0]	-5	hSpCas9	positive selection	4223820
156905338	156905361	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	1.173727863897847	[3]	[0,4,4,3]	8	hSpCas9	positive selection	4223821
156906852	156906875	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.22667860345765894	[2]	[1,1,0,0]	1	hSpCas9	positive selection	4223823
156905314	156905337	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	-0.47405073012168386	[3]	[2,0]	-8	hSpCas9	positive selection	4289658
156905338	156905361	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.6365372978860174	[2]	[3,3]	9	hSpCas9	positive selection	4289659
156906696	156906719	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	0.16252875285274437	[2]	[2,1]	3	hSpCas9	positive selection	4289660
156906852	156906875	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.6259986562851104	[3]	[1,0]	-8	hSpCas9	positive selection	4353910
156907679	156907702	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.42075495187110057	[2]	[2,1]	8	hSpCas9	positive selection	4353911
156907656	156907679	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.1196567838743193	[2]	[2,1]	2	hSpCas9	positive selection	4353912
156905331	156905353	1	+	27760321	OCIAML3	viability	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.6125741511592738	[717,552]	[303,346]	-6	hSpCas9	negative selection	4426909
156908024	156908046	1	+	27760321	OCIAML3	viability	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-0.5744029428550972	[538,491]	[254,290]	-5	hSpCas9	negative selection	4426910
156908214	156908236	1	-	27760321	OCIAML3	viability	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	-0.3391465767627758	[637,504]	[229,508]	-4	hSpCas9	negative selection	4426911
156908818	156908840	1	-	27760321	OCIAML3	viability	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	-0.3870411667990295	[845,671]	[405,509]	-4	hSpCas9	negative selection	4426912
156908995	156909017	1	+	27760321	OCIAML3	viability	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	0.22044904174140578	[1201,1021]	[863,1199]	2	hSpCas9	negative selection	4426913
156905331	156905353	1	+	27760321	OCIAML2	viability	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.6948513157326431	[717,552]	[319,308]	-6	hSpCas9	negative selection	4510372
156908024	156908046	1	+	27760321	OCIAML2	viability	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-0.10153449055114941	[538,491]	[356,429]	-1	hSpCas9	negative selection	4510373
156908214	156908236	1	-	27760321	OCIAML2	viability	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	-0.2063228492116248	[637,504]	[326,491]	-3	hSpCas9	negative selection	4510374
156908818	156908840	1	-	27760321	OCIAML2	viability	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	0.1133386177994411	[845,671]	[455,928]	1	hSpCas9	negative selection	4510375
156908995	156909017	1	+	27760321	OCIAML2	viability	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	0.039683817225588225	[1201,1021]	[820,1053]	0	hSpCas9	negative selection	4510376
156905331	156905353	1	+	27760321	MV411	viability	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.838492155880629	[717,552]	[223,245]	-5	hSpCas9	negative selection	4593835
156908024	156908046	1	+	27760321	MV411	viability	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-0.2307767198847833	[538,491]	[240,362]	-2	hSpCas9	negative selection	4593836
156908214	156908236	1	-	27760321	MV411	viability	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	-0.5929075508612249	[637,504]	[96,475]	-4	hSpCas9	negative selection	4593837
156908818	156908840	1	-	27760321	MV411	viability	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	0.07608994524123802	[845,671]	[471,603]	0	hSpCas9	negative selection	4593838
156908995	156909017	1	+	27760321	MV411	viability	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	-0.012675729314327144	[1201,1021]	[660,820]	0	hSpCas9	negative selection	4593839
156905331	156905353	1	+	27760321	HL60	viability	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.6796603211410743	[717,552]	[311,331]	-6	hSpCas9	negative selection	4677298
156908024	156908046	1	+	27760321	HL60	viability	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-0.5955981280378082	[538,491]	[279,276]	-6	hSpCas9	negative selection	4677299
156908214	156908236	1	-	27760321	HL60	viability	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	-0.7248947224301518	[637,504]	[286,273]	-6	hSpCas9	negative selection	4677300
156908818	156908840	1	-	27760321	HL60	viability	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	-0.2473790398161665	[845,671]	[439,602]	-3	hSpCas9	negative selection	4677301
156908995	156909017	1	+	27760321	HL60	viability	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	-0.04228344876385148	[1201,1021]	[950,802]	0	hSpCas9	negative selection	4677302
156905331	156905353	1	+	27760321	HT1080	viability	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.8686849028037629	[552,431]	[116,96]	-4	hSpCas9	negative selection	4760761
156908024	156908046	1	+	27760321	HT1080	viability	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-1.0794629009633985	[491,383]	[83,80]	-4	hSpCas9	negative selection	4760762
156908214	156908236	1	-	27760321	HT1080	viability	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	0.04889810397835387	[504,393]	[126,248]	0	hSpCas9	negative selection	4760763
156908818	156908840	1	-	27760321	HT1080	viability	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	0.2636383898236262	[671,524]	[301,268]	1	hSpCas9	negative selection	4760764
156908995	156909017	1	+	27760321	HT1080	viability	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	0.40037065821881535	[1021,797]	[593,351]	2	hSpCas9	negative selection	4760765
156905331	156905353	1	+	27760321	HT29	viability after 7 days	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.4747939130062368	[552,431]	[502,347,519]	-6	hSpCas9	negative selection	4844224
156908024	156908046	1	+	27760321	HT29	viability after 7 days	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-0.45860680350275507	[491,383]	[613,427,221]	-6	hSpCas9	negative selection	4844225
156908214	156908236	1	-	27760321	HT29	viability after 7 days	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	0.20774549464781256	[504,393]	[951,616,478]	3	hSpCas9	negative selection	4844226
156908818	156908840	1	-	27760321	HT29	viability after 7 days	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	0.08328314636841916	[671,524]	[939,597,920]	1	hSpCas9	negative selection	4844227
156908995	156909017	1	+	27760321	HT29	viability after 7 days	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	0.04894025938645585	[1021,797]	[1092,1381,1139]	0	hSpCas9	negative selection	4844228
156905331	156905353	1	+	27760321	HT29	viability after 25 days	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.5218408695339282	[552,431]	[374,267,549]	-5	hSpCas9	negative selection	4927687
156908024	156908046	1	+	27760321	HT29	viability after 25 days	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-0.12868055587190502	[491,383]	[665,267,421]	-1	hSpCas9	negative selection	4927688
156908214	156908236	1	-	27760321	HT29	viability after 25 days	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	0.3816899115974124	[504,393]	[648,698,658]	4	hSpCas9	negative selection	4927689
156908818	156908840	1	-	27760321	HT29	viability after 25 days	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	0.4693012996451883	[671,524]	[1007,877,949]	5	hSpCas9	negative selection	4927690
156908995	156909017	1	+	27760321	HT29	viability after 25 days	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	0.4705392356418281	[1021,797]	[1451,1084,1822]	5	hSpCas9	negative selection	4927691
156905331	156905353	1	+	27760321	HT29	viability after 22 days	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.45713009231582996	[552,431]	[302,454,489]	-4	hSpCas9	negative selection	5011150
156908024	156908046	1	+	27760321	HT29	viability after 22 days	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-0.4122623988145188	[491,383]	[418,280,440]	-4	hSpCas9	negative selection	5011151
156908214	156908236	1	-	27760321	HT29	viability after 22 days	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	0.21087919243174313	[504,393]	[804,468,523]	2	hSpCas9	negative selection	5011152
156908818	156908840	1	-	27760321	HT29	viability after 22 days	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	0.6769845342098376	[671,524]	[1266,879,1167]	7	hSpCas9	negative selection	5011153
156908995	156909017	1	+	27760321	HT29	viability after 22 days	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	0.6587990057255091	[1021,797]	[1804,1386,1787]	7	hSpCas9	negative selection	5011154
156905331	156905353	1	+	27760321	HT29	viability after 19 days	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	0.25881166491358804	[552,431]	[743,642,642]	2	hSpCas9	negative selection	5094613
156908024	156908046	1	+	27760321	HT29	viability after 19 days	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-0.002519389851879106	[491,383]	[740,362,423]	0	hSpCas9	negative selection	5094614
156908214	156908236	1	-	27760321	HT29	viability after 19 days	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	0.25604792936042897	[504,393]	[487,722,616]	2	hSpCas9	negative selection	5094615
156908818	156908840	1	-	27760321	HT29	viability after 19 days	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	0.3218236384333867	[671,524]	[851,754,954]	3	hSpCas9	negative selection	5094616
156908995	156909017	1	+	27760321	HT29	viability after 19 days	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	0.2785256458206433	[1021,797]	[1455,1070,1278]	2	hSpCas9	negative selection	5094617
156905331	156905353	1	+	27760321	HT29	viability after 16 days	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.9970785146831023	[552,431]	[319,250,261]	-7	hSpCas9	negative selection	5178076
156908024	156908046	1	+	27760321	HT29	viability after 16 days	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-0.16768898043686148	[491,383]	[654,182,497]	-2	hSpCas9	negative selection	5178077
156908214	156908236	1	-	27760321	HT29	viability after 16 days	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	-0.15308007116374284	[504,393]	[605,499,263]	-2	hSpCas9	negative selection	5178078
156908818	156908840	1	-	27760321	HT29	viability after 16 days	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	0.5514656244519186	[671,524]	[859,1234,830]	6	hSpCas9	negative selection	5178079
156908995	156909017	1	+	27760321	HT29	viability after 16 days	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	0.42695388210768415	[1021,797]	[1489,1160,1471]	5	hSpCas9	negative selection	5178080
156905331	156905353	1	+	27760321	HT29	viability after 13 days	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.2222255609227983	[552,431]	[707,375,390]	-3	hSpCas9	negative selection	5261539
156908024	156908046	1	+	27760321	HT29	viability after 13 days	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-0.6638484052997016	[491,383]	[287,281,387]	-6	hSpCas9	negative selection	5261540
156908214	156908236	1	-	27760321	HT29	viability after 13 days	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	-0.09364803329752838	[504,393]	[538,474,453]	-1	hSpCas9	negative selection	5261541
156908818	156908840	1	-	27760321	HT29	viability after 13 days	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	0.6508145295745861	[671,524]	[1012,1191,1066]	8	hSpCas9	negative selection	5261542
156908995	156909017	1	+	27760321	HT29	viability after 13 days	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	0.1872645232485377	[1021,797]	[1304,1120,1180]	2	hSpCas9	negative selection	5261543
156905331	156905353	1	+	27760321	HT29	viability after 10 days	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.2981237838564653	[552,431]	[444,597,460]	-4	hSpCas9	negative selection	5345002
156908024	156908046	1	+	27760321	HT29	viability after 10 days	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	-0.06644861286476544	[491,383]	[812,478,278]	-1	hSpCas9	negative selection	5345003
156908214	156908236	1	-	27760321	HT29	viability after 10 days	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	-0.4559344487456068	[504,393]	[336,433,455]	-5	hSpCas9	negative selection	5345004
156908818	156908840	1	-	27760321	HT29	viability after 10 days	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	0.39172431267128094	[671,524]	[1068,1017,857]	5	hSpCas9	negative selection	5345005
156908995	156909017	1	+	27760321	HT29	viability after 10 days	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	0.011282208730376775	[1021,797]	[1252,911,1260]	0	hSpCas9	negative selection	5345006
156905331	156905353	1	+	27760321	MOLM13	viability	TACCGGACCGTGTACCGTCAGG	PEAR1	ENSG00000187800	-0.20915292512349853	[717,552]	[201,397]	-1	hSpCas9	negative selection	5428465
156908024	156908046	1	+	27760321	MOLM13	viability	GCTGCGCTCCGGGTTACACTGG	PEAR1	ENSG00000187800	0.6195576891604253	[538,491]	[827,121]	4	hSpCas9	negative selection	5428466
156908214	156908236	1	-	27760321	MOLM13	viability	TCGCACAGACATGCGCCGTTGG	PEAR1	ENSG00000187800	0.21609490145021365	[637,504]	[335,402]	1	hSpCas9	negative selection	5428467
156908818	156908840	1	-	27760321	MOLM13	viability	CGCGCCTCACCGTGTAACCCGG	PEAR1	ENSG00000187800	0.09608576980285977	[845,671]	[482,430]	0	hSpCas9	negative selection	5428468
156908995	156909017	1	+	27760321	MOLM13	viability	TCGCCTGCTCACCCATCGACGG	PEAR1	ENSG00000187800	0.05720170728763829	[1201,1021]	[763,553]	0	hSpCas9	negative selection	5428469
156893721	156893744	1	+	27661255	K562	viability	GTCAGGCTGGGGCTCGAAGTGGG	PEAR1	ENSG00000187800	0.08644046418613248	[795,778]	[780,571]	3	dCas9-KRAB	negative selection	5501163
156893746	156893769	1	-	27661255	K562	viability	GACAGCCGAGGACGGGGCGAGGG	PEAR1	ENSG00000187800	0.26486249273412266	[534,544]	[482,547]	8	dCas9-KRAB	negative selection	5501164
156893752	156893775	1	-	27661255	K562	viability	GGACTGGACAGCCGAGGACGGGG	PEAR1	ENSG00000187800	0.1689322939467236	[1131,1219]	[1153,969]	6	dCas9-KRAB	negative selection	5501165
156893758	156893781	1	-	27661255	K562	viability	GGAGGAGGACTGGACAGCCGAGG	PEAR1	ENSG00000187800	0.2546026867439506	[1416,1504]	[1447,1341]	8	dCas9-KRAB	negative selection	5501166
156893937	156893960	1	-	27661255	K562	viability	GGGGCCTCAGACTCCAGTCGAGG	PEAR1	ENSG00000187800	0.14432688301636765	[639,1029]	[798,672]	5	dCas9-KRAB	negative selection	5501167
156905314	156905337	1	+	27260156	BXPC3	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.1268887856440741	[506]	[589,496,692,530]	3	hSpCas9	negative selection	5562118
156905338	156905361	1	-	27260156	BXPC3	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.47049933516814624	[334]	[395,444,523,599]	8	hSpCas9	negative selection	5562119
156906696	156906719	1	+	27260156	BXPC3	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.27612008267792	[299]	[224,309,253,243]	-6	hSpCas9	negative selection	5562120
156906852	156906875	1	+	27260156	BXPC3	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.042701916694716346	[668]	[701,671,738,775]	0	hSpCas9	negative selection	5626370
156907679	156907702	1	+	27260156	BXPC3	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.10735861883904096	[200]	[209,205,165,193]	-2	hSpCas9	negative selection	5626371
156907656	156907679	1	+	27260156	BXPC3	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.3399671554252025	[350]	[417,436,484,529]	7	hSpCas9	negative selection	5626372
156905314	156905337	1	+	27260156	A673	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.09185229341591422	[506]	[731,583,672,613]	2	hSpCas9	negative selection	5683369
156905338	156905361	1	-	27260156	A673	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.6413299088475399	[334]	[614,589,579,728]	9	hSpCas9	negative selection	5683370
156906696	156906719	1	+	27260156	A673	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.06861249164495609	[299]	[309,333,356,369]	-2	hSpCas9	negative selection	5683371
156906852	156906875	1	+	27260156	A673	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.09206651143672695	[668]	[952,802,794,886]	2	hSpCas9	negative selection	5747621
156907679	156907702	1	+	27260156	A673	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.15574497177591073	[200]	[232,190,236,206]	-4	hSpCas9	negative selection	5747622
156907656	156907679	1	+	27260156	A673	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.31496319806002027	[350]	[541,472,488,599]	7	hSpCas9	negative selection	5747623
156905314	156905337	1	+	27260156	A375	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.4151096534503182	[506]	[735,871,792,767]	6	hSpCas9	negative selection	5804620
156905338	156905361	1	-	27260156	A375	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.7532220860494684	[334]	[741,650,767,493]	9	hSpCas9	negative selection	5804621
156906696	156906719	1	+	27260156	A375	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.14911165319838382	[299]	[440,162,318,318]	-2	hSpCas9	negative selection	5804622
156906852	156906875	1	+	27260156	A375	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.28894215395852973	[668]	[850,1015,994,959]	4	hSpCas9	negative selection	5868872
156907679	156907702	1	+	27260156	A375	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.38023896378772815	[200]	[173,217,236,105]	-5	hSpCas9	negative selection	5868873
156907656	156907679	1	+	27260156	A375	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.5359082057996023	[350]	[479,582,827,493]	7	hSpCas9	negative selection	5868874
156905314	156905337	1	+	27260156	COLO741	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.11827476879062884	[506]	[884,800,455]	2	hSpCas9	negative selection	5925871
156905338	156905361	1	-	27260156	COLO741	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.5119142292548224	[334]	[650,612,571]	8	hSpCas9	negative selection	5925872
156906696	156906719	1	+	27260156	COLO741	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.5038146769562594	[299]	[334,269,214]	-8	hSpCas9	negative selection	5925873
156906852	156906875	1	+	27260156	COLO741	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.08396257413866465	[668]	[941,780,712]	-2	hSpCas9	negative selection	5990123
156907679	156907702	1	+	27260156	COLO741	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.046883770771393385	[200]	[288,280,229]	1	hSpCas9	negative selection	5990124
156907656	156907679	1	+	27260156	COLO741	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.38124708590593215	[350]	[667,491,596]	7	hSpCas9	negative selection	5990125
156905314	156905337	1	+	27260156	CAL120	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.2058453122987094	[506]	[825,728,643]	3	hSpCas9	negative selection	6047122
156905338	156905361	1	-	27260156	CAL120	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	1.129498519404192	[334]	[1128,761,877]	9	hSpCas9	negative selection	6047123
156906696	156906719	1	+	27260156	CAL120	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.14021626296951795	[299]	[492,358,189]	-2	hSpCas9	negative selection	6047124
156906852	156906875	1	+	27260156	CAL120	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.05323977613255365	[668]	[938,728,759]	-1	hSpCas9	negative selection	6111374
156907679	156907702	1	+	27260156	CAL120	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.8384017256672838	[200]	[853,228,321]	9	hSpCas9	negative selection	6111375
156907656	156907679	1	+	27260156	CAL120	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.46518623759904965	[350]	[658,381,772]	7	hSpCas9	negative selection	6111376
156905314	156905337	1	+	27260156	CADOES1	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.5357857929584633	[506]	[559,605,821,748]	8	hSpCas9	negative selection	6168373
156905338	156905361	1	-	27260156	CADOES1	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.6988634504759726	[334]	[539,416,526,539]	9	hSpCas9	negative selection	6168374
156906696	156906719	1	+	27260156	CADOES1	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.8404132459896451	[299]	[171,149,100,201]	-9	hSpCas9	negative selection	6168375
156906852	156906875	1	+	27260156	CADOES1	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.16453329301002162	[668]	[773,663,659,690]	3	hSpCas9	negative selection	6232625
156907679	156907702	1	+	27260156	CADOES1	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.11486813560140052	[200]	[149,170,229,260]	2	hSpCas9	negative selection	6232626
156907656	156907679	1	+	27260156	CADOES1	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.5007155256993453	[350]	[487,466,571,314]	8	hSpCas9	negative selection	6232627
156905314	156905337	1	+	27260156	EWS502	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.34204213401299705	[506]	[595,778,769,574]	6	hSpCas9	negative selection	6289624
156905338	156905361	1	-	27260156	EWS502	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	1.043467250220673	[334]	[840,769,632,656]	9	hSpCas9	negative selection	6289625
156906696	156906719	1	+	27260156	EWS502	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.4805787591390257	[299]	[293,179,162,268]	-7	hSpCas9	negative selection	6289626
156906852	156906875	1	+	27260156	EWS502	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.16158822961190378	[668]	[656,897,862,759]	3	hSpCas9	negative selection	6353876
156907679	156907702	1	+	27260156	EWS502	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	1.1355142253037367	[200]	[898,294,357,254]	9	hSpCas9	negative selection	6353877
156907656	156907679	1	+	27260156	EWS502	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.5184893809001504	[350]	[529,573,555,461]	8	hSpCas9	negative selection	6353878
156905314	156905337	1	+	27260156	EW8	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.2600575490381261	[506]	[510,357,628,446]	5	hSpCas9	negative selection	6410875
156905338	156905361	1	-	27260156	EW8	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.6994494726392964	[334]	[439,540,445,334]	9	hSpCas9	negative selection	6410876
156906696	156906719	1	+	27260156	EW8	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.3896293380565713	[299]	[148,216,214,151]	-6	hSpCas9	negative selection	6410877
156906852	156906875	1	+	27260156	EW8	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.026266560935155225	[668]	[629,631,487,476]	0	hSpCas9	negative selection	6475127
156907679	156907702	1	+	27260156	EW8	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.24652404443298193	[200]	[133,264,182,185]	4	hSpCas9	negative selection	6475128
156907656	156907679	1	+	27260156	EW8	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.33459779846872695	[350]	[440,377,317,312]	6	hSpCas9	negative selection	6475129
156905314	156905337	1	+	27260156	CORL105	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.4663786820005997	[506]	[963,581,987,781]	8	hSpCas9	negative selection	6532126
156905338	156905361	1	-	27260156	CORL105	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	1.0167369784265223	[334]	[650,890,1019,640]	9	hSpCas9	negative selection	6532127
156906696	156906719	1	+	27260156	CORL105	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.18395850637322575	[299]	[302,346,310,274]	-3	hSpCas9	negative selection	6532128
156906852	156906875	1	+	27260156	CORL105	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.04571944858071775	[668]	[713,747,1041,763]	0	hSpCas9	negative selection	6596378
156907679	156907702	1	+	27260156	CORL105	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.03519805937221676	[200]	[248,268,251,195]	0	hSpCas9	negative selection	6596379
156907656	156907679	1	+	27260156	CORL105	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.5585526916481078	[350]	[638,425,763,620]	8	hSpCas9	negative selection	6596380
156905314	156905337	1	+	27260156	HS294T	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.8697046601934721	[506]	[601,250,237,312]	9	hSpCas9	negative selection	6653377
156905338	156905361	1	-	27260156	HS294T	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.8262083974636878	[334]	[149,374,163,231]	9	hSpCas9	negative selection	6653378
156906696	156906719	1	+	27260156	HS294T	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.7704178903498674	[299]	[87,33,75,73]	-8	hSpCas9	negative selection	6653379
156906852	156906875	1	+	27260156	HS294T	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.382695472496824	[668]	[157,216,213,208]	-5	hSpCas9	negative selection	6717629
156907679	156907702	1	+	27260156	HS294T	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.44378232694809605	[200]	[87,141,56,141]	6	hSpCas9	negative selection	6717630
156907656	156907679	1	+	27260156	HS294T	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.46637973734914806	[350]	[274,127,141,199]	6	hSpCas9	negative selection	6717631
156905314	156905337	1	+	27260156	HCC44	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.35857816727949376	[506]	[860,789,908,418]	6	hSpCas9	negative selection	6774628
156905338	156905361	1	-	27260156	HCC44	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.46516184133890925	[334]	[720,585,546,255]	7	hSpCas9	negative selection	6774629
156906696	156906719	1	+	27260156	HCC44	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.4456830683094918	[299]	[186,305,183,290]	-6	hSpCas9	negative selection	6774630
156906852	156906875	1	+	27260156	HCC44	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.0777600936748899	[668]	[891,755,751,485]	-1	hSpCas9	negative selection	6838880
156907679	156907702	1	+	27260156	HCC44	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.0032118539011998237	[200]	[196,248,209,243]	0	hSpCas9	negative selection	6838881
156907656	156907679	1	+	27260156	HCC44	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.4924794761304945	[350]	[447,466,749,598]	7	hSpCas9	negative selection	6838882
156905314	156905337	1	+	27260156	G402	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.9694773223473401	[506]	[1230,1224,870,1502]	9	hSpCas9	negative selection	6895879
156905338	156905361	1	-	27260156	G402	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.5007570961660897	[334]	[526,743,410,628]	6	hSpCas9	negative selection	6895880
156906696	156906719	1	+	27260156	G402	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-1.1732375471914858	[299]	[371,136,59,110]	-8	hSpCas9	negative selection	6895881
156906852	156906875	1	+	27260156	G402	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.18235525132842845	[668]	[832,872,1369,623]	2	hSpCas9	negative selection	6960131
156907679	156907702	1	+	27260156	G402	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.3325972837933465	[200]	[615,220,117,317]	4	hSpCas9	negative selection	6960132
156907656	156907679	1	+	27260156	G402	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.7918166358553527	[350]	[584,1418,428,555]	8	hSpCas9	negative selection	6960133
156905314	156905337	1	+	27260156	L33	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.302888567060939	[506]	[541,251,393,718]	6	hSpCas9	negative selection	7017130
156905338	156905361	1	-	27260156	L33	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.516578569535586	[334]	[684,169,269,382]	9	hSpCas9	negative selection	7017131
156906696	156906719	1	+	27260156	L33	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	0.2881983643140947	[299]	[365,152,171,450]	6	hSpCas9	negative selection	7017132
156906852	156906875	1	+	27260156	L33	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.07860268673578918	[668]	[609,241,348,776]	-2	hSpCas9	negative selection	7081382
156907679	156907702	1	+	27260156	L33	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.01970141149866045	[200]	[181,59,139,241]	0	hSpCas9	negative selection	7081383
156907656	156907679	1	+	27260156	L33	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.049134702498474125	[350]	[377,131,250,352]	1	hSpCas9	negative selection	7081384
156905314	156905337	1	+	27260156	K562	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.40468756104486364	[506]	[531,1025,504,361]	5	hSpCas9	negative selection	7138381
156905338	156905361	1	-	27260156	K562	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.7524478407728801	[334]	[720,608,515,212]	8	hSpCas9	negative selection	7138382
156906696	156906719	1	+	27260156	K562	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-1.3702874738768256	[299]	[81,41,211,73]	-8	hSpCas9	negative selection	7138383
156906852	156906875	1	+	27260156	K562	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.4014919032530161	[668]	[627,1168,749,613]	5	hSpCas9	negative selection	7202633
156907679	156907702	1	+	27260156	K562	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.3194329074957454	[200]	[118,86,286,363]	4	hSpCas9	negative selection	7202634
156907656	156907679	1	+	27260156	K562	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.15276997695424555	[350]	[278,249,298,523]	1	hSpCas9	negative selection	7202635
156905314	156905337	1	+	27260156	HT29	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.17746278223146178	[506]	[763,776,593,663]	3	hSpCas9	negative selection	7259632
156905338	156905361	1	-	27260156	HT29	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.6375847485021415	[334]	[612,419,971,518]	9	hSpCas9	negative selection	7259633
156906696	156906719	1	+	27260156	HT29	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.27060580588700023	[299]	[369,353,282,219]	-5	hSpCas9	negative selection	7259634
156906852	156906875	1	+	27260156	HT29	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.04020774470232036	[668]	[920,789,802,668]	-1	hSpCas9	negative selection	7323884
156907679	156907702	1	+	27260156	HT29	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.3821705232618019	[200]	[264,310,329,355]	7	hSpCas9	negative selection	7323885
156907656	156907679	1	+	27260156	HT29	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.38321029881154145	[350]	[593,595,515,525]	7	hSpCas9	negative selection	7323886
156905314	156905337	1	+	27260156	MHHES1	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.20489901458353776	[506]	[629,842,694,501]	4	hSpCas9	negative selection	7380883
156905338	156905361	1	-	27260156	MHHES1	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.7276111681823986	[334]	[753,461,684,590]	9	hSpCas9	negative selection	7380884
156906696	156906719	1	+	27260156	MHHES1	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.3320748575922028	[299]	[324,267,258,230]	-6	hSpCas9	negative selection	7380885
156906852	156906875	1	+	27260156	MHHES1	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.21138042073224633	[668]	[742,729,709,467]	-4	hSpCas9	negative selection	7445135
156907679	156907702	1	+	27260156	MHHES1	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.1446989752904193	[200]	[330,203,145,158]	-3	hSpCas9	negative selection	7445136
156907656	156907679	1	+	27260156	MHHES1	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.4152210723637125	[350]	[378,760,618,378]	7	hSpCas9	negative selection	7445137
156905314	156905337	1	+	27260156	MEWO	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.3746981266149691	[506]	[718,617,527]	7	hSpCas9	negative selection	7502134
156905338	156905361	1	-	27260156	MEWO	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.5547234350773015	[334]	[471,512,397]	9	hSpCas9	negative selection	7502135
156906696	156906719	1	+	27260156	MEWO	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.20751064382525608	[299]	[354,208,186]	-4	hSpCas9	negative selection	7502136
156906852	156906875	1	+	27260156	MEWO	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.14743409305057864	[668]	[847,597,663]	3	hSpCas9	negative selection	7566386
156907679	156907702	1	+	27260156	MEWO	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.06715146887779833	[200]	[169,98,267]	-1	hSpCas9	negative selection	7566387
156907656	156907679	1	+	27260156	MEWO	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.3342600057110825	[350]	[434,409,400]	7	hSpCas9	negative selection	7566388
156905314	156905337	1	+	27260156	LNCAPCLONEFGC	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.3107573638634812	[506]	[427,564,789,530]	5	hSpCas9	negative selection	7623385
156905338	156905361	1	-	27260156	LNCAPCLONEFGC	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.8701053950387003	[334]	[612,495,695,436]	9	hSpCas9	negative selection	7623386
156906696	156906719	1	+	27260156	LNCAPCLONEFGC	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.5853892918932205	[299]	[276,144,181,120]	-7	hSpCas9	negative selection	7623387
156906852	156906875	1	+	27260156	LNCAPCLONEFGC	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.3314684961297475	[668]	[547,398,465,514]	-5	hSpCas9	negative selection	7687637
156907679	156907702	1	+	27260156	LNCAPCLONEFGC	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.47966411640351225	[200]	[145,90,126,159]	-6	hSpCas9	negative selection	7687638
156907656	156907679	1	+	27260156	LNCAPCLONEFGC	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.3675239299814231	[350]	[415,416,470,344]	6	hSpCas9	negative selection	7687639
156905314	156905337	1	+	27260156	PANC0327	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.38615375603054325	[506]	[806,443,674,464]	6	hSpCas9	negative selection	7744636
156905338	156905361	1	-	27260156	PANC0327	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.19881723423783065	[334]	[278,489,387,184]	3	hSpCas9	negative selection	7744637
156906696	156906719	1	+	27260156	PANC0327	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.5950847763130959	[299]	[81,238,263,104]	-7	hSpCas9	negative selection	7744638
156906852	156906875	1	+	27260156	PANC0327	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.0027492206637903527	[668]	[956,445,444,572]	0	hSpCas9	negative selection	7808888
156907679	156907702	1	+	27260156	PANC0327	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.502081464424499	[200]	[288,232,274,219]	7	hSpCas9	negative selection	7808889
156907656	156907679	1	+	27260156	PANC0327	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.7671172166097372	[350]	[366,954,361,369]	9	hSpCas9	negative selection	7808890
156905314	156905337	1	+	27260156	NCIH2009	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.46279294160989964	[506]	[1232,1079,662]	6	hSpCas9	negative selection	7865887
156905338	156905361	1	-	27260156	NCIH2009	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.8081603957096031	[334]	[899,881,689]	9	hSpCas9	negative selection	7865888
156906696	156906719	1	+	27260156	NCIH2009	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.13717373754544682	[299]	[315,428,383]	-2	hSpCas9	negative selection	7865889
156906852	156906875	1	+	27260156	NCIH2009	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.09614171165563884	[668]	[1071,867,720]	-1	hSpCas9	negative selection	7930139
156907679	156907702	1	+	27260156	NCIH2009	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.7833246559109466	[200]	[169,139,180]	-7	hSpCas9	negative selection	7930140
156907656	156907679	1	+	27260156	NCIH2009	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.6804926482264209	[350]	[865,640,867]	8	hSpCas9	negative selection	7930141
156905314	156905337	1	+	27260156	NCIH1373	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.8867280684310075	[506]	[1256,810,1096,286]	8	hSpCas9	negative selection	7987138
156905338	156905361	1	-	27260156	NCIH1373	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	1.0863849942561976	[334]	[1065,677,614,233]	9	hSpCas9	negative selection	7987139
156906696	156906719	1	+	27260156	NCIH1373	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.4064111678244472	[299]	[420,191,123,82]	-4	hSpCas9	negative selection	7987140
156906852	156906875	1	+	27260156	NCIH1373	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.48898163291700747	[668]	[1359,633,1346,247]	5	hSpCas9	negative selection	8051390
156907679	156907702	1	+	27260156	NCIH1373	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.2916090707793766	[200]	[267,213,120,36]	-3	hSpCas9	negative selection	8051391
156907656	156907679	1	+	27260156	NCIH1373	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.5886805745695616	[350]	[733,715,368,145]	6	hSpCas9	negative selection	8051392
156905314	156905337	1	+	27260156	PATU8902	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.21677613016654879	[506]	[480,717,1104,912]	2	hSpCas9	negative selection	8108389
156905338	156905361	1	-	27260156	PATU8902	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	1.0591682119786976	[334]	[725,1468,749,1001]	9	hSpCas9	negative selection	8108390
156906696	156906719	1	+	27260156	PATU8902	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.33025203125345926	[299]	[437,298,275,325]	-3	hSpCas9	negative selection	8108391
156906852	156906875	1	+	27260156	PATU8902	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.06107118089203778	[668]	[1080,1236,759,840]	0	hSpCas9	negative selection	8172641
156907679	156907702	1	+	27260156	PATU8902	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.024399703192828026	[200]	[69,210,222,700]	0	hSpCas9	negative selection	8172642
156907656	156907679	1	+	27260156	PATU8902	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.3552356700469952	[350]	[878,828,407,407]	3	hSpCas9	negative selection	8172643
156905314	156905337	1	+	27260156	PANC1	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.28672168194900977	[506]	[439,756,484,488]	4	hSpCas9	negative selection	8229640
156905338	156905361	1	-	27260156	PANC1	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.8136167473893174	[334]	[435,708,578,358]	9	hSpCas9	negative selection	8229641
156906696	156906719	1	+	27260156	PANC1	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.008442683981545906	[299]	[212,401,247,197]	0	hSpCas9	negative selection	8229642
156906852	156906875	1	+	27260156	PANC1	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.2575923242260748	[668]	[653,779,597,717]	4	hSpCas9	negative selection	8293892
156907679	156907702	1	+	27260156	PANC1	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	0.0578074143627314	[200]	[206,206,216,102]	0	hSpCas9	negative selection	8293893
156907656	156907679	1	+	27260156	PANC1	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.7002376267159911	[350]	[515,736,412,356]	9	hSpCas9	negative selection	8293894
156905314	156905337	1	+	27260156	PANC0813	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.4999358559251263	[506]	[873,778,763,946]	7	hSpCas9	negative selection	8350891
156905338	156905361	1	-	27260156	PANC0813	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.7571105860489995	[334]	[651,554,518,916]	9	hSpCas9	negative selection	8350892
156906696	156906719	1	+	27260156	PANC0813	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	0.26531936593742383	[299]	[688,342,462,233]	4	hSpCas9	negative selection	8350893
156906852	156906875	1	+	27260156	PANC0813	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.19578930958281038	[668]	[487,711,655,858]	-3	hSpCas9	negative selection	8415143
156907679	156907702	1	+	27260156	PANC0813	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.34760596824625	[200]	[229,181,116,214]	-5	hSpCas9	negative selection	8415144
156907656	156907679	1	+	27260156	PANC0813	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.4968327434589048	[350]	[524,753,488,553]	7	hSpCas9	negative selection	8415145
156905314	156905337	1	+	27260156	RDES	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.3388106920689948	[506]	[593,629,825,955]	5	hSpCas9	negative selection	8472142
156905338	156905361	1	-	27260156	RDES	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.8015403665409457	[334]	[461,590,814,891]	9	hSpCas9	negative selection	8472143
156906696	156906719	1	+	27260156	RDES	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.6195933858583568	[299]	[210,199,272,211]	-8	hSpCas9	negative selection	8472144
156906852	156906875	1	+	27260156	RDES	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.004659769872892405	[668]	[710,697,859,824]	0	hSpCas9	negative selection	8536394
156907679	156907702	1	+	27260156	RDES	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.006258502375239505	[200]	[211,262,211,224]	0	hSpCas9	negative selection	8536395
156907656	156907679	1	+	27260156	RDES	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.45506123079057265	[350]	[491,548,532,648]	7	hSpCas9	negative selection	8536396
156905314	156905337	1	+	27260156	PC3	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.28190670050575506	[506]	[443,557,812,734]	6	hSpCas9	negative selection	8593393
156905338	156905361	1	-	27260156	PC3	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.4727632950122537	[334]	[235,617,788,385]	8	hSpCas9	negative selection	8593394
156906696	156906719	1	+	27260156	PC3	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.41459266702210107	[299]	[147,204,367,244]	-7	hSpCas9	negative selection	8593395
156906852	156906875	1	+	27260156	PC3	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.0987730339636575	[668]	[415,765,813,583]	-2	hSpCas9	negative selection	8657645
156907679	156907702	1	+	27260156	PC3	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.19086163840985826	[200]	[101,199,267,182]	-4	hSpCas9	negative selection	8657646
156907656	156907679	1	+	27260156	PC3	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.08924959017626793	[350]	[237,339,806,293]	2	hSpCas9	negative selection	8657647
156905314	156905337	1	+	27260156	PATU8988T	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	-0.09051483241491338	[506]	[337,526,469,515]	-1	hSpCas9	negative selection	8714644
156905338	156905361	1	-	27260156	PATU8988T	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.068894361048981	[334]	[197,400,293,482]	1	hSpCas9	negative selection	8714645
156906696	156906719	1	+	27260156	PATU8988T	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.04430607414672216	[299]	[182,346,348,247]	0	hSpCas9	negative selection	8714646
156906852	156906875	1	+	27260156	PATU8988T	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.10647966221158112	[668]	[543,713,661,481]	-2	hSpCas9	negative selection	8778896
156907679	156907702	1	+	27260156	PATU8988T	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.2910823902857016	[200]	[129,163,192,146]	-5	hSpCas9	negative selection	8778897
156907656	156907679	1	+	27260156	PATU8988T	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.2556210578129119	[350]	[336,398,457,425]	4	hSpCas9	negative selection	8778898
156905314	156905337	1	+	27260156	T47D	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.2642018448860624	[506]	[767,665,745,658]	5	hSpCas9	negative selection	8835895
156905338	156905361	1	-	27260156	T47D	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.6309705122183804	[334]	[666,520,578,659]	9	hSpCas9	negative selection	8835896
156906696	156906719	1	+	27260156	T47D	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.9360651597988169	[299]	[110,168,229,221]	-9	hSpCas9	negative selection	8835897
156906852	156906875	1	+	27260156	T47D	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.11682906142721822	[668]	[717,714,702,739]	-3	hSpCas9	negative selection	8900147
156907679	156907702	1	+	27260156	T47D	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.3257832976100097	[200]	[165,174,192,214]	-6	hSpCas9	negative selection	8900148
156907656	156907679	1	+	27260156	T47D	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.3080985638366345	[350]	[544,489,480,510]	6	hSpCas9	negative selection	8900149
156905314	156905337	1	+	27260156	SU8686	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.3428746445411925	[506]	[544,564,800,662]	6	hSpCas9	negative selection	8957146
156905338	156905361	1	-	27260156	SU8686	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.6961627507784014	[334]	[588,474,530,558]	9	hSpCas9	negative selection	8957147
156906696	156906719	1	+	27260156	SU8686	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.10373395750854275	[299]	[251,273,219,376]	-2	hSpCas9	negative selection	8957148
156906852	156906875	1	+	27260156	SU8686	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.1015093879779404	[668]	[639,713,735,768]	1	hSpCas9	negative selection	9021398
156907679	156907702	1	+	27260156	SU8686	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.44094648989764273	[200]	[150,171,125,129]	-6	hSpCas9	negative selection	9021399
156907656	156907679	1	+	27260156	SU8686	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.36123706467520095	[350]	[402,347,522,546]	6	hSpCas9	negative selection	9021400
156905314	156905337	1	+	27260156	SKES1	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.2715631622450359	[506]	[751,669,601,456]	6	hSpCas9	negative selection	9078397
156905338	156905361	1	-	27260156	SKES1	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.6431233406167705	[334]	[637,414,589,449]	9	hSpCas9	negative selection	9078398
156906696	156906719	1	+	27260156	SKES1	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.035113131925192054	[299]	[351,303,302,223]	0	hSpCas9	negative selection	9078399
156906852	156906875	1	+	27260156	SKES1	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.006044418573603272	[668]	[765,655,751,507]	0	hSpCas9	negative selection	9142649
156907679	156907702	1	+	27260156	SKES1	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.1561194098403038	[200]	[185,152,297,87]	-3	hSpCas9	negative selection	9142650
156907656	156907679	1	+	27260156	SKES1	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.2877512124325393	[350]	[463,425,439,384]	6	hSpCas9	negative selection	9142651
156905314	156905337	1	+	27260156	TOV112D	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.3238448329447583	[506]	[794,639,529,591]	6	hSpCas9	negative selection	9199648
156905338	156905361	1	-	27260156	TOV112D	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.7636017690876407	[334]	[547,922,369,522]	9	hSpCas9	negative selection	9199649
156906696	156906719	1	+	27260156	TOV112D	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.6529044838151504	[299]	[262,223,200,92]	-8	hSpCas9	negative selection	9199650
156906852	156906875	1	+	27260156	TOV112D	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	0.05493285565563355	[668]	[448,1162,636,629]	1	hSpCas9	negative selection	9263900
156907679	156907702	1	+	27260156	TOV112D	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.035444736412174604	[200]	[124,282,171,219]	0	hSpCas9	negative selection	9263901
156907656	156907679	1	+	27260156	TOV112D	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	-0.053952376150242176	[350]	[272,503,339,273]	-1	hSpCas9	negative selection	9263902
156905314	156905337	1	+	27260156	TC71	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.31648288417587983	[506]	[692,751,772,472]	7	hSpCas9	negative selection	9320899
156905338	156905361	1	-	27260156	TC71	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.4229731480934867	[334]	[510,390,401,632]	8	hSpCas9	negative selection	9320900
156906696	156906719	1	+	27260156	TC71	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.04327841345543071	[299]	[345,271,290,340]	-1	hSpCas9	negative selection	9320901
156906852	156906875	1	+	27260156	TC71	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.03422027922786641	[668]	[679,733,608,786]	-1	hSpCas9	negative selection	9385151
156907679	156907702	1	+	27260156	TC71	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.02655489037581793	[200]	[314,214,167,142]	0	hSpCas9	negative selection	9385152
156907656	156907679	1	+	27260156	TC71	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.35797906056704415	[350]	[567,422,392,549]	8	hSpCas9	negative selection	9385153
156905314	156905337	1	+	27260156	TC32	viability	GCCTCCGCAGGGTTGTATACCGG	PEAR1	ENSG00000187800	0.3056496669403905	[506]	[590,499,656,616]	5	hSpCas9	negative selection	9442150
156905338	156905361	1	-	27260156	TC32	viability	CTTCACCACCTGACGGTACACGG	PEAR1	ENSG00000187800	0.4919584545386513	[334]	[452,230,653,528]	8	hSpCas9	negative selection	9442151
156906696	156906719	1	+	27260156	TC32	viability	AGCTCGTGTGATCCCAAGAGTGG	PEAR1	ENSG00000187800	-0.8362461543600156	[299]	[184,60,213,208]	-9	hSpCas9	negative selection	9442152
156906852	156906875	1	+	27260156	TC32	viability	TTCTGCCCCGCAGAGAGAACTGG	PEAR1	ENSG00000187800	-0.10767046716515782	[668]	[410,460,845,702]	-2	hSpCas9	negative selection	9506402
156907679	156907702	1	+	27260156	TC32	viability	AGGTGTCTTCCAAACCCCACAGG	PEAR1	ENSG00000187800	-0.3332792764654815	[200]	[145,60,291,151]	-6	hSpCas9	negative selection	9506403
156907656	156907679	1	+	27260156	TC32	viability	AGCACCCATTCTTGCCAAAATGG	PEAR1	ENSG00000187800	0.5539423285360372	[350]	[585,271,533,598]	8	hSpCas9	negative selection	9506404
156903968	156903991	1	-	27869803	HPAFII	viability after 27 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	-0.6639547002689389	[219]	[120,32,NaN]	-5	hSpCas9	negative selection	9529614
156905373	156905396	1	+	27869803	HPAFII	viability after 27 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.4164192540646639	[180]	[120,131,NaN]	3	hSpCas9	negative selection	9529615
156906304	156906327	1	-	27869803	HPAFII	viability after 27 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.5866385726093701	[275]	[242,196,NaN]	5	hSpCas9	negative selection	9529616
156906789	156906812	1	-	27869803	HPAFII	viability after 27 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	-0.3866453211506786	[483]	[348,65,NaN]	-3	hSpCas9	negative selection	9529617
156907719	156907742	1	-	27869803	HPAFII	viability after 27 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	0.6221542820946041	[161]	[195,76,NaN]	5	hSpCas9	negative selection	9529618
156907969	156907992	1	+	27869803	HPAFII	viability after 27 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	-0.022059529731825456	[475]	[240,250,NaN]	0	hSpCas9	negative selection	9529619
156903968	156903991	1	-	27869803	HPAFII	viability after 15 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	-0.831815810505605	[219]	[175,105,NaN]	-7	hSpCas9	negative selection	9612063
156905373	156905396	1	+	27869803	HPAFII	viability after 15 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.1750696007696692	[180]	[292,173,NaN]	2	hSpCas9	negative selection	9612064
156906304	156906327	1	-	27869803	HPAFII	viability after 15 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	-0.02385310741619473	[275]	[411,216,NaN]	0	hSpCas9	negative selection	9612065
156906789	156906812	1	-	27869803	HPAFII	viability after 15 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	-0.0771662117707157	[483]	[608,420,NaN]	-1	hSpCas9	negative selection	9612066
156907719	156907742	1	-	27869803	HPAFII	viability after 15 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	0.31545814103181113	[161]	[310,157,NaN]	3	hSpCas9	negative selection	9612067
156907969	156907992	1	+	27869803	HPAFII	viability after 15 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.17674207546030696	[475]	[687,509,NaN]	2	hSpCas9	negative selection	9612068
156903968	156903991	1	-	27869803	ASPC1	viability after 36 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.5271072047267521	[536]	[6,337,397]	5	hSpCas9	negative selection	9694512
156905373	156905396	1	+	27869803	ASPC1	viability after 36 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.6716412180735689	[357]	[89,210,263]	6	hSpCas9	negative selection	9694513
156906304	156906327	1	-	27869803	ASPC1	viability after 36 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	-0.49918394662609167	[747]	[174,182,190]	-5	hSpCas9	negative selection	9694514
156906789	156906812	1	-	27869803	ASPC1	viability after 36 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.7803480154780935	[1170]	[882,1056,285]	7	hSpCas9	negative selection	9694515
156907719	156907742	1	-	27869803	ASPC1	viability after 36 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	1.3645899929695862	[360]	[187,448,317]	9	hSpCas9	negative selection	9694516
156907969	156907992	1	+	27869803	ASPC1	viability after 36 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	-0.12512818505804113	[1181]	[309,321,466]	-1	hSpCas9	negative selection	9694517
156903968	156903991	1	-	27869803	PATU8988S	viability after 35 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.4436798096639922	[284]	[205,105,NaN]	5	hSpCas9	negative selection	9776961
156905373	156905396	1	+	27869803	PATU8988S	viability after 35 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	-0.4948762712571736	[342]	[110,84,NaN]	-5	hSpCas9	negative selection	9776962
156906304	156906327	1	-	27869803	PATU8988S	viability after 35 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	-0.4276514065698729	[695]	[166,249,NaN]	-4	hSpCas9	negative selection	9776963
156906789	156906812	1	-	27869803	PATU8988S	viability after 35 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.030021638178499788	[1033]	[293,556,NaN]	0	hSpCas9	negative selection	9776964
156907719	156907742	1	-	27869803	PATU8988S	viability after 35 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	0.15609883397888602	[359]	[186,135,NaN]	1	hSpCas9	negative selection	9776965
156907969	156907992	1	+	27869803	PATU8988S	viability after 35 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	-0.32862199990901364	[1033]	[380,281,NaN]	-3	hSpCas9	negative selection	9776966
156903968	156903991	1	-	27869803	PATU8988S	viability after 31 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	0.45709324189828615	[284]	[177,127,NaN]	5	hSpCas9	negative selection	9859410
156905373	156905396	1	+	27869803	PATU8988S	viability after 31 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.06342706300895451	[342]	[123,166,NaN]	0	hSpCas9	negative selection	9859411
156906304	156906327	1	-	27869803	PATU8988S	viability after 31 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.19793867106410978	[695]	[210,454,NaN]	2	hSpCas9	negative selection	9859412
156906789	156906812	1	-	27869803	PATU8988S	viability after 31 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.13208275773271738	[1033]	[208,760,NaN]	1	hSpCas9	negative selection	9859413
156907719	156907742	1	-	27869803	PATU8988S	viability after 31 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	-0.06230034371429394	[359]	[140,132,NaN]	0	hSpCas9	negative selection	9859414
156907969	156907992	1	+	27869803	PATU8988S	viability after 31 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	-0.13207724107548036	[1033]	[333,429,NaN]	-1	hSpCas9	negative selection	9859415
156903968	156903991	1	-	27869803	HPAFII	viability after 35 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	-0.9206931340968962	[219]	[79,34,NaN]	-5	hSpCas9	negative selection	9941859
156905373	156905396	1	+	27869803	HPAFII	viability after 35 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	-0.8688917814980607	[180]	[44,55,NaN]	-5	hSpCas9	negative selection	9941860
156906304	156906327	1	-	27869803	HPAFII	viability after 35 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.6493923055145954	[275]	[181,260,NaN]	4	hSpCas9	negative selection	9941861
156906789	156906812	1	-	27869803	HPAFII	viability after 35 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	0.3154232665438945	[483]	[461,127,NaN]	2	hSpCas9	negative selection	9941862
156907719	156907742	1	-	27869803	HPAFII	viability after 35 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	0.8656870473465702	[161]	[211,78,NaN]	6	hSpCas9	negative selection	9941863
156907969	156907992	1	+	27869803	HPAFII	viability after 35 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.5514896165670903	[475]	[101,635,NaN]	3	hSpCas9	negative selection	9941864
156903968	156903991	1	-	27869803	HPAFII	viability after 31 days	TGAGAGTTCCAGCCAGCCGCAGG	PEAR1	ENSG00000187800	-0.6861622267526878	[219]	[81,70,NaN]	-4	hSpCas9	negative selection	10024308
156905373	156905396	1	+	27869803	HPAFII	viability after 31 days	CAGCGCCTGCAGTGCTGCCATGG	PEAR1	ENSG00000187800	0.08152642917028097	[180]	[95,119,NaN]	0	hSpCas9	negative selection	10024309
156906304	156906327	1	-	27869803	HPAFII	viability after 31 days	ACTGATTGGGTGCCACACAACGG	PEAR1	ENSG00000187800	0.3150595043054473	[275]	[118,272,NaN]	2	hSpCas9	negative selection	10024310
156906789	156906812	1	-	27869803	HPAFII	viability after 31 days	TGGCAGCGGAACTGGCAGGCAGG	PEAR1	ENSG00000187800	-0.1622494565493362	[483]	[381,90,NaN]	-1	hSpCas9	negative selection	10024311
156907719	156907742	1	-	27869803	HPAFII	viability after 31 days	ACCCTCCATACCATCCAGCCAGG	PEAR1	ENSG00000187800	0.39946686125996267	[161]	[173,60,NaN]	3	hSpCas9	negative selection	10024312
156907969	156907992	1	+	27869803	HPAFII	viability after 31 days	CAGGAATGTCGCTGCCACAACGG	PEAR1	ENSG00000187800	0.05938375066173107	[475]	[118,451,NaN]	0	hSpCas9	negative selection	10024313
156903933	156903956	1	-	28162770	P31FUJ	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-1.982823951406031	[73]	[21]	-8	hSpCas9	negative selection	10209429
156913199	156913222	1	-	28162770	P31FUJ	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	0.5625800759771493	[120]	[209]	6	hSpCas9	negative selection	10209430
156904756	156904779	1	-	28162770	P31FUJ	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	0.3330514733590729	[303]	[449]	3	hSpCas9	negative selection	10209431
156906772	156906795	1	-	28162770	P31FUJ	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	0.7671977955856213	[79]	[159]	8	hSpCas9	negative selection	10209432
156907972	156907995	1	+	28162770	P31FUJ	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	0.18582855958847344	[400]	[535]	2	hSpCas9	negative selection	10209433
156908308	156908331	1	-	28162770	P31FUJ	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	-0.322439416899055	[82]	[77]	-3	hSpCas9	negative selection	10209434
156908706	156908729	1	-	28162770	P31FUJ	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	1.166986467795517	[320]	[846]	9	hSpCas9	negative selection	10209435
156908720	156908743	1	+	28162770	P31FUJ	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	0.9788565553371152	[211]	[490]	9	hSpCas9	negative selection	10209436
156908992	156909015	1	-	28162770	P31FUJ	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.7221870451533037	[437]	[311]	-5	hSpCas9	negative selection	10209437
156909783	156909806	1	-	28162770	P31FUJ	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	1.2067774791272567	[152]	[414]	9	hSpCas9	negative selection	10209438
156903933	156903956	1	-	28162770	TF1	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10378795
156913199	156913222	1	-	28162770	TF1	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10378796
156904756	156904779	1	-	28162770	TF1	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10378797
156906772	156906795	1	-	28162770	TF1	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10378798
156907972	156907995	1	+	28162770	TF1	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	NaN	[NaN]	[359]	1	hSpCas9	negative selection	10378799
156908308	156908331	1	-	28162770	TF1	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10378800
156908706	156908729	1	-	28162770	TF1	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	NaN	[NaN]	[270]	1	hSpCas9	negative selection	10378801
156908720	156908743	1	+	28162770	TF1	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10378802
156908992	156909015	1	-	28162770	TF1	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10378803
156909783	156909806	1	-	28162770	TF1	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10378804
156903933	156903956	1	-	28162770	SKM1	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-1.2814333166593026	[21]	[15]	-7	hSpCas9	negative selection	10548161
156913199	156913222	1	-	28162770	SKM1	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	-1.5138794026596734	[20]	[12]	-7	hSpCas9	negative selection	10548162
156904756	156904779	1	-	28162770	SKM1	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-0.9475325801058645	[95]	[87]	-6	hSpCas9	negative selection	10548163
156906772	156906795	1	-	28162770	SKM1	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	0.34149703426087386	[24]	[55]	3	hSpCas9	negative selection	10548164
156907972	156907995	1	+	28162770	SKM1	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	0.4066226770259569	[98]	[231]	4	hSpCas9	negative selection	10548165
156908308	156908331	1	-	28162770	SKM1	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	0.025995208532944458	[24]	[44]	0	hSpCas9	negative selection	10548166
156908706	156908729	1	-	28162770	SKM1	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	-0.1574220292374815	[93]	[148]	-1	hSpCas9	negative selection	10548167
156908720	156908743	1	+	28162770	SKM1	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	1.368329514082144	[38]	[177]	9	hSpCas9	negative selection	10548168
156908992	156909015	1	-	28162770	SKM1	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.3884915386716829	[96]	[130]	-3	hSpCas9	negative selection	10548169
156909783	156909806	1	-	28162770	SKM1	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	-0.22535739225321383	[40]	[61]	-2	hSpCas9	negative selection	10548170
156903933	156903956	1	-	28162770	SKM1	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-1.2814333166593026	[21]	[15]	-7	hSpCas9	negative selection	10717527
156913199	156913222	1	-	28162770	SKM1	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	-1.5138794026596734	[20]	[12]	-7	hSpCas9	negative selection	10717528
156904756	156904779	1	-	28162770	SKM1	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-0.9475325801058645	[95]	[87]	-6	hSpCas9	negative selection	10717529
156906772	156906795	1	-	28162770	SKM1	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	0.34149703426087386	[24]	[55]	3	hSpCas9	negative selection	10717530
156907972	156907995	1	+	28162770	SKM1	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	0.4066226770259569	[98]	[231]	4	hSpCas9	negative selection	10717531
156908308	156908331	1	-	28162770	SKM1	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	0.025995208532944458	[24]	[44]	0	hSpCas9	negative selection	10717532
156908706	156908729	1	-	28162770	SKM1	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	-0.1574220292374815	[93]	[148]	-1	hSpCas9	negative selection	10717533
156908720	156908743	1	+	28162770	SKM1	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	1.368329514082144	[38]	[177]	9	hSpCas9	negative selection	10717534
156908992	156909015	1	-	28162770	SKM1	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.3884915386716829	[96]	[130]	-3	hSpCas9	negative selection	10717535
156909783	156909806	1	-	28162770	SKM1	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	-0.22535739225321383	[40]	[61]	-2	hSpCas9	negative selection	10717536
156903933	156903956	1	-	28162770	PL21	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-0.9022221031403577	[72]	[16]	-6	hSpCas9	negative selection	10886893
156913199	156913222	1	-	28162770	PL21	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	0.8154757642539949	[46]	[35]	7	hSpCas9	negative selection	10886894
156904756	156904779	1	-	28162770	PL21	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-1.5095186336811508	[313]	[47]	-7	hSpCas9	negative selection	10886895
156906772	156906795	1	-	28162770	PL21	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	-1.3023607260398629	[84]	[14]	-7	hSpCas9	negative selection	10886896
156907972	156907995	1	+	28162770	PL21	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	-0.8420886208999774	[415]	[100]	-5	hSpCas9	negative selection	10886897
156908308	156908331	1	-	28162770	PL21	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	0.48132136703337336	[78]	[47]	4	hSpCas9	negative selection	10886898
156908706	156908729	1	-	28162770	PL21	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	-0.3212067869358645	[243]	[84]	-2	hSpCas9	negative selection	10886899
156908720	156908743	1	+	28162770	PL21	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	-0.37359563080858205	[127]	[42]	-3	hSpCas9	negative selection	10886900
156908992	156909015	1	-	28162770	PL21	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.7666935215754807	[257]	[65]	-5	hSpCas9	negative selection	10886901
156909783	156909806	1	-	28162770	PL21	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	0.2899362848399659	[108]	[57]	2	hSpCas9	negative selection	10886902
156903933	156903956	1	-	28162770	P31FUJ	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-1.982823951406031	[73]	[21]	-8	hSpCas9	negative selection	11056259
156913199	156913222	1	-	28162770	P31FUJ	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	0.5625800759771493	[120]	[209]	6	hSpCas9	negative selection	11056260
156904756	156904779	1	-	28162770	P31FUJ	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	0.3330514733590729	[303]	[449]	3	hSpCas9	negative selection	11056261
156906772	156906795	1	-	28162770	P31FUJ	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	0.7671977955856213	[79]	[159]	8	hSpCas9	negative selection	11056262
156907972	156907995	1	+	28162770	P31FUJ	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	0.18582855958847344	[400]	[535]	2	hSpCas9	negative selection	11056263
156908308	156908331	1	-	28162770	P31FUJ	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	-0.322439416899055	[82]	[77]	-3	hSpCas9	negative selection	11056264
156908706	156908729	1	-	28162770	P31FUJ	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	1.166986467795517	[320]	[846]	9	hSpCas9	negative selection	11056265
156908720	156908743	1	+	28162770	P31FUJ	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	0.9788565553371152	[211]	[490]	9	hSpCas9	negative selection	11056266
156908992	156909015	1	-	28162770	P31FUJ	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.7221870451533037	[437]	[311]	-5	hSpCas9	negative selection	11056267
156909783	156909806	1	-	28162770	P31FUJ	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	1.2067774791272567	[152]	[414]	9	hSpCas9	negative selection	11056268
156903933	156903956	1	-	28162770	OCIAML5	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-4.552506289005089	[38]	[2]	-9	hSpCas9	negative selection	11225625
156913199	156913222	1	-	28162770	OCIAML5	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	-0.4687379313124913	[45]	[59]	-3	hSpCas9	negative selection	11225626
156904756	156904779	1	-	28162770	OCIAML5	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-0.8938867465586242	[174]	[169]	-5	hSpCas9	negative selection	11225627
156906772	156906795	1	-	28162770	OCIAML5	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	-0.7220060302996243	[52]	[57]	-5	hSpCas9	negative selection	11225628
156907972	156907995	1	+	28162770	OCIAML5	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	-0.0021511865783472306	[166]	[300]	0	hSpCas9	negative selection	11225629
156908308	156908331	1	-	28162770	OCIAML5	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	-0.6885678385811176	[74]	[83]	-4	hSpCas9	negative selection	11225630
156908706	156908729	1	-	28162770	OCIAML5	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	0.4698615240233655	[129]	[324]	4	hSpCas9	negative selection	11225631
156908720	156908743	1	+	28162770	OCIAML5	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	-0.6244658585247878	[157]	[184]	-4	hSpCas9	negative selection	11225632
156908992	156909015	1	-	28162770	OCIAML5	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.5468817398112109	[207]	[256]	-4	hSpCas9	negative selection	11225633
156909783	156909806	1	-	28162770	OCIAML5	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	0.2699239535146134	[84]	[184]	2	hSpCas9	negative selection	11225634
156903933	156903956	1	-	28162770	EOL1	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-0.7303167423807779	[147]	[46]	-5	hSpCas9	negative selection	11394991
156913199	156913222	1	-	28162770	EOL1	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	0.8329172961049667	[64]	[60]	7	hSpCas9	negative selection	11394992
156904756	156904779	1	-	28162770	EOL1	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	0.03888044704952964	[581]	[314]	0	hSpCas9	negative selection	11394993
156906772	156906795	1	-	28162770	EOL1	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	1.3370430762869252	[141]	[188]	9	hSpCas9	negative selection	11394994
156907972	156907995	1	+	28162770	EOL1	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	0.5887175401382474	[755]	[598]	5	hSpCas9	negative selection	11394995
156908308	156908331	1	-	28162770	EOL1	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	-0.7288944670333882	[150]	[47]	-5	hSpCas9	negative selection	11394996
156908706	156908729	1	-	28162770	EOL1	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	-0.30241737955573744	[315]	[134]	-2	hSpCas9	negative selection	11394997
156908720	156908743	1	+	28162770	EOL1	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	-0.32857116539817655	[173]	[72]	-2	hSpCas9	negative selection	11394998
156908992	156909015	1	-	28162770	EOL1	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.23388159103394845	[499]	[223]	-2	hSpCas9	negative selection	11394999
156909783	156909806	1	-	28162770	EOL1	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	-0.7679431934550668	[180]	[55]	-5	hSpCas9	negative selection	11395000
156903933	156903956	1	-	28162770	MOLM13	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-0.0436109572355563	[66]	[46]	0	hSpCas9	negative selection	11564357
156913199	156913222	1	-	28162770	MOLM13	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	0.16722990341086752	[100]	[81]	1	hSpCas9	negative selection	11564358
156904756	156904779	1	-	28162770	MOLM13	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	0.4807134219021624	[447]	[451]	3	hSpCas9	negative selection	11564359
156906772	156906795	1	-	28162770	MOLM13	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	-0.2901378281494569	[114]	[67]	-2	hSpCas9	negative selection	11564360
156907972	156907995	1	+	28162770	MOLM13	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	-0.1469886970808647	[535]	[349]	-1	hSpCas9	negative selection	11564361
156908308	156908331	1	-	28162770	MOLM13	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	0.6439197456360781	[130]	[147]	5	hSpCas9	negative selection	11564362
156908706	156908729	1	-	28162770	MOLM13	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	0.04917622412233663	[392]	[293]	0	hSpCas9	negative selection	11564363
156908720	156908743	1	+	28162770	MOLM13	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	-0.6171921193451892	[226]	[106]	-4	hSpCas9	negative selection	11564364
156908992	156909015	1	-	28162770	MOLM13	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.8150445817269198	[437]	[179]	-4	hSpCas9	negative selection	11564365
156909783	156909806	1	-	28162770	MOLM13	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	0.10135039995692519	[155]	[120]	0	hSpCas9	negative selection	11564366
156903933	156903956	1	-	28162770	HEL	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-1.3827962601067805	[113]	[27]	-7	hSpCas9	negative selection	11733723
156913199	156913222	1	-	28162770	HEL	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	-0.5552005456115516	[38]	[16]	-4	hSpCas9	negative selection	11733724
156904756	156904779	1	-	28162770	HEL	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-0.4962801278562403	[380]	[172]	-3	hSpCas9	negative selection	11733725
156906772	156906795	1	-	28162770	HEL	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	-0.023837434274451397	[99]	[62]	0	hSpCas9	negative selection	11733726
156907972	156907995	1	+	28162770	HEL	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	-0.0752851985123889	[453]	[275]	0	hSpCas9	negative selection	11733727
156908308	156908331	1	-	28162770	HEL	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	1.1266152076071987	[132]	[185]	8	hSpCas9	negative selection	11733728
156908706	156908729	1	-	28162770	HEL	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	0.06504433174324004	[296]	[198]	0	hSpCas9	negative selection	11733729
156908720	156908743	1	+	28162770	HEL	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	0.3797044261665631	[161]	[134]	3	hSpCas9	negative selection	11733730
156908992	156909015	1	-	28162770	HEL	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.18276343676750662	[419]	[236]	-1	hSpCas9	negative selection	11733731
156909783	156909806	1	-	28162770	HEL	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	0.3146846343161531	[117]	[93]	2	hSpCas9	negative selection	11733732
156903933	156903956	1	-	28162770	MV411	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	0.8244948534185854	[60]	[90]	7	hSpCas9	negative selection	11903089
156913199	156913222	1	-	28162770	MV411	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	1.3018853348051516	[38]	[80]	9	hSpCas9	negative selection	11903090
156904756	156904779	1	-	28162770	MV411	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-1.1109079427402075	[340]	[132]	-6	hSpCas9	negative selection	11903091
156906772	156906795	1	-	28162770	MV411	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	0.025045129446327197	[62]	[53]	0	hSpCas9	negative selection	11903092
156907972	156907995	1	+	28162770	MV411	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	0.06745888467653993	[323]	[285]	0	hSpCas9	negative selection	11903093
156908308	156908331	1	-	28162770	MV411	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	1.3988021423183596	[112]	[250]	9	hSpCas9	negative selection	11903094
156908706	156908729	1	-	28162770	MV411	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	-0.2865879847131555	[319]	[220]	-2	hSpCas9	negative selection	11903095
156908720	156908743	1	+	28162770	MV411	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	0.029014031649273075	[120]	[103]	0	hSpCas9	negative selection	11903096
156908992	156909015	1	-	28162770	MV411	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-1.3542036910850113	[260]	[85]	-7	hSpCas9	negative selection	11903097
156909783	156909806	1	-	28162770	MV411	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	0.7344862949770075	[126]	[177]	6	hSpCas9	negative selection	11903098
156903933	156903956	1	-	28162770	MONOMAC1	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-0.849113543639247	[54]	[34]	-6	hSpCas9	negative selection	12072455
156913199	156913222	1	-	28162770	MONOMAC1	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	0.5399287471066527	[23]	[39]	5	hSpCas9	negative selection	12072456
156904756	156904779	1	-	28162770	MONOMAC1	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	0.34017252221323435	[214]	[311]	3	hSpCas9	negative selection	12072457
156906772	156906795	1	-	28162770	MONOMAC1	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	0.6311968046739664	[48]	[86]	6	hSpCas9	negative selection	12072458
156907972	156907995	1	+	28162770	MONOMAC1	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	-0.20298611339074002	[242]	[241]	-2	hSpCas9	negative selection	12072459
156908308	156908331	1	-	28162770	MONOMAC1	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	-0.26979318949486797	[60]	[57]	-2	hSpCas9	negative selection	12072460
156908706	156908729	1	-	28162770	MONOMAC1	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	0.4872402075797921	[144]	[232]	5	hSpCas9	negative selection	12072461
156908720	156908743	1	+	28162770	MONOMAC1	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	0.10034906356501722	[82]	[101]	1	hSpCas9	negative selection	12072462
156908992	156909015	1	-	28162770	MONOMAC1	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.7420329404630652	[177]	[121]	-6	hSpCas9	negative selection	12072463
156909783	156909806	1	-	28162770	MONOMAC1	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	-0.1375358353108918	[94]	[98]	-1	hSpCas9	negative selection	12072464
156903933	156903956	1	-	28162770	OCIAML2	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-0.8032051643290321	[16]	[53]	-5	hSpCas9	negative selection	12241821
156913199	156913222	1	-	28162770	OCIAML2	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	-0.9300614438794585	[10]	[31]	-6	hSpCas9	negative selection	12241822
156904756	156904779	1	-	28162770	OCIAML2	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-0.6226329186872113	[54]	[197]	-5	hSpCas9	negative selection	12241823
156906772	156906795	1	-	28162770	OCIAML2	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	-0.08235923552610291	[16]	[88]	0	hSpCas9	negative selection	12241824
156907972	156907995	1	+	28162770	OCIAML2	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	0.009517770435234496	[87]	[490]	0	hSpCas9	negative selection	12241825
156908308	156908331	1	-	28162770	OCIAML2	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	-0.5580926664925008	[16]	[63]	-4	hSpCas9	negative selection	12241826
156908706	156908729	1	-	28162770	OCIAML2	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	0.1770684308269575	[44]	[281]	1	hSpCas9	negative selection	12241827
156908720	156908743	1	+	28162770	OCIAML2	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	0.14995658520971633	[19]	[122]	1	hSpCas9	negative selection	12241828
156908992	156909015	1	-	28162770	OCIAML2	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-0.8796685838995619	[79]	[240]	-6	hSpCas9	negative selection	12241829
156909783	156909806	1	-	28162770	OCIAML2	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	-0.21966825170894239	[24]	[118]	-2	hSpCas9	negative selection	12241830
156903933	156903956	1	-	28162770	OCIAML3	viability	AGAAGGAGGGGACACAGAGGCGG	PEAR1	ENSG00000187800	-1.8350157398279578	[25]	[21]	-8	hSpCas9	negative selection	12411187
156913199	156913222	1	-	28162770	OCIAML3	viability	TAGTAGTGACTGTAGCTCGGAGG	PEAR1	ENSG00000187800	0.10198617278573674	[24]	[80]	1	hSpCas9	negative selection	12411188
156904756	156904779	1	-	28162770	OCIAML3	viability	GGAGTGGGACTCCTTGGTGGTGG	PEAR1	ENSG00000187800	-2.8981610334835493	[120]	[48]	-9	hSpCas9	negative selection	12411189
156906772	156906795	1	-	28162770	OCIAML3	viability	GGCAGGGCCATAGTAGCCAGGGG	PEAR1	ENSG00000187800	-0.12270192139857428	[21]	[60]	-1	hSpCas9	negative selection	12411190
156907972	156907995	1	+	28162770	OCIAML3	viability	GAATGTCGCTGCCACAACGGCGG	PEAR1	ENSG00000187800	-0.5940076403241632	[104]	[209]	-4	hSpCas9	negative selection	12411191
156908308	156908331	1	-	28162770	OCIAML3	viability	GCTCCCGGTCGCAGGTGCAGGGG	PEAR1	ENSG00000187800	-0.2720795454368007	[27]	[69]	-2	hSpCas9	negative selection	12411192
156908706	156908729	1	-	28162770	OCIAML3	viability	GCGGGCAGCTCTCGTTGCAGTGG	PEAR1	ENSG00000187800	1.8695816037867905	[62]	[694]	9	hSpCas9	negative selection	12411193
156908720	156908743	1	+	28162770	OCIAML3	viability	GCTGCCCGCAGGACACGCATGGG	PEAR1	ENSG00000187800	0.939970931678188	[23]	[138]	7	hSpCas9	negative selection	12411194
156908992	156909015	1	-	28162770	OCIAML3	viability	GTCGATGGGTGAGCAGGCGATGG	PEAR1	ENSG00000187800	-1.1719837107292124	[102]	[137]	-7	hSpCas9	negative selection	12411195
156909783	156909806	1	-	28162770	OCIAML3	viability	CTGAAGCCCCAGGTTCCGGGTGG	PEAR1	ENSG00000187800	0.7279204545631991	[40]	[204]	6	hSpCas9	negative selection	12411196